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51. Devaiah AK, Andreoli MT: Treatment of esthesioneuroblastoma: a 16-year meta-analysis of 361 patients. Laryngoscope; 2009 Jul;119(7):1412-6
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  • [Title] Treatment of esthesioneuroblastoma: a 16-year meta-analysis of 361 patients.
  • OBJECTIVES/HYPOTHESIS: This study reviews the published outcomes related to surgical (open, endoscopic, and endoscopic-assisted) and nonsurgical treatment for esthesioneuroblastoma.
  • METHODS: A meta-analysis of individual patient data for esthesioneuroblastoma publications between 1992 (the earliest identified description of endoscopic resection) and 2008 was conducted.
  • A total of 49 journal articles, comprising 1,170 cases of esthesioneuroblastoma, were included in the study.
  • [MeSH-major] Endoscopy. Esthesioneuroblastoma, Olfactory / surgery. Nasal Cavity. Nose Neoplasms / surgery
  • [MeSH-minor] Humans. Neoplasm Staging. Statistics, Nonparametric. Survival Analysis


52. Wang SL, Li SH, Chen WT, Chai CY: Absence of Epstein-Barr virus in olfactory neuroblastoma. Pathology; 2007 Dec;39(6):565-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Absence of Epstein-Barr virus in olfactory neuroblastoma.
  • AIMS: The sinonasal region is a frequent site for Epstein-Barr virus (EBV) related tumours, including nasopharyngeal carcinoma, sinonasal undifferentiated carcinoma and malignant lymphoma.
  • Olfactory neuroblastoma is a rare neoplasm, arises from olfactory epithelium, is found in the upper nasal cavity, and may be confused morphologically with the above tumours.
  • Our aim was to determine whether EBV is associated with olfactory neuroblastoma.
  • METHODS: We collected tissue samples for 16 olfactory neuroblastomas over an 11-year period at Kaohsiung Medical University Hospital.
  • RESULTS: None of the epithelial cells in the 16 cases of olfactory neuroblastoma was positive for EBV.
  • CONCLUSIONS: EBV does not play a major role in the aetiology of olfactory neuroblastoma.
  • [MeSH-major] Epstein-Barr Virus Infections / pathology. Esthesioneuroblastoma, Olfactory / secondary. Herpesvirus 4, Human / isolation & purification. Nasal Cavity / pathology. Nose Neoplasms / pathology

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  • (PMID = 18027259.001).
  • [ISSN] 0031-3025
  • [Journal-full-title] Pathology
  • [ISO-abbreviation] Pathology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / RNA, Viral
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53. Myssiorek D, Tronco G: 111Indium pentetreotide imaging in the evaluation of head and neck tumors. Laryngoscope; 2005 Oct;115(10):1707-16
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVES/HYPOTHESIS: Peptide receptor imaging with Indium pentetreotide is useful in the diagnosis of diffuse neuroendocrine system tumors (DNEST) of the head and neck.
  • CONCLUSIONS: Indium pentetreotide scintigraphy is accurate in determining the presence of paragangliomas, carcinoid tumors, esthesioneuroblastomas, small cell neuroendocrine tumors, andmetastases.

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  • (PMID = 16222183.001).
  • [ISSN] 0023-852X
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Indium Radioisotopes; 0 / Radiopharmaceuticals; 0 / Receptors, Somatostatin; 51110-01-1 / Somatostatin; G083B71P98 / pentetreotide
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4. Sołtys J, Pietniczka-Załeska M, Młyńczyk-Budzynowska K, Majkowski J: [Neoplasms of paranasal sinuses in material of ENT Department MSS Hospital in Warsaw between 2006-2007]. Otolaryngol Pol; 2008;62(4):451-4
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  • [Title] [Neoplasms of paranasal sinuses in material of ENT Department MSS Hospital in Warsaw between 2006-2007].
  • Tumors of paranasal sinuses present a small percent of tumors detected in the region of head and neck 3-4% and they present a fraction of a percent of tumors in general /0.16%/.
  • MATERIAL: In the years 2004 and 2005, the National Register of Neoplasms recorded 120 and 132 cases of malignant tumors of paranasal sinuses, respectively.
  • Between 2006-2007 we treated 15 patients with tumors of paranasal sinuses underwent treatment at the ENT department of the MiEdzyleski Szpital Specjalistyczny in Warsaw.
  • THE RESULTS: We detected the following:--benign neoplasms: 2 cases of angiofibroma, 3 cases of inverted papilloma;--malignant tumors: 4 cases of Ca planoepitheliale, 1 instance of adenocarcinoma, 1 instance of Ca anaplasticum, 1--melanoma, 1--esthesioneuroblastoma, 1--lymphoma malignum, 1--metastatic tumor.
  • THE CONCLUSIONS: at the moment of the admission for treatment at the ENT department, the advancement stage of tumor T3/T4, from the first signs until the proper diagnosis was that marked with the passage of eight months.
  • Ca planoepitheliale is the most common type of malignant tumors of paranasal sinuses.
  • It is only good cooperation between the surgeon and the pathologist which makes it possible to put the proper diagnosis.
  • [MeSH-major] Carcinoma / diagnosis. Nose Neoplasms / diagnosis. Paranasal Sinus Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Female. Hospitals, Public. Humans. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging. Otorhinolaryngologic Surgical Procedures / methods. Poland. Retrospective Studies. Treatment Outcome

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  • (PMID = 18837222.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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55. Shukla RC, Singh PK, Senthil S, Pathak R: Esthesioneuroblastoma: a case report. Nepal Med Coll J; 2010 Jun;12(2):128-32
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  • [Title] Esthesioneuroblastoma: a case report.
  • Esthesioneuroblastoma (olfactory neuroblastoma) is an uncommon neuroectodermal tumor.
  • Patients often present with nasal obstruction, rhinorrhea, recurrent epistaxis, hyposmia, or anosmia.
  • We report a case of esthesioneuroblastoma involving bilateral nasal cavity leading to bilateral nasal obstruction, epistaxis and proptosis of the right eye associated with decreased visual acquity on that eye and loss of smell.
  • A diffuse nontender, 6x6 cms swelling with illdefined margins was seen over the nasal bridge, extending superiorly to glabella and laterally to right maxillary region.
  • X-ray PNS showed soft tissue mass in the nasal cavity with destruction of nasal septum, intense periosteal reaction with destruction of right maxillary wall and extension to right orbit.
  • CT scan of paranasal sinuses showed 8.5 x 4.9 x 7.8 cms irregularly marginated heterogeneous iso- to hyper dense soft tissue mass lesion with extensive adjacent bony destruction and spiculated periosteal reaction involving bilateral nasal cavity and anterior cranial fossa.
  • Biopsy from right nasal mass showed neuroblastoma.
  • The modified Kadish staging system, lymph node status, treatment modality, and age are useful predictors of survival in patients who present with esthesioneuroblastoma.
  • Excellent outcomes for esthesioneuroblastoma are achievable.
  • Long-term follow-up is necessary because of the extended interval for recurrent disease; unlike most sinonasal malignancies, surgical salvage is possible.
  • [MeSH-major] Esthesioneuroblastoma, Olfactory. Nasal Cavity. Nose Neoplasms
  • [MeSH-minor] Adult. Combined Modality Therapy. Humans. Male. Nasal Obstruction / etiology. Tomography, X-Ray Computed

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  • (PMID = 21222414.001).
  • [Journal-full-title] Nepal Medical College journal : NMCJ
  • [ISO-abbreviation] Nepal Med Coll J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Nepal
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56. Benfari G, Fusconi M, Ciofalo A, Gallo A, Altissimi G, Celani T, De Vincentiis M: Radiotherapy alone for local tumour control in esthesioneuroblastoma. Acta Otorhinolaryngol Ital; 2008 Dec;28(6):292-7
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  • [Title] Radiotherapy alone for local tumour control in esthesioneuroblastoma.
  • Esthesioneuroblastoma is an uncommon tumour.
  • Due to its low incidence, this neoplasm is difficult to evaluate and its treatment remains a matter of debate.
  • With reference to the treatment of esthesioneuroblastoma, 55 patients submitted only to radiotherapy have been selected from publications of internationally indexed literature between 1979 and 2006.
  • There was no evidence of disease in: 6/6 stage A patients with a median follow-up period of 103.6 months, 7/12 stage B patients with a median followup period of 120 months, and 7/37 stage C patients with a median follow-up period of 77.3 months.
  • A total of 27 patients died due to tumour-related causes and 5 due to intercurrent disease, while 3 patients were alive with disease (local recurrence and cervical lymph node metastasis).
  • In conclusion, esthesioneuroblastoma is a malignant tumour which grows both locoregionally and distantly.
  • [MeSH-major] Esthesioneuroblastoma, Olfactory / radiotherapy. Nasal Cavity. Nose Neoplasms / radiotherapy
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Disease-Free Survival. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Staging. Radiotherapy Dosage. Retrospective Studies. Time Factors. Treatment Failure. Treatment Outcome

