[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 100 of about 290
1. Dekkers OM, Biermasz NR, Smit JW, Groot LE, Roelfsema F, Romijn JA, Pereira AM: Quality of life in treated adult craniopharyngioma patients. Eur J Endocrinol; 2006 Mar;154(3):483-9
MedlinePlus Health Information. consumer health - Brain Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Quality of life in treated adult craniopharyngioma patients.
  • A reduced QoL has been reported in childhood-onset craniopharyngioma; however, reports of QoL in adult craniopharyngioma patients are scarce.
  • In the present study, we assessed QoL in adult patients successfully treated for craniopharyngioma in our centre.
  • METHODS: In this study, we assessed QoL in 29 adult patients in remission during long-term follow-up after treatment for craniopharyngioma.
  • CONCLUSION: Adult patients treated for craniopharyngioma show persistent impairment in QoL, especially in the physical subscales.

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16498063.001).
  • [ISSN] 0804-4643
  • [Journal-full-title] European journal of endocrinology
  • [ISO-abbreviation] Eur. J. Endocrinol.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] England
  •  go-up   go-down


2. Garnett MR, Puget S, Grill J, Sainte-Rose C: Craniopharyngioma. Orphanet J Rare Dis; 2007;2:18
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Craniopharyngioma.
  • Craniopharyngiomas are benign slow growing tumours that are located within the sellar and para sellar region of the central nervous system.
  • Craniopharyngiomas are thought to arise from epithelial remnants of the craniopharyngeal duct or Rathke's pouch (adamantinomatous type) or from metaplasia of squamous epithelial cell rests that are remnants of the part of the stomadeum that contributed to the buccal mucosa (squamous papillary type).
  • The differential diagnosis includes other tumours in this region (pituitary adenoma), infectious or inflammatory processes (eosinophilic granuloma), vascular malformations (aneurysm) and congenital anomalies (Rathke's cleft cyst).
  • [MeSH-major] Craniopharyngioma / diagnosis. Craniopharyngioma / therapy. Pituitary Neoplasms / diagnosis. Pituitary Neoplasms / therapy
  • [MeSH-minor] Adult. Child. Diagnosis, Differential. Humans. Medical Oncology / methods. Prognosis. Quality of Life

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Childs Nerv Syst. 1999 Nov;15(11-12):764-9 [10603020.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1999 May 1;44(2):255-63 [10760417.001]
  • [Cites] J Clin Endocrinol Metab. 2006 Dec;91(12):4769-75 [16968795.001]
  • [Cites] J Neurosurg. 2007 Jan;106(1 Suppl):3-12 [17233305.001]
  • [Cites] Neurosurgery. 2001 Nov;49(5):1053-7; discussion 1057-8 [11846897.001]
  • [Cites] Acta Neurochir (Wien). 2002 Apr;144(4):403-4 [12021891.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2002 Jul 1;53(3):533-42 [12062594.001]
  • [Cites] J Neurosurg. 2002 Jul;97(1):1-2; discussion 2 [12134898.001]
  • [Cites] J Neurosurg. 2002 Jul;97(1):3-11 [12134929.001]
  • [Cites] Dev Med Child Neurol. 2004 Apr;46(4):220-9 [15077699.001]
  • [Cites] J Neurosurg. 1970 Dec;33(6):689-707 [5488801.001]
  • [Cites] Neurosurgery. 1982 Jul;11(1 Pt 1):12-5 [6287341.001]
  • [Cites] J Neurosurg. 1983 Sep;59(3):409-17 [6886754.001]
  • [Cites] J Neurol Neurosurg Psychiatry. 1984 Oct;47(10):1075-80 [6502164.001]
  • [Cites] Neurochirurgie. 1984;30(5):347-9 [6521815.001]
  • [Cites] Prog Exp Tumor Res. 1987;30:350-8 [3628817.001]
  • [Cites] Childs Nerv Syst. 1988 Apr;4(2):97-9 [3401877.001]
  • [Cites] J Neurosurg. 1990 Jul;73(1):3-11 [2352020.001]
  • [Cites] J Neurosurg. 1990 Oct;73(4):534-40 [2398383.001]
  • [Cites] Neurology. 1991 May;41(5):726-9 [2027490.001]
  • [Cites] J Neurosurg. 1991 Jun;74(6):1025-6 [2033440.001]
  • [Cites] Neurol Clin. 1991 May;9(2):453-65 [1944109.001]
  • [Cites] J Neurosurg. 1992 Jan;76(1):47-52 [1727168.001]
  • [Cites] Pediatr Neurosurg. 1994;21 Suppl 1:11-7 [7841069.001]
  • [Cites] Neurosurgery. 1994 Dec;35(6):1001-10; discussion 1010-1 [7885544.001]
  • [Cites] J Clin Endocrinol Metab. 1996 Jul;81(7):2734-7 [8675604.001]
  • [Cites] J Neurosurg. 1996 Jul;85(1):73-81 [8683285.001]
  • [Cites] J Neurosurg. 1998 Oct;89(4):547-51 [9761047.001]
  • [Cites] J Neurosurg. 1999 Feb;90(2):237-50 [9950494.001]
  • [Cites] Pediatr Hematol Oncol. 2005 Mar;22(2):89-101 [15804994.001]
  • [Cites] Neurosurg Focus. 2005 Jun 15;18(6A):E6 [16048292.001]
  • [Cites] Childs Nerv Syst. 2005 Aug;21(8-9):729-46 [16044343.001]
  • [Cites] Childs Nerv Syst. 2005 Aug;21(8-9):808-16 [16075214.001]
  • [Cites] Childs Nerv Syst. 2005 Aug;21(8-9):691-5 [16078079.001]
  • [Cites] Childs Nerv Syst. 2005 Aug;21(8-9):719-24 [16133276.001]
  • [Cites] J Pediatr Endocrinol Metab. 2006 Apr;19 Suppl 1:289-93 [16700303.001]
  • [Cites] J Pediatr Endocrinol Metab. 2006 Apr;19 Suppl 1:299-319 [16700305.001]
  • [Cites] J Pediatr Endocrinol Metab. 2006 Apr;19 Suppl 1:325-7 [16700307.001]
  • [Cites] J Pediatr Endocrinol Metab. 2006 Apr;19 Suppl 1:329-35 [16700308.001]
  • [Cites] J Pediatr Endocrinol Metab. 2006 Apr;19 Suppl 1:337-40 [16700309.001]
  • [Cites] J Pediatr Endocrinol Metab. 2006 Apr;19 Suppl 1:389-94 [16700315.001]
  • [Cites] J Pediatr Endocrinol Metab. 2006 Apr;19 Suppl 1:407-12 [16700318.001]
  • [Cites] Endocr Rev. 2006 Jun;27(4):371-97 [16543382.001]
  • (PMID = 17425791.001).
  • [ISSN] 1750-1172
  • [Journal-full-title] Orphanet journal of rare diseases
  • [ISO-abbreviation] Orphanet J Rare Dis
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 43
  • [Other-IDs] NLM/ PMC1855047
  •  go-up   go-down


3. Kendall-Taylor P, Jönsson PJ, Abs R, Erfurth EM, Koltowska-Häggström M, Price DA, Verhelst J: The clinical, metabolic and endocrine features and the quality of life in adults with childhood-onset craniopharyngioma compared with adult-onset craniopharyngioma. Eur J Endocrinol; 2005 Apr;152(4):557-67
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The clinical, metabolic and endocrine features and the quality of life in adults with childhood-onset craniopharyngioma compared with adult-onset craniopharyngioma.
  • BACKGROUND: Craniopharyngioma is a parasellar tumour that, although benign, tends to behave aggressively.
  • OBJECTIVES: To investigate the frequency and severity of problems associated with craniopharyngioma, using the large international database (KIMS) for adult patients with GH deficiency (GHD), and to assess the differences between the adult onset (AO, aged 18 or above) disease and adults with childhood onset (CO) craniopharyngioma.
  • DESIGN: Inclusion criteria were: an established diagnosis of craniopharyngioma, severe GHD and no recent GH treatment.
  • RESULTS: Peak age at onset of craniopharyngioma was 15-20 years.
  • Quality of life, assessed by Quality of Life-Assessment of Growth Hormone Deficiency in Adults (QoL-AGHDA) and the Nottingham Health Profile, was markedly reduced in all groups with no significant differences between them; the QoL-AGHDA score correlated with age at onset of both craniopharyngioma and GHD, and also with BMI in AO patients.
  • CONCLUSIONS: These data emphasise the generally poor state of health of patients treated for craniopharyngioma, with respect to endocrine and metabolic function, and also the markedly reduced quality of life.
  • Adults with CO craniopharyngioma were shorter, had lower IGF-I, lower BMI, less obesity and slightly lower blood lipid levels than patients with AO craniopharyngioma.

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15817911.001).
  • [ISSN] 0804-4643
  • [Journal-full-title] European journal of endocrinology
  • [ISO-abbreviation] Eur. J. Endocrinol.
  • [Language] ENG
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Lipids; 12629-01-5 / Human Growth Hormone; 67763-96-6 / Insulin-Like Growth Factor I
  •  go-up   go-down


Advertisement
4. Holmer H, Ekman B, Björk J, Nordstöm CH, Popovic V, Siversson A, Erfurth EM: Hypothalamic involvement predicts cardiovascular risk in adults with childhood onset craniopharyngioma on long-term GH therapy. Eur J Endocrinol; 2009 Nov;161(5):671-9
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hypothalamic involvement predicts cardiovascular risk in adults with childhood onset craniopharyngioma on long-term GH therapy.
  • CONTEXT: Craniopharyngioma patients without GH therapy are at an increased cardiovascular disease (CVD) risk and particularly concerning women.
  • No previous study on long-term GH therapy in adults with childhood onset (CO) craniopharyngioma was identified.
  • OBJECTIVE: To investigate CVD risk in adults with CO craniopharyngioma on complete hormone replacement, including long-term GH therapy, and to investigate the impact of disease-related factors on CVD risk.
  • DESIGN AND PARTICIPANTS: In a cross-sectional study of operated CO craniopharyngiomas (1958-2000) from a defined area of Sweden (2.5 million), we enrolled 42 patients (20 women) with a median age of 28 years (range 17-57) and assessed CVD risk of 20 (4-40) years after first operation.
  • Comparisons were made with matched controls and between patients with tumor growth into the third ventricle (TGTV) versus non-TGTV.
  • CONCLUSIONS: Adult patients with CO craniopharyngioma, especially those with TGTV, have persistently increased CVD risk.

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Hormone Replacement Therapy.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19667040.001).
  • [ISSN] 1479-683X
  • [Journal-full-title] European journal of endocrinology
  • [ISO-abbreviation] Eur. J. Endocrinol.
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Insulin; 0 / Leptin; 12629-01-5 / Human Growth Hormone
  •  go-up   go-down


5. Zantut-Wittmann DE, Garmes HM, Panzan AD, Lima Mde O, Baptista MT: Severe rhabdomyolysis due to adipsic hypernatremia after craniopharyngioma surgery. Arq Bras Endocrinol Metabol; 2007 Oct;51(7):1175-9
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Severe rhabdomyolysis due to adipsic hypernatremia after craniopharyngioma surgery.
  • The association of diabetes insipidus and adipsia after craniopharyngioma surgery has high morbidity.
  • CASE REPORT: This is the first report of a diabetic patient with craniopharyngioma who developed diabetes insipidus and adipsia after surgery, evolving with severe hypernatremia that caused considerable rhabdomyolysis.
  • [MeSH-major] Craniopharyngioma / surgery. Diabetes Insipidus / etiology. Hypernatremia / etiology. Pituitary Neoplasms / surgery. Rhabdomyolysis / etiology
  • [MeSH-minor] Administration, Intranasal. Adult. Creatine Kinase / blood. Dehydration. Drinking. Humans. Male. Postoperative Complications / therapy. Thirst

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • Genetic Alliance. consumer health - Rhabdomyolysis.
  • MedlinePlus Health Information. consumer health - Diabetes Insipidus.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18157396.001).
  • [ISSN] 0004-2730
  • [Journal-full-title] Arquivos brasileiros de endocrinologia e metabologia
  • [ISO-abbreviation] Arq Bras Endocrinol Metabol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
  • [Chemical-registry-number] EC 2.7.3.2 / Creatine Kinase
  •  go-up   go-down


6. Liu BG, Qi ST, Pan J, Peng YP, Fang LX: [Growth of craniopharyngioma involving the third ventricular floor in relation to the hypothalamus]. Nan Fang Yi Ke Da Xue Xue Bao; 2007 Mar;27(3):377-9
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Growth of craniopharyngioma involving the third ventricular floor in relation to the hypothalamus].
  • OBJECTIVE: To investigate the growth of craniopharyngioma involving the third ventricular floor with regard to the hypothalamus by detecting expressions of leukocyte common antigen (CD45) and intercellular adhesion molecule (ICAM-1) in the tumor tissue.
  • METHODS: The expressions of CD45 and ICAM-1 proteins in 30 craniopharyngioma samples with third ventricular floor involvement were detected by SP immunohistochemistry.
  • RESULTS: The inflammations labeled by CD45 were identified commonly in the craniopharyngioma tissues involving the third ventricular floor.
  • The expression of ICAM-1 was mainly in the inner tumor cells and interstitial cells, but not detected in the basilar tumor cells growing toward the third ventricular floor.
  • Adamantinomatous craniopharyngiomas showed markedly higher CD45 and ICAM-1 expressions than squamous papillary tumors (P<0.05).
  • CONCLUSION: Inflammatory adhesion largely characterizes the growth of the craniopharyngioma tissues involving the third ventricular floor toward the hypothalamus without the tendency of invasion.
  • The difference in the inflammation between the two types of craniopharyngioma may affect the prognosis of the patients.
  • [MeSH-major] Craniopharyngioma / pathology. Hypothalamus / pathology. Pituitary Neoplasms / pathology. Third Ventricle
  • [MeSH-minor] Adolescent. Adult. Aged. Antigens, CD45 / biosynthesis. Brain Neoplasms / metabolism. Brain Neoplasms / secondary. Child. Female. Humans. Immunohistochemistry. Intercellular Adhesion Molecule-1 / biosynthesis. Male. Middle Aged. Neoplasm Invasiveness

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17425998.001).
  • [ISSN] 1673-4254
  • [Journal-full-title] Nan fang yi ke da xue xue bao = Journal of Southern Medical University
  • [ISO-abbreviation] Nan Fang Yi Ke Da Xue Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 126547-89-5 / Intercellular Adhesion Molecule-1; EC 3.1.3.48 / Antigens, CD45
  •  go-up   go-down


7. Ujifuku K, Matsuo T, Takeshita T, Hayashi Y, Hayashi K, Kitagawa N, Hayashi T, Suyama K, Nagata I: Malignant transformation of craniopharyngioma associated with moyamoya syndrome. Neurol Med Chir (Tokyo); 2010;50(7):599-603
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant transformation of craniopharyngioma associated with moyamoya syndrome.
  • A 32-year-old man presented with malignant craniopharyngioma associated with moyamoya syndrome manifesting as right visual disturbance.
  • Magnetic resonance (MR) imaging revealed a parasellar mass lesion diagnosed as adamantinomatous craniopharyngioma.
  • MR imaging demonstrated tumor regrowth and bilateral occlusions of the internal carotid arteries (ICAs) with basal moyamoya phenomenon, which might have been induced by irradiation and/or tumor compression, 10 years after the initial manifestations.
  • Sufficient debulking was safely achieved via the transsphenoidal route and histological examination revealed squamous cell carcinoma, indicating malignant transformation of craniopharyngioma.
  • The tumor relapsed after only one month, so transsphenoidal tumor debulking was tried again.
  • Malignant transformation of craniopharyngioma may be included in moyamoya syndrome.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Cell Transformation, Neoplastic / pathology. Craniopharyngioma / pathology. Craniopharyngioma / surgery. Moyamoya Disease / pathology. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Neoplasms, Radiation-Induced / pathology. Neoplasms, Second Primary / pathology. Neoplasms, Second Primary / surgery. Pituitary Neoplasms / pathology. Pituitary Neoplasms / surgery. Postoperative Complications / pathology. Postoperative Complications / surgery
  • [MeSH-minor] Adult. Carotid Artery, Internal / pathology. Carotid Artery, Internal / surgery. Cerebral Angiography. Combined Modality Therapy. Fatal Outcome. Humans. Magnetic Resonance Imaging. Male. Microsurgery. Neuronavigation. Radiotherapy, Adjuvant. Reoperation

