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76. Scottish Bone Tumor Registry, Sharma H, Mehdi SA, MacDuff E, Reece AT, Jane MJ, Reid R: Paget sarcoma of the spine: Scottish Bone Tumor Registry experience. Spine (Phila Pa 1976); 2006 May 20;31(12):1344-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Paget sarcoma of the spine: Scottish Bone Tumor Registry experience.
  • STUDY DESIGN: Retrospective case study of 13 cases of Paget sarcoma of the spine accrued from a prospectively collected Tumor Registry database.
  • OBJECTIVES: To analyze the clinical, radiologic, and histologic features of Paget sarcoma of the spine and to determine the factors influencing the prognosis.
  • There is very little in the literature with regard to clinical presentation and prognosis of patients with Paget sarcoma affecting the vertebral column.
  • METHODS: Between January 1944 and December 2003, 89 patients were registered with a diagnosis of Paget sarcoma in the Scottish Bone Tumor Registry.
  • Thirteen patients with Paget sarcoma of the spine were analyzed with regard to their clinical, radiologic, and histopathologic features along with the prognostic predictors.
  • The rest were chondrosarcoma (n = 1), fibrosarcoma (n = 1), and malignant fibrous histiocytoma (n = 1).
  • CONCLUSIONS: This series confirmed that Paget sarcoma of the spine has a very poor prognosis.
  • There was no significant difference observed on the overall prognosis of the patients with Paget sarcoma of the spine in the last 6 decades.
  • [MeSH-major] Lumbar Vertebrae. Osteitis Deformans. Sacrum. Sarcoma. Spinal Neoplasms
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Nerve Compression Syndromes / complications. Nerve Compression Syndromes / etiology. Nervous System Diseases / etiology. Registries. Retrospective Studies. Spinal Cord Compression / complications. Spinal Cord Compression / etiology. Spinal Nerve Roots. Survival Analysis. Tomography, X-Ray Computed


77. Jakowski JD, Wakely PE Jr: Primary intrathoracic low-grade fibromyxoid sarcoma. Hum Pathol; 2008 Apr;39(4):623-8
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  • [Title] Primary intrathoracic low-grade fibromyxoid sarcoma.
  • Low-grade fibromyxoid sarcoma (LGFMS) is a rare neoplasm commonly affecting young adults and typically arising in the somatic soft tissue of the proximal extremities.
  • Diagnosis was aided by a strikingly characteristic light microscopic appearance of a bland spindle cell sarcoma containing numerous so-called giant collagen rosettes and supported by immunohistology, evidence of FUS translocation by fluorescence in situ hybridization, and electron microscopy demonstrating a fibroblastic phenotype.
  • Low-grade fibromyxoid sarcoma is probably an underrecognized intrathoracic neoplasm and should be considered in the differential diagnosis of spindle cell neoplasms of the mediastinum, pleura, heart, and lungs.
  • [MeSH-major] Fibrosarcoma / diagnosis. Heart Neoplasms / diagnosis
  • [MeSH-minor] Adult. Female. Humans. In Situ Hybridization, Fluorescence. Male. Microscopy, Electron. Middle Aged. RNA-Binding Protein FUS / genetics. Translocation, Genetic

