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1. Barbagallo GM, Caltabiano R, Parisi G, Albanese V, Lanzafame S: Giant cell ependymoma of the cervical spinal cord: case report and review of the literature. Eur Spine J; 2009 Jul;18 Suppl 2:186-90
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  • [Title] Giant cell ependymoma of the cervical spinal cord: case report and review of the literature.
  • Giant cell ependymoma (GCE) is a rare subtype, with few cases reported, mostly in the brain.
  • We describe the case of a cervical spinal cord ependymoma with pleomorphic giant cells and focal calcifications occurring in a 25-year-old woman.
  • Intraoperative analysis of frozen section tissue fragments suggested a malignant tumour; however, an obvious cleavage plane was present around most of the mass, and a macroscopically complete tumour removal could be achieved.
  • This case, the second giant-cell ependymoma to be described in the spinal cord and the first with focal calcifications, highlights the features of GCE and the discrepancy between the worrisome histological appearance, the surgical findings and the clinical relatively good prognosis.
  • [MeSH-major] Cervical Vertebrae. Ependymoma / pathology. Spinal Cord Neoplasms / pathology
  • [MeSH-minor] Adult. Female. Humans. Magnetic Resonance Imaging

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  • [Cites] Clin Neuropathol. 2001 Jan-Feb;20(1):31-7 [11220693.001]
  • [Cites] Pathol Int. 2003 Aug;53(8):539-46 [12895233.001]
  • [Cites] J Neurosurg. 2004 Jan;100(1 Suppl Spine):75-9 [14748579.001]
  • [Cites] Cancer. 1979 Nov;44(5):1839-52 [498051.001]
  • [Cites] J Neurosurg. 1988 Jun;68(6):880-3 [3286833.001]
  • [Cites] J Neurosurg. 1990 Mar;72(3):408-17 [2303876.001]
  • [Cites] Am J Surg Pathol. 1990 Aug;14(8):729-36 [2378394.001]
  • [Cites] Ultrastruct Pathol. 1994 Jan-Apr;18(1-2):43-6 [8191646.001]
  • [Cites] Am J Surg Pathol. 1996 Sep;20(9):1091-101 [8764746.001]
  • [Cites] Acta Neuropathol. 1997 Mar;93(3):310-6 [9083565.001]
  • [Cites] Am J Surg Pathol. 1998 Mar;22(3):338-46 [9500776.001]
  • [Cites] Mod Pathol. 1998 Apr;11(4):398-403 [9578093.001]
  • [Cites] Neuropathol Appl Neurobiol. 1998 Dec;24(6):434-40 [9888153.001]
  • [Cites] Neurosurgery. 1999 Apr;44(4):721-31 [10201296.001]
  • [Cites] Pathol Res Pract. 2004;200(10):717-25 [15648610.001]
  • [Cites] Brain Pathol. 2005 Oct;15(4):367-8, 373 [16389948.001]
  • [Cites] J Neurosurg. 2006 Dec;105(6):908-11 [17405264.001]
  • [Cites] Clin Neurol Neurosurg. 2008 Feb;110(2):176-81 [18006220.001]
  • [Cites] J Neurooncol. 2001 Aug;54(1):77-85 [11763426.001]
  • (PMID = 18820954.001).
  • [ISSN] 1432-0932
  • [Journal-full-title] European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
  • [ISO-abbreviation] Eur Spine J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 20
  • [Other-IDs] NLM/ PMC2899556
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2. Merchant TE, Li C, Xiong X, Kun LE, Boop FA, Sanford RA: Conformal radiotherapy after surgery for paediatric ependymoma: a prospective study. Lancet Oncol; 2009 Mar;10(3):258-66
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  • [Title] Conformal radiotherapy after surgery for paediatric ependymoma: a prospective study.
  • BACKGROUND: Therapy for ependymoma includes aggressive surgical intervention and radiotherapy administered by use of methods that keep the risk of side-effects to a minimum.
  • METHODS: Between July 11, 1997, and Nov 18, 2007, 153 paediatric patients (median age 2.9 years [range 0.9-22.9 months]) with localised ependymoma were treated.
  • 85 patients had anaplastic ependymoma; the tumours of 122 were located in the infratentorial region, and 35 had received previous chemotherapy.
  • The incidence of secondary malignant brain tumour at 7 years was 2.3% (0-5.6) and brainstem necrosis 1.6% (0-4.0).
  • Overall survival was affected by tumour grade (anaplastic vs differentiated: HR 3.98 [95% CI 1.51-10.48]; p=0.0052), extent of resection (gross total vs near total or subtotal: 0.16 [0.07-0.37]; p<0.0001), and ethnic origin (non-white vs white: 3.0 [1.21-7.44]; p=0.018).
  • EFS was affected by tumour grade (anaplastic vs differentiated: 2.52 [1.2705.01]; p=0.008), extent of resection (gross total vs near total or subtotal: 0.20 [0.11-0.39]; p<0.0001]), and sex (male vs female: 2.19 [1.03-4.66]; p=0.042).
  • Distant recurrence was only affected by tumour grade (anaplastic vs differentiated: 4.1 [1.2-14.0]; p=0.017).
  • INTERPRETATION: Treatment of ependymoma should include surgery with the aim of gross-total resection and conformal, high-dose, postoperative irradiation.
  • [MeSH-major] Brain Neoplasms / therapy. Ependymoma / therapy. Radiotherapy, Conformal / methods
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Combined Modality Therapy. Female. Humans. Infant. Male. Prospective Studies. Treatment Failure

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  • [Cites] Acta Oncol. 2000;39(1):97-100 [10752661.001]
  • [Cites] J Clin Oncol. 2001 Mar 1;19(5):1288-96 [11230470.001]
  • [Cites] J Neurooncol. 2002 Jan;56(1):87-94 [11949831.001]
  • [Cites] J Neurosurg. 2002 Oct;97(4):827-35 [12405370.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2004 Apr 1;58(5):1336-45 [15050308.001]
  • [Cites] J Clin Oncol. 2004 Aug 1;22(15):3156-62 [15284268.001]
  • [Cites] J Neurooncol. 2004 Jul;68(3):255-61 [15332330.001]
  • [Cites] Cancer Chemother Rep. 1966 Mar;50(3):163-70 [5910392.001]
  • [Cites] Br J Cancer. 1976 Dec;34(6):585-612 [795448.001]
  • [Cites] Br J Cancer. 1977 Jan;35(1):1-39 [831755.001]
  • [Cites] Neurosurgery. 1995 Oct;37(4):655-66; discussion 666-7 [8559293.001]
  • [Cites] Med Pediatr Oncol. 1996 Jul;27(1):8-14 [8614396.001]
  • [Cites] Med Pediatr Oncol. 1997 Aug;29(2):79-85 [9180907.001]
  • [Cites] J Neurosurg. 1998 Apr;88(4):695-703 [9525716.001]
  • [Cites] Med Pediatr Oncol. 1998 Jun;30(6):319-29; discussion 329-31 [9589080.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2005 Feb 1;61(2):387-91 [15667957.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2005 Dec 1;63(5):1546-54 [16115736.001]
  • [Cites] J Clin Oncol. 2006 Nov 20;24(33):5283-90 [17114662.001]
  • [Cites] Pediatr Blood Cancer. 2007 Jul;49(1):34-40 [16874765.001]
  • [Cites] Cancer. 2007 Jul 15;110(2):432-41 [17559078.001]
  • [Cites] Lancet Oncol. 2007 Aug;8(8):696-705 [17644039.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2008 May 1;71(1):87-97 [18406885.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2008 Jul 15;71(4):987-93 [18258381.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2008 Jul 15;71(4):979-86 [18325681.001]
  • [Cites] J Clin Oncol. 2008 Aug 20;26(24):3965-70 [18711186.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2008 Nov 1;72(3):892-9 [18395355.001]
  • [CommentIn] Lancet Oncol. 2009 Mar;10(3):206-7 [19261252.001]
  • (PMID = 19274783.001).
  • [ISSN] 1474-5488
  • [Journal-full-title] The Lancet. Oncology
  • [ISO-abbreviation] Lancet Oncol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA021765
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Other-IDs] NLM/ NIHMS429992; NLM/ PMC3615425
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3. Lindsey JC, Lusher ME, Strathdee G, Brown R, Gilbertson RJ, Bailey S, Ellison DW, Clifford SC: Epigenetic inactivation of MCJ (DNAJD1) in malignant paediatric brain tumours. Int J Cancer; 2006 Jan 15;118(2):346-52
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  • [Title] Epigenetic inactivation of MCJ (DNAJD1) in malignant paediatric brain tumours.
  • We examined the status of MCJ in intracranial primitive neuroectodermal tumours [PNETs, comprising cerebellar PNETs (medulloblastomas) and supratentorial PNETs (stPNETs)] and ependymomas, together representing the most common malignant brain tumours of childhood.
  • [MeSH-major] Brain Neoplasms / genetics. Ependymoma / genetics. Epigenesis, Genetic. HSP40 Heat-Shock Proteins / biosynthesis. Membrane Proteins / biosynthesis. Neuroectodermal Tumors, Primitive / genetics
  • [MeSH-minor] Adolescent. Adult. Biomarkers, Tumor. Child. Child, Preschool. DNA Methylation. Female. Gene Expression Profiling. Gene Silencing. Humans. Male. Reverse Transcriptase Polymerase Chain Reaction

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  • [Copyright] Copyright 2005 Wiley-Liss, Inc.
  • (PMID = 16049974.001).
  • [ISSN] 0020-7136
  • [Journal-full-title] International journal of cancer
  • [ISO-abbreviation] Int. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNAJC1 protein, human; 0 / HSP40 Heat-Shock Proteins; 0 / Membrane Proteins
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4. Miyazawa T, Hirose T, Nakanishi K, Uozumi Y, Tsuzuki N, Shima K: Supratentorial ectopic cortical ependymoma occurring with intratumoral hemorrhage. Brain Tumor Pathol; 2007;24(1):35-40
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  • [Title] Supratentorial ectopic cortical ependymoma occurring with intratumoral hemorrhage.
  • We report here a rare case of supratentorial ectopic cortical ependymoma.
  • A cortical ependymoma should be considered in the differential diagnosis of supratentorial cortical tumors with intraparenchymal hemorrhage and high vascularity, even if not in contact with the ventricular system.
  • Although malignant transformation is unusual in cortical ependymoma, close observation and adjunctive radiotherapy are strongly recommended after the excision.
  • [MeSH-major] Ependymoma / pathology. Glioblastoma / pathology. Neoplasm Recurrence, Local / pathology. Neoplasms, Second Primary / pathology. Supratentorial Neoplasms / pathology
  • [MeSH-minor] Adult. Hemorrhage / etiology. Humans. Magnetic Resonance Imaging. Male. Tomography, X-Ray Computed

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  • (PMID = 18095143.001).
  • [ISSN] 1433-7398
  • [Journal-full-title] Brain tumor pathology
  • [ISO-abbreviation] Brain Tumor Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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5. Vajtai I, Kuhlen D, Kappeler A, Mariani L, Zimmermann A, Paulus W: Rapid spontaneous malignant progression of supratentorial tanycytic ependymoma with sarcomatous features - "Ependymosarcoma". Pathol Res Pract; 2010 Jul 15;206(7):493-8
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  • [Title] Rapid spontaneous malignant progression of supratentorial tanycytic ependymoma with sarcomatous features - "Ependymosarcoma".
  • By analogy to gliosarcoma, the term "ependymosarcoma" has recently been coined to thematize the rare phenomenon of a malignant mesenchymal component arising within an ependymoma.
  • We report on an example of this paradigm, involving tanycytic ependymoma as the host tumor in a 40-year-old female who underwent two tumor extirpation procedures at one-year interval.
  • A histological diagnosis of tanycytic ependymoma (WHO grade II) was rendered, and no adjuvant therapy given.
  • Histology showed a biphasic glial-sarcomatous architecture with remnants of the original ependymoma now displaying hypercellularity and atypical - yet not frankly anaplastic - features.
  • To the best of our knowledge, this is the first documentation of tanycytic ependymoma undergoing malignant transformation, one driven by a highly anaplastic mesenchymal component, corresponding to "ependymosarcoma".
  • [MeSH-major] Cell Transformation, Neoplastic / pathology. Ependymoma / pathology. Gliosarcoma / pathology. Neoplasm Recurrence, Local / pathology. Supratentorial Neoplasms / pathology
  • [MeSH-minor] Adult. Disease Progression. Female. Humans. Immunophenotyping. Magnetic Resonance Imaging

