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1. Sadri D, Yazdi I: Postradiation malignant fibrous histiocytoma of the maxillary sinus. Arch Iran Med; 2007 Jul;10(3):393-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Postradiation malignant fibrous histiocytoma of the maxillary sinus.
  • Malignant fibrous histiocytoma is the most common soft tissue sarcoma in adults.
  • Recent studies have shown that the occurrence of malignant fibrous histiocytoma in the head and neck can follow radiotherapy for the treatment of other tumors.
  • We, herein, report a case of malignant fibrous histiocytoma, which developed 17 years after radiotherapy of a carcinoma in the maxillary sinus.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / diagnosis. Histiocytoma, Malignant Fibrous / etiology. Maxillary Sinus Neoplasms / diagnosis. Maxillary Sinus Neoplasms / etiology. Neoplasms, Radiation-Induced / diagnosis. Radiotherapy / adverse effects
  • [MeSH-minor] Adult. Humans. Male. Time Factors

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  • (PMID = 17604482.001).
  • [ISSN] 1029-2977
  • [Journal-full-title] Archives of Iranian medicine
  • [ISO-abbreviation] Arch Iran Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Iran
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2. Martel Villagrán J, Bueno Horcajadas A, Escribano Vera J, Jiménez Jurado D: [Radiological characteristics of malignant fibrous histiocytoma of bone]. Radiologia; 2007 May-Jun;49(3):189-93
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  • [Title] [Radiological characteristics of malignant fibrous histiocytoma of bone].
  • Malignant fibrous histiocytoma (MFH) was only recognized as a primary bone tumor a few years ago.
  • Although it is much rarer than malignant fibrous histiocytoma of soft tissues, it is not extremely uncommon.
  • [MeSH-major] Bone Neoplasms / pathology. Bone Neoplasms / radiography. Histiocytoma, Malignant Fibrous / pathology. Histiocytoma, Malignant Fibrous / radiography. Magnetic Resonance Imaging
  • [MeSH-minor] Adult. Aged. Female. Humans. Male. Middle Aged

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  • (PMID = 17524338.001).
  • [ISSN] 0033-8338
  • [Journal-full-title] Radiología
  • [ISO-abbreviation] Radiologia
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 16
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3. An JK, Oh KK: Malignant fibrous histiocytoma of chest wall. Yonsei Med J; 2005 Feb 28;46(1):177-80
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  • [Title] Malignant fibrous histiocytoma of chest wall.
  • Primary malignant fibrous histiocytoma (MFH) of the chest wall is rare.
  • [MeSH-major] Bone Neoplasms / pathology. Histiocytoma, Benign Fibrous / pathology. Ribs / pathology. Soft Tissue Neoplasms / pathology. Thoracic Wall / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans

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  • [Cites] Acta Orthop Scand. 1999 Aug;70(4):353-60 [10569265.001]
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  • (PMID = 15744825.001).
  • [ISSN] 0513-5796
  • [Journal-full-title] Yonsei medical journal
  • [ISO-abbreviation] Yonsei Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2823048
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4. Misaki H, Yamauchi T, Arai H, Yamamoto S, Sutoh H, Yoshida A, Tsutani H, Eguchi M, Nagoshi H, Naiki H, Baba H, Ueda T, Yamakawa M: Secondary malignant fibrous histiocytoma following refractory langerhans cell histiocytosis. J Clin Exp Hematop; 2009 May;49(1):33-7
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  • [Title] Secondary malignant fibrous histiocytoma following refractory langerhans cell histiocytosis.
  • We describe a rare case of secondary malignant fibrous histiocytoma (MFH) following Langerhans cell histiocytosis (LCH).
  • [MeSH-major] Histiocytoma, Malignant Fibrous / diagnosis. Histiocytosis, Langerhans-Cell / diagnosis
  • [MeSH-minor] Bone Diseases. Eosinophilic Granuloma / diagnosis. Eosinophilic Granuloma / drug therapy. Eosinophilic Granuloma / radiotherapy. Fatal Outcome. Humans. Lung Diseases. Male. Neoplasms, Second Primary / diagnosis. Neoplasms, Second Primary / etiology. Pneumonia. Salvage Therapy / methods. Young Adult

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  • (PMID = 19474515.001).
  • [ISSN] 1880-9952
  • [Journal-full-title] Journal of clinical and experimental hematopathology : JCEH
  • [ISO-abbreviation] J Clin Exp Hematop
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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5. Brahmakulam LE, Noronha BE: Malignant fibrous histiocytoma of the mandible. Ear Nose Throat J; 2010 Oct;89(10):E1-4
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  • [Title] Malignant fibrous histiocytoma of the mandible.
  • Malignant fibrous histiocytoma (MFH) of the mandible is rare.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / surgery. Mandibular Neoplasms / surgery
  • [MeSH-minor] Adult. Fatal Outcome. Female. Humans. Immunohistochemistry. Lung Neoplasms / secondary. Surgical Flaps

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  • (PMID = 20981646.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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6. Kim MS, Cho WH, Song WS, Lee SY, Jeon DG: Prognostic significance of ezrin expression in pleomorphic malignant fibrous histiocytoma. Anticancer Res; 2007 Mar-Apr;27(2):1171-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Prognostic significance of ezrin expression in pleomorphic malignant fibrous histiocytoma.
  • BACKGROUND: Newly defined pleomorphic malignant fibrous histiocytoma represents a pleomorphic sarcoma which shows no definable line of differentiation.
  • [MeSH-major] Cytoskeletal Proteins / biosynthesis. Histiocytoma, Malignant Fibrous / metabolism
  • [MeSH-minor] Adult. Aged. Female. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Staging. Prognosis. Survival Rate


7. Dias AC, Pereira Lde S, Sameshima LM, Reis FA, Vital Filho J: [Malignant fibrous histiocytoma of the eyelid: case report]. Arq Bras Oftalmol; 2009 Jan-Feb;72(1):109-12
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  • [Title] [Malignant fibrous histiocytoma of the eyelid: case report].
  • Fibrous histiocytomas represent 1% of all orbital masses and may be classified into benign, locally aggressive and malignant - these representing nearly 11% of the total.
  • In this study, the authors describe an unusual case of malignant fibrous histiocytoma of the eyelid, discussing clinical and histological features of this neoplasm.
  • [MeSH-major] Eyelid Neoplasms / pathology. Histiocytoma, Malignant Fibrous / pathology
  • [MeSH-minor] Adult. Humans. Male

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  • (PMID = 19347135.001).
  • [ISSN] 1678-2925
  • [Journal-full-title] Arquivos brasileiros de oftalmologia
  • [ISO-abbreviation] Arq Bras Oftalmol
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Brazil
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8. Guo H, Xiong Y, Nong L, Zhang S, Li T: [Reassessment of the pathological diagnosis in 33 cases of malignant fibrous histiocytoma]. Beijing Da Xue Xue Bao; 2008 Aug 18;40(4):374-9
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  • [Title] [Reassessment of the pathological diagnosis in 33 cases of malignant fibrous histiocytoma].
  • OBJECTIVE: Since malignant fibrous histiocytoma (MFH) may be taken as an undifferentiated pleomorphic sarcoma (UPS), this study was conducted to reassess 33 previously diagnosed MFH cases in the past 10 years based on the latest WHO concept.
  • RESULTS: Among the 33 cases, 17 cases (51.5%) of MFH had their diagnoses changed, including 5 leiomyosarcomas, 3 malignant peripheral nerve sheath tumors, 1 fibrosarcoma, 1 inflammatory myofibrosarcoma, 1 giant cell tumor and 1 angiomatoid fibrous histiocytoma.
  • Eleven cases (68.8%) variously expressed CD68 (KP1) and 7 cases (43.8%) expressed CD68 (PG-M1), which were much higher than leiomyosarcoma, malignant peripheral nerve sheath tumor and liposarcoma with significant difference.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Humans. Immunohistochemistry. Middle Aged

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  • (PMID = 18677383.001).
  • [ISSN] 1671-167X
  • [Journal-full-title] Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences
  • [ISO-abbreviation] Beijing Da Xue Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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9. Senel FC, Bektas D, Caylan R, Onder E, Gunhan O: Malignant fibrous histiocytoma of the mandible. Dentomaxillofac Radiol; 2006 Mar;35(2):125-8
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  • [Title] Malignant fibrous histiocytoma of the mandible.
  • We report a case of malignant fibrous histiocytoma (MFH) primary within the mandible of a 32-year-old female.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / diagnosis. Mandibular Neoplasms / diagnosis
  • [MeSH-minor] Adult. Biopsy, Fine-Needle. Female. Humans. Magnetic Resonance Imaging. Radiography, Panoramic

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  • (PMID = 16549441.001).
  • [ISSN] 0250-832X
  • [Journal-full-title] Dento maxillo facial radiology
  • [ISO-abbreviation] Dentomaxillofac Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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10. Wang CP, Chang YL, Ting LL, Yang TL, Ko JY, Lou PJ: Malignant fibrous histiocytoma of the sinonasal tract. Head Neck; 2009 Jan;31(1):85-93
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  • [Title] Malignant fibrous histiocytoma of the sinonasal tract.
  • BACKGROUND: Sinonasal malignant fibrous histiocytoma (MFH) is rare.
  • [MeSH-major] Head and Neck Neoplasms / mortality. Histiocytoma, Malignant Fibrous / mortality. Nasopharyngeal Neoplasms / radiotherapy. Neoplasms, Radiation-Induced / mortality
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Disease-Free Survival. Female. Humans. Male. Middle Aged. Prognosis. Radiotherapy Dosage. Radiotherapy, Adjuvant. Young Adult

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  • [Copyright] (c) 2008 Wiley Periodicals, Inc. Head Neck, 2009.
  • (PMID = 18853446.001).
  • [ISSN] 1097-0347
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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11. Meshikhes AW, Jan GM, Al-Jaroof AH: Fibrous histiocytoma of the breast. Saudi Med J; 2005 Feb;26(2):326-9
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  • [Title] Fibrous histiocytoma of the breast.
  • The histology after surgical excision revealed benign fibrous histiocytomas.
  • However, in patient 2 the benign fibrous histiocytoma recurred with low-grade malignancy after a year of the initial excision.
  • The second patient highlights the fact that malignant histiocytoma can occur in the pediatric age group and that the initial surgical treatment of benign fibrous histiocytoma should be aggressive to avoid recurrence and development of malignant changes.
  • We believe that our second patient is the youngest age ever reported in the literature with malignant fibrous histiocytoma.
  • [MeSH-major] Breast Neoplasms / surgery. Histiocytoma, Benign Fibrous / surgery. Neoplasm Recurrence, Local / surgery
  • [MeSH-minor] Adolescent. Adult. Female. Humans

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  • (PMID = 15770318.001).
  • [ISSN] 0379-5284
  • [Journal-full-title] Saudi medical journal
  • [ISO-abbreviation] Saudi Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Saudi Arabia
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12. Demiralp B, Erler K, Ozturan EK, Bek D, Ozdemir T, Kurt B: An uncommon presentation of malignant fibrous histiocytoma of the calcaneus. J Am Podiatr Med Assoc; 2007 May-Jun;97(3):218-22
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  • [Title] An uncommon presentation of malignant fibrous histiocytoma of the calcaneus.
  • Malignant fibrous histiocytoma of bone is the osseous counterpart of the tumor in soft tissue.
  • We describe a primary malignant fibrous histiocytoma of the calcaneal bone in a 21-year-old man.
  • [MeSH-major] Bone Neoplasms / pathology. Calcaneus. Histiocytoma, Malignant Fibrous / pathology
  • [MeSH-minor] Adult. Humans. Male

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  • (PMID = 17507531.001).
  • [ISSN] 8750-7315
  • [Journal-full-title] Journal of the American Podiatric Medical Association
  • [ISO-abbreviation] J Am Podiatr Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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13. Sakao Y, Tomimitsu S, Takeda Y, Natsuaki M, Itoh T: Malignant fibrous histiocytoma of the trachea. Jpn J Thorac Cardiovasc Surg; 2005 May;53(5):276-9
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  • [Title] Malignant fibrous histiocytoma of the trachea.
  • We experienced a rare case of malignant fibrous histiocytoma (MFH) arising in the trachea.
  • [MeSH-major] Histiocytoma, Benign Fibrous / surgery. Tracheal Neoplasms / surgery
  • [MeSH-minor] Adult. Humans. Male

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  • (PMID = 15952323.001).
  • [ISSN] 1344-4964
  • [Journal-full-title] The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai zasshi
  • [ISO-abbreviation] Jpn. J. Thorac. Cardiovasc. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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14. Garrido-Ruiz MC, Ramos P, Enguita AB, Rodriguez Peralto JL: Subcutaneous atypical fibrous histiocytoma. Am J Dermatopathol; 2009 Jul;31(5):499-501

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Subcutaneous atypical fibrous histiocytoma.
  • Benign fibrous histiocytoma is one of the most frequent benign neoplasms mainly composed of a mixture of fibroblastic and histiocytic cells, especially found in the skin (dermatofibroma), particularly in the limbs.
  • The diagnosis of cutaneous benign fibrous histiocytoma is generally easy; however, rare variants may be difficult to identify, and the diagnosis only confirmed after exhaustive histopathological examination.
  • Thus, deep subcutaneous dermatofibroma may be difficult to distinguish from dermatofibrosarcoma protuberans and dermatofibroma with monster giant cells from malignant fibrous histiocytoma and atypical fibroxanthoma.
  • We report a case of a 38-year-old woman with a painless swelling on the abdominal wall, which was totally excised and histopathologically diagnosed as subcutaneous atypical fibrous histiocytoma.
  • To the best of our knowledge, we report the first case of subcutaneous fibrous histiocytoma with monster cells.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Female. Humans. Immunohistochemistry

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  • (PMID = 19542931.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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15. Zeng Q, Tang PZ, Xu ZG, Qi YF, Wu XX, Liu WS: Primary malignant fibrous histiocytoma of the thyroid. Eur J Surg Oncol; 2009 Jun;35(6):649-53
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  • [Title] Primary malignant fibrous histiocytoma of the thyroid.
  • AIMS AND METHODS: To study the clinical features, diagnosis, and treatment of primary malignant fibrous histiocytoma of the thyroid (MFH-T).
  • [MeSH-major] Histiocytoma, Malignant Fibrous / therapy. Thyroid Neoplasms / therapy
  • [MeSH-minor] Adult. Aged. Combined Modality Therapy. Female. Humans. Male. Middle Aged. Retrospective Studies. Survival Analysis. Treatment Outcome