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  • [CommentIn] Hum Pathol. 2008 Oct;39(10):1553-4; author reply 1554 [18774378.001]
  • (PMID = 18275982.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / RNA-Binding Protein FUS
  • [Number-of-references] 30
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78. Kleinerman RA, Tucker MA, Abramson DH, Seddon JM, Tarone RE, Fraumeni JF Jr: Risk of soft tissue sarcomas by individual subtype in survivors of hereditary retinoblastoma. J Natl Cancer Inst; 2007 Jan 3;99(1):24-31
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  • [Title] Risk of soft tissue sarcomas by individual subtype in survivors of hereditary retinoblastoma.
  • BACKGROUND: Survivors of hereditary retinoblastoma have an increased risk for second malignancies, especially soft tissue sarcomas.
  • However, the risks of individual histologic subtypes of soft tissue sarcomas have not been evaluated.
  • METHODS: We estimated the risk for six subtypes of soft tissue sarcomas (fibrosarcoma, liposarcoma, histiocytoma, leiomyosarcoma, rhabdomyosarcoma, and others) in a cohort of 963 one-year survivors of hereditary retinoblastoma among patients diagnosed at two US institutions from 1914 through 1984.
  • We calculated standardized incidence ratios (SIRs) for specific subtypes of soft tissue sarcomas by comparison with population data from the Connecticut Tumor Registry or from National Cancer Institute Surveillance, Epidemiology, and End Results database.
  • We also calculated the cumulative risk for all soft tissue sarcomas combined.
  • RESULTS: We observed 69 soft tissue sarcomas in 68 patients with hereditary retinoblastoma.
  • Risks were elevated for soft tissue sarcomas overall (SIR = 184, 95% confidence interval [CI] = 143 to 233) and for individual subtypes.
  • Among patients treated with radiotherapy for retinoblastoma, we found statistically significantly increased risks of soft tissue sarcomas in the field of radiation.
  • Irradiated patients also had increased risks of soft tissue sarcomas, especially leiomyosarcomas, outside the field of radiation, and risks of soft tissue sarcomas were increased in nonirradiated patients as well, indicating a genetic predisposition to soft tissue sarcomas independent of radiation.
  • The cumulative risk for any soft tissue sarcoma 50 years after radiotherapy for retinoblastoma was 13.1% (95% CI = 9.7% to 17.0%).
  • CONCLUSION: Long-term follow-up of a cohort of survivors of hereditary retinoblastoma revealed a statistically significant excess of leiomyosarcoma and other soft tissue sarcomas that persists decades after the retinoblastoma diagnosis.
  • Retinoblastoma survivors should undergo regular medical surveillance for sarcomas in their adult years.
  • [MeSH-major] Neoplasms, Second Primary / epidemiology. Neoplasms, Second Primary / etiology. Population Surveillance. Retinoblastoma / genetics. Sarcoma / epidemiology. Sarcoma / etiology. Survivors / statistics & numerical data
  • [MeSH-minor] Adult. Aged. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Chemotherapy, Adjuvant. Child. Child, Preschool. Confounding Factors (Epidemiology). Female. Humans. Incidence. Infant. Leiomyosarcoma / epidemiology. Leiomyosarcoma / etiology. Male. Middle Aged. Odds Ratio. Radiotherapy / adverse effects. Radiotherapy, Adjuvant / adverse effects. Registries. Retinal Neoplasms / genetics. Risk Assessment. SEER Program. United States / epidemiology

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  • [CommentIn] J Natl Cancer Inst. 2007 Jan 3;99(1):3-5 [17202103.001]
  • (PMID = 17202110.001).
  • [ISSN] 1460-2105
  • [Journal-full-title] Journal of the National Cancer Institute
  • [ISO-abbreviation] J. Natl. Cancer Inst.
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / /
  • [Publication-type] Journal Article; Multicenter Study; Research Support, N.I.H., Intramural
  • [Publication-country] United States
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79. Collini P, Sorensen PH, Patel S, Blay JY, Issels RD, Maki RG, Eriksson M, del Muro XG: Sarcomas with spindle cell morphology. Semin Oncol; 2009 Aug;36(4):324-37
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  • [Title] Sarcomas with spindle cell morphology.
  • In the days before the term "high-grade undifferentiated pleomorphic sarcoma" came into use, one of the most common sarcoma diagnoses was "malignant fibrous histiocytoma," and before that, in an era before immunohistochemistry, "fibrosarcoma" was used to describe most sarcomas.
  • "Spindle cell" is a descriptive phrase that denotes the cellular shape of many of the sarcomas encountered in the adult population.
  • As a result, they are usually treated differently from small round cell sarcomas, and have different biological characteristics than those tumors and sarcomas with epithelioid morphology.
  • As a very broad generalization, sarcomas with a spindle cell microscopic morphology occur in adults and are treated primarily with surgery and often adjuvant or neoadjuvant radiation as primary therapy.
  • In comparison to small round cell sarcomas such as Ewing sarcoma, the use of adjuvant chemotherapy remains controversial, and the sensitivity of these tumors to chemotherapy in the metastatic setting is highly variable.
  • In this article, we describe some of the clinical and biological characteristics of this group of sarcomas.
  • [MeSH-major] Sarcoma / pathology
  • [MeSH-minor] Chemotherapy, Adjuvant. Fibrosarcoma / genetics. Fibrosarcoma / pathology. Gene Fusion. Heat-Shock Response. Humans. Hyperthermia, Induced. Protein Kinase Inhibitors / therapeutic use. Sarcoma, Synovial / genetics. Sarcoma, Synovial / pathology. Translocation, Genetic

