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Items 1 to 27 of about 27
1. Lee JY, Wakabayashi T, Yoshida J: Management and survival of pineoblastoma: an analysis of 34 adults from the brain tumor registry of Japan. Neurol Med Chir (Tokyo); 2005 Mar;45(3):132-41; discussion 141-2
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  • [Title] Management and survival of pineoblastoma: an analysis of 34 adults from the brain tumor registry of Japan.
  • Pineoblastoma is a rare tumor in adults, and factors influencing survival are poorly understood.
  • All pineoblastoma cases in adults aged 16 years or older were identified in the BTRJ.
  • Adult pineoblastoma patients have poor survival prognosis.
  • [MeSH-minor] Adolescent. Adult. Age Factors. Aged. Cohort Studies. Female. Humans. Japan / epidemiology. Male. Middle Aged. Models, Statistical. Neurosurgical Procedures / statistics & numerical data. Prognosis. Radiotherapy / statistics & numerical data. Regression Analysis. Retrospective Studies. Sex Factors. Survival Rate. Treatment Outcome

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  • (PMID = 15782004.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
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2. Gasparetto EL, Cruz Jr LC, Doring TM, Araújo B, Dantas MA, Chimelli L, Domingues RC: Diffusion-weighted MR images and pineoblastoma: diagnosis and follow-up. Arq Neuropsiquiatr; 2008 Mar;66(1):64-8
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  • [Title] Diffusion-weighted MR images and pineoblastoma: diagnosis and follow-up.
  • The surgical biopsy defined the diagnosis of pineoblastoma and the therapy was initiated with radiation and chemotherapy.
  • [MeSH-minor] Adult. Diagnosis, Differential. Diffusion Magnetic Resonance Imaging. Follow-Up Studies. Humans. Male

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  • (PMID = 18392417.001).
  • [ISSN] 0004-282X
  • [Journal-full-title] Arquivos de neuro-psiquiatria
  • [ISO-abbreviation] Arq Neuropsiquiatr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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3. Stoiber EM, Schaible B, Herfarth K, Schulz-Ertner D, Huber PE, Debus J, Oertel S: Long term outcome of adolescent and adult patients with pineal parenchymal tumors treated with fractionated radiotherapy between 1982 and 2003--a single institution's experience. Radiat Oncol; 2010;5:122
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  • [Title] Long term outcome of adolescent and adult patients with pineal parenchymal tumors treated with fractionated radiotherapy between 1982 and 2003--a single institution's experience.
  • BACKGROUND: To evaluate the effectivity of fractionated radiotherapy in adolescent and adult patients with pineal parenchymal tumors (PPT).
  • 4 patients had a pineocytoma (PC), one a PPT with intermediate differentiation (PPTID) and 9 patients a pineoblastoma (PB), 2 of which were recurrences.
  • [MeSH-minor] Adolescent. Adult. Female. Follow-Up Studies. Humans. Male. Middle Aged. Radiation Injuries / epidemiology. Radiotherapy / adverse effects. Radiotherapy / methods. Recurrence. Time Factors. Treatment Outcome. Young Adult

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  • [Cites] Stereotact Funct Neurosurg. 1996;66 Suppl 1:164-73 [9032858.001]
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  • (PMID = 21184689.001).
  • [ISSN] 1748-717X
  • [Journal-full-title] Radiation oncology (London, England)
  • [ISO-abbreviation] Radiat Oncol
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3019157
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4. DeBoer R, Batjer H, Marymont M, Goldman S, Walker M, Gottardi-Littell N, Raizer J: Response of an adult patient with pineoblastoma to vorinostat and retinoic acid. J Neurooncol; 2009 Nov;95(2):289-292
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  • [Title] Response of an adult patient with pineoblastoma to vorinostat and retinoic acid.
  • We report the case of an adult patient with pineoblastoma (PBL) who had a complete radiographic response following treatment with vorinostat and retinoic acid.
  • [MeSH-minor] Adult. Combined Modality Therapy. Humans. Hydroxamic Acids / administration & dosage. Male. Prognosis. Radiotherapy Dosage. Treatment Outcome. Tretinoin / administration & dosage

