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1. Xiong Y, Guo H, Zhang S, Zhang B, Li T: [Differences of the molecular phenotypes and the histogenesis between dermatofibroma and dermatofibrosarcoma protuberans]. Beijing Da Xue Xue Bao; 2008 Aug 18;40(4):395-400
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  • DF is a benign tumor, while DFSP a low grade malignant tumor.
  • [MeSH-major] Antigens, CD34 / metabolism. Dermatofibrosarcoma / genetics. Factor XIIIa / metabolism. Histiocytoma, Benign Fibrous / genetics
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Cell Differentiation. Child. Child, Preschool. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Phenotype. Young Adult

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  • (PMID = 18677387.001).
  • [ISSN] 1671-167X
  • [Journal-full-title] Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences
  • [ISO-abbreviation] Beijing Da Xue Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, CD34; EC 2.3.2.13 / Factor XIIIa
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2. Hwang SS, Park SY, Park YH: The CT and F-FDG PET/CT appearance of primary renal malignant fibrous histiocytoma. J Med Imaging Radiat Oncol; 2010 Aug;54(4):365-7
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  • [Title] The CT and F-FDG PET/CT appearance of primary renal malignant fibrous histiocytoma.
  • Renal malignant fibrous histiocytoma (MFH) is a rare, primary renal tumour.
  • [MeSH-major] Fluorodeoxyglucose F18. Histiocytoma, Malignant Fibrous / diagnosis. Kidney Neoplasms / diagnosis. Positron-Emission Tomography / methods. Radiopharmaceuticals. Tomography, X-Ray Computed / methods
  • [MeSH-minor] Adult. Follow-Up Studies. Humans. Kidney / radiography. Kidney / radionuclide imaging. Kidney / surgery. Male

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  • (PMID = 20718917.001).
  • [ISSN] 1754-9485
  • [Journal-full-title] Journal of medical imaging and radiation oncology
  • [ISO-abbreviation] J Med Imaging Radiat Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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3. Gong LH, Sun XQ, Meng SQ, Huang XY: [Giant cell tumor of bone and malignancies in giant cell tumor: a clinicopathologic analysis]. Zhonghua Bing Li Xue Za Zhi; 2009 May;38(5):312-5
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  • Six of the 13 cases represented concurrent malignancy in giant cell tumor while the remaining 7 cases was malignant transformation in recurrent giant cell tumor.
  • In malignant transformation of recurrent giant cell tumor, the original tumor was giant cell tumor and the recurrence showed features reminiscent of malignant fibrous histiocytoma.
  • The entities need to be distinguished from other giant cell-rich tumors including primary malignant fibrous histiocytoma and giant cell osteosarcoma.
  • [MeSH-major] Bone Neoplasms / pathology. Cell Transformation, Neoplastic. Giant Cell Tumor of Bone / pathology. Histiocytoma, Malignant Fibrous / pathology. Neoplasms, Second Primary / pathology
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Osteosarcoma / pathology. Sarcoma / pathology. Young Adult

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  • (PMID = 19575873.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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4. Shukla R, Pooja B, Radhika S, Nijhawan R, Rajwanshi A: Fine-needle aspiration cytology of extramammary neoplasms metastatic to the breast. Diagn Cytopathol; 2005 Apr;32(4):193-7
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  • Fifteen cases of metastatic breast neoplasms were encountered constituting 1.47% of all malignant tumors of the breast diagnosed on FNA.
  • The adult cases included two cases each of melanoma, small-cell carcinoma, and myeloma; one case of choriocarcinoma; and three cases of soft-tissue sarcomas.
  • These included two cases of malignant fibrous histiocytoma (MFH) and one case of leiomyosarcoma.
  • [MeSH-minor] Adolescent. Adult. Biopsy, Fine-Needle. Child. Female. Humans. Male. Middle Aged. Neoplasm Metastasis / pathology. Predictive Value of Tests

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  • [Copyright] Copyright 2005 Wiley-Liss, Inc.
  • (PMID = 15754368.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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5. Kim MS, Cho WH, Song WS, Lee SY, Jeon DG: Prognostic significance of ezrin expression in pleomorphic malignant fibrous histiocytoma. Anticancer Res; 2007 Mar-Apr;27(2):1171-8
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  • [Title] Prognostic significance of ezrin expression in pleomorphic malignant fibrous histiocytoma.
  • BACKGROUND: Newly defined pleomorphic malignant fibrous histiocytoma represents a pleomorphic sarcoma which shows no definable line of differentiation.
  • [MeSH-major] Cytoskeletal Proteins / biosynthesis. Histiocytoma, Malignant Fibrous / metabolism
  • [MeSH-minor] Adult. Aged. Female. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Staging. Prognosis. Survival Rate


6. Curry WT Jr, Cosgrove GR, Hochberg FH, Loeffler J, Zervas NT: Stereotactic interstitial radiosurgery for cerebral metastases. J Neurosurg; 2005 Oct;103(4):630-5
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  • Primary tumors included lung (33 patients), melanoma (15 patients), renal cell (five patients), breast (two patients), esophageal (two patients), colon (one patient), and Merkle cell (one patient) cancers, and malignant fibrous histiocytoma (one patient).
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Brachytherapy. Female. Humans. Male. Middle Aged. Retrospective Studies. Survival Analysis

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  • (PMID = 16266044.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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7. Visuri T, Pulkkinen P, Paavolainen P: Malignant tumors at the site of total hip prosthesis. Analytic review of 46 cases. J Arthroplasty; 2006 Apr;21(3):311-23
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  • [Title] Malignant tumors at the site of total hip prosthesis. Analytic review of 46 cases.
  • During the years 1974 to 2003, a total of 46 cases of malignant tumors at the site of total hip arthroplasty, 41 sarcomas, 4 lymphomas, and 1 epidermoid carcinoma, have been reported in the Western literature.
  • Malignant fibrous histiocytoma was the most common in 20 (65%) of all soft tissue sarcomas.
  • The patients with malignant tumors had been operated on more often for secondary osteoarthritis and had more local complications than those in ordinary total hip arthroplasty series.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Arthroplasty, Replacement, Hip. Bone Neoplasms. Carcinoma, Squamous Cell. Female. Humans. Incidence. Lymphoma, Non-Hodgkin. Male. Middle Aged. Osteoarthritis, Hip / surgery. Postoperative Complications. Prosthesis Design. Reoperation. Risk Factors. Soft Tissue Neoplasms / therapy

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  • (PMID = 16627137.001).
  • [ISSN] 0883-5403
  • [Journal-full-title] The Journal of arthroplasty
  • [ISO-abbreviation] J Arthroplasty
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 89
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8. Perez EA, Gutierrez JC, Moffat FL Jr, Franceschi D, Livingstone AS, Spector SA, Levi JU, Sleeman D, Koniaris LG: Retroperitoneal and truncal sarcomas: prognosis depends upon type not location. Ann Surg Oncol; 2007 Mar;14(3):1114-22
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  • The most common tumor types were liposarcoma (35.9%), leiomyosarcoma (30.1%), and malignant fibrous histiocytoma (MFH) (19.5%).
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Extremities / pathology. Female. Fibrosarcoma / drug therapy. Fibrosarcoma / pathology. Fibrosarcoma / surgery. Histiocytoma, Benign Fibrous / drug therapy. Histiocytoma, Benign Fibrous / pathology. Histiocytoma, Benign Fibrous / surgery. Humans. Leiomyosarcoma / drug therapy. Leiomyosarcoma / pathology. Leiomyosarcoma / surgery. Liposarcoma / drug therapy. Liposarcoma / pathology. Liposarcoma / surgery. Male. Middle Aged. Prognosis. Retrospective Studies. Risk Factors. Survival Rate. Time Factors

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  • (PMID = 17206483.001).
  • [ISSN] 1068-9265
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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9. Fayda M, Aksu G, Yaman Agaoglu F, Karadeniz A, Darendeliler E, Altun M, Hafiz G: The role of surgery and radiotherapy in treatment of soft tissue sarcomas of the head and neck region: review of 30 cases. J Craniomaxillofac Surg; 2009 Jan;37(1):42-8
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  • BACKGROUND: Thirty adult patients with head and neck soft tissue sarcoma (HNSTS) treated between 1987 and 2000 were retrospectively analysed.
  • PATIENTS AND METHODS: The most frequent histopathological subtypes were chondrosarcomas (27%) and malignant fibrous histiocytoma (20%).
  • [MeSH-minor] Adult. Aged. Bone Neoplasms / radiotherapy. Bone Neoplasms / surgery. Chemotherapy, Adjuvant. Chondrosarcoma / radiotherapy. Chondrosarcoma / surgery. Disease-Free Survival. Female. Follow-Up Studies. Histiocytoma, Malignant Fibrous / radiotherapy. Histiocytoma, Malignant Fibrous / surgery. Humans. Male. Maxillary Sinus Neoplasms / radiotherapy. Maxillary Sinus Neoplasms / surgery. Middle Aged. Neoplasm Recurrence, Local / prevention & control. Neoplasm, Residual / pathology. Neoplasms, Second Primary / pathology. Nose Neoplasms / radiotherapy. Nose Neoplasms / surgery. Radiotherapy Dosage. Radiotherapy, Adjuvant. Radiotherapy, Conformal. Radiotherapy, High-Energy. Retrospective Studies. Survival Rate. Young Adult

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  • (PMID = 18804382.001).
  • [ISSN] 1010-5182
  • [Journal-full-title] Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
  • [ISO-abbreviation] J Craniomaxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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10. Abou-Jaoude M, El Ali M: Malignant fibrous histiocytoma: a case report and literature review. Int Surg; 2009 Jul-Sep;94(3):196-200
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  • [Title] Malignant fibrous histiocytoma: a case report and literature review.
  • Malignant fibrous histiocytoma (MFH) is the most common soft tissue sarcoma in late adult life.
  • [MeSH-major] Genital Neoplasms, Male / pathology. Genital Neoplasms, Male / surgery. Histiocytoma, Malignant Fibrous / pathology. Histiocytoma, Malignant Fibrous / surgery. Spermatic Cord / pathology

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  • (PMID = 20187510.001).
  • [ISSN] 0020-8868
  • [Journal-full-title] International surgery
  • [ISO-abbreviation] Int Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 50
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11. Häfner HM, Moehrle M, Eder S, Trilling B, Röcken M, Breuninger H: 3D-Histological evaluation of surgery in dermatofibrosarcoma protuberans and malignant fibrous histiocytoma: differences in growth patterns and outcome. Eur J Surg Oncol; 2008 Jun;34(6):680-6
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  • [Title] 3D-Histological evaluation of surgery in dermatofibrosarcoma protuberans and malignant fibrous histiocytoma: differences in growth patterns and outcome.
  • AIMS: To evaluate the microscopic growth pattern of dermatofibrosarcoma protuberans (DFSP) and malignant fibrous histiocytoma (MFH) and the long-term outcome using 3D-histologic surgery with paraffin sections to cover complete margins and to detect subclinical spreads very sensitively.
  • MFH is significantly more malignant.
  • [MeSH-major] Dermatofibrosarcoma / pathology. Dermatofibrosarcoma / surgery. Histiocytoma, Malignant Fibrous / pathology. Histiocytoma, Malignant Fibrous / surgery. Imaging, Three-Dimensional. Mohs Surgery. Skin Neoplasms / pathology. Skin Neoplasms / surgery
  • [MeSH-minor] Adult. Disease-Free Survival. Female. Humans. Kaplan-Meier Estimate. Male. Middle Aged. Neoplasm Recurrence, Local. Prospective Studies. Retrospective Studies

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  • (PMID = 17716851.001).
  • [ISSN] 1532-2157
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
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12. Gladdy RA, Qin LX, Moraco N, Edgar MA, Antonescu CR, Alektiar KM, Brennan MF, Singer S: Do radiation-associated soft tissue sarcomas have the same prognosis as sporadic soft tissue sarcomas? J Clin Oncol; 2010 Apr 20;28(12):2064-9
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  • A matched-cohort analysis was performed for radiation-associated and sporadic malignant fibrous histiocytoma (MFH).
  • DSS was significantly worse in primary RAS malignant peripheral nerve sheath tumors (MPNSTs) compared with unmatched sporadic MPNSTs (P = .001).