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  • (PMID = 19664493.001).
  • [ISSN] 0093-7754
  • [Journal-full-title] Seminars in oncology
  • [ISO-abbreviation] Semin. Oncol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA47179
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Protein Kinase Inhibitors
  • [Number-of-references] 62
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80. Adeleye AO, Fellig Y, Umansky F, Shoshan Y: Rapid growth of primary cerebral fibrosarcoma with conversion to glioblastoma at second recurrence. J Neurooncol; 2009 Apr;92(2):233-8
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  • [Title] Rapid growth of primary cerebral fibrosarcoma with conversion to glioblastoma at second recurrence.
  • We present a case of de novo fibrosarcoma in a 43-year-old male, with MRI documented evolution from a 5 mm hyperintense area to 5 cm tumor mass in a 12-month period.
  • The diagnosis of low-grade fibrosarcoma was established by three experienced neuropathologists.
  • [MeSH-major] Brain Neoplasms / pathology. Fibrosarcoma / pathology. Glioblastoma / pathology. Neoplasms, Second Primary / pathology
  • [MeSH-minor] Adult. Combined Modality Therapy. Humans. Magnetic Resonance Imaging. Male. Neurosurgical Procedures. Radiosurgery. Radiotherapy, Conformal

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  • (PMID = 19082530.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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81. Willems SM, Debiec-Rychter M, Szuhai K, Hogendoorn PC, Sciot R: Local recurrence of myxofibrosarcoma is associated with increase in tumour grade and cytogenetic aberrations, suggesting a multistep tumour progression model. Mod Pathol; 2006 Mar;19(3):407-16
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  • A number of sarcomas are characterised by specific cytogenetic aberrations, giving not only insight in their biological pathways; they also serve as molecular markers in difficult diagnoses.
  • [MeSH-major] Chromosome Aberrations. Fibrosarcoma / pathology. Neoplasm Recurrence, Local / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Chromosome Banding. Disease Progression. Female. Humans. Karyotyping. Male. Middle Aged. Spectral Karyotyping

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  • (PMID = 16415793.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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82. He CY, Jin YL, Yang DM, Liu HG: [Clinicopathologic study of sinonasal inflammatory myofibroblastic tumor]. Zhonghua Bing Li Xue Za Zhi; 2010 Mar;39(3):166-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Actins / metabolism. Adult. Calcium-Binding Proteins / metabolism. Diagnosis, Differential. Female. Fibrosarcoma / pathology. Humans. Ki-67 Antigen / metabolism. Lymphatic Metastasis. Male. Microfilament Proteins / metabolism. Middle Aged. Neoplasm Recurrence, Local. Neurofibromatoses / pathology. Vimentin / metabolism

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  • (PMID = 20450762.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / ACTA2 protein, human; 0 / Actins; 0 / Calcium-Binding Proteins; 0 / Ki-67 Antigen; 0 / Microfilament Proteins; 0 / Vimentin; 0 / calponin
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83. Takahama A Jr, León JE, de Almeida OP, Kowalski LP: Nonlymphoid mesenchymal tumors of the parotid gland. Oral Oncol; 2008 Oct;44(10):970-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Four malignant tumors were classified as rhabdomyosarcoma, fibrosarcoma, Langerhans cell histiocytosis and endodermal sinus tumor.
  • From the malignant cases, only the patient with fibrosarcoma died due the tumor, the other three are alive with no signs of recurrence.
  • All cases were treated by surgery with no recurrences, except one case of fibrosarcoma whose patient died of distant metastasis.
  • [MeSH-minor] Adolescent. Adult. Aged. Brazil. Child. Child, Preschool. Diagnosis, Differential. Endodermal Sinus Tumor / pathology. Female. Fibrosarcoma / pathology. Histiocytosis, Langerhans-Cell / pathology. Humans. Infant. Male. Middle Aged. Neurofibroma / pathology. Rhabdomyosarcoma / pathology. Young Adult

