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4. Willems SM, Schrage YM, Baelde JJ, Briaire-de Bruijn I, Mohseny A, Sciot R, Bovée JV, Hogendoorn PC: Myxoid tumours of soft tissue: the so-called myxoid extracellular matrix is heterogeneous in composition. Histopathology; 2008 Mar;52(4):465-74
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Myxoid tumours of soft tissue: the so-called myxoid extracellular matrix is heterogeneous in composition.
  • AIM: Myxoid tumours of soft tissue are characterized by their so-called 'myxoid' extracellular matrix.
  • METHODS AND RESULTS: Using Alcian Blue staining with and without pretreatment with hyaluronidase and application of the critical electrolyte concentration method followed by densitometry, the glycosaminoglycan composition of three different myxoid tumours was studied.
  • The composition of glycosaminoglycans varied with tumour type and grade, despite their general characterization as myxoid tumours.
  • Intramuscular myxoma contained similar amounts of the various glycosaminoglycans as grade I myxofibrosarcoma; grade III myxofibrosarcoma contained less hyaluronic acid and more heparan sulphate, whereas extraskeletal myxoid chondrosarcoma contained predominantly chondroitin-4 and -6 sulphates.
  • CONCLUSIONS: The extracellular matrix of myxoid tumours of soft tissue has a heterogeneous composition consisting of, amongst others, glycosaminoglycans and albumin, which appear to play an active role in their morphogenesis.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Albumins / chemistry. Albumins / genetics. Alcian Blue / chemistry. Blotting, Western. Coloring Agents / chemistry. Female. Glycosaminoglycans / chemistry. Glycosaminoglycans / classification. Humans. In Situ Hybridization. Male. Middle Aged. Neoplasm Staging. RNA, Messenger / metabolism. Retrospective Studies. Tissue Array Analysis

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  • (PMID = 18315599.001).
  • [ISSN] 1365-2559
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Albumins; 0 / Coloring Agents; 0 / Glycosaminoglycans; 0 / RNA, Messenger; P4448TJR7J / Alcian Blue
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5. Zhang SK, Wang JG, Piao YS, Lu DH: A case of myxoid chondrosarcoma arising from caput costae. Ai Zheng; 2009 Aug;28(8):894-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of myxoid chondrosarcoma arising from caput costae.
  • [MeSH-major] Bone Neoplasms / diagnosis. Chondrosarcoma / diagnosis. Ribs
  • [MeSH-minor] Adult. Antibodies, Monoclonal, Murine-Derived / metabolism. Cell Nucleus / metabolism. Cytoplasm / metabolism. Humans. Magnetic Resonance Imaging. Male. S100 Proteins / metabolism. Tomography, X-Ray Computed. Vimentin / metabolism

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  • (PMID = 20380079.001).
  • [Journal-full-title] Ai zheng = Aizheng = Chinese journal of cancer
  • [ISO-abbreviation] Ai Zheng
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal, Murine-Derived; 0 / S100 Proteins; 0 / Vimentin; 0 / monoclonal antibody D2-40
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6. Noguchi H, Mitsuhashi T, Seki K, Tochigi N, Tsuji M, Shimoda T, Hasegawa T: Fluorescence in situ hybridization analysis of extraskeletal myxoid chondrosarcomas using EWSR1 and NR4A3 probes. Hum Pathol; 2010 Mar;41(3):336-42
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  • [Title] Fluorescence in situ hybridization analysis of extraskeletal myxoid chondrosarcomas using EWSR1 and NR4A3 probes.
  • Extraskeletal myxoid chondrosarcomas (EMCs) are characterized histologically by a cord-like or lace-like arrangement of small round cells or short spindle cells with eosinophilic cytoplasm distributed in a rich myxoid matrix.
  • [MeSH-major] Calmodulin-Binding Proteins / genetics. Chondrosarcoma / genetics. DNA-Binding Proteins / genetics. RNA-Binding Proteins / genetics. Receptors, Steroid / genetics. Receptors, Thyroid Hormone / genetics. Soft Tissue Neoplasms / genetics
  • [MeSH-minor] Adult. Aged. Female. Humans. In Situ Hybridization, Fluorescence. Male. Middle Aged. Neoplasm Proteins / genetics. Oncogene Fusion / genetics. Oncogene Proteins, Fusion / genetics. Reverse Transcriptase Polymerase Chain Reaction