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - After Surgery.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20671391.001).
  • [ISSN] 1349-8029
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


8. Jiang ZL, Ren XH, Chu JS, Lin S, Zhang MZ: [Microsurgical treatment of adult craniopharyngiomas in 156 cases]. Zhonghua Yi Xue Za Zhi; 2010 Feb 2;90(5):291-4
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Microsurgical treatment of adult craniopharyngiomas in 156 cases].
  • OBJECTIVE: To explore the clinical features, surgical approaches and outcomes of craniopharyngioma in adults.
  • METHODS: A total of 156 cases of adult craniopharyngioma underwent microsurgery at our hospital were retrospectively reviewed and classified into four types according to the location of tumor relative to sellar diaphragm and the third ventricle.
  • 75.3% of the cases were capable of normal work and life and tumor recurred in 26 cases.
  • CONCLUSION: Selection of appropriate approach is the key to successful microsurgery for craniopharyngioma according to the site and growth pattern of tumor.
  • [MeSH-major] Craniopharyngioma / surgery. Microsurgery. Pituitary Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Male. Middle Aged. Retrospective Studies. Young Adult

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20368046.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  •  go-up   go-down


9. Jung TY, Jung S, Choi JE, Moon KS, Kim IY, Kang SS: Adult craniopharyngiomas: surgical results with a special focus on endocrinological outcomes and recurrence according to pituitary stalk preservation. J Neurosurg; 2009 Sep;111(3):572-7
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adult craniopharyngiomas: surgical results with a special focus on endocrinological outcomes and recurrence according to pituitary stalk preservation.
  • OBJECT: The aim of this study was to evaluate the results of surgical treatment of adult craniopharyngioma with a special focus on the endocrinological outcomes and tumor recurrence in cases of pituitary preservation.
  • METHODS: Between 1993 and February 2008, 41 patients underwent 47 surgical procedures for craniopharyngioma.
  • The tumor was totally removed in 36 procedures (76.6%), subtotally in 10 (21.3%), and partially in 1 (2.1%).
  • The rate of tumor recurrence was 24.4%.
  • The recurrence-free survival rate was significantly different between patients in whom complete tumor resection was accomplished and those in whom tumor resection was incomplete.
  • CONCLUSIONS: The pituitary stalk must be preserved with maximal tumor resection whenever possible to increase the chance of intact anterior pituitary function being maintained.
  • [MeSH-major] Craniopharyngioma / surgery. Pituitary Gland. Pituitary Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Disease-Free Survival. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Neurosurgical Procedures / methods. Postoperative Complications. Vision Disorders / etiology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19361259.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


10. Ragel BT, Bishop FS, Couldwell WT: Recurrent infrasellar clival craniopharyngioma. Acta Neurochir (Wien); 2007;149(7):729-30; discussion 730
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Recurrent infrasellar clival craniopharyngioma.
  • The patient is a 44-year-old man who underwent resection of a posterior nasopharynx tumor 12 years earlier via left lateral rhinotomy approach.
  • The final pathological analysis indicated the tumor was a craniopharyngioma, and the patient subsequently underwent focal radiation.
  • Magnetic resonance imaging revealed a clival mass, separate from the sella turcica, with imaging characteristics concerning for chordoma or primary bone tumor (Fig. 1).
  • The final pathological results indicated the tumor was adamantinomatous craniopharyngioma.
  • [MeSH-major] Cranial Fossa, Posterior / pathology. Craniopharyngioma / pathology. Pituitary Neoplasms / pathology
  • [MeSH-minor] Adult. Humans. Magnetic Resonance Imaging. Male. Nasopharynx / pathology. Nasopharynx / physiopathology. Nasopharynx / surgery. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / radiotherapy. Neoplasm Recurrence, Local / surgery. Pituitary Gland / pathology. Radiotherapy. Sella Turcica / pathology

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17533510.001).
  • [ISSN] 0001-6268
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Austria
  •  go-up   go-down


11. Zuccaro G: Radical resection of craniopharyngioma. Childs Nerv Syst; 2005 Aug;21(8-9):679-90
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radical resection of craniopharyngioma.
  • INTRODUCTION: The best management of craniopharyngioma in children remains a controversial topic among neurosurgeons.
  • The two treatments for craniopharyngioma most commonly discussed in the literature are primary total resection and limited resection followed by radiotherapy.
  • Without ignoring the challenging behavior of these tumors, we strongly believe that the first approach in a child with a craniopharyngioma is to attempt total removal.
  • Trying to remove a craniopharyngioma that has been treated previously with other methods is, in our experience, much more dangerous because of adherences of the tumor to vascular and neural structures.
  • Among the 153 patients, the tumor was prechiasmatic in 35 and retrochiasmatic in 112; in ten, these were considered giant forms, and eight had a posterior fossa extension.
  • None of our patients regarded as having undergone total tumor resection disclosed recurrence after a follow-up of 1-16 years.
  • CONCLUSIONS: The treatment of choice in craniopharyngioma in childhood is total resection in order to avoid radiation therapy and recurrence.
  • [MeSH-major] Craniopharyngioma / therapy. Hypophysectomy / methods. Pituitary Irradiation. Pituitary Neoplasms / therapy
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Combined Modality Therapy. Educational Status. Endocrine System Diseases / etiology. Female. Follow-Up Studies. Humans. Hydrocephalus / etiology. Infant. Infant, Newborn. Magnetic Resonance Imaging / methods. Male. Postoperative Complications. Retrospective Studies. Tomography, X-Ray Computed / methods. Treatment Outcome

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16133275.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


12. Niranjan A, Kano H, Mathieu D, Kondziolka D, Flickinger JC, Lunsford LD: Radiosurgery for craniopharyngioma. Int J Radiat Oncol Biol Phys; 2010 Sep 1;78(1):64-71
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radiosurgery for craniopharyngioma.
  • PURPOSE: To analyze the outcomes of gamma knife stereotactic radiosurgery (SRS) for residual or recurrent craniopharyngiomas and evaluate the factors that optimized the tumor control rates.
  • METHODS AND MATERIALS: A total of 46 patients with craniopharyngiomas underwent 51 SRS procedures at University of Pittsburgh between 1988 and 2007.
  • The median tumor volume was 1.0 cm(3) (range, 0.07-8.0).
  • The median prescription dose delivered to the tumor margin was 13.0 Gy (range, 9-20).
  • The 3- and 5-year progression-free survival rates (solid tumor control) were both 91.6%.
  • The overall local control rate (for both solid tumor and cyst control) was 91%, 81%, and 68% at 1, 3, and 5 years, respectively.
  • Two patients developed homonymous hemianopsia owing to tumor progression after SRS.
  • CONCLUSION: SRS is a safe and effective minimally invasive option for the management of residual or recurrent craniopharyngiomas.
  • Complete radiosurgical coverage of the tumor was associated with better tumor control.
  • [MeSH-major] Craniopharyngioma / surgery. Neoplasm Recurrence, Local / surgery. Pituitary Neoplasms / surgery. Radiosurgery / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Analysis of Variance. Child. Child, Preschool. Disease-Free Survival. Female. Hemianopsia / etiology. Humans. Male. Middle Aged. Neoplasm, Residual. Radiotherapy Dosage. Survival Rate. Treatment Outcome. Tumor Burden. Young Adult

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright (c) 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20005637.001).
  • [ISSN] 1879-355X
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


13. Rodriguez FJ, Scheithauer BW, Tsunoda S, Kovacs K, Vidal S, Piepgras DG: The spectrum of malignancy in craniopharyngioma. Am J Surg Pathol; 2007 Jul;31(7):1020-8
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The spectrum of malignancy in craniopharyngioma.
  • Craniopharyngiomas are low-grade epithelial neoplasms occurring almost exclusively in the sellar/suprasellar region.
  • Herein, we report 3 patients with craniopharyngiomas exhibiting histologic malignancy, 2 of which received radiation therapy before its appearance.
  • The latter developed after multiple recurrences and radiation therapy in 2 cases, but seemed to arise de novo in 1 case resembling odontogenic ghost cell carcinoma and lacking any definite low-grade craniopharyngioma precursor.
  • Malignant transformation in craniopharyngiomas, although rare, does exist.
  • De novo malignancy in odontogenic tumors of the sella is even more unusual, but also has an ominous prognosis.
  • [MeSH-major] Craniopharyngioma / pathology. Neoplasms, Second Primary / pathology. Pituitary Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Biomarkers, Tumor / analysis. Carcinoma, Squamous Cell / pathology. Cell Transformation, Neoplastic. Combined Modality Therapy. Fatal Outcome. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Radiotherapy, Adjuvant. Ubiquitin-Protein Ligases / analysis

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17592268.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 6.3.2.19 / MIB1 ligase, human; EC 6.3.2.19 / Ubiquitin-Protein Ligases
  •  go-up   go-down


14. Stamm AC, Vellutini E, Harvey RJ, Nogeira JF Jr, Herman DR: Endoscopic transnasal craniotomy and the resection of craniopharyngioma. Laryngoscope; 2008 Jul;118(7):1142-8
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic transnasal craniotomy and the resection of craniopharyngioma.
  • OBJECTIVES/HYPOTHESIS: To describe the utility of a large transnasal craniotomy and its reconstruction in the surgical management of patients with craniopharyngioma.
  • Patient characteristics (age, sex, follow-up), tumor factors (size, position extension, previous surgery), type of repair (pedicled mucosal flaps, free mucosal grafts), and outcomes (visual, endocrine, and surgical morbidity) were defined and sought in patients who had an entirely endoscopic resection of extensive craniopharyngioma (defined as requiring removal of the planum sphenoidale in addition to sella exposure in the approach).
  • RESULTS: Seven patients had an entirely endoscopic resection of extensive craniopharyngioma during the study period.
  • Mean tumor size was 3.2 cm (standard deviation +/- 2.0).
  • CONCLUSIONS: The endoscopic management of large craniopharyngioma emphasizes recent advancements in endoscopic skull base surgery.
  • [MeSH-major] Craniopharyngioma / surgery. Craniotomy / methods. Endoscopy / methods. Pituitary Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Child. Cohort Studies. Female. Follow-Up Studies. Humans. Image Processing, Computer-Assisted. Magnetic Resonance Imaging. Male. Middle Aged. Postoperative Complications / radiography. Postoperative Complications / surgery. Reoperation. Retrospective Studies. Skull Base / surgery. Sphenoid Sinus / radiography. Sphenoid Sinus / surgery. Tomography, X-Ray Computed. Treatment Outcome


15. Olowoyeye OA, Bankole OB: Craniopharyngioma causing visual loss in an adult. Nig Q J Hosp Med; 2008 Jan-Mar;18(1):30-1
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Craniopharyngioma causing visual loss in an adult.
  • Craniopharyngiomas are usually benign tumours, commonly seen in children.
  • This is a case of craniopharyngioma resulting in visual loss in an adult.
  • [MeSH-major] Blindness / etiology. Craniopharyngioma / complications. Pituitary Neoplasms / complications
  • [MeSH-minor] Adult. Hallucinations. Humans. Male. Tomography, Spiral Computed

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19062468.001).
  • [ISSN] 0189-2657
  • [Journal-full-title] Nigerian quarterly journal of hospital medicine
  • [ISO-abbreviation] Nig Q J Hosp Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Nigeria
  •  go-up   go-down


16. Shi XE, Wu B, Fan T, Zhou ZQ, Zhang YL: Craniopharyngioma: surgical experience of 309 cases in China. Clin Neurol Neurosurg; 2008 Feb;110(2):151-9
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Craniopharyngioma: surgical experience of 309 cases in China.
  • OBJECTIVE: The objective of the present study was to retrospectively review the surgical outcome of 309 craniopharyngioma cases treated by a single neurosurgeon in China.
  • PATIENTS AND METHODS: A total of 309 cases of craniopharyngioma that were treated surgically from January 1996 to May 2006.
  • The tumor size varied in diameter from 2.0 cm to 9.0 cm (mean 34.5 mm).
  • In the 167 patients with total tumor removal, 23 (13.7%) had tumor recurrence within an average of 1.8 years.
  • CONCLUSION: Pre-surgery neuroimaging evaluations have improved our knowledge of intricate anatomical relationship between craniopharyngioma and the structures of the hypothalamus, pituitary stalk, and optic apparatus, which make total tumor resection feasible with the preservation of these vital structures to ensure a lower recurrence rate with acceptable mortality.
  • However, excessive long-term morbidity, mostly related to hypopituitarism, which leads to the poor quality of life for the craniopharyngioma patients, is still remained.
  • Further effort should be invested to monitor and maintain the normal hormone levels, hence improve the quality of life for craniopharyngioma patients.
  • [MeSH-major] Craniopharyngioma / surgery. Pituitary Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. China. Cohort Studies. Female. Humans. Hypophysectomy. Infant. Male. Microsurgery. Middle Aged. Retrospective Studies. Treatment Outcome

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18063470.001).
  • [ISSN] 0303-8467
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  •  go-up   go-down


17. Merchant TE: Craniopharyngioma radiotherapy: endocrine and cognitive effects. J Pediatr Endocrinol Metab; 2006 Apr;19 Suppl 1:439-46
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Craniopharyngioma radiotherapy: endocrine and cognitive effects.
  • Potential existing and treatment associated deficits in neurological, endocrine and cognitive function influence treatment decisions and the use of radiation therapy in children with craniopharyngioma.
  • Early and accurate evaluation of these functions should be considered for all patients to provide parents and caregivers with the information necessary to plan intervention and mitigate the consequences of tumor and treatment.
  • [MeSH-major] Cognition Disorders / etiology. Craniopharyngioma / radiotherapy. Endocrine System Diseases / etiology. Pituitary Neoplasms / radiotherapy. Radiotherapy / adverse effects
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Combined Modality Therapy. Dopamine Agents. Female. Human Growth Hormone / blood. Human Growth Hormone / deficiency. Humans. Intelligence Tests. Levodopa. Male. Neuropsychological Tests. Pituitary Hormones / blood. Treatment Outcome

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Endocrine Diseases.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • MedlinePlus Health Information. consumer health - Radiation Therapy.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16700322.001).
  • [ISSN] 0334-018X
  • [Journal-full-title] Journal of pediatric endocrinology & metabolism : JPEM
  • [ISO-abbreviation] J. Pediatr. Endocrinol. Metab.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Dopamine Agents; 0 / Pituitary Hormones; 12629-01-5 / Human Growth Hormone; 46627O600J / Levodopa
  • [Number-of-references] 16
  •  go-up   go-down


18. Banczerowski P, Bálint K, Sipos L: Temporal extradural ectopic craniopharyngioma. Case report. J Neurosurg; 2007 Jul;107(1):178-80
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Temporal extradural ectopic craniopharyngioma. Case report.
  • A rare case of histologically confirmed primary craniopharyngioma at an ectopic location is presented.
  • This cystic tumor, which had a small solid portion, was located extradurally at the right temporobasal region, and pyramidal bone erosion was observed.
  • The neuroimaging findings, surgical intervention, and histopathological features of the tumor are discussed.
  • The authors' hypothesis regarding the extradural location of the tumor is that mismigration of squamous epithelial cell remnants of the obliterated craniopharyngeal canal had occurred.
  • [MeSH-major] Bone Diseases / complications. Bone Diseases / pathology. Craniopharyngioma / complications. Craniopharyngioma / pathology. Pituitary Gland. Pituitary Neoplasms / pathology. Temporal Bone / pathology
  • [MeSH-minor] Adult. Choristoma. Humans. Magnetic Resonance Imaging. Male

