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1. Doyle AJ, Pang AK, Miller MV, French JG: Magnetic resonance imaging of lipoma and atypical lipomatous tumour/well-differentiated liposarcoma: observer performance using T1-weighted and fluid-sensitive MRI. J Med Imaging Radiat Oncol; 2008 Feb;52(1):44-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Magnetic resonance imaging of lipoma and atypical lipomatous tumour/well-differentiated liposarcoma: observer performance using T1-weighted and fluid-sensitive MRI.
  • The aim of this study was to evaluate observer performance using T1-weighted spin-echo and fluid-sensitive MRI sequences in distinguishing between lipoma and atypical lipomatous tumour/well-differentiated liposarcoma (ALT/WDL).
  • [MeSH-major] Lipoma / diagnosis. Liposarcoma / diagnosis. Magnetic Resonance Imaging / methods. Magnetic Resonance Imaging / statistics & numerical data. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Observer Variation. Sensitivity and Specificity

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  • (PMID = 18373826.001).
  • [ISSN] 1754-9477
  • [Journal-full-title] Journal of medical imaging and radiation oncology
  • [ISO-abbreviation] J Med Imaging Radiat Oncol
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Australia
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2. Spark JI, Charalabidis P, Laws P, Seben R, Clayer M: Vascular reconstruction in lower limb musculoskeletal tumours. ANZ J Surg; 2009 Sep;79(9):619-23
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  • Four patients had a leiomyosarcoma, and one each of osteosarcoma, synovial chondrosarcoma, synovial sarcoma, liposarcoma and recurrent malignant peripheral nerve sheath tumour.
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Limb Salvage. Male. Middle Aged. Saphenous Vein / transplantation. Young Adult

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  • (PMID = 19895517.001).
  • [ISSN] 1445-2197
  • [Journal-full-title] ANZ journal of surgery
  • [ISO-abbreviation] ANZ J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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3. Guo H, Xiong Y, Nong L, Zhang S, Li T: [Reassessment of the pathological diagnosis in 33 cases of malignant fibrous histiocytoma]. Beijing Da Xue Xue Bao; 2008 Aug 18;40(4):374-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: Since malignant fibrous histiocytoma (MFH) may be taken as an undifferentiated pleomorphic sarcoma (UPS), this study was conducted to reassess 33 previously diagnosed MFH cases in the past 10 years based on the latest WHO concept.
  • Eleven cases (68.8%) variously expressed CD68 (KP1) and 7 cases (43.8%) expressed CD68 (PG-M1), which were much higher than leiomyosarcoma, malignant peripheral nerve sheath tumor and liposarcoma with significant difference.
  • CONCLUSION: MFH/UPS often show marked histological pleomorphism, and the diagnosis must be made by exclusion of other definitive sarcomas, especially myogenic and neurogenic sarcoma.
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Humans. Immunohistochemistry. Middle Aged

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  • (PMID = 18677383.001).
  • [ISSN] 1671-167X
  • [Journal-full-title] Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences
  • [ISO-abbreviation] Beijing Da Xue Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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4. Kilic M, Keskek M, Albayrak L, Ertan T, Gocmen E, Koc M: Liposarcoma of the thyroid gland: a case report. Acta Chir Belg; 2007 Jan-Feb;107(1):73-4
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  • [Title] Liposarcoma of the thyroid gland: a case report.
  • Primary liposarcoma of the thyroid gland is exceedingly rare with only five previous reports in the literature.
  • The histopathological examination revealed a well-differentiated thyroid liposarcoma.
  • [MeSH-major] Liposarcoma / pathology. Thyroid Neoplasms / pathology
  • [MeSH-minor] Adult. Humans. Male. Radiotherapy, Adjuvant. Thyroidectomy

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  • (PMID = 17405605.001).
  • [ISSN] 0001-5458
  • [Journal-full-title] Acta chirurgica Belgica
  • [ISO-abbreviation] Acta Chir. Belg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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5. Doglietto GB, Tortorelli AP, Papa V, Rosa F, Bossola M, Prete FP, Covino M, Pacelli F: Giant retroperitoneal sarcomas: a single institution experience. World J Surg; 2007 May;31(5):1047-54
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  • Advanced stage, incomplete gross surgical resection, higher tumor grade, non-liposarcoma histology and microscopic infiltration of margins were found to be significantly negative prognostic factors.
  • [MeSH-major] Retroperitoneal Neoplasms / surgery. Sarcoma / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Chi-Square Distribution. Female. Humans. Male. Middle Aged. Prognosis. Proportional Hazards Models. Survival Analysis. Treatment Outcome

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  • (PMID = 17345124.001).
  • [ISSN] 0364-2313
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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6. Dettrick AJ: Lipomatous hypertrophy of the interatrial septum: report of an unusual case. Histopathology; 2009 May;54(6):777-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Heart Atria / pathology. Heart Neoplasms / diagnosis. Humans. Hypertrophy. Lipoma / diagnosis. Liposarcoma / diagnosis

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  • (PMID = 19438758.001).
  • [ISSN] 1365-2559
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
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7. Leibl S, Moinfar F: Mammary NOS-type sarcoma with CD10 expression: a rare entity with features of myoepithelial differentiation. Am J Surg Pathol; 2006 Apr;30(4):450-6
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  • [Title] Mammary NOS-type sarcoma with CD10 expression: a rare entity with features of myoepithelial differentiation.
  • We present an extensive immunohistochemical analysis of 7 mammary sarcomas that did not fit into any specific soft tissue sarcoma category.
  • Other myoepithelial markers and steroid receptors were absent, except androgen receptors, which were expressed in one sarcoma.
  • The distinction of specific, histogenetically defined sarcoma entities (such as leiomyosarcoma, angiosarcoma, liposarcoma) from NOS-type sarcoma with CD10 expression is usually clear-cut because the former exhibit a characteristic histomorphology and immunoprofile.
  • The immunophenotype of NOS-type sarcomas with CD10 expression suggests that these neoplasms represent a mammary sarcoma variant with myoepithelial features.
  • [MeSH-major] Breast Neoplasms / pathology. Myoepithelioma / pathology. Neprilysin / metabolism. Sarcoma / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / metabolism. Carcinosarcoma / diagnosis. Cell Transformation, Neoplastic. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Middle Aged


8. Toro JR, Travis LB, Wu HJ, Zhu K, Fletcher CD, Devesa SS: Incidence patterns of soft tissue sarcomas, regardless of primary site, in the surveillance, epidemiology and end results program, 1978-2001: An analysis of 26,758 cases. Int J Cancer; 2006 Dec 15;119(12):2922-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Population Surveillance / methods. Sarcoma / epidemiology
  • [MeSH-minor] Adolescent. Adult. African Americans / statistics & numerical data. Age Factors. Aged. Aged, 80 and over. Dermatofibrosarcoma / epidemiology. European Continental Ancestry Group / statistics & numerical data. Female. Hemangiosarcoma / epidemiology. Histiocytoma, Benign Fibrous / epidemiology. Humans. Incidence. Liposarcoma / epidemiology. Male. Middle Aged. Rhabdomyosarcoma / epidemiology. Sex Factors. Skin Neoplasms / epidemiology. Soft Tissue Neoplasms / epidemiology. United States / epidemiology. Uterine Neoplasms / epidemiology

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  • [Copyright] Copyright 2006 Wiley-Liss, Inc.
  • (PMID = 17013893.001).
  • [ISSN] 0020-7136
  • [Journal-full-title] International journal of cancer
  • [ISO-abbreviation] Int. J. Cancer
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / /
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural
  • [Publication-country] United States
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9. Crapanzano JP: Fine-needle aspiration of renal angiomyolipoma: cytological findings and diagnostic pitfalls in a series of five cases. Diagn Cytopathol; 2005 Jan;32(1):53-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Diagnosis of renal angiomyolipoma (AML) by fine-needle aspiration (FNA) may be difficult because cytological and radiological findings sometimes overlap with renal cell carcinoma (RCC) and liposarcoma.
  • In FNA, bland chromatin and inconspicuous nucleoli distinguish renal AML from RCC and liposarcoma.
  • Cellular atypia in conjunction with overlapping radiological findings with RCC and liposarcoma are potential diagnostic pitfalls.
  • [MeSH-minor] Adenoma, Oxyphilic / diagnosis. Adult. Aged. Carcinoma, Renal Cell / diagnosis. Diagnosis, Differential. Epithelioid Cells / pathology. Female. Humans. Liposarcoma / diagnosis. Male. Middle Aged. Retroperitoneal Neoplasms / diagnosis. Stromal Cells / pathology

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  • [Copyright] (c) 2005 Wiley-Liss, Inc.
  • (PMID = 15584043.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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10. Sievers S, Fritzsch C, Lehnhardt M, Zahn S, Kutzner N, Kuhnen C, Müller O: Hypermethylation of the APC promoter but lack of APC mutations in myxoid/round-cell liposarcoma. Int J Cancer; 2006 Nov 15;119(10):2347-52
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  • [Title] Hypermethylation of the APC promoter but lack of APC mutations in myxoid/round-cell liposarcoma.
  • Although APC has been shown to be genetically or epigenetically inactivated in a variety of carcinomas, little is known about its role in sarcoma.
  • Liposarcomas (LPSs) are the second most common soft tissue sarcoma in adults.
  • Sequencing of the mutation cluster region, the protein truncation test and a loss of heterozygosity (LOH) analysis did not reveal any genetic alterations of the APC gene in all of the liposarcoma samples.
  • However, the impact of APC methylation on liposarcoma development is quite likely not mediated through WNT signalling.
  • [MeSH-major] DNA Methylation. Gene Silencing. Genes, APC. Liposarcoma, Myxoid / genetics. Liposarcoma, Myxoid / pathology. Mutation
  • [MeSH-minor] Adult. Aged. Down-Regulation. Enzyme-Linked Immunosorbent Assay. Epigenesis, Genetic. Female. Humans. Loss of Heterozygosity. Male. Middle Aged. Promoter Regions, Genetic. Reverse Transcriptase Polymerase Chain Reaction. Sequence Analysis, DNA. beta Catenin / analysis

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  • (PMID = 16858687.001).
  • [ISSN] 0020-7136
  • [Journal-full-title] International journal of cancer
  • [ISO-abbreviation] Int. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CTNNB1 protein, human; 0 / beta Catenin
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11. Zhang L, Alsabeh R, Mecucci C, La Starza R, Gorello P, Lee S, Lill M, Schreck R: Rare t(1;11)(q23;p15) in therapy-related myelodysplastic syndrome evolving into acute myelomonocytic leukemia: a case report and review of the literature. Cancer Genet Cytogenet; 2007 Oct 1;178(1):42-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report on an additional patient with t(1;11) who presented with myelodysplastic syndrome (MDS) subsequent to treatment for a pleomorphic liposarcoma.
  • [MeSH-minor] Adult. Aged. Disease Progression. Female. Humans. In Situ Hybridization, Fluorescence. Karyotyping. Male. Middle Aged. Neutrophils / metabolism


12. Liu L, Wei X, Pan T: A giant primary myxoid liposarcoma of the posterior mediastinum. Eur J Cardiothorac Surg; 2010 Apr;37(4):958
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A giant primary myxoid liposarcoma of the posterior mediastinum.
  • [MeSH-major] Liposarcoma, Myxoid / radiography. Mediastinal Neoplasms / radiography
  • [MeSH-minor] Adult. Humans. Male. Tomography, X-Ray Computed

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  • (PMID = 20185322.001).
  • [ISSN] 1873-734X
  • [Journal-full-title] European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • [ISO-abbreviation] Eur J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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13. Yu RS, Chen Y, Jiang B, Wang LH, Xu XF: Primary hepatic sarcomas: CT findings. Eur Radiol; 2008 Oct;18(10):2196-205
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  • In this pictorial review, we summarized computed tomography (CT) findings of some relatively common types of hepatic sarcomas, including angiosarcoma, epithelioid hemangioendothelioma (EHE), liposarcoma, undifferentiated embryonal sarcoma (UES), leiomyosarcoma, malignant fibrous histiocytoma (MFH), and carcinosarcoma (including cystadenocarcinosarcoma).
  • [MeSH-major] Liver / diagnostic imaging. Liver Neoplasms / diagnostic imaging. Sarcoma / diagnostic imaging. Tomography, X-Ray Computed / methods
  • [MeSH-minor] Adult. Aged. Child. Female. Humans. Male. Middle Aged

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  • (PMID = 18463872.001).
  • [ISSN] 0938-7994
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 53
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14. Powitzky R, Powitzky ES, Garcia R: Liposarcoma of the larynx. Ann Otol Rhinol Laryngol; 2007 Jun;116(6):418-24
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Liposarcoma of the larynx.
  • OBJECTIVES: The objective was to review the presentation, diagnosis, treatment, and prognosis of patients with laryngeal liposarcoma (LLS).
  • [MeSH-major] Laryngeal Neoplasms / pathology. Liposarcoma / pathology
  • [MeSH-minor] Adult. Aged. Biopsy. Female. Humans. Laryngoscopy / methods. Male. Middle Aged

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  • (PMID = 17672243.001).
  • [ISSN] 0003-4894
  • [Journal-full-title] The Annals of otology, rhinology, and laryngology
  • [ISO-abbreviation] Ann. Otol. Rhinol. Laryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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15. Chute DJ, Shutter J, Mills SE: Pathology quiz case 2. Pleomorphic liposarcoma (PLS) of the retrotonsillar fossa. Arch Otolaryngol Head Neck Surg; 2007 Mar;133(3):303, 305
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  • [Title] Pathology quiz case 2. Pleomorphic liposarcoma (PLS) of the retrotonsillar fossa.
  • [MeSH-major] Liposarcoma / pathology. Tonsillar Neoplasms / pathology
  • [MeSH-minor] Adult. Female. Humans. Tonsillitis / etiology