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 19775727.001).
  • [ISSN] 1532-8392
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Calmodulin-Binding Proteins; 0 / DNA-Binding Proteins; 0 / EWSR1 protein, human; 0 / NR4A3 protein, human; 0 / Neoplasm Proteins; 0 / Oncogene Proteins, Fusion; 0 / RNA-Binding Proteins; 0 / Receptors, Steroid; 0 / Receptors, Thyroid Hormone
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7. Ehara S, Nishida J, Shiraishi H, Yoshioka H, Okada K, Sumiya H, Takano H: Skeletal recurrences and metastases of extraskeletal myxoid chondrosarcoma. Skeletal Radiol; 2007 Sep;36(9):823-7
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  • [Title] Skeletal recurrences and metastases of extraskeletal myxoid chondrosarcoma.
  • OBJECTIVE: The objective was to elucidate clinical and imaging features of skeletal involvement, recurrences, and metastases of extraskeletal myxoid chondrosarcoma.
  • CONCLUSION: Although skeletal metastases of chondrosarcoma of bone and soft tissue are rare, myxoid chondrosarcomas, currently classified tumors of uncertain differentiation, rarely metastasize and/or recur in the bones.
  • [MeSH-major] Bone Neoplasms / secondary. Chondrosarcoma / pathology. Chondrosarcoma / secondary. Lung Neoplasms / secondary. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Female. Humans. Male. Middle Aged. Multicenter Studies as Topic. Neoplasm Metastasis. Radiography. Recurrence. Retrospective Studies

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  • [Cites] Skeletal Radiol. 1993 Nov;22(8):595-9 [8291012.001]
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  • (PMID = 17437101.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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8. Mavrogenis AF, Patapis P, Papaparaskeva KT, Galanis EC, Papagelopoulos PJ: Extraskeletal myxoid chondrosarcoma of the perineum. Orthopedics; 2009 Mar;32(3):216
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extraskeletal myxoid chondrosarcoma of the perineum.
  • Extraskeletal myxoid chondrosarcoma is an aggressive tumor with significant metastatic potential.
  • A computed tomography-guided core needle biopsy was consistent with low-grade extraskeletal myxoid chondrosarcoma.
  • Histological analysis of the excised specimens was consistent with extraskeletal myxoid chondrosarcoma metastases.
  • Extraskeletal myxoid chondrosarcoma is an unusual soft tissue sarcoma with ultrastructural and molecular features distinct from that of skeletal myxoid chondrosarcoma.
  • The EWS-CHN gene fusion is highly specific to extraskeletal myxoid chondrosarcoma; the gene fusion is positive in >or=75% of cases.
  • Because of the prolonged survival of patients with extraskeletal myxoid chondrosarcoma, long-term follow-up is recommended for early detection of local recurrence or distant metastases.
  • [MeSH-major] Chondrosarcoma / secondary. Perineum / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Disease-Free Survival. Humans. Lung Neoplasms / secondary. Lung Neoplasms / surgery. Lymph Nodes / pathology. Lymphatic Metastasis. Magnetic Resonance Imaging. Male. Radiography, Thoracic. Thoracotomy. Treatment Outcome

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  • (PMID = 19309044.001).
  • [ISSN] 1938-2367
  • [Journal-full-title] Orthopedics
  • [ISO-abbreviation] Orthopedics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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9. Huang D, Sumegi J, Dal Cin P, Reith JD, Yasuda T, Nelson M, Muirhead D, Bridge JA: C11orf95-MKL2 is the resulting fusion oncogene of t(11;16)(q13;p13) in chondroid lipoma. Genes Chromosomes Cancer; 2010 Sep;49(9):810-8
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  • Chondroid lipoma, a rare benign adipose tissue tumor, may histologically resemble myxoid liposarcoma or extraskeletal myxoid chondrosarcoma, but is genetically distinct.

