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Items 1 to 57 of about 57
1. Genol I, Troyano J, Ariño M, Iglesias I, Arriola P, García-Sánchez J: [Meningocele, glioma and optic nerve meningioma: differential diagnosis and treatment]. Arch Soc Esp Oftalmol; 2009 Nov;84(11):563-8
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  • [Title] [Meningocele, glioma and optic nerve meningioma: differential diagnosis and treatment].
  • [Transliterated title] Meningocele, glioma y meningioma del nervio óptico: diagnóstico diferencial y tratamiento.
  • PURPOSE: After studying 3 clinical cases, we have reviewed the clinical and radiological characteristics of meningocele, meningioma and optic nerve glioma.
  • [MeSH-major] Meningioma / diagnosis. Meningioma / therapy. Meningocele / diagnosis. Meningocele / therapy. Optic Nerve Neoplasms / diagnosis. Optic Nerve Neoplasms / therapy
  • [MeSH-minor] Adult. Child, Preschool. Diagnosis, Differential. Female. Humans. Male. Optic Nerve Glioma / diagnosis. Optic Nerve Glioma / therapy

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  • (PMID = 19967609.001).
  • [ISSN] 1989-7286
  • [Journal-full-title] Archivos de la Sociedad Española de Oftalmología
  • [ISO-abbreviation] Arch Soc Esp Oftalmol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 21
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2. Miyamoto J, Sasajima H, Owada K, Mineura K: Surgical decision for adult optic glioma based on [18F]fluorodeoxyglucose positron emission tomography study. Neurol Med Chir (Tokyo); 2006 Oct;46(10):500-3
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  • [Title] Surgical decision for adult optic glioma based on [18F]fluorodeoxyglucose positron emission tomography study.
  • No FDG was accumulated in the remaining optic tract.
  • The histological diagnosis was optic glioma.
  • Adult optic glioma tends to rapidly extend into the surrounding tissue and to affect the contralateral visual pathway.
  • [MeSH-major] Optic Nerve Glioma / radionuclide imaging. Optic Nerve Glioma / surgery

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  • (PMID = 17062990.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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3. Zhu Y, Harada T, Liu L, Lush ME, Guignard F, Harada C, Burns DK, Bajenaru ML, Gutmann DH, Parada LF: Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation. Development; 2005 Dec;132(24):5577-88
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  • [Title] Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation.
  • Children with this disease suffer a high incidence of optic gliomas, a benign but potentially debilitating tumor of the optic nerve; and an increased incidence of malignant astrocytoma, reactive astrogliosis and intellectual deficits.
  • Primary among these is a developmental defect resulting in global reactive astrogliosis in the adult brain and increased proliferation of glial progenitor cells leading to enlarged optic nerves.
  • As a consequence, all of the mutant optic nerves develop hyperplastic lesions, some of which progress to optic pathway gliomas.
  • These data point to hyperproliferative glial progenitors as the source of the optic tumors and provide a genetic model for NF1-associated astrogliosis and optic glioma.

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  • (PMID = 16314489.001).
  • [ISSN] 0950-1991
  • [Journal-full-title] Development (Cambridge, England)
  • [ISO-abbreviation] Development
  • [Language] ENG
  • [Grant] United States / NINDS NIH HHS / NS / NS052606-01; United States / NINDS NIH HHS / NS / P50 NS052606; United States / NINDS NIH HHS / NS / P50 NS052606-01
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Neurofibromin 1
  • [Other-IDs] NLM/ NIHMS149022; NLM/ PMC2760350
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4. Boschetti M, De Lucchi M, Giusti M, Spena C, Corallo G, Goglia U, Ceresola E, Resmini E, Vera L, Minuto F, Ferone D: Partial visual recovery from radiation-induced optic neuropathy after hyperbaric oxygen therapy in a patient with Cushing disease. Eur J Endocrinol; 2006 Jun;154(6):813-8
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  • [Title] Partial visual recovery from radiation-induced optic neuropathy after hyperbaric oxygen therapy in a patient with Cushing disease.
  • Radiological assessment by contrast-enhanced magnetic resonance (MR) imaging initially suggested the diagnosis of glioma of the optic nerve and the patient started corticosteroid treatment (first with prednisone, 80 mg/day, followed by dexamethasone, 8 mg/day).
  • The clinical evidence was confirmed by the rapid progression of the MR picture, which showed homogeneous enhancement of the chiasm and optic nerves.
  • On the basis of these findings, the original diagnosis of glioma was excluded, and radiation-induced optic neuropathy was diagnosed.
  • Optic neuropathy is an infrequent but dramatic complication of radiation therapy.
  • Here, in addition to describing this particular case, which presented a significantly delayed radiation injury of the optic pathways, we provide a brief literature review and discuss some important points.

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  • (PMID = 16728540.001).
  • [ISSN] 0804-4643
  • [Journal-full-title] European journal of endocrinology
  • [ISO-abbreviation] Eur. J. Endocrinol.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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5. Liu B, Liang YS, Shi XE, Zhang QJ: [Preoperative diagnosis and microsurgery of the optic gliomas:retrospective analysis of 7 patients]. Beijing Da Xue Xue Bao; 2005 Dec 18;37(6):645-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Preoperative diagnosis and microsurgery of the optic gliomas:retrospective analysis of 7 patients].
  • OBJECTIVE: To summarize the clinical characteristics and therapeutic experience of optic gliomas.
  • RESULTS: In this series of optic glioma patients, the average age was 18.7 years, the ratio of men to women was 4:3, and 100% of the tumors were sub-totally removed.
  • CONCLUSION: The optic glioma is benign intracranial tumor with good prognosis.
  • [MeSH-major] Microsurgery / methods. Optic Nerve Glioma / diagnosis. Optic Nerve Glioma / surgery
  • [MeSH-minor] Adolescent. Adult. Child. Diabetes Insipidus / etiology. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neurosurgical Procedures / adverse effects. Neurosurgical Procedures / methods. Postoperative Complications. Retrospective Studies

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  • (PMID = 16378121.001).
  • [ISSN] 1671-167X
  • [Journal-full-title] Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences
  • [ISO-abbreviation] Beijing Da Xue Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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6. Bommakanti K, Panigrahi M, Yarlagadda R, Sundaram C, Uppin MS, Purohit AK: Optic chiasmatic-hypothalamic gliomas: is tissue diagnosis essential? Neurol India; 2010 Nov-Dec;58(6):833-40

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Optic chiasmatic-hypothalamic gliomas: is tissue diagnosis essential?
  • BACKGROUND: Optic chiasmatic-hypothalamic gliomas are sellar-suprasellar lesions with variable radiological features.
  • However, in developing countries, like India infective granulomas (tuberculomas) in the suprasellar region radiologically can mimic optic chiasmatic-hypothalamic gliomas.
  • PATIENTS AND METHODS: The magnetic resonance imaging (MRI) characteristics of 24 patients with either histologically proven optic chiasmatic "pilocytic astrocytoma" or radiologically suspected optic chiasmatic-hypothalamic gliomas were analyzed.
  • Thus, MRI was shown to have a sensitivity of 83.33% and a specificity of 50% for diagnosing optic chiasmatic-hypothalamic gliomas.
  • CONCLUSIONS: Various lesions like craniopharyngiomas, tuberculomas can mimic optic chiasmatic-hypothalamic gliomas radiologically, and it is not possible to diagnose them with certainty on the basis of radiological findings alone.
  • Biopsy and tissue diagnosis should always be sought before instituting radiotherapy or chemotherapy for optic chiasmatic-hypothalamic gliomas.
  • [MeSH-major] Glioma / diagnosis. Hypothalamic Neoplasms / diagnosis. Optic Chiasm / pathology. Optic Nerve Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Biopsy / methods. Child. Child, Preschool. Contrast Media. Female. Humans. Magnetic Resonance Imaging / methods. Male. Young Adult