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  • (PMID = 19506816.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Hydroxamic Acids; 5688UTC01R / Tretinoin; 58IFB293JI / vorinostat
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5. Constantine C, Miller DC, Gardner S, Balmaceda C, Finlay J: Osseous metastasis of pineoblastoma: a case report and review of the literature. J Neurooncol; 2005 Aug;74(1):53-7
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  • [Title] Osseous metastasis of pineoblastoma: a case report and review of the literature.
  • PURPOSE: To review the literature on the occurrence of osseous metastases in recurrent pineoblastoma, and to report upon the feasibility and efficacy of treatment using intensive conventional chemotherapy to achieve a remission, followed by consolidation with marrow ablative chemotherapy and autologous hemopoietic stem cell rescue.
  • PATIENT AND METHODS: An adult with isolated extraneural, osseous and bone marrow metastases from a pineoblastoma, received conventional cyclical chemotherapy, followed by consolidation with marrow ablative chemotherapy (thiotepa, carboplatin and temozolomide) and autologous hemopoietic stem cell rescue.
  • CONCLUSIONS: Osseous metastases from pineoblastoma are an extremely rare occurrence.
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols. Combined Modality Therapy. Diagnosis, Differential. Female. Germinoma / pathology. Hematopoietic Stem Cell Transplantation. Humans. Magnetic Resonance Imaging. Treatment Outcome

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  • (PMID = 16078108.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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6. Hinkes BG, von Hoff K, Deinlein F, Warmuth-Metz M, Soerensen N, Timmermann B, Mittler U, Urban C, Bode U, Pietsch T, Schlegel PG, Kortmann RD, Kuehl J, Rutkowski S: Childhood pineoblastoma: experiences from the prospective multicenter trials HIT-SKK87, HIT-SKK92 and HIT91. J Neurooncol; 2007 Jan;81(2):217-23
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  • [Title] Childhood pineoblastoma: experiences from the prospective multicenter trials HIT-SKK87, HIT-SKK92 and HIT91.
  • OBJECTIVE: To analyze the outcome of children with pineoblastoma (PB), treated within the prospective multicenter trials HIT-SKK87, HIT-SKK92 and HIT91 of German-speaking countries.
  • [MeSH-minor] Adolescent. Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Child. Child, Preschool. Combined Modality Therapy. Female. Humans. Male. Prospective Studies. Treatment Outcome

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  • (PMID = 16941074.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
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7. Gill P, Litzow M, Buckner J, Arndt C, Moynihan T, Christianson T, Ansell S, Galanis E: High-dose chemotherapy with autologous stem cell transplantation in adults with recurrent embryonal tumors of the central nervous system. Cancer; 2008 Apr 15;112(8):1805-11
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  • BACKGROUND: Embryonal central nervous system (CNS) tumors (medulloblastoma, cerebral neuroblastoma, pineoblastoma, and primitive neuroectodermal tumors) are rare in adults.
  • The purpose of the current study was to evaluate adult patients with embryonal CNS tumors who were treated with HDC with ASCT and compare their outcomes with those of patients who received conventional-dose chemotherapy.
  • METHODS: The authors reviewed the medical records of 23 adult patients (age >or= 18 years) who were treated at the Mayo Clinic for recurrent embryonal CNS tumors between 1976 and 2004.
  • [MeSH-minor] Adult. Antineoplastic Agents / administration & dosage. Antineoplastic Agents, Alkylating / administration & dosage. Antineoplastic Agents, Phytogenic / administration & dosage. Carmustine / administration & dosage. Cisplatin / administration & dosage. Cohort Studies. Disease Progression. Etoposide / administration & dosage. Female. Follow-Up Studies. Humans. Lomustine / administration & dosage. Male. Middle Aged. Procarbazine / administration & dosage. Retrospective Studies. Survival Rate. Thiotepa / administration & dosage. Transplantation, Autologous

