[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 59 of about 59
1. Chatterjee JS, Powell AP, Chatterjee D: Pleomorphic rhabdomyosarcoma of the diaphragm. J Natl Med Assoc; 2005 Jan;97(1):95-8
The Weizmann Institute of Science GeneCards and MalaCards databases. gene/protein/disease-specific - MalaCards for pleomorphic rhabdomyosarcoma .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pleomorphic rhabdomyosarcoma of the diaphragm.
  • Pleomorphic rhabdomyosarcoma of the diaphragm represents fewer than 0.0001% of all cancers.
  • It is an adult disease of both sexes, the lowest reported age being 14 years.
  • Early diagnosis and wide excision are essential along with radiotherapy and chemotherapy before any survival--much less worthwhile survival--can be hoped for.
  • [MeSH-major] Diaphragm. Muscle Neoplasms. Rhabdomyosarcoma
  • [MeSH-minor] Adult. Humans. Male

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Cancer. 1958 Jan-Feb;11(1):1-3 [13500286.001]
  • [Cites] Surgery. 1952 Dec;32(6):1023-64 [13005336.001]
  • [Cites] J Bone Joint Surg Am. 1965 Jun;47:715-26 [14299664.001]
  • [Cites] J Pediatr. 1959 Nov;55:620-34 [13803494.001]
  • [Cites] Rev Hosp Clin Fac Med Sao Paulo. 2002 Mar-Apr;57(2):67-72 [11981587.001]
  • [Cites] Cancer. 1968 Nov;22(5):956-67 [5686645.001]
  • [Cites] Am J Gastroenterol. 1971 Dec;56(6):555-8 [5134884.001]
  • [Cites] Pathol Annu. 1972;7:81-106 [4557937.001]
  • [Cites] Indian J Cancer. 1972 Mar;9(1):42-9 [5044708.001]
  • [Cites] Ann Med Interne (Paris). 1972 Feb;123(2):181-5 [5055075.001]
  • [Cites] Wien Z Inn Med. 1973;54(2):78-84 [4588077.001]
  • [Cites] Cancer. 1975 Aug;36(2):759-64 [1157035.001]
  • [Cites] Tumori. 1975 Mar-Apr;61(2):129-50 [1226574.001]
  • [Cites] J Natl Med Assoc. 1988 Feb;80(2):214-7 [3071608.001]
  • [Cites] Am J Surg Pathol. 1998 Apr;22(4):459-64 [9537474.001]
  • [Cites] Surgery. 1962 Oct;52:572-84 [14484432.001]
  • (PMID = 15719879.001).
  • [ISSN] 1943-4693
  • [Journal-full-title] Journal of the National Medical Association
  • [ISO-abbreviation] J Natl Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 29
  • [Other-IDs] NLM/ PMC2568583
  •  go-up   go-down


2. Borka K, Patai K, Rendek A, Sobel G, Paulin F: Pleomorphic rhabdomyosarcoma of the uterus in a postmenopausal patient. Pathol Oncol Res; 2006;12(2):102-4
Hazardous Substances Data Bank. DOXORUBICIN .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pleomorphic rhabdomyosarcoma of the uterus in a postmenopausal patient.
  • Pure rhabdomyosarcomas occurring in the adult uterus are very rare, with poor prognosis.
  • We present a case of a 67-year-old woman with postmenopausal vaginal bleeding caused by pleomorphic rhabdomyosarcoma of the uterus, treated with hysterectomy, bilateral salpingo-oophorectomy, pelvic/paraaortic lymphadenectomy and partial sigmoidectomy.
  • [MeSH-major] Postmenopause / physiology. Rhabdomyosarcoma. Uterine Neoplasms
  • [MeSH-minor] Aged. Antibiotics, Antineoplastic / administration & dosage. Combined Modality Therapy. Diagnosis. Doxorubicin / administration & dosage. Female. Humans. Prognosis. Uterine Hemorrhage / etiology. Uterine Hemorrhage / physiopathology

  • MedlinePlus Health Information. consumer health - Uterine Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16799711.001).
  • [ISSN] 1219-4956
  • [Journal-full-title] Pathology oncology research : POR
  • [ISO-abbreviation] Pathol. Oncol. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 80168379AG / Doxorubicin
  •  go-up   go-down


3. Vyas V, Al Awadi S, Nemec J, El Khodary A, Francis IM, Muralidharan KC, Delvadiya MD: Primary mediastinal pleomorphic rhabdomyosarcoma: a case report. Med Princ Pract; 2008;17(2):154-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary mediastinal pleomorphic rhabdomyosarcoma: a case report.
  • OBJECTIVE: To report a rare case of pleomorphic rhabdomyosarcoma which occurred in the mediastinum of a 34-year-old man.
  • His alpha-fetoprotein was 22,000 IU/l; based on this the diagnosis of a germ cell tumour was made and the patient was treated with a bleomycin/etoposide/cisplatin regimen.
  • He left for his native country where an open biopsy from the mediastinum was taken and reported as pleomorphic rhabdomyosarcoma.
  • [MeSH-major] Mediastinal Neoplasms. Neoplasms, Germ Cell and Embryonal. Rhabdomyosarcoma. Teratoma
  • [MeSH-minor] Adult. Combined Modality Therapy. Drug Resistance, Neoplasm. Humans. Male

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2008 S. Karger AG, Basel.
  • (PMID = 18287801.001).
  • [ISSN] 1423-0151
  • [Journal-full-title] Medical principles and practice : international journal of the Kuwait University, Health Science Centre
  • [ISO-abbreviation] Med Princ Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
  •  go-up   go-down


Advertisement
4. Tsai WC, Lee SS, Cheng MF, Lee HS: Botryoid-type pleomorphic rhabdomyosarcoma of the renal pelvis in an adult. A rare case report and review of the literature. Urol Int; 2006;77(1):89-91
The Weizmann Institute of Science GeneCards and MalaCards databases. gene/protein/disease-specific - MalaCards for pleomorphic rhabdomyosarcoma .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Botryoid-type pleomorphic rhabdomyosarcoma of the renal pelvis in an adult. A rare case report and review of the literature.
  • Rhabdomyosarcoma of the renal pelvis is an extremely rare lesion for which only two reports are available.
  • Here, we report another case of botryoid-type pleomorphic rhabdomyosarcoma in the renal pelvis.
  • Although rhabdomyosarcoma has formerly been reported to occur at the renal pelvis, to our knowledge, this is the first case of renal pelvis botryoid-type pleomorphic rhabdomyosarcoma diagnosed by light microscopy and immunohistochemical stains.
  • [MeSH-major] Kidney Neoplasms / pathology. Kidney Pelvis. Rhabdomyosarcoma / pathology

  • MedlinePlus Health Information. consumer health - Kidney Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16825824.001).
  • [ISSN] 0042-1138
  • [Journal-full-title] Urologia internationalis
  • [ISO-abbreviation] Urol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 9
  •  go-up   go-down


5. Croes R, Debiec-Rychter M, Cokelaere K, De Vos R, Hagemeijer A, Sciot R: Adult sclerosing rhabdomyosarcoma: cytogenetic link with embryonal rhabdomyosarcoma. Virchows Arch; 2005 Jan;446(1):64-7
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adult sclerosing rhabdomyosarcoma: cytogenetic link with embryonal rhabdomyosarcoma.
  • Rhabdomyosarcomas are classified into three well-defined categories: embryonal, alveolar and pleomorphic rhabdomyosarcoma.
  • Recently, seven cases of an unusual adult type of rhabdomyosarcoma with a prominent hyaline sclerosis have been described.
  • We report the hitherto unreported cytogenetic changes of an adult sclerosing rhabdomyosarcoma.
  • Using fluorescent in situ hybridization (FISH) analysis, the tumor cells were negative for FOXO1A-disrupting translocations specific for alveolar rhabdomyosarcoma.
  • The chromosomal composition of malignant cells resembled the pattern of numerical changes frequently observed in embryonal rhabdomyosarcoma, suggesting a close relationship of an adult sclerosing rhabdomyosarcoma with this entity.
  • [MeSH-major] Rhabdomyosarcoma / genetics. Rhabdomyosarcoma, Embryonal / genetics. Translocation, Genetic

  • Genetic Alliance. consumer health - Rhabdomyosarcoma embryonal.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15660283.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


6. Pittore B, Fancello G, Cossu Rocca P, Ledda GP, Tore G: Rhabdomyosarcoma: a rare laryngeal neoplastic entity. Acta Otorhinolaryngol Ital; 2010 Feb;30(1):52-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rhabdomyosarcoma: a rare laryngeal neoplastic entity.
  • A case of pleomorphic rhabdomyosarcoma of the larynx is presented, which is extremely rare in a laryngeal site.
  • The symptomatology and macroscopic aspect of the neoplasm can simulate the presence of other neoplastic variants of the larynx, and, for this reason, histological examination must be associated with immunohistochemistry for correct diagnosis and treatment.
  • [MeSH-major] Laryngeal Neoplasms. Rhabdomyosarcoma

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Ann Afr Med. 2007 Dec;6(4):190-3 [18354945.001]
  • [Cites] BMC Cancer. 2007;7:177 [17854490.001]
  • [Cites] J Clin Oncol. 1999 Nov;17(11):3468-75 [10550144.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 2000 Apr;126(4):468-72 [10772299.001]
  • [Cites] Cancer. 2001 Feb 1;91(3):606-12 [11169945.001]
  • [Cites] Cancer. 2001 Feb 15;91(4):794-803 [11241248.001]
  • [Cites] J Clin Oncol. 2001 Jun 15;19(12):3091-102 [11408506.001]
  • [Cites] Oral Oncol. 2002 Jul;38(5):450-9 [12110339.001]
  • [Cites] Cancer. 2002 Jul 15;95(2):377-88 [12124838.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 2004 Oct;130(10):1217-22 [15492173.001]
  • [Cites] Laryngoscope. 1970 Nov;80(11):1733-9 [5481003.001]
  • [Cites] Arch Otolaryngol. 1976 Feb;102(2):104-7 [1247416.001]
  • [Cites] J Laryngol Otol. 1976 Jul;90(7):687-98 [956708.001]
  • [Cites] J Laryngol Otol. 1978 May;92(5):417-24 [650071.001]
  • [Cites] Cancer. 1982 Jun 1;49(11):2217-21 [7074538.001]
  • [Cites] Cancer. 1984 Feb 15;53(4):1016-9 [6692285.001]
  • [Cites] Cancer. 1987 Mar 1;59(5):1012-8 [3815260.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 1987 Nov;113(11):1225-7 [3663351.001]
  • [Cites] Cancer. 1988 Jan 15;61(2):209-20 [3275486.001]
  • [Cites] Cancer. 1993 Mar 1;71(5):1904-22 [8448756.001]
  • [Cites] J Clin Oncol. 1995 Mar;13(3):610-30 [7884423.001]
  • [Cites] Int J Pediatr Otorhinolaryngol. 1995 Jan;31(1):15-22 [7729989.001]
  • [Cites] Ann Otol Rhinol Laryngol. 1996 Apr;105(4):289-94 [8604891.001]
  • [Cites] Eur Arch Otorhinolaryngol. 1998;255(6):307-10 [9693927.001]
  • [Cites] J Laryngol Otol. 1998 Jul;112(7):670-2 [9775303.001]
  • [Cites] Cancer. 2005 Apr 1;103(7):1475-83 [15712283.001]
  • [Cites] Otolaryngol Head Neck Surg. 2005 Jul;133(1):160-2 [16025073.001]
  • [Cites] Acta Med Croatica. 2006 Jun;60(3):255-7 [16933839.001]
  • [Cites] Auris Nasus Larynx. 2007 Dec;34(4):553-6 [17481838.001]
  • [Cites] Pediatr Radiol. 2008 Jun;38(6):617-34 [18324394.001]
  • (PMID = 20559474.001).
  • [ISSN] 1827-675X
  • [Journal-full-title] Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale
  • [ISO-abbreviation] Acta Otorhinolaryngol Ital
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2881606
  • [Keywords] NOTNLM ; Larynx / Malignant tumours / Pleomorphic rhabdomyosarcoma / Prognostic factors
  •  go-up   go-down


