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1. Abdel-Halim SH, Shehata AM, El-Shahat MF: Removal of cadmium ions from industrial waste water plants around Cairo. Bull Environ Contam Toxicol; 2005 Jan;74(1):78-85
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  • [Title] Removal of cadmium ions from industrial waste water plants around Cairo.
  • [MeSH-major] Cadmium / isolation & purification. Waste Disposal, Fluid / methods. Water Pollutants / isolation & purification. Water Purification / methods
  • [MeSH-minor] Egypt. Industrial Waste

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  • (PMID = 15768502.001).
  • [ISSN] 0007-4861
  • [Journal-full-title] Bulletin of environmental contamination and toxicology
  • [ISO-abbreviation] Bull Environ Contam Toxicol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Industrial Waste; 0 / Water Pollutants; 00BH33GNGH / Cadmium
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2. Yan L, DeMars LC: Effects of dietary fat on spontaneous metastasis of Lewis lung carcinoma in mice. Clin Exp Metastasis; 2010 Dec;27(8):581-90
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  • Three-week old male C57BL/6 mice were fed the AIN-93G diet or a 45% fat diet (% kcal.) for 7 weeks before they were subcutaneously injected with 2.5 × 10⁵ viable carcinoma cells.
  • The high-fat diet significantly increased body weight and abdominal adipose weight compared to the AIN-93G diet.
  • Feeding mice the 45% fat diet resulted in a two-fold increase in the number of lung metastases (P < 0.05), a 35% increase in tumor cross-sectional area, and a 50% increase in tumor volume compared to mice fed the AIN-93G diet.
  • There were no differences in plasma concentrations of TIMP-1, IL-1β, VEGF and MCP-1 in non-tumor-bearing mice fed the AIN-93G diet or the high-fat diet, but significant increases in these cytokines in tumor-bearing mice fed the AIN-93G diet compared to the non-tumor-bearing mice fed the same diet (P < 0.05 for each comparison).
  • Further significant increases in these cytokines in tumor-bearing mice fed the 45% fat diet compared to the same tumor-bearing mice fed the AIN-93G diet (P < 0.05 for each comparison).
  • The high-fat diet significantly increased plasma leptin and significantly decreased plasma adiponectin compared to the AIN-93G diet in both non-tumor-bearing and tumor-bearing mice.

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  • (PMID = 20697780.001).
  • [ISSN] 1573-7276
  • [Journal-full-title] Clinical & experimental metastasis
  • [ISO-abbreviation] Clin. Exp. Metastasis
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Cytokines; 0 / Dietary Fats
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3. Mohamed SK, Ibraheem AS, Abdelraheem MG: Preoperative intravenous dexamethasone combined with glossopharyngeal nerve block: role in pediatric postoperative analgesia following tonsillectomy. Eur Arch Otorhinolaryngol; 2009 Nov;266(11):1815-9
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  • [Title] Preoperative intravenous dexamethasone combined with glossopharyngeal nerve block: role in pediatric postoperative analgesia following tonsillectomy.
  • Tonsillectomy is one of the most frequently performed ambulatory surgical procedures in children (Litman et al. in Anesth Analg 78:478-481, 1994).
  • Several techniques have been described for alleviation of pain (Ginstrom et al. in Acta Otolaryngol 125:972-975, 2005).
  • the objective of this study determination of the postoperative analgesic efficacy of the pre-surgical intravenous administration of dexamethasone together with glossopharyngeal nerve block (GNB) in children undergoing tonsillectomy.
  • Prospective double blind randomized control study using both pre-operative injection of 0.5 mg/kg dexamethasone iv and 3 ml of 0.5% bupivacaine local injection for bilateral glossopharyngeal nerve block.
  • Patients in group B had significantly less visual analogue scale values, longer absolute analgesia time, lesser swallowing difficulty and they were discharged earlier from the hospital when compared to patients in both groups D and G.
  • Using both pre-operative dexamethasone IV injection with GNB has reduced postoperative pain and morbidity to a great extent than using either alone.
  • [MeSH-major] Dexamethasone / administration & dosage. Glossopharyngeal Nerve. Glucocorticoids / administration & dosage. Nerve Block / methods. Pain, Postoperative / prevention & control. Tonsillectomy / adverse effects
  • [MeSH-minor] Child. Child, Preschool. Double-Blind Method. Drug Administration Schedule. Female. Humans. Injections, Intravenous. Male. Preoperative Care. Treatment Outcome

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  • (PMID = 19263066.001).
  • [ISSN] 1434-4726
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Glucocorticoids; 7S5I7G3JQL / Dexamethasone
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4. Devaraj B, Cosman BC: Expectant management of anal squamous dysplasia in patients with HIV. Dis Colon Rectum; 2006 Jan;49(1):36-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expectant management of anal squamous dysplasia in patients with HIV.
  • PURPOSE: Anal squamous dysplasia is commonly found in patients with HIV infection.
  • This study reviews a series of patients with HIV and an abnormal anal examination who had squamous dysplasia and who have been followed with physical examination alone and with repeat biopsies as necessary for new or suspicious lesions.
  • METHODS: We reviewed the charts of 40 HIV-positive men who had squamous dysplasia of the anal canal and anal margin, focusing on history, physical findings, histologic diagnosis, and the occurrence of invasive squamous-cell carcinoma.
  • RESULTS: Forty HIV-positive men (mean age, 39 years) were followed for anal squamous dysplasia.
  • Biopsies revealed dysplasia, which was usually multifocal.
  • The grade of dysplasia varied, but 28 of 40 patients had at least one area of severe dysplasia.
  • CONCLUSIONS: Extensive excision for dysplasia in the context of HIV confers high morbidity and questionable benefit, and other treatments are of uncertain value.
  • Physical examination surveillance for invasive carcinoma may be acceptable for following patients with HIV and biopsy-proven squamous dysplasia.
  • [MeSH-major] Anus Neoplasms / surgery. Carcinoma, Squamous Cell / surgery. Colectomy / methods. Decision Making. HIV / immunology. HIV Antibodies / immunology. HIV Infections / complications

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  • [CommentIn] Dis Colon Rectum. 2006 Oct;49(10):1648-9; author reply 1649-50 [16972138.001]
  • (PMID = 16283561.001).
  • [ISSN] 0012-3706
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / HIV Antibodies
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5. Elgazwy AS, Ismail NS, Elzahabi HS: A convenient synthesis and molecular modeling study of novel purine and pyrimidine derivatives as CDK2/cyclin A3 inhibitors. Bioorg Med Chem; 2010 Nov 1;18(21):7639-50
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  • [Title] A convenient synthesis and molecular modeling study of novel purine and pyrimidine derivatives as CDK2/cyclin A3 inhibitors.
  • A series of novel purine and pyrimidine derivatives were prepared and biologically evaluated for their in vitro anti-CDK2/cyclin A3 and antitumor activities in Ehrlich ascites carcinoma (EAC) cell based assay.
  • The novel purine derivatives 13a,b demonstrated potent inhibitor activities with IC(50) values of 14±9 and 13±9 μM, respectively.
  • Additionally, compound 15a showed the highest potency (IC(50)=10±6 μM) in EAC cell based assay.
  • Molecular modeling study, including fitting to a 3D-pharmacophore model and their docking into cyclin dependant kinase2 (CDK2) active site showed high fit values and docking scores.
  • [MeSH-major] Antineoplastic Agents / chemical synthesis. Cyclin-Dependent Kinase 2 / antagonists & inhibitors. Models, Molecular. Protein Kinase Inhibitors / chemical synthesis. Purines / chemistry. Pyrimidines / chemistry. Sulfonamides / chemical synthesis
  • [MeSH-minor] Animals. Binding Sites. Catalytic Domain. Cell Line, Tumor. Computer Simulation. Mice. Structure-Activity Relationship

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  • [Copyright] Copyright © 2010 Elsevier Ltd. All rights reserved.
  • (PMID = 20851615.001).
  • [ISSN] 1464-3391
  • [Journal-full-title] Bioorganic & medicinal chemistry
  • [ISO-abbreviation] Bioorg. Med. Chem.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / N-(((1,2-dicyano-2-(((4-methoxyphenyl)methylene)amino)vinyl)amino)carbonyl)-4-methylbenzenesulfonamide; 0 / Protein Kinase Inhibitors; 0 / Purines; 0 / Pyrimidines; 0 / Sulfonamides; EC 2.7.11.22 / Cyclin-Dependent Kinase 2
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6. Abdel-Salam Z, Nammas W: The combined pharmacological stress echocardiography protocol for predicting improvement of global left ventricular systolic function after revascularisation. Heart Lung Circ; 2010 Feb;19(2):81-9
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  • [Title] The combined pharmacological stress echocardiography protocol for predicting improvement of global left ventricular systolic function after revascularisation.
  • BACKGROUND: We compared the prognostic power of three pharmacological stress echocardiography protocols for predicting improvement of global left ventricular systolic function following revascularisation.
  • METHODS: We enrolled 100 consecutive patients with significant coronary stenosis/occlusion and regional dys-synergy in the affected artery territory.
  • Patients underwent assessment of regional and global left ventricular systolic function.
  • They underwent then three pharmacological stress echocardiography protocols: low dose dobutamine, infra-low dose dipyridamole, combined protocol.
  • All patients underwent coronary revascularisation.
  • Echocardiography was repeated 8 weeks later.
  • Predicted function improvement by the three protocols was compared with actual improvement.
  • RESULTS: The combined protocol was more sensitive to predict systolic function improvement after revascularisation, but less specific, the diagnostic accuracy was similar among the three protocols.
  • A cutoff value of 6 viable segments best predicted global function improvement with the combined protocol.
  • CONCLUSIONS: The combined protocol has a higher sensitivity but lower specificity to predict global left ventricular systolic function improvement after revascularisation, as compared to the other two protocols.
  • [MeSH-major] Angioplasty, Balloon, Coronary. Coronary Artery Bypass. Coronary Stenosis / therapy. Coronary Stenosis / ultrasonography. Echocardiography, Stress. Ventricular Dysfunction, Left / ultrasonography
  • [MeSH-minor] Cardiotonic Agents. Dipyridamole. Dobutamine. Female. Health Status Indicators. Humans. Male. Middle Aged. Predictive Value of Tests. Prognosis. Prospective Studies. Sensitivity and Specificity. Systole. Time Factors. Vasodilator Agents. Ventricular Function, Left

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  • [Copyright] Copyright (c) 2009 Australasian Society of Cardiac and Thoracic Surgeons and the Cardiac Society of Australia and New Zealand. Published by Elsevier B.V. All rights reserved.
  • (PMID = 19914129.001).
  • [ISSN] 1444-2892
  • [Journal-full-title] Heart, lung & circulation
  • [ISO-abbreviation] Heart Lung Circ
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Cardiotonic Agents; 0 / Vasodilator Agents; 3S12J47372 / Dobutamine; 64ALC7F90C / Dipyridamole
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7. Shehatah A, Rabie MA, Al-Shahry A: Prevalence and correlates of depressive disorders in elderly with type 2 diabetes in primary health care settings. J Affect Disord; 2010 Jun;123(1-3):197-201
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  • Depressive disorder was defined as a BDI-II score >14 and/or use of antidepressant medication.
  • The prevalence of depressive disorder (as defined by BDI-II>14 and/or antidepressant use) in participants with type 2 diabetes was significantly higher than that of age- and sex-adjusted non diabetic participants (32.1 vs. 16.0%, P<0.0001).
  • [MeSH-major] Depressive Disorder, Major / epidemiology. Depressive Disorder, Major / psychology. Diabetes Mellitus, Type 2 / epidemiology. Diabetes Mellitus, Type 2 / psychology

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  • [Copyright] Crown Copyright 2009. Published by Elsevier B.V. All rights reserved.
  • (PMID = 19804911.001).
  • [ISSN] 1573-2517
  • [Journal-full-title] Journal of affective disorders
  • [ISO-abbreviation] J Affect Disord
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antidepressive Agents
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8. Afandi B, Ahmad S, Saadi H, Elkhumaidi S, Karkoukli MA, Kelly B, Assaf H, Matear D: Audit of a diabetes clinic at Tawam hospital, United Arab Emirates, 2004-2005. Ann N Y Acad Sci; 2006 Nov;1084:319-24
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  • A retrospective audit of medical records of diabetic patients attending Tawam Hospital, a tertiary healthcare facility in the Al Ain region in the Emirate of Abu Dhabi, United Arab Emirates was performed.
  • An audit form was developed based on the priority aims and measures contained in the Institute for Clinical Systems Improvement (ICSI) Guidelines for the management of type 2 diabetes mellitus.

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  • (PMID = 17151311.001).
  • [ISSN] 0077-8923
  • [Journal-full-title] Annals of the New York Academy of Sciences
  • [ISO-abbreviation] Ann. N. Y. Acad. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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9. Herat A, Shirato K, Damian DL, Finlayson R, Whitfeld M: Invasive squamous cell carcinoma arising in refractory perianal Bowen's disease in a HIV-positive individual. Australas J Dermatol; 2006 May;47(2):120-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Invasive squamous cell carcinoma arising in refractory perianal Bowen's disease in a HIV-positive individual.
  • A 54-year-old HIV-positive homosexual man presented with erythematous and pigmented plaques on background erythema in the perianal region, histologically consistent with Bowen's disease.
  • Perianal Bowen's disease represents high-grade anal intraepithelial neoplasia, which is considered a precursor lesion of invasive anal squamous cell carcinoma.
  • This patient's anal intraepithelial neoplasia was unresponsive to multiple treatment modalities including cryotherapy, serial curettage and cautery, topical 5-fluorouracil and 5-aminolaevulinic acid photodynamic therapy.
  • He progressed to develop a poorly differentiated squamous cell carcinoma of the anus three and a half years after the Bowen's disease was diagnosed.
  • The squamous cell carcinoma was treated with combined chemoradiation.
  • A recurrence of high-grade anal intraepithelial neoplasia was noted 6 months after completion of chemoradiation.
  • [MeSH-major] Bowen's Disease / diagnosis. Carcinoma, Squamous Cell / diagnosis. HIV Infections. Neoplasm Recurrence, Local / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Anal Canal. Combined Modality Therapy. Diagnosis, Differential. Homosexuality, Male. Humans. Male. Middle Aged. Neoplasm Invasiveness


10. Whitsett T, Carpenter M, Lamartiniere CA: Resveratrol, but not EGCG, in the diet suppresses DMBA-induced mammary cancer in rats. J Carcinog; 2006 May 15;5:15
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  • Female Sprague-Dawley CD rats were exposed to either resveratrol (1 g/kg AIN-76A diet), EGCG (0.065% in the drinking water), or control diet (AIN-76A) for the entirety of their life starting at birth.
  • The epithelial cells of terminal end buds in the mammary glands of resveratrol-treated rats also showed an increase in apoptotic cells compared to the control or EGCG-treated rats as measured by a DNA fragmentation assay.

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  • (PMID = 16700914.001).
  • [ISSN] 1477-3163
  • [Journal-full-title] Journal of carcinogenesis
  • [ISO-abbreviation] J Carcinog
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P30 CA013148
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC1524738
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11. Craciunescu CN, Johnson AR, Zeisel SH: Dietary choline reverses some, but not all, effects of folate deficiency on neurogenesis and apoptosis in fetal mouse brain. J Nutr; 2010 Jun;140(6):1162-6
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  • Timed-pregnant mice were fed control (CT), folate-deficient (FD), or folate-deficient, choline-supplemented (FDCS) AIN-76 diets from d 11 to 17 (E11-17) of pregnancy, and on E17, fetal brains were collected for analysis.

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  • (PMID = 20392884.001).
  • [ISSN] 1541-6100
  • [Journal-full-title] The Journal of nutrition
  • [ISO-abbreviation] J. Nutr.
  • [Language] ENG
  • [Grant] United States / NIEHS NIH HHS / ES / P30 ES010126; United States / NIA NIH HHS / AG / AG09525; United States / NIDDK NIH HHS / DK / DK55865; United States / NIDDK NIH HHS / DK / DK56350
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] N91BDP6H0X / Choline
  • [Other-IDs] NLM/ PMC2869500
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12. Al-Daraji WI, Al-Mahmoud RM, Ilyas M: Gastric changes following colchicine therapy in patients with FMF. Dig Dis Sci; 2008 Aug;53(8):2079-82
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  • Colchicine is highly effective in the treatment of FMF and in preventing the development of recurrent attacks and amyloidosis, and it is essential to make the correct diagnosis and institute daily therapy with colchicine (0.5-0.6 mg bid).
  • METHODS: Biopsies were reviewed from 43 patients attending Ain Shams University Hospital (Egypt) who were diagnosed with FMF and treated with colchicine.
  • RESULTS: Three patients known to have FMF and on colchicine therapy showed typical histological features of colchicine (metaphase mitoses, epithelial pseudoproliferation, mucin depletion, and frequent apoptosis).

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  • [RetractionIn] Dig Dis Sci. 2009 Dec;54(12):2772 [19789978.001]
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  • (PMID = 18080195.001).
  • [ISSN] 0163-2116
  • [Journal-full-title] Digestive diseases and sciences
  • [ISO-abbreviation] Dig. Dis. Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Retracted Publication
  • [Publication-country] United States
  • [Chemical-registry-number] SML2Y3J35T / Colchicine
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13. Czoski-Murray C, Karnon J, Jones R, Smith K, Kinghorn G: Cost-effectiveness of screening high-risk HIV-positive men who have sex with men (MSM) and HIV-positive women for anal cancer. Health Technol Assess; 2010 Nov;14(53):iii-iv, ix-x, 1-101
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  • [Title] Cost-effectiveness of screening high-risk HIV-positive men who have sex with men (MSM) and HIV-positive women for anal cancer.
  • BACKGROUND: Anal cancer is uncommon and predominantly a disease of the elderly.
  • Individuals who are human immunodeficiency virus (HIV)-positive are particularly vulnerable to HPV infections, and increasing numbers from this population present with anal cancer.
  • OBJECTIVE: To estimate the cost-effectiveness of screening for anal cancer in the high-risk HIV-positive population [in particular, men who have sex with men (MSM), who have been identified as being at greater risk of the disease] by developing a model that incorporates the national screening guidelines criteria.
  • Papers that met the inclusion criteria contained the following: data on population incidence, effectiveness of screening, health outcomes or screening and/or treatment costs; defined suitable screening technologies; prospectively evaluated tests to detect anal cancer.
  • RESULTS: The reference case cost-effectiveness model for MSM found that screening for anal cancer is very unlikely to be cost-effective.
  • The negative aspects of screening included utility decrements associated with false-positive results and with treatment for high-grade anal intraepithelial neoplasia (HG-AIN).
  • However, combined with higher regression rates from low-grade anal intraepithelial neoplasia (LG-AIN), the lowest expected incremental cost-effectiveness ratio remained at over 44,000 pounds per quality-adjusted life-year (QALY) gained.
  • LIMITATIONS: Limited knowledge is available about the epidemiology and natural history of anal cancer, along with a paucity of good-quality evidence concerning the effectiveness of screening.
  • Further studies could assess whether the screening model has underestimated the impact of anal cancer, the results of which may justify an evaluative study of the effects of treatment for HG-AIN.
  • [MeSH-major] Anus Neoplasms / diagnosis. Anus Neoplasms / economics. HIV Infections / complications. Homosexuality, Male / statistics & numerical data. Mass Screening / economics


14. Hydration status and physiological workload of UAE construction workers: A prospective longitudinal observational study. J Occup Med Toxicol; 2008 Sep 18;3:21
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  • [Title] Hydration status and physiological workload of UAE construction workers: A prospective longitudinal observational study.
  • BACKGROUND: The objective of the study was to investigate the physiological responses of construction workers labouring in thermally stressful environments in the UAE using Thermal Work Limit (TWL) as a method of environmental risk assessment.
  • METHODS: The study was undertaken in May 2006.
  • Aural temperature, fluid intake, and urine specific gravity were recorded and continuous heart rate monitoring was used to assess fatigue.
  • Subjects were monitored over 3 consecutive shifts.
  • TWL and WBGT were used to assess the thermal stress.
  • RESULTS: Most subjects commenced work euhydrated and maintained this status over a 12-hour shift.
  • The average fluid intake was 5.44 L.
  • There were no changes in core temperature or average heart rate between day 1 and day 3, nor between shift start and finish, despite substantial changes in thermal stress.
  • The results obtained indicated that the workers were not physiologically challenged despite fluctuating harsh environmental conditions.
  • Core body temperatures were not elevated suggesting satisfactory thermoregulation.
  • CONCLUSION: The data demonstrate that people can work, without adverse physiological effects, in hot conditions if they are provided with the appropriate fluids and are allowed to self-pace.
  • The findings suggested that workers will self-pace according to the conditions.
  • The data also demonstrated that the use of WBGT (a widely used risk assessment tool) as a thermal index is inappropriate for use in Gulf conditions, however TWL was found to be a valuable tool in assessing thermal stress.