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  • (PMID = 17372093.001).
  • [ISSN] 0886-4470
  • [Journal-full-title] Archives of otolaryngology--head & neck surgery
  • [ISO-abbreviation] Arch. Otolaryngol. Head Neck Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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16. Demetri GD, Chawla SP, von Mehren M, Ritch P, Baker LH, Blay JY, Hande KR, Keohan ML, Samuels BL, Schuetze S, Lebedinsky C, Elsayed YA, Izquierdo MA, Gómez J, Park YC, Le Cesne A: Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: results of a randomized phase II study of two different schedules. J Clin Oncol; 2009 Sep 1;27(25):4188-96
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  • [Title] Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: results of a randomized phase II study of two different schedules.
  • PURPOSE: To evaluate the safety and efficacy of trabectedin in a phase II, open-label, multicenter, randomized study in adult patients with unresectable/metastatic liposarcoma or leiomyosarcoma after failure of prior conventional chemotherapy including anthracyclines and ifosfamide.
  • [MeSH-major] Anthracyclines / therapeutic use. Antibiotics, Antineoplastic / therapeutic use. Antineoplastic Agents, Alkylating / administration & dosage. Antineoplastic Agents, Alkylating / therapeutic use. Dioxoles / administration & dosage. Drug Resistance, Neoplasm. Ifosfamide / therapeutic use. Leiomyosarcoma / drug therapy. Liposarcoma / drug therapy. Tetrahydroisoquinolines / administration & dosage
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Australia. Disease-Free Survival. Drug Administration Schedule. Europe. Female. Humans. Infusions, Intravenous. Kaplan-Meier Estimate. Male. Middle Aged. Neoplasm Staging. North America. Proportional Hazards Models. Risk Assessment. Time Factors. Treatment Failure. Young Adult


17. de Saint Aubain Somerhausen N, Coindre JM, Debiec-Rychter M, Delplace J, Sciot R: Lipoblastoma in adolescents and young adults: report of six cases with FISH analysis. Histopathology; 2008 Feb;52(3):294-8
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  • Histologically, there is some morphological overlap with atypical lipomatous tumour and myxoid liposarcoma and the age at presentation is often regarded as a major diagnostic criterion.
  • [MeSH-minor] Adipocytes / pathology. Adolescent. Adult. Chromosome Aberrations. Disease-Free Survival. Female. Humans. Male. Neoplasm Recurrence, Local

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  • (PMID = 18269579.001).
  • [ISSN] 1365-2559
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DNA, Neoplasm
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18. Lucas DR, Shukla A, Thomas DG, Patel RM, Kubat AJ, McHugh JB: Dedifferentiated liposarcoma with inflammatory myofibroblastic tumor-like features. Am J Surg Pathol; 2010 Jun;34(6):844-51
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  • [Title] Dedifferentiated liposarcoma with inflammatory myofibroblastic tumor-like features.
  • The dedifferentiated component of dedifferentiated liposarcoma shows wide histologic variation including tumors with heterologous differentiation.
  • Myofibroblastic differentiation has been recognized in dedifferentiated liposarcoma.
  • We report the clinicopathologic, immunohistochemical, and molecular finding in 6 cases of dedifferentiated liposarcoma with inflammatory myofibroblastic tumor-like features treated at our institution.
  • In 4 tumors the inflammatory myofibroblastic tumor-like areas were diffuse, whereas in 2 they were combined with noninflammatory myofibroblastic tumor-like high-grade sarcoma.
  • Dedifferentiated liposarcoma can have prominent inflammatory myofibroblastic tumor-like features, a finding that further expands its histologic spectrum.
  • Awareness of this finding can prevent one from misdiagnosing dedifferentiated liposarcoma as inflammatory myofibroblastic tumor, a much less aggressive neoplasm.
  • [MeSH-major] Liposarcoma / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Female. Humans. Immunohistochemistry. Male. Middle Aged

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  • (PMID = 20431481.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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19. Malleo G, Crippa S, Partelli S, Capelli P, Salvia R, Bassi C: Pleomorphic liposarcoma of the axilla metastatic to the pancreas. Dig Surg; 2009;26(3):262-3
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  • [Title] Pleomorphic liposarcoma of the axilla metastatic to the pancreas.
  • [MeSH-major] Liposarcoma / secondary. Neoplasms, Second Primary / secondary. Pancreatic Neoplasms / secondary
  • [MeSH-minor] Adult. Axilla. Diagnosis, Differential. Follow-Up Studies. Humans. Male. Neoplasms, Germ Cell and Embryonal / pathology. Neoplasms, Germ Cell and Embryonal / therapy. Testicular Neoplasms / pathology. Testicular Neoplasms / therapy. Treatment Outcome

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  • (PMID = 19590203.001).
  • [ISSN] 1421-9883
  • [Journal-full-title] Digestive surgery
  • [ISO-abbreviation] Dig Surg
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Switzerland
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20. Wang JG, Wei ZM, Liu H, Li YJ: Primary pleomorphic liposarcoma of pericardium. Interact Cardiovasc Thorac Surg; 2010 Sep;11(3):325-7
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  • [Title] Primary pleomorphic liposarcoma of pericardium.
  • The tumor underwent completely resection and histopathological analysis revealed the tumor to be a pleomorphic liposarcoma, which was composed predominantly of epithelioid cells.
  • The rare incidence of the liposarcoma of the pericardium can easily lead to a misdiagnosis clinically, and the final diagnosis here was made histopathologically.
  • [MeSH-major] Heart Neoplasms / diagnosis. Liposarcoma / diagnosis
  • [MeSH-minor] Adult. Biopsy. Cardiac Surgical Procedures. Diagnostic Errors. Humans. Immunohistochemistry. Male. Neoplasm Recurrence, Local / surgery. Pericardium / pathology. Pericardium / surgery. Reoperation. Teratoma / diagnosis. Tomography, X-Ray Computed. Treatment Outcome

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  • [CommentIn] Interact Cardiovasc Thorac Surg. 2010 Sep;11(3):327 [20719913.001]
  • (PMID = 20591887.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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21. Grosso F, Jones RL, Demetri GD, Judson IR, Blay JY, Le Cesne A, Sanfilippo R, Casieri P, Collini P, Dileo P, Spreafico C, Stacchiotti S, Tamborini E, Tercero JC, Jimeno J, D'Incalci M, Gronchi A, Fletcher JA, Pilotti S, Casali PG: Efficacy of trabectedin (ecteinascidin-743) in advanced pretreated myxoid liposarcomas: a retrospective study. Lancet Oncol; 2007 Jul;8(7):595-602
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  • BACKGROUND: Previous studies have suggested that trabectedin (ecteinascidin-743) could have antitumour activity in soft-tissue sarcoma.
  • We aimed to study the usefulness of trabectedin in the treatment of patients with myxoid liposarcomas, a subtype of liposarcoma that is associated with specific chromosomal translocations t(12;16)(q13;p11) or t(12;22)(q13;q12) that result in the formation of DDIT3-FUS or DDIT3-EWSR1 fusion proteins.
  • METHODS: 51 patients with advanced pretreated myxoid liposarcoma who started treatment with trabectedin between April 4, 2001, and Sept 18, 2006 at five institutions in a compassionate-use programme were analysed retrospectively.
  • INTERPRETATION: Trabectedin was associated with antitumour activity in this series of patients with myxoid liposarcoma.
  • This analysis has resulted in the initiation of two prospective studies to assess the role of trabectedin in the treatment of patients with myxoid liposarcoma in preoperative and metastatic settings.
  • Furthermore, the selective mechanism of action for trabectedin in this translocation-related sarcoma is being studied.
  • [MeSH-major] Antineoplastic Agents, Alkylating / therapeutic use. Dioxoles / therapeutic use. Liposarcoma, Myxoid / drug therapy. Tetrahydroisoquinolines / therapeutic use
  • [MeSH-minor] Adult. Disease-Free Survival. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Oncogene Proteins, Fusion / genetics. Oncogene Proteins, Fusion / metabolism. Retrospective Studies. Tomography, X-Ray Computed

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  • [CommentIn] Lancet Oncol. 2007 Jul;8(7):565-7 [17613417.001]
  • (PMID = 17586092.001).
  • [ISSN] 1470-2045
  • [Journal-full-title] The Lancet. Oncology
  • [ISO-abbreviation] Lancet Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Alkylating; 0 / Dioxoles; 0 / Oncogene Proteins, Fusion; 0 / Tetrahydroisoquinolines; 114899-77-3 / trabectedin
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22. Chung L, Lau SK, Jiang Z, Loera S, Bedel V, Ji J, Weiss LM, Chu PG: Overlapping features between dedifferentiated liposarcoma and undifferentiated high-grade pleomorphic sarcoma. Am J Surg Pathol; 2009 Nov;33(11):1594-600
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  • [Title] Overlapping features between dedifferentiated liposarcoma and undifferentiated high-grade pleomorphic sarcoma.
  • Dedifferentiated liposarcoma (DDL), occurring in up to 10% of well differentiated liposarcoma cases, has similar histologic features to that of undifferentiated high-grade pleomorphic sarcoma (UHGPS); the former develops in a background of atypical lipomatous tumors/well differentiated liposarcoma, whereas the latter shows no specific line of differentiation.
  • [MeSH-major] Liposarcoma / diagnosis. Retroperitoneal Neoplasms / diagnosis. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Adipocytes / metabolism. Adipocytes / pathology. Adolescent. Adult. Aged. Biomarkers, Tumor / metabolism. Cell Nucleus / metabolism. Cell Nucleus / pathology. Cyclin-Dependent Kinase 4 / metabolism. Diagnosis, Differential. Female. Humans. Immunohistochemistry. In Situ Hybridization, Fluorescence. Liposarcoma, Myxoid / diagnosis. Liposarcoma, Myxoid / metabolism. Liposarcoma, Myxoid / surgery. Male. Middle Aged. PPAR gamma / metabolism. Proto-Oncogene Proteins c-mdm2 / metabolism. Thigh. Young Adult

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  • (PMID = 19574885.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / PPAR gamma; EC 2.7.11.22 / CDK4 protein, human; EC 2.7.11.22 / Cyclin-Dependent Kinase 4; EC 6.3.2.19 / MDM2 protein, human; EC 6.3.2.19 / Proto-Oncogene Proteins c-mdm2
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23. Cecchetto G, Alaggio R, Dall'Igna P, Bisogno G, Ferrari A, Gigante C, Casanova M, Sotti G, Zanetti I, Carli M: Localized unresectable non-rhabdo soft tissue sarcomas of the extremities in pediatric age: results from the Italian studies. Cancer; 2005 Nov 1;104(9):2006-12
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  • Chemosensitive (CTs) sarcomas, 21: synovial sarcoma, 11; extraosseous Ewing sarcomas, 5; primitive peripheral neuroectodermic tumors, 5.
  • Nonchemosensitive (CTns) sarcomas, 31: fibrosarcoma, 11; malignant peripheral nerve sheet tumors, 10; liposarcoma, 2; hemangiopericitoma adult type, 2; epithelioid sarcoma, 2; and alveolar soft part sarcoma, leiomyosarcoma, clear cell sarcoma, and sarcoma NOS, each 1.
  • [MeSH-major] Extremities. Sarcoma / diagnosis

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  • [Copyright] (c) 2005 American Cancer Society.
  • (PMID = 16161038.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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24. Tayal S, Classen E, Bemis L, Robinson WA: C-kit expression in dedifferentiated and well-differentiated liposarcomas; immunohistochemistry and genetic analysis. Anticancer Res; 2005 May-Jun;25(3B):2215-20
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  • [MeSH-major] Liposarcoma / enzymology. Liposarcoma / pathology. Proto-Oncogene Proteins c-kit / biosynthesis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Cell Differentiation / physiology. Exons. Female. Humans. Immunohistochemistry. Male. Middle Aged. Polymerase Chain Reaction. Retroperitoneal Neoplasms / enzymology. Retroperitoneal Neoplasms / genetics. Retroperitoneal Neoplasms / pathology. Sequence Analysis, DNA

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  • (PMID = 16158966.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA046934-17
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] Greece
  • [Chemical-registry-number] EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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25. Ibe T, Otani Y, Shimizu K, Nakano T, Sano T, Morishita Y: Pulmonary pleomorphic liposarcoma. Jpn J Thorac Cardiovasc Surg; 2005 Aug;53(8):443-7
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  • [Title] Pulmonary pleomorphic liposarcoma.
  • Pulmonary liposarcoma is extremely rare with 6 cases previously reported in the English literature.
  • The following is a report of a 36-year-old man with pulmonary liposarcoma.
  • Because of the fatty tissue component in the tumor on the chest computed tomography, and the appearance as an extrapulmonary mass, preoperative diagnosis was posterior mediastinal liposarcoma.
  • The pathological diagnosis was pleomorphic liposarcoma originated from the lung.
  • [MeSH-major] Liposarcoma / diagnosis. Lung Neoplasms / diagnosis. Neoplasm Recurrence, Local
  • [MeSH-minor] Adult. Fatal Outcome. Humans. Magnetic Resonance Imaging. Male. Pneumonectomy. Tomography, X-Ray Computed