7. Tufail M, Rizwan MM, Majid HJ: Pleomorphic rhabdomyosarcoma within a choledochal cyst; a rare cause of obstructive jaundice. J Pak Med Assoc; 2006 Aug;56(8):379-81
MedlinePlus Health Information. consumer health - Bile Duct Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pleomorphic rhabdomyosarcoma within a choledochal cyst; a rare cause of obstructive jaundice.
  • The long term complication of choledochal cysts includes malignant transformation in the epithelial lining of biliary tree.
  • However, Rhabdomyosarcoma associated with choledochal cyst in an adult is rarely reported before.
  • The authors report one such case in an adult female patient who presented to us with features of obstructive jaundice.
  • [MeSH-major] Bile Duct Neoplasms / complications. Choledochal Cyst / complications. Jaundice, Obstructive / etiology. Rhabdomyosarcoma / complications

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16967793.001).
  • [ISSN] 0030-9982
  • [Journal-full-title] JPMA. The Journal of the Pakistan Medical Association
  • [ISO-abbreviation] J Pak Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
  •  go-up   go-down


8. Goldstein M, Meller I, Issakov J, Orr-Urtreger A: Novel genes implicated in embryonal, alveolar, and pleomorphic rhabdomyosarcoma: a cytogenetic and molecular analysis of primary tumors. Neoplasia; 2006 May;8(5):332-43
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Novel genes implicated in embryonal, alveolar, and pleomorphic rhabdomyosarcoma: a cytogenetic and molecular analysis of primary tumors.
  • Rhabdomyosarcoma, the most common pediatric soft tissue sarcoma, likely results from deregulation of the skeletal myogenesis program.
  • Using a combined approach of spectral karyotyping, array-based comparative genomic hybridization (CGH), and expression analysis, we examined 10 primary RMS tumors, including embryonal, alveolar, and the rare adult pleomorphic variant, to explore the involvement of different genes and genetic pathways in RMS tumorigenesis.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Genetic Predisposition to Disease. Neoplasms / genetics. Rhabdomyosarcoma, Alveolar / genetics. Rhabdomyosarcoma, Alveolar / metabolism. Rhabdomyosarcoma, Embryonal / embryology. Rhabdomyosarcoma, Embryonal / genetics
  • [MeSH-minor] Adolescent. Adult. Aged. Cell Adhesion. Child. Child, Preschool. Cytoskeleton / metabolism. Female. Gene Expression Regulation, Neoplastic. Humans. Infant. Karyotyping. Lung Neoplasms / metabolism. Male. Nucleic Acid Hybridization

  • Genetic Alliance. consumer health - Rhabdomyosarcoma alveolar.
  • Genetic Alliance. consumer health - Rhabdomyosarcoma embryonal.
  • MedlinePlus Health Information. consumer health - Cancer in Children.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Biol Chem. 2001 Oct 5;276(40):37307-16 [11489882.001]
  • [Cites] Int J Cancer. 2006 Jun 1;118(11):2772-81 [16381018.001]
  • [Cites] Oncogene. 2001 Sep 10;20(40):5736-46 [11607823.001]
  • [Cites] Am J Physiol Cell Physiol. 2002 Feb;282(2):C383-94 [11788350.001]
  • [Cites] Genes Chromosomes Cancer. 2002 Mar;33(3):310-21 [11807989.001]
  • [Cites] EMBO J. 2002 Feb 15;21(4):483-92 [11847097.001]
  • [Cites] J Pathol. 2002 Apr;196(4):450-8 [11920742.001]
  • [Cites] Oncogene. 2002 Apr 25;21(18):2901-7 [11973651.001]
  • [Cites] Cytogenet Cell Genet. 2001;95(3-4):134-42 [12063389.001]
  • [Cites] Jpn J Cancer Res. 2002 Jun;93(6):652-9 [12079513.001]
  • [Cites] Oncogene. 2002 Sep 9;21(40):6175-83 [12214247.001]
  • [Cites] Mol Cell Biol. 2002 Oct;22(20):7204-16 [12242297.001]
  • [Cites] Cancer Res. 2002 Dec 1;62(23):6803-7 [12460888.001]
  • [Cites] Cancer Genet Cytogenet. 2003 Jan 1;140(1):73-7 [12550764.001]
  • [Cites] Biol Cell. 2002 Nov;94(7-8):535-43 [12566226.001]
  • [Cites] Cancer Genet Cytogenet. 2003 Mar;141(2):120-7 [12606129.001]
  • [Cites] Biochem J. 2003 Apr 1;371(Pt 1):211-21 [12519076.001]
  • [Cites] J Cell Biol. 2003 Apr 14;161(1):197-209 [12695504.001]
  • [Cites] Matrix Biol. 2003 Mar;22(1):49-54 [12714041.001]
  • [Cites] Br J Cancer. 2003 Jul 21;89(2):327-32 [12865925.001]
  • [Cites] Annu Rev Biochem. 2003;72:743-81 [12676796.001]
  • [Cites] Clin Cancer Res. 2003 Nov 1;9(14):5271-81 [14614009.001]
  • [Cites] Cancer Genet Cytogenet. 2004 Jan 1;148(1):35-43 [14697639.001]
  • [Cites] Physiol Rev. 2004 Jan;84(1):209-38 [14715915.001]
  • [Cites] Cancer Res. 1989 Oct 1;49(19):5407-13 [2766305.001]
  • [Cites] Cancer Res. 1991 Oct 1;51(19):5100-6 [1717137.001]
  • [Cites] Cancer. 1994 Apr 15;73(8):2231-7 [8156531.001]
  • [Cites] Am J Clin Pathol. 1995 Dec;104(6):627-33 [8526204.001]
  • [Cites] Cytogenet Cell Genet. 1996;73(4):325-30 [8751388.001]
  • [Cites] Hum Mol Genet. 1996 Jan;5(1):15-21 [8789435.001]
  • [Cites] Med Pediatr Oncol. 1998 Mar;30(3):156-9 [9434823.001]
  • [Cites] Genes Chromosomes Cancer. 1998 May;22(1):16-25 [9591630.001]
  • [Cites] EMBO J. 1998 Jun 1;17(11):3052-65 [9606188.001]
  • [Cites] Nat Genet. 1998 Oct;20(2):189-93 [9771714.001]
  • [Cites] Oncogene. 1999 Sep 20;18(38):5340-8 [10498887.001]
  • [Cites] Nat Rev Cancer. 2005 Jan;5(1):42-50 [15630414.001]
  • [Cites] Cancer Res. 2005 Apr 1;65(7):2899-905 [15805292.001]
  • [Cites] Gene. 2005 Mar 28;348:65-71 [15777710.001]
  • [Cites] Genes Chromosomes Cancer. 1999 Dec;26(4):275-85 [10534762.001]
  • [Cites] Neoplasia. 1999 Aug;1(3):262-75 [10935481.001]
  • [Cites] Cancer Genet Cytogenet. 2000 Sep;121(2):139-45 [11063797.001]
  • [Cites] J Biol Chem. 2000 Nov 17;275(46):36238-44 [10945974.001]
  • [Cites] Med Pediatr Oncol. 2001 Feb;36(2):259-67 [11452933.001]
  • [Cites] Br J Cancer. 2001 Sep 14;85(6):831-5 [11556833.001]
  • [Cites] Am J Clin Pathol. 2004 Mar;121(3):358-65 [15023040.001]
  • [Cites] Cancer Genet Cytogenet. 2004 May;151(1):73-7 [15120913.001]
  • [Cites] Cancer Res. 2004 Jul 1;64(13):4428-33 [15231651.001]
  • [Cites] Nat Genet. 2004 Nov;36(11):1159-61 [15475955.001]
  • [Cites] J Natl Cancer Inst. 1973 Nov;51(5):1417-23 [4357758.001]
  • [Cites] Hum Pathol. 1985 Aug;16(8):838-43 [4018780.001]
  • [Cites] Nature. 1985 Nov 7-13;318(6041):69-73 [2997622.001]
  • [Cites] Cancer Res. 1987 Aug 15;47(16):4501-7 [3607778.001]
  • [Cites] Cytogenet Cell Genet. 1987;45(3-4):148-55 [3691179.001]
  • [Cites] Cancer Res. 1988 Feb 15;48(4):983-7 [3338090.001]
  • [Cites] Cancer Genet Cytogenet. 2005 May;159(1):10-7 [15860351.001]
  • [Cites] Cancer Genet Cytogenet. 2005 Dec;163(2):138-43 [16337856.001]
  • [Cites] Clin Exp Metastasis. 2000;18(6):439-43 [11592300.001]
  • (PMID = 16790082.001).
  • [ISSN] 1476-5586
  • [Journal-full-title] Neoplasia (New York, N.Y.)
  • [ISO-abbreviation] Neoplasia
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Canada
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ PMC1592451
  •  go-up   go-down


9. Tsumura H, Yoshida T, Saito H, Imanaka-Yoshida K, Suzuki N: Cooperation of oncogenic K-ras and p53 deficiency in pleomorphic rhabdomyosarcoma development in adult mice. Oncogene; 2006 Dec 14;25(59):7673-9
SciCrunch. Marmoset Gene list: Data: Gene Annotation .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cooperation of oncogenic K-ras and p53 deficiency in pleomorphic rhabdomyosarcoma development in adult mice.
  • The tumor histology was pleomorphic RMS with characteristic bizarre giant cells, positive for desmin and alpha-sarcomeric actin and exhibiting remarkable increase in total and phosphorylated extracellular signal-regulated protein kinase (ERK)1 and ERK2.
  • Loss of the wild-type p53 was detected in K-rasG12V-expressed tumors of p53(-/+) mice.
  • Thus, cooperation of oncogenic K-ras and p53 deficiency resulted in the development of pleomorphic RMS in adult mice, providing a useful mouse model for further detailed studies.
  • [MeSH-major] Genes, p53 / physiology. Genes, ras / physiology. Rhabdomyosarcoma / etiology