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  • (PMID = 18282791.001).
  • [ISSN] 1879-0593
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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8
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4. Estep AL, Tidyman WE, Teitell MA, Cotter PD, Rauen KA: HRAS mutations in Costello syndrome: detection of constitutional activating mutations in codon 12 and 13 and loss of wild-type allele in malignancy. Am J Med Genet A; 2006 Jan 1;140(1):8-16
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • To gain an understanding of the relationship between constitutional HRAS mutations and malignancy, HRAS was sequenced in an advanced biphasic rhabdomyosarcoma/fibrosarcoma from an individual with a 34G --> A mutation.
  • [MeSH-minor] Adolescent. Adult. Alleles. Base Sequence. Cardiovascular Abnormalities / pathology. Child. Child, Preschool. Codon / genetics. Cohort Studies. DNA Mutational Analysis. Face / abnormalities. Genetic Predisposition to Disease / genetics. Genotype. Humans. Infant. Intellectual Disability / pathology. Musculoskeletal Abnormalities / pathology. Neoplasms / genetics. Phenotype. Skin Abnormalities / pathology. Syndrome


85. Coelho PN, Banazol NG, Soares RJ, Fragata JI: Long-term survival with heart transplantation for fibrosarcoma of the heart. Ann Thorac Surg; 2010 Aug;90(2):635-6
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  • [Title] Long-term survival with heart transplantation for fibrosarcoma of the heart.
  • Primary sarcoma of the heart is a rare disease that has an ominous prognosis with either medical or surgical therapy.
  • We report a case of a 25-year-old woman with sarcoma of the heart who received a transplant and is clinically well after 7 years.
  • [MeSH-major] Fibrosarcoma / surgery. Heart Neoplasms / surgery. Heart Transplantation
  • [MeSH-minor] Adult. Female. Humans. Survivors. Time Factors

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  • [Copyright] Copyright 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20667366.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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86. Zhang H, Wu D, Wang Z, Xu J, Wang H: Primary fibrosarcoma of the diaphragm with pleural effusion. Clin Respir J; 2010 Apr;4(2):127-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary fibrosarcoma of the diaphragm with pleural effusion.
  • [MeSH-major] Diaphragm / pathology. Fibrosarcoma / pathology. Fibrosarcoma / radiography. Pleural Effusion, Malignant / etiology. Thoracic Neoplasms / pathology. Thoracic Neoplasms / radiography
  • [MeSH-minor] Adult. Female. Humans. Tomography, X-Ray Computed

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  • (PMID = 20565488.001).
  • [ISSN] 1752-699X
  • [Journal-full-title] The clinical respiratory journal
  • [ISO-abbreviation] Clin Respir J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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87. Ayadi L, Charfi S, Khabir A, Kalle R, Sellami A, Makni S, Boudawara Z, Sellami-Boudawara T: [Cerebral gliosarcoma: clinico-pathologic study of 8 cases]. Tunis Med; 2010 Mar;88(3):142-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Sarcomatous component had features of fibrosarcoma in 5 cases, osteosarcoma in 2 cases and malignant fibrous histiocytoma in 1 case.
  • [MeSH-minor] Adult. Aged. Female. Follow-Up Studies. Humans. Male. Middle Aged. Radiotherapy, Adjuvant. Retrospective Studies


88. Sharma H, Jane MJ, Reid R: Scapulo-humeral Paget's sarcoma: Scottish Bone Tumour Registry experience. Eur J Cancer Care (Engl); 2005 Sep;14(4):367-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Scapulo-humeral Paget's sarcoma: Scottish Bone Tumour Registry experience.
  • This study aimed to analyse the clinical, radiological and histological features of 16 scapulo-humeral Paget's sarcoma cases accrued from Scottish Bone Tumour Registry between January 1950 and December 2000.
  • Histology showed predominantly osteosarcoma (n = 12), followed by pleomorphic sarcoma (n = 2), malignant fibrous histiocytoma (n = 1) and fibrosarcoma (n = 1).
  • In summary, Paget's sarcoma of the scapulo-humeral area presents with progressively worsening pain, a painful mass with or without a pathological fracture, predominantly lytic in humeral and purely sclerotic in scapular lesions, osteosarcoma-dominant histology, primarily treated with an early limb ablative surgery and associated with a poor 1-year survival (12.5%) and 5-year survival (6.2%) rate.
  • [MeSH-minor] Adult. Aged. Female. Humans. Humeral Fractures / pathology. Humeral Fractures / radiography. Humeral Fractures / surgery. Male. Middle Aged. Pain / physiopathology. Registries. Scotland. Survival Analysis