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  • [Copyright] Copyright 2009 Elsevier GmbH. All rights reserved.
  • (PMID = 19853384.001).
  • [ISSN] 1618-0631
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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6. Mahfouz S, Aziz AA, Gabal SM, el-Sheikh S: Immunohistochemical study of CD99 and EMA expression in ependymomas. Medscape J Med; 2008;10(2):41
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  • Tumors of the central nervous system (CNS) represent a unique, heterogeneous population of neoplasms and include both benign and malignant tumors.
  • It was found that all 38 ependymoma cases (classic and nonclassic) showed positive membranous and intracytoplasmic CD99 immunoreactivity.
  • In regard to EMA immunoreactivity, which was restricted to the ependymoma group, 2 patterns of staining could be detected--the intracytoplasmic dotlike pattern and the ringlike pattern--but some cases were completely negative.
  • Thus, EMA was found to be of little value in the diagnosis of ependymoma and in the differentiation between different types and grades.
  • [MeSH-major] Antigens, CD / analysis. Biomarkers, Tumor / analysis. Brain Neoplasms / diagnosis. Brain Neoplasms / metabolism. Cell Adhesion Molecules / analysis. Ependymoma / diagnosis. Ependymoma / metabolism. Mucin-1 / analysis
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Female. Gene Expression Profiling. Humans. Infant. Infant, Newborn. Male. Middle Aged. Neoplasm Proteins / analysis. Sensitivity and Specificity

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  • [Cites] Appl Immunohistochem Mol Morphol. 2000 Mar;8(1):25-31 [10937045.001]
  • [Cites] Appl Immunohistochem Mol Morphol. 2001 Jun;9(2):125-9 [11396629.001]
  • [Cites] Diagn Cytopathol. 2002 Apr;26(4):247-50 [11933271.001]
  • [Cites] J Neurooncol. 2002 May;58(1):13-9 [12160136.001]
  • [Cites] Exp Mol Med. 2002 Jul 31;34(3):177-83 [12216109.001]
  • [Cites] Acta Neuropathol. 2003 Oct;106(4):385-8 [12898159.001]
  • [Cites] Mod Pathol. 2003 Oct;16(10):980-91 [14559980.001]
  • [Cites] Am J Pathol. 2003 Nov;163(5):1721-7 [14578171.001]
  • [Cites] Curr Treat Options Oncol. 2003 Dec;4(6):517-23 [14585232.001]
  • [Cites] Cancer. 2004 Mar 15;100(6):1230-7 [15022291.001]
  • [Cites] J Neuropathol Exp Neurol. 2004 Mar;63(3):185-92 [15055442.001]
  • [Cites] Neuropathol Appl Neurobiol. 1988 May-Jun;14(3):197-205 [3405393.001]
  • [Cites] Cancer Res. 1988 Nov 1;48(21):6127-31 [2844401.001]
  • [Cites] Acta Neuropathol. 1989;78(3):325-8 [2763805.001]
  • [Cites] Virchows Arch A Pathol Anat Histopathol. 1990;417(2):97-103 [1695040.001]
  • [Cites] Arch Pathol Lab Med. 1990 Sep;114(9):956-60 [2390011.001]
  • [Cites] Cancer. 1991 Apr 1;67(7):1886-93 [1848471.001]
  • [Cites] Acta Neuropathol. 1991;82(3):208-16 [1718129.001]
  • [Cites] Am J Surg Pathol. 1994 May;18(5):486-94 [7513503.001]
  • [Cites] J Neurooncol. 2005 Jan;71(2):189-93 [15690137.001]
  • [Cites] Brain Tumor Pathol. 2004;21(1):17-21 [15696964.001]
  • [Cites] Cancer. 2005 Jun 15;103(12):2598-605 [15861411.001]
  • [Cites] Histopathology. 2007 Feb;50(3):365-70 [17257132.001]
  • [Cites] J Neurooncol. 2002 Jul;58(3):255-70 [12187959.001]
  • [Cites] Acta Neuropathol. 1997 Mar;93(3):310-6 [9083565.001]
  • [Cites] Neuropathology. 2004 Dec;24(4):330-5 [15641594.001]
  • [Cites] Pathol Res Pract. 2004;200(10):717-25 [15648610.001]
  • (PMID = 18382710.001).
  • [ISSN] 1934-1997
  • [Journal-full-title] Medscape journal of medicine
  • [ISO-abbreviation] Medscape J Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Biomarkers, Tumor; 0 / CD99 protein, human; 0 / Cell Adhesion Molecules; 0 / Mucin-1; 0 / Neoplasm Proteins
  • [Other-IDs] NLM/ PMC2270873
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7. Oshiro S, Tsugu H, Komatsu F, Ohnishi H, Ueno Y, Sakamoto S, Fukushima T, Soma G: Evaluation of intratumoral administration of tumor necrosis factor-alpha in patients with malignant glioma. Anticancer Res; 2006 Nov-Dec;26(6A):4027-32
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  • [Title] Evaluation of intratumoral administration of tumor necrosis factor-alpha in patients with malignant glioma.
  • BACKGROUND: This study assessed safety and efficacy for intratumoral administration of tumor necrosis factor-a (TNF-SAM2) into the post-operative tumor cavity through an Ommaya reservoir for patients with malignant glioma.
  • MATERIALS AND METHODS: Seven patients with malignant glioma, comprising 3 cases with glioblastoma multiforme (GBM), 3 cases with anaplastic astrocytoma (AA) and 1 case with malignant ependymoma (ME) were included in the study.
  • CONCLUSION: Local immunotherapy with TNF-SAM2 may safely contribute to therapeutic efficacy in some patients with malignant glioma.
  • [MeSH-minor] Adult. Aged. Female. Humans. Injections, Intralesional. Male. Middle Aged. Treatment Outcome

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  • (PMID = 17195453.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Case Reports; Clinical Trial; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / TNF-SAM2; 0 / Tumor Necrosis Factor-alpha
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8. Merchant TE, Pollack IF, Loeffler JS: Brain tumors across the age spectrum: biology, therapy, and late effects. Semin Radiat Oncol; 2010 Jan;20(1):58-66
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  • In this review of glioma, ependymoma, and medulloblastoma, we highlight the differences between adults and children, including the higher incidence of spinal cord ependymoma and supratentorial high-grade glioma in the adult and a higher incidence of medulloblastoma in the child.
  • An effort is underway to better characterize adult and pediatric brain tumors biologically with an emphasis on improving our understanding of tumor genesis, malignant transformation, and some of the similarities and differences between tumor types and their response to conventional therapy.
  • [MeSH-minor] Adolescent. Adult. Age Distribution. Child. Child, Preschool. Combined Modality Therapy / methods. Disease Progression. Ependymoma / epidemiology. Ependymoma / therapy. Humans. Incidence. Infant. Infant, Newborn. Medulloblastoma / epidemiology. Medulloblastoma / therapy. Radiation Injuries. Young Adult

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  • [Cites] Lancet Oncol. 2009 Mar;10(3):258-66 [19274783.001]
  • [Cites] Brain Pathol. 2009 Jan;19(1):81-90 [18452568.001]
  • [Cites] J Pathol. 2009 Jun;218(2):172-81 [19373855.001]
  • [Cites] Neurosurgery. 2000 Sep;47(3):623-31; discussion 631-2 [10981749.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2000 Jan 15;46(2):287-95 [10661334.001]
  • [Cites] J Neurooncol. 2009 Jul;93(3):343-8 [19142584.001]
  • [Cites] Histopathology. 2000 Nov;37(5):437-44 [11119125.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2002 May 1;53(1):52-7 [12007941.001]
  • [Cites] J Pathol. 2002 Jun;197(2):238-44 [12015749.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2002 Nov 1;54(3):855-60 [12377339.001]
  • [Cites] Neurosurgery. 2003 Sep;53(3):544-53; discussion 554-5 [12943571.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2003 Nov 1;57(3):755-61 [14529781.001]
  • [Cites] N Engl J Med. 1993 Jun 17;328(24):1725-31 [8388548.001]
  • [Cites] N Engl J Med. 2005 Mar 10;352(10):978-86 [15758008.001]
  • [Cites] J Neurosurg. 2005 Apr;102(4):629-36 [15871504.001]
  • [Cites] J Clin Oncol. 2005 Dec 1;23(34):8853-62 [16314645.001]
  • [Cites] J Neurooncol. 2006 Feb;76(3):313-9 [16200343.001]
  • [Cites] Clin Cancer Res. 2006 Apr 1;12(7 Pt 1):2070-9 [16609018.001]
  • [Cites] J Clin Oncol. 2006 Sep 1;24(25):4202-8 [16943538.001]
  • [Cites] J Clin Oncol. 2007 Feb 20;25(6):682-9 [17308273.001]
  • [Cites] Brain Pathol. 2007 Apr;17(2):146-50 [17388945.001]
  • [Cites] J Clin Oncol. 2007 Apr 1;25(10):1196-208 [17401009.001]
  • [Cites] Brain. 2007 May;130(Pt 5):1338-49 [17449478.001]
  • [Cites] Neurochirurgie. 2007 Jun;53(2-3 Pt 1):66-75 [17475290.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2008 Mar 1;70(3):782-7 [17892918.001]
  • [Cites] J Clin Oncol. 2009 Aug 1;27(22):3691-7 [19581535.001]
  • [Cites] J Clin Oncol. 2009 Aug 1;27(22):3598-604 [19581536.001]
  • [Cites] J Neurooncol. 2009 Sep;94(3):391-8 [19330288.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2010 Feb 1;76(2):496-503 [19464817.001]
  • [Cites] Childs Nerv Syst. 2009 Oct;25(10):1261-8 [19373477.001]
  • [Cites] Cancer. 2008 Apr 1;112(7):1568-74 [18278809.001]
  • [Cites] J Clin Invest. 2008 May;118(5):1739-49 [18398503.001]
  • [Cites] Arch Pathol Lab Med. 2008 Jun;132(6):993-1007 [18517285.001]
  • [Cites] J Clin Oncol. 2008 Aug 20;26(24):3965-70 [18711186.001]
  • [Cites] Curr Opin Neurol. 2008 Dec;21(6):754-61 [18989122.001]
  • [Cites] J Clin Oncol. 2009 Apr 1;27(10):1627-36 [19255330.001]
  • (PMID = 19959032.001).
  • [ISSN] 1532-9461
  • [Journal-full-title] Seminars in radiation oncology
  • [ISO-abbreviation] Semin Radiat Oncol
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA021765
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 40
  • [Other-IDs] NLM/ NIHMS425593; NLM/ PMC3529408
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9. Kurimoto M, Nagai S, Hamada H, Tsuboi Y, Hayashi N, Kubota T, Endo S: Malignant transformation of supratentorial clear cell ependymoma. Neuropathology; 2009 Jun;29(3):299-302
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant transformation of supratentorial clear cell ependymoma.
  • Recurrence of clear cell ependymoma is not a rare condition, but malignant transformation of clear cell ependymoma has not yet been well presented.
  • At this time, the tumor had an ultrastructural appearance compatible with ependymoma.
  • Thereafter, the recurrent tumors showed anaplastic features such as nuclear pleomorphisms and necrosis with pseudopallisading.
  • [MeSH-major] Brain Neoplasms / pathology. Ependymoma / pathology. Neoplasm Recurrence, Local / pathology
  • [MeSH-minor] Adult. Brain / pathology. Brain / ultrastructure. Diagnosis, Differential. Fatal Outcome. Humans. Magnetic Resonance Imaging. Male. Tomography, X-Ray Computed