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  • (PMID = 18799015.001).
  • [ISSN] 1745-6673
  • [Journal-full-title] Journal of occupational medicine and toxicology (London, England)
  • [ISO-abbreviation] J Occup Med Toxicol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2561022
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15. Rady AE, Asal MK, Bassiony AA: The use of a constrained cementless acetabular component for instability in total hip replacement. Hip Int; 2010 Oct-Dec;20(4):434-9
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  • [Title] The use of a constrained cementless acetabular component for instability in total hip replacement.
  • Recurrent dislocation after total hip arthroplasty is a disabling complication that can be difficult to treat.
  • We evaluated the early clinical and radiographic outcome associated with the use of a constrained acetabular component for instability in total hip arthroplasty.
  • Fifteen patients underwent either primary or revision total hip arthroplasty with a cementless constrained acetabular component for different indications.
  • The mean patient age at surgery was 57.4 years and the mean clinical and radiological follow-up period was 26.4 months.
  • Clinical assessment was performed by the Harris hip score and at the latest follow up patients reported outcome using the Oxford hip score questionnaire.
  • All radiographs were evaluated for evidence of loosening.
  • Only one patient experienced redislocation with the constrained prosthesis.
  • The average Harris hip score increased from a preoperative mean of 22 (range, 16 - 36) to a postoperative mean of 85 (range, 66-94).
  • Preoperatively, the mean Oxford Hip Score was 48.6, which decreased to 20.5 at the final examination.
  • All but one of the 15 hips had a well-fixed, stable cup.
  •  Femoral component stability with bone ingrowth was achieved in 10 cases.
  • A constrained acetabular component is an effective option for the treatment of hip instability in primary and revision arthroplasty in those at high risk of dislocation.
  • The potential for aseptic loosening requires evaluation by long term studies.
  • [MeSH-major] Acetabulum / surgery. Arthroplasty, Replacement, Hip. Hip Joint / surgery. Hip Prosthesis. Joint Instability / surgery. Prosthesis Failure
  • [MeSH-minor] Activities of Daily Living. Aged. Cementation. Health Status Indicators. Hip Dislocation / etiology. Hip Dislocation / physiopathology. Hip Dislocation / surgery. Humans. Middle Aged. Prosthesis Design. Radiography. Range of Motion, Articular. Reoperation. Severity of Illness Index. Surveys and Questionnaires. Treatment Outcome

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  • (PMID = 21157746.001).
  • [ISSN] 1724-6067
  • [Journal-full-title] Hip international : the journal of clinical and experimental research on hip pathology and therapy
  • [ISO-abbreviation] Hip Int
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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16. Narchi H, Kochiyil J, Zayed R, Abdulrazzak W, Agarwal M: Maternal vitamin D status throughout and after pregnancy. J Obstet Gynaecol; 2010 Feb;30(2):137-42
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  • [Title] Maternal vitamin D status throughout and after pregnancy.
  • Prospective longitudinal study of vitamin D status and its risk factors in 75 pregnant women from early pregnancy until 6 months postpartum, by serial measurement of serum 25 (OH) vitamin D levels.
  • The serum levels at booking were not significantly different between nationalities (p = 0.06), parity (p = 0.2), education levels (p = 0.4), dress code (p > 0.5), consumption of vitamin D fortified milk (p = 0.2) or, fatty fish (p = 0.5), sun-exposed body surface area (p = 0.3), weekly time exposed to the sun (p = 0.08) or the sun exposure index (p = 0.2).
  • Vitamin D status progressively worsened as the proportion with adequate serum levels fell from 31% at the antenatal visit, to 23% after birth and 17%, 6 months later (p = 0.02).
  • While 80% of mothers who were exclusively breast-feeding had low vitamin D levels 6 months after delivery, this occurred in only 67% of those partially breast-feeding (p = 0.6).
  • [MeSH-major] Pregnancy Complications / ethnology. Vitamin D Deficiency / ethnology
  • [MeSH-minor] Adolescent. Adult. Female. Humans. Longitudinal Studies. Postpartum Period. Pregnancy. Prevalence. Prospective Studies. Risk Factors. United Arab Emirates / epidemiology. Young Adult

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  • (PMID = 20143971.001).
  • [ISSN] 1364-6893
  • [Journal-full-title] Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology
  • [ISO-abbreviation] J Obstet Gynaecol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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17. Bakir E: Photophysical properties of clozapine and determination of its concentration by using Eu(III)-dipicolinic acid complex as photo probe. Spectrochim Acta A Mol Biomol Spectrosc; 2010 Jan;75(1):490-2
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  • [Title] Photophysical properties of clozapine and determination of its concentration by using Eu(III)-dipicolinic acid complex as photo probe.
  • Clozapine drug is photo-stable under irradiation of light for a long time, so we can store it in difficult and hot conditions.
  • In addition the activity of clozapine is inhibited of the absorption spectra in the presence of glucose and enhanced in the presence of iron(III).
  • We succeeded in detecting the concentration of clozapine in the range 1-60x10(-9)M using Eu(III)-dipicolinic acid complex as photo probe type and using Stern-Völmer equation to determine the Stern-Völmer constant, critical radius and the mechanism of quenching of luminescence of Eu(III)-dipicolinic acid complex is found to be of dipolar-dipolar interaction.
  • [MeSH-major] Antipsychotic Agents / chemistry. Chelating Agents / chemistry. Clozapine / chemistry. Europium / chemistry. Photochemistry / methods. Picolinic Acids / chemistry
  • [MeSH-minor] Molecular Structure

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  • [Copyright] Copyright 2009 Elsevier B.V. All rights reserved.
  • (PMID = 19948424.001).
  • [ISSN] 1873-3557
  • [Journal-full-title] Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
  • [ISO-abbreviation] Spectrochim Acta A Mol Biomol Spectrosc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antipsychotic Agents; 0 / Chelating Agents; 0 / Picolinic Acids; 444W947O8O / Europium; J60AR2IKIC / Clozapine; UE81S5CQ0G / dipicolinic acid
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18. Abouzid K, Frohberg P, Lehmann J, Decker M: 6-aryl-4-oxohexanoic acids: synthesis, effects on eicosanoid biosynthesis, and anti-inflammatory in vivo-activities. Med Chem; 2007 Sep;3(5):433-8
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  • [Title] 6-aryl-4-oxohexanoic acids: synthesis, effects on eicosanoid biosynthesis, and anti-inflammatory in vivo-activities.
  • The synthesis of a series of 6-aryl-4-oxohexanoic acids is described: This involves condensation of an appropriate aldehyde (Ia-f) and levulenic acid using catalytic amounts of piperidine and acetic acid in toluene to afford the 6-aryl-4-oxohex-5-enoic acids (IIa-f).
  • The arylidene derivatives (IIa-d) were reduced by hydrogen at room temperature using palladium (10 %/carbon) as catalyst to produce 6-aryl-4-oxohexanoic acids (IIIa-d) as target compounds.
  • In certain instances, the lactone derivative (IVd) was obtained as a low-melting by-product.
  • These compounds were tested in two models used for evaluating the activity of non-steroidal anti-inflammatory drugs (NSAIDs).
  • The first test is the effect of the synthesized compounds on arachidonic acid metabolism in vitro using human whole blood assay.
  • The second is the in vivo carrageenan induced rat paw edema test.
  • Compound IIe showed higher in vivo-activity compared to fenbufen at the same dose level (50mg/kg).
  • [MeSH-major] Anti-Inflammatory Agents, Non-Steroidal / chemical synthesis. Anti-Inflammatory Agents, Non-Steroidal / pharmacology. Caproates / chemical synthesis. Caproates / pharmacology. Eicosanoids / biosynthesis
  • [MeSH-minor] Animals. Cyclooxygenase Inhibitors / chemical synthesis. Cyclooxygenase Inhibitors / pharmacology. Lipoxygenase Inhibitors / chemical synthesis. Lipoxygenase Inhibitors / pharmacology. Magnetic Resonance Spectroscopy. Rats. Spectrometry, Mass, Electrospray Ionization. Spectrophotometry, Infrared

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  • (PMID = 17897067.001).
  • [ISSN] 1573-4064
  • [Journal-full-title] Medicinal chemistry (Shāriqah (United Arab Emirates))
  • [ISO-abbreviation] Med Chem
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; 0 / Caproates; 0 / Cyclooxygenase Inhibitors; 0 / Eicosanoids; 0 / Lipoxygenase Inhibitors
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19. Adeghate E, Christopher Howarth F, Rashed H, Saeed T, Gbewonyo A: The effect of a fat-enriched diet on the pattern of distribution of pancreatic islet cells in the C57BL/6J mice. Ann N Y Acad Sci; 2006 Nov;1084:361-70
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  • [Title] The effect of a fat-enriched diet on the pattern of distribution of pancreatic islet cells in the C57BL/6J mice.
  • The C57BL/6J mice are inbred strains and develop the metabolic syndrome of obesity, hyperinsulinemia, hyperglycemia, and hypertension, when fed a high-fat diet.
  • These features are similar to those observed in the human metabolic syndrome.
  • This article examined the effect of fat-enriched (FE) diet on the pattern of distribution of insulin-, glucagon-, somatostatin-, and pancreatic polypeptide (PP)-positive cells in the pancreatic islets of C57BL/6J mice using immunohistochemical methods.
  • Insulin-immunoreactive cells were observed in both the peripheral and central regions of the islets of Langerhans in both FE- and control diet-fed mice.
  • The percentage distribution of insulin-positive cells was similar in FE (83.5 +/- 6.4) compared to control diet-fed C57BL/6J mice (83.8 +/- 6.5).
  • Glucagon-containing cells were discerned in the periphery of pancreatic islets in both FE- and control diet-fed mice.
  • The percentage distribution of glucagon was not statistically different in mice fed with FE (9.9 +/- 2.7) compared to control diet (11.3 +/- 4.9).
  • Somatostatin-positive cells were seen in the outer part of the islet of Langerhans and constitute 12.1% (+/-6.3) and 10% (+/-5.5) of pancreatic islet cells in FE- and control diet-fed mice, respectively.
  • PP-immunoreactive cells were observed in the peripheral region of the pancreatic islets of both FE- and control diet-fed mice.
  • The percentage distribution of PP-positive cells was significantly (2.0 +/- 1.2) lower compared to control (5.1 +/- 2.4).
  • In conclusion, the number of PP is significantly reduced in FE diet-fed mice and may play a role in the pathogenesis of diet-induced metabolic syndrome in C57BL/6J mice.
  • [MeSH-major] Dietary Fats / pharmacology. Islets of Langerhans / cytology. Islets of Langerhans / physiology
  • [MeSH-minor] Animals. Immunohistochemistry. Lymphoid Tissue / cytology. Lymphoid Tissue / physiology. Male. Mice. Mice, Inbred C57BL

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  • (PMID = 17151315.001).
  • [ISSN] 0077-8923
  • [Journal-full-title] Annals of the New York Academy of Sciences
  • [ISO-abbreviation] Ann. N. Y. Acad. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Dietary Fats
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20. Cascio BM, Wilckens JH, Ain MC, Toulson C, Frassica FJ: Documentation of acute compartment syndrome at an academic health-care center. J Bone Joint Surg Am; 2005 Feb;87(2):346-50
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  • [MeSH-major] Compartment Syndromes / diagnosis. Compartment Syndromes / surgery. Documentation. Fascia / surgery. Medical Records

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  • (PMID = 15687158.001).
  • [ISSN] 0021-9355
  • [Journal-full-title] The Journal of bone and joint surgery. American volume
  • [ISO-abbreviation] J Bone Joint Surg Am
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
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21. Eid HO, Barss P, Adam SH, Torab FC, Lunsjo K, Grivna M, Abu-Zidan FM: Factors affecting anatomical region of injury, severity, and mortality for road trauma in a high-income developing country: lessons for prevention. Injury; 2009 Jul;40(7):703-7
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  • METHODS: Data of the Trauma Registry of Al Ain city were collected prospectively over 3 years (2003-2006) at the main trauma hospital.

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  • [CommentIn] Injury. 2011 Sep;42(9):967 [21497810.001]
  • (PMID = 19117565.001).
  • [ISSN] 1879-0267
  • [Journal-full-title] Injury
  • [ISO-abbreviation] Injury
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
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22. Hirao A, Tahara Y, Kimura I, Shibata S: A balanced diet is necessary for proper entrainment signals of the mouse liver clock. PLoS One; 2009;4(9):e6909
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  • AIN-93M formula [0.6-0.85 g/10 g mouse BW] (composition: 14% casein, 47% cornstarch, 15% gelatinized cornstarch, 10% sugar, 4% soybean oil, and 10% other [fiber, vitamins, minerals, etc.
  • When cornstarch in AIN-93M was substituted with glucose, sucrose, fructose, polydextrose, high-amylose cornstarch, or gelatinized cornstarch, the amplitude of phase advance paralleled the increase in blood glucose concentration.

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  • (PMID = 19738906.001).
  • [ISSN] 1932-6203
  • [Journal-full-title] PloS one
  • [ISO-abbreviation] PLoS ONE
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Blood Glucose; 0 / Caseins; 0 / Per2 protein, mouse; 0 / Period Circadian Proteins; 0 / Vitamins; IY9XDZ35W2 / Glucose
  • [Other-IDs] NLM/ PMC2734168
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23. Saleh NK, Saleh HA: Olive oil improved the impairment of in vitro insulin-stimulated glucose uptake by diaphragm in ovariectomized female Wistar rats. Exp Gerontol; 2010 Dec;45(12):964-9
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  • [Title] Olive oil improved the impairment of in vitro insulin-stimulated glucose uptake by diaphragm in ovariectomized female Wistar rats.
  • This work was carried out to examine the impact of ovariectomy in female Wistar rats on in vitro basal and insulin-stimulated glucose uptake by diaphragm, and the possible beneficial effects of olive oil supplementation in these rats.
  • METHODS: we studied 21 female Wistar rats aged 12-14 months, divided into three groups: sham-operated control (SHAM), ovariectomized (OVX), and ovariectomized rats supplemented with extra-virgin olive oil (Olive-OVX) orally for 12 weeks; 4 weeks before ovariectomy and 8 weeks after.
  • At the end of the experiment, blood samples were collected for lipid profile assays.
  • Malondialdehyde (MDA) in soleus muscles was assayed.
  • The diaphragms were collected for determination of glucose uptake by the muscles.
  • Soleus muscles and pancreas were processed for histological examination.
  • RESULTS: ovariectomy impaired insulin-stimulated glucose uptake by diaphragm of female rats, induced abnormalities of lipid metabolism, and increased the oxidative stress marker, MDA level in soleus muscles.
  • Olive oil supplementation to ovariectomized rats resulted in an enhancement of insulin-stimulated glucose uptake by diaphragm and a better lipid profile, as well as a decrease in the MDA level in soleus muscles.
  • Histological study in OVX rats revealed a decrease in the size and number of islets of Langerhans in the pancreatic tissue, and decreases in both glycogen content, and in mitochondrial density in the soleus muscles.
  • In Olive-OVX rats the size of islets of Langerhans was normal, and muscle glycogen, and muscle mitochondrial density were increased as compared to OVX rats.
  • CONCLUSION: ovariectomy impaired in vitro insulin-stimulated glucose uptake by diaphragm.
  • The improvement of this impairment by olive oil supplementation could be attributed to its antioxidant properties, its high content of monounsaturated fatty acids, as well as, its enhancement effect on mitochondrial density in skeletal muscles.
  • [MeSH-major] Diaphragm / drug effects. Diaphragm / metabolism. Glucose / metabolism. Insulin / pharmacology. Ovariectomy. Plant Oils / pharmacology
  • [MeSH-minor] Animals. Body Mass Index. Female. Lipids / blood. Malondialdehyde / metabolism. Mitochondria, Muscle / drug effects. Models, Animal. Muscle, Skeletal / drug effects. Muscle, Skeletal / metabolism. Muscle, Skeletal / pathology. Olive Oil. Oxidative Stress / drug effects. Pancreas / drug effects. Rats. Rats, Wistar

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  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20817087.001).
  • [ISSN] 1873-6815
  • [Journal-full-title] Experimental gerontology
  • [ISO-abbreviation] Exp. Gerontol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Insulin; 0 / Lipids; 0 / Olive Oil; 0 / Plant Oils; 4Y8F71G49Q / Malondialdehyde; IY9XDZ35W2 / Glucose
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24. Atwa K, Abuhasna S, Shihab Z, Hashaykeh N, Hasan R: Acute pulmonary toxicity following intralesional administration of bleomycin for a lymphovenous malformation. Pediatr Pulmonol; 2010 Feb;45(2):192-6
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  • [Title] Acute pulmonary toxicity following intralesional administration of bleomycin for a lymphovenous malformation.
  • OBJECTIVE: To describe the clinical course and treatment of an infant with acute pulmonary toxicity following intralesional administration of bleomycin for a lymphovenous malformation.
  • DESIGN: Case report.
  • SETTING: A tertiary care University-affiliated hospital.
  • PATIENT, INTERVENTION, AND RESULTS: An 8-month-old girl developed acute respiratory distress with profound hypoxemia complicated by pneumothorax and pneumomediastinum 1 day following intralesional administration of bleomycin.
  • She was treated with bilateral chest tube insertion, systemic corticosteroids, pentoxifylline, and supportive care.
  • At the most recent follow-up 5 months after the onset of the respiratory event, the patient is active, walks, and talks without any evidence of pulmonary diseases clinically.
  • This is the youngest infant reported, to date, with acute bleomycin pulmonary toxicity following intralesional administration of bleomycin resulting in acute respiratory insufficiency followed by complete recovery.
  • CONCLUSIONS: This case illustrates the importance of early recognition and aggressive treatment of acute bleomycin toxicity resulting from intralesional administration of this medication for lymphovenous malformations.
  • [MeSH-major] Airway Obstruction / drug therapy. Antibiotics, Antineoplastic / adverse effects. Bleomycin / adverse effects. Lymphatic Abnormalities / drug therapy
  • [MeSH-minor] Adrenal Cortex Hormones / therapeutic use. Female. Humans. Infant. Injections, Intralesional. Pentoxifylline / therapeutic use. Treatment Outcome

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  • [Copyright] (c) 2009 Wiley-Liss, Inc.
  • (PMID = 19953580.001).
  • [ISSN] 1099-0496
  • [Journal-full-title] Pediatric pulmonology
  • [ISO-abbreviation] Pediatr. Pulmonol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Adrenal Cortex Hormones; 0 / Antibiotics, Antineoplastic; 11056-06-7 / Bleomycin; SD6QCT3TSU / Pentoxifylline
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25. Agha SH, Pilla F, Galal S, Shaat I, D'Andrea M, Reale S, Abdelsalam AZ, Li MH: Genetic diversity in Egyptian and Italian goat breeds measured with microsatellite polymorphism. J Anim Breed Genet; 2008 Jun;125(3):194-200
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  • [Title] Genetic diversity in Egyptian and Italian goat breeds measured with microsatellite polymorphism.
  • Seven microsatellite markers were used to study genetic diversity of three Egyptian (Egyptian Baladi, Barki and Zaraibi) and two Italian (Maltese and Montefalcone) goat breeds.
  • The microsatellites showed a high polymorphic information content (PIC) of more than 0.5 in most of the locus-breed combinations and indicated that the loci were useful in assessing within- and between-breed variability of domestic goat (Capra hircus).
  • The expected heterozygosity of the breeds varied from 0.670 to 0.792.
  • In the geographically wider distributed Egyptian Baladi breed there were indications for deviations from random breeding.
  • Analysis of genetic distances and population structure grouped the three Egyptian goat breeds together, and separated them from the two Italian breeds.
  • The studied Mediterranean breeds sampled from African and European populations seem to have differentiated from each other with only little genetic exchange between the geographically isolated populations.
  • [MeSH-major] Goats / genetics
  • [MeSH-minor] Animals. Breeding. Egypt. Female. Genetic Variation. Heterozygote. Italy. Male. Microsatellite Repeats. Polymorphism, Genetic. Species Specificity

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  • (PMID = 18479270.001).
  • [ISSN] 0931-2668
  • [Journal-full-title] Journal of animal breeding and genetics = Zeitschrift für Tierzüchtung und Züchtungsbiologie
  • [ISO-abbreviation] J. Anim. Breed. Genet.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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26. Ramzy RM, Goldman AS, Kamal HA: Defining the cost of the Egyptian lymphatic filariasis elimination programme. Filaria J; 2005 Aug 2;4:7
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  • [Title] Defining the cost of the Egyptian lymphatic filariasis elimination programme.
  • BACKGROUND: Lymphatic filariasis (LF) is targeted for global elimination.
  • LF elimination programmes in different countries, including Egypt, are supported financially by national and international agencies.
  • The national programme in Egypt is based on mass drug administration (MDA) of an annual dose of a combination of 2 drugs (DEC and albendazole) to all endemic villages.
  • This study aimed primarily to estimate the Total and Government costs of two rounds of MDA conducted in Egypt in 2000 and 2001, the average cost per person treated, and the cost share of the different programme partners.
  • METHODS: The Total costs reflect the overall annual costs of the MDA programme, and we defined Government costs as those expenditures made by the Egyptian government to develop, implement and sustain the MDA programmes.
  • We used a generic protocol developed in coordination with the Emory Lymphatic Filariasis Support Center.
  • Our study was concerned with all costs to the government, donors and other implementing parties.
  • Cost data were retrospectively gathered from local, regional and national Ministry of Health and Population records.
  • The total estimates for each governorate were based on data from a representative district for the governorate; these were combined with national programme data for a national estimate.
  • RESULTS: The overall Total and Government costs for treating approximately 1,795,553 individuals living in all endemic villages in the year 2000 were USD 3,181,000 and USD 2,412,000, respectively.
  • In 2001, the number of persons treated increased (29%) and the Total costs were USD 3,109,000 while Government costs were USD 2,331,000.
  • In 2000, the average Total and Government costs per treated subject were USD 1.77 and USD 1.34, respectively, however, these costs decreased to USD 1.34 and USD 1.00, respectively in 2001.
  • The coverage rate was 86.0% in 2000 and it increased to 88.0% in 2001.
  • CONCLUSION: The Egyptian government provided 75.8% of all resources, as reflected in the Total cost estimates, and international agencies contributed the rest.
  • Such data highlight both the commitment of the Egyptian government and the significance of the contributions of international bodies toward the LF elimination programme.

