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Items 1 to 57 of about 57
1. Dokmak S, Cabral C, Couvelard A, Aussilhou B, Belghiti J, Sauvanet A: Pancreatic metastasis from nephroblastoma: an unusual entity. JOP; 2009;10(4):396-9
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  • [Title] Pancreatic metastasis from nephroblastoma: an unusual entity.
  • CONTEXT: Pancreatic metastasis from renal cell carcinoma is a well-known entity.
  • A nephroblastoma is a frequent childhood cancer but can also occur in adults.
  • A metastatic nephroblastoma mainly affects the lung and the liver.
  • Pancreatic metastases from a nephroblastoma are very rare.
  • CASE REPORT: We report an extremely rare case of pancreatic metastases in a 20-year-old man who had a right nephroblastoma resected at 9 years of age and liver metastases treated by right hepatectomy at 18 years of age.
  • Pathological examination confirmed pancreatic and liver metastases from a nephroblastoma composed of blastematous cells mixed with embryonic tubular structures without lymph node metastases.
  • CONCLUSION: This is probably the first case of pancreatic metastasis from a nephroblastoma reported in a living patient.
  • A nephroblastoma, like clear cell renal carcinoma, can be considered a possible etiology of pancreatic metastasis from a primary renal tumor.
  • [MeSH-major] Kidney Neoplasms / pathology. Pancreatic Neoplasms / secondary. Wilms Tumor / pathology
  • [MeSH-minor] Combined Modality Therapy. Drug Therapy / methods. Humans. Male. Pancreaticoduodenectomy / methods. Treatment Outcome. Young Adult

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  • (PMID = 19581742.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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2. Koizumi K, Mizusawa H, Oguchi T, Domen T, Kato H: [Adult Wilms' tumor mimicking adrenal tumor: case report]. Hinyokika Kiyo; 2008 Sep;54(9):603-6
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  • [Title] [Adult Wilms' tumor mimicking adrenal tumor: case report].
  • Computed tomography, magnetic resonance image and angiograpy demonstrated non-functioning adrenal tumor.
  • Right nephrectomy was performed, because the tumor adhered firmly to the upper pole of the right kidney.
  • The pathological diagnosis was nephroblastoma (nephroblastic type, complex subtype).
  • Postoperative chemotherapy was started for stage III Wilms' tumor.
  • In adult patients, postoperative chemotherapy for nephroblastoma is often interrupted due to side effects.
  • [MeSH-major] Kidney Neoplasms / diagnosis. Wilms Tumor / diagnosis
  • [MeSH-minor] Adrenal Gland Neoplasms. Adult. Antineoplastic Combined Chemotherapy Protocols / adverse effects. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Combined Modality Therapy. Dactinomycin / administration & dosage. Diagnosis, Differential. Diagnostic Imaging. Female. Humans. Nephrectomy. Vincristine / administration & dosage

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  • (PMID = 18975574.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 1CC1JFE158 / Dactinomycin; 5J49Q6B70F / Vincristine
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3. Bruder E, Moch H, Ehrlich D, Leuschner I, Harms D, Argani P, Briner J, Graf N, Selle B, Rufle A, Paulussen M, Koesters R: Wnt signaling pathway analysis in renal cell carcinoma in young patients. Mod Pathol; 2007 Dec;20(12):1217-29
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  • [Title] Wnt signaling pathway analysis in renal cell carcinoma in young patients.
  • Renal cell carcinomas in young patients constitute a morphologically and genetically heterogeneous group.
  • Twenty percent belong to the newly recognized Xp11.2 translocation-associated family and rare tumors arise from nephroblastoma.
  • Aberrant Wnt signaling through beta-catenin mutation has been implicated in nephroblastoma pathogenesis and has been found to synergize with WT1 mutations.
  • To characterize Wnt signaling activity in renal cell carcinomas in young patients, we gathered 34 tumors (three clear cell, ten Xp11.2 translocation associated, five papillary, two chromophobe, two collecting duct, one neuroblastoma associated, eight unclassified renal cell carcinomas, and three carcinomas combined with nephroblastoma) from patients less than 22 years.
  • Cytoplasmic beta-catenin accumulation was demonstrated in two papillary carcinomas, one neuroblastoma-associated carcinoma, and two carcinomas arising from nephroblastoma.
  • The pattern of gamma-catenin expression paralleled that of beta-catenin but its signal intensity was lower in 22, equal in 7, and stronger only in 1 tumor, respectively.
  • A WT1 mutation was found in the nephroblastoma component of a carcinoma arising from nephroblastoma.
  • These findings suggest Wnt signaling pathway activation only in a minority of renal cell carcinomas in young patients.
  • WT1 mutation in the nephroblastoma component of a mixed-type renal cell carcinoma provides direct evidence for clonal independence of nephroblastoma and carcinoma components in this exceptional tumor.
  • [MeSH-major] Carcinoma, Renal Cell / metabolism. Kidney Neoplasms / metabolism. Signal Transduction / physiology. Wnt Proteins / metabolism
  • [MeSH-minor] Adolescent. Adult. Base Sequence. Child. Child, Preschool. DNA Mutational Analysis. Female. Humans. Immunohistochemistry. Male. Molecular Sequence Data. Mutation. Polymerase Chain Reaction. beta Catenin / genetics. beta Catenin / metabolism. gamma Catenin / genetics. gamma Catenin / metabolism

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  • (PMID = 17873895.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Wnt Proteins; 0 / beta Catenin; 0 / gamma Catenin
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4. Gery S, Xie D, Yin D, Gabra H, Miller C, Wang H, Scott D, Yi WS, Popoviciu ML, Said JW, Koeffler HP: Ovarian carcinomas: CCN genes are aberrantly expressed and CCN1 promotes proliferation of these cells. Clin Cancer Res; 2005 Oct 15;11(20):7243-54
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  • PURPOSE: The connective tissue growth factor/cysteine-rich 61/nephroblastoma overexpressed (CCN) family consists of six matricellular proteins that are involved in various cellular functions, such as proliferation, development, and angiogenesis.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Animals. Apoptosis / drug effects. Apoptosis / genetics. Blotting, Northern. Blotting, Western. Carboplatin / pharmacology. Cell Line, Tumor. Cell Proliferation / drug effects. Cisplatin / pharmacology. Cysteine-Rich Protein 61. Epithelial Cells / metabolism. Epithelial Cells / pathology. Female. Gene Expression Regulation, Neoplastic / genetics. Humans. Immunohistochemistry. Mice. Mice, Nude. Middle Aged. Neoplasm Transplantation. Neoplasms, Experimental / genetics. Neoplasms, Experimental / metabolism. Neoplasms, Experimental / pathology. Protein Isoforms / genetics. Protein Isoforms / metabolism. RNA, Small Interfering / genetics. Reverse Transcriptase Polymerase Chain Reaction. Transfection. Transplantation, Heterologous

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  • (PMID = 16243794.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CYR61 protein, human; 0 / Cysteine-Rich Protein 61; 0 / Immediate-Early Proteins; 0 / Intercellular Signaling Peptides and Proteins; 0 / Protein Isoforms; 0 / RNA, Small Interfering; BG3F62OND5 / Carboplatin; Q20Q21Q62J / Cisplatin
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5. Bisceglia M, Ragazzi M, Galliani CA, Lastilla G, Rosai J: TTF-1 expression in nephroblastoma. Am J Surg Pathol; 2009 Mar;33(3):454-61
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  • [Title] TTF-1 expression in nephroblastoma.
  • The unexpected observation of nuclear immunoreactivity for thyroid transcription factor-1 (TTF-1) associated with an apparent lack of nuclear immunoreactivity for Wilms tumor-1 protein (WT1) in the pulmonary metastasis of a morphologically typical case of nephroblastoma affecting a 6.5-year-old male prompted us to examine the expression of these 2 markers (and CD56) in a series of 48 nephroblastomas, 5 adult metanephric adenomas, and 1 pediatric cystic nephroma.
  • It may reflect the embryonal nature of these tumors and may conceivably result-directly or indirectly-in interference with the transcriptional control of target genes and other molecular events in the pathway leading to the development of nephroblastoma.
  • [MeSH-major] Biomarkers, Tumor / analysis. Kidney Neoplasms / metabolism. Nuclear Proteins / biosynthesis. Transcription Factors / biosynthesis. Wilms Tumor / metabolism
  • [MeSH-minor] Adult. Antigens, CD56 / biosynthesis. Child. Child, Preschool. Female. Humans. Immunohistochemistry. Infant. Male. Middle Aged. Retrospective Studies. WT1 Proteins / biosynthesis

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  • (PMID = 19011567.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD56; 0 / Biomarkers, Tumor; 0 / Nuclear Proteins; 0 / Transcription Factors; 0 / WT1 Proteins; 0 / thyroid nuclear factor 1
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6. Papaioannou G, Sebire NJ, McHugh K: Imaging of the unusual pediatric 'blastomas'. Cancer Imaging; 2009;9:1-11
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  • The 'commoner' blastomas (neuroblastoma, nephroblastoma, hepatoblastoma, medulloblastoma) account for approximately 25% of solid tumors in the pediatric age range.
  • [MeSH-minor] Adolescent. Brain Neoplasms / diagnosis. Brain Neoplasms / pathology. Brain Neoplasms / radiography. Child. Child, Preschool. Chondroblastoma / pathology. Chondroblastoma / radiography. Female. Gonadoblastoma / radiography. Gonadoblastoma / ultrasonography. Hemangioblastoma / pathology. Hemangioblastoma / radiography. Humans. Infant. Infant, Newborn. Lipoma / diagnosis. Lipoma / pathology. Lipoma / radiography. Lipoma / ultrasonography. Male. Medulloblastoma / pathology. Medulloblastoma / radiography. Osteoblastoma / pathology. Osteoblastoma / radiography. Pancreatic Neoplasms / pathology. Pancreatic Neoplasms / radiography. Pancreatic Neoplasms / ultrasonography. Pineal Gland / pathology. Pineal Gland / radiography. Pinealoma / pathology. Pinealoma / radiography. Salivary Gland Neoplasms / radiography. Salivary Gland Neoplasms / ultrasonography. Thoracic Neoplasms / pathology. Thoracic Neoplasms / radiography. Young Adult