89. Eyden B: The myofibroblast: a study of normal, reactive and neoplastic tissues, with an emphasis on ultrastructure. part 2 - tumours and tumour-like lesions. J Submicrosc Cytol Pathol; 2005 Nov;37(3-4):231-96
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Ultrastructural features are described of nodular fasciitis, the myofibromatoses (including Dupuytren's disease), inflammatory myofibroblastic tumour, post-operative spindle cell nodule, fibroma of tendon sheath, fibrous pseudotumour, benign fibrous histiocytoma, atypical fibroxanthoma, dermatofibrosarcoma protuberans, myofibrosarcoma (myofibroblastic sarcoma), malignant fibrous histiocytoma (pleomorphic myofibrosarcoma), epithelioid sarcoma and spindle-cell carcinoma.
  • Fibrosarcoma and leiomyosarcoma are illustrated for comparison.
  • [MeSH-minor] Adolescent. Adult. Animals. Female. Humans. Male. Microscopy, Electron, Transmission

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  • (PMID = 16612972.001).
  • [ISSN] 1122-9497
  • [Journal-full-title] Journal of submicroscopic cytology and pathology
  • [ISO-abbreviation] J. Submicrosc. Cytol. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 344
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90. Heletz I, Abramson SV: Large obstructive cardiac myxofibrosarcoma is nearly invisible on transthoracic echocardiogram. Echocardiography; 2009 Aug;26(7):847-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Malignant primary cardiac tumors are exceptionally rare, and the most common of these are sarcomas.
  • [MeSH-major] Echocardiography / methods. Fibrosarcoma / ultrasonography. Heart Atria / ultrasonography. Heart Neoplasms / ultrasonography
  • [MeSH-minor] Adult. Diagnostic Errors / prevention & control. False Negative Reactions. Humans. Male

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  • (PMID = 19490014.001).
  • [ISSN] 1540-8175
  • [Journal-full-title] Echocardiography (Mount Kisco, N.Y.)
  • [ISO-abbreviation] Echocardiography
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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91. Berkmann S, Tolnay M, Hänggi D, Ghaffari A, Gratzl O: Sarcoma of the sella after radiotherapy for pituitary adenoma. Acta Neurochir (Wien); 2010 Oct;152(10):1725-35
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  • [Title] Sarcoma of the sella after radiotherapy for pituitary adenoma.
  • We report the illustrative case of a 38-year-old man with acromegaly who had transsphenoidal surgery and radiotherapy 7 years before presenting with a sellar high-grade sarcoma.
  • We performed a thorough search of the literature and reviewed numerous publications and reports on primary and secondary sarcomas of the sella.
  • For further analysis, we identified and selected a group of patients based on the criteria for studying radiation-induced tumors as described by Cahan.Compared to the surgically treated group, secondary sarcomas of the sella are more frequent in patients who have had radiotherapy.
  • Radiation-induced sarcoma is a rare sequela of pituitary radiotherapy.
  • It is important for the treating physician to keep in mind the possibility of post-radiation sarcoma development.
  • [MeSH-major] Adenoma / radiotherapy. Fibrosarcoma / etiology. Fibrosarcoma / pathology. Pituitary Neoplasms / radiotherapy. Radiotherapy / adverse effects. Skull Base Neoplasms / etiology. Skull Base Neoplasms / pathology
  • [MeSH-minor] Adult. Humans. Male. Spinal Cord Neoplasms / secondary

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  • (PMID = 20512596.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Austria
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92. Pawlicki J, Król R, Kajor M, Ziaja J: [Case of malignant tumour phyllodes converting to fibrosarcoma]. Pol Merkur Lekarski; 2007 Mar;22(129):215-7
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  • [Title] [Case of malignant tumour phyllodes converting to fibrosarcoma].
  • After surgical treatment of recurrent tumours (fibrosarcoma form) occurred two times during 1 year time.
  • [MeSH-major] Breast Neoplasms / pathology. Cell Transformation, Neoplastic / pathology. Fibrosarcoma / pathology. Neoplasm Recurrence, Local / pathology. Phyllodes Tumor / pathology
  • [MeSH-minor] Adult. Female. Follow-Up Studies. Humans. Mastectomy. Reoperation. Treatment Outcome

