[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 75 of about 75
1. Lauridant-Philippin G, Ledem N, Lemoine F, Gouerant S, Guillemet C, Michel P, Scotte M, Di Fiore F: Optimal treatment with systemic chemotherapy, complete surgical excision and hyperthermic intraperitoneal chemotherapy for a desmoplastic small round cell tumor in an adult male patient. Gastroenterol Clin Biol; 2010 Apr-May;34(4-5):321-4
MedlinePlus Health Information. consumer health - Soft Tissue Sarcoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Optimal treatment with systemic chemotherapy, complete surgical excision and hyperthermic intraperitoneal chemotherapy for a desmoplastic small round cell tumor in an adult male patient.
  • Desmoplastic small round cell tumor (DSRCT) is a very rare but aggressive malignancy.
  • The tumor primarily affects the intra-abdominal serosal and is characterized by distinctive histological and immunophenotypic features and by the specific reciprocal translocation EWS-WT1.
  • We report a case of a 51-year old adult patient presenting with a DSRCT treated with aggressive therapy based on systemic chemotherapy, complete cytoreductive surgery associated with hyperthermic intraperitoneal chemotherapy, resulting in a long term survival of 4 years.

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20537477.001).
  • [ISSN] 0399-8320
  • [Journal-full-title] Gastroentérologie clinique et biologique
  • [ISO-abbreviation] Gastroenterol. Clin. Biol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
  •  go-up   go-down


2. Zeeshan-ud-din, Yaqoob N, Pishoroi T, Rafique MZ, Kamran A: Intra-abdominal desmoplastic small round cell tumor. J Pak Med Assoc; 2006 Dec;56(12):608-10
Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intra-abdominal desmoplastic small round cell tumor.
  • Intra-abdominal desmoplastic small round cell tumor (IDSRCT) is a unique, highly aggressive neoplasm that chiefly affects male adolescents and young adults and most frequently presents as a large abdominal mass with widespread peritoneal involvement at the time of diagnosis.
  • [MeSH-major] Carcinoma, Small Cell / diagnosis. Peritoneal Neoplasms / diagnosis
  • [MeSH-minor] Adult. Female. Humans. Immunohistochemistry. Male. Omentum / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17312655.001).
  • [ISSN] 0030-9982
  • [Journal-full-title] JPMA. The Journal of the Pakistan Medical Association
  • [ISO-abbreviation] J Pak Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
  •  go-up   go-down


3. Eiriz Martínez S, Conceição E Silva JP: [Desmoplastic small round cell tumor of the abdomen: CT findings and radiologic-pathologic correlation in 3 cases]. Radiologia; 2009 May-Jun;51(3):313-7
MedlinePlus Health Information. consumer health - CT Scans.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Desmoplastic small round cell tumor of the abdomen: CT findings and radiologic-pathologic correlation in 3 cases].
  • [Transliterated title] Tumor desmoplástico de células pequeñas y redondas abdominal: hallazgos en tomografía computarizada y correlación anatomorradiológica en 3 casos.
  • We describe the CT findings of abdominal desmoplastic small round cell tumor (DSRCT) in three patients.
  • [MeSH-minor] Adolescent. Child. Humans. Male. Young Adult

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19298986.001).
  • [ISSN] 0033-8338
  • [Journal-full-title] Radiología
  • [ISO-abbreviation] Radiologia
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  •  go-up   go-down


Advertisement
4. Santos Gorjón P, Gómez González JL, Batuecas Caletrío A, Flores Corral MT, Sánchez González F: [Small round cell desmoplastic tumour. Atypical morphology in the sub-maxillary gland]. Acta Otorrinolaringol Esp; 2009 Mar-Apr;60(2):141-3
MedlinePlus Health Information. consumer health - Salivary Gland Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Small round cell desmoplastic tumour. Atypical morphology in the sub-maxillary gland].
  • [Transliterated title] Tumor desmoplásico de células pequeñas y redondas. Morfología atípica en la glándula submaxilar.
  • Desmoplastic small round cell tumour (DSRCT) is a rare disease usually affecting young males.
  • The tumour consists of nests and masses of undifferentiated small round cells embedded in a desmoplastic stroma.
  • The co-expression of epithelial, muscular and neuronal antigens distinguishes this entity from other small round cell tumours.
  • We report a case of desmoplastic small round cell tumour of the sub-maxillary gland, with an evolution of 8 months, affecting a 36 year old male.
  • [MeSH-minor] Adult. Humans. Male

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19401082.001).
  • [ISSN] 0001-6519
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  •  go-up   go-down


5. Deng J, Xu N, Shen P, Wang Z, Zhang X, Lou H, Shi G: Bone marrow metastasis of desmoplastic small round cell tumor. Tumori; 2007 Sep-Oct;93(5):511-3
Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bone marrow metastasis of desmoplastic small round cell tumor.
  • Desmoplastic small round cell tumor is an extremely rare and highly aggressive neoplasm.
  • We present a case of clinically symptomatic bone marrow metastasis in a 25-year-old woman with a diagnosis of desmoplastic small round cell tumor originating from the pelvic cavity.
  • [MeSH-major] Bone Marrow Neoplasms / secondary. Carcinoma, Small Cell / secondary. Pelvic Neoplasms / pathology
  • [MeSH-minor] Adult. Female. Humans

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18038889.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


6. Baz W, El-Soueidi R, Nakhl F, Aoun N, Chin N, Dhar M: Desmoplastic small round-cell tumor: an adult with previous exposure to agent orange. Jpn J Clin Oncol; 2010 Jun;40(6):593-5
Hazardous Substances Data Bank. 2,4-D .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic small round-cell tumor: an adult with previous exposure to agent orange.
  • Desmoplastic small round-cell tumor is an uncommon, highly aggressive tumor with a predilection for pediatric age groups and young adults.
  • Although Agent Orange has been associated with soft-tissue sarcoma, an association with desmoplastic small round-cell tumor has not been reported.
  • Omental core needle biopsy was consistent with desmoplastic small round-cell tumor based on morphology and immunohistochemistry.
  • [MeSH-major] 2,4,5-Trichlorophenoxyacetic Acid / adverse effects. 2,4-Dichlorophenoxyacetic Acid / adverse effects. Abdominal Neoplasms / chemically induced. Defoliants, Chemical / adverse effects. Sarcoma, Small Cell / chemically induced. Tetrachlorodibenzodioxin / adverse effects. Veterans. Vietnam Conflict

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • Hazardous Substances Data Bank. 2,4,5-T .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20382635.001).
  • [ISSN] 1465-3621
  • [Journal-full-title] Japanese journal of clinical oncology
  • [ISO-abbreviation] Jpn. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Defoliants, Chemical; 2577AQ9262 / 2,4-Dichlorophenoxyacetic Acid; 39277-47-9 / Agent Orange; 9Q963S4YMX / 2,4,5-Trichlorophenoxyacetic Acid; DO80M48B6O / Tetrachlorodibenzodioxin
  •  go-up   go-down


7. Coulibalya B, Liprandia A, Le Hémon A, Fernandez C, Hardwigsen J, Berthet B, Bouvier C: [Desmoplastic small round-cell tumor: two cases of diffuse abdominopelvic infiltration]. Gastroenterol Clin Biol; 2008 Mar;32(3):278-81
Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Desmoplastic small round-cell tumor: two cases of diffuse abdominopelvic infiltration].
  • Desmoplastic small round-cell tumors are a rare malignant tumor that affects male children and young adults.
  • We report two cases of desmoplastic small round-cell tumors, with diffuse infiltration in the abdomen and pelvis in two adult caucasian males.
  • The first case-report is a middle-aged man and the second a young adult man with early recurrence and diffuse metastatic lymph nodes.
  • [MeSH-minor] Adult. Chemotherapy, Adjuvant. Fatal Outcome. Humans. Lymphatic Metastasis. Male. Neoplasm Invasiveness

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18663785.001).
  • [ISSN] 0399-8320
  • [Journal-full-title] Gastroentérologie clinique et biologique
  • [ISO-abbreviation] Gastroenterol. Clin. Biol.
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  •  go-up   go-down


8. García-González J, Villanueva C, Fernández-Aceñero MJ, Paniagua P: Paratesticular desmoplastic small round cell tumor: case report. Urol Oncol; 2005 Mar-Apr;23(2):132-4
MedlinePlus Health Information. consumer health - Testicular Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Paratesticular desmoplastic small round cell tumor: case report.
  • BACKGROUND: The desmoplastic small round cell tumor has recently been separated from other small round cell tumors because of its characteristic pathological and clinical features.
  • However, in recent years there have reports on desmoplastic small round cell tumors affecting other body regions, including the paratesticular area.
  • Physical examination revealed a round elastic firm 2 to 3 cm mass distal to the tail of the epididymis, which was excised with a preoperative diagnosis of adenomatoid tumor.
  • However, histological and immunohistochemical diagnosis confirmed a desmoplastic small round cell tumor.
  • CONCLUSIONS: Recent reviews on desmoplastic small round cell tumor affecting the paratesticular area have shown a better prognosis for tumors of this origin compared to abdominal ones.
  • [MeSH-major] Carcinoma, Small Cell / pathology. Epididymis / pathology. Testicular Neoplasms / pathology
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Disease-Free Survival. Humans. Male

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15869999.001).
  • [ISSN] 1078-1439
  • [Journal-full-title] Urologic oncology
  • [ISO-abbreviation] Urol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


9. Thijs AM, van der Graaf WT, van Herpen CM: Temsirolimus for metastatic desmoplastic small round cell tumor. Pediatr Blood Cancer; 2010 Dec 15;55(7):1431-2
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Temsirolimus for metastatic desmoplastic small round cell tumor.
  • Desmoplastic small round cell tumor (DSRCT) is a rare and aggressive neoplasm that mostly occurs in young males.
  • No curative treatment options currently exist for this type of tumor and long-term survival remains poor.
  • In vitro rapamycin induces apoptotic death of JN-DSRCT-1 cells, a possible model for desmoplastic small round cell tumors in which the EWS gene is fused to the WT1 gene.
  • [MeSH-minor] Humans. Liver Neoplasms / drug therapy. Liver Neoplasms / secondary. Lung Neoplasms / drug therapy. Lung Neoplasms / secondary. Lymphatic Metastasis. Male. Young Adult

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • MedlinePlus Health Information. consumer health - Cancer Chemotherapy.
  • Hazardous Substances Data Bank. SIROLIMUS .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20730888.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Protein Kinase Inhibitors; 624KN6GM2T / temsirolimus; EC 2.7.1.1 / TOR Serine-Threonine Kinases; W36ZG6FT64 / Sirolimus
  •  go-up   go-down


10. Muramatsu T, Shimamura M, Furuichi M, Nishii T, Takeshita S, Shiono M: Desmoplastic small round cell tumor of the lung. Ann Thorac Surg; 2010 Dec;90(6):e86-7
MedlinePlus Health Information. consumer health - Lung Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic small round cell tumor of the lung.
  • We report a rare case of desmoplastic small round cell tumor, which arose from the left lung.
  • A thoracoscopic tumor biopsy was performed under general anesthesia.
  • According to the histopathologic findings of permanent sections, the tumor was composed of sharply outlined nests, clusters, and trabeculae of small round to oval cells separated by a spindle-shaped desmoplastic stroma.
  • A gene analysis revealed chimera genes of Ewing's sarcoma and Wilms' tumor by reverse transcription polymerase chain reaction.
  • [MeSH-major] Desmoplastic Small Round Cell Tumor / diagnosis. Lung Neoplasms / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Fatal Outcome. Humans. Male. Pneumonectomy / methods. Radiography, Thoracic. Tomography, X-Ray Computed

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
  • (PMID = 21095292.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  •  go-up   go-down


11. Hayes-Jordan A, Anderson P, Curley S, Herzog C, Lally KP, Green HL, Hunt K, Mansfield P: Continuous hyperthermic peritoneal perfusion for desmoplastic small round cell tumor. J Pediatr Surg; 2007 Aug;42(8):E29-32
Hazardous Substances Data Bank. DACARBAZINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Continuous hyperthermic peritoneal perfusion for desmoplastic small round cell tumor.
  • Desmoplastic small round cell tumor (DSRCT) is a rare disease of children, adolescents, and young adults that begins and spreads on the peritoneal surfaces.
  • Desmoplastic small round cell tumor usually presents with diffuse abdominal metastatic disease similar in gross appearance to carcinomatosis.
  • These are the first pediatric case reports of DSRCT being treated with continuous hyperthermic peritoneal perfusion, a procedure usually used in treatment of adult carcinomatosis.

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. CIS-DIAMINEDICHLOROPLATINUM .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17706484.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 7673326042 / irinotecan; 7GR28W0FJI / Dacarbazine; 85622-93-1 / temozolomide; Q20Q21Q62J / Cisplatin; XT3Z54Z28A / Camptothecin
  •  go-up   go-down


12. Bland AE, Shah AA, Piscitelli JT, Bentley RC, Secord AA: Desmoplastic small round cell tumor masquerading as advanced ovarian cancer. Int J Gynecol Cancer; 2008 Jul-Aug;18(4):847-50
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic small round cell tumor masquerading as advanced ovarian cancer.
  • Desmoplastic small round cell tumor (DSRCT) is a rare abdominal malignancy usually diagnosed in young adult males.
  • She had a large intraabdominal tumor on ultrasound, thought to be ovarian cancer.
  • [MeSH-major] Carcinoma, Small Cell / diagnosis. Ovarian Neoplasms / diagnosis. Peritoneal Neoplasms / diagnosis
  • [MeSH-minor] Adult. Chromosomes, Human, Pair 11. Chromosomes, Human, Pair 22. Diagnosis, Differential. Disease Progression. Female. Humans. Omentum / pathology. Translocation, Genetic

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • Genetic Alliance. consumer health - Ovarian cancer.
  • MedlinePlus Health Information. consumer health - Ovarian Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18081791.001).
  • [ISSN] 1525-1438
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


13. Mekni A, Maamouri N, Zidi Y, Braham E, Fareh F, Bellil K, Haouet S, Kchir N, Jilani SB, Zitouna M: Desmoplastic small round cell tumor of the abdomen. Report of two cases. Pathologica; 2007 Apr;99(2):54-6
Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic small round cell tumor of the abdomen. Report of two cases.
  • Desmoplastic small round cell tumor (DSRCT) is a rare clinicopathological entity individualized in 1989.
  • [MeSH-minor] Adolescent. Adult. Female. Humans. Male

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17633809.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 14
  •  go-up   go-down