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  • (PMID = 19205593.001).
  • [ISSN] 0392-100X
  • [Journal-full-title] Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale
  • [ISO-abbreviation] Acta Otorhinolaryngol Ital
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 20
  • [Other-IDs] NLM/ PMC2689543
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57. Ozsahin M, Gruber G, Olszyk O, Karakoyun-Celik O, Pehlivan B, Azria D, Roelandts M, Kaanders JH, Cengiz M, Krengli M, Matzinger O, Zouhair A: Outcome and prognostic factors in olfactory neuroblastoma: a rare cancer network study. Int J Radiat Oncol Biol Phys; 2010 Nov 15;78(4):992-7
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  • [Title] Outcome and prognostic factors in olfactory neuroblastoma: a rare cancer network study.
  • PURPOSE: To assess the outcome in patients with olfactory neuroblastoma (ONB).
  • METHODS AND MATERIALS: Seventy-seven patients treated for nonmetastatic ONB between 1971 and 2004 were included.
  • Sixty-eight patients presented with N0 (88%) disease.
  • The 5-year overall survival (OS), disease-free survival (DFS), locoregional control, and local control were 64%, 57%, 62%, and 70%, respectively.
  • In univariate analyses, favorable factors were Kadish A or B disease, T1-T3 tumors, no nodal involvement, curative surgery, R0/R1 resection, and RT-dose 54 Gy or higher.
  • CONCLUSION: In this multicenter retrospective study, patients with ONB treated with R0 or R1 surgical resection followed by at least 54-Gy postoperative RT had the best outcome.
  • Novel strategies including concomitant chemotherapy and/or higher dose RT should be prospectively investigated in this rare disease for which local failure remains a problem.
  • [MeSH-major] Esthesioneuroblastoma, Olfactory / therapy. Nose Neoplasms / therapy
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Analysis of Variance. Combined Modality Therapy / methods. Disease-Free Survival. Female. Humans. Male. Middle Aged. Nasal Cavity / pathology. Neoplasm Staging. Radiotherapy Dosage. Retrospective Studies. Treatment Outcome. Young Adult

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  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20231062.001).
  • [ISSN] 1879-355X
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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58. Chen YF, Yang AK, Zhang Q, Ouyang D, Chen WK, Chen FJ: [Clinical analysis of 53 cases of esthesioneuroblastoma]. Ai Zheng; 2009 Mar;28(3):308-11
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  • [Title] [Clinical analysis of 53 cases of esthesioneuroblastoma].
  • BACKGROUND AND OBJECTIVE: The prognosis of esthesioneuroblastoma (ENB) patients is poor.
  • CONCLUSIONS: ENB is a malignant tumor with high rates of locoregional recurrence and distant metastasis.
  • [MeSH-major] Esthesioneuroblastoma, Olfactory / surgery. Nasal Cavity. Nose Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Child. Combined Modality Therapy. Female. Humans. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Recurrence, Local. Neoplasm Staging. Radiotherapy, High-Energy. Retrospective Studies. Survival Rate. Young Adult

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  • (PMID = 19619448.001).
  • [Journal-full-title] Ai zheng = Aizheng = Chinese journal of cancer
  • [ISO-abbreviation] Ai Zheng
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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59. Liao H, Hua QQ, Wu ZY: [Maxillary swing approach in the management of tumors in the central and lateral cranial base]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2006 Apr;41(4):276-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Among them, five suffered from chordoma, two had rhabdomyosarcoma, two had squamous cell carcinoma, one had malignant fibrous histiocytoma, one had malignant melanoma, one had esthesioneuroblastoma, one had invaded hypophysoma, two had schwannoma, one had pleomorphic adenoma, and one had angiofibroma.
  • Of the 12 malignant tumors, the 1-and 2-year survival rate were 91.67% and 72.92%, respectively.

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  • (PMID = 16848177.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] China
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60. Sharma S, Lasheen W, Walsh D: Paraneoplastic refractory hypercalcemia due to advanced metastatic esthesioneuroblastoma. Rhinology; 2008 Jun;46(2):153-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Paraneoplastic refractory hypercalcemia due to advanced metastatic esthesioneuroblastoma.
  • Esthesioneuroblastoma (ENB) is a rare malignant neoplasm arising from the olfactory neuroepithelium.
  • ENB has no distinctive clinical picture, but often presents as chronic unilateral nasal obstruction or epistaxis.
  • [MeSH-major] Esthesioneuroblastoma, Olfactory / secondary. Hypercalcemia / etiology. Nasal Cavity. Nose Neoplasms / pathology. Paraneoplastic Syndromes / etiology


61. Lund V, Howard DJ, Wei WI: Endoscopic resection of malignant tumors of the nose and sinuses. Am J Rhinol; 2007 Jan-Feb;21(1):89-94
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic resection of malignant tumors of the nose and sinuses.
  • However, the rarity and long natural history of malignant tumors make it difficult to accrue cohorts comparable with the established gold standard of craniofacial resection.
  • METHODS: In this prospective cohort study, after histological confirmation and a staging imaging protocol, patients deemed suitable were offered the option of an entirely endoscopic resection as an alternative to craniofacial resection.
  • A wide range of pathologies included 15 cases of adenocarcinoma, 11 malignant melanomas, and 11 olfactory neuroblastomas.
  • Thirty-six patients are alive and well, 7 patients have residual disease, 4 patients are dead of disease, and 2 patients have died of intercurrent disease.
  • [MeSH-major] Endoscopy / methods. Nose Neoplasms / surgery. Paranasal Sinus Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Disease-Free Survival. Female. Follow-Up Studies. Humans. Length of Stay. Magnetic Resonance Imaging. Male. Middle Aged. Prospective Studies. Survival Rate. Time Factors. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 17283568.001).
  • [ISSN] 1050-6586
  • [Journal-full-title] American journal of rhinology
  • [ISO-abbreviation] Am J Rhinol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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62. Madani I, Bonte K, Vakaet L, Boterberg T, De Neve W: Intensity-modulated radiotherapy for sinonasal tumors: Ghent University Hospital update. Int J Radiat Oncol Biol Phys; 2009 Feb 1;73(2):424-32
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  • The tumor histologic type was adenocarcinoma in 54, squamous cell carcinoma in 17, esthesioneuroblastoma in 9, and adenoid cystic carcinoma in 4.
  • The tumors were located in the ethmoid sinus in 47, maxillary sinus in 19, nasal cavity in 16, and multiple sites in 2.
  • The 5-year local control, overall survival, disease-specific survival, disease-free survival, and freedom from distant metastasis rate was 70.7%, 58.5%, 67%, 59.3%, and 82.2%, respectively.
  • [MeSH-major] Nose Neoplasms / radiotherapy. Paranasal Sinus Neoplasms / radiotherapy. Radiotherapy, Intensity-Modulated
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Disease-Free Survival. Female. Follow-Up Studies. Hospitals, University. Humans. Male. Middle Aged. Multivariate Analysis. Neoplasm Recurrence, Local / mortality. Neoplasm Recurrence, Local / radiotherapy. Radiotherapy Dosage. Survival Rate. Treatment Outcome