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  • [CommentIn] Neurol India. 2011 Jan-Feb;59(1):144 [21339694.001]
  • (PMID = 21150045.001).
  • [ISSN] 0028-3886
  • [Journal-full-title] Neurology India
  • [ISO-abbreviation] Neurol India
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Contrast Media
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7. Magalhães FP, Prata TS, Lima VC, Teixeira LF, Manso PG: Multiple wedge-shaped retinal nerve fiber layer defects in a patient with optic nerve glioma in the contralateral eye: case report. Arq Bras Oftalmol; 2009 Jul-Aug;72(4):556-9
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  • [Title] Multiple wedge-shaped retinal nerve fiber layer defects in a patient with optic nerve glioma in the contralateral eye: case report.
  • This case report describes a young non-glaucomatous patient with neurofibromatosis and previous history of optic nerve glioma, which developed multiple wedge-shaped retinal nerve fiber layer defects close to a chorioretinal scar in the fellow eye.
  • After discussing the different possible etiologies to the wedge-shaped defects, the disruption of the nerve fiber layer due to the chorioretinal lesion was considered the most plausible cause.
  • However, further follow-up with visual field assessment, optic nerve head documentation and neuroimaging is mandatory in this case and may provide additional information to better understand it.
  • [MeSH-major] Choroid Diseases / pathology. Cicatrix / pathology. Neurofibromatosis 1 / pathology. Optic Nerve Glioma / pathology. Retinal Diseases / pathology
  • [MeSH-minor] Humans. Magnetic Resonance Imaging. Male. Young Adult

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  • (PMID = 19820802.001).
  • [ISSN] 1678-2925
  • [Journal-full-title] Arquivos brasileiros de oftalmologia
  • [ISO-abbreviation] Arq Bras Oftalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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8. Yatziv Y, Bukstein F, Segev Y, Kesler A: Adult optic nerve glioma presenting as central retinal vein occlusion. Retin Cases Brief Rep; 2007;1(1):33-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adult optic nerve glioma presenting as central retinal vein occlusion.

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  • (PMID = 25390231.001).
  • [ISSN] 1935-1089
  • [Journal-full-title] Retinal cases & brief reports
  • [ISO-abbreviation] Retin Cases Brief Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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9. Tumialán LM, Dhall SS, Biousse V, Newman NJ: Optic nerve glioma and optic neuritis mimicking one another: case report. Neurosurgery; 2005 Jul;57(1):E190; discussion E190
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Optic nerve glioma and optic neuritis mimicking one another: case report.
  • OBJECTIVE AND IMPORTANCE: The clinical and radiographic presentations of optic nerve gliomas and optic neuritis are for the most part distinct and their diagnoses straightforward.
  • We present two cases illustrating the occasional difficulty one can encounter in distinguishing neoplastic from inflammatory optic neuropathies.
  • INTERVENTION: Patient 1 was initially diagnosed with idiopathic retrobulbar optic neuritis.
  • Interval increase of the optic nerve on magnetic resonance imaging prompted a biopsy of the optic nerve, which revealed a pilocytic astrocytoma.
  • Patient 2 was found to have left optic nerve enhancement most consistent with an optic nerve glioma.
  • CONCLUSION: Differentiating between optic nerve neoplasm and inflammation may be difficult.
  • On occasion, the classic clinical finding of pain with eye movement and the radiographic finding of enlargement and enhancement of the optic nerve may be misleading.
  • Open biopsy of the optic nerve is indicated only after a completely negative metabolic, infectious, and inflammatory workup; interval increase of the optic nerve on magnetic resonance imaging; and failure of the patient to recover vision.
  • [MeSH-major] Optic Nerve Glioma / diagnosis. Optic Nerve Glioma / physiopathology. Optic Neuritis / diagnosis. Optic Neuritis / physiopathology
  • [MeSH-minor] Adolescent. Adult. Disease Progression. Female. Humans. Inflammation / etiology. Magnetic Resonance Imaging. Male. Ocular Motility Disorders / etiology. Pain / etiology

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  • (PMID = 15987555.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Grant] United States / NEI NIH HHS / EY / P30-EY06360
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
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10. Zhang TM, An YZ, Liu HC, Wu JP: [Cranial-orbital approach in the treatment of optic nerve glioma]. Zhonghua Yi Xue Za Zhi; 2008 Aug 26;88(33):2309-11
Genetic Alliance. consumer health - Glioma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Cranial-orbital approach in the treatment of optic nerve glioma].
  • OBJECTIVE: To summarize the experience in cranial-orbital approach in the treatment of optic nerve glioma.
  • METHOD: The clinical data of 35 patients with optic nerve glioma diagnosed by CT and MRI, 26 males and 9 females; aged 13 (1 - 54), with the main clinical presentations of visual defection and ex-ophthalmo and with the courses from 1 to 36 months, who underwent operation via the cranial-orbital approach 36 times, were analyzed.
  • CONCLUSION: resection of optic nerve glioma via cranial-orbital approach is effective.
  • However, since residual tumor may remain in the optic nerve canal, post-operative radiation therapy is recommended.
  • [MeSH-major] Optic Nerve Glioma / surgery. Orbit / surgery
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Female. Follow-Up Studies. Humans. Infant. Male. Middle Aged

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  • (PMID = 19087688.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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11. Lena G, Pech-Gourg G, Scavarda D, Klein O, Paz-Paredes A: [Optic nerve glioma in children]. Neurochirurgie; 2010 Apr-Jun;56(2-3):249-56
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Optic nerve glioma in children].
  • [Transliterated title] Gliome du nerf optique chez l'enfant.
  • Optic pathway gliomas are rare tumors accounting for 3-5% of brain tumors in children; 90% are observed in children.
  • Association with NF 1 is classical and the incidence of NF 1 in patients with optic pathway gliomas is estimated at 30-58%.
  • [MeSH-major] Glioma / epidemiology. Optic Nerve Neoplasms / epidemiology
  • [MeSH-minor] Adult. Antineoplastic Agents / therapeutic use. Blindness / etiology. Brain / pathology. Child. Child, Preschool. Exophthalmos / drug therapy. Exophthalmos / epidemiology. Exophthalmos / surgery. Female. Humans. Incidence. Infant. Magnetic Resonance Imaging. Male. Neurofibromatosis 1 / complications. Neurofibromatosis 1 / epidemiology. Neurofibromatosis 1 / pathology. Neurofibromatosis 1 / surgery. Orbit / pathology. Tomography, X-Ray Computed. Visual Acuity

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  • [Copyright] Copyright 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20303553.001).
  • [ISSN] 1773-0619
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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12. Hartel PH, Rosen C, Larzo C, Nestor S: Malignant optic nerve glioma (glioblastoma multiforme): A case report and literature review. W V Med J; 2006 Jul-Aug;102(4):29-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant optic nerve glioma (glioblastoma multiforme): A case report and literature review.
  • Primary gliomas of the optic nerve are very rare.
  • We report a case of a 59-year-old male with sudden vision loss diagnosed with malignant optic nerve glioblastoma multiforme.
  • Magnetic resonance imaging revealed thickening of optic tracts, chiasm, and hypothalamus.
  • In addition to our case, 30 previously reported cases of malignant optic nerve glioma are reviewed.
  • [MeSH-major] Optic Nerve Glioma
  • [MeSH-minor] Adult. Age Factors. Aged. Biopsy. Diagnosis, Differential. Female. Glioblastoma / pathology. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Optic Nerve / pathology. Reoperation. Sex Factors. Visual Fields

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  • (PMID = 17111679.001).
  • [ISSN] 0043-3284
  • [Journal-full-title] The West Virginia medical journal
  • [ISO-abbreviation] W V Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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13. Kaufman LM, Doroftei O: Optic glioma warranting treatment in children. Eye (Lond); 2006 Oct;20(10):1149-64
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Optic glioma warranting treatment in children.
  • PURPOSE: To describe cases of optic pathway glioma (OPG) warranting treatment in children.
  • One patient was successfully treated with an en-bloc optic nerve excision.
  • [MeSH-major] Optic Nerve Glioma / therapy
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Child, Preschool. Disease Progression. Exophthalmos / etiology. Eye Enucleation. Female. Humans. Infant. Magnetic Resonance Imaging. Male. Neoplasm Invasiveness. Neurofibromatosis 1 / complications. Neurofibromatosis 1 / diagnosis. Neurofibromatosis 1 / pathology. Neurofibromatosis 1 / therapy. Optic Nerve / pathology. Optic Nerve / surgery. Retrospective Studies. Treatment Outcome. Vision Disorders / etiology