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  • (PMID = 16076397.001).
  • [ISSN] 1475-2883
  • [Journal-full-title] Filaria journal
  • [ISO-abbreviation] Filaria J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1187908
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27. El Guindy AA, Nabhan AF: A randomized trial of tight vs. less tight control of mild essential and gestational hypertension in pregnancy. J Perinat Med; 2008;36(5):413-8
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  • METHODS: A randomized trial was conducted in 2006-2007 in the University of Ain Shams, Egypt.


28. Ismail NA, Ahmed HA: Knowledge, Attitudes and Practices Related to Avian Influenza among a Rural Community in Egypt. J Egypt Public Health Assoc; 2010;85(1-2):73-96
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  • [Title] Knowledge, Attitudes and Practices Related to Avian Influenza among a Rural Community in Egypt.
  • BACKGROUND: Avian influenza (AI) is currently a threat to global health.
  • Prevention and control largely depend on population awareness and behavior.
  • AIM OF STUDY: Is to assess the rural community knowledge, attitudes, and practice (KAP) related to AI prevention and control.
  • MATERIAL AND METHODS: A household survey, using an interviewing questionnaire and observational checklist, was conducted in Bahetim district, Qalubeya Governorate.
  • RESULTS: Of the total 399, 41.1% were dealing with poultry, of them 26% were raising poultry at their home.
  • Vaccination of birds were reported by 66.6% of the respondents, hand washing regularly with water and soap by 54.6%, and by going far away from infected birds by 51.3%.
  • Nearly 50% mentioned that AI disease cannot be transmitted from person to person and that AI is transmitted to human through contact with sick birds.
  • Regarding their score level, 75.7% of the respondents had fair knowledge level, 87.5% had positive attitude towards prevention and control of AI and 58.1% had fair practice level.
  • Younger persons, those who had completed secondary or higher level of education, those living in nuclear family had better knowledge and positive attitudes towards AI prevention and control (p < 0.05), while age, sex, and education level did not affect their healthy behavior and sanitary practices.
  • CONCLUSIONS AND RECOMMENDATIONS: The level of community knowledge and practices about AI disease was moderate, but their attitudes were positive.
  • Therefore, designing and implementing health educational programs about AI to improve the community practices should have the priority to encourage people to take a more active role.
  • [MeSH-major] Health Knowledge, Attitudes, Practice. Influenza in Birds. Influenza, Human. Rural Population / statistics & numerical data
  • [MeSH-minor] Adolescent. Adult. Animal Husbandry. Animals. Cross-Sectional Studies. Egypt. Female. Humans. Male. Middle Aged. Poultry. Surveys and Questionnaires. Young Adult

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  • (PMID = 21073849.001).
  • [ISSN] 0013-2446
  • [Journal-full-title] The Journal of the Egyptian Public Health Association
  • [ISO-abbreviation] J Egypt Public Health Assoc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
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29. Conlon JM, Leprince J: Identification and analysis of bioactive peptides in amphibian skin secretions. Methods Mol Biol; 2010;615:145-57
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  • [Title] Identification and analysis of bioactive peptides in amphibian skin secretions.
  • Skin secretions from anurans (frogs and toads), particularly those species belonging to the Hylidae and Ranidae families, are a rich source of biologically active peptides.
  • Cytolytic peptides with broad-spectrum antimicrobial activities and highly variable amino acid sequences are often released into these secretions in high concentrations.
  • Identification and characterization of these components can prove to be valuable in species identification, elucidation of evolutionary histories and phylogenetic relationships between species, and may lead to development of agents with potential for therapeutic application.
  • This chapter describes the use of norepinephrine (injection or immersion) to stimulate peptide release in a procedure that does not appear to cause distress to the animals.
  • The peptide components in the secretions are separated by reversed-phase HPLC on octadecylsilyl silica (C(18)) columns under standard conditions after partial purification on Sep-Pak cartridges.
  • Individual peptides are identified by determination of their molecular masses by MALDI-TOF mass spectrometry and from their retention times.
  • The use of mixtures of synthetic peptides of appropriate molecular mass as calibration standards enables mass determination to a high degree of precision.
  • [MeSH-major] Anura / metabolism. Bodily Secretions / chemistry. Peptides / analysis. Skin / chemistry
  • [MeSH-minor] Animals. Chromatography, High Pressure Liquid / instrumentation. Chromatography, High Pressure Liquid / methods. Molecular Weight. Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods

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  • (PMID = 20013207.001).
  • [ISSN] 1940-6029
  • [Journal-full-title] Methods in molecular biology (Clifton, N.J.)
  • [ISO-abbreviation] Methods Mol. Biol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Peptides
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30. el-Khateeb EA: Bullous congenital ichthyosiform erythroderma associated with hypocalcemic vitamin D-resistant rickets. Pediatr Dermatol; 2008 Mar-Apr;25(2):279-82
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  • [Title] Bullous congenital ichthyosiform erythroderma associated with hypocalcemic vitamin D-resistant rickets.
  • There are several reports of an association between ichthyosis and rickets based mainly on a causative relationship through the impaired ability of ichthyotic skin to synthesize vitamin D.
  • Hypocalcemic vitamin D-resistant rickets represents a specific type of rickets that is attributed to vitamin D receptor defect rather than to vitamin D deficiency.
  • Nevertheless, an extremely rare association between bullous congenital ichthyosiform erythroderma and hypocalcemic vitamin D-resistant rickets is presented.
  • [MeSH-major] Familial Hypophosphatemic Rickets / complications. Hyperkeratosis, Epidermolytic / complications
  • [MeSH-minor] Child. Humans. Hypocalcemia / complications. Male. Skin / pathology


31. Montasser AA: Gram-negative bacteria from the camel tick Hyalomma dromedarii (Ixodidae) and the chicken tick Argas persicus (Argasidae) and their antibiotic sensitivities. J Egypt Soc Parasitol; 2005 Apr;35(1):95-106
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  • [Title] Gram-negative bacteria from the camel tick Hyalomma dromedarii (Ixodidae) and the chicken tick Argas persicus (Argasidae) and their antibiotic sensitivities.
  • A total of nine species of gram-negative bacteria were isolated from organs and haemolymph of the hard tick Hyalomma (Hyalomma) dromedarii and the soft tick Argas (Persicargas) persicus.
  • Four species namely Serratia liquefaciens, Stenotrophomonas maltophilia, Klebsiella ornithinolytica and Aeromonas hydrophila were isolated from H. dromedarii and five species namely Rahnella aquatilis, Pseudomonas fluorescens, Enterobacter cloacae, Chryseomonas luteola and Chryseobacterium meningosepticum were isolated from A. persicus.
  • Isolated bacteria were identified using the analytical profile index 20E.
  • Disk diffusion test was carried out on all isolated bacteria to determine antibiotic sensitivity of chloramphenicol, amoxillin/clavulanic acid, neomycin, streptomycin, triplesulphur tetracycline and nitrofurantion.
  • The results were discussed.
  • [MeSH-major] Anti-Bacterial Agents / pharmacology. Argasidae / microbiology. Gram-Negative Bacteria / drug effects. Gram-Negative Bacteria / isolation & purification. Ixodidae / microbiology
  • [MeSH-minor] Animals. Camels / parasitology. Chickens / parasitology. Drug Resistance, Bacterial. Microbial Sensitivity Tests. Poultry Diseases / parasitology. Species Specificity. Tick Infestations / parasitology. Tick Infestations / veterinary

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  • (PMID = 15880998.001).
  • [ISSN] 1110-0583
  • [Journal-full-title] Journal of the Egyptian Society of Parasitology
  • [ISO-abbreviation] J Egypt Soc Parasitol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents
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32. El-Demerdash E, Awad AS, Taha RM, El-Hady AM, Sayed-Ahmed MM: Probucol attenuates oxidative stress and energy decline in isoproterenol-induced heart failure in rat. Pharmacol Res; 2005 Apr;51(4):311-8
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  • [Title] Probucol attenuates oxidative stress and energy decline in isoproterenol-induced heart failure in rat.
  • In the present study, we examined whether the powerful antioxidant probucol (a clinically used lipid-lowering drug) would attenuate the oxidative stress and energy starvation in experimental model of heart failure (HF) using isoproterenol.
  • Rats were injected subcutaneously with isoproterenol (2.4 mgkg-1) daily for 1 week, and then treated with probucol (61 mg/kg) daily for 2 weeks.
  • Oxidative stress was assessed by measuring myocardial lipid peroxides level and antioxidant enzymes activities, glutathione peroxidase (GPx) and superoxide dismutase.
  • In addition, cardiac metabolic damage was estimated by measuring myocardial ATP, ADP and AMP levels as well as ATP/ADP ratio.
  • It was found that isoproterenol induced a significant increase in heart rate by approximately 30% as compared with the pre-value.
  • These changes were significantly attenuated by post-treatment of rats with probucol.
  • Also, isoproterenol induced several pathological changes including lymphocyte infiltration, myofibrillar hemorrhage and degeneration, and these changes were attenuated by probucol.
  • In addition, animals treated with isoproterenol showed a significant increase in myocardial lipid peroxides level up to 163% and a significant decrease in myocardial GPx activity by 35% as compared with the control group.
  • Probucol not only counteracted significantly the pronounced oxidative stress effect of isoproterenol but also it induced a significant increase in myocardial GPx as compared with the control group.
  • The major new finding of the present study is that treatment with probucol induced a significant increase in myocardial ATP level (the source of energy) and ATP/ADP ratio.
  • Moreover, there is a significant correlation between ATP/ADP ratio and myocardial probucol level.
  • In conclusion, the cardioprotective effect of probucol in treatment of HF is a result of not only its antioxidant properties and an enhancement of endogenous antioxidant reserve (mainly GPx) but also an enhancement of myocardial energy state.
  • [MeSH-major] Energy Metabolism / drug effects. Heart Failure / chemically induced. Heart Failure / drug therapy. Isoproterenol / toxicity. Oxidative Stress / drug effects. Probucol / therapeutic use
  • [MeSH-minor] Animals. Heart Rate / drug effects. Heart Rate / physiology. Male. Myocardium / metabolism. Rats

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  • (PMID = 15683744.001).
  • [ISSN] 1043-6618
  • [Journal-full-title] Pharmacological research
  • [ISO-abbreviation] Pharmacol. Res.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] L628TT009W / Isoproterenol; P3CTH044XJ / Probucol
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33. Dash N, Ameen AS, Sheek-Hussein MM, Smego RA Jr: Epidemiology of meningitis in Al-Ain, United Arab Emirates, 2000-2005. Int J Infect Dis; 2007 Jul;11(4):309-12
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  • [Title] Epidemiology of meningitis in Al-Ain, United Arab Emirates, 2000-2005.
  • OBJECTIVE: To describe the epidemiologic features of meningitis in Al-Ain Medical District, United Arab Emirates from January 2000 through June 2005.
  • METHODS: A retrospective review of clinical records and notification forms for cases of meningitis reported to the Department of Preventive Medicine, Al-Ain.
  • The incidence rate of meningitis in Al-Ain ranged between 2.2/100,000 population in 2000 and 1/100,000 in 2005, with an overall downward trend by year.

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  • (PMID = 16950640.001).
  • [ISSN] 1201-9712
  • [Journal-full-title] International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
  • [ISO-abbreviation] Int. J. Infect. Dis.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
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34. Ain R, Canham LN, Soares MJ: Dexamethasone-induced intrauterine growth restriction impacts the placental prolactin family, insulin-like growth factor-II and the Akt signaling pathway. J Endocrinol; 2005 May;185(2):253-63
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  • [Title] Dexamethasone-induced intrauterine growth restriction impacts the placental prolactin family, insulin-like growth factor-II and the Akt signaling pathway.
  • Intrauterine growth restriction (IUGR) is a major cause of perinatal death and neonatal morbidity and mortality.
  • There are numerous causes of IUGR.
  • Glucocorticoid-induced IUGR is highly relevant because administration of synthetic glucocorticoids, principally dexamethasone, to women threatened by premature labor is widely used in clinical practice.
  • Fetal growth is directly related to placental growth and development.
  • In this report, we analyzed the effect of dexamethasone on placental development in the rat.
  • Dexamethasone administered between days 13 and 20 of pregnancy not only induced IUGR but also decreased placental mass by approximately 50%.
  • Impaired placental development was associated with dysregulated placental prolactin (PRL) family and insulin-like growth factor-II (IGF-II) gene expression.
  • Furthermore, there was a significant decrease in the activation of Akt/protein kinase B in the junctional zone of the placenta, as assessed by the phosphorylation status of Akt and the pro-apoptotic protein BAD, a downstream target of the Akt signaling pathway.
  • Such changes are consistent with increases in indices of apoptosis, including increased cleavage of poly(ADP-ribose) polymerase (PARP) in the junctional zone of the placenta of dexamethasone-treated rats.
  • In summary, dexamethasone-induced IUGR is associated with placental insufficiency, including dysregulated placental hormone/cytokine gene expression and down-regulation of the IGF-II/Akt signaling pathway resulting in increases in indices of placental apoptosis.
  • [MeSH-major] Dexamethasone / adverse effects. Fetal Growth Retardation / metabolism. Glucocorticoids / adverse effects. Placental Insufficiency / metabolism. Prolactin / metabolism. Signal Transduction / drug effects
  • [MeSH-minor] Animals. Apoptosis. Blotting, Northern / methods. Blotting, Western / methods. Carrier Proteins / metabolism. Female. Gene Expression / drug effects. In Situ Hybridization / methods. Insulin-Like Growth Factor II / analysis. Insulin-Like Growth Factor II / metabolism. Oligonucleotide Array Sequence Analysis. Placenta / drug effects. Placenta / metabolism. Pregnancy. Protein-Serine-Threonine Kinases / analysis. Protein-Serine-Threonine Kinases / metabolism. Proto-Oncogene Proteins / analysis. Proto-Oncogene Proteins / metabolism. Proto-Oncogene Proteins c-akt. Rats. Rats, Sprague-Dawley. bcl-Associated Death Protein

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  • (PMID = 15845918.001).
  • [ISSN] 0022-0795
  • [Journal-full-title] The Journal of endocrinology
  • [ISO-abbreviation] J. Endocrinol.
  • [Language] eng
  • [Grant] United States / NICHD NIH HHS / HD / HD20676; United States / NICHD NIH HHS / HD / HD39878
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Bad protein, rat; 0 / Carrier Proteins; 0 / Glucocorticoids; 0 / Proto-Oncogene Proteins; 0 / bcl-Associated Death Protein; 67763-97-7 / Insulin-Like Growth Factor II; 7S5I7G3JQL / Dexamethasone; 9002-62-4 / Prolactin; EC 2.7.11.1 / Akt1 protein, rat; EC 2.7.11.1 / Protein-Serine-Threonine Kinases; EC 2.7.11.1 / Proto-Oncogene Proteins c-akt
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35. Li Y, Yang Z, Chen Z, Zhou Z: Computational investigation on structural and physical properties of AIN nanosheets and nanoribbons. J Nanosci Nanotechnol; 2010 Nov;10(11):7200-3
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  • [Title] Computational investigation on structural and physical properties of AIN nanosheets and nanoribbons.
  • Through first-principles computations, we investigated the structural, electronic and magnetic properties of two-dimensional AIN single layer and one-dimensional AIN nanoribbons.
  • AIN single layer and nanoribbons quit the Wurtzite configuration and adopt a graphitic-like structure after geometry optimization.
  • Both hydrogen-terminated zigzag and armchair AIN nanoribbons have a direct band gap, which increases monotonically with increasing ribbon width.
  • Bare zigzag AIN nanoribbons have a spin-polarized ground state and are magnetic semiconductors.
  • The results may promote the experimental preparation of AIN nanosheets and nanoribbons and their applications to nanotechnology.

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  • (PMID = 21137897.001).
  • [ISSN] 1533-4880
  • [Journal-full-title] Journal of nanoscience and nanotechnology
  • [ISO-abbreviation] J Nanosci Nanotechnol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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36. Saeed SA, Elsharkawy M, Elsaeed K, Fooda O: Paraoxonase-1 (PON1) activity as a risk factor for atherosclerosis in chronic renal failure patients. Hemodial Int; 2008 Oct;12(4):471-9
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  • [Title] Paraoxonase-1 (PON1) activity as a risk factor for atherosclerosis in chronic renal failure patients.
  • Paraoxonase is a high-density lipoprotein-associated enzyme and has been shown to reduce the susceptibility to low-density lipoprotein peroxidation.
  • This study aimed to investigate the activity of serum paraoxonase in uremic patients on hemodialysis (HD) and in the predialysis period, and to evaluate the correlations of vascular disease with paraoxonase activity.
  • Thirty patients with chronic renal failure (CRF) undergoing HD (group 1), 30 patients with CRF under conservative treatment (group 2), and 30 healthy controls (group 3) were included.
  • Basal, salt-stimulated, and arylesterase activity were tested by UV spectrophotometry.
  • Serum lipid parameters were determined.
  • B-Mode Doppler ultrasound was used to assess common carotid intima-media thickness (IMT).
  • Basal paraoxonase, salt-stimulated, and arylesterase activity showed no significant difference between group 1 and group 2.
  • However, it was significantly lower in group 1 and in group 2 than controls.
  • Carotid IMT was significantly higher in group 1 than group 2 and both were significantly higher than controls.
  • Basal paraoxonase-1 (PON1), salt-stimulated PON1, and arylesterase activity correlate with BUN, but only basal PON1 and salt-stimulated PON1 correlate with serum albumin.
  • Linear regression showed that the most significant determinant of carotid IMT was PON1 arylesterase activity in group 1 and arylesterase activity and basal PON1 activity in group 2.
  • Patients with CRF, whether under HD or conservative treatment, have reduced basal and stimulated paraoxonase activities, and this could be an important factor causing increased vascular disease in those patients.
  • Modifying this factor can be of great value to protect against this common complication.
  • [MeSH-major] Aryldialkylphosphatase / blood. Carotid Artery Diseases / epidemiology. Carotid Artery Diseases / metabolism. Kidney Failure, Chronic / epidemiology. Kidney Failure, Chronic / metabolism. Renal Dialysis / statistics & numerical data
  • [MeSH-minor] Adult. Blood Urea Nitrogen. C-Reactive Protein / metabolism. Carboxylic Ester Hydrolases / blood. Enzyme Activation. Female. Humans. Linear Models. Logistic Models. Male. Middle Aged. Risk Factors. Tunica Intima / ultrasonography. Tunica Media / ultrasonography. Uremia / epidemiology. Uremia / metabolism. Uremia / therapy. Young Adult

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  • (PMID = 19090870.001).
  • [ISSN] 1492-7535
  • [Journal-full-title] Hemodialysis international. International Symposium on Home Hemodialysis
  • [ISO-abbreviation] Hemodial Int
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
  • [Chemical-registry-number] 9007-41-4 / C-Reactive Protein; EC 3.1.1.- / Carboxylic Ester Hydrolases; EC 3.1.1.2 / arylesterase; EC 3.1.8.1 / Aryldialkylphosphatase; EC 3.1.8.1 / PON1 protein, human
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37. Eissa S, Zohny SF, Swellam M, Mahmoud MH, El-Zayat TM, Salem AM: Comparison of CD44 and cytokeratin 20 mRNA in voided urine samples as diagnostic tools for bladder cancer. Clin Biochem; 2008 Nov;41(16-17):1335-41
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  • [MeSH-major] Antigens, CD44 / genetics. Antigens, CD44 / urine. Keratin-20 / genetics. Keratin-20 / urine. Urinary Bladder Neoplasms / diagnosis. Urinary Bladder Neoplasms / urine