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  • [Copyright] (c) 2010 Wiley-Liss, Inc.
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  • (PMID = 20607705.001).
  • [ISSN] 1098-2264
  • [Journal-full-title] Genes, chromosomes & cancer
  • [ISO-abbreviation] Genes Chromosomes Cancer
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA036727-24S59009; United States / NCI NIH HHS / CA / 5 P30 CA036727-2452; United States / NCI NIH HHS / CA / P30 CA036727-24S59009; United States / NCI NIH HHS / CA / U-10-CA98543-091
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / MKL2 protein, human; 0 / RNA, Messenger; 0 / RNA, Neoplasm; 0 / Transcription Factors
  • [Other-IDs] NLM/ NIHMS203810; NLM/ PMC2904421
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29. Sorimachi T, Sasaki O, Nakazato S, Koike T, Shibuya H: Myxoid chondrosarcoma in the pineal region. J Neurosurg; 2008 Nov;109(5):904-7
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  • [Title] Myxoid chondrosarcoma in the pineal region.
  • The authors report a case of a myxoid chondrosarcoma of the pineal region in a 37-year-old woman who presented with an intratumoral hemorrhage.
  • Histological and immunohistochemical findings after the second surgery were consistent with a diagnosis of myxoid chondrosarcoma.
  • Radical excision of a tumor was considered to play an important role in the management of intracranial myxoid chondrosarcoma.
  • [MeSH-major] Bone Neoplasms / diagnosis. Chondrosarcoma / diagnosis. Pineal Gland
  • [MeSH-minor] Adult. Female. Hemorrhage / etiology. Humans. Magnetic Resonance Imaging

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  • (PMID = 18976082.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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30. Li BZ, Wang JW, Wei HQ: [Microcystic/reticular schwannoma occurring in cervical spine: report of a case with literature review]. Zhonghua Bing Li Xue Za Zhi; 2010 Jun;39(6):396-9
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  • The other component consisted of epithelial-like cells arranged in a reticular or lace-like pattern, amongst a myxoid matrix.
  • [MeSH-minor] Adult. Chondrosarcoma / metabolism. Chondrosarcoma / pathology. Chordoma / metabolism. Chordoma / pathology. Diagnosis, Differential. Glial Fibrillary Acidic Protein / metabolism. Humans. Male. Phosphopyruvate Hydratase / metabolism. S100 Proteins / metabolism. Sarcoma / metabolism. Sarcoma / pathology. Vimentin / metabolism

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  • (PMID = 21055157.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein; 0 / S100 Proteins; 0 / Vimentin; EC 4.2.1.11 / Phosphopyruvate Hydratase
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31. Wong NL, DI F: [Fine needle aspiration cytology of myxoid lesions of soft tissues: a study of 24 cases]. Zhonghua Bing Li Xue Za Zhi; 2007 Sep;36(9):619-23
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  • [Title] [Fine needle aspiration cytology of myxoid lesions of soft tissues: a study of 24 cases].
  • OBJECTIVE: To summarize the diagnostic features of fine needle aspiration cytology (FNAC) of myxoid lesions in soft tissue, and to define the cytological criteria for differentiating benign lesions from sarcomas and between various myxoid lesions.
  • METHODS: FNAC data of 24 soft tissue myxoid lesions (14 benign lesions, 10 malignant lesions) from 1993 to 2006 from Kiang Wu Hospital, Macau were reviewed in correlation with the clinical course or the results of biopsy.
  • RESULTS: Ganglion, myxoma, and myxoid nodular fasciitis were the most common benign myxoid lesions of the soft tissues, all of which had low cellularity and lack of marked cellular atypia in smears in common.
  • Myxoid nodular fasciitis was characterized by a pleomorphic pattern of proliferative cells and the presence of ganglion cell-like cells.
  • Myxoid liposarcoma, extraskeletal myxoid chondrosarcoma and myxofibrosarcoma were the most common myxoid sarcomas.
  • Myxoid liposarcoma exhibited branching chicken-wire like capillary vessels and/or lipoblasts; myxofibrosarcoma were prominent in both pleomorphic and atypia of the cells.
  • The data revealed that the diagnostic accuracy of FNAC was nearly 100% in differentiating benign and malignant myxoid lesions of the soft tissues.
  • The coordinate rate to the histopathology diagnosis of the common myxoid lesions of the soft tissues was above 75% (benign 71.4% and malignancy 80% respectively).
  • CONCLUSIONS: FNAC is an effective method in diagnosing myxoid lesions of soft tissue, in correlation with the clinical data and the accessory examinations.
  • FNAC can provide an objective basis for the treatment of myxoid lesions and prevention of unnecessary surgical operations.
  • [MeSH-major] Biopsy, Fine-Needle / methods. Fibrosarcoma / pathology. Ganglion Cysts / pathology. Liposarcoma, Myxoid / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Bone Neoplasms / pathology. Bone Neoplasms / surgery. Chondrosarcoma / pathology. Chondrosarcoma / surgery. Diagnosis, Differential. Fasciitis / pathology. Fasciitis / surgery. Female. Humans. Male. Middle Aged. Myxoma / pathology. Myxoma / surgery. Prognosis. Sarcoma / pathology. Sarcoma / surgery. Young Adult