10. Amin RM, Kokubo T, Hiroshima K, Narita M, Itou K, Kuroki M, Tanizawa T, Nakatani Y: Metastatic germ cell tumor of the lung masquerading as primary rhabdomyosarcoma. Pathol Int; 2005 Oct;55(10):649-54
MedlinePlus Health Information. consumer health - Testicular Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastatic germ cell tumor of the lung masquerading as primary rhabdomyosarcoma.
  • Two years after testicular resection was carried out in a 40-year-old man that revealed mixed germ cell tumor of more than one histological type (seminoma, embryonal cell carcinoma, and yolk sac tumor), he presented with an asymptomatic pulmonary nodule in his left lower lobe.
  • Video-assisted thoracoscopic partial resection of the tumor revealed a 24 x 20 mm teratoma with somatic-type malignancy in which pleomorphic rhabdomyosarcoma was a major element.
  • One year later, asymptomatic tumor recurrence occurred at both edges of the stapler line as 22 x 20 mm and 10 x 5 mm nodules composed only of pleomorphic rhabdomyosarcoma.
  • In conclusion, despite the fact that primary pulmonary rhabdromyosarcoma is a rare neoplasm, metastatic pulmonary germ cell tumor with somatic-type malignancy showing predominantly rhabdomyosarcomatous differentiation should be considered in the differential diagnosis of such lesions of the lung.
  • [MeSH-major] Lung Neoplasms / diagnosis. Neoplasms, Germ Cell and Embryonal / diagnosis. Rhabdomyosarcoma / diagnosis. Testicular Neoplasms / diagnosis
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Chemotherapy, Adjuvant. Combined Modality Therapy. Diagnosis, Differential. Humans. Immunoenzyme Techniques. Male. Neoplasm Recurrence, Local. Tomography, X-Ray Computed

  • MedlinePlus Health Information. consumer health - Lung Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16185296.001).
  • [ISSN] 1320-5463
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down


11. Demiralp B, Ozdemir MT, Erler K, Basbozkurt M: Type 1 neurofibromatosis and adult extremity sarcoma. A report of two cases. Acta Orthop Belg; 2007 Jun;73(3):403-7
Genetic Alliance. consumer health - Neurofibromatosis type 1.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Type 1 neurofibromatosis and adult extremity sarcoma. A report of two cases.
  • We report two cases of malignant soft-tissue tumours--one myxoid malignant fibrous histiocytoma and one pleomorphic rhabdomyosarcoma--which were diagnosed in two young adult patients with type 1 neurofibromatosis (NF 1).
  • Diagnoses of myxoid malignant fibrous histiocytoma and pleomorphic rhabdomyosarcoma in adult NF 1 patients are exceedingly rare.
  • Thus detection of subtypes of rhabdomyosarcoma and malignant fibrous histiocytoma with immunohistochemistry may be helpful for the management of these tumours among other pleomorphic sarcomas that may occur in type 1 Neurofibromatosis.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / complications. Neoplasms, Multiple Primary. Neurofibromatosis 1 / complications. Rhabdomyosarcoma / complications. Soft Tissue Neoplasms
  • [MeSH-minor] Adult. Humans. Male

  • Genetic Alliance. consumer health - Neurofibromatosis.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17715736.001).
  • [ISSN] 0001-6462
  • [Journal-full-title] Acta orthopaedica Belgica
  • [ISO-abbreviation] Acta Orthop Belg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
  •  go-up   go-down


12. Stock N, Chibon F, Binh MB, Terrier P, Michels JJ, Valo I, Robin YM, Guillou L, Ranchère-Vince D, Decouvelaere AV, Collin F, Birtwisle-Peyrottes I, Gregoire F, Aurias A, Coindre JM: Adult-type rhabdomyosarcoma: analysis of 57 cases with clinicopathologic description, identification of 3 morphologic patterns and prognosis. Am J Surg Pathol; 2009 Dec;33(12):1850-9
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adult-type rhabdomyosarcoma: analysis of 57 cases with clinicopathologic description, identification of 3 morphologic patterns and prognosis.
  • Adult-type rhabdomyosarcoma (RMS) has been classically defined as a pleomorphic sarcoma with desmin expression occurring in adult patients.
  • Cases were classified in 3 histologic categories: spindle cell RMS (25 cases), pleomorphic RMS (16 cases), and mixed type (16 cases).
  • In conclusion, adult-type RMS is a rare sarcoma occurring mainly in the extremities and trunk wall with 2 main histologic patterns, spindle cell, and pleomorphic patterns, which represent the end of the spectrum of a single entity.
  • [MeSH-major] Rhabdomyosarcoma / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / analysis. Biomarkers, Tumor / genetics. Comparative Genomic Hybridization. Diagnosis, Differential. Disease-Free Survival. Female. Gene Expression Regulation, Neoplastic. Humans. Immunohistochemistry. Immunophenotyping. In Situ Hybridization, Fluorescence. Kaplan-Meier Estimate. Male. Middle Aged. Neoplasm Recurrence, Local. Neoplasm Staging. Predictive Value of Tests. Time Factors. Treatment Outcome. Young Adult

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19898221.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down


13. Goldstein M, Meller I, Orr-Urtreger A: FGFR1 over-expression in primary rhabdomyosarcoma tumors is associated with hypomethylation of a 5' CpG island and abnormal expression of the AKT1, NOG, and BMP4 genes. Genes Chromosomes Cancer; 2007 Nov;46(11):1028-38
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] FGFR1 over-expression in primary rhabdomyosarcoma tumors is associated with hypomethylation of a 5' CpG island and abnormal expression of the AKT1, NOG, and BMP4 genes.
  • Rhabdomyosarcoma (RMS), the most common pediatric soft tissue sarcoma likely results from abnormal proliferation and differentiation during skeletal myogenesis.
  • Multiple genetic alterations are associated with the three RMS histopathological subtypes, embryonal, alveolar, and pleomorphic adult variant.
  • [MeSH-major] Bone Morphogenetic Proteins / genetics. Carrier Proteins / genetics. CpG Islands. DNA Methylation. Proto-Oncogene Proteins c-akt / genetics. Receptor, Fibroblast Growth Factor, Type 1 / genetics. Rhabdomyosarcoma / genetics

  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright (c) 2007 Wiley-Liss, Inc.
  • (PMID = 17696196.001).
  • [ISSN] 1045-2257
  • [Journal-full-title] Genes, chromosomes & cancer
  • [ISO-abbreviation] Genes Chromosomes Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / BMP4 protein, human; 0 / Bone Morphogenetic Protein 4; 0 / Bone Morphogenetic Proteins; 0 / Carrier Proteins; 0 / DNA Primers; 148294-77-3 / noggin protein; EC 2.7.10.1 / FGFR1 protein, human; EC 2.7.10.1 / Receptor, Fibroblast Growth Factor, Type 1; EC 2.7.11.1 / AKT1 protein, human; EC 2.7.11.1 / Proto-Oncogene Proteins c-akt
  •  go-up   go-down


14. Schrock A, Jakob M, Zhou H, Bootz F: Laryngeal pleomorphic rhabdomyosarcoma. Auris Nasus Larynx; 2007 Dec;34(4):553-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laryngeal pleomorphic rhabdomyosarcoma.
  • Adult rhabdomyosarcoma of the larynx is a rare disease.
  • Two cases of laryngeal rhabdomyosarcoma of the pleomorphic subtype are presented.
  • The pathology of the tumor, diagnosis, and treatment are discussed.
  • [MeSH-major] Hoarseness / etiology. Laryngeal Neoplasms / diagnosis. Rhabdomyosarcoma / diagnosis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17481838.001).
  • [ISSN] 0385-8146
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  •  go-up   go-down


15. Al-Daraji WI, Makhlouf HR, Miettinen M, Montgomery EA, Goodman ZD, Marwaha JS, Fanburg-Smith JC: Primary gallbladder sarcoma: a clinicopathologic study of 15 cases, heterogeneous sarcomas with poor outcome, except pediatric botryoid rhabdomyosarcoma. Am J Surg Pathol; 2009 Jun;33(6):826-34
MedlinePlus Health Information. consumer health - Soft Tissue Sarcoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary gallbladder sarcoma: a clinicopathologic study of 15 cases, heterogeneous sarcomas with poor outcome, except pediatric botryoid rhabdomyosarcoma.
  • BACKGROUND: Primary gallbladder sarcoma (PGBS) is rare, with only 39 documented cases, with the predominant type being leiomyosarcoma.
  • RESULT: PGBS occurred in 4 males and 11 females with the adult median age of 68.5 (range: 24 to 88 y, n=12) and 3 children ages 1.5 to 3 years, the latter all with botryoid embryonal rhabdomyosarcoma.
  • PGBSs were diagnosed as 7 myxofibrosarcomas [malignant fibrous histiocytoma, storiform pleomorphic to myxoid, 2 with an unusual fibromyxoid sarcoma-like (Evans-like), and pleomorphic hyalinizing angiectatic tumor-like mixture], 2 leiomyosarcomas, 1 gastrointestinal stromal tumor-like (GIST-like), 3 botryoid embryonal rhabdomyosarcomas (RMS), and 2 epithelioid angiosarcomas.
  • Diagnosis was based on morphology and immunohistochemistry.
  • A diagnosis of LMS required myoid-intersecting fascicles and diffuse, strong immunoreactivity for smooth muscle actin +/- desmin.
  • Follow-up of 12 revealed that 7 patients died of disease within 3 weeks to 1 year and 4 months after diagnosis, 3 died of unknown causes, and 2, both adjuvant therapy treated botryoid RMS in young children, were alive without disease 11 and 27 years later.
  • A variety of sarcoma types are found, yet malignant fibrous histiocytoma is the predominant variant, more common than LMS.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Child, Preschool. Female. Humans. Immunohistochemistry. Infant. Male. Middle Aged. Prognosis

  • MedlinePlus Health Information. consumer health - Gallbladder Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19194282.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


16. Hartmann JT: Systemic treatment options for patients with refractory adult-type sarcoma beyond anthracyclines. Anticancer Drugs; 2007 Mar;18(3):245-54
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Systemic treatment options for patients with refractory adult-type sarcoma beyond anthracyclines.
  • Small round cell sarcoma, such as Ewing/PNET, desmoplastic small round cell sarcoma and rhabdomyosarcoma, are chemotherapy-sensitive and potentially curable malignancies, which are treated with multimodality, dose-intensitive and neoadjuvant protocols regardless of size or overt metastatic disease.
  • A limited number of effective agents available for the treatment of patients with metastatic adult soft-tissue sarcoma exists, which have failed anthracyline and ifosfamide-based chemotherapy.
  • Most other high-grade (grading >I) so-called adult-type soft-tissue sarcomas such as fibro, lipo, pleomorphic and synovial sarcoma are treated with a anthracycline-based regimen with or without ifosfamide as front-line therapy.
  • In relapsed 'adult-type' soft-tissue sarcomas trofosfamide, gemcitabine and ecteinascidin (ET-743) appear to be drugs associated with moderate activity and an acceptable toxicity profile.