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  • (PMID = 18755554.001).
  • [ISSN] 1879-355X
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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63. Gore MR, Zanation AM: Salvage treatment of late neck metastasis in esthesioneuroblastoma: a meta-analysis. Arch Otolaryngol Head Neck Surg; 2009 Oct;135(10):1030-4
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  • [Title] Salvage treatment of late neck metastasis in esthesioneuroblastoma: a meta-analysis.
  • OBJECTIVE: Esthesioneuroblastoma (ENB) is an uncommon tumor of the sinonasal region with a 20% rate of neck metastases.
  • To our knowledge, the rate of neck metastases occurring 6 or more months after diagnosis has not been well characterized.
  • The rate of successful salvage of these late neck metastases, defined in this study as disease-free survival for at least 1 year, has not been previously reported.
  • PATIENTS: A total of 678 patients with ENB with 79 patients with neck metastases occurring 6 or more months after the initial diagnosis.
  • MAIN OUTCOME MEASURES: The rate of successful salvage of late neck metastases, defined as disease-free survival for at least 1 year, was compared for the 3 treatment groups.
  • An odds ratio (OR) analysis revealed that surgery plus radiation provided a statistically significant increase in the rate of successful salvage in patients with late neck metastases, with an OR of 8.6 vs single modality therapy and a number-needed-to-treat of 3.
  • CONCLUSION: Treatment of neck metastases occurring 6 or more months after an initial diagnosis of ENB with combined surgery and radiotherapy provides a statistically significant survival advantage vs single-modality therapy.
  • [MeSH-major] Esthesioneuroblastoma, Olfactory / pathology. Head and Neck Neoplasms / secondary. Head and Neck Neoplasms / therapy. Nasal Cavity / pathology. Nose Neoplasms / pathology. Salvage Therapy / methods

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  • (PMID = 19841344.001).
  • [ISSN] 1538-361X
  • [Journal-full-title] Archives of otolaryngology--head & neck surgery
  • [ISO-abbreviation] Arch. Otolaryngol. Head Neck Surg.
  • [Language] eng
  • [Publication-type] Journal Article; Meta-Analysis
  • [Publication-country] United States
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64. Diaz EM Jr, Johnigan RH 3rd, Pero C, El-Naggar AK, Roberts DB, Barker JL, DeMonte F: Olfactory neuroblastoma: the 22-year experience at one comprehensive cancer center. Head Neck; 2005 Feb;27(2):138-49
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Olfactory neuroblastoma: the 22-year experience at one comprehensive cancer center.
  • BACKGROUND: Olfactory neuroblastoma (ONB) is a rare tumor arising from the olfactory neuroepithelium.
  • METHODS: Thirty patients treated for ONB at The University of Texas M. D.
  • The diagnosis of ONB was histologically confirmed for each patient.
  • Nine patients whose disease was initially stage C had a recurrence.
  • Anderson Cancer Center approach to ONB is complete surgical resection, usually involving a craniofacial approach, with postoperative radiation therapy.
  • This approach seems to be curative in early-stage disease.
  • [MeSH-major] Esthesioneuroblastoma, Olfactory / diagnosis. Esthesioneuroblastoma, Olfactory / therapy. Nasal Cavity. Nose Neoplasms / diagnosis. Nose Neoplasms / therapy
  • [MeSH-minor] Academic Medical Centers. Adolescent. Adult. Aged. Combined Modality Therapy. Disease-Free Survival. Female. Humans. Male. Middle Aged. Neoplasm Staging. Retrospective Studies. Survival Rate. Texas. Treatment Outcome

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  • [Copyright] 2004 Wiley Periodicals, Inc.
  • (PMID = 15654688.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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65. Lin JH, Tsai DH, Chiang YH: A primary sellar esthesioneuroblastomas with unusual presentations: a case report and reviews of literatures. Pituitary; 2009;12(1):70-5
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  • [Title] A primary sellar esthesioneuroblastomas with unusual presentations: a case report and reviews of literatures.
  • The development of an esthesioneuroblastoma outside to the region in which olfactory epithelium exists is extremely rare.
  • The author presents a 40 years-old man with ectopic esthesioneuroblastoma in sella turcica.
  • Moreover, differential diagnosis and the origin of the ectopic esthsioneuroblastoma would be discussed.
  • [MeSH-major] Esthesioneuroblastoma, Olfactory / pathology. Sella Turcica / pathology

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  • [Cites] Cancer. 2004 Nov 15;101(10):2257-60 [15484215.001]
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  • (PMID = 18176843.001).
  • [ISSN] 1573-7403
  • [Journal-full-title] Pituitary
  • [ISO-abbreviation] Pituitary
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 23
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66. Sharma NK, Pandey J, Gupta N, Jain RK: Growth and physiological response of Arthrobacter protophormiae RKJ100 toward higher concentrations of o-nitrobenzoate and p-hydroxybenzoate. FEMS Microbiol Lett; 2007 Jun;271(1):65-70
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  • In the present study we have characterized the growth response and physiological changes (adaptations) of a Gram-positive bacterium, Arthrobacter protophormiae RKJ100, toward the higher concentrations of two aromatic compounds, viz. o-nitrobenzoate (ONB) and p-hydroxybenzoate (PHB).
  • Arthrobacter protophormiae RKJ100 could utilize 30 mM ONB and 50 mM PHB as sole sources of carbon and energy.
  • It was capable of growth on higher concentrations of ONB (up to 200 mM) and PHB (up to 150 mM) when the cells were pre-exposed to lower concentrations of these compounds.
  • In addition, Bacterial Adhesion To Hydrocarbon (BATH) assay and scanning electron microscopy showed substantial increase in cell surface hydrophobicity and decrease in cell size of A. protophormiae RKJ100 when grown on ONB and PHB as compared to succinate-grown cells.

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  • (PMID = 17391368.001).
  • [ISSN] 0378-1097
  • [Journal-full-title] FEMS microbiology letters
  • [ISO-abbreviation] FEMS Microbiol. Lett.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / 2-nitrobenzoate; 0 / Fatty Acids; 0 / Nitrobenzoates; 0 / Parabens; 7440-44-0 / Carbon; AB6MNQ6J6L / Succinic Acid; JG8Z55Y12H / 4-hydroxybenzoic acid
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67. Daly ME, Chen AM, Bucci MK, El-Sayed I, Xia P, Kaplan MJ, Eisele DW: Intensity-modulated radiation therapy for malignancies of the nasal cavity and paranasal sinuses. Int J Radiat Oncol Biol Phys; 2007 Jan 1;67(1):151-7
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  • [Title] Intensity-modulated radiation therapy for malignancies of the nasal cavity and paranasal sinuses.
  • PURPOSE: To report the clinical outcome of patients treated with intensity-modulated radiation therapy (IMRT) for malignancies of the nasal cavity and paranasal sinuses.
  • The primary sites were: 13 ethmoid sinus, 10 maxillary sinus, 7 nasal cavity, and 6 other.
  • Histology was: 12 squamous cell, 7 esthesioneuroblastoma, 5 adenoid cystic, 5 undifferentiated, 5 adenocarcinoma, and 2 other.
  • The 5-year rates of disease-free and overall survival were 55% and 45%, respectively.
  • CONCLUSION: Although IMRT for malignancies of the sinonasal region does not appear to lead to significant improvements in disease control, the low incidence of complications is encouraging.
  • [MeSH-major] Nose Neoplasms / radiotherapy. Paranasal Sinus Neoplasms / radiotherapy. Radiotherapy, Intensity-Modulated
  • [MeSH-minor] Adenocarcinoma / radiotherapy. Adenocarcinoma / secondary. Adult. Aged. Aged, 80 and over. Carcinoma, Adenoid Cystic / radiotherapy. Carcinoma, Adenoid Cystic / secondary. Carcinoma, Squamous Cell / radiotherapy. Carcinoma, Squamous Cell / secondary. Esthesioneuroblastoma, Olfactory / radiotherapy. Esthesioneuroblastoma, Olfactory / secondary. Female. Humans. Male. Middle Aged. Nasal Cavity. Neoplasm Staging. Radiation Injuries / etiology. Radiotherapy Dosage

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  • (PMID = 17189068.001).
  • [ISSN] 0360-3016
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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68. Kryzanski JT, Annino DJ, Gopal H, Heilman CB: Low complication rates of cranial and craniofacial approaches to midline anterior skull base lesions. Skull Base; 2008 Jul;18(4):229-41
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  • The remainder had frontoethmoidal cancer, mucoceles/invasive nasal polyps, encephalocele, esthesioneuroblastoma, anterior falx dermoid cyst with a nasal sinus tract, or invasive pituitary adenoma.
  • When possible, the dura was repaired before entering the nasal cavity.