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  • (PMID = 18070452.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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32. Wang WL, Mayordomo E, Czerniak BA, Abruzzo LV, Dal Cin P, Araujo DM, Lev DC, López-Terrada D, Lazar AJ: Fluorescence in situ hybridization is a useful ancillary diagnostic tool for extraskeletal myxoid chondrosarcoma. Mod Pathol; 2008 Nov;21(11):1303-10
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  • [Title] Fluorescence in situ hybridization is a useful ancillary diagnostic tool for extraskeletal myxoid chondrosarcoma.
  • Extraskeletal myxoid chondrosarcoma is a rare soft tissue tumor characterized by a nodular growth pattern with eosinophilic cells usually in a reticular pattern and abundant myxoid stroma.
  • In contrast to other myxoid sarcomas, the majority of extraskeletal myxoid chondrosarcomas harbor a balanced translocation, t(9;22)(q22;q12), that fuses EWSR1 with NR4A3 (also known as CHN).
  • We examined the diagnostic utility of fluorescence in situ hybridization for extraskeletal myxoid chondrosarcoma using the LSI EWSR1 break-apart probe (Abbott Molecular/Vysis, Des Plaines, IL, USA).
  • Sixteen cases of extraskeletal myxoid chondrosarcoma with formalin-fixed paraffin-embedded tissue available were retrieved (1991-2007).
  • In this study, the vast majority of extraskeletal myxoid chondrosarcomas are associated with a rearrangement at the EWSR1 locus (22q12).
  • Fluorescence in situ hybridization is useful to support the diagnosis of extraskeletal myxoid chondrosarcomas and may help to differentiate it from mimics such as other myxoid sarcomas, particularly in limited biopsies.
  • [MeSH-major] Calmodulin-Binding Proteins / genetics. Chondrosarcoma / diagnosis. RNA-Binding Proteins / genetics. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Adult. Aged. Chromosomes, Human, Pair 22. Chromosomes, Human, Pair 9. DNA, Neoplasm / genetics. Diagnosis, Differential. Extremities. Female. Gene Rearrangement. Humans. In Situ Hybridization, Fluorescence. Male. Middle Aged. Sarcoma / diagnosis. Translocation, Genetic

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  • (PMID = 18587326.001).
  • [ISSN] 1530-0285
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Calmodulin-Binding Proteins; 0 / DNA, Neoplasm; 0 / EWSR1 protein, human; 0 / RNA-Binding Proteins
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33. Kwon JW, Choi JA, Kwack KS, Oh JH, Chung JH, Kang HS: Myxoid chondrosarcoma in the calcaneus: a case report with MR imaging findings. Skeletal Radiol; 2007 Jun;36 Suppl 1:S82-5
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  • [Title] Myxoid chondrosarcoma in the calcaneus: a case report with MR imaging findings.
  • Skeletal myxoid chondrosarcoma is an extraordinarily rare neoplasm with a distinct histological morphology.
  • Herein, we report a case of a myxoid chondrosarcoma in the calcaneus of a 20-year-old man with a description of its MR imaging (MRI) and histological findings.
  • [MeSH-major] Calcaneus / pathology. Chondrosarcoma / diagnosis. Magnetic Resonance Imaging. Myxosarcoma / diagnosis
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Humans. Male