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Bone Diseases.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17639891.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


19. Krysiak R, Okopień B, Szkróbka W: [Etiology, histopathological picture and clinical presentation of craniopharyngioma]. Pol Merkur Lekarski; 2008 Aug;25(146):175-8
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Etiology, histopathological picture and clinical presentation of craniopharyngioma].
  • Craniopharyngioma is a rare, benign, suprasellar brain tumour accounting for about 1 to 3% of all intracranial neoplasms.
  • In this paper, the authors review different aspects of pathology, and clinical presentation of the craniopharyngiomas.
  • [MeSH-major] Craniopharyngioma / diagnosis. Craniopharyngioma / pathology. Pituitary Neoplasms / diagnosis. Pituitary Neoplasms / pathology
  • [MeSH-minor] Adult. Humans

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18942342.001).
  • [ISSN] 1426-9686
  • [Journal-full-title] Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego
  • [ISO-abbreviation] Pol. Merkur. Lekarski
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Poland
  • [Number-of-references] 27
  •  go-up   go-down


20. Bawden HN, Salisbury S, Eskes G, Morehouse R: Neuropsychological functioning following craniopharyngioma removal. J Clin Exp Neuropsychol; 2009 Jan;31(1):140-4
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neuropsychological functioning following craniopharyngioma removal.
  • The neuropsychological functioning of patients who had undergone surgical removal of craniopharyngiomas was compared to that of an endocrine control group composed of patients with nontumor hypopituitarism, an obese control group, and a normal control group.
  • The craniopharyngioma group had lower Performance IQ than did the normal control group, but their Performance IQ was comparable to that of the hypopituitarism and obese control groups.
  • The craniopharyngioma patients did not differ in Verbal or Full Scale IQs from the remaining groups.
  • The group mean scores on the measures of intelligence and neuropsychological abilities for the craniopharyngioma patients were in the low-average to average range.
  • While craniopharyngioma patients can have significant morbidity including endocrine and visual deficits as well as obesity resulting from hyperphagia, neuropsychological deficits are not always present.
  • [MeSH-major] Craniopharyngioma / physiopathology. Neuropsychological Tests. Pituitary Neoplasms / physiopathology
  • [MeSH-minor] Analysis of Variance. Attention / physiology. Female. Humans. Hypopituitarism / physiopathology. Intelligence. Male. Memory. Obesity / physiopathology. Problem Solving / physiology. Young Adult

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18608690.001).
  • [ISSN] 1744-411X
  • [Journal-full-title] Journal of clinical and experimental neuropsychology
  • [ISO-abbreviation] J Clin Exp Neuropsychol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


21. Mong S, Pomeroy SL, Cecchin F, Juraszek A, Alexander ME: Cardiac risk after craniopharyngioma therapy. Pediatr Neurol; 2008 Apr;38(4):256-60
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiac risk after craniopharyngioma therapy.
  • Although long-term survival after craniopharyngioma treatment is excellent in childhood and early adulthood, sudden deaths in two craniopharyngioma survivors with cardiac findings suggest a need to determine whether treated patients exhibit potential substrates for sudden cardiac death.
  • [MeSH-major] Craniopharyngioma / surgery. Death, Sudden, Cardiac / etiology. Long QT Syndrome / etiology. Pituitary Neoplasms / surgery. Postoperative Complications
  • [MeSH-minor] Adolescent. Adult. Cohort Studies. Electrocardiography. Female. Humans. Male. Retrospective Studies

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - After Surgery.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18358404.001).
  • [ISSN] 0887-8994
  • [Journal-full-title] Pediatric neurology
  • [ISO-abbreviation] Pediatr. Neurol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


22. Waber DP, Pomeroy SL, Chiverton AM, Kieran MW, Scott RM, Goumnerova LC, Rivkin MJ: Everyday cognitive function after craniopharyngioma in childhood. Pediatr Neurol; 2006 Jan;34(1):13-9
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Everyday cognitive function after craniopharyngioma in childhood.
  • Despite clinical impressions that cognitive complaints are prominent in patients with a history of craniopharyngioma, formal neuropsychologic documentation is inconsistent.
  • This study assessed everyday cognitive complaints and neuropsychologic test performance to evaluate the prevalence of problems and the relationship of these domains to one another in patients treated for craniopharyngioma in childhood or adolescence.
  • Ten patients treated for craniopharyngioma completed measures of everyday cognitive function (Cognitive Failures Questionnaire, Rivermead Behavioural Memory Test) and a battery of standard neuropsychologic tests.
  • Adolescents and young adults with treated craniopharyngioma experience deficits in everyday cognitive functions, many involving memory, that are not easily detected by standard neuropsychologic testing.
  • [MeSH-major] Activities of Daily Living / psychology. Cognition Disorders / etiology. Craniopharyngioma / psychology. Memory Disorders / etiology. Pituitary Neoplasms / psychology
  • [MeSH-minor] Adolescent. Adult. Follow-Up Studies. Humans. Neuropsychological Tests. Self-Assessment

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Memory.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16376272.001).
  • [ISSN] 0887-8994
  • [Journal-full-title] Pediatric neurology
  • [ISO-abbreviation] Pediatr. Neurol.
  • [Language] eng
  • [Grant] United States / NICHD NIH HHS / HD / P30-HD18655
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


23. Hashizume C, Mori Y, Kobayashi T, Shibamoto Y, Nagai A, Hayashi N: Stereotactic radiotherapy using Novalis for craniopharyngioma adjacent to optic pathways. J Neurooncol; 2010 Jun;98(2):239-47
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Stereotactic radiotherapy using Novalis for craniopharyngioma adjacent to optic pathways.
  • Craniopharyngioma has benign histological character.
  • This study aims to evaluate treatment results of Novalis stereotactic radiotherapy (SRT) for craniopharyngioma adjacent to optic pathways.
  • Ten patients (six men, four women) with craniopharyngioma and median age of 56.5 years (range 10-74 years) were treated by SRT using Novalis from July 2006 through March 2009.
  • Median volume of tumor was 7.9 ml (range 1.1-21 ml).
  • SRT for craniopharyngioma may be a safe and effective treatment.
  • Longer follow-up is necessary to determine long-term tumor control or late complications.
  • [MeSH-major] Craniopharyngioma / surgery. Optic Nerve Diseases / surgery. Pituitary Neoplasms / surgery. Radiosurgery / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Female. Follow-Up Studies. Humans. Image Processing, Computer-Assisted / methods. Magnetic Resonance Imaging / methods. Male. Middle Aged. Radiotherapy Dosage. Retrospective Studies. Treatment Outcome. Young Adult

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Optic Nerve Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20422439.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


24. Caceres A, Reitman AJ, Tomita T: Craniopharyngioma and Cushing disease: case report. J Neurosurg; 2005 Apr;102(3 Suppl):318-21
Hazardous Substances Data Bank. Corticotropin .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Craniopharyngioma and Cushing disease: case report.
  • Craniopharyngioma is a common sellar region tumor occurring in children.
  • Patients with craniopharyngioma commonly present with visual deficits and hydrocephalus.
  • The authors present the case of a child who presented with short stature and clinical evidence of Cushing disease (CD) associated with a suprasellar tumor.
  • The patient underwent insertion of an Ommaya reservoir into the tumor's cystic portion.
  • After adequate decompression of the tumor, the patient underwent total resection.
  • The tumor pathology was compatible with an adamantinomatous craniopharyngioma and immunohistochemical studies failed to show staining for ACTH.
  • [MeSH-major] Central Nervous System Cysts / surgery. Craniopharyngioma / surgery. Pituitary ACTH Hypersecretion / surgery. Pituitary Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adrenocorticotropic Hormone / blood. Adult. Child. Cyst Fluid / chemistry. Diagnosis, Differential. Dwarfism, Pituitary / etiology. Follow-Up Studies. Hemianopsia / etiology. Humans. Hypophysectomy. Hypopituitarism / etiology. Magnetic Resonance Imaging. Male. Obesity / etiology. Postoperative Complications / etiology. Tomography, X-Ray Computed

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15881759.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 9002-60-2 / Adrenocorticotropic Hormone
  •  go-up   go-down


25. Kim SD, Park JY, Park J, Lee JB, Kim SH, Lim DJ: Radiological findings following postsurgical intratumoral bleomycin injection for cystic craniopharyngioma. Clin Neurol Neurosurg; 2007 Apr;109(3):236-41
Hazardous Substances Data Bank. BLEOMYCIN .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radiological findings following postsurgical intratumoral bleomycin injection for cystic craniopharyngioma.
  • OBJECTIVES: The purpose of this study was to compare the radiological findings before and after intratumoral bleomycin injection in patients with cystic craniopharyngioma so as to define the role of adjuvant intracavitary bleomycin chemotherapy for cystic craniopharyngiomas.
  • PATIENTS AND METHODS: Eleven patients whose craniopharyngioma was confirmed cytologically and/or histologically were retrospectively reviewed.
  • Only the solid portion of the cystic craniopharyngiomas was excised before repeated injections of bleomycin (15-180 mg in total) into the cystic portion through an Ommaya reservoir were given.
  • RESULTS: After the completion of all treatment cycles, the disappearance or shrinkage of the tumor was initially noted in all cases on follow-up CT and/or MR imaging studies.
  • However, tumor recurrence was seen in four cases with a mixed tumor type.
  • CONCLUSION: Postoperative bleomycin injection in cystic craniopharyngioma does not appear to totally eradicate the tumor and does not stop tumor recurrence unless the cyst is the only portion of the craniopharyngioma that is left.
  • Nevertheless, postoperative bleomycin injection decreases and stabilizes tumor size, and thus may be considered as an option of treatment modalities in patients with predominantly cystic craniopharyngiomas.
  • [MeSH-major] Antibiotics, Antineoplastic / therapeutic use. Bleomycin / therapeutic use. Craniopharyngioma. Cysts. Magnetic Resonance Imaging. Pituitary Neoplasms. Tomography, X-Ray Computed
  • [MeSH-minor] Adolescent. Adult. Aged. Brain / pathology. Brain / radiography. Brain / surgery. Child. Combined Modality Therapy. Female. Humans. Injections. Male. Middle Aged. Neurosurgical Procedures. Postoperative Care

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - CT Scans.
  • MedlinePlus Health Information. consumer health - MRI Scans.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17046151.001).
  • [ISSN] 0303-8467
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 11056-06-7 / Bleomycin
  •  go-up   go-down


26. Roth CL, Hunneman DH, Gebhardt U, Stoffel-Wagner B, Reinehr T, Müller HL: Reduced sympathetic metabolites in urine of obese patients with craniopharyngioma. Pediatr Res; 2007 Apr;61(4):496-501
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Reduced sympathetic metabolites in urine of obese patients with craniopharyngioma.
  • Severe obesity is a major problem in patients suffering from craniopharyngioma (CP), a benign tumor located in pituitary and hypothalamic regions.
  • HVA and VMA results were compared with age-matched HVA and VMA in urine of patients proven to not have a catecholamine-secreting tumor.
  • The low HVA and VMA values suggest decreased sympathetic outflow contributing to reduced physical activity and severe obesity, especially in patients with a hypothalamic tumor.
  • [MeSH-major] Craniopharyngioma / urine. Obesity / urine. Sympathetic Nervous System / metabolism
  • [MeSH-minor] Adolescent. Adult. Dopamine / urine. Epinephrine / urine. Female. Homovanillic Acid / urine. Humans. Male. Norepinephrine / urine. Vanilmandelic Acid / urine

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Obesity.
  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. Norepinephrine .
  • Hazardous Substances Data Bank. EPINEPHRINE .
  • Hazardous Substances Data Bank. DOPAMINE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17515878.001).
  • [ISSN] 0031-3998
  • [Journal-full-title] Pediatric research
  • [ISO-abbreviation] Pediatr. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 55-10-7 / Vanilmandelic Acid; VTD58H1Z2X / Dopamine; X4W3ENH1CV / Norepinephrine; X77S6GMS36 / Homovanillic Acid; YKH834O4BH / Epinephrine
  •  go-up   go-down


27. Xu J, You C, Zhou L, Li Q, Zhou P, Chen N: The cell-cycle kinetics of craniopharyngioma and its clinical significance. J Neurooncol; 2010 May;98(1):71-6
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The cell-cycle kinetics of craniopharyngioma and its clinical significance.
  • Craniopharyngioma (CP) is a pathologically benign tumor with high incidence of recurrence and poor prognosis.
  • By use of FCM and terminal deoxynucleotide transferase-mediated dUTP nick end labeling (TUNEL) peroxidase, we compared DNA content, SPF, G2/M + S, necrosis and apoptosis in non-recurrent and recurrent tumor cells of CP from 63 cases including 32 adamantine epitheliomas (AEs) and 31 squamous papillary tumors (SPTs), and the ultrastructure of the CP cell was observed by transmission electron microscopy.
  • [MeSH-major] Cell Cycle / physiology. Craniopharyngioma / pathology. Craniopharyngioma / physiopathology. Pituitary Neoplasms / pathology. Pituitary Neoplasms / physiopathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Apoptosis / physiology. Child. Child, Preschool. Female. Flow Cytometry / methods. Follow-Up Studies. G2 Phase / physiology. Humans. In Situ Nick-End Labeling / methods. Male. Microscopy, Electron, Transmission / methods. Middle Aged. Retrospective Studies. S Phase / physiology. Young Adult

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19937088.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


28. Guo CJ, Wang YC, Zhou ZH, Zhu JX, Li ZM, Guo CL: [Curative effect of stereotactic 186Re endocavitary irradiation on cystic craniopharyngioma]. Zhonghua Zhong Liu Za Zhi; 2010 Jul;32(7):548-50
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Curative effect of stereotactic 186Re endocavitary irradiation on cystic craniopharyngioma].
  • OBJECTIVE: To evaluate the treatment results of stereotactic (186)Re intracavitary irradiation in the patients with craniopharyngioma.
  • The mean volume of the cystic portion of the tumor before irradiation was 8390 mm(3).
  • CONCLUSION: Stereotactic (186)Re endocavitary irradiation for the treatment of cystic craniopharyngioma is a safe and effective procedure.
  • [MeSH-major] Brachytherapy / methods. Craniopharyngioma / radiotherapy. Pituitary Neoplasms / radiotherapy. Radioisotopes / therapeutic use. Rhenium / therapeutic use
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Cysts / radiotherapy. Female. Follow-Up Studies. Humans. Male. Middle Aged. Stereotaxic Techniques. Treatment Outcome. Young Adult

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21029702.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Radioisotopes; 7440-15-5 / Rhenium
  •  go-up   go-down


29. Xu JG, You C, Cai BW, Jiang S, Sun H, Guo FY, Yang YB, Wu B: Microsurgical resection of craniopharyngioma of the third ventricle via an improved transventricular approach. Chin Med J (Engl); 2005 May 20;118(10):806-11
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Microsurgical resection of craniopharyngioma of the third ventricle via an improved transventricular approach.
  • BACKGROUND: Craniopharyngioma of the third ventricle is difficult to treat and its therapeutic regimens and operative approaches have been controversial.
  • This study was undertaken to probe indications for microsurgical resection of craniopharyngioma of the third ventricle via an improved transventricular approach, its surgical procedures and therapeutic effects, and prevention of postoperative complications.
  • METHODS: Fifty-one patients with craniopharyngioma of the third ventricle were treated from January 2000 to October 2004 by an improved transventricular approach for removing the tumor via the interventricular foramen, the intermedius of the septum pellucidum or choroid fissure.
  • CONCLUSIONS: Microsurgical resection of craniopharyngioma of the third ventricle by an improved transventricular approach has advantages of operative safety and efficacy, lower mortality and disability, and less complications.
  • [MeSH-major] Cerebral Ventricle Neoplasms / surgery. Craniopharyngioma / surgery. Microsurgery. Pituitary Neoplasms / surgery. Third Ventricle
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Female. Humans. Infant. Male. Middle Aged