  • MedlinePlus Health Information. consumer health - Cancer Chemotherapy.
  • MedlinePlus Health Information. consumer health - Soft Tissue Sarcoma.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17264755.001).
  • [ISSN] 0959-4973
  • [Journal-full-title] Anti-cancer drugs
  • [ISO-abbreviation] Anticancer Drugs
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Alkylating Agents; 0 / Anthracyclines; 0 / Antimetabolites; 0 / Antineoplastic Agents; 0 / DNA, Neoplasm; 0 / Enzyme Inhibitors; 0 / Taxoids; 0 / Topoisomerase I Inhibitors; EC 2.1.1.45 / Thymidylate Synthase; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; EC 2.7.10.1 / Receptors, Platelet-Derived Growth Factor; EC 2.7.10.1 / Receptors, Vascular Endothelial Growth Factor
  • [Number-of-references] 91
  •  go-up   go-down


17. Bahrami A, Folpe AL: Adult-type fibrosarcoma: A reevaluation of 163 putative cases diagnosed at a single institution over a 48-year period. Am J Surg Pathol; 2010 Oct;34(10):1504-13
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adult-type fibrosarcoma: A reevaluation of 163 putative cases diagnosed at a single institution over a 48-year period.
  • Adult-type fibrosarcoma (FS) was once considered the most common adult sarcoma, but is now considered a diagnosis of exclusion.
  • One hundred ninety-five cases diagnosed as adult FS in somatic soft tissue were retrieved from our institutional archives for the period 1960 to 2008.
  • Revised diagnoses were based on clinical, morphologic, IHC, and molecular findings.
  • Non-FS (137 cases) were reclassified as: undifferentiated pleomorphic sarcoma (32 cases), SS (21 cases), solitary fibrous tumor (14 cases), myxofibrosarcoma (11 cases), malignant peripheral nerve sheath tumor (8 cases), FS dermatofibrosarcoma protuberans, and desmoplastic melanoma (4 cases each), low-grade fibromyxoid sarcoma, sarcomatoid carcinoma, desmoid-type fibromatosis, rhabdomyosarcoma, myofibroblastic sarcoma, spindle-cell liposarcoma (3 cases each), sclerosing epithelioid FS, fibroma-like epithelioid sarcoma, leiomyosarcoma, cellular fibrous histiocytoma (2 cases each), and others (17 cases).
  • Exclusive of undifferentiated pleomorphic sarcoma, the distinction of which from FS is subjective, 64% of putative FS were reclassified, most commonly as monophasic SS and solitary fibrous tumor.
  • We conclude that true FS is exceedingly rare, accounting for <1% of approximately 10,000 adult soft tissue sarcomas seen at our institution during this time period, and should be diagnosed with great caution.
  • [MeSH-major] Fibrosarcoma / diagnosis. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Adult. Age Factors. Aged. Aged, 80 and over. Biomarkers, Tumor / metabolism. Child. Child, Preschool. DNA, Neoplasm / analysis. Female. Gene Rearrangement. Humans. In Situ Hybridization, Fluorescence. Male. Middle Aged. Minnesota / epidemiology. Proto-Oncogene Proteins / genetics. Proto-Oncogene Proteins / metabolism. Repressor Proteins / genetics. Repressor Proteins / metabolism. Young Adult

  • Genetic Alliance. consumer health - Fibrosarcoma.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20829680.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Neoplasm; 0 / Proto-Oncogene Proteins; 0 / Repressor Proteins; 0 / SS18 protein, human
  •  go-up   go-down


18. Kopp HG, Patel S, Brücher B, Hartmann JT: Potential combination chemotherapy approaches for advanced adult-type soft-tissue sarcoma. Am J Clin Dermatol; 2008;9(4):207-17
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Potential combination chemotherapy approaches for advanced adult-type soft-tissue sarcoma.
  • However, a few subtypes, such as small round-cell tumors and rhabdomyosarcoma (other than pleomorphic), are considered chemotherapy sensitive.
  • [MeSH-minor] Adult. Angiogenesis Inhibitors / administration & dosage. Anthracyclines / administration & dosage. Antibodies, Monoclonal / administration & dosage. Humans. Neoplasm Staging. Protein Kinase Inhibitors / administration & dosage

  • Genetic Alliance. consumer health - Soft tissue sarcoma.
  • MedlinePlus Health Information. consumer health - Soft Tissue Sarcoma.
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18572972.001).
  • [ISSN] 1175-0561
  • [Journal-full-title] American journal of clinical dermatology
  • [ISO-abbreviation] Am J Clin Dermatol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] New Zealand
  • [Chemical-registry-number] 0 / Angiogenesis Inhibitors; 0 / Anthracyclines; 0 / Antibodies, Monoclonal; 0 / Protein Kinase Inhibitors
  • [Number-of-references] 108
  •  go-up   go-down


19. Dalfior D, Eccher A, Gobbo S, Brunelli M, Martignoni G, Menestrina F, Dalla PP, Dvornik G: Primary pleomorphic rhabdomyosarcoma of the kidney in an adult. Ann Diagn Pathol; 2008 Aug;12(4):301-3
MedlinePlus Health Information. consumer health - Kidney Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary pleomorphic rhabdomyosarcoma of the kidney in an adult.
  • Sarcoma of the kidney is uncommon and represents between 1% and 3% of all malignant renal tumors.
  • Primary rhabdomyosarcoma of the kidney in adult age is unusual, and only sporadic cases have been reported.
  • We report a new case of pleomorphic rhabdomyosarcoma of the kidney in an adult patient.
  • [MeSH-major] Kidney Neoplasms / pathology. Rhabdomyosarcoma / pathology
  • [MeSH-minor] Adult. Female. Humans. Immunohistochemistry

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18621001.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


20. Deniz PP, Kalac N, Ucoluk GO, Samurkasoglu B, Tastepe AI, Gulhan E, Demirag F: A rare tumor of the diaphragm: pleomorphic rhabdomyosarcoma. Ann Thorac Surg; 2008 May;85(5):1802-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A rare tumor of the diaphragm: pleomorphic rhabdomyosarcoma.
  • Pathologic examination of the biopsy specimen revealed pleomorphic rhabdomyosarcoma.
  • [MeSH-major] Diaphragm. Muscle Neoplasms / diagnosis. Rhabdomyosarcoma / diagnosis
  • [MeSH-minor] Actins / analysis. Biomarkers, Tumor / analysis. Biopsy. Cough / etiology. Desmin / analysis. Diagnosis, Differential. Dyspnea / etiology. Fatigue / etiology. Female. Humans. Lung / pathology. Lung Neoplasms / diagnosis. Lung Neoplasms / pathology. Lung Neoplasms / secondary. Lung Neoplasms / surgery. Middle Aged. Pneumonectomy. Tomography, X-Ray Computed

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18442596.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Actins; 0 / Biomarkers, Tumor; 0 / Desmin
  •  go-up   go-down


21. Fountas KN, Donner RS, Nikolakakos LG, Feltes CH, Karampelas I, Robinson JS Jr: Adult paravertebral pleomorphic rhabdomyosarcoma infiltrating diffusely the whole spinal axis. Case report. J Neurosurg Spine; 2005 Mar;2(3):344-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adult paravertebral pleomorphic rhabdomyosarcoma infiltrating diffusely the whole spinal axis. Case report.
  • The authors report a unique case of diffuse spinal metastatic disease due to a pleomorphic rhabdomyosarcoma (RMS) in an adult.
  • [MeSH-major] Rhabdomyosarcoma / pathology. Spinal Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. Middle Aged

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15796361.001).
  • [ISSN] 1547-5654
  • [Journal-full-title] Journal of neurosurgery. Spine
  • [ISO-abbreviation] J Neurosurg Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


22. Li G, Ogose A, Kawashima H, Umezu H, Hotta T, Tohyama T, Ariizumi T, Endo N: Cytogenetic and real-time quantitative reverse-transcriptase polymerase chain reaction analyses in pleomorphic rhabdomyosarcoma. Cancer Genet Cytogenet; 2009 Jul;192(1):1-9
MedlinePlus Health Information. consumer health - Bone Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytogenetic and real-time quantitative reverse-transcriptase polymerase chain reaction analyses in pleomorphic rhabdomyosarcoma.
  • Pleomorphic rhabdomyosarcoma (PRMS) is a rare variant of rhabdomyosarcoma that occurs mostly in adults.
  • We herein report a cytogenetic study of three cases of pleomorphic rhabdomyosarcoma using a conventional G-banded karyotyping analysis.
  • No obviously consistent structural alterations can be found in these 10 PRMS cases, however, thereby suggesting that it is difficult to confirm whether these complex karyotypes correlated with the diagnosis or clinical outcome in PRMS.
  • In this study, we detected MyoD1 and myogenin gene transcripts at the mRNA level in four cases of PRMS together with other soft-tissue sarcomas, including seven cases of malignant fibrous hitiocytoma, five cases of liposacroma, and three cases of leiomyosacroma using a real-time quantitative reverse-transcriptase polymerase chain reaction (RT-PCR) analysis.
  • Our findings suggest that the detections of MyoD1 and myogenin transcripts using real-time quantitative RT-PCR, combined with immunohistochemical stains, are extremely sensitive and useful for the diagnosis of PRMS.
  • [MeSH-major] Abdominal Neoplasms / diagnosis. Bone Neoplasms / diagnosis. Cytogenetic Analysis / methods. Reverse Transcriptase Polymerase Chain Reaction / methods. Rhabdomyosarcoma / diagnosis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Retrospective Studies

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19480930.001).
  • [ISSN] 1873-4456
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Case Reports; Evaluation Studies; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


23. Chmaj-Wierzchowska K, Wierzchowski M, Szymanowski K, Czerniak T, Mróz M, Sobiak S, Opala T: Pleomorphic rhabdomyosarcoma of the uterine corpus--a case report. Ginekol Pol; 2010 Jul;81(7):541-3
MedlinePlus Health Information. consumer health - Uterine Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pleomorphic rhabdomyosarcoma of the uterine corpus--a case report.
  • Pleomorphic rhabdomyosarcoma of the uterus is a rare malignant tumor.
  • The patient underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy with postoperative chemotherapy due to pleomorphic rhabdomyosarcoma of the uterus.
  • The case of rhabdomyosarcoma, together with the review of the literature, is presented in the following work.
  • [MeSH-major] Postmenopause. Rhabdomyosarcoma / diagnosis. Rhabdomyosarcoma / therapy. Uterine Neoplasms / diagnosis. Uterine Neoplasms / therapy

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20825058.001).
  • [ISSN] 0017-0011
  • [Journal-full-title] Ginekologia polska
  • [ISO-abbreviation] Ginekol. Pol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
  •  go-up   go-down