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  • (PMID = 18804101.001).
  • [ISSN] 1873-2933
  • [Journal-full-title] Clinical biochemistry
  • [ISO-abbreviation] Clin. Biochem.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD44; 0 / Keratin-20; 0 / RNA, Messenger
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38. Helmy H, Weil GJ, Ellethy AS, Ahmed ES, Setouhy ME, Ramzy RM: Bancroftian filariasis: effect of repeated treatment with diethylcarbamazine and albendazole on microfilaraemia, antigenaemia and antifilarial antibodies. Trans R Soc Trop Med Hyg; 2006 Jul;100(7):656-62
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  • [Title] Bancroftian filariasis: effect of repeated treatment with diethylcarbamazine and albendazole on microfilaraemia, antigenaemia and antifilarial antibodies.
  • Diethylcarbamazine/albendazole (DEC/ALB) therapy is widely used in mass drug administration (MDA) programmes aimed at eliminating lymphatic filariasis.
  • We studied the effects of repeated annual treatments with DEC/ALB on Wuchereria bancrofti microfilaraemia, filarial antigenaemia and IgG4 antibodies to Bm14 antigen.
  • Fifty-seven subjects with asymptomatic microfilaraemia were treated with one or seven daily doses of DEC/ALB at time zero.
  • All subjects were re-treated with single-dose DEC/ALB 12, 24 and 36 months later.
  • The two treatment groups had comparable pre-treatment microfilaria counts.
  • Multidose treatment cleared microfilaraemia more effectively than single-dose treatment.
  • Filarial antigen levels decreased equally in both treatment groups.
  • Total antigen clearance was observed in 29.6%, 52.0%, 63.6% and 79.5% of subjects at 12, 24, 36 and 48 months.
  • These clearance rates are much higher than those observed in prior treatment trials with DEC or ivermectin.
  • Antibody levels increased 4 weeks after treatment and then slowly decreased in most subjects.
  • Antibody tests turned negative in 20%, 35%, 39.4% and 52.5% of treated subjects at 12, 24, 36 and 48 months post treatment.
  • These results show that the studied parameters decline at different rates and to differing degrees following DEC/ALB treatment.
  • These findings have important implications regarding strategies for monitoring the effects of MDA in populations.
  • [MeSH-major] Albendazole / administration & dosage. Anthelmintics / administration & dosage. Diethylcarbamazine / administration & dosage. Elephantiasis, Filarial / drug therapy
  • [MeSH-minor] Adolescent. Adult. Animals. Antibodies, Helminth / blood. Antigens, Helminth / blood. Drug Administration Schedule. Enzyme-Linked Immunosorbent Assay / methods. Female. Filaricides / administration & dosage. Humans. Immunoglobulin G / blood. Male. Microfilaria / isolation & purification. Treatment Outcome

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  • (PMID = 16414095.001).
  • [ISSN] 0035-9203
  • [Journal-full-title] Transactions of the Royal Society of Tropical Medicine and Hygiene
  • [ISO-abbreviation] Trans. R. Soc. Trop. Med. Hyg.
  • [Language] eng
  • [Grant] United States / NIAID NIH HHS / AI / AI 35855
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anthelmintics; 0 / Antibodies, Helminth; 0 / Antigens, Helminth; 0 / Filaricides; 0 / Immunoglobulin G; F4216019LN / Albendazole; V867Q8X3ZD / Diethylcarbamazine
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39. Dutta PK, Khan IH: Proliferative glomerulonephritis with acute renal failure-a rare manifestation in seronegative rheumatoid arthritis. Mymensingh Med J; 2009 Jan;18(1):84-7
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  • Acute interstitial nephritis (AIN) was excluded by absence of eosinophilia and eosinophils in urine.


40. Abdel-Shafi AA: Spectrophotometric determination of manganese by using redox reaction of tris(2,2'-bipyridine)osmium(II) with Mn7+. Anal Sci; 2006 Jun;22(6):825-8
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  • [Title] Spectrophotometric determination of manganese by using redox reaction of tris(2,2'-bipyridine)osmium(II) with Mn7+.
  • This paper reports on the analytical application of the oxidation reaction of [Os(bpy)3]2+ by Mn7+ (MnO4-).
  • The present study developed a very simple, sensitive and selective spectrophotometric method for the determination of manganese in an acidic medium.
  • Three analytical wavelengths were employed in the UV and visible regions at 290, 315 and 480 nm.
  • Beer's law was obeyed up to a concentration of 330 ng ml(-1) of Mn7+ at different wavelengths with regression equations 0.001 - 0.0042C(Mn), 0.001 + 0.0021C(Mn), and 0.001 - 9.34 x 10(-4)C(Mn) at 290, 315 and 480 nm, respectively.
  • Under the optimum conditions, the achieved detection limits were 0.72, 1.37 and 3.32 ng ml(-1) at 290, 315, and 480 nm, respectively.
  • In addition to the high sensitivity of the method (0.24 ng cm(-2) at 290 nm, 0.45 ng cm(-2) at 315 nm and 1.0 ng cm(-2) at 480 nm), it can be used for the determination of manganese in the presence of a large number of anions and cations, since it tolerates most of the potential interferents.
  • The relative standard deviation was 0.5% (n = 11) for 90 ng ml(-1) manganese.
  • The method was successfully applied to the determination of manganese in water from different resources.

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  • (PMID = 16772679.001).
  • [ISSN] 0910-6340
  • [Journal-full-title] Analytical sciences : the international journal of the Japan Society for Analytical Chemistry
  • [ISO-abbreviation] Anal Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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41. Klecha AJ, Salgueiro J, Wald M, Boccio J, Zubillaga M, Leonardi NM, Gorelik G, Cremaschi GA: In vivo iron and zinc deficiency diminished T- and B-selective mitogen stimulation of murine lymphoid cells through protein kinase C-mediated mechanism. Biol Trace Elem Res; 2005 May;104(2):173-83
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  • Mice from the BALB/c strain were fed with iron- and/or zinc-deficient or mineral-supplemented diets, according to the American Institute of Nutrition Rodent Diets.

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  • (PMID = 15894817.001).
  • [ISSN] 0163-4984
  • [Journal-full-title] Biological trace element research
  • [ISO-abbreviation] Biol Trace Elem Res
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Lipopolysaccharides; 0 / Phytohemagglutinins; 0 / Pokeweed Mitogens; 11028-71-0 / Concanavalin A; E1UOL152H7 / Iron; EC 2.7.11.13 / Protein Kinase C; J41CSQ7QDS / Zinc
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42. Sonnevend A, Rotimi VO, Kolodziejek J, Usmani A, Nowotny N, Pál T: High level of ciprofloxacin resistance and its molecular background among Campylobacter jejuni strains isolated in the United Arab Emirates. J Med Microbiol; 2006 Nov;55(Pt 11):1533-8
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  • The antibiotic sensitivity and the serotype and molecular type (MT) distribution of 41 Campylobacter jejuni strains isolated from individual patients in Tawam Hospital, Al Ain, United Arab Emirates, were investigated.

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  • (PMID = 17030913.001).
  • [ISSN] 0022-2615
  • [Journal-full-title] Journal of medical microbiology
  • [ISO-abbreviation] J. Med. Microbiol.
  • [Language] eng
  • [Databank-accession-numbers] GENBANK/ DQ449657/ DQ449658/ DQ449659/ DQ449660/ DQ449661/ DQ449662/ DQ449663/ DQ449664
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anti-Infective Agents; 0 / DNA, Bacterial; 5E8K9I0O4U / Ciprofloxacin; EC 5.99.1.3 / DNA Gyrase
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43. Tlili A, Dorigo U, Montuelle B, Margoum C, Carluer N, Gouy V, Bouchez A, Bérard A: Responses of chronically contaminated biofilms to short pulses of diuron. An experimental study simulating flooding events in a small river. Aquat Toxicol; 2008 May 30;87(4):252-63
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  • AFDW and chl ain vivo fluorescence increased in both microcosms during the experiment and biomass was higher in chronically exposed biofilms than in control ones.

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  • (PMID = 18387680.001).
  • [ISSN] 0166-445X
  • [Journal-full-title] Aquatic toxicology (Amsterdam, Netherlands)
  • [ISO-abbreviation] Aquat. Toxicol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Herbicides; 0 / Pigments, Biological; 0 / RNA, Bacterial; 0 / RNA, Ribosomal, 16S; 0 / RNA, Ribosomal, 18S; 0 / Water Pollutants, Chemical; 7440-44-0 / Carbon; 9I3SDS92WY / Diuron
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44. Reeves PG, DeMars LC: Signs of iron deficiency in copper-deficient rats are not affected by iron supplements administered by diet or by injection. J Nutr Biochem; 2006 Sep;17(9):635-42
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  • In Experiment 1, weanling male Sprague-Dawley rats were fed AIN-93G diets containing either <0.3 mg Cu [Cu deficient (CuD)] or 6.0 mg Cu [Cu adequate (CuA)] per kilogram diet, and 35 mg Fe/kg.

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  • (PMID = 16781861.001).
  • [ISSN] 0955-2863
  • [Journal-full-title] The Journal of nutritional biochemistry
  • [ISO-abbreviation] J. Nutr. Biochem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 789U1901C5 / Copper; E1UOL152H7 / Iron; EC 1.4.- / ceruloplasmin amine oxidase; EC 1.5.- / Oxidoreductases Acting on CH-NH Group Donors
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45. Montasser AA: The fowl tick, Argas (Persicargas) persicus (Ixodoidea: Argasidae): description of the egg and redescription of the larva by scanning electron microscopy. Exp Appl Acarol; 2010 Dec;52(4):343-61
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  • [Title] The fowl tick, Argas (Persicargas) persicus (Ixodoidea: Argasidae): description of the egg and redescription of the larva by scanning electron microscopy.
  • This scanning electron microscopy study revealed that the egg of Argas persicus was covered with chorion which appeared as a wrinkled layer containing regions of three textures.
  • The first had elevated parts of slightly rough surface.
  • The second had irregular smooth elevations; each carried numerous parallel horizontal foldings with vertical ridges.
  • The last region had rough surface with irregularly shaped projections.
  • Following the removal of the chorion, shell was observed to have one polar micropyle and numerous slit like openings.
  • Length (L), width (W) and L/W ratio of the egg were measured.
  • Investigation of larvae revealed extensively folded integument of idiosoma and spherical or elongated tubercles on dorsal plate.
  • Mouth enclosed between ventral hypostome and two dorsal chelicerae.
  • Hypostome carried four longitudinal rows of conical denticles.
  • Each chelicera was made up of two segments; the basal one appeared as a pocket for the distal one.
  • Haller's organ consisted of an anterior pit containing seven sensilla and a posterior capsule with four apertures.
  • Distribution of chemo- and mechano-sensilla on the body was examined.
  • Measurements of whole body, idiosoma, dorsal plate, capitulum, hypostome, palp and different types of sensilla both on the body and Haller's organ are also presented.
  • [MeSH-major] Argas / ultrastructure. Ovum / ultrastructure
  • [MeSH-minor] Animals. Female. Larva / ultrastructure. Microscopy, Electron, Scanning. Surface Properties

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  • (PMID = 20607364.001).
  • [ISSN] 1572-9702
  • [Journal-full-title] Experimental & applied acarology
  • [ISO-abbreviation] Exp. Appl. Acarol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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46. Hume AN, Buttgereit J, Al-Awadhi AM, Al-Suwaidi SS, John A, Bader M, Seabra MC, Al-Gazali L, Ali BR: Defective cellular trafficking of missense NPR-B mutants is the major mechanism underlying acromesomelic dysplasia-type Maroteaux. Hum Mol Genet; 2009 Jan 15;18(2):267-77
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  • [Title] Defective cellular trafficking of missense NPR-B mutants is the major mechanism underlying acromesomelic dysplasia-type Maroteaux.
  • Mutations in NPR-B have been shown to cause acromesomelic dysplasia-type Maroteaux (AMDM), a growth disorder in humans and severe dwarfism in mice.


47. Baumgardner JN, Shankar K, Hennings L, Albano E, Badger TM, Ronis MJ: N-acetylcysteine attenuates progression of liver pathology in a rat model of nonalcoholic steatohepatitis. J Nutr; 2008 Oct;138(10):1872-9
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  • We examined the effects of NAC in a rat total enteral nutrition (TEN) model where NASH develops as the result of overfeeding dietary polyunsaturated fat.
  • Male Sprague-Dawley rats consumed pelleted AIN-93G diets ad libitum or were overfed a 9200 kJ.kg(-0.75).d(-1) liquid diet containing 70% corn oil with or without 2 g.kg(-1).d(-1) NAC i.g. for 65 d.

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  • (PMID = 18806095.001).
  • [ISSN] 1541-6100
  • [Journal-full-title] The Journal of nutrition
  • [ISO-abbreviation] J. Nutr.
  • [Language] ENG
  • [Grant] United States / NIAAA NIH HHS / AA / AA012819-05; United States / NIAAA NIH HHS / AA / R01 AA012819; United States / NIAAA NIH HHS / AA / R01 AA012819-05; United States / NIAAA NIH HHS / AA / R01 AA 12819; United States / NIAAA NIH HHS / AA / R01 AA018282
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Autoantibodies; 0 / Triglycerides; GAN16C9B8O / Glutathione; WYQ7N0BPYC / Acetylcysteine
  • [Other-IDs] NLM/ NIHMS232260; NLM/ PMC2935161
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48. Kreuter A, Potthoff A, Brockmeyer NH, Gambichler T, Stücker M, Altmeyer P, Swoboda J, Pfister H, Wieland U, German Competence Network HIV/AIDS: Imiquimod leads to a decrease of human papillomavirus DNA and to a sustained clearance of anal intraepithelial neoplasia in HIV-infected men. J Invest Dermatol; 2008 Aug;128(8):2078-83
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  • [Title] Imiquimod leads to a decrease of human papillomavirus DNA and to a sustained clearance of anal intraepithelial neoplasia in HIV-infected men.
  • Anal intraepithelial neoplasia (AIN), a human papillomavirus (HPV)-associated precursor lesion of anal carcinoma, is highly prevalent in HIV-infected men having sex with men (MSM).
  • This prospective follow-up study evaluated the long-term results of imiquimod treatment of AIN in 19 HIV-infected MSM.
  • Standardized follow-up examinations included high-resolution anoscopy, anal cytology/histology, HPV typing, and DNA load determination for HPV types 16, 18, 31, and 33.
  • A total of 74% (14/19) of the patients remained free of AIN at the previously treated site.
  • Five patients (26%) had recurrent high-grade AIN after a mean time of 24.6 months.
  • During follow-up, 58% of all patients (11/19) developed new anal cytological abnormalities in previously normal, untreated anal regions.
  • 55% of these new AIN lesions were high-grade lesions and most of them were located intra-anally and associated with high-risk HPV types not detectable before therapy.
  • These results demonstrate that imiquimod leads to a high rate of long-term clearance of AIN in HIV-positive men together with a prolonged decrease of high-risk HPV-DNA load.
  • However, new AIN lesions associated with previously undetected HPV types frequently occur in untreated areas.
  • [MeSH-major] Aminoquinolines / therapeutic use. Antineoplastic Agents / therapeutic use. Anus Neoplasms / drug therapy. Carcinoma in Situ / drug therapy. DNA, Viral / drug effects. HIV Infections / complications. Papillomaviridae / genetics

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  • (PMID = 18273049.001).
  • [ISSN] 1523-1747
  • [Journal-full-title] The Journal of investigative dermatology
  • [ISO-abbreviation] J. Invest. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Aminoquinolines; 0 / Antineoplastic Agents; 0 / DNA, Viral; 99011-02-6 / imiquimod
  • [Investigator] Adam A; Schewe K; Weitner L; Aratesh K; Arendt G; Bartz C; Behrens G; Beichert M; Bieniek B; Cordes C; Bochow M; Brockmeyer N; Buchholz B; Bogner JR; Buhk T; Clad A; Dannecker M; Dupke S; von Einsiedel R; Esser S; Faetkenheuer G; Fischer K; Freiwald M; Friebe-Hoffmann U; Fenske S; Funk M; Ganschow R; Gingelmaier A; Glaunsinger T; Goebel FD; Gölz J; Grosch-Wörner I; Haberl A; Hamouda O; Harrer T; Hartmann M; Hartl H; Hölscher M; Hower M; Husstedt IW; Jansen K; Jäger H; Jessen H; Jessen A; Karwat M; Klausen G; Kirchhoff F; Knechten H; Köppe S; Kreuter A; Kuhlmann B; Langer P; Lauenroth-Mai; Lehmacher W; Lehmann M; Levin C; Lübke M; Maschke M; Marcus U; Mauss S; Meyerhans A; Meyer-Olson D; ter Meulen V; Michalik C; Moll A; Mosthaf FA; Mutz A; Neuen-Jacob E; Niehues T; Oette M; Paulus U; Plettenberg A; Potthoff A; Racz P; Racz K; Rasokat H; Rausch M; Reichelt D; Reitter A; Rieke A; Rockstroh J; Salzberger B; Schafberger A; Schauer J; Schlote F; Schmidt B; Schranz D; Scholten S; Schuler C; Schwab M; Schmidt W; Schmidt R; Schwarze S; Siffert W; Skaletz-Rorowski A; Sonnenberg-Schwan U; Sopper S; Spengler U; Staszewski S; Steffan E; Stellbrink HJ; Stoll M; Goecke T; Taubert S; Telschik A; Ulmer A; Ullrich R; Uberla K; Usadel S; Vogel M; Wagner R; Walter H; Warnatz K; Wasem J; Wiesel W; Von Weizsäcker K; Wieland U; Wintergerst U; Wolf E; Wolf H; Wünsche T; Wyen Ch; Zeitz M; Zylka-Menhorn V
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49. Ibrahim WH, Habib HM, Chow CK, Bruckner GG: Isoflavone-rich soy isolate reduces lipid peroxidation in mouse liver. Int J Vitam Nutr Res; 2008 Jul-Sep;78(4-5):217-22
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  • Weanling C57BL6 male mice were fed a basal diet (AIN-93G) supplemented with either nothing or 1.08 gram isoflavone-rich soy isolate/kg diet for 60 days.

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  • (PMID = 19326345.001).
  • [ISSN] 0300-9831
  • [Journal-full-title] International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition
  • [ISO-abbreviation] Int J Vitam Nutr Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Alkadienes; 0 / Antioxidants; 0 / Isoflavones; 0 / Plant Extracts; 0 / Soybean Proteins; 4Y8F71G49Q / Malondialdehyde; 6287WC5J2L / daidzein; DH2M523P0H / Genistein; EC 1.11.1.6 / Catalase; EC 1.11.1.9 / Glutathione Peroxidase; EC 1.15.1.1 / Superoxide Dismutase; GAN16C9B8O / Glutathione; H4N855PNZ1 / alpha-Tocopherol; PQ6CK8PD0R / Ascorbic Acid
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50. Barve A, Khor TO, Reuhl K, Reddy B, Newmark H, Kong AN: Mixed tocotrienols inhibit prostate carcinogenesis in TRAMP mice. Nutr Cancer; 2010;62(6):789-94
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  • Male TRAMP mice, 8 wk old, were fed 0.1%, 0.3%, or 1% mixed tocotrienols in AIN-76A diet up to 24 wk old.
  • Likewise, a positive control group consisting of male TRAMP mice and a negative control group consisting of wild-type nontransgenic mice were fed regular AIN-76A diet up to 24 wk old.

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  • (PMID = 20661828.001).
  • [ISSN] 1532-7914
  • [Journal-full-title] Nutrition and cancer
  • [ISO-abbreviation] Nutr Cancer
  • [Language] eng
  • [Grant] United States / NIEHS NIH HHS / ES / P30 ES005022
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anticarcinogenic Agents; 0 / Tocotrienols
  • [Other-IDs] NLM/ NIHMS745944; NLM/ PMC4699666
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51. Reen RK, Nines R, Stoner GD: Modulation of N-nitrosomethylbenzylamine metabolism by black raspberries in the esophagus and liver of Fischer 344 rats. Nutr Cancer; 2006;54(1):47-57
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  • [Title] Modulation of N-nitrosomethylbenzylamine metabolism by black raspberries in the esophagus and liver of Fischer 344 rats.
  • To determine the mechanistic basis of the anti-initiating effects of BRBs, NMBA metabolism was studied in esophageal explant cultures and in liver microsomes taken from rats fed with AIN-76A diet or AIN-76A diet containing 5% or 10% BRBs.