14. Yang Y, Wang H, Wang YP, Zhang W, Hui YZ, Wang ZH, Zheng J: [Detection of EWS-WT1 fusion transcripts in paraffin-embedded tissues for desmoplastic small round cell tumor]. Beijing Da Xue Xue Bao; 2005 Jun 18;37(3):325-8
Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Detection of EWS-WT1 fusion transcripts in paraffin-embedded tissues for desmoplastic small round cell tumor].
  • OBJECTIVE: To detect the EWS-WT1 chimeric mRNA in desmoplastic small round cell tumor (DSRCT) and its clinicopathological significance.
  • METHODS: Formalin fixed, paraffin-embedded tumor specimens from 4 examples of this entity were studied by reverse transcriptase polymerase chain reaction to detect the EWS-WT1 fusion transcripts resulting from the chromosomal translocation t(11;22)(p13;q12).
  • The following tumor specimens were included as controls: 2 Ewing's sarcomas/primitive neuroectodermal tumors (PNET/ES), 2 alveolar rhabdomyosarcomas, and 2 lymphomas.
  • RESULTS: EWS-WT1 fusion transcripts were detected in 3 of 4 desmoplastic small round cell tumors but not in any other tumor types studied as controls.
  • [MeSH-major] Abdominal Neoplasms / genetics. Biomarkers, Tumor / analysis. Carcinoma, Small Cell / genetics. Oncogene Proteins, Fusion / analysis
  • [MeSH-minor] Adult. Female. Humans. Male. Middle Aged. Paraffin Embedding

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15968330.001).
  • [ISSN] 1671-167X
  • [Journal-full-title] Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences
  • [ISO-abbreviation] Beijing Da Xue Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / EWS1-WT1 fusion protein, human; 0 / Oncogene Proteins, Fusion
  •  go-up   go-down


15. Chang F: Desmoplastic small round cell tumors: cytologic, histologic, and immunohistochemical features. Arch Pathol Lab Med; 2006 May;130(5):728-32

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic small round cell tumors: cytologic, histologic, and immunohistochemical features.
  • Desmoplastic small round cell tumor (DSRCT) is a recently recognized clinicopathologic entity that has a predilection for adolescent males and usually affects the abdominal cavity.
  • Due to its uncommon nature, many pathologists lack experience with this tumor.
  • Morphologic features of DSRCT and its immunohistochemical and cytogenetic profile are summarized and differential diagnosis with other small round cell tumors is discussed.
  • As observed by both histologic and cytologic examinations, small round blue cells and fibrosclerotic stroma are the striking morphologic features of DSRCT.
  • Cytogenetically, this tumor harbors a specific karyotypic abnormality, namely t(11;22)(p13;q12).
  • These features distinguish DSRCT from other members of the family of small round cell tumors.
  • [MeSH-major] Abdominal Neoplasms / pathology. Carcinoma, Small Cell / pathology. Chromosomes, Human, Pair 11. Translocation, Genetic
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Chromosomes, Human, Pair 22. Humans. Karyotyping. Male

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16683894.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 30
  •  go-up   go-down


16. Ota S, Ushijima K, Fujiyoshi N, Fujimoto T, Hayashi R, Murakami F, Komai K, Fujiyoshi K, Hori D, Kamura T: Desmoplastic small round cell tumor in the ovary: Report of two cases and literature review. J Obstet Gynaecol Res; 2010 Apr;36(2):430-4
MedlinePlus Health Information. consumer health - Ovarian Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic small round cell tumor in the ovary: Report of two cases and literature review.
  • Desmoplastic small round cell tumor (DSRCT) is a rare intra-abdominal tumor of uncertain histogenesis that occurs predominantly in young males.
  • We report two cases of DSRCT in young women that presented clinically as ovarian tumor with extensive pelvic and abdominal dissemination.
  • [MeSH-major] Ovarian Neoplasms / pathology. Sarcoma, Small Cell / pathology
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Combined Modality Therapy. Diagnosis, Differential. Fatal Outcome. Female. Humans. Ovary / pathology. Treatment Outcome

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20492402.001).
  • [ISSN] 1447-0756
  • [Journal-full-title] The journal of obstetrics and gynaecology research
  • [ISO-abbreviation] J. Obstet. Gynaecol. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Australia
  •  go-up   go-down


17. Ferrari A, Grosso F, Stacchiotti S, Meazza C, Zaffignani E, Marchianò A, Casanova M: Response to vinorelbine and low-dose cyclophosphamide chemotherapy in two patients with desmoplastic small round cell tumor. Pediatr Blood Cancer; 2007 Nov;49(6):864-6
Hazardous Substances Data Bank. VINBLASTINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Response to vinorelbine and low-dose cyclophosphamide chemotherapy in two patients with desmoplastic small round cell tumor.
  • We report two cases of abdominal desmoplastic small round cell tumor (DSRCT) that showed a clinical response to the vinorelbine/low-dose cyclophosphamide combination that has been claimed to be effective for rhabdomyosarcoma.
  • [MeSH-major] Abdominal Neoplasms / drug therapy. Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Liver Neoplasms / drug therapy. Sarcoma, Small Cell / drug therapy. Vinblastine / analogs & derivatives
  • [MeSH-minor] Adolescent. Adult. Biopsy, Fine-Needle. Cyclophosphamide / administration & dosage. Humans. Male. Neoplasm Metastasis. Neoplasm, Residual. Remission Induction. Rhabdomyosarcoma / drug therapy

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • Hazardous Substances Data Bank. CYCLOPHOSPHAMIDE .
  • Hazardous Substances Data Bank. VINORELBINE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2005 Wiley-Liss, Inc.
  • (PMID = 16302215.001).
  • [ISSN] 1545-5009
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 5V9KLZ54CY / Vinblastine; 8N3DW7272P / Cyclophosphamide; Q6C979R91Y / vinorelbine
  •  go-up   go-down


18. Hayes-Jordan A, Green H, Fitzgerald N, Xiao L, Anderson P: Novel treatment for desmoplastic small round cell tumor: hyperthermic intraperitoneal perfusion. J Pediatr Surg; 2010 May;45(5):1000-6
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Novel treatment for desmoplastic small round cell tumor: hyperthermic intraperitoneal perfusion.
  • BACKGROUND: Less than 200 cases have been reported in the world literature since desmoplastic small round cell tumor (DSRCT) was first described in 1989.
  • We used hyperthermic intraperitoneal chemotherapy (HIPEC) at the time of complete tumor resection as an adjunct to treatment of pediatric and adolescent patients with DSRCT.
  • [MeSH-major] Carcinoma, Small Cell / therapy. Chemotherapy, Cancer, Regional Perfusion / methods. Hypothermia, Induced. Peritoneal Neoplasms / therapy
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Combined Modality Therapy / adverse effects. Female. Humans. Infusions, Parenteral. Male. Multivariate Analysis. Neoplasm Staging. Survival Analysis. Treatment Outcome. Young Adult

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright (c) 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20438942.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Controlled Clinical Trial; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


19. Xing PY, Shi YK, Feng FY, Qin Y, Liu P: [Clinical characteristics and treatment of desmoplastic small round cell tumor]. Zhonghua Zhong Liu Za Zhi; 2010 Feb;32(2):139-42
Hazardous Substances Data Bank. VINCRISTINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clinical characteristics and treatment of desmoplastic small round cell tumor].
  • OBJECTIVE: To investigate the clinical characteristics and treatment of desmoplastic small round cell tumor.
  • In 46 patients (86.8%), the primary tumor was located in the abdomen or pelvis.
  • Complete tumor resection was significantly correlated with long survival.
  • The 1- and 3-year survival rates were 70.5% and 53.7% in patients treated with complete tumor resection compared to 37.2% and 4.8% in the incomplete tumor resection cohort (P = 0.0020).
  • CONCLUSION: Complete tumor resection results in improved survival in patients with DSRCT.
  • [MeSH-major] Abdominal Neoplasms / pathology. Abdominal Neoplasms / therapy. Desmoplastic Small Round Cell Tumor / pathology. Desmoplastic Small Round Cell Tumor / therapy
  • [MeSH-minor] Adolescent. Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bone Neoplasms / secondary. Combined Modality Therapy. Cyclophosphamide / therapeutic use. Doxorubicin / therapeutic use. Etoposide / therapeutic use. Female. Follow-Up Studies. Humans. Ifosfamide / therapeutic use. Liver Neoplasms / secondary. Lymph Node Excision. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Recurrence, Local. Prostatic Neoplasms / pathology. Prostatic Neoplasms / therapy. Radiotherapy, Conformal. Surgical Procedures, Operative. Survival Rate. Vincristine / therapeutic use. Young Adult

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • Hazardous Substances Data Bank. DOXORUBICIN .
  • Hazardous Substances Data Bank. ETOPOSIDE .
  • Hazardous Substances Data Bank. IFOSFAMIDE .
  • Hazardous Substances Data Bank. CYCLOPHOSPHAMIDE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20403246.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] China
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 6PLQ3CP4P3 / Etoposide; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; UM20QQM95Y / Ifosfamide; IVAD protocol
  •  go-up   go-down


20. Lal DR, Su WT, Wolden SL, Loh KC, Modak S, La Quaglia MP: Results of multimodal treatment for desmoplastic small round cell tumors. J Pediatr Surg; 2005 Jan;40(1):251-5
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Results of multimodal treatment for desmoplastic small round cell tumors.
  • PURPOSE: Desmoplastic small round cell tumors (DSRCTs) are rare aggressive neoplasms that frequently present with large symptomatic intraabdominal masses.
  • Data were collected on patient demographics, presenting symptoms, tumor location and extent, treatment regimen, and overall survival.
  • In 63 patients (96%), the primary tumor was located in the abdomen or pelvis.
  • Gross tumor resection was highly significant in prolonging overall survival; 3-year survival was 58% in patients treated with gross tumor resection compared to no survivors past 3 years in the nonresection cohort (P < .00001).
  • [MeSH-major] Sarcoma, Small Cell / therapy. Soft Tissue Neoplasms / therapy
  • [MeSH-minor] Abdominal Neoplasms / pathology. Abdominal Neoplasms / surgery. Abdominal Neoplasms / therapy. Adolescent. Adult. Antineoplastic Agents / therapeutic use. Child. Combined Modality Therapy. Female. Humans. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Metastasis. Pelvic Neoplasms / pathology. Pelvic Neoplasms / surgery. Pelvic Neoplasms / therapy. Radiotherapy. Surgical Procedures, Operative. Survival Analysis. Testicular Neoplasms / pathology. Testicular Neoplasms / surgery. Testicular Neoplasms / therapy. Thoracic Neoplasms / pathology. Thoracic Neoplasms / surgery. Thoracic Neoplasms / therapy. Treatment Outcome

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15868593.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  •  go-up   go-down


21. Biswas G, Laskar S, Banavali SD, Gujral S, Kurkure PA, Muckaden M, Parikh PM, Nair CN: Desmoplastic small round cell tumor: extra abdominal and abdominal presentations and the results of treatment. Indian J Cancer; 2005 Apr-Jun;42(2):78-84
Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic small round cell tumor: extra abdominal and abdominal presentations and the results of treatment.
  • BACKGROUND: Desmoplastic small round cell tumor (DSRCT) is a rare malignant neoplasm of adolescent males.
  • The overall survival was poor except in patients who had complete excision of the tumor.
  • [MeSH-major] Abdominal Neoplasms / therapy. Carcinoma, Small Cell / therapy
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Combined Modality Therapy. Female. Humans. India / epidemiology. Infant. Male. Medical Records. Neoplasm Staging. Retrospective Studies. Survival Analysis. Tomography, X-Ray Computed

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16141506.001).
  • [ISSN] 0019-509X
  • [Journal-full-title] Indian journal of cancer
  • [ISO-abbreviation] Indian J Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Evaluation Studies; Journal Article
  • [Publication-country] India
  •  go-up   go-down


22. Yin WH, Guo SP, Yang HY, Chan JK: Desmoplastic small round cell tumor of the submandibular gland--a rare but distinctive primary salivary gland neoplasm. Hum Pathol; 2010 Mar;41(3):438-42
Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic small round cell tumor of the submandibular gland--a rare but distinctive primary salivary gland neoplasm.
  • Desmoplastic small round cell tumor is a highly aggressive neoplasm that generally involves the peritoneum and pelvis of young patients.
  • We report a case presenting as a primary submandibular gland tumor in a 24-year-old man.
  • Histologically, although there were irregular tumor islands lying in an abundant desmoplastic stroma, there were also areas comprising large cellular islands with scanty stroma in between, raising the differential diagnosis of various salivary gland carcinomas.
  • The tumor cells were medium sized, with hyperchromatic nuclei and moderate amounts of cytoplasm.
  • The diagnosis of desmoplastic small round cell tumor was confirmed by the presence of a polyphenotypic immunoprofile (positive for cytokeratin, desmin, and neuron-specific enolase) and the characteristic EWS-WT1 gene fusion.
  • Although rare, desmoplastic small round cell tumor has to be considered in the differential diagnosis of poorly differentiated neoplasms of the salivary gland, especially in young patients.
  • [MeSH-major] Sarcoma, Small Cell / pathology. Submandibular Gland Neoplasms / pathology
  • [MeSH-minor] Cell Proliferation. Combined Modality Therapy. Desmin / metabolism. Disease-Free Survival. Humans. Immunohistochemistry. In Situ Hybridization, Fluorescence. Keratins / metabolism. Male. RNA, Messenger / metabolism. Reverse Transcriptase Polymerase Chain Reaction. Treatment Outcome. Tumor Suppressor Protein p53 / metabolism. Young Adult

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • [CommentIn] Hum Pathol. 2010 Apr;41(4):616-7; author reply 617 [20226963.001]
  • (PMID = 19913282.001).
  • [ISSN] 1532-8392
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Desmin; 0 / RNA, Messenger; 0 / Tumor Suppressor Protein p53; 68238-35-7 / Keratins
  •  go-up   go-down


23. Sha JJ, Lu JW, Zhu JS, Huang XY, Wang YX: [Desmoplastic small round-cell tumor of the paratesticular region: a case report and review of the literature]. Zhonghua Nan Ke Xue; 2007 Oct;13(10):918-20
MedlinePlus Health Information. consumer health - Testicular Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Desmoplastic small round-cell tumor of the paratesticular region: a case report and review of the literature].
  • OBJECTIVE: To investigate the clinical and pathological features of paratesticular desmoplastic small round cell tumor (DSRCT), and to improve the diagnosis and treatment of the disease.
  • RESULTS: During the operation the paratesticular area was found full of multiple nodular tumor masses of various sizes ranging from 0.5 cm to 1.5 cm in diameter.
  • Pathological examination showed the characteristic histological pattern of nests of small undifferentiated cells embedded in a dense fibrous stroma.
  • The tumor presented an immunohistochemical feature of epithelial, mesenchymal as well as neural multidirectional differentiation.
  • Following testicular tumor orchiectomy, chemotherapy was performed with DDP, VP16, ifosfamide and EPI.
  • Three years follow-up found no tumor recurrence.
  • CONCLUSION: Desmoplastic small round cell tumor has a specific clinicopathologic stigmata, usually occurring in young males, for which surgical resection with chemotherapy is the treatment of choice.
  • [MeSH-major] Carcinoma, Small Cell / diagnosis. Fibroma, Desmoplastic / diagnosis. Testicular Neoplasms / diagnosis
  • [MeSH-minor] Adult. Combined Modality Therapy. Humans. Male. Treatment Outcome