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  • [CommentIn] Cancer. 2008 Apr 15;112(8):1643-5 [18306390.001]
  • (PMID = 18300237.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Antineoplastic Agents, Alkylating; 0 / Antineoplastic Agents, Phytogenic; 35S93Y190K / Procarbazine; 6PLQ3CP4P3 / Etoposide; 7BRF0Z81KG / Lomustine; 905Z5W3GKH / Thiotepa; Q20Q21Q62J / Cisplatin; U68WG3173Y / Carmustine
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8. Parwani AV, Baisden BL, Erozan YS, Burger PC, Ali SZ: Pineal gland lesions: a cytopathologic study of 20 specimens. Cancer; 2005 Apr 25;105(2):80-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The 20 specimens include pineoblastoma (five specimens), pineocytoma (four specimens), astrocytoma (three specimens), germ cell tumor (three specimens), meningioma (one specimen), epidermoid cyst (three specimens), and pineal cyst (one specimen).
  • The unique features included the following: small, hyperchromatic, round to oval cells with frequent rosetting (pineocytoma), with a few specimens in addition showing hypercellularity, crowding, mitoses, and necrosis (pineoblastoma); pleomorphic round cells in a fibrillary background (astrocytoma); large polygonal cells with prominent nucleoli and clear cytoplasm (germ cell tumor); spindled fibroblastic cells (meningioma); anucleate squames and mature squamous cells (epidermoid cyst); and small uniform polygonal cells (pineal cyst).
  • [MeSH-minor] Adolescent. Adult. Astrocytoma / pathology. Biopsy, Fine-Needle. Child. Child, Preschool. Diagnosis, Differential. Epidermal Cyst / pathology. Female. Germinoma / pathology. Humans. Infant. Male. Middle Aged

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  • [Copyright] 2005 American Cancer Society.
  • (PMID = 15662708.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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9. [Application of navigation system ExacTrac in radiation therapy of a female patient with disseminated pineoblastoma]. Zh Vopr Neirokhir Im N N Burdenko; 2010 Jan-Mar;(1):43-6
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  • [Title] [Application of navigation system ExacTrac in radiation therapy of a female patient with disseminated pineoblastoma].
  • We describe 1 illustrative case of a female patient with 2 metastases of pineoblastoma located in left cerebellar hemisphere and at the level of CVII vertebra.
  • [MeSH-minor] Adult. Female. Humans. Neoplasm Metastasis

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  • (PMID = 20429363.001).
  • [ISSN] 0042-8817
  • [Journal-full-title] Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko
  • [ISO-abbreviation] Zh Vopr Neirokhir Im N N Burdenko
  • [Language] rus
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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10. Jain N, Sood N, Wade P, Bandyopadhyay T: An unusual case of headache. Conn Med; 2008 Oct;72(9):525-6
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  • Pinealgland tumors comprise 0.5%-1% of adult brain tumors.
  • Workup revealed a pineoblastoma.
  • [MeSH-minor] Adult. Female. Humans

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  • (PMID = 18833868.001).
  • [ISSN] 0010-6178
  • [Journal-full-title] Connecticut medicine
  • [ISO-abbreviation] Conn Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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11. Fèvre-Montange M, Champier J, Szathmari A, Wierinckx A, Mottolese C, Guyotat J, Figarella-Branger D, Jouvet A, Lachuer J: Microarray analysis reveals differential gene expression patterns in tumors of the pineal region. J Neuropathol Exp Neurol; 2006 Jul;65(7):675-84
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  • To identify molecular markers, using CodeLink oligonucleotide arrays, gene expression was studied in 3 PPTs (2 pineocytomas and one pineoblastoma), 2 PTPRs, and one chordoid glioma, another rare tumor of the third ventricle.
  • The pineocytomas showed high expression of TPH, HIOMT, and genes related to phototransduction in the retina (OPN4, RGS16, and CRB3), whereas the pineoblastoma showed high expression of UBEC2, SOX4, TERT, TEP1, PRAME, CD24, POU4F2, and HOXD13.
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Cluster Analysis. Female. Humans. Infant. Male. Middle Aged. Molecular Sequence Data. Oligonucleotide Array Sequence Analysis

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  • (PMID = 16825954.001).
  • [ISSN] 0022-3069
  • [Journal-full-title] Journal of neuropathology and experimental neurology
  • [ISO-abbreviation] J. Neuropathol. Exp. Neurol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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12. Mandera M, Marcol W, Kotulska K, Olakowska E, Gołka D, Malinowska I, Pietrucha-Dutczak M, Olakowski M, Lewin-Kowalik J: Childhood pineal parenchymal tumors: clinical and therapeutic aspects. Neurosurg Rev; 2010 Apr;34(2):191-6