24. Kourda N, El Atat R, Derouiche A, Bettaib I, Baltagi S, Zermani R: [Paratesticular pleomorphic rhabdomyosarcoma in an adult: diagnosis and management]. Cancer Radiother; 2007 Sep;11(5):280-3
MedlinePlus Health Information. consumer health - Testicular Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Paratesticular pleomorphic rhabdomyosarcoma in an adult: diagnosis and management].
  • A paratesticular pleomorphic rhabdomyosarcoma occurring in a 63-year old man is reported.
  • CT-scan and histological examination with immunohistochemical study were necessary for the diagnosis and stadification of this cancer.
  • [MeSH-major] Rhabdomyosarcoma. Testicular Neoplasms

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17611140.001).
  • [ISSN] 1278-3218
  • [Journal-full-title] Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
  • [ISO-abbreviation] Cancer Radiother
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  •  go-up   go-down


25. Eyden B: Pleomorphic rhabdomyosarcoma showing smooth-muscle and fibrohistiocytic differentiation: a single case report. Ultrastruct Pathol; 2010 Feb;34(1):42-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pleomorphic rhabdomyosarcoma showing smooth-muscle and fibrohistiocytic differentiation: a single case report.
  • Rhabdomyosarcoma has traditionally been subclassified into alveolar, embryonal, and pleomorphic variants.
  • The author recently encountered a myogenic sarcoma, with all the common markers of rhabdomyosarcoma, but expressing the unusual features of alpha-smooth-muscle actin and abundant rough endoplasmic reticulum (rER).
  • Subplasmalemmal smooth-muscle-type myofilaments with focal densities and rare sarcomeric filaments were seen.
  • Given the four lines of differentiation--striated muscle, smooth muscle, fibroblastic, and histiocytic--a name reflecting its phenotype would be pleomorphic rhabdomyosarcoma showing smooth-muscle and fibrohistiocytic differentiation.
  • [MeSH-major] Fibroblasts / ultrastructure. Histiocytes / ultrastructure. Muscle, Smooth / ultrastructure. Rhabdomyosarcoma / pathology. Soft Tissue Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20070153.001).
  • [ISSN] 1521-0758
  • [Journal-full-title] Ultrastructural pathology
  • [ISO-abbreviation] Ultrastruct Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / ACTA2 protein, human; 0 / Actins; 0 / Biomarkers, Tumor
  •  go-up   go-down


26. Prgomet D, Males J, Manojlović S, Bumber Z: [Pleomorphic rhabdomyosarcoma of the larynx--a case report and literature review]. Acta Med Croatica; 2006 Jun;60(3):255-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pleomorphic rhabdomyosarcoma of the larynx--a case report and literature review].
  • Rhabdomyosarcoma is a very rare malignant tumor of the larynx which can present in a number of histologic variants.
  • The pleomorphic variant of the tumor has been described in 16 patients to date.
  • Being a rarity, rhabdomyosarcoma is as a rule managed according to the principle of treatment for malignant mesenchymal tumors of the head and neck, and includes radical surgery with postoperative radiotherapy and/or chemotherapy.
  • A case is presented of a pleomorphic rhabdomyosarcoma of the vocal cord.
  • [MeSH-major] Laryngeal Neoplasms. Rhabdomyosarcoma

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16933839.001).
  • [ISSN] 1330-0164
  • [Journal-full-title] Acta medica Croatica : c̆asopis Hravatske akademije medicinskih znanosti
  • [ISO-abbreviation] Acta Med Croatica
  • [Language] hrv
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Croatia
  •  go-up   go-down


27. Spugnini EP, Filipponi M, Romani L, Dotsinsky I, Mudrov N, Citro G, Baldi A: Electrochemotherapy treatment for bilateral pleomorphic rhabdomyosarcoma in a cat. J Small Anim Pract; 2010 Jun;51(6):330-2
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Electrochemotherapy treatment for bilateral pleomorphic rhabdomyosarcoma in a cat.
  • The cat had conservative surgical excision in order to preserve the eyelids' functionality; however, the histopathological report came with a diagnosis of incompletely excised bilateral pleomorphic rhabdomyosarcoma.
  • [MeSH-major] Cat Diseases / drug therapy. Electrochemotherapy / veterinary. Eyelid Neoplasms / veterinary. Rhabdomyosarcoma / veterinary

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20492454.001).
  • [ISSN] 1748-5827
  • [Journal-full-title] The Journal of small animal practice
  • [ISO-abbreviation] J Small Anim Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  •  go-up   go-down


28. Fadare O, Bonvicino A, Martel M, Renshaw IL, Azodi M, Parkash V: Pleomorphic rhabdomyosarcoma of the uterine corpus: a clinicopathologic study of 4 cases and a review of the literature. Int J Gynecol Pathol; 2010 Mar;29(2):122-34
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pleomorphic rhabdomyosarcoma of the uterine corpus: a clinicopathologic study of 4 cases and a review of the literature.
  • We report the clinicopathologic features of 4 cases of pure pleomorphic rhabdomyosarcoma of the uterine corpus with an emphasis on their frequent expression of CD10 and CD56, review the relevant literature, and discuss differential diagnostic considerations.
  • In addition to the expected findings, other notable morphologic features included tumor giant cells (4/4), osteoclast-like giant cells (1/4), patchy myxoid stroma (4/4), and only infrequent cytoplasmic cross striations (1/4).
  • These data indicate that pleomorphic rhabdomyosarcoma of the uterine corpus is a highly aggressive, rapidly progressive tumor with a high case-fatality rate.
  • [MeSH-major] Rhabdomyosarcoma / pathology. Uterine Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Uterine Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20173498.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


29. Doyle B, Morton JP, Delaney DW, Ridgway RA, Wilkins JA, Sansom OJ: p53 mutation and loss have different effects on tumourigenesis in a novel mouse model of pleomorphic rhabdomyosarcoma. J Pathol; 2010 Oct;222(2):129-37
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] p53 mutation and loss have different effects on tumourigenesis in a novel mouse model of pleomorphic rhabdomyosarcoma.
  • Pleomorphic rhabdomyosarcoma is the most common variant of this tumour in adults and has a very poor outcome.
  • Two genes which are known to play a role in rhabdomyosarcoma development are KRas and p53.
  • It is now hypothesized that these mutant forms of p53 may be playing an oncogenic role, over and above simple loss of the wild-type function.
  • In this study, we use Cre-LoxP technology to develop a novel mouse model of rhabdomyosarcoma, crossing mice expressing a common KRas mutation (G12V) with mice that either lose p53 expression or express a mutant form of p53.
  • We found that either complete loss of p53 (p53(fl/fl)) or the expression of one mutant p53 allele with concomitant loss of the second allele (p53(R172H/+)) resulted in the rapid development of rhabdomyosarcoma in 15/16 and 19/19 mice, respectively.
  • Fourteen out of 16 p53(R172H/) mice developed rhabdomyosarcoma, compared with two out of 31 p53(fl/+) mice.
  • [MeSH-major] Genes, p53 / genetics. Point Mutation. Rhabdomyosarcoma / genetics. Soft Tissue Neoplasms / genetics

  • KOMP Repository. gene/protein/disease-specific - KOMP Repository (subscription/membership/fee required).
  • Mouse Genome Informatics (MGI). Mouse Genome Informatics (MGI) .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2010 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
  • [CommentIn] J Pathol. 2010 Oct;222(2):124-8 [20821751.001]
  • (PMID = 20662002.001).
  • [ISSN] 1096-9896
  • [Journal-full-title] The Journal of pathology
  • [ISO-abbreviation] J. Pathol.
  • [Language] eng
  • [Grant] United Kingdom / Cancer Research UK / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Tumor Suppressor Protein p53; EC 3.6.5.2 / Kras2 protein, mouse; EC 3.6.5.2 / Proto-Oncogene Proteins p21(ras)
  •  go-up   go-down


30. Yeasmin S, Nakayama K, Oride A, Ishibashi M, Ishikawa N, Katagiri A, Iida K, Nakayama N, Miyazaki K: A case of extremely chemoresistant pure pleomorphic rhabdomyosarcoma of the uterus associated with a high serum LDH level. Eur J Gynaecol Oncol; 2008;29(5):518-22
MedlinePlus Health Information. consumer health - Uterine Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of extremely chemoresistant pure pleomorphic rhabdomyosarcoma of the uterus associated with a high serum LDH level.
  • BACKGROUND: Pleomorphic rhabdomyosarcoma (RMS) of gynecologic origin is an exceedingly rare, highly malignant tumor.
  • Ultimately, she was diagnosed with pleomorphic RMS.
  • Ultimately she died within 20 months of the diagnosis.
  • CONCLUSION: It is important to have better insight and to set a standard multimodal treatment for adult RMS.
  • [MeSH-major] L-Lactate Dehydrogenase / blood. Rhabdomyosarcoma / pathology. Uterine Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19051826.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] EC 1.1.1.27 / L-Lactate Dehydrogenase
  •  go-up   go-down


31. Kishore B, Khare P, Gupta RJ, Gupta C, Khare V: A rare case of paratesticular pleomorphic rhabdomyosarcoma diagnosed by fine needle aspiration: a case report. Diagn Cytopathol; 2010 Feb;38(2):121-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A rare case of paratesticular pleomorphic rhabdomyosarcoma diagnosed by fine needle aspiration: a case report.
  • Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of children and young adults.
  • It represents 6.5% of all malignant tumors in pediatrics with an annual incidence of 4 to 7 cases per million children.
  • Embryonal RMS arising in paratesticular region in young males is a common entity, however pleomorphic RMS in such location is quite rare.
  • Fine needle aspiration showed cellular smears comprising of pleomorphic population of mostly singly scattered cells and few cell aggregates.
  • A diagnosis of paratesticular malignant mesenchymal tumor probably RMS was made.
  • On histopathology, it was reported as pleomorphic RMS.
  • The case is being presented because of diagnosis of RMS on Fine needle aspiration and rare occurrence of pleomorphic RMS in paratesticular location.
  • [MeSH-major] Rhabdomyosarcoma / diagnosis. Scrotum / pathology. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Biopsy, Fine-Needle. Humans. Lymphatic Metastasis / diagnosis. Male

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19790247.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


32. Mehra S, de la Roza G, Tull J, Shrimpton A, Valente A, Zhang S: Detection of FOXO1 (FKHR) gene break-apart by fluorescence in situ hybridization in formalin-fixed, paraffin-embedded alveolar rhabdomyosarcomas and its clinicopathologic correlation. Diagn Mol Pathol; 2008 Mar;17(1):14-20
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In this study, we used FOXO1 (FKHR) gene break-apart FISH probe, which can detect both of the translocations involving the FOXO1 gene, and tested 20 cases of rhabdomyosarcoma (RMS) including 6 cases of ARMS, 8 ERMS, 1 pleomorphic type, 5 not otherwise specified (RMS-NOS), and 10 non-RMS sarcomas.
  • Four pathologists independently reviewed all RMS and a consensus diagnosis was also reached in discrepant cases.
  • As characteristic genetic alterations of ARMS can be identified in 40% of RMS-NOS cases in our study, the FISH assay would provide an additional useful tool in the diagnosis and prognosis of ARMS, and an alternative to RT-PCR.
  • [MeSH-major] Chromosome Breakage. Forkhead Transcription Factors / genetics. Formaldehyde / pharmacology. In Situ Hybridization, Fluorescence. Muscle Neoplasms / diagnosis. Muscle Neoplasms / genetics. Paraffin Embedding. Rhabdomyosarcoma, Alveolar / diagnosis. Rhabdomyosarcoma, Alveolar / genetics
  • [MeSH-minor] Adolescent. Adult. Base Sequence. Child. Child, Preschool. Chromosomes, Human, Pair 1. Chromosomes, Human, Pair 13. Chromosomes, Human, Pair 2. Female. Humans. Infant. Male. Middle Aged. Molecular Sequence Data. Oncogene Proteins, Fusion / genetics. Prognosis. Translocation, Genetic. Tumor Cells, Cultured

