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1. Shahzadi S, Sharifi G, Andalibi R, Zali A, Ali-Asgari A: Management of cystic craniopharyngiomas with intracavitary irradiation with 32P. Arch Iran Med; 2008 Jan;11(1):30-4
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  • BACKGROUND: Cystic craniopharyngiomas are the most frequent intracranial neoplasm of nonglial origin in children.
  • METHODS: Patients with predominantly cystic craniopharyngiomas, who underwent stereotactic intracavitary irradiation, were followed for tumor response and complications.
  • The tumor response rate gained with 32P-labeled chromic phosphate was 73% (16 of 22 cysts).
  • [MeSH-major] Brachytherapy / methods. Craniopharyngioma / radiotherapy. Cysts / radiotherapy. Pituitary Neoplasms / radiotherapy
  • [MeSH-minor] Adolescent. Adult. Child. Female. Humans. Male. Phosphorus Radioisotopes / therapeutic use. Stereotaxic Techniques. Treatment Outcome

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  • (PMID = 18154420.001).
  • [ISSN] 1029-2977
  • [Journal-full-title] Archives of Iranian medicine
  • [ISO-abbreviation] Arch Iran Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Iran
  • [Chemical-registry-number] 0 / Phosphorus Radioisotopes
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2. Fortson JK, Rosenthal M, Lin JS, Lawrence G: Sigmoid sinus thrombosis associated with a parapharyngeal deep lobe parotid gland tumor causing seizure. Otolaryngol Head Neck Surg; 2010 Aug;143(2):313-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sigmoid sinus thrombosis associated with a parapharyngeal deep lobe parotid gland tumor causing seizure.
  • [MeSH-major] Parotid Neoplasms / complications. Seizures / etiology. Sinus Thrombosis, Intracranial / complications
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Magnetic Resonance Angiography. Male

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  • (PMID = 20647144.001).
  • [ISSN] 1097-6817
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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3. Barton VN, Donson AM, Kleinschmidt-DeMasters BK, Birks DK, Handler MH, Foreman NK: Unique molecular characteristics of pediatric myxopapillary ependymoma. Brain Pathol; 2010 May;20(3):560-70
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  • Clinical trial design requires a better understanding of tumor biology.
  • Unique molecular features of MEPN were investigated by using microarray technology to compare the gene expression of five pediatric MEPN to 24 pediatric intracranial ependymoma (EPN).
  • The upregulation of three genes of interest, homeobox B13 (HOXB13), neurofilament, light polypeptide (NEFL) and PDGFR alpha, was further studied by immunohistochemistry in a larger cohort that included adult MEPN and EPN specimens.
  • Protein expression in MEPN was compared to subependymoma, spinal EPN, intracranial EPN and normal fetal and adult ependyma.
  • Spinal and intracranial EPN generally expressed weak or focal staining.
  • [MeSH-major] Ependymoma / genetics. Ependymoma / metabolism. Nerve Tissue Proteins / genetics. Nerve Tissue Proteins / metabolism. Spinal Cord Neoplasms / genetics. Spinal Cord Neoplasms / metabolism
  • [MeSH-minor] Adolescent. Adult. Child. Cohort Studies. Female. Humans. Male. Retrospective Studies

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  • (PMID = 19793339.001).
  • [ISSN] 1750-3639
  • [Journal-full-title] Brain pathology (Zurich, Switzerland)
  • [ISO-abbreviation] Brain Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Nerve Tissue Proteins
  • [Other-IDs] NLM/ PMC2871180
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4. Wang ZY, Wu H, Huang Q: [Cranial schwannomas of jugular foramen]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2007 Jan;42(1):38-41
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  • According to classification, 5 cases were as intracranial type, 3 as jugular foramen type, 1 as neck extension type and the other 2 as combination type.
  • RESULTS: One-stage total tumor removal was accomplished in all the cases without any severe complications.
  • CSF leakage was occurred in 2 cases, no intracranial infection was found in all the cases.
  • Surgical approach selections depends on tumor classification on magnetic resonance imaging features.
  • [MeSH-major] Cranial Nerve Neoplasms. Neurilemmoma
  • [MeSH-minor] Adult. Aged. Female. Humans. Male. Middle Aged. Retrospective Studies. Skull

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  • (PMID = 17432355.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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5. Hayashi N, Kurimoto M, Nagai S, Sato H, Hori S, Endo S: Tentorial incision in a lateral-medial direction with minimal retraction of the temporal lobe in the subtemporal transtentorial approach to the middle tentorial incisural space. Minim Invasive Neurosurg; 2008 Dec;51(6):340-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Four patients, one with a superior cerebellar artery aneurysm, one with a metastatic tumor in the midbrain, one with a tentorial meningioma, and one with a tentorial schwannoma were treated with the present approach.
  • [MeSH-minor] Adult. Aged. Brain Stem Neoplasms / surgery. Female. Humans. Intracranial Aneurysm / surgery. Male. Mastoid / surgery. Meningeal Neoplasms / surgery. Meningioma / surgery. Middle Aged. Neurilemmoma / surgery. Retrospective Studies. Risk Factors

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  • (PMID = 19061145.001).
  • [ISSN] 0946-7211
  • [Journal-full-title] Minimally invasive neurosurgery : MIN
  • [ISO-abbreviation] Minim Invasive Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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6. Schick U, Bleyen J, Bani A, Hassler W: Management of meningiomas en plaque of the sphenoid wing. J Neurosurg; 2006 Feb;104(2):208-14
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  • The intracranial tumor was removed, and the dura mater and bone were reconstructed.
  • Subtotal resections were performed in 27 patients because there was intraorbital tumor (eight patients), tumor in the cavernous sinus (nine patients), tumor beyond the tentorial notch (three patients), tumor invading the superior orbital fissure (four patients), and tumor of the skull base (three patients).
  • Five patients underwent postoperative three-dimensional conformal radiotherapy, which resulted in stable tumor volume at follow up.
  • Tumor recurrence was identified in seven patients (10.4%) postoperatively (range of follow up 13-47 months).
  • CONCLUSIONS: The goal of surgery is complete tumor removal without morbidity.
  • An exact analysis of tumor growth and its involvement of different structures is mandatory before performing surgery.
  • [MeSH-major] Meningeal Neoplasms / pathology. Meningeal Neoplasms / surgery. Meningioma / pathology. Meningioma / surgery. Sphenoid Bone / pathology. Sphenoid Bone / surgery
  • [MeSH-minor] Adult. Aged. Craniotomy. Female. Humans. Male. Middle Aged. Morbidity. Neoplasm Invasiveness. Reconstructive Surgical Procedures. Retrospective Studies

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  • (PMID = 16509494.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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7. Kumar P, Jaiswal S, Agrawal T, Verma A, Datta NR: Malignant peripheral nerve sheath tumor of the occipital region: case report. Neurosurgery; 2007 Dec;61(6):E1334-5; discussion E1335
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant peripheral nerve sheath tumor of the occipital region: case report.
  • OBJECTIVE: A rare case of a malignant peripheral nerve sheath tumor of the occipital region is presented.
  • INTERVENTION: A small occipital craniectomy for total excision of the tumor was attempted.
  • However, as a result of intracranial extension to the transverse sinus, the tumor could not be completely excised.
  • CONCLUSION: An aggressive malignant peripheral nerve sheath tumor of an atypical site such as the scalp, in which complete surgery may not always be possible, could benefit from postoperative radiotherapy.
  • [MeSH-major] Brain Neoplasms. Nerve Sheath Neoplasms. Occipital Lobe / pathology
  • [MeSH-minor] Adult. Craniotomy / methods. Humans. Male. Tomography, X-Ray Computed / methods


8. Ganly I, Patel SG, Singh B, Kraus DH, Bridger PG, Cantu G, Cheesman A, De Sa G, Donald P, Fliss DM, Gullane P, Janecka I, Kamata SE, Kowalski LP, Levine PA, Medina Dos Santos LR, Pradhan S, Schramm V, Snyderman C, Wei WI, Shah JP: Craniofacial resection for malignant paranasal sinus tumors: Report of an International Collaborative Study. Head Neck; 2005 Jul;27(7):575-84
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This International Collaborative study examines a large cohort of patients accumulated from multiple institutions experienced in craniofacial surgery, with the aim of reporting benchmark figures for outcomes and identifying patient-related and tumor-related predictors of prognosis after craniofacial resection (CFR).
  • Statistical analyses for outcomes were performed in relation to patient characteristics, tumor characteristics, including histologic findings and extent of disease, surgical resection margins, prior radiation, and prior chemotherapy to determine predictive factors.
  • The status of surgical margins, histologic findings of the primary tumor, and intracranial extent were independent predictors of overall, disease-specific, and recurrence-free survival on multivariate analysis.
  • The status of surgical margins, histologic findings of the primary tumor, and intracranial extent are independent predictors of outcome.
  • [MeSH-major] Adenocarcinoma / surgery. Carcinoma, Squamous Cell / surgery. Paranasal Sinus Neoplasms / surgery. Skull / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Cohort Studies. Female. Follow-Up Studies. Humans. International Cooperation. Male. Middle Aged. Multivariate Analysis. Neoplasm Invasiveness. Neoplasm Recurrence, Local. Postoperative Complications. Skull Base / pathology. Skull Base / surgery. Survival Rate. Treatment Outcome

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  • (PMID = 15825201.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
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9. Yang LS, Huang FP, Zheng K, Zhang HS, Zhou X, Bao XH, Zheng JJ, Chang C, Zhou LF: Factors affecting prognosis of patients with intracranial anaplastic oligodendrogliomas: a single institutional review of 70 patients. J Neurooncol; 2010 Oct;100(1):113-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Factors affecting prognosis of patients with intracranial anaplastic oligodendrogliomas: a single institutional review of 70 patients.
  • Anaplastic oligodendroglioma (AO) is an uncommon intracranial tumor and prognosis is poor.
  • [MeSH-major] Brain Neoplasms / diagnosis. Oligodendroglioma / diagnosis
  • [MeSH-minor] Adolescent. Adult. Age Factors. Aged. Child. Drug Therapy. Female. Humans. Karnofsky Performance Status. Longitudinal Studies. Magnetic Resonance Imaging / methods. Male. Middle Aged. Prognosis. Radiotherapy. Retrospective Studies. Tomography Scanners, X-Ray Computed. Young Adult

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  • (PMID = 20195700.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
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10. Hemm S, Rigau V, Chevalier J, Picot MC, Bauchet L, El Fertit H, Rodriguez MA, Cif L, Vayssière N, Zanca M, Baldet P, Segnarbieux F, Coubes P: Stereotactic coregistration of 201Tl SPECT and MRI applied to brain tumor biopsies. J Nucl Med; 2005 Jul;46(7):1151-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Stereotactic coregistration of 201Tl SPECT and MRI applied to brain tumor biopsies.
  • The aim of the present study was to determine the clinical feasibility of integration of stereotactic SPECT (sSPECT) with 201Tl in the stereotactic MRI (sMRI)-based planning of brain tumor biopsy.
  • METHODS: Ten patients underwent combined 201Tl SPECT- and MRI-guided stereotactic biopsy of intracranial lesions according to a previously described technique.
  • An extensive histologic diagnosis (tumor grade, mitotic index [MI], and Ki67 index) and the 201Tl index were obtained for all samples and compared statistically.
  • Ki67 index, MI, and tumor grade correlated significantly.
  • A trend to significance existed between tumor grade and 201Tl index (R = 0.31; P = 0.06).
  • In 4 of the 10 patients, a variation in tumor grade could be observed along the trajectory.
  • CONCLUSION: These results support the view that 201Tl SPECT may contribute to the successful management of brain tumor patients requiring stereotactic biopsy, without causing a significant increase in discomfort or morbidity.
  • [MeSH-major] Biopsy, Needle / methods. Brain Neoplasms / pathology. Image Interpretation, Computer-Assisted / methods. Magnetic Resonance Imaging / methods. Stereotaxic Techniques. Subtraction Technique. Thallium. Tomography, Emission-Computed, Single-Photon / methods
  • [MeSH-minor] Adult. Aged. Algorithms. Female. Humans. Imaging, Three-Dimensional / methods. Male. Middle Aged. Radiopharmaceuticals. Surgery, Computer-Assisted / methods

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  • Hazardous Substances Data Bank. THALLIUM, ELEMENTAL .
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  • (PMID = 16000284.001).
  • [ISSN] 0161-5505
  • [Journal-full-title] Journal of nuclear medicine : official publication, Society of Nuclear Medicine
  • [ISO-abbreviation] J. Nucl. Med.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 7791-12-0 / thallium chloride; AD84R52XLF / Thallium
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11. Wu WX, Yu SZ, Sun CY, Wang Q, Jin SM, An TL: [Detection of chromosomal imbalance in ependymoma by comparative genomic hybridization]. Zhonghua Bing Li Xue Za Zhi; 2009 Mar;38(3):148-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To investigate genomic DNA imbalances in ependymomas (EDMs) and their correlations with the tumor histological types, grades, locations, patients' gender and age.
  • Chromosomal +1q and +7p happened predominantly in intracranial EDMs with an averagely onset age of <or= 30 years, and +7 was only detected in spinal EDMs of patients over 30 years old, the differences were statistically significant (P < 0.05).
  • CONCLUSIONS: The frequencies of chromosomal imbalances in EDMs decrease as the tumor grade increases.
  • Characteristic chromosomal imbalances in each subtype may play an important role in determination of histological phenotypes and tumor grades.
  • [MeSH-major] Brain Neoplasms / genetics. Chromosome Aberrations. Ependymoma / genetics. Spinal Cord Neoplasms / genetics
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Comparative Genomic Hybridization. DNA, Neoplasm / genetics. Female. Humans. Male. Middle Aged. Young Adult

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  • (PMID = 19575847.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / DNA, Neoplasm
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12. Miyazawa T, Aida S, Shima K: Hemorrhagic cerebellar anaplastic glioma appearing 12 years after prophylactic cranial radiotherapy for acute lymphocytic leukemia. Neurol Med Chir (Tokyo); 2008 Mar;48(3):126-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A radiation-induced cerebellar glioma is extremely rare, and the etiology of such a tumor is unknown.
  • [MeSH-major] Cerebellar Neoplasms / etiology. Glioma / etiology. Intracranial Hemorrhages / etiology. Neoplasms, Radiation-Induced / etiology. Neoplasms, Second Primary / etiology. Precursor Cell Lymphoblastic Leukemia-Lymphoma / radiotherapy
  • [MeSH-minor] Adult. Anaplasia / etiology. Anaplasia / pathology. Humans. Male. Radiotherapy / adverse effects. Time Factors

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  • (PMID = 18362460.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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13. Simon SL, Moonis G, Judkins AR, Scobie J, Burnett MG, Riina HA, Judy KD: Intracranial capillary hemangioma: case report and review of the literature. Surg Neurol; 2005 Aug;64(2):154-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intracranial capillary hemangioma: case report and review of the literature.
  • The authors present an exceedingly rare case of an intracranial capillary hemangioma arising in an adult.
  • The patient underwent a resection of her tumor, which was diagnosed as a capillary hemangioma by histopathologic examination.
  • The patient required 2 further resections after the lesion exhibited a rapid regrowth from residual tumor in the left transverse sinus.
  • CONCLUSIONS: Intracranial capillary hemangiomas are exceedingly rare entities, with a capability for rapid growth.
  • [MeSH-major] Brain Neoplasms / surgery. Hemangioma, Capillary / surgery. Neoplasm Recurrence, Local / surgery. Pregnancy Complications, Neoplastic / surgery
  • [MeSH-minor] Adult. Female. Humans. Pregnancy. Treatment Outcome