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  • [Cites] Lung Cancer. 1997 Jul;17(2-3):271-5 [9237162.001]
  • [Cites] Virchows Arch Pathol Anat Physiol Klin Med. 1962;335:367-88 [13890373.001]
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  • (PMID = 16164258.001).
  • [ISSN] 1344-4964
  • [Journal-full-title] The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi
  • [ISO-abbreviation] Jpn. J. Thorac. Cardiovasc. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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26. Jaovisidha S, Suvikapakornkul Y, Woratanarat P, Subhadrabandhu T, Nartthanarung A, Siriwongpairat P: MR imaging of fat-containing tumours: the distinction between lipoma and liposarcoma. Singapore Med J; 2010 May;51(5):418-23
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  • [Title] MR imaging of fat-containing tumours: the distinction between lipoma and liposarcoma.
  • INTRODUCTION: This study aimed to retrospectively review the magnetic resonance (MR) imaging features of the lipomatous tumour in order to differentiate between lipoma and liposarcoma.
  • METHODS: The MR images of 38 patients (24 female and 14 male with a mean age 48 years) in a consecutive five-year period, who had histologically verified lipoma (n is 29) and liposarcoma (n is 9), were retrospectively reviewed.
  • RESULTS: A partially ill-defined margin, neurovascular involvement, enhancing thick/nodular septum and a partially bright signal intensity on T1W images were statistically significant MR imaging features that favoured a diagnosis of liposarcoma (p-value is less than 0.0001).
  • Male gender, an internal cystic change and surrounding soft tissue oedema increased the risk of liposarcoma approximately 2.8, 3.5 and 3.5 times, respectively, compared with the reference group (lipoma), but this was not a statistically significant finding.
  • Thick/nodular septum was significantly associated with liposarcoma compared with lipoma (odds ratio 69.3, 95 percent confidence interval 5.2-3184.8, p-value is less than 0.0001).
  • CONCLUSION: Statistically significant MR imaging features that favour a diagnosis of liposarcoma included a partially ill-defined margin, neurovascular involvement, enhancing thick/nodular septum, and a partially bright signal intensity on T1W images.
  • The most statistically significant predictor of liposarcoma was thick/nodular septum.
  • [MeSH-major] Lipoma / diagnosis. Liposarcoma / diagnosis. Magnetic Resonance Imaging. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Adult. Confidence Intervals. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Muscle Neoplasms / diagnosis. Muscle Neoplasms / pathology. Odds Ratio. Retrospective Studies. Risk Factors

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  • (PMID = 20593147.001).
  • [ISSN] 0037-5675
  • [Journal-full-title] Singapore medical journal
  • [ISO-abbreviation] Singapore Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Singapore
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27. Neuhaus SJ, Barry P, Clark MA, Hayes AJ, Fisher C, Thomas JM: Surgical management of primary and recurrent retroperitoneal liposarcoma. Br J Surg; 2005 Feb;92(2):246-52
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  • [Title] Surgical management of primary and recurrent retroperitoneal liposarcoma.
  • BACKGROUND: Surgery plays a dominant role in the initial and subsequent treatment of retroperitoneal liposarcoma (RPLS).
  • [MeSH-major] Liposarcoma / surgery. Neoplasm Recurrence, Local / surgery. Retroperitoneal Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Disease-Free Survival. Female. Humans. Length of Stay. Male. Middle Aged. Palliative Care / methods. Prognosis. Prospective Studies. Tomography, X-Ray Computed / methods. Treatment Outcome

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  • (PMID = 15505870.001).
  • [ISSN] 0007-1323
  • [Journal-full-title] The British journal of surgery
  • [ISO-abbreviation] Br J Surg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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28. Marulli G, Rea F, Feltracco P, Calabrese F, Giacometti C, Rizzardi G, Vincenzo L, Sartori F: Successful resection of a giant primary liposarcoma of the posterior mediastinum. J Thorac Oncol; 2007 May;2(5):453-5
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  • [Title] Successful resection of a giant primary liposarcoma of the posterior mediastinum.
  • We present a case involving a successful radical resection of a large myxoid liposarcoma and its recurrence, both located in the posterior mediastinum.
  • [MeSH-major] Liposarcoma / diagnosis. Mediastinal Neoplasms / diagnosis
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. Neoplasm Recurrence, Local. Reoperation. Thoracotomy. Tomography, X-Ray Computed

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  • (PMID = 17473663.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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29. Alford SH, Vrana MS, Waite L, Heim-Hall J, Sylvia VL, Williams RP: Matrix metalloproteinase expression in high grade soft tissue sarcomas. Oncol Rep; 2007 Dec;18(6):1529-36
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  • Among the more common aggressive adult soft tissue sarcomas are malignant fibrous histiocytoma, synovial sarcoma and liposarcoma.
  • The objectives of this study are to determine the presence and relative quantity of matrix metalloproteinases (MMPs) -1, -2, -8, -9, and -13; extracellular matrix metalloproteinase inducer (EMMPRIN); and tissue inhibitors of matrix metalloproteinases (TIMP)-1 and -2 in high grade soft tissue sarcoma tumor specimens using real-time PCR.
  • [MeSH-major] Sarcoma / enzymology
  • [MeSH-minor] Biopsy. Humans. Liposarcoma / enzymology. Liposarcoma / mortality. Retrospective Studies. Sarcoma, Synovial / enzymology. Sarcoma, Synovial / mortality. Survival Analysis. Time Factors. Tissue Inhibitor of Metalloproteinase-1 / analysis. Tissue Inhibitor of Metalloproteinase-2 / analysis

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  • (PMID = 17982640.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Tissue Inhibitor of Metalloproteinase-1; 127497-59-0 / Tissue Inhibitor of Metalloproteinase-2
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30. ten Heuvel SE, Hoekstra HJ, van Ginkel RJ, Bastiaannet E, Suurmeijer AJ: Clinicopathologic prognostic factors in myxoid liposarcoma: a retrospective study of 49 patients with long-term follow-up. Ann Surg Oncol; 2007 Jan;14(1):222-9
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  • [Title] Clinicopathologic prognostic factors in myxoid liposarcoma: a retrospective study of 49 patients with long-term follow-up.
  • BACKGROUND: The main goal of this retrospective study was to investigate prognostic factors influencing the survival of myxoid liposarcoma (MLS) with emphasis on the role of transitional areas (TLS) and round cell morphology (RCLS).
  • [MeSH-major] Liposarcoma, Myxoid / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Prognosis. Survival Rate

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  • (PMID = 17058128.001).
  • [ISSN] 1068-9265
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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31. Raghavan R, Raghuram P, Parekh PV, Kurien JM: Posterior mediastinal liposarcoma simulating a lung mass: an unusual case report. Cancer Imaging; 2007;7:141-4
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  • [Title] Posterior mediastinal liposarcoma simulating a lung mass: an unusual case report.
  • [MeSH-major] Liposarcoma / radiography. Lung Neoplasms / diagnosis. Mediastinal Neoplasms / radiography
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Male. Treatment Outcome

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  • (PMID = 17964955.001).
  • [ISSN] 1470-7330
  • [Journal-full-title] Cancer imaging : the official publication of the International Cancer Imaging Society
  • [ISO-abbreviation] Cancer Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2072088
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32. Thanakit V, Nelson SD, Udomsawaengsup S: Round cell liposarcoma of scrotum with indolent course in young adult. J Med Assoc Thai; 2005 Sep;88(9):1302-7
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  • [Title] Round cell liposarcoma of scrotum with indolent course in young adult.
  • Myxoid/Round cell liposarcoma accounts for one-half of all liposarcomas and occurs as the second most common subtype.
  • Both myxoid and round cell types share clinical, histological features and are accepted to represent a spectrum of lesions ranging from pure myxoid to near completely round cell liposarcoma.
  • Round cell liposarcoma is highly metastatic and is classified as high grade and poorly differentiated myxoid sarcoma.
  • Typical non-round cell myxoid liposarcoma is less metastatic and has more favorable prognosis.
  • Liposarcoma represents approximately 20% of malignant extratesticular neoplasms, with the well differentiated subtype being the most common.
  • Myxoid/round cell liposarcoma and round cell liposarcoma are rarely encounter in extratesticular soft tissue.
  • We reported a rare case of round cell liposarcoma (high grade myxoid liposarcoma) of extratesticular tissue.
  • To our knowledge, this is the first case of a large size (> 5cm) round cell liposarcoma arising from soft tissue within the scrotal sac of young adult with indolent course.
  • [MeSH-major] Carcinoma, Small Cell / pathology. Liposarcoma, Myxoid / pathology. Testicular Neoplasms / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Male. Prognosis. Scrotum / pathology. Testicular Hydrocele / pathology

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  • (PMID = 16536120.001).
  • [ISSN] 0125-2208
  • [Journal-full-title] Journal of the Medical Association of Thailand = Chotmaihet thangphaet
  • [ISO-abbreviation] J Med Assoc Thai
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Thailand
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33. Colin P, Lagacé R, Caillaud JM, Sastre-Garau X, Klijanienko J: Fine-needle aspiration in myxofibrosarcoma: experience of Institut Curie. Diagn Cytopathol; 2010 May;38(5):343-6
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  • Four cases were classified malignant myxoid sarcoma (1 primary and 3 recurrences), whereas three cases (2 primary and 1 recurrence) were false-negative.The smears were cell-rich in 12 cases and cell-poor in two cases.
  • Entities such as myxoid MFH, myxoid liposarcoma (MLP), myxoid DFSP, and myxoma should be considered in the differential diagnosis.
  • [MeSH-major] Academies and Institutes. Fibroma / pathology. Sarcoma / pathology
  • [MeSH-minor] Adult. Aged. Biopsy, Fine-Needle. Female. Humans. Male. Middle Aged

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  • (PMID = 19899126.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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34. Smith MA, Kluck E, Jagannath S, Yang SC: Giant multi-polypoid liposarcoma of the esophagus: an atypical presentation. Ann Thorac Surg; 2010 Feb;89(2):610-2
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  • [Title] Giant multi-polypoid liposarcoma of the esophagus: an atypical presentation.
  • We present a giant, well-differentiated liposarcoma of the esophagus with multiple pedunculated polypoid-like growths, which made it radiographically and pathologically noncharacteristic.
  • [MeSH-major] Deglutition Disorders / etiology. Esophageal Neoplasms / diagnosis. Esophageal Neoplasms / surgery. Hoarseness / etiology. Liposarcoma / diagnosis. Liposarcoma / surgery. Neoplasm, Residual / diagnosis. Neoplasm, Residual / surgery. Polyps / diagnosis. Polyps / surgery. Postoperative Complications / diagnosis. Postoperative Complications / surgery. Respiratory Sounds / etiology
  • [MeSH-minor] Adult. Endosonography. Esophagectomy. Esophagoscopy. Esophagus / pathology. Humans. Male. Reoperation. Tomography, X-Ray Computed

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  • [Copyright] 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20103356.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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35. Goldsmith P, Papagiannopoulos K: Pleural myxoid liposarcoma: features of 2 cases and associated literature review. J Cardiothorac Surg; 2007;2:48
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  • [Title] Pleural myxoid liposarcoma: features of 2 cases and associated literature review.
  • Primary pleural myxoid liposarcoma is a rare entity and no agreed treatment options have been formulated once diagnosis has been made.
  • [MeSH-major] Liposarcoma, Myxoid / diagnosis. Liposarcoma, Myxoid / surgery. Pleural Neoplasms / diagnosis. Pleural Neoplasms / surgery
  • [MeSH-minor] Adult. Aged, 80 and over. Combined Modality Therapy. Fatal Outcome. Female. Humans. Male. Thoracotomy. Tomography, X-Ray Computed

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36. Adigun IA, Rahman GA, Buhari MO, Ogundipe KO, Omotayo JA: Soft-tissue sarcoma in black Africans: pattern, distribution and management dilemma. J Natl Med Assoc; 2007 Jan;99(1):88-93
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  • [Title] Soft-tissue sarcoma in black Africans: pattern, distribution and management dilemma.
  • Fibrosarcoma was the commonest STS, followed by malignant fibrous histocytoma, liposarcoma and rhabdomyosarcoma.
  • Fibrosarcoma, malignant fibrous histocytoma and liposarcoma are more common in the extremities while leiomyosarcoma is more common in the intra-abdominal region.
  • [MeSH-major] Sarcoma. Soft Tissue Neoplasms
  • [MeSH-minor] Adolescent. Adult. African Continental Ancestry Group. Aged. Child. Child, Preschool. Humans. Infant. Infant, Newborn. Middle Aged. Retrospective Studies

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37. Gimble JM, Katz AJ, Bunnell BA: Adipose-derived stem cells for regenerative medicine. Circ Res; 2007 May 11;100(9):1249-60
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  • Adipose tissue represents an abundant and accessible source of adult stem cells with the ability to differentiate along multiple lineage pathways.
  • [MeSH-major] Adipose Tissue / cytology. Adult Stem Cells / cytology. Cell Differentiation. Tissue Engineering
  • [MeSH-minor] Adipogenesis. Cell Lineage. Cell Proliferation. Cell Separation / methods. Humans. Immunophenotyping. Lipoma / pathology. Liposarcoma / pathology. Obesity / pathology. Proteome. Terminology as Topic

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  • (PMID = 17495232.001).
  • [ISSN] 1524-4571
  • [Journal-full-title] Circulation research
  • [ISO-abbreviation] Circ. Res.
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / P30 DK072476; United States / NCRR NIH HHS / RR / P51 RR000164; United States / NCRR NIH HHS / RR / RR00164
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Proteome
  • [Number-of-references] 142
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38. Fellah L, Debehogne M, El Mouedden J, Akle N, Berlière M, Galant C, Leconte I: [Breast liposarcoma]. JBR-BTR; 2010 Nov-Dec;93(6):299-301
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  • [Title] [Breast liposarcoma].
  • [Transliterated title] Breast liposarcoma.
  • Liposarcoma of the breast constitutes 1% of all malignant breast tumors.
  • [MeSH-major] Breast Neoplasms / pathology. Liposarcoma / pathology
  • [MeSH-minor] Adult. Biopsy, Needle. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Mammography. Ultrasonography, Mammary

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  • (PMID = 21384685.001).
  • [ISSN] 0302-7430
  • [Journal-full-title] JBR-BTR : organe de la Société royale belge de radiologie (SRBR) = orgaan van de Koninklijke Belgische Vereniging voor Radiologie (KBVR)
  • [ISO-abbreviation] JBR-BTR
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Belgium
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39. Alyas F, Lee J, Ahmed M, Connell D, Saifuddin A: Prevalence and diagnostic significance of fluid-fluid levels in soft-tissue neoplasms. Clin Radiol; 2007 Aug;62(8):769-74; discussion 775
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  • One of the 24 (4.1%) was non-neoplastic (one ganglion), 12 (50.0%) were benign neoplasms (nine haemangiomas, two schwannomas, one hamartoma) and 11 (45.9%) were malignant neoplasms (one leiomyosarcoma, one liposarcoma, one malignant fibrous histocytoma, one mxyofibrosarcoma, two primitive neuroectodermal tumours, two synovial sarcomas, one spindle cell sarcoma, and two sarcomas not otherwise specified).
  • [MeSH-minor] Adult. Biopsy. Exudates and Transudates. Female. Humans. Image Enhancement. Magnetic Resonance Imaging / methods. Male. Middle Aged. Retrospective Studies