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15989759.001).
  • [ISSN] 0366-6999
  • [Journal-full-title] Chinese medical journal
  • [ISO-abbreviation] Chin. Med. J.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  •  go-up   go-down


30. Balak N, Aras A, Isik N, Elmaci I: [Making the differential diagnosis between pituitary apoplexy and craniopharyngioma]. Neurochirurgie; 2009 Dec;55(6):600-2
Genetic Alliance. consumer health - Craniopharyngioma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Making the differential diagnosis between pituitary apoplexy and craniopharyngioma].
  • [Transliterated title] Difficulté du diagnostic différentiel entre l'apoplexie hypophysaire et le craniopharyngiome.
  • Craniopharyngioma may be difficult to distinguish from pituitary apoplexy.
  • In our patient, the tumor was confused with a craniopharyngioma because of the suprasellar extension of the tumor on magnetic resonance (MR) images and the hyperintensity in T1-weighted images, the young age of the patient, and the gradually progressive onset of the symptoms.
  • In conclusion, even without a known history of pituitary adenoma or an abrupt onset of the clinical symptoms, the diagnosis of pituitary apoplexy should be considered in a patient with a suprasellar mass hyperintensity in T1-weighted MR images, which may mimic craniopharyngioma.
  • [MeSH-major] Craniopharyngioma / diagnosis. Pituitary Apoplexy / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. Pituitary Gland / pathology. Sella Turcica / pathology. Young Adult

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19091358.001).
  • [ISSN] 1773-0619
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  •  go-up   go-down


31. Qi S, Peng J, Pan J, Lu Y, Fan J: Secondary abscess arising in a craniopharyngioma. J Clin Neurosci; 2009 Dec;16(12):1667-9
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Secondary abscess arising in a craniopharyngioma.
  • An abscess arising in a craniopharyngioma is rare, but has potentially high mortality and morbidity.
  • We report a patient with a pituitary abscess concomitant with a craniopharyngioma and discuss the pathophysiological mechanism.
  • We discuss the previous five reports and suggest that abscesses with craniopharyngioma remain challenging clinical entities.
  • [MeSH-major] Abscess / etiology. Craniopharyngioma / complications. Pituitary Neoplasms / complications
  • [MeSH-minor] Adult. Follow-Up Studies. Humans. Magnetic Resonance Imaging / methods. Male

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Abscess.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19766002.001).
  • [ISSN] 1532-2653
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
  •  go-up   go-down


32. Park YS, Ahn JY, Kim DS, Kim TS, Kim SH: Late development of craniopharyngioma following surgery for Rathke's cleft cyst. Clin Neuropathol; 2009 May-Jun;28(3):177-81
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Late development of craniopharyngioma following surgery for Rathke's cleft cyst.
  • OBJECTIVE: Rathke's cleft cyst (RCC) may transform to papillary type craniopharyngioma (CP) after squamous metaplasia: this is referred to as ciliated CP.
  • 34 months after the initial surgery, the patient revisited our hospital for a rapidly aggravating visual disturbance and underwent neuroendoscopic biopsy and tumor removal via a bifrontal craniotomy.
  • Histologically, the tumor was shown to be an adamantinomatous CP.
  • [MeSH-major] Central Nervous System Cysts / pathology. Craniopharyngioma / pathology. Neoplasms, Second Primary / pathology. Pituitary Neoplasms / pathology
  • [MeSH-minor] Adult. Humans. Magnetic Resonance Imaging. Male. Neurosurgical Procedures. beta Catenin / metabolism

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19537134.001).
  • [ISSN] 0722-5091
  • [Journal-full-title] Clinical neuropathology
  • [ISO-abbreviation] Clin. Neuropathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / beta Catenin
  •  go-up   go-down


33. Müller HL, Handwerker G, Gebhardt U, Faldum A, Emser A, Kolb R, Sörensen N: Melatonin treatment in obese patients with childhood craniopharyngioma and increased daytime sleepiness. Cancer Causes Control; 2006 May;17(4):583-9
Hazardous Substances Data Bank. MELATONIN .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Melatonin treatment in obese patients with childhood craniopharyngioma and increased daytime sleepiness.
  • Craniopharyngioma is a rare dysontogenetic benign tumor.
  • A self-assessment daytime sleepiness questionnaire (German version of the Epworth Sleepiness Scale [ESS]) was used to evaluate 79 patients with childhood craniopharyngioma.
  • Because hypothalamic lesions may explain daytime sleepiness in craniopharyngioma patients, salivary melatonin and cortisol concentrations were examined in severely obese (BMI>or=4SD) and non severely obese (BMI<4SD) craniopharyngioma patients (n=79), patients with hypothalamic pilocytic astrocytoma (n=19), and control subjects (n=30).
  • Using a general linear model procedure analyzing the influence of BMI and tumor diagnosis on diurnal salivary melatonin we found that morning salivary melatonin levels were related to BMI (F test: p-value=0.004) and tumor diagnosis (F-test: p-value=0.032).
  • Also for nighttime salivary melatonin levels significant relations with BMI (p-value in F-test: <0.001) and tumor diagnosis (p-value in F-test: 0.025) were detectable.
  • Melatonin concentrations in saliva of craniopharyngioma patients collected at nighttime or in the morning showed a negative correlation (Spearman's rho: -0.42; p=0.001; Spearman's rho: -0.31; p=0.020) with the patient's ESS score.
  • Severely obese craniopharyngioma patients and severely obese hypothalamic tumor patients had similar patterns of melatonin secretion.
  • As decreased nocturnal melatonin levels were associated with increased daytime sleepiness, BMI and hypothalamic tumor diagnosis, we initiated an experimental melatonin substitution in 10 adult obese patients (5f/5m) with childhood craniopharyngioma.
  • In all 10 patients with childhood craniopharyngioma the degree of daytime sleepiness significantly improved based on activity diaries, ESS, self assessment questionnaires and actimetry.
  • [MeSH-major] Craniopharyngioma / metabolism. Melatonin / secretion. Melatonin / therapeutic use. Obesity / metabolism. Pituitary Neoplasms / metabolism. Sleep Stages
  • [MeSH-minor] Adolescent. Adult. Astrocytoma / complications. Astrocytoma / metabolism. Child. Child, Preschool. Circadian Rhythm. Disorders of Excessive Somnolence / complications. Disorders of Excessive Somnolence / drug therapy. Female. Humans. Hydrocortisone / blood. Hypothalamic Neoplasms / metabolism. Male. Saliva / chemistry


34. Pettorini BL, Frassanito P, Caldarelli M, Tamburrini G, Massimi L, Di Rocco C: Molecular pathogenesis of craniopharyngioma: switching from a surgical approach to a biological one. Neurosurg Focus; 2010 Apr;28(4):E1
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Molecular pathogenesis of craniopharyngioma: switching from a surgical approach to a biological one.
  • Craniopharyngioma has long been considered a benign tumor because of its pathological aspect.
  • This primordial view of craniopharyngioma fit with the primitive treatment attempts based on blind resection of the tumor each time it recurred.
  • Nowadays, craniopharyngioma must be considered a complex molecular disease, and a detailed explanation of the mechanisms underlying its aggressive biological and clinical behavior, despite some benign pathological features, would be the first step toward defining the best management of craniopharyngioma.
  • Indeed, advances in the knowledge of the molecular mechanisms at the base of craniopharyngioma oncogenesis will lead to comprehension of the critical checkpoints involved in neoplastic transformation.
  • In this paper the authors reveal state-of-the-art comprehension of the molecular biology of craniopharyngioma and the consequent therapeutic implications.
  • [MeSH-major] Craniopharyngioma / therapy. Pituitary Neoplasms / therapy
  • [MeSH-minor] Adult. Child. Humans. Molecular Biology / methods. Neoplastic Processes

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20367353.001).
  • [ISSN] 1092-0684
  • [Journal-full-title] Neurosurgical focus
  • [ISO-abbreviation] Neurosurg Focus
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 52
  •  go-up   go-down


35. O'Gorman CS, Simoneau-Roy J, Pencharz P, MacFarlane J, MacLusky I, Narang I, Adeli K, Daneman D, Hamilton J: Sleep-disordered breathing is increased in obese adolescents with craniopharyngioma compared with obese controls. J Clin Endocrinol Metab; 2010 May;95(5):2211-8
MedlinePlus Health Information. consumer health - Sleep Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sleep-disordered breathing is increased in obese adolescents with craniopharyngioma compared with obese controls.
  • CONTEXT: Retrospective studies suggest that adolescents with craniopharyngioma and hypothalamic obesity have increased sleep-disordered breathing (SDB).
  • OBJECTIVES: The objectives of this study were to compare the prevalence of SDB in adolescents with craniopharyngioma-related obesity compared with body mass index (BMI)-matched controls and to explore possible relationships between SDB, insulin resistance, and adipocytokines.
  • DESIGN: This was a cross-sectional study of obese craniopharyngioma and obese control adolescents.
  • PATIENTS: Fifteen patients with craniopharyngioma-related obesity and 15 BMI-matched controls were recruited and tested.
  • RESULTS: Insulin sensitivity was lower in craniopharyngioma subjects compared with control subjects (0.96 +/- 0.34 vs. 1.67 +/- 0.7, P = 0.01).
  • Sleep-onset latency (19.3 +/- 27.8 vs. 31.9 +/- 23.4, P = 0.03) and oxygen saturations (rapid eye movement sleep: 89.0 +/- 5.1 vs. 94.2 +/- 2.3, P < 0.001; non-rapid eye movement sleep: 88.4 +/- 5.6 vs. 94.3 +/- 1.5, P < 0.001) were lower in craniopharyngioma.
  • Obstructive apnea-hypopnea index (OAHI) (7.5 +/- 9.0 vs. 1.5 +/- 1.5, P = 0.03) was higher in craniopharyngioma.
  • Respiratory distress index and OAHI correlated negatively with adiponectin concentrations (r = -0.61, P = 0.03, r = -0.71, P = 0.006, respectively) in craniopharyngioma.
  • On multiple regression, TNF-alpha and craniopharyngioma were independent positive predictors of sleep-onset latency and adiponectin and craniopharyngioma were significant predictors (negative and positive, respectively) of OAHI.
  • CONCLUSIONS: SDB is increased in adolescents with craniopharyngioma-related obesity compared with BMI-matched controls.
  • Routine polysomnography should be considered in obese patients with craniopharyngioma and appropriate treatment initiated.
  • [MeSH-major] Craniopharyngioma / complications. Obesity / complications. Pituitary Neoplasms / complications. Respiration Disorders / physiopathology. Sleep Wake Disorders / physiopathology
  • [MeSH-minor] Adiponectin / blood. Adolescent. Body Mass Index. Body Size. Child. Female. Humans. Male. Young Adult

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Obesity.
  • MedlinePlus Health Information. consumer health - Obesity in Children.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20332250.001).
  • [ISSN] 1945-7197
  • [Journal-full-title] The Journal of clinical endocrinology and metabolism
  • [ISO-abbreviation] J. Clin. Endocrinol. Metab.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Adiponectin
  •  go-up   go-down


36. Joó JG, Rigó J Jr, Sápi Z, Timár B: Foetal craniopharyngioma diagnosed by prenatal ultrasonography and confirmed by histopathological examination. Prenat Diagn; 2009 Feb;29(2):160-3
MedlinePlus Health Information. consumer health - Prenatal Testing.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Foetal craniopharyngioma diagnosed by prenatal ultrasonography and confirmed by histopathological examination.
  • BACKGROUND: Craniopharyngioma is an intracranial tumour, which usually develops in children and young adults and rarely occurs in intrauterine life.
  • In relation to the current case report, we aimed at surveying the available information on prenatal craniopharyngioma.
  • [MeSH-major] Craniopharyngioma / pathology. Craniopharyngioma / ultrasonography. Pituitary Neoplasms / pathology. Pituitary Neoplasms / ultrasonography. Prenatal Diagnosis / methods
  • [MeSH-minor] Abortion, Induced. Adult. Fatal Outcome. Female. Fetus. Histocytochemistry. Humans. Infant, Newborn. Male. Pregnancy

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright (c) 2009 John Wiley & Sons, Ltd.
  • (PMID = 19180629.001).
  • [ISSN] 0197-3851
  • [Journal-full-title] Prenatal diagnosis
  • [ISO-abbreviation] Prenat. Diagn.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  •  go-up   go-down


37. Massengale J, Tafti BA, Large L, Skirboll S: Reversal of preoperative catatonic state by surgical resection of an adult-onset craniopharyngioma: case report and review of the literature. Cogn Behav Neurol; 2009 Mar;22(1):67-71
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Reversal of preoperative catatonic state by surgical resection of an adult-onset craniopharyngioma: case report and review of the literature.
  • OBJECTIVE: To describe a case of a rare adult-onset craniopharyngioma presenting as rapidly progressive catatonia that was reversed after surgical resection of the tumor.
  • CONCLUSIONS: The search for an etiology of a profound catatonic state should include the probability of a suprasellar/hypothalamic lesion, which in this case was owing to the rare finding of an imaging-documented adult-onset craniopharyngioma.
  • [MeSH-major] Catatonia / therapy. Craniopharyngioma / complications. Craniopharyngioma / surgery. Neurosurgical Procedures. Pituitary Neoplasms / complications. Pituitary Neoplasms / surgery
  • [MeSH-minor] Brain / pathology. Hormones / blood. Humans. Hypnotics and Sedatives / therapeutic use. Lorazepam / therapeutic use. Male. Middle Aged. Psychotic Disorders / complications. Psychotic Disorders / psychology

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19372773.001).
  • [ISSN] 1543-3641
  • [Journal-full-title] Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology
  • [ISO-abbreviation] Cogn Behav Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Hormones; 0 / Hypnotics and Sedatives; O26FZP769L / Lorazepam
  •  go-up   go-down


38. Choi SH, Kwon BJ, Na DG, Kim JH, Han MH, Chang KH: Pituitary adenoma, craniopharyngioma, and Rathke cleft cyst involving both intrasellar and suprasellar regions: differentiation using MRI. Clin Radiol; 2007 May;62(5):453-62
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pituitary adenoma, craniopharyngioma, and Rathke cleft cyst involving both intrasellar and suprasellar regions: differentiation using MRI.
  • AIMS: To determine the differential magnetic resonance imaging (MRI) features of pituitary adenoma, craniopharyngioma, and Rathke cleft cyst involving both intrasellar and suprasellar regions.
  • MATERIALS AND METHODS: The MRI images of 64 patients with pituitary adenoma (n=38), craniopharyngioma (n=13), or Rathke cleft cyst (n=13) were retrospectively reviewed by three neuroradiologists.
  • A superiorly lobulated shape, third ventricle compression by superior tumour extension, mixed solid and cystic characteristics, and reticular enhancement of the solid portion were more common in craniopharyngiomas (p<0.017).
  • Finally, an ovoid shape, a small tumour volume, cystic characteristics, and no or thin cyst wall enhancement were more common in Rathke cleft cysts (p<0.017).
  • The flowchart yielded diagnostic accuracies as follows: 92.1% in pituitary adenoma; 92.3% in craniopharyngioma; 92.3% in Rathke cleft cyst; and 92.2% overall.
  • [MeSH-major] Adenoma / pathology. Central Nervous System Cysts / pathology. Craniopharyngioma / pathology. Magnetic Resonance Imaging / methods. Pituitary Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Radiology Information Systems. Retrospective Studies

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - MRI Scans.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17398271.001).
  • [ISSN] 0009-9260
  • [Journal-full-title] Clinical radiology
  • [ISO-abbreviation] Clin Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  •  go-up   go-down