14. Chernov MF, Hayashi M, Izawa M, Usukura M, Yoshida S, Ono Y, Muragaki Y, Kubo O, Hori T, Takakura K: Multivoxel proton MRS for differentiation of radiation-induced necrosis and tumor recurrence after gamma knife radiosurgery for brain metastases. Brain Tumor Pathol; 2006 Apr;23(1):19-27
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  • [Title] Multivoxel proton MRS for differentiation of radiation-induced necrosis and tumor recurrence after gamma knife radiosurgery for brain metastases.
  • Multivoxel proton magnetic resonance spectroscopy (MRS) was used for differentiation of radiation-induced necrosis and tumor recurrence after gamma knife radiosurgery for intracranial metastases in 33 consecutive cases.
  • Metabolic imaging defined four types of lesions: pure tumor recurrence (11 cases), partial tumor recurrence (11 cases), radiation-induced tumor necrosis (10 cases), and radiation-induced necrosis of the peritumoral brain (1 case).
  • In 1 patient, radiation-induced tumor necrosis was diagnosed 9 months after radiosurgery; however, partial tumor recurrence was identified 6 months later.
  • In conclusion, multivoxel proton MRS is an effective diagnostic modality for identification of radiation-induced necrosis and tumor recurrence that can be used for monitoring of metabolic changes in intracranial neoplasms after radiosurgical treatment.
  • It can be also helpful for differentiation of radiation-induced necrosis of the tumor and that of the peritumoral brain, which may have important clinical and medicolegal implications.
  • [MeSH-major] Brain Neoplasms / pathology. Brain Neoplasms / secondary. Necrosis / pathology. Neoplasm Recurrence, Local / pathology. Radiation Injuries / pathology. Radiosurgery / adverse effects
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Brain Chemistry. Diagnosis, Differential. Disease Progression. Female. Fluorodeoxyglucose F18. Humans. Image Processing, Computer-Assisted. Magnetic Resonance Spectroscopy. Male. Middle Aged. Positron-Emission Tomography. Radiopharmaceuticals. Treatment Outcome

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  • (PMID = 18095115.001).
  • [ISSN] 1433-7398
  • [Journal-full-title] Brain tumor pathology
  • [ISO-abbreviation] Brain Tumor Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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15. Shim KW, Kim TG, Suh CO, Cho JH, Yoo CJ, Choi JU, Kim JH, Kim DS: Treatment failure in intracranial primary germinomas. Childs Nerv Syst; 2007 Oct;23(10):1155-61
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  • [Title] Treatment failure in intracranial primary germinomas.
  • OBJECT: A radiation dose of 40-50 Gy is able to produce a cure rate of more than 90% in intracranial pure germinoma.
  • Tumor recurrence was closely related to the volume of radiation but not to the dose of radiation.
  • If the tumor bed and craniospinal axis were fully covered, the radiation dose might be reduced.
  • Chemotherapy alone showed earlier recurrence and a higher tumor recurrence rate.
  • [MeSH-major] Brain Neoplasms / therapy. Germinoma / therapy
  • [MeSH-minor] Adolescent. Adult. Antineoplastic Agents / therapeutic use. Child. Child, Preschool. Combined Modality Therapy. Dose-Response Relationship, Radiation. Female. Humans. Infant. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Recurrence, Local. Neurosurgical Procedures. Survival Analysis. Tomography, X-Ray Computed. Treatment Failure

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  • (PMID = 17610071.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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16. Matsumoto J, Kochi M, Morioka M, Nakamura H, Makino K, Hamada J, Kuratsu J, Ushio Y: A long-term ventricular drainage for patients with germ cell tumors or medulloblastoma. Surg Neurol; 2006 Jan;65(1):74-80; discussion 80
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  • BACKGROUND: Hydrocephalus associated with intracranial germ cell tumors or disseminated medulloblastoma has been treated with ventriculoperitoneal shunt.
  • Of 96 patients, 59 (germ cell tumor, 31; medulloblastoma, 28) had hydrocephalus and 13 needed long-term cerebrospinal fluid drainage to manage the obstructive hydrocephalus due to persistent tumor or communicating hydrocephalus due to dissemination.
  • [MeSH-major] Brain Neoplasms / complications. Hydrocephalus / etiology. Hydrocephalus / surgery. Medulloblastoma / complications. Neoplasms, Germ Cell and Embryonal / complications. Ventriculoperitoneal Shunt
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Female. Humans. Incidence. Infant. Infection / epidemiology. Male. Postoperative Complications / epidemiology. Retrospective Studies. Time Factors


17. Welzel G, Fleckenstein K, Mai SK, Hermann B, Kraus-Tiefenbacher U, Wenz F: Acute neurocognitive impairment during cranial radiation therapy in patients with intracranial tumors. Strahlenther Onkol; 2008 Dec;184(12):647-54
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  • [Title] Acute neurocognitive impairment during cranial radiation therapy in patients with intracranial tumors.
  • We assessed patients with and without intracranial tumors to distinguish between direct and indirect radiation effects on brain tissue.
  • Sixty-four patients received RT to the brain (55 with, 9 without intracranial tumor).
  • RESULTS: Patients with intracranial tumor demonstrated attention (19-38th percentile) and verbal memory scores (34-46th percentile) below the population average at baseline.
  • The average Verbal Memory score was significantly different between patients with intracranial tumor and controls both at baseline (38th vs. 58th percentile) and after irradiation (27th vs. 52th percentile).
  • Radiation dose-related deficits were seen for working memory performance in patients with intracranial tumor.
  • Patients with intracranial tumor show a deterioration of almost all memory functions with a dose-dependent impairment in working memory.
  • [MeSH-major] Attention / radiation effects. Brain / radiation effects. Brain Neoplasms / radiotherapy. Cognition / radiation effects. Cranial Irradiation / adverse effects. Memory / radiation effects. Radiotherapy / adverse effects
  • [MeSH-minor] Adult. Aged. Brain Edema / complications. Data Interpretation, Statistical. Female. Humans. Male. Middle Aged. Neuropsychological Tests. Radiotherapy Dosage

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  • (PMID = 19107345.001).
  • [ISSN] 0179-7158
  • [Journal-full-title] Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
  • [ISO-abbreviation] Strahlenther Onkol
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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18. Kanamori M, Kumabe T, Saito R, Yamashita Y, Sonoda Y, Tominaga T: [The safety of combination chemotherapy with ifosfamide, cisplatin, and etoposide (ICE): single-institution retrospective review of 108 cases]. No Shinkei Geka; 2010 Nov;38(11):997-1005
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  • PURPOSE: The adverse effects of combination chemotherapy of ifosfamide, cisplatin, and etoposide (ICE) were evaluated in the treatment of various intracranial brain tumors.
  • The histological diagnosis was newly diagnosed or recurrent germ cell tumor in 45 cases, medulloblastoma in 19, primitive neuroectodermal tumor (PNET) in 7, anaplastic ependymoma in 6, recurrent glioblastoma in 13, and others in 18 cases.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / adverse effects. Brain Neoplasms / drug therapy
  • [MeSH-minor] Adolescent. Adult. Antineoplastic Agents / administration & dosage. Antineoplastic Agents / adverse effects. Antineoplastic Agents, Alkylating / administration & dosage. Antineoplastic Agents, Alkylating / adverse effects. Antineoplastic Agents, Phytogenic / administration & dosage. Antineoplastic Agents, Phytogenic / adverse effects. Child. Child, Preschool. Cisplatin / administration & dosage. Cisplatin / adverse effects. Ependymoma / drug therapy. Etoposide / administration & dosage. Etoposide / adverse effects. Female. Glioblastoma / drug therapy. Hematologic Diseases / chemically induced. Humans. Ifosfamide / administration & dosage. Ifosfamide / adverse effects. Infant. Male. Medulloblastoma / drug therapy. Middle Aged. Neoplasms, Germ Cell and Embryonal / drug therapy. Neuroectodermal Tumors, Primitive / drug therapy. Retrospective Studies

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  • (PMID = 21081811.001).
  • [ISSN] 0301-2603
  • [Journal-full-title] No shinkei geka. Neurological surgery
  • [ISO-abbreviation] No Shinkei Geka
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Antineoplastic Agents, Alkylating; 0 / Antineoplastic Agents, Phytogenic; 6PLQ3CP4P3 / Etoposide; Q20Q21Q62J / Cisplatin; UM20QQM95Y / Ifosfamide
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19. Tanioka D, Abe T, Kunii N, Izumiyama H: [A case of a hemorrhagic non-functioning pituitary adenoma presenting with abducens nerve palsy]. No Shinkei Geka; 2005 May;33(5):473-9
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  • The etiology of isolated abducens nerve palsy by a pituitary tumor is discussed.
  • The tumor was totally resected via the transnasal route.
  • It was supposed that the isolated abducens nerve palsy was caused by the direct compression of abducens nerve in the cavernous sinus by the extension of a pituitary tumor and hematoma.
  • [MeSH-major] Abducens Nerve Diseases / etiology. Adenoma / complications. Intracranial Hemorrhages / complications. Pituitary Neoplasms / complications
  • [MeSH-minor] Adult. Humans. Hypophysectomy / methods. Magnetic Resonance Imaging. Male. Pituitary Apoplexy / etiology

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  • (PMID = 15912767.001).
  • [ISSN] 0301-2603
  • [Journal-full-title] No shinkei geka. Neurological surgery
  • [ISO-abbreviation] No Shinkei Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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20. Zhang L, Zhang M, Zhang J, Luo L, Xu Z, Li G, Tian Y, Wang Y, Wu Z, Wang Z: Myxoma of the cranial base. Surg Neurol; 2007;68 Suppl 2:S22-8
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  • BACKGROUND: In 1871, Virchow described a type of tumor, which he named myxoma, which had a similar appearance to mucinous tissue of the umbilical cord.
  • From an etiologic perspective, intracranial myxoma is divided into either primary or secondary induction.
  • The majority of primary myxomas are found at the skull base, whereas secondary intracranial myxomas are mainly caused by metastatic tumor emboli from the cardiac myxomas; the emboli may also transfer to cerebrovascular endothelium to cause fusiform aneurysm.
  • Surgical approaches were variable and selected according to tumor locations.
  • During the period of follow-up, remission was gained in 6 cases and tumor recurrence in 4 patients; 1 patient died.
  • [MeSH-major] Myxoma / surgery. Neurosurgical Procedures. Skull Base Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Cohort Studies. Disease-Free Survival. Female. Humans. Male. Middle Aged. Radiotherapy, Adjuvant. Retrospective Studies. Treatment Outcome

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  • (PMID = 18037039.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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21. Cho JM, Ahn JY, Kim SH, Lee KS, Chang JH: An endodermal cyst mimicking an intra-axial tumor in the medulla oblongata. Childs Nerv Syst; 2010 Jun;26(6):853-6
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  • [Title] An endodermal cyst mimicking an intra-axial tumor in the medulla oblongata.
  • Endodermal cysts are rarely intracranial, but when this occurs, the cysts are frequently located in the posterior fossa with the most common locations being anterior to the brainstem and within the fourth ventricle.
  • [MeSH-major] Brain Diseases / diagnosis. Brain Neoplasms / diagnosis. Cysts / diagnosis. Medulla Oblongata
  • [MeSH-minor] Diagnosis, Differential. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Treatment Outcome. Young Adult

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  • [CommentIn] Childs Nerv Syst. 2011 Jun;27(6):861-2; author reply 863 [21503756.001]
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  • (PMID = 20217097.001).
  • [ISSN] 1433-0350
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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22. Xia CF, Zhang Y, Zhang Y, Boado RJ, Pardridge WM: Intravenous siRNA of brain cancer with receptor targeting and avidin-biotin technology. Pharm Res; 2007 Dec;24(12):2309-16
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  • RESULTS: Rat glial cells (C6 or RG-2) were permanently transfected with the luciferase gene, and implanted in the brain of adult rats.
  • The intravenous administration of the siRNA caused a 69-81% decrease in luciferase gene expression in the intracranial brain cancer in vivo.
  • [MeSH-major] Antibodies, Monoclonal / metabolism. Biotin / metabolism. Brain Neoplasms / therapy. Gene Transfer Techniques. Genetic Therapy / methods. RNA Interference. RNA, Small Interfering / metabolism. Receptors, Transferrin / immunology. Streptavidin / metabolism
  • [MeSH-minor] Animals. Biotinylation. Blood-Brain Barrier / metabolism. Cell Line, Tumor. Genes, Reporter. Humans. Luciferases / genetics. Male. Rats. Rats, Inbred F344. Receptor, Insulin / immunology. Time Factors. Transfection

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  • (PMID = 17926121.001).
  • [ISSN] 0724-8741
  • [Journal-full-title] Pharmaceutical research
  • [ISO-abbreviation] Pharm. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / RNA, Small Interfering; 0 / Receptors, Transferrin; 6SO6U10H04 / Biotin; 9013-20-1 / Streptavidin; EC 1.13.12.- / Luciferases; EC 2.7.10.1 / Receptor, Insulin
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23. Giesel FL, Mehndiratta A, Risse F, Rius M, Zechmann CM, von Tengg-Kobligk H, Gerigk L, Kauczor HU, Politi M, Essig M, Griffiths PD, Wilkinson ID: Intraindividual comparison between gadopentetate dimeglumine and gadobutrol for magnetic resonance perfusion in normal brain and intracranial tumors at 3 Tesla. Acta Radiol; 2009 Jun;50(5):521-30
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  • [Title] Intraindividual comparison between gadopentetate dimeglumine and gadobutrol for magnetic resonance perfusion in normal brain and intracranial tumors at 3 Tesla.
  • PURPOSE: To investigate possible intraindividual differences of high- versus low-molar contrast agents on PWI at 3T in patients with intracranial space-occupying lesions.
  • On each occasion, an exogenous contrast-based, T2*-weighted, gradient-recalled echo-planar imaging (EPI) technique was used to determine the intracranial perfusion characteristics using one of two intravenous contrast agents: either 5 ml of 1.0 M gadobutrol or 10 ml of 0.5 M gadopentetate dimeglumine.
  • The ratio of C(max) between the whole tumor and whole normal side hemisphere was higher in five out of the six intraaxial tumor cases.
  • A significantly higher ratio (Delta C(max)/C(max)) in the difference between C(max) of gray and white matter (from hemisphere without brain lesion) compared to C(max) for the hemisphere containing the neoplasm (hemisphere with brain lesion) was demonstrated for gadobutrol in intraaxial tumors (P<0.05).
  • CONCLUSION: Higher-concentration 1.0 M gadobutrol can offer advantages over standard 0.5 M gadopentetate dimeglumine, particularly with respect to delineation between gray and white matter and for the demarcation of highly vascularized tumor tissue on brain PWI performed at 3T.
  • [MeSH-major] Brain Neoplasms / diagnosis. Gadolinium DTPA. Image Enhancement / methods. Lymphoma, Non-Hodgkin / diagnosis. Magnetic Resonance Imaging / methods. Neoplasms, Nerve Tissue / diagnosis. Organometallic Compounds
  • [MeSH-minor] Adult. Aged. Brain / blood supply. Brain / pathology. Brain Mapping / methods. Cerebrovascular Circulation. Contrast Media. Humans. Image Processing, Computer-Assisted / methods. Middle Aged