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  • (PMID = 19119338.001).
  • [ISSN] 1531-5010
  • [Journal-full-title] Skull base : official journal of North American Skull Base Society ... [et al.]
  • [ISO-abbreviation] Skull Base
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2467480
  • [Keywords] NOTNLM ; Anterior skull base / cerebrospinal fluid leak / complications / craniofacial approach / meningioma / skull base surgery
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69. Wang SY, Zhu L, Li SM, Lin L, Zheng SX, Wu YF, Zhu XZ: [Sinonasal teratocarcinosarcoma: a clinical, radiologic and pathologic study of 5 cases]. Zhonghua Bing Li Xue Za Zhi; 2007 Aug;36(8):534-8
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  • OBJECTIVE: To study the clinical, radiologic and pathologic features, as well as differential diagnosis of teratocarcinosarcoma in nasal cavity and paranasal sinuses.
  • The clinical presentation was nasal obstruction, epistaxis and headache.
  • Computed tomography showed a homogeneous nasal mass with obturation of sinuses.
  • The initial biopsy diagnosis included capillary hemangioma, olfactory neuroblastoma, craniopharyngioma and malignant mixed tumor.
  • CONCLUSIONS: Sinonasal teratocarcinosarcoma is a rare and highly malignant tumor occurring in sinonasal tract.
  • "Fetal-type" clear cells, squamous epithelium and immature neuroepithelium represent important histologic characteristics useful in diagnosis.
  • [MeSH-major] Carcinosarcoma / pathology. Nasal Cavity. Nose Neoplasms / pathology. Paranasal Sinus Neoplasms / pathology. Teratocarcinoma / pathology
  • [MeSH-minor] Adult. Follow-Up Studies. Humans. Keratins / metabolism. Lymphatic Metastasis. Male. Mucin-1 / metabolism. Neck Dissection. Neoplasm Recurrence, Local

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  • (PMID = 17980101.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Mucin-1; 68238-35-7 / Keratins
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70. Zafereo ME, Fakhri S, Prayson R, Batra PS, Lee J, Lanza DC, Citardi MJ: Esthesioneuroblastoma: 25-year experience at a single institution. Otolaryngol Head Neck Surg; 2008 Apr;138(4):452-8
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  • [Title] Esthesioneuroblastoma: 25-year experience at a single institution.
  • OBJECTIVES: To evaluate outcomes for patients with esthesioneuroblastoma treated at a single institution during a 25-year period.
  • DESIGN: Eighteen patients with pathologic diagnosis of esthesioneuroblastoma between 1980 and 2004 were retrospectively identified.
  • RESULTS: Two patients had Kadish A, seven had Kadish B, and nine had Kadish C disease.
  • The 10-year disease-specific survival was 80%.
  • CONCLUSION: Both endoscopic and open surgical approaches have been successful in treating a small number of esthesioneuroblastoma patients with high survival and low rate of surgical complications.
  • [MeSH-major] Esthesioneuroblastoma, Olfactory / surgery. Nasal Cavity. Nose Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Disease-Free Survival. Female. Humans. Male. Middle Aged. Neck Dissection. Radiation Dosage. Retrospective Studies

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  • (PMID = 18359353.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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71. Schwartz TH, Fraser JF, Brown S, Tabaee A, Kacker A, Anand VK: Endoscopic cranial base surgery: classification of operative approaches. Neurosurgery; 2008 May;62(5):991-1002; discussion 1002-5
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  • METHODS: We prospectively compiled a comprehensive database of our endonasal endoscopic operations, detailing the nasal sinus transgressed, the cranial base approach, and the intracranial target for the first 150 consecutive cases performed at our institution.
  • RESULTS: We categorized the endonasal endoscopic cranial base operations into four nasal corridors, nine cranial base approaches, and 13 intracranial targets.
  • Pathology encountered included pituitary tumor (50%), meningocele/encephalocele (14%), craniopharyngioma and Rathke cleft cyst (10%), meningioma (8%), chordoma (5%), esthesioneuroblastoma (2%), and other (11%).
  • A clear understanding of the possible approaches is facilitated by an awareness of the nasal corridors and intracranial targets.
  • [MeSH-minor] Female. Humans. Male. Nasal Cavity / surgery

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  • (PMID = 18580797.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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72. Kalala L, Focan C, Schils F, Gilles R, Abraham F, Reginster P, Van Den Berge D: [Esthesioneuroblastoma: a case report and literature review]. Rev Med Liege; 2009 Mar;64(3):119-23
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  • [Title] [Esthesioneuroblastoma: a case report and literature review].
  • [Transliterated title] Esthésioneuroblastome: à propos d'un cas et revue de la littérature.
  • Esthesioneuroblastoma (ENB) or olfactive neuroblastoma is a rare cancer arising from the neuroepithelium of the olfactory epithelium of the nasal cavity.
  • The anatomopathological diagnosis will frequently require immuno-histochemical tests and sometimes electron-microscopy as well as genetic testing.
  • [MeSH-major] Esthesioneuroblastoma, Olfactory. Nasal Cavity. Nose Neoplasms

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  • (PMID = 19418930.001).
  • [ISSN] 0370-629X
  • [Journal-full-title] Revue médicale de Liège
  • [ISO-abbreviation] Rev Med Liege
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Belgium
  • [Number-of-references] 18
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73. Casiraghi O, Lefèvre M: [Undifferentiated malignant round cell tumors of the sinonasal tract and nasopharynx]. Ann Pathol; 2009 Sep;29(4):296-312
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  • [Title] [Undifferentiated malignant round cell tumors of the sinonasal tract and nasopharynx].
  • [Transliterated title] Tumeurs malignes indifférenciées à cellules rondes des cavités naso-sinusiennes et du nasopharynx.
  • Undifferentiated malignant round cell tumors of the sinonasal tract and nasopharynx comprise of aggressive malignant neoplasms with overlapping morphologic features, which yet are very different and can be identified as carcinoma, lymphoma, sarcoma, melanoma or olfactory neuroblastoma.
  • The use of a panel of immunohistochemical markers and the identification, in some cases, of specific chromosomal translocations are most often required.
  • We describe clinical, morphological, immunohistochemical and molecular features as well as therapeutic management and prognosis of rhabdomyosarcoma (RMS), Ewing sarcoma/primitive neuroectodermic tumor (EWS/PNET), nonkeratinizing nasopharyngeal carcinoma, undifferentiated subtype (UCNT), olfactory neuroblastoma (ONB), small cell carcinoma, neuroendocrine type (SCCNET), sinonasal undifferentiated carcinoma (SNUC) and mucosal melanoma.
  • The most important features of diagnosis will be summarized in two tables.
  • [MeSH-major] Nasopharyngeal Neoplasms / pathology. Paranasal Sinus Neoplasms / pathology
  • [MeSH-minor] Carcinoma / pathology. Esthesioneuroblastoma, Olfactory / pathology. Humans. Melanoma / pathology. Nasal Cavity. Neuroectodermal Tumors, Primitive / pathology. Nose Neoplasms / pathology. Rhabdomyosarcoma / pathology. Sarcoma, Ewing / pathology

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  • (PMID = 19900635.001).
  • [ISSN] 0242-6498
  • [Journal-full-title] Annales de pathologie
  • [ISO-abbreviation] Ann Pathol
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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74. Han A, Kristjansson AK, Gilliam AC, Jacobs G, Eisenberg R: Pigmented olfactory neuroblastoma: a CD56-positive mimic of melanoma. Arch Dermatol; 2008 Feb;144(2):270-2
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  • [Title] Pigmented olfactory neuroblastoma: a CD56-positive mimic of melanoma.
  • [MeSH-major] Antigens, CD56 / analysis. Esthesioneuroblastoma, Olfactory / diagnosis. Esthesioneuroblastoma, Olfactory / immunology. Melanoma / diagnosis. Nasal Cavity. Nose Neoplasms / immunology
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Humans. Male

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  • (PMID = 18283196.001).
  • [ISSN] 1538-3652
  • [Journal-full-title] Archives of dermatology
  • [ISO-abbreviation] Arch Dermatol
  • [Language] eng
  • [Grant] United States / NIAMS NIH HHS / AR / P30-AR 39750; United States / NIAMS NIH HHS / AR / R01 AR 049284
  • [Publication-type] Case Reports; Letter; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD56
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75. Sahai-Srivastava S, Subhani D: Adverse effect profile of lidocaine injections for occipital nerve block in occipital neuralgia. J Headache Pain; 2010 Dec;11(6):519-23
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  • To determine whether there are differences in the adverse effect profile between 1, 2 and 5% Lidocaine when used for occipital nerve blocks (ONB) in patients with occipital neuralgia.
  • Retrospective chart analysis of all ONB was performed at our headache clinic during a 6-year period on occipital neuralgia patients.
  • 89 consecutive patients with occipital neuralgia underwent a total of 315 ONB.
  • ONB is a safe procedure with 1% Lidocaine; however, caution should be exerted with 5% in elderly patients, 70 or older, especially when administering bilateral injections.