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  • (PMID = 17019413.001).
  • [ISSN] 0950-222X
  • [Journal-full-title] Eye (London, England)
  • [ISO-abbreviation] Eye (Lond)
  • [Language] eng
  • [Grant] United States / NEI NIH HHS / EY / EY 1792
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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14. Rodríguez-Francia P, Sánchez-Tocino H, García-Cantera M, Martín-Castillo J: [Optic nerve pilocytic astrocytoma with retinal involvement]. Arch Soc Esp Oftalmol; 2005 Dec;80(12):733-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Optic nerve pilocytic astrocytoma with retinal involvement].
  • [Transliterated title] Astrocitoma pilocítico de nervio óptico con afectación de retina.
  • INTRODUCTION: This is an atypical case of a pilocytic astrocytoma that involved the optic nerve (ON) and the retina.
  • [MeSH-major] Optic Nerve Glioma / secondary. Optic Nerve Neoplasms / pathology. Retinal Neoplasms / secondary
  • [MeSH-minor] Adult. Eye Enucleation. Humans. Magnetic Resonance Imaging. Male. Treatment Outcome. Visual Acuity

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  • (PMID = 16372218.001).
  • [ISSN] 0365-6691
  • [Journal-full-title] Archivos de la Sociedad Española de Oftalmología
  • [ISO-abbreviation] Arch Soc Esp Oftalmol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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15. [Optic nerve drusen and decreasing of visual acuity]. Oftalmologia; 2007;51(1):95-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Optic nerve drusen and decreasing of visual acuity].
  • The study of 82 cases with optic disc drusen revealed the following changes of the visual acuity: - normal or slightly lowered visual acuity in 80.5% of cases (66 from 82 cases); - lowered visual acuity (< 0.3) in 19.5% of cases (16 from 82 cases).
  • The lowering of the visual acuity was the consequence of a direct action of the optic disc drusen, of the secondary complications, or also of some associated diseases: amblyopia (2 cases), retinal haemorrhages (4 cases), retinal dystrophies (4 cases), anterior ischemic optic neuropathy (1 case), optic nerve glioma (1 case), macular telangiectasia (1 case), angioid streaks (2 cases).
  • Our results lead to the revision of the concept "optic disc drusen--benign anomaly" and impose additional ocular and general investigations.
  • [MeSH-major] Optic Disk Drusen / physiopathology. Visual Acuity
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Humans. Middle Aged. Reproducibility of Results. Retrospective Studies. Visual Field Tests. Visual Fields

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  • (PMID = 17605280.001).
  • [ISSN] 1220-0875
  • [Journal-full-title] Oftalmologia (Bucharest, Romania : 1990)
  • [ISO-abbreviation] Oftalmologia
  • [Language] rum
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Romania
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16. Majithia A, Liyanage SH, Hewitt R, Grant WE: Adult nasal glioma presenting with visual loss. J Laryngol Otol; 2010 Dec;124(12):1309-13
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adult nasal glioma presenting with visual loss.
  • OBJECTIVES: We report a rare case of a nasal glioma found incidentally in an adult, presenting with visual loss, optic nerve oedema and proptosis.
  • Computed tomography and magnetic resonance imaging showed proptosis, bilateral optic nerve swelling and a heterogeneous mass occupying the left nasal cavity and extending through a skull base defect into the anterior cranial fossa.
  • Biopsy confirmed a nasal glioma.
  • At the multidisciplinary team meeting, it was felt that the nasal glioma probably represented an incidental finding and was not directly responsible for the patient's proptosis and transient visual loss.
  • CONCLUSION: To our knowledge, this is the first report in the English language literature of adult nasal glioma presenting with visual loss.
  • [MeSH-major] Glioma / complications. Nose Neoplasms / complications. Optic Nerve Diseases / complications. Vision Disorders / etiology
  • [MeSH-minor] Adult. Biopsy. Blindness / etiology. Exophthalmos / etiology. Female. Humans. Incidental Findings. Magnetic Resonance Imaging. Male. Papilledema / etiology

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  • (PMID = 20178676.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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17. Tahir MZ, Shaikh F, Siddiqui AA: Primary chiasmal sarcoid granuloma masquerading as glioma of the optic chiasm. J Coll Physicians Surg Pak; 2010 Oct;20(10):695-6
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  • [Title] Primary chiasmal sarcoid granuloma masquerading as glioma of the optic chiasm.
  • MRI scans showed an enlarged optic chiasm.
  • [MeSH-major] Glioma / diagnosis. Optic Chiasm. Optic Nerve Diseases / diagnosis. Optic Nerve Neoplasms / diagnosis. Sarcoidosis / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Granuloma. Humans. Magnetic Resonance Imaging

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  • (PMID = 20943117.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
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18. Kwon Y, Bae JS, Kim JM, Lee DH, Kim SY, Ahn JS, Kim JH, Kim CJ, Kwun BD, Lee JK: Visual changes after gamma knife surgery for optic nerve tumors. Report of three cases. J Neurosurg; 2005 Jan;102 Suppl:143-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Visual changes after gamma knife surgery for optic nerve tumors. Report of three cases.
  • Tumors involving the optic nerve (optic glioma, optic nerve sheath meningioma) are benign but difficult to treat.
  • [MeSH-major] Cranial Nerve Neoplasms / surgery. Exophthalmos / etiology. Meningeal Neoplasms / surgery. Meningioma / surgery. Optic Nerve Glioma / surgery. Optic Nerve Neoplasms / surgery. Postoperative Complications. Radiosurgery / instrumentation. Vision Disorders / etiology
  • [MeSH-minor] Adult. Child. Female. Humans. Magnetic Resonance Imaging. Male. Radiation Dosage. Tumor Burden / radiation effects. Visual Acuity / physiology

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  • (PMID = 15662798.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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19. Fons Martínez MR, España Gregori E, Aviñó Martínez JA, Hernández Pardines F: [An optic nerve tumor in von Hippel-Lindau disease, masquerading as a retinal hemangioma]. Arch Soc Esp Oftalmol; 2006 May;81(5):293-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [An optic nerve tumor in von Hippel-Lindau disease, masquerading as a retinal hemangioma].
  • [Transliterated title] Angioma retiniano como síndrome mascarada de tumor del nervio óptico en la enfermedad de von Hippel-Lindau.
  • An MRI was then performed and showed bilateral tumoral lesions of the optic nerve compatible with a glioma, meningioma or hemangioblastoma.
  • DISCUSSION: The presence of the retinal hemangiomas delayed the diagnosis of an optic nerve tumor in this patient.
  • [MeSH-major] Hemangioma / complications. Hemangioma / diagnosis. Neoplasms, Multiple Primary / diagnosis. Optic Nerve Neoplasms / complications. Optic Nerve Neoplasms / diagnosis. Retinal Neoplasms / complications. Retinal Neoplasms / diagnosis. von Hippel-Lindau Disease / complications
  • [MeSH-minor] Adult. Humans. Male

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  • (PMID = 16752322.001).
  • [ISSN] 0365-6691
  • [Journal-full-title] Archivos de la Sociedad Española de Oftalmología
  • [ISO-abbreviation] Arch Soc Esp Oftalmol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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20. Roselli F, Pisciotta NM, Aniello MS, Niccoli-Asabella A, Defazio G, Livrea P, Rubini G: Brain F-18 Fluorocholine PET/CT for the assessment of optic pathway glioma in neurofibromatosis-1. Clin Nucl Med; 2010 Oct;35(10):838-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Brain F-18 Fluorocholine PET/CT for the assessment of optic pathway glioma in neurofibromatosis-1.
  • Molecular imaging of optic pathway gliomas may be a valuable tool in the selection of therapeutic options.
  • [MeSH-major] Brain. Choline / analogs & derivatives. Glioma / diagnosis. Neurofibromatosis 1 / diagnosis. Optic Nerve. Positron-Emission Tomography. Tomography, X-Ray Computed
  • [MeSH-minor] Humans. Male. Young Adult