39. Van Gompel JJ, Nippoldt TB, Higgins DM, Meyer FB: Magnetic resonance imaging-graded hypothalamic compression in surgically treated adult craniopharyngiomas determining postoperative obesity. Neurosurg Focus; 2010 Apr;28(4):E3
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Magnetic resonance imaging-graded hypothalamic compression in surgically treated adult craniopharyngiomas determining postoperative obesity.
  • OBJECT: Obesity as a consequence of management of pediatric craniopharyngioma is a well-described phenomenon related to the degree of hypothalamic involvement.
  • However, weight change and obesity have not been analyzed in adult patients.
  • Therefore, the purpose of this study was 1) to evaluate the pattern of postoperative weight gain related to preoperative body mass index (BMI), 2) determine if postoperative weight gain is an issue in adult patients, and 3) develop an objective MR imaging grading system to predict risk of postoperative weight gain and obesity in adults treated for craniopharyngioma.
  • METHODS: The authors retrospectively screened 296 patients with known craniopharyngioma for the following inclusion criteria: pathologically confirmed craniopharyngioma, index surgery at the authors' institution, and operative weight and height recorded with at least 3 months of follow-up including body weight measurement.
  • Cases of craniopharyngiomas were compared with age- and sex-matched controls (pituitary adenoma patients) to evaluate the pattern and significance of perioperative weight changes.
  • Comparing craniopharyngioma patients (cases) to age- and sex-matched controls, the preoperative BMIs were similar (p = 0.93) between cases (mean 28.9 [95% CI 30.9-26.9]) and controls (mean 29.3 [95% CI 31.9-26.7]).
  • CONCLUSIONS: Postoperative weight gain in adult patients undergoing surgery for craniopharyngioma is a significant problem and correlates with hypothalamic involvement, as it does in pediatric patients.
  • [MeSH-major] Craniopharyngioma / surgery. Magnetic Resonance Imaging / statistics & numerical data. Obesity / diagnosis. Pituitary Neoplasms / surgery. Postoperative Complications / diagnosis
  • [MeSH-minor] Adolescent. Adult. Age Factors. Body Mass Index. Female. Follow-Up Studies. Humans. Hypophysectomy / methods. Hypothalamus / pathology. Hypothalamus / surgery. Male. Preoperative Care. Retrospective Studies. Risk Factors. Weight Gain

  • Genetic Alliance. consumer health - Obesity.
  • MedlinePlus Health Information. consumer health - After Surgery.
  • MedlinePlus Health Information. consumer health - MRI Scans.
  • MedlinePlus Health Information. consumer health - Obesity.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20367360.001).
  • [ISSN] 1092-0684
  • [Journal-full-title] Neurosurgical focus
  • [ISO-abbreviation] Neurosurg Focus
  • [Language] eng
  • [Grant] United States / NCRR NIH HHS / RR / UL1 RR024150
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  •  go-up   go-down


40. Stienen MN, Cadosch D, Bilz S, Hildebrandt G, Gautschi OP: [Craniopharyngioma--a "geographical malignant" tumour]. Praxis (Bern 1994); 2010 Jul 28;99(15):911-21
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Craniopharyngioma--a "geographical malignant" tumour].
  • [Transliterated title] Das Kraniopharyngeom--ein "geographisch maligner" Tumor.
  • The craniopharyngioma is a rare dysontogenetic tumour that originates from either scattered cells of the craniopharyngeal duct or from metaplastically mutated anterior pituitary parenchyma cells.
  • Despite being classified as a WHO-Class-I tumour, the histologically benign craniopharyngioma may display an aggressive behaviour.
  • [MeSH-major] Craniopharyngioma / diagnosis. Pituitary Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Adult. Child. Combined Modality Therapy. Cranial Irradiation. Diagnosis, Differential. Female. Humans. Hypophysectomy. Magnetic Resonance Imaging. Male. Pituitary Gland / pathology. Practice Guidelines as Topic. Prognosis. Radiosurgery. Tomography, X-Ray Computed

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20715005.001).
  • [ISSN] 1661-8157
  • [Journal-full-title] Praxis
  • [ISO-abbreviation] Praxis (Bern 1994)
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 54
  •  go-up   go-down


41. Chakrabarti I, Amar AP, Couldwell W, Weiss MH: Long-term neurological, visual, and endocrine outcomes following transnasal resection of craniopharyngioma. J Neurosurg; 2005 Apr;102(4):650-7
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term neurological, visual, and endocrine outcomes following transnasal resection of craniopharyngioma.
  • OBJECT: The authors report on a cohort of patients with craniopharyngioma treated principally through transnasal (TN) resection and followed up for a minimum of 5 years.
  • More specifically, they evaluate the role of the TN approach in the management of craniopharyngioma.
  • METHODS: Between 1984 and 1994, 68 patients underwent TN resection of craniopharyngiomas at the University of Southern California.
  • The tumor was at least partially cystic in 88% of cases.
  • During the same period, 18 patients underwent transcranial (TC) resection of purely suprasellar craniopharyngiomas.
  • CONCLUSIONS: Use of the TN approach can render good outcomes in properly selected patients with craniopharyngioma, particularly when the tumor is cystic.
  • [MeSH-major] Craniopharyngioma / surgery. Neoplasm Recurrence, Local. Pituitary Neoplasms / surgery. Postoperative Complications
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Endocrine System Diseases / etiology. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Nasal Cavity / surgery. Subdural Effusion. Treatment Outcome


42. Floyd JR, Cmelak A, Russell P, Weaver KD: Endoscopic, image-guided, transnasal instillation of (32)P for recurrent infrachiasmatic cystic craniopharyngioma. Minim Invasive Neurosurg; 2009 Jun;52(3):137-40
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic, image-guided, transnasal instillation of (32)P for recurrent infrachiasmatic cystic craniopharyngioma.
  • INTRODUCTION: The neurovascular and anatomic relationships surrounding craniopharyngiomas, and their tending to recur despite any method of primary treatment, has characterized this tumor as an exigent and frustrating clinical entity.
  • CASE REPORT: We present a case where the patient had previously experienced a transsphenoidal resection followed by a pterional, microsurgical resection of her craniopharyngioma at an outside hospital.
  • CONCLUSION: While intracystic adionucleotide therapies have been utilized for primary and secondary treatment of craniopharyngioma, to our knowledge, this is the first report of the delivery of this therapy by an endoscopic transsphenoidal route.
  • [MeSH-major] Craniopharyngioma / radiotherapy. Craniopharyngioma / surgery. Endoscopy / methods. Neoplasm Recurrence, Local / radiotherapy. Neoplasm Recurrence, Local / surgery. Pituitary Neoplasms / radiotherapy. Pituitary Neoplasms / surgery
  • [MeSH-minor] Adult. Combined Modality Therapy. Female. Humans. Minimally Invasive Surgical Procedures / methods. Neurosurgical Procedures / methods. Phosphorus Radioisotopes. Radiotherapy. Treatment Outcome

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Endoscopy.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright Georg Thieme Verlag KG Stuttgart. New York.
  • (PMID = 19650017.001).
  • [ISSN] 1439-2291
  • [Journal-full-title] Minimally invasive neurosurgery : MIN
  • [ISO-abbreviation] Minim Invasive Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Phosphorus Radioisotopes
  •  go-up   go-down


43. Crowley RK, Hamnvik OP, O'Sullivan EP, Behan LA, Smith D, Agha A, Thompson CJ: Morbidity and mortality in patients with craniopharyngioma after surgery. Clin Endocrinol (Oxf); 2010 Oct;73(4):516-21
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Morbidity and mortality in patients with craniopharyngioma after surgery.
  • OBJECTIVE: Craniopharyngioma (CP) is a benign tumour of the suprasellar region that is associated with increased morbidity and mortality in comparison with other causes of hypopituitarism.
  • [MeSH-major] Craniopharyngioma / mortality. Pituitary Neoplasms / mortality
  • [MeSH-minor] Adolescent. Adrenocorticotropic Hormone / deficiency. Adult. Body Mass Index. Child. Child, Preschool. Female. Human Growth Hormone / deficiency. Humans. Infant. Male. Middle Aged. Morbidity. Retrospective Studies. Sex Characteristics

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • Hazardous Substances Data Bank. Corticotropin .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] © 2010 Blackwell Publishing Ltd.
  • (PMID = 20550527.001).
  • [ISSN] 1365-2265
  • [Journal-full-title] Clinical endocrinology
  • [ISO-abbreviation] Clin. Endocrinol. (Oxf)
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 12629-01-5 / Human Growth Hormone; 9002-60-2 / Adrenocorticotropic Hormone
  •  go-up   go-down


44. Karavitaki N, Warner JT, Marland A, Shine B, Ryan F, Arnold J, Turner HE, Wass JA: GH replacement does not increase the risk of recurrence in patients with craniopharyngioma. Clin Endocrinol (Oxf); 2006 May;64(5):556-60
MedlinePlus Health Information. consumer health - Hormone Replacement Therapy.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] GH replacement does not increase the risk of recurrence in patients with craniopharyngioma.
  • BACKGROUND: A significant number of patients with craniopharyngioma are GH deficient.
  • OBJECTIVE: To assess the effect of GH replacement upon recurrence in patients with craniopharyngioma.
  • PATIENTS AND METHODS: All the patients with craniopharyngioma followed-up at the Departments of Endocrinology or Paediatrics in Oxford and treated or not with GH were studied retrospectively.
  • The remaining 32 (22 males/10 females) received GH for a mean period of 6.3 +/- 4.6 years (median 5.1, range 0.8-22); 21 started during childhood (13 of them continued after the achievement of final height with an adult dose) and 11 during adult life.
  • None of the nine patients with insufficient imaging data for inclusion in the statistical analyses [5 men/4 women, 3 treated with GH during childhood/6 during adult life, mean duration of GH therapy 2.9 +/- 2.4 years (median 1.8, range 0.4-7)] showed clinical features suggestive of recurrence during the period of GH replacement.
  • CONCLUSION Based on the data of the craniopharyngiomas database in Oxford, there is no evidence that GH replacement is associated with an increased risk of tumour recurrence.
  • [MeSH-major] Brain Neoplasms / pathology. Craniopharyngioma / pathology. Growth Hormone / therapeutic use. Hormone Replacement Therapy. Neoplasm Recurrence, Local / pathology
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Female. Follow-Up Studies. Humans. Infant. Male. Middle Aged. Proportional Hazards Models. Retrospective Studies. Risk Factors

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • MedlinePlus Health Information. consumer health - Childhood Brain Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16649976.001).
  • [ISSN] 0300-0664
  • [Journal-full-title] Clinical endocrinology
  • [ISO-abbreviation] Clin. Endocrinol. (Oxf)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 9002-72-6 / Growth Hormone
  •  go-up   go-down


45. Sands SA, Milner JS, Goldberg J, Mukhi V, Moliterno JA, Maxfield C, Wisoff JH: Quality of life and behavioral follow-up study of pediatric survivors of craniopharyngioma. J Neurosurg; 2005 Oct;103(4 Suppl):302-11
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Quality of life and behavioral follow-up study of pediatric survivors of craniopharyngioma.
  • OBJECT: The authors set out to evaluate the quality of life (QOL), social-emotional functioning, and behavioral functioning of children treated surgically for craniopharyngiomas.
  • After a mean follow-up period of 6.8 +/- 3.5 years, these 29 patients were administered either the 36-item Short Form Health Survey version 2 or the Child Health Questionnaire-Parent Form to assess QOL, as well as the Achenbach Child Behavior Checklist or Young Adult Checklist to measure social-emotional and behavioral functioning.
  • Further analyses indicated that retrochiasmatic tumor location, recurrence, and additional surgery were associated with poorer outcomes.
  • In contrast, hydrocephalus, tumor size, and sex were not prognostic variables, and patients significantly improved as post-operative time increased.
  • CONCLUSIONS: Attention toward late effects arising after the treatment of pediatric craniopharyngioma, including decreased postoperative physical health and behavioral functioning, is warranted.
  • Future approaches to treatment should consider the documented effects of either gross-total resection or limited surgery followed by cranial irradiation on QOL, with specific evaluation for those with retrochiasmatic tumors, a recurrent tumor, or the need for additional surgery.
  • [MeSH-major] Child Behavior. Craniopharyngioma / surgery. Pituitary Neoplasms / surgery. Quality of Life. Social Behavior
  • [MeSH-minor] Adolescent. Adult. Child. Female. Follow-Up Studies. Humans. Male. Postoperative Complications

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] J Neurosurg. 2005 Oct;103(4 Suppl):297-8; discussion 298 [16270679.001]
  • (PMID = 16270681.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


46. Romani R, Niemelä M, Celik O, Isarakul P, Paetau A, Hernesniemi J: Ectopic recurrence of craniopharyngioma along the surgical route: case report and literature review. Acta Neurochir (Wien); 2010 Feb;152(2):297-302; discussion 302
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ectopic recurrence of craniopharyngioma along the surgical route: case report and literature review.
  • We present a 22-year-old woman with an ectopic recurrence of a craniopharyngioma.
  • The patient presented first with a visual field deficit, and a craniopharyngioma was removed via an interhemispheric transcallosal approach.
  • However, at 4 years, MRI showed the presence of a small tumor in the right medial frontal lobe attached to the falx and along the previous surgical route.
  • [MeSH-major] Brain Neoplasms / secondary. Craniopharyngioma / secondary. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Neoplasm Seeding. Pituitary Neoplasms / pathology
  • [MeSH-minor] Choristoma / pathology. Choristoma / physiopathology. Choristoma / surgery. Corpus Callosum / anatomy & histology. Corpus Callosum / surgery. Dura Mater / pathology. Dura Mater / surgery. Female. Frontal Lobe / pathology. Frontal Lobe / surgery. Humans. Magnetic Resonance Imaging. Neoplasm Metastasis / pathology. Neoplasm Metastasis / therapy. Neurosurgical Procedures. Pituitary Gland / pathology. Pituitary Gland / surgery. Postoperative Complications / pathology. Postoperative Complications / surgery. Sella Turcica / pathology. Sella Turcica / surgery. Treatment Outcome. Young Adult

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19499168.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Austria
  • [Number-of-references] 29
  •  go-up   go-down


47. Bianco Ade M, Madeira LV, Rosemberg S, Shibata MK: Cortical seeding of a craniopharyngioma after craniotomy: Case report. Surg Neurol; 2006 Oct;66(4):437-40; discussion 440
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cortical seeding of a craniopharyngioma after craniotomy: Case report.
  • BACKGROUND: Cortical seeding of a craniopharyngioma has been rarely reported.
  • METHODS: A 27-year-old woman presented earlier with a suprasellar craniopharyngioma.
  • A left frontotemporal craniotomy was done with subtotal resection of the tumor because it was strongly adhered to the optic chiasm.
  • Histopathology confirmed the diagnosis of craniopharyngioma.
  • Magnetic resonance imaging revealed a contrast-enhancing tumor with cystic and solid components on the left temporal lobe cortex.
  • The primary tumor bed was intact.
  • The patient was reoperated, and the temporal lobe tumor was totally removed.
  • Histologic studies showed an adamantinomatous craniopharyngioma.
  • CONCLUSIONS: Although craniopharyngiomas exhibit a benign histopathologic pattern, a total resection combined with careful inspection and irrigation of the surgical field is the optimal treatment for preventing local and ectopic recurrences.
  • [MeSH-major] Brain Neoplasms / secondary. Craniopharyngioma / secondary. Neoplasm Seeding. Pituitary Neoplasms / pathology. Temporal Lobe / pathology
  • [MeSH-minor] Adult. Craniotomy. Female. Humans. Magnetic Resonance Imaging. Neoplasm Recurrence, Local. Neurosurgical Procedures / methods. Neurosurgical Procedures / standards. Optic Chiasm / pathology. Optic Chiasm / physiopathology. Seizures / etiology. Seizures / physiopathology. Treatment Outcome. Vision, Low / etiology. Vision, Low / physiopathology

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17015135.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