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  • (PMID = 17682679.001).
  • [ISSN] 1426-9686
  • [Journal-full-title] Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego
  • [ISO-abbreviation] Pol. Merkur. Lekarski
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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93. Tsuchido K, Yamada M, Satou T, Otsuki Y, Shimizu S, Kobayashi H: Cytology of sclerosing epithelioid fibrosarcoma in pleural effusion. Diagn Cytopathol; 2010 Oct;38(10):748-53
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  • [Title] Cytology of sclerosing epithelioid fibrosarcoma in pleural effusion.
  • We report a case of sclerosing epithelioid fibrosarcoma focusing on its cytological features in pleural effusion.
  • The histological diagnosis was sclerosing epithelioid fibrosarcoma with a negative surgical margin.
  • A histological examination revealed a metastasis of sclerosing epithelioid fibrosarcoma, and chemotherapy was initiated.
  • The above cytological features, coupled with the clinical findings, enabled a diagnosis of sclerosing epithelioid fibrosarcoma.
  • To our knowledge, this is the first cytological description of sclerosing epithelioid fibrosarcoma.
  • [MeSH-major] Cytodiagnosis. Fibrosarcoma / secondary. Pleural Effusion, Malignant / pathology
  • [MeSH-minor] Adult. Buttocks / pathology. Epithelioid Cells / pathology. Humans. Immunohistochemistry. Lung Neoplasms / secondary. Male. Sclerosis / pathology. Soft Tissue Neoplasms / secondary

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  • [Copyright] © 2010 Wiley-Liss, Inc.
  • (PMID = 20091700.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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94. MacDonald MJ, Longacre MJ, Langberg EC, Tibell A, Kendrick MA, Fukao T, Ostenson CG: Decreased levels of metabolic enzymes in pancreatic islets of patients with type 2 diabetes. Diabetologia; 2009 Jun;52(6):1087-91
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  • In diabetic islets, the mRNA signal of the islet cell-enriched transcription factor musculoaponeurotic fibrosarcoma oncogene homologue A, which regulates expression of islet genes, including the PC gene, was decreased to 54% of the control level.

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  • [Cites] J Histochem Cytochem. 1975 Sep;23(9):660-5 [240882.001]
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  • (PMID = 19296078.001).
  • [ISSN] 1432-0428
  • [Journal-full-title] Diabetologia
  • [ISO-abbreviation] Diabetologia
  • [Language] ENG
  • [Grant] United States / NIDDK NIH HHS / DK / DK028348-25; United States / NIDDK NIH HHS / DK / R01 DK028348-24; United States / NIDDK NIH HHS / DK / DK28348; United States / NIDDK NIH HHS / DK / DK028348-17; United States / NIDDK NIH HHS / DK / DK028348-18; United States / NIDDK NIH HHS / DK / DK028348-22; United States / NIDDK NIH HHS / DK / R01 DK028348-18; United States / NIDDK NIH HHS / DK / R01 DK028348-25; United States / NIDDK NIH HHS / DK / DK028348-23; United States / NIDDK NIH HHS / DK / R01 DK028348-17; United States / NIDDK NIH HHS / DK / R01 DK028348-20; United States / NIDDK NIH HHS / DK / DK028348-24; United States / NIDDK NIH HHS / DK / DK028348-16; United States / NIDDK NIH HHS / DK / R01 DK028348-16; United States / NIDDK NIH HHS / DK / R01 DK028348-21; United States / NIDDK NIH HHS / DK / R01 DK028348-19; United States / NIDDK NIH HHS / DK / R01 DK028348-27; United States / NIDDK NIH HHS / DK / DK028348-26; United States / NIDDK NIH HHS / DK / R01 DK028348-23; United States / NIDDK NIH HHS / DK / DK028348-20; United States / NIDDK NIH HHS / DK / R01 DK028348-22; United States / NIDDK NIH HHS / DK / R01 DK028348-26; United States / NIDDK NIH HHS / DK / R01 DK028348; United States / NIDDK NIH HHS / DK / DK028348-19; United States / NIDDK NIH HHS / DK / DK028348-21
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] EC 1.1.- / Glycerolphosphate Dehydrogenase; EC 1.1.1.37 / Malate Dehydrogenase; EC 1.1.1.41 / Isocitrate Dehydrogenase; EC 1.1.1.42 / isocitrate dehydrogenase (NADP+); EC 2.3.3.8 / ATP Citrate (pro-S)-Lyase; EC 2.6.1.1 / Aspartate Aminotransferases; EC 2.8.3.- / Coenzyme A-Transferases; EC 2.8.3.5 / 3-ketoacid CoA-transferase; EC 4.1.1.41 / Methylmalonyl-CoA Decarboxylase; EC 6.4.1.1 / Pyruvate Carboxylase
  • [Other-IDs] NLM/ NIHMS203397; NLM/ PMC2903059
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95. Huang HY, Li CF, Fang FM, Tsai JW, Li SH, Lee YT, Wei HM: Prognostic implication of ezrin overexpression in myxofibrosarcomas. Ann Surg Oncol; 2010 Dec;17(12):3212-9
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  • It is implicated in tumor progression and metastatic dissemination, and it is associated with adverse outcomes in several cancer types, including pediatric sarcomas.
  • [MeSH-major] Cytoskeletal Proteins / metabolism. Fibrosarcoma / metabolism. Myxosarcoma / metabolism
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Blotting, Western. Cells, Cultured. Female. Fibroblasts / cytology. Fibroblasts / metabolism. Follow-Up Studies. Humans. Immunoenzyme Techniques. Male. Middle Aged. Neoplasm Staging. Prognosis. RNA, Messenger / genetics. Reverse Transcriptase Polymerase Chain Reaction. Survival Rate. Young Adult