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  • (PMID = 19337867.001).
  • [ISSN] 1600-0455
  • [Journal-full-title] Acta radiologica (Stockholm, Sweden : 1987)
  • [ISO-abbreviation] Acta Radiol
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article
  • [Publication-country] Sweden
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Organometallic Compounds; 1BJ477IO2L / gadobutrol; K2I13DR72L / Gadolinium DTPA
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24. Fainstein Day P, Frohman L, Garcia Rivello H, Reubi JC, Sevlever G, Glerean M, Fernandez Gianotti T, Pietrani M, Rabadan A, Racioppi S, Bidlingmaier M: Ectopic growth hormone-releasing hormone secretion by a metastatic bronchial carcinoid tumor: a case with a non hypophysial intracranial tumor that shrank during long acting octreotide treatment. Pituitary; 2007;10(3):311-9
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  • [Title] Ectopic growth hormone-releasing hormone secretion by a metastatic bronchial carcinoid tumor: a case with a non hypophysial intracranial tumor that shrank during long acting octreotide treatment.
  • Although clinical improvement is common after treatment with somatostatin (SMS) analogs, the biochemical response and tumor size of the growth hormone-releasing hormone (GHRH)-producing tumor and its metastases are less predictable.
  • He had undergone lung surgery in 1987 for a "benign" carcinoid tumor.
  • Methods Measurement of circulating GHRH levels by fluorescence immunoassay levels and immunohistochemical study of the primary lung tumor and metastatic tissue with anti-GHRH and anti-somatostatin receptor type 2 (sst2A) antibodies.
  • [MeSH-major] Antineoplastic Agents, Hormonal / therapeutic use. Bronchial Neoplasms / secondary. Bronchial Neoplasms / secretion. Carcinoid Tumor / secondary. Carcinoid Tumor / secretion. Growth Hormone-Releasing Hormone / secretion. Hormones, Ectopic / secretion. Human Growth Hormone / secretion. Octreotide / therapeutic use
  • [MeSH-minor] Acromegaly / etiology. Adult. Blood Glucose / metabolism. Cerebellopontine Angle / pathology. Humans. Liver / pathology. Magnetic Resonance Imaging. Male. Positron-Emission Tomography. Radiopharmaceuticals. Receptors, Somatostatin / metabolism. Whole Body Imaging

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  • (PMID = 17373589.001).
  • [ISSN] 1386-341X
  • [Journal-full-title] Pituitary
  • [ISO-abbreviation] Pituitary
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Hormonal; 0 / Blood Glucose; 0 / Hormones, Ectopic; 0 / Radiopharmaceuticals; 0 / Receptors, Somatostatin; 12629-01-5 / Human Growth Hormone; 9034-39-3 / Growth Hormone-Releasing Hormone; RWM8CCW8GP / Octreotide
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25. Shu HK, Sall WF, Maity A, Tochner ZA, Janss AJ, Belasco JB, Rorke-Adams LB, Phillips PC, Sutton LN, Fisher MJ: Childhood intracranial ependymoma: twenty-year experience from a single institution. Cancer; 2007 Jul 15;110(2):432-41
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  • [Title] Childhood intracranial ependymoma: twenty-year experience from a single institution.
  • METHODS: Medical records were reviews of patients with intracranial ependymoma who received their initial treatment at the Children's Hospital of Philadelphia (CHOP)/Hospital of the University of Pennsylvania (HUP) between January 1980 and December 2000.
  • CONCLUSIONS: In this study of patients with pediatric intracranial ependymoma, OS and PFS rates were concordant with the rates published in other modern series.
  • Tumor extension to the cervical spine was identified as a predictor for failure outside of the primary site.
  • [MeSH-major] Brain Neoplasms / pathology. Ependymoma / pathology
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Female. Humans. Infant. Male. Prognosis. Survival Analysis. Treatment Outcome


26. Dean NR, White HN, Carter DS, Desmond RA, Carroll WR, McGrew BM, Rosenthal EL: Outcomes following temporal bone resection. Laryngoscope; 2010 Aug;120(8):1516-22
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  • Tumor characteristics, defect reconstruction, and postoperative course were assessed.
  • Thirty-nine patients had perineural invasion (60%) and required facial nerve resection; 16 (25%) had intracranial extension.

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  • (PMID = 20641083.001).
  • [ISSN] 1531-4995
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / 2T32 CA091078-06; United States / NCI NIH HHS / CA / T32 CA091078; United States / NCI NIH HHS / CA / R01 CA142637; United States / NCI NIH HHS / CA / K08 CA102154; United States / NCI NIH HHS / CA / K08CA102154
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS556293; NLM/ PMC3951338
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27. Wang T, Wang X, Li M, Xu A, Chen Y: [Surgical approaches of anterior skull base tumors]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2007 Jan;21(2):50-1
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  • RESULT: Of the 27 malignant cases the 3 and 5-year survival rates were 81.9% (22/27) and 62.9% (17/27) respectively, and one tumor free case living well more than 9 years.
  • There were no recurrence in 10 cases with benign tumor.
  • CONCLUSIONS: Various craniofacial approaches except lateral rhinotomy provide directly satisfactory tumor exposure and facilitate enbloc resection of the naso paranasal sinus tumor with intracranial extension.
  • Partial or total maxillary swing combined with naso pyramid translocation is good for tumor involving the skull base without intracranial invasion.
  • The fronto-nasal pyramid translocation is good for removal of the upper part of nasal tumor with intracranial extension on well developed frontal sinus.
  • The fronto orbital approach is proper for removal of fronto-sphenoid tumor and midface degloving may be used in selected cases.
  • [MeSH-major] Craniotomy / methods. Skull Base / surgery. Skull Base Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Frontal Bone / surgery. Humans. Male. Middle Aged. Nose / surgery. Young Adult

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  • (PMID = 17438840.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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28. Kasliwal MK, Suri A, Rishi A, Suri V, Sharma BS, Sarkar C: Symptomatic bilateral cerebellar mass lesions: an unusual presentation of intracranial xanthogranuloma. J Clin Neurosci; 2008 Dec;15(12):1401-4
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  • [Title] Symptomatic bilateral cerebellar mass lesions: an unusual presentation of intracranial xanthogranuloma.
  • Although the lateral ventricle is the most frequent intracranial site involved, most symptomatic cases occur in the choroid plexus, involving the third ventricle.
  • The role of histopathology cannot be overemphasized in the diagnosis of this rare lesion and long-term follow-up is advised in cases managed conservatively owing to the propensity of this tumor to grow over time.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Granuloma / pathology. Xanthomatosis / pathology
  • [MeSH-minor] Adult. Humans. Magnetic Resonance Imaging / methods. Male. Tomography, X-Ray Computed / methods

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  • (PMID = 18952438.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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29. Kikuchi Y, Sasaki T, Matsumoto M, Oikawa T, Itakura T, Kodama N: Optic nerve evoked potentials elicited by electrical stimulation. Neurol Med Chir (Tokyo); 2005 Jul;45(7):349-55; discussion 354-5
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  • In the remaining patient, the ONEP, recorded only after tumor removal because the optic nerve was stretched and extremely thin, was remarkably small and the patient developed unilateral blindness postoperatively.
  • [MeSH-major] Brain Neoplasms / surgery. Evoked Potentials. Intracranial Aneurysm / surgery. Monitoring, Intraoperative / methods. Optic Nerve / physiopathology. Vision, Ocular
  • [MeSH-minor] Adult. Aged. Animals. Dogs. Electric Stimulation. Humans. Middle Aged

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  • (PMID = 16041180.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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30. Ogden AT, Horgan D, Waziri A, Anderson D, Louca J, McKhann GM, Sisti MB, Parsa AT, Bruce JN: Defective receptor expression and dendritic cell differentiation of monocytes in glioblastomas. Neurosurgery; 2006 Oct;59(4):902-9; discussion 909-10
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  • This study seeks to develop understanding of the phenotypic changes that occur in circulating monocytes of patients with intracranial cancer and to assess the ability of these cells to differentiate into mature dendritic cells.
  • METHODS: Monocyte expression levels of HLA-ABC, HLA-DR, CD86, ICAM-1, TNFRII, and GMCSFR were compared between three cohorts: patients with intracranial glioblastoma (n = 15), patients with intracranial metastases (n = 9), and a group of healthy controls (n = 10).
  • RESULTS: Comprehensive analysis of monocyte receptor expression demonstrated significantly reduced HLA-ABC, HLA-DR, CD86, ICAM-1, and TNFRII in patients with glioblastoma but not in patients with intracranial metastases compared with a group of healthy controls.
  • GMCSFR expression was significantly reduced in both patients with glioblastoma and intracranial metastases.
  • [MeSH-major] Brain Neoplasms / metabolism. Brain Neoplasms / pathology. Dendritic Cells / pathology. Glioblastoma / metabolism. Glioblastoma / pathology. Monocytes / metabolism. Monocytes / pathology. Receptors, Cell Surface / metabolism
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Antigens, CD / metabolism. Antigens, CD86 / metabolism. Cell Differentiation. Cells, Cultured. Cohort Studies. Female. HLA Antigens / metabolism. Humans. Immunoglobulins / metabolism. Intercellular Adhesion Molecule-1 / metabolism. Male. Membrane Glycoproteins / metabolism. Middle Aged. Receptors, Tumor Necrosis Factor, Type II / metabolism

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  • (PMID = 17038955.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD86; 0 / CD83 antigen; 0 / HLA Antigens; 0 / Immunoglobulins; 0 / Membrane Glycoproteins; 0 / Receptors, Cell Surface; 0 / Receptors, Tumor Necrosis Factor, Type II; 126547-89-5 / Intercellular Adhesion Molecule-1
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31. Kano H, Niranjan A, Kondziolka D, Flickinger JC, Lunsford LD: Outcome predictors for intracranial ependymoma radiosurgery. Neurosurgery; 2009 Feb;64(2):279-87; discussion 287-8
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  • [Title] Outcome predictors for intracranial ependymoma radiosurgery.
  • OBJECTIVE: To develop outcome predictors after stereotactic radiosurgery (SRS) in patients with intracranial ependymomas who had received previous fractionated radiation therapy, we compared tumor control, survival, and complications with tumor grade, volume, age of patients, and imaging characteristics.
  • Lower histological tumor grade was not significantly associated with better progression-free survival (P = 0.725).
  • Factors associated with an improved progression-free survival included smaller tumor volume and homogeneous tumor contrast enhancement in low-grade ependymomas.
  • [MeSH-major] Brain Neoplasms / epidemiology. Brain Neoplasms / surgery. Ependymoma / epidemiology. Ependymoma / surgery. Neoplasm Recurrence, Local / epidemiology. Neoplasm Recurrence, Local / prevention & control. Outcome Assessment (Health Care) / methods. Radiosurgery / statistics & numerical data
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Female. Humans. Incidence. Male. Middle Aged. Pennsylvania / epidemiology. Retrospective Studies. Risk Assessment / methods. Risk Factors. Treatment Outcome. Young Adult


32. Perrotta R, Tarico MS, Virzì D, Manzo G, Curreri S: [Morpho-functional iterative surgery in a patient with von Recklinghausen disease]. G Chir; 2010 Nov-Dec;31(11-12):543-8
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  • This disease has been linked with mutations of the NF1 gene which encodes tumor suppressor neurofibromin.
  • The cardinal features of the disorder are cafè-au-lait spots, axillary freckling, cutaneous neurofibromas and Lisch nodules, but there are a lot of wide variety of complications affecting almost every system of the body, including the eyes (optic glioma), the nervous system (intracranial tumors), the skeleton (short stature, scoliosis), the endocrine and cardiovascular system (hypertension).
  • [MeSH-major] Buttocks / surgery. Muscle Neoplasms / surgery. Neurofibromatosis 1 / surgery
  • [MeSH-minor] Female. Humans. Patient Satisfaction. Reconstructive Surgical Procedures. Treatment Outcome. Young Adult

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  • (PMID = 21232201.001).
  • [ISSN] 0391-9005
  • [Journal-full-title] Il Giornale di chirurgia
  • [ISO-abbreviation] G Chir
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Italy
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33. Moudden M, El Moutawakil B, Boulajaj FZ, Slassi I, Azhari A: [Granulocytic sarcoma of the brain revealed on vascular mode]. Rev Neurol (Paris); 2008 Jun-Jul;164(6-7):620-3
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  • Granulocytic sarcoma is a rare tumor composed of immature granulocytic cells.
  • An intracranial localization is unusual.
  • [MeSH-major] Brain Neoplasms / pathology. Sarcoma, Myeloid / pathology
  • [MeSH-minor] Adult. Headache / etiology. Hemiplegia / etiology. Humans. Magnetic Resonance Imaging. Male. Neurosurgical Procedures. Peroxidase / metabolism. Tomography, X-Ray Computed. Vomiting / etiology

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  • (PMID = 18565363.001).
  • [ISSN] 0035-3787
  • [Journal-full-title] Revue neurologique
  • [ISO-abbreviation] Rev. Neurol. (Paris)
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] EC 1.11.1.7 / Peroxidase
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34. Stark AM, Fritsch MJ, Claviez A, Dörner L, Mehdorn HM: Management of tectal glioma in childhood. Pediatr Neurol; 2005 Jul;33(1):33-8
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  • Clinical symptoms are usually associated with increased intracranial pressure.
  • This report discusses the management of this rare tumor in children.
  • Ten patients presented with symptoms associated with increased intracranial pressure, one patient presented with ataxia, and in one case tectal glioma was an incidental finding.
  • First-line therapy was endoscopic third ventriculostomy in 5 cases (42%), ventriculoperitoneal shunting in 6 cases (50%), and combined partial tumor resection and shunting in one case.
  • Effective treatment for hydrocephalus is essential; the tumor should be monitored by regular clinical examination and magnetic resonance imaging.
  • Biopsy is warranted in cases with tumor progression.
  • [MeSH-major] Brain Neoplasms / pathology. Brain Neoplasms / therapy. Glioma / pathology. Glioma / therapy. Superior Colliculi / pathology
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Disease Management. Female. Follow-Up Studies. Humans. Infant. Male. Retrospective Studies

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  • (PMID = 15876519.001).
  • [ISSN] 0887-8994
  • [Journal-full-title] Pediatric neurology
  • [ISO-abbreviation] Pediatr. Neurol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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35. Zhou LF, Du G, Mao Y, Zhang R: Diagnosis and surgical treatment of brainstem hemangioblastomas. Surg Neurol; 2005 Apr;63(4):307-15; discussion 315-6
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  • (1) patients with a single tumor on the brainstem which was verified by surgery and pathology;.
  • RESULTS: Thirty-three patients with BSHs were identified, accounting for 15.5% of all intracranial hemangioblastomas surgically treated from August 1989 to May 2002 in Huashan Hospital.
  • Total tumor removal was achieved in 31 patients (94%), and incomplete removal in 2 cases.
  • [MeSH-major] Cerebellar Neoplasms / surgery. Cerebellar Neoplasms / therapy. Embolization, Therapeutic. Hemangioblastoma / surgery. Hemangioblastoma / therapy
  • [MeSH-minor] Adolescent. Adult. Aged. Combined Modality Therapy. Female. Humans. Hyperthermia, Induced. Hypotension. Male. Middle Aged. Prognosis. Retrospective Studies. Treatment Outcome