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  • Records of 27 patients with histologically diagnosed pineocytomas (n=16) and pineoblastoma (n=11) consecutively treated between 1991 and 2001 were reviewed retrospectively to identify factors predictive of aggressiveness.
  • [MeSH-minor] Adolescent. Cerebral Aqueduct / pathology. Chemotherapy, Adjuvant. Child. Child, Preschool. Combined Modality Therapy. Contrast Media. Female. Humans. Hydrocephalus / complications. Hydrocephalus / surgery. Infant. Magnetic Resonance Imaging. Male. Neurosurgical Procedures. Prognosis. Retrospective Studies. Survival Analysis. Tomography, X-Ray Computed. Treatment Outcome. Ventriculoperitoneal Shunt. Ventriculostomy. Young Adult

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  • (PMID = 20924772.001).
  • [ISSN] 1437-2320
  • [Journal-full-title] Neurosurgical review
  • [ISO-abbreviation] Neurosurg Rev
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Contrast Media
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13. Reyns N, Hayashi M, Chinot O, Manera L, Péragut JC, Blond S, Régis J: The role of Gamma Knife radiosurgery in the treatment of pineal parenchymal tumours. Acta Neurochir (Wien); 2006 Jan;148(1):5-11; discussion 11
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  • Two patients with pineoblastoma had tumor size progression out of the initial target requiring several radiosurgery procedures.
  • Two patients with pineoblastoma died because of carcinomatous meningitis or tumor size progression.
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Female. Follow-Up Studies. Humans. Male. Middle Aged. Retrospective Studies. Survival Rate. Treatment Outcome

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  • (PMID = 16172830.001).
  • [ISSN] 0001-6268
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Austria
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14. Papaioannou G, Sebire NJ, McHugh K: Imaging of the unusual pediatric 'blastomas'. Cancer Imaging; 2009;9:1-11
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  • We present examples of the more unusual blastematous pediatric tumors (lipoblastoma, osteoblastoma, chondroblastoma, hemangioblastoma, gonadoblastoma, sialoblastoma, pleuropulmonary blastoma, pancreatoblastoma, pineoblastoma, and medullomyoblastoma) that were recorded in our institution.
  • [MeSH-minor] Adolescent. Brain Neoplasms / diagnosis. Brain Neoplasms / pathology. Brain Neoplasms / radiography. Child. Child, Preschool. Chondroblastoma / pathology. Chondroblastoma / radiography. Female. Gonadoblastoma / radiography. Gonadoblastoma / ultrasonography. Hemangioblastoma / pathology. Hemangioblastoma / radiography. Humans. Infant. Infant, Newborn. Lipoma / diagnosis. Lipoma / pathology. Lipoma / radiography. Lipoma / ultrasonography. Male. Medulloblastoma / pathology. Medulloblastoma / radiography. Osteoblastoma / pathology. Osteoblastoma / radiography. Pancreatic Neoplasms / pathology. Pancreatic Neoplasms / radiography. Pancreatic Neoplasms / ultrasonography. Pineal Gland / pathology. Pineal Gland / radiography. Pinealoma / pathology. Pinealoma / radiography. Salivary Gland Neoplasms / radiography. Salivary Gland Neoplasms / ultrasonography. Thoracic Neoplasms / pathology. Thoracic Neoplasms / radiography. Young Adult

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  • (PMID = 19237343.001).
  • [ISSN] 1470-7330
  • [Journal-full-title] Cancer imaging : the official publication of the International Cancer Imaging Society
  • [ISO-abbreviation] Cancer Imaging
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 52
  • [Other-IDs] NLM/ PMC2651735
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15. Santagata S, Hornick JL, Ligon KL: Comparative analysis of germ cell transcription factors in CNS germinoma reveals diagnostic utility of NANOG. Am J Surg Pathol; 2006 Dec;30(12):1613-8
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  • NANOG was not detected in tumor types frequently considered in the differential diagnosis of CNS germinoma: pineoblastoma, primitive neuroectodermal tumors, medulloblastoma, lymphoma, pituitary adenoma, atypical teratoid/rhabdoid tumor, Langerhans cell histiocytosis, and gliomas.
  • [MeSH-minor] Adolescent. Adult. Alkaline Phosphatase / metabolism. Biomarkers, Tumor / metabolism. Cell Nucleus / metabolism. Child. HMGB Proteins / metabolism. Humans. Isoenzymes / metabolism. Octamer Transcription Factor-3 / metabolism. SOXB1 Transcription Factors. Transcription Factors / metabolism