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  • (PMID = 20585869.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cytoskeletal Proteins; 0 / RNA, Messenger; 0 / ezrin
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96. Guo H, Xiong Y, Nong L, Zhang S, Li T: [Reassessment of the pathological diagnosis in 33 cases of malignant fibrous histiocytoma]. Beijing Da Xue Xue Bao; 2008 Aug 18;40(4):374-9
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  • OBJECTIVE: Since malignant fibrous histiocytoma (MFH) may be taken as an undifferentiated pleomorphic sarcoma (UPS), this study was conducted to reassess 33 previously diagnosed MFH cases in the past 10 years based on the latest WHO concept.
  • RESULTS: Among the 33 cases, 17 cases (51.5%) of MFH had their diagnoses changed, including 5 leiomyosarcomas, 3 malignant peripheral nerve sheath tumors, 1 fibrosarcoma, 1 inflammatory myofibrosarcoma, 1 giant cell tumor and 1 angiomatoid fibrous histiocytoma.
  • CONCLUSION: MFH/UPS often show marked histological pleomorphism, and the diagnosis must be made by exclusion of other definitive sarcomas, especially myogenic and neurogenic sarcoma.
  • In addition, histiocytic phenotypic marker did have more expression in MFH/UPS than in other sarcomas.
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Humans. Immunohistochemistry. Middle Aged

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  • (PMID = 18677383.001).
  • [ISSN] 1671-167X
  • [Journal-full-title] Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences
  • [ISO-abbreviation] Beijing Da Xue Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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97. Willems SM, Mohseny AB, Balog C, Sewrajsing R, Briaire-de Bruijn IH, Knijnenburg J, Cleton-Jansen AM, Sciot R, Fletcher CD, Deelder AM, Szuhai K, Hensbergen PJ, Hogendoorn PC: Cellular/intramuscular myxoma and grade I myxofibrosarcoma are characterized by distinct genetic alterations and specific composition of their extracellular matrix. J Cell Mol Med; 2009 Jul;13(7):1291-301
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Extracellular Matrix / metabolism. Fibrosarcoma / genetics. Myxoma / genetics
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Chromatography, Liquid. DNA Mutational Analysis. Extracellular Matrix Proteins / metabolism. Female. GTP-Binding Protein alpha Subunits, Gs / genetics. Gene Expression Regulation, Neoplastic. Humans. Immunohistochemistry. Karyotyping. Male. Mass Spectrometry. Middle Aged. Polymerase Chain Reaction. Proto-Oncogene Proteins / genetics. RNA, Messenger / genetics. RNA, Messenger / metabolism. Tumor Suppressor Protein p53 / genetics. ras Proteins / genetics