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  • (PMID = 18922667.001).
  • [ISSN] 1532-2157
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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16. Kim HJ, Shields CL, Eagle RC Jr, Shields JA: Fibrous histiocytoma of the conjunctiva. Am J Ophthalmol; 2006 Dec;142(6):1036-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fibrous histiocytoma of the conjunctiva.
  • PURPOSE: To review the clinical features and course of six patients with fibrous histiocytoma (FH) of the conjunctiva.
  • Surgical resection was performed in all cases, and histopathologic study demonstrated benign FH in four cases and malignant FH in two cases.
  • One patient with malignant FH showed recurrence and required repeat excision.
  • The other patient with malignant FH was treated with plaque radiotherapy to maintain control.
  • CONCLUSION: FH is a rare conjunctival tumor that can show benign or malignant features.
  • Malignant FH can demonstrate recurrence that necessitates wide resection and radiotherapy.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Histiocytoma, Benign Fibrous / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Biomarkers, Tumor / analysis. Child. Combined Modality Therapy. Female. Humans. Male. Middle Aged. Retrospective Studies

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  • (PMID = 17157587.001).
  • [ISSN] 0002-9394
  • [Journal-full-title] American journal of ophthalmology
  • [ISO-abbreviation] Am. J. Ophthalmol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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17. Chung TJ, Cheng L, Yu CY: Left ventricular malignant fibrous histiocytoma. Clin Imaging; 2007 Nov-Dec;31(6):422-4
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  • [Title] Left ventricular malignant fibrous histiocytoma.
  • Primary malignant fibrous histiocytoma (MFH) of the heart is rare.
  • [MeSH-major] Heart Neoplasms / diagnosis. Histiocytoma, Malignant Fibrous / diagnosis
  • [MeSH-minor] Adult. Contrast Media. Diagnosis, Differential. Echocardiography. Humans. Magnetic Resonance Imaging. Male

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  • (PMID = 17996607.001).
  • [ISSN] 0899-7071
  • [Journal-full-title] Clinical imaging
  • [ISO-abbreviation] Clin Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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18. Boehlke CS, Frueh BR, Flint A, Elner VM: Malignant fibrous histiocytoma of the lateral conjunctiva and anterior orbit. Ophthal Plast Reconstr Surg; 2007 Jul-Aug;23(4):338-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant fibrous histiocytoma of the lateral conjunctiva and anterior orbit.
  • Debulking biopsy was performed, which led to the diagnosis of myxoid malignant fibrous histiocytoma.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Histiocytoma, Malignant Fibrous / pathology. Orbital Neoplasms / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Female. Humans. Neoplasm Proteins / analysis. Ophthalmologic Surgical Procedures. Tomography, X-Ray Computed

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  • (PMID = 17667121.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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19. Atalar H, Başarir K, Yildiz Y, Sağlik Y: [Prognostic factors in patients with malignant fibrous histiocytoma of the extremities]. Acta Orthop Traumatol Turc; 2007 Aug-Oct;41(4):271-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Prognostic factors in patients with malignant fibrous histiocytoma of the extremities].
  • OBJECTIVES: We evaluated prognostic factors in patients with malignant fibrous histiocytoma of the extremity.
  • METHODS: The study included 26 patients (22 males, 4 females; 15 patients < age 60) with a diagnosis of malignant fibrous histiocytoma of the extremity.
  • CONCLUSION: Patients with high-grade malignant fibrous histiocytoma have a poorer prognosis.
  • [MeSH-major] Extremities. Histiocytoma, Malignant Fibrous / surgery. Neoplasm Recurrence, Local / surgery. Soft Tissue Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Combined Modality Therapy. Female. Humans. Male. Middle Aged. Neoplasm Metastasis. Survival Analysis. Turkey / epidemiology

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  • (PMID = 18180555.001).
  • [ISSN] 1017-995X
  • [Journal-full-title] Acta orthopaedica et traumatologica turcica
  • [ISO-abbreviation] Acta Orthop Traumatol Turc
  • [Language] tur
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Turkey
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20. Kubo T, Shimose S, Matsuo T, Arihiro K, Ochi M: Scalp metastasis from malignant fibrous histiocytoma of bone. J Am Acad Dermatol; 2008 Nov;59(5 Suppl):S88-91
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  • [Title] Scalp metastasis from malignant fibrous histiocytoma of bone.
  • Malignant fibrous histiocytoma (MFH) of bone is a relatively rare primary malignant neoplasm and an aggressive tumor, characterized by a high frequency of local recurrence and distant metastasis.
  • [MeSH-major] Bone Neoplasms / pathology. Head and Neck Neoplasms / secondary. Histiocytoma, Malignant Fibrous / pathology. Scalp / pathology. Skin Neoplasms / secondary
  • [MeSH-minor] Adult. Female. Humans. Tibia


21. Suri RM, Deschamps C, Cassivi SD, Nichols FC 3rd, Allen MS, Schleck CD, Pairolero PC: Pulmonary resection for metastatic malignant fibrous histiocytoma: an analysis of prognostic factors. Ann Thorac Surg; 2005 Nov;80(5):1847-52
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  • [Title] Pulmonary resection for metastatic malignant fibrous histiocytoma: an analysis of prognostic factors.
  • BACKGROUND: Factors affecting recurrence and survival after pulmonary resection for metastatic malignant fibrous histiocytoma (MFH) are not well known.
  • Malignant fibrous histiocytoma metastasis was solitary in 29 patients (28%), multiple/unilateral in 33 (32%), and multiple/bilateral in 41 (40%).
  • [MeSH-major] Histiocytoma, Malignant Fibrous / surgery. Lung Neoplasms / secondary
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Combined Modality Therapy. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / surgery. Survival Analysis

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  • (PMID = 16242467.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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22. Mandal S, Mandal AK: Malignant fibrous histiocytoma following radiation therapy and chemotherapy for Hodgkin's lymphoma. Int J Clin Oncol; 2007 Feb;12(1):52-5
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  • [Title] Malignant fibrous histiocytoma following radiation therapy and chemotherapy for Hodgkin's lymphoma.
  • Malignant fibrous histiocytoma (MFH) originates from primitive mesenchymal cells and has the capacity for dual differentiation into histiocytes and fibroblasts.
  • [MeSH-major] Bone Neoplasms / etiology. Histiocytoma, Malignant Fibrous / etiology. Hodgkin Disease / therapy. Muscle Neoplasms / etiology
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / adverse effects. Bleomycin / adverse effects. Chemotherapy, Adjuvant. Dacarbazine / adverse effects. Doxorubicin / adverse effects. Humans. Male. Mechlorethamine / adverse effects. Neoplasms, Radiation-Induced / etiology. Prednisone / adverse effects. Procarbazine / adverse effects. Radiotherapy, Adjuvant. Vinblastine / adverse effects. Vincristine / adverse effects


23. Olmedo DG, Michanié E, Oivi L, Santini-Araujo E, Cabrini RL: Malignant fibrous histiocytoma associated with coxofemoral arthrodesis. Tumori; 2007 Sep-Oct;93(5):504-7
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  • [Title] Malignant fibrous histiocytoma associated with coxofemoral arthrodesis.
  • However, few reports have discussed the potential development of malignant tumors associated with prosthetic structures in humans.
  • [MeSH-major] Arthrodesis / adverse effects. Femoral Fractures / surgery. Histiocytoma, Benign Fibrous / etiology. Metals / adverse effects. Osteosarcoma / etiology
  • [MeSH-minor] Adult. Female. Humans

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  • (PMID = 18038887.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Metals
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24. Xu WJ, Hao DP, Liu SE, Yang XD, Li SK: [Radiological diagnosis of primary malignant fibrous histiocytoma of bone]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2006 Feb;28(1):105-9
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  • [Title] [Radiological diagnosis of primary malignant fibrous histiocytoma of bone].
  • OBJECTIVE: To explore the radiological diagnosis of primary malignant fibrous histiocytoma (MFH) of bone.
  • [MeSH-major] Bone Neoplasms / diagnosis. Histiocytoma, Malignant Fibrous / diagnosis. Magnetic Resonance Imaging. Tomography, X-Ray Computed
  • [MeSH-minor] Adult. Aged. Female. Humans. Male. Middle Aged. Retrospective Studies. X-Ray Film

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  • (PMID = 16548202.001).
  • [ISSN] 1000-503X
  • [Journal-full-title] Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
  • [ISO-abbreviation] Zhongguo Yi Xue Ke Xue Yuan Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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25. Lin X, Zeng S, Yang C, Li C, Yang D: [Clinical analysis on 28 cases of head-neck malignant fibrous histiocytoma]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2009 Oct;23(19):886-8, 893
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  • [Title] [Clinical analysis on 28 cases of head-neck malignant fibrous histiocytoma].
  • OBJECTIVE: To analyze the clinical feature and treatment of head-neck malignant fibrous histiocytoma (MFH).
  • [MeSH-major] Head and Neck Neoplasms. Histiocytoma, Malignant Fibrous
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Male. Middle Aged. Retrospective Studies. Young Adult

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  • (PMID = 20120875.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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26. Ichihara K, Takahashi S, Takahashi A, Masumori N, Itoh N, Hasegawa T, Takagi Y, Taguchi K, Tsukamoto T: [Malignant fibrous histiocytoma of the retroperitoneum--review of clinical course and histopathology]. Hinyokika Kiyo; 2006 Oct;52(10):761-4
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  • [Title] [Malignant fibrous histiocytoma of the retroperitoneum--review of clinical course and histopathology].
  • The definition of malignant fibrous histiocytoma (MFH) was modified and simplified in the new WHO-Soft Tissue and Bone Tumor Classification published in 2002.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / pathology. Retroperitoneal Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Dacarbazine / administration & dosage. Doxorubicin / administration & dosage. Drug Administration Schedule. Female. Humans. Ifosfamide / administration & dosage. Male. Mesna / administration & dosage. Middle Aged

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  • (PMID = 17131862.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 7GR28W0FJI / Dacarbazine; 80168379AG / Doxorubicin; NR7O1405Q9 / Mesna; UM20QQM95Y / Ifosfamide; MAID protocol
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27. Idbaih A, Coindre JM, Derré J, Mariani O, Terrier P, Ranchère D, Mairal A, Aurias A: Myxoid malignant fibrous histiocytoma and pleomorphic liposarcoma share very similar genomic imbalances. Lab Invest; 2005 Feb;85(2):176-81
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  • [Title] Myxoid malignant fibrous histiocytoma and pleomorphic liposarcoma share very similar genomic imbalances.
  • Malignant fibrous histiocytoma (MFH) is the most common soft tissue sarcoma.
  • [MeSH-major] Chromosome Deletion. Chromosomes, Human. Histiocytoma, Benign Fibrous / genetics. Liposarcoma / genetics. Soft Tissue Neoplasms / genetics
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Chromosome Mapping. Female. Humans. In Situ Hybridization. Karyotyping. Male. Middle Aged


28. Li YR, Akbari E, Tretiakova MS, Hart J, Akbari M, Urbanski SJ, Gao ZH: Primary hepatic malignant fibrous histiocytoma: clinicopathologic characteristics and prognostic value of ezrin expression. Am J Surg Pathol; 2008 Aug;32(8):1144-58
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  • [Title] Primary hepatic malignant fibrous histiocytoma: clinicopathologic characteristics and prognostic value of ezrin expression.
  • Primary hepatic malignant fibrous histiocytoma (MFH) is a rare entity with ill-defined clinicopathologic characteristics.
  • [MeSH-major] Biomarkers, Tumor / analysis. Cytoskeletal Proteins / analysis. Histiocytoma, Malignant Fibrous / chemistry. Liver / chemistry. Liver Neoplasms / chemistry
  • [MeSH-minor] Adult. Aged. Cytogenetic Analysis. Diagnosis, Differential. Female. Gene Expression Regulation, Neoplastic. Hepatectomy. Humans. Immunohistochemistry. Male. Microscopy, Electron, Transmission. Middle Aged. Neoplasm Staging. Survival Analysis. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 18545143.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Cytoskeletal Proteins; 0 / ezrin
  • [Number-of-references] 57
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29. Rossi S, Szuhai K, Ijszenga M, Tanke HJ, Zanatta L, Sciot R, Fletcher CD, Dei Tos AP, Hogendoorn PC: EWSR1-CREB1 and EWSR1-ATF1 fusion genes in angiomatoid fibrous histiocytoma. Clin Cancer Res; 2007 Dec 15;13(24):7322-8
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  • [Title] EWSR1-CREB1 and EWSR1-ATF1 fusion genes in angiomatoid fibrous histiocytoma.
  • PURPOSE: Angiomatoid fibrous histiocytoma (AFH) is a low-grade mesenchymal neoplasm which usually occurs in children and adolescents.
  • [MeSH-major] Cyclic AMP Response Element-Binding Protein / genetics. Histiocytoma, Malignant Fibrous / genetics. Oncogene Proteins, Fusion / genetics. Soft Tissue Neoplasms / genetics. Transcription Factors / genetics
  • [MeSH-minor] Adolescent. Adult. Base Sequence. Child. Child, Preschool. Female. Humans. In Situ Hybridization, Fluorescence. Male. Reverse Transcriptase Polymerase Chain Reaction

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  • (PMID = 18094413.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CREB1 protein, human; 0 / Cyclic AMP Response Element-Binding Protein; 0 / EWS-ATF1 fusion protein, human; 0 / Oncogene Proteins, Fusion; 0 / Transcription Factors
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30. Padula GD, Schmitz M: Adult paratesticular malignant fibrous histiocytoma treated with surgery, systemic chemotherapy and postoperative adjuvant radiotherapy. J Cancer Res Ther; 2006 Oct-Dec;2(4):201-2
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  • [Title] Adult paratesticular malignant fibrous histiocytoma treated with surgery, systemic chemotherapy and postoperative adjuvant radiotherapy.
  • Paratesticular malignant fibrous histiocytoma is an extremely rare malignancy of the scrotum.
  • We present here a case of a 57-year-old man with a diagnosis of high-grade malignant fibrous histiocytoma of the left intrascrotal region who underwent radical orchiectomy, systemic chemotherapy and postoperative radiotherapy.
  • [MeSH-major] Genital Neoplasms, Male / therapy. Histiocytoma, Malignant Fibrous / therapy. Scrotum / radiation effects

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  • (PMID = 17998705.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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31. Datarkar A, Hazare VK: Malignant fibrous histiocytoma: a case report. J Maxillofac Oral Surg; 2009 Jun;8(2):196-8

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  • [Title] Malignant fibrous histiocytoma: a case report.
  • Malignant Fibrous Histiocytoma (MFH) is a controversial soft tissue malignancy whose pathogenesis continues to be redefined.
  • It remains the most often used term for soft tissue sarcomas of late adult life.
  • A case of malignant fibrous histiocytoma, which posed a diagnostic difficulty, is presented here.