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  • (PMID = 18647267.001).
  • [ISSN] 1440-1789
  • [Journal-full-title] Neuropathology : official journal of the Japanese Society of Neuropathology
  • [ISO-abbreviation] Neuropathology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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10. Azarpira N, Rakei M, Mokhtari M: Cytologic findings in malignant ependymoma: a case report. Acta Cytol; 2010 Sep-Oct;54(5 Suppl):1023-6
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  • [Title] Cytologic findings in malignant ependymoma: a case report.
  • Anaplastic ependymoma is a rare tumor that causes diagnostic difficulties in imprint cytology because of variable cytomorphologic findings.
  • [MeSH-major] Central Nervous System Neoplasms / pathology. Ependymoma / pathology
  • [MeSH-minor] Cell Aggregation. Fatal Outcome. Female. Glial Fibrillary Acidic Protein / metabolism. Humans. Rosette Formation. Tomography, X-Ray Computed. Young Adult

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  • (PMID = 21053591.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein
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11. Mogler C, Kohlhof P, Penzel R, Grenacher L, Haag GM, Schirmacher P, Mueller W: A primary malignant ependymoma of the abdominal cavity: a case report and review of the literature. Virchows Arch; 2009 Apr;454(4):475-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A primary malignant ependymoma of the abdominal cavity: a case report and review of the literature.
  • Here, we describe the first case of an overt malignant primary extraneural ependymoma in a young female patient.
  • [MeSH-major] Abdominal Cavity / pathology. Diagnostic Errors. Ependymoma / diagnosis
  • [MeSH-minor] Adult. Antineoplastic Agents / therapeutic use. Autonomic Pathways / pathology. Combined Modality Therapy. Digestive System Surgical Procedures. Female. Gastrointestinal Neoplasms / pathology. Glial Fibrillary Acidic Protein / biosynthesis. Humans. Immunohistochemistry. Peripheral Nervous System Neoplasms / pathology

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  • [Cites] Cancer. 1979 Jul;44(1):326-33 [378364.001]
  • [Cites] Neurosurg Focus. 2003 Nov 15;15(5):E13 [15323470.001]
  • [Cites] Semin Diagn Pathol. 2005 Feb;22(1):3-32 [16512597.001]
  • [Cites] Neurol India. 1969 Apr-Jun;17(2):82-4 [5823288.001]
  • [Cites] Brain Pathol. 2003 Jul;13(3):421-3 [12946033.001]
  • [Cites] Am J Surg Pathol. 1993 Aug;17(8):764-78 [8393302.001]
  • [Cites] Am J Surg Pathol. 1982 Jun;6(4):283-92 [7114357.001]
  • [Cites] Am J Surg Pathol. 1993 Jun;17(6):623-32 [8333561.001]
  • [Cites] Pathol Oncol Res. 1999;5(1):56-60 [10079380.001]
  • [Cites] J Neurosurg. 1979 Sep;51(3):383-91 [469584.001]
  • [Cites] Am J Surg Pathol. 2008 May;32(5):710-8 [18360284.001]
  • [Cites] J Neurooncol. 1992 Oct;14(2):135-42 [1432036.001]
  • [Cites] Medscape J Med. 2008 Feb 19;10 (2):41 [18382710.001]
  • [Cites] Diagn Cytopathol. 1986 Jan-Mar;2(1):62-8 [3522133.001]
  • [Cites] Pathology. 2001 Feb;33(1):26-9 [11280604.001]
  • (PMID = 19238432.001).
  • [ISSN] 1432-2307
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Glial Fibrillary Acidic Protein
  • [Number-of-references] 15
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12. Yan X, Cheng X, Liu J, Luo D, He X, Chen F, Qin C, Wang Y: Clinicopathological evaluation of immunohistochemical Ki-67 and endothelial nitric oxide synthase expression in intracranial ependymoma. Clin Invest Med; 2008;31(4):E206-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinicopathological evaluation of immunohistochemical Ki-67 and endothelial nitric oxide synthase expression in intracranial ependymoma.
  • Positive cell rates were 2.65+/-0.83 % in the low-grade, 9.63+/-0.08 % in the mid-grade, and 28.41+/-0.71 % in the high-grade ependymoma groups.
  • In the mid-grade ependymoma group eNOS was expressed moderately in 10 cases and intensely in 15.
  • CONCLUSION: Ki-67 and eNOS expression in intracranial ependymoma tissue was associated with the histopathological grade and malignant degree.
  • [MeSH-major] Brain Neoplasms. Ependymoma. Gene Expression Regulation / drug effects. Ki-67 Antigen / therapeutic use. Nitric Oxide Synthase Type III / therapeutic use
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Immunohistochemistry. Male. Middle Aged. Time Factors. Treatment Outcome

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  • (PMID = 18682044.001).
  • [ISSN] 1488-2353
  • [Journal-full-title] Clinical and investigative medicine. Médecine clinique et experimentale
  • [ISO-abbreviation] Clin Invest Med
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Canada
  • [Chemical-registry-number] 0 / Ki-67 Antigen; EC 1.14.13.39 / Nitric Oxide Synthase Type III
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13. Arai T, Tani S, Isoshima A, Nagashima H, Joki T, Takahashi-Fujigasaki J, Abe T: [Intraoperative photodynamic diagnosis for spinal ependymoma using 5-aminolevulinic acid: technical note]. No Shinkei Geka; 2006 Aug;34(8):811-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Intraoperative photodynamic diagnosis for spinal ependymoma using 5-aminolevulinic acid: technical note].
  • OBJECTIVE: The fluorescence-guided resection using 5-aminolevulinic acid (5-ALA) is a well established method for the treatment of brain tumor, especially malignant glioma.
  • In the present study, we evaluated the usefulness of PDD for spinal ependymoma using 5-ALA.
  • METHODS: Three patients with spinal ependymoma received oral doses of 5-ALA (20 mg/kg body weight) 2 hours before anesthesia induction.
  • CONCLUSION: The results of this study indicate the usefulness of 5-ALA-induced tumor fluorescence in guiding resection of spinal ependymoma.
  • [MeSH-major] Aminolevulinic Acid. Ependymoma / diagnosis. Photosensitizing Agents. Spinal Cord Neoplasms / diagnosis
  • [MeSH-minor] Adult. Female. Fluorescence. Humans. Intraoperative Period. Lighting. Magnetic Resonance Imaging. Male. Middle Aged. Porphyrins. Sensitivity and Specificity

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  • (PMID = 16910494.001).
  • [ISSN] 0301-2603
  • [Journal-full-title] No shinkei geka. Neurological surgery
  • [ISO-abbreviation] No Shinkei Geka
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Photosensitizing Agents; 0 / Porphyrins; 88755TAZ87 / Aminolevulinic Acid
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14. Schueller P, Micke O, Palkovic S, Schroeder J, Moustakis C, Bruns F, Schuck A, Wassmann H, Willich N: 12 years' experience with intraoperative radiotherapy (IORT) of malignant gliomas. Strahlenther Onkol; 2005 Aug;181(8):500-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] 12 years' experience with intraoperative radiotherapy (IORT) of malignant gliomas.
  • BACKGROUND: Even after surgery and radiotherapy, malignant gliomas still have a poor prognosis.
  • PATIENTS AND METHODS: From May 1992 to February 2004, 71 patients with malignant gliomas were treated with IORT.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Data Interpretation, Statistical. Disease-Free Survival. Ependymoma / mortality. Ependymoma / radiotherapy. Ependymoma / surgery. Female. Follow-Up Studies. Glioblastoma / mortality. Glioblastoma / radiotherapy. Glioblastoma / surgery. Humans. Intraoperative Period. Male. Middle Aged. Neoplasm Recurrence, Local / radiotherapy. Oligodendroglioma / mortality. Oligodendroglioma / radiotherapy. Oligodendroglioma / surgery. Radiotherapy Dosage. Surgery, Computer-Assisted. Survival Analysis. Time Factors

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  • (PMID = 16044217.001).
  • [ISSN] 0179-7158
  • [Journal-full-title] Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]
  • [ISO-abbreviation] Strahlenther Onkol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
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15. Rodríguez D, Cheung MC, Housri N, Quinones-Hinojosa A, Camphausen K, Koniaris LG: Outcomes of malignant CNS ependymomas: an examination of 2408 cases through the Surveillance, Epidemiology, and End Results (SEER) database (1973-2005). J Surg Res; 2009 Oct;156(2):340-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Outcomes of malignant CNS ependymomas: an examination of 2408 cases through the Surveillance, Epidemiology, and End Results (SEER) database (1973-2005).
  • BACKGROUND: Determine the role of surgery and radiation therapy for patients with malignant CNS ependymomas.
  • RESULTS: Overall, a total of 2408 cases of malignant ependymomas were identified.
  • Of these, 2132 cases (88.5%) were identified as WHO grade II ependymomas and 276 cases (11.5%) as WHO grade III (anaplastic) ependymomas.
  • Univariate analysis demonstrated that age, gender, ethnicity, primary tumor site, WHO grade and surgical resection were significant predictors of improved survival for ependymoma patients.
  • [MeSH-major] Central Nervous System Neoplasms / radiotherapy. Central Nervous System Neoplasms / surgery. Ependymoma / radiotherapy. Ependymoma / surgery
  • [MeSH-minor] Adult. Female. Humans. Male. SEER Program. Treatment Outcome. United States / epidemiology

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  • (PMID = 19577759.001).
  • [ISSN] 1095-8673
  • [Journal-full-title] The Journal of surgical research
  • [ISO-abbreviation] J. Surg. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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16. Tamiolakis D, Papadopoulos N, Venizelos I, Lambropoulou M, Nikolaidou S, Bolioti S, Kiziridou A, Manavis J, Alexiadis G, Simopoulos C: Loss of chromosome 1 in myxopapillary ependymoma suggests a region out of chromosome 22 as critical for tumour biology: a FISH analysis of four cases on touch imprint smears. Cytopathology; 2006 Aug;17(4):199-204
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  • [Title] Loss of chromosome 1 in myxopapillary ependymoma suggests a region out of chromosome 22 as critical for tumour biology: a FISH analysis of four cases on touch imprint smears.
  • We are unaware of any reports involving chromosome 1 aberrations in the malignant progression of ependymomas.
  • [MeSH-major] Brain Neoplasms / genetics. Chromosome Deletion. Chromosomes, Human, Pair 1 / genetics. Chromosomes, Human, Pair 22 / genetics. Ependymoma / genetics
  • [MeSH-minor] Adult. Cytodiagnosis. Humans. In Situ Hybridization, Fluorescence. Male. Middle Aged

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  • (PMID = 16879268.001).
  • [ISSN] 0956-5507
  • [Journal-full-title] Cytopathology : official journal of the British Society for Clinical Cytology
  • [ISO-abbreviation] Cytopathology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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17. Yang XH, Wu QL, Yu XB, Xu CX, Ma BF, Zhang XM, Li SN, Lahn BT, Xiang AP: Nestin expression in different tumours and its relevance to malignant grade. J Clin Pathol; 2008 Apr;61(4):467-73

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nestin expression in different tumours and its relevance to malignant grade.
  • Recently, nestin was detected in some neoplasms such as glioma, ependymoma, melanoma, rhabdomyosarcoma, gastrointestinal stromal tumour (GIST), and testicular stromal tumour.
  • Moreover, the expression intensity of nestin exhibited significant correlation with the malignant grade of glioma.
  • AIMS: To detect the expression of nestin in different tumours and to analyse the relationship between the expression of nestin and the malignant grade of the tumours.
  • There was a statistically significant difference between the histoscore of nestin in high malignant GIST (2.2366 (0.6920)) and that in low malignant GIST (1.3783 (0.4268)) (p = 0.003); and also between that in high malignant angiosarcoma (1.9188 (0.2069)) and that in low malignant angiosarcoma (0.6474 (0.3273)) (p = 0.000).
  • The histoscore of nestin in high malignant pancreatic adenocarcinoma (7/14) was 1.1767 (0.4676), and that in low malignant pancreatic adenocarcinoma (3/8) was 0.6577 (0.0056) (no significant difference, p = 0.112).
  • [MeSH-minor] Adenocarcinoma / metabolism. Adenocarcinoma / pathology. Adult. Aged. Female. Gastrointestinal Stromal Tumors / metabolism. Gastrointestinal Stromal Tumors / pathology. Hemangiosarcoma / metabolism. Hemangiosarcoma / pathology. Humans. Immunoenzyme Techniques. Male. Middle Aged. Nestin. Pancreatic Neoplasms / metabolism. Pancreatic Neoplasms / pathology