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  • (PMID = 16800772.001).
  • [ISSN] 0163-5581
  • [Journal-full-title] Nutrition and cancer
  • [ISO-abbreviation] Nutr Cancer
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA103180-03; United States / NCI NIH HHS / CA / R01 CA103180; United States / NCI NIH HHS / CA / CA 103180; United States / NCI NIH HHS / CA / R01 CA103180-03
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Carcinogens; 0 / Isothiocyanates; 6U7TFK75KV / phenethyl isothiocyanate; 937-40-6 / nitrosobenzylmethylamine; EC 2.5.1.18 / Glutathione Transferase; M43H21IO8R / Dimethylnitrosamine
  • [Other-IDs] NLM/ NIHMS258994; NLM/ PMC3015089
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52. Bu SY, Lucas EA, Franklin M, Marlow D, Brackett DJ, Boldrin EA, Devareddy L, Arjmandi BH, Smith BJ: Comparison of dried plum supplementation and intermittent PTH in restoring bone in osteopenic orchidectomized rats. Osteoporos Int; 2007 Jul;18(7):931-42
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  • The ORX groups were assigned to control (AIN-93M) diet, 25% DP diet, or PTH (80 microg/kg) for 90 days.

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  • (PMID = 17554580.001).
  • [ISSN] 0937-941X
  • [Journal-full-title] Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
  • [ISO-abbreviation] Osteoporos Int
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Parathyroid Hormone
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53. Al-Akhras M: A new application of Gompertz function in photohemolysis: the effect of temperature on red blood cell hemolysis photosensitized by protoporphyrin IX. Med Biol Eng Comput; 2006 Aug;44(8):703-10
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  • [Title] A new application of Gompertz function in photohemolysis: the effect of temperature on red blood cell hemolysis photosensitized by protoporphyrin IX.
  • Photosensitization by protoporphyrin IX (PpIX) is accelerated at different irradiation temperatures, different dark incubation temperatures (Tinc) and different irradiation times.
  • The applicability of Gompertz function to the fractional photohemolysis ratio, a and the rate of fractional photohemolysis, b is found to be the most appropriate model to fit the experimental data with minimum parameters and minimum errors.
  • The reduction in Gompertz parameters, the fractional ratio values of a, and increase in the fractional rate values b, for 20 microM PpIX irradiated with black light at low irradiation temperature 5 degrees C and higher Tinc 37 degrees C was noticed.
  • The parameter a has higher values at lower irradiation time and lower irradiation temperatures which indicates a longer photohemolysis process and longer t 50.
  • Values of the parameter b were found to be strongly temperature-dependent, and always increase with increasing irradiation time and Tinc with lower values at lower irradiation time and lower Tinc.
  • There are no significant changes in the lysis of RBCs process at irradiation temperatures equal to or higher than 35 degrees C.
  • Similarly, no significant change on t50 at higher irradiation time at Tinc 24 and 37 degrees C.
  • In conclusion, Gompertz analysis technique adapts to study the photohemolysis process at different conditions as a best-fit model.
  • [MeSH-major] Erythrocytes / drug effects. Hemolysis / drug effects. Photosensitizing Agents / pharmacology. Protoporphyrins / pharmacology
  • [MeSH-minor] Animals. Cats. Light. Mathematics. Temperature. Time Factors

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  • (PMID = 16937212.001).
  • [ISSN] 0140-0118
  • [Journal-full-title] Medical & biological engineering & computing
  • [ISO-abbreviation] Med Biol Eng Comput
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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54. Clark RM, Balakrishnan A, Waters D, Aggarwal D, Owen KQ, Koo SI: L-carnitine increases liver alpha-tocopherol and lowers liver and plasma triglycerides in aging ovariectomized rats. J Nutr Biochem; 2007 Sep;18(9):623-8
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  • Seven rats per treatment were assigned to either a control group fed ad libitum AIN-93M diet or a carnitine group fed the same diet supplemented with L-carnitine.

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  • (PMID = 17368883.001).
  • [ISSN] 0955-2863
  • [Journal-full-title] The Journal of nutritional biochemistry
  • [ISO-abbreviation] J. Nutr. Biochem.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Triglycerides; H4N855PNZ1 / alpha-Tocopherol; S7UI8SM58A / Carnitine
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55. Nabhan AF, Faris MA: High feedback versus low feedback of prenatal ultrasound for reducing maternal anxiety and improving maternal health behaviour in pregnancy. Cochrane Database Syst Rev; 2010;(4):CD007208
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  • BACKGROUND: Prenatal ultrasound is one of many techniques used in screening and diagnosis.

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  • [UpdateIn] Cochrane Database Syst Rev. 2015;8:CD007208 [26241793.001]
  • (PMID = 20393957.001).
  • [ISSN] 1469-493X
  • [Journal-full-title] The Cochrane database of systematic reviews
  • [ISO-abbreviation] Cochrane Database Syst Rev
  • [Language] eng
  • [Publication-type] Journal Article; Meta-Analysis; Review
  • [Publication-country] England
  • [Number-of-references] 32
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56. Karam SM: Mouse models demonstrating the role of stem/progenitor cells in gastric carcinogenesis. Front Biosci (Landmark Ed); 2010;15:595-603
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  • Advances have been made in identifying the gastric epithelial stem cells and their immediate descendents which act as uncommitted or committed progenitors giving rise to cell lineages producing the various contents of the gastric juice and several hormones.
  • New research suggests that these epithelial stem/progenitor cells also play an important role in the development of gastric cancer.

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  • (PMID = 20036835.001).
  • [ISSN] 1093-4715
  • [Journal-full-title] Frontiers in bioscience (Landmark edition)
  • [ISO-abbreviation] Front Biosci (Landmark Ed)
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Diphtheria Toxin; 0 / Peptides; 0 / Tff1 protein, mouse
  • [Number-of-references] 45
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57. Hassan SS, Badr IH, Kamel AH, Mohamed MS: A novel poly(vinyl chloride) matrix membrane sensor for batch and flow-injection determinations of thiocyanate, cyanide and some metal ions. Anal Sci; 2009 Jul;25(7):911-7
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  • [Title] A novel poly(vinyl chloride) matrix membrane sensor for batch and flow-injection determinations of thiocyanate, cyanide and some metal ions.
  • A poly(vinyl chloride) matrix membrane sensor for the selective determination of thiocyanate has been developed based on the use of copper(II)-2-(5-bromo-2-pyridylazo)-5-diethylaminophenol complex (Cu-PADAP) as a novel charged carrier, and o-nitrophenyloctyl ether (o-NPOE) as a solvent mediator.
  • The sensor displays a significantly enhanced response towards SCN(-) ions over the concentration range 7.0 x 10(-6) to 1.0 x 10(-2) mol L(-1) with a detection limit of 5.6 x 10(-6) mol L(-1) and a calibration slope of -57.5 +/- 0.5 mV decade(-1).
  • The sensor exhibits a long life-span, long-term stability, high reproducibility, and a fast response time.
  • The selectivity coefficients of some anions were calculated using the separate solutions method, and found to be in the following order: SCN(-) > ClO(4)(-) > I(-) > Sal(-) > NO(2)(-) > Br(-) > NO(3)(-) = CH(3)COO(-) > Cl(-) > SO(4)(2-) = PO(4)(3-).
  • The effects of the pH and ionic membrane additives (e.g. tridodecylmethylammonium chloride, TDMAC and potassium tetrakis[bis(3,5-trifluoromethyl)phenyl] borate, KTFPB) were examined.
  • The sensor was used for the determination of SCN(-) ions in saliva and urine samples collected from some smoker and non-smoker donors.
  • The developed sensor was also applied to determine the cyanide content in electroplating waste water samples after its conversion into thiocyanate.
  • The application of the sensor to monitor the potentiometric titration of Ag(+) and Hg(2+) using SCN(-) resulted in sharp inflection breaks at the equivalent points.
  • The data obtained using the proposed sensor correlate very well with results collected using the standard methods of thiocyanate, cyanide and metal analysis.
  • [MeSH-major] Chemistry, Analytic / instrumentation. Cyanides / analysis. Membranes, Artificial. Metals / analysis. Polyvinyl Chloride / chemistry. Thiocyanates / analysis
  • [MeSH-minor] Adult. Aged. Flow Injection Analysis. Humans. Middle Aged. Organometallic Compounds / chemistry. Potentiometry. Saliva / chemistry. Time Factors

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  • (PMID = 19609032.001).
  • [ISSN] 1348-2246
  • [Journal-full-title] Analytical sciences : the international journal of the Japan Society for Analytical Chemistry
  • [ISO-abbreviation] Anal Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Cyanides; 0 / Membranes, Artificial; 0 / Metals; 0 / Organometallic Compounds; 0 / Thiocyanates; 302-04-5 / thiocyanate; 9002-86-2 / Polyvinyl Chloride
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58. Al-Salam S, Nowotny N, Sohail MR, Kolodziejek J, Berger TG: Ecthyma contagiosum (orf)--report of a human case from the United Arab Emirates and review of the literature. J Cutan Pathol; 2008 Jun;35(6):603-7
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  • [Title] Ecthyma contagiosum (orf)--report of a human case from the United Arab Emirates and review of the literature.
  • BACKGROUND: Ecthyma contagiosum (orf) is caused by an epitheliotropic parapox virus.
  • It is a zoonosis usually transmitted to humans from affected sheep or goat through direct contact or contaminated fomites.
  • METHODS: We report a 36-year-old patient with multiple skin lesions on his left hand, first observed 5 days before admission followed by red streaks on the forearm and an erythema on the upper arm 1 day prior to admission.
  • The patient reported that he was working on a sheep farm.
  • RESULTS: Histopathologic examination showed evidence of a viral infection.
  • Subsequent transmission electron microscopy showed typical parapox virus particles, predominantly in the scaled-off layers of degenerated keratinocytes and monocytes.
  • The results were verified and specified by two newly established polymerase chain reaction (PCR) assays and subsequent sequencing of the amplicons: one broadly reacting 'general parapox virus PCR', and one assay which allows--following sequencing--discrimination between individual orf virus strains.
  • CONCLUSION: Despite the multiplicity of the lesions, there was a significant improvement after 2 weeks of treatment.
  • Sequencing showed the uniqueness of this virus compared with previously published strains from other countries.
  • [MeSH-major] Ecthyma, Contagious / transmission. Poxviridae / isolation & purification. Sheep / virology. Sheep Diseases / transmission. Skin Diseases, Infectious / transmission. Zoonoses
  • [MeSH-minor] Adult. Animals. Base Sequence. DNA, Viral / analysis. Humans. Keratinocytes / ultrastructure. Keratinocytes / virology. Male. Molecular Sequence Data. Monocytes / ultrastructure. Monocytes / virology. RNA, Viral / analysis. Sequence Analysis, DNA. United Arab Emirates

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  • (PMID = 18201239.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / DNA, Viral; 0 / RNA, Viral
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59. Nassar WA, Bassiony AA, Elghazaly HA: Treatment of diffuse pigmented villonodular synovitis of the knee with combined surgical and radiosynovectomy. HSS J; 2009 Feb;5(1):19-23
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  • Post-synovectomy adjuvant treatment with external beam radiation therapy or intra-articular injection of radioactive material as yttrium-90 ((90)Y) yielded better results.

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  • (PMID = 19096892.001).
  • [ISSN] 1556-3316
  • [Journal-full-title] HSS journal : the musculoskeletal journal of Hospital for Special Surgery
  • [ISO-abbreviation] HSS J
  • [Language] eng
  • [Publication-type] Journal Article
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60. Ain MC, Abdullah MA, Ting BL, Skolasky RL, Carlisle ES, Schkrohowsky JG, Rigamonti D: Progression of low back and lower extremity pain in a cohort of patients with achondroplasia. J Neurosurg Spine; 2010 Sep;13(3):335-40
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  • [Title] Progression of low back and lower extremity pain in a cohort of patients with achondroplasia.
  • OBJECT: The aim of this study was to assess the natural history of pain associated with spinal stenosis in individuals with achondroplasia and to characterize pain patterns and associated functional and psychological effects.
  • METHODS: The authors measured pain severity, spatial distribution of pain, functional disability, psychological distress, physical symptoms other than pain, and healthcare utilization in 181 individuals with achondroplasia.
  • They also assessed low back and/or lower extremity pain at the initial visit and 1-year follow-up via self-rated patient questionnaires, calculated composite scores from responses via component analyses, and used repeated measures linear regression analyses for score changes (significance, p < or = 0.05).
  • RESULTS: At the follow-up, back pain severity was unchanged.
  • Patients reported significant progression of pain toward involvement of the lower extremities and significant increases in lower extremity pain severity overall.
  • There were also significant increases in healthcare utilization overall.
  • Compared with patients with back pain only, those with back pain and proximal or distal leg pain had higher self-rated pain severity; higher functional disability; and more bowel and bladder dysfunction symptoms, sleep disturbances, extremity numbness, and psychological distress.
  • CONCLUSIONS: Individuals with achondroplasia and symptomatic spinal stenosis often experience back pain, which may progress to lower extremity pain and debilitating consequences.
  • A more thorough understanding of the progression of spatial pain characteristics and pain severity may aid clinical decision making regarding the optimal timing for intervention.
  • [MeSH-major] Achondroplasia / physiopathology. Leg. Low Back Pain / physiopathology. Pain / physiopathology
  • [MeSH-minor] Adolescent. Adult. Aged. Cohort Studies. Disability Evaluation. Disease Progression. Female. Follow-Up Studies. Humans. Linear Models. Male. Middle Aged. Patient Acceptance of Health Care. Severity of Illness Index. Spinal Stenosis / complications. Spinal Stenosis / physiopathology. Spinal Stenosis / psychology. Surveys and Questionnaires. Young Adult

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  • (PMID = 20809726.001).
  • [ISSN] 1547-5646
  • [Journal-full-title] Journal of neurosurgery. Spine
  • [ISO-abbreviation] J Neurosurg Spine
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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61. Asfour IA, Elshazly SA: Changing therapy from Glivecto a "copy" imatinib results in a worsening of chronic myeloid leukemia disease status: two case reports. Cases J; 2009;2:9342
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  • [Title] Changing therapy from Glivecto a "copy" imatinib results in a worsening of chronic myeloid leukemia disease status: two case reports.
  • INTRODUCTION: Imatinib mesylate (Glivec((R))/Gleevec((R))) is the standard first-line therapy for the treatment of chronic myeloid leukemia due to its high hematologic, cytogenetic, and molecular response rates and favorable long-term safety profile.
  • A copy version of imatinib is currently available in several countries.
  • We report on two cases of CML who were originally treated with Glivec in Egypt and subsequently switched to the copy drug CASE PRESENTATION: Case one was a 35-year old female with chronic myeloid leukemia in blast crisis who began treatment with combination chemotherapy and Glivec.
  • The patient achieved and maintained a complete hematologic response and continued on Glivec 400 mg/day.
  • In March 2007, she was switched to the copy drug In September 2007, the patient presented in hematologic relapse.
  • At this time, treatment with chemotherapy in combination with Glivec 400 mg/day was resumed.
  • The patient quickly achieved, and maintained, complete hematologic response on Glivec 400 mg/day.
  • The second patient was a 64-year old male with chronic myeloid leukemia in blast crisis who began treatment with truncated chemotherapy in combination with Glivec 400 mg/day.
  • After 6 months, the patient achieved a partial hematologic response and continued on alternating cycles of chemotherapy with continuous administration of Glivec 400 mg/day.
  • The patient received Glivec from January 2006 to February 2007, after which time he was switched to the copy drug.
  • In November 2007, he presented with upper gastrointestinal bleeding and multiple gastric erosions and died the same day.
  • CONCLUSION: The safety and efficacy of the copy drug has not been established in randomized clinical trials.
  • It is unknown whether patients, who respond to Glivec and then switch to copy versions of imatinib, will tolerate the copy drug and maintain their response.

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  • (PMID = 20062598.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2803998
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62. El-Demerdash E, Salam OM, El-Batran SA, Abdallah HM, Shaffie NM: Inhibition of the renin-angiotensin system attenuates the development of liver fibrosis and oxidative stress in rats. Clin Exp Pharmacol Physiol; 2008 Feb;35(2):159-67
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  • [Title] Inhibition of the renin-angiotensin system attenuates the development of liver fibrosis and oxidative stress in rats.
  • 1. The present study was designed to investigate the potential antifibrotic and anti-oxidant effects of lisinopril, fosinopril and losartan in an experimental rat model of liver injury using carbon tetrachloride (CCl(4)).
  • 2. First, the potential hepatoprotective dose of each drug was screened against CCl(4)-induced acute hepatotoxicity.
  • Then, we chose the minimum hepatoprotective dose of each drug to further investigate the mechanisms involved in the hepatoprotection using a chronic model of hepatotoxicity induced by CCl(4).
  • 3. Liver function was assessed in addition to histopathological examination.
  • Furthermore, oxidative stress markers (reduced glutathione (GSH) and lipid peroxides levels) and markers of fibrosis (hydroxyproline content and liver fibrosis area) were assessed.
  • 4. It was found that treatment of animals with different drugs concomitantly with CCl(4) significantly counteracted the changes in liver function induced by CCl(4) (except fosinopril).
  • In addition, the drugs ameliorated the histopathological changes induced by CCl(4).
  • All drugs significantly counteracted lipid peroxidation and GSH depletion (except fosinopril) compared with the CCl(4)-intoxicated group.
  • Moreover, the drugs studied significantly reduced liver hydroxyproline levels and the area of fibrosis compared with the CCl(4)-intoxicated group.
  • 5. In conclusion, the present study provides evidence for the hepatoprotective effect of lisinopril, fosinopril and losartan.
  • Both lisinopril and losartan was found to have better hepatoprotective potential than fosinopril against CCl(4)-induced hepatotoxicity.
  • These hepatoprotective effects can be explained on the basis of anti-oxidant and antifibrotic mechanisms, mainly enhancement of GSH and reduction of lipid peroxidation and fibrosis.
  • [MeSH-major] Angiotensin II Type 1 Receptor Blockers / pharmacology. Angiotensin-Converting Enzyme Inhibitors / pharmacology. Antioxidants / pharmacology. Liver / drug effects. Liver Cirrhosis / prevention & control. Oxidative Stress / drug effects. Renin-Angiotensin System / drug effects
  • [MeSH-minor] Animals. Carbon Tetrachloride. Disease Models, Animal. Dose-Response Relationship, Drug. Fosinopril / pharmacology. Glutathione / metabolism. Hydroxyproline / metabolism. Lipid Peroxidation / drug effects. Lisinopril / pharmacology. Liver Function Tests. Losartan / pharmacology. Male. Rats

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  • (PMID = 17900296.001).
  • [ISSN] 1440-1681
  • [Journal-full-title] Clinical and experimental pharmacology & physiology
  • [ISO-abbreviation] Clin. Exp. Pharmacol. Physiol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Angiotensin II Type 1 Receptor Blockers; 0 / Angiotensin-Converting Enzyme Inhibitors; 0 / Antioxidants; CL2T97X0V0 / Carbon Tetrachloride; E7199S1YWR / Lisinopril; GAN16C9B8O / Glutathione; JMS50MPO89 / Losartan; R43D2573WO / Fosinopril; RMB44WO89X / Hydroxyproline
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63. Padmanabhan R, Al-Menhali NM, Ahmed I, Kataya HH, Ayoub MA: Histological, histochemical and electron microscopic changes of the placenta induced by maternal exposure to hyperthermia in the rat. Int J Hyperthermia; 2005 Feb;21(1):29-44
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  • [Title] Histological, histochemical and electron microscopic changes of the placenta induced by maternal exposure to hyperthermia in the rat.
  • Both clinical and experimental investigations have shown that maternal hyperthermia during critical stages of embryo development can induce malformations in the offspring.
  • Studies of the effect of heat stress on the placental functions are limited to the ewes, but that on microscopic structure is unknown.
  • In the present study, rats were exposed to 41 or 42 degrees C for 1 h on gestation day (GD) 9.
  • The controls were sham treated.
  • Fetuses and placentas were collected on GD 20.
  • Intrauterine growth retardation (IUGR) and several craniofacial malformations were observed in the fetuses of the heat-treated group.
  • The placentas of the 42 degrees C group were significantly lighter in weight than those of the control.
  • Light microscopy (LM) revealed thickening, hyalinization and occasional lymphocytic infiltration of the decidua basalis.
  • Giant cells were prominent and glycogen cells had degenerated, leaving behind large cysts in the basal (spongy) zone.
  • Best's carmine stain with or without diastase indicated the reduction in number and degeneration of glycogen cells and cyst formation.
  • The labyrinthine zone was relatively thin in comparison to that of the controls.
  • Perivascular fibrosis and paucity of vascularization were other features of the placentas of the hyperthermia group.
  • Electron microscopy (EM) revealed lipid droplet accumulation in the trophoblast, the presence of myelin bodies and an increased production of collagen in the basal zone.
  • Perivascular fibrosis appeared to have contributed to placental barrier thickening.
  • EM also revealed accumulation of glycogen and lipid droplets in the trophoblasts and fibrin secretion into the extracellular space of the labyrinthine zone.
  • These data suggest that placental pathology possibly contributes to fetal growth retardation in maternally heat-stressed rat fetuses.
  • [MeSH-major] Fetal Growth Retardation / pathology. Fever / pathology. Placenta / pathology
  • [MeSH-minor] Animals. Craniofacial Abnormalities / etiology. Craniofacial Abnormalities / pathology. Environmental Exposure. Female. Fetus / pathology. Fibrosis. Microscopy, Electron. Pregnancy. Rats. Rats, Wistar. Stress, Physiological / pathology

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  • (PMID = 15764349.001).
  • [ISSN] 0265-6736
  • [Journal-full-title] International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
  • [ISO-abbreviation] Int J Hyperthermia
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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64. El-Sayed ZA, Ragab SM, Khalifa KA, El Ashmawy RA: Altered CD19/CD22 balance in Egyptian children and adolescents with systemic lupus erythematosus. Egypt J Immunol; 2009;16(1):27-38
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  • [Title] Altered CD19/CD22 balance in Egyptian children and adolescents with systemic lupus erythematosus.
  • B cells from systemic lupus erythematosus (SLE) patients display signalling defects that may underlie disease pathogenesis activity.CD19 and CD22 play a major role as regulators of B-cell response.
  • The aim of this study was to clarify the relationship between B cell surface markers namely CD19, CD20 and CD22 expression and clinical and laboratory indices of SLE activity.
  • The study included 33 SLE patients and 20 healthy children and adolescents as controls.
  • Flowcytometric assay of dual markers, CD19/CD20, and CD20/CD22 was done.
  • SLE disease activity was assessed by SLEDAI score.
  • CD22% was significantly higher while CD20% was significantly lower in the study compared to the control group.
  • No significant difference was observed in both groups with respect to CD19% or CD19/CD22% ratio.
  • The level of CD22 expression was significantly lower in high and very high active cases than in mild and moderate cases and negatively correlated with SLDEAI score and ESR.
  • Results obtained showed that, B cell surface receptors CD20 and CD22 are significantly affected in patients with SLE, pointing to their possible involvement in the aetiopathogenesis of the disease and in the regulatory mechanisms in response to the immune disturbance.