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  • (PMID = 15808704.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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36. Chan CH, Fabinyi GC, Kalnins RM: An unusual case of tumor-to-cavernoma metastasis. A case report and literature review. Surg Neurol; 2006 Apr;65(4):402-8, discussion 409
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  • [Title] An unusual case of tumor-to-cavernoma metastasis. A case report and literature review.
  • BACKGROUND: Metastases of systemic neoplasia to preexisting intracranial mass lesions are uncommon phenomena.
  • Tumor-to-intracranial cavernoma metastases are even more unusual and rarely reported.
  • We describe here a case of melanoma to intracranial cavernoma metastasis.
  • CONCLUSION: This case report represents the third recorded case of tumor-to-intracranial cavernoma metastasis and the first melanoma to intracranial cavernoma metastasis.
  • An extensive literature review of tumor-to-intracranial tumor metastases was conducted and disclosed an increase in reporting of the uncommon phenomenon of metastasis into preexisting intracranial lesions.
  • It should therefore be considered as a differential diagnosis in patients with history of systemic cancer who present with progression of preexistent intracranial lesions.
  • [MeSH-major] Brain Neoplasms / pathology. Brain Neoplasms / secondary. Hemangioma, Cavernous, Central Nervous System / pathology. Melanoma / secondary. Neoplasm Metastasis / pathology
  • [MeSH-minor] Adult. Craniotomy. Female. Humans. Magnetic Resonance Imaging. Neurosurgical Procedures. Occipital Lobe / pathology. Occipital Lobe / surgery. Parietal Lobe / pathology. Parietal Lobe / surgery. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 16531212.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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37. Coluccia D, Fandino J, Fujioka M, Cordovi S, Muroi C, Landolt H: Intraoperative 5-aminolevulinic-acid-induced fluorescence in meningiomas. Acta Neurochir (Wien); 2010 Oct;152(10):1711-9
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  • METHODS: A total of 33 consecutive patients undergoing resection of intracranial meningiomas from December 2007 to August 2009 were included in this study.
  • Intraoperative 440 nm fluorescence was applied periodically during and at the end of resection in order to detect tumor-infiltrated sites.
  • The fluorescence of the tumor was evaluated intraoperatively by the surgeon and confirmed by subsequent video analysis.
  • 5-ALA-induced fluorescence of the tumor was confirmed in a total of 31 (94%) patients.
  • [MeSH-major] Aminolevulinic Acid. Fluorescence. Meningeal Neoplasms / diagnosis. Meningioma / diagnosis. Monitoring, Intraoperative / methods. Photosensitizing Agents
  • [MeSH-minor] Adult. Aged. Female. Humans. Male. Middle Aged. Neoplasm Invasiveness / diagnosis. Neoplasm Recurrence, Local / prevention & control. Preoperative Care / methods. Ultraviolet Rays

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  • (PMID = 20535506.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article
  • [Publication-country] Austria
  • [Chemical-registry-number] 0 / Photosensitizing Agents; 88755TAZ87 / Aminolevulinic Acid
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38. Sumrall A, Fredericks R, Berthold A, Shumaker G: Lenalidomide stops progression of multifocal epithelioid hemangioendothelioma including intracranial disease. J Neurooncol; 2010 Apr;97(2):275-7
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  • [Title] Lenalidomide stops progression of multifocal epithelioid hemangioendothelioma including intracranial disease.
  • Epithelioid Hemangioendothelioma (EH) is a rare soft-tissue tumor which may present as an isolated tumor or can spread to affect internal organs.
  • This case report describes a young woman who developed cutaneous EH with concurrent intracranial disease during pregnancy.
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Brain Neoplasms / drug therapy. Hemangioendothelioma, Epithelioid / drug therapy. Thalidomide / analogs & derivatives
  • [MeSH-minor] Adult. Clinical Trials as Topic. Female. Humans. Magnetic Resonance Imaging. Tomography, X-Ray Computed

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  • (PMID = 19898746.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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39. Epstein NE, Drexler S, Schneider J: Clear cell meningioma of the cauda equina in an adult: case report and literature review. J Spinal Disord Tech; 2005 Dec;18(6):539-43
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  • [Title] Clear cell meningioma of the cauda equina in an adult: case report and literature review.
  • In the pediatric population, clear cell meningiomas are more frequently intracranial than intraspinal in location.
  • Frozen-section diagnosis confirmed clear cell tumor.
  • Negative postoperative chest, abdominal, and pelvic computed tomography studies ruled out tumor of renal cell origin.
  • The high recurrence rate for clear cell meningiomas in children requires repeated tumor resection with or without secondary radiation therapy.
  • [MeSH-major] Cauda Equina / pathology. Cauda Equina / surgery. Meningioma / diagnosis. Meningioma / surgery. Peripheral Nervous System Neoplasms / diagnosis. Peripheral Nervous System Neoplasms / surgery
  • [MeSH-minor] Adult. Female. Humans. Paresis / diagnosis. Paresis / etiology. Treatment Outcome

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  • (PMID = 16306847.001).
  • [ISSN] 1536-0652
  • [Journal-full-title] Journal of spinal disorders & techniques
  • [ISO-abbreviation] J Spinal Disord Tech
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 10
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40. Gupta A, Ahmad FU, Sharma MC, Garg A, Mehta VS: Cerebellopontine angle meningeal melanocytoma: a rare tumor in an uncommon location. Case report. J Neurosurg; 2007 Jun;106(6):1094-7
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  • [Title] Cerebellopontine angle meningeal melanocytoma: a rare tumor in an uncommon location. Case report.
  • Meningeal melanocytomas are uncommon intracranial tumors and their occurrence at the cerebellopontine angle (CPA) is extremely rare.
  • The authors describe the case of a 58-year-old woman who presented with a left CPA tumor; on the basis of histopathological studies after resection, a diagnosis of meningeal melanocytoma was reached.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cerebellar Neoplasms / surgery. Cerebellopontine Angle / pathology. Cerebellopontine Angle / surgery. Melanoma / pathology. Melanoma / surgery. Meningioma / pathology. Meningioma / surgery
  • [MeSH-minor] Adult. Female. Humans. Magnetic Resonance Imaging. Melanins / metabolism. Neurosurgical Procedures

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  • (PMID = 17564187.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Melanins
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41. Heiser MA, Waldron JS, Tihan T, Parsa AT, Cheung SW: Temporal fossa hemangiopericytoma: a case series. Otol Neurotol; 2009 Oct;30(7):985-9
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  • PATIENTS: Intracranial HPCs within the temporal fossa.
  • INTERVENTIONS: Craniotomy for either subtotal or gross total tumor excision.
  • Gross total tumor excision was achieved in 2 patients, whereas subtotal tumor excision was achieved in 3 patients.
  • Reasons for subtotal resection included excessive intraoperative blood loss and inextricable tumor.
  • Histologically, all tumors were composed of tightly packed, randomly oriented (jumbled-up) tumor cells with little intervening collagen.
  • CONCLUSION: Management of temporal fossa HPC is challenging because clinical presentation is often late, and extent of tumor excision is constrained by vital structures in the cranial base and intracranial contents.
  • A multidisciplinary approach with neurosurgery and neurotology undertaken to achieve the most complete tumor resection possible, whereas minimizing morbidity are likely to confer a longer period of symptom-free survival and improves curability of these difficult lesions.
  • [MeSH-major] Hemangiopericytoma / pathology. Hemangiopericytoma / surgery. Skull Neoplasms / pathology. Skull Neoplasms / surgery
  • [MeSH-minor] Adult. Antigens, CD34 / metabolism. Delayed Diagnosis. Disease-Free Survival. Female. Headache / etiology. Humans. Male. Middle Aged. Neurosurgical Procedures. Treatment Outcome

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  • (PMID = 19707170.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34
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42. Vorasubin N, Sang U H, Mafee M, Nguyen QT: Glossopharyngeal schwannomas: a 100 year review. Laryngoscope; 2009 Jan;119(1):26-35
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  • Tumors can occur anywhere along the CNIX; however, the majority of symptomatic cases are intracranial/intraosseous, which present with vestibulocochlear dysfunction.
  • We present a case where notching and displacement of CNVIII by the tumor can be appreciated on MRI, allowing for the first correlation between clinical symptoms and imaging findings.
  • CONCLUSION: Glossopharyngeal schwannomas usually present with vestibulocochlear rather than glossopharyngeal symptoms, likely due to CNVIII compression and displacement by tumor, which can be better appreciated with modern imaging.
  • The tumor's location posterior and medial to CNVIII combined with the complex CNVIII tonotopic organization may account for the preferential mid-frequency hearing loss seen in these patients.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged

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  • (PMID = 19117318.001).
  • [ISSN] 1531-4995
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 39
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43. Cordier D, Forrer F, Kneifel S, Sailer M, Mariani L, Mäcke H, Müller-Brand J, Merlo A: Neoadjuvant targeting of glioblastoma multiforme with radiolabeled DOTAGA-substance P--results from a phase I study. J Neurooncol; 2010 Oct;100(1):129-36
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  • Complete surgical resection beyond tumor margins cannot be achieved in glioblastoma multiforme (GBM) because of infiltrative nature.
  • In several cancers, neoadjuvant treatment has been implemented to reduce the risk of tumor cell spreading during resection.
  • In GBM, the objective of a neoadjuvant approach is reduction of tumor cells within the main tumor mass and beyond in the infiltration zone.
  • Such an approach can only be performed if elevated intracranial pressure can be medically controlled.
  • In a previous study with recurrent gliomas, we showed that local intratumoral injection of radiolabeled DOTAGA-substance P substantially inhibited further growth and led to radionecrotic transformation of the tumor (CCR 2006).
  • Neoadjuvant injection of [90Y]-DOTAGA-substance P was feasible without decompensation of intracranial pressure.
  • The high extent of resection and concomitant irradiation of tumor cells in the infiltration zone may be prognostically relevant.
  • [MeSH-major] Brain Neoplasms / drug therapy. Brain Neoplasms / radiotherapy. Glioblastoma / drug therapy. Glioblastoma / radiotherapy. Heterocyclic Compounds, 1-Ring / therapeutic use. Neoadjuvant Therapy / methods. Substance P / analogs & derivatives
  • [MeSH-minor] Adult. Aged. Combined Modality Therapy. Diagnostic Imaging / methods. Female. Follow-Up Studies. Humans. Male. Middle Aged. Organometallic Compounds. Radiopharmaceuticals / therapeutic use

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  • (PMID = 20217458.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Heterocyclic Compounds, 1-Ring; 0 / Organometallic Compounds; 0 / Radiopharmaceuticals; 0 / substance P, 1,4,7,10-tetraazacyclododecane-1-glutaric acid-4,7,10-triacetic acid-arginyl(1)-; 33507-63-0 / Substance P
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44. Wu AH, Drees JC, Wang H, VandenBerg SR, Lal A, Henner WD, Pillai R: Gene expression profiles help identify the tissue of origin for metastatic brain cancers. Diagn Pathol; 2010;5:26
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  • BACKGROUND: Metastatic brain cancers are the most common intracranial tumor and occur in about 15% of all cancer patients.
  • In up to 10% of these patients, the primary tumor tissue remains unknown, even after a time consuming and costly workup.
  • It measures the expression pattern of 1,550 genes in these tumors and compares it to the expression pattern of a panel of 15 known tumor types.
  • METHODS: Fifteen fresh-frozen metastatic brain tumor specimens of known origins met specimen requirements.
  • [MeSH-major] Brain Neoplasms / genetics. Gene Expression Profiling. Gene Expression Regulation, Neoplastic. Neoplasms, Unknown Primary / genetics
  • [MeSH-minor] Adult. Biopsy. Female. Humans. Male. Middle Aged. Oligonucleotide Array Sequence Analysis. Predictive Value of Tests. Reagent Kits, Diagnostic. Reproducibility of Results. Young Adult

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  • [Cites] Arch Pathol Lab Med. 2007 Oct;131(10):1561-7 [17922593.001]
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  • (PMID = 20420692.001).
  • [ISSN] 1746-1596
  • [Journal-full-title] Diagnostic pathology
  • [ISO-abbreviation] Diagn Pathol
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Reagent Kits, Diagnostic
  • [Other-IDs] NLM/ PMC2867958
  • [General-notes] NLM/ Original DateCompleted: 20100609
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45. Yokosuka K, Ishii R, Suzuki Y, Hirano K, Ishii N, Sekihara Y, Hamazaki S, Nishimura H: Extraneural metastasis of high grade glioma without simultaneous central nervous system recurrence: case report. Neurol Med Chir (Tokyo); 2007 Jun;47(6):273-7
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  • He had undergone a shunt operation and three tumor removals during a 6-year period.
  • Autopsy revealed tumor masses in the peritoneum, pleura, bone marrow, lymph nodes, and other organs, but no recurrent tumor of the primary lesion or metastases to other areas in the central nervous system.
  • Systemic metastases from primary intracranial tumors are rare, but are likely to become more frequent as the prognosis of patients with brain tumors improves and the duration of survival lengthens.
  • [MeSH-major] Bone Marrow Neoplasms / secondary. Brain Neoplasms / pathology. Glioma / secondary. Neoplasm Metastasis / physiopathology. Peritoneal Neoplasms / secondary. Pleural Neoplasms / secondary
  • [MeSH-minor] Adult. Central Nervous System / pathology. Drug Therapy. Fatal Outcome. Humans. Lymph Nodes / pathology. Male. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / physiopathology. Pulvinar / pathology. Pulvinar / physiopathology. Radiotherapy. Survival Rate

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  • (PMID = 17587781.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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46. Ichimura S, Yoshida K, Kawase T: Surgical approach for hypoglossal schwannomas to prevent deformity of the atlanto-occipital joint. Acta Neurochir (Wien); 2009 Jun;151(6):575-9
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  • The intracranial part of the tumor was removed in all type B cases.
  • Radiotherapy was added for the residual tumor.
  • [MeSH-major] Atlanto-Occipital Joint / surgery. Cranial Nerve Neoplasms / surgery. Craniotomy / methods. Hypoglossal Nerve Diseases / surgery. Neurilemmoma / surgery. Skull Base Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Cervical Atlas / anatomy & histology. Cervical Atlas / surgery. Female. Foramen Magnum / anatomy & histology. Foramen Magnum / surgery. Humans. Joint Diseases / etiology. Joint Diseases / prevention & control. Laminectomy / methods. Magnetic Resonance Imaging. Male. Middle Aged. Occipital Bone / anatomy & histology. Occipital Bone / surgery. Postoperative Complications / etiology. Postoperative Complications / prevention & control. Spinal Fractures / etiology. Spinal Fractures / prevention & control. Treatment Outcome

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  • (PMID = 19337683.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Austria
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47. Dusick JR, Esposito F, Kelly DF, Cohan P, DeSalles A, Becker DP, Martin NA: The extended direct endonasal transsphenoidal approach for nonadenomatous suprasellar tumors. J Neurosurg; 2005 May;102(5):832-41
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  • Twenty-six procedures for tumor removal were performed in 24 patients (ages 9-79 years), including two repeated operations for residual tumor.
  • Of 13 patients with tumor-related visual loss, 85% improved postoperatively.
  • The only permanent neurological deficit was anosmia in one patient; there were no intracranial vascular injuries.
  • [MeSH-major] Brain Neoplasms / surgery. Minimally Invasive Surgical Procedures / methods. Neurosurgical Procedures / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Brain Diseases / surgery. Central Nervous System Cysts / surgery. Child. Craniopharyngioma / surgery. Epidermal Cyst / surgery. Humans. Meningeal Neoplasms / surgery. Meningioma / surgery. Middle Aged. Pituitary Neoplasms / surgery. Postoperative Complications. Sphenoid Bone. Treatment Outcome

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  • [CommentIn] J Neurosurg. 2005 May;102(5):825-7; discussion 827-8 [15926704.001]
  • (PMID = 15926706.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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48. Cherekaev VA, Gol'bin DA, Kapitanov DN, Belov AI, Arustamian SR, Gromova VV, Imaev AA: [Surgical treatment of extensive craniofacial juvenile angiofibromas]. Zh Vopr Neirokhir Im N N Burdenko; 2009 Apr-Jun;(2):9-14; discussion 14-5
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  • Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign tumor occurring almost exclusively in adolescent and young adult males.
  • The tumor is characterized by slow progression, aggressive growth, high vascularization and increased rate of persistence and recurrence.
  • From 2000 till 2008 29 consecutive male patients with JNA Fisch grade III and IV (intracranial extradural or intradural extension) were operated in Burdenko Neurosurgical Institute (Moscow, Russia).
  • 4 cases are presented (3 patients with Fisch grade IV tumor and 1 with grade III).
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery. Otorhinolaryngologic Surgical Procedures / methods
  • [MeSH-minor] Adolescent. Adult. Child. Humans. Male. Treatment Outcome. Young Adult

