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Items 1 to 31 of about 31
1. Takeda T, Nishiyama T, Ohara R, Hasegawa S: [Vesicovaginal fistula after sexual intercourse: a case report]. Hinyokika Kiyo; 2007 Mar;53(3):191-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • She had been diagnosed with carcinoma of uterine cervix stage I b2 and had undergone radical hysterectomy and radiation therapy (45 Gy).
  • [MeSH-minor] Female. Humans. Middle Aged. Postoperative Period. Uterine Cervical Neoplasms / radiotherapy. Uterine Cervical Neoplasms / surgery

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  • (PMID = 17447491.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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2. Park SY, Bae DS, Nam JH, Park CT, Cho CH, Lee JM, Lee MK, Kim SH, Park SM, Yun YH: Quality of life and sexual problems in disease-free survivors of cervical cancer compared with the general population. Cancer; 2007 Dec 15;110(12):2716-25
MedlinePlus Health Information. consumer health - Cervical Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Quality of life and sexual problems in disease-free survivors of cervical cancer compared with the general population.
  • BACKGROUND: The purpose of this study was to identify problems related to long-term quality of life (QOL) and sexual function in cervical cancer survivors.
  • METHODS: The authors enrolled 860 women (median time since diagnosis, 5.86 years) with a history of cervical cancer (stage I to IVa) who had been treated at any of 6 hospitals from 1983 through 2004 and 494 control subjects selected randomly from a representative sample of Korean women.
  • Subjects filled out a questionnaire that included the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30, its Cervical Cancer Module, and additional sexual function items.
  • RESULTS: Cervical cancer survivors had clinically significant worse problems with social functioning, constipation, diarrhea, and difficulties with their finances than controls (P < .01).
  • CONCLUSIONS: These findings can increase the awareness of healthcare providers to the potential need for counseling and other interventions among women who have been successfully treated for cervical cancer and could help them improve their impaired QOL.
  • [MeSH-major] Quality of Life. Sexual Behavior. Survivors. Uterine Cervical Neoplasms / psychology

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  • [Copyright] 2007 American Cancer Society
  • (PMID = 17960806.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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3. Qi Y, Huang JS, Wang DD, Zhang F, Zhang SL: [Expressions of HLA class I antigen and CD8 and their clinical significance in cervical cancer]. Nan Fang Yi Ke Da Xue Xue Bao; 2008 Dec;28(12):2165-9
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Expressions of HLA class I antigen and CD8 and their clinical significance in cervical cancer].
  • OBJECTIVE: To examine the expressions of HLA class I antigen and CD8 in various cervical diseases and investigate their association with cervical cancer.
  • METHODS: The expressions of HLA class I antigen and CD8 in cervical tissues sampled from patients with cervical cancer, cervical intraepithelial neoplasia (CIN), and chronic cervicitis were detected using SP immunohistochemistry.
  • RESULTS: The positive expression rates of HLA class I antigen in cervical cancer, CIN, and chronic cervicitis were 22.6%, 100.0%, and 100.0%, and the positive expression rates of CD8 were 22.6%, 95.5%, and 100.0%, respectively.
  • The positive rates of HLA class I antigen and CD8 were significantly lower in patients with cervical cancer (P<0.01).
  • Patients with stage I cervical cancer had significantly higher positive rates of HLA class I antigen and CD8 than those with stage II cervical cancer (46.7% vs 0.0%, 46.7% vs 0.0%, both P<0.01).
  • CONCLUSION: The expressions of HLA class I antigen and CD8 are down-regulated or deleted in CIN and cervical cancer, and they may play important roles in the development and progression of CIN and cervical cancer.
  • [MeSH-major] Antigens, CD8 / immunology. Cervical Intraepithelial Neoplasia / immunology. Histocompatibility Antigens Class I / immunology. Uterine Cervical Neoplasms / immunology

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  • (PMID = 19114347.001).
  • [ISSN] 1673-4254
  • [Journal-full-title] Nan fang yi ke da xue xue bao = Journal of Southern Medical University
  • [ISO-abbreviation] Nan Fang Yi Ke Da Xue Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, CD8; 0 / Histocompatibility Antigens Class I
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4. Ivanov S, Kŭrlov A: [The role of the preoperative radiochemotherapy and the role of neoadjuvant chemotherapy before radical Wertheim-Meigs hysterectomy for cervical cancer stage I B - II B]. Akush Ginekol (Sofiia); 2006;45(2):28-31
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The role of the preoperative radiochemotherapy and the role of neoadjuvant chemotherapy before radical Wertheim-Meigs hysterectomy for cervical cancer stage I B - II B].
  • One of the most important prognostic factors for early stages cervical cancers is the tumour size.
  • The aim of our research work was to compare the efficacy of preoperative radiochemotherapy and neoadjuvant intravenous chemotherapy, followed by radical hysterectomy a modo Wertheim-Meigs for stage I B - II B cervical cancer.
  • From 1998 till 2005 we examined 123 patients in stage I B - II B cervical cancer treated by preoperative percutaneous radiotherapy (dosis 45 Gy) plus cisplatin (50 mg/m2) compared with preoperative chemotherapy cisplatin (50 mg/m2), vincristin 1 mg/m2 every 7-10 days for 3 courses.
  • [MeSH-major] Hysterectomy / methods. Neoadjuvant Therapy / methods. Uterine Cervical Neoplasms / therapy

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  • (PMID = 16637300.001).
  • [ISSN] 0324-0959
  • [Journal-full-title] Akusherstvo i ginekologii︠a︡
  • [ISO-abbreviation] Akush Ginekol (Sofiia)
  • [Language] bul
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Bulgaria
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5. Rob L, Pluta M, Strnad P, Hrehorcak M, Chmel R, Skapa P, Robova H: A less radical treatment option to the fertility-sparing radical trachelectomy in patients with stage I cervical cancer. Gynecol Oncol; 2008 Nov;111(2 Suppl):S116-20
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A less radical treatment option to the fertility-sparing radical trachelectomy in patients with stage I cervical cancer.
  • [MeSH-major] Fertility. Gynecologic Surgical Procedures / methods. Uterine Cervical Neoplasms / surgery