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17977326.001).
  • [ISSN] 1009-3591
  • [Journal-full-title] Zhonghua nan ke xue = National journal of andrology
  • [ISO-abbreviation] Zhonghua Nan Ke Xue
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] China
  • [Number-of-references] 13
  •  go-up   go-down


24. Rais H, Elmansouri F, Belaabidia B, Essadki O, Oussehal A, Sarf I: [Paratesticular desmoplastic small round cell tumour: case report with literature review]. Cancer Radiother; 2010 Apr;14(2):111-4
MedlinePlus Health Information. consumer health - Testicular Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Paratesticular desmoplastic small round cell tumour: case report with literature review].
  • Desmoplastic small round cell tumors are rare aggressive cancers of adolescence and early adulthood.
  • It has recently been separated from other small round cell tumors because of its pathological characteristics and clinical features.
  • However, in recent years there have been reports on desmoplastic small round cell tumors affecting other body regions, including the paratesticular area.
  • Physical examination revealed a round elastic firm 1-cm mass of the epididymis, which was excised.
  • Histological and immunohistochemical diagnosis confirmed a desmoplastic small round cell tumor.
  • Recent reviews on desmoplastic small round cell tumors affecting the paratesticular area have shown a better prognosis for tumors of this origin compared to abdominal ones.
  • [MeSH-minor] Adolescent. Adult. Cell Division. Child. Humans. Immunohistochemistry. Keratins / genetics. Male. Orchiectomy. Reverse Transcriptase Polymerase Chain Reaction. Tomography, X-Ray Computed. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright (c) 2009. Published by Elsevier SAS.
  • (PMID = 20189431.001).
  • [ISSN] 1769-6658
  • [Journal-full-title] Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
  • [ISO-abbreviation] Cancer Radiother
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 68238-35-7 / Keratins
  •  go-up   go-down


25. Lee YS, Hsiao CH: Desmoplastic small round cell tumor: a clinicopathologic, immunohistochemical and molecular study of four patients. J Formos Med Assoc; 2007 Oct;106(10):854-60
Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic small round cell tumor: a clinicopathologic, immunohistochemical and molecular study of four patients.
  • BACKGROUND/PURPOSE: Desmoplastic small round cell tumor (DSRCT) is a rare but highly aggressive tumor that usually occurs in the abdominal cavity of young males.
  • Immunohistochemical staining plays an important role in the differentiation of DSRCT from other small round cell neoplasms.
  • Histologically, the tumors were composed of nests of primitive small round cells within a desmoplastic stroma.
  • Immunohistochemically, all the tumor cells were reactive to cytokeratin, vimentin, desmin and WT-1.
  • CONCLUSION: DSRCT is an aggressive tumor that usually occurs in the peritoneum of young males.
  • The tumor is characterized by the expression of cytokeratin, vimentin, desmin and WT-1.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17964965.001).
  • [ISSN] 0929-6646
  • [Journal-full-title] Journal of the Formosan Medical Association = Taiwan yi zhi
  • [ISO-abbreviation] J. Formos. Med. Assoc.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] Singapore
  • [Chemical-registry-number] 0 / Antibodies; 0 / EWS1-WT1 fusion protein, human; 0 / Oncogene Proteins, Fusion
  •  go-up   go-down


26. Doros L, Kaste SC, Rodriguez-Galindo C: Sister Mary Joseph's nodule as presenting sign of a desmoplastic small round cell tumor. Pediatr Blood Cancer; 2008 Feb;50(2):388-90
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sister Mary Joseph's nodule as presenting sign of a desmoplastic small round cell tumor.
  • Umbilical metastases, also named Sister Mary Joseph's nodules, are well documented in the adult population and most often represent an underlying intra-abdominal malignancy, usually a carcinoma of gastrointestinal or gynecologic origin.
  • A 14-year-old male presented with an umbilical mass, which was found to be a metastatic lesion of a desmoplastic small round cell tumor (DSRCT) of the abdomen.
  • [MeSH-major] Abdominal Neoplasms / secondary. Carcinoma, Small Cell / secondary. Umbilicus / pathology

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2007 Wiley-Liss, Inc.
  • (PMID = 16732579.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA-21765; United States / NCI NIH HHS / CA / CA-71907
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


27. Neder L, Scheithauer BW, Turel KE, Arnesen MA, Ketterling RP, Jin L, Moynihan TJ, Giannini C, Meyer FB: Desmoplastic small round cell tumor of the central nervous system: report of two cases and review of the literature. Virchows Arch; 2009 Apr;454(4):431-9
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic small round cell tumor of the central nervous system: report of two cases and review of the literature.
  • Desmoplastic small round cell tumor (DSRCT) is a malignant tumor often involving the abdominal and/or pelvic peritoneum.
  • Although rare, DSRCT warrants consideration in the differential diagnosis of "malignant small blue cell tumors" of the CNS.
  • [MeSH-major] Carcinoma, Small Cell / pathology. Cerebellar Neoplasms / pathology. Cerebellopontine Angle / pathology
  • [MeSH-minor] Adult. Humans. Immunohistochemistry. In Situ Hybridization, Fluorescence. Magnetic Resonance Imaging. Male. Oncogene Proteins, Fusion / genetics. Reverse Transcriptase Polymerase Chain Reaction

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Am J Surg Pathol. 1992 Oct;16(10):998-1006 [1384373.001]
  • [Cites] J Neuropathol Exp Neurol. 2002 Mar;61(3):215-25; discussion 226-9 [11895036.001]
  • [Cites] Am J Surg Pathol. 1998 Nov;22(11):1303-13 [9808123.001]
  • [Cites] Am J Surg Pathol. 1990 Jul;14(7):633-42 [2356923.001]
  • [Cites] J Clin Oncol. 1998 Sep;16(9):3028-36 [9738572.001]
  • [Cites] Diagn Mol Pathol. 1998 Feb;7(1):24-8 [9646031.001]
  • [Cites] Am J Surg Pathol. 1996 Jan;20(1):112-7 [8540602.001]
  • [Cites] Hum Pathol. 1997 Apr;28(4):502-9 [9104953.001]
  • [Cites] Cancer Cell. 2002 Dec;2(6):497-505 [12498718.001]
  • [Cites] Arch Pathol Lab Med. 2006 May;130(5):728-32 [16683894.001]
  • [Cites] Hum Pathol. 1992 Apr;23(4):454-64 [1563748.001]
  • [Cites] Arch Pathol Lab Med. 1989 Sep;113(9):1019-29 [2505732.001]
  • [Cites] Am J Surg Pathol. 2002 Jul;26(7):823-35 [12131150.001]
  • [Cites] Am J Surg Pathol. 1989 May;13(5):413-21 [2469334.001]
  • [Cites] Nature. 1990 Jul 12;346(6280):194-7 [2164159.001]
  • [Cites] Am J Surg Pathol. 1995 Jun;19(6):659-65 [7755152.001]
  • [Cites] Diagn Mol Pathol. 2005 Mar;14(1):23-8 [15714060.001]
  • [Cites] Am J Surg Pathol. 1999 Nov;23(11):1408-13 [10555010.001]
  • [Cites] Cancer Genet Cytogenet. 1993 Aug;69(1):17-21 [8374894.001]
  • [Cites] Exp Cell Res. 2001 Mar 10;264(1):74-99 [11237525.001]
  • [Cites] Acta Cytol. 1995 Mar-Apr;39(2):377-8 [7887076.001]
  • [Cites] J Surg Oncol. 1999 Aug;71(4):269-72 [10440769.001]
  • [Cites] J Neurosurg. 1996 Jul;85(1):56-65 [8683283.001]
  • [Cites] Acta Neuropathol. 2007 Aug;114(2):97-109 [17618441.001]
  • [Cites] Acta Cytol. 1993 Jan-Feb;37(1):77-82 [7679537.001]
  • [Cites] Semin Diagn Pathol. 1996 Aug;13(3):204-12 [8875710.001]
  • [Cites] Proc Natl Acad Sci U S A. 1995 Feb 14;92(4):1028-32 [7862627.001]
  • [Cites] Am J Surg Pathol. 2004 May;28(5):644-50 [15105654.001]
  • [Cites] Virchows Arch. 1998 Feb;432(2):135-41 [9504858.001]
  • [Cites] Mod Pathol. 1999 Jul;12(7):729-34 [10430278.001]
  • [Cites] Ultrastruct Pathol. 2000 Sep-Oct;24(5):333-7 [11071572.001]
  • [Cites] Hum Pathol. 1999 Apr;30(4):430-5 [10208465.001]
  • [Cites] Pediatr Pathol. 1989;9(2):177-83 [2473463.001]
  • [Cites] Virchows Arch A Pathol Anat Histopathol. 1991;418(3):207-14 [1900966.001]
  • [Cites] Cancer Res. 1994 Jun 1;54(11):2837-40 [8187063.001]
  • [Cites] Am J Surg Pathol. 1991 Jun;15(6):499-513 [1709557.001]
  • [Cites] Gynecol Oncol. 2000 Oct;79(1):124-8 [11006044.001]
  • [Cites] Arch Pathol Lab Med. 2002 Oct;126(10):1226-8 [12296765.001]
  • [Cites] Semin Cancer Biol. 2005 Jun;15(3):197-205 [15826834.001]
  • [Cites] Semin Diagn Pathol. 2003 Feb;20(1):25-45 [12693673.001]
  • [Cites] Pediatr Blood Cancer. 2008 Oct;51(4):545-8 [18561179.001]
  • (PMID = 19263077.001).
  • [ISSN] 1432-2307
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / EWS1-WT1 fusion protein, human; 0 / Oncogene Proteins, Fusion
  •  go-up   go-down


28. Yang JL, Xu WP, Wang J, Zhu XZ, Zhang RY: [Desmoplastic small round cell tumor: a clinicopathologic study of 15 cases]. Zhonghua Bing Li Xue Za Zhi; 2005 Oct;34(10):650-5
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Desmoplastic small round cell tumor: a clinicopathologic study of 15 cases].
  • OBJECTIVE: To study the clinicopathologic features and immunophenotype of desmoplastic small round cell tumor (DSRCT), and to assess the feasibility of reverse transcriptase-polymerase chain reaction (RT-PCR) as a diagnostic adjunct for DSRCT in routine practice.
  • Ultrasound and computerized tomographic examination revealed single or multiple nodular tumor mass(es) in the peritoneal cavity, measuring 3 cm to 25 cm in greatest diameter (mean tumor diameter = 8.6 cm).
  • Cytologic examination in 1 case showed clusters of small round cells in a hemorrhagic background.
  • The tumor nuclei were hyperchromatic and contained inconspicuous nucleoli.
  • Histologically, the tumor was composed of small, round, ovoid to spindled cells arranged in nests of various shapes and sizes, embedded in a desmoplastic and focally hyalinized stroma.
  • CONCLUSIONS: DSRCT is a highly malignant small round cell tumor occurring predominantly in the abdominal or pelvic cavity of young to middle-aged males.
  • [MeSH-major] Abdominal Neoplasms / pathology. Carcinoma, Small Cell / pathology. Pelvic Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Base Sequence. Child. DNA, Neoplasm / genetics. Female. Humans. Immunophenotyping. Male. Molecular Sequence Data. Oncogene Proteins, Fusion / genetics. Oncogene Proteins, Fusion / metabolism. RNA, Messenger / genetics. RNA, Messenger / metabolism. Retrospective Studies. Tomography, X-Ray Computed

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16536278.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / DNA, Neoplasm; 0 / EWS1-WT1 fusion protein, human; 0 / Oncogene Proteins, Fusion; 0 / RNA, Messenger
  •  go-up   go-down


29. Fang X, Rodabaugh K, Penetrante R, Wong M, Wagner T, Sait S, Mhawech-Fauceglia P: Desmoplastic small round cell tumor (DSRCT) with ovarian involvement in 2 young women. Appl Immunohistochem Mol Morphol; 2008 Jan;16(1):94-9
MedlinePlus Health Information. consumer health - Ovarian Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic small round cell tumor (DSRCT) with ovarian involvement in 2 young women.
  • We report 2 cases of desmoplastic small round cell tumor (DSRCT) involving the ovaries in young women.
  • In both patients, the tumor was widely metastatic at presentation.
  • The ovarian involvement was unilateral in the first patient and bilateral in the second with tumor size ranging from 9 to 11 cm.
  • Despite tumor debulking and multiple chemotherapy regimens, the first patient died at 20 months after initial diagnosis and the second is still undergoing chemotherapy at 7 months after initial presentation.