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  • (PMID = 19569543.001).
  • [ISSN] 0042-8817
  • [Journal-full-title] Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko
  • [ISO-abbreviation] Zh Vopr Neirokhir Im N N Burdenko
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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49. Tamhankar MA, Volpe NJ, Loevner LA, Palmer JN, Feldman M: Primary sinonasal undifferentiated carcinoma presenting with bilateral retrobulbar optic neuropathy. J Neuroophthalmol; 2007 Sep;27(3):189-92
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  • Brain MRI showed an intracranial but extra-axial mass in the floor of the anterior cranial fossa extending along the olfactory groove and into the sinonasal vault.
  • Endoscopic biopsy showed a high-grade neoplasm consistent with sinonasal undifferentiated carcinoma.
  • This case report highlights an unusual clinical presentation for this rare and aggressive neoplasm.
  • [MeSH-major] Carcinoma / complications. Optic Nerve Diseases / etiology. Paranasal Sinus Neoplasms / complications. Vision, Low / etiology
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biomarkers, Tumor. Biopsy. Cranial Fossa, Anterior / pathology. Cranial Fossa, Anterior / physiopathology. Fatal Outcome. Functional Laterality. Humans. Magnetic Resonance Imaging. Male. Nasal Cavity / pathology. Nasal Cavity / physiopathology. Neoplasm Metastasis / pathology. Optic Nerve / pathology. Optic Nerve / physiopathology. Orbit / pathology. Orbit / physiopathology. Paranasal Sinuses / pathology. Paranasal Sinuses / physiopathology. Radiotherapy. Treatment Failure

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  • (PMID = 17895819.001).
  • [ISSN] 1070-8022
  • [Journal-full-title] Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
  • [ISO-abbreviation] J Neuroophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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50. Menkü A, Oktem IS, Kontaş O, Akdemir H: Atypical intracerebral schwannoma mimicking glial tumor: case report. Turk Neurosurg; 2009 Jan;19(1):82-5
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  • [Title] Atypical intracerebral schwannoma mimicking glial tumor: case report.
  • The initial diagnosis being considered was primary intracranial tumor, including high-grade astrocytoma, metastasis or lymphoma Histopathological examination revealed schwannoma.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Epilepsy / pathology. Magnetic Resonance Imaging. Neurilemmoma / pathology
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Humans. Male


51. Brackmann DE, Teufert KB: Chondrosarcoma of the skull base: long-term follow-up. Otol Neurotol; 2006 Oct;27(7):981-91
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  • OBJECTIVE: Chondrosarcoma of the skull base is an uncommon neoplasm comprising 0.15% of all intracranial tumors and 6% of skull base neoplasms.
  • Of the seven patients who underwent surgery via the infratemporal fossa approach, one had residual tumor found at 1 year, but remained alive and well for 21 years after the surgery.
  • The improved exposure afforded by this approach seems to have resulted in more complete extirpation of the tumor and a decrease in the recurrence rate.
  • [MeSH-major] Chondrosarcoma / therapy. Neoplasm Recurrence, Local / surgery. Skull Base / surgery. Skull Base Neoplasms / therapy
  • [MeSH-minor] Adult. Ear, Middle. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm, Residual. Petrous Bone. Radiotherapy, Adjuvant. Retrospective Studies. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 17006349.001).
  • [ISSN] 1531-7129
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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52. Park IH, Ro J, Lee KS, Nam BH, Kwon Y, Shin KH: Trastuzumab treatment beyond brain progression in HER2-positive metastatic breast cancer. Ann Oncol; 2009 Jan;20(1):56-62
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  • RESULTS: Overall survival after the diagnosis of BM as well as time to progression (TTP) of intracranial tumors was prolonged in patients who received trastuzumab after BM was diagnosed.
  • In the multivariate Cox regression model, age at BM <50 years, disease-free interval >or=24 months, TTP of intracranial tumor >or=4.8 months, and trastuzumab treatment after BM were significantly associated with longer survival after the onset of BM.


53. Kramer K, Humm JL, Souweidane MM, Zanzonico PB, Dunkel IJ, Gerald WL, Khakoo Y, Yeh SD, Yeung HW, Finn RD, Wolden SL, Larson SM, Cheung NK: Phase I study of targeted radioimmunotherapy for leptomeningeal cancers using intra-Ommaya 131-I-3F8. J Clin Oncol; 2007 Dec 1;25(34):5465-70
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  • Tumor response was determined by clinical, radiographic, and cytologic criteria.
  • Dose-limiting toxicity was reached at the 20-mCi dose, when transient elevations in intracranial pressure and chemical meningitis were seen.
  • [MeSH-major] Antibodies, Monoclonal / immunology. Immunoglobulin G / immunology. Immunotoxins / administration & dosage. Iodine Radioisotopes / administration & dosage. Meningeal Neoplasms / radiotherapy. Radioimmunotherapy / methods
  • [MeSH-minor] Adolescent. Adult. Animals. Cerebellar Neoplasms / immunology. Cerebellar Neoplasms / radionuclide imaging. Cerebellar Neoplasms / radiotherapy. Child. Child, Preschool. Humans. Infant. Medulloblastoma / immunology. Medulloblastoma / radionuclide imaging. Medulloblastoma / radiotherapy. Mice. Mice, Inbred BALB C. Middle Aged. Neuroblastoma / immunology. Neuroblastoma / radionuclide imaging. Neuroblastoma / radiotherapy

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  • (PMID = 18048828.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA72868
  • [Publication-type] Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / 3F8 antibody; 0 / Antibodies, Monoclonal; 0 / Immunoglobulin G; 0 / Immunotoxins; 0 / Iodine Radioisotopes
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54. Kano H, Niranjan A, Mongia S, Kondziolka D, Flickinger JC, Lunsford LD: The role of stereotactic radiosurgery for intracranial hemangioblastomas. Neurosurgery; 2008 Sep;63(3):443-50; discussion 450-1
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  • [Title] The role of stereotactic radiosurgery for intracranial hemangioblastomas.
  • OBJECTIVE: To evaluate the role of stereotactic radiosurgery (SRS) in the management of recurrent or residual intracranial hemangioblastomas, we assessed tumor control, survival, and complications in 32 consecutive patients.
  • METHODS: We retrospectively reviewed records of 32 consecutive hemangioblastoma patients (74 intracranial tumors) who underwent gamma knife SRS.
  • Follow-up imaging studies demonstrated tumor control in 68 tumors (91.9%).
  • Factors associated with an improved progression-free survival included von Hippel-Lindau disease-associated hemangioblastoma, solid tumor, lower tumor volume, and greater marginal dose.
  • CONCLUSION: SRS is an important tool in the management of hemangioblastomas and is associated with a high tumor control rate and a low risk of adverse radiation effects.
  • [MeSH-major] Cerebellar Neoplasms / surgery. Hemangioblastoma / surgery. Radiosurgery / trends
  • [MeSH-minor] Adult. Aged. Female. Follow-Up Studies. Humans. Male. Middle Aged. Retrospective Studies. Survival Rate / trends. Young Adult

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  • (PMID = 18812955.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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55. Naggara O, Brami-Zylberberg F, Rodrigo S, Raynal M, Meary E, Godon-Hardy S, Oppenheim C, Meder JF: [Imaging of intracranial metastases in adults]. J Radiol; 2006 Jun;87(6 Pt 2):792-806
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  • [Title] [Imaging of intracranial metastases in adults].
  • Intracranial metastases account for up to 35% of intracranial tumors in adult.
  • Any systemic tumor can metastasize to the brain; the most common primaries include lung, breast and melanoma.
  • [MeSH-major] Brain Neoplasms / diagnosis. Brain Neoplasms / secondary

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  • (PMID = 16778748.001).
  • [ISSN] 0221-0363
  • [Journal-full-title] Journal de radiologie
  • [ISO-abbreviation] J Radiol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 30
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56. Mehrazin M, Rahmat H, Yavari P: Epidemiology of primary intracranial tumors in Iran, 1978-2003. Asian Pac J Cancer Prev; 2006 Apr-Jun;7(2):283-8
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  • [Title] Epidemiology of primary intracranial tumors in Iran, 1978-2003.
  • Data abstracted from the patients' clinical records included age at the time of admission , sex, histological diagnosis and tumor location.
  • In conclusion, the results present an important epidemiological basis for understanding of the brain tumor burden in Iran.
  • [MeSH-major] Brain Neoplasms / epidemiology. Brain Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Age Distribution. Aged. Aged, 80 and over. Child. Child, Preschool. Female. Hospitals, University. Humans. Infant. Iran / epidemiology. Male. Middle Aged. Retrospective Studies. Sex Distribution

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  • (PMID = 16839224.001).
  • [ISSN] 1513-7368
  • [Journal-full-title] Asian Pacific journal of cancer prevention : APJCP
  • [ISO-abbreviation] Asian Pac. J. Cancer Prev.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Thailand
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57. Ayberk G, Ozveren MF, Yildirim T, Ercan K, Cay EK, Koçak A: Review of a series with abducens nerve palsy. Turk Neurosurg; 2008 Oct;18(4):366-73
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  • The causes of the abducens nerve paralysis of our patients were as follows: two cases with head trauma, three cases with pituitary tumors, one case with sphenoid sinus mucocele, one case with greater superficial petrosal nerve cellular schwannoma at the petrous apex, one case with hypertensive intraventricular hemmorhage, one case with hydrocephalus, and one case with parotid tumor and skull base/brain stem invasion.
  • [MeSH-minor] Adolescent. Adult. Botulinum Toxins, Type A / therapeutic use. Brain Neoplasms / complications. Brain Neoplasms / pathology. Child. Craniocerebral Trauma / complications. Craniocerebral Trauma / pathology. Diplopia / etiology. Humans. Intracranial Pressure / physiology. Magnetic Resonance Imaging. Male. Middle Aged. Mucocele / complications. Mucocele / pathology. Neuromuscular Agents / therapeutic use. Paralysis / pathology. Paralysis / surgery. Retrospective Studies. Tomography, X-Ray Computed. Young Adult

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  • (PMID = 19107682.001).
  • [ISSN] 1019-5149
  • [Journal-full-title] Turkish neurosurgery
  • [ISO-abbreviation] Turk Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
  • [Chemical-registry-number] 0 / Neuromuscular Agents; EC 3.4.24.69 / Botulinum Toxins, Type A
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58. Schomas DA, Laack NN, Brown PD: Low-grade gliomas in older patients: long-term follow-up from Mayo Clinic. Cancer; 2009 Sep 1;115(17):3969-78
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  • METHODS: The authors retrospectively searched their tumor registry for the records of adult patients (> or =18 years) diagnosed as having nonpilocytic LGG between 1960 and 1992 at Mayo Clinic.
  • CONCLUSIONS: This retrospective series of older patients suggests that intracranial LGG in this age group behaves aggressively.

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  • (PMID = 19536875.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] ENG
  • [Grant] United States / NCRR NIH HHS / RR / UL1 RR024150; None / None / / UL1 RR024150-01; United States / NCRR NIH HHS / RR / 1 UL1 RR024150-01; United States / NCRR NIH HHS / RR / UL1 RR024150-01
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS140676; NLM/ PMC2789453
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59. Mookerjee RP, Dalton RN, Davies NA, Hodges SJ, Turner C, Williams R, Jalan R: Inflammation is an important determinant of levels of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine (ADMA) in acute liver failure. Liver Transpl; 2007 Mar;13(3):400-5
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  • A total of 8 patients required treatment for raised intracranial pressure and all patients were managed with standard of care, including full mechanical ventilation and veno-venous hemofiltration.
  • [MeSH-minor] Adult. C-Reactive Protein / metabolism. Female. Humans. Interleukin-1beta / blood. Interleukin-6 / blood. Liver / metabolism. Male. Middle Aged. Predictive Value of Tests. Severity of Illness Index. Tumor Necrosis Factor-alpha / blood

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  • [Copyright] (c) 2007 AASLD.
  • (PMID = 17318866.001).
  • [ISSN] 1527-6465
  • [Journal-full-title] Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
  • [ISO-abbreviation] Liver Transpl.
  • [Language] eng
  • [Grant] United Kingdom / Medical Research Council / / G0601448
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Interleukin-1beta; 0 / Interleukin-6; 0 / Tumor Necrosis Factor-alpha; 0 / dimethylarginine; 9007-41-4 / C-Reactive Protein; 94ZLA3W45F / Arginine; EC 1.14.13.39 / Nitric Oxide Synthase
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60. Berne JP, Bouchot O, Jazayeri S, Tatou E, Gomez-Bielfeld MC, Martin L, Brenot R, David M: [Cardiac papillary fibroelastoma, a rare valvular source of cerebral embolism: report of two cases]. Ann Cardiol Angeiol (Paris); 2009 Feb;58(1):61-3
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  • The only curative treatment consists of the excision of the tumor under cardiopulmonary bypass.
  • [MeSH-major] Aortic Valve. Endocardial Fibroelastosis / complications. Heart Neoplasms / complications. Intracranial Embolism / etiology. Mitral Valve. Papillary Muscles
  • [MeSH-minor] Adult. Cardiac Surgical Procedures / methods. Echocardiography, Transesophageal. Fibroma. Humans. Male. Middle Aged. Treatment Outcome

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  • (PMID = 18980749.001).
  • [ISSN] 1768-3181
  • [Journal-full-title] Annales de cardiologie et d'angéiologie
  • [ISO-abbreviation] Ann Cardiol Angeiol (Paris)
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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61. Elsharkawy AA, Kamal EM, Tawfik A, Zaher A, Kasem M: Juvenile nasopharyngeal angiofibroma with intracranial extension: analysis of 23 Egyptian patients. Int J Pediatr Otorhinolaryngol; 2010 Jul;74(7):755-9
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  • [Title] Juvenile nasopharyngeal angiofibroma with intracranial extension: analysis of 23 Egyptian patients.
  • The purpose of this study was to present our experience with definitive surgical management of patients with Juvenile nasopharyngeal angiofibroma with intracranial extension.
  • Complete resection of the tumor was achieved in 19 patients with residual or recurrence in four patients.
  • The subcranial transfacial transmaxillary approach avoids the complications of craniotomy and provides adequate access for excision of Juvenile nasopharyngeal angiofibroma with intracranial extradural extension.
  • [MeSH-major] Angiofibroma / surgery. Nasopharyngeal Neoplasms / surgery. Otorhinolaryngologic Surgical Procedures / methods
  • [MeSH-minor] Adolescent. Child. Cranial Fossa, Anterior / pathology. Cranial Fossa, Anterior / surgery. Cranial Fossa, Middle / pathology. Cranial Fossa, Middle / surgery. Egypt. Embolization, Therapeutic. Gelatin Sponge, Absorbable. Hemostatics. Humans. Male. Maxillary Artery. Neoplasm Invasiveness. Postoperative Complications. Preoperative Care. Retrospective Studies. Young Adult

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  • [Copyright] Copyright 2010 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 20394990.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Hemostatics
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62. Asri F, Tazi I, Maaroufi K, El Moudden A, Ghannane H, Ait Benali S: [Cerebral hydatic cyst and psychiatric disorders. Two cases]. Encephale; 2007 Mar-Apr;33(2):216-9
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  • Symptoms are especially the diffuse headache associated to various neurological signs in relation with sits of the tumor.
  • The psychiatrics symptoms depends on its localization, sides, intracranial hypertension, and the previous personality.
  • Of course, the surgical ablation of the tumor can be sufficient to attenuate the psychiatric symptoms but the recourse to a specific treatment can prove to be necessary to act on the precise targets.
  • [MeSH-minor] Adult. Diagnosis, Differential. Hallucinations / diagnosis. Hallucinations / parasitology. Hallucinations / psychology. Humans. Male. Middle Aged