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  • [Cites] Oral Surg Oral Med Oral Pathol. 1989 Oct;68(4):436-43 [2552370.001]
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  • (PMID = 23139506.001).
  • [ISSN] 0972-8279
  • [Journal-full-title] Journal of maxillofacial and oral surgery
  • [ISO-abbreviation] J Maxillofac Oral Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3453940
  • [Keywords] NOTNLM ; Malignant fibrous histiocytoma (MHF) / Mandible
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32. Xiao JY, Ye ZX, Wang SL, Wang LS: [Value of imaging in the diagnosis of primary malignant fibrous histiocytoma of bone]. Zhonghua Zhong Liu Za Zhi; 2005 Jun;27(6):364-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Value of imaging in the diagnosis of primary malignant fibrous histiocytoma of bone].
  • OBJECTIVE: To investigate the imaging feature of primary malignant fibrous histiocytoma of the bone (PBMFH) by the conventional radiography, CT and MRI, and to evaluate these different imaging methods in its diagnosis.
  • RESULTS: Though the imaging appearance of PBMFH varied in different cases, all the imaging findings of malignant bone tumors were revealed.
  • CONCLUSION: Primary malignant bone fibrous histiocytoma, a rare primary malignant bone tumor, is most frequently located in the long bone.
  • The imaging characteristics may be of value in differentiating MFH from the other malignant bone tumors.
  • [MeSH-major] Bone Neoplasms / diagnosis. Histiocytoma, Malignant Fibrous / diagnosis. Magnetic Resonance Imaging. Tomography, X-Ray Computed
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Male. Middle Aged. Retrospective Studies

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  • (PMID = 16117901.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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33. Fu DL, Yang F, Maskay A, Long J, Jin C, Yu XJ, Xu J, Zhou ZW, Ni QX: Primary intestinal malignant fibrous histiocytoma: two case reports. World J Gastroenterol; 2007 Feb 28;13(8):1299-302
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary intestinal malignant fibrous histiocytoma: two case reports.
  • Malignant fibrous histiocytoma (MFH) occurs most commonly in the extremities and trunk, but rarely in the intestine.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / diagnosis. Intestinal Neoplasms / diagnosis
  • [MeSH-minor] Adult. Aged. Cecum / pathology. Fatal Outcome. Humans. Intestine, Small / pathology. Male

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  • (PMID = 17451221.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC4147015
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34. De Cesare A, Fiori E, Burza A, Ciardi A, Bononi M, Izzo L, Volpino P, Cavallaro A, Cangemi V: Malignant fibrous histiocytoma of the breast. Report of two cases and review of the literature. Anticancer Res; 2005 Jan-Feb;25(1B):505-8
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  • [Title] Malignant fibrous histiocytoma of the breast. Report of two cases and review of the literature.
  • Among these tumors, malignant fibrous histiocytoma (MFH) is very rare.
  • [MeSH-major] Breast Neoplasms / diagnosis. Histiocytoma, Benign Fibrous / diagnosis
  • [MeSH-minor] Adult. Aged. Breast / pathology. Female. Fibroblasts / metabolism. Humans. Immunohistochemistry. Lymphatic Metastasis. Mammography. Time Factors

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  • (PMID = 15816619.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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35. Agnihotri R, Bhat KM, Bhat GS: A rare case of malignant fibrous histiocytoma of the gingiva. J Periodontol; 2008 May;79(5):955-60
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  • [Title] A rare case of malignant fibrous histiocytoma of the gingiva.
  • BACKGROUND: Malignant fibrous histiocytoma (MFH) is an aggressive, high-grade tumor with poor prognosis.
  • [MeSH-major] Gingival Neoplasms / pathology. Histiocytoma, Malignant Fibrous / pathology
  • [MeSH-minor] Adult. Female. Humans. Maxilla. Rare Diseases. Treatment Outcome

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  • (PMID = 18454677.001).
  • [ISSN] 0022-3492
  • [Journal-full-title] Journal of periodontology
  • [ISO-abbreviation] J. Periodontol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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36. Sabesan T, Xuexi W, Yongfa Q, Pingzhang T, Ilankovan V: Malignant fibrous histiocytoma: outcome of tumours in the head and neck compared with those in the trunk and extremities. Br J Oral Maxillofac Surg; 2006 Jun;44(3):209-12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant fibrous histiocytoma: outcome of tumours in the head and neck compared with those in the trunk and extremities.
  • Malignant fibrous histiocytoma is one of the commonest soft tissue sarcomas in adults, affecting, in order of frequency, the extremities, trunk and head and neck.
  • We treated 131 patients with malignant fibrous histiocytoma by radical, wide, or marginal resection.
  • [MeSH-major] Head and Neck Neoplasms / surgery. Histiocytoma, Malignant Fibrous / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / surgery. Prognosis. Retrospective Studies. Treatment Outcome

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  • (PMID = 16026908.001).
  • [ISSN] 0266-4356
  • [Journal-full-title] The British journal of oral & maxillofacial surgery
  • [ISO-abbreviation] Br J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Scotland
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37. Su HW, Hsu CS, Lin YH, Hsu MI, Chiang HK, Chou SY: Malignant fibrous histiocytoma during pregnancy: a case report. Taiwan J Obstet Gynecol; 2006 Mar;45(1):86-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant fibrous histiocytoma during pregnancy: a case report.
  • All the removed specimens were sent for pathologic examination, and the results showed a sarcoma favoring malignant fibrous histiocytoma with its primary origin in the left atrium.
  • [MeSH-major] Bone Neoplasms / secondary. Heart Neoplasms / pathology. Histiocytoma, Malignant Fibrous / secondary. Humerus. Pregnancy Complications, Neoplastic. Shoulder Joint
  • [MeSH-minor] Adult. Chemotherapy, Adjuvant. Fatal Outcome. Female. Heart Atria. Humans. Infant, Newborn. Postpartum Period. Pregnancy. Pregnancy Trimester, Third. Tomography, X-Ray Computed


38. Koplas MC, Lefkowitz RA, Bauer TW, Joyce MJ, Ilaslan H, Landa J, Sundaram M: Imaging findings, prevalence and outcome of de novo and secondary malignant fibrous histiocytoma of bone. Skeletal Radiol; 2010 Aug;39(8):791-8
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  • [Title] Imaging findings, prevalence and outcome of de novo and secondary malignant fibrous histiocytoma of bone.
  • OBJECTIVE: To evaluate the radiographic and magnetic resonance (MR) imaging features of primary and secondary malignant fibrous histiocytoma in bone and determine the demographics, prevalence and outcome of patients with this tumor.
  • MATERIALS AND METHODS: A retrospective search of files from two institutions identified 28 patients with malignant fibrous histiocytoma (MFH) of bone.
  • MR imaging showed variable and somewhat unusual low to intermediate T2 signal characteristics for a radiographically malignant osteolytic lesion.
  • [MeSH-major] Bone Neoplasms / diagnosis. Bone Neoplasms / radiography. Histiocytoma, Malignant Fibrous
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Female. Humans. Longitudinal Studies. Magnetic Resonance Imaging. Male. Middle Aged. Osteolysis / radiography. Prevalence. Retrospective Studies

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  • (PMID = 19936744.001).
  • [ISSN] 1432-2161
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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39. Miyake M, Tateishi U, Maeda T, Arai Y, Hasegawa T, Sugimura K: Diaphyseal medullary stenosis with pleomorphic malignant fibrous histiocytoma of the bone: 99mTc hydroxymethylenediphosphonate and 201Tl chloride scintigraphy findings. Ann Nucl Med; 2006 Apr;20(3):233-6
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  • [Title] Diaphyseal medullary stenosis with pleomorphic malignant fibrous histiocytoma of the bone: 99mTc hydroxymethylenediphosphonate and 201Tl chloride scintigraphy findings.
  • DMS has a high incidence of pleomorphic malignant fibrous histiocytoma (MFH).
  • [MeSH-major] Bone Neoplasms / radionuclide imaging. Camurati-Engelmann Syndrome / radionuclide imaging. Histiocytoma, Malignant Fibrous / radionuclide imaging. Technetium Tc 99m Medronate / analogs & derivatives. Thallium
  • [MeSH-minor] Adult. Humans. Male. Radiopharmaceuticals


40. Salemis NS, Gourgiotis S, Tsiambas E, Panagiotopoulos N, Karameris A, Tsohataridis E: Primary intra-abdominal malignant fibrous histiocytoma: a highly aggressive tumor. J Gastrointest Cancer; 2010 Dec;41(4):238-42
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  • [Title] Primary intra-abdominal malignant fibrous histiocytoma: a highly aggressive tumor.
  • BACKGROUND AND PURPOSE: Malignant fibrous histiocytoma (MFH) is the most common soft-tissue sarcoma of late adult life occurring predominantly in the extremities.
  • [MeSH-major] Abdomen / pathology. Histiocytoma, Malignant Fibrous / secondary. Soft Tissue Neoplasms / pathology

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  • (PMID = 20419356.001).
  • [ISSN] 1941-6636
  • [Journal-full-title] Journal of gastrointestinal cancer
  • [ISO-abbreviation] J Gastrointest Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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41. Dilek TU, Dilek S, Pata O, Tataroglu C, Tok E: Malignant fibrous histiocytoma of the ovary: a case report. Int J Gynecol Cancer; 2006 Jan-Feb;16 Suppl 1:352-6
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  • [Title] Malignant fibrous histiocytoma of the ovary: a case report.
  • Malignant fibrous histiocytoma is the most common type of soft tissue sarcoma in adults.
  • Primary malignant fibrous histiocytoma of the ovary is extremely rare, with only three previously reported cases.
  • We reported a rare and uncommon localization of malignant fibrous histiocytoma in a 22-year-old woman.
  • She was referred for adjuvant chemotherapy to our center with the diagnosis of storiform-pleomorphic malignant fibrous histiocytoma.
  • Histopathologic examination revealed inflammatory, malignant fibrous histiocytoma.
  • The management of malignant fibrous histiocytoma is controversial because of the heterogenous nature of the disease.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / surgery. Ovarian Neoplasms / surgery
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Cisplatin / therapeutic use. Cyclophosphamide / therapeutic use. Female. Humans. Reoperation

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  • (PMID = 16515621.001).
  • [ISSN] 1048-891X
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 8N3DW7272P / Cyclophosphamide; Q20Q21Q62J / Cisplatin
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42. Mizukami H, Yajima N, Wada R, Matsumoto K, Kojima M, Klöppel G, Yagihashi S: Pancreatic malignant fibrous histiocytoma, inflammatory myofibroblastic tumor, and inflammatory pseudotumor related to autoimmune pancreatitis: characterization and differential diagnosis. Virchows Arch; 2006 May;448(5):552-60
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  • [Title] Pancreatic malignant fibrous histiocytoma, inflammatory myofibroblastic tumor, and inflammatory pseudotumor related to autoimmune pancreatitis: characterization and differential diagnosis.
  • Malignant fibrous histiocytoma (MFH) and inflammatory myofibroblastic tumor (IMT) are uncommon primary non-epithelial cell tumors of the pancreas.
  • [MeSH-major] Granuloma, Plasma Cell / pathology. Histiocytoma, Malignant Fibrous / pathology. Neoplasms, Muscle Tissue / pathology. Pancreatic Neoplasms / pathology. Pancreatitis / pathology
  • [MeSH-minor] Adult. Autoimmune Diseases / complications. Base Sequence. Diagnosis, Differential. Female. Gene Expression. Gene Expression Profiling. Humans. Immunohistochemistry. Ki-67 Antigen / metabolism. Male. Middle Aged. Mutation. Pancreatectomy. Polymerase Chain Reaction. Tumor Suppressor Protein p53 / genetics. Tumor Suppressor Protein p53 / metabolism


43. Tarkkanen M, Larramendy ML, Böhling T, Serra M, Hattinger CM, Kivioja A, Elomaa I, Picci P, Knuutila S: Malignant fibrous histiocytoma of bone: analysis of genomic imbalances by comparative genomic hybridisation and C-MYC expression by immunohistochemistry. Eur J Cancer; 2006 May;42(8):1172-80
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  • [Title] Malignant fibrous histiocytoma of bone: analysis of genomic imbalances by comparative genomic hybridisation and C-MYC expression by immunohistochemistry.
  • Malignant fibrous histiocytoma (MFH) of bone is a rare, highly malignant tumour.
  • [MeSH-major] Bone Neoplasms / genetics. Genes, myc / genetics. Histiocytoma, Malignant Fibrous / genetics
  • [MeSH-minor] Adolescent. Adult. Aged. Base Sequence. Child. Chromosome Aberrations. Female. Humans. Immunohistochemistry. Male. Middle Aged. Nucleic Acid Hybridization. Osteosarcoma / genetics. Proto-Oncogene Proteins c-myc / metabolism. Soft Tissue Neoplasms / genetics

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  • (PMID = 16630715.001).
  • [ISSN] 0959-8049
  • [Journal-full-title] European journal of cancer (Oxford, England : 1990)
  • [ISO-abbreviation] Eur. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Proto-Oncogene Proteins c-myc
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44. Hoki Y, Hiraku Y, Ma N, Murata M, Matsumine A, Nagahama M, Shintani K, Uchida A, Kawanishi S: iNOS-dependent DNA damage in patients with malignant fibrous histiocytoma in relation to prognosis. Cancer Sci; 2007 Feb;98(2):163-8
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  • [Title] iNOS-dependent DNA damage in patients with malignant fibrous histiocytoma in relation to prognosis.
  • Malignant fibrous histiocytoma (MFH) is one of the most common soft tissue sarcomas.
  • [MeSH-major] DNA Damage. Histiocytoma, Malignant Fibrous / diagnosis. Histiocytoma, Malignant Fibrous / genetics. Nitric Oxide Synthase Type II / metabolism
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Cyclooxygenase 2 / metabolism. Female. Guanine / analogs & derivatives. Guanine / biosynthesis. Humans. Inflammation Mediators / metabolism. Male. Membrane Proteins / metabolism. Middle Aged. NF-kappa B / metabolism. Neoplasm Metastasis. Prognosis. Survival Rate