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  • (PMID = 17122519.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Grant] United States / NINDS NIH HHS / NS / NS047213
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA-Binding Proteins; 0 / HMGB Proteins; 0 / Homeodomain Proteins; 0 / Isoenzymes; 0 / NANOG protein, human; 0 / Octamer Transcription Factor-3; 0 / POU5F1 protein, human; 0 / SOX2 protein, human; 0 / SOXB1 Transcription Factors; 0 / Transcription Factors; 0 / germ-cell AP isoenzyme; EC 3.1.3.1 / Alkaline Phosphatase
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16. Kumar P, Tatke M, Sharma A, Singh D: Histological analysis of lesions of the pineal region: a retrospective study of 12 years. Pathol Res Pract; 2006;202(2):85-92
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  • Glial fibrillary acidic protein (GFAP) stained only the reactive astrocytes in these tumors except two cases of pineoblastoma, which showed GFAP positivity in some tumor cells, indicating glial differentiation.
  • [MeSH-minor] Adolescent. Adult. Cell Differentiation. Child. Child, Preschool. Epidermal Cyst / pathology. Glioma / pathology. Humans. Infant. Male. Middle Aged. Neoplasms, Germ Cell and Embryonal / pathology. Pineal Gland. Retrospective Studies

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  • (PMID = 16413691.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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17. Fukuda T, Akiyama N, Ikegami M, Takahashi H, Sasaki A, Oka H, Komori T, Tanaka Y, Nakazato Y, Akimoto J, Tanaka M, Okada Y, Saito S: Expression of hydroxyindole-O-methyltransferase enzyme in the human central nervous system and in pineal parenchymal cell tumors. J Neuropathol Exp Neurol; 2010 May;69(5):498-510
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  • The proportions of HIOMT-immunoreactive cells successively decreased in the following tumors: pineocytoma, pineal parenchymal tumor of intermediate differentiation, and pineoblastoma.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Animals. Arrestin / metabolism. Cell Line, Tumor. Child. Child, Preschool. Eye Proteins / genetics. Eye Proteins / metabolism. Female. Green Fluorescent Proteins / genetics. Humans. Infant. Male. Middle Aged. Nerve Tissue Proteins / metabolism. Neurons / metabolism. Plant Lectins / metabolism. RNA, Messenger / metabolism. Retina / pathology. Transfection / methods

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  • (PMID = 20418777.001).
  • [ISSN] 1554-6578
  • [Journal-full-title] Journal of neuropathology and experimental neurology
  • [ISO-abbreviation] J. Neuropathol. Exp. Neurol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Arrestin; 0 / Eye Proteins; 0 / Nerve Tissue Proteins; 0 / Plant Lectins; 0 / RNA, Messenger; 0 / Ricinus communis agglutinin-1; 0 / enhanced green fluorescent protein; 147336-22-9 / Green Fluorescent Proteins; EC 2.1.1.4 / Acetylserotonin O-Methyltransferase
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18. Souweidane MM, Morgenstern PF, Christos PJ, Edgar MA, Khakoo Y, Rutka JT, Dunkel IJ: Intraoperative arachnoid and cerebrospinal fluid sampling in children with posterior fossa brain tumors. Neurosurgery; 2009 Jul;65(1):72-8; discussion 78
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  • Arachnoid infiltration and CSF cytology were found in 20.0% and 44.8%, respectively, for medulloblastoma/pineoblastoma (primitive neuroectodermal tumor), 6.9% and 3.6% for pilocytic astrocytoma, and 0.0% and 33.3% for ependymoma.
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Cohort Studies. Female. Humans. Infant. Magnetic Resonance Imaging. Male. Middle Aged. Retrospective Studies. Young Adult