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  • [Cites] Radiology. 2000 Feb;214(2):476-82 [10671596.001]
  • [Cites] Gynecol Oncol. 1995 Jul;58(1):124-8 [7789879.001]
  • [Cites] Int J Pediatr Otorhinolaryngol. 2000 Jun 30;53(2):157-61 [10906522.001]
  • [Cites] J Bone Joint Surg Am. 2000 Aug;82-A(8):1140-5 [10954104.001]
  • [Cites] Pediatr Surg Int. 2000;16(5-6):458-61 [10955594.001]
  • [Cites] Diagn Cytopathol. 2000 Nov;23(5):348-50 [11074632.001]
  • [Cites] Br J Plast Surg. 2000 Dec;53(8):697-9 [11090328.001]
  • [Cites] Pediatr Surg Int. 2000;16(8):595-8 [11149404.001]
  • [Cites] Surg Today. 2001;31(5):438-42 [11381509.001]
  • [Cites] Pediatr Radiol. 2001 Jul;31(7):501-6 [11486805.001]
  • [Cites] Eur J Pediatr Surg. 2001 Oct;11(5):342-9 [11719876.001]
  • [Cites] J Neurooncol. 2001 Sep;54(3):239-49 [11767290.001]
  • [Cites] J Neurooncol. 2001 Sep;54(3):251-61 [11767291.001]
  • [Cites] Neuropathol Appl Neurobiol. 2002 Aug;28(4):257-82 [12175339.001]
  • [Cites] Top Magn Reson Imaging. 2002 Aug;13(4):219-29 [12409690.001]
  • [Cites] Clin Imaging. 1996 Jan-Mar;20(1):37-41 [8846307.001]
  • [Cites] Br J Neurosurg. 1996 Oct;10(5):507-11 [8922714.001]
  • [Cites] Neurosurg Rev. 1997;20(1):51-4 [9085288.001]
  • [Cites] AJNR Am J Neuroradiol. 1997 May;18(5):847-50 [9159361.001]
  • [Cites] Skeletal Radiol. 1999 Jan;28(1):33-40 [10068073.001]
  • [Cites] Am J Surg Pathol. 1999 Mar;23(3):342-8 [10078927.001]
  • [Cites] Am J Hum Genet. 1999 Apr;64(4):921-7 [10090875.001]
  • [Cites] Int J Urol. 1999 Mar;6(3):164-6 [10226831.001]
  • [Cites] Pediatr Radiol. 2004 Dec;34(12):1005-7 [15278323.001]
  • [Cites] Pancreas. 2005 Jan;30(1):87-90 [15632705.001]
  • [Cites] Cancer Genet Cytogenet. 2005 Mar;157(2):109-17 [15721631.001]
  • [Cites] Pediatr Surg Int. 2005 Mar;21(3):223-6 [15756566.001]
  • [Cites] Pediatr Radiol. 2005 Apr;35(4):358-73; quiz 457 [15536562.001]
  • [Cites] Pediatr Radiol. 2005 Apr;35(4):387-91 [15657793.001]
  • [Cites] J Bone Joint Surg Am. 2005 Jun;87(6):1358-62 [15930549.001]
  • [Cites] Radiographics. 2006 Jul-Aug;26(4):1211-38 [16844942.001]
  • [Cites] Pediatr Radiol. 2006 Aug;36(8):851-6 [16775739.001]
  • [Cites] Urology. 2007 Aug;70(2):372.e1-2 [17826513.001]
  • [Cites] Arq Neuropsiquiatr. 2008 Mar;66(1):64-8 [18392417.001]
  • [Cites] J Orthop Surg (Hong Kong). 2008 Apr;16(1):84-7 [18453666.001]
  • [Cites] J Pediatr Orthop. 2008 Jul-Aug;28(5):555-60 [18580372.001]
  • [Cites] Eur J Surg Oncol. 2002 Dec;28(8):869-74 [12477480.001]
  • [Cites] Cancer Cell. 2002 Dec;2(6):447-50 [12498713.001]
  • [Cites] Skeletal Radiol. 2003 Feb;32(2):66-71 [12589483.001]
  • [Cites] Neuroradiology. 2003 Apr;45(4):212-9 [12687303.001]
  • [Cites] Spinal Cord. 2003 Jun;41(6):359-64 [12746743.001]
  • [Cites] Cancer Genet Cytogenet. 2003 Jun;143(2):174-7 [12781454.001]
  • [Cites] Am J Phys Med Rehabil. 2003 Oct;82(10):820-3 [14508414.001]
  • [Cites] Acta Orthop Belg. 2003 Oct;69(5):467-72 [14648960.001]
  • [Cites] Ann Diagn Pathol. 2003 Dec;7(6):387-98 [15018124.001]
  • [Cites] Cancer Genet Cytogenet. 2004 Feb;149(1):58-62 [15104284.001]
  • [Cites] J Pediatr Surg. 2004 Jul;39(7):1003-13 [15213888.001]
  • [Cites] Clin Oncol (R Coll Radiol). 2004 Jun;16(4):244-7 [15214647.001]
  • [Cites] Cancer. 2004 Sep 15;101(6):1445-54 [15368333.001]
  • [Cites] Cancer. 1973 Aug;32(2):482-92 [4353020.001]
  • [Cites] Pediatr Pulmonol. 1992 Dec;14(4):222-32 [1336597.001]
  • [Cites] AJR Am J Roentgenol. 2000 Jun;174(6):1639-41 [10845499.001]
  • (PMID = 19237343.001).
  • [ISSN] 1470-7330
  • [Journal-full-title] Cancer imaging : the official publication of the International Cancer Imaging Society
  • [ISO-abbreviation] Cancer Imaging
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 52
  • [Other-IDs] NLM/ PMC2651735
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7. Grieco V, Riccardi E, Belotti S, Scanziani E: Immunohistochemical study of porcine nephroblastoma. J Comp Pathol; 2006 Feb-Apr;134(2-3):143-51
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  • [Title] Immunohistochemical study of porcine nephroblastoma.
  • Nephroblastoma, a relatively common renal neoplasm of young swine, represents the animal counterpart of Wilms' tumour of children.
  • The kidney originates from mesenchymal blastema, which changes to epithelium, losing VIM and acquiring CK expression.
  • In the adult mammalian kidney, CK 19 is expressed only by the parietal epithelium of Bowman's capsule and the distal tubules.
  • This finding, together with the co-expression of VIM detected in some tubules, demonstrates the embryonic origin of nephroblastoma.
  • [MeSH-major] Immunoenzyme Techniques / veterinary. Kidney Neoplasms / veterinary. Swine Diseases / pathology. Wilms Tumor / veterinary
  • [MeSH-minor] Animals. Biomarkers, Tumor / metabolism. Kidney / metabolism. Kidney / pathology. Mesoderm / metabolism. Mesoderm / pathology. Mitotic Index. Swine. Vimentin / metabolism

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  • (PMID = 16540114.001).
  • [ISSN] 0021-9975
  • [Journal-full-title] Journal of comparative pathology
  • [ISO-abbreviation] J. Comp. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Vimentin
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8. Nonaka D, Tang Y, Chiriboga L, Rivera M, Ghossein R: Diagnostic utility of thyroid transcription factors Pax8 and TTF-2 (FoxE1) in thyroid epithelial neoplasms. Mod Pathol; 2008 Feb;21(2):192-200
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  • Pax8 was expressed in renal tubules, fallopian tubes, ovarian inclusion cysts, and lymphoid follicles as well as renal carcinoma, nephroblastoma, seminoma, and ovarian carcinoma, but not in normal tissue and carcinomas of the lung.
  • [MeSH-major] Adenocarcinoma / metabolism. Adenoma / metabolism. Adenosine Triphosphatases / metabolism. Biomarkers, Tumor / metabolism. Carcinoma, Papillary / metabolism. DNA-Binding Proteins / metabolism. Paired Box Transcription Factors / metabolism. Thyroid Neoplasms / metabolism. Transcription Factors / metabolism
  • [MeSH-minor] Adenocarcinoma, Follicular / diagnosis. Adenocarcinoma, Follicular / metabolism. Adolescent. Adult. Aged. Aged, 80 and over. Calcitonin / metabolism. Carcinoma / diagnosis. Carcinoma / metabolism. Carcinoma, Medullary / diagnosis. Carcinoma, Medullary / metabolism. Female. Fluorescent Antibody Technique, Indirect. Humans. Hyperplasia. Immunoenzyme Techniques. Male. Middle Aged. Thyroid Gland / metabolism. Thyroid Gland / pathology. Tissue Array Analysis

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  • (PMID = 18084247.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA-Binding Proteins; 0 / PAX8 protein, human; 0 / Paired Box Transcription Factors; 0 / Transcription Factors; 9007-12-9 / Calcitonin; EC 3.6.1.- / Adenosine Triphosphatases; EC 3.6.1.- / TTF2 protein, human
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9. Llarena Ibarguren R, Villafruela Mateos A, Azurmendi Arin I, García Fernández J, Olano Grasa I, Padilla Nieva J, Pertusa Peña C: [Nephroblastoma or Wilms tumor. Adult presentation. Report of two cases]. Arch Esp Urol; 2007 Jun;60(5):539-44
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  • [Title] [Nephroblastoma or Wilms tumor. Adult presentation. Report of two cases].
  • [Transliterated title] Nefroblastoma o tumor de Wilms. Presentación en adultos. Estudio de dos casos.
  • OBJECTIVES: To present to new cases of nephroblastoma or Wilms tumor diagnosed in adult age.
  • METHODS: The first case we report is a 16-year-old female with the diagnosis of stage I nephroblastoma after radical nephrectomy for a right renal mass.
  • The second case is a 33-year-old female with the diagnosis of nephroblastoma after percutaneous biopsy of a right renal mass.
  • CONCLUSIONS: This type of tumor typical of childhood is extremely rare in adult age, and despite worse survivals and more aggressiveness are described, they may be treated with the same protocols used in children, following any of the two big co-operative groups: American NWTS or European SIOP.
  • [MeSH-major] Kidney Neoplasms. Wilms Tumor
  • [MeSH-minor] Adolescent. Adult. Female. Humans

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  • (PMID = 17718208.001).
  • [ISSN] 0004-0614
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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10. Eckschlager T, Radvanska J, Slaby K, Prusa R, Hochova I, Radvansky J: Changes of blood count, lymphocyte subpopulations and immunoglobulin levels in nephroblastoma long term survivors. Neoplasma; 2009;56(1):9-12
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  • [Title] Changes of blood count, lymphocyte subpopulations and immunoglobulin levels in nephroblastoma long term survivors.
  • The aim of this study was to investigate the frequency of blood count, lymphocyte subpopulations, and immunoglobulin levels alterations in a group of healthy nephroblastoma long-term survivors.
  • The group included 122 nephroblastoma longterm survivors who were at least five years post anticancer therapy and free of any sign of recurrence The proportion of lymphocyte subpopulations was analyzed by flow cytometry using antibodies anti CD45 FITC/CD14 PE, anti CD3 FITC/ CD16+CD56 PE, anti CD4 FITC/ CD8 PE and anti CD20 FITC.
  • Key words: nephroblastoma long-term survivors, blood count, lymphocyte subpopulations, immunoglobulin G, A, M serum levels.
  • [MeSH-major] Kidney Neoplasms / blood. Kidney Neoplasms / immunology. Wilms Tumor / blood. Wilms Tumor / immunology
  • [MeSH-minor] Adolescent. Adult. Blood Cell Count. Child. Female. Flow Cytometry. Humans. Immunoglobulins / blood. Lymphocyte Subsets. Male. Survivors

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  • (PMID = 19152239.001).
  • [ISSN] 0028-2685
  • [Journal-full-title] Neoplasma
  • [ISO-abbreviation] Neoplasma
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Slovakia
  • [Chemical-registry-number] 0 / Immunoglobulins
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11. Szavay P, Luithle T, Graf N, Furtwängler R, Fuchs J: Primary hepatic metastases in nephroblastoma--a report of the SIOP/GPOH Study. J Pediatr Surg; 2006 Jan;41(1):168-72; discussion 168-72
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  • [Title] Primary hepatic metastases in nephroblastoma--a report of the SIOP/GPOH Study.
  • PURPOSE: Remarkable progress could be achieved in the treatment of nephroblastoma within the last decades.
  • In all children with Wilms' tumor, 5-year overall survival rate reaches more than 90% in the SIOP/GPOH Study Group.
  • Despite this fact, there is a small group of patients who have tumor lesions in the liver primarily representing a challenge in treatment.
  • Our report suggests that Wilms' tumor complicated by metastases of the liver primarily has a less favorable outcome.
  • [MeSH-major] Kidney Neoplasms / pathology. Liver Neoplasms / secondary. Nephrectomy. Wilms Tumor / secondary
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Combined Modality Therapy. Female. Humans. Infant. Male. Prognosis. Survival Analysis