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  • [ErratumIn] Cancer Sci. 2007 Mar;98(3):464
  • (PMID = 17233833.001).
  • [ISSN] 1347-9032
  • [Journal-full-title] Cancer science
  • [ISO-abbreviation] Cancer Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / 8-nitroguanine; 0 / Inflammation Mediators; 0 / Membrane Proteins; 0 / NF-kappa B; 5Z93L87A1R / Guanine; EC 1.14.13.39 / Nitric Oxide Synthase Type II; EC 1.14.99.1 / Cyclooxygenase 2; EC 1.14.99.1 / PTGS2 protein, human
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45. Häfner HM, Moehrle M, Eder S, Trilling B, Röcken M, Breuninger H: 3D-Histological evaluation of surgery in dermatofibrosarcoma protuberans and malignant fibrous histiocytoma: differences in growth patterns and outcome. Eur J Surg Oncol; 2008 Jun;34(6):680-6
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  • [Title] 3D-Histological evaluation of surgery in dermatofibrosarcoma protuberans and malignant fibrous histiocytoma: differences in growth patterns and outcome.
  • AIMS: To evaluate the microscopic growth pattern of dermatofibrosarcoma protuberans (DFSP) and malignant fibrous histiocytoma (MFH) and the long-term outcome using 3D-histologic surgery with paraffin sections to cover complete margins and to detect subclinical spreads very sensitively.
  • MFH is significantly more malignant.
  • [MeSH-major] Dermatofibrosarcoma / pathology. Dermatofibrosarcoma / surgery. Histiocytoma, Malignant Fibrous / pathology. Histiocytoma, Malignant Fibrous / surgery. Imaging, Three-Dimensional. Mohs Surgery. Skin Neoplasms / pathology. Skin Neoplasms / surgery
  • [MeSH-minor] Adult. Disease-Free Survival. Female. Humans. Kaplan-Meier Estimate. Male. Middle Aged. Neoplasm Recurrence, Local. Prospective Studies. Retrospective Studies

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  • (PMID = 17716851.001).
  • [ISSN] 1532-2157
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
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46. Mesgarzadeh AH, Farahani RM, Treister N: Malignant fibrous histiocytoma of the mandible in the context of a traumatic Marjolin's ulcer. J Tissue Viability; 2008 May;17(2):38-43
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  • [Title] Malignant fibrous histiocytoma of the mandible in the context of a traumatic Marjolin's ulcer.
  • The lesion was diagnosed as a malignant fibrous histiocytoma of storiform-pleomorphic type based on the previous descriptions.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / etiology. Mandibular Injuries / complications. Mandibular Neoplasms / etiology. Skin Ulcer / complications
  • [MeSH-minor] Accidental Falls. Adult. Biopsy. Causality. Cell Transformation, Neoplastic. Chronic Disease. Fatal Outcome. Humans. Male. Mandibular Prosthesis Implantation. Neoplasm Recurrence, Local. Radiography, Panoramic. Radiotherapy, Adjuvant. Rare Diseases. Tomography, X-Ray Computed

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  • (PMID = 18343314.001).
  • [ISSN] 0965-206X
  • [Journal-full-title] Journal of tissue viability
  • [ISO-abbreviation] J Tissue Viability
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 42
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47. Spanos C, Trigonis S, Aggelidou S, Efstratiou I, Kiskinis D, Syrrakos T: Primary malignant fibrous histiocytoma of the jejunum metastatic to the spine: report of a case. Int J Gastrointest Cancer; 2005;35(2):143-5
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  • [Title] Primary malignant fibrous histiocytoma of the jejunum metastatic to the spine: report of a case.
  • We report a case of malignant fibrous histiocytoma (MFH) metastatic to the spine.
  • The lead point of the intussusception was histologically diagnosed to be a high-grade malignant fibrous histiocytoma.
  • [MeSH-major] Histiocytoma, Benign Fibrous / secondary. Intussusception / etiology. Jejunal Neoplasms / pathology. Spinal Neoplasms / secondary
  • [MeSH-minor] Adult. Humans. Male. Tomography, X-Ray Computed

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  • (PMID = 15879629.001).
  • [ISSN] 1537-3649
  • [Journal-full-title] International journal of gastrointestinal cancer
  • [ISO-abbreviation] Int J Gastrointest Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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48. Yonemoto T, Tatezaki S, Ishii T, Iwata S, Takeuchi Y, Araki A: Histological vascular invasion by tumors is a risk factor for distant metastasis in malignant fibrous histiocytoma. Anticancer Res; 2005 Mar-Apr;25(2B):1337-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Histological vascular invasion by tumors is a risk factor for distant metastasis in malignant fibrous histiocytoma.
  • Therefore, we studied the risk factors associated with distant metastasis that appear in malignant fibrous histiocytoma.
  • MATERIALS AND METHODS: The study group comprised sixty patients treated for malignant fibrous histiocytoma at our hospital between 1991 and 2002.
  • CONCLUSION: Histological vascular invasion by tumors is a risk factor associated with distant metastasis that appears in malignant fibrous histiocytoma.
  • [MeSH-major] Histiocytoma, Benign Fibrous / blood supply. Vascular Neoplasms / secondary
  • [MeSH-minor] Adolescent. Adult. Age Factors. Aged. Female. Humans. Male. Middle Aged. Multivariate Analysis. Neoplasm Invasiveness / pathology. Neoplasm Metastasis. Retrospective Studies. Risk Factors

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  • (PMID = 15865088.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
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49. Abou-Jaoude M, El Ali M: Malignant fibrous histiocytoma: a case report and literature review. Int Surg; 2009 Jul-Sep;94(3):196-200
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  • [Title] Malignant fibrous histiocytoma: a case report and literature review.
  • Malignant fibrous histiocytoma (MFH) is the most common soft tissue sarcoma in late adult life.
  • [MeSH-major] Genital Neoplasms, Male / pathology. Genital Neoplasms, Male / surgery. Histiocytoma, Malignant Fibrous / pathology. Histiocytoma, Malignant Fibrous / surgery. Spermatic Cord / pathology

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  • (PMID = 20187510.001).
  • [ISSN] 0020-8868
  • [Journal-full-title] International surgery
  • [ISO-abbreviation] Int Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 50
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50. Koletsa T, Hytiroglou P, Semoglou C, Drevelegas A, Karkavelas G: Angiomatoid fibrous histiocytoma with cystic structures of sweat duct origin. Pathol Int; 2007 Aug;57(8):513-6
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  • [Title] Angiomatoid fibrous histiocytoma with cystic structures of sweat duct origin.
  • Angiomatoid fibrous histiocytoma is an unusual soft tissue tumor, mostly arising in the subcutaneous fibro-adipose tissue of children and young adults and measuring a few centimeters in greatest dimension.
  • Reported herein is a unique case of angiomatoid fibrous histiocytoma containing epithelium-lined cystic structures.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / pathology. Neoplasms, Adnexal and Skin Appendage / pathology. Soft Tissue Neoplasms / pathology. Sweat Glands / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Cysts / chemistry. Cysts / pathology. Cysts / surgery. Female. Humans. Immunohistochemistry. Leg / pathology. Magnetic Resonance Imaging. Treatment Outcome

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  • (PMID = 17610476.001).
  • [ISSN] 1320-5463
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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51. Carvalho RM, Taleb A, Carvalho GL, Avila M: [Conjunctival fibrous histiocytoma simulating atipical pterygium in the Amazon region: case report]. Arq Bras Oftalmol; 2010 Nov-Dec;73(6):534-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Conjunctival fibrous histiocytoma simulating atipical pterygium in the Amazon region: case report].
  • An inedited case in the Brazilian literature of conjunctival fibrous histiocytoma discovered during a wide scale community project accomplished by the team of the Center of Reference in Ophthalmology of the Hospital das Clínicas da Universidade Federal de Goiás in the Amazon region is reported.
  • The histopathologic diagnosis was fibrous histiocytoma.
  • The evolution demonstrated the tumoral growth and the possibility of a malignant lesion.
  • [MeSH-major] Conjunctival Neoplasms / pathology. Histiocytoma, Benign Fibrous / pathology. Pterygium / pathology
  • [MeSH-minor] Adult. Brazil. Diagnosis, Differential. Female. Humans

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  • (PMID = 21271031.001).
  • [ISSN] 1678-2925
  • [Journal-full-title] Arquivos brasileiros de oftalmologia
  • [ISO-abbreviation] Arq Bras Oftalmol
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Brazil
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52. Hwang SS, Park SY, Park YH: The CT and F-FDG PET/CT appearance of primary renal malignant fibrous histiocytoma. J Med Imaging Radiat Oncol; 2010 Aug;54(4):365-7
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  • [Title] The CT and F-FDG PET/CT appearance of primary renal malignant fibrous histiocytoma.
  • Renal malignant fibrous histiocytoma (MFH) is a rare, primary renal tumour.
  • [MeSH-major] Fluorodeoxyglucose F18. Histiocytoma, Malignant Fibrous / diagnosis. Kidney Neoplasms / diagnosis. Positron-Emission Tomography / methods. Radiopharmaceuticals. Tomography, X-Ray Computed / methods
  • [MeSH-minor] Adult. Follow-Up Studies. Humans. Kidney / radiography. Kidney / radionuclide imaging. Kidney / surgery. Male

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  • (PMID = 20718917.001).
  • [ISSN] 1754-9485
  • [Journal-full-title] Journal of medical imaging and radiation oncology
  • [ISO-abbreviation] J Med Imaging Radiat Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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53. Choudhury M, Nangia A, Singh SK, Pujani M, Thomas S: Cytohistomorphologic features of malignant fibrous histiocytoma of the breast: a case report. Acta Cytol; 2010 Sep-Oct;54(5 Suppl):985-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytohistomorphologic features of malignant fibrous histiocytoma of the breast: a case report.
  • BACKGROUND: Malignant mesenchymal tumors constitute < 1% of all malignant neoplasms of the breast.
  • CASE: A case of recurrent primary malignant fibrous histiocytoma (MFH) occurred in the breast in a 32-year-old woman.
  • FNAC was suggestive of malignant mesenchymal tumor, most probably MFH.
  • CONCLUSION: Malignant fibrous histiocytoma of the breast is a rare entity, and a complete clinicopathologic correlation with immunohistochemical profile is essential to arrive at a correct diagnosis and guide appropriate management of the patient.
  • [MeSH-major] Breast Neoplasms / pathology. Histiocytoma, Malignant Fibrous / pathology
  • [MeSH-minor] Adult. Cell Nucleus / pathology. Diagnosis, Differential. Female. Giant Cells / pathology. Humans. Mastectomy

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  • (PMID = 21053583.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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54. Hsieh SC, Chen CY, Chan WP: Malignant fibrous histiocytoma of the heart: a case report. Acta Cardiol; 2010 Feb;65(1):85-7
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  • [Title] Malignant fibrous histiocytoma of the heart: a case report.
  • Malignant fibrous histiocytoma (MFH) in the heart is rare.
  • [MeSH-major] Heart Neoplasms / diagnosis. Histiocytoma, Malignant Fibrous / diagnosis
  • [MeSH-minor] Adult. Biopsy. Cardiac Surgical Procedures / methods. Diagnosis, Differential. Echocardiography, Transesophageal. Fatal Outcome. Female. Heart Atria. Humans. Tomography, X-Ray Computed

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  • (PMID = 20306896.001).
  • [ISSN] 0001-5385
  • [Journal-full-title] Acta cardiologica
  • [ISO-abbreviation] Acta Cardiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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55. Recchia F, Saggio G, Amiconi G, Di Blasio A, Cesta A, Candeloro G, Rea S, Nappi G: Cardiac metastases in malignant fibrous histiocytoma. A case report. Tumori; 2006 Jan-Feb;92(1):76-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiac metastases in malignant fibrous histiocytoma. A case report.
  • Malignant fibrous histiocytoma metastasizing to the left ventricle is an uncommon form of cardiac malignancy.
  • This report describes a rare case of left ventricular metastases from a malignant fibrous histiocytoma of the posterior compartment of the right thigh, recurring five years after treatment with surgery, hyperthermic perfusion of the limb and radiotherapy.
  • [MeSH-major] Heart Neoplasms / secondary. Histiocytoma, Malignant Fibrous / secondary. Histiocytoma, Malignant Fibrous / therapy. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Heart Ventricles. Hematopoietic Stem Cell Transplantation. Humans. Male. Thigh. Treatment Outcome

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  • (PMID = 16683388.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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56. Antonescu CR, Dal Cin P, Nafa K, Teot LA, Surti U, Fletcher CD, Ladanyi M: EWSR1-CREB1 is the predominant gene fusion in angiomatoid fibrous histiocytoma. Genes Chromosomes Cancer; 2007 Dec;46(12):1051-60
SciCrunch. OMIM: Data: Gene Annotation .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] EWSR1-CREB1 is the predominant gene fusion in angiomatoid fibrous histiocytoma.
  • The molecular hallmark of angiomatoid fibrous histiocytoma (AFH) is not well defined, with only six cases with specific gene fusions reported to date, consisting of either FUS-ATF1 or EWSR1-ATF1.
  • [MeSH-major] Calmodulin-Binding Proteins / genetics. Cyclic AMP Response Element-Binding Protein / genetics. Gene Fusion. Histiocytoma, Malignant Fibrous / genetics. RNA-Binding Proteins / genetics
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Cytogenetic Analysis. Female. Gene Expression. Humans. In Situ Hybridization, Fluorescence. Male. Middle Aged. Reverse Transcriptase Polymerase Chain Reaction