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  • (PMID = 20726320.001).
  • [ISSN] 1110-4902
  • [Journal-full-title] The Egyptian journal of immunology
  • [ISO-abbreviation] Egypt J Immunol
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
  • [Chemical-registry-number] 0 / Antigens, CD19; 0 / Antigens, CD20; 0 / CD22 protein, human; 0 / Sialic Acid Binding Ig-like Lectin 2
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65. Mousa AS: Preliminary evaluation of nonpenetrating deep sclerectomy with autologous scleral implant in open-angle glaucoma. Eye (Lond); 2007 Sep;21(9):1234-8
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  • [Title] Preliminary evaluation of nonpenetrating deep sclerectomy with autologous scleral implant in open-angle glaucoma.
  • AIM: The aim of this study is to evaluate the short-term result of the use of an autologous scleral implant during the nonpenetrating deep sclerectomy operation instead of the more expensive collagen implant.
  • DESIGN: Prospective nonrandomized pilot study.
  • PATIENTS AND METHODS: This study included 20 eyes of 20 patients with a mean age of 42.3+/-8.1 years and the mean of preoperative best-corrected visual acuity was 0.66+/-6.2.
  • All patients were indicated for conventional deep sclerectomy operation but with implantation of an autologous scleral implant.
  • The operation was considered completely successful if the intraocular pressure (IOP) is below 18 mmHg without medications while qualified success was considered if the IOP was below 18 mmHg with medications.
  • RESULTS: This technique succeeded in declining the mean IOP from 33.1+/-6.2 mmHg preoperatively to 14.6+/-3.8 mmHg postoperatively by the end of the follow-up period (12 months).
  • Complete and qualified successful results were seen in 85% of cases.
  • Nd:YAG goniopuncture was needed in 45% of the cases.
  • This intervention was needed 14.0+/-10.0 weeks postoperatively.
  • The study group showed low incidence of postoperative complication with statistically nonsignificant effect on the postoperative visual acuity.
  • CONCLUSION: The use of autologous scleral implant can be of value in controlling the IOP with low cost to the patient.
  • Nd:YAG goniopuncture is to be performed around the third month postoperatively in cases with advanced glaucomatous changes to avoid the problem of early implant induced fibrosis.
  • Further long-term comparative study on wider scale is needed to detect the exact value of this technique and to evaluate its long-term result.
  • [MeSH-major] Glaucoma Drainage Implants. Glaucoma, Open-Angle / surgery. Sclera / transplantation. Sclerostomy / instrumentation
  • [MeSH-minor] Adult. Female. Humans. Intraocular Pressure. Laser Therapy. Male. Middle Aged. Pilot Projects. Prospective Studies. Reoperation / methods. Suture Techniques. Treatment Outcome. Visual Acuity

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  • (PMID = 17024223.001).
  • [ISSN] 0950-222X
  • [Journal-full-title] Eye (London, England)
  • [ISO-abbreviation] Eye (Lond)
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] England
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66. Bahloul M, Chaari A, Khlaf-Bouaziz N, Kallel H, Chaari L, Ben Hamida C, Chelly H, Rekik N, Bouaziz M: [Celiac disease, cerebral venous thrombosis and protein S deficiency, a fortuitous association?]. J Mal Vasc; 2005 Sep;30(4 Pt 1):228-30
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  • [Title] [Celiac disease, cerebral venous thrombosis and protein S deficiency, a fortuitous association?].
  • [Transliterated title] Maladie coeliaque, thrombose veineuse cérébrale et déficit en protéine S, une association fortuite?
  • INTRODUCTION: Celiac disease is a pathology which is rarely associated with thrombosis complications.
  • Cerebral vascular thrombosis has never been described in patients with a celiac disease.
  • OBSERVATION: We report an observation of a 21-year-old girl with a history of celiac disease who was hospitalized in the intensive care unit for convulsive status epilepticus secondary to a cerebral venous thrombosis.
  • The etiologic investigation of this thrombo-embolic complication revealed protein S deficit.
  • Our patient improved under symptomatic treatment.
  • COMMENT: This original observation confirms that celiac disease can be associated with cerebral venous thrombosis.
  • [MeSH-major] Celiac Disease / complications. Cerebral Veins. Protein S Deficiency / complications. Venous Thrombosis / complications
  • [MeSH-minor] Adult. Female. Humans


67. Hampl M, Wentzensen N, Vinokurova S, von Knebel-Doeberitz M, Poremba C, Bender HG, Kueppers V: Comprehensive analysis of 130 multicentric intraepithelial female lower genital tract lesions by HPV typing and p16 expression profile. J Cancer Res Clin Oncol; 2007 Apr;133(4):235-45
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  • [Title] Comprehensive analysis of 130 multicentric intraepithelial female lower genital tract lesions by HPV typing and p16 expression profile.
  • METHODS: One hundred and thirty biopsies of 52 women treated for multicentric synchronous or metachronous lower genital tract intraepithelial neoplasias were collected.
  • HPV16 was frequently found in VIN, VaIN and AIN (73, 60 and 77%, respectively), whereas only 37% of CIN were HPV16 positive.
  • [MeSH-major] Biomarkers, Tumor. Cervical Intraepithelial Neoplasia / virology. Genital Neoplasms, Female / virology. Papillomaviridae / classification. Papillomavirus Infections / virology. Polymerase Chain Reaction / methods
  • [MeSH-minor] Adult. Anus Neoplasms / diagnosis. Anus Neoplasms / genetics. Anus Neoplasms / pathology. Anus Neoplasms / virology. Colposcopy. DNA Primers. DNA, Viral / classification. DNA, Viral / genetics. DNA, Viral / isolation & purification. Female. Gene Expression Regulation, Neoplastic. Gene Expression Regulation, Viral. Genes, p16. Human papillomavirus 16 / genetics. Human papillomavirus 16 / isolation & purification. Humans. Middle Aged. Precancerous Conditions / diagnosis. Precancerous Conditions / genetics. Precancerous Conditions / pathology. Precancerous Conditions / virology. Uterine Cervical Neoplasms / diagnosis. Uterine Cervical Neoplasms / genetics. Uterine Cervical Neoplasms / pathology. Uterine Cervical Neoplasms / virology. Vaginal Neoplasms / diagnosis. Vaginal Neoplasms / genetics. Vaginal Neoplasms / pathology. Vaginal Neoplasms / virology. Vulvar Neoplasms / diagnosis. Vulvar Neoplasms / genetics. Vulvar Neoplasms / pathology. Vulvar Neoplasms / virology

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  • (PMID = 17294241.001).
  • [ISSN] 0171-5216
  • [Journal-full-title] Journal of cancer research and clinical oncology
  • [ISO-abbreviation] J. Cancer Res. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA Primers; 0 / DNA, Viral
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68. Frigui M, Kechaou M, Jemal M, Ben Zina Z, Feki J, Bahloul Z: [Optic neuropathy in Behçet's disease: a series of 18 patients]. Rev Med Interne; 2009 Jun;30(6):486-91
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  • [Transliterated title] Les neuropathies optiques au cours de la maladie de Behçet : à propos de 18 cas.
  • The diagnosis of optic neuropathy was based on the clinical examination, visual field, visual evoked potentials and retinal angiography.

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  • (PMID = 19375828.001).
  • [ISSN] 0248-8663
  • [Journal-full-title] La Revue de medecine interne
  • [ISO-abbreviation] Rev Med Interne
  • [Language] FRE
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Adrenal Cortex Hormones; 0 / Immunosuppressive Agents
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69. Shebl M: Synthesis, spectral and magnetic studies of mono- and bi-nuclear metal complexes of a new bis(tridentate NO2) Schiff base ligand derived from 4,6-diacetylresorcinol and ethanolamine. Spectrochim Acta A Mol Biomol Spectrosc; 2009 Jul 15;73(2):313-23
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  • [Title] Synthesis, spectral and magnetic studies of mono- and bi-nuclear metal complexes of a new bis(tridentate NO2) Schiff base ligand derived from 4,6-diacetylresorcinol and ethanolamine.
  • A new bis(tridentate NO2) Schiff base ligand, H(4)L, was prepared by the reaction of the bifunctional carbonyl compound; 4,6-diacetylresorcinol (DAR) with ethanolamine.
  • The ligand reacted with iron(III), cobalt(II), nickel(II), copper(II), zinc(II), cadmium(II), cerium(III) and uranyl(VI) ions, in absence and in presence of LiOH, to yield mono- and bi-nuclear complexes with different coordinating sites.
  • The ligand and its metal complexes were characterized by elemental analyses, IR, (1)H NMR, electronic, ESR and mass spectra, conductivity and magnetic susceptibility measurements as well as thermal analyses.
  • In absence of LiOH, mononuclear complexes (2, 3 and 5-9) as well as binuclear complexes (1 and 4) were obtained.
  • In mononuclear complexes, the ligand acted as a neutral, mono- and di-basic/bi- and tetra-dentate ligand while in binuclear complexes (1 and 4), the ligand acted as a bis(mono- or di-basic/tridentate) ligand.
  • On the other hand, in presence of LiOH, only binuclear complexes (10-15) were obtained in which the ligand acted as a bis(dibasic tridentate) ligand.
  • The metal complexes exhibited different geometrical arrangements such as octahedral, tetrahedral, square planar, square pyramidal and pentagonal bipyramidal arrangements.
  • [MeSH-major] Ethanolamines / chemistry. Ligands. Magnetics. Metals / chemistry. Nitrogen Dioxide / chemistry. Resorcinols / chemistry. Schiff Bases / chemistry
  • [MeSH-minor] Molecular Structure. Spectrum Analysis / methods

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  • (PMID = 19345138.001).
  • [ISSN] 1386-1425
  • [Journal-full-title] Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
  • [ISO-abbreviation] Spectrochim Acta A Mol Biomol Spectrosc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / 4,6-diacetylresorcinol; 0 / Ethanolamines; 0 / Ligands; 0 / Metals; 0 / Resorcinols; 0 / Schiff Bases; S7G510RUBH / Nitrogen Dioxide
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70. Ibrahim WH, Habib HM, Jarrar AH, Al Baz SA: Effect of Ramadan fasting on markers of oxidative stress and serum biochemical markers of cellular damage in healthy subjects. Ann Nutr Metab; 2008;53(3-4):175-81
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  • [Title] Effect of Ramadan fasting on markers of oxidative stress and serum biochemical markers of cellular damage in healthy subjects.
  • BACKGROUND/AIMS: Ramadan is a holy month for Muslims during which they abstain from eating, drinking and smoking from dawn to sunset.
  • This makes Ramadan a unique model for studying the effects of altered meal patterns in humans.
  • The aim of this study was to determine the effect of Ramadan fasting on markers of oxidative stress and serum biochemical markers of cellular damage in healthy subjects.
  • METHODS: Fourteen healthy volunteers (9 men and 5 women aged 25-58 years) who fasted during Ramadan participated in the study.
  • Blood sampling was conducted 2 days before Ramadan and on days 14 and 28 of Ramadan.
  • The following were measured:.
  • (1) in serum, malondialdehyde (MDA), aspartate aminotransferase, alanine aminotransferase, creatine kinase, alkaline phosphatase, lactate dehydrogenase, blood urea nitrogen, total proteins, uric acid, albumin, glucose, triglycerides and total cholesterol;.
  • (2) in plasma, protein-bound carbonyls, alpha-tocopherol, gamma-tocopherol, retinol, vitamin C and carotenoids, and (3) in erythrocytes, MDA, glutathione, glutathione peroxidase and catalase.
  • RESULTS: Erythrocyte MDA, serum glucose and triglycerides and plasma total carotenoids were significantly lower (p<0.05) on day 28 of Ramadan compared to before Ramadan.
  • The rest of the variables were not significantly altered by Ramadan fasting.
  • CONCLUSION: The results obtained indicate that with the exception of a slight reduction in lipid peroxidative damage in erythrocytes, Ramadan fasting does not alter oxidative stress parameters or biochemical markers of cellular damage in healthy subjects.
  • [MeSH-major] Erythrocytes / chemistry. Fasting / blood. Lipid Peroxidation. Oxidative Stress
  • [MeSH-minor] Adult. Biomarkers / blood. Blood Glucose / metabolism. Carotenoids / blood. Female. Humans. Male. Malondialdehyde / blood. Middle Aged. Triglycerides / blood

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  • [Copyright] Copyright 2008 S. Karger AG, Basel.
  • (PMID = 19011280.001).
  • [ISSN] 1421-9697
  • [Journal-full-title] Annals of nutrition & metabolism
  • [ISO-abbreviation] Ann. Nutr. Metab.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Blood Glucose; 0 / Triglycerides; 36-88-4 / Carotenoids; 4Y8F71G49Q / Malondialdehyde
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71. Abd-El-Maeboud KH, Ghazy AA, Nadeem AA, Al-Sharaky A, Khalil AE: Effect of vaginal pH on the efficacy of vaginal misoprostol for induction of midtrimester abortion. J Obstet Gynaecol Res; 2008 Feb;34(1):78-84
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  • [Title] Effect of vaginal pH on the efficacy of vaginal misoprostol for induction of midtrimester abortion.
  • AIM: To evaluate the effect of vaginal pH on the efficacy of misoprostol for induction of midtrimester abortion.
  • METHODS: The study comprised 110 women, with a gestational age of 14-26 weeks, with a missed abortion as an indication for the induction of abortion.
  • On admission, the vaginal pH was measured and two groups were generated: (A) those with pH<5 (n=63); and (B) those with pH >or= 5 (n=47).
  • All of the women received intravaginal misoprostol tablets moistened with 3 mL of 5% acetic acid, 200 microg every 4 h for a maximum of 5 doses within 24 h.
  • If the patient did not have adequate uterine contractions, the same regimen was repeated over the following 24 h and if no response was achieved, this was considered a failure of therapy.
  • RESULTS: All patients aborted within 48 h.
  • A significant positive correlation between vaginal pH and the misoprostol application-abortion interval was found.
  • The mean induction-abortion interval was significantly shorter in group A compared to group B (12.1 vs 23.6 h, P<0.001), with abortion rates at 24 h being 100% and 63.8%, respectively.
  • Moreover, a significantly lower dose of misoprostol was used in group A with a lower incidence of fever and abdominal pain.
  • CONCLUSION: Vaginal pH influences the efficacy of misoprostol administered vaginally for the induction of midtrimester abortion.
  • The presence of this relationship, despite premoistening misoprostol with an acidifying agent, suggests that the effect of vaginal pH might extend beyond affecting the pharmacokinetics of the drug.
  • [MeSH-major] Abortifacient Agents, Nonsteroidal / administration & dosage. Abortion, Induced. Misoprostol / administration & dosage. Vagina / physiology
  • [MeSH-minor] Administration, Intravaginal. Adolescent. Adult. Female. Humans. Hydrogen-Ion Concentration. Pregnancy. Pregnancy Trimester, Second. Treatment Outcome

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  • (PMID = 18226134.001).
  • [ISSN] 1341-8076
  • [Journal-full-title] The journal of obstetrics and gynaecology research
  • [ISO-abbreviation] J. Obstet. Gynaecol. Res.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Abortifacient Agents, Nonsteroidal; 0E43V0BB57 / Misoprostol
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72. Srikumaran U, Woodard EJ, Leet AI, Rigamonti D, Sponseller PD, Ain MC: Pedicle and spinal canal parameters of the lower thoracic and lumbar vertebrae in the achondroplast population. Spine (Phila Pa 1976); 2007 Oct 15;32(22):2423-31
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  • [Title] Pedicle and spinal canal parameters of the lower thoracic and lumbar vertebrae in the achondroplast population.
  • OBJECTIVE: To characterize pedicle and spinal canal morphology of the achondroplastic lower thoracic and lumbar vertebrae and to suggest dimensions for improving pedicle screw selection and placement.
  • [MeSH-minor] Adolescent. Adult. Anthropometry. Bone Screws / standards. Cohort Studies. Female. Humans. Image Processing, Computer-Assisted. Internal Fixators / standards. Male. Middle Aged. Reconstructive Surgical Procedures / methods. Retrospective Studies. Spinal Canal / pathology. Spinal Fusion / methods. Tomography, X-Ray Computed

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  • (PMID = 18090080.001).
  • [ISSN] 1528-1159
  • [Journal-full-title] Spine
  • [ISO-abbreviation] Spine
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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73. Conlon JM, Al-Ghaferi N, Abraham B, Sonnevend A, King JD, Nielsen PF: Purification and properties of laticeptin, an antimicrobial peptide from skin secretions of the South American frog Leptodactylus laticeps. Protein Pept Lett; 2006;13(4):411-5
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  • [Title] Purification and properties of laticeptin, an antimicrobial peptide from skin secretions of the South American frog Leptodactylus laticeps.

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  • (PMID = 16712520.001).
  • [ISSN] 0929-8665
  • [Journal-full-title] Protein and peptide letters
  • [ISO-abbreviation] Protein Pept. Lett.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antimicrobial Cationic Peptides; 0 / laticeptin, Leptodactylus laticeps
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74. Keshk S, Sameshima K: The utilization of sugar cane molasses with/without the presence of lignosulfonate for the production of bacterial cellulose. Appl Microbiol Biotechnol; 2006 Sep;72(2):291-6
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  • Six strains of Acetobacter xylinum [American Type Culture Collection 10245 and Institute of Fermentation in Osaka (IFO) 13693, 13772, 13773, 14815, and 15237] were screened for their BC production.

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  • (PMID = 16450110.001).
  • [ISSN] 0175-7598
  • [Journal-full-title] Applied microbiology and biotechnology
  • [ISO-abbreviation] Appl. Microbiol. Biotechnol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 8062-15-5 / lignosulfuric acid; 9004-34-6 / Cellulose; 9005-53-2 / Lignin
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75. Malanin K, Telegdy E, Qazaq H: Hair loss and serum zinc values among Arab females in Al Ain region, United Arab Emirates. Eur J Dermatol; 2007 Sep-Oct;17(5):446-7
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  • [Title] Hair loss and serum zinc values among Arab females in Al Ain region, United Arab Emirates.

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  • (PMID = 17673393.001).
  • [ISSN] 1167-1122
  • [Journal-full-title] European journal of dermatology : EJD
  • [ISO-abbreviation] Eur J Dermatol
  • [Language] eng
  • [Publication-type] Comparative Study; Letter
  • [Publication-country] France
  • [Chemical-registry-number] J41CSQ7QDS / Zinc
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76. Xia X, Ling W, Ma J, Xia M, Hou M, Wang Q, Zhu H, Tang Z: An anthocyanin-rich extract from black rice enhances atherosclerotic plaque stabilization in apolipoprotein E-deficient mice. J Nutr; 2006 Aug;136(8):2220-5
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  • ApoE-deficient mice (n = 30; 30 wk old) were randomly divided into 3 groups: a control group (fed the AIN-93G diet), the simvastin group [simva; fed the AIN-93G diet containing simvastatin, 50 mg/(kg.d)], or the anthocyanin-rich extract group [antho; fed the AIN-93G diet supplemented with anthocyanin-rich extract from black rice, 300 mg/(kg.d)].