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  • (PMID = 20838306.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / fluorocholine; N91BDP6H0X / Choline
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21. Lama G, Esposito Salsano M, Grassia C, Calabrese E, Grassia MG, Bismuto R, Melone MA, Russo S, Scuotto A: Neurofibromatosis type 1 and optic pathway glioma. A long-term follow-up. Minerva Pediatr; 2007 Feb;59(1):13-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neurofibromatosis type 1 and optic pathway glioma. A long-term follow-up.
  • AIM: Optic pathway gliomas (OPG) are the predominant intracranial tumours associated with neurofibromatosis type 1 (NF1).
  • Fifteen out of 200 (7.5%) of these patients (7 males, 8 females) were identified with evidence of optic pathway tumours.
  • All children had evidence of optic pathway tumour on magnetic resonance imaging.
  • Three had a prechiasmal tumour, 2 had a chiasmal tumour, 1 had prechiasmal/chiasmal tumour, 2 had a prechiasmal/chiasmal and postchiasmal tumour, 2 had a chiasmal and postchiasmal tumour, 4 had a massive involvement of the optic system, 1 child exhibited a bilateral involvement of the optic nerves with additional impairment of the chiasm.
  • CONCLUSIONS: Because optic pathway tumours arise in children younger than 6 years of age, all NF1 children should undergo yearly ophtalmologic examination and growth assessment to monitor signs of precocious puberty.
  • [MeSH-major] Neurofibromatosis 1 / epidemiology. Optic Nerve Glioma / epidemiology. Visual Pathways / pathology
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Female. Follow-Up Studies. Humans. Infant. Intracranial Hypertension / epidemiology. Magnetic Resonance Imaging. Male. Optic Chiasm / pathology. Prevalence. Remission, Spontaneous. Retrospective Studies. Severity of Illness Index. Time Factors


22. Combs SE, Schulz-Ertner D, Moschos D, Thilmann C, Huber PE, Debus J: Fractionated stereotactic radiotherapy of optic pathway gliomas: tolerance and long-term outcome. Int J Radiat Oncol Biol Phys; 2005 Jul 1;62(3):814-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fractionated stereotactic radiotherapy of optic pathway gliomas: tolerance and long-term outcome.
  • PURPOSE: To evaluate the effectiveness and toxicity of fractionated stereotactically guided radiotherapy (FSRT) in the management of optic glioma.
  • METHODS AND MATERIALS: Fifteen patients with optic pathway gliomas were treated with FSRT at our institution between 1990 and 2003.
  • The good tumor control and the potential of sparing normal brain tissue, especially the pituitary gland in lesions involving the optic chiasm, permit effective treatment of patients with optic nerve gliomas.
  • [MeSH-major] Optic Nerve Glioma / surgery. Radiosurgery / methods
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Dose Fractionation. Female. Humans. Infant. Male. Radiation Tolerance. Stereotaxic Techniques

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  • (PMID = 15936565.001).
  • [ISSN] 0360-3016
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
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23. Sharif S, Ferner R, Birch JM, Gillespie JE, Gattamaneni HR, Baser ME, Evans DG: Second primary tumors in neurofibromatosis 1 patients treated for optic glioma: substantial risks after radiotherapy. J Clin Oncol; 2006 Jun 1;24(16):2570-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Second primary tumors in neurofibromatosis 1 patients treated for optic glioma: substantial risks after radiotherapy.
  • PURPOSE: Optic pathway gliomas (OPGs) are the most common CNS tumor in neurofibromatosis 1 (NF1) patients.
  • [MeSH-major] Neoplasms, Second Primary / etiology. Neurofibromatosis 1 / complications. Optic Nerve Glioma / radiotherapy
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Female. Follow-Up Studies. Humans. Infant. Male. Radiotherapy / adverse effects. Radiotherapy / contraindications. Risk Assessment. Risk Factors

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  • (PMID = 16735710.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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24. Kelly JP, Weiss AH: Comparison of pattern visual-evoked potentials to perimetry in the detection of visual loss in children with optic pathway gliomas. J AAPOS; 2006 Aug;10(4):298-306
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comparison of pattern visual-evoked potentials to perimetry in the detection of visual loss in children with optic pathway gliomas.
  • VEPs can be a reliable and objective alternative for the detection of visual loss due to optic pathway glioma in children who are intolerant to visual field testing.

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  • [CommentIn] J AAPOS. 2006 Aug;10(4):293-5 [16935225.001]
  • (PMID = 16935227.001).
  • [ISSN] 1091-8531
  • [Journal-full-title] Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
  • [ISO-abbreviation] J AAPOS
  • [Language] ENG
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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25. Segal L, Darvish-Zargar M, Dilenge ME, Ortenberg J, Polomeno RC: Optic pathway gliomas in patients with neurofibromatosis type 1: follow-up of 44 patients. J AAPOS; 2010 Apr;14(2):155-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Optic pathway gliomas in patients with neurofibromatosis type 1: follow-up of 44 patients.
  • BACKGROUND: Children born with neurofibromatosis type 1 (NF1) have an increased risk of developing optic pathway gliomas (OPGs) during childhood.
  • These 8 patients all demonstrated chiasmal and/or retrochiasmal tumor in addition to nerve involvement.
  • The location of OPG as demonstrated on magnetic resonance imaging (MRI) cannot be used as a prognostic indicator because visual outcomes were similar between optic nerve/chiasmal and retrochiasmal tumors.

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  • [Copyright] Copyright 2010 American Association for Pediatric Ophthalmology and Strabismus. Published by Mosby, Inc. All rights reserved.
  • (PMID = 20451859.001).
  • [ISSN] 1528-3933
  • [Journal-full-title] Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
  • [ISO-abbreviation] J AAPOS
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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26. Serova NK, Lazareva LA, Ozerova VI, Pronin IN, Gorelychev SK: [Specific features of manifestation of anterior optic tract gliomas in patients with type 1 neurofibromatosis: ophthalmological and neurovisualizational aspects]. Vestn Oftalmol; 2006 Nov-Dec;122(6):36-9
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  • [Title] [Specific features of manifestation of anterior optic tract gliomas in patients with type 1 neurofibromatosis: ophthalmological and neurovisualizational aspects].
  • Gliomas of the anterior optic tract (AOT) (optic nerves, chiasms, and visual tracts) are benign slowly growing tumors usually detectable in childhood.
  • [MeSH-major] Neurofibromatosis 2 / complications. Optic Chiasm. Optic Nerve Glioma / diagnosis. Visual Pathways
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Female. Humans. Infant. Magnetic Resonance Imaging. Male. Tomography, X-Ray Computed. Visual Acuity

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  • (PMID = 17217201.001).
  • [ISSN] 0042-465X
  • [Journal-full-title] Vestnik oftalmologii
  • [ISO-abbreviation] Vestn Oftalmol
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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27. Kebudi R, Tuncer S, Upadhyaya M, Peksayar G, Spurlock G, Yazici H: A novel mutation in the NF1 gene in two siblings with neurofibromatosis type 1 and bilateral optic pathway glioma. Pediatr Blood Cancer; 2008 Mar;50(3):713-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A novel mutation in the NF1 gene in two siblings with neurofibromatosis type 1 and bilateral optic pathway glioma.
  • [MeSH-major] Codon, Nonsense. Genes, Neurofibromatosis 1. Neoplasms, Multiple Primary / genetics. Neurofibromatosis 1 / genetics. Optic Nerve Glioma / genetics. Point Mutation
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Base Sequence. Carboplatin / administration & dosage. Carboplatin / adverse effects. Child, Preschool. Exons / genetics. Female. Germ-Line Mutation. Heteroduplex Analysis. Humans. Infant. Molecular Sequence Data. Siblings. Vincristine / administration & dosage


28. Chang BC, Mirabella G, Yagev R, Banh M, Mezer E, Parkin PC, Westall CA, Buncic JR: Screening and diagnosis of optic pathway gliomas in children with neurofibromatosis type 1 by using sweep visual evoked potentials. Invest Ophthalmol Vis Sci; 2007 Jun;48(6):2895-902
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Screening and diagnosis of optic pathway gliomas in children with neurofibromatosis type 1 by using sweep visual evoked potentials.
  • Up to 24% of these patients have optic pathway gliomas (OPGs).
  • [MeSH-major] Contrast Sensitivity / physiology. Diagnostic Techniques, Ophthalmological. Evoked Potentials, Visual. Neurofibromatosis 1 / diagnosis. Optic Nerve Glioma / diagnosis. Optic Nerve Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Female. Humans. Male. Vision Screening / methods. Visual Acuity. Visual Pathways / pathology