13. Al-Daraji W, Anandan A, Klassen-Fischer M, Auerbach A, Marwaha JS, Fanburg-Smith JC: Soft tissue Rosai-Dorfman disease: 29 new lesions in 18 patients, with detection of polyomavirus antigen in 3 abdominal cases. Ann Diagn Pathol; 2010 Oct;14(5):309-16
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  • Initial pathologic diagnosis ranged from Rosai-Dorfman disease or inflammatory pseudotumor to inflammatory malignant fibrous histiocytoma.
  • [MeSH-minor] Abdomen. Adolescent. Adult. Aged. Aged, 80 and over. Child. Female. Humans. Male. Middle Aged. S100 Proteins / metabolism. Simian virus 40 / isolation & purification

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  • [Copyright] Copyright © 2010. Published by Elsevier Inc.
  • (PMID = 20850691.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Viral, Tumor; 0 / S100 Proteins
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14. Datir A, James SL, Ali K, Lee J, Ahmad M, Saifuddin A: MRI of soft-tissue masses: the relationship between lesion size, depth, and diagnosis. Clin Radiol; 2008 Apr;63(4):373-8; discussion 379-80
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  • AIMS: To identify the relationship between depth and size of soft-tissue mass lesions relative to histological diagnosis in a range of malignant neoplastic, benign neoplastic, and non-neoplastic conditions on magnetic resonance imaging (MRI).
  • The mean age was 54.1 years for malignant neoplastic lesions compared with 40.1 years for benign neoplastic and 45.4 years for non-neoplastic conditions.
  • There was a significant age difference when malignant lesions were compared with benign neoplastic and non-neoplastic lesions (p<0.001).
  • No significant relationship was present between lesion depth (480 deep, 91 superficial) and diagnosis (288 malignant neoplastic, 197 benign neoplastic and 86 non-neoplastic lesions).
  • The current study suggests that relationship to fascia is less important as a predictor of malignant potential in a patient cohort treated at a supra-regional centre.
  • [MeSH-minor] Abscess / diagnosis. Abscess / pathology. Adolescent. Adult. Age Factors. Aged. Aged, 80 and over. Child. Child, Preschool. Female. Fibroma / diagnosis. Fibroma / pathology. Ganglion Cysts / diagnosis. Ganglion Cysts / pathology. Hemangioma / diagnosis. Hemangioma / pathology. Histiocytoma, Malignant Fibrous / diagnosis. Histiocytoma, Malignant Fibrous / pathology. Humans. Lipoma / diagnosis. Lipoma / pathology. Liposarcoma / diagnosis. Liposarcoma / pathology. Magnetic Resonance Imaging. Male. Middle Aged. Myositis Ossificans / diagnosis. Myositis Ossificans / pathology. Prospective Studies. Risk Factors. Sarcoma, Synovial / diagnosis. Sarcoma, Synovial / pathology

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  • (PMID = 18325355.001).
  • [ISSN] 0009-9260
  • [Journal-full-title] Clinical radiology
  • [ISO-abbreviation] Clin Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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15. Kinoglou G, Gebhart M, Burette R, de Saint-Aubain N: Myxofibrosarcoma involving the external saphenous nerve: a case report. Acta Chir Belg; 2007 Jul-Aug;107(4):442-5
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  • Myxofibrosarcoma, also known as "myxoid malignant fibrous histiocytoma" is one of the most common soft tissue sarcomas in the extremities of adult patients.

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  • (PMID = 17966544.001).
  • [ISSN] 0001-5458
  • [Journal-full-title] Acta chirurgica Belgica
  • [ISO-abbreviation] Acta Chir. Belg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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16. Brahmakulam LE, Noronha BE: Malignant fibrous histiocytoma of the mandible. Ear Nose Throat J; 2010 Oct;89(10):E1-4
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  • [Title] Malignant fibrous histiocytoma of the mandible.
  • Malignant fibrous histiocytoma (MFH) of the mandible is rare.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / surgery. Mandibular Neoplasms / surgery
  • [MeSH-minor] Adult. Fatal Outcome. Female. Humans. Immunohistochemistry. Lung Neoplasms / secondary. Surgical Flaps

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  • (PMID = 20981646.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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17. Muehling BM, Toelkes S, Schelzig H, Barth TF, Sunder-Plassmann L: Tyrosine kinase expression in pulmonary metastases and paired primary tumors. Interact Cardiovasc Thorac Surg; 2010 Feb;10(2):228-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Tissue specimen from 35 lung metastases of 33 patients with renal cell carcinoma (n=8), sarcoma (n=10), colorectal carcinoma (n=6), otolaryngologic carcinoma (OLC, n=4), testicular and endometrial cancer (n=1 each), malignant melanoma (n=1), adrenal cancer (n=2), malignant fibrous histiocytoma and malignant peripheral nerve sheath tumor (n=1 each) have been immunohistochemically tested for the expression of PDGFR alpha/beta, VEGFR and EGFR.
  • [MeSH-minor] Adolescent. Adult. Aged. Angiogenesis Inhibitors / therapeutic use. Female. Humans. Immunohistochemistry. Male. Middle Aged. Protein Kinase Inhibitors / therapeutic use. Receptor, Epidermal Growth Factor / analysis. Receptor, Platelet-Derived Growth Factor alpha / analysis. Receptor, Platelet-Derived Growth Factor beta / analysis. Receptors, Vascular Endothelial Growth Factor / analysis. Young Adult

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  • (PMID = 19948538.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Angiogenesis Inhibitors; 0 / Biomarkers, Tumor; 0 / Protein Kinase Inhibitors; EC 2.7.10.1 / EGFR protein, human; EC 2.7.10.1 / Protein-Tyrosine Kinases; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; EC 2.7.10.1 / Receptor, Platelet-Derived Growth Factor alpha; EC 2.7.10.1 / Receptor, Platelet-Derived Growth Factor beta; EC 2.7.10.1 / Receptors, Vascular Endothelial Growth Factor
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18. Pu LL: Reconstruction of a large gluteal soft-tissue defect with the double-opposing V-Y fasciocutaneous advancement flap. Plast Reconstr Surg; 2007 Feb;119(2):599-603
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / surgery. Liposarcoma / surgery. Soft Tissue Neoplasms / surgery. Surgical Flaps. Wounds and Injuries / surgery
  • [MeSH-minor] Adult. Buttocks. Female. Humans. Male. Middle Aged. Reconstructive Surgical Procedures. Surgical Wound Infection / surgery

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  • (PMID = 17230096.001).
  • [ISSN] 1529-4242
  • [Journal-full-title] Plastic and reconstructive surgery
  • [ISO-abbreviation] Plast. Reconstr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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19. Sawaed S, Adler AC, Vlodavsky E, Bar-Sela G: Primary cardiac chondrosarcoma with rapid MFH-like recurrence: case report and review of tumor type. Tumori; 2010 Jul-Aug;96(4):637-9
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  • [MeSH-minor] Chemotherapy, Adjuvant. Diagnosis, Differential. Echocardiography. Histiocytoma, Malignant Fibrous / diagnosis. Humans. Male. Young Adult

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  • (PMID = 20968149.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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20. Li WX, Ye ZM, Yang DS, Tao HM, Lin N, Yang ZM: [Endoprosthetic reconstruction after wide resection of primary bone tumor around the knee]. Zhonghua Wai Ke Za Zhi; 2007 May 15;45(10):665-8
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  • All the diagnoses were pathologically confirmed (58 patients with osteosarcoma, 2 with osteosarcomatosis, 1 with parosteal osteosarcoma, 4 with malignant fibrous histiocytoma, 13 with giant cell tumor of bone, 1 with leiomyosarcoma, 2 with Ewing's sarcoma, 2 with chondrosarcoma).
  • [MeSH-minor] Adolescent. Adult. Child. Female. Follow-Up Studies. Humans. Limb Salvage. Male. Middle Aged. Retrospective Studies. Treatment Outcome

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  • (PMID = 17688816.001).
  • [ISSN] 0529-5815
  • [Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]
  • [ISO-abbreviation] Zhonghua Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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21. Padula GD, Schmitz M: Adult paratesticular malignant fibrous histiocytoma treated with surgery, systemic chemotherapy and postoperative adjuvant radiotherapy. J Cancer Res Ther; 2006 Oct-Dec;2(4):201-2
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  • [Title] Adult paratesticular malignant fibrous histiocytoma treated with surgery, systemic chemotherapy and postoperative adjuvant radiotherapy.
  • Paratesticular malignant fibrous histiocytoma is an extremely rare malignancy of the scrotum.
  • We present here a case of a 57-year-old man with a diagnosis of high-grade malignant fibrous histiocytoma of the left intrascrotal region who underwent radical orchiectomy, systemic chemotherapy and postoperative radiotherapy.
  • [MeSH-major] Genital Neoplasms, Male / therapy. Histiocytoma, Malignant Fibrous / therapy. Scrotum / radiation effects

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  • (PMID = 17998705.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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22. Mizukami H, Yajima N, Wada R, Matsumoto K, Kojima M, Klöppel G, Yagihashi S: Pancreatic malignant fibrous histiocytoma, inflammatory myofibroblastic tumor, and inflammatory pseudotumor related to autoimmune pancreatitis: characterization and differential diagnosis. Virchows Arch; 2006 May;448(5):552-60
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  • [Title] Pancreatic malignant fibrous histiocytoma, inflammatory myofibroblastic tumor, and inflammatory pseudotumor related to autoimmune pancreatitis: characterization and differential diagnosis.
  • Malignant fibrous histiocytoma (MFH) and inflammatory myofibroblastic tumor (IMT) are uncommon primary non-epithelial cell tumors of the pancreas.
  • [MeSH-major] Granuloma, Plasma Cell / pathology. Histiocytoma, Malignant Fibrous / pathology. Neoplasms, Muscle Tissue / pathology. Pancreatic Neoplasms / pathology. Pancreatitis / pathology
  • [MeSH-minor] Adult. Autoimmune Diseases / complications. Base Sequence. Diagnosis, Differential. Female. Gene Expression. Gene Expression Profiling. Humans. Immunohistochemistry. Ki-67 Antigen / metabolism. Male. Middle Aged. Mutation. Pancreatectomy. Polymerase Chain Reaction. Tumor Suppressor Protein p53 / genetics. Tumor Suppressor Protein p53 / metabolism


23. Li CP, Wang YR, Zhou JC: [Leiomyosarcoma of mediastinum: report of a cases]. Zhonghua Bing Li Xue Za Zhi; 2007 Jan;36(1):58
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  • [MeSH-minor] Actins / metabolism. Adult. Desmin / metabolism. Diagnosis, Differential. Histiocytoma, Malignant Fibrous / pathology. Humans. Immunohistochemistry. Leiomyoma / pathology. Male. Vimentin / metabolism

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  • (PMID = 17374242.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Actins; 0 / Desmin; 0 / Vimentin
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24. Campanacci DA, Scoccianti G, Beltrami G, Mugnaini M, Capanna R: Ankle arthrodesis with bone graft after distal tibia resection for bone tumors. Foot Ankle Int; 2008 Oct;29(10):1031-7
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  • MATERIALS AND METHODS: Resection of the distal tibia and reconstruction by ankle fusion using non-vascularized structural bone grafts was performed in 8 patients affected by malignant (5 patients) or aggressive benign (3 patients) tumors.
  • [MeSH-minor] Adolescent. Adult. Aged. Bone Nails. Bone Plates. Female. Fibula / transplantation. Follow-Up Studies. Giant Cell Tumor of Bone / surgery. Hemangioendothelioma / surgery. Histiocytoma, Benign Fibrous / surgery. Humans. Ilium / transplantation. Limb Salvage. Male. Middle Aged. Pain Measurement. Postoperative Complications. Retrospective Studies. Sarcoma / surgery. Transplantation, Autologous. Transplantation, Homologous. Treatment Outcome

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  • (PMID = 18851821.001).
  • [ISSN] 1071-1007
  • [Journal-full-title] Foot & ankle international
  • [ISO-abbreviation] Foot Ankle Int
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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25. Papagelopoulos PJ, Mavrogenis AF, Galanis EC, Chloros GD, Papaparaskeva KT: Malignant fibrous histiocytoma of bone associated with type-1 neurofibromatosis. A case report. J Bone Joint Surg Am; 2005 Feb;87(2):399-403
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  • [Title] Malignant fibrous histiocytoma of bone associated with type-1 neurofibromatosis. A case report.
  • [MeSH-major] Bone Neoplasms / pathology. Femur / pathology. Histiocytoma, Benign Fibrous / pathology. Neurofibromatosis 1 / pathology
  • [MeSH-minor] Adult. Cell Transformation, Neoplastic. Humans. Male