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  • (PMID = 17219232.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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34. Kilpatrick SE, Bergman S, Pettenati MJ, Gulley ML: The usefulness of cytogenetic analysis in fine needle aspirates for the histologic subtyping of sarcomas. Mod Pathol; 2006 Jun;19(6):815-9
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  • The study sample included eight Ewing sarcomas, six synovial sarcomas, five rhabdomyosarcomas, two myxoid liposarcomas, and one each of myxoid chondrosarcoma, osteosarcoma, and atypical lipoma.
  • [MeSH-minor] Adolescent. Adult. Aged. Biopsy, Fine-Needle / methods. Child. Child, Preschool. Chromosomes, Human, Pair 11. Chromosomes, Human, Pair 18 / genetics. Chromosomes, Human, Pair 22. Chromosomes, Human, X / genetics. Cytogenetic Analysis / methods. Female. Humans. Male. Middle Aged. Retrospective Studies. Translocation, Genetic

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  • (PMID = 16557276.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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35. de Vreeze RS, de Jong D, Haas RL, Stewart F, van Coevorden F: Effectiveness of radiotherapy in myxoid sarcomas is associated with a dense vascular pattern. Int J Radiat Oncol Biol Phys; 2008 Dec 1;72(5):1480-7
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  • [Title] Effectiveness of radiotherapy in myxoid sarcomas is associated with a dense vascular pattern.
  • The subgroup of myxoid liposarcoma (MLS), a sarcoma with a typical vascular crow's feet pattern, is highly radiosensitive, but a mechanism for this phenomenon is unknown.
  • [MeSH-major] Leiomyosarcoma / pathology. Leiomyosarcoma / radiotherapy. Liposarcoma, Myxoid / pathology. Liposarcoma, Myxoid / radiotherapy
  • [MeSH-minor] Adult. Aged. Chondrosarcoma / classification. Chondrosarcoma / pathology. Chondrosarcoma / radiotherapy. Chondrosarcoma / surgery. Combined Modality Therapy. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / pathology. Neoplasm Staging. Time Factors. Treatment Outcome. Young Adult

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  • (PMID = 18448271.001).
  • [ISSN] 1879-355X
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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36. Canter RJ, Qin LX, Ferrone CR, Maki RG, Singer S, Brennan MF: Why do patients with low-grade soft tissue sarcoma die? Ann Surg Oncol; 2008 Dec;15(12):3550-60
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  • Conversely, of DODR, extremity (47%) and trunk (18%) were the most common sites, but histology was more variable [liposarcoma 35%, malignant fibrous histiocytoma (MFH) 20%, fibrosarcoma 12%, extraskeletal myxoid chondrosarcoma 10%].

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  • (PMID = 18830667.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA047179-09; United States / NCI NIH HHS / CA / P01 CA047179; United States / NCI NIH HHS / CA / P01 CA 047179; United States / NCI NIH HHS / CA / P01 CA047179-09
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS75337; NLM/ PMC2605207
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37. Bartalena T, Rimondi E, Rossi G, Bianchi G, Alberghini M: Low grade central chondrosarcoma of the fifth costotransverse joint. Australas Radiol; 2007 Oct;51 Spec No.:B122-5
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  • [Title] Low grade central chondrosarcoma of the fifth costotransverse joint.
  • Chondrosarcoma (CHS) is the third most frequent primary malignant tumour of bone exceeded only by myeloma and osteosarcoma.
  • Both CT-guided core needle biopsy and excisional biopsy were consistent with grade I central CHS with myxoid change and focal areas of Grade II CHS.
  • [MeSH-major] Chondrosarcoma / diagnosis. Spinal Neoplasms / diagnosis
  • [MeSH-minor] Adult. Female. Humans. Thoracic Vertebrae / pathology. Thoracic Vertebrae / radiography. Thoracic Vertebrae / radionuclide imaging