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  • (PMID = 17525226.001).
  • [ISSN] 0146-0404
  • [Journal-full-title] Investigative ophthalmology & visual science
  • [ISO-abbreviation] Invest. Ophthalmol. Vis. Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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29. Scheithauer BW, Erdogan S, Rodriguez FJ, Burger PC, Woodruff JM, Kros JM, Gokden M, Spinner RJ: Malignant peripheral nerve sheath tumors of cranial nerves and intracranial contents: a clinicopathologic study of 17 cases. Am J Surg Pathol; 2009 Mar;33(3):325-38
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  • [Title] Malignant peripheral nerve sheath tumors of cranial nerves and intracranial contents: a clinicopathologic study of 17 cases.
  • Malignant peripheral nerve sheath tumors (MPNSTs) arising from cranial nerves or their branches are very uncommon.
  • In addition, 1 tumor involved the optic chiasm (n=1).
  • Four patients had postirradiation malignant peripheral nerve sheath tumors, 2 having been treated for optic chiasm glioma, both being NF1 affected.
  • Malignant cranial nerve sheath tumors are rare and are associated with the same poor prognosis as those of spinal nerves at other sites.
  • [MeSH-major] Brain Neoplasms / pathology. Cranial Nerve Neoplasms / pathology. Nerve Sheath Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Child, Preschool. Female. Humans. Immunohistochemistry. Male. Middle Aged

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  • (PMID = 19065105.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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30. Wu-Chen WY, Jacobs DA, Volpe NJ, Dalmau JO, Moster ML: Intracranial malignancies occurring more than 20 years after radiation therapy for pituitary adenoma. J Neuroophthalmol; 2009 Dec;29(4):289-95
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  • A 37-year-old woman developed a left third cranial nerve palsy 28 years after radiation for a nonsecreting pituitary adenoma.
  • The brainstem abnormality was presumptively diagnosed as a malignant glioma.
  • A 63-year-old man developed a malignant astrocytoma of the left optic nerve and chiasm 23 years after partial excision and radiation of a nonsecreting pituitary adenoma.
  • [MeSH-major] Adenoma / radiotherapy. Brain Stem Neoplasms / etiology. Glioma / etiology. Neoplasms, Radiation-Induced / etiology. Neoplasms, Second Primary / etiology. Optic Nerve Neoplasms / etiology. Pituitary Neoplasms / radiotherapy
  • [MeSH-minor] Adult. Fatal Outcome. Female. Humans. Male. Middle Aged. Time Factors

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  • (PMID = 19952902.001).
  • [ISSN] 1536-5166
  • [Journal-full-title] Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
  • [ISO-abbreviation] J Neuroophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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31. Takei H, Florez L, Moroz K, Bhattacharjee MB: Medulloepithelioma: Two unusual locations. Pathol Int; 2007 Feb;57(2):91-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • MRI demonstrated diffuse, fusiform, and contrast-enhancing enlargement of the left optic nerve.
  • The main differential diagnoses include an immature teratoma and an optic nerve glioma in cases 1 and 2, respectively.
  • [MeSH-major] Neuroectodermal Tumors, Primitive / diagnosis. Optic Nerve Neoplasms / diagnosis. Spinal Neoplasms / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Gene Expression Regulation, Neoplastic. Glioma / diagnosis. Glioma / pathology. Humans. Infant. Intermediate Filament Proteins / genetics. Intermediate Filament Proteins / metabolism. Lumbosacral Region. Magnetic Resonance Imaging. Male. Nerve Tissue Proteins / genetics. Nerve Tissue Proteins / metabolism. Nestin. Synaptophysin / genetics. Synaptophysin / metabolism. Teratoma / diagnosis. Teratoma / pathology

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  • (PMID = 17300673.001).
  • [ISSN] 1320-5463
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Intermediate Filament Proteins; 0 / NES protein, human; 0 / Nerve Tissue Proteins; 0 / Nestin; 0 / Synaptophysin
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32. Rudnik A, Zawadzki T, Wojtacha M, Bazowski P, Gamrot J, Galuszka-Ignasiak B, Duda I: Endoscopic transnasal transsphenoidal treatment of pathology of the sellar region. Minim Invasive Neurosurg; 2005 Apr;48(2):101-7
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  • In one case the diagnosis was craniopharyngioma, in 1 chordoma of the clivus, in one glioma of the optic nerve, in 1 the reason for an operation was an empty sella syndrome and in 3 cases the pathological diagnosis was an amorphous masses.
  • [MeSH-major] Endoscopy / methods. Nasal Cavity / surgery. Optic Nerve Glioma / surgery. Pituitary Diseases / surgery. Skull Base Neoplasms / surgery. Sphenoid Sinus / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Female. Humans. Length of Stay. Male. Middle Aged. Sella Turcica / pathology. Sella Turcica / surgery. Treatment Outcome

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  • (PMID = 15906205.001).
  • [ISSN] 0946-7211
  • [Journal-full-title] Minimally invasive neurosurgery : MIN
  • [ISO-abbreviation] Minim Invasive Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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33. Karcioglu ZA, Mascott CR: Computer-assisted image-guided orbit surgery. Eur J Ophthalmol; 2006 May-Jun;16(3):446-52
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  • RESULTS: The applications of image-guided stereotactic surgery proved to be beneficial in three extensive orbital tumors, including optic nerve glioma, recurrent pleomorphic adenoma of lacrimal gland, and secondary orbital meningioma.
  • [MeSH-minor] Adenoma, Pleomorphic / pathology. Adenoma, Pleomorphic / surgery. Adult. Aged. Child. Female. Humans. Magnetic Resonance Imaging. Male. Meningioma / pathology. Meningioma / surgery. Neoplasm Invasiveness. Neoplasm Recurrence, Local. Optic Nerve Glioma / pathology. Optic Nerve Glioma / surgery. Tomography, X-Ray Computed

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  • (PMID = 16761248.001).
  • [ISSN] 1120-6721
  • [Journal-full-title] European journal of ophthalmology
  • [ISO-abbreviation] Eur J Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Italy
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34. Moharir M, London K, Howman-Giles R, North K: Utility of positron emission tomography for tumour surveillance in children with neurofibromatosis type 1. Eur J Nucl Med Mol Imaging; 2010 Jul;37(7):1309-17
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  • PURPOSE: There is little consensus regarding optimal surveillance of optic pathway glioma (OPG) and plexiform neurofibroma (PNF) in childhood neurofibromatosis type 1 (NF1). (18)F-2-Fluoro-2-deoxy-D: -glucose (FDG) positron emission tomography and computed tomography (PET/CT) is employed in the surveillance of adult PNFs; but its utility has neither been specifically studied in children with PNFs nor in children with OPG.
  • The two grade 3 PNFs were confirmed malignant peripheral nerve sheath tumours.
  • [MeSH-minor] Adult. Child. Child, Preschool. Female. Fluorodeoxyglucose F18. Humans. Male. Neurofibroma, Plexiform / diagnostic imaging. Optic Nerve Glioma / diagnostic imaging. Retrospective Studies. Tomography, X-Ray Computed

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  • [Cites] Neurofibromatosis. 1988;1(3):172-8 [3152465.001]
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  • (PMID = 20179923.001).
  • [ISSN] 1619-7089
  • [Journal-full-title] European journal of nuclear medicine and molecular imaging
  • [ISO-abbreviation] Eur. J. Nucl. Med. Mol. Imaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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35. Jalali R, Mallick I, Dutta D, Goswami S, Gupta T, Munshi A, Deshpande D, Sarin R: Factors influencing neurocognitive outcomes in young patients with benign and low-grade brain tumors treated with stereotactic conformal radiotherapy. Int J Radiat Oncol Biol Phys; 2010 Jul 15;77(4):974-9
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  • METHODS AND MATERIALS: Twenty-eight patients (median age, 13 years) with residual/progressive brain tumors (10 craniopharyngioma, 8 cerebellar astrocytoma, 6 optic pathway glioma and 4 cerebral low-grade glioma) were treated with SCRT to a dose of 54 Gy in 30 fractions over 6 weeks.
  • [MeSH-major] Brain Neoplasms / radiotherapy. Cognition Disorders / etiology. Glioma / radiotherapy. Intelligence / radiation effects
  • [MeSH-minor] Adolescent. Astrocytoma / radiotherapy. Cerebellar Neoplasms / psychology. Cerebellar Neoplasms / radiotherapy. Child. Cognition / radiation effects. Craniopharyngioma / psychology. Craniopharyngioma / radiotherapy. Female. Humans. Male. Optic Nerve Glioma / radiotherapy. Prospective Studies. Radiotherapy, Conformal / methods. Young Adult