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  • [CommentIn] Clin Radiol. 2008 May;63(5):610; author reply 610 [18374727.001]
  • (PMID = 17604765.001).
  • [ISSN] 0009-9260
  • [Journal-full-title] Clinical radiology
  • [ISO-abbreviation] Clin Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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40. Buyukhatipoglu H, Sevinc A, Camci C, Buyukberber S, Sari I: A case representing coexistence of acute myeloblastic leukemia and dedifferentiated liposarcoma: the possible role of chemotherapy in triggering dedifferentiation. Clin Lab Haematol; 2006 Oct;28(5):343-6
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  • [Title] A case representing coexistence of acute myeloblastic leukemia and dedifferentiated liposarcoma: the possible role of chemotherapy in triggering dedifferentiation.
  • Dedifferentiated and well-differentiated liposarcomas are the two pathological subtypes of liposarcoma, based on the WHO classification.
  • Transition from well-differentiated to dedifferentiated liposarcoma is a well-recognized phenomenon.
  • To date, the coexistence of AML and liposarcoma has not been reported in the literature.
  • In this paper, we report on a case of coexistence of AML and liposarcoma, and on the unusual behavior of a well-differentiated tumor after dedifferentiation occurs.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / adverse effects. Leukemia, Myeloid, Acute / drug therapy. Liposarcoma / chemically induced
  • [MeSH-minor] Abdominal Neoplasms / pathology. Adult. Bone Neoplasms / secondary. Female. Humans

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  • (PMID = 16999727.001).
  • [ISSN] 0141-9854
  • [Journal-full-title] Clinical and laboratory haematology
  • [ISO-abbreviation] Clin Lab Haematol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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41. Lee TJ, Collins J: MR imaging evaluation of disorders of the chest wall. Magn Reson Imaging Clin N Am; 2008 May;16(2):355-79, x
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  • Among the diseases they discuss are diseases of the soft tissue including lipoma, hibernoma, liposarcoma, hemangioma, and lymphoma.
  • In addition, they discuss such malignant osseous tumors as osteosarcoma and Ewing's sarcoma.
  • [MeSH-minor] Adult. Female. Humans. Male. Middle Aged

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  • (PMID = 18474337.001).
  • [ISSN] 1064-9689
  • [Journal-full-title] Magnetic resonance imaging clinics of North America
  • [ISO-abbreviation] Magn Reson Imaging Clin N Am
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 137
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42. Nikolaidis P, Silverman SG, Cibas ES, Vansonnenberg E, Rybicki FJ, Manola JB, Tuncali K, Karshbaum SH, Singer S, Fletcher CD, Demetri GD: Liposarcoma subtypes: identification with computed tomography and ultrasound-guided percutaneous needle biopsy. Eur Radiol; 2005 Feb;15(2):383-9
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  • [Title] Liposarcoma subtypes: identification with computed tomography and ultrasound-guided percutaneous needle biopsy.
  • The purpose of the study was to evaluate the feasibility of image-guided percutaneous needle biopsy to enable specific subtype classification of liposarcoma in patients with previously diagnosed disease and compare the yield of fine and large needle techniques for each subtype.
  • We reviewed the medical records and pathology reports of 69 fine (20 g) needle and large (15, 16 g) needle biopsies performed in 44 patients enrolled in a clinical trial evaluating the effect of a novel therapy for advanced liposarcoma in the abdomen and pelvis.
  • The diagnostic yield (proportion of biopsies with correct subtype diagnosis) of percutaneous biopsy for identifying all subtypes of liposarcoma was 81% (64% for fine needles and 73% for large needles alone).
  • Accurate diagnostic subset classification of liposarcoma by percutaneous biopsy is feasible, although both fine and large needles should be used.
  • Although these data cannot be extrapolated to primary diagnosis of liposarcoma, they are important for screening and subtyping of possible recurrence.
  • [MeSH-major] Biopsy, Needle / methods. Liposarcoma / pathology
  • [MeSH-minor] Adult. Antineoplastic Agents / therapeutic use. Chromans / therapeutic use. Clinical Trials, Phase II as Topic. Feasibility Studies. Female. History, 18th Century. Humans. Male. Middle Aged. Radiography, Interventional. Thiazolidinediones / therapeutic use. Tomography, X-Ray Computed. Ultrasonography, Interventional

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  • (PMID = 15480688.001).
  • [ISSN] 0938-7994
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Comparative Study; Historical Article; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Chromans; 0 / Thiazolidinediones; I66ZZ0ZN0E / troglitazone
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43. Ramos Moreno E, Ortega Lozano S, Ramos Torres C, Gómez González J: [CT-PET application in the liposarcoma feature determination]. Rev Esp Med Nucl; 2007 Nov-Dec;26(6):372-3
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  • [Title] [CT-PET application in the liposarcoma feature determination].
  • [Transliterated title] Utilidad de la PET/TAC para la caracterización del liposarcoma.
  • [MeSH-major] Liposarcoma / diagnosis. Positron-Emission Tomography. Soft Tissue Neoplasms / diagnosis. Tomography, X-Ray Computed
  • [MeSH-minor] Adult. Female. Humans. Male. Middle Aged

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  • (PMID = 18021692.001).
  • [ISSN] 0212-6982
  • [Journal-full-title] Revista española de medicina nuclear
  • [ISO-abbreviation] Rev Esp Med Nucl
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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44. Rosner M, Yosepovich A, Paul M, Rosen N, Perelman M: Orbital well-differentiated liposarcoma demonstrating chromosomal imbalances. Eye (Lond); 2006 Jan;20(1):126-8
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  • [Title] Orbital well-differentiated liposarcoma demonstrating chromosomal imbalances.
  • [MeSH-major] Chromosome Aberrations. Liposarcoma / genetics. Neoplasm Recurrence, Local / genetics. Orbital Neoplasms / genetics
  • [MeSH-minor] Adult. Female. Humans. Nucleic Acid Hybridization

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  • (PMID = 15688045.001).
  • [ISSN] 0950-222X
  • [Journal-full-title] Eye (London, England)
  • [ISO-abbreviation] Eye (Lond)
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
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45. Nilbert M, Therkildsen C, Nissen A, Akerman M, Bernstein I: Sarcomas associated with hereditary nonpolyposis colorectal cancer: broad anatomical and morphological spectrum. Fam Cancer; 2009;8(3):209-13
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  • The median age at sarcoma diagnosis was 43 (15-74) years.
  • Soft tissue sarcomas predominated followed by uterine sarcomas and eight histopathological subtypes were represented with recurrent diagnoses of liposarcoma, leiomyosarcoma, and carcinosarcoma.
  • This suggests that sarcomas may be part of the HNPCC tumor spectrum and that colorectal cancer should be considered in the family history of sarcoma patients.
  • [MeSH-major] Colorectal Neoplasms, Hereditary Nonpolyposis / genetics. MutS Homolog 2 Protein / genetics. Sarcoma / genetics
  • [MeSH-minor] Adolescent. Adult. Aged. Colorectal Neoplasms / genetics. DNA Mismatch Repair. DNA Repair Enzymes / genetics. DNA-Binding Proteins / genetics. Endometrial Neoplasms / genetics. Female. Humans. Male. Middle Aged. Young Adult

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  • (PMID = 19130300.001).
  • [ISSN] 1573-7292
  • [Journal-full-title] Familial cancer
  • [ISO-abbreviation] Fam. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / DNA-Binding Proteins; 0 / G-T mismatch-binding protein; EC 3.6.1.3 / MutS Homolog 2 Protein; EC 6.5.1.- / DNA Repair Enzymes
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46. Paragis Sanchez T, Bannwart C, Murilo Araújo D, Dos Santos Pinto Júnior D, Thomé Capuano AC: Well-differentiated liposarcoma of the tongue. A case report. Minerva Stomatol; 2008 Jul-Aug;57(7-8):383-7
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  • [Title] Well-differentiated liposarcoma of the tongue. A case report.
  • Liposarcoma of the oral cavity is very rare.
  • The aim of this article is to present a case report of a well-differentiated lipoma-like liposarcoma of the tongue, in a 36-year-old woman, and to review the existing literature.
  • [MeSH-major] Liposarcoma / pathology. Tongue Neoplasms / pathology
  • [MeSH-minor] Adult. Female. Humans

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  • (PMID = 18784638.001).
  • [ISSN] 0026-4970
  • [Journal-full-title] Minerva stomatologica
  • [ISO-abbreviation] Minerva Stomatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 29
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47. Mankin HJ, Hornicek FJ: Diagnosis, classification, and management of soft tissue sarcomas. Cancer Control; 2005 Jan-Feb;12(1):5-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Sarcoma / diagnosis. Sarcoma / therapy
  • [MeSH-minor] Adolescent. Adult. Age Factors. Aged. Aged, 80 and over. Child. Child, Preschool. Female. Fibrosarcoma / diagnosis. Fibrosarcoma / therapy. Histiocytoma, Benign Fibrous / diagnosis. Histiocytoma, Benign Fibrous / therapy. Humans. Leiomyosarcoma / diagnosis. Leiomyosarcoma / therapy. Liposarcoma / diagnosis. Liposarcoma / therapy. Male. Middle Aged. Neoplasm Staging / methods. Neurofibrosarcoma / diagnosis. Neurofibrosarcoma / therapy. Outcome Assessment (Health Care). Rhabdomyosarcoma / diagnosis. Rhabdomyosarcoma / therapy. Sarcoma, Clear Cell / diagnosis. Sarcoma, Clear Cell / therapy. Sarcoma, Synovial / diagnosis. Sarcoma, Synovial / therapy. Survival Analysis

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  • (PMID = 15668648.001).
  • [ISSN] 1073-2748
  • [Journal-full-title] Cancer control : journal of the Moffitt Cancer Center
  • [ISO-abbreviation] Cancer Control
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 205
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48. Italiano A, Bianchini L, Keslair F, Bonnafous S, Cardot-Leccia N, Coindre JM, Dumollard JM, Hofman P, Leroux A, Mainguené C, Peyrottes I, Ranchere-Vince D, Terrier P, Tran A, Gual P, Pedeutour F: HMGA2 is the partner of MDM2 in well-differentiated and dedifferentiated liposarcomas whereas CDK4 belongs to a distinct inconsistent amplicon. Int J Cancer; 2008 May 15;122(10):2233-41
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  • The centromeric border of the CDK4 amplicon was located immediately downstream the 5' end of DDIT3, a gene known for being involved in myxoid liposarcoma translocations.
  • [MeSH-major] Cell Differentiation. Chromosomes, Human, Pair 12 / genetics. Cyclin-Dependent Kinase 4 / genetics. HMGA2 Protein / genetics. Liposarcoma / genetics. Proto-Oncogene Proteins c-mdm2 / genetics
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Gene Amplification. Humans. In Situ Hybridization, Fluorescence. Lipoma / genetics. Lipoma / pathology. Male. Middle Aged. Neoplasm Proteins / genetics. RNA, Messenger / genetics. RNA, Messenger / metabolism. Reverse Transcriptase Polymerase Chain Reaction. Transcription Factor CHOP / genetics. Transcription Factors / genetics

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  • [Copyright] (c) 2008 Wiley-Liss, Inc.
  • (PMID = 18214854.001).
  • [ISSN] 1097-0215
  • [Journal-full-title] International journal of cancer
  • [ISO-abbreviation] Int. J. Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DDIT3 protein, human; 0 / HMGA2 Protein; 0 / Neoplasm Proteins; 0 / RNA, Messenger; 0 / Transcription Factors; 0 / YEATS4 protein, human; 147336-12-7 / Transcription Factor CHOP; EC 2.7.11.22 / CDK4 protein, human; EC 2.7.11.22 / Cyclin-Dependent Kinase 4; EC 6.3.2.19 / MDM2 protein, human; EC 6.3.2.19 / Proto-Oncogene Proteins c-mdm2
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49. de Wijn RS, van der Heijden EP, Kon M: On lipoma of the buccal fat pad: report of two cases and review of the literature. J Plast Reconstr Aesthet Surg; 2009 Jan;62(1):28-35
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  • More importantly, well-differentiated liposarcoma of the BFP has also been described, which may be clinically and histologically indistinguishable from spindle-cell lipoma.
  • Detailed knowledge of the anatomy and extensive MR-imaging are paramount in guiding the surgical approach by visualising the extent of growth in the various extensions, and determining if the radiological picture is suggestive of liposarcoma.
  • [MeSH-minor] Adult. Cheek. Female. Humans. Infant. Magnetic Resonance Imaging. Middle Aged. Neoplasm Recurrence, Local / pathology

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  • (PMID = 18249050.001).
  • [ISSN] 1878-0539
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 63
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50. Prud'homme A, Rousselot C, de Pinieux G, Voche P, Rosset P: [Hemosiderotic fibrohistiocytic lipomatous lesion: a new entity you must remind]. Ann Chir Plast Esthet; 2007 Dec;52(6):616-20
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  • Fatty tissues lesions are the most frequent of both benign (lipoma) and malignant tumor (liposarcoma) of soft tissues in the adult.
  • [MeSH-minor] Adult. Female. Foot. Humans

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  • (PMID = 17316948.001).
  • [ISSN] 0294-1260
  • [Journal-full-title] Annales de chirurgie plastique et esthétique
  • [ISO-abbreviation] Ann Chir Plast Esthet
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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51. Esaki M, Moriya Y: A case of huge liposarcoma in the abdomen. Jpn J Clin Oncol; 2006 Aug;36(8):532
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  • [Title] A case of huge liposarcoma in the abdomen.
  • [MeSH-major] Liposarcoma / radiography. Retroperitoneal Neoplasms / radiography. Tomography, X-Ray Computed
  • [MeSH-minor] Adult. Humans. Male. Radiography, Abdominal

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  • (PMID = 16935863.001).
  • [ISSN] 0368-2811
  • [Journal-full-title] Japanese journal of clinical oncology
  • [ISO-abbreviation] Jpn. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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52. Gupta R, Khurana N, Singh S, Meher R: Primary chordoma of the nasal cavity: a rare site of presentation. Pathology; 2007 Apr;39(2):273-5
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  • [MeSH-minor] Adenocarcinoma / pathology. Adult. Chondrosarcoma / pathology. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Liposarcoma / pathology. Tomography, X-Ray Computed

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  • (PMID = 17454763.001).
  • [ISSN] 0031-3025
  • [Journal-full-title] Pathology
  • [ISO-abbreviation] Pathology
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
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53. Penel N, Grosjean J, Robin YM, Vanseymortier L, Clisant S, Adenis A: Frequency of certain established risk factors in soft tissue sarcomas in adults: a prospective descriptive study of 658 cases. Sarcoma; 2008;2008:459386
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  • Liposarcoma, the most frequent histological subtype observed, is not associated with any particular aetiological entity.
  • Finally, most of the adult soft tissue sarcomas are not related to any classical clinically identified genetic disease or previous radiation therapy and/or chronic lymphoedema risk factors.