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  • (PMID = 17675918.001).
  • [ISSN] 0013-7006
  • [Journal-full-title] L'Encéphale
  • [ISO-abbreviation] Encephale
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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63. Kounin GK, Romansky KV, Traykov LD, Shotekov PM, Stoilova DZ: Primary spinal melanoma with bilateral papilledema. Clin Neurol Neurosurg; 2005 Oct;107(6):525-7
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  • The only clinical finding was intracranial hypertension with papilledema.
  • Primary leptomeningeal melanoma is an extremely rare spinal tumor.
  • Its clinical presentation with signs of increased intracranial pressure but without cord symptoms is unusual.
  • [MeSH-major] Melanoma / diagnosis. Papilledema / etiology. Spinal Cord Neoplasms / diagnosis
  • [MeSH-minor] Adult. Cerebrospinal Fluid / cytology. Cervical Vertebrae / pathology. Diagnosis, Differential. Erythrocyte Count. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Neoplasm Invasiveness. Spinal Cord / pathology. Spinal Cord Compression / diagnosis. Spinal Cord Compression / surgery. Tomography, X-Ray Computed

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  • (PMID = 16202828.001).
  • [ISSN] 0303-8467
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports
  • [Publication-country] Netherlands
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64. Yuan X, Hu J, Belladonna ML, Black KL, Yu JS: Interleukin-23-expressing bone marrow-derived neural stem-like cells exhibit antitumor activity against intracranial glioma. Cancer Res; 2006 Mar 1;66(5):2630-8
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  • [Title] Interleukin-23-expressing bone marrow-derived neural stem-like cells exhibit antitumor activity against intracranial glioma.
  • Neural progenitor-like cells have been isolated from bone marrow and the cells have the ability of tracking intracranial tumor.
  • However, the capacity of the cells to deliver molecules for activating immune response against intracranial tumor and the identity of cellular and molecular factors that are involved in such immune responses have yet to be elucidated.
  • Here, we isolated neural stem-like cells from the bone marrow of adult mice.
  • By genetically manipulating bone marrow-derived neural stem-like cells (BM-NSC) to express a recently discovered cytokine, interleukin (IL)-23, the cells showed protective effects in intracranial tumor-bearing C57BL/6 mice.
  • Furthermore, the IL-23-expressing BM-NSC-treated survivors were resistant to the same tumor rechallenge associated with enhanced IFN-gamma, but not IL-17, expression in the brain tissue.
  • Taken together, these data suggest that IL-23-expressing BM-NSCs can effectively induce antitumor immunity against intracranial gliomas.
  • [MeSH-major] Bone Marrow Cells / immunology. Brain Neoplasms / therapy. Glioma / therapy. Immunotherapy, Adoptive / methods. Interleukins / biosynthesis. Neurons / immunology. Stem Cells / immunology

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  • (PMID = 16510582.001).
  • [ISSN] 0008-5472
  • [Journal-full-title] Cancer research
  • [ISO-abbreviation] Cancer Res.
  • [Language] eng
  • [Grant] United States / NINDS NIH HHS / NS / 1K23 NS02232; United States / NINDS NIH HHS / NS / 1R01 NS048959; United States / NINDS NIH HHS / NS / 1R21 NS048879
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Il23a protein, mouse; 0 / Interleukin-23; 0 / Interleukin-23 Subunit p19; 0 / Interleukins
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65. El Kettani A, Lamari H, Lahbil D, Rais L, Zaghloul K: [Bilateral optic neuropathy and non-Hodkin's lymphoma]. Bull Soc Belge Ophtalmol; 2006;(300):35-9
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  • Apart from infiltration, the optic nerve can be compressed by an intracranial or orbital tumor.
  • [MeSH-major] Lymphoma, Large B-Cell, Diffuse / diagnosis. Optic Nerve Neoplasms / diagnosis
  • [MeSH-minor] Adult. Antimetabolites, Antineoplastic / therapeutic use. Humans. Injections, Spinal. Male. Methotrexate / therapeutic use

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  • (PMID = 16903510.001).
  • [ISSN] 0081-0746
  • [Journal-full-title] Bulletin de la Société belge d'ophtalmologie
  • [ISO-abbreviation] Bull Soc Belge Ophtalmol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Belgium
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; YL5FZ2Y5U1 / Methotrexate
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66. Shnaper S, Desbaillets I, Brown DA, Murat A, Migliavacca E, Schluep M, Ostermann S, Hamou MF, Stupp R, Breit SN, de Tribolet N, Hegi ME: Elevated levels of MIC-1/GDF15 in the cerebrospinal fluid of patients are associated with glioblastoma and worse outcome. Int J Cancer; 2009 Dec 1;125(11):2624-30
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  • Determination of MIC-1/GDF15 protein levels by ELISA in the CSF of a cohort of 94 patients with intracranial tumors including gliomas, meningioma and metastasis revealed significantly increased concentrations in glioblastoma patients (median, 229 pg/ml) when compared with control cohort of patients treated for non-neoplastic diseases (median below limit of detection of 156 pg/ml, p < 0.0001, Mann-Whitney test).
  • In conclusion, MIC-1/GDF15 protein measured in the CSF may have diagnostic and prognostic value in patients with intracranial tumors.
  • [MeSH-major] Biomarkers, Tumor / cerebrospinal fluid. Brain Neoplasms / cerebrospinal fluid. Glioblastoma / cerebrospinal fluid. Growth Differentiation Factor 15 / cerebrospinal fluid
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Case-Control Studies. Cohort Studies. Enzyme-Linked Immunosorbent Assay. Female. Humans. Immunoenzyme Techniques. Male. Middle Aged. Prognosis. RNA, Messenger / genetics. RNA, Messenger / metabolism. Reverse Transcriptase Polymerase Chain Reaction. Survival Rate. Treatment Outcome. Young Adult

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  • (PMID = 19521960.001).
  • [ISSN] 1097-0215
  • [Journal-full-title] International journal of cancer
  • [ISO-abbreviation] Int. J. Cancer
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / GDF15 protein, human; 0 / Growth Differentiation Factor 15; 0 / RNA, Messenger
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67. Andrade FG, de Aguiar PH, Matushita H, Taricco MA, Oba-Shinjo SM, Marie SK, Teixeira MJ: Intracranial and spinal ependymoma: series at Faculdade de Medicina, Universidade de São Paulo. Arq Neuropsiquiatr; 2009 Sep;67(3A):626-32
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  • [Title] Intracranial and spinal ependymoma: series at Faculdade de Medicina, Universidade de São Paulo.
  • OBJECTIVE: Ependymomas are rare intracranial neuroepithelial tumors and the most common location is intramedullary.
  • METHOD: Data of clinical presentation, tumor location, duration of symptoms, degree of resection and complementary treatment of 34 patients with intracranial ependymoma and 31 with intramedullary ependymoma who underwent surgery in the last ten years were collected and correlated with the recurrence time and overall survival.
  • RESULTS: There was statistically significant correlation between the degree of resection and intracranial tumor location, although it is not a hallmark of recurrence.
  • CONCLUSION: The location of the intracranial tumor is connected with the degree of resection; however it is not a predictive factor to overall survival.
  • [MeSH-major] Brain Neoplasms / surgery. Ependymoma / surgery. Spinal Cord Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Disease-Free Survival. Female. Hospitals, University. Humans. Infant. Male. Middle Aged. Neoplasm Recurrence, Local. Young Adult


68. Cunliffe CH, Fischer I, Monoky D, Law M, Revercomb C, Elrich S, Kopp MJ, Zagzag D: Intracranial lesions mimicking neoplasms. Arch Pathol Lab Med; 2009 Jan;133(1):101-23
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  • [Title] Intracranial lesions mimicking neoplasms.
  • CONTEXT: A broad spectrum of nonneoplastic conditions can mimic a brain tumor, both clinically and radiologically.
  • OBJECTIVE: To illustrate the radiologic and pathologic features of nontumoral intracranial lesions that can clinically and radiologically mimic neoplasia.
  • [MeSH-major] Brain Diseases / diagnosis. Brain Neoplasms / diagnosis
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Female. Humans. Male. Middle Aged

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  • (PMID = 19123722.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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69. Ledwith MB, Bloom S, Maloney-Wilensky E, Coyle B, Polomano RC, Le Roux PD: Effect of body position on cerebral oxygenation and physiologic parameters in patients with acute neurological conditions. J Neurosci Nurs; 2010 Oct;42(5):280-7
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  • How body position influences brain tissue oxygen (PbtO2) and intracranial pressure (ICP) in critically ill neurosurgical patients remains poorly defined.
  • Thirty-three consecutive patients (mean +/- SD, age = 48.3 +/- 16.6 years; 22 men), admitted after traumatic brain injury, subarachnoid hemorrhage, or craniotomy for tumor, were evaluated in a neurocritical care unit at a level 1 academic trauma center.
  • [MeSH-minor] Acute Disease. Adult. Blood Pressure / physiology. Clinical Nursing Research. Female. Glasgow Coma Scale. Humans. Intracranial Pressure / physiology. Male. Middle Aged. Prospective Studies

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  • (PMID = 20968224.001).
  • [ISSN] 0888-0395
  • [Journal-full-title] The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses
  • [ISO-abbreviation] J Neurosci Nurs
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] S88TT14065 / Oxygen
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70. Roser F, Nakamura M, Ritz R, Bellinzona M, Dietz K, Samii M, Tatagiba MS: Proliferation and progesterone receptor status in benign meningiomas are not age dependent. Cancer; 2005 Aug 1;104(3):598-601
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  • Of these, 588 tumor specimens from 554 patients who underwent surgery between 1990 and 2000 were evaluated immunohistochemically.
  • Correlations with histologic subtype, disease recurrence-free survival, resection grade, location, size, vascularity, and tumor calcification were calculated as well.
  • CONCLUSIONS: Proliferation rates and PR status in benign intracranial meningiomas did not appear to be age dependent.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Cell Proliferation. Ki-67 Antigen / metabolism. Meningeal Neoplasms / metabolism. Meningioma / metabolism. Receptors, Progesterone / metabolism
  • [MeSH-minor] Adolescent. Adult. Age Distribution. Aged. Aged, 80 and over. Antibodies, Antinuclear. Antibodies, Monoclonal. Female. Humans. Immunoenzyme Techniques. Male. Middle Aged. Neoplasm Staging. Prognosis

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  • [Copyright] (c) 2005 American Cancer Society.
  • (PMID = 15952201.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Antinuclear; 0 / Antibodies, Monoclonal; 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 0 / MIB-1 antibody; 0 / Receptors, Progesterone
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71. Tong-tong W, Li-juan B, Zhi L, Yang L, Bo-ning L, Quan H: Clear cell meningioma with anaplastic features: case report and review of literature. Pathol Res Pract; 2010 May 15;206(5):349-54
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  • We present two cases of CCMs with anaplastic features in the intracranial and intraspinal region.
  • Magnetic resonance imaging revealed an intracranial lesion in the right frontal lobe in the male patient, and an intradural extramedullary lesion at C7 in the female patient.
  • Tumor cells were immunoreactive to epithelial membrane antigen (EMA) and vimentin, with a high MIB-1 index up to 40%.
  • Based on its aggressive behavior, we recommend postoperative adjuvant radiotherapy or chemotherapy even if total excision of the tumor has been performed, and MRI scans every 3-6 months during the first period of follow-up.
  • [MeSH-major] Frontal Lobe / pathology. Meningeal Neoplasms / pathology. Meningioma / pathology
  • [MeSH-minor] Adult. Aged. Anaplasia / pathology. Female. Humans. Magnetic Resonance Imaging. Male. Neoplasm Recurrence, Local / pathology

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  • [Copyright] (c) 2009. Published by Elsevier GmbH. All rights reserved.
  • (PMID = 19857933.001).
  • [ISSN] 1618-0631
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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72. Leonetti JP, Anderson DE, Marzo SJ, Origitano TC, Shirazi M: Intracranial schwannomas of the lower cranial nerves. Otol Neurotol; 2006 Dec;27(8):1142-5
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  • [Title] Intracranial schwannomas of the lower cranial nerves.
  • PATIENTS: All patients with intracranial lower cranial nerve schwannomas treated surgically in our institution between July 1998 and July 2005.
  • INTERVENTION: A retrosigmoid, transcondylar, or combined approach was used for tumor recurrence.
  • RESULTS: Thirty-nine patients underwent surgical resection, with complete tumor removal in 32, near-total resection in 5 patients, and subtotal tumor excision in 2 patients.
  • Long-term (mean, 8.2 years) magnetic resonance imaging surveillance demonstrated recurrent tumor in 2 of 32 complete resections and slow regrowth in 2 of 7 patients with known residual disease.
  • DISCUSSION: Intracranial schwannomas of the lower cranial nerves are relatively uncommon and may present with subtle or no clinical symptoms.
  • Successful surgical resection with low risk of tumor recurrence can be achieved with the retrosigmoid or transcondylar approach.
  • [MeSH-major] Cranial Fossa, Posterior. Cranial Nerve Neoplasms / surgery. Neoplasm Recurrence, Local / surgery. Neurilemmoma / surgery. Skull Base Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Cerebral Angiography. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Otorhinolaryngologic Surgical Procedures. Reoperation. Retrospective Studies. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 17130803.001).
  • [ISSN] 1531-7129
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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73. Chacko G, Chacko AG, Dunham CP, Judkins AR, Biegel JA, Perry A: Atypical teratoid/rhabdoid tumor arising in the setting of a pleomorphic xanthoastrocytoma. J Neurooncol; 2007 Sep;84(2):217-22
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  • [Title] Atypical teratoid/rhabdoid tumor arising in the setting of a pleomorphic xanthoastrocytoma.
  • We present a case of a 23-year-old man with a tumor containing glial and rhabdoid elements where the former had features of a pleomorphic xanthoastrocytoma (PXA) and the latter had the immunophenotype and genetic profile of an atypical rhabdoid/teratoid tumor.
  • The patient presented with a short history of raised intracranial pressure with rapid deterioration in sensorium.
  • We speculate that the PXA was a quiescent tumor and that the secondary genetic alterations, including inactivation of the INI1 gene led to clinical progression.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Rhabdoid Tumor / pathology. Teratoma / pathology
  • [MeSH-minor] Adult. Chromosomal Proteins, Non-Histone / genetics. Chromosomes, Human, Pair 22 / genetics. DNA Mutational Analysis. DNA-Binding Proteins / genetics. Fatal Outcome. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Male. Point Mutation. SMARCB1 Protein. Transcription Factors / genetics

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  • (PMID = 17431546.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
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74. Reardon DA, Egorin MJ, Desjardins A, Vredenburgh JJ, Beumer JH, Lagattuta TF, Gururangan S, Herndon JE 2nd, Salvado AJ, Friedman HS: Phase I pharmacokinetic study of the vascular endothelial growth factor receptor tyrosine kinase inhibitor vatalanib (PTK787) plus imatinib and hydroxyurea for malignant glioma. Cancer; 2009 May 15;115(10):2188-98
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  • No patients developed intracranial hemorrhage.
  • Strategies to target tumor blood vessel endothelial cells and pericytes by inhibiting VEGFR and platelet-derived growth factor, respectively, were safe among recurrent malignant glioma patients and may enhance antiangiogenesis activity.