26. Maheshwari R: Review of orbital exenteration from an eye care centre in Western India. Orbit; 2010 Feb;29(1):35-8
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  • Except for one case all exenteration were for malignant neoplasm.
  • Histopathological classification of the neoplasm were sebaceous carcinoma (4 cases), basal cell carcinoma (3 cases), squamous cell carcinoma (3 cases), adenoid cystic carcinoma (1 case), transitional cell carcinoma (1 case), malignant fibrous histiocytoma (1 case), lymphoma (1 case) and mucormycosis (1 case).
  • CONCLUSION: Majority of exenterations performed were for neglected ocular or adnexal malignant lesions that could have been avoided provided patients reported earlier for treatment.
  • [MeSH-minor] Adult. Age Distribution. Aged. Female. Humans. India. Male. Middle Aged. Retrospective Studies. Young Adult

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  • (PMID = 20302408.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 20
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27. Nakayama R, Sato Y, Masutani M, Ogino H, Nakatani F, Chuman H, Beppu Y, Morioka H, Yabe H, Hirose H, Sugimura H, Sakamoto H, Ohta T, Toyama Y, Yoshida T, Kawai A: Association of a missense single nucleotide polymorphism, Cys1367Arg of the WRN gene, with the risk of bone and soft tissue sarcomas in Japan. Cancer Sci; 2008 Feb;99(2):333-9
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  • Bone and soft tissue sarcomas (BSTSs) are rare malignant tumors of mesenchymal origin.
  • An exploratory subgroup analysis without multiple comparison adjustment suggested that the WRN-Cys1367Arg SNP is associated with soft tissue sarcomas, sarcomas with reciprocal chromosomal translocations and malignant fibrous histiocytoma.
  • [MeSH-minor] Adult. Alleles. Base Sequence. Case-Control Studies. Female. Genetic Predisposition to Disease. Genotype. Humans. Japan. Male. Middle Aged. Molecular Sequence Data

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  • (PMID = 18271933.001).
  • [ISSN] 1349-7006
  • [Journal-full-title] Cancer science
  • [ISO-abbreviation] Cancer Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 94ZLA3W45F / Arginine; EC 3.1.- / Exodeoxyribonucleases; EC 3.6.1.- / WRN protein, human; EC 3.6.4.12 / RecQ Helicases; K848JZ4886 / Cysteine
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28. Tirado-Sánchez A, Leon-Dorantes G: Paraneoplastic pemphigus associated with malignant fibrous histiocytoma. Int J Dermatol; 2006 Nov;45(11):1374-5
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  • [Title] Paraneoplastic pemphigus associated with malignant fibrous histiocytoma.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / complications. Paraneoplastic Syndromes / etiology. Pemphigus / etiology
  • [MeSH-minor] Adult. Fluorescent Antibody Technique, Direct. Humans. Immunoglobulin G / analysis. Male. Skin / immunology. Skin / pathology

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  • (PMID = 17076733.001).
  • [ISSN] 0011-9059
  • [Journal-full-title] International journal of dermatology
  • [ISO-abbreviation] Int. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Immunoglobulin G
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29. Al-Daraji WI, Makhlouf HR, Miettinen M, Montgomery EA, Goodman ZD, Marwaha JS, Fanburg-Smith JC: Primary gallbladder sarcoma: a clinicopathologic study of 15 cases, heterogeneous sarcomas with poor outcome, except pediatric botryoid rhabdomyosarcoma. Am J Surg Pathol; 2009 Jun;33(6):826-34
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  • RESULT: PGBS occurred in 4 males and 11 females with the adult median age of 68.5 (range: 24 to 88 y, n=12) and 3 children ages 1.5 to 3 years, the latter all with botryoid embryonal rhabdomyosarcoma.
  • PGBSs were diagnosed as 7 myxofibrosarcomas [malignant fibrous histiocytoma, storiform pleomorphic to myxoid, 2 with an unusual fibromyxoid sarcoma-like (Evans-like), and pleomorphic hyalinizing angiectatic tumor-like mixture], 2 leiomyosarcomas, 1 gastrointestinal stromal tumor-like (GIST-like), 3 botryoid embryonal rhabdomyosarcomas (RMS), and 2 epithelioid angiosarcomas.
  • A variety of sarcoma types are found, yet malignant fibrous histiocytoma is the predominant variant, more common than LMS.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Child, Preschool. Female. Humans. Immunohistochemistry. Infant. Male. Middle Aged. Prognosis

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  • (PMID = 19194282.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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30. Cardona DM, Knapik JA, Reith JD: Dedifferentiated parosteal osteosarcoma with giant cell tumor component. Skeletal Radiol; 2008 Apr;37(4):367-71
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  • Dedifferentiated parosteal osteosarcoma is characterized histologically by the admixture of low-grade fibroblastic osteosarcoma and a high-grade component typically resembling conventional osteosarcoma or malignant fibrous histiocytoma.
  • [MeSH-minor] Adult. Biopsy, Needle. Diagnosis, Differential. Fatal Outcome. Humans. Magnetic Resonance Imaging. Male. Phenotype. Tomography, Emission-Computed

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  • (PMID = 18256826.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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31. Wang CH, Yu HY, Chi NS, Chen YS, Lee KK, Cheng YJ, Lin LC, Tseng WY, Wang SS: Complete excision of primary cardiac malignant fibrous histiocytoma involving the left atrial free wall and mitral annulus by modified autotransplantation. J Thorac Cardiovasc Surg; 2006 Mar;131(3):731-3
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  • [Title] Complete excision of primary cardiac malignant fibrous histiocytoma involving the left atrial free wall and mitral annulus by modified autotransplantation.
  • [MeSH-major] Heart Atria. Heart Neoplasms / surgery. Heart Transplantation. Histiocytoma, Benign Fibrous / surgery. Mitral Valve
  • [MeSH-minor] Adult. Humans. Male

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  • (PMID = 16515932.001).
  • [ISSN] 1097-685X
  • [Journal-full-title] The Journal of thoracic and cardiovascular surgery
  • [ISO-abbreviation] J. Thorac. Cardiovasc. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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32. Sebenik M, Ricci A Jr, DiPasquale B, Mody K, Pytel P, Jee KJ, Knuutila S, Scholes J: Undifferentiated intimal sarcoma of large systemic blood vessels: report of 14 cases with immunohistochemical profile and review of the literature. Am J Surg Pathol; 2005 Sep;29(9):1184-93
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  • Intimal sarcoma (IS) is defined as a malignant tumor arising in the tunica intima of large blood vessels.
  • Histopathology was that of a largely necrotic, poorly differentiated epithelioid and pleomorphic malignant neoplasm relating to the tunica intima.
  • Such extravascular tumors assumed a variety of patterns reminiscent of undifferentiated pleomorphic sarcoma (UPS; in older literature also known as pleomorphic malignant fibrous histiocytoma, MFH) or other distinct types of sarcomas, including osteosarcoma, angiosarcoma, and rhabdomyosarcoma.
  • Although there are rare long-term survivors, UIS behaves as a fully malignant neoplasm that is almost uniformly associated with metastases and tumor-related death.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Antigens, CD31 / metabolism. Diagnosis, Differential. Female. Gelsolin / metabolism. Humans. Immunohistochemistry. Male. Microfilament Proteins. Microscopy, Electron, Transmission. Middle Aged. Nucleic Acid Hybridization. Receptors, Cytoplasmic and Nuclear / metabolism

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  • (PMID = 16096408.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD31; 0 / FLII protein, human; 0 / Gelsolin; 0 / Microfilament Proteins; 0 / Receptors, Cytoplasmic and Nuclear
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33. Paulino AC, Fowler BZ: Secondary neoplasms after radiotherapy for a childhood solid tumor. Pediatr Hematol Oncol; 2005 Mar;22(2):89-101
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  • From 1956 to 1998, 429 children with a malignant solid tumor were treated at a single radiation oncology facility.
  • There were 14 malignant neoplasms in 13 (3.0%) and 14 benign neoplasms in 11 patients (2.6%).
  • For the 14 malignant neoplasms, the median time interval from initial tumor to second malignancy was 10.1 years.
  • The 14 second malignant neoplasms (SMN) were osteosarcoma in 3, breast carcinoma in 2, melanoma in 2, malignant fibrous histiocytoma in 1, dermatofibrosarcoma in 1, leiomyosarcoma in 1, mucoepidermoid carcinoma in 1, colon cancer in 1, chronic myelogenous leukemia in 1, and basal cell carcinoma in 1.
  • [MeSH-minor] Adolescent. Adult. Cause of Death. Child. Child, Preschool. Female. Follow-Up Studies. Humans. Infant. Male. Radiation Dosage. Retrospective Studies. Survival Rate


34. Hou J, Ji Y, Tan YS, Shi DR, Liu YL, Xu C, Zeng HY: [Sclerosing angiomatoid nodular transformation of spleen: a clinicopathologic study of 10 cases with review of literature]. Zhonghua Bing Li Xue Za Zhi; 2010 Feb;39(2):84-7
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  • It needs to be distinguished from borderline or malignant vascular tumors of spleen.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Splenic Neoplasms / pathology
  • [MeSH-minor] Adult. Antigens, CD31 / metabolism. Antigens, CD34 / metabolism. Antigens, CD8 / metabolism. Diagnosis, Differential. Female. Hemangioendothelioma / metabolism. Hemangioendothelioma / pathology. Hemangiosarcoma / metabolism. Hemangiosarcoma / pathology. Humans. Male. Microscopy, Electron. Middle Aged

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  • (PMID = 20388372.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, CD31; 0 / Antigens, CD34; 0 / Antigens, CD8
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35. An JK, Oh KK: Malignant fibrous histiocytoma of chest wall. Yonsei Med J; 2005 Feb 28;46(1):177-80
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  • [Title] Malignant fibrous histiocytoma of chest wall.
  • Primary malignant fibrous histiocytoma (MFH) of the chest wall is rare.
  • [MeSH-major] Bone Neoplasms / pathology. Histiocytoma, Benign Fibrous / pathology. Ribs / pathology. Soft Tissue Neoplasms / pathology. Thoracic Wall / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans

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  • (PMID = 15744825.001).
  • [ISSN] 0513-5796
  • [Journal-full-title] Yonsei medical journal
  • [ISO-abbreviation] Yonsei Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2823048
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36. Tsukahara T, Kawaguchi S, Torigoe T, Asanuma H, Nakazawa E, Shimozawa K, Nabeta Y, Kimura S, Kaya M, Nagoya S, Wada T, Yamashita T, Sato N: Prognostic significance of HLA class I expression in osteosarcoma defined by anti-pan HLA class I monoclonal antibody, EMR8-5. Cancer Sci; 2006 Dec;97(12):1374-80
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  • In contrast, such prognostic significance of HLA class I expression was not found in 15 patients with malignant fibrous histiocytoma of soft tissue.
  • [MeSH-minor] Adolescent. Adult. Child. Female. Histiocytoma, Malignant Fibrous / immunology. Histiocytoma, Malignant Fibrous / pathology. Histiocytoma, Malignant Fibrous / secondary. Humans. Immunoenzyme Techniques. Lymphocytes, Tumor-Infiltrating / immunology. Male. Middle Aged. Prognosis. RNA, Messenger / genetics. RNA, Messenger / metabolism. RNA, Neoplasm / genetics. RNA, Neoplasm / metabolism. Reverse Transcriptase Polymerase Chain Reaction. Sarcoma / immunology. Sarcoma / metabolism. Sarcoma / secondary. Soft Tissue Neoplasms / immunology. Soft Tissue Neoplasms / metabolism. Soft Tissue Neoplasms / pathology. Survival Rate. T-Lymphocytes, Cytotoxic / immunology. beta 2-Microglobulin / genetics. beta 2-Microglobulin / immunology. beta 2-Microglobulin / metabolism

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  • (PMID = 16995877.001).
  • [ISSN] 1347-9032
  • [Journal-full-title] Cancer science
  • [ISO-abbreviation] Cancer Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Histocompatibility Antigens Class I; 0 / RNA, Messenger; 0 / RNA, Neoplasm; 0 / beta 2-Microglobulin
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37. Botrus G, Sciot R, Debiec-Rychter M: Cutaneous aneurysmal fibrous histiocytoma with a t(12;19)(p12;q13) as the sole cytogenetic anomaly. Cancer Genet Cytogenet; 2006 Jan 15;164(2):155-8
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  • [Title] Cutaneous aneurysmal fibrous histiocytoma with a t(12;19)(p12;q13) as the sole cytogenetic anomaly.
  • We report a case of a 39-year-old woman with a recurrent aneurysmal fibrous histiocytoma of the right lower leg.
  • Our case highlights the importance of distinguishing this recurrent but benign lesion from similarly appearing malignant skin tumors.
  • [MeSH-major] Chromosomes, Human, Pair 19. Chromosomes, Human, Pair 22. Histiocytoma, Benign Fibrous / genetics. Skin Neoplasms / genetics. Translocation, Genetic
  • [MeSH-minor] Adult. Cytogenetic Analysis. Female. Humans. Leg. Proto-Oncogene Proteins / genetics. Proto-Oncogene Proteins c-ets / genetics. Repressor Proteins / genetics. Transcription Factors