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  • (PMID = 16410128.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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12. Fuchs J, Szavay P, Luithle T, Furtwängler R, Graf N: Surgical implications for liver metastases in nephroblastoma--data from the SIOP/GPOH study. Surg Oncol; 2008 Jul;17(1):33-40
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  • [Title] Surgical implications for liver metastases in nephroblastoma--data from the SIOP/GPOH study.
  • BACKGROUND: In children with Wilms' tumor, the 5-year overall survival rate is over 90% in the SIOP/GPOH study group.
  • However, a small group of patients have tumor lesions in the liver at the time of initial diagnosis or as a recurrence.
  • In 16 children who had a recurrence of a nephroblastoma in the liver (group II), median age at diagnosis was 4.62 years (1.84-31.08 years) with 9 males and 7 females.
  • CONCLUSION: This report suggests that when complicated by metastases of the liver, Wilms' tumor has a less favorable outcome.
  • [MeSH-major] Hepatectomy / methods. Kidney Neoplasms / surgery. Liver Neoplasms / surgery. Nephrectomy / methods. Wilms Tumor / surgery
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Female. Follow-Up Studies. Germany / epidemiology. Humans. Incidence. Infant. Male. Neoplasm Recurrence, Local / epidemiology. Prognosis. Prospective Studies. Survival Rate. Time Factors

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  • (PMID = 17935976.001).
  • [ISSN] 0960-7404
  • [Journal-full-title] Surgical oncology
  • [ISO-abbreviation] Surg Oncol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Netherlands
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13. Radvanský J, Slabý K, Radvanská J, Malis J, Eckschalger T, Sulc J, Safárová M, Kolský A, Procházka M, Gilík J: [Late effect of treatment of nephroblastoma in patients treated in 1980-2001 in a single centre]. Klin Onkol; 2010;23(4):245-55
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  • [Title] [Late effect of treatment of nephroblastoma in patients treated in 1980-2001 in a single centre].
  • BACKGROUNDS: The aim of the study was to describe the late effects in a cohort of patients in long-term remission (> 5 years from end of treatment) diagnosed and treated for nephroblastoma at the single paediatric centre during 1980- 2001.
  • PATIENTS AND METHODS: 151 patients were examined for renal function, lipid profile, sonography, echocardiography, exercise capacity and postural status.
  • It should include clinical examination, kidney function and blood pressure monitoring, sonographic and echocardiography examination, long-term physiotherapeutic care and prevention of cardiovascular diseases.
  • [MeSH-major] Kidney Neoplasms / therapy. Wilms Tumor / therapy
  • [MeSH-minor] Adolescent. Adult. Antineoplastic Agents / adverse effects. Blood Pressure. Child. Child, Preschool. Echocardiography. Female. Follow-Up Studies. Humans. Infant. Kidney / physiology. Lipids / blood. Male. Physical Fitness. Quality of Life. Remission Induction. Young Adult

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  • (PMID = 20806823.001).
  • [ISSN] 0862-495X
  • [Journal-full-title] Klinická onkologie : casopis Ceské a Slovenské onkologické spolecnosti
  • [ISO-abbreviation] Klin Onkol
  • [Language] cze
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Czech Republic
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Lipids
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14. Karim ME, Momen MA, Akhter S, Haque Z, Islam T, Haque MM, Hossain M: Wilms tumor in adult. Mymensingh Med J; 2010 Apr;19(2):299-302
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  • [Title] Wilms tumor in adult.
  • Wilms Tumor (WT) is a very rare malignancy in adults representing 1% of all renal neoplasms.
  • It is however the most common renal tumor of children and adult patients are treated like pediatric cases.
  • Bilateral tumors occur in 5% of adult cases.
  • As clinical presentation of WT is similar to that of renal cell carcinoma (RCC), it tends to be an unsuspected pathological diagnosis in most cases.
  • The diagnosis of the tumor needs positive sonographic and computed tomography (CT) findings with histopathological confirmation.
  • Prognosis of adult WT is relatively poor and resistant to chemotherapy.
  • We present a case of wilms tumor in a 68 years old male patient with right sided non tender abdominal mass and occasional flank pain.
  • The patient was normotensive but hematuric and radiological findings suggested right renal mass with enlarged lymph node and histopathological analysis revealed nephroblastoma associated with lymph node metastases.

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  • (PMID = 20395930.001).
  • [ISSN] 1022-4742
  • [Journal-full-title] Mymensingh medical journal : MMJ
  • [ISO-abbreviation] Mymensingh Med J
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Bangladesh
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15. Okasho K, Nishiyama H, Watanabe J, Soda T, Mikami Y, Koyama T, Kamoto T, Ogawa O: Adult wilms tumor in the renal pelvis: case report with review of the literature. Urology; 2008 Nov;72(5):1185.e5-7
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  • [Title] Adult wilms tumor in the renal pelvis: case report with review of the literature.
  • Retroperitoneoscopic nephroureterectomy was performed because of a clinical diagnosis of renal pelvic carcinoma.
  • Pathologic examination led to a final diagnosis of an adult Wilms tumor arising from the renal pelvis.
  • This is the first report of a Wilms tumor in the renal pelvis of an adult patient.
  • [MeSH-major] Kidney Neoplasms / diagnosis. Kidney Neoplasms / surgery. Kidney Pelvis. Wilms Tumor / diagnosis. Wilms Tumor / surgery

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  • (PMID = 18329072.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 14
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16. Schuck A, Hamelmann V, Brämswig JH, Könemann S, Rübe C, Hesselmann S, Riesenbeck D, Horst E, Bölling T, Paulussen M, Jürgens H, Willich N: Ovarian function following pelvic irradiation in prepubertal and pubertal girls and young adult women. Strahlenther Onkol; 2005 Aug;181(8):534-9
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  • [Title] Ovarian function following pelvic irradiation in prepubertal and pubertal girls and young adult women.
  • PURPOSE: To analyze the effect of pelvic radiotherapy on ovarian function in prepubertal and pubertal girls and young adult women.
  • The main tumor types were Hodgkin's disease (38%), Ewing's sarcoma (20%) and nephroblastoma (11%).
  • [MeSH-minor] Adolescent. Adult. Age Factors. Bone Neoplasms / radiotherapy. Chi-Square Distribution. Child. Child, Preschool. Dose Fractionation. Female. Follow-Up Studies. Hodgkin Disease / radiotherapy. Humans. Infant. Kidney Neoplasms / radiotherapy. Menarche. Pregnancy. Radiotherapy Dosage. Retrospective Studies. Sarcoma, Ewing / radiotherapy. Surveys and Questionnaires. Time Factors. Wilms Tumor / radiotherapy

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  • (PMID = 16044222.001).
  • [ISSN] 0179-7158
  • [Journal-full-title] Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]
  • [ISO-abbreviation] Strahlenther Onkol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
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17. Rodrigues FA, Ribeiro EC, Maroccolo Filho R, Silva EA, Diaz FA: Adult Wilms tumor during gestational period. Urology; 2009 Apr;73(4):929.e1-2
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  • [Title] Adult Wilms tumor during gestational period.
  • Magnetic resonance imaging showed a solid left renal mass.
  • The patient had a radical nephrectomy during the 20th week gestation and the diagnosis was nephroblastoma.
  • Based on the excellent results achieved while treating children with Wilms' tumor using surgery, chemotherapy and radiotherapy, adults with the same disease should be treated similarly.
  • [MeSH-major] Kidney Neoplasms. Pregnancy Complications, Neoplastic. Wilms Tumor
  • [MeSH-minor] Adolescent. Female. Humans. Kidney / injuries. Pregnancy

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  • (PMID = 18722653.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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18. Martínez Mansur R, Piana M, Codone J, Díez M, Elizalde F, Reyes E, Villeta M, Lioy Lupis M, Solano F, Serrano A, Proto J, Sicher R: [Wilms tumor in an adult patient: case report]. Arch Esp Urol; 2006 Jul-Aug;59(6):632-4
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  • [Title] [Wilms tumor in an adult patient: case report].
  • [Transliterated title] Tumor de Wilms en paciente adulto presentación de un caso.
  • Nephroblastoma or Wilms tumor is the most common renal neoplasia in children, representing 1/5 of the malignant tumors in this group.
  • Nevertheless, the incidence of such tumor in adults is much rarer with less than 250 cases reported.
  • Currently, the therapeutic options derive from the National Wilms Tumor Study (NWTS).
  • [MeSH-major] Kidney Neoplasms / diagnosis. Wilms Tumor / diagnosis

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  • (PMID = 16933494.001).
  • [ISSN] 0004-0614
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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19. Hsiao HL, Chang TH, Wu WJ, Huang CH: Adult Wilms' tumor with hypospadias and cryptorchidism: a case report. Kaohsiung J Med Sci; 2007 Nov;23(11):584-9
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  • [Title] Adult Wilms' tumor with hypospadias and cryptorchidism: a case report.
  • Abdominal ultrasonography and imaging studies showed a left renal mass.
  • Radical nephrectomy was performed on the patient and the pathology report revealed Wilms' tumor (nephroblastoma).
  • The patient underwent chemotherapy after surgery and no tumor recurrence was noted after 8 months of regular follow-up.
  • [MeSH-major] Cryptorchidism / complications. Hypospadias / complications. Kidney Neoplasms / complications. Wilms Tumor / complications

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  • (PMID = 18055308.001).
  • [ISSN] 1607-551X
  • [Journal-full-title] The Kaohsiung journal of medical sciences
  • [ISO-abbreviation] Kaohsiung J. Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
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20. Gellhaus A, Schmidt M, Dunk C, Lye SJ, Kimmig R, Winterhager E: Decreased expression of the angiogenic regulators CYR61 (CCN1) and NOV (CCN3) in human placenta is associated with pre-eclampsia. Mol Hum Reprod; 2006 Jun;12(6):389-99
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  • Here, we focused on the expressions of cysteine-rich 61 (CYR61, CCN1) and nephroblastoma overexpressed (NOV, CCN3), members of the CCN family of angiogenic regulators, in human placenta during normal pregnancy compared with pre-eclamptic and HELLP placentae using quantitative RT-PCR, western blotting and immunocytochemistry.
  • [MeSH-minor] Adult. Blotting, Western. Connective Tissue Growth Factor. Cysteine-Rich Protein 61. Female. HELLP Syndrome / genetics. HELLP Syndrome / metabolism. Humans. Immunohistochemistry. Microscopy, Fluorescence. Nephroblastoma Overexpressed Protein. Placenta / metabolism. Placenta / pathology. Pregnancy. RNA, Messenger / genetics. RNA, Messenger / metabolism. Reverse Transcriptase Polymerase Chain Reaction