  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. FORMALDEHYDE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18303411.001).
  • [ISSN] 1052-9551
  • [Journal-full-title] Diagnostic molecular pathology : the American journal of surgical pathology, part B
  • [ISO-abbreviation] Diagn. Mol. Pathol.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / FOXO1 protein, human; 0 / Forkhead Transcription Factors; 0 / Oncogene Proteins, Fusion; 1HG84L3525 / Formaldehyde
  •  go-up   go-down


33. Watanabe Y, Ishizu A, Kataoka T, Nakai H, Sato T, Hoshiai H: Touch preparation of primary uterine pleomorphic rhabdomyosarcoma: report of a case with clinical cytopathologic features. Acta Cytol; 2010 Sep-Oct;54(5 Suppl):1027-30
MedlinePlus Health Information. consumer health - Uterine Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Touch preparation of primary uterine pleomorphic rhabdomyosarcoma: report of a case with clinical cytopathologic features.
  • BACKGROUND: Primary pure uterine rhabdomyosarcoma (RMS) is an extremely rare tumor, and no cytopathologic characteristics of this tumor have been reported before.
  • CASE: We report the clinicopathologic characteristics, including the cytopathologic findings of touch preparations, of a pleomorphic RMS in a postmenopausal woman.
  • [MeSH-major] Cytological Techniques / methods. Rhabdomyosarcoma / pathology. Uterine Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21053592.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


34. Haroun SA, Elnaiem EA, Zaki ZM, Adam I: Aggressive rhabdomyosarcoma of the vulva in a young Sudanese woman. Saudi Med J; 2007 Mar;28(3):461-2
MedlinePlus Health Information. consumer health - Vulvar Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Aggressive rhabdomyosarcoma of the vulva in a young Sudanese woman.
  • Pathological evaluation revealed pleomorphic rhabdomyosarcoma.
  • [MeSH-major] Neoplasm Invasiveness / pathology. Rhabdomyosarcoma / pathology. Vulvar Neoplasms / pathology
  • [MeSH-minor] Adult. Biopsy, Needle. Disease Progression. Fatal Outcome. Female. Humans. Immunohistochemistry. Neoplasm Staging. Sudan. Terminally Ill

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17334481.001).
  • [ISSN] 0379-5284
  • [Journal-full-title] Saudi medical journal
  • [ISO-abbreviation] Saudi Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Saudi Arabia
  •  go-up   go-down


35. Semino A, Danova M, Perlini S, Palladini G, Riccardi A, Perfetti V: Unusual manifestations of disseminated neoplasia at presentation: right-sided heart failure due to a massive cardiac metastasis and autoimmune thrombocytopenia in pleomorphic rhabdomyosarcoma of the adult. Am J Clin Oncol; 2006 Feb;29(1):102-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unusual manifestations of disseminated neoplasia at presentation: right-sided heart failure due to a massive cardiac metastasis and autoimmune thrombocytopenia in pleomorphic rhabdomyosarcoma of the adult.
  • This report describes the occurrence of a massive cardiac metastasis at diagnosis of leg rhabdomyosarcoma in a middle-age adult.
  • [MeSH-major] Heart Neoplasms / secondary. Rhabdomyosarcoma / secondary. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adult. Comorbidity. Fatal Outcome. Heart Failure / etiology. Humans. Leg / pathology. Male. Purpura, Thrombocytopenic, Idiopathic / drug therapy

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16462513.001).
  • [ISSN] 1537-453X
  • [Journal-full-title] American journal of clinical oncology
  • [ISO-abbreviation] Am. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


36. Hartmann JT, Patel S: Recent developments in salvage chemotherapy for patients with metastatic soft tissue sarcoma. Drugs; 2005;65(2):167-78
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The number of effective cytotoxic agents for the treatment of patients with metastatic adult soft tissue sarcoma is limited, especially when patients have failed anthracycline- and ifosfamide-based chemotherapy.
  • Small round cell tumours (SRCTs), such as Ewing's sarcoma/primitive neuroectodermal tumour, desmoplastic SRCT and rhabdomyosarcoma, are chemotherapy-sensitive and potentially curable malignancies, which are treated with multimodality, dose-intensive, neoadjuvant protocols regardless of size or overt metastatic disease.
  • Most other high-grade (grading >I), so-called 'adult type', soft tissue sarcomas such as fibrosarcoma, liposarcoma, pleomorphic and synovial sarcomas are treated with an anthracycline-based regimen with or without ifosfamide as front-line therapy.
  • In relapsed 'adult type' soft tissue sarcomas, trofosfamide, gemcitabine and trabectedin (ecteinascidin 743) appear to be drugs associated with some activity and an acceptable toxicity profile.


37. Lüdike A, Knolle J, Schön R, Hinze P, Hofmann HS, Schreiber J: [Primary pulmonary rhabdomyosarcoma as a rare differential diagnosis of small cell lung cancer]. Pneumologie; 2005 Jul;59(7):456-60
MedlinePlus Health Information. consumer health - Lung Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary pulmonary rhabdomyosarcoma as a rare differential diagnosis of small cell lung cancer].
  • Primary pulmonary rhabdomyosarcoma is a rare entity and the histological differential diagnosis can be difficult.
  • Bronchial biopsies again showed a small cell tumor, although immunohistochemistry proved it to be a pleomorphic rhabdomyosarcoma.
  • The patient died from metastatic primary rhabdomyosarcoma of the lung.
  • Appraisal of the atypical clinical course and a close dialogue between pathologists and clinicians enabled the correct diagnosis.
  • [MeSH-major] Carcinoma, Small Cell / pathology. Lung Neoplasms / pathology. Rhabdomyosarcoma / pathology
  • [MeSH-minor] Adult. Combined Modality Therapy. Diagnosis, Differential. Fatal Outcome. Female. Humans. Recurrence

  • Genetic Alliance. consumer health - Lung Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16047279.001).
  • [ISSN] 0934-8387
  • [Journal-full-title] Pneumologie (Stuttgart, Germany)
  • [ISO-abbreviation] Pneumologie
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


38. Scott RS, Jagirdar J: Right atrial botryoid rhabdomyosarcoma in an adult patient with recurrent pleomorphic rhabdomyosarcomas following doxorubicin therapy. Ann Diagn Pathol; 2007 Aug;11(4):274-6
Hazardous Substances Data Bank. DOXORUBICIN .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Right atrial botryoid rhabdomyosarcoma in an adult patient with recurrent pleomorphic rhabdomyosarcomas following doxorubicin therapy.
  • We describe a case of a 37-year-old Hispanic woman who presented with a right atrial botryoid rhabdomyosarcoma 2 years after doxorubicin therapy for a recurrent pleomorphic rhabdomyosarcoma of the chest wall.
  • [MeSH-major] Antibiotics, Antineoplastic / therapeutic use. Doxorubicin / therapeutic use. Heart Atria / pathology. Heart Neoplasms / pathology. Rhabdomyosarcoma, Embryonal / pathology
  • [MeSH-minor] Adult. Chemotherapy, Adjuvant. Disease-Free Survival. Female. Humans. Magnetic Resonance Imaging. Neoplasm Recurrence, Local. Thorax / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17630111.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 80168379AG / Doxorubicin
  •  go-up   go-down


39. Batoroev YK, Nguyen GK: Esophageal rhabdomyosarcoma: report of a case diagnosed by imprint cytology. Acta Cytol; 2006 Mar-Apr;50(2):213-6
MedlinePlus Health Information. consumer health - Esophageal Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Esophageal rhabdomyosarcoma: report of a case diagnosed by imprint cytology.
  • BACKGROUND: Primary esophageal rhabdomyosarcoma (PER) is a very rare neoplasm with only 15 cases reported in the literature.
  • We report a case of PER with diagnosis by imprint cytology.
  • The smears revealed abundant, pleomorphic, malignant cells with basophilic cytoplasm.
  • Some spindle-shaped cancer cells showed intracytoplasmic cross-striations, indicating a pleomorphic rhabdomyosarcoma, as confirmed by histologic and immunohistochemical studies of the biopsied tumor tissue and resected tumor.
  • CONCLUSION: The presence of pleomorphic malignant cells with intracytoplasmic cross striations is a characteristic feature of pleomorphic rhabdomyosarcoma.
  • [MeSH-major] Esophageal Neoplasms / diagnosis. Esophageal Neoplasms / pathology. Rhabdomyosarcoma / diagnosis. Rhabdomyosarcoma / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16610693.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


40. Guillou L, Aurias A: Soft tissue sarcomas with complex genomic profiles. Virchows Arch; 2010 Feb;456(2):201-17
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Soft tissue sarcomas (STS) with complex genomic profiles (50% of all STS) are predominantly composed of spindle cell/pleomorphic sarcomas, including leiomyosarcoma, myxofibrosarcoma, pleomorphic liposarcoma, pleomorphic rhabdomyosarcoma, malignant peripheral nerve sheath tumor, angiosarcoma, extraskeletal osteosarcoma, and spindle cell/pleomorphic unclassified sarcoma (previously called spindle cell/pleomorphic malignant fibrous histiocytoma).