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  • (PMID = 16434321.001).
  • [ISSN] 0165-4608
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / ETS translocation variant 6 protein; 0 / Proto-Oncogene Proteins; 0 / Proto-Oncogene Proteins c-ets; 0 / Repressor Proteins; 0 / Transcription Factors; 0 / proto-oncogene protein bcl-3
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38. Guo H, Xiong Y, Nong L, Zhang S, Li T: [Reassessment of the pathological diagnosis in 33 cases of malignant fibrous histiocytoma]. Beijing Da Xue Xue Bao; 2008 Aug 18;40(4):374-9
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  • [Title] [Reassessment of the pathological diagnosis in 33 cases of malignant fibrous histiocytoma].
  • OBJECTIVE: Since malignant fibrous histiocytoma (MFH) may be taken as an undifferentiated pleomorphic sarcoma (UPS), this study was conducted to reassess 33 previously diagnosed MFH cases in the past 10 years based on the latest WHO concept.
  • RESULTS: Among the 33 cases, 17 cases (51.5%) of MFH had their diagnoses changed, including 5 leiomyosarcomas, 3 malignant peripheral nerve sheath tumors, 1 fibrosarcoma, 1 inflammatory myofibrosarcoma, 1 giant cell tumor and 1 angiomatoid fibrous histiocytoma.
  • Eleven cases (68.8%) variously expressed CD68 (KP1) and 7 cases (43.8%) expressed CD68 (PG-M1), which were much higher than leiomyosarcoma, malignant peripheral nerve sheath tumor and liposarcoma with significant difference.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Humans. Immunohistochemistry. Middle Aged

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  • (PMID = 18677383.001).
  • [ISSN] 1671-167X
  • [Journal-full-title] Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences
  • [ISO-abbreviation] Beijing Da Xue Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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39. O'Sullivan P, O'Dwyer H, Flint J, Munk PL, Muller N: Soft tissue tumours and mass-like lesions of the chest wall: a pictorial review of CT and MR findings. Br J Radiol; 2007 Jul;80(955):574-80
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  • Other lesions encountered include desmoid tumours and malignant fibrous histiocytoma.
  • [MeSH-minor] Adult. Aged. Female. Humans. Male. Middle Aged. Retrospective Studies

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  • (PMID = 16728417.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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40. Inokuchi T, Takiuchi H, Moriwaki Y, Ka T, Takahashi S, Tsutsumi Z, Shima H, Hirota S, Yamamoto T: Retroperitoneal ancient schwannoma presenting as an adrenal incidentaloma: CT and MR findings. Magn Reson Imaging; 2006 Dec;24(10):1389-93
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  • A laparoscopic adrenalectomy was performed under the suspicion of a malignant tumor, such as a malignant fibrous histiocytoma.
  • [MeSH-minor] Abdomen / ultrasonography. Adrenal Gland Neoplasms / pathology. Adrenal Gland Neoplasms / radiography. Adrenal Gland Neoplasms / ultrasonography. Adult. Diagnosis, Differential. Female. Humans

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  • (PMID = 17145411.001).
  • [ISSN] 0730-725X
  • [Journal-full-title] Magnetic resonance imaging
  • [ISO-abbreviation] Magn Reson Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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41. Shintani K, Matsumine A, Kusuzaki K, Matsubara T, Satonaka H, Wakabayashi T, Hoki Y, Uchida A: Expression of hypoxia-inducible factor (HIF)-1alpha as a biomarker of outcome in soft-tissue sarcomas. Virchows Arch; 2006 Dec;449(6):673-81
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  • The expression of HIF-1alpha protein was immunohistochemically determined in 49 specimens of soft-tissue sarcomas including malignant fibrous histiocytoma (29 patients), synovial sarcoma (12 patients), leiomyosarcoma (four patients), and malignant peripheral nerve sheath tumors (four patients).
  • [MeSH-minor] Adult. Aged. Female. Humans. Immunohistochemistry. Ki-67 Antigen / analysis. Male. Middle Aged. Prognosis. Vascular Endothelial Growth Factor A / analysis

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  • (PMID = 17103226.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / HIF1A protein, human; 0 / Hypoxia-Inducible Factor 1, alpha Subunit; 0 / Ki-67 Antigen; 0 / Vascular Endothelial Growth Factor A
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42. Sadri D, Yazdi I: Postradiation malignant fibrous histiocytoma of the maxillary sinus. Arch Iran Med; 2007 Jul;10(3):393-6
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  • [Title] Postradiation malignant fibrous histiocytoma of the maxillary sinus.
  • Malignant fibrous histiocytoma is the most common soft tissue sarcoma in adults.
  • Recent studies have shown that the occurrence of malignant fibrous histiocytoma in the head and neck can follow radiotherapy for the treatment of other tumors.
  • We, herein, report a case of malignant fibrous histiocytoma, which developed 17 years after radiotherapy of a carcinoma in the maxillary sinus.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / diagnosis. Histiocytoma, Malignant Fibrous / etiology. Maxillary Sinus Neoplasms / diagnosis. Maxillary Sinus Neoplasms / etiology. Neoplasms, Radiation-Induced / diagnosis. Radiotherapy / adverse effects
  • [MeSH-minor] Adult. Humans. Male. Time Factors

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  • (PMID = 17604482.001).
  • [ISSN] 1029-2977
  • [Journal-full-title] Archives of Iranian medicine
  • [ISO-abbreviation] Arch Iran Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Iran
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43. Moradi B, Zahlten-Hinguranage A, Lehner B, Zeifang F: The impact of pathological fractures on therapy outcome in patients with primary malignant bone tumours. Int Orthop; 2010 Oct;34(7):1017-23
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  • [Title] The impact of pathological fractures on therapy outcome in patients with primary malignant bone tumours.
  • The primary objective of this study was to investigate the implications of pathological fractures on therapy outcome in patients with primary malignant bone tumours and to determine whether limb salvage can be safely performed.
  • A retrospective analysis of 447 patients with primary malignant bone tumours, treated between 1985 and 2005, was performed.
  • In 52 of the 447 patients, the primary malignant bone tumour was complicated by a pathological fracture.
  • These fractures were more common in malignant fibrous histiocytoma (MFH) of the bone and in the tumour stages IIa/b and III.
  • Pathological fracture in patients with primary malignant bone tumours is a predictor of worse survival and significantly increases mortality risk.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Combined Modality Therapy. Female. Germany / epidemiology. Humans. Male. Middle Aged. Neoplasm Staging. Remission Induction. Retrospective Studies. Survival Rate. Young Adult

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  • (PMID = 20012861.001).
  • [ISSN] 1432-5195
  • [Journal-full-title] International orthopaedics
  • [ISO-abbreviation] Int Orthop
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC2989037
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44. Kim KA, Kim KW, Park SH, Jang SJ, Park MS, Kim PN, Lee MG, Ha HK: Unusual mesenchymal liver tumors in adults: radiologic-pathologic correlation. AJR Am J Roentgenol; 2006 Nov;187(5):W481-9
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  • CONCLUSION: Cross-sectional imaging findings of mesenchymal liver tumors in adults are varied and some may overlap with others or even with more common malignant epithelial tumors.
  • [MeSH-minor] Adult. Angiomyolipoma / pathology. Angiomyolipoma / radiography. Female. Hamartoma / pathology. Hamartoma / radiography. Hemangioendothelioma, Epithelioid / pathology. Hemangioendothelioma, Epithelioid / radiography. Hemangiosarcoma / pathology. Hemangiosarcoma / radiography. Histiocytoma, Malignant Fibrous / pathology. Histiocytoma, Malignant Fibrous / radiography. Humans. Liver Diseases / pathology. Liver Diseases / radiography. Male. Neoplasms, Germ Cell and Embryonal / pathology. Neoplasms, Germ Cell and Embryonal / radiography. Neoplasms, Muscle Tissue / pathology. Neoplasms, Muscle Tissue / radiography. Sarcoma / pathology. Sarcoma / radiography

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  • (PMID = 17056878.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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45. Bölke E, Ruf L, Budach W, Reinecke P, Röhrborn A, Pape H, Schwarz A, Schmitt G, Aul C: Tandem high-dose chemotherapy supported by autologous peripheral blood stem-cell transplantation and radiotherapy for recurrent malignant fibrous histiocytoma. Wien Klin Wochenschr; 2005 Dec;117(23-24):833-6
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  • [Title] Tandem high-dose chemotherapy supported by autologous peripheral blood stem-cell transplantation and radiotherapy for recurrent malignant fibrous histiocytoma.
  • Malignant fibrous histiocytoma (MFH) is a soft-tissue sarcoma created from fibroblast cells and characterized by a high rate of metastasis or recurrence with poor prognosis.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Hematopoietic Stem Cell Transplantation. Histiocytoma, Malignant Fibrous / therapy. Radiotherapy. Soft Tissue Neoplasms / therapy
  • [MeSH-minor] Adult. Combined Modality Therapy. Doxorubicin / administration & dosage. Female. Humans. Ifosfamide / administration & dosage. Thoracic Surgery. Transplantation, Autologous. Treatment Outcome


46. Xu WJ, Hao DP, Liu SE, Yang XD, Li SK: [Radiological diagnosis of primary malignant fibrous histiocytoma of bone]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2006 Feb;28(1):105-9
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  • [Title] [Radiological diagnosis of primary malignant fibrous histiocytoma of bone].
  • OBJECTIVE: To explore the radiological diagnosis of primary malignant fibrous histiocytoma (MFH) of bone.
  • [MeSH-major] Bone Neoplasms / diagnosis. Histiocytoma, Malignant Fibrous / diagnosis. Magnetic Resonance Imaging. Tomography, X-Ray Computed
  • [MeSH-minor] Adult. Aged. Female. Humans. Male. Middle Aged. Retrospective Studies. X-Ray Film


47. Yang WZ, Cui ZY, Zhang W, Zhou HY, Wang QS, Zhang YQ, Shi XQ: [Diagnosis and treatment of primary epididymal tumor: a report of 35 cases]. Zhonghua Nan Ke Xue; 2010 Jun;16(6):527-30
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  • RESULTS: Postoperative pathology confirmed 33 cases of benign tumor (including 21 adenomatoid tumor, 7 leiomyoma, 4 fibroma, and 1 papillary cystadenoma), and 2 cases of malignancy (1 malignant fibrous histiocytoma and 1 adenocarcinoma).
  • [MeSH-minor] Adult. Aged. Humans. Lymph Node Excision. Male. Middle Aged. Retrospective Studies. Treatment Outcome

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  • (PMID = 20608358.001).
  • [ISSN] 1009-3591
  • [Journal-full-title] Zhonghua nan ke xue = National journal of andrology
  • [ISO-abbreviation] Zhonghua Nan Ke Xue
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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48. Dei Tos AP: Classification of pleomorphic sarcomas: where are we now? Histopathology; 2006 Jan;48(1):51-62
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  • Until a decade ago, so-called pleomorphic and storiform malignant fibrous histiocytoma (MFH) represented the most frequently diagnosed sarcoma, accounting for approximately 40% of adult mesenchymal malignancies.
  • With the advent of electron microscopy, immunohistochemistry and molecular genetics, it became clear that the so-called "facultative fibroblast" theory had no scientific grounds and, in 1992, a milestone paper eventually brought attention to the concept that MFH merely represented a morphological pattern shared by a wide variety of poorly differentiated malignant neoplasms, which include specific subtypes of pleomorphic sarcomas.