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  • (PMID = 17875132.001).
  • [ISSN] 0004-8461
  • [Journal-full-title] Australasian radiology
  • [ISO-abbreviation] Australas Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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38. Pai MR, Naik R, Kamath R, Magar D: Myoepithelioma of soft tissue. Indian J Pathol Microbiol; 2009 Jan-Mar;52(1):100-2
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  • With a clinical diagnosis of chondrosarcoma, the tumor with the surrounding tissue was resected in segments at surgery.
  • Histomorphology revealed nests, sheets and cords of round to spindled cells with extensive squamous metaplasia in a myxoid to fibrous stroma.
  • [MeSH-minor] Adult. Female. Humans. Keratins / analysis. Magnetic Resonance Imaging

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  • (PMID = 19136797.001).
  • [ISSN] 0974-5130
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 68238-35-7 / Keratins
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39. Moore LF, Kransdorf MJ, Buskirk SJ, O'Connor MI, Menke DM: Radiation-induced pseudotumor following therapy for soft tissue sarcoma. Skeletal Radiol; 2009 Jun;38(6):579-84
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  • Primary tumors were malignant fibrous histiocytoma (n = 13), leiomyosarcoma (n = 6), liposarcoma (n = 3), synovial sarcoma (n = 1), and extraskeletal chondrosarcoma (n = 1).
  • All lesions were high-grade sarcomas, except for two myxoid liposarcomas.
  • [MeSH-minor] Adult. Aged. Comorbidity. Female. Florida / epidemiology. Humans. Incidence. Male. Middle Aged. Retrospective Studies. Risk Assessment / methods. Risk Factors

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  • (PMID = 19221738.001).
  • [ISSN] 1432-2161
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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40. Bifulco K, De Chiara A, Fazioli F, Longanesi-Cattani I, Cantelmo AR, Tirino V, Apice G, Rocco G, Lombardi ML, Carriero MV: Cell invasiveness in sarcomas: a possibly useful clinical correlation. Tumori; 2008 Jul-Aug;94(4):505-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adolescent. Adult. Aged. Chondrosarcoma / pathology. Collagen. Disease Progression. Disease-Free Survival. Drug Combinations. Female. Fibroma / pathology. Fibrosarcoma / pathology. Humans. Immunohistochemistry. Laminin. Liposarcoma, Myxoid / pathology. Male. Middle Aged. Neoplasm Invasiveness. Predictive Value of Tests. Prognosis. Proteoglycans. Tumor Cells, Cultured

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  • (PMID = 18822686.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Drug Combinations; 0 / Laminin; 0 / Proteoglycans; 119978-18-6 / matrigel; 9007-34-5 / Collagen
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41. O'Brien J, Thornton J, Cawley D, Farrell M, Keohane K, Kaar G, McEvoy L, O'Brien DF: Extraskeletal myxoid chondrosarcoma of the cerebellopontine angle presenting during pregnancy. Br J Neurosurg; 2008 Jun;22(3):429-32
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  • [Title] Extraskeletal myxoid chondrosarcoma of the cerebellopontine angle presenting during pregnancy.
  • Extraskeletal myxoid chondrosarcoma (EMC) is a rare soft-tissue sarcoma, which usually occurs in the lower extremities.
  • The clinical, radiological and pathological findings in extraskeletal myxoid chondrosarcoma, with an origin in the cerebellopontine angle, are described along with the issues associated with management of this tumour presenting acutely in a 26-year-old woman who was 20 weeks pregnant.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cerebellopontine Angle / pathology. Chondrosarcoma / pathology. Pregnancy Complications, Neoplastic / pathology. Sarcoma / pathology
  • [MeSH-minor] Adult. Female. Humans. Pregnancy. Treatment Outcome