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 19864079.001).
  • [ISSN] 1879-355X
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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36. Shkarubo AN, Serova NK, Tropinskaia OF, Shishkina LV, Pronin IN: [Chiasmatic cavernoma]. Zh Vopr Neirokhir Im N N Burdenko; 2005 Apr-Jun;(2):20-1; discussion 21-2

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  • Hemorrhage into the structures of the anterior visual pathway, apoplexy of the chiasma or optic nerves, is a rare pathology that can be caused by different pathological processes among which cavernous angioma and arteriovenous malformation are more frequently mentioned.
  • The cause of chiasmatic apoplexy may be also hemorrhage into the tumor--chiasmatic glioma of blood penetration into the chiasma in pituitary apoplexy.
  • In addition to acute visual disorders suggesting the involvement of the left optic nerve, chiasma, and left visual pathway, 23-year-old patient had endocrine disorders as polyuria, polydipsia, which first suggests craniopharyngioma and glioma of the chiasma.
  • A capsule and hematomic clots were removed from the thickened left optic nerve and left chiasmatic half during surgery.
  • [MeSH-major] Hemangioma, Cavernous / diagnosis. Hemangioma, Cavernous / surgery. Optic Nerve Neoplasms / diagnosis. Optic Nerve Neoplasms / surgery
  • [MeSH-minor] Adult. Diagnostic Techniques, Ophthalmological. Humans. Magnetic Resonance Imaging. Male. Neurosurgical Procedures. Ophthalmologic Surgical Procedures. Optic Chiasm / pathology. Stroke / etiology. Tomography, X-Ray Computed / methods

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  • (PMID = 16078630.001).
  • [ISSN] 0042-8817
  • [Journal-full-title] Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko
  • [ISO-abbreviation] Zh Vopr Neirokhir Im N N Burdenko
  • [Language] rus
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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37. Trivin C, Couto-Silva AC, Sainte-Rose C, Chemaitilly W, Kalifa C, Doz F, Zerah M, Brauner R: Presentation and evolution of organic central precocious puberty according to the type of CNS lesion. Clin Endocrinol (Oxf); 2006 Aug;65(2):239-45
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  • These were optic glioma or astrocytoma (n = 45), hydrocephalus (n = 22), hypothalamic hamartoma (n = 15), suprasellar arachnoid cyst (n = 10) and others (n = 8).
  • The boys with hamartoma were significantly taller and had greater bone age advance, LH peak and testosterone than boys with optic glioma.
  • All patients treated for optic glioma had hypothalamic-pituitary deficiencies, including GH (100%), thyrotrophin (71.4%), corticotrophin (12.5%) and pubertal (34.3%) deficiencies.
  • [MeSH-minor] Adolescent. Adult. Arachnoid Cysts / blood. Arachnoid Cysts / complications. Astrocytoma / blood. Astrocytoma / complications. Body Height. Child. Child, Preschool. Female. Follicle Stimulating Hormone / blood. Gonadal Steroid Hormones / blood. Growth Hormone / blood. Growth Hormone-Releasing Hormone. Hamartoma / blood. Hamartoma / complications. Humans. Hydrocephalus / blood. Hydrocephalus / complications. Hydrocortisone / blood. Hypothalamic Neoplasms / blood. Hypothalamic Neoplasms / complications. Luteinizing Hormone / blood. Male. Meningomyelocele / blood. Meningomyelocele / complications. Optic Nerve Glioma / blood. Optic Nerve Glioma / complications. Statistics, Nonparametric


38. Kotaska K, Petrak B, Kukacka J, Kraus J, Prusa R: Anti-vimentin antibodies and neuron-specific enolase in children with neurofibromatosis type-1. Neuro Endocrinol Lett; 2007 Dec;28(6):761-4
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  • OBJECTIVES: The aim of the study was to investigate the relationship of serum levels of neuron-specific enolase, anti-vimentin IgG, and anti-vimentin IgM antibodies in patients with neurofibromatosis type 1 and associated tumors (optic glioma, and plexiform neurofibroma).
  • [MeSH-major] Central Nervous System Neoplasms / immunology. Neurofibroma, Plexiform / immunology. Neurofibromatosis 1 / immunology. Optic Nerve Glioma / immunology. Phosphopyruvate Hydratase / blood. Skin Neoplasms / immunology. Vimentin / immunology
  • [MeSH-minor] Adolescent. Adult. Antibody Formation / immunology. Biomarkers / blood. Biomarkers, Tumor / blood. Child. Child, Preschool. Female. Humans. Immunoglobulin G / blood. Immunoglobulin M / blood. Infant. Male. Sensitivity and Specificity. Statistics, Nonparametric

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  • (PMID = 18063947.001).
  • [ISSN] 0172-780X
  • [Journal-full-title] Neuro endocrinology letters
  • [ISO-abbreviation] Neuro Endocrinol. Lett.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Sweden
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Biomarkers, Tumor; 0 / Immunoglobulin G; 0 / Immunoglobulin M; 0 / Vimentin; EC 4.2.1.11 / Phosphopyruvate Hydratase
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39. Harder A, Titze S, Herbst L, Harder T, Guse K, Tinschert S, Kaufmann D, Rosenbaum T, Mautner VF, Windt E, Wahlländer-Danek U, Wimmer K, Mundlos S, Peters H: Monozygotic twins with neurofibromatosis type 1 (NF1) display differences in methylation of NF1 gene promoter elements, 5' untranslated region, exon and intron 1. Twin Res Hum Genet; 2010 Dec;13(6):582-94
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  • Furthermore, we detected significant intra-pair differences in cytosine methylation for the region from -249 to -234 with regard to discordance for optic glioma with a higher grade of methylation in glioma cases.
  • [MeSH-minor] Adolescent. Adult. Child. Epigenomics. Exons / genetics. Female. Haploinsufficiency. Humans. Introns / genetics. Lymphocytes / metabolism. Lymphocytes / pathology. Male. Optic Nerve Glioma / genetics. Promoter Regions, Genetic / genetics

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  • (PMID = 21142935.001).
  • [ISSN] 1832-4274
  • [Journal-full-title] Twin research and human genetics : the official journal of the International Society for Twin Studies
  • [ISO-abbreviation] Twin Res Hum Genet
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Twin Study
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Neurofibromin 1; 0 / Untranslated Regions
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40. Mehta JS, Plant GT, Acheson JF: Twin and triple peaks papilledema. Ophthalmology; 2005 Jul;112(7):1299-301
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  • PURPOSE: To describe 2 adult patients who presented with papilledema after band atrophy (i.e., twin and triple peaks papilledema).
  • The second patient developed twin peaks papilledema due to a chiasmal glioma causing secondary raised intracranial pressure.
  • [MeSH-major] Glioma / complications. Optic Chiasm / pathology. Optic Nerve Neoplasms / complications. Papilledema / etiology. Pituitary Neoplasms / complications. Prolactinoma / complications
  • [MeSH-minor] Adult. Female. Humans. Intracranial Hypertension. Magnetic Resonance Imaging. Male. Middle Aged. Retrospective Studies. Tomography, Optical Coherence