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  • (PMID = 18725167.001).
  • [ISSN] 1095-6859
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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6. Gao P, Zhou GY, Yin G, Liu Y, Liu ZY, Zhang J, Hao CY: Lymphatic vessel density as a prognostic indicator for patients with stage I cervical carcinoma. Hum Pathol; 2006 Jun;37(6):719-25
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lymphatic vessel density as a prognostic indicator for patients with stage I cervical carcinoma.
  • However, there are no reports describing the situation in cervical carcinoma.
  • The purpose of this study was to investigate whether LVD could serve as a risk factor for nodal metastasis and recurrence of cervical carcinoma in 147 cases of stage I patients.
  • Other questions were if depth of invasion, proliferation rate, and tumor size could be used as predictive markers for Chinese patients with cervical carcinoma.
  • The results showed that average LVD in cervical carcinoma was statistically associated with inflammatory cell infiltration of carcinoma tissues, but not associated with other pathological parameters.
  • Average LVD of the cases with nodal metastasis or recurrence was significantly higher than the cases without metastasis and recurrence in both stage IA and stage IB cervical carcinomas.
  • The correlation between both depth of invasion and tumor size with nodal metastasis and recurrence of cervical carcinoma was also statistically significant.
  • We concluded that for the patients with stage I cervical carcinoma, increased LVD could serve as a high-risk factor for nodal metastasis and recurrence.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Carcinoma / pathology. Lymph Nodes / pathology. Lymphatic Vessels / pathology. Uterine Cervical Neoplasms / pathology

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  • (PMID = 16733213.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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7. Zivanovic O, Leitao MM, Iasonos A, Jacks LM, Zhou Q, Abu-Rustum NR, Soslow RA, Juretzka MM, Chi DS, Barakat RR, Brennan MF, Hensley ML: Stage-specific outcomes of patients with uterine leiomyosarcoma: a comparison of the international Federation of gynecology and obstetrics and american joint committee on cancer staging systems. J Clin Oncol; 2009 Apr 20;27(12):2066-72
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Stage-specific outcomes of patients with uterine leiomyosarcoma: a comparison of the international Federation of gynecology and obstetrics and american joint committee on cancer staging systems.
  • PURPOSE: Uterine leiomyosarcoma (LMS) is staged by the modified International Federation of Gynecology and Obstetrics (FIGO) staging system for uterine cancer.
  • We aimed to determine whether the American Joint Committee on Cancer (AJCC) soft tissue sarcoma (STS) staging system is more accurate in predicting progression-free survival (PFS) and overall survival (OS).
  • PATIENTS AND METHODS: Patients with uterine LMS who presented at our institution from 1982 to 2005 were staged retrospectively according to a modified FIGO staging system and the AJCC STS staging system.
  • RESULTS: Two hundred nineteen patients had sufficient clinical and pathologic information to be staged under both systems; 132 patients were upstaged using the AJCC staging system, whereas only four were downstaged.
  • Stage-specific PFS and OS rates for stages I, II, and III differed substantially between the two staging systems.
  • Thus, despite the marked stage-specific differences in 5-year PFS and OS rates for stages I, II, and III, both systems had similar concordance indices.
  • CONCLUSION: Estimates of stage-specific PFS and OS for uterine LMS were altered substantially when using the AJCC versus FIGO staging system.
  • Neither the FIGO nor AJCC staging system is ideal for identifying such patients, suggesting a need for a uterine LMS-specific staging system to better target patients for trials of adjuvant therapies.
  • [MeSH-major] Leiomyosarcoma / secondary. Uterine Cervical Neoplasms / pathology

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  • (PMID = 19255317.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3646302
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8. Denewer AD, Setit AE, Hussein OA, Aly OF: Functinal and aesthetic outcome of reconstruction of large oro-facial defects involving the lip after tumor resection. J Egypt Natl Canc Inst; 2006 Mar;18(1):61-6
MedlinePlus Health Information. consumer health - Plastic and Cosmetic Surgery.

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  • BACKGROUND: Squamous cell carcinoma of the head and neck is a challenging disease to both surgeons and radiation oncologists due to proximity of many important anatomical structures.
  • Tumor stage were T2 (43), T3 (56) and T4 (13).
  • AJCC stage grouping was II (T2N0) in 33 patients, stage III (T3N0 or T1-3N1) in 64 cases and stage IV (T4 due to bone erosion or N2) in 15 cases.
  • Bilateral myocutaneous depressor anguli oris (MCDAOF) plus local cervical rotational flap chin defects (n=3).
  • [MeSH-major] Carcinoma, Squamous Cell / surgery. Lip Neoplasms / surgery. Reconstructive Surgical Procedures / methods. Surgical Flaps

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  • (PMID = 17237851.001).
  • [ISSN] 1110-0362
  • [Journal-full-title] Journal of the Egyptian National Cancer Institute
  • [ISO-abbreviation] J Egypt Natl Canc Inst
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
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9. Lajtman E, Mlyncek M, Uharcek P, Matejka M, Urban M: [Assessment of routine surveillance of patients after primary treatment for cervical cancer in stage I. and II.: retrospective analysis]. Ceska Gynekol; 2010 Apr;75(2):135-40
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Assessment of routine surveillance of patients after primary treatment for cervical cancer in stage I. and II.: retrospective analysis].
  • OBJECTIVE: Evaluate the monitoring and diagnosis of recurrence after primary treatment for cervical cancer.
  • METHODS: We retrospectively analyzed 199 patients who have undergone surgical treatment for cervical cancer between 2000 and 2008 at the Faculty Hospital Nitra and they received chemoradioterapy after evaluation of risk factors.
  • CONCLUSION: Regular monitoring of patients after primary treatment of cervical cancer in the rigid intervals and diagnosis of recurrence in the asymptomatic stage does not improve survival compared with symptomatic patients.