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  • (PMID = 16359537.001).
  • [ISSN] 0309-0167
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 63
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49. Zhang L, Fan WJ, Zhao M, Wang LG: [CT guided radio frequency ablation as a treatment of pelvis tumor]. Zhonghua Yi Xue Za Zhi; 2009 Aug 4;89(29):2046-9
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  • METHODS: 11 males and 8 females ranging from 25 to 49 years old (average 37) were enrolled in this study, all the 19 patients were suffering from pelvis tumor including giant cell tumor of bone (2/19), Ewing's sarcoma (2/19), malignant fibrous histiocytoma (3/19) and metastatic diseases (12/19).
  • [MeSH-minor] Adult. Female. Follow-Up Studies. Humans. Male. Middle Aged. Treatment Outcome

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  • (PMID = 20017327.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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50. Canter RJ, Qin LX, Ferrone CR, Maki RG, Singer S, Brennan MF: Why do patients with low-grade soft tissue sarcoma die? Ann Surg Oncol; 2008 Dec;15(12):3550-60
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  • Conversely, of DODR, extremity (47%) and trunk (18%) were the most common sites, but histology was more variable [liposarcoma 35%, malignant fibrous histiocytoma (MFH) 20%, fibrosarcoma 12%, extraskeletal myxoid chondrosarcoma 10%].

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  • (PMID = 18830667.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA047179-09; United States / NCI NIH HHS / CA / P01 CA047179; United States / NCI NIH HHS / CA / P01 CA 047179; United States / NCI NIH HHS / CA / P01 CA047179-09
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS75337; NLM/ PMC2605207
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51. Nair V, Weinreb I, MacNeil N, Szollosi Z, Chetty R, Ghazarian D: A unique biphasic variant of cutaneous fibrous histiocytoma with a storiform pattern and intralesional pigmented melanocytes: "storiform melano-fibrous histiocytoma". Eur J Dermatol; 2008 May-Jun;18(3):332-6
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  • [Title] A unique biphasic variant of cutaneous fibrous histiocytoma with a storiform pattern and intralesional pigmented melanocytes: "storiform melano-fibrous histiocytoma".
  • Dermatofibromas (cutaneous fibrous histiocytomas) are common cutaneous neoplasms of mesenchymal origin.
  • There have been reports of a spectrum of melanocytic lesions associated with dermatofibromas ranging from junctional nevi to malignant melanomas, some of which may be coincidentally associated.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adult. Antigens, CD34 / metabolism. Diagnosis, Differential. Factor XIIIa / metabolism. Female. Humans. Immunohistochemistry. In Situ Hybridization, Fluorescence. S100 Proteins / metabolism. Translocation, Genetic / genetics

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  • (PMID = 18474466.001).
  • [ISSN] 1167-1122
  • [Journal-full-title] European journal of dermatology : EJD
  • [ISO-abbreviation] Eur J Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Biomarkers, Tumor; 0 / S100 Proteins; EC 2.3.2.13 / Factor XIIIa
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52. Fabre-Guillevin E, Coindre JM, Somerhausen Nde S, Bonichon F, Stoeckle E, Bui NB: Retroperitoneal liposarcomas: follow-up analysis of dedifferentiation after clinicopathologic reexamination of 86 liposarcomas and malignant fibrous histiocytomas. Cancer; 2006 Jun 15;106(12):2725-33
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  • [Title] Retroperitoneal liposarcomas: follow-up analysis of dedifferentiation after clinicopathologic reexamination of 86 liposarcomas and malignant fibrous histiocytomas.
  • Malignant fibrous histiocytoma (MFH) is no longer considered a homogeneous entity, but rather as the common morphologic appearance of various subtypes of sarcomas.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / pathology. Liposarcoma / pathology. Retroperitoneal Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Cell Differentiation. Disease Progression. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Prognosis. Retrospective Studies. Survival Rate

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  • [Copyright] Copyright 2006 American Cancer Society.
  • (PMID = 16688768.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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53. Canda AE, Sevinc AI, Kocdor MA, Canda T, Balci P, Saydam S, Harmancioglu O: Metastatic tumors in the breast: a report of 5 cases and review of the literature. Clin Breast Cancer; 2007 Jun;7(8):638-43
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  • However, metastases to the breast from nonmammary malignant neoplasms are rare and were detected at a rate of 0.28% in our series.
  • [MeSH-major] Breast Neoplasms / secondary. Carcinoma, Squamous Cell / secondary. Histiocytoma, Malignant Fibrous / secondary. Lymphoma, Large B-Cell, Diffuse / pathology. Sezary Syndrome / pathology
  • [MeSH-minor] Adult. Aged. Female. Humans. Middle Aged. Skin Neoplasms / pathology

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  • (PMID = 17592678.001).
  • [ISSN] 1526-8209
  • [Journal-full-title] Clinical breast cancer
  • [ISO-abbreviation] Clin. Breast Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 25
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54. Ferraresi V, Ciccarese M, Cercato MC, Nuzzo C, Zeuli M, Di Filippo F, Giannarelli D, Cognetti F: Gemcitabine at fixed dose-rate in patients with advanced soft-tissue sarcomas: a mono-institutional phase II study. Cancer Chemother Pharmacol; 2008 Dec;63(1):149-55
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  • PATIENTS AND METHODS: Fourteen patients with advanced locally unresectable and/or metastatic, pretreated STSs (seven leiomyosarcoma, three malignant schwannoma, one synovialsarcoma, one malignant fibrous histiocytoma, one endometrial stromal cell sarcoma, one undifferentiated) were treated with gemcitabine 10 mg/m(2)/min/week over 100 min given for 3 weeks out of 4.
  • [MeSH-minor] Adult. Aged. Combined Modality Therapy. Disease Progression. Dose-Response Relationship, Drug. Female. Gastrointestinal Diseases / chemically induced. Hematologic Diseases / chemically induced. Humans. Male. Middle Aged

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  • (PMID = 18351342.001).
  • [ISSN] 1432-0843
  • [Journal-full-title] Cancer chemotherapy and pharmacology
  • [ISO-abbreviation] Cancer Chemother. Pharmacol.
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase II; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0W860991D6 / Deoxycytidine; B76N6SBZ8R / gemcitabine
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55. Navid F, Willert JR, McCarville MB, Furman W, Watkins A, Roberts W, Daw NC: Combination of gemcitabine and docetaxel in the treatment of children and young adults with refractory bone sarcoma. Cancer; 2008 Jul 15;113(2):419-25
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  • Seventeen patients had osteosarcoma, 2 patients had Ewing sarcoma family of tumors (ESFT), 1 patient had a malignant fibrous histiocytoma (MFH), 1 patient had a chondrosarcoma, and 1 patient had an undifferentiated sarcoma.
  • [MeSH-minor] Adolescent. Adult. Child. Dose-Response Relationship, Drug. Female. Humans. Male. Tomography, X-Ray Computed. Treatment Outcome

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  • [Copyright] (c) 2008 American Cancer Society.
  • (PMID = 18484657.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA21765; United States / NCI NIH HHS / CA / CA23099
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Taxoids; 0W860991D6 / Deoxycytidine; 15H5577CQD / docetaxel; B76N6SBZ8R / gemcitabine
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56. Brinck U, Cordon-Cardo C, Stachura J, Bortkiewicz P, Fischer G, Korabiowska M: Proposal of a new grading system for malignant fibrous histiocytomas. Anticancer Res; 2005 Nov-Dec;25(6B):4293-8
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  • [Title] Proposal of a new grading system for malignant fibrous histiocytomas.
  • The proposed grading system for malignant fibrous histiocytomas (MFH) comprises 3 grades of malignancy.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Female. Humans. Male. Middle Aged. Predictive Value of Tests. Prognosis

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  • (PMID = 16309231.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
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57. Misaki H, Yamauchi T, Arai H, Yamamoto S, Sutoh H, Yoshida A, Tsutani H, Eguchi M, Nagoshi H, Naiki H, Baba H, Ueda T, Yamakawa M: Secondary malignant fibrous histiocytoma following refractory langerhans cell histiocytosis. J Clin Exp Hematop; 2009 May;49(1):33-7
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  • [Title] Secondary malignant fibrous histiocytoma following refractory langerhans cell histiocytosis.
  • We describe a rare case of secondary malignant fibrous histiocytoma (MFH) following Langerhans cell histiocytosis (LCH).
  • [MeSH-major] Histiocytoma, Malignant Fibrous / diagnosis. Histiocytosis, Langerhans-Cell / diagnosis
  • [MeSH-minor] Bone Diseases. Eosinophilic Granuloma / diagnosis. Eosinophilic Granuloma / drug therapy. Eosinophilic Granuloma / radiotherapy. Fatal Outcome. Humans. Lung Diseases. Male. Neoplasms, Second Primary / diagnosis. Neoplasms, Second Primary / etiology. Pneumonia. Salvage Therapy / methods. Young Adult


58. Cullen JW, Jamroz BA, Stevens SL, Madsen W, Hinshaw I, Wilkins RM, Cullen P, Camozzi AB, Fink K, Peck SD, Kelly CM: The value of serial arteriography in osteosarcoma: delivery of chemotherapy, determination of therapy duration, and prediction of necrosis. J Vasc Interv Radiol; 2005 Aug;16(8):1107-19
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  • PURPOSE: To investigate the value of serial arteriography to assess tumor response, predict necrosis, and individualize the duration of a combined intravenous (IV) and intraarterial (IA) neoadjuvant chemotherapy protocol in patients with biopsy-proven high-grade osteosarcoma or malignant fibrohistiocytoma of bone.
  • [MeSH-minor] Adolescent. Adult. Aged. Chemotherapy, Adjuvant. Child. Child, Preschool. Cisplatin / administration & dosage. Doxorubicin / administration & dosage. Female. Histiocytoma, Malignant Fibrous / blood supply. Histiocytoma, Malignant Fibrous / drug therapy. Humans. Infusions, Intra-Arterial. Infusions, Intravenous. Male. Middle Aged. Necrosis. Neovascularization, Pathologic / radiography


59. Xi M, Liu MZ, Wang HX, Cai L, Zhang L, Xie CF, Li QQ: Radiation-induced sarcoma in patients with nasopharyngeal carcinoma: a single-institution study. Cancer; 2010 Dec 1;116(23):5479-86
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  • Fibrosarcoma was the most frequent histologic type observed, followed by osteosarcoma, and malignant fibrous histiocytoma.
  • [MeSH-minor] Adolescent. Adult. Female. Humans. Male. Middle Aged. Prognosis. Time Factors. Treatment Outcome


60. Zhang R, Tan Y, Wang H: [Preliminary evaluation on seroma prevention and treatment with transposition of tissue flaps and arista hemostatic powder]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2006 Dec;20(12):1220-3
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  • OBJECTIVE: To investigate and evaluate prevention and treatment of seroma by transposition of tissue flaps and Arista hemostatic powder after regional lymph node resection in patients with malignant tumors.
  • The metastatic tumors involved the axilla in 1 patient with breast carcinoma, the iliac and inguinal regions in 2 patients with carcinomas of the uterine cervix and the rectum, and the inguinal region in 9 patients, including 4 patients with malignant fibrous histiocytoma(3 in the thigh, 1 in the leg), 2 patients with squamous carcinomas in the leg, 1 patient with synovial sarcoma in the knee, 1 patient with epithelioid sarcoma in the leg, and 1 patient with malignant melanoma in the foot.
  • CONCLUSION: The combined use of transposition of tissue flaps and Arista hemostatic powder spray can effectively prevent or treat seroma after regional lymph node removal in a patient with malignant tumor.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Follow-Up Studies. Humans. Lymph Node Excision / adverse effects. Male. Middle Aged. Surgical Flaps

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  • (PMID = 17228687.001).
  • [ISSN] 1002-1892
  • [Journal-full-title] Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
  • [ISO-abbreviation] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Arista; 9005-25-8 / Starch
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61. Huber GF, Matthews TW, Dort JC: Soft-tissue sarcomas of the head and neck: a retrospective analysis of the Alberta experience 1974 to 1999. Laryngoscope; 2006 May;116(5):780-5
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  • BACKGROUND: Soft-tissue sarcomas (STS) of the head and neck constitute a heterogeneous group of rare malignant tumors occurring in an uncommon site.
  • The most common subtypes of STS in the head and neck are malignant fibrous histiocytoma, dermatofibrosarcoma protuberans, and fibrosarcoma.
  • [MeSH-minor] Adolescent. Adult. Age Distribution. Aged. Aged, 80 and over. Alberta / epidemiology. Biopsy, Needle. Combined Modality Therapy. Female. Humans. Immunohistochemistry. Incidence. Male. Middle Aged. Neoplasm Staging. Predictive Value of Tests. Proportional Hazards Models. Registries. Retrospective Studies. Risk Assessment. Sex Distribution. Survival Analysis