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  • (PMID = 17873113.001).
  • [ISSN] 1472-4146
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Intermediate Filament Proteins; 0 / NES protein, human; 0 / Neoplasm Proteins; 0 / Nerve Tissue Proteins; 0 / Nestin
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18. Wang CC, Zhang JT, Liu AL: [Surgical management of brain-stem gliomas: a retrospective analysis of 311 cases]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2005 Feb;27(1):7-12

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Five years survival rate is 67% in ependymoma patients, 42% in astrocytoma patients.
  • For malignant ones, partial removal may prolong survival and facilitate the following combined therapy.
  • [MeSH-major] Astrocytoma / surgery. Brain Stem Neoplasms / surgery. Ependymoma / surgery. Glioblastoma / surgery. Neurosurgical Procedures
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Female. Follow-Up Studies. Humans. Infant. Magnetic Resonance Imaging. Male. Mesencephalon / surgery. Microsurgery / methods. Middle Aged. Pons / surgery. Retrospective Studies. Survival Rate

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  • (PMID = 15782484.001).
  • [ISSN] 1000-503X
  • [Journal-full-title] Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
  • [ISO-abbreviation] Zhongguo Yi Xue Ke Xue Yuan Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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19. Hu WW, Zheng XJ, Shen G, Liu WG, Shen H, Fu WM, Zhou JY: [Diagnosis and micro-neurosurgery for the fourth cerebral ventricle tumors]. Zhonghua Zhong Liu Za Zhi; 2007 Feb;29(2):144-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The pathology included 32 medulloblastomas, 23 ependymoma, 15 astrocytoma, 10 hemangiblastomas, 2 choroid plexus papillomas, and 4 epidermoid cysts.
  • For ependymoma, if close to the brain stem, is recommended to be subtotally removed.
  • Postoperative radiotherapy may be beneficial for malignant types.
  • [MeSH-minor] Adolescent. Adult. Aged. Astrocytoma / diagnosis. Astrocytoma / radiography. Astrocytoma / surgery. Child. Child, Preschool. Combined Modality Therapy. Ependymoma / diagnosis. Ependymoma / radiography. Ependymoma / surgery. Female. Follow-Up Studies. Hemangioblastoma / diagnosis. Hemangioblastoma / radiography. Hemangioblastoma / surgery. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Recurrence, Local. Survival Analysis. Survival Rate. Tomography, X-Ray Computed

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  • (PMID = 17645855.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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20. Onilude OE, Lusher ME, Lindsey JC, Pearson AD, Ellison DW, Clifford SC: APC and CTNNB1 mutations are rare in sporadic ependymomas. Cancer Genet Cytogenet; 2006 Jul 15;168(2):158-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The ependymoma is the second most common malignant brain tumor of childhood; however, its molecular basis is poorly understood.
  • In summary, although inherited APC mutations may be associated with ependymoma development in certain TS2 cases, these data indicate that somatic mutations affecting APC and CTNNB1 do not play a major role in the pathogenesis of sporadic ependymomas.
  • [MeSH-major] Adenomatous Polyposis Coli Protein / genetics. Ependymoma / genetics. Mutation / genetics. beta Catenin / genetics
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Chromatography, High Pressure Liquid. DNA Mutational Analysis. Female. Humans. Male. Middle Aged

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  • (PMID = 16843107.001).
  • [ISSN] 0165-4608
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Adenomatous Polyposis Coli Protein; 0 / CTNNB1 protein, human; 0 / beta Catenin
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21. Rushing EJ, Cooper PB, Quezado M, Begnami M, Crespo A, Smirniotopoulos JG, Ecklund J, Olsen C, Santi M: Subependymoma revisited: clinicopathological evaluation of 83 cases. J Neurooncol; 2007 Dec;85(3):297-305
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The most common mixture (13/15) was subependymoma and ependymoma.
  • [MeSH-major] Cerebral Ventricle Neoplasms / pathology. Ependymoma / pathology. Glioma, Subependymal / pathology. Infratentorial Neoplasms / pathology. Mixed Tumor, Malignant / pathology
  • [MeSH-minor] Adolescent. Adult. Age Factors. Aged. Aged, 80 and over. Child. Child, Preschool. Cohort Studies. Female. Humans. Hydrocephalus / etiology. Hydrocephalus / pathology. Infant. Lateral Ventricles / pathology. Male. Middle Aged. Retrospective Studies. Survival Rate. Treatment Outcome

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  • [Cites] AJNR Am J Neuroradiol. 1995 Nov-Dec;16(10):2121-9 [8585504.001]
  • [Cites] J Comput Assist Tomogr. 1995 Jul-Aug;19(4):518-26 [7622676.001]
  • [Cites] AJR Am J Roentgenol. 1995 Nov;165(5):1245-50 [7572512.001]
  • [Cites] J Neurosurg. 1994 Jun;80(6):1108-11 [8189269.001]
  • [Cites] Mod Pathol. 2004 Mar;17(3):227-87 [14752523.001]
  • [Cites] J Neurosurg. 1983 Dec;59(6):1088-91 [6631507.001]
  • [Cites] Neurosurgery. 2006 May;58(5):881-90; discussion 881-90 [16639322.001]
  • [Cites] Arch Pathol Lab Med. 1999 Apr;123(4):306-9 [10320142.001]
  • [Cites] J Neurooncol. 2005 Mar;72(1):25-8 [15803371.001]
  • [Cites] Mod Pathol. 2005 Jul;18(7):991-7 [15731777.001]
  • [Cites] J Neurosurg. 1991 Oct;75(4):583-8 [1885976.001]
  • [Cites] Cancer Genet Cytogenet. 1999 Jan 1;108(1):84 [9973931.001]
  • [Cites] AJNR Am J Neuroradiol. 1990 Jan-Feb;11(1):83-91 [2105621.001]
  • [Cites] Pathol Int. 2003 Mar;53(3):169-73 [12608898.001]
  • [Cites] Am J Pathol. 1999 Aug;155(2):627-32 [10433955.001]
  • [Cites] Neurosurgery. 1992 Oct;31(4):741-5 [1407461.001]
  • [Cites] J Neurooncol. 2003 Jan;61(1):57-67 [12587796.001]
  • [Cites] Arch Pathol Lab Med. 1999 Oct;123(10):873 [10506435.001]
  • [Cites] J Neurosurg. 1998 Mar;88(3):496-505 [9488304.001]
  • [Cites] J Neurosurg. 1978 Nov;49(5):689-96 [712391.001]
  • [Cites] Neurosurgery. 1986 Oct;19(4):594-8 [3785597.001]
  • [Cites] Clin Neurol Neurosurg. 1997 Feb;99(1):17-22 [9107462.001]
  • [Cites] AJNR Am J Neuroradiol. 1990 May;11(3):567-74 [2349896.001]
  • [Cites] J Neurosurg. 1985 Apr;62(4):508-12 [3973720.001]
  • (PMID = 17569000.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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22. Shrivastava RK, Epstein FJ, Perin NI, Post KD, Jallo GI: Intramedullary spinal cord tumors in patients older than 50 years of age: management and outcome analysis. J Neurosurg Spine; 2005 Mar;2(3):249-55
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECT: Intramedullary spinal cord tumors (IMSCTs) in the older-age adult population pose complex management issues regarding the extent of resection and functional outcome, especially in terms of quality of life.
  • Historically, IMSCTs in the older adult population were treated with irradiation alone because it was assumed that functional recovery would be poor.
  • Ependymoma was the most common tumor (83%), and 55% were located in the thoracic spine.
  • There were two deaths due tumor progression (both malignant tumors) and one recurrence (anaplastic astrocytoma).
  • All three patients in whom malignant astrocytomas were diagnosed underwent postoperative radiation therapy.
  • The longer prodromal period in the older adult population may reflect the fact that their diagnosis and workup is inadequate.
  • [MeSH-major] Ependymoma / surgery. Spinal Cord Neoplasms / surgery

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  • (PMID = 15796348.001).
  • [ISSN] 1547-5654
  • [Journal-full-title] Journal of neurosurgery. Spine
  • [ISO-abbreviation] J Neurosurg Spine
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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23. Garcés-Ambrossi GL, McGirt MJ, Mehta VA, Sciubba DM, Witham TF, Bydon A, Wolinksy JP, Jallo GI, Gokaslan ZL: Factors associated with progression-free survival and long-term neurological outcome after resection of intramedullary spinal cord tumors: analysis of 101 consecutive cases. J Neurosurg Spine; 2009 Nov;11(5):591-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Pathological type included ependymoma in 51 cases, hemangioblastoma in 15, pilocytic astrocytoma in 16, WHO Grade II astrocytoma in 10, and malignant astrocytoma in 9.
  • A GTR resulted in improved PFS for hemangioblastoma (HR 0.004, p = 0.04) and ependymoma (HR 0.2, p = 0.02), but not astrocytoma.
  • A GTR should be attempted for ependymoma and hemangioblastoma, but it may not affect PFS for astrocytoma.
  • [MeSH-minor] Adolescent. Adult. Astrocytoma / mortality. Astrocytoma / pathology. Astrocytoma / surgery. Disease Progression. Disease-Free Survival. Ependymoma / mortality. Ependymoma / pathology. Ependymoma / surgery. Female. Follow-Up Studies. Humans. Kaplan-Meier Estimate. Magnetic Resonance Imaging. Male. Middle Aged. Predictive Value of Tests. Prognosis. Recovery of Function. Retrospective Studies. Risk Factors. Therapeutics. Young Adult

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  • [CommentIn] J Neurosurg Spine. 2009 Nov;11(5):588-9; discussion 590 [19929362.001]
  • (PMID = 19929363.001).
  • [ISSN] 1547-5646
  • [Journal-full-title] Journal of neurosurgery. Spine
  • [ISO-abbreviation] J Neurosurg Spine
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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24. Yang S, Yang X, Hong G: Surgical treatment of one hundred seventy-four intramedullary spinal cord tumors. Spine (Phila Pa 1976); 2009 Nov 15;34(24):2705-10
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  • RESULTS: In this group ependymoma was the commonest tumor (48.9%), the second most often seen being astrocytoma (35.6%).
  • In patients with ependymoma total resection was possible in 92.9% of patients, subtotal in 5.95%, and partial resection in 1.2%.
  • There were 6 patients with malignant astrocytomata; total resection was possible in 1 patient, subtotal resection in 2, and partial resection in 3.In the other tumors total resection was possible in 63% and subtotal in 14.8%, in 23.2% was partial resection possible.
  • For malignant tumors and those where total removal has not been possible radiation therapy is necessary.
  • [MeSH-major] Astrocytoma / surgery. Ependymoma / surgery. Neurosurgical Procedures / methods. Spinal Cord Neoplasms / surgery
  • [MeSH-minor] Activities of Daily Living. Adolescent. Adult. Aged. Child. Child, Preschool. Decompression, Surgical / methods. Disability Evaluation. Early Diagnosis. Female. Humans. Infant. Laminectomy. Magnetic Resonance Imaging. Male. Middle Aged. Outcome Assessment (Health Care). Pain / etiology. Paralysis / etiology. Retrospective Studies. Sensation Disorders / etiology. Treatment Outcome. Urinary Bladder, Neurogenic / etiology. Young Adult