10. Ivanov S: [Some new aspects of the treatment for cervical cancer of I B2 stage]. Akush Ginekol (Sofiia); 2006;45(1):24-7
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Some new aspects of the treatment for cervical cancer of I B2 stage].
  • From 2000 till 2005 were retrospectively analyzed 150 cases with cervical cancer stage I B.
  • All tumours were with invasion of outer third of the cervix.
  • [MeSH-major] Adenocarcinoma / surgery. Carcinoma, Squamous Cell / surgery. Uterine Cervical Neoplasms / surgery

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  • (PMID = 16637314.001).
  • [ISSN] 0324-0959
  • [Journal-full-title] Akusherstvo i ginekologii︠a︡
  • [ISO-abbreviation] Akush Ginekol (Sofiia)
  • [Language] bul
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Bulgaria
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11. Carter J, Sonoda Y, Abu-Rustum NR: Reproductive concerns of women treated with radical trachelectomy for cervical cancer. Gynecol Oncol; 2007 Apr;105(1):13-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Reproductive concerns of women treated with radical trachelectomy for cervical cancer.
  • OBJECTIVE: To report the reproductive concerns of women treated for stage I cervical cancer with fertility-preserving surgery.
  • MATERIALS AND METHODS: Newly diagnosed cervical cancer patients undergoing radical trachelectomy were enrolled in this study preoperatively and assessed over time.
  • This pilot study reflects the first preliminary data from an active ongoing study prospectively collecting information over 2 years from newly diagnosed stage I cervical cancer patients undergoing radical trachelectomy.
  • [MeSH-major] Fertility. Uterine Cervical Neoplasms / psychology. Uterine Cervical Neoplasms / surgery

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  • (PMID = 17188344.001).
  • [ISSN] 0090-8258
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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12. Raut CP, Nucci MR, Wang Q, Manola J, Bertagnolli MM, Demetri GD, Morgan JA, Muto MG, Fletcher CD, George S: Predictive value of FIGO and AJCC staging systems in patients with uterine leiomyosarcoma. Eur J Cancer; 2009 Nov;45(16):2818-24
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Predictive value of FIGO and AJCC staging systems in patients with uterine leiomyosarcoma.
  • BACKGROUND: Cancer staging systems aim to identify patient cohorts with different outcomes based on clinically relevant prognostic factors.
  • Uterine leiomyosarcoma (ULMS) is classified using the FIGO staging system developed for epithelial malignancies; other sarcomas use the AJCC staging system.
  • METHODS: We staged 230 ULMS patients by the FIGO and AJCC systems.
  • There were few stage II patients by either system.
  • Using the FIGO system, PFS was better in stage I patients versus stage III or IV patients, and OS was better in stage I patients versus stage IV patients.
  • Using the AJCC system, PFS and OS were better in stage I patients (low grade) versus stage II, III or IV patients, and OS was better in stage III patients versus stage IV patients.
  • Prognosis of patients with serosal involvement (FIGO III) was similar to that of patients with metastases (FIGO IV).
  • This analysis highlights the relevance of certain factors (low grade, serosal involvement) and rarity of others (FIGO stage II, cervical invasion).
  • [MeSH-major] Leiomyosarcoma / pathology. Uterine Neoplasms / pathology

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  • (PMID = 19647426.001).
  • [ISSN] 1879-0852
  • [Journal-full-title] European journal of cancer (Oxford, England : 1990)
  • [ISO-abbreviation] Eur. J. Cancer
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Validation Studies
  • [Publication-country] England
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13. Abu-Rustum NR, Sonoda Y, Black D, Levine DA, Chi DS, Barakat RR: Fertility-sparing radical abdominal trachelectomy for cervical carcinoma: technique and review of the literature. Gynecol Oncol; 2006 Dec;103(3):807-13
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fertility-sparing radical abdominal trachelectomy for cervical carcinoma: technique and review of the literature.
  • OBJECTIVES: Radical trachelectomy has emerged as a reasonable fertility-sparing operation for selected patients with stage I cervical cancer.
  • The purpose of this report is to describe our technique of radical abdominal trachelectomy, a fertility-sparing operation in women with cervical cancer, and review the current literature on this procedure.
  • RESULTS: Between 11/01 and 3/06, we performed a total of 42 fertility-preserving radical trachelectomies with pelvic lymphadenectomy for women with invasive cervical cancer.
  • The characteristics of the 5 adult patients who underwent abdominal radical trachelectomy included stage IB1 disease in all cases, a mean age of 36 years (range, 33-39), and a mean estimated blood loss of 280 ml (range, 50-400); 1 patient with squamous cell carcinoma needed completion radical hysterectomy at the time of trachelectomy due to disease extending into the endometrium, and 1 patient needed postoperative chemoradiation due to a positive parametrial lymph node.
  • The only remaining uterine blood supply in these patients are the utero-ovarian vessels.
  • CONCLUSIONS: Radical abdominal trachelectomy with pelvic lymphadenectomy is a feasible operation for selected women with stage I cervical cancer who desire to preserve reproductive function.
  • Menstruation and reproductive function may be preserved after bilateral uterine vessel ligation.
  • [MeSH-major] Adenocarcinoma / surgery. Fertility. Gynecologic Surgical Procedures / methods. Neoplasms, Squamous Cell / surgery. Uterine Cervical Neoplasms / surgery