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  • (PMID = 16857844.001).
  • [ISSN] 0022-3166
  • [Journal-full-title] The Journal of nutrition
  • [ISO-abbreviation] J. Nutr.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anthocyanins; 0 / Anticholesteremic Agents; 0 / Apolipoproteins E; 0 / Plant Extracts; AGG2FN16EV / Simvastatin
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77. Salem SA, Zuel-Fakkar NM, Fathi G, Abd El-Reheem SM, Abd El-monem El-Tabakh A, Ragab DM: Comparative study of human papilloma virus in untreated and ultraviolet-treated psoriatic patients. Photodermatol Photoimmunol Photomed; 2010 Apr;26(2):78-82
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  • [Title] Comparative study of human papilloma virus in untreated and ultraviolet-treated psoriatic patients.
  • BACKGROUND: Psoriasis is a proliferative disease, and human papilloma virus (HPV) may be one of the causative factors underlying its pathogenesis.
  • AIM OF THE STUDY: To study whether the presence of the virus in psoriatic patients is due to the proliferative nature of the disease or due to the immunosuppression induced in patients receiving phototherapy.
  • PATIENTS AND METHODS: Using a nested polymerase chain reaction, a skin biopsy was taken and examined for HPV expression in 20 untreated psoriatic patients, 20 psoriasis patients under phototherapy [narrow band ultraviolet B (UVB)], 20 psoriasis patients under systemic photochemotherapy (psoralen and UVA), 10 healthy controls, and 10 non-psoriatic patients under UV treatment.
  • RESULTS: The virus detection rate in psoriatic patients under photochemotherapy (60%) was significantly higher (P<0.05) compared with the other groups, while the frequency of the virus in the untreated psoriatic group (0%) was statistically insignificant compared with the normal control group (20%).
  • CONCLUSION: UV treatment may be an underlying factor predisposing patients with psoriasis to infectivity by HPV together with other factors.
  • [MeSH-major] PUVA Therapy / adverse effects. Papillomaviridae / metabolism. Papillomavirus Infections / metabolism. Psoriasis / metabolism. Psoriasis / virology
  • [MeSH-minor] Adult. Female. Humans. Male. Middle Aged

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  • (PMID = 20415738.001).
  • [ISSN] 1600-0781
  • [Journal-full-title] Photodermatology, photoimmunology & photomedicine
  • [ISO-abbreviation] Photodermatol Photoimmunol Photomed
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Denmark
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78. el-Fiky LM, Khamis N, Mostafa Bel D, Adly AM: Staphylococcal infection and toxin production in chronic rhinosinusitis. Am J Rhinol Allergy; 2009 May-Jun;23(3):264-7
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  • [Title] Staphylococcal infection and toxin production in chronic rhinosinusitis.
  • BACKGROUND: The association between bacterial colonization and different forms of chronic rhinosinusitis (CRS) has not been well documented.
  • One of the most recent hypotheses is superantigen (SA)-induced inflammation, resulting in up-regulation of lymphocytes to produce cytokines, and other inflammatory mediators that strongly modify the disease.
  • Staphylococcus aureus, frequently encountered in nasal passages, can produce enterotoxins that can act as SAs.
  • METHODS: A prospective case control study was performed.
  • Sixty-four patients diagnosed with CRS (group 1), CRS with nasal polyps (CRSwNP) (group 2), and 15 control subjects were enrolled.
  • Swabs were taken from the middle meatus of all subjects for identification of S. aureus carriers.
  • Positive carriers were analyzed for the presence of toxic shock syndrome toxin (TSST) 1 using reverse passive latex agglutination as well as polymerase chain reaction.
  • RESULTS: The rate of nasal carriage of S. aureus in CRS was 42.8%, that of CRSwNP was 45.4%, and that of the control group was 13.3%.
  • The difference between both groups of CRS and the control group was found to be highly significant (p < 0.001).
  • The detection of TSST-1 was significantly higher (p < 0.001) in both groups of CRS patients than in the control group.
  • Finally, the difference in colonization of TSST-1 was highly significant (p < 0.001) between the CRS group 1 and CRSwNP group 2 patients.
  • CONCLUSION: Identifying SAs and understanding how they elicit the pathogenic condition in CRS will be central in revealing ways to ameliorate their effects and properly treat these conditions.
  • [MeSH-major] Rhinitis / etiology. Sinusitis / etiology. Staphylococcal Infections / complications. Staphylococcus aureus / pathogenicity. Superantigens / biosynthesis
  • [MeSH-minor] Adolescent. Adult. Case-Control Studies. Chronic Disease. Female. Humans. Male. Middle Aged. Prospective Studies

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  • (PMID = 19490799.001).
  • [ISSN] 1945-8924
  • [Journal-full-title] American journal of rhinology & allergy
  • [ISO-abbreviation] Am J Rhinol Allergy
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Superantigens
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79. Anwar WA, Khaled HM, Amra HA, El-Nezami H, Loffredo CA: Changing pattern of hepatocellular carcinoma (HCC) and its risk factors in Egypt: possibilities for prevention. Mutat Res; 2008 Jul-Aug;659(1-2):176-84
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  • [Title] Changing pattern of hepatocellular carcinoma (HCC) and its risk factors in Egypt: possibilities for prevention.
  • The burden of hepatocellular carcinoma (HCC) has been increasing in Egypt with a doubling in the incidence rate in the past 10 years.
  • This has been attributed to several biological (e.g. hepatitis B and C virus infection) and environmental factors (e.g. aflatoxin, AF).
  • Other factors such as cigarette smoking, occupational exposure to chemicals such as pesticides, and endemic infections in the community, such as schistosomiasis, may have additional roles in the etiology or progression of the disease.
  • Estimates of the burden of cancer caused by these factors provide an opportunity for prevention.
  • Previously, there was strong evidence that hepatitis B virus (HBV) was the major cause of HCC in Egypt, but more recently HCV has become the predominant factor associated with the more recent epidemic of HCC.
  • It has been well documented that Egypt has one of the highest prevalence rates of HCV infection in the world.
  • The natural history of HCV infection and disease progression, however, are influenced by additional factors such as duration of infection, age at infection, sex, co-infection with HBV, the level of HCV viraemia and its genotype.
  • The role of exposure to aflatoxins and development of HCC in Egypt was historically less clear.
  • Nevertheless, recent food sampling surveys and population-based studies indicated that exposure to aflatoxins in Egypt may have been underestimated in the past.
  • Recent results indicated that both local and imported samples were positive for aflatoxin B1 (AFB1, 17.5% and 20%, respectively), with concentrations ranging from 3 to 25 microg/kg.
  • The level of AFB1 was dependent on the area of collection as well as the season of the year.
  • In a population-based study, the level and frequency of aflatoxin M1 (AFM1, a major metabolite of aflatoxin B1 excreted in breast milk) was assessed as a biomarker of maternal exposure.
  • The samples were collected from a selected group of 388 Egyptian lactating mothers during May-September 2003.
  • Non-working status, obesity, high corn oil consumption, and the number of offspring contributed to the variability in occurrence of AFM1 in breast milk.
  • Prevention and intervention approaches directed to risk factors of HCC can play a critical role in its prevention.
  • In the case of HCV infection a prevention programme can be achieved by changing personal behaviors and/or cultural habits which are risk factors for HCV transmission, such as injection with contaminated syringes, blood transfusion, surgical operations, venous catheterization, use of common syringes, dental treatment and circumcision at home.
  • Prevention of exposure to aflatoxins can be achieved either at community (via good agriculture practices) or individual levels (treatment or dietary interventions).
  • In conclusion, due to the alarming increase in the incidence of HCC in Egypt, there is a need to further investigate the contribution of these emerging risk factors to the development of HCC in Egypt.
  • This may enable us to determine the susceptibility to HCC among high-risk groups and to provide these individuals with effective measures for early prevention or intervention.
  • [MeSH-major] Carcinoma, Hepatocellular / epidemiology. Liver Neoplasms / epidemiology
  • [MeSH-minor] Aflatoxins / toxicity. Egypt / epidemiology. Hepatitis, Viral, Human / complications. Humans. Pesticides / toxicity. Public Health. Risk Factors


80. Aboughalia AH: Elevation of hyaluronidase-1 and soluble intercellular adhesion molecule-1 helps select bladder cancer patients at risk of invasion. Arch Med Res; 2006 Jan;37(1):109-16
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  • BACKGROUND: The identification of accurate bladder tumor marker/tests could improve diagnosis, recurrence monitoring and treatment in patients with bladder cancer.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Carcinoma, Squamous Cell / metabolism. Carcinoma, Transitional Cell / metabolism. Hyaluronoglucosaminidase / metabolism. Intercellular Adhesion Molecule-1 / metabolism. Urinary Bladder Neoplasms / metabolism

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  • (PMID = 16314195.001).
  • [ISSN] 0188-4409
  • [Journal-full-title] Archives of medical research
  • [ISO-abbreviation] Arch. Med. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 126547-89-5 / Intercellular Adhesion Molecule-1; EC 3.2.1.35 / Hyaluronoglucosaminidase
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81. Hammell M, Long D, Zhang L, Lee A, Carmack CS, Han M, Ding Y, Ambros V: mirWIP: microRNA target prediction based on microRNA-containing ribonucleoprotein-enriched transcripts. Nat Methods; 2008 Sep;5(9):813-9
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  • Recently, a dataset of 3,404 miRNA-associated mRNA transcripts was identified by immunoprecipitation of the RNA-induced silencing complex components AIN-1 and AIN-2.
  • Our analysis of this AIN-IP dataset revealed enrichment for defining characteristics of functional miRNA-target interactions, including structural accessibility of target sequences, total free energy of miRNA-target hybridization and topology of base-pairing to the 5' seed region of the miRNA.
  • We used these enriched characteristics as the basis for a quantitative miRNA target prediction method, miRNA targets by weighting immunoprecipitation-enriched parameters (mirWIP), which optimizes sensitivity to verified miRNA-target interactions and specificity to the AIN-IP dataset.

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  • (PMID = 19160516.001).
  • [ISSN] 1548-7091
  • [Journal-full-title] Nature methods
  • [ISO-abbreviation] Nat. Methods
  • [Language] ENG
  • [Grant] United States / NIGMS NIH HHS / GM / R01 GM047869; United States / NIGMS NIH HHS / GM / R01 GM068726; United States / NIGMS NIH HHS / GM / R01 GM066826; United States / NIGMS NIH HHS / GM / GM34028; United States / NIGMS NIH HHS / GM / GM47869; United States / Howard Hughes Medical Institute / / ; United States / NIGMS NIH HHS / GM / GM034028-25A2; United States / NIGMS NIH HHS / GM / R01 GM034028; United States / NIGMS NIH HHS / GM / R01 GM034028-25A2; United States / NIGMS NIH HHS / GM / GM068726; United States / NIGMS NIH HHS / GM / GM066826
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / AIN-1 protein, C elegans; 0 / Carrier Proteins; 0 / MicroRNAs; 0 / RNA, Messenger; 0 / Ribonucleoproteins
  • [Other-IDs] NLM/ NIHMS290397; NLM/ PMC3092588
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82. Kotb Sultan M, Bakr I, Ahmed Ismail N, Arafa N: Prevalence of unmet contraceptive need among Egyptian women: a community-based study. J Prev Med Hyg; 2010 Jun;51(2):62-6
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  • [Title] Prevalence of unmet contraceptive need among Egyptian women: a community-based study.
  • INTRODUCTION: An estimated 17% of married women in the developing world still have an unmet need for contraception.
  • This study aimed to measure the prevalence and reasons for unmet contraceptive need among married women in the childbearing period in an underprivileged district in Eastern Cairo.
  • METHODS: A cluster survey of 2340 women in the Marg district of Eastern Cairo was performed.
  • Socio-demographic data and data on both past and present contraceptive use were obtained by interview questionnaire.
  • RESULTS: The prevalence of unmet need was 7.4%; 53.4% for limiting and 46.6% for spacing.
  • Experience of side effects from contraceptive use, and fear of side effects, was highly prevalent among women with unmet need.
  • In addition, a large proportion of women with unmet need perceived themselves not to be at risk for conceiving.
  • CONCLUSIONS: A substantial proportion of women in Cairo have unmet contraceptive need.
  • Efficient counseling of women about contraception may help reduce this high prevalence.
  • [MeSH-major] Contraception / statistics & numerical data. Contraception Behavior / statistics & numerical data. Health Knowledge, Attitudes, Practice. Health Services Accessibility / statistics & numerical data. Health Services Needs and Demand / statistics & numerical data. Women's Health
  • [MeSH-minor] Adult. Contraceptive Agents / supply & distribution. Egypt / epidemiology. Female. Health Education / organization & administration. Humans. Prevalence. Urban Population / statistics & numerical data. Women's Health Services / organization & administration. Young Adult

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  • (PMID = 21155407.001).
  • [ISSN] 1121-2233
  • [Journal-full-title] Journal of preventive medicine and hygiene
  • [ISO-abbreviation] J Prev Med Hyg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Contraceptive Agents
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83. Mohamed AA, Mubarak AT, Fawy KF, El-Shahat MF: Modification of AOAC method 973.31 for determination of nitrite in cured meats. J AOAC Int; 2008 Jul-Aug;91(4):820-7
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  • [Title] Modification of AOAC method 973.31 for determination of nitrite in cured meats.
  • A modification of AOAC Method 973.31 is proposed to improve the extraction efficiency of nitrite from cured meat samples and its subsequent quantification based on the diazotization-coupling reaction of sulfanilamide with N-(1-naphthyl)ethylenediamine dihydrochloride (NED).
  • The various experimental parameters were thoroughly investigated.
  • A 5 g meat sample was mixed with 400 mL water; the pH of the mixture was adjusted to 5.5 +/- 0.3 and allowed to stand for 2 h on a water bath at 80 degrees C, with occasional shaking for the complete extraction of nitrite.
  • After quantitative filtration, an aliquot was mixed with chloroacetic-chloroacetate buffer, pH 1.80 +/- 0.05, sulfanilamide, and NED, and the absorbance of the resulting azodye was recorded at 540 nm against water as a reference.
  • Following the recommended procedure, a linear calibration graph was obtained for up to 0.8 microg/mL NO2(-), with a correlation coefficient of 0.9996 and a detection limit (based on the 3 Sb-criterion) of 5.6 ng/mL NO2(-).
  • The proposed method was conveniently applied to various cured meat samples and was validated by comparison with the original AOAC method and by recovery experiments that gave quantitative results (94-98%) with convenient reproducibility.
  • Statistical analysis of the analytical data could not detect any systematic error and revealed the high accuracy and precision of the proposed method.
  • [MeSH-major] Meat / analysis. Nitrites / analysis
  • [MeSH-minor] Buffers. Calibration. Diazonium Compounds / analysis. Food Handling. Hydrogen-Ion Concentration. Indicators and Reagents. Spectrophotometry, Ultraviolet. Sulfanilamides / analysis. Temperature

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  • (PMID = 18727542.001).
  • [ISSN] 1060-3271
  • [Journal-full-title] Journal of AOAC International
  • [ISO-abbreviation] J AOAC Int
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Buffers; 0 / Diazonium Compounds; 0 / Indicators and Reagents; 0 / Nitrites; 0 / Sulfanilamides; 21240MF57M / sulfanilamide
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84. Elsayed H, Traify R, McKeon D, Poullis M: An endobronchial lipoma: diagnosis remains a challenge. J Bronchology Interv Pulmonol; 2010 Jan;17(1):95-6
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  • [Title] An endobronchial lipoma: diagnosis remains a challenge.

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  • (PMID = 23168672.001).
  • [ISSN] 1944-6586
  • [Journal-full-title] Journal of bronchology & interventional pulmonology
  • [ISO-abbreviation] J Bronchology Interv Pulmonol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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85. Al-Saeed TA, Khalil DA: Dispersion compensation in moving-optical-wedge Fourier transform spectrometer. Appl Opt; 2009 Jul 10;48(20):3979-87
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  • [Title] Dispersion compensation in moving-optical-wedge Fourier transform spectrometer.
  • In this paper we study the effect of material dispersion on the performance of a moving-optical-wedge Fourier transform spectrometer.
  • The spectrum is thus evaluated numerically using a test spectrum source.
  • The obtained numerical results show that the classical technique for numerical dispersion compensation, usually used with a Michelson interferometer, cannot be efficiently used with wedge interferometers as it is limited to the cases of weak dispersion.
  • The error in this technique is thus evaluated in different cases and a new numerical technique is proposed to overcome this error.
  • We also notice shrinkage in the interferogram spread in the spatial domain in contradiction with the normal dispersion effect in a Michelson interferometer.
  • [MeSH-major] Algorithms. Artifacts. Spectroscopy, Fourier Transform Infrared / instrumentation
  • [MeSH-minor] Equipment Design. Equipment Failure Analysis. Light. Scattering, Radiation

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  • (PMID = 19593350.001).
  • [ISSN] 1539-4522
  • [Journal-full-title] Applied optics
  • [ISO-abbreviation] Appl Opt
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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86. Kamal SM: Acute hepatitis C: a systematic review. Am J Gastroenterol; 2008 May;103(5):1283-97; quiz 1298
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  • Most patients infected with HCV are unaware of their exposure and remain asymptomatic during the initial stages of the infection, making early diagnosis during the acute phase (first 6 months after infection) unlikely.
  • METHODS: A medical literature search through MEDLINE was conducted using the keyword "acute hepatitis C" with a variety of keywords focused on (a) epidemiology, (b) natural history and outcome, (c) diagnosis, (d) mode of transmission, and (e) treatment.
  • [MeSH-major] Hepatitis C / diagnosis
  • [MeSH-minor] Acute Disease. Antiviral Agents / therapeutic use. Cross-Sectional Studies. Early Diagnosis. Humans. Treatment Outcome

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  • (PMID = 18477352.001).
  • [ISSN] 1572-0241
  • [Journal-full-title] The American journal of gastroenterology
  • [ISO-abbreviation] Am. J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antiviral Agents
  • [Number-of-references] 103
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87. Schkrohowsky JG, Hoernschemeyer DG, Carson BS, Ain MC: Early presentation of spinal stenosis in achondroplasia. J Pediatr Orthop; 2007 Mar;27(2):119-22
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  • [Title] Early presentation of spinal stenosis in achondroplasia.
  • One third of patients with achondroplasia develop spinal stenosis requiring surgical intervention.
  • However, this condition rarely develops before the age of 15 years.
  • The goal of the current study was to identify anatomical factors and clinical symptoms associated with early presentation of lumbar stenosis in such patients.
  • The charts of 22 pediatric patients with achondroplasia who developed lumbar spinal stenosis requiring surgery (subjects) were reviewed retrospectively, focusing on clinical presentation, physical examination findings, and radiographic data.
  • These findings were compared with those of a group of patients who had not developed stenotic symptoms (controls).
  • Analysis was performed using chi2 test.
  • Significance was set at P < 0.05.
  • All 22 subjects presented with neurogenic claudication (weakness, pain, and/or numbness), and 77% had bladder incontinence.
  • Compared radiographically with controls, the subjects had a significantly larger average percentage decrease in the transverse interpedicular distance from T12 to L5 (-8% vs -19%, respectively) and a significantly greater thoracolumbar kyphosis angle (24.2-degree angle vs 14.1-degree angle, respectively).
  • These features were associated with an increased likelihood of developing symptomatic stenosis.
  • The study indicated that 6 patients (32%) of the control group had caudal widening of the lumbar spine from T12 to L5.
  • [MeSH-major] Achondroplasia / complications. Spinal Stenosis / etiology
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Female. Humans. Male. Time Factors

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  • (PMID = 17314632.001).
  • [ISSN] 0271-6798
  • [Journal-full-title] Journal of pediatric orthopedics
  • [ISO-abbreviation] J Pediatr Orthop
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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88. Mazayad SA, Rifaat MM: Megaselia scalaris causing human intestinal myiasis in Egypt. J Egypt Soc Parasitol; 2005 Apr;35(1):331-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Agricultural Workers' Diseases / diagnosis. Diptera / growth & development. Intestinal Diseases, Parasitic / diagnosis. Myiasis / diagnosis