  • MedlinePlus Health Information. consumer health - Soft Tissue Sarcoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20217954.001).
  • [ISSN] 1432-2307
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / DNA, Neoplasm
  • [Number-of-references] 109
  •  go-up   go-down


41. Hasegawa T: [Molecular pathological diagnosis of soft tissue tumors]. Rinsho Byori; 2010 Apr;58(4):371-81

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Molecular pathological diagnosis of soft tissue tumors].
  • Among soft tissue tumors, which have some difficulties in diagnosis and treatment, it is known that distinctive chromosomal and gene abnormalities such as chromosomal translocations and fusion genes resulting from these translocations can be detected.
  • We have focused on the research and development of split-signal DNA probes for FISH analysis, which can establish an accurate diagnosis by detecting the specific fusion genes for soft tissue tumors.
  • Using these probes as well as commercially available probes, we conduct the FISH analysis on formalin-fixed, paraffin-embedded histological specimens to apply these methods to the routine pathological diagnosis.
  • In this article, we introduce (1) principle of detecting fusion genes by RT-PCR and FISH, (2) outlines of FISH using split-signal probes, and (3) results of FISH analysis in Ewing sarcoma/PNET, rhabdomyosarcoma, pleomorphic liposarcoma and extraskeletal myxoid chondrosarcoma.
  • [MeSH-major] In Situ Hybridization, Fluorescence. Reverse Transcriptase Polymerase Chain Reaction. Soft Tissue Neoplasms / diagnosis. Soft Tissue Neoplasms / genetics
  • [MeSH-minor] DNA Probes. Gene Fusion. Humans. Liposarcoma / diagnosis. Liposarcoma / genetics. Rhabdomyosarcoma / diagnosis. Rhabdomyosarcoma / genetics. Sarcoma, Ewing / diagnosis. Sarcoma, Ewing / genetics. Translocation, Genetic

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20496765.001).
  • [ISSN] 0047-1860
  • [Journal-full-title] Rinsho byori. The Japanese journal of clinical pathology
  • [ISO-abbreviation] Rinsho Byori
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / DNA Probes
  • [Number-of-references] 6
  •  go-up   go-down


42. Doladzas T, Arvelakis A, Karavokyros IG, Gougoudi E, Pikoulis E, Patsouris E, Michail PO: Primary rhabdomyosarcoma of the lung arising over cystic pulmonary adenomatoid malformation. Pediatr Hematol Oncol; 2005 Sep;22(6):525-9
MedlinePlus Health Information. consumer health - Lung Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary rhabdomyosarcoma of the lung arising over cystic pulmonary adenomatoid malformation.
  • The authors report the case of a 2-year-old girl with pulmonary cystic adenomatoid malformation type II who presented with a mass on the lower lobe of the left lung.
  • Resection and histological examination revealed pleomorphic rhabdomyosarcoma.
  • The literature on primary rhabdomyosarcoma of the lung in children is reviewed.
  • [MeSH-major] Cystic Adenomatoid Malformation of Lung, Congenital / therapy. Lung Neoplasms / therapy. Rhabdomyosarcoma / therapy

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16169819.001).
  • [ISSN] 0888-0018
  • [Journal-full-title] Pediatric hematology and oncology
  • [ISO-abbreviation] Pediatr Hematol Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  •  go-up   go-down


43. Post SM, Lozano G: You can win by losing: p53 mutations in rhabdomyosarcomas. J Pathol; 2010 Oct;222(2):124-8
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Unlike rhabdomyosarcomas observed in paediatric patients which typically respond well to chemotherapeutic treatment, adults generally present with pleomorphic rhabdomyosarcomas that are typically associated with poor prognosis.
  • Therefore, understanding the molecular biology that gives rise to pleomorphic rhabdomyosarcomas is critical.
  • In this issue of The Journal of Pathology, Doyle and colleagues have generated elegant tissue-specific Cre/loxP-dependent mouse models that mimic pleomorphic rhabdomyosarcoma development in humans.
  • Mice that express mutant p53 have decreased survival with development of aggressive metastases as compared to mice that have simply lost wild-type p53.
  • [MeSH-major] Genes, p53 / genetics. Mutation. Rhabdomyosarcoma / genetics. Soft Tissue Neoplasms / genetics

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2010 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
  • [CommentOn] J Pathol. 2010 Oct;222(2):129-37 [20662002.001]
  • (PMID = 20821751.001).
  • [ISSN] 1096-9896
  • [Journal-full-title] The Journal of pathology
  • [ISO-abbreviation] J. Pathol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA016672
  • [Publication-type] Comment; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Tumor Suppressor Protein p53
  •  go-up   go-down


44. Benesch M, Windelberg M, Sauseng W, Witt V, Fleischhack G, Lackner H, Gadner H, Bode U, Urban C: Compassionate use of bevacizumab (Avastin) in children and young adults with refractory or recurrent solid tumors. Ann Oncol; 2008 Apr;19(4):807-13
MedlinePlus Health Information. consumer health - Cancer in Children.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PATIENTS AND METHODS: Fifteen patients (male: n = 8; female: n = 7; median age, 14.6 years) received bevacizumab for recurrent or progressive solid tumors (carcinoma: n = 3; neuroblastoma: n = 2; astrocytoma grade III: n = 2; rhabdomyosarcoma: n = 2; nephroblastoma: n = 2; benign vascular tumors: n = 2; synovial sarcoma: n = 1; and malignant hemangiopericytoma: n = 1) on a compassionate basis.
  • Radiographic objective responses (partial responses) were observed in two patients with astrocytoma grade III and in one patient each with neuroblastoma and pleomorphic rhabdomyosarcoma, respectively.

  • MedlinePlus Health Information. consumer health - Cancer Chemotherapy.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18056650.001).
  • [ISSN] 1569-8041
  • [Journal-full-title] Annals of oncology : official journal of the European Society for Medical Oncology
  • [ISO-abbreviation] Ann. Oncol.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Angiogenesis Inhibitors; 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 2S9ZZM9Q9V / Bevacizumab
  •  go-up   go-down


45. Bisby TM, Pratt SM, Kent Fenton R, Nickie Baird A, Thompson CA, Lin TL: What is your diagnosis? Perifemoral mass in a cow. Vet Clin Pathol; 2009 Sep;38(3):343-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] What is your diagnosis? Perifemoral mass in a cow.
  • Impression smears made from an excisional biopsy contained a population of pleomorphic mesenchymal cells with abundant, periodic acid-Schiff-positive (PAS), intracytoplasmic granular material, and rare elongated multinucleated cells consistent with strap-like cells.
  • A cytologic diagnosis of sarcoma was made, with rhabdomyosarcoma considered most likely based on the large amount of PAS-positive material (presumed to be glycogen) and the rare strap-like cells.
  • Histopathologic sections contained an unencapsulated, densely cellular neoplasm composed of haphazardly arranged highly pleomorphic mesenchymal cells and a few small round cells.
  • A diagnosis of pleomorphic rhabdomyosarcoma was made.
  • While cytologic findings may suggest rhabdomyosarcoma, cytologic features can be highly variable, and a definitive diagnosis usually requires cytochemical and immunohistochemical staining.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19490567.001).
  • [ISSN] 0275-6382
  • [Journal-full-title] Veterinary clinical pathology
  • [ISO-abbreviation] Vet Clin Pathol
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


46. Shimamoto K, Tanji N, Ozaw A, Sasaki T, Ikeda T, Iseda T, Yokoyama M: [Intrascrotal rhabdomyosarcoma in adult: a case report]. Nihon Hinyokika Gakkai Zasshi; 2009 May;100(4):545-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Intrascrotal rhabdomyosarcoma in adult: a case report].
  • With a diagnosis of right intrascrotal tumor, the patient underwent right high orchiectomy.
  • The pathological diagnosis of pleomorphic rhabdomyosarcoma arisen from the right spermatic cord was made.
  • Systemic chemotherapy with vincristine, actinomycin D, plus cyclophosphamide (VAC therapy), and etoposide plus cisplatin (EP therapy) were made according to Intergroup Rhabdomyosarcoma Study (IRS)-IV Regimen 45.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Chemotherapy, Adjuvant. Genital Neoplasms, Male / therapy. Lymph Node Excision. Orchiectomy. Radiotherapy, Adjuvant. Rhabdomyosarcoma / therapy. Scrotum

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19514277.001).
  • [ISSN] 0021-5287
  • [Journal-full-title] Nihon Hinyōkika Gakkai zasshi. The japanese journal of urology
  • [ISO-abbreviation] Nippon Hinyokika Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


47. Rizvi SA, Gupta Y, Gupta M: Surgical treatment and histopathological analysis of proptosis. Nepal J Ophthalmol; 2010 Jan-Jun;2(1):31-4
MedlinePlus Health Information. consumer health - Eye Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • According to location and type of tumour, different surgical options like anterior orbitotomy, lateral orbitotomy and medial orbitotomy were considered.
  • Three cases of rhabdomyosarcoma, 3 cases of dermoid cyst and 1 case each of optic nerve glioma were found in pediatric age group.
  • The most common benign adult tumor found in our study was pleomorphic adenoma of the lacrimal gland {3 (20%)}.
  • Early diagnosis and timely surgical intervention provide good functional and cosmetic results.
  • [MeSH-minor] Adolescent. Adult. Aged. Biopsy. Child. Child, Preschool. Diagnosis, Differential. Humans. Infant. Infant, Newborn. Middle Aged. Retrospective Studies. Treatment Outcome. Young Adult

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21141324.001).
  • [ISSN] 2072-6805
  • [Journal-full-title] Nepalese journal of ophthalmology : a biannual peer-reviewed academic journal of the Nepal Ophthalmic Society : NEPJOPH
  • [ISO-abbreviation] Nepal J Ophthalmol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Nepal
  •  go-up   go-down


48. Inoue K, Yoshida M, Takahashi M, Cho YM, Takami S, Nishikawa A: Rhabdomyosarcoma in the abdominal cavity of a 12-month-old female donryu rat. J Toxicol Pathol; 2009 Sep;22(3):195-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rhabdomyosarcoma in the abdominal cavity of a 12-month-old female donryu rat.
  • Recently, we experienced a case of rhabdomyosarcoma as a white mass involving the junction of the esophagus and stomach in the abdominal cavity of a 12-month-old female Donryu rat.
  • Although the neoplastic cells varied in appearance, pleomorphic atypical cells with abundant eosinophilic cytoplasm were prominent.
  • Taken together these findings, this tumor was diagnosed as a pleomorphic rhabdomyosarcoma, probably derived from the muscle layer of the lower part of the esophagus.
  • This is the first report of rhabdomyosarcoma in a Donryu rat.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 22271994.001).
  • [ISSN] 0914-9198
  • [Journal-full-title] Journal of toxicologic pathology
  • [ISO-abbreviation] J Toxicol Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Other-IDs] NLM/ PMC3252041
  • [Keywords] NOTNLM ; esophagus / rat / rhabdomyosarcoma
  •  go-up   go-down


49. Chang SC, Inui K, Lee WC, Hsuan SL, Chien MS, Chen CH, Chang SJ, Liao JW: Spontaneous rhabdomyosarcoma in a young Sprague-Dawley rat. Toxicol Pathol; 2008 Oct;36(6):866-70
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spontaneous rhabdomyosarcoma in a young Sprague-Dawley rat.
  • Based on the pathology results, a spontaneous rhabdomyosarcoma with pleomorphic type was diagnosed in a young SD rat.
  • [MeSH-major] Head and Neck Neoplasms / veterinary. Rats, Sprague-Dawley. Rhabdomyosarcoma / veterinary. Rodent Diseases / pathology. Thoracic Neoplasms / veterinary
  • [MeSH-minor] Actins / analysis. Acute Disease. Animals. Diagnosis, Differential. Hematoxylin. Histocytochemistry. Immunohistochemistry. Male. Periodic Acid-Schiff Reaction. Phosphotungstic Acid. Proliferating Cell Nuclear Antigen / analysis. Rats. Staining and Labeling