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  • [CommentIn] Gynecol Oncol. 2007 Jun;105(3):830-1; author reply 831 [17395253.001]
  • (PMID = 16837027.001).
  • [ISSN] 0090-8258
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 23
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14. Haie-Meder C, Pötter R, Van Limbergen E, Briot E, De Brabandere M, Dimopoulos J, Dumas I, Hellebust TP, Kirisits C, Lang S, Muschitz S, Nevinson J, Nulens A, Petrow P, Wachter-Gerstner N, Gynaecological (GYN) GEC-ESTRO Working Group: Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group (I): concepts and terms in 3D image based 3D treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTV. Radiother Oncol; 2005 Mar;74(3):235-45
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group (I): concepts and terms in 3D image based 3D treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTV.
  • BACKGROUND AND PURPOSE: Brachytherapy (BT) plays a crucial role in the management of invasive cervix cancer from stage I to IV.
  • METHODS: In 2000, GEC-ESTRO decided to support 3D imaging based 3D treatment planning approach in cervix cancer BT with the creation of a Working Group.
  • [MeSH-major] Brachytherapy / methods. Imaging, Three-Dimensional. Uterine Cervical Neoplasms / pathology. Uterine Cervical Neoplasms / radiotherapy

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  • (PMID = 15763303.001).
  • [ISSN] 0167-8140
  • [Journal-full-title] Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
  • [ISO-abbreviation] Radiother Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Ireland
  • [Number-of-references] 36
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15. Guan T, Guo XY, Ye CL, Jiang YH: [Analysis of circulating DNA level in the plasma of cervical cancer patients]. Nan Fang Yi Ke Da Xue Xue Bao; 2008 Aug;28(9):1663-4, 1667
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  • [Title] [Analysis of circulating DNA level in the plasma of cervical cancer patients].
  • OBJECTIVE: To determine the plasma DNA level and investigate its clinicopathological significance in women with cervical cancers.
  • METHODS: Blood samples were collected from 42 cervical cancer patients, 20 patients with cervical intraepithelial neoplasia grade III (CINIII) and 20 healthy women.
  • RESULTS: The mean plasma DNA level in stage I cervical cancer patients was 12.78-/+5.58 ng/ml, significantly higher than that in CINIII patients (8.10-/+3.06 ng/ml) and normal controls (7.60-/+3.87 ng/ml) (P=0.001).
  • The mean DNA level in stage II-III patients was 17.99-/+7.81 ng/ml, significantly higher than that in stage I patients (P=0.02).
  • When the cut-off for diagnosis of cervical cancer was 15.70 ng/ml, the sensitivity, specificity, positive predictive value and negative predictive value were 38.10%, 92.50%, 84.21% and 58.73%, respectively.
  • CONCLUSION: Plasma DNA level is closely related with malignant transformation and development of cervical cancer, and may become a useful means for differential diagnosis of cervical cancer.
  • [MeSH-major] Carcinoma, Squamous Cell / blood. Cervical Intraepithelial Neoplasia / blood. DNA, Neoplasm / blood. Uterine Cervical Neoplasms / blood

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  • (PMID = 18819895.001).
  • [ISSN] 1673-4254
  • [Journal-full-title] Nan fang yi ke da xue xue bao = Journal of Southern Medical University
  • [ISO-abbreviation] Nan Fang Yi Ke Da Xue Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / DNA, Neoplasm
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16. Wu YY, Liang MR, Li LY, Zeng SY: [Analysis of 4223 hospitalized patients with cervical cancer during 1990-2007]. Zhonghua Fu Chan Ke Za Zhi; 2008 Jun;43(6):433-6
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  • [Title] [Analysis of 4223 hospitalized patients with cervical cancer during 1990-2007].
  • OBJECTIVE: To analyze the changes in epidemiology and treatment of hospitalized patients with cervical cancer during 1990-2007.
  • METHODS: Overall, 4648 patients with cervical cancer were diagnosed in our hospital from Jan 1990 to Nov 2007, but only 4223 patients with initial treatment in our hospital were studied retrospectively.
  • Pearson Chi-square test was used to compare the age, stage, histopathologic type and treatment methods between different times. RESULTS:.
  • (1) The mean age of cervical cancer patients gradually decreased over the past 18 years, from 54.4 years during 1990-1999 to 47.2 years during 2000-2007; the proportion of young patients aged < or = 35 years increased from 4.77% (89/1865) during 1990-1999 to 11.75% (277/2358) during 2000-2007. (2) The proportion of patients with cervical cancer (stage I a-II a) increased from 14.
  • 32% (267/1865) during 1990-1999 to 40.75% (961/2358) during 2000-2007, whereas the proportion of patients with cervical cancer (stage II b-IV) decreased from 85.68% (1598/1865) during 1990-1999 to 59.25% (1397/2358) during 2000-2007. (3) There was no significant change in histopathologic type of cervical cancer, and squamous cell carcinoma of cervix remained the main type of cervical cancer. (4) The treatment pattern of cervical cancer changed significantly: radiotherapy was the main method (75.28%) for cervical cancer during 1990-1999, but during 2000-2007, it was replaced by concurrent chemoradiotherapy (35.79%).
  • CONCLUSIONS: The proportion of young women with cervical cancer was increased during 1990-2007, and at the same period early stage cervical cancer increased, but late stage cervical cancer decreased.
  • It is obvious that chemotherapy has become the important therapy in cervical cancer.
  • [MeSH-major] Adenocarcinoma / epidemiology. Adenocarcinoma / pathology. Carcinoma, Squamous Cell. Uterine Cervical Neoplasms
  • [MeSH-minor] Adult. Age Distribution. Aged. Aged, 80 and over. Antineoplastic Protocols. Cervix Uteri / pathology. Combined Modality Therapy. Female. Humans. Incidence. Inpatients. Middle Aged. Neoplasm Staging. Radiotherapy. Retrospective Studies


17. Liao XB, Mao YP, Liu LZ, Tang LL, Sun Y, Wang Y, Lin AH, Cui CY, Li L, Ma J: How does magnetic resonance imaging influence staging according to AJCC staging system for nasopharyngeal carcinoma compared with computed tomography? Int J Radiat Oncol Biol Phys; 2008 Dec 1;72(5):1368-77
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  • [Title] How does magnetic resonance imaging influence staging according to AJCC staging system for nasopharyngeal carcinoma compared with computed tomography?
  • PURPOSE: To analyze the degree and pattern of influence of magnetic resonance imaging (MRI) on staging according to the 6th edition of the American Joint Committee on Cancer staging system compared with computed tomography (CT).
  • METHODS AND MATERIALS: The MRI and CT scans and medical records of 420 consecutive patients with newly diagnosed nasopharyngeal carcinoma (NPC) were analyzed retrospectively.
  • The tumors of all patients were staged according to the 6th edition of the American Joint Committee on Cancer staging system.
  • The incidence of cervical lymph node metastasis and lymph node metastasis at each level was similar according to CT and MRI.
  • MRI resulted in changes in 49.8% of T stage cases, 10.7% of N stage cases, and 38.6% of clinical stage cases.
  • The use of MRI caused dramatic changes in the results of the T stage and clinical staging and should be preferred to CT in staging NPC.