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  • (PMID = 16652087.001).
  • [ISSN] 0023-852X
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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62. Karavasilis V, Seddon BM, Ashley S, Al-Muderis O, Fisher C, Judson I: Significant clinical benefit of first-line palliative chemotherapy in advanced soft-tissue sarcoma: retrospective analysis and identification of prognostic factors in 488 patients. Cancer; 2008 Apr 1;112(7):1585-91
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  • The most common histologic subtypes were leiomyosarcoma (35%) synovial sarcoma (13%), liposarcoma (10%), and malignant fibrous histiocytoma (10%).
  • [MeSH-minor] Adolescent. Adult. Aged. Antineoplastic Combined Chemotherapy Protocols. Bone Neoplasms / drug therapy. Bone Neoplasms / secondary. Chemotherapy, Adjuvant. Female. Follow-Up Studies. Humans. Liver Neoplasms / drug therapy. Liver Neoplasms / secondary. Lung Neoplasms / drug therapy. Lung Neoplasms / secondary. Male. Middle Aged. Neoplasm Staging. Palliative Care. Prognosis. Prospective Studies. Retrospective Studies. Survival Rate

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  • (PMID = 18278813.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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63. Dias AC, Pereira Lde S, Sameshima LM, Reis FA, Vital Filho J: [Malignant fibrous histiocytoma of the eyelid: case report]. Arq Bras Oftalmol; 2009 Jan-Feb;72(1):109-12
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  • [Title] [Malignant fibrous histiocytoma of the eyelid: case report].
  • Fibrous histiocytomas represent 1% of all orbital masses and may be classified into benign, locally aggressive and malignant - these representing nearly 11% of the total.
  • In this study, the authors describe an unusual case of malignant fibrous histiocytoma of the eyelid, discussing clinical and histological features of this neoplasm.
  • [MeSH-major] Eyelid Neoplasms / pathology. Histiocytoma, Malignant Fibrous / pathology
  • [MeSH-minor] Adult. Humans. Male

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  • (PMID = 19347135.001).
  • [ISSN] 1678-2925
  • [Journal-full-title] Arquivos brasileiros de oftalmologia
  • [ISO-abbreviation] Arq Bras Oftalmol
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Brazil
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64. Amico P, Vecchio GM, Bisceglia M, Vasquez E, Magro G: Atypical dermatofibroma with predominant epithelioid/deciduoid-like cell component. Histogenetic considerations in the wide spectrum of fibrohistiocytic dermal tumours. Pathologica; 2010 Jun;102(3):115-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Histiocytoma, Malignant Fibrous / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Humans. Immunohistochemistry. Male

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  • (PMID = 21171517.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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65. Katabathina VS, Vikram R, Nagar AM, Tamboli P, Menias CO, Prasad SR: Mesenchymal neoplasms of the kidney in adults: imaging spectrum with radiologic-pathologic correlation. Radiographics; 2010 Oct;30(6):1525-40
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  • Benign mesenchymal renal tumors include angiomyolipoma, leiomyoma, hemangioma, lymphangioma, juxtaglomerular cell tumor, renomedullary interstitial cell tumor (medullary fibroma), lipoma, solitary fibrous tumor, and schwannoma.
  • Malignant renal tumors of mesenchymal origin include leiomyosarcoma, rhabdomyosarcoma, angiosarcoma, osteosarcoma, synovial sarcoma, fibrosarcoma, malignant fibrous histiocytoma, and solitary fibrous tumor.
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Humans

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  • [Copyright] © RSNA, 2010.
  • (PMID = 21071373.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
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66. Collini P, Sorensen PH, Patel S, Blay JY, Issels RD, Maki RG, Eriksson M, del Muro XG: Sarcomas with spindle cell morphology. Semin Oncol; 2009 Aug;36(4):324-37
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  • In the days before the term "high-grade undifferentiated pleomorphic sarcoma" came into use, one of the most common sarcoma diagnoses was "malignant fibrous histiocytoma," and before that, in an era before immunohistochemistry, "fibrosarcoma" was used to describe most sarcomas.
  • "Spindle cell" is a descriptive phrase that denotes the cellular shape of many of the sarcomas encountered in the adult population.

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  • (PMID = 19664493.001).
  • [ISSN] 0093-7754
  • [Journal-full-title] Seminars in oncology
  • [ISO-abbreviation] Semin. Oncol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA47179
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Protein Kinase Inhibitors
  • [Number-of-references] 62
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67. Wang J, Chen A, Luo Y: [Surgical management of limb salvage for osteogenic malignant tumors around knees]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2006 Oct;20(10):975-7
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  • [Title] [Surgical management of limb salvage for osteogenic malignant tumors around knees].
  • OBJECTIVE: To probe a satisfactory surgical management of the limb salvage for osteogenic malignant tumors around the knees.
  • METHODS: From January 1989 to December 2001, 42 patients (19 males and 18 females, aged 12-46) with osteogenic malignant tumors around the knees underwent surgical management of the limb salvage, including prosthesis replacement, allogenous bone grafting, and bone cement with adriamycin filled.
  • Based on the pathological examination, osteosarcoma was found in 11 patients, synoviosarcoma in 4 patients, malignant fibrous histiocytoma in 3 patients, and giant cell tumor of the bone in 19 patients.
  • By the Enneking evaluating system, the patients were assessed on their reconstructed limb functions after the reconstructive operation for the musculoskeletal malignant tumors.
  • CONCLUSION: Making an early diagnosis, recognizing the operative indication, choosing the operative method, and performing the preoperative and postoperative chemotherapy and/or radiotherapy are the keys to achieving an ideal limb-salvage surgery for osteogenic malignant tumors around the knees.
  • [MeSH-minor] Adolescent. Adult. Child. Female. Follow-Up Studies. Giant Cell Tumor of Bone / surgery. Humans. Male. Middle Aged. Prosthesis Implantation. Reconstructive Surgical Procedures. Soft Tissue Neoplasms / surgery

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  • (PMID = 17140066.001).
  • [ISSN] 1002-1892
  • [Journal-full-title] Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
  • [ISO-abbreviation] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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68. Abdullgaffar B: Undifferentiated pleomorphic sarcoma (so-called malignant fibrous histiocytoma) of the inferior vena cava with extension into the right atrium. Pathology; 2010 Apr;42(3):298-300
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  • [Title] Undifferentiated pleomorphic sarcoma (so-called malignant fibrous histiocytoma) of the inferior vena cava with extension into the right atrium.
  • [MeSH-major] Heart Atria / pathology. Histiocytoma, Malignant Fibrous / pathology. Vascular Neoplasms / pathology. Vena Cava, Inferior / pathology
  • [MeSH-minor] Adult. Fatal Outcome. Humans. Male


69. Kunimura T, Inagaki T, Matsukawa K, Date Y, Morohoshi T, Okada Y, Kawada T: An autopsy case of mediastinal malignant fibrous histiocytoma completely occluding right pulmonary artery. Int J Cardiol; 2005 Oct 10;104(3):346-7
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  • [Title] An autopsy case of mediastinal malignant fibrous histiocytoma completely occluding right pulmonary artery.
  • [MeSH-major] Arterial Occlusive Diseases / pathology. Histiocytoma, Malignant Fibrous / pathology. Mediastinal Neoplasms / pathology. Pulmonary Artery / pathology
  • [MeSH-minor] Adult. Autopsy. Humans. Male

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  • (PMID = 16186067.001).
  • [ISSN] 0167-5273
  • [Journal-full-title] International journal of cardiology
  • [ISO-abbreviation] Int. J. Cardiol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Ireland
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70. Datarkar A, Hazare VK: Malignant fibrous histiocytoma: a case report. J Maxillofac Oral Surg; 2009 Jun;8(2):196-8
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  • [Title] Malignant fibrous histiocytoma: a case report.
  • Malignant Fibrous Histiocytoma (MFH) is a controversial soft tissue malignancy whose pathogenesis continues to be redefined.
  • It remains the most often used term for soft tissue sarcomas of late adult life.
  • A case of malignant fibrous histiocytoma, which posed a diagnostic difficulty, is presented here.

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  • (PMID = 23139506.001).
  • [ISSN] 0972-8279
  • [Journal-full-title] Journal of maxillofacial and oral surgery
  • [ISO-abbreviation] J Maxillofac Oral Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3453940
  • [Keywords] NOTNLM ; Malignant fibrous histiocytoma (MHF) / Mandible
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71. Carrión López P, Pastor Navarro H, Martínez Ruiz J, Giménez Bachs JM, Donate Moreno MJ, Polo Ruiz L, Pastor Guzmán JM, Martínez Sanchiz C, Ruiz Mondéjar R, Virseda Rodríguez JA: [Spermatic cord sarcomas: current status and report of four cases]. Arch Esp Urol; 2009 Apr;62(3):242-6
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  • METHODS/RESULTS: We review the Spanish and international literature and report 4 new cases: 2 patients with well-differentiated spermatic cord liposarcomas (1 treated by simple tumorectomy), 1 patient with liposarcomatous degeneration of a previously excised atypical lipoma, and 1 patient operated for a malignant retroperitoneal fibrous histiocytoma with subsequent local recurrence in the paratesticular region.
  • [MeSH-minor] Adolescent. Adult. Aged. Humans. Male. Middle Aged. Sarcoma

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  • (PMID = 19554782.001).
  • [ISSN] 0004-0614
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 12
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72. Asavamongkolkul A, Waikakul S, Phimolsarnti R, Kiatisevi P: Functional outcome following excision of a tumour and reconstruction of the distal radius. Int Orthop; 2009 Feb;33(1):203-9
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  • We retrospectively studied the functional and oncological results of 15 patients after reconstruction of the distal radius with osteoarticular allograft or non-vascularised fibular graft following wide excision of an aggressive benign or malignant tumour.
  • [MeSH-major] Bone Neoplasms / surgery. Bone Transplantation / methods. Giant Cell Tumor of Bone / surgery. Histiocytoma, Malignant Fibrous / surgery. Osteosarcoma / surgery. Radius / surgery
  • [MeSH-minor] Adolescent. Adult. Bone Cysts / surgery. Bone Plates. Female. Follow-Up Studies. Humans. Male. Middle Aged. Retrospective Studies. Treatment Outcome. Young Adult

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  • (PMID = 17724593.001).
  • [ISSN] 1432-5195
  • [Journal-full-title] International orthopaedics
  • [ISO-abbreviation] Int Orthop
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC2899238
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73. Chen Q, Li Q: [Primary malignant fibrous histiocytoma of the liver: an analysis of 3 cases]. Zhonghua Gan Zang Bing Za Zhi; 2006 Apr;14(4):313, 317
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  • [Title] [Primary malignant fibrous histiocytoma of the liver: an analysis of 3 cases].
  • [MeSH-major] Histiocytoma, Malignant Fibrous / diagnosis. Liver Neoplasms / diagnosis
  • [MeSH-minor] Adult. Female. Humans. Male. Middle Aged

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  • (PMID = 16635314.001).
  • [ISSN] 1007-3418
  • [Journal-full-title] Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology
  • [ISO-abbreviation] Zhonghua Gan Zang Bing Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
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74. Khalkhali K, Azizi MR, Atighechi S: A fibrous histiocytoma of intermediate malignancy arisen from the parotid gland. Arch Iran Med; 2007 Jan;10(1):100-3
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  • [Title] A fibrous histiocytoma of intermediate malignancy arisen from the parotid gland.
  • The light microscopic and immunohistochemical characteristics of a case of fibrous histiocytoma of intermediate malignancy arising from the parotid gland are presented.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / pathology. Parotid Neoplasms / pathology
  • [MeSH-minor] Adult. Biopsy, Fine-Needle. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Oral Surgical Procedures / methods

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  • (PMID = 17198464.001).
  • [ISSN] 1029-2977
  • [Journal-full-title] Archives of Iranian medicine
  • [ISO-abbreviation] Arch Iran Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Iran
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75. Jain A, Sajeevan KV, Babu KG, Lakshmaiah KC: Chemotherapy in adult soft tissue sarcoma. Indian J Cancer; 2009 Oct-Dec;46(4):274-87
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  • [Title] Chemotherapy in adult soft tissue sarcoma.
  • Newer combinations of docetaxel and gemcitabine appear promising in selected subgroups, especially in leiomyosarcoma and malignant fibrous histiocytoma.
  • [MeSH-minor] Adult. Chemotherapy, Adjuvant. Clinical Trials as Topic. Combined Modality Therapy. Humans. Neoadjuvant Therapy