  • MedlinePlus Health Information. consumer health - Head and Neck Cancer.
  • Hazardous Substances Data Bank. HEMATOXYLIN .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18776162.001).
  • [ISSN] 1533-1601
  • [Journal-full-title] Toxicologic pathology
  • [ISO-abbreviation] Toxicol Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Proliferating Cell Nuclear Antigen; 0 / smooth muscle actin, rat; 12067-99-1 / Phosphotungstic Acid; YKM8PY2Z55 / Hematoxylin
  •  go-up   go-down


50. Nascimento AF, Bertoni F, Fletcher CD: Epithelioid variant of myxofibrosarcoma: expanding the clinicomorphologic spectrum of myxofibrosarcoma in a series of 17 cases. Am J Surg Pathol; 2007 Jan;31(1):99-105
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Differential diagnosis included carcinoma, melanoma, myoepithelial carcinoma, pleomorphic liposarcoma, and pleomorphic rhabdomyosarcoma.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / analysis. Carcinoma / diagnosis. Combined Modality Therapy. Diagnosis, Differential. Extremities. Fatal Outcome. Female. Humans. Immunoenzyme Techniques. Liposarcoma / diagnosis. Male. Melanoma / diagnosis. Middle Aged. Myoepithelioma / diagnosis. Rhabdomyosarcoma / diagnosis

  • MedlinePlus Health Information. consumer health - Soft Tissue Sarcoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17197925.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down


51. Kordek R, Sowa P, Panasiuk M, Kmieciak M, Chudobinski C, Pluciennik E, Bednarek AK, Potemski P, Jesionek-Kupnicka D: Primary osseous rhabdomyosarcoma with focal matrix formation mimicking osteosarcoma. Pathol Res Pract; 2007;203(12):873-7
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary osseous rhabdomyosarcoma with focal matrix formation mimicking osteosarcoma.
  • We present an unusual case of primary osseous pleomorphic rhabdomyosarcoma with focal matrix formation mimicking osteosarcoma.
  • A plain radiograph demonstrated a large, predominantly osteolytic mass in the region of the proximal fibula with features typical of malignant primary bone tumor.
  • The postoperative tissue presented more pleomorphic cells with some definite rhabdomyoblasts.
  • Desmin, actin, Myf4, and MyoD1 were positive in tumor cells, and a diagnosis of rhabdomyosarcoma was eventually made.
  • Only few cases of primary pure bone rhabdomyosarcoma have been reported.
  • Our case does not meet the criteria for sclerosing rhabdomyosarcoma, as matrix formation is focal and cells are spindle-shaped and pleomorphic.
  • [MeSH-major] Bone Neoplasms / diagnosis. Osteosarcoma / diagnosis. Rhabdomyosarcoma / diagnosis
  • [MeSH-minor] Actins / analysis. Adult. Biomarkers, Tumor / analysis. Desmin / analysis. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. MyoD Protein / analysis. Myogenin / analysis

  • Genetic Alliance. consumer health - Osteosarcoma.
  • MedlinePlus Health Information. consumer health - Bone Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17905523.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Actins; 0 / Biomarkers, Tumor; 0 / Desmin; 0 / MYOG protein, human; 0 / MyoD Protein; 0 / MyoD1 myogenic differentiation protein; 0 / Myogenin
  •  go-up   go-down


52. Shah H, Pervez S: Immunophenotypic characterization of high grade pleomorphic sarcomas: a demographic and immunohistochemical study in a major referral center of Pakistan. J Pak Med Assoc; 2005 Mar;55(3):101-4
MedlinePlus Health Information. consumer health - Soft Tissue Sarcoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Immunophenotypic characterization of high grade pleomorphic sarcomas: a demographic and immunohistochemical study in a major referral center of Pakistan.
  • OBJECTIVE: Immunophenotypic characterization of high grade (pleomorphic) sarcomas and determination of their frequency, mean/median age, sex preferences and common sites in Pakistani patients.
  • METHODS: This study included 134 consecutive cases of high grade (pleomorphic) sarcomas diagnosed in adults above the age of 15 years in the section of histopathology at theAga Khan University Hospital, Karachi during a period of two years.
  • These high grade (pleomorphic) sarcomas were immunophenotyped using a panel including antibodies against Vimentin, Desmin, Smooth muscle Actin, S 100, CD34, CD68 and Cytokeratin etc by indirect immunoperoxidase.
  • RESULTS: Of the 134 cases which were characterized, 38.1% were pleomorphic leiomyosarcoma, followed by pleomorphic rhabdomyosarcoma 14.9%, Malignant Peripheral Nerve Sheath Tumour 9%, pleomorphic liposarcoma 3.7% and pleomorphic storiform Malignant Fibrous Histiocytoma 0.7%.
  • Mean/ median age for Leiomyosarcoma was 50/50, for Rhabdomyosarcomas 33/22, for MPNST 42/41, for Liposarcoma 52/50 and for Malignant Fibrous Histiocytoma 46/46 respectively.
  • The commonest site for leiomyosarcoma was lower limb (43%), for rhabdomyosarcoma head and neck (42%), for MPNSTthorax (36.4%) and for liposarcoma abdomen (50%).
  • CONCLUSION: It was concluded that the most common pleomorphic sarcoma occurring in our adult population was Leiomyosarcoma, and that immunohistochemical stains are essential in most cases for further characterization of pleomorphic high grade sarcoma.
  • [MeSH-minor] Adult. Age Distribution. Aged. Antigens, Neoplasm / immunology. Biomarkers, Tumor / analysis. Cross-Sectional Studies. Humans. Immunoenzyme Techniques. Immunohistochemistry. Leiomyosarcoma / pathology. Liposarcoma / genetics. Liposarcoma / pathology. Middle Aged. Nerve Sheath Neoplasms / genetics. Nerve Sheath Neoplasms / pathology. Pakistan. Phenotype. Rhabdomyosarcoma / genetics. Rhabdomyosarcoma / pathology. Surveys and Questionnaires

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15852744.001).
  • [ISSN] 0030-9982
  • [Journal-full-title] JPMA. The Journal of the Pakistan Medical Association
  • [ISO-abbreviation] J Pak Med Assoc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Pakistan
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor
  •  go-up   go-down


53. Thijssens KM, van Ginkel RJ, Suurmeijer AJ, Pras E, van der Graaf WT, Hollander M, Hoekstra HJ: Radiation-induced sarcoma: a challenge for the surgeon. Ann Surg Oncol; 2005 Mar;12(3):237-45
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: From 1978 to 2003, 27 patients--20 females (74%) and 7 males (26%) with a median age 44 years (range, 1-73 years) at the time of diagnosis of the primary tumor--developed an RIS after a median interval of 8 years (range, 3-41 years).
  • The histology of the RIS was 10 (37%) undifferentiated high-grade pleomorphic sarcomas, 7 (26%) angiosarcomas, 6 (22%) fibrosarcomas, 2 (7%) osteosarcomas, 1 (4%) pleomorphic rhabdomyosarcoma, and 1 (4%) pleomorphic leiomyosarcoma.
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Disease-Free Survival. Female. Humans. Infant. Male. Middle Aged. Neoplasm Recurrence, Local. Retrospective Studies. Time Factors. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Soft Tissue Sarcoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15827816.001).
  • [ISSN] 1068-9265
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


54. Buklas D, Kaili D, Taberlet C, Cordier A, Chocron S: Pleomorphic rhabdomyosarcoma pulmonary embolism. Asian Cardiovasc Thorac Ann; 2009 Aug;17(4):435-6
MedlinePlus Health Information. consumer health - Pulmonary Embolism.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pleomorphic rhabdomyosarcoma pulmonary embolism.
  • [MeSH-major] Pulmonary Embolism / etiology. Rhabdomyosarcoma / complications

  • Genetic Alliance. consumer health - Embolism.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19713348.001).
  • [ISSN] 1816-5370
  • [Journal-full-title] Asian cardiovascular & thoracic annals
  • [ISO-abbreviation] Asian Cardiovasc Thorac Ann
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
  •  go-up   go-down


55. Köse R, Kürkçüoğlu IC, Demir D: Surgical management of an inoperable giant pleomorphic rhabdomyosarcoma of the chest wall. J Thorac Oncol; 2009 Sep;4(9):1185

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical management of an inoperable giant pleomorphic rhabdomyosarcoma of the chest wall.
  • [MeSH-major] Rhabdomyosarcoma / surgery. Thoracic Neoplasms / surgery. Thoracic Wall

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19704344.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
  •  go-up   go-down


56. Alhady M, Ngo CT, Tan AK, Swethadri GK, Chua CN: Palpebral pleomorphic rhabdomyosarcoma in a teenager. Eye (Lond); 2007 Feb;21(2):291-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Palpebral pleomorphic rhabdomyosarcoma in a teenager.
  • [MeSH-major] Eyelid Neoplasms / pathology. Rhabdomyosarcoma / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16946759.001).
  • [ISSN] 0950-222X
  • [Journal-full-title] Eye (London, England)
  • [ISO-abbreviation] Eye (Lond)
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
  •  go-up   go-down


57. Chen Y, Lu Y: Primary pleomorphic rhabdomyosarcoma of trunk in an adolescent. J Paediatr Child Health; 2009 Mar;45(3):166-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary pleomorphic rhabdomyosarcoma of trunk in an adolescent.
  • [MeSH-major] Back / pathology. Rhabdomyosarcoma / diagnosis
  • [MeSH-minor] Adolescent. Diagnosis, Differential. Female. Humans

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19317765.001).
  • [ISSN] 1440-1754
  • [Journal-full-title] Journal of paediatrics and child health
  • [ISO-abbreviation] J Paediatr Child Health
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  •  go-up   go-down


58. Liu JP, Cui QC: [Laryngeal pleomorphic rhabdomyosarcoma: report of a case]. Zhonghua Bing Li Xue Za Zhi; 2007 Aug;36(8):573-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Laryngeal pleomorphic rhabdomyosarcoma: report of a case].
  • [MeSH-major] Laryngeal Neoplasms / pathology. Rhabdomyosarcoma / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Histiocytoma, Malignant Fibrous / pathology. Humans. Laryngectomy. Leiomyosarcoma / pathology. Male. Tomography, X-Ray Computed. Vimentin / metabolism

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17980114.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Vimentin
  •  go-up   go-down


59. Paner GP, Gasilionis V, Hammadeh R: A retroperitoneal mass in an elderly woman. Pleomorphic rhabdomyosarcoma, classic variant, with reactive osteoclast-like giant cells. Arch Pathol Lab Med; 2005 May;129(5):703-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A retroperitoneal mass in an elderly woman. Pleomorphic rhabdomyosarcoma, classic variant, with reactive osteoclast-like giant cells.
  • [MeSH-major] Giant Cells / pathology. Osteoclasts / pathology. Retroperitoneal Space / pathology. Rhabdomyosarcoma / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Combined Modality Therapy. Diagnosis, Differential. Embolization, Therapeutic. Female. Humans. Sarcoma / diagnosis. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15859650.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down






Advertisement