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  • (PMID = 18455329.001).
  • [ISSN] 1879-355X
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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18. Shi HR, Wu QH, Suo ZH, Nesland JM: [Correlation between methylation of 5'-CpG islands and inactivation of FHIT gene in cervical cancer]. Ai Zheng; 2005 Jan;24(1):7-11
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Correlation between methylation of 5'-CpG islands and inactivation of FHIT gene in cervical cancer].
  • This study was designed to explore relationship of methylation of 5'-CpG islands with inactivation of FHIT gene in cervical cancer.
  • METHODS: Methylation of 5'-CpG islands in 10 normal cervical squamous epithelial tissues, and 40 cervical cancer tissues was detected with methylation specific polymerase chain reaction (MSP), protein expression of FHIT was detected with immunohistochemistry, and their correlations with clinicopathologic features of cervical cancer were statistically analyzed. RESULTS:.
  • (1) The 5'-CpG islands methylation rate of FHIT gene in cervical cancer tissues was 40.0% (16/40), while no methylation of FHIT gene was found in normal cervical tissues. (2) The methylation rates of FHIT gene in cervical cancer of stage I was 14.3% (2/14), significantly lower than that in cervical cancer of stage II (56.5%, 13/23) (P<0.05). (3) Expression of FHIT protein in cervical cancer was 33.0% (12/40), significantly lower than that in normal cervical tissue (100%, 10/10) (P<0.05).
  • CONCLUSION: The 5'-CpG islands methylation may play an important role in inactivation of FHIT gene, and may be related with tumorigenesis of cervical cancer.
  • [MeSH-major] Acid Anhydride Hydrolases / biosynthesis. CpG Islands / genetics. DNA Methylation. Gene Silencing. Neoplasm Proteins / biosynthesis. Uterine Cervical Neoplasms / genetics
  • [MeSH-minor] Adult. Aged. Carcinoma, Squamous Cell / genetics. Carcinoma, Squamous Cell / metabolism. Carcinoma, Squamous Cell / pathology. Female. Genes, Tumor Suppressor. Humans. Middle Aged. Neoplasm Staging

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  • (PMID = 15642192.001).
  • [Journal-full-title] Ai zheng = Aizheng = Chinese journal of cancer
  • [ISO-abbreviation] Ai Zheng
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Neoplasm Proteins; 0 / fragile histidine triad protein; EC 3.6.- / Acid Anhydride Hydrolases
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19. Gao JM, Zeng YX, Cui NJ, Lu TX, Zhao C, Xia YF, Ma J, Xie FY: [Staging 915 cases of nasopharyngeal carcinoma after simple radical radiotherapy (Part II)--Checkout of AJCC/UICC staging system (1997)]. Ai Zheng; 2006 Mar;25(3):257-63
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  • [Title] [Staging 915 cases of nasopharyngeal carcinoma after simple radical radiotherapy (Part II)--Checkout of AJCC/UICC staging system (1997)].
  • BACKGROUND & OBJECTIVE: On the basis of our previous research, this study was to validate the rationality of AJCC/UICC staging system (1997) of nasopharyngeal carcinoma (NPC), and to provide some suggestions.
  • METHODS: Survival data of 915 NPC patients, received radical radiotherapy alone in Cancer Center of Sun Yat-sen University from Jan.
  • RESULTS: Cox regression analysis showed that the 5-year survival rate of the 915 patients was significantly correlated to their age and tumor stage classified according to AJCC/UICC (1997) staging system; while that of the 803 patients no more than 60 years old was only significantly correlated to tumor stage.
  • Life table analysis validated that the tumor stage classified according to AJCC/UICC staging system can roughly predict the prognosis, but the differences between stage I and IIa, or IVa and IVb were not significant.
  • Kaplan-Meier analysis showed no significant differences of survival rate between stage T1 and T2a, or T3 and T4 when adjusted by N classification, and between stage N2 and N3a, or N3a and N3b when adjusted by T classification.
  • Therefore, we adjusted stage T2a to T1, stage N1 with inferior cervical nodes metastasis to N2, combined stage N3a and N3b to N3, adjusted stage IIa to I, stage IIb to II, and stage IVb to IVa.
  • CONCLUSION: Taking the impact of age on the prognosis and the interaction between T stage and N stage into consideration, the above modifications should be included when renewing the AJCC/UICC staging system (1997).