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  • (PMID = 16675545.001).
  • [ISSN] 1360-9947
  • [Journal-full-title] Molecular human reproduction
  • [ISO-abbreviation] Mol. Hum. Reprod.
  • [Language] eng
  • [Grant] United States / NICHD NIH HHS / HD / R01 HD42558-01
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / CTGF protein, human; 0 / CYR61 protein, human; 0 / Cysteine-Rich Protein 61; 0 / Immediate-Early Proteins; 0 / Intercellular Signaling Peptides and Proteins; 0 / NOV protein, human; 0 / Nephroblastoma Overexpressed Protein; 0 / RNA, Messenger; 139568-91-5 / Connective Tissue Growth Factor
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21. MacKay GC, Howells J, Poon FW: Colobronchial fistula: a late complication of childhood radiotherapy. Br J Radiol; 2006 Feb;79(938):170-2
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  • We present the case of a colobronchial fistula in a 41-year-old man who underwent radiotherapy for nephroblastoma as an infant.
  • [MeSH-minor] Adult. Barium Sulfate. Contrast Media. Humans. Kidney Neoplasms / radiotherapy. Male. Wilms Tumor / radiotherapy

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  • (PMID = 16489201.001).
  • [ISSN] 0007-1285
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Contrast Media; 25BB7EKE2E / Barium Sulfate
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22. Maurer T, Zorn C, Klein E, Weirich G, Beer AJ, Gschwend JE, Zantl N: Multimodal tumor therapy in a 31-year-old pregnant woman with Wilms tumor. Urol Int; 2009;83(3):364-7
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  • [Title] Multimodal tumor therapy in a 31-year-old pregnant woman with Wilms tumor.
  • Wilms tumor, or nephroblastoma, is the most common malignant tumor of the urinary tract in children, but is rarely found in adults.
  • Here, we report the first case of a female patient with a Wilms tumor, diagnosed during pregnancy, who underwent radical nephrectomy and adjuvant chemotherapy before and after delivering a healthy child.
  • [MeSH-major] Kidney Neoplasms / drug therapy. Kidney Neoplasms / surgery. Pregnancy Complications, Neoplastic / drug therapy. Pregnancy Complications, Neoplastic / surgery. Wilms Tumor / drug therapy. Wilms Tumor / surgery
  • [MeSH-minor] Adult. Combined Modality Therapy. Female. Humans. Pregnancy

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  • (PMID = 19829043.001).
  • [ISSN] 1423-0399
  • [Journal-full-title] Urologia internationalis
  • [ISO-abbreviation] Urol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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23. Lucas S, Reindl T, Henze G, Kurtz A, Sakuma S, Driever PH: Increased midkine serum levels in pediatric embryonal tumor patients. J Pediatr Hematol Oncol; 2009 Oct;31(10):713-7

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  • [Title] Increased midkine serum levels in pediatric embryonal tumor patients.
  • Serum levels of midkine (MK), a heparin-binding growth factor, are elevated in adult cancer patients.
  • We analyzed sera of pediatric tumor patients in comparison to a large number of children and adolescents without malignant disease.
  • MK was studied in sera of 152 noncancer patients and 29 embryonal tumor patients (14 nephroblastoma, 10 neuroblastoma, and 5 rhabdomyosarcoma) using an enzyme-linked immunosorbent assay.
  • MK serum levels were significantly higher in tumor patients (median 0.621 ng/mL) than in noncancer patients.
  • About 86% of tumor patients were identified using a cut-off value of 0.176 ng/mL.
  • MK values did neither correlate with tumor size nor with stage or histology, but decreased in half of the nephroblastoma patients after chemotherapy and surgery.
  • [MeSH-minor] Adolescent. Biomarkers / blood. Case-Control Studies. Child. Child, Preschool. Cytokines / blood. Enzyme-Linked Immunosorbent Assay. Female. Humans. Infant. Male. Neuroblastoma / blood. Neuroblastoma / diagnosis. Neuroblastoma / therapy. Rhabdomyosarcoma / blood. Rhabdomyosarcoma / diagnosis. Rhabdomyosarcoma / therapy. Wilms Tumor / blood. Wilms Tumor / diagnosis. Wilms Tumor / therapy. Young Adult

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  • (PMID = 19727009.001).
  • [ISSN] 1536-3678
  • [Journal-full-title] Journal of pediatric hematology/oncology
  • [ISO-abbreviation] J. Pediatr. Hematol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Cytokines; 0 / MDK protein, human; 0 / Nerve Growth Factors; 137497-38-2 / midkine
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24. Pasmant E, Ortonne N, Rittié L, Laurendeau I, Lévy P, Lazar V, Parfait B, Leroy K, Dessen P, Valeyrie-Allanore L, Perbal B, Wolkenstein P, Vidaud M, Vidaud D, Bièche I: Differential expression of CCN1/CYR61, CCN3/NOV, CCN4/WISP1, and CCN5/WISP2 in neurofibromatosis type 1 tumorigenesis. J Neuropathol Exp Neurol; 2010 Jan;69(1):60-9
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  • Several CCN gene family members were dysregulated in neurofibromatosis type 1 tumorigenesis; the angiogenic gene CCN1/CYR61 was specifically upregulated in the plexiform neurofibromas; CCN4/WISP1 was upregulated, and CCN3/NOV and CCN5/WISP2 were downregulated in paired comparisons of plexiform neurofibroma and malignant peripheral nerve sheath tumor from the same patients.
  • [MeSH-minor] Adolescent. Adult. CCN Intercellular Signaling Proteins. Carcinogenicity Tests / methods. Cell Differentiation / genetics. Cells, Cultured. Cysteine-Rich Protein 61 / genetics. Cysteine-Rich Protein 61 / metabolism. Female. Gene Expression Profiling / methods. Humans. Intracellular Signaling Peptides and Proteins / genetics. Intracellular Signaling Peptides and Proteins / metabolism. Male. Middle Aged. Nephroblastoma Overexpressed Protein / genetics. Nephroblastoma Overexpressed Protein / metabolism. Oligonucleotide Array Sequence Analysis / methods. Proto-Oncogene Proteins / genetics. Proto-Oncogene Proteins / metabolism. RNA, Messenger / metabolism. Repressor Proteins. Schwann Cells / physiology. Statistics, Nonparametric. Transcription Factors / genetics. Transcription Factors / metabolism. Young Adult

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  • (PMID = 20010302.001).
  • [ISSN] 1554-6578
  • [Journal-full-title] Journal of neuropathology and experimental neurology
  • [ISO-abbreviation] J. Neuropathol. Exp. Neurol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CCN Intercellular Signaling Proteins; 0 / CYR61 protein, human; 0 / Cysteine-Rich Protein 61; 0 / Intercellular Signaling Peptides and Proteins; 0 / Intracellular Signaling Peptides and Proteins; 0 / NOV protein, human; 0 / Nephroblastoma Overexpressed Protein; 0 / Proto-Oncogene Proteins; 0 / RNA, Messenger; 0 / Repressor Proteins; 0 / Transcription Factors; 0 / WISP1 protein, human; 0 / WISP2 protein, human
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25. Tsukamoto Y, Namikawa T, Tatesaki R, Kotani T, Tanaka H: Expression and adhesive activity of SC1, an Ig superfamily cell adhesion molecule, in sporadic nephroblastomas of chicken. Oncol Rep; 2006 Jan;15(1):137-41
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  • Western blot analysis showed SC1 to be recognized as approximately 100 kDa and enriched in embryonic metanephros with a lower level in the adult kidney, while it was overexpressed in nephroblastomas.
  • In contrast, it had almost completely disappeared in the adult kidney; parts of the distal convoluted and intermediated tubules, collecting ducts, and Bowman's capsule slightly expressed SC1.
  • In all 32 cases of nephroblastoma, SC1 was overexpressed in most characteristic components in tumors such as neoplastic epithelia with various types of differentiation, blastemal cell condensations, and glomeruloid bodies.
  • Primary culture cells from a nephroblastoma expressed SC1 on the cell surface, whereas cells from the adult kidney showed only weak expression.
  • A cell aggregation assay revealed that the dissociated cells from a nephroblastoma have strong aggregation activity, which was inhibited by anti-SC1 antibody.
  • In contrast, the self-aggregation of adult chicken kidney cells was weaker than that of the tumor and not inhibited by the antibody.
  • These findings suggest that the expression of SC1 might play a potential role in both the structural formation of nephroblastomas, based on its adhesive activity, and normal renal development.
  • [MeSH-major] Activated-Leukocyte Cell Adhesion Molecule / metabolism. Chickens. Kidney Neoplasms / veterinary. Poultry Diseases / metabolism. Wilms Tumor / veterinary
  • [MeSH-minor] Animals. Cell Adhesion. Immunoglobulins / immunology. Immunohistochemistry. Kidney / chemistry. Kidney / metabolism. Kidney / pathology

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  • (PMID = 16328046.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Activated-Leukocyte Cell Adhesion Molecule; 0 / Immunoglobulins
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26. Benesch M, Windelberg M, Sauseng W, Witt V, Fleischhack G, Lackner H, Gadner H, Bode U, Urban C: Compassionate use of bevacizumab (Avastin) in children and young adults with refractory or recurrent solid tumors. Ann Oncol; 2008 Apr;19(4):807-13
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  • PATIENTS AND METHODS: Fifteen patients (male: n = 8; female: n = 7; median age, 14.6 years) received bevacizumab for recurrent or progressive solid tumors (carcinoma: n = 3; neuroblastoma: n = 2; astrocytoma grade III: n = 2; rhabdomyosarcoma: n = 2; nephroblastoma: n = 2; benign vascular tumors: n = 2; synovial sarcoma: n = 1; and malignant hemangiopericytoma: n = 1) on a compassionate basis.

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  • (PMID = 18056650.001).
  • [ISSN] 1569-8041
  • [Journal-full-title] Annals of oncology : official journal of the European Society for Medical Oncology
  • [ISO-abbreviation] Ann. Oncol.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Angiogenesis Inhibitors; 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 2S9ZZM9Q9V / Bevacizumab
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27. Singh S, Gupta R, Nigam S, Khurana N, Aggarwal SK, Chaturvedi KU, Mandal AK: Clinico-pathological profile of 22 cases of cystic renal dysplasia. Indian J Pathol Microbiol; 2007 Jan;50(1):6-10
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  • [Title] Clinico-pathological profile of 22 cases of cystic renal dysplasia.
  • Renal dysplasia is one of the major renal developmental anomaly characterized by abnormal structural organization and development of metanephric elements.
  • The kidney may be multicystic, aplastic, hypoplastic or duplex.
  • We studied 22 cases of cystic renal dysplasia diagnosed over a period often years to identify the spectrum of morphological changes in dysplastic kidney, with special emphasis on mesenchymal changes.
  • One case was a 21-year-old adult, which is a rare age at presentation.
  • One of our patients had contra-lateral ureteric stenosis, a rare anomaly reported with renal dysplasia.
  • As cystic renal dysplasia is not a hereditary disease, it must be differentiated from polycystic kidney disease.
  • Other differential diagnoses are cystic nephroma and cystic partially differentiated nephroblastoma.
  • Histopathological examination is the final diagnostic tool since radiological features alone may not be sufficient to exclude other cystic renal lesions.
  • Cartilage may not be seen in all cases of renal dysplasia.
  • [MeSH-major] Kidney / pathology. Multicystic Dysplastic Kidney / pathology
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Diagnosis, Differential. Epithelium / pathology. Female. Histocytochemistry. Humans. Infant. Infant, Newborn. Male. Mesoderm / pathology. Polycystic Kidney Diseases / diagnosis