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  • [Copyright] (c) 2007 Wiley-Liss, Inc.
  • (PMID = 17724745.001).
  • [ISSN] 1045-2257
  • [Journal-full-title] Genes, chromosomes & cancer
  • [ISO-abbreviation] Genes Chromosomes Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CREB1 protein, human; 0 / Calmodulin-Binding Proteins; 0 / Cyclic AMP Response Element-Binding Protein; 0 / EWSR1 protein, human; 0 / RNA-Binding Proteins
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57. Enomoto K, Sakurai K, Amano S, Shiono M: [A case of malignant fibrous histiocytoma (MFH) which produced breast cancer after an operation]. Gan To Kagaku Ryoho; 2008 Nov;35(12):2225-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of malignant fibrous histiocytoma (MFH) which produced breast cancer after an operation].
  • Histopathology diagnosis revealed it to be malignant fibrous histiocytoma (MFH).
  • [MeSH-major] Breast Neoplasms / pathology. Histiocytoma, Malignant Fibrous / pathology. Neoplasm Recurrence, Local / pathology
  • [MeSH-minor] Adult. Female. Humans. Magnetic Resonance Imaging. Mastectomy. Tomography, X-Ray Computed

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  • (PMID = 19106578.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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58. Issakov J, Kollender Y, Soyfer V, Bickels J, Flusser G, Meller I, Merimsky O: A single-team experience of limb sparing approach in adults with high-grade malignant fibrous histiocytoma. Oncol Rep; 2005 Oct;14(4):1071-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A single-team experience of limb sparing approach in adults with high-grade malignant fibrous histiocytoma.
  • Malignant fibrous histiocytoma (MFH) is the most common subtype of soft-tissue sarcoma (STS).
  • During 8 years, 42 adult patients with high-grade limb MFH were approached by LSS and RT.
  • [MeSH-major] Extremities / pathology. Histiocytoma, Benign Fibrous / radiotherapy. Histiocytoma, Benign Fibrous / surgery. Soft Tissue Neoplasms / radiotherapy. Soft Tissue Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Disease-Free Survival. Female. Humans. Male. Middle Aged. Radiotherapy, Adjuvant. Recurrence. Retrospective Studies. Time Factors. Treatment Outcome

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  • (PMID = 16142374.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
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59. Shahoon H, Esmaeili M, Nematollahi M: Eight-year Follow-up of Malignant Fibrous Histiocytoma (Undifferentiated High-grade Pleomorphic Sarcoma) of the Maxilla: Case Report and Review of the Literature. J Dent Res Dent Clin Dent Prospects; 2009;3(1):32-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Eight-year Follow-up of Malignant Fibrous Histiocytoma (Undifferentiated High-grade Pleomorphic Sarcoma) of the Maxilla: Case Report and Review of the Literature.
  • Malignant fibrous histiocytoma (MFH) is the most common soft tissue sarcoma of late adult life and may also arise as a primary tumor in bone.
  • It is a rare condition that constitutes less than 1% of the malignant tumors of bone and commonly occurs in the mathaphysis of long bones of extremities such as the femur and tibia.
  • MFH of the jaws is a highly malignant tumor that recurs, metastasizes, and usually causes death despite aggressive surgical therapy.

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  • [Cites] Ear Nose Throat J. 1988 Oct;67(10):773-4, 776, 778-9 [2854516.001]
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  • (PMID = 23230479.001).
  • [ISSN] 2008-210X
  • [Journal-full-title] Journal of dental research, dental clinics, dental prospects
  • [ISO-abbreviation] J Dent Res Dent Clin Dent Prospects
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Iran
  • [Other-IDs] NLM/ PMC3517202
  • [Keywords] NOTNLM ; Oral cancer / malignant fibrous histiocytoma / maxilla / undifferentiated high grade pleomorphic sarcoma
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60. Bölke E, Ruf L, Budach W, Reinecke P, Röhrborn A, Pape H, Schwarz A, Schmitt G, Aul C: Tandem high-dose chemotherapy supported by autologous peripheral blood stem-cell transplantation and radiotherapy for recurrent malignant fibrous histiocytoma. Wien Klin Wochenschr; 2005 Dec;117(23-24):833-6
Hazardous Substances Data Bank. IFOSFAMIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tandem high-dose chemotherapy supported by autologous peripheral blood stem-cell transplantation and radiotherapy for recurrent malignant fibrous histiocytoma.
  • Malignant fibrous histiocytoma (MFH) is a soft-tissue sarcoma created from fibroblast cells and characterized by a high rate of metastasis or recurrence with poor prognosis.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Hematopoietic Stem Cell Transplantation. Histiocytoma, Malignant Fibrous / therapy. Radiotherapy. Soft Tissue Neoplasms / therapy
  • [MeSH-minor] Adult. Combined Modality Therapy. Doxorubicin / administration & dosage. Female. Humans. Ifosfamide / administration & dosage. Thoracic Surgery. Transplantation, Autologous. Treatment Outcome


61. Hoki Y, Murata M, Hiraku Y, Ma N, Matsumine A, Uchida A, Kawanishi S: 8-Nitroguanine as a potential biomarker for progression of malignant fibrous histiocytoma, a model of inflammation-related cancer. Oncol Rep; 2007 Nov;18(5):1165-9
Hazardous Substances Data Bank. GUANINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] 8-Nitroguanine as a potential biomarker for progression of malignant fibrous histiocytoma, a model of inflammation-related cancer.
  • Hypoxia-inducible factor (HIF)-1alpha has been established as a prognostic biomarker in various tumors, including malignant fibrous histiocytoma (MFH).
  • [MeSH-major] Biomarkers, Tumor / metabolism. Guanine / analogs & derivatives. Histiocytoma, Malignant Fibrous / metabolism. NF-kappa B / metabolism
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Disease Progression. Female. Humans. Hypoxia-Inducible Factor 1, alpha Subunit / metabolism. Inflammation. Inflammation Mediators. Male. Middle Aged. Prognosis. Survival Rate

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  • (PMID = 17914567.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / 8-nitroguanine; 0 / Biomarkers, Tumor; 0 / HIF1A protein, human; 0 / Hypoxia-Inducible Factor 1, alpha Subunit; 0 / Inflammation Mediators; 0 / NF-kappa B; 5Z93L87A1R / Guanine
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62. Hartel PH, Jackson J, Ducatman BS, Zhang P: CD99 immunoreactivity in atypical fibroxanthoma and pleomorphic malignant fibrous histiocytoma: a useful diagnostic marker. J Cutan Pathol; 2006 Sep;33 Suppl 2:24-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] CD99 immunoreactivity in atypical fibroxanthoma and pleomorphic malignant fibrous histiocytoma: a useful diagnostic marker.
  • Atypical fibroxanthoma (AFX), a benign lesion, and pleomorphic malignant fibrous histiocytoma (MFH) are thought to represent points along the same neoplastic spectrum but with different prognoses and treatments.
  • [MeSH-major] Antigens, CD / biosynthesis. Biomarkers, Tumor / biosynthesis. Cell Adhesion Molecules / biosynthesis. Fibroma / metabolism. Fibroma / pathology. Gene Expression Regulation, Neoplastic. Histiocytoma, Malignant Fibrous / metabolism. Histiocytoma, Malignant Fibrous / pathology. Xanthomatosis / metabolism. Xanthomatosis / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Male. Middle Aged

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  • (PMID = 16972949.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Biomarkers, Tumor; 0 / CD99 protein, human; 0 / Cell Adhesion Molecules
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63. Skoulakis CE, Papadakis CE, Datseris GE, Drivas EI, Kyrmizakis DE, Bizakis JG: Subcutaneous benign fibrous histiocytoma of the cheek. Case report and review of the literature. Acta Otorhinolaryngol Ital; 2007 Apr;27(2):90-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Subcutaneous benign fibrous histiocytoma of the cheek. Case report and review of the literature.
  • Fibrous histiocytoma is a benign tumour composed of a mixture of fibroblastic and histiocytic cells.
  • Based on the location of this tumour, fibrous histiocytoma are usually divided into cutaneous types and those involving deep tissues.
  • The diagnosis of fibrous histiocytoma may be clinically difficult when the lesion is located in the deep tissues, and is frequently confirmed after local excision.
  • The most important diagnostic distinction is the separation of this tumour from aggressive forms of fibrohistiocytic neoplasms, including dermatofibrosarcoma protuberans and malignant fibrous histiocytoma.
  • The lesion had been totally excised under local anaesthesia, and histopathology revealed a benign fibrous histiocytoma.
  • The diagnosis, location, treatment and prognosis of fibrous histiocytoma are also discussed.
  • [MeSH-major] Cheek / pathology. Histiocytoma, Benign Fibrous / pathology
  • [MeSH-minor] Adult. Humans. Male. Severity of Illness Index

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  • [Cites] J Cutan Pathol. 2000 Jan;27(1):36-9 [10660130.001]
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  • (PMID = 17608138.001).
  • [ISSN] 0392-100X
  • [Journal-full-title] Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale
  • [ISO-abbreviation] Acta Otorhinolaryngol Ital
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 18
  • [Other-IDs] NLM/ PMC2640009
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64. Khalkhali K, Azizi MR, Atighechi S: A fibrous histiocytoma of intermediate malignancy arisen from the parotid gland. Arch Iran Med; 2007 Jan;10(1):100-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A fibrous histiocytoma of intermediate malignancy arisen from the parotid gland.
  • The light microscopic and immunohistochemical characteristics of a case of fibrous histiocytoma of intermediate malignancy arising from the parotid gland are presented.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / pathology. Parotid Neoplasms / pathology
  • [MeSH-minor] Adult. Biopsy, Fine-Needle. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Oral Surgical Procedures / methods

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  • (PMID = 17198464.001).
  • [ISSN] 1029-2977
  • [Journal-full-title] Archives of Iranian medicine
  • [ISO-abbreviation] Arch Iran Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Iran
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65. Takase K, Suzuki H, Matsuoka H: The usefulness of latissimus dorsi transfer for reconstruction for malignant fibrous histiocytoma in the infraspinatus muscle region: a case report. West Indian Med J; 2010 Jan;59(1):106-9
Hazardous Substances Data Bank. GADOPENTETATE DIMEGLUMINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The usefulness of latissimus dorsi transfer for reconstruction for malignant fibrous histiocytoma in the infraspinatus muscle region: a case report.
  • Malignant fibrous histiocytoma (MFH) is a type of highly malignant soft tissue sarcoma with a predilection for the extremities of adults.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / surgery. Muscle, Skeletal / pathology. Muscle, Skeletal / surgery. Reconstructive Surgical Procedures / methods. Shoulder / surgery. Soft Tissue Neoplasms / surgery. Surgical Flaps
  • [MeSH-minor] Adult. Biopsy. Contrast Media. Female. Gadolinium DTPA. Humans. Magnetic Resonance Imaging. Tomography, X-Ray Computed

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  • (PMID = 20931927.001).
  • [ISSN] 0043-3144
  • [Journal-full-title] The West Indian medical journal
  • [ISO-abbreviation] West Indian Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Jamaica
  • [Chemical-registry-number] 0 / Contrast Media; K2I13DR72L / Gadolinium DTPA
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66. Nair V, Weinreb I, MacNeil N, Szollosi Z, Chetty R, Ghazarian D: A unique biphasic variant of cutaneous fibrous histiocytoma with a storiform pattern and intralesional pigmented melanocytes: "storiform melano-fibrous histiocytoma". Eur J Dermatol; 2008 May-Jun;18(3):332-6
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A unique biphasic variant of cutaneous fibrous histiocytoma with a storiform pattern and intralesional pigmented melanocytes: "storiform melano-fibrous histiocytoma".
  • Dermatofibromas (cutaneous fibrous histiocytomas) are common cutaneous neoplasms of mesenchymal origin.
  • There have been reports of a spectrum of melanocytic lesions associated with dermatofibromas ranging from junctional nevi to malignant melanomas, some of which may be coincidentally associated.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adult. Antigens, CD34 / metabolism. Diagnosis, Differential. Factor XIIIa / metabolism. Female. Humans. Immunohistochemistry. In Situ Hybridization, Fluorescence. S100 Proteins / metabolism. Translocation, Genetic / genetics

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  • (PMID = 18474466.001).
  • [ISSN] 1167-1122
  • [Journal-full-title] European journal of dermatology : EJD
  • [ISO-abbreviation] Eur J Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Biomarkers, Tumor; 0 / S100 Proteins; EC 2.3.2.13 / Factor XIIIa
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67. Yu H, Wang CF, Yang WT, Zhu XZ: [Angiomatoid fibrous histiocytoma: report of 5 cases with review of literature]. Zhonghua Bing Li Xue Za Zhi; 2010 Apr;39(4):245-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Angiomatoid fibrous histiocytoma: report of 5 cases with review of literature].
  • OBJECTIVE: To study the clinicopathologic features, immunophenotype and differential diagnosis of angiomatoid fibrous histiocytoma (AFH).
  • Fibrillary neuropil-type intercellular material was identified in all cases and a fibrous pseudocapsule surrounded by lymphocytes and plasma cells was demonstrated in 3 cases.
  • CONCLUSIONS: AFH is a rare tumor of intermediate malignant potential.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aneurysm / metabolism. Aneurysm / pathology. Antigens, CD / metabolism. Antigens, Differentiation, Myelomonocytic / metabolism. Chemotherapy, Adjuvant. Child. Desmin / metabolism. Diagnosis, Differential. Female. Follow-Up Studies. Histiocytoma, Malignant Fibrous / pathology. Humans. Male. Radiotherapy, Adjuvant. Vimentin / metabolism. Young Adult

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  • (PMID = 20654123.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD68 antigen, human; 0 / Desmin; 0 / Vimentin
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68. Abe T, Yamanaka K, Nakata W, Mori N, Sekii K, Yoshioka T, Itatani H: [A case of retroperitoneal malignant fibrous histiocytoma with marked response to concurrent cisplatin and radiation therapy: a case report]. Hinyokika Kiyo; 2007 Apr;53(4):241-6
Hazardous Substances Data Bank. CIS-DIAMINEDICHLOROPLATINUM .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of retroperitoneal malignant fibrous histiocytoma with marked response to concurrent cisplatin and radiation therapy: a case report].
  • Histopathological examination showed a malignant fibrous histiocytoma (MFH).
  • [MeSH-major] Cisplatin / therapeutic use. Histiocytoma, Malignant Fibrous / drug therapy. Histiocytoma, Malignant Fibrous / radiotherapy. Radiation-Sensitizing Agents / therapeutic use. Retroperitoneal Neoplasms / drug therapy. Retroperitoneal Neoplasms / radiotherapy
  • [MeSH-minor] Adult. Combined Modality Therapy. Humans. Magnetic Resonance Imaging. Male. Tomography, X-Ray Computed