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  • (PMID = 15921750.001).
  • [ISSN] 1549-4713
  • [Journal-full-title] Ophthalmology
  • [ISO-abbreviation] Ophthalmology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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41. Silva LL, Barbosa-Coutinho LM: [Orbito-sphenoidal expansive processes: an anatomopathological study of 82 cases]. Arq Bras Oftalmol; 2009 Jan-Feb;72(1):84-90
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  • [Transliterated title] Processos expansivos orbitoesfenoidais: estudo anatomopatológico de 82 casos.
  • PURPOSE: To describe the orbito-sphenoidal expansive processes diagnosed at the Anatomo-Pathological Laboratory of the Fundação Faculdade Federal de Ciências Médicas de Porto Alegre - Complexo Hospitalar Santa Casa de Porto Alegre during a period of 15 years, evaluating their relative frequencies among other tumoral processes.
  • Children presented more frequently optic nerve gliomas (4 of 6 cases 66.6%), retinoblastomas (4 cases - 100%) and rhabdomyosarcomas (3 of 4 cases - 75%).
  • Less frequent diseases in children were optic nerve meningioma, neurofibroma, inflammatory pseudotumor, chronic dacryoadenitis, neuroma and chronic inflammatory process.
  • The adult population presented more cases of basal cell carcinomas (18 cases), squamous cell carciomas (12 cases), meningiomas (10 cases), choroidal malignant melanoma (3 cases) and lacrimal gland tumors (7 cases).
  • [MeSH-major] Carcinoma / epidemiology. Optic Nerve Glioma / epidemiology. Orbital Neoplasms / epidemiology. Retinoblastoma / epidemiology. Rhabdomyosarcoma / epidemiology
  • [MeSH-minor] Adolescent. Adult. Age Distribution. Aged. Aged, 80 and over. Brazil / epidemiology. Child. Child, Preschool. Female. Humans. Incidence. Infant. Male. Middle Aged. Young Adult

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  • (PMID = 19347129.001).
  • [ISSN] 1678-2925
  • [Journal-full-title] Arquivos brasileiros de oftalmologia
  • [ISO-abbreviation] Arq Bras Oftalmol
  • [Language] por
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Brazil
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42. Friedrich RE, Stelljes C, Hagel C, Giese M, Scheuer HA: Dysplasia of the orbit and adjacent bone associated with plexiform neurofibroma and ocular disease in 42 NF-1 patients. Anticancer Res; 2010 May;30(5):1751-64
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  • Alterations of the optic nerve and adjacent structures were identified on MRI or CT in 14 patients.
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Female. Glioma / pathology. Humans. Infant. Magnetic Resonance Imaging / methods. Male. Optic Nerve / pathology. Phenotype. Skull / pathology. Soft Tissue Neoplasms / metabolism. Tomography, X-Ray Computed / methods

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  • (PMID = 20592374.001).
  • [ISSN] 1791-7530
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
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43. Xu D, Liu D, Zhang Z, Zhang Y, Li Y, Liu X, Jia Q, Zheng L, Song G: Gamma Knife surgery in the management of orbital tumors. J Neurosurg; 2010 Dec;113 Suppl:34-8

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  • There were 84 meningiomas, 38 epithelial tumors of the lacrimal gland, 23 schwannomas, 18 malignant choroidal melanomas, 12 optic nerve gliomas, 11 orbital metastases, 10 pseudotumors of the orbit, 3 retinoblastomas, and 3 cases of fibromatosis.
  • [MeSH-major] Meningioma / surgery. Neurilemmoma / surgery. Optic Nerve Glioma / surgery. Orbital Neoplasms / surgery. Radiosurgery / instrumentation
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Disease-Free Survival. Female. Humans. Male. Meningeal Neoplasms / surgery. Middle Aged. Radiotherapy Dosage. Retrospective Studies. Treatment Outcome

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  • (PMID = 21121785.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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44. Kawai N, Okauchi M, Miyake K, Sasakawa Y, Yamamoto Y, Nishiyama Y, Tamiya T: [11C-methionine positron emission tomography in nontumorous brain lesions]. No Shinkei Geka; 2010 Nov;38(11):985-95
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  • Idiopathic orbital and optic inflammations showed mildly increased MET uptake in the lesions.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Brain Abscess / radionuclide imaging. Carbon Radioisotopes. Cerebral Infarction / radionuclide imaging. Encephalocele / radionuclide imaging. Female. Glioma / radionuclide imaging. Humans. Male. Middle Aged. Nervous System Diseases / radionuclide imaging. Optic Nerve Diseases / radionuclide imaging. Orbital Diseases / radionuclide imaging

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  • (PMID = 21081810.001).
  • [ISSN] 0301-2603
  • [Journal-full-title] No shinkei geka. Neurological surgery
  • [ISO-abbreviation] No Shinkei Geka
  • [Language] jpn
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Carbon Radioisotopes; AE28F7PNPL / Methionine
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45. Czajkowski G, Kałuzny J, Jatczak-Gaca A, Wysocki M: [Neurofibromatosis type 1--own experiences]. Klin Oczna; 2010;112(1-3):45-8
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  • The most common were café-au-lait spots on the lids, Lisch nodules on the iris, changes in CNS, especially gliomas of the optic pathway, nodular neurofibromas in the orbit region.
  • [MeSH-minor] Adolescent. Adult. Cafe-au-Lait Spots / epidemiology. Child. Child, Preschool. Comorbidity. Female. Glioma / epidemiology. Humans. Infant. Infant, Newborn. Kyphosis / epidemiology. Male. Optic Nerve Diseases / epidemiology. Pigmentation Disorders / epidemiology. Poland / epidemiology. Retinal Neoplasms / epidemiology. Retinoblastoma / epidemiology. Visual Acuity


46. Chen L, Wang Y, Zhu XZ: [Pilomyxoid astrocytoma: a clinicopathologic study of three cases]. Zhonghua Bing Li Xue Za Zhi; 2006 Dec;35(12):727-30

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  • Two cases were located in the third ventricle, while the remaining case was located at the optic pathway.
  • [MeSH-major] Astrocytoma / pathology. Cerebral Ventricle Neoplasms / pathology. Optic Nerve Glioma / pathology. Third Ventricle / pathology
  • [MeSH-minor] Antigens, CD34 / metabolism. Child. Diagnosis, Differential. Female. Follow-Up Studies. Glial Fibrillary Acidic Protein / metabolism. Humans. Immunohistochemistry. Infant. Ki-67 Antigen / metabolism. Magnetic Resonance Imaging. Tomography, X-Ray Computed. Young Adult

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  • (PMID = 17374256.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Glial Fibrillary Acidic Protein; 0 / Ki-67 Antigen
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47. Lasky JL 3rd, Choe M, Nakano I: Cancer stem cells in pediatric brain tumors. Curr Stem Cell Res Ther; 2009 Dec;4(4):298-305
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  • Although recent studies have focused on molecular mechanisms that underlie the initiation and progression of adult glioblastoma multiforme (GBM), these tumors differ phenotypically and at a molecular level from pediatric brain tumors.
  • [MeSH-major] Brain Neoplasms / pathology. Ependymoma / pathology. Medulloblastoma / pathology. Neoplastic Stem Cells / pathology. Optic Nerve Glioma / pathology
  • [MeSH-minor] Adult Stem Cells / pathology. Biomarkers / metabolism. Cell Differentiation. Chemotherapy, Adjuvant. Child. Humans. Surgical Procedures, Operative


48. Scalzone M, Coccia P, Ruggiero A, Riccardi R: Neurofibromatosis type 1 clinical features and management. Pediatr Med Chir; 2009 Nov-Dec;31(6):246-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adolescent. Adult. Age Factors. Child. Child, Preschool. Genotype. Humans. Infant. Infant, Newborn. Magnetic Resonance Imaging. Optic Nerve Glioma / diagnosis. Patient Care Team. Phenotype

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  • (PMID = 20333883.001).
  • [ISSN] 0391-5387
  • [Journal-full-title] La Pediatria medica e chirurgica : Medical and surgical pediatrics
  • [ISO-abbreviation] Pediatr Med Chir
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Italy
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49. Ruivo J, Antunes JL: Maffucci syndrome associated with a pituitary adenoma and a probable brainstem tumor. J Neurosurg; 2009 Feb;110(2):363-8
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  • The authors present the first case of Maffucci syndrome associated with a pituitary adenoma and a probable brainstem glioma and review the literature concerning intracranial tumors related to this disease.
  • To the authors' knowledge, including the present case, only 7 cases of Maffucci syndrome associated with glioma and 7 cases associated with pituitary adenoma have been reported in the literature.
  • [MeSH-minor] Adult. Decompression, Surgical. Female. Humans. Nerve Compression Syndromes / diagnosis. Nerve Compression Syndromes / surgery. Optic Chiasm / pathology. Optic Nerve Diseases / diagnosis. Optic Nerve Diseases / surgery. Vision Disorders / diagnosis. Vision Disorders / etiology. Vision Disorders / surgery