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  • (PMID = 20665065.001).
  • [ISSN] 1129-2377
  • [Journal-full-title] The journal of headache and pain
  • [ISO-abbreviation] J Headache Pain
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 98PI200987 / Lidocaine
  • [Other-IDs] NLM/ PMC3476234
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76. Folbe A, Herzallah I, Duvvuri U, Bublik M, Sargi Z, Snyderman CH, Carrau R, Casiano R, Kassam AB, Morcos JJ: Endoscopic endonasal resection of esthesioneuroblastoma: a multicenter study. Am J Rhinol Allergy; 2009 Jan-Feb;23(1):91-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic endonasal resection of esthesioneuroblastoma: a multicenter study.
  • BACKGROUND: This study reports the combined experience of the University of Miami and University of Pittsburgh with endoscopic endonasal resection of esthesioneuroblastoma (ENB).
  • The two other cases had one patient that required an additional craniotomy approach to complete the resection of a positive lateral dual margin, another patient had positive margins at the orbital apex.
  • Mean follow-up period for the primarily treated cases was 45.2 months (11-152 months), all were disease free at the most recent available follow-up.
  • [MeSH-major] Endoscopy / methods. Esthesioneuroblastoma, Olfactory / surgery. Nasal Cavity. Nose Neoplasms / surgery. Otorhinolaryngologic Surgical Procedures / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Staging. Retrospective Studies. Treatment Outcome. Young Adult

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  • [ErratumIn] Am J Rhinol Allergy. 2009 Mar-Apr;23(2):238. Kassam, Amin Bardai [added]; Morcos, Jacques J [added]
  • (PMID = 19379620.001).
  • [ISSN] 1945-8924
  • [Journal-full-title] American journal of rhinology & allergy
  • [ISO-abbreviation] Am J Rhinol Allergy
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study
  • [Publication-country] United States
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77. Castelnuovo P, Bignami M, Delù G, Battaglia P, Bignardi M, Dallan I: Endonasal endoscopic resection and radiotherapy in olfactory neuroblastoma: our experience. Head Neck; 2007 Sep;29(9):845-50
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  • [Title] Endonasal endoscopic resection and radiotherapy in olfactory neuroblastoma: our experience.
  • BACKGROUND: Our aim was to evaluate the efficacy of a bimodal method of treatment consisting in endoscopic resection followed by radiotherapy in patients with olfactory neuroblastoma (ON).
  • CONCLUSIONS: This method of treatment causes minimal injury to the patients, reduces side effects, and improves the quality of life of those with olfactory neuroblastoma.
  • [MeSH-major] Endoscopy / methods. Esthesioneuroblastoma, Olfactory / radiotherapy. Esthesioneuroblastoma, Olfactory / surgery. Nose Neoplasms / radiotherapy. Nose Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Nasal Cavity. Quality of Life. Radiotherapy, Adjuvant. Retrospective Studies

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  • [Copyright] (c) 2007 Wiley Periodicals, Inc. Head Neck, 2007.
  • (PMID = 17427966.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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78. Vergani F, Pirola E, Fiori L, Pagni F, Parmigiani F, Sganzerla EP: Combined transcranial and endoscopic nasal resection for esthesioneuroblastoma. Technical note. J Neurosurg Sci; 2007 Jun;51(2):99-102
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  • [Title] Combined transcranial and endoscopic nasal resection for esthesioneuroblastoma. Technical note.
  • Esthesioneuroblastoma is a rare malignant neoplasm arising in the nasal cavity.
  • Huge esthesioneuroblastomas, extending into the ethmoid roof and the cribriform plate, or invading the anterior cranial fossa, have traditionally been treated by craniofacial resection.
  • Because of the invasiveness and potentially disfiguring results of a transfacial approach, a new technique has been proposed, combining endoscopic nasal and anterior craniotomy resection.
  • We describe the case of a young male presenting with a large esthesioneuroblastoma involving the nasal cavity and the anterior cranial fossa, causing a huge skull base destruction.
  • A combined transcranial and endoscopic nasal resection resulted in a macroscopically total removal of the tumor.
  • [MeSH-major] Cranial Fossa, Anterior / surgery. Endoscopy / methods. Esthesioneuroblastoma, Olfactory / surgery. Nasal Cavity / surgery. Neurosurgical Procedures / methods. Nose Neoplasms / surgery
  • [MeSH-minor] Adult. Blood Coagulation Disorders. Cranial Sinuses / pathology. Craniotomy / methods. Ethmoid Bone / pathology. Ethmoid Bone / surgery. Humans. Magnetic Resonance Imaging. Male. Nasal Septum / surgery. Nasal Septum / transplantation. Olfactory Mucosa / pathology. Postoperative Hemorrhage / drug therapy. Postoperative Hemorrhage / prevention & control. Reconstructive Surgical Procedures / methods. Surgical Flaps. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 17571044.001).
  • [ISSN] 0390-5616
  • [Journal-full-title] Journal of neurosurgical sciences
  • [ISO-abbreviation] J Neurosurg Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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79. Almubaslat M, Africk C: Cerebral vasospasm after resection of an esthesioneuroblastoma: case report and literature review. Surg Neurol; 2007 Sep;68(3):322-8; discussion 328
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  • [Title] Cerebral vasospasm after resection of an esthesioneuroblastoma: case report and literature review.
  • We illustrate in this report a case of cerebral vasospasm after resection of an esthesioneuroblastoma in an adult patient.
  • This is the first report of vasospasm after resection of this neoplasm.
  • Radiological studies revealed a large frontal lobe mass extending through the cribriform plate into the ethmoid sinus with accompanying brain edema.
  • The patient underwent a craniotomy for resection of the neoplasm.
  • Pathological findings were consistent with a high-grade esthesioneuroblastoma.
  • [MeSH-major] Esthesioneuroblastoma, Olfactory / surgery. Nasal Cavity. Nose Neoplasms / surgery. Postoperative Complications. Vasospasm, Intracranial / etiology

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  • (PMID = 17586013.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 35
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80. Papoutsi Z, Kassi E, Halabalaki M, Mitakou S, Moutsatsou P: Evaluation of estrogenic/antiestrogenic activity of Onobrychis ebenoides extract - interaction with estrogen receptor subtypes ERalpha and ERbeta. Toxicol In Vitro; 2007 Apr;21(3):364-70
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  • To investigate the molecular mechanisms that underly the beneficial effect of O. ebenoides (Onb) on bone loss, we studied its potential to activate ER subtypes (ERalpha and ERbeta) on transiently transfected HeLa cells with HO-hERalpha or pSG5-hERbeta and 3xERE-TATA-Luc expression vectors.
  • (1) Onb extract displayed a significant estrogenic activity on both ERalpha and ERbeta subtypes. (2) It exhibited direct action on osteoblasts by inducing mineralization. (3) It showed estrogenic activity in MCF7 cells.
  • These findings suggest that the beneficial effect of Onb extract on bone loss is mediated through an estrogen-like action via activation of ERalpha-ERE and ERbeta-ERE pathways and via direct action on the mineralization process of osteoblasts.