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  • (PMID = 19574827.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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19. Mangels KJ, Johnson MD, Weil RJ: 35-year-old woman with progressive bilateral leg weakness. Brain Pathol; 2006 Apr;16(2):183-4, 187

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  • Once metastasis, including drop metastasis from pigmented medulloblastomas, have been excluded, the differential includes pigmented meningiomas and schwannomas (solitary or as part of Carney complex), as well as other pigmented CNS tumors such as ependymoma and pineoblastoma and systemic diseases such as lymphoma . . .
  • [MeSH-minor] Adult. Female. Functional Laterality. Humans. Thoracic Vertebrae. Treatment Outcome

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  • (PMID = 16768759.001).
  • [ISSN] 1015-6305
  • [Journal-full-title] Brain pathology (Zurich, Switzerland)
  • [ISO-abbreviation] Brain Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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20. Burzynski SR, Weaver RA, Janicki T, Szymkowski B, Jurida G, Khan M, Dolgopolov V: Long-term survival of high-risk pediatric patients with primitive neuroectodermal tumors treated with antineoplastons A10 and AS2-1. Integr Cancer Ther; 2005 Jun;4(2):168-77
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  • Primitive neuroectodermal tumors (PNETs) are usually successfully treated with craniospinal radiation and chemotherapy; however, difficulties with standard treatment can be encountered in very young children, in adult patients at high risk of complication from standard treatment, and in patients with recurrent tumors.
  • Medulloblastoma was diagnosed in 8 patients, pineoblastoma in 3 patients, and other PNET in 2 patients.

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  • (PMID = 15911929.001).
  • [ISSN] 1534-7354
  • [Journal-full-title] Integrative cancer therapies
  • [ISO-abbreviation] Integr Cancer Ther
  • [Language] eng
  • [Publication-type] Clinical Trial; Clinical Trial, Phase II; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Benzeneacetamides; 0 / Drug Combinations; 0 / Phenylacetates; 0 / Piperidones; 0RH81L854J / Glutamine; 104624-98-8 / antineoplaston AS 2-1; 91531-30-5 / antineoplaston A10
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21. Luther N, Stetler WR Jr, Dunkel IJ, Christos PJ, Wellons JC 3rd, Souweidane MM: Subarachnoid dissemination of intraventricular tumors following simultaneous endoscopic biopsy and third ventriculostomy. J Neurosurg Pediatr; 2010 Jan;5(1):61-7
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  • New leptomeningeal disease (1 yolk sac tumor and 1 pineoblastoma) occurred in 2 patients.
  • [MeSH-minor] Adolescent. Adult. Chemotherapy, Adjuvant. Child. Child, Preschool. Combined Modality Therapy. Disease-Free Survival. Female. Follow-Up Studies. Humans. Kaplan-Meier Estimate. Magnetic Resonance Imaging. Male. Middle Aged. Radiotherapy, Adjuvant. Tomography, X-Ray Computed. Young Adult

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  • (PMID = 20043737.001).
  • [ISSN] 1933-0715
  • [Journal-full-title] Journal of neurosurgery. Pediatrics
  • [ISO-abbreviation] J Neurosurg Pediatr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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22. Shibui S, Nomura K: Statistical analysis of pineal tumors based on the data of Brain Tumor Registry of Japan. Prog Neurol Surg; 2009;23:1-11
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  • The most frequent tumor in the pineal region was germinoma, and it accounted for 49.2% of all pineal tumors; it was followed by pineocytoma (8.5%), glioma (6.5%), pineoblastoma (5.1%), malignant teratoma (5.2%) and teratoma (5.1%).
  • Pineoblastoma is most frequent among patients under 5 years of age, while pineocytoma is evenly distributed in patients between 10 and 60 years of age.
  • [MeSH-minor] Adult. Age Distribution. Aged. Female. Glioma / epidemiology. Humans. Incidence. Japan / epidemiology. Male. Middle Aged. Sex Distribution. Teratoma / epidemiology. Young Adult