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  • (PMID = 15881016.001).
  • [ISSN] 1110-0583
  • [Journal-full-title] Journal of the Egyptian Society of Parasitology
  • [ISO-abbreviation] J Egypt Soc Parasitol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
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89. Nabhan AF, Rabie NH: Isosorbide mononitrate versus alendronate for postmenopausal osteoporosis. Int J Gynaecol Obstet; 2008 Dec;103(3):213-6
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  • [Title] Isosorbide mononitrate versus alendronate for postmenopausal osteoporosis.
  • OBJECTIVE: To compare the effectiveness, safety, and affordability of isosorbide mononitrate with alendronate for postmenopausal osteoporosis.
  • METHODS: A randomized controlled trial of 60 postmenopausal women with osteoporosis.
  • Participants were randomly assigned to receive either 20 mg daily of isosorbide mononitrate or 70 mg weekly of alendronate for 12 months.
  • Bone mineral density (BMD) was measured using dual X-ray absorptiometry (DXA) at baseline and after 12 months.
  • RESULTS: Both groups showed significant improvement in BMD.
  • Isosorbide mononitrate yielded a comparable effect to alendronate for BMD and T-score at the end of the follow-up period.
  • For BMD and T score the mean differences between the 2 groups were -0.005 (95% CI, -0.02 to 0.03) and 0.31 (95% CI, -0.03 to 0.64), respectively.
  • A 10.8% and 12.1% change in BMD after 12 months was seen for isosorbide mononitrate and alendronate, respectively.
  • CONCLUSION: Isosorbide mononitrate is comparable to alendronate.
  • Nitric oxide donors may be an effective and affordable therapy to improve bone mineral density.
  • [MeSH-major] Alendronate / therapeutic use. Bone Density / drug effects. Bone Density Conservation Agents / pharmacology. Isosorbide Dinitrate / analogs & derivatives. Nitric Oxide Donors / pharmacology. Osteoporosis, Postmenopausal / drug therapy
  • [MeSH-minor] Absorptiometry, Photon. Confidence Intervals. Female. Hospitals, University. Humans. Middle Aged. Treatment Outcome

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  • (PMID = 18805524.001).
  • [ISSN] 0020-7292
  • [Journal-full-title] International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
  • [ISO-abbreviation] Int J Gynaecol Obstet
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Randomized Controlled Trial
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Bone Density Conservation Agents; 0 / Nitric Oxide Donors; IA7306519N / Isosorbide Dinitrate; LX1OH63030 / isosorbide-5-mononitrate; X1J18R4W8P / Alendronate
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90. Rauf MA, Soliman AA, Khattab M: Solvent effect on the spectral properties of Neutral Red. Chem Cent J; 2008;2:19
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  • [Title] Solvent effect on the spectral properties of Neutral Red.
  • BACKGROUND: The study was aimed at investigating the effect of various solvents on the absorption spectra of Neutral Red, a dye belonging to the quinone-imine class of dyes.
  • The solvents chosen for the study were water, ethanol, acetonitrile, acetone, propan-1-ol, chloroform, nitrobenzene, ethyleneglycol, acetic acid, DMSO and DMF.
  • RESULTS: The results have shown that the absorption maxima of dyes are dependent on solvent polarity.
  • In non-hydrogen-bond donating solvents, solvation of dye molecules probably occurs via dipole-dipole interactions, whereas in hydrogen-bond donating solvents the phenomenon is more hydrogen bonding in nature.
  • To estimate the contribution of the different variables on the wave number of the Neutral Red dye, regression analyses using the ECW model were compared with the pi* scale model.
  • This showed that the unified scale for estimating the solvent effect on the absorption of the Neutral Red dye is more adopted and more applicable than the pi* scale model.
  • CONCLUSION: Absorption maxima of dyes are dependent on solvent polarity.
  • Solvation of dye molecules probably occurs via dipole-dipole interactions in non-hydrogen-bond donating solvents, whereas in hydrogen-bond donating solvents the phenomenon is more hydrogen bonding in nature.
  • The unified scale for estimating the solvent effect on the absorption of Neutral Red dye is more adopted and more applicable than the pi* scale model.
  • This may be due to complications from both pi-pi* charge transfer interactions and incomplete complexation of the solute; these effects are averaged out in the derived beta and pi parameters and thus limit their applicability.

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  • [Cites] Spectrochim Acta A Mol Biomol Spectrosc. 2004 Sep;60(11):2433-9 [15294225.001]
  • [Cites] Spectrochim Acta A Mol Biomol Spectrosc. 2002 Nov;58(13):2971-82 [12477042.001]
  • (PMID = 18799016.001).
  • [ISSN] 1752-153X
  • [Journal-full-title] Chemistry Central journal
  • [ISO-abbreviation] Chem Cent J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2571090
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91. Al-Salam S, Algawi K, Alashari M: Malignant non-teratoid medulloepithelioma of ciliary body with retinoblastic differentiation: a case report and review of literature. Neuropathology; 2008 Oct;28(5):551-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A preliminary diagnosis of retinoblastoma with extraocular extension was made.
  • All tumor cells showed no immunoreactivity to cytokeratin 7, cytokeratin 20, epithelial membrane antigen, carcinoembryonic antigen, desmin, GFAP, and chromogranin.
  • [MeSH-minor] Biomarkers, Tumor / analysis. Cell Differentiation. Child. Diagnosis, Differential. Glaucoma / etiology. Humans. Immunohistochemistry. Male. Retinoblastoma / pathology

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  • (PMID = 18410270.001).
  • [ISSN] 1440-1789
  • [Journal-full-title] Neuropathology : official journal of the Japanese Society of Neuropathology
  • [ISO-abbreviation] Neuropathology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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92. Ellouze S, Khabir A, Ayadi L, Makni S, Amouri A, Frikha M, Sellami-Boudawara T: [Unusual tumor of the stomach]. Gastroenterol Clin Biol; 2008 Mar;32(3):289-91
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  • [Transliterated title] Tumeur inhabituelle de l'estomac.
  • Histopathologic examination confirmed the diagnosis of a gastric infiltration by a melanoma.
  • The diagnosis of polymetastasis from a melanoma without primitive was kept.

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  • (PMID = 18343616.001).
  • [ISSN] 0399-8320
  • [Journal-full-title] Gastroentérologie clinique et biologique
  • [ISO-abbreviation] Gastroenterol. Clin. Biol.
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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93. Esmat A, El-Demerdash E, El-Mesallamy H, Abdel-Naim AB: Toxicity and oxidative stress of acrylonitrile in rat primary glial cells: preventive effects of N-acetylcysteine. Toxicol Lett; 2007 Jul 10;171(3):111-8
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  • [Title] Toxicity and oxidative stress of acrylonitrile in rat primary glial cells: preventive effects of N-acetylcysteine.

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  • (PMID = 17606339.001).
  • [ISSN] 0378-4274
  • [Journal-full-title] Toxicology letters
  • [ISO-abbreviation] Toxicol. Lett.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Cyanides; 0 / Free Radical Scavengers; 0 / Glial Fibrillary Acidic Protein; 8L70Q75FXE / Adenosine Triphosphate; EC 1.1.1.27 / L-Lactate Dehydrogenase; GAN16C9B8O / Glutathione; MP1U0D42PE / Acrylonitrile; WYQ7N0BPYC / Acetylcysteine
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94. Petroianu GA, Arafat K, Kuca K, Kassa J: Five oximes (K-27, K-33, K-48, BI-6 and methoxime) in comparison with pralidoxime: in vitro reactivation of red blood cell acetylcholinesterase inhibited by paraoxon. J Appl Toxicol; 2006 Jan-Feb;26(1):64-71
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  • [Title] Five oximes (K-27, K-33, K-48, BI-6 and methoxime) in comparison with pralidoxime: in vitro reactivation of red blood cell acetylcholinesterase inhibited by paraoxon.
  • Oximes are cholinesterase reactivators of use in poisoning with organophosphorus compounds.
  • Pralidoxime (PRX) is used clinically as an adjunct to atropine in such exposure.
  • Clinical experience with PRX (and other oximes) is, however, disappointing and routine use has been questioned.
  • In addition it is known that oximes are not equally effective against all existing organophosphorus compounds.
  • There is a clear demand for 'broad spectrum' cholinesterase reactivators with a higher efficacy than PRX.
  • Over the years new reactivators of cholinesterase of potential clinical utility have been developed.
  • Their chemical structures were derived from those of existing esterase reactivators, especially pralidoxime, obidoxime and HI-6.
  • The purpose of the study was to quantify in vitro the extent of oxime (pralidoxime, K-27, K-33, K-48, methoxime and BI-6) conferred protection, using paraoxon as an inhibitor.
  • Paraoxon (POX), the active metabolite of parathion (O,O-diethyl-O-p-nitro-phenyl phosphorothioate) is a non-neuropathic organophosphate.
  • Red blood cell (RBC) acetylcholinesterase (AChE) activities in whole blood were measured photometrically in the presence of different POX concentrations and the IC50 was calculated.
  • Determinations were repeated in the presence of increasing oxime concentrations.
  • The IC50 of POX increases with the oxime concentration in a linear manner.
  • The calculated IC50 values were plotted against the oxime concentrations to obtain an IC50 shift curve.
  • The slope of the shift curve (tg alpha) was used to quantify the magnitude of the protective effect (nm IC50 increase per microm reactivator).
  • Based on our determinations the new K series of reactivators is far superior to pralidoxime, methoxime and BI-6, K-27 being the outstanding compound with a tg alpha value of 3.7 (nm IC50 increase per microm reactivator) which is approximately 13 times the reactivator ability of PRX.
  • In general there is an (expected) inverse relationship between the binding constant K and the slope of the IC50 shift curve (tg alpha) for all oximes examined.
  • K-27 (the most protective substance judging by the tg alpha) has the lowest K value (highest affinity).
  • In vivo testing of the new oximes as an organophosphate protective agent is necessary.
  • [MeSH-major] Acetylcholinesterase / metabolism. Cholinesterase Reactivators / pharmacology. Erythrocytes / drug effects. Oximes / pharmacology
  • [MeSH-minor] Cholinesterase Inhibitors / toxicity. Female. Humans. In Vitro Techniques. Inhibitory Concentration 50. Male. Paraoxon / toxicity

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  • [Copyright] 2005 John Wiley & Sons, Ltd.
  • (PMID = 16193529.001).
  • [ISSN] 0260-437X
  • [Journal-full-title] Journal of applied toxicology : JAT
  • [ISO-abbreviation] J Appl Toxicol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Cholinesterase Inhibitors; 0 / Cholinesterase Reactivators; 0 / Oximes; EC 3.1.1.7 / Acetylcholinesterase; Q9CX8P80JW / Paraoxon
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95. Karam SM, John R, Alpers DH, Ponery AS: Retinoic acid stimulates the dynamics of mouse gastric epithelial progenitors. Stem Cells; 2005 Mar;23(3):433-41
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  • [Title] Retinoic acid stimulates the dynamics of mouse gastric epithelial progenitors.
  • The gastric epithelial progenitors proliferate and undergo bipolar migration associated with their differentiation into pit, parietal, and zymogenic cell lineages.
  • In conclusion, 3-day treatment of retinoic acid enhances the proliferation of gastric epithelial progenitors and the dynamics of their progeny.
  • [MeSH-major] Epithelial Cells / cytology. Gastric Mucosa / cytology. Stem Cells / drug effects. Tretinoin / pharmacology

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  • (PMID = 15749938.001).
  • [ISSN] 1066-5099
  • [Journal-full-title] Stem cells (Dayton, Ohio)
  • [ISO-abbreviation] Stem Cells
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 5688UTC01R / Tretinoin; G34N38R2N1 / Bromodeoxyuridine
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96. Pirog EC, Quint KD, Yantiss RK: P16/CDKN2A and Ki-67 enhance the detection of anal intraepithelial neoplasia and condyloma and correlate with human papillomavirus detection by polymerase chain reaction. Am J Surg Pathol; 2010 Oct;34(10):1449-55
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  • [Title] P16/CDKN2A and Ki-67 enhance the detection of anal intraepithelial neoplasia and condyloma and correlate with human papillomavirus detection by polymerase chain reaction.
  • The classification of anal intraepithelial neoplasia (AIN) in mucosal biopsies is subject to considerable interobserver variability.
  • Previous studies have shown that Ki-67 and p16/CDKN2A immunostains aid detection of dysplasia in biopsy samples from the uterine cervix.
  • The aim of this study was to determine whether Ki-67 and p16/CDKN2A immunolabeling enhanced diagnostic accuracy in the assessment of anal mucosal biopsies from patients with suspected human papillomavirus (HPV) infection.
  • The study consisted of 75 cases that were originally interpreted to represent normal anal transitional zone (n=15), fibroepithelial polyp (n=10), condyloma accuminatum (n=10), low-grade AIN (AIN1, n=20), and high-grade AIN (n=20), including 10 cases each of AIN2 and AIN3.
  • Thus, the final study group consisted of 17 samples of normal anal transition zone, 14 fibroepithelial polyps, 6 condylomata accuminata, and 38 cases of AIN (11 AIN1, 16 AIN2, and 11 AIN3).
  • A positive Ki-67 result was defined as the presence of a cluster of at least 2 strongly stained epithelial nuclei in the upper two-thirds of the epithelial thickness.
  • None of the anal transition zone samples or fibroepithelial polyps showed Ki-67 or p16/CDKN2A staining.
  • All condylomata and samples of AIN contained HPV DNA and showed positive Ki-67 labeling.
  • All cases of high-grade AIN showed positive p16/CDKN2A staining.
  • We conclude that Ki-67 labeling detects anal HPV-related changes with a high degree of sensitivity and specificity, whereas increased p16/CDKN2A staining is strongly associated with high-grade squamous neoplasia.
  • These results indicate that a combination of these markers may aid interpretation of anal mucosal biopsy samples.
  • [MeSH-major] Anus Neoplasms / diagnosis. Carcinoma in Situ / diagnosis. Condylomata Acuminata / diagnosis. Cyclin-Dependent Kinase Inhibitor p16 / metabolism. Ki-67 Antigen / metabolism. Papillomaviridae / isolation & purification. Papillomavirus Infections / diagnosis
  • [MeSH-minor] Adult. Aged. Biomarkers, Tumor / metabolism. Biopsy. Colonic Polyps / metabolism. Colonic Polyps / pathology. Colonic Polyps / virology. DNA Probes, HPV. Female. Humans. Immunohistochemistry. Male. Middle Aged. Precancerous Conditions / diagnosis. Precancerous Conditions / metabolism. Precancerous Conditions / virology. Predictive Value of Tests. Young Adult

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  • (PMID = 20871219.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / DNA Probes, HPV; 0 / Ki-67 Antigen
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97. Abdou NE, Mahfouz ME: Ultrastructural and genetic diversity studies of two Sclerocollum (Acanthocephala) species infecting Siganid and Lutianid fishes from the Red Sea, Egypt. J Egypt Soc Parasitol; 2006 Dec;36(3):1035-56
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  • [Title] Ultrastructural and genetic diversity studies of two Sclerocollum (Acanthocephala) species infecting Siganid and Lutianid fishes from the Red Sea, Egypt.
  • Little is known about the distribution of Acanthocephala in local waters.
  • A survey was carried out on the commercially important herbivorous Siganid fish, Siganus rivulatus and S. luridus, as well as Lutianid fish Centropristisfilamentosus inhabiting the Red Sea to determine the prevalence of Acanthocephala parasites.
  • One hundred and thirteen fish were examined.
  • The infection rates of S. rivulatus and S. luridus with Sclerocollum rubrimaris Schmidt and Paperna 1978 (Rhadinorhynchidae: Gorgorhynchinae) were 59 % & 33%, respectively.
  • Meanwhile, 59% of C. filamentosus were found infected by Sclerocollum sp.
  • The abundance, host-parasite relationships and microhabitat of S. rubrimaris were investigated and discussed.
  • SEM was the employed to investigate the differences between the two species of Sclerocollum.
  • For accurate estimation of genetic diversity of these species, randomly amplified polymorphic DNA (RAPD) genomic fingerprinting was proposed, using four different random primers.
  • SEM studies showed that the two examined species differ in the length of proboscis hooks, the number of longitudinal rows of hooks on proboscis, distance between the bases of hooks and in egg size.
  • The trunk surface of Sclerocollum sp. had minute, scale-like spines that were arranged in oblique lines whereas the trunk surface of S. rubrimaris had small pores and sclerotised plates on its anterior portion.
  • RAPD primers revealed 52 amplification products and species-specific markers were identified.
  • The deduced phenogram comprised two main clusters each includes one of the examined Sclerocollum species.
  • Results indicated that RAPD markers are useful for the assessment of genetic diversity between the investigated Sclerocollum species which concur with SEM outcome.
  • [MeSH-major] Acanthocephala / genetics. Acanthocephala / ultrastructure. DNA, Helminth / analysis. Fish Diseases / parasitology. Genetic Variation. Helminthiasis, Animal / parasitology
  • [MeSH-minor] Animals. Fishes. Host-Parasite Interactions. Indian Ocean. Random Amplified Polymorphic DNA Technique / veterinary. Species Specificity

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  • (PMID = 17153712.001).
  • [ISSN] 1110-0583
  • [Journal-full-title] Journal of the Egyptian Society of Parasitology
  • [ISO-abbreviation] J Egypt Soc Parasitol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
  • [Chemical-registry-number] 0 / DNA, Helminth
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98. Corr P: Imaging of neuro-AIDS. J Psychosom Res; 2006 Sep;61(3):295-9
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  • Imaging findings are often nonspecific; however, correlations with patient's clinical signs and CD4 count allow a working diagnosis to be made.
  • [MeSH-major] Acquired Immunodeficiency Syndrome / diagnosis. Brain / pathology. Brain / radiography. HIV Infections / diagnosis. Magnetic Resonance Imaging. Tomography, X-Ray Computed
  • [MeSH-minor] Antigens, CD4 / immunology. Humans. Meningitis, Cryptococcal / diagnosis. Meningitis, Cryptococcal / microbiology. Opportunistic Infections / diagnosis. Toxoplasmosis, Cerebral / diagnosis. Toxoplasmosis, Cerebral / microbiology

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  • (PMID = 16938504.001).
  • [ISSN] 0022-3999
  • [Journal-full-title] Journal of psychosomatic research
  • [ISO-abbreviation] J Psychosom Res
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD4
  • [Number-of-references] 17
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99. El-Hodhod MA, Tomoum HY, Abd Al-Aziz MM, Samaan SM: Serum Fas and Bcl-2 in patients with epilepsy. Acta Neurol Scand; 2006 May;113(5):315-21
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  • In addition to laboratory and radiological investigations needed for diagnosis and follow-up, soluble Fas (s.Fas) and Bcl-2 were assayed in sera of patients and controls by enzyme-linked immunosorbent assay technique.

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  • (PMID = 16629767.001).
  • [ISSN] 0001-6314
  • [Journal-full-title] Acta neurologica Scandinavica
  • [ISO-abbreviation] Acta Neurol. Scand.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Anticonvulsants; 0 / Antigens, CD95; 0 / Biomarkers; 0 / Proto-Oncogene Proteins c-bcl-2
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100. Emara AA, Abou-Hussen AA: Spectroscopic studies of bimetallic complexes derived from tridentate or tetradentate Schiff bases of some di- and tri-valent transition metals. Spectrochim Acta A Mol Biomol Spectrosc; 2006 Jul;64(4):1010-24
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  • [Title] Spectroscopic studies of bimetallic complexes derived from tridentate or tetradentate Schiff bases of some di- and tri-valent transition metals.
  • Two series of new binuclear complexes with Schiff base ligands, H(4)L(a) or H(2)L(b), derived from the reaction of 4,6-diacetylresorcinol and ethylenediamine, in the molar ratio 1:1 and 1:2 have been prepared, respectively.
  • The two ligands react with Co(II), Ni(II), Cu(II), Zn(II), Cd(II), Cr(III) and Fe(III)-nitrates to get binuclear complexes.
  • The ligands were characterized by elemental analysis, IR, UV-vis, (1)H NMR and mass spectra.
  • The complexes were synthesized by direct and template methods.
  • Different types of products were obtained for the same ligand and metal salts according to the method of preparation.
  • The H(4)L(a) ligand behaves as a macrocyclic tetrabasic with two N(2)O(2) sits, while the H(2)L(b) ligand behaves as a dibasic with two N(2)O sites.
  • The H(4)L(a) ligand is a compartmental ligand which hosts the two metal ions at the centers of two cis-N(2)O(2) sites, while the metal complexes of H(2)L(b) ligand are binuclear, where the ligand hosts two metal ions at the centers of two N(2)O sites.
  • In both cases, deprotonation of the hydrogen atoms of the phenolic OH groups occur except in the case of the Ni(II), Fe(III) and Cr(III) complexes.
  • Electronic spectra and magnetic moments of the complexes indicate that the geometries of the metal centers are either octahedral or tetrahedral.
  • The structures are consistent with the IR, UV-vis, ESR, (1)H NMR, mass spectra, and thermal gravimetric analysis (TGA/DTA) as well as conductivity and magnetic moment measurements.
  • [MeSH-major] Metals / chemistry. Organometallic Compounds / chemistry. Schiff Bases / chemistry. Spectrophotometry / methods. Transition Elements / chemistry
  • [MeSH-minor] Electrons. Hot Temperature. Ligands. Models, Chemical

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  • (PMID = 16332449.001).
  • [ISSN] 1386-1425
  • [Journal-full-title] Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
  • [ISO-abbreviation] Spectrochim Acta A Mol Biomol Spectrosc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Ligands; 0 / Metals; 0 / Organometallic Compounds; 0 / Schiff Bases; 0 / Transition Elements
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