  • Hazardous Substances Data Bank. FULVESTRANT .
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  • (PMID = 17092687.001).
  • [ISSN] 0887-2333
  • [Journal-full-title] Toxicology in vitro : an international journal published in association with BIBRA
  • [ISO-abbreviation] Toxicol In Vitro
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Estrogen Antagonists; 0 / Estrogen Receptor alpha; 0 / Estrogen Receptor beta; 0 / IGFBP3 protein, human; 0 / Insulin-Like Growth Factor Binding Protein 3; 0 / Insulin-Like Growth Factor Binding Proteins; 0 / Phytoestrogens; 0 / Plant Extracts; 22X328QOC4 / fulvestrant; 4TI98Z838E / Estradiol; EC 1.13.12.- / Luciferases
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81. Lettau M, Laible M: [Diffuse subdural recurrence of an esthesioneuroblastoma]. Rofo; 2010 Oct;182(10):907-8
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  • [Title] [Diffuse subdural recurrence of an esthesioneuroblastoma].
  • [MeSH-major] Esthesioneuroblastoma, Olfactory / diagnosis. Magnetic Resonance Imaging. Neoplasm Recurrence, Local / diagnosis. Positron-Emission Tomography. Subdural Space. Tomography, X-Ray Computed
  • [MeSH-minor] Adolescent. Biopsy. Combined Modality Therapy. Cranial Fossa, Anterior / pathology. Ethmoid Sinus / pathology. Fluorodeoxyglucose F18. Humans. Lymphatic Metastasis / pathology. Male. Maxillary Sinus / pathology. Necrosis. Neoplasm Invasiveness. Orbit / pathology

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  • (PMID = 20563963.001).
  • [ISSN] 1438-9010
  • [Journal-full-title] RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
  • [ISO-abbreviation] Rofo
  • [Language] ger
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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82. Unal A, Ozlugedik S, Tezer MS, Kulacoglu S, Ozcan M: An atypical esthesioneuroblastoma of the inferior nasal cavity and maxillary sinus: report of a case. Tumori; 2006 Sep-Oct;92(5):440-3
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  • [Title] An atypical esthesioneuroblastoma of the inferior nasal cavity and maxillary sinus: report of a case.
  • Esthesioneuroblastoma is a rare malignant tumor of the nasal cavity that originates from the olfactory epithelium.
  • The tumor originated from the maxillary sinus and alveolar process, and was independent of the olfactory region.
  • The patient was a 14-year-old girl presenting with facial swelling and nasal obstruction.
  • Paranasal computed tomography showed a mass filling the right nasal cavity, infiltrating the alveolar process, eroding the anterior wall of the maxilla and invading the subcutaneous tissues of the cheek.
  • Fine-needle aspiration and incisional biopsies identified an esthesioneuroblastoma.
  • [MeSH-major] Esthesioneuroblastoma, Olfactory. Maxillary Sinus Neoplasms. Nasal Cavity. Nose Neoplasms

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  • (PMID = 17168440.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 30
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83. Bachar G, Goldstein DP, Shah M, Tandon A, Ringash J, Pond G, Gullane PJ, Perez-Ordonez B, Gilbert RW, Brown DH, Gentili F, O'Sullivan B, Irish JC: Esthesioneuroblastoma: The Princess Margaret Hospital experience. Head Neck; 2008 Dec;30(12):1607-14
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  • [Title] Esthesioneuroblastoma: The Princess Margaret Hospital experience.
  • BACKGROUND: Esthesioneuroblastoma is rare.
  • Local disease control was 82.6% at 5 years.
  • Recurrence was seen in 33% with local and regional disease recurrence at 15% and 18%, respectively.
  • [MeSH-major] Esthesioneuroblastoma, Olfactory / therapy. Nasal Cavity. Neoplasm Recurrence, Local / therapy. Nose Neoplasms / therapy
  • [MeSH-minor] Adult. Aged. Female. Follow-Up Studies. Hospitals, University. Humans. Male. Middle Aged. Neck Dissection. Neoplasm Staging. Ontario. Retrospective Studies. Survival Analysis. Treatment Outcome

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  • [Copyright] (c) 2008 Wiley Periodicals, Inc.
  • (PMID = 18798301.001).
  • [ISSN] 1097-0347
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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84. Nichols AC, Chan AW, Curry WT, Barker FG, Deschler DG, Lin DT: Esthesioneuroblastoma: the massachusetts eye and ear infirmary and massachusetts general hospital experience with craniofacial resection, proton beam radiation, and chemotherapy. Skull Base; 2008 Sep;18(5):327-37
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  • [Title] Esthesioneuroblastoma: the massachusetts eye and ear infirmary and massachusetts general hospital experience with craniofacial resection, proton beam radiation, and chemotherapy.
  • OBJECTIVES: To determine the efficacy of craniofacial resection and proton radiation for the management of esthesioneuroblastoma (ENB).
  • MAIN OUTCOME MEASURES: Disease-free and overall survival.
  • Nasal obstruction was the most common presenting symptom.
  • Three patients presented with Kadish stage B disease and seven with stage C.
  • No patient had evidence of cervical or metastatic disease at presentation.
  • The 5-year disease-free and overall survival rates were 90% and 85.7%, respectively, by Kaplan-Meier analysis.

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  • [Cites] Arch Otolaryngol Head Neck Surg. 2003 Nov;129(11):1186-92 [14623748.001]
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  • (PMID = 19240832.001).
  • [ISSN] 1531-5010
  • [Journal-full-title] Skull base : official journal of North American Skull Base Society ... [et al.]
  • [ISO-abbreviation] Skull Base
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2637063
  • [Keywords] NOTNLM ; Esthesioneuroblastoma / craniofacial resection / proton radiation
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85. Kiprian D: [Strategy of combined treatment in patient with cancer of paranasal sinuses]. Otolaryngol Pol; 2007;61(4):527-30
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  • [Title] [Strategy of combined treatment in patient with cancer of paranasal sinuses].
  • In 2003, in Poland there were 132 new patients diagnosed for this disease.
  • There is a very rare neoplasm as a olfactory neuroblastoma in this localization.
  • Cancer of the paranasal sinuses infiltrates only locoregionally.
  • The treatment of cancers of paranasal sinuses is always surgery with adjuvant irradiation.
  • [MeSH-major] Paranasal Sinus Neoplasms / diagnosis. Paranasal Sinus Neoplasms / therapy
  • [MeSH-minor] Combined Modality Therapy. Humans. Incidence. Neoplasm Staging. Radiotherapy, Conformal. Treatment Outcome

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  • (PMID = 18260245.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Poland
  • [Number-of-references] 5
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86. Mandhani A, Dharaskar A, Kapoor R: Technical steps of open radical cystectomy and orthotopic neobladder to achieve the goals of "minimally invasive surgery"? Indian J Urol; 2010 Jul;26(3):457-60
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  • Technical modifications in open approach to radical cystectomy and orthotopic neobladder (ONB), that is, Pfannenstiel incision, single urethral catheter, internal splint, and extraperitonealization of the ONB were done in 36 patients.