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  • [Copyright] Copyright (c) 2009 S. Karger AG, Basel.
  • (PMID = 19329857.001).
  • [ISSN] 0079-6492
  • [Journal-full-title] Progress in neurological surgery
  • [ISO-abbreviation] Prog Neurol Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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23. Mori Y, Kobayashi T, Hasegawa T, Yoshida K, Kida Y: Stereotactic radiosurgery for pineal and related tumors. Prog Neurol Surg; 2009;23:106-18
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  • PPT cases were also divided into 2 groups, i.e. pineocytoma (group 3) and pineoblastoma and mixed pineocytoma/pineoblastoma (group 4).
  • Germinoma and pineocytoma showed higher LTC and PFS rates after GKRS, though pineoblastoma was liable to relapse.
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Young Adult

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  • [Copyright] Copyright (c) 2009 S. Karger AG, Basel.
  • (PMID = 19329865.001).
  • [ISSN] 0079-6492
  • [Journal-full-title] Progress in neurological surgery
  • [ISO-abbreviation] Prog Neurol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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24. Kanamori M, Kumabe T, Tominaga T: Is histological diagnosis necessary to start treatment for germ cell tumours in the pineal region? J Clin Neurosci; 2008 Sep;15(9):978-87
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  • The single exception was pineoblastoma.
  • [MeSH-minor] Adolescent. Adult. Aged. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Antineoplastic Protocols / standards. Biomarkers, Tumor / analysis. Child. Child, Preschool. Decision Support Techniques. Female. Humans. Infant. Male. Middle Aged. Neurosurgical Procedures. Predictive Value of Tests. Radiotherapy / methods. Retrospective Studies. Teratoma / diagnosis. Teratoma / metabolism. Teratoma / therapy. Treatment Outcome

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  • (PMID = 18617412.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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25. Kano H, Niranjan A, Kondziolka D, Flickinger JC, Lunsford D: Role of stereotactic radiosurgery in the management of pineal parenchymal tumors. Prog Neurol Surg; 2009;23:44-58
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  • Thirteen patients had pineocytoma, 5 patients had pineoblastoma and 2 patients had mixed pineal parenchymal tumors.
  • [MeSH-minor] Adolescent. Adult. Aged. Biopsy. Child. Child, Preschool. Female. Humans. Kaplan-Meier Estimate. Magnetic Resonance Imaging. Male. Middle Aged. Young Adult

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  • [Copyright] Copyright (c) 2009 S. Karger AG, Basel.
  • (PMID = 19329860.001).
  • [ISSN] 0079-6492
  • [Journal-full-title] Progress in neurological surgery
  • [ISO-abbreviation] Prog Neurol Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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26. Smith AB, Rushing EJ, Smirniotopoulos JG: From the archives of the AFIP: lesions of the pineal region: radiologic-pathologic correlation. Radiographics; 2010 Nov;30(7):2001-20
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  • Neoplasms arising from the pineal parenchyma include the low-grade pineocytoma, pineal parenchymal tumor of intermediate differentiation, and the highly malignant pineoblastoma.
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Female. Humans. Male. Middle Aged. Young Adult

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  • (PMID = 21057132.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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27. Gilheeney SW, Khakoo Y, Souweidane M, Wolden S, Boulad F, Dunkel IJ: Thiotepa/topotecan/carboplatin with autologous stem cell rescue in recurrent/refractory/poor prognosis pediatric malignancies of the central nervous system. Pediatr Blood Cancer; 2010 Apr;54(4):591-5
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  • Five had medulloblastoma (MB), four had high grade glioma (HGG), and one had trilateral retinoblastoma/pineoblastoma (tRB/PB).
  • [MeSH-minor] Adolescent. Carboplatin / administration & dosage. Carboplatin / adverse effects. Child. Child, Preschool. Combined Modality Therapy. Female. Hematopoietic Stem Cell Transplantation. Humans. Male. Neoplasm Recurrence, Local / drug therapy. Prognosis. Thiotepa / administration & dosage. Thiotepa / adverse effects. Topotecan / administration & dosage. Topotecan / adverse effects. Young Adult

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  • (PMID = 19998470.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 7M7YKX2N15 / Topotecan; 905Z5W3GKH / Thiotepa; BG3F62OND5 / Carboplatin
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