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  • (PMID = 18976063.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 67
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50. Marchal JC, Civit T: Neurosurgical concepts and approaches for orbital tumours. Adv Tech Stand Neurosurg; 2006;31:73-117

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  • We have endeavoured, in this chapter, to highlight the specifically neurosurgical features of orbital tumours or, to be more precise, tumours affecting the posterior two thirds of the orbit and tumours originating in or intruding into the optic canal.
  • After recapitulating the main types of tumour (as well as those of most concern), we have also studied the different stages of surgery, namely approaches and reconstructions which we have illustrated at each stage by a tumour that, in our view, seemed emblematic of the problem in question: the lateral eyebrow approach for schwannoma and cavernous angioma, the transorbital subfrontal approach for optic nerve glioma, the pterional and orbital approaches for spheno-orbital meningioma, problems with reconstruction and with plexiform neurofibroma affecting the orbit and fibrous dysplasia of bone.
  • [MeSH-minor] Adult. Child. Humans

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  • (PMID = 16768304.001).
  • [ISSN] 0095-4829
  • [Journal-full-title] Advances and technical standards in neurosurgery
  • [ISO-abbreviation] Adv Tech Stand Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 80
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51. Składzień J, Tomik J, Wiatr M: [Primary benign orbital tumors in experience of the Department of Otolaryngology Jagiellonian University]. Przegl Lek; 2006;63(11):1210-2

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  • RESULTS: In all patients eyeball was preserved, even in 6 with optic nerve glioma.
  • Reccurent tumors were observed in 2 cases, diplopia in 15 patients and sight's lost in 8 (in 6 with optic nerve glioma).
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Hospitals, University. Humans. Infant. Middle Aged. Orbit / surgery. Orbit Evisceration / methods. Otolaryngology. Retrospective Studies. Treatment Outcome

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  • (PMID = 17348418.001).
  • [ISSN] 0033-2240
  • [Journal-full-title] Przegla̧d lekarski
  • [ISO-abbreviation] Prz. Lek.
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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52. Rizvi SA, Gupta Y, Gupta M: Surgical treatment and histopathological analysis of proptosis. Nepal J Ophthalmol; 2010 Jan-Jun;2(1):31-4
MedlinePlus Health Information. consumer health - Eye Cancer.

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  • Three cases of rhabdomyosarcoma, 3 cases of dermoid cyst and 1 case each of optic nerve glioma were found in pediatric age group.
  • The most common benign adult tumor found in our study was pleomorphic adenoma of the lacrimal gland {3 (20%)}.
  • [MeSH-minor] Adolescent. Adult. Aged. Biopsy. Child. Child, Preschool. Diagnosis, Differential. Humans. Infant. Infant, Newborn. Middle Aged. Retrospective Studies. Treatment Outcome. Young Adult

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  • (PMID = 21141324.001).
  • [ISSN] 2072-6805
  • [Journal-full-title] Nepalese journal of ophthalmology : a biannual peer-reviewed academic journal of the Nepal Ophthalmic Society : NEPJOPH
  • [ISO-abbreviation] Nepal J Ophthalmol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Nepal
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53. Ohtsuka K, Hashimoto M, Suzuki Y: A review of 244 orbital tumors in Japanese patients during a 21-year period: origins and locations. Jpn J Ophthalmol; 2005 Jan-Feb;49(1):49-55

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  • The common tumors were reactive lymphoid hyperplasia (22%) and malignant lymphoma (20%) in the extraconal area; cavernous hemangioma (25%), optic nerve glioma (14%), and optic nerve sheath meningioma (14%) in the intraconal area; and malignant lymphoma (40%) and pleomorphic adenoma (24%) in the lacrimal gland area.
  • In the 0- to 9-year-old patients, the most common tumors were dermoid cyst (26%), optic nerve glioma (11%), capillary hemangioma (11%), and hemorrhagic lymphangioma (11%).
  • [MeSH-minor] Adolescent. Adult. Age Distribution. Aged. Aged, 80 and over. Child. Child, Preschool. Female. Humans. Infant. Infant, Newborn. Japan. Male. Middle Aged

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  • (PMID = 15692775.001).
  • [ISSN] 0021-5155
  • [Journal-full-title] Japanese journal of ophthalmology
  • [ISO-abbreviation] Jpn. J. Ophthalmol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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54. Forte R, Cennamo G, Breve MA: Three-dimensional ultrasound of ophthalmic pathologies. Ophthalmologica; 2009;223(3):183-7
MedlinePlus Health Information. consumer health - Melanoma.

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  • RESULTS: Of the 20 eyes, an epiretinal membrane was present in 2 eyes, diabetic macular edema in 6, a macular hole in 2, a myopic posterior detachment in 2, myopic peripapillary detachment of the pigment epithelium in 1, choroidal melanoma in 4, optic nerve glioma in 1 case, carotidocavernous fistula in 1 and an intravitreal dislocation of an intraocular lens in 1 eye.
  • [MeSH-minor] Adult. Aged. Cross-Sectional Studies. Humans. Macular Edema / ultrasonography. Middle Aged. Young Adult

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  • [Copyright] Copyright 2009 S. Karger AG, Basel.
  • (PMID = 19182494.001).
  • [ISSN] 1423-0267
  • [Journal-full-title] Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde
  • [ISO-abbreviation] Ophthalmologica
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Switzerland
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55. Ohno K: [Continuous clinical management of patients with neurofibromatosis type 1]. Nihon Rinsho; 2010 Jan;68(1):131-5
Genetic Alliance. consumer health - Neurofibromatosis type 1.

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  • Serious complication during early childhood is rare but optic glioma, brain tumors or leukemia may appear.
  • Malignant peripheral nerve sheath tumors that arise from plexiform neurifibromas are a particularly devastating complication during middle age.
  • [MeSH-minor] Adolescent. Adult. Age Factors. Child. Child, Preschool. Gene Deletion. Genes, Neurofibromatosis 1. Humans. Infant. Infant, Newborn. Middle Aged. Young Adult

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  • (PMID = 20077805.001).
  • [ISSN] 0047-1852
  • [Journal-full-title] Nihon rinsho. Japanese journal of clinical medicine
  • [ISO-abbreviation] Nippon Rinsho
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 14
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56. Wimmer K: [Neurofibromatosis: the most frequent hereditary tumor predisposition syndrome]. Wien Med Wochenschr; 2005 Jun;155(11-12):273-80
Genetic Alliance. consumer health - TUMOR PREDISPOSITION SYNDROME.

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  • However, the disorder should not be underestimated as a "mere cosmetic problem", since NF1 patients are at increased risk to also develop malignant tumours, such as malignant peripheral nerve sheath tumours (MPNST), juvenile myelomonocytic leukaemia (JMML), optic glioma and pheochomocytoma.
  • Great advantages have been achieved in the monitoring and management of several NF1 complications, for instance in the treatment of tibia pseudarthrosis and optic gliomas.
  • [MeSH-minor] Adolescent. Adult. Child. Chromosome Aberrations. DNA Mutational Analysis. Disease Susceptibility. Genetic Counseling. Genetic Predisposition to Disease / genetics. Genetic Testing. Genotype. Heterozygote Detection. Humans. Neurofibromin 1 / genetics. Neurofibromin 2 / genetics. Phenotype. Risk

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  • (PMID = 16035388.001).
  • [ISSN] 0043-5341
  • [Journal-full-title] Wiener medizinische Wochenschrift (1946)
  • [ISO-abbreviation] Wien Med Wochenschr
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Austria
  • [Chemical-registry-number] 0 / Neurofibromin 1; 0 / Neurofibromin 2
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57. Romano LM, Gaspari M, Guagnini M: [Bilateral malignant astrocytoma of the optic nerve in the adult]. Neurologia; 2007 Jul-Aug;22(6):389-90
MedlinePlus Health Information. consumer health - MRI Scans.

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  • [Title] [Bilateral malignant astrocytoma of the optic nerve in the adult].
  • [Transliterated title] Astrocitoma óptico maligno bilateral del adulto.
  • [MeSH-major] Magnetic Resonance Imaging. Optic Nerve Glioma / radiography

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  • (PMID = 17610167.001).
  • [ISSN] 0213-4853
  • [Journal-full-title] Neurología (Barcelona, Spain)
  • [ISO-abbreviation] Neurologia
  • [Language] spa
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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