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  • (PMID = 21116377.001).
  • [ISSN] 1998-3824
  • [Journal-full-title] Indian journal of urology : IJU : journal of the Urological Society of India
  • [ISO-abbreviation] Indian J Urol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2978457
  • [Keywords] NOTNLM ; Open radical cystectomy / laparoscopic radical cystectomy / minimally invasive surgery / robotic radical cystectomy
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87. Martin DA, Hogg JP: Illustrated approach to imaging and staging of nodal disease in the neck. Curr Probl Diagn Radiol; 2010 Mar-Apr;39(2):62-73
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  • [Title] Illustrated approach to imaging and staging of nodal disease in the neck.
  • This article provides a review of the anatomic classification and staging of nodal disease in the neck through the use of tables, illustrations, and sample imaging cases.
  • The article reinforces knowledge of nodal disease in the neck while reviewing imaging examples of common and uncommon disease entities in this region.
  • We review nodal disease in the neck using American Joint Committee on Cancer staging criteria.
  • The accompanying images and clinical scenarios aid recognition with an emphasis on differential diagnosis.
  • Case examples include a broad range of pathologically and clinically proven disease entities involving lymph node disease in the neck accumulated from 1999 to 2008 at a tertiary referral center.
  • The anatomical relationships and major disease processes for this location are reviewed and illustrated with example images from commonly used imaging modalities for this region.
  • Examples of cases discussed include lymphoma, metastatic neoplasms such as head/neck squamous cell carcinoma and esthesioneuroblastoma, and inflammatory and infectious processes such as mononucleosis.
  • The reader will gain or refresh information about the anatomical relationships and demarcations of the nodal levels of the neck as well as disease entities that frequently present with neck adenopathy.
  • The images provided aid recognition with an emphasis on clinical context and differential diagnosis.
  • A succinct review of patterns of nodal disease of the neck with anatomic orientation using illustrations of typical and atypical disease entities in this region enhance and reinforce understanding of this often complex area of imaging.
  • [MeSH-major] Head and Neck Neoplasms / pathology. Head and Neck Neoplasms / radiography. Neoplasm Staging / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Carcinoma, Squamous Cell / radiography. Diagnosis, Differential. Female. Giant Lymph Node Hyperplasia / diagnosis. Humans. Lymph Nodes / anatomy & histology. Lymphatic Metastasis. Magnetic Resonance Imaging. Male. Middle Aged. Neck / anatomy & histology. Tomography, X-Ray Computed. Tongue Neoplasms / radiography

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  • [Copyright] Copyright (c) 2010 Mosby, Inc. All rights reserved.
  • (PMID = 20113867.001).
  • [ISSN] 1535-6302
  • [Journal-full-title] Current problems in diagnostic radiology
  • [ISO-abbreviation] Curr Probl Diagn Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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88. Menon S, Pai P, Sengar M, Aggarwal JP, Kane SV: Sinonasal malignancies with neuroendocrine differentiation: case series and review of literature. Indian J Pathol Microbiol; 2010 Jan-Mar;53(1):28-34
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  • Based on their neuroendocrine differentiation they can be sub categorized into sinonasal undifferentiated carcinoma (SNUC), sinonasal neuroendocrine carcinoma (SNEC), esthesioneuroblastoma (ENB) and small cell carcinoma (SmCC).
  • Hence the histo-morphological diagnosis coupled with grading/staging is important for the prognostication of these tumors.
  • Conclusion : Sino nasal tumors with neuroendocrine differentiation are a heterogenous group of tumors with overlapping histo-morphological features.
  • [MeSH-major] Carcinoma, Neuroendocrine / diagnosis. Carcinoma, Neuroendocrine / pathology. Paranasal Sinus Neoplasms / diagnosis. Paranasal Sinus Neoplasms / pathology

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  • (PMID = 20090218.001).
  • [ISSN] 0974-5130
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] India
  • [Number-of-references] 18
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89. Cossairt BM, Cummins CC: Phosphaalkenes as long-lived phosphorus cluster surface functional groups: intramolecular P=C addition to a niobium-supported P7 cage. Inorg Chem; 2008 Oct 20;47(20):9363-71
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  • When 1 is treated with aryl ketones, loss of ONb(OC[(2)Ad]Mes)3(OEt2) (2) is observed along with concomitant formation of the corresponding phosphaalkene (RC6H4)2CPP7Nb(OC[(2)Ad]Mes)3 (3-R).

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  • (PMID = 18800834.001).
  • [ISSN] 1520-510X
  • [Journal-full-title] Inorganic chemistry
  • [ISO-abbreviation] Inorg Chem
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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90. Lee JY, Kim HK: Primary olfactory neuroblastoma originating from the inferior meatus of the nasal cavity. Am J Otolaryngol; 2007 May-Jun;28(3):196-200
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  • [Title] Primary olfactory neuroblastoma originating from the inferior meatus of the nasal cavity.
  • Olfactory neuroblastoma is a rare malignant tumor of the nasal cavity arising from the olfactory neuroepithelium.
  • It usually presents as a polypoid mass high in the nasal vault including the cribriform plate, superior turbinate, and superior portion of nasal septum.
  • An 89-year-old man visited our office with symptoms of occasional left nasal bleeding and obstruction.
  • Biopsy was performed, and the diagnosis of olfactory neuroblastoma was confirmed by histopathologic examination and immunohistochemical staining.
  • The tumor was resected via medial maxillectomy, and the final pathologic report established that it was primary olfactory neuroblastoma that occurred from the inferior meatus.
  • In this report, a literature review was performed on the pathologic characteristics and prognosis of the tumor, and possible hypotheses that olfactory neuroblastoma has originated from the inferior meatus were discussed.
  • [MeSH-major] Esthesioneuroblastoma, Olfactory / pathology. Nasal Cavity / pathology. Nose Neoplasms / pathology
  • [MeSH-minor] Aged, 80 and over. Humans. Male. Neoplasm Invasiveness. Tomography, X-Ray Computed

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  • (PMID = 17499140.001).
  • [ISSN] 0196-0709
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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91. Sterzing F, Stoiber EM, Nill S, Bauer H, Huber P, Debus J, Münter MW: Intensity modulated radiotherapy (IMRT) in the treatment of children and adolescents--a single institution's experience and a review of the literature. Radiat Oncol; 2009;4:37
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  • [Title] Intensity modulated radiotherapy (IMRT) in the treatment of children and adolescents--a single institution's experience and a review of the literature.
  • This heterogeneous group of patients consisted of 20 different tumor entities, with Ewing's sarcoma being the largest (5 patients), followed by juvenile nasopharyngeal fibroma, esthesioneuroblastoma and rhabdomyosarcoma (3 patients each).

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  • (PMID = 19775449.001).
  • [ISSN] 1748-717X
  • [Journal-full-title] Radiation oncology (London, England)
  • [ISO-abbreviation] Radiat Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
  • [Number-of-references] 51
  • [Other-IDs] NLM/ PMC2760561
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92. Unger F, Haselsberger K, Walch C, Stammberger H, Papaefthymiou G: Combined endoscopic surgery and radiosurgery as treatment modality for olfactory neuroblastoma (esthesioneuroblastoma). Acta Neurochir (Wien); 2005 Jun;147(6):595-601; discussion 601-2
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  • [Title] Combined endoscopic surgery and radiosurgery as treatment modality for olfactory neuroblastoma (esthesioneuroblastoma).
  • OBJECT: Treatment of esthesioneuroblastoma (olfactory neuroblastoma) has been considerably improved by microsurgical techniques.
  • A novel therapeutic approach that combines endoscopic sinus surgery and Gamma Knife radiosurgery is presented here.
  • Taking into account the rarity of the disease the present study comprises a relatively large series of patients treated in a similar manner.
  • This series comprises 12 newly diagnosed esthesioneuroblastomas.
  • Paranasal and nasal endoscopic sinus surgery was performed.
  • All patients complained of nasal discharge and crusts.
  • CONCLUSIONS: Based on the favourable results recorded so far, the combination of endoscopic sinus surgery and radiosurgery can be considered a promising treatment option for esthesioneuroblastoma that merits further consideration.
  • [MeSH-major] Endoscopy. Esthesioneuroblastoma, Olfactory / surgery. Nasal Cavity / surgery. Nose Neoplasms / surgery. Radiosurgery
  • [MeSH-minor] Adult. Aged. Combined Modality Therapy. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Staging. Treatment Outcome


93. Yu T, Xu YK, Li L, Jia FG, Duan G, Wu YK, Li HY, Yang RM, Feng J, Ye XH, Qiu YW: Esthesioneuroblastoma methods of intracranial extension: CT and MR imaging findings. Neuroradiology; 2009 Dec;51(12):841-50
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  • [Title] Esthesioneuroblastoma methods of intracranial extension: CT and MR imaging findings.
  • INTRODUCTION: Esthesioneuroblastoma (ENB) is an aggressive neuroectodermal malignancy in the upper nasal cavity with local infiltration and lymphatic or hematogenous metastasis.
  • The primary tumors were well-defined soft-tissue masses centered in the roof of the nasal cavity eroding into the paranasal sinuses (11/11), the contralateral nasal cavity (4/11), the cranial cavity (5/11), and the fossa orbitalis (3/11).
  • CONCLUSION: Three types of direct intracranial extensions by ENB can be found on CT and MRI: cranio-orbital-nasal-communicating ENB, cranio-nasal-communicating ENB, and orbital-nasal-communicating ENB.
  • [MeSH-major] Brain Neoplasms / diagnosis. Esthesioneuroblastoma, Olfactory / diagnosis. Magnetic Resonance Imaging / methods. Nasal Cavity / diagnostic imaging. Nasal Cavity / pathology. Nose Neoplasms / diagnosis. Tomography, X-Ray Computed / methods