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  • (PMID = 17474245.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
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28. Shimakage M, Kawahara K, Harada S, Sasagawa T, Shinka T, Oka T: Expression of Epstein-Barr virus in renal cell carcinoma. Oncol Rep; 2007 Jul;18(1):41-6
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  • [Title] Expression of Epstein-Barr virus in renal cell carcinoma.
  • There have been few studies regarding the etiology of renal cell carcinoma.
  • To examine the possible involvement of Epstein-Barr virus (EBV) in this disease, 9 renal cell carcinoma (RCC), 2 nephroblastoma (Wilms' tumor) and 2 RCC cell lines were subjected to mRNA in situ hybridization and indirect immunofluorescence staining.
  • EBV infected all the RCC and nephroblastoma irrespective of the histological or clinical stage.
  • These results suggest that the expression of EBV may be involved in the pathogenesis of RCC and nephroblastoma.
  • [MeSH-major] Carcinoma, Papillary / virology. Carcinoma, Renal Cell / virology. Epstein-Barr Virus Infections / virology. Kidney Neoplasms / virology. Urinary Bladder Neoplasms / virology. Wilms Tumor / virology
  • [MeSH-minor] Adult. Aged. Child, Preschool. Epstein-Barr Virus Nuclear Antigens / genetics. Epstein-Barr Virus Nuclear Antigens / metabolism. Female. Fluorescent Antibody Technique. Fluorescent Antibody Technique, Indirect. Herpesvirus 4, Human / isolation & purification. Humans. In Situ Hybridization. Infant. Male. Middle Aged. Polymerase Chain Reaction. RNA Probes. RNA, Messenger / genetics. RNA, Messenger / metabolism. RNA, Viral / analysis. Reverse Transcriptase Polymerase Chain Reaction

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  • (PMID = 17549343.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Epstein-Barr Virus Nuclear Antigens; 0 / RNA Probes; 0 / RNA, Messenger; 0 / RNA, Viral
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29. Zugor V, Krot D, Kühn R, Schrott KM, Schott GE: [Wilms' tumors in adults]. Urologe A; 2007 Apr;46(4):402, 404-5
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  • [Title] [Wilms' tumors in adults].
  • [Transliterated title] Wilms-Tumoren im Erwachsenenalter.
  • Wilms' tumors develop from persistent, primitive metanephrogenic stem cells.
  • Their biology and etiology in adults is still unknown even though remnants of primitive metanephrogenic tissue, which tends to malignancy, is suspected, and there are very few scientific studies on the biology of Wilms' tumors in adults.
  • Such a tumor occurs at a rate of 0.2/million adults in Europe and the USA.
  • In this article, we describe the course of the disease in two adults with histologically confirmed Wilms' tumors.
  • Both patients underwent a radical nephrectomy followed by chemotherapy as indicated by the SIOP nephroblastoma study.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Kidney Neoplasms / diagnosis. Kidney Neoplasms / drug therapy. Wilms Tumor / diagnosis. Wilms Tumor / drug therapy
  • [MeSH-minor] Adolescent. Adult. Dactinomycin / administration & dosage. Female. Humans. Treatment Outcome. Vincristine / administration & dosage

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  • (PMID = 17237959.001).
  • [ISSN] 0340-2592
  • [Journal-full-title] Der Urologe. Ausg. A
  • [ISO-abbreviation] Urologe A
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 1CC1JFE158 / Dactinomycin; 5J49Q6B70F / Vincristine; SIOP protocol
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30. Kositsyna IV, Tereshchenko SN, Golubev AV, Draganenko SI, Zhirov IV: [Myocardial metastasis of Wilms' tumor as a cause of focal electrocardiographic changes]. Ter Arkh; 2010;82(4):62-4
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  • [Title] [Myocardial metastasis of Wilms' tumor as a cause of focal electrocardiographic changes].
  • Nephroblastoma (Wilms' tumor) is an embryonic tumor, an adenomyosarcoma that is casuistically rarely encountered in adults.
  • The paper presents a clinical case of Wilms' tumor in an adult female patient with a solitary metastasis in the heart.
  • [MeSH-major] Electrocardiography. Heart Neoplasms / secondary. Kidney Neoplasms / pathology. Myocardium / pathology. Wilms Tumor / secondary

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  • (PMID = 20481219.001).
  • [ISSN] 0040-3660
  • [Journal-full-title] Terapevticheskiĭ arkhiv
  • [ISO-abbreviation] Ter. Arkh.
  • [Language] rus
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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31. Lehmberg K, Steinhausen B, Janka G: From neonates to adolescents--the diagnostic significance of pitted erythrocytes in hyposplenic and asplenic children. Klin Padiatr; 2007 Nov-Dec;219(6):339-42
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  • This included splenectomized individuals, patients at risk for hyposplenia (homozygous sickle cell anemia (HbSS), leukemia, nephroblastoma and Hodgkin's disease after irradiation, patients after stem cell transplantation (SCT)), term and preterm neonates, and 90 controls (0-20 years of age, no neonates).
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Homozygote. Humans. Infant. Infant, Newborn. Microscopy, Interference. Reproducibility of Results

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  • (PMID = 18050044.001).
  • [ISSN] 0300-8630
  • [Journal-full-title] Klinische Pädiatrie
  • [ISO-abbreviation] Klin Padiatr
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] Germany
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32. Schluth C, Mattei MG, Mignon-Ravix C, Salman S, Alembik Y, Willig J, Ginglinger E, Jeandidier E: Intrachromosomal triplication for the distal part of chromosome 15q. Am J Med Genet A; 2005 Jul 15;136(2):179-84

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  • He underwent treatment for unilateral nephroblastoma at 6 years old.
  • [MeSH-minor] Adult. Child. Chromosome Banding. Face / abnormalities. Follow-Up Studies. Humans. In Situ Hybridization, Fluorescence. Infant, Newborn. Intellectual Disability / pathology. Karyotyping. Male. Mosaicism. Phenotype. Scoliosis / pathology. Wilms Tumor / pathology

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  • [Copyright] Copyright 2005 Wiley-Liss, Inc.
  • (PMID = 15940678.001).
  • [ISSN] 1552-4825
  • [Journal-full-title] American journal of medical genetics. Part A
  • [ISO-abbreviation] Am. J. Med. Genet. A
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 27
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33. Radhika S, Bakshi A, Rajwanshi A, Nijhawan R, Das A, Kakkar N, Joshi K, Marwaha RK, Rao KL: Cytopathology of uncommon malignant renal neoplasms in the pediatric age group. Diagn Cytopathol; 2005 May;32(5):281-6
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  • [Title] Cytopathology of uncommon malignant renal neoplasms in the pediatric age group.
  • Malignant renal neoplasms are common solid tumors in pediatric oncology practice.
  • These include the common Wilms' tumor/nephroblastoma and the uncommon neoplasms such as clear-cell sarcoma of the kidney (CCSK), rhabdoid tumor, renal-cell carcinoma, and others.
  • The aim of this study was to describe in detail the cytopathological features of the histopathologically proven uncommon pediatric renal tumors.
  • Aspirates from Wilms' tumor, which are mesenchyme predominant, show clusters of spindle cells associated with the matrix material.
  • Renal-cell carcinoma of childhood shows similar cytological features as its adult counterpart.
  • Rhabdoid tumor of the kidney is characterized by a monomorphic population of cells with abundant cytoplasm, eccentric nuclei with prominent nucleoli.
  • Intrarenal yolk sac tumor is a rare neoplasm and shows severely pleomorphic cells on aspiration.
  • Further, non-Wilms' renal malignant neoplasms must be distinguished from the common Wilms' tumor so that appropriate chemotherapy protocols may be instituted in cases where the tumor is in an advanced stage of malignancy.
  • [MeSH-major] Biopsy, Fine-Needle / methods. Carcinoma, Renal Cell / pathology. Endodermal Sinus Tumor / pathology. Kidney Neoplasms / pathology. Rhabdoid Tumor / pathology. Sarcoma, Clear Cell / pathology
  • [MeSH-minor] Adolescent. Cell Nucleus / pathology. Child. Child, Preschool. Diagnosis, Differential. Humans. Infant. Staining and Labeling. Wilms Tumor / pathology

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  • [Copyright] Copyright 2005 Wiley-Liss, Inc.
  • (PMID = 15830360.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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34. Goussard P, Gie RP, Kling S, Nel ED, Louw M, Schubert PT, Rhode D, Vanker A, Andronikou S: The diagnostic value and safety of transbronchial needle aspiration biopsy in children with mediastinal lymphadenopathy. Pediatr Pulmonol; 2010 Dec;45(12):1173-9
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  • Transbronchial needle aspiration (TBNA) has been described as a safe and effective diagnostic procedure in adult patients with lung cancer.
  • A definitive diagnosis was made by TBNA in 54% (n = 15) of patients; MTB lymphadenopathy (n = 13), metastatic nephroblastoma (n = 1), and fibrosing mediastinitis (n = 1).
  • [MeSH-minor] Adolescent. Bronchoscopy. Child. Child, Preschool. Female. Fibrosis / diagnosis. Humans. Infant. Male. Mediastinal Neoplasms / diagnosis. Mediastinal Neoplasms / secondary. Mediastinitis / diagnosis. Mediastinum / pathology. Mycobacterium tuberculosis / isolation & purification. Prospective Studies. Radiography, Thoracic. Tuberculosis / diagnosis. Wilms Tumor / diagnosis. Wilms Tumor / secondary

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  • [Copyright] Copyright © 2010 Wiley-Liss, Inc.
  • (PMID = 20717911.001).
  • [ISSN] 1099-0496
  • [Journal-full-title] Pediatric pulmonology
  • [ISO-abbreviation] Pediatr. Pulmonol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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35. Taskinen S, Lohi J, Kivisaari R, Fagerholm R, Rintala R, Taskinen M: Segmental cystic kidney tumours in children. Scand J Urol Nephrol; 2009;43(6):476-81
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  • [Title] Segmental cystic kidney tumours in children.
  • OBJECTIVE: Segmental cystic tumours in the kidney are extremely rare in children.
  • MATERIAL AND METHODS: The operative database from 1993 to 2008 of the Hospital for Children and Adolescents, University of Helsinki, was evaluated for segmental cystic renal tumours without any solid component.
  • All patients underwent kidney-preserving surgery with resection of the cystic tumour.
  • Two patients had neoplasias: one cystic nephroma and one cystic partially differentiated nephroblastoma.
  • Two patients had a non-neoplastic tumour; localized cystic disease of the kidney and segmental adult type autosomal dominant polycystic kidney disease.
  • CONCLUSIONS: Preoperative and perioperative diagnosis is difficult in cases of segmental cystic kidney tumours in a child.
  • [MeSH-major] Kidney / pathology. Kidney Diseases, Cystic / diagnosis. Kidney Diseases, Cystic / pathology
  • [MeSH-minor] Child, Preschool. Diagnosis, Differential. Female. Humans. Incidence. Infant. Infant, Newborn. Kidney Neoplasms / diagnosis. Kidney Neoplasms / pathology. Kidney Neoplasms / surgery. Magnetic Resonance Imaging. Male. Polycystic Kidney, Autosomal Dominant / diagnosis. Polycystic Kidney, Autosomal Dominant / pathology. Polycystic Kidney, Autosomal Dominant / surgery. Wilms Tumor / diagnosis. Wilms Tumor / pathology. Wilms Tumor / surgery