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18091312.001).
  • [ISSN] 1541-2016
  • [Journal-full-title] Applied immunohistochemistry & molecular morphology : AIMM
  • [ISO-abbreviation] Appl. Immunohistochem. Mol. Morphol.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CA-125 Antigen
  •  go-up   go-down


30. Saab R, Khoury JD, Krasin M, Davidoff AM, Navid F: Desmoplastic small round cell tumor in childhood: the St. Jude Children's Research Hospital experience. Pediatr Blood Cancer; 2007 Sep;49(3):274-9
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic small round cell tumor in childhood: the St. Jude Children's Research Hospital experience.
  • BACKGROUND: Desmoplastic small round cell tumor (DSRCT) is a rare, primarily intra-abdominal tumor that has a poor outcome with current therapies.
  • PROCEDURE: We retrospectively reviewed patient characteristics, presenting symptoms, tumor pathology, treatment, and outcome of 11 pediatric patients with DSRCT at our institution.
  • In eight (73%) patients, the primary tumor was abdominal or pelvic, and in one patient each, it was submental, mediastinal, and paratesticular.
  • One tumor showed rhabdomyoblastic differentiation after therapy.
  • All patients received chemotherapy; eight underwent surgical resection, seven received primary site radiation, and four received myeloablative chemotherapy with stem-cell support.
  • [MeSH-minor] Adolescent. Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Child. Child, Preschool. Combined Modality Therapy. Female. Humans. Male. Oncogene Proteins, Fusion. Retrospective Studies. Survival Analysis

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright (c) 2006 Wiley-Liss, Inc.
  • (PMID = 16685737.001).
  • [ISSN] 1545-5009
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA 21765
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / EWS1-WT1 fusion protein, human; 0 / Oncogene Proteins, Fusion
  •  go-up   go-down


31. Murphy AJ, Bishop K, Pereira C, Chilton-MacNeill S, Ho M, Zielenska M, Thorner PS: A new molecular variant of desmoplastic small round cell tumor: significance of WT1 immunostaining in this entity. Hum Pathol; 2008 Dec;39(12):1763-70
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A new molecular variant of desmoplastic small round cell tumor: significance of WT1 immunostaining in this entity.
  • Desmoplastic small round cell tumor is a rare aggressive neoplasm, often presenting in young adult males.
  • WT1 immunohistochemistry is reportedly useful in distinguishing desmoplastic small round cell tumor from other tumors.
  • Herein, we describe a desmoplastic small round cell tumor of soft tissue with an unusual pattern of WT1 expression associated with a novel variant EWS-WT1 fusion transcript.
  • We compare WT1 expression pattern with 5 intra-abdominal desmoplastic small round cell tumors and review the literature on WT1 expression and variant transcripts in desmoplastic small round cell tumor.
  • Immunohistochemistry for the N- and C-terminals of WT1 was performed in 6 desmoplastic small round cell tumors.
  • The soft tissue desmoplastic small round cell tumor was negative for the WT1 C-terminal and showed nuclear staining with the N-terminal antibody.
  • This tumor also strongly expressed full-length WT1.
  • Five intra-abdominal desmoplastic small round cell tumors showed nuclear staining for WT1 C-terminal, but not for the N-terminal antibody.
  • Although WT1 immunohistochemistry reflects the EWS-WT1 fusion transcript in most desmoplastic small round cell tumors, some cases express full-length WT1 or have variant transcripts, resulting in atypical staining patterns.
  • Hence, interpretation of WT1 immunostaining requires knowledge of antibody target epitopes and correlation with clinical, morphological, and molecular genetic findings for establishing a diagnosis of desmoplastic small round cell tumor.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Sarcoma, Small Cell / metabolism. Soft Tissue Neoplasms / metabolism. WT1 Proteins / metabolism
  • [MeSH-minor] Adolescent. Cell Nucleus / metabolism. Cell Nucleus / pathology. Child. DNA, Neoplasm / analysis. Female. Gene Deletion. Humans. Immunoenzyme Techniques. Male. Oncogene Proteins, Fusion / genetics. Oncogene Proteins, Fusion / metabolism. RNA, Neoplasm / analysis. Reverse Transcriptase Polymerase Chain Reaction. Sequence Analysis, DNA

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18703217.001).
  • [ISSN] 1532-8392
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Neoplasm; 0 / EWS1-WT1 fusion protein, human; 0 / Oncogene Proteins, Fusion; 0 / RNA, Neoplasm; 0 / WT1 Proteins
  •  go-up   go-down


32. Jahraus CD, Glisson SD, St Clair WH: Treatment of desmoplastic small round cell tumor with image-guided intensity modulated radiation therapy as a component of multimodality treatment. Tumori; 2005 May-Jun;91(3):253-5
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Treatment of desmoplastic small round cell tumor with image-guided intensity modulated radiation therapy as a component of multimodality treatment.
  • AIMS AND BACKGROUND: The authors report the case of a 31-year-old black male diagnosed with a pelvic desmoplastic small round-cell tumor who was treated with a unique radiotherapy approach incorporating intensity-modulated radiotherapy and daily ultrasound localization to ensure accurate tumor targeting.
  • Desmoplastic small round-cell tumor is a very rare tumor, most commonly presenting in the abdominopelvic regions of adolescents and young adults.
  • Chemotherapy resulted in tumor shrinkage and was followed by a second-look laparotomy.
  • Additional omental nodules were resected, but the primary tumor was adherent to the rectum and seminal vesicles.
  • CONCLUSIONS: Image-guided intensity-modulated radiotherapy is a feasible option in the treatment of pelvic desmoplastic small round-cell tumor.
  • Pending such confirmation, we continue to be of the impression that desmoplastic small round-cell tumor has an overall unfavorable prognosis, regardless of treatment modalities employed.
  • [MeSH-major] Abdominal Neoplasms / radiotherapy. Carcinoma, Small Cell / radiotherapy
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Combined Modality Therapy. Dose Fractionation. Humans. Male. Radiotherapy / methods

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16206650.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


33. Pinto Marín A, Garrido Arévalo M, Redondo Sánchez A, Espinosa Arranz E, Zamora Auñón P, González Barón M: Intra-abdominal desmoplastic small round cell tumour in a 39-year-old man. Clin Transl Oncol; 2009 Nov;11(11):770-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intra-abdominal desmoplastic small round cell tumour in a 39-year-old man.
  • Desmoplastic small round cell tumor is a very rare neoplasm, that usually appears in children and young adolescents.
  • We report the case of a 39 year-old man and briefly summarize the evidence about this tumor.
  • [MeSH-major] Sarcoma, Ewing / diagnosis. Sarcoma, Small Cell / diagnosis
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Disease Progression. Fatal Outcome. Humans. Lymph Nodes / pathology. Male. Neoplasm Metastasis. Peritoneal Neoplasms / diagnosis. Peritoneal Neoplasms / drug therapy. Peritoneal Neoplasms / pathology. Peritoneum. Prognosis. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Radiology. 1999 Mar;210(3):633-8 [10207460.001]
  • [Cites] Am J Surg Pathol. 1998 Nov;22(11):1303-13 [9808123.001]
  • [Cites] Indian J Cancer. 2005 Apr-Jun;42(2):78-84 [16141506.001]
  • [Cites] Eur J Radiol. 2005 Jun;54(3):438-42 [15899348.001]
  • [Cites] Surg Oncol. 2008 Aug;17(2):107-12 [18191563.001]
  • [Cites] Clin Nucl Med. 1999 Sep;24(9):693-4 [10478748.001]
  • [Cites] Am J Surg Pathol. 1989 May;13(5):413-21 [2469334.001]
  • [Cites] J Pediatr Surg. 2005 Jan;40(1):251-5 [15868593.001]
  • [Cites] Proc Natl Acad Sci U S A. 1995 Feb 14;92(4):1028-32 [7862627.001]
  • [Cites] J Clin Oncol. 2002 Apr 15;20(8):2181-8 [11956280.001]
  • [Cites] Pediatr Pathol. 1989;9(2):177-83 [2473463.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2002 Sep 1;54(1):170-6 [12182988.001]
  • [Cites] Arch Pathol Lab Med. 2007 Apr;131(4):646-9 [17425400.001]
  • [Cites] Eur J Pediatr Surg. 2006 Dec;16(6):423-7 [17211792.001]
  • [Cites] Oncology. 2004;67(3-4):231-42 [15557784.001]
  • [Cites] J Comput Assist Tomogr. 2002 Jul-Aug;26(4):579-83 [12218823.001]
  • (PMID = 19917543.001).
  • [ISSN] 1699-3055
  • [Journal-full-title] Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
  • [ISO-abbreviation] Clin Transl Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


34. Bellah R, Suzuki-Bordalo L, Brecher E, Ginsberg JP, Maris J, Pawel BR: Desmoplastic small round cell tumor in the abdomen and pelvis: report of CT findings in 11 affected children and young adults. AJR Am J Roentgenol; 2005 Jun;184(6):1910-4
MedlinePlus Health Information. consumer health - CT Scans.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic small round cell tumor in the abdomen and pelvis: report of CT findings in 11 affected children and young adults.
  • OBJECTIVE: Our objective was to evaluate the CT features of desmoplastic small round cell tumor (DSRCT) of the abdomen and pelvis in pediatric and young adult patients.
  • [MeSH-major] Abdominal Neoplasms / radiography. Carcinoma, Small Cell / radiography. Pelvic Neoplasms / radiography. Tomography, X-Ray Computed

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15908552.001).
  • [ISSN] 0361-803X
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


35. Chouli M, Viala J, Dromain C, Fizazi K, Duvillard P, Vanel D: Intra-abdominal desmoplastic small round cell tumors: CT findings and clinicopathological correlations in 13 cases. Eur J Radiol; 2005 Jun;54(3):438-42
MedlinePlus Health Information. consumer health - CT Scans.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intra-abdominal desmoplastic small round cell tumors: CT findings and clinicopathological correlations in 13 cases.
  • PURPOSE: We report computed tomography (CT) findings in 13 patients with a primary abdominal desmoplastic small round cell tumor.
  • The main sites of peritoneal involvement were the pelvic space (n=7), omentum (n=5), retroperitoneal space (n=4), small bowel mesentery (n=3), paracolic gutter (n=2 on the right and n=1 on the left), transverse colon mesentery (n=1), peri-splenic space (n=1), peri-hepatic space (n=1).
  • CONCLUSION: Although CT features are nonspecific, the diagnosis of desmoplastic small round cell tumor may be suspected in young men with multiple bulky heterogeneous peritoneal soft tissue masses.
  • [MeSH-minor] Adolescent. Adult. Child. Diagnosis, Differential. Female. Humans. Male. Radiography, Abdominal. Retrospective Studies

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15899348.001).
  • [ISSN] 0720-048X
  • [Journal-full-title] European journal of radiology
  • [ISO-abbreviation] Eur J Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
  •  go-up   go-down


36. Engohan-Aloghe C, Aubain Sommerhausen Nde S, Noël JC: Ovarian involvement by desmoplastic small round cell tumor with leydig cell hyperplasia showing an unusual immunophenotype (cytokeratin negative, calretinin and inhibin positive) mimicking poorly differentiated sertoli leydig cell tumor. Int J Gynecol Pathol; 2009 Nov;28(6):579-83
MedlinePlus Health Information. consumer health - Ovarian Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ovarian involvement by desmoplastic small round cell tumor with leydig cell hyperplasia showing an unusual immunophenotype (cytokeratin negative, calretinin and inhibin positive) mimicking poorly differentiated sertoli leydig cell tumor.
  • Desmoplastic small round cell tumor (DSRCT) is a rare aggressive tumor primarily involving serosal surfaces in adolescents and young men.
  • We report here a variant of DSRCT involving the ovaries that mimics the Sertoli-Leydig cell tumor in a 21-year-old woman complaining of abdominal pain.
  • Frozen section examination identified the right ovarian mass as a poorly differentiated Sertoli-Leydig cell tumor.
  • The surgically resected tumor and left ovary and omentum implants found during laparoscopy were diagnosed as DSRCT with Leydig cell hyperplasia.
  • Immunohistochemically, the tumor cells were negative for epithelial markers but were positive for calretinin and inhibin.
  • [MeSH-major] Carcinoma, Small Cell / pathology. Leydig Cells / pathology. Ovarian Neoplasms / pathology. Sertoli-Leydig Cell Tumor / pathology
  • [MeSH-minor] Adult. Antineoplastic Agents. Calbindin 2. Diagnosis, Differential. Female. Humans. Hyperplasia. Immunohistochemistry. Immunophenotyping. Inhibins / biosynthesis. Male. Peritoneal Neoplasms / drug therapy. Peritoneal Neoplasms / metabolism. Peritoneal Neoplasms / secondary. S100 Calcium Binding Protein G / biosynthesis

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19851210.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / CALB2 protein, human; 0 / Calbindin 2; 0 / S100 Calcium Binding Protein G; 57285-09-3 / Inhibins
  •  go-up   go-down


37. Dave B, Shet T, Chinoy R: Desmoplastic round cell tumor of childhood: can cytology with immunocytochemistry serve as an alternative for tissue diagnosis? Diagn Cytopathol; 2005 Jun;32(6):330-5
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic round cell tumor of childhood: can cytology with immunocytochemistry serve as an alternative for tissue diagnosis?
  • There are limited reports on the cytology of desmoplastic small round cell tumors (DSRCT).
  • The basic cytological impression was that of a cohesive small round cell tumor.
  • [MeSH-major] Abdominal Neoplasms / pathology. Biomarkers, Tumor
  • [MeSH-minor] Adolescent. Adult. Biopsy, Fine-Needle. Humans. Male

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15880716.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down


38. Hassan I, Shyyan R, Donohue JH, Edmonson JH, Gunderson LL, Moir CR, Arndt CA, Nascimento AG, Que FG: Intraabdominal desmoplastic small round cell tumors: a diagnostic and therapeutic challenge. Cancer; 2005 Sep 15;104(6):1264-70
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intraabdominal desmoplastic small round cell tumors: a diagnostic and therapeutic challenge.
  • BACKGROUND: Intraabdominal desmoplastic small round cell tumors (IDSRCT) are uncommon but aggressive tumors that occur in young males.
  • One patient remained alive 72 months after he underwent complete resection of primary and recurrent tumors, and 1 patient remained alive with disease 32 months after he underwent complete resection of a primary tumor.
  • [MeSH-major] Abdominal Neoplasms / therapy. Carcinoma, Small Cell / therapy
  • [MeSH-minor] Adolescent. Adult. Biopsy. Combined Modality Therapy. Humans. Male. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2005 American Cancer Society.
  • (PMID = 16080179.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


39. Liping Cao, Jun Ni, Risheng Que, Zhengrong Wu, Zhenya Song: Desmoplastic small round cell tumor: a clinical, pathological, and immunohistochemical study of 18 Chinese cases. Int J Surg Pathol; 2008 Jul;16(3):257-62
Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic small round cell tumor: a clinical, pathological, and immunohistochemical study of 18 Chinese cases.
  • Desmoplastic small round cell tumor (DSRCT) was first reported in 1989.
  • The survival rate of DSRCT patients is disappointing; however, the survival of patients who had resection of the tumor or received comprehensive clinical treatment is satisfactory.
  • [MeSH-major] Abdominal Neoplasms / pathology. Asian Continental Ancestry Group. Sarcoma, Small Cell / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Biomarkers, Tumor / metabolism. Child. China. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Prognosis. Survival Rate. WT1 Proteins / analysis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18573782.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / WT1 Proteins
  •  go-up   go-down


40. Chang CC, Hsu JT, Tseng JH, Hwang TL, Chen HM, Jan YY: Combined resection and multi-agent adjuvant chemotherapy for desmoplastic small round cell tumor arising in the abdominal cavity: report of a case. World J Gastroenterol; 2006 Feb 7;12(5):800-3
Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Combined resection and multi-agent adjuvant chemotherapy for desmoplastic small round cell tumor arising in the abdominal cavity: report of a case.
  • Desmoplastic small round cell tumor (DSRCT) is a rare, highly aggressive malignancy with distinctive histological features: a nesting pattern of cellular growth within dense desmoplastic stroma, occurring in young population with male predominance.
  • The tumor has co-expressed epithelial, muscle, and neural markers in immunohistochemical studies.
  • [MeSH-major] Abdominal Neoplasms / drug therapy. Abdominal Neoplasms / surgery. Carcinoma, Small Cell / drug therapy. Carcinoma, Small Cell / surgery
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Chemotherapy, Adjuvant. Humans. Male