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  • (PMID = 19910775.001).
  • [ISSN] 1528-1159
  • [Journal-full-title] Spine
  • [ISO-abbreviation] Spine
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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25. Nakamura M, Ishii K, Watanabe K, Tsuji T, Matsumoto M, Toyama Y, Chiba K: Long-term surgical outcomes for myxopapillary ependymomas of the cauda equina. Spine (Phila Pa 1976); 2009 Oct 1;34(21):E756-60

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  • SUMMARY OF BACKGROUND DATA: Some patients with myxopapillary ependymoma develop cerebrospinal fluid (CSF) dissemination leading to poor prognosis.
  • CONCLUSION: The results of the present study indicate that the surgical margin obtained at the initial surgery and the extent and amount of postoperative radiation can be crucial factors determining the prognosis of patients with myxopapillary ependymoma.
  • Therefore, early diagnosis is essential, and a therapeutic strategy including radiotherapy, on the assumption that this tumor is malignant, should be established.
  • [MeSH-major] Cauda Equina. Ependymoma / surgery. Neurosurgical Procedures. Peripheral Nervous System Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Female. Humans. Incidence. Longitudinal Studies. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Recurrence, Local / epidemiology. Neoplasm Recurrence, Local / prevention & control. Prognosis. Radiotherapy, Adjuvant / methods. Retrospective Studies. Treatment Outcome. Young Adult

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  • (PMID = 19934795.001).
  • [ISSN] 1528-1159
  • [Journal-full-title] Spine
  • [ISO-abbreviation] Spine
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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26. Strenger V, Sovinz P, Lackner H, Dornbusch HJ, Lingitz H, Eder HG, Moser A, Urban C: Intracerebral cavernous hemangioma after cranial irradiation in childhood. Incidence and risk factors. Strahlenther Onkol; 2008 May;184(5):276-80
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  • BACKGROUND AND PURPOSE: Radiotherapy is an integral part of various therapeutic regimens in pediatric and adult oncology.
  • PATIENTS AND METHODS: Pediatric patients who underwent cranial radiation therapy for malignant diseases between January 1980 and December 2003 were retrospectively analyzed.
  • RESULTS: Of 171 patients, eight (three patients with medulloblastoma, three patients with acute lymphoblastic leukemia, and one patient each with ependymoma and craniopharyngioma) developed intracerebral cavernoma 2.9-18.4 years after irradiation representing a cumulative incidence (according to the Kaplan-Meier method) of 2.24%, 3.86%, 4.95%, and 6.74% within 5, 10, 15, and 20 years following radiation therapy, respectively.
  • [MeSH-minor] Adolescent. Adult. Cerebellar Neoplasms / radiotherapy. Child. Child, Preschool. Craniopharyngioma / radiotherapy. Ependymoma / radiotherapy. Female. Follow-Up Studies. Frontal Lobe / pathology. Frontal Lobe / radiation effects. Humans. Infant. Magnetic Resonance Imaging. Male. Medulloblastoma / radiotherapy. Parietal Lobe / pathology. Parietal Lobe / radiation effects. Pituitary Neoplasms / radiotherapy. Precursor Cell Lymphoblastic Leukemia-Lymphoma / radiotherapy. Radiotherapy Dosage. Risk Factors. Temporal Lobe / pathology. Temporal Lobe / radiation effects. Tomography, X-Ray Computed

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  • (PMID = 18427759.001).
  • [ISSN] 0179-7158
  • [Journal-full-title] Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]
  • [ISO-abbreviation] Strahlenther Onkol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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27. Lasky JL 3rd, Choe M, Nakano I: Cancer stem cells in pediatric brain tumors. Curr Stem Cell Res Ther; 2009 Dec;4(4):298-305
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  • Although recent studies have focused on molecular mechanisms that underlie the initiation and progression of adult glioblastoma multiforme (GBM), these tumors differ phenotypically and at a molecular level from pediatric brain tumors.
  • Recent investigations have identified a stem cell population, termed "brain tumor stem cells" (BTSC) within the heterogeneous cell populations that comprise malignant brain tumors which may be partly responsible for the resistance to current therapies.
  • These have been identified in several pediatric tumors including medulloblastoma, ependymomas, and malignant gliomas.
  • [MeSH-major] Brain Neoplasms / pathology. Ependymoma / pathology. Medulloblastoma / pathology. Neoplastic Stem Cells / pathology. Optic Nerve Glioma / pathology
  • [MeSH-minor] Adult Stem Cells / pathology. Biomarkers / metabolism. Cell Differentiation. Chemotherapy, Adjuvant. Child. Humans. Surgical Procedures, Operative


28. Sandalcioglu IE, Gasser T, Asgari S, Lazorisak A, Engelhorn T, Egelhof T, Stolke D, Wiedemayer H: Functional outcome after surgical treatment of intramedullary spinal cord tumors: experience with 78 patients. Spinal Cord; 2005 Jan;43(1):34-41

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  • A favorable functional outcome was observed in 94.1% of patients with vascular tumors, in 61.3% of patients with low-grade neuroepithelial tumors and in 53.3% of patients with malignant tumors.
  • [MeSH-major] Astrocytoma / surgery. Dermoid Cyst / surgery. Ependymoma / surgery. Hemangioblastoma / surgery. Outcome Assessment (Health Care). Spinal Cord Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Cervical Vertebrae / surgery. Child. Child, Preschool. Female. Germany. Humans. Infant. Lumbar Vertebrae / surgery. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Metastasis / pathology. Postoperative Complications / pathology. Postoperative Complications / physiopathology. Prevalence. Risk Factors. Spinal Cord Compression / etiology. Spinal Cord Compression / surgery. Thoracic Vertebrae / surgery

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  • (PMID = 15326473.001).
  • [ISSN] 1362-4393
  • [Journal-full-title] Spinal cord
  • [ISO-abbreviation] Spinal Cord
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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29. Duda-Szymańska J, Papierz W: Morphological analysis of vascular density in ependymomas. Folia Neuropathol; 2007;45(3):115-9

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  • Density of microvessels was shown to serve in various malignant neoplasms as a prognostic factor that correlates with increased risk of metastasis and overall free survival.
  • The density of blood vessels in anaplastic (WHO G3) ependymomas was shown to be significantly higher than that in WHO G2 type of the tumour, while there was no statistical difference between subtypes of WHO G2 ependymomas.

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  • (PMID = 17849361.001).
  • [ISSN] 1641-4640
  • [Journal-full-title] Folia neuropathologica
  • [ISO-abbreviation] Folia Neuropathol
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Poland
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30. Mangels KJ, Johnson MD, Weil RJ: 35-year-old woman with progressive bilateral leg weakness. Brain Pathol; 2006 Apr;16(2):183-4, 187

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  • PMMTs of the CNS consist of a spectrum of tumors ranging from well-differentiated melanocytoma to its overtly malignant counterpart, melanoma.
  • Once metastasis, including drop metastasis from pigmented medulloblastomas, have been excluded, the differential includes pigmented meningiomas and schwannomas (solitary or as part of Carney complex), as well as other pigmented CNS tumors such as ependymoma and pineoblastoma and systemic diseases such as lymphoma . . .
  • [MeSH-minor] Adult. Female. Functional Laterality. Humans. Thoracic Vertebrae. Treatment Outcome

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  • (PMID = 16768759.001).
  • [ISSN] 1015-6305
  • [Journal-full-title] Brain pathology (Zurich, Switzerland)
  • [ISO-abbreviation] Brain Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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31. Valassi E, Biller BM, Klibanski A, Swearingen B: Clinical features of nonpituitary sellar lesions in a large surgical series. Clin Endocrinol (Oxf); 2010 Dec;73(6):798-807
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  • Twenty-five per cent of malignant lesions were metastases, and some of the MAL (e.g., fibrosarcoma, lung metastasis) had a radiographical appearance suggestive of a pituitary adenoma.

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  • [Copyright] © 2010 Blackwell Publishing Ltd.
  • [Cites] J Clin Endocrinol Metab. 1999 Nov;84(11):3972-82 [10566636.001]
  • [Cites] J Neurosurg. 2005 Apr;102(4):650-7 [15871507.001]
  • [Cites] Endocrinol Metab Clin North Am. 2003 Jun;32(2):355-65 [12800536.001]
  • [Cites] J Clin Endocrinol Metab. 2003 Oct;88(10):4709-19 [14557445.001]
  • [Cites] J Neurosurg. 2004 Jan;100(1):33-40 [14743909.001]
  • [Cites] Am J Ophthalmol. 2004 May;137(5):908-13 [15126157.001]
  • [Cites] J Neurosurg. 2004 Oct;101(4):577-84 [15481709.001]
  • [Cites] J Neurosurg. 1966 Jan;24(1):77-81 [5903300.001]
  • [Cites] J Neurosurg. 1968 Jun;28(6):595-9 [5671296.001]
  • [Cites] Acta Neuropathol. 1980;50(3):199-205 [7415813.001]
  • [Cites] Surg Neurol. 1982 Dec;18(6):448-51 [7163965.001]
  • [Cites] J Clin Endocrinol Metab. 1987 Sep;65(3):469-74 [3624409.001]
  • [Cites] Endocrinol Metab Clin North Am. 1987 Sep;16(3):647-65 [3319597.001]
  • [Cites] Br J Neurosurg. 1989;3(1):71-9 [2789715.001]
  • [Cites] J Neurosurg. 1991 Apr;74(4):535-44 [2002366.001]
  • [Cites] Am J Ophthalmol. 1995 Jun;119(6):779-85 [7785694.001]
  • [Cites] Neurosurgery. 1995 Oct;37(4):649-53; discussion 653-4 [8559292.001]
  • [Cites] J Clin Endocrinol Metab. 1996 Oct;81(10):3455-9 [8855784.001]
  • [Cites] Neurosurgery. 1997 Feb;40(2):225-36; discussion 236-7 [9007854.001]
  • [Cites] Surg Neurol. 1997 May;47(5):447-52; discussion 452-4 [9131027.001]
  • [Cites] J Clin Endocrinol Metab. 1997 Jul;82(7):2357-62 [9215319.001]
  • [Cites] J Neurosurg. 1997 Oct;87(4):499-507 [9322839.001]
  • [Cites] J Neurosurg. 1999 Feb;90(2):237-50 [9950494.001]
  • [Cites] J Neurosurg. 1999 Feb;90(2):251-7 [9950495.001]
  • [Cites] Radiol Clin North Am. 1999 Jan;37(1):101-21, x [10026732.001]
  • [Cites] J Neurosurg. 2005 Sep;103(3):448-54 [16235676.001]
  • [Cites] Neurol Clin. 2007 Nov;25(4):1231-49, xi [17964033.001]
  • [Cites] Hum Pathol. 2009 Mar;40(3):435-40 [18992914.001]
  • [Cites] Clin Endocrinol (Oxf). 1999 Apr;50(4):431-9 [10468901.001]
  • [Cites] Ann Med Interne (Paris). 1999 Jun;150(4):327-41 [10519020.001]
  • [Cites] J Neurosurg. 2002 Jul;97(1):3-11 [12134929.001]
  • (PMID = 20874772.001).
  • [ISSN] 1365-2265
  • [Journal-full-title] Clinical endocrinology
  • [ISO-abbreviation] Clin. Endocrinol. (Oxf)
  • [Language] ENG
  • [Grant] United States / NCRR NIH HHS / RR / RR025758-027208; United States / NCRR NIH HHS / RR / UL1 RR025758; United States / NCRR NIH HHS / RR / UL1 RR025758-027208; United States / NCRR NIH HHS / RR / ULI RR0257801
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Other-IDs] NLM/ NIHMS240981; NLM/ PMC2982869
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32. Stark AM, Maslehaty H, Hugo HH, Mahvash M, Mehdorn HM: Glioblastoma of the cerebellum and brainstem. J Clin Neurosci; 2010 Oct;17(10):1248-51
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  • Glioblastoma multiforme (GB) is the most common and most malignant primary intracranial tumor.
  • Because of its rarity and the non-specific radiological features of iGB, it can easily be misdiagnosed as a brain metastasis, ependymoma or even as a benign lesion such as vestibular schwannoma or meningioma.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Magnetic Resonance Imaging / methods. Male. Middle Aged. Retrospective Studies. Young Adult