76. Yu RS, Chen Y, Jiang B, Wang LH, Xu XF: Primary hepatic sarcomas: CT findings. Eur Radiol; 2008 Oct;18(10):2196-205
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  • In this pictorial review, we summarized computed tomography (CT) findings of some relatively common types of hepatic sarcomas, including angiosarcoma, epithelioid hemangioendothelioma (EHE), liposarcoma, undifferentiated embryonal sarcoma (UES), leiomyosarcoma, malignant fibrous histiocytoma (MFH), and carcinosarcoma (including cystadenocarcinosarcoma).
  • [MeSH-minor] Adult. Aged. Child. Female. Humans. Male. Middle Aged

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  • (PMID = 18463872.001).
  • [ISSN] 0938-7994
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 53
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77. Mandong BM, Kidmas AT, Manasseh AN, Echejoh GO, Tanko MN, Madaki AJ: Epidemiology of soft tissue sarcomas in Jos, North Central Nigeria. Niger J Med; 2007 Jul-Sep;16(3):246-9
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  • Kaposi sarcoma (KS), Rhabdomyosarcoma (RMS), Malignant Fibrous Histiocytoma (MFH), and Fibrosarcoma (FS) were the commonest histological subtypes accounting for 69 (25.9%), 63 (23.7%), 56 (21.1%) and 49 (18.4%) respectively; with Rhabdomyosarcoma occurring more in paediatric and adolescent age groups, while the rest subtypes were more prevalent in adults.
  • [MeSH-minor] Adult. Age Distribution. Female. Histiocytoma. Humans. Male. Middle Aged. Nigeria / epidemiology. Prevalence. Retrospective Studies. Rhabdomyosarcoma

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  • (PMID = 17937163.001).
  • [ISSN] 1115-2613
  • [Journal-full-title] Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria
  • [ISO-abbreviation] Niger J Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nigeria
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78. De Cesare A, Fiori E, Burza A, Ciardi A, Bononi M, Izzo L, Volpino P, Cavallaro A, Cangemi V: Malignant fibrous histiocytoma of the breast. Report of two cases and review of the literature. Anticancer Res; 2005 Jan-Feb;25(1B):505-8
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  • [Title] Malignant fibrous histiocytoma of the breast. Report of two cases and review of the literature.
  • Among these tumors, malignant fibrous histiocytoma (MFH) is very rare.
  • [MeSH-major] Breast Neoplasms / diagnosis. Histiocytoma, Benign Fibrous / diagnosis
  • [MeSH-minor] Adult. Aged. Breast / pathology. Female. Fibroblasts / metabolism. Humans. Immunohistochemistry. Lymphatic Metastasis. Mammography. Time Factors

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  • (PMID = 15816619.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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79. Tulchinsky H, Keidar A, Strul H, Goldman G, Klausner JM, Rabau M: Extracolonic manifestations of familial adenomatous polyposis after proctocolectomy. Arch Surg; 2005 Feb;140(2):159-63; discussion 164
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  • Two patients died--one of a huge mesenteric desmoid tumor and the other of an aggressive mesenteric malignant fibrous histiocytoma.
  • [MeSH-minor] Adolescent. Adult. Celecoxib. Colorectal Neoplasms / drug therapy. Colorectal Neoplasms / radiography. Comorbidity. Drug Therapy, Combination. Endoscopy, Digestive System. Female. Fibromatosis, Aggressive / drug therapy. Fibromatosis, Aggressive / radiography. Fibromatosis, Aggressive / surgery. Humans. Male. Middle Aged. Pyrazoles / therapeutic use. Retrospective Studies. Sulfonamides / therapeutic use. Tamoxifen / therapeutic use

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  • (PMID = 15723997.001).
  • [ISSN] 0004-0010
  • [Journal-full-title] Archives of surgery (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Pyrazoles; 0 / Sulfonamides; 094ZI81Y45 / Tamoxifen; JCX84Q7J1L / Celecoxib
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80. Vankalakunti M, Kaur J, Srinivasan R: Cytology of sarcoma metastasizing to the thyroid: a case report. Acta Cytol; 2008 Nov-Dec;52(6):729-32
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  • CASE: A 30-year-old woman who was nown to have malignant fibrous histiocytoma arising in the soft tissues of the medial aspect of the ankle presented with a midline thyroid swelling, firm in consistency and moving with deglutition.
  • FNA smears from the thyroid swelling showed discretely lying and loosely cohesive clusters of malignant cells admixed with benign thyroid follicular cells.
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Biopsy, Fine-Needle. Cytological Techniques. Female. Humans

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  • (PMID = 19068681.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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81. Enomoto K, Sakurai K, Amano S, Shiono M: [A case of malignant fibrous histiocytoma (MFH) which produced breast cancer after an operation]. Gan To Kagaku Ryoho; 2008 Nov;35(12):2225-7
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  • [Title] [A case of malignant fibrous histiocytoma (MFH) which produced breast cancer after an operation].
  • Histopathology diagnosis revealed it to be malignant fibrous histiocytoma (MFH).
  • [MeSH-major] Breast Neoplasms / pathology. Histiocytoma, Malignant Fibrous / pathology. Neoplasm Recurrence, Local / pathology
  • [MeSH-minor] Adult. Female. Humans. Magnetic Resonance Imaging. Mastectomy. Tomography, X-Ray Computed


82. Demiralp B, Erler K, Ozturan EK, Bek D, Ozdemir T, Kurt B: An uncommon presentation of malignant fibrous histiocytoma of the calcaneus. J Am Podiatr Med Assoc; 2007 May-Jun;97(3):218-22
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  • [Title] An uncommon presentation of malignant fibrous histiocytoma of the calcaneus.
  • Malignant fibrous histiocytoma of bone is the osseous counterpart of the tumor in soft tissue.
  • We describe a primary malignant fibrous histiocytoma of the calcaneal bone in a 21-year-old man.
  • [MeSH-major] Bone Neoplasms / pathology. Calcaneus. Histiocytoma, Malignant Fibrous / pathology
  • [MeSH-minor] Adult. Humans. Male

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  • (PMID = 17507531.001).
  • [ISSN] 8750-7315
  • [Journal-full-title] Journal of the American Podiatric Medical Association
  • [ISO-abbreviation] J Am Podiatr Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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83. Choudhury M, Nangia A, Singh SK, Pujani M, Thomas S: Cytohistomorphologic features of malignant fibrous histiocytoma of the breast: a case report. Acta Cytol; 2010 Sep-Oct;54(5 Suppl):985-8
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  • [Title] Cytohistomorphologic features of malignant fibrous histiocytoma of the breast: a case report.
  • BACKGROUND: Malignant mesenchymal tumors constitute < 1% of all malignant neoplasms of the breast.
  • CASE: A case of recurrent primary malignant fibrous histiocytoma (MFH) occurred in the breast in a 32-year-old woman.
  • FNAC was suggestive of malignant mesenchymal tumor, most probably MFH.
  • CONCLUSION: Malignant fibrous histiocytoma of the breast is a rare entity, and a complete clinicopathologic correlation with immunohistochemical profile is essential to arrive at a correct diagnosis and guide appropriate management of the patient.
  • [MeSH-major] Breast Neoplasms / pathology. Histiocytoma, Malignant Fibrous / pathology
  • [MeSH-minor] Adult. Cell Nucleus / pathology. Diagnosis, Differential. Female. Giant Cells / pathology. Humans. Mastectomy

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  • (PMID = 21053583.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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84. Hui AC, Ngan SY, Wong K, Powell G, Choong PF: Preoperative radiotherapy for soft tissue sarcoma: the Peter MacCallum Cancer Centre experience. Eur J Surg Oncol; 2006 Dec;32(10):1159-64
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  • The most common histological diagnoses were malignant fibrous histiocytoma and liposarcoma.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Combined Modality Therapy. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Postoperative Complications. Radiation Injuries. Radiotherapy Dosage. Survival Rate

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  • (PMID = 16765559.001).
  • [ISSN] 0748-7983
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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85. Kurt M, Kilickap S, Aksoy S, Tekuzman G: Malignant fibrous histiocytoma, malignant melanoma and squamous cell carcinoma arising from different areas in an adult. South Med J; 2005 Dec;98(12):1228-9
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  • [Title] Malignant fibrous histiocytoma, malignant melanoma and squamous cell carcinoma arising from different areas in an adult.
  • [MeSH-major] Carcinoma, Squamous Cell / diagnosis. Histiocytoma, Malignant Fibrous / diagnosis. Melanoma / diagnosis. Neoplasms, Second Primary / diagnosis. Skin Neoplasms / diagnosis. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Adult. Humans. Male


86. Hsieh SC, Chen CY, Chan WP: Malignant fibrous histiocytoma of the heart: a case report. Acta Cardiol; 2010 Feb;65(1):85-7
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  • [Title] Malignant fibrous histiocytoma of the heart: a case report.
  • Malignant fibrous histiocytoma (MFH) in the heart is rare.
  • [MeSH-major] Heart Neoplasms / diagnosis. Histiocytoma, Malignant Fibrous / diagnosis
  • [MeSH-minor] Adult. Biopsy. Cardiac Surgical Procedures / methods. Diagnosis, Differential. Echocardiography, Transesophageal. Fatal Outcome. Female. Heart Atria. Humans. Tomography, X-Ray Computed

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  • (PMID = 20306896.001).
  • [ISSN] 0001-5385
  • [Journal-full-title] Acta cardiologica
  • [ISO-abbreviation] Acta Cardiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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87. Nathan H, Raut CP, Thornton K, Herman JM, Ahuja N, Schulick RD, Choti MA, Pawlik TM: Predictors of survival after resection of retroperitoneal sarcoma: a population-based analysis and critical appraisal of the AJCC staging system. Ann Surg; 2009 Dec;250(6):970-6
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  • RESULTS: In 1365 patient undergoing resection of primary RPS, the most prevalent histologies were liposarcoma (50%), leiomyosarcoma (26%), and malignant fibrous histiocytoma (11%).


88. Check JH, Dix E, Cohen R, Check D, Wilson C: Efficacy of the progesterone receptor antagonist mifepristone for palliative therapy of patients with a variety of advanced cancer types. Anticancer Res; 2010 Feb;30(2):623-8
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  • RESULTS: Improvement in pain and energy and/or length of life was found in thymic epithelial cell carcinoma, transitional cell carcinoma of the renal pelvis, leiomyosarcoma, pancreatic carcinoma, malignant fibrous histiocytoma and another case of adenocarcinoma of the colon.
  • [MeSH-minor] Adult. Aged. Carcinoma, Transitional Cell / drug therapy. Carcinoma, Transitional Cell / secondary. Colonic Neoplasms / drug therapy. Colonic Neoplasms / pathology. Female. Histiocytoma, Malignant Fibrous / drug therapy. Histiocytoma, Malignant Fibrous / pathology. Humans. Kidney Neoplasms / drug therapy. Kidney Neoplasms / pathology. Leiomyosarcoma / drug therapy. Leiomyosarcoma / secondary. Male. Middle Aged. Pancreatic Neoplasms / drug therapy. Pancreatic Neoplasms / pathology. Survival Rate. Thymus Neoplasms / drug therapy. Thymus Neoplasms / pathology. Treatment Outcome. Young Adult

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  • (PMID = 20332480.001).
  • [ISSN] 1791-7530
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Hormone Antagonists; 0 / Receptors, Progesterone; 320T6RNW1F / Mifepristone
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89. Ando J, Sugimoto K, Tamayose K, Ando M, Kojima Y, Oshimi K: Cytokine-producing sarcoma mimics eosinophilic leukaemia. Eur J Haematol; 2007 Feb;78(2):169-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Diagnostic Errors. Granulocyte-Macrophage Colony-Stimulating Factor / secretion. Histiocytoma, Malignant Fibrous / secretion. Hypereosinophilic Syndrome / diagnosis. Interleukin-6 / secretion. Neoplasm Proteins / secretion. Paraneoplastic Syndromes / diagnosis. Sarcoma / secretion
  • [MeSH-minor] Adult. Combined Modality Therapy. Fatal Outcome. Female. Humans. Knee