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  • (PMID = 19968582.001).
  • [ISSN] 1651-2065
  • [Journal-full-title] Scandinavian journal of urology and nephrology
  • [ISO-abbreviation] Scand. J. Urol. Nephrol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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36. Singam P, Ho C, Hong GE, Mohd A, Tamil AM, Cheok LB, Zainuddin Z: Clinical characteristics of renal cancer in Malaysia : a ten year review. Asian Pac J Cancer Prev; 2010;11(2):503-6
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  • [Title] Clinical characteristics of renal cancer in Malaysia : a ten year review.
  • Renal cancer is rare and its incidence is 1.9 per 100,000 in the Malaysian population, which consists of three major ethnic groups (Malay, Chinese and Indians).
  • The study included all renal cancer patients from a single medical institution over ten years, with a total of 75 cases.
  • Tumour histology were clear cell (72%), urothelial cell (13.3%), sarcomatoid cell and nephroblastoma each contributed 2.7%.
  • In conclusion we observed significant influences of age and race in the clinical presentation of renal cancer in our institution based population.
  • [MeSH-major] Carcinoma, Papillary / therapy. Carcinoma, Renal Cell / therapy. Carcinoma, Squamous Cell / therapy. Kidney Neoplasms / therapy. Wilms Tumor / therapy
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Antineoplastic Agents / therapeutic use. Combined Modality Therapy. Female. Humans. Incidence. Malaysia. Male. Middle Aged. Neoplasm Staging. Prognosis. Radiotherapy Dosage. Risk Factors. Survival Rate. Time Factors. Young Adult

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  • (PMID = 20843141.001).
  • [ISSN] 2476-762X
  • [Journal-full-title] Asian Pacific journal of cancer prevention : APJCP
  • [ISO-abbreviation] Asian Pac. J. Cancer Prev.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Thailand
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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37. Stefanowicz J, Owczuk R, Sierota D, Kaczorowska-Hać B, Balcerska A: Does antineoplasm treatment decrease the glomerular filtration rate in children? Kidney Blood Press Res; 2009;32(3):194-9
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  • BACKGROUND: The aim of this cross-sectional study was to test the hypothesis that children diagnosed with nephroblastoma experience increased disturbance in renal filtration even after prompt treatment compared to patients treated for other neoplastic childhood diseases.
  • PROCEDURES: Our study included 127 children and young adults, who were successfully treated for nephroblastoma (n = 34), oncohaematological childhood diseases (n = 58), and other solid tumours (n = 35).
  • RESULTS: Our studies show that patients who were successfully treated for nephroblastoma and other solid tumours have lower GFR (GFR(Sch) 118 +/- 20, p = 0.00006, and 117 +/- 22, p = 0.00003; GFR(Filler) 99 +/- 17, p = 0.0001, and 104 +/- 21 ml/min/1.73 m(2), p = 0.0002) than children treated for oncohaematological diseases (GFR(Sch) 137 +/- 19, GFR(Filler) 121 +/- 18 ml/min/1.73 m(2)).
  • CONCLUSIONS: Patients diagnosed with nephroblastoma and other solid tumours have lower eGFR than children with oncohaematological childhood diseases and are at higher risk for developing CKD.
  • [MeSH-major] Antineoplastic Agents / adverse effects. Glomerular Filtration Rate / drug effects. Wilms Tumor / drug therapy
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Cross-Sectional Studies. Female. Hematologic Neoplasms. Humans. Kidney Function Tests. Male. Neoplasms. Remission Induction. Treatment Outcome. Young Adult

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  • [Copyright] Copyright (c) 2009 S. Karger AG, Basel.
  • (PMID = 19521109.001).
  • [ISSN] 1423-0143
  • [Journal-full-title] Kidney & blood pressure research
  • [ISO-abbreviation] Kidney Blood Press. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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38. Niu Z, Ito M, Awakura Y, Takahashi T, Nakamura E, Ito N, Ogawa O: The expression of NOV and WT1 in renal cell carcinoma: a quantitative reverse transcriptase-polymerase chain reaction analysis. J Urol; 2005 Oct;174(4 Pt 1):1460-2
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  • [Title] The expression of NOV and WT1 in renal cell carcinoma: a quantitative reverse transcriptase-polymerase chain reaction analysis.
  • We analyzed the mRNA level of human NOV together with the mRNA level of WT1 in sporadic renal cell carcinoma (RCC).
  • RESULTS: NOV mRNA levels decreased significantly in RCC compared with normal kidney tissue (p <0.001).
  • CONCLUSIONS: To our knowledge this is the first study to investigate the expression level of the NOV gene in a panel of human RCC tissues together with paired normal renal tissue.
  • [MeSH-major] Carcinoma, Renal Cell / metabolism. Immediate-Early Proteins / metabolism. Intercellular Signaling Peptides and Proteins / metabolism. WT1 Proteins / metabolism
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Connective Tissue Growth Factor. Disease Progression. Down-Regulation. Female. Gene Expression. Humans. Kidney Neoplasms. Male. Middle Aged. Nephroblastoma Overexpressed Protein. Reverse Transcriptase Polymerase Chain Reaction

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  • (PMID = 16145471.001).
  • [ISSN] 0022-5347
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CTGF protein, human; 0 / Immediate-Early Proteins; 0 / Intercellular Signaling Peptides and Proteins; 0 / NOV protein, human; 0 / Nephroblastoma Overexpressed Protein; 0 / WT1 Proteins; 139568-91-5 / Connective Tissue Growth Factor
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39. Nggada HA, Eni UE, Nwankwo EA: Histopathological findings in nephrectomy specimens--A review of 42 cases. Niger Postgrad Med J; 2006 Sep;13(3):244-6
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  • Nephroblastoma, the second commonest, accounted for 23.8% of all cases and is the major malignant indication for nephrectomies.
  • Renal cell carcinoma and hydronephrosis accounted for 7(16.7%) cases each; polycystic kidney, transitional cell carcinoma and non-Hodgkin's lymphoma.
  • [MeSH-major] Carcinoma, Renal Cell / pathology. Kidney Neoplasms / pathology. Nephrectomy. Pyelonephritis / pathology. Wilms Tumor / pathology
  • [MeSH-minor] Adolescent. Adult. Child. Female. Humans. Hydronephrosis / pathology. Male. Middle Aged. Polycystic Kidney Diseases / pathology. Retrospective Studies

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  • (PMID = 17278316.001).
  • [ISSN] 1117-1936
  • [Journal-full-title] The Nigerian postgraduate medical journal
  • [ISO-abbreviation] Niger Postgrad Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nigeria
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40. Reinhard H, Furtwängler R, Siemer S, Wullich B, Graf N: [Wilms' tumor in adults]. Urologe A; 2007 Jul;46(7):748-53
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  • [Title] [Wilms' tumor in adults].
  • [Transliterated title] Wilms-Tumor bei Erwachsenen.
  • BACKGROUND: Wilms' tumor (nephroblastoma) is the most frequent renal tumor in childhood.
  • In contrast nephroblastoma in adults is rare, and the disease used to have a poor prognosis.
  • PATIENTS AND METHODS: Of 1,300 registered patients, a total of 41 patients older than 16 years were enrolled in the pediatric nephroblastoma trial from 1994 to 2005.
  • CONCLUSION: Adults with nephroblastoma have a very good prognosis if treated according to a pediatric protocol.
  • [MeSH-major] Kidney Neoplasms / drug therapy. Kidney Neoplasms / epidemiology. Risk Assessment / methods. Vincristine / therapeutic use. Wilms Tumor / drug therapy. Wilms Tumor / epidemiology
  • [MeSH-minor] Adolescent. Adult. Antineoplastic Agents, Phytogenic / therapeutic use. Female. Germany / epidemiology. Humans. Male. Middle Aged. Prevalence. Risk Factors. Treatment Outcome

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  • (PMID = 17505815.001).
  • [ISSN] 0340-2592
  • [Journal-full-title] Der Urologe. Ausg. A
  • [ISO-abbreviation] Urologe A
  • [Language] ger
  • [Publication-type] Clinical Trial; English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; 5J49Q6B70F / Vincristine
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41. Stewénius Y, Jin Y, Ora I, Panagopoulos I, Möller E, Mertens F, Sandstedt B, Alumets J, Akerman M, Merks JH, de Kraker J, Gisselsson D: High-resolution molecular cytogenetic analysis of Wilms tumors highlights diagnostic difficulties among small round cell kidney tumors. Genes Chromosomes Cancer; 2008 Oct;47(10):845-52
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  • [Title] High-resolution molecular cytogenetic analysis of Wilms tumors highlights diagnostic difficulties among small round cell kidney tumors.
  • In Wilms tumor (WT, nephroblastoma) no fusions genes or recurrent balanced translocations have been described thus far.
  • To screen for cryptic balanced translocations, we have analyzed 17 renal neoplasms, histopathologically classified as WT, by a combination of G-banding, multicolor FISH, and subtelomeric FISH.
  • As EWSR1 rearrangements are known to be a characteristic of Ewing tumors (ET), our findings illustrate the diagnostic problems regarding small cell kidney tumors and strongly argue for the need of adjuvant diagnostic techniques in this group of neoplasms.
  • [MeSH-major] Chromosome Aberrations. Kidney Neoplasms / genetics. Translocation, Genetic. Wilms Tumor / genetics
  • [MeSH-minor] Adult. Child. Child, Preschool. Chromosome Banding. Chromosomes, Human / genetics. Diagnosis, Differential. Humans. In Situ Hybridization, Fluorescence. Infant. Karyotyping. Oncogene Proteins, Fusion / genetics. Proto-Oncogene Protein c-fli-1. RNA, Messenger / genetics. RNA, Messenger / metabolism. RNA, Neoplasm / genetics. RNA-Binding Protein EWS. Reverse Transcriptase Polymerase Chain Reaction. Telomere / genetics. Transcription Factors / genetics. Tumor Cells, Cultured. Ubiquitin-Protein Ligases / genetics

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  • (PMID = 18615675.001).
  • [ISSN] 1098-2264
  • [Journal-full-title] Genes, chromosomes & cancer
  • [ISO-abbreviation] Genes Chromosomes Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / EWS-ERG fusion protein, human; 0 / EWS-FLI fusion protein; 0 / Oncogene Proteins, Fusion; 0 / Proto-Oncogene Protein c-fli-1; 0 / RNA, Messenger; 0 / RNA, Neoplasm; 0 / RNA-Binding Protein EWS; 0 / Transcription Factors; EC 6.3.2.19 / HACE1 protein, human; EC 6.3.2.19 / Ubiquitin-Protein Ligases
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42. Hodorova I, Rybarova S, Vecanova J, Plank L, Kluchova D: Immunohistochemical detection of MDR proteins in Wilms' tumour. Bratisl Lek Listy; 2008;109(12):564-7
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  • [Title] Immunohistochemical detection of MDR proteins in Wilms' tumour.
  • OBJECTIVES: The aim of our work was to determine the expression of three MDR proteins (MDR1/Pgp, MRP1 and LRP/MVP) in 15 tissue samples of nephroblastoma (Wilms' tumour).
  • BACKGROUND: The majority of Wilms' tumours respond well to chemotherapy and are successfully cured, but a small subset displays resistance to therapy.
  • CONCLUSION: Our immunohistochemical analysis did not demonstrate any expression of MDR1 in all cases of nephroblastoma (14 cases were after pre-operative chemotherapy, 1 case wasn't).
  • [MeSH-major] Kidney Neoplasms / chemistry. Multidrug Resistance-Associated Proteins / analysis. Vault Ribonucleoprotein Particles / analysis. Wilms Tumor / chemistry
  • [MeSH-minor] Adult. Child, Preschool. Drug Resistance, Neoplasm. Humans. Immunohistochemistry