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  • [Copyright] Copyright 2010 Elsevier Ltd. All rights reserved.
  • (PMID = 20619657.001).
  • [ISSN] 1532-2653
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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33. Pinker K, Noebauer-Huhmann IM, Stavrou I, Hoeftberger R, Szomolanyi P, Weber M, Stadlbauer A, Grabner G, Knosp E, Trattnig S: High-field, high-resolution, susceptibility-weighted magnetic resonance imaging: improved image quality by addition of contrast agent and higher field strength in patients with brain tumors. Neuroradiology; 2008 Jan;50(1):9-16
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  • INTRODUCTION: To demonstrate intratumoral susceptibility effects in malignant brain tumors and to assess visualization of susceptibility effects before and after administration of the paramagnetic contrast agent MultiHance (gadobenate dimeglumine; Bracco Imaging), an agent known to have high relaxivity, with respect to susceptibility effects, image quality, and reduction of scan time.
  • METHODS: Included in the study were 19 patients with malignant brain tumors who underwent high-resolution, susceptibility-weighted (SW) MR imaging at 3 T before and after administration of contrast agent.
  • [MeSH-minor] Adult. Aged. Astrocytoma / diagnosis. Brain / pathology. Efficiency. Ependymoma / diagnosis. Female. Glioblastoma / diagnosis. Humans. Male. Middle Aged. Oligodendroglioma / diagnosis. Plasmacytoma / diagnosis. Sensitivity and Specificity

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  • [Cites] J Magn Reson Imaging. 2006 Jul;24(1):41-51 [16755540.001]
  • [Cites] J Magn Reson Imaging. 2005 Oct;22(4):439-50 [16163700.001]
  • [Cites] Neuroradiology. 2001 May;43(5):364-9 [11396739.001]
  • [Cites] NMR Biomed. 2001 Nov-Dec;14(7-8):453-67 [11746938.001]
  • [Cites] Invest Radiol. 2003 Jul;38(7):409-14 [12821854.001]
  • [Cites] Invest Radiol. 1999 Jun;34(6):427-34 [10353036.001]
  • [Cites] MAGMA. 1998 Aug;6(1):62-9 [9794291.001]
  • [Cites] Invest Radiol. 2002 Mar;37(3):114-9 [11882790.001]
  • [Cites] Radiology. 1997 Feb;202(2):511-6 [9015082.001]
  • [Cites] Invest Radiol. 2006 Mar;41(3):249-55 [16481907.001]
  • [Cites] J Comput Assist Tomogr. 2000 Nov-Dec;24(6):949-57 [11105717.001]
  • [Cites] J Magn Reson Imaging. 1999 Aug;10(2):118-23 [10441013.001]
  • (PMID = 17876570.001).
  • [ISSN] 1432-1920
  • [Journal-full-title] Neuroradiology
  • [ISO-abbreviation] Neuroradiology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Organometallic Compounds; 15G12L5X8K / gadobenic acid; 6HG8UB2MUY / Meglumine
  •  go-up   go-down


34. Wöhrer A, Waldhör T, Heinzl H, Hackl M, Feichtinger J, Gruber-Mösenbacher U, Kiefer A, Maier H, Motz R, Reiner-Concin A, Richling B, Idriceanu C, Scarpatetti M, Sedivy R, Bankl HC, Stiglbauer W, Preusser M, Rössler K, Hainfellner JA: The Austrian Brain Tumour Registry: a cooperative way to establish a population-based brain tumour registry. J Neurooncol; 2009 Dec;95(3):401-411
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  • In Austria, registration of malignant brain tumours is legally mandatory, whereas benign and borderline tumours are not reported.
  • The Austrian Brain Tumour Registry (ABTR) was initiated under the auspices of the Austrian Society of Neuropathology for the registration of malignant and non-malignant brain tumours.
  • Non-malignant cases constituted 866 cases (51.3%).
  • [MeSH-minor] Adenoma / epidemiology. Adenoma / pathology. Adolescent. Adult. Age Distribution. Aged. Aged, 80 and over. Austria / epidemiology. Child. Child, Preschool. Ependymoma / epidemiology. Ependymoma / pathology. Female. Geographic Information Systems. Humans. Incidence. Male. Meningeal Neoplasms / epidemiology. Meningeal Neoplasms / pathology. Middle Aged. Oligodendroglioma / epidemiology. Oligodendroglioma / pathology. Reproducibility of Results. Sex Distribution. Young Adult

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  • [Cites] Int J Cancer. 2004 Jan 20;108(3):450-5 [14648713.001]
  • [Cites] J Neurooncol. 1999 May;42(3):195-204 [10433103.001]
  • [Cites] J Clin Oncol. 2000 Jan;18(2):348-57 [10637249.001]
  • [Cites] Br J Cancer. 2005 Oct 3;93(7):842-8 [16136046.001]
  • [Cites] Epidemiology. 2004 Nov;15(6):653-9 [15475713.001]
  • [Cites] Neuro Oncol. 2002 Oct;4(4):278-99 [12356358.001]
  • [Cites] J Clin Oncol. 2007 Sep 10;25(26):4104-9 [17827460.001]
  • [Cites] Neurol Clin. 2007 Nov;25(4):925-46, viii [17964021.001]
  • [Cites] AIDS Read. 2000 Aug;10(8):486-91 [10967810.001]
  • [Cites] Dis Nerv Syst. 1967 Feb;28(2):89-93 [5336568.001]
  • [Cites] Neurosurgery. 1987 Jul;21(1):21-6 [3039398.001]
  • [Cites] Neurosurgery. 1994 Jan;34(1):68-78 [8121571.001]
  • [Cites] Neurosurg Focus. 2005 Apr 15;18(4):e12 [15844864.001]
  • [Cites] J Natl Cancer Inst. 1998 Oct 7;90(19):1473-9 [9776413.001]
  • [Cites] J Epidemiol Biostat. 2000;5(2):99-107 [10890281.001]
  • [Cites] Acta Neuropathol. 2007 Aug;114(2):97-109 [17618441.001]
  • [Cites] J Neurooncol. 2007 Sep;84(2):189-99 [17431547.001]
  • [Cites] J Neurooncol. 1994;18(1):69-81 [8057137.001]
  • [Cites] J Neurooncol. 2002 Oct;60(1):61-9 [12416547.001]
  • [Cites] Int J Oncol. 2008 May;32(5):1097-103 [18425337.001]
  • [Cites] Surg Neurol. 2006 Sep;66(3):258-63; discussion 263 [16935629.001]
  • [Cites] Neuro Oncol. 2006 Jan;8(1):27-37 [16443945.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2008 Mar;17(3):484-9 [18349266.001]
  • [Cites] N Engl J Med. 2005 Mar 10;352(10 ):997-1003 [15758010.001]
  • [Cites] Neuroepidemiology. 2006;27(1):22-7 [16770081.001]
  • [Cites] Int J Clin Oncol. 2008 Apr;13(2):90-6 [18463950.001]
  • [Cites] Radiat Res. 2005 Apr;163(4):424-32 [15799699.001]
  • [Cites] N Engl J Med. 2005 Mar 10;352(10 ):987-96 [15758009.001]
  • [Cites] N Engl J Med. 2001 Jan 11;344(2):79-86 [11150357.001]
  • (PMID = 19562257.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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35. Lujan-Castilla PJ, Durán-Cruz M, Enríquez-Barrera M, García-Muñóz L, Hernández-Oviedo JO, Barragán-Pérez JA: [Stereotactic radiosurgery with linear accelerator (LINAC). Report of the technical experience in 100 cases treated at the Mexico General Hospital]. Gac Med Mex; 2005 Sep-Oct;141(5):367-82
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  • METHODS: One hundred patients received treatment with LINAC stereotactic radiosurgery, 34 AVM, 22 meningiomas, 18 astrocytomas, 11 pituitary adenomas, 5 cavernous malformations, 3 acoustic neuromas, 3 craniopharyngiomas, 2 cases of epilepsy, one brain metastasis and one ependymoma.
  • CONCLUSIONS: Radiosurgery is a safe and reliable technique to treat benign and malignant intracraneal lesions.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Female. Hospitals, General. Humans. Male. Mexico. Middle Aged

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  • (PMID = 16353882.001).
  • [ISSN] 0016-3813
  • [Journal-full-title] Gaceta médica de México
  • [ISO-abbreviation] Gac Med Mex
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Mexico
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36. Igaz P: MEN1 clinical background. Adv Exp Med Biol; 2009;668:1-15
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  • Beside these three, several other endocrine (adrenocortical, foregut carcinoid) and nonendocrine (lipoma, angiofibroma, collagenoma, ependymoma, meningioma) tumors have been described to be associated with this syndrome.
  • Both benign (parathyroid, anterior pituitary) and malignant (gastrinoma, glucagonoma) lesions may develop in MEN1 patients.
  • [MeSH-minor] Adult. Child. Child, Preschool. Diagnosis, Differential. Genetic Predisposition to Disease. Genetic Testing. Humans. Middle Aged. Multiple Endocrine Neoplasia Type 2a / genetics. Multiple Endocrine Neoplasia Type 2a / pathology. Multiple Endocrine Neoplasia Type 2a / physiopathology. Mutation. Young Adult

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  • (PMID = 20175448.001).
  • [ISSN] 0065-2598
  • [Journal-full-title] Advances in experimental medicine and biology
  • [ISO-abbreviation] Adv. Exp. Med. Biol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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37. Adam Y, Benezech J, Blanquet A, Fuentes JM, Bousigue JY, Debono B, Duplessis E, Espagno C, Plas JY, Lescure JP, Destandau J, Hladky JP, Grunewald P, Mahla K, Remond J, Louis E: [Intramedullary tumors. Results of a national investigation in private neurosurgery]. Neurochirurgie; 2010 Aug;56(4):344-9

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  • Tumor removal was complete in the cases of ependymoma and hemangioblastoma and subtotal in the cases of astrocytoma.
  • RESULTS: Ependymoma: 38 cases with three cases of ependymoblastoma.
  • Astrocytomas: 22 cases, with 14 cases of astrocytoma, two pilocytic astrocytoma, four malignant astrocytoma, and two glioblastoma.
  • Diagnostic delay: malignant tumors, one to nine months; low grades; three to six years (range, eight months to 25 years).
  • [MeSH-minor] Adolescent. Adult. Aged. Delayed Diagnosis. Female. Follow-Up Studies. France / epidemiology. Humans. Magnetic Resonance Imaging. Male. Microsurgery. Middle Aged. Neoplasm Recurrence, Local. Neurosurgical Procedures. Treatment Outcome. Young Adult

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  • [Copyright] Copyright (c) 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20097390.001).
  • [ISSN] 1773-0619
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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38. Hoffman S, Schellinger KA, Propp JM, McCarthy BJ, Campbell RT, Davis FG: Seasonal variation in incidence of pediatric medulloblastoma in the United States, 1995-2001. Neuroepidemiology; 2007;29(1-2):89-95
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  • The literature suggests that one of the most common subtypes of malignant childhood brain tumor, medulloblastoma, has some seasonal variation in incidence by month of birth.
  • There were no significant results for brain tumors overall, or for the other most common pediatric tumor subtypes (pilocytic astrocytoma, other astrocytoma, and ependymoma).
  • [MeSH-minor] Adolescent. Adult. Birth Rate. Child. Child, Preschool. Female. Humans. Incidence. Male. Registries. United States / epidemiology