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  • (PMID = 17515074.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Radiation-Sensitizing Agents; Q20Q21Q62J / Cisplatin
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69. Park SW, Kim HJ, Lee JH, Ko YH: Malignant fibrous histiocytoma of the head and neck: CT and MR imaging findings. AJNR Am J Neuroradiol; 2009 Jan;30(1):71-6
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  • [Title] Malignant fibrous histiocytoma of the head and neck: CT and MR imaging findings.
  • BACKGROUND AND PURPOSE: Malignant fibrous histiocytoma (MFH) is uncommon in the head and neck.
  • One lesion arose in the bones with background fibrous dysplasia.
  • [MeSH-major] Head and Neck Neoplasms / diagnosis. Histiocytoma, Malignant Fibrous / diagnosis. Magnetic Resonance Imaging / methods. Tomography, X-Ray Computed / methods
  • [MeSH-minor] Adult. Aged. Female. Humans. Male. Middle Aged


70. Xi RQ, Guo MF, Xie DH, Chu W, Kang SY: [Pathologic and X-ray features of primary malignant fibrous histiocytoma of bone--a report of 16 cases]. Ai Zheng; 2006 May;25(5):614-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pathologic and X-ray features of primary malignant fibrous histiocytoma of bone--a report of 16 cases].
  • BACKGROUND & OBJECTIVE: Malignant fibrous histiocytoma (MFH) is a common soft tissue tumor, which rarely occur in the skeleton.
  • RESULTS: Pathologic manifestations of the patients were malignant multinucleated giant cells, pleomorphic and bizarre form of the tumor cells, and wheel-spoke arrangement of the fibroblast-like cells.
  • [MeSH-major] Bone Neoplasms. Femoral Neoplasms. Histiocytoma, Malignant Fibrous
  • [MeSH-minor] Adult. Aged. Chemotherapy, Adjuvant. Diagnosis, Differential. Female. Femur / pathology. Femur / radiography. Femur / surgery. Follow-Up Studies. Humans. Male. Middle Aged. Osteosarcoma / pathology. Prognosis. Radiotherapy, Adjuvant. Retrospective Studies. Tibia / pathology. Tibia / radiography. Tibia / surgery. Young Adult


71. Tanas MR, Rubin BP, Montgomery EA, Turner SL, Cook JR, Tubbs RR, Billings SD, Goldblum JR: Utility of FISH in the diagnosis of angiomatoid fibrous histiocytoma: a series of 18 cases. Mod Pathol; 2010 Jan;23(1):93-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Utility of FISH in the diagnosis of angiomatoid fibrous histiocytoma: a series of 18 cases.
  • Angiomatoid fibrous histiocytoma is a mesenchymal neoplasm of intermediate malignancy and uncertain histogenesis/line of differentiation, which occurs most commonly in the extremities of children to young adults.
  • It has a characteristic appearance characterized by a proliferation of histiocytoid cells with a lymphoid cuff and fibrous pseudocapsule, simulating the appearance of a neoplasm occurring within a lymph node.
  • Angiomatoid fibrous histiocytoma has been found to harbor three related translocations, a t(12;16)(q13;p11) resulting in a FUS/ATF1 fusion gene, t(12;22)(q13;q12) resulting in a EWSR1/ATF1 fusion, and t(2;22)(q33;q12) resulting in a EWSR1/CREB1 fusion.
  • We evaluated 18 cases of angiomatoid fibrous histiocytoma for rearrangements of EWSR1 and FUS by FISH, the largest series to date.
  • We found that 13 of 17 (76%) cases of angiomatoid fibrous histiocytoma harbored rearrangements of EWSR1; rearrangements of FUS were not detected in any of the cases.
  • This study affirms that the rearrangement of EWSR1 is a common genetic event in angiomatoid fibrous histiocytoma, and is thus useful diagnostically.
  • This study supports the fact that the rearrangement of FUS is present in only a small minority of angiomatoid fibrous histiocytomas.
  • Although it is possible that these cases contained cryptic rearrangements of EWSR1 or FUS that were not detectable by our FISH probes, it also raises the possibility that another translocation/gene fusion may be present in angiomatoid fibrous histiocytoma.
  • [MeSH-major] Biomarkers, Tumor / genetics. Calmodulin-Binding Proteins / genetics. Histiocytoma, Malignant Fibrous / genetics. In Situ Hybridization, Fluorescence. RNA-Binding Protein FUS / genetics. RNA-Binding Proteins / genetics
  • [MeSH-minor] Adolescent. Adult. Child. Female. Gene Rearrangement. Humans. Immunohistochemistry. Infant. Male. Young Adult

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  • (PMID = 19801966.001).
  • [ISSN] 1530-0285
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Calmodulin-Binding Proteins; 0 / EWSR1 protein, human; 0 / RNA-Binding Protein FUS; 0 / RNA-Binding Proteins
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72. Guo J, Zhou S, Rao NP, Pez GH: Pleomorphic malignant fibrous histiocytoma/undifferentiated high-grade pleomorphic sarcoma of the scrotum in a patient presenting as fournier gangrene: a case report. Appl Immunohistochem Mol Morphol; 2010 Oct;18(5):473-8
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  • [Title] Pleomorphic malignant fibrous histiocytoma/undifferentiated high-grade pleomorphic sarcoma of the scrotum in a patient presenting as fournier gangrene: a case report.
  • Pleomorphic malignant fibrous histiocytoma (MFH), also known as undifferentiated high-grade pleomorphic sarcoma according to the latest World Health Organization classification, is a diagnosis of exclusion and extremely rare in adult scrotal/paratesticular region.


73. Ajlan AM, Sayegh K, Powell T, David H, Riha RM, Khan J, Nahal A: Angiomatoid fibrous histiocytoma: magnetic resonance imaging appearance in 2 cases. J Comput Assist Tomogr; 2010 Sep-Oct;34(5):791-4
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  • [Title] Angiomatoid fibrous histiocytoma: magnetic resonance imaging appearance in 2 cases.
  • OBJECTIVE: Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumor usually affecting the extremities of children and young adults and has a favorable prognosis.
  • CONCLUSIONS: Although the overall features of AFH can be confused with other subtypes of malignant fibrous histiocytoma, the young age at presentation, the location of the mass, the presence of intralesional blood-filled cystic spaces with fluid-fluid levels, associated features of hemosiderin deposition, and an enhancing fibrous pseudocapsule are all potential hints favoring this entity.
  • [MeSH-major] Histiocytoma, Benign Fibrous / diagnosis. Magnetic Resonance Imaging / methods. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Adult. Aged, 80 and over. Arm. Female. Humans. Retrospective Studies. Shoulder

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  • (PMID = 20861788.001).
  • [ISSN] 1532-3145
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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74. Agaimy A, Gaumann A, Schroeder J, Dietmaier W, Hartmann A, Hofstaedter F, Wünsch PH, Mentzel T: Primary and metastatic high-grade pleomorphic sarcoma/malignant fibrous histiocytoma of the gastrointestinal tract: an approach to the differential diagnosis in a series of five cases with emphasis on myofibroblastic differentiation. Virchows Arch; 2007 Nov;451(5):949-57
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  • [Title] Primary and metastatic high-grade pleomorphic sarcoma/malignant fibrous histiocytoma of the gastrointestinal tract: an approach to the differential diagnosis in a series of five cases with emphasis on myofibroblastic differentiation.
  • Primary and metastatic so-called malignant fibrous histiocytoma/undifferentiated high-grade pleomorphic sarcoma (MFH) is rare in the gastrointestinal (GI) tract with approximately 50 primary and five metastatic cases reported so far.
  • [MeSH-major] Gastrointestinal Neoplasms / diagnosis. Histiocytoma, Malignant Fibrous / pathology. Sarcoma / pathology
  • [MeSH-minor] Adult. Aged. Cell Differentiation. Diagnosis, Differential. Female. Gastrointestinal Stromal Tumors / pathology. Heart Neoplasms / pathology. Humans. Male. Middle Aged. Muscle Neoplasms / pathology. Neoplasm Metastasis / diagnosis. Neoplasm Metastasis / pathology. Receptor, Platelet-Derived Growth Factor alpha / metabolism. Stomach Neoplasms / pathology. Thigh

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  • (PMID = 17874130.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] EC 2.7.10.1 / Receptor, Platelet-Derived Growth Factor alpha
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75. Efe T, Heyse TJ, Schofer MD, Fuchs-Winkelmann S, Rexin P, Schmitt J: Malignant fibrous histiocytoma of the distal femur after an arthroscopic anterior cruciate ligament reconstruction: A case report and a review of the literature. BMC Cancer; 2010;10:264
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  • [Title] Malignant fibrous histiocytoma of the distal femur after an arthroscopic anterior cruciate ligament reconstruction: A case report and a review of the literature.
  • BACKGROUND: Malignant degeneration in association with orthopaedic implants is a known but rare complication.
  • To our knowledge, no case of osseous malignant fibrous histiocytoma after anterior cruciate ligament reconstruction is reported in the literature.
  • Biopsy determined a malignant fibrous histiocytoma.
  • CONCLUSIONS: Though secondary malignant degeneration after orthopaedic implants or prostheses is not very likely, the attending physician should take this into consideration, especially if symptoms worsen severely over a short period of time.
  • [MeSH-major] Anterior Cruciate Ligament / surgery. Arthroscopy / adverse effects. Femoral Neoplasms / etiology. Histiocytoma, Malignant Fibrous / etiology. Tendon Transfer / adverse effects
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Arthroplasty, Replacement, Knee. Biopsy. Chemotherapy, Adjuvant. Humans. Magnetic Resonance Imaging. Male. Neoadjuvant Therapy. Pain / etiology. Reoperation. Rupture. Treatment Outcome

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  • (PMID = 20529315.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 18
  • [Other-IDs] NLM/ PMC2889898
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76. Scapolan M, Perin T, Wassermann B, Canzonieri V, Colombatti A, Italia F, Spessotto P: Expression profiles in malignant fibrous histiocytomas: clues for differentiating 'spindle cell' and 'pleomorphic' subtypes. Eur J Cancer; 2008 Jan;44(2):298-309

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  • [Title] Expression profiles in malignant fibrous histiocytomas: clues for differentiating 'spindle cell' and 'pleomorphic' subtypes.
  • We analysed 21 samples of malignant fibrous histiocytoma (MFH) distinguished into the two principal morphological categories ('spindle cell' and the 'pleomorphic' subtypes).
  • [MeSH-major] Histiocytoma, Malignant Fibrous / pathology. Neoplasm Proteins / metabolism
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Cyclin-Dependent Kinase Inhibitor p27 / metabolism. Female. Humans. Immunohistochemistry. Male. Matrix Metalloproteinase 1 / metabolism. Matrix Metalloproteinase 2 / metabolism. Matrix Metalloproteinase 9 / metabolism. Middle Aged. Neoplasm Recurrence, Local / pathology

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  • (PMID = 18054831.001).
  • [ISSN] 0959-8049
  • [Journal-full-title] European journal of cancer (Oxford, England : 1990)
  • [ISO-abbreviation] Eur. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Neoplasm Proteins; 147604-94-2 / Cyclin-Dependent Kinase Inhibitor p27; EC 3.4.24.24 / Matrix Metalloproteinase 2; EC 3.4.24.35 / Matrix Metalloproteinase 9; EC 3.4.24.7 / Matrix Metalloproteinase 1
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77. Meissner M, König V, Hrgovic I, Valesky E, Kaufmann R: Human leucocyte antigen class I and class II antigen expression in malignant fibrous histiocytoma, fibrosarcoma and dermatofibrosarcoma protuberans is significantly downregulated. J Eur Acad Dermatol Venereol; 2010 Nov;24(11):1326-32
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  • [Title] Human leucocyte antigen class I and class II antigen expression in malignant fibrous histiocytoma, fibrosarcoma and dermatofibrosarcoma protuberans is significantly downregulated.
  • To date, studies analysing HLA class I and class II expression levels in malignant fibrous histiocytomas, fibrosarcomas and dermatofibrosarcoma protuberans are limited.
  • AIMS: Therefore, we investigated the in vivo expression profile of HLA class I and class II antigens in 99 malignant fibrous histiocytomas, 20 fibrosarcomas and 34 dermatofibrosarcoma protuberans from different anatomical sites.
  • RESULTS: Frequent loss or downregulation of HLA class I and class II expression in malignant fibrous tumours was observed for the different types of tumours examined.
  • DISCUSSION: The data presented suggest for the first time a high frequency of HLA class I and class II abnormalities in malignant fibrous histiocytomas, fibrosarcomas and dermatofibrosarcoma protuberans in vivo.
  • [MeSH-major] Histiocytoma, Malignant Fibrous. Histocompatibility Antigens Class I / metabolism. Histocompatibility Antigens Class II / metabolism. Skin Neoplasms
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Antigen Presentation / immunology. Child. Child, Preschool. Dermatofibrosarcoma / immunology. Dermatofibrosarcoma / metabolism. Dermatofibrosarcoma / pathology. Down-Regulation / immunology. Female. Humans. Immunohistochemistry. Male. Middle Aged. Prognosis. Tumor Escape / immunology. Young Adult

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  • [Copyright] © 2010 The Authors. Journal of the European Academy of Dermatology and Venereology © 2010 European Academy of Dermatology and Venereology.
  • (PMID = 20337820.001).
  • [ISSN] 1468-3083
  • [Journal-full-title] Journal of the European Academy of Dermatology and Venereology : JEADV
  • [ISO-abbreviation] J Eur Acad Dermatol Venereol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Histocompatibility Antigens Class I; 0 / Histocompatibility Antigens Class II
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78. Fabre-Guillevin E, Coindre JM, Somerhausen Nde S, Bonichon F, Stoeckle E, Bui NB: Retroperitoneal liposarcomas: follow-up analysis of dedifferentiation after clinicopathologic reexamination of 86 liposarcomas and malignant fibrous histiocytomas. Cancer; 2006 Jun 15;106(12):2725-33