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  • (PMID = 19248046.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P50 CA108786; United States / NINDS NIH HHS / NS / 5P50-NS20023; United States / NCRR NIH HHS / RR / M01 RR 30; United States / NINDS NIH HHS / NS / P50 NS020023; United States / NCI NIH HHS / CA / 2P30 CA47904; United States / NCI NIH HHS / CA / P30 CA047904; United States / NINDS NIH HHS / NS / NS020023-250020; United States / NCI NIH HHS / CA / 5 R37 CA11898; United States / NCI NIH HHS / CA / 5 P50 CA 108786-4; United States / NINDS NIH HHS / NS / P50 NS020023-250020; United States / NCI NIH HHS / CA / R37 CA011898
  • [Publication-type] Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Benzamides; 0 / Phthalazines; 0 / Piperazines; 0 / Pyridines; 0 / Pyrimidines; 5DX9U76296 / vatalanib; 8A1O1M485B / Imatinib Mesylate; X6Q56QN5QC / Hydroxyurea
  • [Other-IDs] NLM/ NIHMS113633; NLM/ PMC2691174
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75. Podoreski D, Krolo I, Ivkić M, Marotti M, Kosović V, Visković K: Magnetic resonance imaging in the diagnosis of malignant tumors of the maxillofacial region. Acta Clin Croat; 2010 Mar;49(1):33-41
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  • This imaging method was evaluated for the ability to detect tumor location and to analyze dimensions and structure of the tumor, bone involvement, effect on neurovascular structures and extension to soft tissues.
  • The sensitivity for tumor location was 94.4%, tumor necrosis 93%, hemorrhage 93.3% and bone involvement 91.4%.
  • The specificity for tumor location was 84%, tumor necrosis 92.8%, hemorrhage 92.8% and bone involvement 85.7%.
  • In the evaluation of soft tissue tumor extension to bone structures, MRI sensitivity and specificity was 94.4% and 88.2%, respectively.
  • The sensitivity for perineural infiltration and tumor involvement of vascular structures was 91% and 91.6%, respectively.
  • The specificity for perineural infiltration was 96.7% and for tumor involvement of vascular structures 88%.
  • MRI sensitivity and specificity for intracranial extension, intraorbital propagation, extension to pterygopalatine fossa and other surrounding anatomic spaces was 93.5% and 90.9%, respectively.
  • Study results demonstrated MRI to provide valuable information in the analysis of tumor structure, bone involvement and extension to soft tissues of malignant tumors of the maxillofacial region.
  • [MeSH-major] Jaw Neoplasms / diagnosis. Magnetic Resonance Imaging. Nose Neoplasms / diagnosis. Paranasal Sinus Neoplasms / diagnosis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Sensitivity and Specificity. Young Adult

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  • (PMID = 20635582.001).
  • [ISSN] 0353-9466
  • [Journal-full-title] Acta clinica Croatica
  • [ISO-abbreviation] Acta Clin Croat
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Croatia
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76. Bikmaz K, Mrak R, Al-Mefty O: Management of bone-invasive, hyperostotic sphenoid wing meningiomas. J Neurosurg; 2007 Nov;107(5):905-12
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  • OBJECT: The hyperostosis frequently associated with sphenoid wing meningiomas is actual invasion of bone by the tumor.
  • The intracranial portion of the tumor is usually thin with en plaque spread, and the tumor tends to invade the orbit through the superior orbital fissure.
  • Seventeen of the patients had the distinguishing characteristics of hyperostotic sphenoid wing meningiomas-extensive bone invasion, en plaque dural involvement, and a minimal intracranial mass with minimal orbital involvement.
  • [MeSH-major] Hyperostosis / pathology. Meningeal Neoplasms / pathology. Meningeal Neoplasms / surgery. Meningioma / surgery. Neoplasm Invasiveness / pathology. Orbit / pathology
  • [MeSH-minor] Adult. Aged. Dura Mater / surgery. Female. Follow-Up Studies. Humans. Ki-67 Antigen / analysis. Male. Middle Aged. Neoplasm Recurrence, Local. Receptors, Estrogen / analysis. Receptors, Progesterone / analysis. Treatment Outcome

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  • (PMID = 17977259.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Ki-67 Antigen; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
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77. Sun Y, Mao YP, Ma J, Huang Y, Tang LL, Wang Y, Liu LZ, Lu TX: [Influences of magnetic resonance imaging on the staging system of nasopharyngeal carcinoma]. Ai Zheng; 2007 Feb;26(2):158-63
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  • RESULTS: MRI was better than CT in detecting the invasion of NPC in the extra-nasopharyngeal cavity (the oropharyrnx, nasal cavity, and parapharyngeal spatium), retropharyngeal lymph node, base of skull, paranasal sinuses, intracranial cavernous sinus, infratemporal fossa, and cervical vertebra.
  • CONCLUSIONS: Compared with CT, MRI has a remarkable advantage in detecting the primary tumor extension of NPC, but has no advantage in detecting cervical lymph node metastasis.
  • [MeSH-major] Magnetic Resonance Imaging. Nasopharyngeal Neoplasms / pathology. Neoplasm Staging / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Lymph Nodes / pathology. Male. Middle Aged. Nasal Cavity / pathology. Nasopharynx / pathology. Neoplasm Invasiveness. Oropharynx / pathology. Paranasal Sinuses / pathology. Tomography, Spiral Computed. Young Adult


78. Achrol AS, Kim H, Pawlikowska L, Trudy Poon KY, McCulloch CE, Ko NU, Johnston SC, McDermott MW, Zaroff JG, Lawton MT, Kwok PY, Young WL: Association of tumor necrosis factor-alpha-238G&gt;A and apolipoprotein E2 polymorphisms with intracranial hemorrhage after brain arteriovenous malformation treatment. Neurosurgery; 2007 Oct;61(4):731-9; discussion 740
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  • [Title] Association of tumor necrosis factor-alpha-238G>A and apolipoprotein E2 polymorphisms with intracranial hemorrhage after brain arteriovenous malformation treatment.
  • OBJECTIVE: We previously reported specific genotypes of polymorphisms in two genes, tumor necrosis factor-alpha (TNF-alpha-238G > A) and Apolipoprotein E (ApoE e2), as independent predictors of new intracranial hemorrhage (ICH) in the natural course of untreated brain arteriovenous malformations.

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  • (PMID = 17986934.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] ENG
  • [Grant] United States / NINDS NIH HHS / NS / P01 NS44155; United States / NINDS NIH HHS / NS / P01 NS044155; United States / NINDS NIH HHS / NS / K23 NS044014-05; United States / NINDS NIH HHS / NS / K23 NS044014; United States / NINDS NIH HHS / NS / R01 NS041877; United States / NINDS NIH HHS / NS / R01 NS41877; United States / NINDS NIH HHS / NS / NS044014-05; United States / NINDS NIH HHS / NS / R01 NS034949; United States / NINDS NIH HHS / NS / R01 NS34949
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Apolipoprotein E2; 0 / Tumor Necrosis Factor-alpha
  • [Other-IDs] NLM/ NIHMS48409; NLM/ PMC4648368
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79. Zhang HZ, Lan Q: Design and microsurgical anatomy of the retrosigmoid-retrocondylar keyhole approach without occipital condyle removal. Minim Invasive Neurosurg; 2006 Feb;49(1):49-54
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  • METHODS: 8 adult cadaveric heads fixed in formalin and with intracranial vessels perfused by colored latex were used in this study.
  • With the techniques of modern microsurgery, several diseases such as an aneurysm situated at the vertebral artery or the posterior inferior cerebellar artery, a small hypoglossal neurinoma and tumor located at the ventral lateral aspect of the medulla oblongata, may be operated via this retrosigmoid-retrocondylar keyhole approach without drilling the occipital condyle.
  • [MeSH-minor] Adult. Cadaver. Cranial Nerves / anatomy & histology. Dissection. Feasibility Studies. Humans. Medulla Oblongata / anatomy & histology. Vertebral Artery / anatomy & histology

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  • (PMID = 16547883.001).
  • [ISSN] 0946-7211
  • [Journal-full-title] Minimally invasive neurosurgery : MIN
  • [ISO-abbreviation] Minim Invasive Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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80. Pereira-Neto A, Borba AM, Mello PA, Naves LA, Araújo Jr AS, Casulari LA: Mean intrasellar pressure, visual field, headache intensity and quality of life of patients with pituitary adenoma. Arq Neuropsiquiatr; 2010 Jun;68(3):350-4
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  • These data were correlated with serum prolactin levels, number of visual quadrant affected, tumor size, quality of life (measured through the SF-36 scale) and graded headache (measured through the HIT-6 scale).
  • [MeSH-major] Adenoma / complications. Headache / etiology. Pituitary Neoplasms / complications. Quality of Life / psychology. Visual Fields / physiology
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Intracranial Pressure / physiology. Male. Middle Aged. Pressure. Severity of Illness Index. Young Adult

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  • (PMID = 20602034.001).
  • [ISSN] 1678-4227
  • [Journal-full-title] Arquivos de neuro-psiquiatria
  • [ISO-abbreviation] Arq Neuropsiquiatr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
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81. Gasco J, Franklin B, Rangel-Castilla L, Campbell GA, Eltorky M, Salinas P: Infratentorial angioleiomyoma: a new location for a rare neoplastic entity. J Neurosurg; 2009 Apr;110(4):670-4
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  • Angioleiomyomas are benign neoplasms most often located in the subcutaneous tissue of middle-aged individuals and usually confined to the subcuticular and deep dermal layers of the lower extremities.
  • An intracranial site for this tumor is exceedingly rare, with very few reports documenting locations in the neuraxis.
  • The authors conducted a review of selected English-language papers published since 1960 describing well-documented cases of intracranial vascular leiomyomas, with detailed information on the clinical presentation, radiology, pathology, and particulars of surgical management in each case.
  • [MeSH-major] Brain Neoplasms / pathology
  • [MeSH-minor] Adult. Angiomyoma / pathology. Angiomyoma / radiography. Humans. Magnetic Resonance Imaging. Male. Tomography, X-Ray Computed

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  • (PMID = 19012476.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 17
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82. Merrell R, Nabors LB, Perry A, Palmer CA: 1p/19q chromosome deletions in metastatic oligodendroglioma. J Neurooncol; 2006 Nov;80(2):203-7
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  • Although the bone metastasis was non-informative, the primary intracranial tumor revealed codeletions of the 1p and 19q chromosomal arms, commonly recognized as the genetically favorable profile of oligodendrogliomas.
  • Both patients died of complications related to their systemic disease and did not have any radiologic evidence of intracranial progression at the time of their last MRI studies.
  • [MeSH-major] Bone Marrow Neoplasms / genetics. Bone Marrow Neoplasms / secondary. Bone Neoplasms / genetics. Bone Neoplasms / secondary. Brain Neoplasms / pathology. Chromosome Deletion. Chromosomes, Human, Pair 1 / genetics. Chromosomes, Human, Pair 19 / genetics. Oligodendroglioma / genetics. Oligodendroglioma / secondary. Spinal Neoplasms / genetics. Spinal Neoplasms / secondary
  • [MeSH-minor] Adult. Aged. Fatal Outcome. Female. Humans. In Situ Hybridization. Magnetic Resonance Imaging. Male. Tomography, X-Ray Computed

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  • (PMID = 16710746.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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83. Schroeder TM, Chintagumpala M, Okcu MF, Chiu JK, Teh BS, Woo SY, Paulino AC: Intensity-modulated radiation therapy in childhood ependymoma. Int J Radiat Oncol Biol Phys; 2008 Jul 15;71(4):987-93
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  • PURPOSE: To determine the patterns of failure after intensity-modulated radiation therapy (IMRT) for localized intracranial ependymoma.
  • METHODS AND MATERIALS: From 1994 to 2005, 22 children with pathologically proven, localized, intracranial ependymoma were treated with adjuvant IMRT.
  • Of the patients, 12 (55%) had an infratentorial tumor and 14 (64%) had anaplastic histology.
  • The clinical target volume encompassed the tumor bed and any residual disease plus margin (median dose 54 Gy).
  • [MeSH-major] Brain Neoplasms / radiotherapy. Ependymoma / radiotherapy. Neoplasm Recurrence, Local / prevention & control. Neoplasm Recurrence, Local / radiotherapy. Radiotherapy, Conformal / methods
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Dose-Response Relationship, Radiation. Female. Humans. Infant. Male. Radiotherapy Dosage. Retrospective Studies. Treatment Outcome

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  • (PMID = 18258381.001).
  • [ISSN] 0360-3016
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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84. Gergont A, Biedroń A, Zajac A, Steczkowska M: [Causes and diagnostics of dizziness of central origin in children]. Przegl Lek; 2009;66(11):983-7
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  • Vertigo of central origin in children can be a first symptom of severe conditions, such as tumor of CNS, therefore the neuroradiological evaluation is necessary for early diagnosis, before the occurrence of increase of intracranial pressure symptoms.
  • [MeSH-minor] Adult. Borrelia Infections / complications. Borrelia Infections / diagnosis. Cerebrovascular Disorders / complications. Cerebrovascular Disorders / diagnosis. Child. Diagnosis, Differential. Electroencephalography. Evoked Potentials. Humans. Serologic Tests

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  • (PMID = 20297643.001).
  • [ISSN] 0033-2240
  • [Journal-full-title] Przegla̧d lekarski
  • [ISO-abbreviation] Prz. Lek.
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Poland
  • [Number-of-references] 27
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85. Looi A, Kazim M, Cortes M, Rootman J: Orbital reconstruction after eyelid- and conjunctiva-sparing orbital exenteration. Ophthal Plast Reconstr Surg; 2006 Jan-Feb;22(1):1-6
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  • Average follow-up period was 21 months, during which one patient had development of intracranial meningioma at the proximal end of the optic canal.
  • Case selection is emphasized, as this technique is mainly reserved for histopathologically benign orbital lesions that exhibit local aggressive behavior and for malignant lesions only if there is no eyelid, lacrimal gland, or orbital fissure involvement nor significant conjunctival or deep extension of an intraocular tumor.
  • [MeSH-minor] Adult. Aged. Child. Eye Neoplasms / surgery. Female. Follow-Up Studies. Humans. Male. Retrospective Studies

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  • (PMID = 16418657.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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86. Mitsuyama T, Ide M, Hagiwara S, Tanaka N, Kawamura H, Aiba M: [Adult choroid plexus papilloma of the posterior fossa: extraventricular location]. No Shinkei Geka; 2005 Aug;33(8):825-9
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  • [Title] [Adult choroid plexus papilloma of the posterior fossa: extraventricular location].
  • Choroid plexus papillomas (CPPs) are rare neuroectodermal neoplasms accounting for 0.4% of all intracranial neoplasms in adults.
  • It is difficult to diagnose CPP preoperatively when the main portion of the tumor is not located in the 4th ventricle.
  • Magnetic resonance imaging demonstrated an intracerebellar solid tumor with multilocular cysts, extending towards both the right lateral medullary region and the foramen of Luschka.
  • Angiographically, via the right posterior inferior cerebellar artery revealed the tumor was faintly opacified.
  • Tumor was subtotally resected through a right suboccipital craniectomy.
  • CPP should be considered among calcified and enhanced masses in the lateral medullary to cerebellopontine angle space in adults, even if the main portion of the tumor is not located in the 4th ventricle.
  • [MeSH-major] Infratentorial Neoplasms / surgery. Papilloma, Choroid Plexus / surgery