48. Müller HL, Bruhnken G, Emser A, Faldum A, Etavard-Gorris N, Gebhardt U, Kolb R, Sörensen N: Longitudinal study on quality of life in 102 survivors of childhood craniopharyngioma. Childs Nerv Syst; 2005 Nov;21(11):975-80
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Longitudinal study on quality of life in 102 survivors of childhood craniopharyngioma.
  • OBJECTS: We longitudinally analysed functional capacity and quality of life (QoL) in 102 patients with a childhood craniopharyngioma during follow-up.
  • [MeSH-major] Craniopharyngioma / psychology. Hypophysectomy / psychology. Pituitary Neoplasms / psychology. Quality of Life / psychology. Survivors / psychology
  • [MeSH-minor] Activities of Daily Living / classification. Activities of Daily Living / psychology. Adolescent. Adult. Body Mass Index. Child. Child, Preschool. Combined Modality Therapy. Disease Progression. Female. Follow-Up Studies. Humans. Hypothalamus / pathology. Infant. Longitudinal Studies. Male. Neoplasm Invasiveness. Neoplasm Recurrence, Local / psychology. Obesity / psychology. Pituitary Irradiation. Postoperative Complications / psychology. Psychometrics / statistics & numerical data. Radiotherapy, Adjuvant. Reproducibility of Results. Self-Assessment. Sickness Impact Profile

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16075216.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  •  go-up   go-down


49. Wang L, Zhao SF, Zhang W, Zhang MZ: Treatment of alternated water-electrolyte balance and endocrine status after removal of craniopharyngioma in adults. Chin Med J (Engl); 2006 Aug 20;119(16):1348-52
MedlinePlus Health Information. consumer health - Fluid and Electrolyte Balance.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Treatment of alternated water-electrolyte balance and endocrine status after removal of craniopharyngioma in adults.
  • BACKGROUND: Water-electrolyte disturbance and endocrine alterations are common complications of adult patients with craniopharygioma in the postoperative period and may affect their recovery and prognosis.
  • Appropriate remedy based upon the status of water-electrolyte balance and the endocrine system is essential to good therapeutic results of adult patients with craniopharyngioma.
  • METHODS: The alterations in water-electrolyte balance (117 patients) and endocrine status (42) of adult patients with craniopharyngioma after surgery were analyzed retrospectively.
  • RESULTS: Most patients with craniopharyngioma experienced postoperative water-electrolyte disturbances and hypotonic dehydration.
  • CONCLUSION: It is critical to deal with dehydration and endocrine disorders for a sound outcome of craniopharyngioma surgery.
  • [MeSH-major] Craniopharyngioma / surgery. Endocrine Glands / pathology. Water-Electrolyte Imbalance / physiopathology
  • [MeSH-minor] Adolescent. Adult. Female. Humans. Male. Middle Aged. Neurosurgical Procedures / methods. Postoperative Complications / physiopathology. Retrospective Studies. Treatment Outcome

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16934180.001).
  • [ISSN] 0366-6999
  • [Journal-full-title] Chinese medical journal
  • [ISO-abbreviation] Chin. Med. J.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  •  go-up   go-down


50. Müller HL, Gebhardt U, Pohl F, Flentje M, Emser A, Warmuth-Metz M, Kolb R, Calaminus G, Sörensen N: Relapse pattern after complete resection and early progression after incomplete resection of childhood craniopharyngioma. Klin Padiatr; 2006 Nov-Dec;218(6):315-20
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Relapse pattern after complete resection and early progression after incomplete resection of childhood craniopharyngioma.
  • In HIT Endo data on therapy and prognosis of 306 patients with childhood craniopharyngioma (CP) were analyzed.
  • [MeSH-major] Craniopharyngioma / surgery. Neoplasm Recurrence, Local. Pituitary Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Age Factors. Child. Child, Preschool. Disease Progression. Follow-Up Studies. Humans. Infant. Infant, Newborn. Magnetic Resonance Imaging. Multicenter Studies as Topic. Neoplasm, Residual. Prospective Studies. Radiotherapy Dosage. Reoperation. Surveys and Questionnaires. Survival Analysis. Time Factors

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17080333.001).
  • [ISSN] 0300-8630
  • [Journal-full-title] Klinische Pädiatrie
  • [ISO-abbreviation] Klin Padiatr
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  •  go-up   go-down


51. Yamada S, Fukuhara N, Oyama K, Takeshita A, Takeuchi Y, Ito J, Inoshita N: Surgical outcome in 90 patients with craniopharyngioma: an evaluation of transsphenoidal surgery. World Neurosurg; 2010 Aug-Sep;74(2-3):320-30
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical outcome in 90 patients with craniopharyngioma: an evaluation of transsphenoidal surgery.
  • OBJECTIVE: To analyze surgical outcomes in 90 patients with craniopharyngioma treated by standard transsphenoidal surgery (TSS) or extended transsphenoidal surgery (eTSS).
  • METHODS: From 1990-2008, 90 patients (64 adults and 26 children) underwent TSS for craniopharyngioma (34 subdiaphragmatic and 56 supradiaphragmatic).
  • RESULTS: Total tumor removal was achieved in 70 (77.8%) patients, subtotal removal was achieved in 17 (18.9%), and partial removal was achieved in 3 (3.3%).
  • Tumor recurrence was observed in seven (7.8%) patients during a mean follow-up period of 4.6 years.
  • CONCLUSIONS: Most craniopharyngiomas including the supradiaphragmatic type can be removed safely by TSS with a good outcome, although endocrine function frequently worsens after surgery.
  • [MeSH-major] Craniopharyngioma / surgery. Neurosurgical Procedures / methods. Pituitary Neoplasms / surgery. Sphenoid Bone / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Female. Follow-Up Studies. Hormones / blood. Humans. Image Interpretation, Computer-Assisted. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Recurrence, Local. Pituitary Gland / pathology. Postoperative Complications / mortality. Postoperative Complications / pathology. Tomography, X-Ray Computed. Treatment Outcome. Vision Disorders / etiology. Vision Tests. Vision, Ocular. Young Adult

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • [CommentIn] World Neurosurg. 2010 Aug-Sep;74(2-3):256-8 [21492550.001]
  • [CommentIn] World Neurosurg. 2010 Aug-Sep;74(2-3):254-5 [21492549.001]
  • (PMID = 21492566.001).
  • [ISSN] 1878-8769
  • [Journal-full-title] World neurosurgery
  • [ISO-abbreviation] World Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Hormones
  •  go-up   go-down


52. Daneshbod Y, Monabati A, Kumar PV, Taghipoor M, Bedayat GR: Intraoperative cytologic crush preparation findings in craniopharyngioma: a study of 72 cases. Acta Cytol; 2005 Jan-Feb;49(1):7-10
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intraoperative cytologic crush preparation findings in craniopharyngioma: a study of 72 cases.
  • OBJECTIVE: To describe the intraoperative crush preparation and the cytologic features of craniopharyngioma and the differential diagnosis.
  • STUDY DESIGN: Twelve cases of craniopharyngioma were diagnosed by crush preparation cytology in the Department of Pathology, Shiraz Medical School, and formed the basis of this study.
  • The smears were diagnosed as suggestive of craniopharyngioma.
  • CONCLUSION: Intraoperative cytologic crush preparation findings are helpful in the diagnosis of craniopharyngioma, when combined with clinical information.
  • Crush preparation cytology is important in the diagnosis of central nervous system tumors.
  • [MeSH-major] Craniopharyngioma / pathology. Pituitary Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Child. Cytodiagnosis. Diagnosis, Differential. Female. Humans. Male. Staining and Labeling / methods

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15717747.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


53. Brown JL, Burton DW, Deftos LJ, Smith AA, Pincus DW, Haller MJ: Congenital craniopharyngioma and hypercalcemia induced by parathyroid hormone-related protein. Endocr Pract; 2007 Jan-Feb;13(1):67-71
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Congenital craniopharyngioma and hypercalcemia induced by parathyroid hormone-related protein.
  • OBJECTIVE: To report a case of congenital craniopharyngioma and parathyroid hormone-related protein (PTHrP)-associated humoral hypercalcemia.
  • METHODS: Details of this unusual case are reviewed, from detection of fetal hydrocephalus and a brain tumor, through cesarean delivery at 36 weeks of gestation, to subsequent laboratory studies, management, and confirmation of the diagnosis.
  • RESULTS: Although PTHrP has been well documented as a cause of humoral hypercalcemia of malignancy (HHM) in adult patients with cancer, HHM is uncommon in children.
  • To the best of our knowledge, we report the first case of a neonate with congenital craniopharyngioma and refractory hypercalcemia (peak ionized calcium level of 1.92 mmol/L; normal, 1.05 to 1.3) attributed to an elevated PTHrP value of 8.6 pmol/L (normal, less than 4.7).
  • CONCLUSION: The diagnosis of craniopharyngioma was confirmed at autopsy, and immunohistochemical studies substantiated that the craniopharyngioma produced PTHrP.
  • [MeSH-major] Craniopharyngioma / congenital. Craniopharyngioma / metabolism. Hypercalcemia / etiology. Parathyroid Hormone-Related Protein / metabolism. Pituitary Neoplasms / congenital. Pituitary Neoplasms / metabolism
  • [MeSH-minor] Adult. Calcium / blood. Fatal Outcome. Female. Humans. Infant, Newborn. Magnetic Resonance Imaging. Pregnancy. Prenatal Diagnosis

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17360305.001).
  • [ISSN] 1934-2403
  • [Journal-full-title] Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
  • [ISO-abbreviation] Endocr Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Parathyroid Hormone-Related Protein; SY7Q814VUP / Calcium
  •  go-up   go-down


54. Kyrgiannis K, Mourgela S, Karamanakos PN, Liaropoulos K, Papadakis N: Optimal treatment of a recurrent giant craniopharyngioma: lessons from a case. J BUON; 2008 Oct-Dec;13(4):593-6
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Optimal treatment of a recurrent giant craniopharyngioma: lessons from a case.
  • A case of a 33-year-old man presented with symptoms of dramatic deterioration of the level of consciousness because of a recurrence of a previously aspirated and irradiated craniopharyngioma is described.
  • The tumor had grown enormously in dimensions and was extending in the region of hypothalamus, third ventricle and brain stem, with signs of local compression and obstructive hydrocephalus.
  • We conclude that in expert hands, microsurgery aiming at total removal should be the therapeutic option for the treatment of recurrent as well as primary craniopharyngiomas.
  • [MeSH-major] Craniopharyngioma / surgery. Pituitary Neoplasms / surgery
  • [MeSH-minor] Adult. Humans. Magnetic Resonance Imaging. Male. Microsurgery. Neoplasm Recurrence, Local. Tomography, X-Ray Computed

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19145689.001).
  • [ISSN] 1107-0625
  • [Journal-full-title] Journal of B.U.ON. : official journal of the Balkan Union of Oncology
  • [ISO-abbreviation] J BUON
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  •  go-up   go-down


55. Tena-Suck ML, Moreno-Reyes I, Rembao D, Vega R, Moreno-Jiménez S, Castillejos-López Mde J, Fernández-Plata R, Martínez-Briseño D, Salinas-Lara C: [Clinical pathological study of craniopharyngioma. Fifteen years at the National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez"]. Gac Med Mex; 2009 Sep-Oct;145(5):361-8
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clinical pathological study of craniopharyngioma. Fifteen years at the National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez"].
  • [Transliterated title] Craneofaringioma, estudio clínico-patológico. Quince años del Instituto Nacional de Neurología y Neurocirugía "Manuel Velasco Suárez".
  • BACKGROUND: Craniopharyngioma is a sellar region benign cyst It's frequency ranges from 1.2% to 4.6% of all brain tumors.
  • OBJECTIVE: To carry out a clinical pathological correlation of craniopharyngioma among adults and describe the tumor's biological characteristics.
  • METHODS: We included 115 craniopharyngiomas; 100 were adamantimomatous and 15 were papillary type.
  • Follow-up was longer among females than males and in suprasellar tumor location, papillary type, external epithelium cysts and laxo stellate reticulum.
  • CONCLUSIONS: However a good prognostic factor in craniopharyngiomas was observed in older female patients with complete exeresis, small tumors, external epithelium cysts, edematous stroma, inflammation, and absence of atypical cell and mitosis.
  • [MeSH-major] Craniopharyngioma / pathology. Pituitary Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Retrospective Studies. Young Adult

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20073441.001).
  • [ISSN] 0016-3813
  • [Journal-full-title] Gaceta médica de México
  • [ISO-abbreviation] Gac Med Mex
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Mexico
  •  go-up   go-down


56. Müller HL, Gebhardt U, Etavard-Gorris N, Kolb R, Warmuth-Metz M, Sörensen N: Current strategies in diagnostics and endocrine treatment of patients with childhood craniopharyngioma during follow-up--recommendations in KRANIOPHARYNGEOM 2000. Onkologie; 2005 Mar;28(3):150-6
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Current strategies in diagnostics and endocrine treatment of patients with childhood craniopharyngioma during follow-up--recommendations in KRANIOPHARYNGEOM 2000.
  • Craniopharyngiomas are rare dysontogenetic malformations.
  • As the survival rate after craniopharyngioma diagnosed during childhood and adolescence is high, prognosis and quality of life (QoL) in survivors mainly depend on adverse late effects such as hypopituitarism and obesity.
  • In order to evaluate and standardize diagnostic and therapeutical strategies in childhood craniopharyngioma the prospective multicenter surveillance study KRANIOPHARYNGEOM 2000 was initiated for patients diagnosed with craniopharyngioma during childhood and adolescence.
  • We are reporting on current strategies for laboratory diagnostics and endocrine substitution in patients with childhood craniopharyngioma recruited in KRANIOPHARYNGEOM 2000.
  • [MeSH-major] Craniopharyngioma / diagnosis. Craniopharyngioma / therapy. Diabetes Insipidus, Neurogenic / diagnosis. Diabetes Insipidus, Neurogenic / therapy. Pituitary Neoplasms / diagnosis. Pituitary Neoplasms / therapy
  • [MeSH-minor] Adolescent. Adult. Child. Female. Germany. Humans. Infant. Infant, Newborn. Male. Obesity / diagnosis. Obesity / etiology. Obesity / therapy. Practice Guidelines as Topic. Practice Patterns, Physicians'. Treatment Outcome

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15772466.001).
  • [ISSN] 0378-584X
  • [Journal-full-title] Onkologie
  • [ISO-abbreviation] Onkologie
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 24
  •  go-up   go-down


57. Ahmet A, Blaser S, Stephens D, Guger S, Rutkas JT, Hamilton J: Weight gain in craniopharyngioma--a model for hypothalamic obesity. J Pediatr Endocrinol Metab; 2006 Feb;19(2):121-7
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Weight gain in craniopharyngioma--a model for hypothalamic obesity.
  • OBJECTIVES: To evaluate (1) the pattern of post-operative weight gain and (2) the risk factors associated with the development of post-operative weight gain and obesity in children treated for craniopharyngioma.
  • STUDY DESIGN: The records of 43 children who had primary craniopharyngioma resection were reviewed.
  • [MeSH-major] Craniopharyngioma / complications. Craniopharyngioma / surgery. Hypothalamus / physiopathology. Obesity / etiology. Pituitary Neoplasms / complications. Pituitary Neoplasms / surgery. Postoperative Complications
  • [MeSH-minor] Adolescent. Adult. Body Mass Index. Child. Child, Preschool. Female. Follow-Up Studies. Humans. Male. Weight Gain


58. Luu QT, Loredo LN, Archambeau JO, Yonemoto LT, Slater JM, Slater JD: Fractionated proton radiation treatment for pediatric craniopharyngioma: preliminary report. Cancer J; 2006 Mar-Apr;12(2):155-9
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fractionated proton radiation treatment for pediatric craniopharyngioma: preliminary report.
  • This retrospective preliminary review evaluated the efficacy and toxicity of fractionated proton radiotherapy in the management of pediatric craniopharyngioma.
  • All had undergone at least one tumor resection.
  • DISCUSSION: Fractionated proton radiotherapy is an effective treatment for children with craniopharyngioma.
  • [MeSH-major] Craniopharyngioma / therapy. Pituitary Neoplasms / therapy. Protons / therapeutic use. Radiotherapy, Conformal / methods
  • [MeSH-minor] Adolescent. Adult. California / epidemiology. Child. Dose Fractionation. Female. Humans. Male. Radiotherapy, Adjuvant. Retrospective Studies. Salvage Therapy / methods