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  • (PMID = 18497869.001).
  • [ISSN] 1357-714X
  • [Journal-full-title] Sarcoma
  • [ISO-abbreviation] Sarcoma
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
  • [Other-IDs] NLM/ PMC2386887
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54. Fang ZW, Chen J, Teng S, Chen Y, Xue RF: Analysis of soft tissue sarcomas in 1118 cases. Chin Med J (Engl); 2009 Jan 5;122(1):51-3
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  • The present study was conducted to determine the relative frequency of each type of soft tissue sarcoma.
  • [MeSH-major] Sarcoma / epidemiology. Soft Tissue Neoplasms / epidemiology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Female. Histiocytoma, Malignant Fibrous / diagnosis. Histiocytoma, Malignant Fibrous / epidemiology. Humans. Infant. Infant, Newborn. Liposarcoma / diagnosis. Liposarcoma / epidemiology. Male. Middle Aged. Rhabdomyosarcoma / diagnosis. Rhabdomyosarcoma / epidemiology. Sarcoma, Synovial / diagnosis. Sarcoma, Synovial / epidemiology. Young Adult

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  • (PMID = 19187617.001).
  • [ISSN] 0366-6999
  • [Journal-full-title] Chinese medical journal
  • [ISO-abbreviation] Chin. Med. J.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
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55. Singh A, Chatterjee P, Pai MC, Chacko RT: Gastrointestinal stromal tumours: a clinico-radiologic review from a single centre in South India. J Med Imaging Radiat Oncol; 2009 Dec;53(6):522-9
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  • We also highlight some unusual CT features of these tumours that we encountered during the study, such as the presence of metastatic lymphadenopathy and satellite nodules, relapse in appendices epiploicae of the bowel, metachronous liposarcoma, adrenal and lung metastases, multiplicity of lesions and aneurysmal dilatation of the bowel.
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Female. Humans. India. Male. Middle Aged. Young Adult

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  • (PMID = 20002283.001).
  • [ISSN] 1754-9485
  • [Journal-full-title] Journal of medical imaging and radiation oncology
  • [ISO-abbreviation] J Med Imaging Radiat Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Australia
  • [Number-of-references] 24
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56. Ghert MA, Davis AM, Griffin AM, Alyami AH, White L, Kandel RA, Ferguson P, O'Sullivan B, Catton CN, Lindsay T, Rubin B, Bell RS, Wunder JS: The surgical and functional outcome of limb-salvage surgery with vascular reconstruction for soft tissue sarcoma of the extremity. Ann Surg Oncol; 2005 Dec;12(12):1102-10
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  • [Title] The surgical and functional outcome of limb-salvage surgery with vascular reconstruction for soft tissue sarcoma of the extremity.
  • BACKGROUND: This study compared the surgical, oncological, and functional outcomes of patients undergoing limb-salvage surgery for extremity soft tissue sarcoma with vascular resection and reconstruction with the outcomes of those undergoing limb-salvage without vascular reconstruction.
  • METHODS: Nineteen patients were identified from a prospective soft-tissue sarcoma database who underwent vascular resection and reconstruction as part of their limb-salvage surgery and who were followed up for at least 1 year or until death.
  • CONCLUSIONS: Vascular reconstruction is a feasible option in limb-salvage surgery for soft tissue sarcoma but is associated with an increased risk for postoperative complications, including amputation.
  • [MeSH-major] Limb Salvage. Sarcoma / surgery. Soft Tissue Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Case-Control Studies. Female. Histiocytoma, Benign Fibrous / surgery. Humans. Leg / innervation. Liposarcoma / surgery. Male. Middle Aged. Reconstructive Surgical Procedures. Recovery of Function. Retrospective Studies. Surgical Flaps. Treatment Outcome. Vascular Surgical Procedures

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  • (PMID = 16252136.001).
  • [ISSN] 1068-9265
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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57. Herrera-Gómez A, Ortega-Gutiérrez C, Betancourt AM, Luna-Ortiz K: Giant retroperitoneal liposarcoma. World J Surg Oncol; 2008;6:115
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  • [Title] Giant retroperitoneal liposarcoma.
  • BACKGROUND: Liposarcoma is the most frequent histopathological variety of the retroperitoneum, surgery is the gold standard for treatment.
  • CASE PRESENTATION: We present the case of a 24-year-old male who was diagnosed with a giant retroperitoneal liposarcoma.
  • [MeSH-major] Liposarcoma / pathology. Retroperitoneal Neoplasms / pathology
  • [MeSH-minor] Adult. Humans. Male. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 18976464.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2644689
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58. Murphey MD, Arcara LK, Fanburg-Smith J: From the archives of the AFIP: imaging of musculoskeletal liposarcoma with radiologic-pathologic correlation. Radiographics; 2005 Sep-Oct;25(5):1371-95
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  • [Title] From the archives of the AFIP: imaging of musculoskeletal liposarcoma with radiologic-pathologic correlation.
  • Liposarcoma is the second most common type of soft-tissue sarcoma, accounting for 10%-35% of these lesions.
  • The CT or MR imaging finding of a nodular dominant focus (>1 cm in size) of nonlipomatous tissue in a well-differentiated liposarcoma suggests dedifferentiated liposarcoma, and biopsy should be directed at the nonadipose component.
  • The high water content of myxoid liposarcoma seen at pathologic analysis and constituting the majority of the lesion is reflected at sonography, CT, and MR imaging.
  • Primary liposarcoma of bone is exceedingly rare and usually demonstrates aggressive nonspecific features, although fat may be seen.
  • Understanding and recognition of the spectrum of appearances of the various types of musculoskeletal liposarcoma, which reflect their underlying pathologic characteristics, improves radiologic assessment and is vital for optimal patient management.
  • [MeSH-major] Liposarcoma / diagnosis. Magnetic Resonance Imaging. Soft Tissue Neoplasms / diagnosis. Tomography, X-Ray Computed
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Male. Middle Aged

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  • (PMID = 16160117.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 89
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59. Singh NK, Kolluri R: Liposarcoma of thigh presenting as deep venous thrombosis. Phlebology; 2009 Jun;24(3):139-41
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  • [Title] Liposarcoma of thigh presenting as deep venous thrombosis.
  • RESULTS: Imaging and biopsy revealed a 5 x 11 cm myxoid liposarcoma, adherent to the vein, that was the cause of her persistent symptoms despite anticoagulation, possibly by its local mass effect and also by its potential to create a thrombogenic milieu.


60. Kawano R, Nishie A, Yoshimitsu K, Irie H, Tajima T, Hirakawa M, Ishigami K, Ushijima Y, Okamoto D, Yabuuchi H, Taketomi A, Nishihara Y, Fujita N, Honda H: Retroperitoneal well-differentiated inflammatory liposarcoma: a diagnostic dilemma. Radiat Med; 2008 Aug;26(7):450-3
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  • [Title] Retroperitoneal well-differentiated inflammatory liposarcoma: a diagnostic dilemma.
  • We present a case of retroperitoneal well-differentiated inflammatory liposarcoma that was extremely difficult to diagnose preoperatively.
  • The preoperative working diagnosis was malignant lymphoma or inflammatory pseudotumor, whereas the final diagnosis after surgery was well-differentiated inflammatory liposarcoma.
  • As a result, only a large component of lymphoid infiltration was recognized as a tumor preoperatively, and minimal fat stranding represented a component of lipoma-like liposarcoma.
  • [MeSH-major] Liposarcoma / diagnosis. Retroperitoneal Neoplasms / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. Rare Diseases. Retroperitoneal Space / diagnostic imaging. Retroperitoneal Space / pathology. Soft Tissue Neoplasms / diagnosis. Tomography, X-Ray Computed

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  • (PMID = 18770006.001).
  • [ISSN] 0288-2043
  • [Journal-full-title] Radiation medicine
  • [ISO-abbreviation] Radiat Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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61. Park JO, Qin LX, Prete FP, Antonescu C, Brennan MF, Singer S: Predicting outcome by growth rate of locally recurrent retroperitoneal liposarcoma: the one centimeter per month rule. Ann Surg; 2009 Dec;250(6):977-82
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  • [Title] Predicting outcome by growth rate of locally recurrent retroperitoneal liposarcoma: the one centimeter per month rule.
  • OBJECTIVE: To identify the prognostic variables that predict disease-specific survival and second local recurrence-free survival in patients with recurrent retroperitoneal liposarcoma so as to guide clinical management.
  • SUMMARY BACKGROUND DATA: Local recurrence after complete resection of primary retroperitoneal liposarcoma is a common clinical problem that frequently leads to morbidity and mortality.
  • METHODS: From a prospective sarcoma database we selected 105 patients who had at least one local recurrence following complete resection of a primary retroperitoneal liposarcoma between July 1982 and December 2005.
  • CONCLUSIONS: Local recurrence growth rate is strongly associated with disease-specific survival and local control for patients with completely resected locally recurrent retroperitoneal liposarcoma.

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  • (PMID = 19953716.001).
  • [ISSN] 1528-1140
  • [Journal-full-title] Annals of surgery
  • [ISO-abbreviation] Ann. Surg.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P01 CA047179; United States / NCI NIH HHS / CA / P01 CA047179-17; United States / NCI NIH HHS / CA / P01CA47179
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS344379; NLM/ PMC3248745
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62. Hirata K, Kanemitsu S, Nakayama Y, Nagata N, Itoh H, Ohnishi H, Ishikawa H, Furukawa Y, HNPCC registry and genetic testing project of the Japanese Society for Cancer of the Colon and Rectum (JSCCR): A novel germline mutation of MSH2 in a hereditary nonpolyposis colorectal cancer patient with liposarcoma. Am J Gastroenterol; 2006 Jan;101(1):193-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A novel germline mutation of MSH2 in a hereditary nonpolyposis colorectal cancer patient with liposarcoma.
  • Among extracolonic tumors, a limited number of soft tissue sarcomas associated with HNPCC have been reported, and the mechanism underlying liposarcoma in HNPCC patients remains unclear.
  • AIM: We herein report the case of a HNPCC patient with liposarcoma, with the goal of elucidating the involvement of a mismatch repair deficiency in the tumor.
  • METHODS AND RESULTS: A 40-yr-old Japanese patient, who had a past history of adenocarcinoma of the rectum and transitional cell carcinoma of the urinary bladder, developed a liposarcoma in his left thigh.
  • The expression of MSH2 in the liposarcoma and rectal cancer of the patient was analyzed by immunohistochemistry, which revealed loss of MSH2 expression in the tumors.
  • To investigate whether the loss of MSH2 was a common feature of liposarcoma, we examined the MSH2 expression in an additional two sporadic liposarcomas, both of which were stained with anti-MSH2 antibody.
  • Since an immunohistochemical analysis showed no nuclear staining for MSH2 protein in the liposarcoma as well as the rectal cancer, the loss of wild-type MSH2 protein was thus considered to possibly play a role in the development of liposarcoma in HNPCC patients.
  • [MeSH-major] Colorectal Neoplasms, Hereditary Nonpolyposis / genetics. Liposarcoma / pathology. Muscle Neoplasms / pathology. MutS Homolog 2 Protein / genetics. Neoplasms, Multiple Primary / pathology. Urinary Bladder Neoplasms / pathology
  • [MeSH-minor] Adult. Base Pair Mismatch. Carcinoma, Transitional Cell / diagnosis. Carcinoma, Transitional Cell / pathology. Follow-Up Studies. Germ-Line Mutation. Humans. Male. Risk Assessment


63. Zhang YQ, Yao LQ, Qin XY, Zhou PH, Xu MD, Hou YY: [Diagnosis and treatment of gastrointestinal lipoma]. Zhonghua Wei Chang Wai Ke Za Zhi; 2007 Nov;10(6):512-4
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  • No recurrence and metastasis were observed except one case dying of gastric liposarcoma.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Endoscopy, Gastrointestinal. Endosonography. Female. Humans. Male. Middle Aged. Retrospective Studies