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  • [Copyright] (c) 2007 S. Karger AG, Basel.
  • (PMID = 17925600.001).
  • [ISSN] 1423-0208
  • [Journal-full-title] Neuroepidemiology
  • [ISO-abbreviation] Neuroepidemiology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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39. Mühlisch J, Bajanowski T, Rickert CH, Roggendorf W, Würthwein G, Jürgens H, Frühwald MC: Frequent but borderline methylation of p16 (INK4a) and TIMP3 in medulloblastoma and sPNET revealed by quantitative analyses. J Neurooncol; 2007 May;83(1):17-29
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  • Aberrant methylation is common in malignant brain tumors of childhood and may have implications for stratification and therapy.
  • Methylation of p16 (INK4A), p14 (ARF), TIMP3, CDH1, p15 (INK4B )and DAPK1 in medulloblastoma (MB) and ependymoma has been discussed controversially in the literature.
  • We examined methylation in MB, sPNET and ependymoma using methylation-specific PCR (MSP), quantitative Combined Bisulfite Restriction Analysis (COBRA) and direct and clone sequencing of bisulfite PCR products.
  • Only p16 (INK4A )and TIMP3 were methylated consistently in medulloblastomas (p16 (INK4A ) 14%, TIMP3 11%) and p16 (INK4A) also in anaplastic ependymomas (1/4 tumors).
  • [MeSH-minor] Adolescent. Adult. Aged. Apoptosis Regulatory Proteins / genetics. Calcium-Calmodulin-Dependent Protein Kinases / genetics. Child. Child, Preschool. Death-Associated Protein Kinases. Female. Gene Silencing. Humans. Infant. Male. Middle Aged. Nerve Tissue Proteins / genetics. Receptors, Immunologic / genetics

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  • [Cites] Oncogene. 2002 Feb 7;21(7):1048-61 [11850822.001]
  • [Cites] Clin Orthop Relat Res. 2006 Jan;442:216-22 [16394764.001]
  • [Cites] Oncogene. 2001 Aug 16;20(36):5033-42 [11526488.001]
  • [Cites] Int J Cancer. 2000 Jun 1;86(5):632-5 [10797283.001]
  • [Cites] Carcinogenesis. 2004 May;25(5):661-8 [14688019.001]
  • [Cites] Proc Natl Acad Sci U S A. 1996 Sep 3;93(18):9821-6 [8790415.001]
  • [Cites] Biotechniques. 1995 Jul;19(1):116-21 [7669285.001]
  • [Cites] Cancer Res. 1999 Feb 15;59(4):798-802 [10029065.001]
  • [Cites] APMIS. 2003 Nov;111(11):1067-74 [14629273.001]
  • [Cites] Mol Cell Biol. 1993 Dec;13(12):7372-9 [7504173.001]
  • [Cites] Cancer Res. 2004 Jun 1;64(11):3871-7 [15172996.001]
  • [Cites] Cancer Res. 2004 Aug 1;64(15):5511-7 [15289362.001]
  • [Cites] Nucleic Acids Res. 2001 Nov 15;29(22):4598-606 [11713309.001]
  • [Cites] Cell. 1996 Apr 5;85(1):27-37 [8620534.001]
  • [Cites] Cancer Res. 2002 Feb 15;62(4):1148-51 [11861396.001]
  • [Cites] Biochem Biophys Res Commun. 2004 Jun 25;319(2):697-704 [15178462.001]
  • [Cites] Cancer Genet Cytogenet. 2006 Apr 1;166(1):74-81 [16616114.001]
  • [Cites] Pharmacogenomics J. 2002;2(1):7-10 [11990385.001]
  • [Cites] Methods. 2001 Dec;25(4):456-62 [11846615.001]
  • [Cites] Int J Cancer. 1999 Oct 29;83(3):309-13 [10495421.001]
  • [Cites] Anal Biochem. 2004 Oct 1;333(1):119-27 [15351288.001]
  • [Cites] Cell. 2001 Sep 7;106(5):531-4 [11551500.001]
  • [Cites] Int J Mol Med. 2003 May;11(5):655-60 [12684707.001]
  • [Cites] Mol Cell Biol. 1997 Oct;17(10):5897-904 [9315647.001]
  • [Cites] Genomics. 1999 Jun 15;58(3):254-62 [10373323.001]
  • [Cites] Oncogene. 2002 Jun 20;21(27):4345-9 [12082624.001]
  • [Cites] Mol Cell Biol. 1994 Aug;14(8):5487-94 [7518564.001]
  • [Cites] J Med Genet. 2000 Jul;37(7):501-9 [10882752.001]
  • [Cites] Cancer Res. 2001 Apr 1;61(7):2816-21 [11306450.001]
  • [Cites] Trends Genet. 2000 Jun;16(6):276-7 [10827456.001]
  • [Cites] Neurosurg Focus. 2005 Nov 15;19(5):E10 [16398460.001]
  • [Cites] Clin Cancer Res. 2006 Aug 1;12 (15):4738-46 [16899625.001]
  • [Cites] Pediatr Neurosurg. 2003 Jul;39(2):60-7 [12845195.001]
  • [Cites] Genes Chromosomes Cancer. 2001 Jan;30(1):38-47 [11107174.001]
  • [Cites] Oncogene. 2006 Feb 16;25(7):1111-7 [16186793.001]
  • [Cites] Biotechniques. 1996 Jul;21(1):126-33 [8816247.001]
  • [Cites] J Clin Oncol. 2006 Jul 20;24(21):3431-7 [16849758.001]
  • [Cites] Neuropathol Appl Neurobiol. 2003 Dec;29(6):574-83 [14636164.001]
  • [Cites] PLoS Biol. 2004 Dec;2(12):e405 [15550986.001]
  • [Cites] Pathol Oncol Res. 2004;10(1):17-21 [15029256.001]
  • [Cites] Neuropathol Appl Neurobiol. 2002 Aug;28(4):257-82 [12175339.001]
  • [Cites] Cancer Cell. 2004 Oct;6(4):387-98 [15488761.001]
  • [Cites] Cancer Genet Cytogenet. 2003 Jul 15;144(2):134-42 [12850376.001]
  • [Cites] J Pediatr Hematol Oncol. 1997 Nov-Dec;19(6):492-501 [9407934.001]
  • [Cites] Bioinformatics. 2004 Nov 22;20(17):3005-12 [15247106.001]
  • [Cites] N Engl J Med. 2005 Mar 10;352(10 ):997-1003 [15758010.001]
  • [Cites] Nat Med. 2003 Apr;9(4):407-15 [12652295.001]
  • [Cites] Pediatr Blood Cancer. 2007 Apr;48(4):403-7 [16609952.001]
  • [Cites] Clin Cancer Res. 2002 Jul;8(7):2217-24 [12114423.001]
  • [Cites] Nat Genet. 2000 Feb;24(2):132-8 [10655057.001]
  • [Cites] Nature. 2001 Feb 15;409(6822):860-921 [11237011.001]
  • (PMID = 17206475.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Apoptosis Regulatory Proteins; 0 / Nerve Tissue Proteins; 0 / Receptors, Immunologic; 0 / TIMP3 protein, human; 0 / Tissue Inhibitor of Metalloproteinase-3; 0 / roundabout protein; EC 2.7.11.1 / DAPK1 protein, human; EC 2.7.11.1 / Death-Associated Protein Kinases; EC 2.7.11.17 / Calcium-Calmodulin-Dependent Protein Kinases
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40. Barnholtz-Sloan JS, Severson RK, Stanton B, Hamre M, Sloan AE: Pediatric brain tumors in non-Hispanics, Hispanics, African Americans and Asians: differences in survival after diagnosis. Cancer Causes Control; 2005 Jun;16(5):587-92
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  • METHODS: Subjects identified through the SEER Program were 2799 children, < or =19 years old at diagnosis, newly diagnosed between 1973 and 1996 with primary, malignant brain tumors.
  • [MeSH-minor] Adolescent. Adult. Astrocytoma / ethnology. Astrocytoma / mortality. Astrocytoma / therapy. Child. Child, Preschool. Ependymoma / ethnology. Ependymoma / mortality. Ependymoma / therapy. Female. Humans. Infant. Infant, Newborn. Male. Medulloblastoma / ethnology. Medulloblastoma / mortality. Medulloblastoma / therapy. Proportional Hazards Models. SEER Program. Survival Analysis. United States / epidemiology

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  • (PMID = 15986114.001).
  • [ISSN] 0957-5243
  • [Journal-full-title] Cancer causes & control : CCC
  • [ISO-abbreviation] Cancer Causes Control
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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41. Kashyap R, Ryan C, Sharma R, Maloo MK, Safadjou S, Graham M, Tretheway D, Jain A, Orloff M: Liver grafts from donors with central nervous system tumors: a single-center perspective. Liver Transpl; 2009 Oct;15(10):1204-8
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  • Thirty-two tumors were malignant, and 10 tumors were benign.
  • Twenty (47.6%) of the CNS tumors were glioblastoma multiforme (astrocytoma grade IV), 11 (26.2%) were other astrocytomas, and 1 (2.4%) was an anaplastic ependymoma.
  • [MeSH-minor] Adult. Blood-Brain Barrier. Female. Humans. Male. Middle Aged. Neoplasm Metastasis. Retrospective Studies. Time Factors. Tissue Donors. Treatment Outcome

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  • [Copyright] Copyright 2009 AASLD
  • [CommentIn] Liver Transpl. 2010 Jul;16(7):916 [20583090.001]
  • [CommentIn] Liver Transpl. 2010 Jul;16(7):914-5 [20583288.001]
  • (PMID = 19790151.001).
  • [ISSN] 1527-6473
  • [Journal-full-title] Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
  • [ISO-abbreviation] Liver Transpl.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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42. Goldhoff P, Warrington NM, Limbrick DD Jr, Hope A, Woerner BM, Jackson E, Perry A, Piwnica-Worms D, Rubin JB: Targeted inhibition of cyclic AMP phosphodiesterase-4 promotes brain tumor regression. Clin Cancer Res; 2008 Dec 1;14(23):7717-25
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  • PURPOSE: As favorable outcomes from malignant brain tumors remain limited by poor survival and treatment-related toxicity, novel approaches to cure are essential.
  • RESULTS: We found that PDE4A is expressed in medulloblastoma, glioblastoma, oligodendroglioma, ependymoma, and meningioma.
  • In long-term survival and bioluminescence studies, Rolipram in combination with first-line therapy for malignant gliomas (temozolomide and conformal radiation therapy) enhanced the survival of mice bearing intracranial xenografts of U87 glioblastoma cells.