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  • (PMID = 19348379.001).
  • [ISSN] 0006-9248
  • [Journal-full-title] Bratislavské lekárske listy
  • [ISO-abbreviation] Bratisl Lek Listy
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Slovakia
  • [Chemical-registry-number] 0 / Multidrug Resistance-Associated Proteins; 0 / Vault Ribonucleoprotein Particles; 0 / major vault protein
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43. Wolk M, Martin JE, Nowicki M: Foetal haemoglobin-blood cells (F-cells) as a feature of embryonic tumours (blastomas). Br J Cancer; 2007 Aug 6;97(3):412-9

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  • In the three, main blastoma types, nephroblastoma (Wilms' tumour), neuroblastoma and retinoblastoma, where all the patients, except two, were children, around 80% of the tumour samples had Fc within proliferating blood vessels and spaces between tumour cells.
  • [MeSH-major] Biomarkers, Tumor / blood. Fetal Hemoglobin / analysis. Neoplasms, Germ Cell and Embryonal / blood
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. DNA Methylation. Female. Humans. Immunohistochemistry. Male. Middle Aged

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  • [Cites] J Med Genet. 2000 Aug;37(8):615-20 [10991691.001]
  • [Cites] J Clin Pathol. 2006 Jun;59(6):598-602 [16469830.001]
  • [Cites] Pediatr Hematol Oncol. 2001 Mar;18(2):101-10 [11255727.001]
  • [Cites] Cancer Lett. 2001 May 26;166(2):165-71 [11311489.001]
  • [Cites] Med Pediatr Oncol. 2001 Feb;36(2):290-4 [11452937.001]
  • [Cites] Oncogene. 2002 Jan 24;21(5):789-97 [11850807.001]
  • [Cites] Cell Growth Differ. 2002 Jul;13(7):297-305 [12133898.001]
  • [Cites] Oncogene. 2002 Sep 26;21(43):6694-702 [12242669.001]
  • [Cites] Ann Hematol. 2002 Sep;81(9):548-50 [12373361.001]
  • [Cites] Science. 2003 Apr 18;300(5618):489-92 [12702876.001]
  • [Cites] Cancer Chemother Biol Response Modif. 2002;20:605-25 [12703226.001]
  • [Cites] Clin Chem Lab Med. 2003 May;41(5):646-51 [12812262.001]
  • [Cites] Hematology Am Soc Hematol Educ Program. 2003;:14-39 [14633775.001]
  • [Cites] Blood. 2004 Apr 1;103(7):2753-60 [14656887.001]
  • [Cites] J Clin Pathol. 2004 Jul;57(7):740-5 [15220368.001]
  • [Cites] Int J Biol Markers. 2004 Apr-Jun;19(2):168-9 [15255552.001]
  • [Cites] Br J Haematol. 2004 Sep;126(5):629-36 [15327513.001]
  • [Cites] Nature. 1983 Jan 6;301(5895):89-92 [6185846.001]
  • [Cites] Cancer Res. 1987 Aug 1;47(15):4199-201 [2440559.001]
  • [Cites] Blut. 1990 Jul;61(1):17-20 [1696840.001]
  • [Cites] Tumour Biol. 1991;12(1):45-51 [1705048.001]
  • [Cites] Blood. 1996 Mar 15;87(6):2171-9 [8630376.001]
  • [Cites] Ann Hematol. 1998 Mar-Apr;76(3-4):135-8 [9619730.001]
  • [Cites] Semin Hematol. 2004 Oct;41(4 Suppl 6):3-10 [15534851.001]
  • [Cites] Clin Exp Dermatol. 2004 Nov;29(6):605-7 [15550132.001]
  • [Cites] Cancer Genet Cytogenet. 2005 Jan 1;156(1):31-6 [15588853.001]
  • [Cites] J Urol. 2005 Jan;173(1):243-6 [15592089.001]
  • [Cites] Biochemistry (Mosc). 2005 May;70(5):568-75 [15948710.001]
  • [Cites] Cancer Lett. 2005 Oct 18;228(1-2):37-41 [15923079.001]
  • [Cites] Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13580-5 [16174748.001]
  • [Cites] Breast Cancer Res Treat. 2006 Feb;95(3):219-28 [16244790.001]
  • [Cites] Cancer Res. 2000 Nov 15;60(22):6288-92 [11103785.001]
  • (PMID = 17595660.001).
  • [ISSN] 0007-0920
  • [Journal-full-title] British journal of cancer
  • [ISO-abbreviation] Br. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 9034-63-3 / Fetal Hemoglobin
  • [Other-IDs] NLM/ PMC2360326
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44. Kremens B: [Systemic therapy in children and adolescents]. Urologe A; 2007 Oct;46(10):1404-6

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  • National and supranational treatment studies are the standard of care for pediatric cancer in Germany; they yield 5-year survival rates of almost 90% for nephroblastoma and germ cell tumors and 60% for neuroblastoma (all stages) and rhabdomyosarcoma.
  • The principles of antineoplastic therapy are the same as in adult cancer medicine; the drugs used depend upon the disease.
  • In a multimodal treatment strategy, the role of chemotherapy as well as that of surgery and radiotherapy can differ, as is described for nephroblastoma, infant neuroblastoma, and stage 4 neuroblastoma.
  • [MeSH-minor] Adolescent. Adrenal Gland Neoplasms / drug therapy. Adrenal Gland Neoplasms / mortality. Adrenal Gland Neoplasms / pathology. Adrenal Gland Neoplasms / surgery. Adrenal Medulla. Chemotherapy, Adjuvant. Child. Child, Preschool. Combined Modality Therapy. Humans. Infant. Kidney Neoplasms / drug therapy. Kidney Neoplasms / mortality. Kidney Neoplasms / pathology. Kidney Neoplasms / surgery. Neoplasm Staging. Neoplasms, Germ Cell and Embryonal / drug therapy. Neoplasms, Germ Cell and Embryonal / mortality. Neoplasms, Germ Cell and Embryonal / pathology. Neoplasms, Germ Cell and Embryonal / surgery. Neuroblastoma / drug therapy. Neuroblastoma / mortality. Neuroblastoma / pathology. Neuroblastoma / surgery. Prognosis. Radiotherapy, Adjuvant. Rhabdomyosarcoma / drug therapy. Rhabdomyosarcoma / mortality. Rhabdomyosarcoma / pathology. Rhabdomyosarcoma / surgery. Survival Rate. Wilms Tumor / drug therapy. Wilms Tumor / mortality. Wilms Tumor / pathology. Wilms Tumor / surgery

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  • (PMID = 17823786.001).
  • [ISSN] 0340-2592
  • [Journal-full-title] Der Urologe. Ausg. A
  • [ISO-abbreviation] Urologe A
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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45. Terao H, Matsumoto T, Umemoto S, Onuki T, Kobayashi K, Ohgo Y, Nogcchi S, Kishi H, Tsuura Y, Nagashima Y: [Metanephric adenoma: report of two cases]. Hinyokika Kiyo; 2008 Sep;54(9):599-602
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  • One case occurred in a 54-year-old male preoperatively diagnosed with renal cell carcinoma who underwent left partial nephrectomy for a tumor 2 cm in size.
  • Histology revealed a tumor with papillotubular structures consisting of small, uniform tumor cells.
  • In immunohistochemical staining, tumor cells were positive for CD57 and WT-1.
  • The other case occurred in a 40-year-old male who underwent left nephroureterectomy for carcinoma of the renal pelvis.
  • Carcinoma of the left renal pelvis was diagnosed as pT3N0M0.
  • Incidental micronodules 2 mm in size and consisting of immature tubular structures were noted in the renal cortex.
  • In immunohistochemical staining, tumor cells were positive for CD57 and WT-1, and the patient was diagnosed with metanephric adenoma.
  • The aforementioned tumors frequently occur in middle-aged women and are often well-defined tumors that project from the renal surface outwards.
  • On angiography, they have a hypovascular pattern and resemble papillary renal carcinoma.
  • Preoperative differentiation of renal cell carcinoma and nephroblastoma is difficult.
  • [MeSH-major] Adenoma / diagnosis. Kidney Neoplasms / diagnosis
  • [MeSH-minor] Adult. Antigens, CD57 / analysis. Biomarkers, Tumor / analysis. Diagnosis, Differential. Humans. Kidney Pelvis. Male. Middle Aged. Neoplasm Staging. Nephrectomy. Tomography, X-Ray Computed. Ureter / surgery. WT1 Proteins / analysis

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  • (PMID = 18975573.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antigens, CD57; 0 / Biomarkers, Tumor; 0 / WT1 Proteins
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46. Rehman J, Chughtai B, Guru K, Khan SA, Adler HL, Miller F: Wilm's tumor during pregnancy: report of laparoscopic removal and review of literature. Can J Urol; 2008 Aug;15(4):4180-3
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  • [Title] Wilm's tumor during pregnancy: report of laparoscopic removal and review of literature.
  • Wilm's tumor, or nephroblastoma, is a common renal tumor among children.
  • Few cases of Wilm's tumor have been reported in women during pregnancy.
  • The authors present a rare case of a pregnant female, who underwent laparoscopic excision of a large Wilm's tumor.
  • [MeSH-major] Kidney Neoplasms / surgery. Laparoscopy / methods. Nephrectomy / methods. Pregnancy Complications, Neoplastic. Wilms Tumor / surgery
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Pregnancy. Pregnancy Outcome. Tomography, X-Ray Computed


47. Wagner-Bohn A, Paulussen M, Vieira Pinheiro JP, Gerss J, Stoffregen C, Boos J: Phase II study of gemcitabine in children with solid tumors of mesenchymal and embryonic origin. Anticancer Drugs; 2006 Aug;17(7):859-64
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  • To determine the efficacy and tolerability of gemcitabine in children, the drug was administered by intravenous short-term infusion over 30 min at a dose of 1200 mg/m2 weekly for 3 weeks as one cycle in children with relapsed solid tumor of embryonic or mesenchymal origin.
  • The patients suffered from rhabdomyosarcoma (n=8), Ewing's sarcoma (n=4), osteosarcoma (n=2), neuroblastoma (n=3), hepatoblastoma (n=2) and nephroblastoma (n=1).
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Female. Humans. Male. Prospective Studies. Sample Size

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  • (PMID = 16926636.001).
  • [ISSN] 0959-4973
  • [Journal-full-title] Anti-cancer drugs
  • [ISO-abbreviation] Anticancer Drugs
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0W860991D6 / Deoxycytidine; B76N6SBZ8R / gemcitabine
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48. Oda E, Nakamura Y, Yamamoto M, Kojiro M: Immunohistochemical distribution of tubulin beta II in human normal and neoplastic tissues. Kurume Med J; 2005;52(4):117-25
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  • Tubulin beta II was detected in various normal tissues, particularly in fetal and neonatal tissues, such as the nervous system, pulmonary alveoli, bronchioles and bronchi, colon, pancreatic ducts and acini, renal convoluted tubuli, skin epidermis, body cavity mesothelial cells, smooth muscle and thymus.
  • In the adult, broad expression was also observed; however, the immunoreactivity was weaker and the extent of its distribution decreased with age.
  • In neoplastic tissues, tubulin beta II immunoreactivity was detected in various nervous system neoplasms and other neoplasms such as pancreatic solid cystic carcinoma, pleomorphic adenoma, Warthin's tumor, nephroblastoma, basal cell carcinoma and malignant mesothelioma.
  • We conclude that our monoclonal antibody, KNY379, may be useful as a marker of nervous system neoplasm, pancreatic solid cystic carcinoma, pleomorphic adenoma, Warthin's tumor, nephroblastoma, basal cell carcinoma and malignant mesothelioma.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / analysis. Blotting, Western. Child, Preschool. Humans. Immunohistochemistry. Infant. Mesothelioma / chemistry. Middle Aged. Protein Isoforms