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  • (PMID = 18000767.001).
  • [ISSN] 1671-0274
  • [Journal-full-title] Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
  • [ISO-abbreviation] Zhonghua Wei Chang Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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64. Willeke F, Assad A, Findeisen P, Schromm E, Grobholz R, von Gerstenbergk B, Mantovani A, Peri S, Friess HH, Post S, von Knebel Doeberitz M, Schwarzbach MH: Overexpression of a member of the pentraxin family (PTX3) in human soft tissue liposarcoma. Eur J Cancer; 2006 Oct;42(15):2639-46
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Overexpression of a member of the pentraxin family (PTX3) in human soft tissue liposarcoma.
  • A unique feature of human soft tissue liposarcoma is a stable (12;16)(q13;p11) translocation observed mainly in myxoid and roundcell liposarcomas.
  • Finally, PTX3 expression was not related to presence of a FUS/CHOP fusion transcript within the liposarcoma tissues.
  • PTX3 has been associated with adipocyte differentiation and now, additionally, is characterised by a markedly increased expression in human soft tissue liposarcoma.
  • This finding mandates further research efforts to clarify the exact role of PTX3 in liposarcoma oncogenesis.
  • [MeSH-major] C-Reactive Protein / metabolism. Liposarcoma / genetics. Neoplasm Proteins / metabolism. Serum Amyloid P-Component / metabolism
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Blotting, Western. Cohort Studies. Female. Humans. Immunohistochemistry. Male. Middle Aged. Oncogene Proteins, Fusion / metabolism. RNA-Binding Protein FUS / metabolism. Reverse Transcriptase Polymerase Chain Reaction. Transcription Factor CHOP / metabolism. Translocation, Genetic

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  • (PMID = 16959485.001).
  • [ISSN] 0959-8049
  • [Journal-full-title] European journal of cancer (Oxford, England : 1990)
  • [ISO-abbreviation] Eur. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Neoplasm Proteins; 0 / Oncogene Proteins, Fusion; 0 / RNA-Binding Protein FUS; 0 / Serum Amyloid P-Component; 0 / TLS-CHOP fusion protein, human; 147336-12-7 / Transcription Factor CHOP; 148591-49-5 / PTX3 protein; 9007-41-4 / C-Reactive Protein
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65. Karavasilis V, Seddon BM, Ashley S, Al-Muderis O, Fisher C, Judson I: Significant clinical benefit of first-line palliative chemotherapy in advanced soft-tissue sarcoma: retrospective analysis and identification of prognostic factors in 488 patients. Cancer; 2008 Apr 1;112(7):1585-91
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  • [Title] Significant clinical benefit of first-line palliative chemotherapy in advanced soft-tissue sarcoma: retrospective analysis and identification of prognostic factors in 488 patients.
  • METHODS: Patients with STS who had first-line chemotherapy for advanced and/or metastatic disease between 1991 and 2005 were identified from the Royal Marsden Hospital's sarcoma database.
  • Patients with Ewing sarcoma, rhabdomyosarcoma, desmoplastic small round cell tumor, and gastrointestinal stromal tumors were excluded from the study.
  • The most common histologic subtypes were leiomyosarcoma (35%) synovial sarcoma (13%), liposarcoma (10%), and malignant fibrous histiocytoma (10%).
  • An objective response was reported in 33% of patients (53% in those with synovial sarcoma); 22% had stable disease and 45% derived 'clinical benefit' (objective responses + stable disease for >or= 6 months).
  • In multivariate analysis, age <40 years, liposarcoma, and synovial histology were found to be positive, and bone involvement to be negative, independent prognostic factors.
  • Synovial sarcoma and liposarcoma subtypes have a better prognosis.
  • [MeSH-major] Sarcoma / drug therapy. Soft Tissue Neoplasms / drug therapy
  • [MeSH-minor] Adolescent. Adult. Aged. Antineoplastic Combined Chemotherapy Protocols. Bone Neoplasms / drug therapy. Bone Neoplasms / secondary. Chemotherapy, Adjuvant. Female. Follow-Up Studies. Humans. Liver Neoplasms / drug therapy. Liver Neoplasms / secondary. Lung Neoplasms / drug therapy. Lung Neoplasms / secondary. Male. Middle Aged. Neoplasm Staging. Palliative Care. Prognosis. Prospective Studies. Retrospective Studies. Survival Rate

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  • (PMID = 18278813.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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66. Gong YL, Li T, Guo H, Sun Y, Chi YK, Ling Y, Shen Q, Liu HJ, Hou L, Zhang B: [Expression of TEIF protein in soft tissue tumors and its significance]. Zhonghua Bing Li Xue Za Zhi; 2006 Nov;35(11):651-5
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  • The positive staining was predominantly in synovial sarcoma 94% (16/17), primitive neuroectodermal tumor (PNET) 91% (21/23), both of which were significantly higher than 43% (6/14) of dermatofibrosarcoma protuberans, 38% (6/16) of myxofibrosarcoma, 36% (8/22) of malignant peripheral nerve sheath tumor, 32% (6/19) of liposarcoma, (P < 0.05, respectively), but not higher than 75% (15/20) of malignant fibrous histiocytoma, 70% (7/10) of rhabdomyosarcoma or 64% (9/14) of leiomyosarcoma.
  • Meanwhile, strong positive staining of TEIF (>or= 2+) was frequently observed in PNET (83%, 19/23) and synovial sarcoma (76%, 13/17).
  • With respect to FNCLCC grading, 19 cases of grade I sarcoma TEIF was 32% (6/19) and strong positive was 11% (2/19), 44 cases of grade II sarcoma was 48% (21/44) and 32% (14/44), and 70 of grade III was 84% (59/70) and 70% (49/70).
  • The rate of either positive or strong positive in grade III sarcoma was significantly different from that of either grade I or II (P < 0.05), but no difference between the latter two groups (P > 0.05).
  • [MeSH-major] Sarcoma / metabolism. Soft Tissue Neoplasms / metabolism. Transcription Factors / biosynthesis
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Blotting, Western. Cell Line, Tumor. Child. Child, Preschool. Female. HeLa Cells. Histiocytoma, Malignant Fibrous / metabolism. Histiocytoma, Malignant Fibrous / pathology. Humans. Immunohistochemistry. Infant. Leiomyoma / metabolism. Leiomyoma / pathology. Male. Middle Aged. Neuroectodermal Tumors, Primitive / metabolism. Neuroectodermal Tumors, Primitive / pathology. Rhabdomyosarcoma / metabolism. Rhabdomyosarcoma / pathology. Sarcoma, Synovial / metabolism. Sarcoma, Synovial / pathology. Tissue Array Analysis. Young Adult

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  • (PMID = 17374207.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Transcription Factors; EC 2.7.1.- / SCYL1 protein, human
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67. Billing V, Mertens F, Domanski HA, Rydholm A: Deep-seated ordinary and atypical lipomas: histopathology, cytogenetics, clinical features, and outcome in 215 tumours of the extremity and trunk wall. J Bone Joint Surg Br; 2008 Jul;90(7):929-33
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  • The low recurrence rate of deep-seated lipomas of the extremity or trunk wall, irrespective of histological subtype, implies that if surgery is indicated, the tumour may be shelled out, that atypical lipomas in these locations do not deserve the designation well-differentiated liposarcoma, and that routine review after surgery is not required.
  • [MeSH-minor] Adolescent. Adult. Age Distribution. Aged. Aged, 80 and over. Child. Cytogenetics / methods. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Neoplasm Staging. Statistics, Nonparametric. Treatment Outcome

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  • (PMID = 18591605.001).
  • [ISSN] 0301-620X
  • [Journal-full-title] The Journal of bone and joint surgery. British volume
  • [ISO-abbreviation] J Bone Joint Surg Br
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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68. Tanaka M, Sawai H, Okada Y, Yamamoto M, Funahashi H, Hayakawa T, Takeyama H, Manabe T: Malignant solitary fibrous tumor originating from the peritoneum and review of the literature. Med Sci Monit; 2006 Oct;12(10):CS95-8
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  • Liposarcoma originating from the retroperitoneum was suggested, and the patient underwent a complete resection of the tumor as well as the left kidney because tumor invasion of the upper left kidney was suspected.
  • [MeSH-minor] Adult. Antigens, CD34 / metabolism. Female. Follow-Up Studies. Humans. Immunohistochemistry. Time Factors. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 17006407.001).
  • [ISSN] 1234-1010
  • [Journal-full-title] Medical science monitor : international medical journal of experimental and clinical research
  • [ISO-abbreviation] Med. Sci. Monit.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Antigens, CD34
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69. Pakos EE, Gogou PV, Apostolikas N, Batistatou A, Tsekeris PG: Factors associated with outcome in liposarcomas of the extremities and trunk. J BUON; 2010 Jul-Sep;15(3):518-23
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  • METHODS: Sixty-three surgically treated patients with liposarcoma, with mean age 53 years, were included in this study.
  • CONCLUSION: Patients with liposarcoma surviving for 5 years, have also a high probability to be alive at 10 years.
  • [MeSH-major] Liposarcoma / mortality. Soft Tissue Neoplasms / mortality
  • [MeSH-minor] Adult. Aged. Extremities. Female. Humans. Male. Middle Aged. Neoplasm Metastasis. Neoplasm Recurrence, Local. Proportional Hazards Models. Retrospective Studies. Risk Factors. Survival Rate

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  • (PMID = 20941821.001).
  • [ISSN] 1107-0625
  • [Journal-full-title] Journal of B.U.ON. : official journal of the Balkan Union of Oncology
  • [ISO-abbreviation] J BUON
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
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70. Wibmer C, Leithner A, Zielonke N, Sperl M, Windhager R: Increasing incidence rates of soft tissue sarcomas? A population-based epidemiologic study and literature review. Ann Oncol; 2010 May;21(5):1106-11
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  • The most common histotypes were sarcoma not otherwise specified (36%), leiomyosarcoma (24%), liposarcoma (12%), malignant fibrous histiocytoma (9%) and fibrosarcoma (5%).
  • Different inclusion criteria (Kaposi's sarcoma and dermatofibrosarcoma) and classifications in the various studies explain the increase of incidence in some studies rather than true increase of STS due to new or accumulated risk factors.

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  • (PMID = 19858086.001).
  • [ISSN] 1569-8041
  • [Journal-full-title] Annals of oncology : official journal of the European Society for Medical Oncology
  • [ISO-abbreviation] Ann. Oncol.
  • [Language] ENG
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 17
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71. Davidović LB, Sindjelić RB, Savić NB, Kostić DM, Svetković SD, Kuzmanović IB, Marković DM, Marković MM, Cinara IS, Maksimović ZL: [Surgical treatment of abdominal tumours closely related to major blood vessels]. Srp Arh Celok Lek; 2008 May-Jun;136(5-6):241-7
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  • Histologically, the most frequent were the following: renal carcinoma in 14 patients, teratoma in 7, liposarcoma in 5, fibrosarcoma and lymphoma in 3 patients.
  • [MeSH-minor] Adolescent. Adult. Aged. Blood Vessel Prosthesis Implantation. Child. Female. Humans. Male. Middle Aged. Neoplasm Invasiveness

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  • (PMID = 18792619.001).
  • [ISSN] 0370-8179
  • [Journal-full-title] Srpski arhiv za celokupno lekarstvo
  • [ISO-abbreviation] Srp Arh Celok Lek
  • [Language] srp
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Serbia
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72. Engström K, Bergh P, Cederlund CG, Hultborn R, Willen H, Aman P, Kindblom LG, Meis-Kindblom JM: Irradiation of myxoid/round cell liposarcoma induces volume reduction and lipoma-like morphology. Acta Oncol; 2007;46(6):838-45
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  • [Title] Irradiation of myxoid/round cell liposarcoma induces volume reduction and lipoma-like morphology.
  • The aim of the study was to investigate the clinical and morphological effects of radiotherapy in the treatment of myxoid/round cell liposarcoma (MLS/RCLS).
  • [MeSH-major] Liposarcoma, Myxoid / radiotherapy
  • [MeSH-minor] Adult. Aged. Biomarkers, Tumor. Biopsy, Fine-Needle. Disease Progression. Female. Humans. Male. Middle Aged. Preoperative Care. Prospective Studies. Treatment Outcome

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  • (PMID = 17653909.001).
  • [ISSN] 0284-186X
  • [Journal-full-title] Acta oncologica (Stockholm, Sweden)
  • [ISO-abbreviation] Acta Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Norway
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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73. Boland JM, Weiss SW, Oliveira AM, Erickson-Johnson ML, Folpe AL: Liposarcomas with mixed well-differentiated and pleomorphic features: a clinicopathologic study of 12 cases. Am J Surg Pathol; 2010 Jun;34(6):837-43
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  • Pleomorphic liposarcoma (PL) is an undifferentiated pleomorphic sarcoma containing pleomorphic lipoblasts.
  • PL almost always arises de novo without an associated low-grade precursor lesion [eg, well-differentiated liposarcoma (WDL)].
  • We have, however, observed rare cases of PL, which arose in association with WDL and have studied these cases to define their clinicopathologic features and their nosologic relationship to other forms of liposarcoma.
  • Tumors consisted predominately of typical WDL, with an "abrupt" transition to pleomorphic spindle cell sarcoma containing pleomorphic lipoblasts.
  • [MeSH-major] Liposarcoma / genetics. Liposarcoma / pathology. Proto-Oncogene Proteins c-mdm2 / genetics. Soft Tissue Neoplasms / genetics. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Gene Amplification. Humans. In Situ Hybridization, Fluorescence. Male. Middle Aged. Prognosis