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Gastroenterol. 2000;35(9):712-6 [11023044.001]
  • [Cites] J Pediatr Hematol Oncol. 1997 Mar-Apr;19(2):172-5 [9149753.001]
  • [Cites] Oncology. 2003;64(1):14-7 [12457026.001]
  • [Cites] Pediatr Pathol. 1989;9(2):177-83 [2473463.001]
  • [Cites] Am J Surg Pathol. 1991 Jun;15(6):499-513 [1709557.001]
  • [Cites] Acta Cytol. 1993 Jan-Feb;37(1):77-82 [7679537.001]
  • [Cites] Oncology. 2004;67(3-4):231-42 [15557784.001]
  • [Cites] Genes Chromosomes Cancer. 1993 Jun;7(2):119-21 [7687454.001]
  • [Cites] Hum Pathol. 1993 Aug;24(8):850-65 [8375856.001]
  • [Cites] Cancer Res. 1994 Jun 1;54(11):2837-40 [8187063.001]
  • [Cites] Am J Surg Pathol. 1995 Jun;19(6):659-65 [7755152.001]
  • [Cites] Cancer. 1996 Apr 1;77(7):1363-6 [8608516.001]
  • [Cites] J Pediatr Hematol Oncol. 1996 Aug;18(3):293-8 [8689345.001]
  • [Cites] Semin Diagn Pathol. 1996 Aug;13(3):204-12 [8875710.001]
  • [Cites] Am J Surg Pathol. 1997 Feb;21(2):219-25 [9042290.001]
  • [Cites] J Pediatr Hematol Oncol. 2000 Sep-Oct;22(5):446-50 [11037858.001]
  • (PMID = 16521199.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC4066136
  •  go-up   go-down


41. Fine RL, Shah SS, Moulton TA, Yu IR, Fogelman DR, Richardson M, Burris HA, Samuels BL, Assanasen C, Gorroochurn P, Hibshoosh H, Orjuela M, Garvin J, Goldman FD, Dubovsky D, Walterhouse D, Halligan G: Androgen and c-Kit receptors in desmoplastic small round cell tumors resistant to chemotherapy: novel targets for therapy. Cancer Chemother Pharmacol; 2007 Mar;59(4):429-37
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Androgen and c-Kit receptors in desmoplastic small round cell tumors resistant to chemotherapy: novel targets for therapy.
  • PURPOSE: Desmoplastic small round cell tumor (DSRCT) is a highly fatal, mainly peritoneal cell origin cancer which predominantly affects young adult males.
  • All patients had failed at least two prior multi-agent chemotherapy regimens and 44% had progressed after autologous stem cell transplant.
  • [MeSH-major] Carcinoma, Small Cell / chemistry. Proto-Oncogene Proteins c-kit / analysis. Receptors, Androgen / analysis. Soft Tissue Neoplasms / chemistry
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Female. Humans. Immunohistochemistry. Infant. Male. Middle Aged. Receptor, ErbB-2 / analysis

  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16896931.001).
  • [ISSN] 0344-5704
  • [Journal-full-title] Cancer chemotherapy and pharmacology
  • [ISO-abbreviation] Cancer Chemother. Pharmacol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Receptors, Androgen; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit; EC 2.7.10.1 / Receptor, ErbB-2
  •  go-up   go-down


42. Rekhi B, Basak R, Desai SB, Jambhekar NA: A t (11; 22) (p13; q12) EWS-WT 1 positive desmoplastic small round cell tumor of the maxilla: an unusual case indicating the role of molecular diagnosis in round cell sarcomas. J Postgrad Med; 2010 Jul-Sep;56(3):201-5
Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A t (11; 22) (p13; q12) EWS-WT 1 positive desmoplastic small round cell tumor of the maxilla: an unusual case indicating the role of molecular diagnosis in round cell sarcomas.
  • A desmoplastic small round cell tumor (DSRCT) is an uncommon tumor characterized by polyphenotypic expression and a specific reciprocal translocation t (11;.
  • Herein, we describe a DSRCT in the maxilla of a young man, who was initially diagnosed with a primitive neuroectodermal tumor (PNET), based on histopathological appearance of a round cell tumor, with MIC2 and -FLI-1 positivity, on immunohistochemistry (IHC).
  • The case is presented to highlight the value of molecular diagnosis in round cell sarcomas at uncommon sites, especially when similar IHC markers can be expressed in a PNET and a DSRCT.
  • An exact diagnosis of a round cell sarcoma has a therapeutic relevance.
  • [MeSH-major] Maxillary Neoplasms / diagnosis. Neuroectodermal Tumors, Primitive / diagnosis. Oncogene Proteins, Fusion / genetics. Sarcoma, Small Cell / diagnosis
  • [MeSH-minor] Adult. Antineoplastic Agents / administration & dosage. Base Sequence. Biomarkers, Tumor / analysis. Biomarkers, Tumor / genetics. Diagnosis, Differential. Humans. Male. Molecular Sequence Data. Translocation, Genetic

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20739766.001).
  • [ISSN] 0972-2823
  • [Journal-full-title] Journal of postgraduate medicine
  • [ISO-abbreviation] J Postgrad Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Biomarkers, Tumor; 0 / EWS1-WT1 fusion protein, human; 0 / Oncogene Proteins, Fusion
  •  go-up   go-down


43. Schlauder SM, Steffensen TS, Morgan M, Letson DG, Pledger WJ, Ma L, Bui MM: Assessment of muscarinic and nicotinic acetylcholine receptor expression in primitive neuroectodermal tumor/ewing family of tumor and desmoplastic small round cell tumor: an immunohistochemical and Western blot study of tissue microarray and cell lines. Fetal Pediatr Pathol; 2008;27(2):83-97
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Assessment of muscarinic and nicotinic acetylcholine receptor expression in primitive neuroectodermal tumor/ewing family of tumor and desmoplastic small round cell tumor: an immunohistochemical and Western blot study of tissue microarray and cell lines.
  • The primitive neuroectodermal tumor (PNET)/Ewing family of tumors (EFT) and desmoplastic small round cell tumor (DSRCT) portend a grave prognosis.
  • The Western blot analysis of 3 human Ewing sarcoma cell lines confirms the presence of AChRs.
  • [MeSH-major] Bone Neoplasms / metabolism. Brain Neoplasms / metabolism. Neuroectodermal Tumors, Primitive / metabolism. Receptors, Muscarinic / metabolism. Receptors, Nicotinic / metabolism. Sarcoma, Ewing / metabolism. Sarcoma, Small Cell / metabolism
  • [MeSH-minor] Adolescent. Adult. Aged. Biomarkers, Tumor / metabolism. Blotting, Western. Cell Line, Tumor. Child. Female. Fluorescent Antibody Technique, Indirect. Humans. Image Processing, Computer-Assisted. Male. Middle Aged. Retrospective Studies. Tissue Array Analysis


44. Dimitrakopoulou-Strauss A, Hohenberger P, Ströbel P, Marx A, Strauss LG: A recent application of fluoro-18-deoxyglucose positron emission tomography, treatment monitoring with a mammalian target of rapamycin inhibitor: an example of a patient with a desmoplastic small round cell tumor. Hell J Nucl Med; 2007 May-Aug;10(2):77-9
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A recent application of fluoro-18-deoxyglucose positron emission tomography, treatment monitoring with a mammalian target of rapamycin inhibitor: an example of a patient with a desmoplastic small round cell tumor.
  • A 36-year-old female patient with metastasized desmoplastic small round cells tumor after a broad surgical resection of the tumor area and due to related enzyme findings, was treated with the mTOR-inhibitor everolimus (Certican, Novartis, Basel, Switzerland) at an initial dose of 3 x 0.5 mg per day targeting at a blood level of >11 ng/ml.
  • [MeSH-minor] Adult. Female. Glucose Transport Proteins, Facilitative / pharmacokinetics. Humans. Neoplasm Metastasis. Signal Transduction


45. George S, Vaideeswar P, Pandit S, Kane S, Khandeparkar J: Malignant small round cell tumor of the heart: a diagnostic dilemma. Cardiovasc Pathol; 2007 Jan-Feb;16(1):56-8
Genetic Alliance. consumer health - Heart tumor.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant small round cell tumor of the heart: a diagnostic dilemma.
  • We report a rare malignant small round cell tumor of the heart in a 26-year-old woman.
  • Immunohistochemistry revealed divergent differentiation; hence, the tumor was designated as desmoplastic small round cell tumor.
  • This is the first report of such a tumor in the heart.
  • [MeSH-major] Carcinoma, Small Cell / diagnosis. Heart Neoplasms / diagnosis
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Diagnosis, Differential. Fatal Outcome. Female. Humans. Myxoma / diagnosis. Ovarian Neoplasms / diagnosis. Ovarian Neoplasms / secondary

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17218216.001).
  • [ISSN] 1054-8807
  • [Journal-full-title] Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology
  • [ISO-abbreviation] Cardiovasc. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down


46. Chao J, Budd GT, Chu P, Frankel P, Garcia D, Junqueira M, Loera S, Somlo G, Sato J, Chow WA: Phase II clinical trial of imatinib mesylate in therapy of KIT and/or PDGFRalpha-expressing Ewing sarcoma family of tumors and desmoplastic small round cell tumors. Anticancer Res; 2010 Feb;30(2):547-52
Hazardous Substances Data Bank. IMATINIB MESYLATE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Phase II clinical trial of imatinib mesylate in therapy of KIT and/or PDGFRalpha-expressing Ewing sarcoma family of tumors and desmoplastic small round cell tumors.
  • BACKGROUND: We have previously shown that the receptor tyrosine kinases, KIT and PDGFRalpha, are expressed on ESFT cell lines, and that imatinib induces dose-dependent apoptosis (1).
  • PATIENTS AND METHODS: Patients were selected for tumor immunohisto-chemical expression > or =2+/4+ for KIT or PDGFRalpha.
  • [MeSH-major] Abdominal Neoplasms / drug therapy. Bone Neoplasms / drug therapy. Carcinoma, Small Cell / drug therapy. Piperazines / therapeutic use. Proto-Oncogene Proteins c-kit / metabolism. Pyrimidines / therapeutic use. Receptor, Platelet-Derived Growth Factor beta / metabolism. Sarcoma, Ewing / drug therapy
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Antineoplastic Agents / therapeutic use. Benzamides. Female. Humans. Imatinib Mesylate. Male. Middle Aged. Neuroectodermal Tumors, Primitive / drug therapy. Neuroectodermal Tumors, Primitive / metabolism. Neuroectodermal Tumors, Primitive / pathology. Survival Rate. Treatment Outcome

  • Genetic Alliance. consumer health - Ewing's Sarcoma.
  • MedlinePlus Health Information. consumer health - Bone Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20332468.001).
  • [ISSN] 1791-7530
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Benzamides; 0 / Piperazines; 0 / Pyrimidines; 8A1O1M485B / Imatinib Mesylate; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit; EC 2.7.10.1 / Receptor, Platelet-Derived Growth Factor beta
  •  go-up   go-down


47. de Almeida LS, Requena L, Rütten A, Kutzner H, Garbe C, Pestana D, Gomes MM: Desmoplastic malignant melanoma: a clinicopathologic analysis of 113 cases. Am J Dermatopathol; 2008 Jun;30(3):207-15
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic malignant melanoma: a clinicopathologic analysis of 113 cases.
  • Desmoplastic melanoma (DM) is a rare variant of spindle cell melanoma, which usually develops in sun-damaged skin of elderly patients.
  • Fifty-one cases (45%) were classified as "pure DM" when the lesion was entirely desmoplastic, and 62 cases (55%) were considered as "combined DM" when a recognizable desmoplastic component was seen in an otherwise conventional malignant melanoma.
  • Seventy-one percent of the cases were histologically amelanotic, 23% showed a small amount of pigment, and only 6% were heavily pigmented.
  • The predominant neoplastic cells consisted of spindle-shaped melanocytes in 85% of the cases, whereas the remaining 15% of the cases demonstrated round neoplastic cells forming the main mass of the neoplasm.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / analysis. Female. Fibrosis. Follow-Up Studies. Humans. Immunohistochemistry. Male. Melanocytes / pathology. Middle Aged. Mitotic Index. Neoplasm Recurrence, Local. S100 Proteins / analysis. Survival Rate. Vimentin / analysis

  • MedlinePlus Health Information. consumer health - Melanoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18496419.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / S100 Proteins; 0 / Vimentin
  •  go-up   go-down


48. Ramalingam P, Teague D, Reid-Nicholson M: Imprint cytology of high-grade immature ovarian teratoma: a case report, literature review, and distinction from other ovarian small round cell tumors. Diagn Cytopathol; 2008 Aug;36(8):595-9
MedlinePlus Health Information. consumer health - Ovarian Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Imprint cytology of high-grade immature ovarian teratoma: a case report, literature review, and distinction from other ovarian small round cell tumors.
  • Differential diagnoses include other small round cell neoplasms such as ovarian neuroblastoma, small cell carcinoma of hypercalcemic type, primitive neuroectodermal tumor, Wilm's tumor, desmoplastic small round cell tumor, and Non-Hodgkin lymphoma.
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Neural Plate / pathology

  • Genetic Alliance. consumer health - Teratoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18618728.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 17
  •  go-up   go-down


49. Wang H, Zheng J, Wang YP, Yang Y, You JF: Molecular detection of EWS-Ets fusion transcripts and their clinicopathologic significance in Ewing's sarcoma/peripheral primitive neuroectodermal tumor. Chin Med J (Engl); 2005 Aug 20;118(16):1323-9
Genetic Alliance. consumer health - Ewing's Sarcoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Molecular detection of EWS-Ets fusion transcripts and their clinicopathologic significance in Ewing's sarcoma/peripheral primitive neuroectodermal tumor.
  • BACKGROUND: Ewing's sarcoma/peripheral primitive neuroectodermal tumor (ES/pPNET) is often difficult to distinguish from other small round cell tumors.
  • The EWS-Ets gene fusions that result from chromosomal translocations in this tumor provide potential molecular diagnostic markers.
  • Thirteen cases of other tumors with small round cell features (including rhabdomyosarcoma, neuroblastoma, lymphoma, small cell carcinoma, and desmoplastic small round cell tumor) were used as negative controls.
  • [MeSH-minor] Adolescent. Adult. Child. Female. Humans. Male. Middle Aged. Polymerase Chain Reaction. Proto-Oncogene Protein c-fli-1. RNA-Binding Protein EWS

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16157025.001).
  • [ISSN] 0366-6999
  • [Journal-full-title] Chinese medical journal
  • [ISO-abbreviation] Chin. Med. J.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / EWS-ERG fusion protein, human; 0 / EWS-FLI fusion protein; 0 / Oncogene Proteins, Fusion; 0 / Proto-Oncogene Protein c-fli-1; 0 / RNA, Messenger; 0 / RNA-Binding Protein EWS; 0 / Transcription Factors
  •  go-up   go-down