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  • [Cites] Cancer Res. 2005 Dec 15;65(24):11392-9 [16357147.001]
  • [Cites] Drug Discov Today. 2005 Nov 15;10(22):1503-19 [16257373.001]
  • [Cites] Mol Cell Biol. 2006 Mar;26(5):1666-78 [16478988.001]
  • [Cites] Expert Rev Anticancer Ther. 2006 May;6(5):733-54 [16759164.001]
  • [Cites] Biochem Soc Trans. 2006 Aug;34(Pt 4):504-9 [16856845.001]
  • [Cites] Clin Cancer Res. 2006 Aug 1;12(15):4738-46 [16899625.001]
  • [Cites] J Cell Sci. 2006 Sep 15;119(Pt 18):3799-810 [16940352.001]
  • [Cites] Pharmacol Rev. 2006 Sep;58(3):488-520 [16968949.001]
  • [Cites] Curr Top Dev Biol. 2006;75:225-59 [16984814.001]
  • [Cites] Cancer Res. 2007 Jan 15;67(2):651-8 [17234775.001]
  • [Cites] Cancer Res. 2007 Jun 1;67(11):5248-57 [17545604.001]
  • [Cites] Cancer Res. 2007 Sep 15;67(18):8588-95 [17875698.001]
  • [Cites] Chem Res Toxicol. 2000 Oct;13(10):944-8 [11080038.001]
  • [Cites] Cell Signal. 2001 Dec;13(12):911-8 [11728831.001]
  • [Cites] Science. 2002 Feb 1;295(5556):868-72 [11786607.001]
  • [Cites] J Biol Chem. 2002 Aug 2;277(31):28298-309 [11994273.001]
  • [Cites] Cancer Biol Ther. 2002 May-Jun;1(3):268-76 [12432276.001]
  • [Cites] Biochem J. 2003 Feb 15;370(Pt 1):1-18 [12444918.001]
  • [Cites] Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13513-8 [14595012.001]
  • [Cites] J Neurosurg. 1977 Apr;46(4):477-83 [191576.001]
  • [Cites] J Neurooncol. 1983;1(1):61-7 [6086852.001]
  • [Cites] Pharmacopsychiatry. 1984 Nov;17(6):188-90 [6393150.001]
  • [Cites] Biochem J. 1993 Jun 15;292 ( Pt 3):677-86 [7686364.001]
  • [Cites] Cancer Res. 1993 Jul 1;53(13):3058-61 [8391385.001]
  • [Cites] Biochem J. 1995 Jun 1;308 ( Pt 2):673-81 [7772057.001]
  • [Cites] Eur J Cancer. 1995;31A(5):714-7 [7640043.001]
  • [Cites] Biochem J. 1995 Sep 15;310 ( Pt 3):965-74 [7575434.001]
  • [Cites] J Neurooncol. 1997 Apr;32(2):161-8 [9120546.001]
  • [Cites] Neurosci Lett. 1998 Mar 6;244(1):41-6 [9578140.001]
  • [Cites] Biochem J. 1998 Aug 1;333 ( Pt 3):693-703 [9677330.001]
  • [Cites] J Med Chem. 1998 Nov 19;41(24):4733-43 [9822544.001]
  • [Cites] Brain Pathol. 1999 Jul;9(3):469-79 [10416987.001]
  • [Cites] Cancer Res. 2004 Dec 1;64(23):8604-12 [15574767.001]
  • [Cites] N Engl J Med. 2005 Mar 10;352(10):997-1003 [15758010.001]
  • [Cites] N Engl J Med. 2005 Mar 10;352(10):1036-8 [15758016.001]
  • [Cites] Cell Signal. 2005 Sep;17(9):1158-73 [15905070.001]
  • [Cites] J Immunol. 2005 Aug 1;175(3):1523-31 [16034090.001]
  • [Cites] Arch Toxicol. 2006 Feb;80(2):88-97 [16167140.001]
  • [Cites] Nat Methods. 2005 Aug;2(8):607-14 [16094386.001]
  • [Cites] J Biol Chem. 2005 Sep 30;280(39):33178-89 [16030021.001]
  • [CommentIn] Clin Cancer Res. 2009 May 1;15(9):3238; author reply 3238-9 [19406836.001]
  • (PMID = 19047098.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P50 CA094056; United States / NINDS NIH HHS / NS / P30 NS057105; United States / NCI NIH HHS / CA / P30 CA91842; United States / NCI NIH HHS / CA / P30 CA091842; United States / NCI NIH HHS / CA / R21 CA108677; United States / NCI NIH HHS / CA / P50 CA94056; United States / NCI NIH HHS / CA / P50 CA094056-01
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Phosphodiesterase Inhibitors; 7GR28W0FJI / Dacarbazine; 85622-93-1 / temozolomide; EC 3.1.4.17 / Cyclic Nucleotide Phosphodiesterases, Type 4; K676NL63N7 / Rolipram
  • [Other-IDs] NLM/ NIHMS82831; NLM/ PMC2615415
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43. Badruddoja MA, Keir ST, King I, Zeidner J, Vredenburgh JJ, Muhlbaier LH, Bigner DD, Friedman HS: Activity of VNP40101M (Cloretazine) in the treatment of CNS tumor xenografts in athymic mice. Neuro Oncol; 2007 Jul;9(3):240-4
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  • The current study was designed to assess the activity of VNP40101M administered at a dose of 18 mg/kg daily for five days against a panel of human adult and pediatric CNS tumors growing subcutaneously or intracranially in athymic nude mice.
  • The results demonstrated statistically significant (p < 0.05) growth delays of 15.0, 8.3, 51.0, 60+, 60+, and 60+ days in subcutaneous xenografts derived from childhood glioblastoma multiforme (D-456 MG), childhood ependymoma (D-528 EP and D-612 EP), childhood medulloblastoma (D-425 MED), and adult malignant glioma (D-245 MG and D-54 MG), respectively, with corresponding tumor regressions in 10 of 10, 4 of 10, 8 of 10, 9 of 10, 9 of 10, and 10 of 10 treated mice, respectively.

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  • [Cites] Cancer Chemother Pharmacol. 1994;34(2):171-4 [8194169.001]
  • [Cites] Proc Natl Acad Sci U S A. 1990 Jul;87(14):5368-72 [2164681.001]
  • [Cites] Cancer Res. 1995 Jul 1;55(13):2853-7 [7796412.001]
  • [Cites] Cancer Res. 1997 Jul 15;57(14):2933-6 [9230204.001]
  • [Cites] Invest New Drugs. 2005 Mar;23(2):123-35 [15744588.001]
  • [Cites] N Engl J Med. 2005 Mar 10;352(10):987-96 [15758009.001]
  • [Cites] Biochem Pharmacol. 2000 Feb 1;59(3):283-91 [10609557.001]
  • [Cites] Cancer Res. 2001 Apr 1;61(7):3033-8 [11306484.001]
  • [Cites] Int J Toxicol. 2002 Jan-Feb;21(1):23-38 [11936896.001]
  • [Cites] Cancer Chemother Pharmacol. 2004 Apr;53(4):288-95 [14685775.001]
  • [Cites] Clin Cancer Res. 2004 May 1;10(9):2908-17 [15131024.001]
  • [Cites] Anal Biochem. 1976 May 7;72:248-54 [942051.001]
  • [Cites] Neurosurgery. 1979 Apr;4(4):308-14 [450229.001]
  • [Cites] Cancer Res. 1988 Aug 1;48(15):4189-95 [3390813.001]
  • [Cites] J Neurooncol. 1994;20(2):111-20 [7807189.001]
  • (PMID = 17522334.001).
  • [ISSN] 1522-8517
  • [Journal-full-title] Neuro-oncology
  • [ISO-abbreviation] Neuro-oncology
  • [Language] ENG
  • [Grant] United States / NINDS NIH HHS / NS / P50 NS020023; United States / NINDS NIH HHS / NS / 5P50-NS20023-23
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Hydrazines; 0 / Prodrugs; 0 / Sulfonamides; 14J2G0U3NQ / laromustine
  • [Other-IDs] NLM/ PMC1907418
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44. Sterzing F, Schubert K, Sroka-Perez G, Kalz J, Debus J, Herfarth K: Helical tomotherapy. Experiences of the first 150 patients in Heidelberg. Strahlenther Onkol; 2008 Jan;184(1):8-14

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  • Most common tumor entities were prostate cancer (n = 28), breast cancer (n = 17), gastrointestinal tumors (n = 19), pharyngeal carcinoma (n = 14), lymphoma (n = 13), metastatic disease (bone n = 14, liver n = 6, lung n = 4, lymph node n = 2), sarcoma (n = 8), malignant pleural mesothelioma (n = 5), ovarian cancer treated with whole abdominal irradiation (n = 4), lung cancer (n = 3), skin malignancies (n = 3), chordoma (n = 2), meningioma (n = 2), one ependymoma and one medulloblastoma treated with craniospinal axis irradiation (n = 2), and others (n = 4).
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Combined Modality Therapy. Dose Fractionation. Female. Humans. Male. Middle Aged. Radiotherapy, Adjuvant. Radiotherapy, Conformal / methods. Technology Assessment, Biomedical

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  • (PMID = 18188517.001).
  • [ISSN] 0179-7158
  • [Journal-full-title] Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]
  • [ISO-abbreviation] Strahlenther Onkol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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45. Neuwelt EA, Gilmer-Knight K, Lacy C, Nicholson HS, Kraemer DF, Doolittle ND, Hornig GW, Muldoon LL: Toxicity profile of delayed high dose sodium thiosulfate in children treated with carboplatin in conjunction with blood-brain-barrier disruption. Pediatr Blood Cancer; 2006 Aug;47(2):174-82
Hazardous Substances Data Bank. SODIUM THIOSULFATE .

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  • PURPOSE: To assess the safety of delayed high dose intravenous (i.v.) sodium thiosulfate (STS) in a case series of 12 children with malignant brain tumors who were treated with intraarterial (i.a.) carboplatin in conjunction with blood-brain-barrier disruption (BBBD).
  • Analogous to results in adult patients, there was mild transient hypernatremia and a trend for improved protection from ototoxicity in children who received STS delayed to 4 hr post-treatment versus 2 hr.
  • [MeSH-minor] Auditory Threshold. Blood-Brain Barrier. Child. Child, Preschool. Drug Administration Schedule. Drug-Related Side Effects and Adverse Reactions. Ependymoma / drug therapy. Ependymoma / pathology. Female. Humans. Infant. Infusions, Intravenous. Male. Neuroectodermal Tumors, Primitive / drug therapy. Neuroectodermal Tumors, Primitive / pathology. Survival Analysis. Time Factors

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  • [CommentIn] Pediatr Blood Cancer. 2006 Aug;47(2):120-2 [16206212.001]
  • (PMID = 16086410.001).
  • [ISSN] 1545-5009
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Grant] United States / NINDS NIH HHS / NS / NS33618; United States / NINDS NIH HHS / NS / NS34608; United States / NINDS NIH HHS / NS / NS44687
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Chelating Agents; 0 / Thiosulfates; BG3F62OND5 / Carboplatin; HX1032V43M / sodium thiosulfate
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46. Koos B, Peetz-Dienhart S, Riesmeier B, Frühwald MC, Hasselblatt M: O(6)-methylguanine-DNA methyltransferase (MGMT) promoter methylation is significantly less frequent in ependymal tumours as compared to malignant astrocytic gliomas. Neuropathol Appl Neurobiol; 2010 Jun;36(4):356-8

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  • [Title] O(6)-methylguanine-DNA methyltransferase (MGMT) promoter methylation is significantly less frequent in ependymal tumours as compared to malignant astrocytic gliomas.
  • [MeSH-major] Astrocytoma / genetics. DNA Methylation. DNA Modification Methylases / genetics. DNA Repair Enzymes / genetics. Ependymoma / genetics. Promoter Regions, Genetic. Tumor Suppressor Proteins / genetics
  • [MeSH-minor] Adolescent. Adult. Age Factors. Aged. Aged, 80 and over. Child. Child, Preschool. Female. Humans. Infant. Male. Middle Aged. Young Adult

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  • (PMID = 20202118.001).
  • [ISSN] 1365-2990
  • [Journal-full-title] Neuropathology and applied neurobiology
  • [ISO-abbreviation] Neuropathol. Appl. Neurobiol.
  • [Language] eng
  • [Publication-type] Letter; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Tumor Suppressor Proteins; EC 2.1.1.- / DNA Modification Methylases; EC 2.1.1.63 / MGMT protein, human; EC 6.5.1.- / DNA Repair Enzymes
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47. Lopez-Gines C, Gil-Benso R, Faus C, Monleon D, Mata M, Morales JM, Cigudosa JC, Gonzalez-Darder J, Celda B, Cerda-Nicolas M: Metastasizing anaplastic ependymoma in an adult. Chromosomal imbalances, metabolic and gene expression profiles. Histopathology; 2009 Mar;54(4):500-4
MedlinePlus Health Information. consumer health - Brain Tumors.

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  • [Title] Metastasizing anaplastic ependymoma in an adult. Chromosomal imbalances, metabolic and gene expression profiles.
  • [MeSH-major] Brain Neoplasms / pathology. Ependymoma / pathology
  • [MeSH-minor] Adult. Anaplasia. Biomarkers, Tumor / metabolism. Chromosome Aberrations. Cyclin-Dependent Kinase Inhibitor p16 / genetics. Gene Expression Profiling. Genes, p53. Humans. In Situ Hybridization, Fluorescence. Magnetic Resonance Imaging. Male. Mutation. Oligonucleotide Array Sequence Analysis

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  • (PMID = 19309408.001).
  • [ISSN] 1365-2559
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Case Reports; Letter; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Cyclin-Dependent Kinase Inhibitor p16
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