42. Kotil K, Bilge T, Olagac V: Primary intradural myxoid chondrosarcoma: a case report and review in the literature. J Neurooncol; 2005 Nov;75(2):169-72
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  • [Title] Primary intradural myxoid chondrosarcoma: a case report and review in the literature.
  • We report the first case in the literature of a primary intradural myxoid chondrosarcoma.
  • We could not identify this lesion as chondrosarcoma in preoperative period.
  • The mass was excised completely and microscopic examination identified a myxomatous chondrosarcoma.
  • But a histological examination revealed primary myxoid chondrosarcoma.
  • This case presents the first case in the literature of an primary spinal intradural myxoid chondrosarcoma.
  • [MeSH-major] Chondrosarcoma, Mesenchymal / diagnosis. Meningeal Neoplasms / diagnosis. Meningeal Neoplasms / pathology. Pia Mater / pathology
  • [MeSH-minor] Adult. Dura Mater / surgery. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Radiography. Time Factors. Treatment Outcome. X-Rays

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  • (PMID = 16283441.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 12
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43. Mroczkowski P, Evert M, Tautenhahn J, Meyer F, Lippert H: [A rare extra-skeletal myxoid chondrosarcoma of the lower leg - is amputation absolutely necessary]. Zentralbl Chir; 2010 Feb;135(1):83-6
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  • [Title] [A rare extra-skeletal myxoid chondrosarcoma of the lower leg - is amputation absolutely necessary].
  • The aim of this case report is to show the management of an extraordinary extra-skeletal myxoid chondrosarcoma based on a case report with references from the literature.
  • Histopathological investigation of a percutaneous biopsy revealed a chondrosarcoma.
  • En-bloc-resection (R 0) of the rear superficial compartment was performed (specimen weight 1 370 g; tumour size 11.5 x 9.5 x 8 cm) leading to the definitive diagnosis of an extra-skeletal myxoid chondrosarcoma.
  • DISCUSSION: The myxoid chondrosarcoma is a rare tumour lesion, and according to the literature, only 2 % occur outside of the skeleton.
  • [MeSH-major] Amputation. Chondrosarcoma / surgery. Leg / surgery. Muscle Neoplasms / surgery
  • [MeSH-minor] Adult. Biopsy. Combined Modality Therapy. Disease Progression. Humans. Magnetic Resonance Imaging. Male. Radiotherapy, Adjuvant

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  • [Copyright] Georg Thieme Verlag Stuttgart, New York.
  • (PMID = 19890812.001).
  • [ISSN] 1438-9592
  • [Journal-full-title] Zentralblatt für Chirurgie
  • [ISO-abbreviation] Zentralbl Chir
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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44. Heyse TJ, Malcherczyk D, Moll R, Timmesfeld N, Wapelhorst J, Fuchs-Winkelmann S, Paletta JR, Schofer MD: CD44: survival and metastasis in chondrosarcoma. Osteoarthritis Cartilage; 2010 Jun;18(6):849-56
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  • [Title] CD44: survival and metastasis in chondrosarcoma.
  • OBJECTIVE: Recent studies have shown abnormal expression of CD44s and some of its isoforms in many human malignancies, but little is known about the presence of CD44 in chondrosarcoma.
  • METHOD: Thirty paraffin-embedded chondrosarcoma samples were immunostained with monoclonal antibodies for CD44s, CD44v5 and CD44v6.
  • RESULTS: Among the 30 patients (median age 50 years) there were 22 conventional chondrosarcomas, two dedifferentiated chondrosarcomas, two extraskeletal chondrosarcomas, and one periostal, mesenchymal, clear cell and myxoid chondrosarcoma each.
  • CONCLUSIONS: Overexpression of CD44s correlated significantly with metastatic potential and with poorer survival in patients with chondrosarcoma.

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  • [Copyright] Copyright 2010 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 20171296.001).
  • [ISSN] 1522-9653
  • [Journal-full-title] Osteoarthritis and cartilage
  • [ISO-abbreviation] Osteoarthr. Cartil.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD44; 0 / Protein Isoforms
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