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  • (PMID = 16536975.001).
  • [Journal-full-title] Ai zheng = Aizheng = Chinese journal of cancer
  • [ISO-abbreviation] Ai Zheng
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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20. Rogers LJ, Luesley DM: Stage IA2 cervical carcinoma: how much treatment is enough? Int J Gynecol Cancer; 2009 Dec;19(9):1620-4
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Stage IA2 cervical carcinoma: how much treatment is enough?
  • OBJECTIVE: The current guidance for the management of women with stage IA2 cervical carcinoma is that whatever the primary surgical intervention, pelvic lymphadenectomy should be included.
  • The role of lymphadenectomy in the management of cervical carcinoma remains somewhat confused, as the procedure has not been proven to be therapeutic, although it is claimed that the information gained is valuable in determining the need for adjuvant therapy.
  • For lymphadenectomy to have clinical utility in the care of women with stage IA2 cervical carcinoma, a sufficiently high incidence of node positivity would be required to justify the morbidity of the procedure for the whole group.
  • The objective of this paper was to establish the incidence of pelvic lymph node positivity in stage IA2 cervical carcinoma.
  • METHODS: A PubMed search using the words "stage IA2 cervical carcinoma," "microinvasive cervical carcinoma," "stage IA cervical carcinoma," "stage I cervical carcinoma," and "lymphadenectomy in cervical carcinoma" was performed; the articles were divided into those that adhered to the International Federation of Gynecology and Obstetrics (FIGO) definition of a stage IA2 tumor and those that did not.
  • Sentinel node studies were not included, as this procedure does not form part of the FIGO guidelines.
  • RESULTS: Studies adhering to the FIGO definition showed a 0.5% incidence of lymph node metastases in stage IA2 cervical carcinomas, which is not as high as was previously believed (7.3%).
  • [MeSH-major] Carcinoma / epidemiology. Carcinoma / therapy. Lymph Node Excision / utilization. Uterine Cervical Neoplasms / epidemiology. Uterine Cervical Neoplasms / therapy

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  • (PMID = 19994472.001).
  • [ISSN] 1525-1438
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 23
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21. Nezhat F, Mahdavi A, Nagarsheth NP: Total laparoscopic radical hysterectomy and pelvic lymphadenectomy using harmonic shears. J Minim Invasive Gynecol; 2006 Jan-Feb;13(1):20-5
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

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  • STUDY OBJECTIVE: To describe the feasibility and outcome of total laparoscopic radical hysterectomy with or without pelvic lymphadenectomy for patients with stage I cervical cancer or severe pelvic endometriosis using harmonic shears as the sole instrument for dissection, division, and maintenance of hemostasis of all major surgical pedicles.
  • PATIENTS: Seven patients who underwent total laparoscopic radical hysterectomy using harmonic shears for International Federation of Gynecology and Obstetrics stage IA2 to IB1 cervical cancer and pelvic endometriosis at our institution or affiliate hospital from January 2004 through February 2005.
  • MEASUREMENTS AND MAIN RESULTS: Pelvic lymphadenectomy was performed in all cancer cases.
  • Mean pelvic node count was 27.8 (range 24-34) for cancer cases.
  • [MeSH-major] Endometriosis / surgery. Hysterectomy / methods. Laparoscopy / methods. Lymph Node Excision / methods. Uterine Cervical Neoplasms / surgery
  • [MeSH-minor] Adenocarcinoma / pathology. Adenocarcinoma / surgery. Adult. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Female. Humans. Middle Aged. Neoplasm Staging. Pelvis. Retrospective Studies. Treatment Outcome

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  • [CommentIn] J Minim Invasive Gynecol. 2006 Sep-Oct;13(5):488-9; author reply 489 [16962541.001]
  • (PMID = 16431319.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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22. Kim YT, Kim SW, Hyung WJ, Lee SJ, Nam EJ, Lee WJ: Robotic radical hysterectomy with pelvic lymphadenectomy for cervical carcinoma: a pilot study. Gynecol Oncol; 2008 Feb;108(2):312-6
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

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  • [Title] Robotic radical hysterectomy with pelvic lymphadenectomy for cervical carcinoma: a pilot study.
  • OBJECTIVES: The purpose of this study was to evaluate the feasibility and surgical outcome of robotic radical hysterectomy with pelvic lymphadenectomy for stage I cervical carcinoma using the da Vinci surgical system.
  • METHODS: A retrospective clinical review was performed of ten patients with FIGO stage IA2-IB1 cervical carcinoma who underwent a total robotic approach for definitive surgical treatment.
  • CONCLUSIONS: Robotic radical hysterectomy with pelvic lymphadenectomy for selected patients with stage IB1 cervical cancer is feasible, promising and related with a low morbidity in this pilot study.
  • [MeSH-major] Hysterectomy / methods. Lymph Node Excision / methods. Robotics / methods. Uterine Cervical Neoplasms / surgery

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  • (PMID = 18035405.001).
  • [ISSN] 1095-6859
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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23. Alrawi SJ, Winston J, Tan D, Gibbs J, Loree TR, Hicks W, Rigual N, Lorè JM Jr: Primary adenocarcinoma of cervical esophagus. J Exp Clin Cancer Res; 2005 Jun;24(2):325-30
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  • [Title] Primary adenocarcinoma of cervical esophagus.
  • Most upper esophageal malignancies are squamous cell carcinomas, rarely adenocarcinomas arising from Barrett's esophagus and very rarely adenocarcinomas from heterotopic gastric mucosa without evidence of Barrett's especially in the cervical part of the esophagus.
  • We report a case of adenocarcinoma of the polypoid type in the upper esophagus (cervical esophagus) arising from ectopic gastric mucosa, in a 60 year-old man who presented with progressive dysphagia.
  • Accurate diagnosis by esophagogram revealed a large mass in the cervical esophagus; CAT scan showed intraluminal mass at the level of thoracic inlet, esophagogastroscopy showed a fleshy polyp (3.2cm x 3.0cm) at 20 cm from the incisors with a biopsy confirming moderately differentiated adenocarcinoma with no evidence of Barrett's esophagus.
  • Through a left cervical approach and resection of medial third of clavicle, the tumor was removed by partial esophagectomy followed by lymph node dissection, and proved to be T1NOMO, stage I (AJCC staging 6th ed.).