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  • (PMID = 17328718.001).
  • [ISSN] 0902-4441
  • [Journal-full-title] European journal of haematology
  • [ISO-abbreviation] Eur. J. Haematol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Interleukin-6; 0 / Neoplasm Proteins; 83869-56-1 / Granulocyte-Macrophage Colony-Stimulating Factor
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90. Otsuka H, Terazawa K, Morita N, Otomi Y, Takao S, Iwamoto S, Osaki K, Harada M, Nishitani H: Thallium-201 chloride scintigraphy in soft tissue tumors. J Med Invest; 2009 Aug;56(3-4):136-41
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  • Nineteen patients were malignant and 72 were benign.
  • The retention index (RI) was calculated in 9 patients in the malignant group and in 16 patients in the benign group.
  • RESULTS: In malignant tumors, 15 of 19 patients showed high uptake in both the early and delayed phases.
  • One malignant fibrous histiocytoma patient was high only in the delayed phase and 1 liposarcoma patient was high only in the early phase.
  • RI was variable in both malignant and benign lesions and no statistically significant difference was seen between malignant and benign lesions by t-test (p=0.72).
  • CONCLUSIONS: A high (201)TlCl uptake lesion is more frequently seen in malignant tumors, but regardless of whether the tumor is benign or malignant, according to the histopathological variety, the (201)TlCl uptake pattern can not be the only indicator to differentiate malignant from benign tumors.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Diagnosis, Differential. Female. Histiocytoma, Malignant Fibrous / diagnosis. Histiocytoma, Malignant Fibrous / radionuclide imaging. Humans. Liposarcoma / diagnosis. Liposarcoma / radionuclide imaging. Magnetic Resonance Imaging. Male. Middle Aged. Radiopharmaceuticals. Young Adult

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  • (PMID = 19763026.001).
  • [ISSN] 1349-6867
  • [Journal-full-title] The journal of medical investigation : JMI
  • [ISO-abbreviation] J. Med. Invest.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0 / Thallium Radioisotopes; 7791-12-0 / thallium chloride; AD84R52XLF / Thallium
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91. Recchia F, Saggio G, Amiconi G, Di Blasio A, Cesta A, Candeloro G, Rea S, Nappi G: Cardiac metastases in malignant fibrous histiocytoma. A case report. Tumori; 2006 Jan-Feb;92(1):76-8
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  • [Title] Cardiac metastases in malignant fibrous histiocytoma. A case report.
  • Malignant fibrous histiocytoma metastasizing to the left ventricle is an uncommon form of cardiac malignancy.
  • This report describes a rare case of left ventricular metastases from a malignant fibrous histiocytoma of the posterior compartment of the right thigh, recurring five years after treatment with surgery, hyperthermic perfusion of the limb and radiotherapy.
  • [MeSH-major] Heart Neoplasms / secondary. Histiocytoma, Malignant Fibrous / secondary. Histiocytoma, Malignant Fibrous / therapy. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Heart Ventricles. Hematopoietic Stem Cell Transplantation. Humans. Male. Thigh. Treatment Outcome

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  • (PMID = 16683388.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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92. Agnihotri R, Bhat KM, Bhat GS: A rare case of malignant fibrous histiocytoma of the gingiva. J Periodontol; 2008 May;79(5):955-60
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  • [Title] A rare case of malignant fibrous histiocytoma of the gingiva.
  • BACKGROUND: Malignant fibrous histiocytoma (MFH) is an aggressive, high-grade tumor with poor prognosis.
  • [MeSH-major] Gingival Neoplasms / pathology. Histiocytoma, Malignant Fibrous / pathology
  • [MeSH-minor] Adult. Female. Humans. Maxilla. Rare Diseases. Treatment Outcome

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  • (PMID = 18454677.001).
  • [ISSN] 0022-3492
  • [Journal-full-title] Journal of periodontology
  • [ISO-abbreviation] J. Periodontol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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93. Barretina J, Taylor BS, Banerji S, Ramos AH, Lagos-Quintana M, Decarolis PL, Shah K, Socci ND, Weir BA, Ho A, Chiang DY, Reva B, Mermel CH, Getz G, Antipin Y, Beroukhim R, Major JE, Hatton C, Nicoletti R, Hanna M, Sharpe T, Fennell TJ, Cibulskis K, Onofrio RC, Saito T, Shukla N, Lau C, Nelander S, Silver SJ, Sougnez C, Viale A, Winckler W, Maki RG, Garraway LA, Lash A, Greulich H, Root DE, Sellers WR, Schwartz GK, Antonescu CR, Lander ES, Varmus HE, Ladanyi M, Sander C, Meyerson M, Singer S: Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy. Nat Genet; 2010 Aug;42(8):715-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / genetics. Liposarcoma / genetics. Sarcoma / genetics
  • [MeSH-minor] Adult. Aged. Female. Genes, Tumor Suppressor. Genome. Humans. Male. Middle Aged. Mutation


94. Ichihara K, Takahashi S, Takahashi A, Masumori N, Itoh N, Hasegawa T, Takagi Y, Taguchi K, Tsukamoto T: [Malignant fibrous histiocytoma of the retroperitoneum--review of clinical course and histopathology]. Hinyokika Kiyo; 2006 Oct;52(10):761-4
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  • [Title] [Malignant fibrous histiocytoma of the retroperitoneum--review of clinical course and histopathology].
  • The definition of malignant fibrous histiocytoma (MFH) was modified and simplified in the new WHO-Soft Tissue and Bone Tumor Classification published in 2002.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / pathology. Retroperitoneal Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Dacarbazine / administration & dosage. Doxorubicin / administration & dosage. Drug Administration Schedule. Female. Humans. Ifosfamide / administration & dosage. Male. Mesna / administration & dosage. Middle Aged

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  • (PMID = 17131862.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 7GR28W0FJI / Dacarbazine; 80168379AG / Doxorubicin; NR7O1405Q9 / Mesna; UM20QQM95Y / Ifosfamide; MAID protocol
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95. Périgny M, Dion N, Couture C, Lagacé R: [Low grade fibromyxoid sarcoma: a clinico-pathologic analysis of 7 cases]. Ann Pathol; 2006 Dec;26(6):419-25
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  • OBJECTIVES: Low-grade fibromyxoid sarcoma (LGFMS) is a malignant soft tissue tumor.
  • Histologically, the tumors were characteristically more fibrous than myxoid.
  • Cellularity was most prominent in fibrous areas and there were small, sometimes curvilinear vessels in the myxoid areas.
  • One of them demonstrated an area of dedifferentiation into a high grade pleomorphic sarcoma, malignant fibrous histiocytoma (MFH) type.
  • [MeSH-minor] Adolescent. Adult. Female. Humans. Male. Middle Aged. Neoplasm Staging

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  • (PMID = 17255901.001).
  • [ISSN] 0242-6498
  • [Journal-full-title] Annales de pathologie
  • [ISO-abbreviation] Ann Pathol
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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96. Domson GF, Shahlaee A, Reith JD, Bush CH, Gibbs CP: Infarct-associated bone sarcomas. Clin Orthop Relat Res; 2009 Jul;467(7):1820-5
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  • Sixty percent of cases arise about the knee and most are malignant fibrous histiocytomas.
  • [MeSH-major] Bone Neoplasms / complications. Histiocytoma, Malignant Fibrous / complications. Infarction / complications. Sarcoma / complications
  • [MeSH-minor] Adult. Aged. Amputation. Biopsy. Disease-Free Survival. Female. Femur / pathology. Femur / radiography. Follow-Up Studies. Humans. Limb Salvage. Magnetic Resonance Imaging. Male. Middle Aged. Necrosis. Retrospective Studies. Tibia / pathology. Tibia / radiography

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  • (PMID = 19229663.001).
  • [ISSN] 1528-1132
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2690751
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97. Zaballos P, Llambrich A, Puig S, Malvehy J: Dermoscopy is useful for the recognition of benign-malignant compound tumours. Br J Dermatol; 2005 Sep;153(3):653-6
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  • [Title] Dermoscopy is useful for the recognition of benign-malignant compound tumours.
  • In cases where a malignant neoplasm exists in association with a benign lesion it is important to make an accurate diagnosis in order to treat the lesions correctly.
  • We describe the dermoscopic characteristics of various collision or compound tumours that were composed of benign and malignant neoplasms: two cases of seborrhoeic keratosis associated with basal cell carcinoma, two cases of melanocytic naevus and basal cell carcinoma and one case of dermatofibroma associated with basal cell carcinoma.
  • [MeSH-minor] Adult. Aged. Carcinoma, Basal Cell / diagnosis. Diagnosis, Differential. Female. Histiocytoma, Benign Fibrous / diagnosis. Humans. Keratosis, Seborrheic / diagnosis. Male. Middle Aged. Nevus, Pigmented / diagnosis

  • MedlinePlus Health Information. consumer health - Skin Cancer.
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  • (PMID = 16120160.001).
  • [ISSN] 0007-0963
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 14
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98. Matsuo T, Sugita T, Shimose S, Kubo T, Ishikawa M, Yasunaga Y, Ochi M: Immunohistochemical expression of promyelocytic leukemia body in soft tissue sarcomas. J Exp Clin Cancer Res; 2008;27:73
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This study was undertaken to analyze the clinical significance of PML body expression in primary tumor samples from malignant fibrous histiocytoma (MFH) and liposarcoma patients.
  • [MeSH-major] Cell Nucleus Structures / metabolism. Histiocytoma, Malignant Fibrous / metabolism. Liposarcoma / metabolism. Nuclear Proteins / metabolism. Transcription Factors / metabolism. Tumor Suppressor Proteins / metabolism
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Immunohistochemistry. Male. Middle Aged

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  • (PMID = 19025608.001).
  • [ISSN] 1756-9966
  • [Journal-full-title] Journal of experimental & clinical cancer research : CR
  • [ISO-abbreviation] J. Exp. Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Nuclear Proteins; 0 / Transcription Factors; 0 / Tumor Suppressor Proteins; 143220-95-5 / PML protein, human
  • [Other-IDs] NLM/ PMC2611968
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99. Fu DL, Yang F, Maskay A, Long J, Jin C, Yu XJ, Xu J, Zhou ZW, Ni QX: Primary intestinal malignant fibrous histiocytoma: two case reports. World J Gastroenterol; 2007 Feb 28;13(8):1299-302
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  • [Title] Primary intestinal malignant fibrous histiocytoma: two case reports.
  • Malignant fibrous histiocytoma (MFH) occurs most commonly in the extremities and trunk, but rarely in the intestine.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / diagnosis. Intestinal Neoplasms / diagnosis
  • [MeSH-minor] Adult. Aged. Cecum / pathology. Fatal Outcome. Humans. Intestine, Small / pathology. Male

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  • (PMID = 17451221.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
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  • [Other-IDs] NLM/ PMC4147015
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100. Tanas MR, Rubin BP, Montgomery EA, Turner SL, Cook JR, Tubbs RR, Billings SD, Goldblum JR: Utility of FISH in the diagnosis of angiomatoid fibrous histiocytoma: a series of 18 cases. Mod Pathol; 2010 Jan;23(1):93-7
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  • [Title] Utility of FISH in the diagnosis of angiomatoid fibrous histiocytoma: a series of 18 cases.
  • Angiomatoid fibrous histiocytoma is a mesenchymal neoplasm of intermediate malignancy and uncertain histogenesis/line of differentiation, which occurs most commonly in the extremities of children to young adults.
  • It has a characteristic appearance characterized by a proliferation of histiocytoid cells with a lymphoid cuff and fibrous pseudocapsule, simulating the appearance of a neoplasm occurring within a lymph node.
  • Angiomatoid fibrous histiocytoma has been found to harbor three related translocations, a t(12;16)(q13;p11) resulting in a FUS/ATF1 fusion gene, t(12;22)(q13;q12) resulting in a EWSR1/ATF1 fusion, and t(2;22)(q33;q12) resulting in a EWSR1/CREB1 fusion.
  • We evaluated 18 cases of angiomatoid fibrous histiocytoma for rearrangements of EWSR1 and FUS by FISH, the largest series to date.
  • We found that 13 of 17 (76%) cases of angiomatoid fibrous histiocytoma harbored rearrangements of EWSR1; rearrangements of FUS were not detected in any of the cases.
  • This study affirms that the rearrangement of EWSR1 is a common genetic event in angiomatoid fibrous histiocytoma, and is thus useful diagnostically.
  • This study supports the fact that the rearrangement of FUS is present in only a small minority of angiomatoid fibrous histiocytomas.
  • Although it is possible that these cases contained cryptic rearrangements of EWSR1 or FUS that were not detectable by our FISH probes, it also raises the possibility that another translocation/gene fusion may be present in angiomatoid fibrous histiocytoma.
  • [MeSH-major] Biomarkers, Tumor / genetics. Calmodulin-Binding Proteins / genetics. Histiocytoma, Malignant Fibrous / genetics. In Situ Hybridization, Fluorescence. RNA-Binding Protein FUS / genetics. RNA-Binding Proteins / genetics
  • [MeSH-minor] Adolescent. Adult. Child. Female. Gene Rearrangement. Humans. Immunohistochemistry. Infant. Male. Young Adult






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