94. Wang XB, Pan XL, Wang TD: [Surgical approaches for sinonasal tumors with intracranial extension]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2005 May;40(5):363-5
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  • Nasofrontal bone translocation in 1 case which was a meningioma case, craniofacial approaches in 5 cases, including squamous cell carcinoma 4 cases and esthesioneuroblastoma 1 csae.
  • RESULTS: One of two meningioma cases with cavernous sinus invasion was incompletely resected, another case was resected en bloc.
  • In malignant group, ten cases were treated by nasomaxillectomy combined with frontal or infratemporal approaches.
  • The nasofrontal bone translocation is available for removal of tumors with limited intracranial extension and well developed frontal sinus.
  • [MeSH-major] Brain Neoplasms / surgery. Nose Neoplasms / surgery. Otorhinolaryngologic Surgical Procedures / methods. Paranasal Sinus Neoplasms / surgery

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  • (PMID = 16229181.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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95. Klepin HD, McMullen KP, Lesser GJ: Esthesioneuroblastoma. Curr Treat Options Oncol; 2005 Nov;6(6):509-18
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  • [Title] Esthesioneuroblastoma.
  • Esthesioneuroblastoma is a rare tumor for which the published literature does not provide an evidence-based consensus treatment approach.
  • Multimodality therapy including a combination of surgery and radiation appears to provide the best disease-free and overall survival.
  • Chemotherapy should not be used as single-modality therapy for initial treatment but may provide additional benefit when used in combination with radiation and surgery, particularly in advanced-stage disease.
  • Combination chemotherapy should be considered as initial therapy for unresectable tumors and metastatic disease, and as salvage therapy in disease recurrence.
  • [MeSH-major] Esthesioneuroblastoma, Olfactory / therapy. Nasal Cavity / pathology. Nose Neoplasms / therapy
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Combined Modality Therapy. Humans. Neoplasm Staging

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  • (PMID = 16242055.001).
  • [ISSN] 1527-2729
  • [Journal-full-title] Current treatment options in oncology
  • [ISO-abbreviation] Curr Treat Options Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 29
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96. Kutluhan A, Yilmaz N, Yakut F, Yurttaş V, Uğraş S: [Treatment of olfactory neuroblastoma via subfrontal and midfacial degloving approaches: a case report]. Kulak Burun Bogaz Ihtis Derg; 2008;18(1):56-8
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  • [Title] [Treatment of olfactory neuroblastoma via subfrontal and midfacial degloving approaches: a case report].
  • A 12-year-old girl presented with complaints of nasal obstruction and a right infraorbital swelling.
  • A biopsy obtained from the right nasal passage revealed olfactory neuroblastoma.
  • [MeSH-major] Esthesioneuroblastoma, Olfactory / surgery. Nasal Cavity / surgery. Nose Neoplasms / surgery
  • [MeSH-minor] Biopsy. Child. Female. Humans. Nasal Obstruction / etiology. Treatment Outcome

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  • (PMID = 18443406.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] tur
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Turkey
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97. Gil-Carcedo E, Gil-Carcedo LM, Vallejo LA, de Campos JM: [Esthesioneuroblastoma treatment]. Acta Otorrinolaringol Esp; 2005 Nov;56(9):389-95
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  • [Title] [Esthesioneuroblastoma treatment].
  • [Transliterated title] Tratamiento del estesioneuroblastoma. Revisión de la literatura.
  • INTRODUCTION: Esthesioneuroblastoma is an uncommon malignancy of the olfactory neuroepithelium.
  • [MeSH-major] Esthesioneuroblastoma, Olfactory / therapy. Nasal Cavity. Nose Neoplasms / therapy

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  • (PMID = 16353783.001).
  • [ISSN] 0001-6519
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 67
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98. Tselis N, Heyd R, Baghi M, Zamboglou N: Interstitial high-dose-rate-brachytherapy in advanced esthesioneuroblastoma. Laryngoscope; 2008 Nov;118(11):2006-10
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  • [Title] Interstitial high-dose-rate-brachytherapy in advanced esthesioneuroblastoma.
  • Esthesioneuroblastoma is a rare neuroectodermal tumor of the nasal vault with an aggressive biological behavior that is characterized by local recurrence, atypical distant metastasis, and poor long-term prognosis.
  • We report two cases of primary metastatic and locally recurrent disease, which were treated with computed tomography-guided interstitial high-dose-rate brachytherapy in palliative and curative intent, respectively.
  • Computed tomography-guided interstitial high-dose-rate brachytherapy should be considered as a feasible treatment option for advanced esthesioneuroblastoma.
  • [MeSH-major] Brachytherapy / methods. Esthesioneuroblastoma, Olfactory / radiotherapy. Nasal Cavity. Nose Neoplasms / radiotherapy

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  • (PMID = 18641524.001).
  • [ISSN] 1531-4995
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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99. Shapiro NL, Bhattacharyya N: Staging and survival for sinus cancer in the pediatric population. Int J Pediatr Otorhinolaryngol; 2009 Nov;73(11):1568-71
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  • [Title] Staging and survival for sinus cancer in the pediatric population.
  • OBJECTIVE: To determine histology, staging, and survival for pediatric sinus cancer.
  • METHODS: Cases of pediatric sinus cancer (maxillary, ethmoid, and frontal/sphenoid) were extracted from the Surveillance, Epidemiology, and End Results database (1988-2005).
  • RESULTS: 63 pediatric sinus cancers were identified (38 maxillary sinus, 19 ethmoid sinus, and 6 frontal/sphenoid sinus) with a mean age at diagnosis of 10.5 years and a 1:1 male to female ratio.
  • After exclusion of 11 lymphomas (17.5%), rhabdomyosarcoma was the most commonly encountered malignancy (52.0%) followed by sarcoma (17.3%) and olfactory neuroblastoma (13.5%).
  • 41.4% and 42.1% of maxillary sinus and ethmoid sinus tumors presented as T4 tumors, respectively.
  • Median survival for pediatric sinus rhabdomyosarcoma cases was estimated at 33.0 months.
  • CONCLUSIONS: Pediatric sinus malignancy commonly presents with advanced stage, and rhabdomyosarcoma is the most commonly encountered histology.
  • Due to the rarity of pediatric sinus cancer, survival estimates are difficult to obtain.
  • [MeSH-major] Paranasal Sinus Neoplasms / mortality. Paranasal Sinus Neoplasms / pathology. Rhabdomyosarcoma / mortality. Rhabdomyosarcoma / pathology
  • [MeSH-minor] Child. Female. Humans. Male. Neoplasm Staging. SEER Program. Survival Analysis

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  • (PMID = 19720405.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
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100. Ahlhelm F, Nabhan A, Naumann N, Grunwald I, Shariat K, Reith W: [Skull base tumors]. Radiologe; 2005 Sep;45(9):807-15
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  • [Transliterated title] Tumoren der Schädelbasis.
  • Modern imaging techniques have great importance in the diagnosis and therapy of skull-base pathologies.
  • Tumors commonly found in the anterior skull base include carcinoma, rhabdomyosarcoma, esthesioneuroblastoma and meningioma.
  • [MeSH-major] Image Processing, Computer-Assisted. Imaging, Three-Dimensional. Magnetic Resonance Imaging / methods. Skull Base Neoplasms / diagnosis. Tomography, Spiral Computed / methods
  • [MeSH-minor] Cerebellopontine Angle / pathology. Diagnosis, Differential. Humans. Neuroma, Acoustic / diagnosis. Neuroma, Acoustic / pathology. Sensitivity and Specificity. Skull Base / pathology

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  • (PMID = 16096741.001).
  • [ISSN] 0033-832X
  • [Journal-full-title] Der Radiologe
  • [ISO-abbreviation] Radiologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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