50. Fraser CJ, Weigel BJ, Perentesis JP, Dusenbery KE, DeFor TE, Baker KS, Verneris MR: Autologous stem cell transplantation for high-risk Ewing's sarcoma and other pediatric solid tumors. Bone Marrow Transplant; 2006 Jan;37(2):175-81
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Autologous stem cell transplantation for high-risk Ewing's sarcoma and other pediatric solid tumors.
  • The prognosis for many pediatric and young adult patients with solid tumors that have metastasized at the time of diagnosis or have relapsed after therapy remains very poor.
  • The steep dose-response curve of many of these tumors to alkylating agents makes myeloablative chemotherapy followed by autologous stem cell transplantation (ASCT) an attractive potential therapy.
  • Patients with a diagnosis of Ewing's sarcoma (ES) or desmoplastic small round cell tumor (DSRCT) had significantly better survival than those with other diagnoses with estimated 3-year OS of 54% (95% CI: 29-79%) for this group of patients (P = 0.03).
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Disease-Free Survival. Female. Fibroma, Desmoplastic / complications. Fibroma, Desmoplastic / mortality. Fibroma, Desmoplastic / pathology. Fibroma, Desmoplastic / therapy. Follow-Up Studies. Hepatic Veno-Occlusive Disease / etiology. Hepatic Veno-Occlusive Disease / mortality. Humans. Male. Risk Factors. Stem Cell Transplantation / methods. Stem Cell Transplantation / mortality. Survival Rate. Transplantation, Autologous

  • Genetic Alliance. consumer health - Ewing's Sarcoma.
  • Genetic Alliance. consumer health - Transplantation.
  • MedlinePlus Health Information. consumer health - Bone Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16273111.001).
  • [ISSN] 0268-3369
  • [Journal-full-title] Bone marrow transplantation
  • [ISO-abbreviation] Bone Marrow Transplant.
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  •  go-up   go-down


51. Anderson PM, Pearson M: Novel therapeutic approaches in pediatric and young adult sarcomas. Curr Oncol Rep; 2006 Jul;8(4):310-5
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Novel therapeutic approaches in pediatric and young adult sarcomas.
  • Additional chemotherapy and biotherapy options to reduce tumor burden and prevent metastases include intra-arterial chemotherapy in osteosarcoma; intrapleural chemotherapy, aerosol 9-nitrocamptothecin, or protracted irinotecan and temozolomide in Ewing's sarcoma; continuous hyperthermic peritoneal perfusion for malignancy involving the peritoneum, such as desmoplastic small round cell tumor; and ifosfamide with muramyl tripeptide phosphatidyl ethanolamine liposomes in osteosarcoma.
  • [MeSH-minor] Adult. Child. Combined Modality Therapy. Humans. Hypothermia, Induced

  • MedlinePlus Health Information. consumer health - Cancer Chemotherapy.
  • MedlinePlus Health Information. consumer health - Soft Tissue Sarcoma.
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Ann Oncol. 2004 Mar;15(3):440-9 [14998846.001]
  • [Cites] Lancet Oncol. 2005 Feb;6(2):93-102 [15683818.001]
  • [Cites] J Clin Oncol. 2005 Mar 20;23(9):2004-11 [15774791.001]
  • [Cites] Leukemia. 2006 Jan;20(1):29-34 [16281063.001]
  • [Cites] J Surg Res. 2006 Mar;131(1):26-40 [16154153.001]
  • [Cites] Curr Oncol Rep. 2004 Jul;6(4):315-20 [15161588.001]
  • [Cites] Nat Med. 2004 Feb;10(2):145-7 [14745444.001]
  • [Cites] Int J Oncol. 2004 Sep;25(3):677-84 [15289869.001]
  • [Cites] Eur J Oncol Nurs. 2005 Mar;9(1):21-32 [15774338.001]
  • [Cites] Mayo Clin Proc. 2003 Feb;78(2):147-55 [12583525.001]
  • [Cites] J Clin Oncol. 2005 May 20;23(15):3597-604 [15908670.001]
  • [Cites] J Clin Oncol. 2005 Oct 1;23(28):7135-42 [16192597.001]
  • [Cites] Cancer. 1993 Nov 15;72(10):2963-9 [8221562.001]
  • [Cites] Semin Oncol. 2004 Dec;31(6 Suppl 13):182-90 [15717743.001]
  • [Cites] Semin Oncol. 2005 Dec;32(6 Suppl 9):S68-73 [16399436.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2005 Feb 1;61(2):492-8 [15667972.001]
  • [Cites] J Clin Oncol. 1995 Mar;13(3):631-6 [7884424.001]
  • [Cites] Int J Colorectal Dis. 1999 Apr;14(2):86-94 [10367253.001]
  • [Cites] J Clin Oncol. 2002 Mar 15;20(6):1677-82 [11896119.001]
  • [Cites] Int J Clin Oncol. 2005 Dec;10(6):438-40 [16369750.001]
  • [Cites] Curr Opin Gastroenterol. 2005 Mar;21(2):216-22 [15711216.001]
  • [Cites] Am J Med Genet. 2002 Oct 30;115(3):189-93 [12407700.001]
  • [Cites] Radiology. 2005 May;235(2):469-77 [15858089.001]
  • [Cites] Cancer. 1998 Oct 1;83(7):1433-9 [9762946.001]
  • [Cites] Support Care Cancer. 2004 Aug;12(8):543-9 [15221580.001]
  • [Cites] J Clin Oncol. 2003 May 15;21(10):2011-8 [12743156.001]
  • [Cites] Leuk Lymphoma. 2005 Sep;46(9):1287-94 [16109605.001]
  • [Cites] J Clin Oncol. 2004 Jan 15;22(2):300-6 [14722039.001]
  • [Cites] Clin Cancer Res. 1999 Sep;5(9):2316-23 [10499599.001]
  • [Cites] Orthop Clin North Am. 2006 Jan;37(1):15-22 [16311108.001]
  • [Cites] Cancer. 2004 Apr 1;100(7):1498-506 [15042685.001]
  • [Cites] Clin Cancer Res. 2005 Oct 1;11(19 Pt 1):6895-900 [16203780.001]
  • [Cites] Cancer Res. 2004 Jun 1;64(11):3731-6 [15172975.001]
  • [Cites] Cancer Res. 1999 Jul 15;59(14):3374-8 [10416597.001]
  • [Cites] Semin Diagn Pathol. 1996 Aug;13(3):171-83 [8875708.001]
  • [Cites] Acta Orthop Scand Suppl. 2004 Apr;75(311):21-8 [15188662.001]
  • [Cites] Tech Coloproctol. 2005 Jul;9(2):95-103 [16007367.001]
  • [Cites] Methods Mol Med. 2005;111:127-48 [15911977.001]
  • [Cites] Nat Clin Pract Oncol. 2005 Apr;2(4):196-201 [16264934.001]
  • [Cites] Methods Enzymol. 2005;391:71-97 [15721375.001]
  • [Cites] J Pediatr Hematol Oncol. 2005 Apr;27(4):215-8 [15838394.001]
  • [Cites] Clin Cancer Res. 2004 Feb 1;10 (3):840-8 [14871959.001]
  • [Cites] Oncology. 2004;67(3-4):231-42 [15557784.001]
  • [Cites] Radiology. 2005 Apr;235(1):289-98 [15798173.001]
  • [Cites] J Oncol Pharm Pract. 2005 Sep;11(3):111-9 [16390599.001]
  • [Cites] Int J Cancer. 2005 Sep 1;116(3):401-6 [15800948.001]
  • [Cites] Nutrition. 2002 Mar;18(3):217-21 [11882392.001]
  • [Cites] Leuk Lymphoma. 2003 Jun;44(6):997-1000 [12854901.001]
  • [Cites] Clin Cancer Res. 2005 Oct 1;11(19 Pt 1):6944-9 [16203786.001]
  • (PMID = 17254532.001).
  • [ISSN] 1523-3790
  • [Journal-full-title] Current oncology reports
  • [ISO-abbreviation] Curr Oncol Rep
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  • [Number-of-references] 50
  •  go-up   go-down


52. Jambhekar NA, Bagwan IN, Ghule P, Shet TM, Chinoy RF, Agarwal S, Joshi R, Amare Kadam PS: Comparative analysis of routine histology, immunohistochemistry, reverse transcriptase polymerase chain reaction, and fluorescence in situ hybridization in diagnosis of Ewing family of tumors. Arch Pathol Lab Med; 2006 Dec;130(12):1813-8
MedlinePlus Health Information. consumer health - Bone Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CONTEXT: The Ewing family of tumors are often difficult to distinguish from other malignant small round cell tumors, but more than 90% have EWS-FLI1 chimeric transcript, which acts as a potential molecular diagnostic marker.
  • OBJECTIVE: To do a comparative analysis of 32 cases with EWS-FLI1: Ewing family of tumors (n = 30), desmoplastic small round cell tumor (n = 1), and undifferentiated sarcoma (n = 1).
  • Histologic groups were typical Ewing sarcoma (n = 15), atypical Ewing sarcoma (n = 4), Askin Rosai tumors (n = 5), desmoplastic small round cell tumor (n = 1), undifferentiated sarcoma (n = 1), and cases diagnosed as malignant small round cell tumors on FNAC (n = 6).
  • All tumors except desmoplastic small round cell tumor and undifferentiated sarcoma were CD99 positive.
  • EWS-FLI1 by reverse transcriptase polymerase chain reaction was noted in 15 cases of typical Ewing sarcoma, 4 cases of atypical Ewing sarcoma, 5 cases of Askin Rosai tumor, and no cases of desmoplastic small round cell tumor or undifferentiated sarcoma.
  • With use of fluorescence in situ hybridization, EWS break was detected in 10 of 11 paraffin blocks used and was negative in desmoplastic small round cell tumor.
  • [MeSH-minor] Adolescent. Adult. Biopsy, Fine-Needle. Carcinoma, Small Cell / diagnosis. Child. Child, Preschool. DNA, Neoplasm / analysis. Diagnosis, Differential. Female. Humans. Infant. Male. Middle Aged. Oncogene Proteins, Fusion / analysis. Proto-Oncogene Protein c-fli-1 / analysis. RNA-Binding Protein EWS

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17149955.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm; 0 / EWS-FLI fusion protein; 0 / Oncogene Proteins, Fusion; 0 / Proto-Oncogene Protein c-fli-1; 0 / RNA-Binding Protein EWS
  •  go-up   go-down


53. Bond M, Bernstein ML, Pappo A, Schultz KR, Krailo M, Blaney SM, Adamson PC: A phase II study of imatinib mesylate in children with refractory or relapsed solid tumors: a Children's Oncology Group study. Pediatr Blood Cancer; 2008 Feb;50(2):254-8
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Imatinib mesylate is a small molecule inhibitor of certain tyrosine kinases, most notably the chimeric bcr-abl fusion protein found in CML.
  • Ewing sarcoma, osteosarcoma, neuroblastoma, desmoplastic small round cell, and synovial sarcomas often overexpress KIT or the PDGF receptor.
  • PROCEDURE: Patients less than 30 years of age with refractory or recurrent Ewing sarcoma, osteosarcoma, neuroblastoma, desmoplastic small round cell, synovial sarcomas or GIST were eligible.
  • Responses were assessed according to Response Evaluation Criteria in Solid Tumor (RECIST).
  • CONCLUSION: Imatinib as a single agent at a dose of 440 mg/m(2)/day demonstrated little or no activity as a single agent in children with relapsed or refractory Ewing sarcoma, osteosarcoma, neuroblastoma, or desmoplastic small round cell tumors.
  • [MeSH-minor] Adolescent. Adult. Benzamides. Bone Neoplasms / drug therapy. Carcinoma, Small Cell / drug therapy. Child. Child, Preschool. Female. Gastrointestinal Stromal Tumors / drug therapy. Humans. Imatinib Mesylate. Male. Neuroblastoma / drug therapy. Osteosarcoma / drug therapy. Sarcoma, Ewing / drug therapy. Sarcoma, Synovial / drug therapy

  • MedlinePlus Health Information. consumer health - Cancer Chemotherapy.
  • MedlinePlus Health Information. consumer health - Cancer in Children.
  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. IMATINIB MESYLATE .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2007 Wiley-Liss, Inc.
  • (PMID = 17262795.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / U10 CA 98543
  • [Publication-type] Clinical Trial, Phase II; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Benzamides; 0 / Piperazines; 0 / Pyrimidines; 8A1O1M485B / Imatinib Mesylate
  •  go-up   go-down


54. Makhlouf HR, Abdul-Al HM, Wang G, Goodman ZD: Calcifying nested stromal-epithelial tumors of the liver: a clinicopathologic, immunohistochemical, and molecular genetic study of 9 cases with a long-term follow-up. Am J Surg Pathol; 2009 Jul;33(7):976-83
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • There is a rare primary liver tumor that has been reported as "ossifying stromal-epithelial tumor" (3 cases), "desmoplastic nested spindle cell tumor" (4 cases), and "nested stromal-epithelial tumor" (6 cases).
  • Herein we report 9 cases of this tumor, including 3 previously reported, from the files of the Armed Forces Institute of Pathology.
  • The tumors ranged from 5.5 to 20 cm and had a characteristic histologic appearance with irregular, sharply circumscribed nests and islands of bland-appearing spindled to focally epithelioid cells, surrounded by a cellular desmoplastic stroma.
  • The tumor nests had focal psammoma-like calcifications with or without ossification.
  • Immunohistochemistry demonstrated at least focal positivity for keratin cocktail AE1/AE3/LP34 in all 9 cases, and Wilms tumor suppressor gene (7/7) with variable staining for other epithelial (except keratins 7 and 20), neural, and mesenchymal markers.
  • None of the tumors was positive for Ewing sarcoma-primitive neuroectodermal tumors, desmoplastic small round cell tumor, and SYT-SSX fusion transcript.
  • We propose the name "calcifying nested stromal and epithelial tumor" for this rare but distinctive clinicopathologic entity of uncertain histogenesis.
  • On the basis of currently available information, this tumor is best considered a low-grade malignancy.
  • [MeSH-minor] Adolescent. Adult. Biomarkers, Tumor / analysis. Calcinosis. Child, Preschool. Epithelial Cells / pathology. Female. Hepatectomy. Humans. Immunohistochemistry. Liver Transplantation. Male. Stromal Cells / pathology. Young Adult

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19363442.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down


55. Hartmann JT, Patel S: New drug developments for patients with metastatic soft tissue sarcoma. Curr Oncol Rep; 2005 Jul;7(4):300-6
MedlinePlus Health Information. consumer health - Soft Tissue Sarcoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Small round cell sarcomas (SRCT), such as Ewing/primitive neuroectodermal tumor, desmoplastic SRCT, and rhabdomyosarcoma, are chemotherapy-sensitive and potentially curable malignancies that are treated with multimodality dose-intensive neoadjuvant protocols regardless of size or overt metastatic disease.
  • However, the number of effective cytotoxic agents for the treatment of patients with metastatic so-called adult soft tissue sarcoma is limited, especially when patients have failed anthracycline- and ifosfamide-based chemotherapy.