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  • [ErratumIn] No Shinkei Geka. 2005 Oct;33(10):977
  • (PMID = 16095214.001).
  • [ISSN] 0301-2603
  • [Journal-full-title] No shinkei geka. Neurological surgery
  • [ISO-abbreviation] No Shinkei Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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87. Maier-Hauff K, Rothe R, Scholz R, Gneveckow U, Wust P, Thiesen B, Feussner A, von Deimling A, Waldoefner N, Felix R, Jordan A: Intracranial thermotherapy using magnetic nanoparticles combined with external beam radiotherapy: results of a feasibility study on patients with glioblastoma multiforme. J Neurooncol; 2007 Jan;81(1):53-60
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  • [Title] Intracranial thermotherapy using magnetic nanoparticles combined with external beam radiotherapy: results of a feasibility study on patients with glioblastoma multiforme.
  • The actually achieved magnetic fluid distribution was measured by computed tomography (CT), which after matching to pre-operative MRI data enables the calculation of the expected heat distribution within the tumor in dependence of the magnetic field strength.
  • Patients received 4-10 (median: 6) thermotherapy treatments following instillation of 0.1-0.7 ml (median: 0.2) of magnetic fluid per ml tumor volume and single fractions (2 Gy) of a radiotherapy series of 16-70 Gy (median: 30).
  • Median maximum intratumoral temperatures of 44.6 degrees C (42.4-49.5 degrees C) were measured and signs of local tumor control were observed.
  • [MeSH-major] Brain Neoplasms / therapy. Glioblastoma / therapy. Hyperthermia, Induced / methods. Nanoparticles / therapeutic use. Radiotherapy / methods
  • [MeSH-minor] Adult. Aged. Combined Modality Therapy. Disease-Free Survival. Female. Humans. Magnetic Resonance Imaging. Magnetics / therapeutic use. Male. Middle Aged

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  • (PMID = 16773216.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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88. Ryou KS, Lee SH, Park SH, Park J, Hwang SK, Hamm IS: Multiple fusiform myxomatous cerebral aneurysms in a patient with Carney complex. J Neurosurg; 2008 Aug;109(2):318-20
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  • Carney complex is a rare autosomal-dominant familial tumor syndrome that involves the triad of myxoma, mucocutaneous pigmentation, and endocrine overactivity.
  • [MeSH-major] Heart Neoplasms / complications. Intracranial Aneurysm / etiology. Intracranial Aneurysm / radiography. Myxoma / complications
  • [MeSH-minor] Adenoma / complications. Adult. Aneurysm / etiology. Aneurysm / radiography. Cerebral Angiography. Female. Heart Atria. Humans. Pituitary Neoplasms / complications

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  • (PMID = 18671646.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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89. Tao Y, Wei Q, Xu Z, Bai R, Li Y, Luo C, Dong Y, Gao G, Lu Y: Holistic and network analysis of meningioma pathogenesis and malignancy. Biofactors; 2006;28(3-4):203-19
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  • Meningiomas, which originate from arachnoid cells and constitute the largest subgroup of all intracranial tumors, are generally benign, yet have the capacity to progress into a higher histological grade of malignancy associated with an increase in biological aggressivity and/or capacity to recur.
  • [MeSH-major] Biomarkers, Tumor / analysis. Meningioma / chemistry. Meningioma / pathology. Proteome / chemistry
  • [MeSH-minor] Adolescent. Adult. Aged. Antigens, CD29 / genetics. Child. Child, Preschool. China / epidemiology. Down-Regulation. Female. Gene Expression Regulation, Neoplastic. Gene Products, tat / metabolism. Humans. Immunoblotting. Male. Middle Aged. Oligonucleotide Array Sequence Analysis. Sex Factors. Thioredoxins / analysis. Up-Regulation

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  • (PMID = 17473381.001).
  • [ISSN] 0951-6433
  • [Journal-full-title] BioFactors (Oxford, England)
  • [ISO-abbreviation] Biofactors
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antigens, CD29; 0 / Biomarkers, Tumor; 0 / Gene Products, tat; 0 / Proteome; 52500-60-4 / Thioredoxins
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90. Manon R, O'Neill A, Knisely J, Werner-Wasik M, Lazarus HM, Wagner H, Gilbert M, Mehta M, Eastern Cooperative Oncology Group: Phase II trial of radiosurgery for one to three newly diagnosed brain metastases from renal cell carcinoma, melanoma, and sarcoma: an Eastern Cooperative Oncology Group study (E 6397). J Clin Oncol; 2005 Dec 1;23(34):8870-6
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  • On the basis of tumor size, patients received 24, 18, or 15 Gy RS.
  • The primary end point was 3- and 6-month intracranial progression.
  • Three- and 6-month intracranial failure with RS alone was 25.8% and 48.3%.
  • Failure within and outside the RS volume, when in-field and distant intracranial failures were scored independently, was 19.3% and 16.2% (3 months) and 32.2% and 32.2% (6 months), respectively.
  • CONCLUSION: Intracranial failure rates without WBRT were 25.8% and 48.3% at 3 and 6 months, respectively.
  • [MeSH-major] Brain Neoplasms / secondary. Brain Neoplasms / surgery. Radiosurgery / methods
  • [MeSH-minor] Adult. Brain / pathology. Brain / physiopathology. Brain / surgery. Carcinoma, Renal Cell / secondary. Carcinoma, Renal Cell / surgery. Cognition / physiology. Female. Follow-Up Studies. Humans. Kidney Neoplasms / pathology. Male. Melanoma / pathology. Neoplasm Recurrence, Local. Neoplasm Staging. Prospective Studies. Sarcoma / pathology. Survival Analysis. Survival Rate. Time Factors. Treatment Outcome

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  • (PMID = 16314647.001).
  • [ISSN] 0732-183X
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase II; Journal Article
  • [Publication-country] United States
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91. Noshita N, Fujimura M, Kumabe T, Shirane R, Watanabe M, Tominaga T: A case of cellular blue naevus with intracranial invasion and malignant transformation. Acta Neurochir (Wien); 2005 Feb;147(2):211-3; discussion 213
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  • [Title] A case of cellular blue naevus with intracranial invasion and malignant transformation.
  • [MeSH-major] Brain Neoplasms / complications. Cell Transformation, Neoplastic / pathology. Melanoma / complications. Meningeal Neoplasms / complications. Neoplasms, Second Primary / complications. Nevus, Blue / complications
  • [MeSH-minor] Adult. Biomarkers, Tumor / metabolism. Cavernous Sinus / pathology. Cavernous Sinus / physiopathology. Dura Mater / pathology. Dura Mater / physiopathology. Humans. Magnetic Resonance Imaging. Male. Neoplasm Invasiveness. Neurosurgical Procedures. Orbit / pathology. Orbit / physiopathology. Sphenoid Bone / pathology. Sphenoid Bone / physiopathology. Treatment Outcome

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  • (PMID = 15647890.001).
  • [ISSN] 0001-6268
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Austria
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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92. Huang QH, Yang K, Cai X, Wang ZZ, Ma CY, Shun BY, Chen ZG: [Endovascular embolization and microsurgical operation treatment of intracranial anterior circulation aneurysms]. Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2008 Nov;33(11):1050-2
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  • [Title] [Endovascular embolization and microsurgical operation treatment of intracranial anterior circulation aneurysms].
  • OBJECTIVE: To explore the surgical treatment and effect of intracranial anterior circulation aneurysms.
  • METHODS: Thirty-eight patients with intracranial anterior circulation aneurysms were enrolled, 9 were treated with endovascular embolization,and 29 with pterion approach micro-euthyphoria operation.
  • CONCLUSION: Surgical treatment of intracranial anterior circulation aneurysms is the first choice to help blood tumor cleaning-up and intracranial pressure degrading.
  • [MeSH-major] Embolization, Therapeutic / methods. Intracranial Aneurysm / surgery. Microsurgery / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Female. Humans. Male. Middle Aged. Young Adult

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  • (PMID = 19060375.001).
  • [ISSN] 1672-7347
  • [Journal-full-title] Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
  • [ISO-abbreviation] Zhong Nan Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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93. Andrade-Souza YM, Zadeh G, Ramani M, Scora D, Tsao MN, Schwartz ML: Testing the radiosurgery-based arteriovenous malformation score and the modified Spetzler-Martin grading system to predict radiosurgical outcome. J Neurosurg; 2005 Oct;103(4):642-8
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  • The median tumor margin dose was 15 Gy (mean 17.23 Gy, range 15-25 Gy).
  • [MeSH-major] Intracranial Arteriovenous Malformations / classification. Intracranial Arteriovenous Malformations / surgery. Radiosurgery / methods
  • [MeSH-minor] Adolescent. Adult. Age Factors. Aged. Child. Female. Humans. Male. Middle Aged. Predictive Value of Tests. Prognosis. Severity of Illness Index. Treatment Outcome

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  • (PMID = 16266046.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article; Validation Studies
  • [Publication-country] United States
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94. Anton T, Guttierez J, Rock J: Tentorial schwannoma: a case report and review of the literature. J Neurooncol; 2006 Feb;76(3):307-11
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  • Unusual locations for intracranial schwannomas have also been reported in association with neurofibromatosis.
  • Magnetic resonance imaging revealed a large tentorial-based tumor.
  • At surgery the origin of the tumor was clearly the tentorium, and while the trigeminal nerve was displaced, it easily separated from the mass.
  • CONCLUSION: While there are few reported cases of tentorial-based schwannoma, these tumors have been noted in unusual locations within the intracranial vault, and clinicians should be aware of this diversity of origin.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Dura Mater / pathology. Neurilemmoma / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. Meningioma / pathology. Neurosurgical Procedures. Tomography, X-Ray Computed. Trigeminal Nerve / pathology

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  • (PMID = 16200344.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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95. Li X, Yu RT, Xu K, Li FC, Fan YC, Gao WC, Guo KQ, Pan X, Yang C: [Application of diffusion tensor imaging in preoperation and postoperation patients of glioma with 3.0 Tesla MRI]. Zhonghua Yi Xue Za Zhi; 2009 May 19;89(19):1300-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Mean diffusivity (MD) and fractional anisotropy (FA) values were measured in regions of solid tumor, surrounding edema and normal white matter of the high grade cerebral gliomas.
  • Anatomic relationship between intracranial tumors and surrounding fibers was analysed on fractional anisotropic (FA) map, color-coded directional map, three-dimensional white matter tractography.
  • RESULTS: The DTI patterns altered by the tumor were categorized as follows: displacement, infiltration and destruction.
  • Apparently significant differences of MD were found in solid tumor, surrounding edema, compared with normal white matter regions (P < 0.05).
  • But there was no significant difference among solid tumor and surrounding edema region (P > 0.05).
  • There were significant differences of FA between solid tumor, surrounding edema and normal white matter region (P < 0.05).
  • MD and FA values could be used to distinguish normal white matter from solid tumor and surrounding edema region of high grade glioma.
  • [MeSH-major] Brain Neoplasms / diagnosis. Diffusion Magnetic Resonance Imaging. Glioma / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Humans. Male. Middle Aged. Neoplasm Staging. Prognosis. Young Adult

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  • (PMID = 19615179.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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96. Wang X, Cai BW, You C, He M: Microsurgical management of lateral ventricular meningiomas: a report of 51 cases. Minim Invasive Neurosurg; 2007 Dec;50(6):346-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The most common presenting symptoms were related to the gradually increasing high cranial pressure (82.4%) rather than the location of the tumor.
  • [MeSH-major] Cerebral Ventricle Neoplasms / surgery. Lateral Ventricles / pathology. Lateral Ventricles / surgery. Meningioma / surgery. Neurosurgical Procedures / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Intracranial Hypertension / etiology. Intracranial Hypertension / physiopathology. Intracranial Hypertension / surgery. Magnetic Resonance Imaging. Male. Middle Aged. Postoperative Complications / etiology. Postoperative Complications / physiopathology. Postoperative Complications / prevention & control. Postoperative Hemorrhage / etiology. Postoperative Hemorrhage / physiopathology. Postoperative Hemorrhage / prevention & control. Retrospective Studies. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 18210357.001).
  • [ISSN] 0946-7211
  • [Journal-full-title] Minimally invasive neurosurgery : MIN
  • [ISO-abbreviation] Minim Invasive Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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97. Kim IY, Niranjan A, Kondziolka D, Flickinger JC, Lunsford LD: Gamma knife radiosurgery for treatment resistant choroid plexus papillomas. J Neurooncol; 2008 Oct;90(1):105-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • These six patients had a total of 11 locally or distant recurrent intracranial tumors.
  • The median and mean tumor volumes were 2.7 and 3.9 cc (range, 0.23-21.1).
  • A median margin dose of 12.0 Gy (range, 11.5-15) was prescribed to the tumor margin.
  • At the second GKR, the tumor volume varied from 1.3 to 12.4 cc, and the marginal radiation dose varied from 11 to 14 Gy.
  • [MeSH-major] Brain Neoplasms / surgery. Neoplasm Recurrence, Local / surgery. Papilloma, Choroid Plexus / surgery
  • [MeSH-minor] Adult. Aged. Disease-Free Survival. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Radiosurgery

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  • (PMID = 18587534.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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98. Uematsu Y, Owai Y, Okita R, Tanaka Y, Itakura T: The usefulness and problem of intraoperative rapid diagnosis in surgical neuropathology. Brain Tumor Pathol; 2007;24(2):47-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • There were 180 cases of intracranial lesions excluding pituitary lesions.
  • [MeSH-major] Brain / surgery. Brain Neoplasms / diagnosis. Brain Neoplasms / surgery. Frozen Sections. Intraoperative Care / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Female. Humans. Infant. Intraoperative Period. Male. Middle Aged. Neurosurgical Procedures. Reproducibility of Results. Retrospective Studies

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  • (PMID = 18095130.001).
  • [ISSN] 1433-7398
  • [Journal-full-title] Brain tumor pathology
  • [ISO-abbreviation] Brain Tumor Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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99. Kim IY, Jung S, Jung TY, Kang SS, Moon KS, Joo SP: Intracranial tuberculoma with adjacent inflammatory aneurysms. J Clin Neurosci; 2008 Oct;15(10):1174-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intracranial tuberculoma with adjacent inflammatory aneurysms.
  • We describe for the first time a case of intracranial tuberculoma with adjacent intracerebral inflammatory aneurysms, and include a brief discussion of the developmental mechanism of these pathologies.
  • [MeSH-major] Brain Diseases / pathology. Intracranial Aneurysm / etiology. Parietal Lobe / pathology. Tuberculoma, Intracranial / complications
  • [MeSH-minor] Adult. Aneurysm, Infected / etiology. Aneurysm, Infected / therapy. Female. Humans. Inflammation / complications. Treatment Outcome

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  • (PMID = 18706816.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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100. Yokoi K, Akiyama M, Yanagisawa T, Yoshino M, Nakazaki H, Takahashi K, Takahashi-Fujigasaki J, Kanetsuna Y, Yamada H, Oi S, Eto Y: RNA expression analysis of a congenital intracranial teratoma. Pediatr Blood Cancer; 2005 May;44(5):516-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] RNA expression analysis of a congenital intracranial teratoma.
  • Congenital intracranial tumors are extremely rare and account only for 0.5%-1.5% of brain tumors in children.
  • We report a large intrauterine congenital teratoma in a female fetus at gestation weeks 37, which was diagnosed by detecting the tumor and associated craniomegaly with ultrasonography (US) and magnetic resonance (MR) imaging.
  • The tumor had replaced the cerebral hemispheres and produced prenatal manifestations.
  • [MeSH-major] Brain Neoplasms / diagnosis. Gene Expression Regulation, Neoplastic. Teratoma / diagnosis
  • [MeSH-minor] Adult. Diagnostic Imaging. Female. Fetal Diseases / diagnosis. Fetus. Gene Expression Profiling. Humans. Oligonucleotide Array Sequence Analysis. Pregnancy. RNA, Neoplasm / analysis

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  • (PMID = 15558703.001).
  • [ISSN] 1545-5009
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / RNA, Neoplasm
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