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16630407.001).
  • [ISSN] 1528-9117
  • [Journal-full-title] Cancer journal (Sudbury, Mass.)
  • [ISO-abbreviation] Cancer J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Protons
  •  go-up   go-down


59. Elliott RE, Moshel YA, Wisoff JH: Minimal residual calcification and recurrence after gross-total resection of craniopharyngioma in children. J Neurosurg Pediatr; 2009 Apr;3(4):276-83
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Minimal residual calcification and recurrence after gross-total resection of craniopharyngioma in children.
  • OBJECT: The purpose of this study was to assess the impact of minimal residual calcification without enhancing tumor on the rate of recurrence after gross-total resection (GTR) of craniopharyngioma in children.
  • METHODS: Data were retrospectively collected in 86 patients younger than 21 years of age in whom 103 craniopharyngioma resections were performed by the senior author between 1986 and 2008.
  • Forty-nine patients (27 boys and 22 girls, with a mean age of 8.6 years) fulfilled the criteria for inclusion in this study by having tumor calcification on the preoperative CT scan, undergoing GTR, and having complete postoperative CT and MR imaging and clinical follow-up.
  • At a mean follow-up of 9.4 years (median 10 years), 2 (15%) of 13 patients with and 10 (28%) of 36 patients without residual calcification experienced tumor recurrence.
  • CONCLUSIONS: The absence or presence of minimal residual calcification does not have an impact on the risk of recurrence after GTR in pediatric craniopharyngiomas.
  • The authors recommend withholding irradiation or other adjuvant therapy in the setting of minimal residual calcification without enhancing tumor.
  • [MeSH-major] Calcinosis / complications. Craniopharyngioma / pathology. Craniopharyngioma / surgery. Neoplasm Recurrence, Local / epidemiology. Pituitary Neoplasms / pathology. Pituitary Neoplasms / surgery
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Cohort Studies. Disease-Free Survival. Female. Humans. Infant. Male. Neoplasm, Residual. Retrospective Studies. Risk Factors. Young Adult

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19338405.001).
  • [ISSN] 1933-0707
  • [Journal-full-title] Journal of neurosurgery. Pediatrics
  • [ISO-abbreviation] J Neurosurg Pediatr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


60. Pedreira CC, Stargatt R, Maroulis H, Rosenfeld J, Maixner W, Warne GL, Zacharin MR: Health related quality of life and psychological outcome in patients treated for craniopharyngioma in childhood. J Pediatr Endocrinol Metab; 2006 Jan;19(1):15-24
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Health related quality of life and psychological outcome in patients treated for craniopharyngioma in childhood.
  • Patients with craniopharyngioma are at risk for many adverse effects related to the tumour's invasive behaviour and its proximity to many vital structures.
  • Profound psychosocial problems, memory impairment, pituitary and hypothalamic dysfunction in addition to the physical handicap of visual loss are frequently recognized sequelae of craniopharyngioma treatment.
  • OBJECTIVES: To examine health related quality of life (QoL) and psychological outcomes of patients treated for craniopharyngioma at the Royal Children's Hospital, Melbourne, between January 1980 and September 2003.
  • MEASUREMENTS: The Adult GH-Deficient Assessment (AGHDA) and Psychological General Well-Being (PGWB) questionnaires were employed to assess quality of life in patients and age- and sex-matched healthy controls.
  • Few craniopharyngioma survivors (18/30) were available for evaluation, demonstrating difficulties in attempts to assess this complex group.
  • CONCLUSIONS: Craniopharyngioma and its treatment result in significant, complex medical, social, psychological and emotional difficulties.
  • [MeSH-major] Craniopharyngioma / psychology. Hypothalamus / physiopathology. Pituitary Neoplasms / psychology. Quality of Life / psychology
  • [MeSH-minor] Activities of Daily Living / psychology. Adolescent. Adult. Child. Child, Preschool. Female. Follow-Up Studies. Humans. Infant. Intelligence Tests. Male. Neuropsychological Tests. Obesity / etiology. Obesity / psychology. Self-Assessment. Treatment Outcome

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] J Pediatr Endocrinol Metab. 2006 Jan;19(1):11-3 [16509523.001]
  • (PMID = 16509524.001).
  • [ISSN] 0334-018X
  • [Journal-full-title] Journal of pediatric endocrinology & metabolism : JPEM
  • [ISO-abbreviation] J. Pediatr. Endocrinol. Metab.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] England
  •  go-up   go-down


61. Nishizawa S, Ohta S, Oki Y: Spontaneous resolution of diabetes insipidus after pituitary stalk sectioning during surgery for large craniopharyngioma. Endocrinological evaluation and clinical implications for surgical strategy. Neurol Med Chir (Tokyo); 2006 Mar;46(3):126-34; discussion 134-5
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spontaneous resolution of diabetes insipidus after pituitary stalk sectioning during surgery for large craniopharyngioma. Endocrinological evaluation and clinical implications for surgical strategy.
  • The mechanism of spontaneous resolution of diabetes insipidus (DI) was investigated after surgery for large craniopharyngioma.
  • Twenty-two adult patients (mean age 48.9 years old), who underwent surgery via the anterior interhemispheric trans-lamina terminalis approach, were divided into three groups: Group I, the entire pituitary stalk was preserved (n = 2); Group II, the stalk was dissected distally from the tumor but ultimately sacrificed (n = 9); Group III, the stalk was not identified and was sacrificed (n = 11).
  • Four patients underwent gamma-knife treatment for residual tumor or recurrence.
  • [MeSH-major] Craniopharyngioma / surgery. Diabetes Insipidus / surgery. Pituitary Gland / surgery. Pituitary Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Female. Follow-Up Studies. Humans. Hypothalamo-Hypophyseal System / physiopathology. Male. Middle Aged. Remission, Spontaneous


62. Müller HL, Müller-Stöver S, Gebhardt U, Kolb R, Sörensen N, Handwerker G: Secondary narcolepsy may be a causative factor of increased daytime sleepiness in obese childhood craniopharyngioma patients. J Pediatr Endocrinol Metab; 2006 Apr;19 Suppl 1:423-9
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Secondary narcolepsy may be a causative factor of increased daytime sleepiness in obese childhood craniopharyngioma patients.
  • Prognosis in childhood craniopharyngioma survivors hinges upon late effects such as pituitary deficiency and obesity.
  • We analyzed the degree of daytime sleepiness in 115 childhood craniopharyngioma patients (47% obese) using the Epworth Sleepiness Scale (ESS).
  • Polysomnography (PSG) and Multiple Sleep Latency Tests (MSLT) were conducted with 10 obese patients presenting increased daytime sleepiness, with only two craniopharyngioma patients revealing a sleep related breathing disorder.
  • We speculate that secondary narcolepsy is an exacerbating condition of childhood craniopharyngioma obesity, supported by recent reports on orexin and narcolepsy which suggest hypothalamic failure in idiopathic narcolepsy.
  • [MeSH-major] Craniopharyngioma / complications. Narcolepsy / etiology. Obesity / complications. Pituitary Neoplasms / complications
  • [MeSH-minor] Adolescent. Adult. Body Mass Index. Central Nervous System Stimulants / therapeutic use. Child. Cohort Studies. Female. HLA Antigens / metabolism. Humans. Male. Polysomnography. Risk Factors. Sleep / physiology. Sleep Stages

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • Genetic Alliance. consumer health - Narcolepsy.
  • MedlinePlus Health Information. consumer health - Obesity.
  • MedlinePlus Health Information. consumer health - Obesity in Children.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16700320.001).
  • [ISSN] 0334-018X
  • [Journal-full-title] Journal of pediatric endocrinology & metabolism : JPEM
  • [ISO-abbreviation] J. Pediatr. Endocrinol. Metab.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Central Nervous System Stimulants; 0 / HLA Antigens
  •  go-up   go-down


63. Maiter D, Abs R, Johannsson G, Scanlon M, Jönsson PJ, Wilton P, Koltowska-Häggström M: Baseline characteristics and response to GH replacement of hypopituitary patients previously irradiated for pituitary adenoma or craniopharyngioma: data from the Pfizer International Metabolic Database. Eur J Endocrinol; 2006 Aug;155(2):253-60
MedlinePlus Health Information. consumer health - Radiation Therapy.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Baseline characteristics and response to GH replacement of hypopituitary patients previously irradiated for pituitary adenoma or craniopharyngioma: data from the Pfizer International Metabolic Database.
  • OBJECTIVE: To test the hypothesis whether the effects of GH replacement therapy in adults could be affected by prior pituitary irradiation, the baseline characteristics and response to GH were evaluated in adults with severe GH deficiency (GHD), who had received or not irradiation for the treatment of pituitary adenoma or craniopharyngioma.
  • CONCLUSIONS: This analysis shows that prior irradiation for pituitary adenoma or craniopharyngioma does not compromise the beneficial effects of GH replacement therapy.

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16868138.001).
  • [ISSN] 0804-4643
  • [Journal-full-title] European journal of endocrinology
  • [ISO-abbreviation] Eur. J. Endocrinol.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 12629-01-5 / Human Growth Hormone
  •  go-up   go-down


64. Pemberton LS, Dougal M, Magee B, Gattamaneni HR: Experience of external beam radiotherapy given adjuvantly or at relapse following surgery for craniopharyngioma. Radiother Oncol; 2005 Oct;77(1):99-104
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Experience of external beam radiotherapy given adjuvantly or at relapse following surgery for craniopharyngioma.
  • BACKGROUND AND PURPOSE: Evaluation of effect of timing of external beam radiation therapy (EBRT) following surgery for craniopharyngioma.
  • [MeSH-major] Craniopharyngioma / radiotherapy. Craniopharyngioma / surgery. Pituitary Neoplasms / radiotherapy. Pituitary Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Age Factors. Aged. Child. Child, Preschool. Combined Modality Therapy. Disease-Free Survival. Female. Humans. Infant. Male. Middle Aged. Morbidity. Neoplasm Recurrence, Local / radiotherapy. Radiotherapy, Adjuvant. Retrospective Studies. Time Factors

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16216361.001).
  • [ISSN] 0167-8140
  • [Journal-full-title] Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
  • [ISO-abbreviation] Radiother Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
  •  go-up   go-down


65. Fitzek MM, Linggood RM, Adams J, Munzenrider JE: Combined proton and photon irradiation for craniopharyngioma: long-term results of the early cohort of patients treated at Harvard Cyclotron Laboratory and Massachusetts General Hospital. Int J Radiat Oncol Biol Phys; 2006 Apr 1;64(5):1348-54
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Combined proton and photon irradiation for craniopharyngioma: long-term results of the early cohort of patients treated at Harvard Cyclotron Laboratory and Massachusetts General Hospital.
  • PURPOSE: We report the results of the early cohort of patients treated for craniopharyngioma with combined proton-photon irradiation at the Massachusetts General Hospital and the Harvard Cyclotron Laboratory.
  • METHODS AND MATERIALS: Between 1981 and 1988, 15 patients with craniopharyngioma were treated in part or entirely with fractionated 160 MeV proton beam therapy.
  • Median dose prescribed to the tumor was 56.9 cobalt Gray equivalent (CGE; 1 proton Gray = 1.1 CGE).
  • One patient was lost to follow-up with tumor control after 5.2 years.
  • The functional status of the living adult patients is unaltered from their preradiotherapy status; all of them continued leading normal or near normal working lives.
  • None of the patients treated as a child had experienced recurrence of tumor.
  • [MeSH-major] Craniopharyngioma / radiotherapy. Photons / therapeutic use. Pituitary Neoplasms / radiotherapy. Protons / therapeutic use
  • [MeSH-minor] Achievement. Adolescent. Adult. Child. Cyclotrons. Educational Status. Female. Humans. Male. Middle Aged. Survival Rate. Thyroid Hormones / administration & dosage. Visual Fields / radiation effects

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16580494.001).
  • [ISSN] 0360-3016
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P01 CA 21239
  • [Publication-type] Journal Article; Multicenter Study; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Protons; 0 / Thyroid Hormones
  •  go-up   go-down


66. Yang I, Sughrue ME, Rutkowski MJ, Kaur R, Ivan ME, Aranda D, Barani IJ, Parsa AT: Craniopharyngioma: a comparison of tumor control with various treatment strategies. Neurosurg Focus; 2010 Apr;28(4):E5
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Craniopharyngioma: a comparison of tumor control with various treatment strategies.
  • OBJECT: Craniopharyngiomas have a propensity to recur after resection, potentially causing death through their aggressive local behavior in their critical site of origin.
  • Recent data suggest that subtotal resection (STR) followed by adjuvant radiotherapy (XRT) may be an appealing substitute for gross-total resection (GTR), providing similar rates of tumor control without the morbidity associated with aggressive resection.
  • Here, the authors summarize the published literature regarding rates of tumor control with various treatment modalities for craniopharyngiomas.
  • METHODS: The authors performed a comprehensive search of the English language literature to identify studies publishing outcome data on patients undergoing surgery for craniopharyngioma.
  • RESULTS: There were 442 patients who underwent tumor resection.
  • CONCLUSIONS: Given the relative rarity of craniopharyngioma, this study provides estimates of outcome for a variety of treatment combinations, as not all treatments are an option for all patients with these tumors.
  • [MeSH-major] Craniopharyngioma / therapy. Pituitary Neoplasms / therapy
  • [MeSH-minor] Adolescent. Adult. Age Factors. Aged. Child. Child, Preschool. Disease-Free Survival. Female. Humans. Hypophysectomy / methods. Kaplan-Meier Estimate. Male. Middle Aged. Pituitary Irradiation. Radiotherapy, Adjuvant. Treatment Outcome

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20367362.001).
  • [ISSN] 1092-0684
  • [Journal-full-title] Neurosurgical focus
  • [ISO-abbreviation] Neurosurg Focus
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 282
  •  go-up   go-down


67. Metzler-Baddeley C, Jones RW: Brief communication: cognitive rehabilitation of executive functioning in a case of craniopharyngioma. Appl Neuropsychol; 2010 Oct;17(4):299-304
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Brief communication: cognitive rehabilitation of executive functioning in a case of craniopharyngioma.
  • Craniopharyngiomas are rare brain tumors within the area of the craniopharyngeal duct.
  • This single-case report describes a brief investigation into the effectiveness of goal management training for dysexecutive problems following the removal and treatment of a craniopharyngioma in a young woman.
  • Thus, the exploitation of naturally occurring external distractions as periodic alerts to facilitate goal management can be an effective and easy-to-adopt cognitive rehabilitation strategy for dysexecutive problems associated with craniopharyngioma.
  • [MeSH-major] Cognition Disorders / rehabilitation. Cognitive Therapy / methods. Craniopharyngioma / complications. Craniopharyngioma / rehabilitation. Executive Function / physiology
  • [MeSH-minor] Adult. Female. Humans. Neuropsychological Tests

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21154044.001).
  • [ISSN] 1532-4826
  • [Journal-full-title] Applied neuropsychology
  • [ISO-abbreviation] Appl Neuropsychol
  • [Language] eng
  • [Publication-type] Case Reports; Clinical Conference; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