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  • [Title] Retroperitoneal liposarcomas: follow-up analysis of dedifferentiation after clinicopathologic reexamination of 86 liposarcomas and malignant fibrous histiocytomas.
  • Malignant fibrous histiocytoma (MFH) is no longer considered a homogeneous entity, but rather as the common morphologic appearance of various subtypes of sarcomas.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / pathology. Liposarcoma / pathology. Retroperitoneal Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Cell Differentiation. Disease Progression. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Prognosis. Retrospective Studies. Survival Rate

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  • [Copyright] Copyright 2006 American Cancer Society.
  • (PMID = 16688768.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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79. Dunham C, Hussong J, Seiff M, Pfeifer J, Perry A: Primary intracerebral angiomatoid fibrous histiocytoma: report of a case with a t(12;22)(q13;q12) causing type 1 fusion of the EWS and ATF-1 genes. Am J Surg Pathol; 2008 Mar;32(3):478-84
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  • [Title] Primary intracerebral angiomatoid fibrous histiocytoma: report of a case with a t(12;22)(q13;q12) causing type 1 fusion of the EWS and ATF-1 genes.
  • Angiomatoid fibrous histiocytoma (AFH) is generally considered a soft tissue sarcoma of low malignant potential that occurs in children/young adults and most frequently affects the extremities.
  • [MeSH-major] Brain Neoplasms / genetics. Chromosomes, Human, Pair 12. Chromosomes, Human, Pair 22. DNA-Binding Proteins / genetics. Gene Fusion. Histiocytoma, Malignant Fibrous / genetics. Nuclear Proteins / genetics. RNA-Binding Protein EWS / genetics. Translocation, Genetic
  • [MeSH-minor] Activating Transcription Factor 1. Adult. Base Sequence. Humans. In Situ Hybridization, Fluorescence. Male. Reverse Transcriptase Polymerase Chain Reaction. Transcription Factors

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  • (PMID = 18300800.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / ATF1 protein, human; 0 / Activating Transcription Factor 1; 0 / DNA-Binding Proteins; 0 / Nuclear Proteins; 0 / RNA-Binding Protein EWS; 0 / Transcription Factors; 0 / regulatory factor X transcription factors
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80. Natarajan MV, Mohanlal P, Bose JC: Limb salvage surgery complimented by customised mega prostheses for malignant fibrous histiocytomas of bone. J Orthop Surg (Hong Kong); 2007 Dec;15(3):352-6
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  • [Title] Limb salvage surgery complimented by customised mega prostheses for malignant fibrous histiocytomas of bone.
  • PURPOSE: To assess functional and oncological outcomes of patients with malignant fibrous histiocytomas of bone, after limb salvage surgery complimented by a customised prosthesis.
  • METHODS: Between May 1991 and December 2002, 15 men and 5 women (mean age, 42 years) with histologically proven malignant fibrous histiocytoma of bone underwent treatment involving limb salvage surgery complimented by a customised mega prosthesis.
  • CONCLUSION: Limb salvage surgery with chemotherapy is a viable treatment option for patients with malignant fibrous histiocytoma of bone.
  • [MeSH-major] Bone Neoplasms / surgery. Histiocytoma, Malignant Fibrous / surgery. Limb Salvage. Prostheses and Implants
  • [MeSH-minor] Adolescent. Adult. Amputation. Combined Modality Therapy. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Survival Rate. Treatment Outcome

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  • (PMID = 18162685.001).
  • [ISSN] 1022-5536
  • [Journal-full-title] Journal of orthopaedic surgery (Hong Kong)
  • [ISO-abbreviation] J Orthop Surg (Hong Kong)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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81. Botrus G, Sciot R, Debiec-Rychter M: Cutaneous aneurysmal fibrous histiocytoma with a t(12;19)(p12;q13) as the sole cytogenetic anomaly. Cancer Genet Cytogenet; 2006 Jan 15;164(2):155-8
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  • [Title] Cutaneous aneurysmal fibrous histiocytoma with a t(12;19)(p12;q13) as the sole cytogenetic anomaly.
  • We report a case of a 39-year-old woman with a recurrent aneurysmal fibrous histiocytoma of the right lower leg.
  • Our case highlights the importance of distinguishing this recurrent but benign lesion from similarly appearing malignant skin tumors.
  • [MeSH-major] Chromosomes, Human, Pair 19. Chromosomes, Human, Pair 22. Histiocytoma, Benign Fibrous / genetics. Skin Neoplasms / genetics. Translocation, Genetic
  • [MeSH-minor] Adult. Cytogenetic Analysis. Female. Humans. Leg. Proto-Oncogene Proteins / genetics. Proto-Oncogene Proteins c-ets / genetics. Repressor Proteins / genetics. Transcription Factors

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  • (PMID = 16434321.001).
  • [ISSN] 0165-4608
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / ETS translocation variant 6 protein; 0 / Proto-Oncogene Proteins; 0 / Proto-Oncogene Proteins c-ets; 0 / Repressor Proteins; 0 / Transcription Factors; 0 / proto-oncogene protein bcl-3
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82. Nooij MA, Whelan J, Bramwell VH, Taminiau AT, Cannon S, Hogendoorn PC, Pringle J, Uscinska BM, Weeden S, Kirkpatrick A, Glabbeke Mv, Craft AW, European Osteosarcoma Intergroup: Doxorubicin and cisplatin chemotherapy in high-grade spindle cell sarcomas of the bone, other than osteosarcoma or malignant fibrous histiocytoma: a European Osteosarcoma Intergroup Study. Eur J Cancer; 2005 Jan;41(2):225-30
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  • [Title] Doxorubicin and cisplatin chemotherapy in high-grade spindle cell sarcomas of the bone, other than osteosarcoma or malignant fibrous histiocytoma: a European Osteosarcoma Intergroup Study.
  • There are limited data that define the role of chemotherapy in the treatment of high-grade spindle cell sarcomas of bone, other than osteosarcoma or malignant fibrous histiocytoma (MFH-B).
  • [MeSH-minor] Adolescent. Adult. Aged. Cisplatin / administration & dosage. Cisplatin / adverse effects. Combined Modality Therapy. Disease Progression. Doxorubicin / administration & dosage. Doxorubicin / adverse effects. Female. Humans. Infusions, Intravenous. Lymphatic Metastasis. Male. Middle Aged. Prospective Studies. Survival Analysis. Treatment Outcome


83. Hoshi M, Matsumoto S, Manabe J, Tanizawa T, Shigemitsu T, Izawa N, Takeuchi K, Kawaguchi N: Malignant change secondary to fibrous dysplasia. Int J Clin Oncol; 2006 Jun;11(3):229-35
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  • [Title] Malignant change secondary to fibrous dysplasia.
  • BACKGROUND: Malignant change in fibrous dysplasia (FD) is very rare.
  • METHODS: Four cases with a malignant change in FD out of 128 cases with FD were surgically treated and followed up for a median period of 61.3 months.
  • Histopathologically, two cases were osteosarcoma, one case was malignant fibrous histiocytoma (MFH), and one case was fibrosarcoma.
  • [MeSH-major] Bone Neoplasms / etiology. Bone Neoplasms / pathology. Fibrous Dysplasia of Bone / complications. Sarcoma / etiology. Sarcoma / pathology
  • [MeSH-minor] Adult. Female. Femoral Neoplasms / etiology. Femoral Neoplasms / pathology. Femoral Neoplasms / therapy. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Retrospective Studies. Ribs. Tibia. Tomography, X-Ray Computed. Treatment Outcome


84. Niimi R, Matsumine A, Iino T, Murata T, Shintani K, Nakazora S, Nakamura T, Uehara Y, Kusuzaki K, Akiyama T, Uchida A: The expression of hDlg as a biomarker of the outcome in malignant fibrous histiocytomas. Oncol Rep; 2010 Mar;23(3):631-8

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  • [Title] The expression of hDlg as a biomarker of the outcome in malignant fibrous histiocytomas.
  • We examined the expression of hDlg immunohistochemically in 46 specimens of malignant fibrous histiocytoma (MFH).
  • [MeSH-major] Adaptor Proteins, Signal Transducing / analysis. Biomarkers, Tumor / analysis. Histiocytoma, Malignant Fibrous / chemistry. Membrane Proteins / analysis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Disease-Free Survival. Female. Humans. Immunohistochemistry. Male. Middle Aged. Prognosis

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  • (PMID = 20127000.001).
  • [ISSN] 1791-2431
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Adaptor Proteins, Signal Transducing; 0 / Biomarkers, Tumor; 0 / DLG1 protein, human; 0 / Membrane Proteins
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85. Brinck U, Cordon-Cardo C, Stachura J, Bortkiewicz P, Fischer G, Korabiowska M: Proposal of a new grading system for malignant fibrous histiocytomas. Anticancer Res; 2005 Nov-Dec;25(6B):4293-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Proposal of a new grading system for malignant fibrous histiocytomas.
  • The proposed grading system for malignant fibrous histiocytomas (MFH) comprises 3 grades of malignancy.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Female. Humans. Male. Middle Aged. Predictive Value of Tests. Prognosis

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  • (PMID = 16309231.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
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86. Matsuo T, Shimose S, Kubo T, Fujimori J, Yasunaga Y, Ochi M: Alternative lengthening of telomeres as a prognostic factor in malignant fibrous histiocytomas of bone. Anticancer Res; 2010 Dec;30(12):4959-62
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  • [Title] Alternative lengthening of telomeres as a prognostic factor in malignant fibrous histiocytomas of bone.
  • BACKGROUND: Malignant fibrous histiocytoma (MFH) of bone is a rare primary malignant neoplasm.
  • [MeSH-major] Bone Neoplasms / genetics. Histiocytoma, Malignant Fibrous / genetics. Telomere / genetics
  • [MeSH-minor] Adult. Aged. Female. Humans. Male. Middle Aged. Prognosis. RNA, Messenger / biosynthesis. RNA, Messenger / genetics. Telomerase / biosynthesis. Telomerase / genetics. Telomerase / metabolism. Young Adult

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  • (PMID = 21187476.001).
  • [ISSN] 1791-7530
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / RNA, Messenger; EC 2.7.7.49 / TERT protein, human; EC 2.7.7.49 / Telomerase
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87. Miettinen M, Fetsch JF: Reticulohistiocytoma (solitary epithelioid histiocytoma): a clinicopathologic and immunohistochemical study of 44 cases. Am J Surg Pathol; 2006 Apr;30(4):521-8
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  • [Title] Reticulohistiocytoma (solitary epithelioid histiocytoma): a clinicopathologic and immunohistochemical study of 44 cases.
  • In this study, we analyzed a uniform group of 44 lesions composed of epithelioid histiocytes, comprising a subset of lesions originally designated as reticulohistiocytoma, and propose designating them as "solitary epithelioid histiocytoma" (SEH), in line with the recently published classification proposal for histiocytic disorders.
  • It needs to be distinguished from Rosai-Dorfman disease, juvenile xanthogranuloma, a variety of granulomatous conditions, and some malignant neoplasms, including histiocytic sarcoma, melanoma, and epithelioid sarcoma.
  • [MeSH-major] Epithelioid Cells / pathology. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Age Distribution. Aged. Biomarkers, Tumor / metabolism. Child. Child, Preschool. Diagnosis, Differential. Female. Histiocytoma, Malignant Fibrous / diagnosis. Histiocytosis, Sinus / diagnosis. Humans. Male. Middle Aged. Sarcoma / diagnosis. Sex Distribution. Xanthogranuloma, Juvenile / diagnosis

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  • (PMID = 16625100.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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88. Pinedo-Onofre JA, Robles-Pérez E, Peña-Mirabal ES, Hernández-Carrillo JA, Téllez-Becerra JL: Giant solitary fibrous tumor of the pleura. Cir Cir; 2010 Jan-Feb;78(1):31-43

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  • [Title] Giant solitary fibrous tumor of the pleura.
  • BACKGROUND: Solitary fibrous tumor is the second primary malignancy of the pleura and can reach up to 39 cm in diameter; however, to be referred to as 'giant' it must occupy at least 40% of the affected hemithorax.
  • METHODS: We performed a descriptive, observational, longitudinal, and retrospective study from 2002 to 2006 on patients who underwent surgery with a diagnosis of giant solitary fibrous tumor of the pleura.
  • [MeSH-major] Pleural Neoplasms / surgery. Solitary Fibrous Tumors / surgery
  • [MeSH-minor] Adult. Aged. Angiography. Combined Modality Therapy. Dyspnea / etiology. Embolization, Therapeutic. Female. Follow-Up Studies. Histiocytoma, Malignant Fibrous / epidemiology. Histiocytoma, Malignant Fibrous / pathology. Humans. Intraoperative Complications / epidemiology. Male. Middle Aged. Neoadjuvant Therapy. Retrospective Studies. Tomography, X-Ray Computed

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  • (PMID = 20226126.001).
  • [ISSN] 0009-7411
  • [Journal-full-title] Cirugía y cirujanos
  • [ISO-abbreviation] Cir Cir
  • [Language] eng; spa
  • [Publication-type] Journal Article
  • [Publication-country] Mexico
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89. Fung KY, Law SW: Management of malignant atlanto-axial tumours. J Orthop Surg (Hong Kong); 2005 Dec;13(3):232-9

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  • [Title] Management of malignant atlanto-axial tumours.
  • PURPOSE: To review the management and outcomes of patients with malignant tumours of the atlanto-axial spine treated over a 4-year period at a tertiary hospital.
  • The atlanto-axial spine was the first presentation of malignant disease in the remaining 5 patients, whose subsequent diagnoses were multiple myeloma (n=1), carcinoma of the thyroid (n=1), malignant fibrous histiocytoma (n=2), and adenocarcinoma of unknown origin (n=1).
  • [MeSH-minor] Adult. Aged. Female. Humans. Male. Middle Aged. Retrospective Studies. Treatment Outcome