  • Genetic Alliance. consumer health - Soft tissue sarcoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [RetractionIn] Curr Oncol Rep. 2012 Apr;14(2):220 [22371000.001]
  • [Cites] Anticancer Drugs. 2002 May;13 Suppl 1:S7-9 [12173492.001]
  • [Cites] J Clin Oncol. 2002 Mar 1;20(5):1329-34 [11870176.001]
  • [Cites] Cancer Treat Rep. 1976 Feb;60(2):199-203 [769974.001]
  • [Cites] J Pediatr Hematol Oncol. 2001 May;23(4):215-20 [11846299.001]
  • [Cites] Am J Clin Oncol. 2002 Dec;25(6):561-4 [12477998.001]
  • [Cites] Gynecol Oncol. 2003 Apr;89(1):48-51 [12694653.001]
  • [Cites] Eur J Cancer. 2003 Jun;39(9):1318-29 [12763223.001]
  • [Cites] J Clin Oncol. 2001 Mar 1;19(5):1248-55 [11230465.001]
  • [Cites] Cancer. 2003 Jun 1;97(11):2848-52 [12767099.001]
  • [Cites] Cancer Res. 2001 Mar 15;61(6):2579-82 [11289134.001]
  • [Cites] Eur J Cancer. 2002 Mar;38(4):556-9 [11872349.001]
  • [Cites] Invest New Drugs. 2002 Feb;20(1):129-32 [12003189.001]
  • [Cites] Expert Opin Investig Drugs. 2000 Jul;9(7):1545-51 [11060759.001]
  • [Cites] Ann Oncol. 2001 Sep;12(9):1281-8 [11697841.001]
  • [Cites] Anticancer Drugs. 2000 Jun;11(5):325-9 [10912948.001]
  • [Cites] Anticancer Res. 2003 Mar-Apr;23(2C):1899-901 [12820475.001]
  • [Cites] Cancer Chemother Pharmacol. 1995;36(3):263-5 [7781149.001]
  • [Cites] Drugs. 2005;65(2):167-78 [15631540.001]
  • [Cites] Eur J Cancer. 1999 Mar;35(3):410-2 [10448291.001]
  • [Cites] J Clin Oncol. 1987 Jun;5(6):840-50 [3585441.001]
  • [Cites] Cancer. 2003 Apr 15;97(8):1969-73 [12673725.001]
  • [Cites] J Clin Oncol. 2002 Apr 15;20(8):2181-8 [11956280.001]
  • [Cites] Invest New Drugs. 2003 Nov;21(4):481-6 [14586217.001]
  • [Cites] Anticancer Drugs. 1999 Jun;10(5):453-6 [10477164.001]
  • [Cites] Eur J Cancer. 2002 Mar;38(4):543-9 [11872347.001]
  • [Cites] Ann Oncol. 1995 Oct;6(8):847-9 [8589028.001]
  • [Cites] Clin Ter. 1999 Jan-Feb;150(1):17-20 [10367540.001]
  • [Cites] Cancer. 2004 Oct 1;101(7):1664-71 [15378498.001]
  • [Cites] J Clin Oncol. 2001 Jun 1;19(11):2937-47 [11387367.001]
  • [Cites] Cochrane Database Syst Rev. 2003;(3):CD003293 [12917960.001]
  • [Cites] Cancer. 1995 Dec 1;76(11):2248-52 [8635028.001]
  • [Cites] Anticancer Drugs. 1999 Nov;10(10):873-7 [10630354.001]
  • [Cites] Cancer. 2002 Jun 15;94(12):3225-9 [12115355.001]
  • [Cites] J Clin Oncol. 2004 Mar 1;22(5):890-9 [14990645.001]
  • [Cites] Clin Cancer Res. 2002 Feb;8(2):383-93 [11839653.001]
  • [Cites] Am J Clin Oncol. 1996 Dec;19(6):574-6 [8931674.001]
  • [Cites] J Clin Oncol. 2000 May;18(10):2081-6 [10811673.001]
  • [Cites] Cancer. 2003 Dec 15;98 (12 ):2693-9 [14669291.001]
  • [Cites] J Clin Oncol. 2001 Aug 1;19(15):3483-9 [11481354.001]
  • [Cites] Ann Oncol. 1994 Jul;5(6):539-42 [7918126.001]
  • [Cites] Cancer. 2002 Jun 15;94(12):3263-8 [12115359.001]
  • [Cites] Cancer Chemother Pharmacol. 1993;31 Suppl 2:S174-9 [8453693.001]
  • [Cites] J Clin Oncol. 1996 May;14(5):1526-31 [8622067.001]
  • [Cites] J Clin Oncol. 2001 Aug 1;19(15):3463-9 [11481351.001]
  • [Cites] J Clin Oncol. 2004 Apr 15;22(8):1480-90 [15084621.001]
  • [Cites] J Med Chem. 1984 Feb;27(2):196-201 [6694168.001]
  • [Cites] J Med Chem. 1986 Aug;29(8):1553-5 [3735324.001]
  • [Cites] Cancer. 1999 Nov 15;86(10):2034-7 [10570428.001]
  • [Cites] Eur J Cancer. 1998 Feb;34(3):422-3 [9640234.001]
  • [Cites] J Clin Oncol. 2002 Jun 15;20(12):2824-31 [12065559.001]
  • (PMID = 15946590.001).
  • [ISSN] 1523-3790
  • [Journal-full-title] Current oncology reports
  • [ISO-abbreviation] Curr Oncol Rep
  • [Language] eng
  • [Publication-type] Journal Article; Retracted Publication; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  • [Number-of-references] 59
  •  go-up   go-down


56. Kaygusuz G, Kuzu I: Friend leukemia virus integration-1 (FLI-1) expression in gastrointestinal stromal tumors. Turk J Gastroenterol; 2009 Jun;20(2):83-6
Genetic Alliance. consumer health - Gastrointestinal Stromal Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND/AIMS: Friend leukemia virus integration-1 expression has been shown in a variety of tumors, including vascular tumors, desmoplastic small round cell tumor, Merkel cell carcinoma, and lymphoblastic lymphoma, in addition to Ewing's sarcoma/primitive neuroectodermal tumor.
  • CONCLUSIONS: Friend leukemia virus integration-1 can be expressed in a variety of tumors, and is helpful in making the diagnosis of Ewing's sarcoma/primitive neuroectodermal tumor.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Gastrointestinal Stromal Tumors / metabolism. Gene Expression. Proto-Oncogene Protein c-fli-1 / metabolism
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19530039.001).
  • [ISSN] 2148-5607
  • [Journal-full-title] The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
  • [ISO-abbreviation] Turk J Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Turkey
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / FLI1 protein, human; 0 / Proto-Oncogene Protein c-fli-1
  •  go-up   go-down


57. Nakatsuka S, Oji Y, Horiuchi T, Kanda T, Kitagawa M, Takeuchi T, Kawano K, Kuwae Y, Yamauchi A, Okumura M, Kitamura Y, Oka Y, Kawase I, Sugiyama H, Aozasa K: Immunohistochemical detection of WT1 protein in a variety of cancer cells. Mod Pathol; 2006 Jun;19(6):804-14
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • WT1 was first identified as a tumor suppressor involved in the development of Wilms' tumor.
  • Because WT1 has been identified as a molecular target for cancer immunotherapy, immunohistochemical detection of WT1 in tumor cells has become an essential part of routine practice.
  • Staining for C-19 and 6F-H2 was found in 35-100 and 5-88% of the cases of each kind of tumor, respectively.
  • WT1-positive tumors included tumor of the stomach, prostate, and biliary and urinary systems, and malignant melanomas.
  • A majority of the positive cases showed diffuse or granular staining in the cytoplasm, whereas ovarian tumors and desmoplastic small round cell tumors frequently showed nuclear staining.
  • Western blot analysis showed that WT1 protein was predominantly expressed in the cytoplasm of the tumor cells in two cases of lung adenocarcinoma, supporting the intracytoplasmic staining for WT1 using immunohistochemistry.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / analysis. Blotting, Western. Child. Child, Preschool. Female. Humans. Male. Middle Aged

  • MedlinePlus Health Information. consumer health - Cancer in Children.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16547468.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / WT1 Proteins
  •  go-up   go-down


58. Sigauke E, Rakheja D, Maddox DL, Hladik CL, White CL, Timmons CF, Raisanen J: Absence of expression of SMARCB1/INI1 in malignant rhabdoid tumors of the central nervous system, kidneys and soft tissue: an immunohistochemical study with implications for diagnosis. Mod Pathol; 2006 May;19(5):717-25
MedlinePlus Health Information. consumer health - Kidney Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The histologic diagnosis of malignant rhabdoid tumor depends on identification of characteristic rhabdoid cells-large cells with eccentrically located nuclei and abundant, eosinophilic cytoplasm-and immunohistochemistry with antibodies to vimentin, keratin and epithelial membrane antigen.
  • In total, 12 brain, three renal and two soft tissue rhabdoid tumors were examined along with four glioblastomas, four pilocytic astrocytomas, four oligodendrogliomas, two ependymomas, two choroid plexus papillomas, five pituitary adenomas, four germinomas, four renal carcinomas with Xp11.2 translocations, two clear cell sarcomas, two Wilms' tumors, one renal medullary carcinoma, two desmoplastic small round cell tumors, two alveolar rhabdomyosarcomas, two embryonal rhabdomyosarcomas, one low-grade chondrosarcoma, two extraskeletal myxoid chondrosarcomas, one mesenchymal chondrosarcoma, four malignant peripheral nerve sheath tumors, five metastatic carcinomas and four epithelioid sarcomas, two primary and two metastatic.
  • [MeSH-major] Central Nervous System Neoplasms / pathology. DNA-Binding Proteins / biosynthesis. Kidney Neoplasms / pathology. Rhabdoid Tumor / pathology. Soft Tissue Neoplasms / pathology. Transcription Factors / biosynthesis
  • [MeSH-minor] Adolescent. Adult. Brain Neoplasms / metabolism. Brain Neoplasms / pathology. Child. Child, Preschool. Chromosomal Proteins, Non-Histone. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Infant. Infant, Newborn. Male. Middle Aged

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16528370.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Chromosomal Proteins, Non-Histone; 0 / DNA-Binding Proteins; 0 / SMARCB1 protein, human; 0 / Transcription Factors
  •  go-up   go-down


59. Cho KJ, Ro JY, Choi J, Choi SH, Nam SY, Kim SY: Mesenchymal neoplasms of the major salivary glands: clinicopathological features of 18 cases. Eur Arch Otorhinolaryngol; 2008 Jul;265 Suppl 1:S47-56
MedlinePlus Health Information. consumer health - Salivary Gland Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Schwannomas were the most common benign tumors (six cases), followed by lipomas (three cases), plexiform neurofibroma, hemangioma, desmoid tumor, and solitary fibrous tumor (one each).
  • The malignant tumors consisted of one dermatofibrosarcoma protuberans, synovial sarcoma, leiomyosarcoma, pleomorphic liposarcoma and desmoplastic small round cell tumor each.
  • Genetic analysis for fusion transcripts was conclusive in the diagnosis of desmoplastic small round cell tumor, which is extremely rare at this location.
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Immunohistochemistry. Infant. Lipoma / diagnosis. Lipoma / pathology. Male. Middle Aged. Parotid Neoplasms / diagnosis. Parotid Neoplasms / pathology. Solitary Fibrous Tumors / diagnosis. Solitary Fibrous Tumors / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Korean Med Sci. 2002 Feb;17(1):18-22 [11850583.001]
  • [Cites] Histopathology. 1996 Mar;28(3):261-4 [8729047.001]
  • [Cites] Eur Arch Otorhinolaryngol. 2002 Oct;259(9):470-3 [12386749.001]
  • [Cites] Am J Clin Pathol. 2000 Sep;114(3):345-53 [10989634.001]
  • [Cites] Diagn Mol Pathol. 1998 Feb;7(1):24-8 [9646031.001]
  • [Cites] Ann Diagn Pathol. 2004 Aug;8(4):233-6 [15290676.001]
  • [Cites] Mod Pathol. 2002 Oct;15(10):1020-31 [12379747.001]
  • [Cites] S Afr J Surg. 1998 Feb;36(1):32-4; discussion 34-5 [9601830.001]
  • [Cites] Am J Surg Pathol. 2002 Jul;26(7):823-35 [12131150.001]
  • [Cites] Pediatr Blood Cancer. 2007 Sep;49(3):274-9 [16685737.001]
  • [Cites] Ann Diagn Pathol. 2002 Dec;6(6):339-44 [12478482.001]
  • [Cites] Laryngol Rhinol Otol (Stuttg). 1986 Sep;65(9):485-91 [3784727.001]
  • [Cites] Int J Oral Maxillofac Surg. 2005 Jul;34(5):533-6 [16053874.001]
  • [Cites] Otolaryngol Head Neck Surg. 2004 May;130(5):586-92 [15138425.001]
  • [Cites] Int J Oral Maxillofac Surg. 2005 Sep;34(6):690-2 [16053897.001]
  • [Cites] Hum Pathol. 1999 Apr;30(4):430-5 [10208465.001]
  • [Cites] Am J Otolaryngol. 2004 Nov-Dec;25(6):432-7 [15547814.001]
  • [Cites] Head Neck. 1999 Mar;21(2):168-71 [10091987.001]
  • [Cites] Br J Oral Surg. 1975 Mar;12(3):298-301 [164883.001]
  • [Cites] Diagn Cytopathol. 2000 Oct;23(4):253-9 [11002367.001]
  • (PMID = 17934743.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


60. Bagatell R, Gore L, Egorin MJ, Ho R, Heller G, Boucher N, Zuhowski EG, Whitlock JA, Hunger SP, Narendran A, Katzenstein HM, Arceci RJ, Boklan J, Herzog CE, Whitesell L, Ivy SP, Trippett TM: Phase I pharmacokinetic and pharmacodynamic study of 17-N-allylamino-17-demethoxygeldanamycin in pediatric patients with recurrent or refractory solid tumors: a pediatric oncology experimental therapeutics investigators consortium study. Clin Cancer Res; 2007 Mar 15;13(6):1783-8
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE: Heat shock protein 90 (Hsp90) is essential for the posttranslational control of many regulators of cell growth, differentiation, and apoptosis.
  • We conducted a phase I trial of 17-AAG in pediatric patients with recurrent or refractory neuroblastoma, Ewing's sarcoma, osteosarcoma, and desmoplastic small round cell tumor to determine the maximum tolerated dose, define toxicity and pharmacokinetic profiles, and generate data about molecular target modulation.
  • [MeSH-minor] Adolescent. Adult. Antineoplastic Agents / administration & dosage. Antineoplastic Agents / adverse effects. Antineoplastic Agents / pharmacokinetics. Biomarkers, Tumor / analysis. Child. Child, Preschool. Female. Humans. Male. Maximum Tolerated Dose. Recurrence. Treatment Failure