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  • (PMID = 16110768.001).
  • [ISSN] 0392-9078
  • [Journal-full-title] Journal of experimental & clinical cancer research : CR
  • [ISO-abbreviation] J. Exp. Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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24. Czygier M, Ławicki S, Gacuta-Szumarska E, Bedkowska E, Szmitkowski M: [The plasma level of sL-selectin, myeloperoxidase (MPO) and granulocyte-colony stimulating factor (G-CSF) in gynecological cancer patients]. Przegl Lek; 2010;67(3):184-6
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

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  • [Title] [The plasma level of sL-selectin, myeloperoxidase (MPO) and granulocyte-colony stimulating factor (G-CSF) in gynecological cancer patients].
  • The purpose of this investigation was to evaluate in the plasma of breast cancer patients the level of adhesion molecule--sL-selectin, as a measure of maturate granulocyte activity and MPO--enzyme of granulocyte, responsible for the cytotoxicity.
  • We tested 17 patients with I stage endometrial cancer and 19 patients with I stage cervical cancer.
  • In gynecological cancer patients sL-selectin concentration was decreased, but myeloperoxidase concentration increased in comparison to the control group.
  • G-CSF level in group with endometrial cancer was similar to the control group, but in group with cervical cancer was significantly lower.
  • These results suggest that ability of granulocyte binding to cancer cells is decreased but cytotoxicity is increased, at lack of stimulation by of G-CSF.
  • [MeSH-major] Biomarkers, Tumor / blood. Endometrial Neoplasms / blood. Granulocyte Colony-Stimulating Factor / blood. L-Selectin / blood. Peroxidase / blood. Uterine Cervical Neoplasms / blood

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  • (PMID = 20687382.001).
  • [ISSN] 0033-2240
  • [Journal-full-title] Przegla̧d lekarski
  • [ISO-abbreviation] Prz. Lek.
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 126880-86-2 / L-Selectin; 143011-72-7 / Granulocyte Colony-Stimulating Factor; EC 1.11.1.7 / Peroxidase
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25. Li B, Zhang QF, Lin XY, Chen LL, Ouyang L, Zhang SL: [Expression and significance of elastin and fibulin-5 in anterior vaginal tissue of women with pelvic organ prolapse]. Zhonghua Fu Chan Ke Za Zhi; 2009 Jul;44(7):514-7
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  • Meanwhile, 18 cases with early cervical cancer at stage of I b were treated by total hysterectomy and bilateral salpingo-oophorectomy, their anterior vaginal tissues were selected as controls.
  • [MeSH-minor] Aged. Carcinoma, Squamous Cell / metabolism. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Connective Tissue / metabolism. Female. Humans. Immunohistochemistry. Menopause. Middle Aged. Severity of Illness Index. Uterine Cervical Neoplasms / metabolism. Uterine Cervical Neoplasms / pathology. Uterine Cervical Neoplasms / surgery

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  • (PMID = 19957551.001).
  • [ISSN] 0529-567X
  • [Journal-full-title] Zhonghua fu chan ke za zhi
  • [ISO-abbreviation] Zhonghua Fu Chan Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Extracellular Matrix Proteins; 0 / FBLN5 protein, human; 9007-58-3 / Elastin
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26. Carter J, Sonoda Y, Chi DS, Raviv L, Abu-Rustum NR: Radical trachelectomy for cervical cancer: postoperative physical and emotional adjustment concerns. Gynecol Oncol; 2008 Oct;111(1):151-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radical trachelectomy for cervical cancer: postoperative physical and emotional adjustment concerns.
  • OBJECTIVE: To investigate the incidence of cervical stenosis and related emotional and sexual adjustment concerns in women treated with radical trachelectomy.
  • METHODS: Prospective data of 30 stage I cervical cancer patients enrolled in an ongoing study were evaluated in combination with a medical chart review.
  • RESULTS: Eight patients (27%) did not have any stenosis of the neo-cervix postoperatively; 10 (33%) had clinically notable stenosis not requiring neo-cervical dilation to allow adequate sampling; moreover, 12 (40%) had sufficient stenosis requiring a neo-cervical dilation procedure, which proved to be safe and useful.
  • Office cervical dilation is a simple procedure, which is helpful in the management of neo-cervical stenosis.
  • [MeSH-major] Affective Symptoms / etiology. Gynecologic Surgical Procedures / psychology. Uterine Cervical Neoplasms / psychology. Uterine Cervical Neoplasms / surgery


27. Wang X, Xie FY, Han F, Hu WH, Li JS, Xu HM: [Tonsillar carcinoma: analyses of the therapy and prognostic factors]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2009 Oct;44(10):848-52

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Tonsillar carcinoma: analyses of the therapy and prognostic factors].
  • OBJECTIVE: To retrospectively analyze the therapeutic effect on patients with tonsillar carcinoma and factors affecting their prognosis.
  • METHODS: Clinical data of 61 patients pathologically confirmed with tonsillar carcinoma without distant metastasis were analyzed.
  • All the patients were treated in Cancer Center of Sun Yat-sen University from April 1997 to April 2008.
  • There were 2 patients with undifferentiated carcinoma, 26 with poorly differentiated squamous cell carcinoma and 33 with median-well differentiated squamous cell carcinoma.
  • According to the AJCC 2002 staging criteria for head-neck cancers, there were 9 staged I cases, 7 staged II cases, 23 staged III cases and 22 staged IV cases.
  • According to T stages, the 5-year survival rates of stage T1-T4 cases were 91.8%, 46.8%, 29.1%, 0% respectively (chi(2) = 30.168, P < 0.001).
  • Multivariate analysis demonstrated that T stage, therapeutic effect of primary site and cervical metastatic lymph node were the independent prognostic factors (P < 0.05).
  • CONCLUSIONS: T stage, the therapeutic effect of primary site and cervical metastatic lymph node were the independent prognostic factors.
  • [MeSH-major] Carcinoma, Squamous Cell / therapy. Tonsillar Neoplasms / therapy