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  • (PMID = 20431480.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] EC 6.3.2.19 / MDM2 protein, human; EC 6.3.2.19 / Proto-Oncogene Proteins c-mdm2
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74. Lehnhardt M, Daigeler A, Homann HH, Hauser J, Langer S, Steinsträsser L, Soimaru C, Puls A, Steinau HU: [Importance of specialized centers in diagnosis and treatment of extremity-soft tissue sarcomas. Review of 603 cases]. Chirurg; 2009 Apr;80(4):341-7
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  • Liposarcoma and malignant fibrous histiocytoma were the most often diagnosed subgroups at 24% and 22.6%, respectively.
  • In the eight most frequent sarcoma types, malignant peripheral nerve sheath tumors and leiomyosarcoma had the highest rates of false primary diagnosis, 78.4% and 74.2% of cases, respectively.
  • [MeSH-major] Cancer Care Facilities. Extremities / surgery. Hospitals, Special. Hospitals, University. Sarcoma / diagnosis. Sarcoma / surgery. Soft Tissue Neoplasms / diagnosis. Soft Tissue Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Chemotherapy, Adjuvant. Child. Combined Modality Therapy. Diagnostic Errors. Female. Germany. Histiocytoma, Benign Fibrous / diagnosis. Histiocytoma, Benign Fibrous / pathology. Histiocytoma, Benign Fibrous / surgery. Humans. Leiomyosarcoma / diagnosis. Leiomyosarcoma / pathology. Leiomyosarcoma / surgery. Liposarcoma / diagnosis. Liposarcoma / pathology. Liposarcoma / surgery. Male. Middle Aged. Neoplasm Staging. Nerve Sheath Neoplasms / diagnosis. Nerve Sheath Neoplasms / pathology. Nerve Sheath Neoplasms / surgery. Radiotherapy, Adjuvant. Referral and Consultation. Retrospective Studies. Young Adult

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  • (PMID = 18523742.001).
  • [ISSN] 1433-0385
  • [Journal-full-title] Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen
  • [ISO-abbreviation] Chirurg
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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75. Charfi L, Driss M, Mrad K, Abbes I, Dhouib R, Sassi S, Ben Romdhane K: Primary well differentiated liposarcoma: an unusual tumor in the breast. Breast J; 2009 Mar-Apr;15(2):206-7
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  • [Title] Primary well differentiated liposarcoma: an unusual tumor in the breast.
  • [MeSH-major] Breast Neoplasms / pathology. Liposarcoma / pathology
  • [MeSH-minor] Adipocytes / pathology. Adult. Cell Differentiation. Cell Division. Cell Size. Female. Humans. Mammography. Mastectomy, Segmental. Treatment Outcome

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  • (PMID = 19292812.001).
  • [ISSN] 1524-4741
  • [Journal-full-title] The breast journal
  • [ISO-abbreviation] Breast J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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76. Chiò A, Restagno G, Brunetti M, Ossola I, Calvo A, Mora G, Sabatelli M, Monsurrò MR, Battistini S, Mandrioli J, Salvi F, Spataro R, Schymick J, Traynor BJ, La Bella V, ITALSGEN Consortium: Two Italian kindreds with familial amyotrophic lateral sclerosis due to FUS mutation. Neurobiol Aging; 2009 Aug;30(8):1272-5
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  • Recently, fused in sarcoma/translated in liposarcoma (FUS/TLS) gene, located on chromosome 16p11.2, has been identified as a disease gene in familial amyotrophic lateral sclerosis (FALS).

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  • (PMID = 19450904.001).
  • [ISSN] 1558-1497
  • [Journal-full-title] Neurobiology of aging
  • [ISO-abbreviation] Neurobiol. Aging
  • [Language] ENG
  • [Grant] United States / NIA NIH HHS / AG / Z01 AG000949; United States / Intramural NIH HHS / / Z99 AG999999; United States / NIA NIH HHS / AG / Z01-AG000949-02
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / RNA-Binding Protein FUS
  • [Other-IDs] NLM/ NIHMS128978; NLM/ PMC2771748
  • [Investigator] Giannini F; Ricci C; Moglia C; Lombardo F; Sbaiz L; Cammarosano S; Tedeschi G; Sola P; Bartolomei I; Marinou K; Papetti L; Conte A; Luigetti M; Paladino P; Caponnetto C; Siciliano G
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77. Costa A, Daidone MG, Daprai L, Villa R, Cantù S, Pilotti S, Mariani L, Gronchi A, Henson JD, Reddel RR, Zaffaroni N: Telomere maintenance mechanisms in liposarcomas: association with histologic subtypes and disease progression. Cancer Res; 2006 Sep 1;66(17):8918-24
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  • We proposed to define the prevalence of the two telomere maintenance mechanisms (TMM), to assess their association with histology, and to compare their prognostic relevance in a series of 93 patients with liposarcoma.
  • ALT or TA was found in 25.9% or 26.6% of 139 tested liposarcoma lesions, respectively.
  • [MeSH-major] Liposarcoma / pathology. Telomere / metabolism
  • [MeSH-minor] Adult. Biomarkers. Disease Progression. Female. Humans. Male. Middle Aged. Retrospective Studies. Survival Analysis. Survivors

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  • (PMID = 16951210.001).
  • [ISSN] 1538-7445
  • [Journal-full-title] Cancer research
  • [ISO-abbreviation] Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers
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78. Cox TC, Pearl JP, Ritter EM: Rives-Stoppa incisional hernia repair combined with laparoscopic separation of abdominal wall components: a novel approach to complex abdominal wall closure. Hernia; 2010 Dec;14(6):561-7
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  • The other patients included hernia after esophagectomy, retroperitoneal liposarcoma resection, and complicated diverticulitis.
  • [MeSH-minor] Adult. Aged. Female. Humans. Laparoscopy. Male. Middle Aged. Retrospective Studies. Surgical Mesh

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  • [Cites] Hernia. 2008 Apr;12(2):141-5 [18026686.001]
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  • (PMID = 20661611.001).
  • [ISSN] 1248-9204
  • [Journal-full-title] Hernia : the journal of hernias and abdominal wall surgery
  • [ISO-abbreviation] Hernia
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] France
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79. Fernández-Aceñero MJ, Larach F, Ortega-Fernández C: Non-epithelial lesions of the larynx: review of the 10-year experience in a tertiary Spanish hospital. Acta Otolaryngol; 2009 Jan;129(1):108-12
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  • We had two cases of chondrosarcoma, one case of liposarcoma, one case of synovial sarcoma, and one neural benign tumor, suggestive of neurinoma.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Chondrosarcoma / pathology. Chondrosarcoma / radiotherapy. Chondrosarcoma / surgery. Female. Granuloma, Plasma Cell / pathology. Granuloma, Plasma Cell / radiotherapy. Granuloma, Plasma Cell / surgery. Humans. Liposarcoma / pathology. Liposarcoma / radiotherapy. Liposarcoma / surgery. Lymphoma, Non-Hodgkin / pathology. Lymphoma, Non-Hodgkin / radiotherapy. Lymphoma, Non-Hodgkin / surgery. Male. Middle Aged. Neurilemmoma / pathology. Neurilemmoma / radiotherapy. Neurilemmoma / surgery. Plasmacytoma / pathology. Plasmacytoma / radiotherapy. Plasmacytoma / surgery. Retrospective Studies. Sarcoma, Synovial / pathology. Sarcoma, Synovial / radiotherapy. Sarcoma, Synovial / surgery. Spain. Vocal Cords / pathology. Vocal Cords / surgery. Young Adult

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  • (PMID = 18607979.001).
  • [ISSN] 1651-2251
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Norway
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80. Muth A, Persson F, Jansson S, Johanson V, Ahlman H, Wängberg B: Prognostic factors for survival after surgery for adrenal metastasis. Eur J Surg Oncol; 2010 Jul;36(7):699-704
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  • RESULTS: The tumour diagnoses were RCC n = 9, malignant melanoma n = 5, non-small-cell lung cancer n = 5, colorectal carcinoma n = 4, foregut carcinoid n = 2, adrenocortical carcinoma, breast cancer, hepatocellular carcinoma, urothelial carcinoma, and liposarcoma (one each); nine adrenal metastases were synchronous and 21 metachronous.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Kaplan-Meier Estimate. Laparoscopy. Male. Middle Aged. Neoplasm Staging. Predictive Value of Tests. Prognosis. Retrospective Studies. Risk Factors. Treatment Outcome

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  • (PMID = 20452170.001).
  • [ISSN] 1532-2157
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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81. Takahira T, Oda Y, Tamiya S, Yamamoto H, Kobayashi C, Izumi T, Ito K, Iwamoto Y, Tsuneyoshi M: Alterations of the RB1 gene in dedifferentiated liposarcoma. Mod Pathol; 2005 Nov;18(11):1461-70
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  • [Title] Alterations of the RB1 gene in dedifferentiated liposarcoma.
  • Dedifferentiated liposarcoma is a malignant adipocytic neoplasm containing a non-lipogenic sarcoma of variable histological grade that arises against the background of a pre-existing well-differentiated liposarcoma.
  • As a control, 11 undifferentiated high-grade pleomorphic sarcoma/pleomorphic malignant fibrous histiocytoma samples and 11 well-differentiated liposarcoma samples were also evaluated.
  • These results suggest that retinoblastoma protein has a major role to play in dedifferentiation and that a 'two-hit' mechanism is involved in the altered retinoblastoma protein expression in dedifferentiated liposarcoma.
  • [MeSH-major] Liposarcoma / genetics. Retinoblastoma Protein / genetics. Soft Tissue Neoplasms / genetics
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Base Sequence. DNA Methylation. Female. Humans. Loss of Heterozygosity. Male. Middle Aged. Polymerase Chain Reaction. Polymorphism, Single-Stranded Conformational. Promoter Regions, Genetic

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  • [Copyright] .Modern Pathology (2005) 18, 1454-1460. doi:10.1038/modpathol.3800444; published online 20 May 2005.
  • (PMID = 15933756.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Retinoblastoma Protein
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82. Hailu Y, Schneider J, T/Giorgis AT, Bayu S, Adamu Y: Liposarcoma presenting as a recurrent eyelid tumor. Ethiop Med J; 2008 Jul;46(3):281-5
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  • [Title] Liposarcoma presenting as a recurrent eyelid tumor.
  • Liposarcoma of the head and neck is rarely reported Orbital and eye lid involvement has been found to be extremely rare.
  • A 25 year old male patient from Harar presented with left eyelid mass of two years duration and diagnosed to have liposarcoma by incisional biopsy.
  • Despite the difficulty in obtaining wide surgical margins, the small tumor size at presentation and the apparent predominance of well-differentiated type means that the prognosis for orbital liposarcoma was generally good.
  • It is recommended to consider liposarcoma as a differential diagnosis of orbital mass lesions.
  • [MeSH-major] Eyelid Neoplasms / pathology. Liposarcoma / pathology. Orbital Neoplasms / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Humans. Male. Neoplasm Recurrence, Local. Treatment Outcome

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  • (PMID = 19271394.001).
  • [ISSN] 0014-1755
  • [Journal-full-title] Ethiopian medical journal
  • [ISO-abbreviation] Ethiop. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ethiopia
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83. Tang X, Guo W, Yang R, Yan T, Qu H: [Revision surgery for custom-made tumor prosthesis of knee joint]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2010 Jan;24(1):5-10
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  • The pathological diagnosis included 17 osteosarcomas, 11 giant cell tumors, 2 malignant fibrous histiocytomas, 1 chondrosarcoma, 1 synovial sarcoma, and 1 liposarcoma.
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Male. Middle Aged. Young Adult

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  • (PMID = 20135961.001).
  • [ISSN] 1002-1892
  • [Journal-full-title] Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
  • [ISO-abbreviation] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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84. Puhaindran ME, Steensma MR, Athanasian EA: Partial hand preservation for large soft tissue sarcomas of the hand. J Hand Surg Am; 2010 Feb;35(2):291-5
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  • Two patients had myxofibrosarcoma, 2 patients had synovial sarcoma, 2 patients had malignant fibrous histiocytoma, 1 patient had a malignant peripheral nerve sheath tumor, and 1 patient had a liposarcoma.
  • [MeSH-major] Hand / surgery. Limb Salvage / methods. Neoplasm Recurrence, Local / pathology. Sarcoma / diagnosis. Sarcoma / surgery. Soft Tissue Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Amputation / methods. Arm. Artificial Limbs. Child. Cohort Studies. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Staging. Prosthesis Fitting. Retrospective Studies. Risk Assessment. Survival Analysis. Treatment Outcome. Young Adult

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  • [Copyright] Copyright 2010 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20141899.001).
  • [ISSN] 1531-6564
  • [Journal-full-title] The Journal of hand surgery
  • [ISO-abbreviation] J Hand Surg Am
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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85. Torigoe T, Terakado A, Suehara Y, Kurosawa H, Yazawa Y, Takagi T: Bone versus soft-tissue sarcomas in the elderly. J Orthop Surg (Hong Kong); 2010 Apr;18(1):58-62
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  • Of the 14 soft-tissue sarcomas, 9 were malignant fibrous histiocytomas, 3 were myxofibrosarcomas, one was a liposarcoma and one an extraskeletal osteosarcoma; all were high grade except for 2 of the myxofibrosarcomas and the liposarcoma.
  • CONCLUSION: Survival rates tend to be lower in older patients with sarcomas, especially when the sarcoma is of bone and high grade.
  • [MeSH-major] Bone Neoplasms / mortality. Bone Neoplasms / pathology. Sarcoma / mortality. Sarcoma / pathology. Soft Tissue Neoplasms / mortality. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Age Factors. Aged. Aged, 80 and over. Child. Cohort Studies. Female. Humans. Male. Middle Aged. Neoplasm Staging. Retrospective Studies. Survival Analysis. Survival Rate. Young Adult

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  • (PMID = 20427836.001).
  • [ISSN] 2309-4990
  • [Journal-full-title] Journal of orthopaedic surgery (Hong Kong)
  • [ISO-abbreviation] J Orthop Surg (Hong Kong)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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86. Ferrari A, Casanova M: Specification on the definition of adult-type soft tissue sarcoma. J Clin Oncol; 2006 Aug 20;24(24):4042-3; author reply 4043-4
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  • [Title] Specification on the definition of adult-type soft tissue sarcoma.
  • [MeSH-major] Sarcoma / classification. Sarcoma / epidemiology. Terminology as Topic
  • [MeSH-minor] Adult. Age Distribution. Child. Clinical Trials as Topic. Europe / epidemiology. Humans. Liposarcoma / epidemiology. Medical Oncology. Middle Aged. Pediatrics. Sarcoma, Synovial / epidemiology