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  • (PMID = 16639982.001).
  • [ISSN] 0023-5679
  • [Journal-full-title] The Kurume medical journal
  • [ISO-abbreviation] Kurume Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Protein Isoforms; 0 / Tubulin
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49. Bahubeshi A, Bal N, Rio Frio T, Hamel N, Pouchet C, Yilmaz A, Bouron-Dal Soglio D, Williams GM, Tischkowitz M, Priest JR, Foulkes WD: Germline DICER1 mutations and familial cystic nephroma. J Med Genet; 2010 Dec;47(12):863-6
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  • BACKGROUND: Multilocular cystic nephroma (CN) is a benign kidney tumour and is part of a family of kidney neoplasms including cystic partially differentiated nephroblastoma and Wilms tumour (WT).
  • [MeSH-major] DEAD-box RNA Helicases / genetics. Germ-Line Mutation / genetics. Kidney Diseases, Cystic / complications. Kidney Diseases, Cystic / genetics. Kidney Neoplasms / complications. Kidney Neoplasms / genetics. Ribonuclease III / genetics
  • [MeSH-minor] Adolescent. Adult. Base Sequence. Child. Child, Preschool. DNA Mutational Analysis. Family. Female. Humans. Infant. Male. Middle Aged. Molecular Sequence Data. Pedigree. Young Adult

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  • (PMID = 21036787.001).
  • [ISSN] 1468-6244
  • [Journal-full-title] Journal of medical genetics
  • [ISO-abbreviation] J. Med. Genet.
  • [Language] eng
  • [Grant] Canada / Canadian Institutes of Health Research / / FRN53888
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] EC 3.1.26.3 / DICER1 protein, human; EC 3.1.26.3 / Ribonuclease III; EC 3.6.4.13 / DEAD-box RNA Helicases
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50. Mitry E, Ciccolallo L, Coleman MP, Gatta G, Pritchard-Jones K, EUROCARE Working Group: Incidence of and survival from Wilms' tumour in adults in Europe: data from the EUROCARE study. Eur J Cancer; 2006 Sep;42(14):2363-8
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  • [Title] Incidence of and survival from Wilms' tumour in adults in Europe: data from the EUROCARE study.
  • Wilms' tumour, or nephroblastoma, is an embryonal cancer of the kidney that occurs mainly in young children.
  • The aims of this study were to report the survival of adults diagnosed with nephroblastoma in Europe and to analyse time trends and geographic variations in survival.
  • All the adults (age range 15-99 years) diagnosed with a Wilms' tumour during 1983-1994 and registered by one of the 22 cancer registries in 16 countries contributing to the EUROCARE (European cancer registries study on cancer patients' survival and care) database were analysed.
  • Our results suggest a poorer outcome of nephroblastoma in adults compared with published results in children.
  • Prognosis may be improved by the use of specific treatment guidelines for nephroblastoma in adults.
  • [MeSH-major] Kidney Neoplasms / mortality. Wilms Tumor / mortality
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Europe / epidemiology. Female. Humans. Incidence. Male. Middle Aged. Registries. Survival Analysis

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  • (PMID = 16891111.001).
  • [ISSN] 0959-8049
  • [Journal-full-title] European journal of cancer (Oxford, England : 1990)
  • [ISO-abbreviation] Eur. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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51. Kiankhooy A, Sartorelli KH, Vane DW, Bhave AD: Angiographic embolization is safe and effective therapy for blunt abdominal solid organ injury in children. J Trauma; 2010 Mar;68(3):526-31

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  • BACKGROUND: : Angiographic embolization (AE) is used to control hemorrhage in adult blunt liver, spleen, and kidney (ASO) injuries.
  • RESULTS: : One hundred twenty-seven patients with 149 blunt ASO injuries were identified (72 spleen, 51 liver, and 26 renal).
  • Seven children underwent AE: two spleen (grades IV and V), two liver (grades III and IV), and three grade IV renal injuries.
  • A nephroblastoma was later found in one renal injury requiring nephrectomy.
  • [MeSH-major] Abdominal Injuries / therapy. Embolization, Therapeutic. Kidney / injuries. Liver / injuries. Spleen / injuries. Wounds, Nonpenetrating / therapy

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  • (PMID = 20220415.001).
  • [ISSN] 1529-8809
  • [Journal-full-title] The Journal of trauma
  • [ISO-abbreviation] J Trauma
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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52. Barr RD: Common cancers in adolescents. Cancer Treat Rev; 2007 Nov;33(7):597-602
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  • Adolescence, spanning 15-19 years of age, is a time of developmental transition from childhood to adult life.
  • The common malignant diseases of childhood - leukemias, lymphomas, tumors of the central nervous system and embryonal solid tumors (such as nephroblastoma and neuroblastoma) - are replaced in relative frequency by sarcomas of bone and soft tissue, and tumors of the male and female genital tracts.
  • Within individual tumor types, biological features may be distinctive in this age group.

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  • (PMID = 17222981.001).
  • [ISSN] 0305-7372
  • [Journal-full-title] Cancer treatment reviews
  • [ISO-abbreviation] Cancer Treat. Rev.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 52
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53. Brémond-Gignac D, Crolla JA, Copin H, Guichet A, Bonneau D, Taine L, Lacombe D, Baumann C, Benzacken B, Verloes A: Combination of WAGR and Potocki-Shaffer contiguous deletion syndromes in a patient with an 11p11.2-p14 deletion. Eur J Hum Genet; 2005 Apr;13(4):409-13
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  • Aniridia, Wilms tumor, genitourinary abnormalities, growth and mental retardation are the cardinal features of the WAGR 11p13 deletion syndrome.
  • A left nephroblastoma was detected at 15 months.
  • [MeSH-minor] Adolescent. Adult. Chromosome Mapping. Female. Humans. Karyotyping. Syndrome

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  • (PMID = 15702131.001).
  • [ISSN] 1018-4813
  • [Journal-full-title] European journal of human genetics : EJHG
  • [ISO-abbreviation] Eur. J. Hum. Genet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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54. Stefanowicz J, Grabiec-Wiśniewska A, Stachowicz-Stencel T, Adamkiewicz-Drozyńska E, Bień E, Kaczorowska-Hać B, Połczyńska K, Szołkiewicz A, Sierota D, Maciejka-Kapuścińska L, Płoszyńska A, Izycka-Swieszewska E, Szutowicz E, Czauderna P, Reiter M, Hennig M, Balcerska A: [Second neoplasms in children with solid tumours in the years 1992-2007. Experiences of Gdańsk medical academy]. Med Wieku Rozwoj; 2008 Oct-Dec;12(4 Pt 2):1141-7
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  • They were treated for nephroblastoma - 3 cases, soft tissue sarcoma - 2, Ewing's sarcoma - 1, medulloblastoma - 1, retinoblastoma - 1 and neuroblastoma - 1 case.
  • The second neoplasms were: acute non lymphoblastic leukaemia - 2, soft tissue sarcoma - 2, osteosarcoma - 2, chondrosarcoma - 1, renal cell carcinoma - 1 and glioblastoma multiforme - 1 case.
  • [MeSH-major] Leukemia, Myeloid, Acute / epidemiology. Neoplasms, Neuroepithelial / epidemiology. Neoplasms, Second Primary / epidemiology. Sarcoma / epidemiology. Wilms Tumor / epidemiology
  • [MeSH-minor] Adolescent. Adult. Child. Disease Progression. Female. Humans. Incidence. Male. Poland / epidemiology. Prognosis. Young Adult


55. Krawczuk-Rybak M, Leszczyńska E, Wysocka J, Zelazowska-Rutkowska B: [Anti-mullerian hormone in young women after chemotherapy and infradiaphragmatic radiotherapy for childhood cancer]. Pediatr Endocrinol Diabetes Metab; 2008;14(2):99-103
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  • PATIENTS AND METHODS: We analysed FSH, LH, estradiol and anti-mullerian hormone (AMH) levels on days 3-5 of a menstrual cycle in thirty three cancer survivors in mean age 19.1+/-4.7 years treated in age 12.0+/-5.6 years for Hodgkin Lymphoma (HL) (n=16), nephroblastoma (n=7), soft tissue sarcoma (n=4), germinal tumor (n=3), neuroblastoma (n=2), histiocytosis (n=1).
  • Particular analysis of all cases showed higher (>2 SD) FSH levels in 8 patients: 5 patients treated for HL with radiotherapy and higher total doses of procarbazine, nitrogen mustard and vinblastine; 2 patients treated for soft tissue sarcoma and one patient for Wilms tumor (all received radiotherapy).
  • Lowered AMH levels were found in 8 patients treated with chemo- and radiotherapy (4 - for HL, 2 - for Wilms tumor and 2 - for soft tissue sarcoma).
  • [MeSH-minor] Adolescent. Adult. Combined Modality Therapy / adverse effects. Female. Follicle Stimulating Hormone / metabolism. Hodgkin Disease / drug therapy. Hodgkin Disease / radiotherapy. Humans. Neoplasms / therapy. Ovary / drug effects. Ovary / radiation effects. Survivors


56. Headley SA, Saut JP, Maiorka PC: Nephroblastoma in an adult sheep. Vet Rec; 2006 Dec 16;159(25):850-2
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  • [Title] Nephroblastoma in an adult sheep.
  • [MeSH-major] Kidney Neoplasms / veterinary. Lung Neoplasms / veterinary. Sheep Diseases / diagnosis. Wilms Tumor / veterinary

  • MedlinePlus Health Information. consumer health - Kidney Cancer.
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  • (PMID = 17172481.001).
  • [ISSN] 0042-4900
  • [Journal-full-title] The Veterinary record
  • [ISO-abbreviation] Vet. Rec.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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57. Italiano A, Sirvent N, Michiels JF, Peyrade F, Otto J, Thyss A: Tumour response to paclitaxel in an adult with relapsed nephroblastoma. Lancet Oncol; 2005 Apr;6(4):252-3
Hazardous Substances Data Bank. TAXOL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tumour response to paclitaxel in an adult with relapsed nephroblastoma.
  • [MeSH-major] Antineoplastic Agents, Phytogenic / therapeutic use. Kidney Neoplasms / drug therapy. Paclitaxel / therapeutic use. Pregnancy Complications, Neoplastic / drug therapy. Wilms Tumor / drug therapy
  • [MeSH-minor] Adult. Female. Humans. Neoplasm Recurrence, Local / drug therapy. Pregnancy

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  • (PMID = 15811622.001).
  • [ISSN] 1470-2045
  • [Journal-full-title] The Lancet. Oncology
  • [ISO-abbreviation] Lancet Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; P88XT4IS4D / Paclitaxel
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