  • MedlinePlus Health Information. consumer health - Cancer Chemotherapy.
  • MedlinePlus Health Information. consumer health - Cancer in Children.
  • MedlinePlus Health Information. consumer health - Children's Health.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Clin Cancer Res. 2007 Mar 15;13(6):1625-9 [17363512.001]
  • (PMID = 17363533.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Grant] United States / NCRR NIH HHS / RR / M01 RR-00069; United States / NCRR NIH HHS / RR / M01 RR-00082; United States / NCRR NIH HHS / RR / M01 RR-00095; United States / NCI NIH HHS / CA / U54 CA090821
  • [Publication-type] Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Benzoquinones; 0 / Biomarkers, Tumor; 0 / Lactams, Macrocyclic; 4GY0AVT3L4 / tanespimycin
  •  go-up   go-down


61. Su WT, Rutigliano DN, Gholizadeh M, Jarnagin WR, Blumgart LH, La Quaglia MP: Hepatic metastasectomy in children. Cancer; 2007 May 15;109(10):2089-92
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: Fifteen patients were identified during this period and primary malignancies included neuroblastoma (7), Wilms tumor (3), osteogenic sarcoma (2), malignant gastric epithelial tumor (1), and desmoplastic small round cell tumor (2).
  • In this small group of patients anatomic hepatectomy was associated with better local control compared with wedge resection.
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Humans. Infant. Neoplasm Recurrence, Local. Postoperative Complications. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2007 American Cancer Society
  • (PMID = 17410597.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


62. Karavasilis V, Seddon BM, Ashley S, Al-Muderis O, Fisher C, Judson I: Significant clinical benefit of first-line palliative chemotherapy in advanced soft-tissue sarcoma: retrospective analysis and identification of prognostic factors in 488 patients. Cancer; 2008 Apr 1;112(7):1585-91
MedlinePlus Health Information. consumer health - Soft Tissue Sarcoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Patients with Ewing sarcoma, rhabdomyosarcoma, desmoplastic small round cell tumor, and gastrointestinal stromal tumors were excluded from the study.
  • [MeSH-minor] Adolescent. Adult. Aged. Antineoplastic Combined Chemotherapy Protocols. Bone Neoplasms / drug therapy. Bone Neoplasms / secondary. Chemotherapy, Adjuvant. Female. Follow-Up Studies. Humans. Liver Neoplasms / drug therapy. Liver Neoplasms / secondary. Lung Neoplasms / drug therapy. Lung Neoplasms / secondary. Male. Middle Aged. Neoplasm Staging. Palliative Care. Prognosis. Prospective Studies. Retrospective Studies. Survival Rate

  • Genetic Alliance. consumer health - Soft tissue sarcoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18278813.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


63. Jeong YJ, Kim S, Kwak SW, Lee NK, Lee JW, Kim KI, Choi KU, Jeon TY: Neoplastic and nonneoplastic conditions of serosal membrane origin: CT findings. Radiographics; 2008 May-Jun;28(3):801-17; discussion 817-8; quiz 912
MedlinePlus Health Information. consumer health - CT Scans.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The possibility of desmoplastic small round cell tumor should be considered in children or young adults with multiple peritoneal masses and no identifiable primary malignancy.
  • [MeSH-minor] Adult. Aged. Connective Tissue. Diagnosis, Differential. Female. Humans. Male. Middle Aged

  • MedlinePlus Health Information. consumer health - Connective Tissue Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright RSNA, 2008.
  • (PMID = 18480485.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 61
  •  go-up   go-down


64. Kinra P, Pujahari AK: Desmoplastic small round cell tumor--abdomen. Indian J Pathol Microbiol; 2008 Jul-Sep;51(3):449-50
Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic small round cell tumor--abdomen.
  • [MeSH-major] Abdomen / pathology. Abdominal Neoplasms / diagnosis. Abdominal Neoplasms / pathology. Sarcoma, Small Cell / diagnosis. Sarcoma, Small Cell / pathology
  • [MeSH-minor] Adult. Antibiotics, Antineoplastic / therapeutic use. Antineoplastic Agents, Alkylating / therapeutic use. Antineoplastic Agents, Phytogenic / therapeutic use. Desmin / analysis. Drug Therapy, Combination. Humans. Keratins / analysis. Male

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18723992.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 0 / Antineoplastic Agents, Alkylating; 0 / Antineoplastic Agents, Phytogenic; 0 / Desmin; 68238-35-7 / Keratins
  •  go-up   go-down


65. Ryan A, Razak A, Graham J, Benson A, Rowe D, Haugk B, Verrill M: Desmoplastic small round-cell tumor of the pancreas. J Clin Oncol; 2007 Apr 10;25(11):1440-2
Hazardous Substances Data Bank. VINBLASTINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic small round-cell tumor of the pancreas.
  • [MeSH-major] Carcinoma, Small Cell / diagnosis. Pancreatic Neoplasms / diagnosis
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biopsy. Cyclophosphamide / administration & dosage. Diagnosis, Differential. Female. Humans. Tomography, X-Ray Computed. Vinblastine / administration & dosage. Vinblastine / analogs & derivatives

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • MedlinePlus Health Information. consumer health - Pancreatic Cancer.
  • Hazardous Substances Data Bank. CYCLOPHOSPHAMIDE .
  • Hazardous Substances Data Bank. VINORELBINE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17416866.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 5V9KLZ54CY / Vinblastine; 8N3DW7272P / Cyclophosphamide; Q6C979R91Y / vinorelbine
  •  go-up   go-down


66. Wang ZM, Xiao WB, Zheng SS: Desmoplastic small round cell tumor of the lung: case report. Chin Med J (Engl); 2007 Dec 20;120(24):2327-8
MedlinePlus Health Information. consumer health - Lung Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic small round cell tumor of the lung: case report.
  • [MeSH-major] Carcinoma, Small Cell / pathology. Lung Neoplasms / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Immunohistochemistry. Male

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18167230.001).
  • [ISSN] 0366-6999
  • [Journal-full-title] Chinese medical journal
  • [ISO-abbreviation] Chin. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  •  go-up   go-down


67. Thuret R, Renaudin K, Leclere J, Battisti S, Bouchot O, Theodore C: Uncommon malignancies: case 3. Paratesticular desmoplastic small round-cell tumor. J Clin Oncol; 2005 Sep 1;23(25):6253-5
MedlinePlus Health Information. consumer health - Testicular Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Uncommon malignancies: case 3. Paratesticular desmoplastic small round-cell tumor.
  • [MeSH-major] Carcinoma, Small Cell / pathology. Fibromatosis, Aggressive / pathology. Testicular Neoplasms / pathology
  • [MeSH-minor] Adult. Humans. Male. Neoplasm Metastasis. Orchiectomy. Tomography, X-Ray Computed

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16135493.001).
  • [ISSN] 0732-183X
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


68. Diao B, Li F, Li G, Chen Z, Bi C: Primary desmoplastic small round cell tumor of urinary bladder. J Clin Oncol; 2010 Jun 20;28(18):e291-4
MedlinePlus Health Information. consumer health - Bladder Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary desmoplastic small round cell tumor of urinary bladder.
  • [MeSH-major] Carcinoma, Small Cell / pathology. Peritoneal Neoplasms / pathology. Urinary Bladder Neoplasms / pathology
  • [MeSH-minor] Antineoplastic Agents / therapeutic use. Combined Modality Therapy. Cystectomy. Cystoscopy. Humans. Immunoenzyme Techniques. Male. Neoplasm Invasiveness. Prognosis. Tomography, X-Ray Computed. Young Adult

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [ErratumIn] J Clin Oncol. 2012 Aug 20;30(24):3035. Diao, Bo [added]
  • (PMID = 20458037.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  •  go-up   go-down


69. Afif H, Benouhoud N, Aichane A, Trombati N, Bouayad Z: [Lung metastases of a small round cell desmoplastic tumor]. Rev Pneumol Clin; 2006 Feb;62(1):53-5
MedlinePlus Health Information. consumer health - Lung Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Lung metastases of a small round cell desmoplastic tumor].
  • [MeSH-major] Carcinoma, Small Cell / diagnosis. Lung Neoplasms / diagnosis. Peritoneal Neoplasms / secondary
  • [MeSH-minor] Adult. Humans. Male

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16604043.001).
  • [ISSN] 0761-8417
  • [Journal-full-title] Revue de pneumologie clinique
  • [ISO-abbreviation] Rev Pneumol Clin
  • [Language] fre
  • [Publication-type] Case Reports; Letter
  • [Publication-country] France
  •  go-up   go-down


70. Gorospe L, Gómez T, González LM, López A: Desmoplastic small round cell tumor of the pelvis: MRI findings with histopathologic correlation. Eur Radiol; 2007 Jan;17(1):287-8
MedlinePlus Health Information. consumer health - MRI Scans.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic small round cell tumor of the pelvis: MRI findings with histopathologic correlation.
  • [MeSH-minor] Adult. Humans. Male

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Radiology. 1999 Mar;210(3):633-8 [10207460.001]
  • [Cites] Am J Surg Pathol. 2002 Jul;26(7):823-35 [12131150.001]
  • [Cites] J Comput Assist Tomogr. 2002 Jul-Aug;26(4):579-83 [12218823.001]
  • [Cites] Am J Surg Pathol. 1991 Jun;15(6):499-513 [1709557.001]
  • (PMID = 16534600.001).
  • [ISSN] 0938-7994
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Germany
  •  go-up   go-down


71. Sun PP, Li J, Liang ZY: [Desmoplastic small round cell tumor of ovarian: report of a case]. Zhonghua Bing Li Xue Za Zhi; 2010 Mar;39(3):197-8
MedlinePlus Health Information. consumer health - Ovarian Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Desmoplastic small round cell tumor of ovarian: report of a case].
  • [MeSH-major] Desmoplastic Small Round Cell Tumor / pathology. Ovarian Neoplasms / pathology
  • [MeSH-minor] Adult. Antigens, CD / metabolism. Cell Adhesion Molecules / metabolism. Desmin / metabolism. Diagnosis, Differential. Female. Humans. Neoplasm Recurrence, Local. Neuroblastoma / metabolism. Neuroblastoma / pathology. Phosphopyruvate Hydratase / metabolism. Rhabdomyosarcoma, Embryonal / metabolism. Rhabdomyosarcoma, Embryonal / pathology. Sarcoma, Ewing / metabolism. Sarcoma, Ewing / pathology. Vimentin / metabolism

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20450770.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / CD99 protein, human; 0 / Cell Adhesion Molecules; 0 / Desmin; 0 / Vimentin; EC 4.2.1.11 / Phosphopyruvate Hydratase
  •  go-up   go-down


72. Yoon M, Desai K, Fulton R, Bucci K, Russin M, Conway RM, O'Brien JM: Desmoplastic small round cell tumor: a potentially lethal neoplasm manifesting in the orbit with associated visual symptoms. Arch Ophthalmol; 2005 Apr;123(4):565-7
MedlinePlus Health Information. consumer health - Vision Impairment and Blindness.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic small round cell tumor: a potentially lethal neoplasm manifesting in the orbit with associated visual symptoms.
  • [MeSH-major] Carcinoma, Small Cell / pathology. Orbital Neoplasms / pathology. Vision Disorders / diagnosis
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Humans. In Situ Hybridization, Fluorescence. Magnetic Resonance Imaging. Male

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15824236.001).
  • [ISSN] 0003-9950
  • [Journal-full-title] Archives of ophthalmology (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down


73. Sankhala KK, Chawla SP: Review: desmoplastic small round cell tumor: current treatment approach and role of targeted therapy. Clin Adv Hematol Oncol; 2009 Jul;7(7):476-8
Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Review: desmoplastic small round cell tumor: current treatment approach and role of targeted therapy.
  • [MeSH-minor] Adolescent. Antibodies, Monoclonal / therapeutic use. Antineoplastic Agents, Alkylating / therapeutic use. Child. Chromosomes, Human, Pair 11 / genetics. Chromosomes, Human, Pair 22 / genetics. Genes, Wilms Tumor. Humans. RNA-Binding Protein EWS / genetics. Receptor, ErbB-2 / metabolism. Translocation, Genetic. Young Adult

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19701156.001).
  • [ISSN] 1543-0790
  • [Journal-full-title] Clinical advances in hematology & oncology : H&O
  • [ISO-abbreviation] Clin Adv Hematol Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antineoplastic Agents, Alkylating; 0 / RNA-Binding Protein EWS; EC 2.7.10.1 / Receptor, ErbB-2
  • [Number-of-references] 31
  •  go-up   go-down


74. Khalbuss WE, Bui M, Loya A: A 19-year-old woman with a cervicovaginal mass and elevated serum CA 125. Desmoplastic small round cell tumor. Arch Pathol Lab Med; 2006 Apr;130(4):e59-61
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A 19-year-old woman with a cervicovaginal mass and elevated serum CA 125. Desmoplastic small round cell tumor.
  • [MeSH-major] CA-125 Antigen / blood. Carcinoma, Small Cell / secondary. Uterine Cervical Neoplasms / pathology. Vaginal Neoplasms / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Fatal Outcome. Female. Humans. Immunohistochemistry. Tomography, X-Ray Computed

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • MedlinePlus Health Information. consumer health - Cervical Cancer.
  • MedlinePlus Health Information. consumer health - Vaginal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16594762.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CA-125 Antigen
  •  go-up   go-down


75. Houet L, Möller I, Engelhardt M, Köhler G, Schmidt H, Herchenbach D, Schnitzler M, Schmitt-Graeff A, Jungbluth AA, Mertelsmann R, Rumstadt B, Waller CF: Long-term remission after CD34+-selected PBSCT in a patient with advanced intra-abdominal desmoplastic small round-cell tumor. Bone Marrow Transplant; 2010 Apr;45(4):793-5
Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term remission after CD34+-selected PBSCT in a patient with advanced intra-abdominal desmoplastic small round-cell tumor.
  • [MeSH-major] Bone Marrow Purging. Frizzled Receptors. Peripheral Blood Stem Cell Transplantation. Peritoneal Neoplasms / therapy. Receptors, G-Protein-Coupled. Soft Tissue Neoplasms / therapy
  • [MeSH-minor] Adult. Combined Modality Therapy. Humans. Transplantation, Autologous

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19718066.001).
  • [ISSN] 1476-5365
  • [Journal-full-title] Bone marrow transplantation
  • [ISO-abbreviation] Bone Marrow Transplant.
  • [Language] eng
  • [Publication-type] Case Reports; Letter; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / FZD9 protein, human; 0 / Frizzled Receptors; 0 / Receptors, G-Protein-Coupled
  •  go-up   go-down






Advertisement