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  • [CommentOn] J Clin Oncol. 2005 Jun 20;23(18):4003-5 [15767649.001]
  • [CommentOn] J Clin Oncol. 2006 Apr 20;24(12):1958-9; author reply 1959-60 [16622276.001]
  • (PMID = 16921066.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] United States
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87. Baneth V, Raica M, Cîmpean AM: Assessment of angiogenesis in soft-tissue tumors. Rom J Morphol Embryol; 2005;46(4):323-7
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  • Microvessel density was higher especially in liposarcoma and malignant fibrous histiocytoma, and this finding suggests the application of the antiangiogenic therapy in soft tissue tumors in addition to conventional methods.
  • [MeSH-minor] Actins / analysis. Adolescent. Adult. Aged. Antigens, CD31 / analysis. Antigens, CD34 / analysis. Child. Female. Humans. Immunohistochemistry. Male. Microcirculation / pathology. Middle Aged. Tissue Embedding

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  • (PMID = 16688371.001).
  • [ISSN] 1220-0522
  • [Journal-full-title] Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
  • [ISO-abbreviation] Rom J Morphol Embryol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Romania
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, CD31; 0 / Antigens, CD34
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88. Driss M, Bacha D, Mrad K, Dhouib R, Sassi S, Abbes I, Chebbi A, Romdhane KB: [Retroperitoneal well-differentiated inflammatory liposarcoma]. Ann Pathol; 2007 Feb;27(1):35-7
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  • [Title] [Retroperitoneal well-differentiated inflammatory liposarcoma].
  • Inflammatory liposarcoma represents a rare variant of well-differentiated liposarcoma in which a chronic inflammatory infiltrate predominates simulating the appearance of malignant lymphoma and other nonneoplastic lesions.
  • [MeSH-major] Liposarcoma / pathology. Retroperitoneal Neoplasms / pathology
  • [MeSH-minor] Adult. Cell Differentiation. Diagnosis, Differential. Humans. Inflammation / pathology. Male. Tomography, X-Ray Computed

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  • (PMID = 17568358.001).
  • [ISSN] 0242-6498
  • [Journal-full-title] Annales de pathologie
  • [ISO-abbreviation] Ann Pathol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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89. Mridha AR, Sharma MC, Sarkar C, Suri V, Garg A, Suri A: Primary liposarcoma of the orbit: a report of two cases. Can J Ophthalmol; 2007 Jun;42(3):481-3
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  • [Title] Primary liposarcoma of the orbit: a report of two cases.
  • CASE REPORT: Only 21 cases of primary orbital liposarcoma have been previously published.

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  • (PMID = 17508053.001).
  • [ISSN] 0008-4182
  • [Journal-full-title] Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
  • [ISO-abbreviation] Can. J. Ophthalmol.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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90. Rakototiana A, Hunald F, Rakotovao M, Malinirina Ralahy F, Rakoto-Ratsimba HN, Rantomalala HY, Samison LH: [Paratesticular tumors seen in UTH Ravoahangy-Andrianavalona: epidemioclinical and therapeutical aspects]. Prog Urol; 2009 Oct;19(9):632-5
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  • Many histological types of tumors have been encountered: four cases of rhabdomyosarcoma (33.33%), one case of liposarcoma (8.33%), two cases of adenocarcinoma (16.66%), two cases of fibromas (16.66%) and three cases of leiomyoma (25%).
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Humans. Madagascar. Male. Middle Aged. Retrospective Studies. Young Adult

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  • (PMID = 19800554.001).
  • [ISSN] 1166-7087
  • [Journal-full-title] Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie
  • [ISO-abbreviation] Prog. Urol.
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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91. Yoshida K, Nakamurai E, Kawahara T, Inoue T, Sawazaki H, Kamba T, Yoshimura K, Takahashi T, Nishiyama H, Segawa T, Ito N, Kamoto T, Ogawa O, Fujii H, Shiomi T, Kotani Y, Mikami Y, Manabe T: [A case of myxoid liposarcoma in the right inguinal region: a case report]. Hinyokika Kiyo; 2006 Sep;52(9):727-31
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  • [Title] [A case of myxoid liposarcoma in the right inguinal region: a case report].
  • We report a case of myxoid liposarcoma developed in the right inguinal region.
  • A fatty mass 4.0 cm in diameter was demonstrated and the tumor was diagnosed as a liposarcoma preoperatively.
  • Histological examination revealed a myxoid liposarcoma and the existence of several daughter regions outside the pseudo-capsule.
  • [MeSH-major] Abdominal Neoplasms / surgery. Inguinal Canal. Liposarcoma, Myxoid / surgery
  • [MeSH-minor] Adult. Hernia, Inguinal / complications. Hernia, Inguinal / surgery. Humans. Magnetic Resonance Imaging. Male. Orchiectomy. Radiotherapy, Adjuvant. Tomography, X-Ray Computed

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  • (PMID = 17040061.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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92. Ji J, Hemminki K: Second primary malignancies among patients with soft tissue tumors in Sweden. Int J Cancer; 2006 Aug 15;119(4):909-14
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  • The overall risk of second malignancies decreased in the following order: fibrosarocma (1.63) > myxosarcoma (1.48) > leiomyosarcoma (1.44) > liposarcoma (1.21).
  • [MeSH-minor] Adult. Aged. Female. Follow-Up Studies. Humans. Male. Middle Aged. Sweden / epidemiology

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  • [Copyright] Copyright 2006 Wiley-Liss, Inc.
  • (PMID = 16557572.001).
  • [ISSN] 0020-7136
  • [Journal-full-title] International journal of cancer
  • [ISO-abbreviation] Int. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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93. De Padua M, Bhandari TP, Pingle J: Primary osteoliposarcoma of the bone. Indian J Pathol Microbiol; 2009 Jan-Mar;52(1):80-2
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  • A histopathological study of the excision specimen revealed areas of pleomorphic liposarcoma with numerous osteoblasts associated with areas of osteoid surrounded by neoplastic cells.
  • [MeSH-major] Bone Neoplasms / diagnosis. Bone Neoplasms / pathology. Liposarcoma / diagnosis. Liposarcoma / pathology. Osteosarcoma / diagnosis. Osteosarcoma / pathology
  • [MeSH-minor] Adult. Antineoplastic Agents / therapeutic use. Biopsy. Femur / pathology. Femur / radiography. Humans. Male

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  • (PMID = 19136790.001).
  • [ISSN] 0974-5130
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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94. Canter RJ, Qin LX, Ferrone CR, Maki RG, Singer S, Brennan MF: Why do patients with low-grade soft tissue sarcoma die? Ann Surg Oncol; 2008 Dec;15(12):3550-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Why do patients with low-grade soft tissue sarcoma die?
  • INTRODUCTION: The patterns of failure and mechanisms of sarcoma-specific death are poorly characterized among the minority of patients with low-grade soft tissue sarcoma (STS) who succumb to disease.
  • In 17 patients (9%), the mechanism of sarcoma-related death could not be verified.
  • For DOLR, site, size, positive margins, liposarcoma histology, and local recurrence (by definition) were significant factors.
  • Of DOLR, 80% were retroperitoneal, 68% were liposarcoma, and only 2% were extremity.
  • Conversely, of DODR, extremity (47%) and trunk (18%) were the most common sites, but histology was more variable [liposarcoma 35%, malignant fibrous histiocytoma (MFH) 20%, fibrosarcoma 12%, extraskeletal myxoid chondrosarcoma 10%].

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  • (PMID = 18830667.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA047179-09; United States / NCI NIH HHS / CA / P01 CA047179; United States / NCI NIH HHS / CA / P01 CA 047179; United States / NCI NIH HHS / CA / P01 CA047179-09
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS75337; NLM/ PMC2605207
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95. Bilici A, Uygun K, Altun E, Karci E, Gurbuz Y, Semih Dogan A: Primary peritoneal spindle cell sarcoma presented with massive ascites: a case report. J BUON; 2009 Oct-Dec;14(4):721-3
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  • [Title] Primary peritoneal spindle cell sarcoma presented with massive ascites: a case report.
  • Primary peritoneal sarcomas have been reported as leiomyosarcoma, liposarcoma and carcinosarcoma.
  • However, primary peritoneal spindle cell sarcoma has never been reported in the literature.
  • Herein, we report on a 38-year-old woman with massive ascites diagnosed as primary peritoneal spindle cell sarcoma.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Ascites / etiology. Peritoneal Neoplasms / complications. Sarcoma / complications. Soft Tissue Neoplasms / complications
  • [MeSH-minor] Adult. Doxorubicin / administration & dosage. Female. Humans. Ifosfamide / administration & dosage. Prognosis. Treatment Outcome

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  • (PMID = 20148470.001).
  • [ISSN] 1107-0625
  • [Journal-full-title] Journal of B.U.ON. : official journal of the Balkan Union of Oncology
  • [ISO-abbreviation] J BUON
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 80168379AG / Doxorubicin; UM20QQM95Y / Ifosfamide
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96. Jones RL, Fisher C, Al-Muderis O, Judson IR: Differential sensitivity of liposarcoma subtypes to chemotherapy. Eur J Cancer; 2005 Dec;41(18):2853-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Differential sensitivity of liposarcoma subtypes to chemotherapy.
  • Liposarcoma is one of the most common soft tissue sarcomas and has a number of different subtypes: well-differentiated; dedifferentiated; myxoid/round cell; and pleomorphic.
  • In this study, we have conducted a retrospective analysis of a prospectively maintained database of soft tissue sarcoma patients treated at the Royal Marsden Hospital.
  • Eighty-eight liposarcoma patients who received chemotherapy between August 1989 and June 2004 were identified.
  • A statistically significant higher response rate to first-line chemotherapy was observed in patients with myxoid liposarcoma compared to de- and well-differentiated tumours, 48% (95%CI; 28-69) and 11% (95%CI; 2-29), P = 0.005.
  • Similarly, those with myxoid liposarcoma had a significantly higher response rate compared to all other liposarcoma patients, 48% (95%CI; 28-69) and 18% (95%CI; 8-31).
  • This retrospective analysis suggests that myxoid liposarcoma is relatively chemosensitive in comparison to a combination of other liposarcomas, and in particular de- and well-differentiated tumours.
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Liposarcoma, Myxoid / drug therapy
  • [MeSH-minor] Adult. Aged. Chemotherapy, Adjuvant. Female. Humans. Male. Middle Aged. Neoplasm Metastasis. Prospective Studies. Retrospective Studies. Survival Analysis. Treatment Outcome

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  • (PMID = 16289617.001).
  • [ISSN] 0959-8049
  • [Journal-full-title] European journal of cancer (Oxford, England : 1990)
  • [ISO-abbreviation] Eur. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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97. Karateke A, Gurbuz A, Kabaca C, Alkan A, Kir G, Cetiner H: Uterine liposarcoma in a young woman: a case report. Int J Gynecol Cancer; 2005 Nov-Dec;15(6):1230-4
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  • [Title] Uterine liposarcoma in a young woman: a case report.
  • Liposarcoma of uterus is a very rare neoplasm encountered generally in the sixth or seventh decade of life.
  • We reported the eighth case of uterine liposarcoma with extension to broad ligament in a 23-year-old woman who presented with pelvic pain, dysuria, and rapidly enlarging pelvic mass.
  • The histopathologic examination of the specimen revealed liposarcoma.
  • Present case is the youngest patient with uterine liposarcoma and also the first case detected in reproductive period.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Liposarcoma / pathology. Uterine Cervical Neoplasms / pathology
  • [MeSH-minor] Adult. Doxorubicin / administration & dosage. Female. Gynecologic Surgical Procedures. Humans. Ifosfamide / administration & dosage. Mesna / administration & dosage. Protective Agents / administration & dosage


98. Makeieff M, Pelliccia P, Poizat F, Arnaud S, Rat F, Cupissol D, Guerrier B, Costes V: Laryngeal dedifferentiated liposarcoma. Eur Arch Otorhinolaryngol; 2010 Jun;267(6):991-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laryngeal dedifferentiated liposarcoma.
  • BACKGROUND: Soft tissue liposarcomas are quite common in the adult population, whereas liposarcoma of the larynx is exceedingly rare.
  • METHODS: We describe an exceptional case of liposarcoma of the posterior aspect of the left arytenoid in a 62-year-old woman who was treated with two endoscopic excisions and adjuvant radiotherapy (RT).
  • This is the 32nd case of laryngeal liposarcoma reported in the English literature.
  • However, recurrence of laryngeal liposarcoma is the principal risk, so extended follow-up is essential.
  • [MeSH-major] Cell Dedifferentiation / physiology. Hypopharyngeal Neoplasms / pathology. Laryngeal Neoplasms / pathology. Liposarcoma / pathology

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  • (PMID = 20383516.001).
  • [ISSN] 1434-4726
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
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  • [Language] eng
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99. Peiper M, Gerber PA, Engers R, Matuschek C, Budach W, Gripp S, Pape H, Orth K, Bölke E: Soft tissue sarcoma. Wien Klin Wochenschr; 2008;120(23-24):732
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Soft tissue sarcoma.
  • [MeSH-major] Liposarcoma, Myxoid / diagnosis. Shoulder. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Adult. Biopsy. Combined Modality Therapy. Humans. Male

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  • (PMID = 19122983.001).
  • [ISSN] 0043-5325
  • [Journal-full-title] Wiener klinische Wochenschrift
  • [ISO-abbreviation] Wien. Klin. Wochenschr.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Austria
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100. Tanimura S, Honma K, Aida Y: [Large malignant mesenchymoma of the left posterior mediastinum; report of a case]. Kyobu Geka; 2006 May;59(5):422-5
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  • The pathologic diagnosis was malignant mesenchymoma; well differentiated liposarcoma with osteocartilagenous differentiation.
  • [MeSH-minor] Adult. Female. Humans. Magnetic Resonance Imaging. Radiography, Thoracic. Thoracic Surgical Procedures. Tomography, X-Ray Computed

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  • (PMID = 16715896.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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