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  • (PMID = 16365485.001).
  • [ISSN] 1022-5536
  • [Journal-full-title] Journal of orthopaedic surgery (Hong Kong)
  • [ISO-abbreviation] J Orthop Surg (Hong Kong)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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90. Demiralp B, Ozdemir MT, Erler K, Basbozkurt M: Type 1 neurofibromatosis and adult extremity sarcoma. A report of two cases. Acta Orthop Belg; 2007 Jun;73(3):403-7
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  • [Title] Type 1 neurofibromatosis and adult extremity sarcoma. A report of two cases.
  • We report two cases of malignant soft-tissue tumours--one myxoid malignant fibrous histiocytoma and one pleomorphic rhabdomyosarcoma--which were diagnosed in two young adult patients with type 1 neurofibromatosis (NF 1).
  • Diagnoses of myxoid malignant fibrous histiocytoma and pleomorphic rhabdomyosarcoma in adult NF 1 patients are exceedingly rare.
  • Thus detection of subtypes of rhabdomyosarcoma and malignant fibrous histiocytoma with immunohistochemistry may be helpful for the management of these tumours among other pleomorphic sarcomas that may occur in type 1 Neurofibromatosis.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / complications. Neoplasms, Multiple Primary. Neurofibromatosis 1 / complications. Rhabdomyosarcoma / complications. Soft Tissue Neoplasms
  • [MeSH-minor] Adult. Humans. Male

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  • (PMID = 17715736.001).
  • [ISSN] 0001-6462
  • [Journal-full-title] Acta orthopaedica Belgica
  • [ISO-abbreviation] Acta Orthop Belg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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91. Zaballos P, Llambrich A, Puig S, Malvehy J: Dermoscopy is useful for the recognition of benign-malignant compound tumours. Br J Dermatol; 2005 Sep;153(3):653-6
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  • [Title] Dermoscopy is useful for the recognition of benign-malignant compound tumours.
  • In cases where a malignant neoplasm exists in association with a benign lesion it is important to make an accurate diagnosis in order to treat the lesions correctly.
  • We describe the dermoscopic characteristics of various collision or compound tumours that were composed of benign and malignant neoplasms: two cases of seborrhoeic keratosis associated with basal cell carcinoma, two cases of melanocytic naevus and basal cell carcinoma and one case of dermatofibroma associated with basal cell carcinoma.
  • [MeSH-minor] Adult. Aged. Carcinoma, Basal Cell / diagnosis. Diagnosis, Differential. Female. Histiocytoma, Benign Fibrous / diagnosis. Humans. Keratosis, Seborrheic / diagnosis. Male. Middle Aged. Nevus, Pigmented / diagnosis

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  • (PMID = 16120160.001).
  • [ISSN] 0007-0963
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 14
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92. Asavamongkolkul A, Waikakul S, Phimolsarnti R, Kiatisevi P, Wangsaturaka P: Endoprosthetic reconstruction for malignant bone and soft-tissue tumors. J Med Assoc Thai; 2007 Apr;90(4):706-17
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  • [Title] Endoprosthetic reconstruction for malignant bone and soft-tissue tumors.
  • BACKGROUND: Nowadays, the results of the management of malignant bone and soft-tissue tumors have been dramatically improved because of the advance in imaging, chemotherapy, radiation therapy, and surgical techniques.
  • Several techniques of reconstruction have been advocated and gained more popularity following malignant tumor resection by using allograft, tumor prostheses, composite allograft prosthesis, or arthrodesis.
  • OBJECTIVE: To report the preliminary results of 32 endoprosthetic reconstructions following malignant bone and soft-tissue tumor resection.
  • From March 1994 to July 2006, 32 endoprosthetic reconstructions were performed on 30 patients following malignant bone or soft-tissue tumor removal.
  • The diagnosis was conventional osteosarcoma in 16 patients, parosteal osteosarcoma in two patients, chondrosarcoma in two patients, leiomyosarcoma in two patients, failed allograft in two patients and one patient each of periosteal osteosarcoma, Ewing's sarcoma, Gorham's disease, synovial sarcoma, malignant fibrous histiocytoma, metastatic renal cell carcinoma, and prosthetic loosening.
  • CONCLUSION: Endoprosthetic reconstruction could yield satisfactory results as a wide excision and limb-salvage for patients with malignant bone and soft-tissue tumors.
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Female. Humans. Male. Middle Aged. Prostheses and Implants. Prosthesis Implantation / methods

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  • (PMID = 17487125.001).
  • [ISSN] 0125-2208
  • [Journal-full-title] Journal of the Medical Association of Thailand = Chotmaihet thangphaet
  • [ISO-abbreviation] J Med Assoc Thai
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Thailand
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93. Koga K, Nabeshima K, Nishimura N, Shishime M, Nakayama J, Iwasaki H: Microvessel density and HIF-1alpha expression correlate with malignant potential in fibrohistiocytic tumors. Eur J Dermatol; 2005 Nov-Dec;15(6):465-9
MedlinePlus Health Information. consumer health - Skin Cancer.

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  • [Title] Microvessel density and HIF-1alpha expression correlate with malignant potential in fibrohistiocytic tumors.
  • However, involvement of HIF-1alpha has never been studied in so-called fibrohistiocytic tumors, such as dermatofibroma (DF), dermatofibrosarcoma protuberans (DFSP) and malignant fibrous histiocytoma (MFH).
  • Thus, higher levels of angiogenesis and HIF-1alpha expression are both closely associated with the malignant potential in so-called fibrohistiocytic tumors, and HIF-1alpha is possibly involved in angiogenesis in MFH.
  • [MeSH-major] Hypoxia-Inducible Factor 1, alpha Subunit / biosynthesis. Neoplasms, Fibrous Tissue / metabolism. Neoplasms, Fibrous Tissue / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Female. Humans. Male. Microcirculation. Middle Aged

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  • (PMID = 16280300.001).
  • [ISSN] 1167-1122
  • [Journal-full-title] European journal of dermatology : EJD
  • [ISO-abbreviation] Eur J Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / HIF1A protein, human; 0 / Hypoxia-Inducible Factor 1, alpha Subunit
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94. Zhang R, Sun J, Wei X, Zhang H, Liu Y, Shi M, Shi Y: Reconstruction of defects with the posterior femoral fasciocutaneous flap after resection of malignant tumours of the femoral greater trochanter, sacrococcygeal region and knee. J Plast Reconstr Aesthet Surg; 2009 Feb;62(2):221-9
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  • [Title] Reconstruction of defects with the posterior femoral fasciocutaneous flap after resection of malignant tumours of the femoral greater trochanter, sacrococcygeal region and knee.
  • All underwent resection of malignant tumours, five malignant fibrous histiocytomas (MFH), two synovial sarcomas, one skin squamous cell cancer, one malignant hamartoma and one fibrosarcoma.
  • [MeSH-minor] Adult. Aged. Bone Transplantation / methods. Female. Histiocytoma, Benign Fibrous / surgery. Humans. Knee / surgery. Male. Middle Aged. Sacrococcygeal Region / surgery. Sarcoma, Synovial / surgery

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  • (PMID = 18054531.001).
  • [ISSN] 1878-0539
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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95. Ebeid W, Amin S, Abdelmegid A: Limb salvage management of pathologic fractures of primary malignant bone tumors. Cancer Control; 2005 Jan-Feb;12(1):57-61
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  • [Title] Limb salvage management of pathologic fractures of primary malignant bone tumors.
  • Diagnoses included osteosarcoma (17 patients), Ewing's sarcoma (10), malignant fibrous histiocytoma (3), and lymphoma (1).
  • [MeSH-minor] Adolescent. Adult. Child. Female. Follow-Up Studies. Humans. Lung Neoplasms / secondary. Lung Neoplasms / surgery. Male. Middle Aged. Recurrence. Treatment Outcome

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  • (PMID = 15668653.001).
  • [ISSN] 1073-2748
  • [Journal-full-title] Cancer control : journal of the Moffitt Cancer Center
  • [ISO-abbreviation] Cancer Control
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
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96. Wang J, Yin J, Zou C, Xie X, Huang G, Li H, Shen J, Han S: [Surgical treatment of proximal femoral malignant tumors]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2010 Jul;24(7):881-4
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  • [Title] [Surgical treatment of proximal femoral malignant tumors].
  • OBJECTIVE: To evaluate the clinical outcomes of the wide resection and the functional reconstruction for treating malignant tumors of the proximal femur.
  • METHODS: The clinical data were analysed from 62 patients with malignant tumors of the proximal femur treated between January 1987 and December 2007.
  • In 41 patients with primary malignant tumors having a disease course of 0.5-14.0 months, there were 16 cases of osteosarcoma, 7 cases of fibrosarcoma, 6 cases of chondrosarcoma, 6 cases of malignant fibrous histiocytoma, 4 cases of mesenchymal sarcoma,1 case of Ewing sarcoma, and 1 case of angiosarcoma, including 3 cases of type IB, 2 cases of type IIA, 35 cases of type IIB, and 1 case of type III according to Enneking stage.
  • In 21 patients with metastatic tumors, 16 had a malignant tumor history; the disease course was 0.1-28.0 months (3.4 months on average).
  • The local recurrence rate of primary malignant tumors was 4.88% (2/41).
  • CONCLUSION: When the wide resection is performed for malignant tumors of the proximal femur, better local control could be achieved.
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Male. Middle Aged. Retrospective Studies. Treatment Outcome. Young Adult

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  • (PMID = 20695391.001).
  • [ISSN] 1002-1892
  • [Journal-full-title] Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
  • [ISO-abbreviation] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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97. Wang J, Chen A, Luo Y: [Surgical management of limb salvage for osteogenic malignant tumors around knees]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2006 Oct;20(10):975-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Surgical management of limb salvage for osteogenic malignant tumors around knees].
  • OBJECTIVE: To probe a satisfactory surgical management of the limb salvage for osteogenic malignant tumors around the knees.
  • METHODS: From January 1989 to December 2001, 42 patients (19 males and 18 females, aged 12-46) with osteogenic malignant tumors around the knees underwent surgical management of the limb salvage, including prosthesis replacement, allogenous bone grafting, and bone cement with adriamycin filled.
  • Based on the pathological examination, osteosarcoma was found in 11 patients, synoviosarcoma in 4 patients, malignant fibrous histiocytoma in 3 patients, and giant cell tumor of the bone in 19 patients.
  • By the Enneking evaluating system, the patients were assessed on their reconstructed limb functions after the reconstructive operation for the musculoskeletal malignant tumors.
  • CONCLUSION: Making an early diagnosis, recognizing the operative indication, choosing the operative method, and performing the preoperative and postoperative chemotherapy and/or radiotherapy are the keys to achieving an ideal limb-salvage surgery for osteogenic malignant tumors around the knees.
  • [MeSH-minor] Adolescent. Adult. Child. Female. Follow-Up Studies. Giant Cell Tumor of Bone / surgery. Humans. Male. Middle Aged. Prosthesis Implantation. Reconstructive Surgical Procedures. Soft Tissue Neoplasms / surgery

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  • (PMID = 17140066.001).
  • [ISSN] 1002-1892
  • [Journal-full-title] Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
  • [ISO-abbreviation] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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98. King R, Googe PB, Page RN, Mihm MC Jr: Melanocytic lesions associated with dermatofibromas: a spectrum of lesions ranging from junctional nevus to malignant melanoma in situ. Mod Pathol; 2005 Aug;18(8):1043-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Melanocytic lesions associated with dermatofibromas: a spectrum of lesions ranging from junctional nevus to malignant melanoma in situ.
  • Histologically, the melanocytic lesions included junctional, compound, and dermal nevi, and malignant melanoma in situ.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Melanocytes / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adult. Antigens, Neoplasm. Factor XIIIa / analysis. Female. Humans. Immunohistochemistry. MART-1 Antigen. Male. Melanoma / metabolism. Melanoma / pathology. Middle Aged. Neoplasm Proteins / analysis. Nevus / metabolism. Nevus / pathology. Proto-Oncogene Proteins c-kit / analysis. S100 Proteins / analysis

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  • (PMID = 15803191.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / MART-1 Antigen; 0 / MLANA protein, human; 0 / Neoplasm Proteins; 0 / S100 Proteins; EC 2.3.2.13 / Factor XIIIa; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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99. Moradi B, Zahlten-Hinguranage A, Lehner B, Zeifang F: The impact of pathological fractures on therapy outcome in patients with primary malignant bone tumours. Int Orthop; 2010 Oct;34(7):1017-23
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  • [Title] The impact of pathological fractures on therapy outcome in patients with primary malignant bone tumours.
  • The primary objective of this study was to investigate the implications of pathological fractures on therapy outcome in patients with primary malignant bone tumours and to determine whether limb salvage can be safely performed.
  • A retrospective analysis of 447 patients with primary malignant bone tumours, treated between 1985 and 2005, was performed.
  • In 52 of the 447 patients, the primary malignant bone tumour was complicated by a pathological fracture.
  • These fractures were more common in malignant fibrous histiocytoma (MFH) of the bone and in the tumour stages IIa/b and III.
  • Pathological fracture in patients with primary malignant bone tumours is a predictor of worse survival and significantly increases mortality risk.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Combined Modality Therapy. Female. Germany / epidemiology. Humans. Male. Middle Aged. Neoplasm Staging. Remission Induction. Retrospective Studies. Survival Rate. Young Adult

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  • (PMID = 20012861.001).
  • [ISSN] 1432-5195
  • [Journal-full-title] International orthopaedics
  • [ISO-abbreviation] Int Orthop
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC2989037
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100. Park JH, Kang CH, Kim CH, Chae IJ, Park JH: Highly malignant soft tissue sarcoma of the extremity with a delayed diagnosis. World J Surg Oncol; 2010;8:84
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  • [Title] Highly malignant soft tissue sarcoma of the extremity with a delayed diagnosis.
  • PURPOSE: To evaluate the characteristics of highly malignant soft tissue sarcoma of the extremity with a delayed diagnosis.
  • MATERIALS AND METHODS: The clinical and radiological characteristics of 18 cases of highly malignant soft tissue sarcomas of the extremity with a delayed diagnosis were determined.
  • Seven cases of synovial sarcoma, three cases each of alveolar soft part sarcoma and malignant fibrous histiocytoma, two cases each of highly malignant leiomyosarcoma and myxofibrosarcoma, and one case of clear cell sarcoma were enrolled.
  • CONCLUSIONS: Contrary to general expectations, some soft tissue tumors that grow slowly are painless, and those that occur in superficial limbs may be highly malignant.
  • Thus, even when a slow growing, painless superficial mass is encountered in a limb, physicians should keep the possibility of highly malignant soft tissue sarcoma in mind.
  • [MeSH-minor] Adolescent. Adult. Aged. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Male. Middle Aged. Prognosis. Retrospective Studies. Time Factors. Young Adult

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  • (PMID = 20863406.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2955565
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