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  • (PMID = 20079056.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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28. Lin ZX, Yang ZN, Zhan YZ, Xie WJ, Li GW, Feng HT: [Application study of the 2008 staging system of nasopharyngeal carcinoma]. Ai Zheng; 2009 Oct;28(10):1029-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Application study of the 2008 staging system of nasopharyngeal carcinoma].
  • BACKGROUND AND OBJECTIVE: The 2008 staging system of nasopharyngeal carcinoma (NPC) was generated based on the NPC 92 and AJCC staging system.
  • This study was to evaluate its rationality as well as compare the stage distribution among the 3 staging systems, by using of MRI imaging.
  • RESULTS: Involvement of oropharynx, nasopharynx, soft palatine, prevertebral muscles, post-styloid space, intracranial, orbit, 1st and/or 2nd cervical body are 100% accompanied with other same or more advanced T-stage classifications.
  • Cervical lymph node metastasis (LNM) accounted for 76.3%.
  • Advanced stage accounted for 81.4%, 78.5% and 75.7% in 2008, UICC and NPC 92 staging system, respectively, without statistic difference.
  • CONCLUSION: Nasal involvement criteria and T-stage classification of the medial pterygoid muscle defined by NPC 2008 staging system seems reasonable.
  • Stage distribution is also similar to the other 2 systems.

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  • (PMID = 19799809.001).
  • [Journal-full-title] Ai zheng = Aizheng = Chinese journal of cancer
  • [ISO-abbreviation] Ai Zheng
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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29. Oplatek A, Ozer E, Agrawal A, Bapna S, Schuller DE: Patterns of recurrence and survival of head and neck adenoid cystic carcinoma after definitive resection. Laryngoscope; 2010 Jan;120(1):65-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Patterns of recurrence and survival of head and neck adenoid cystic carcinoma after definitive resection.
  • OBJECTIVES/HYPOTHESIS: To determine factors impacting recurrence and long-term survival of adenoid cystic carcinoma (ACC) of the head and neck after definitive resection.
  • American Joint Committee on Cancer (AJCC) tumor stage and N stage were independent predictors of survival on multivariate analysis.
  • Mean overall survival (P = .001) and time to recurrence (P = .006) were lower for patients with cervical lymph node positive disease (N+).
  • The presence of lymphovascular invasion predicted recurrence on multivariate analysis (P = .002), with advanced tumor stage predicting early (<or=36 months) recurrence (P = .013).
  • CONCLUSIONS: Clinicopathological variables including AJCC tumor stage, tumor site, presence of N+ disease, and lymphovascular invasion may be used as prognostic factors in predicting survival and recurrence after a definitive resection of ACC of the head and neck.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Carcinoma, Adenoid Cystic / surgery. Head and Neck Neoplasms / pathology. Head and Neck Neoplasms / surgery

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  • (PMID = 19877226.001).
  • [ISSN] 1531-4995
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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30. Sun Y, Mao YP, Ma J, Huang Y, Tang LL, Wang Y, Liu LZ, Lu TX: [Influences of magnetic resonance imaging on the staging system of nasopharyngeal carcinoma]. Ai Zheng; 2007 Feb;26(2):158-63
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Influences of magnetic resonance imaging on the staging system of nasopharyngeal carcinoma].
  • BACKGROUND & OBJECTIVE: The value of magnetic resonance imaging (MRI) in assessing the extension of nasopharyngeal carcinoma (NPC) is better than that of computed tomography (CT).
  • This study was to analyze the influences of MRI on the Chinese '92 staging system and the 6(th) edition International Union Against Cancer/American Joint Committee on Cancer (UICC/AJCC) staging system of NPC.
  • 2004, 250 naive patients with histologically diagnosed NPC, with no metastasis, received both enhanced spiral CT and MRI scans of the nasopharynx and cervix.
  • Clinical stage was classified according to the Chinese '92 staging system and the 6(th) edition UICC/AJCC staging system, respectively, based on both CT/MRI imaging data and clinical information.
  • RESULTS: MRI was better than CT in detecting the invasion of NPC in the extra-nasopharyngeal cavity (the oropharyrnx, nasal cavity, and parapharyngeal spatium), retropharyngeal lymph node, base of skull, paranasal sinuses, intracranial cavernous sinus, infratemporal fossa, and cervical vertebra.
  • There was no statistical difference between CT and MRI in detecting cervical lymph node metastasis.
  • Compared with CT, MRI made changes in 32.0% of T stage (including 26.0% up-staging and 6.0% down-staging), 11.6% of N stage (6.4% up-staging and 5.2% down-staging), and 30.4% of clinical stage (24.0% up-staging and 6.4% down-staging) for the Chinese '92 staging system, while made changes in 39.6% of T stage (36.0% up-staging and 3.6% down-staging), 9.2% of N stage (5.6% up-staging and 3.6% down-staging), and 37.6% of clinical stage (33.6% up-staging and 4.0% down-staging) for the 6(th) edition UICC/AJCC staging system.
  • CONCLUSIONS: Compared with CT, MRI has a remarkable advantage in detecting the primary tumor extension of NPC, but has no advantage in detecting cervical lymph node metastasis.

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  • (PMID = 17298745.001).
  • [Journal-full-title] Ai zheng = Aizheng = Chinese journal of cancer
  • [ISO-abbreviation] Ai Zheng
  • [Language] chi
  • [Publication-type] Comparative Study; English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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31. Shi HR, Yang XF, Wen JG: [Urodynamic study of lower urinary tract function after radical hysterectomy in postoperative women of cervical cancer]. Zhonghua Fu Chan Ke Za Zhi; 2007 Dec;42(12):815-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Urodynamic study of lower urinary tract function after radical hysterectomy in postoperative women of cervical cancer].
  • OBJECTIVE: To investigate the characteristics of the preoperative and postoperative urodynamical parameters of women with uterine cervical carcinoma after radical hysterectomies.
  • METHODS: Forty-six women had uterine cervical carcinoma at stage I b or II a Complete pre- and postoperative urodynamic follow-ups were conducted for each patient.
  • [MeSH-major] Hysterectomy / adverse effects. Postoperative Complications. Postoperative Period. Urinary Bladder / surgery. Urinary Incontinence, Stress / etiology. Uterine Cervical Neoplasms / surgery






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