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  • (PMID = 19320777.001).
  • [ISSN] 1582-4934
  • [Journal-full-title] Journal of cellular and molecular medicine
  • [ISO-abbreviation] J. Cell. Mol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Extracellular Matrix Proteins; 0 / KRAS protein, human; 0 / Proto-Oncogene Proteins; 0 / RNA, Messenger; 0 / Tumor Suppressor Protein p53; EC 3.6.1.- / GNAS protein, human; EC 3.6.5.1 / GTP-Binding Protein alpha Subunits, Gs; EC 3.6.5.2 / ras Proteins
  • [Other-IDs] NLM/ PMC4496143
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98. Wang M, Khurana RN, Parikh JG, Hidayat AA, Rao NA: Myxofibrosarcoma of the orbit: an underrecognized entity? Case report and review of the literature. Ophthalmology; 2008 Jul;115(7):1237-1240.e2
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  • CONCLUSIONS: For historical reasons, MFS involving the orbit is likely to be underrecognized and categorized erroneously as malignant fibrous histiocytoma or other soft tissue sarcoma.
  • Although orbital MFS is an extremely rare diagnosis, ophthalmologists should be aware of the possibility and consider a diagnosis of MFS when an adult seeks treatment for an orbital tumor with aggressive growth.
  • [MeSH-major] Fibrosarcoma / pathology. Orbital Neoplasms / pathology

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  • (PMID = 18096231.001).
  • [ISSN] 1549-4713
  • [Journal-full-title] Ophthalmology
  • [ISO-abbreviation] Ophthalmology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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99. Perez EA, Gutierrez JC, Moffat FL Jr, Franceschi D, Livingstone AS, Spector SA, Levi JU, Sleeman D, Koniaris LG: Retroperitoneal and truncal sarcomas: prognosis depends upon type not location. Ann Surg Oncol; 2007 Mar;14(3):1114-22
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  • [Title] Retroperitoneal and truncal sarcomas: prognosis depends upon type not location.
  • BACKGROUND: Prognostication of truncal and retroperitoneal soft tissue sarcomas has traditionally been predicated on tumor location and grade.
  • OBJECTIVE: To compare outcomes for patients with retroperitoneal or truncal sarcomas.
  • Liposarcoma and fibrosarcoma were associated with improved survival (P < 0.0001).
  • CONCLUSIONS: Successful operative resection can confer prolonged disease-free survival and cure for truncal and retroperitoneal sarcomas.
  • Future studies should focus on histological subtype rather than tumor location for truncal and retroperitoneal sarcomas.
  • [MeSH-major] Retroperitoneal Neoplasms / pathology. Sarcoma / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Extremities / pathology. Female. Fibrosarcoma / drug therapy. Fibrosarcoma / pathology. Fibrosarcoma / surgery. Histiocytoma, Benign Fibrous / drug therapy. Histiocytoma, Benign Fibrous / pathology. Histiocytoma, Benign Fibrous / surgery. Humans. Leiomyosarcoma / drug therapy. Leiomyosarcoma / pathology. Leiomyosarcoma / surgery. Liposarcoma / drug therapy. Liposarcoma / pathology. Liposarcoma / surgery. Male. Middle Aged. Prognosis. Retrospective Studies. Risk Factors. Survival Rate. Time Factors

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  • (PMID = 17206483.001).
  • [ISSN] 1068-9265
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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100. Kordek R, Sowa P, Panasiuk M, Kmieciak M, Chudobinski C, Pluciennik E, Bednarek AK, Potemski P, Jesionek-Kupnicka D: Primary osseous rhabdomyosarcoma with focal matrix formation mimicking osteosarcoma. Pathol Res Pract; 2007;203(12):873-7
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  • Other bone tumors with rhabdomyosarcomatous differentiation have been described: dedifferentiated chondrosarcoma, fibrosarcoma, and osteosarcoma.
  • [MeSH-minor] Actins / analysis. Adult. Biomarkers, Tumor / analysis. Desmin / analysis. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. MyoD Protein / analysis. Myogenin / analysis

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  • (PMID = 17905523.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Actins; 0 / Biomarkers, Tumor; 0 / Desmin; 0 / MYOG protein, human; 0 / MyoD Protein; 0 / MyoD1 myogenic differentiation protein; 0 / Myogenin
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