68. Jonklaas J: Atypical presentation of a patient with both kallmann syndrome and a craniopharyngioma: case report and literature review. Endocr Pract; 2005 Jan-Feb;11(1):30-6
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Atypical presentation of a patient with both kallmann syndrome and a craniopharyngioma: case report and literature review.
  • OBJECTIVE: To describe an unusual presentation of a patient with Kallmann syndrome, without the typical eunuchoid features, who had additional hormonal abnormalities caused by a craniopharyngioma.
  • A literature search was also performed to determine whether the combination of craniopharyngioma and Kallmann syndrome had been described previously.
  • RESULTS: A 23-year-old man had a suprasellar tumor in conjunction with hypogonadotropic hypogonadism and growth hormone deficiency.
  • No prior reports of craniopharyngioma in a patient with Kallmann syndrome could be identified.
  • CONCLUSION: It is postulated that although this patient had Kallmann syndrome, he did not present with a eunuchoid body habitus because of concomitant growth hormone deficiency caused by his craniopharyngioma.
  • Although midline craniofacial abnormalities have been seen in patients with Kallmann syndrome, this patient's craniopharyngioma seems more likely to be coincidental, rather than being one of the developmental anomalies that are part of the spectrum of this syndrome.
  • [MeSH-major] Craniopharyngioma / complications. Craniopharyngioma / diagnosis. Kallmann Syndrome / complications. Kallmann Syndrome / diagnosis. Pituitary Neoplasms / complications. Pituitary Neoplasms / diagnosis
  • [MeSH-minor] Adult. Human Growth Hormone / deficiency. Humans. Magnetic Resonance Imaging. Male

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • Genetic Alliance. consumer health - Kallmann syndrome.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16033733.001).
  • [ISSN] 1530-891X
  • [Journal-full-title] Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
  • [ISO-abbreviation] Endocr Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 12629-01-5 / Human Growth Hormone
  • [Number-of-references] 42
  •  go-up   go-down


69. Hasegawa T, Kobayashi T, Kida Y: Tolerance of the optic apparatus in single-fraction irradiation using stereotactic radiosurgery: evaluation in 100 patients with craniopharyngioma. Neurosurgery; 2010 Apr;66(4):688-94; discussion 694-5
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tolerance of the optic apparatus in single-fraction irradiation using stereotactic radiosurgery: evaluation in 100 patients with craniopharyngioma.
  • OBJECTIVE: To determine the limiting dose to the optic apparatus in single-fraction irradiation in patients with craniopharyngioma treated with gamma knife radiosurgery (GKRS).
  • METHODS: One hundred patients with 109 craniopharyngiomas treated with GKRS were evaluated with a median follow-up period of 68 months.
  • Tumor volume varied from 0.1 to 36.0 (median, 3.3) cm.
  • RESULTS: The actuarial 5- and 10-year overall rates of survival of tumor progression after GKRS were 93% and 88%, respectively.
  • [MeSH-major] Craniopharyngioma / surgery. Pituitary Neoplasms / surgery. Radiosurgery / methods. Vision, Ocular / physiology
  • [MeSH-minor] Adolescent. Adult. Disease-Free Survival. Dose-Response Relationship, Radiation. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Optic Chiasm / radiation effects. Optic Nerve Diseases / etiology. Radiotherapy Dosage. Retrospective Studies. Time Factors

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20190668.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


70. Qiu SJ, Guo YL, Zhang XL, Zhang F, Zhang YZ, Wen G, Hu BS: [Imaging findings of craniopharyngioma in relation to its surgical management: a retrospective analysis]. Nan Fang Yi Ke Da Xue Xue Bao; 2007 Jul;27(7):980-2
MedlinePlus Health Information. consumer health - MRI Scans.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Imaging findings of craniopharyngioma in relation to its surgical management: a retrospective analysis].
  • Of the 123 craniopharyngioma patients, 59 were found to have adamantinous craniopharyngiomas, 41 had papillary squamous craniopharyngiomas, and 23 had mixed tumors.
  • Solid tumor was found in 18 cases, cystic tumor in 38 cases, and calcification in 78 cases; in 23 cases, the posterior of the tumor did not exhibit clear boundary from the wall of the three cerebral ventricles, and in 11 cases CT and MRI displayed hypophysial stalk, which was found intraoperatively in 53 cases.
  • CONCLUSIONS: MRI allows clear vision of the range of craniopharyngioma involvement and the anatomical structures surrounding the tumor.
  • Accurate identification of the site, dimension, calcification patterns and relation between the hypophysial stalk and hypothalamus by the imaging modalities significantly benefits the optimization of the surgical plan for the tumor.
  • [MeSH-major] Craniopharyngioma / diagnosis. Craniopharyngioma / surgery. Magnetic Resonance Imaging. Tomography, X-Ray Computed
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Cohort Studies. Female. Humans. Infant. Male. Middle Aged. Retrospective Studies. Young Adult

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - CT Scans.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17666331.001).
  • [ISSN] 1673-4254
  • [Journal-full-title] Nan fang yi ke da xue xue bao = Journal of Southern Medical University
  • [ISO-abbreviation] Nan Fang Yi Ke Da Xue Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  •  go-up   go-down


71. Schultes B, Ernst B, Schmid F, Thurnheer M: Distal gastric bypass surgery for the treatment of hypothalamic obesity after childhood craniopharyngioma. Eur J Endocrinol; 2009 Jul;161(1):201-6
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Distal gastric bypass surgery for the treatment of hypothalamic obesity after childhood craniopharyngioma.
  • OBJECTIVE: Our goal was to describe the course of hypothalamic obesity in a craniopharyngioma patient treated with distal gastric bypass surgery and to outline distinct aspects of multidisciplinary case management.
  • PATIENT AND METHODS: A 29-year-old man, who had undergone craniopharyngioma resection at the age of 8, was referred to our Interdisciplinary Obesity Centre with a body mass index (BMI) of 52.0 kg/m(2), type 2 diabetes and obstructive sleep apnoea syndrome (OSAS).


72. Joosen P, Abrams P, Verhelst J, Parizel PM, Salgado R, Abs R: Panhypopituitarism apparently caused by hypophysitis masking a rapid development of a craniopharyngioma. A case report. Acta Clin Belg; 2010 Mar-Apr;65(2):133-5
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Panhypopituitarism apparently caused by hypophysitis masking a rapid development of a craniopharyngioma. A case report.
  • Diagnosis of papillary craniopharyngioma was finally made.
  • This case demonstrates the remarkably rapid development of a craniopharyngioma, which initial radiological appearance was suggestive of hypophysitis.
  • [MeSH-major] Craniopharyngioma / diagnosis. Hypopituitarism / pathology. Pituitary Neoplasms / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Male


73. Müller HL, Gebhardt U, Wessel V, Schröder S, Kolb R, Sörensen N, Maroske J, Hanisch E: First experiences with laparoscopic adjustable gastric banding (LAGB) in the treatment of patients with childhood craniopharyngioma and morbid obesity. Klin Padiatr; 2007 Nov-Dec;219(6):323-5
MedlinePlus Health Information. consumer health - Weight Loss Surgery.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] First experiences with laparoscopic adjustable gastric banding (LAGB) in the treatment of patients with childhood craniopharyngioma and morbid obesity.
  • Craniopharyngiomas are embryogenic malformations which lead to eating disorders and morbid obesity due to hypothalamic involvement in about 50% of all patients with pediatric craniopharyngioma.
  • The experience with laparoscopic adjustable gastric banding (LAGB) in obese craniopharyngioma patients is limited.
  • We are reporting on four patients with childhood craniopharyngioma diagnosed at age 2, 11, 12, and 21 years.
  • We conclude that LAGB could be effective in weight reduction of obese craniopharyngioma patients with hypothalamic syndrome.
  • Close follow-up is necessary in order to analyze long-term effects and complications of LAGB in patients with childhood craniopharyngioma and morbid obesity.
  • [MeSH-major] Craniopharyngioma / complications. Gastroplasty. Laparoscopy. Obesity, Morbid / etiology. Obesity, Morbid / surgery. Pituitary Neoplasms / complications
  • [MeSH-minor] Adolescent. Adult. Body Mass Index. Child. Female. Follow-Up Studies. Humans. Male. Time Factors. Treatment Outcome

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • Genetic Alliance. consumer health - Obesity.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18050042.001).
  • [ISSN] 0300-8630
  • [Journal-full-title] Klinische Pädiatrie
  • [ISO-abbreviation] Klin Padiatr
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  •  go-up   go-down


74. Aquilina K, O'Brien DF, Farrell MA, Bolger C: Primary cerebellopontine angle craniopharyngioma in a patient with gardner syndrome. Case report and review of the literature. J Neurosurg; 2006 Aug;105(2):330-3
Genetic Alliance. consumer health - Gardner Syndrome.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary cerebellopontine angle craniopharyngioma in a patient with gardner syndrome. Case report and review of the literature.
  • The authors report on the case of a craniopharyngioma arising in the cerebellopontine angle (CPA) in a patient with Gardner syndrome.
  • Although familial adenomatous polyposis (FAP) is associated with intracranial neoplasms, the current case is only the third reported craniopharyngioma in a patient with Gardner syndrome.
  • Two of these tumors, including that of the current case, originated in the CPA, an unusual location for craniopharyngiomas.
  • The literature concerning FAP and its associations with intracranial neoplasia, as well as the pathogenesis of craniopharyngiomas in the posterior fossa, is discussed.
  • [MeSH-major] Cerebellar Neoplasms / genetics. Cerebellar Neoplasms / surgery. Cerebellopontine Angle / pathology. Cerebellopontine Angle / surgery. Craniopharyngioma / surgery. Gardner Syndrome / surgery
  • [MeSH-minor] Adult. Cerebellum / pathology. Cerebellum / surgery. Diagnosis, Differential. Fibroma / diagnosis. Fibroma / genetics. Fibroma / pathology. Fibroma / surgery. Humans. Magnetic Resonance Imaging. Male. Neoplasms, Multiple Primary / diagnosis. Neoplasms, Multiple Primary / genetics. Neoplasms, Multiple Primary / pathology. Neoplasms, Multiple Primary / surgery. Scalp / pathology. Scalp / surgery. Skin Neoplasms / diagnosis. Skin Neoplasms / genetics. Skin Neoplasms / pathology. Skin Neoplasms / surgery

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17219843.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 24
  •  go-up   go-down


75. Qi S, Huang G, Pan J, Li J, Zhang X, Fang L, Liu B, Meng W, Zhang Y, Liu X: Involvement of osteopontin as a core protein in craniopharyngioma calcification formation. J Neurooncol; 2010 May;98(1):21-30
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Involvement of osteopontin as a core protein in craniopharyngioma calcification formation.
  • To investigate the role of OPN in craniopharyngioma calcification formation, we studied the involvement of OPN and CD44v6 in craniopharyngiomas.
  • Immunohistochemical staining was used in human craniopharyngiomas to detect the relationship of OPN and degree of calcification, and immunogold localization of OPN was done to identify cell secretory granules.
  • OPN expression was elevated in calcification craniopharyngioma samples.
  • These results suggest that OPN is possibly involved as a core protein in the formation of craniopharyngioma calcification.
  • [MeSH-major] Calcinosis / metabolism. Craniopharyngioma / metabolism. Osteopontin / metabolism. Pituitary Neoplasms / metabolism
  • [MeSH-minor] Adolescent. Adult. Aged. Antigens, CD44 / metabolism. Child. Child, Preschool. Epithelium / pathology. Epithelium / ultrastructure. Humans. Magnetic Resonance Imaging / methods. Male. Microscopy, Immunoelectron / methods. Middle Aged. Retrospective Studies. Tomography, X-Ray Computed / methods. Young Adult

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19902145.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD44; 0 / CD44v6 antigen; 106441-73-0 / Osteopontin
  •  go-up   go-down


76. Kobayashi T: Long-term results of gamma knife radiosurgery for 100 consecutive cases of craniopharyngioma and a treatment strategy. Prog Neurol Surg; 2009;22:63-76
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term results of gamma knife radiosurgery for 100 consecutive cases of craniopharyngioma and a treatment strategy.
  • A new treatment strategy using the gamma knife is proposed, based on evaluation of long-term results of gamma knife radiosurgery for residual or recurrent craniopharyngioma after microsurgery.
  • The mean volume of tumor was 3.5 ml.
  • Final overall results: complete response 19.4%, partial response 67.4%, tumor control rate 79.6% and progression rate 20.4%.
  • Age (for adults) and nature of tumor (cystic or mixed) were statistically significantly favorable and unfavorable prognostic factors, respectively.
  • The strategy is for a small tumor between the retrochiasm and anterior stalk to be treated by gamma knife radiotherapy with 10-12 Gy, allowing cure without neuroendocrine deficits.
  • [MeSH-major] Craniopharyngioma / pathology. Craniopharyngioma / surgery. Pituitary Neoplasms / pathology. Pituitary Neoplasms / surgery. Radiosurgery
  • [MeSH-minor] Adolescent. Adult. Age Factors. Child. Child, Preschool. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Microsurgery. Middle Aged. Postoperative Complications. Prognosis. Treatment Outcome. Young Adult

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18948720.001).
  • [ISSN] 0079-6492
  • [Journal-full-title] Progress in neurological surgery
  • [ISO-abbreviation] Prog Neurol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
  •  go-up   go-down


77. Pereira AM, Schmid EM, Schutte PJ, Voormolen JH, Biermasz NR, van Thiel SW, Corssmit EP, Smit JW, Roelfsema F, Romijn JA: High prevalence of long-term cardiovascular, neurological and psychosocial morbidity after treatment for craniopharyngioma. Clin Endocrinol (Oxf); 2005 Feb;62(2):197-204
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] High prevalence of long-term cardiovascular, neurological and psychosocial morbidity after treatment for craniopharyngioma.
  • INTRODUCTION: The treatment of craniopharyngiomas is associated with long-term morbidity.
  • AIM OF THE STUDY: To assess the long-term functional outcome and mortality rates after treatment for craniopharyngiomas, we audited our data with special focus on cardiovascular, neurological and psychosocial morbidity.
  • PATIENTS AND METHODS: Between 1965 and 2002, 54 consecutive patients underwent surgery for craniopharyngiomas at the Leiden University Medical Centre (LUMC).
  • CONCLUSION: Craniopharyngioma is associated with excessive long-term multisystem morbidity and mortality, especially in female patients, despite a high cure rate.
  • [MeSH-major] Craniopharyngioma / therapy. Pituitary Neoplasms / therapy
  • [MeSH-minor] Adolescent. Adult. Aged. Cardiovascular Diseases / etiology. Child. Child, Preschool. Disease-Free Survival. Female. Follow-Up Studies. Humans. Male. Middle Aged. Morbidity. Neoplasm Recurrence, Local. Nervous System Diseases / etiology. Prevalence. Risk. Sex Factors. Survival Rate. Time Factors. Visual Acuity. Visual Fields

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15670196.001).
  • [ISSN] 0300-0664
  • [Journal-full-title] Clinical endocrinology
  • [ISO-abbreviation] Clin. Endocrinol. (Oxf)
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 30
  •  go-up   go-down


78. Di Battista E, Naselli A, Queirolo S, Gallarotti F, Garré ML, Milanaccio C, Cama A: Endocrine and growth features in childhood craniopharyngioma: a mono-institutional study. J Pediatr Endocrinol Metab; 2006 Apr;19 Suppl 1:431-7
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endocrine and growth features in childhood craniopharyngioma: a mono-institutional study.
  • OBJECTIVE: To evaluate growth and endocrine features in children with craniopharyngioma who were treated and followed up by a single institution between 1976 and 2004.
  • [MeSH-major] Craniopharyngioma / complications. Endocrine System Diseases / etiology. Growth Disorders / etiology. Pituitary Neoplasms / complications
  • [MeSH-minor] Adolescent. Adult. Anthropometry. Body Height / physiology. Body Weight / physiology. Child. Child, Preschool. Combined Modality Therapy. Female. Follow-Up Studies. Hormones / blood. Humans. Hypothyroidism / etiology. Infant. Male. Pituitary Hormones / blood. Pituitary Hormones / deficiency. Retrospective Studies

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Endocrine Diseases.
  • MedlinePlus Health Information. consumer health - Growth Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16700321.001).
  • [ISSN] 0334-018X
  • [Journal-full-title] Journal of pediatric endocrinology & metabolism : JPEM
  • [ISO-abbreviation] J. Pediatr. Endocrinol. Metab.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Hormones; 0 / Pituitary Hormones
  •  go-up   go-down


79. van der Klaauw AA, Biermasz NR, Pereira AM, van Kralingen KW, Dekkers OM, Rabe KF, Smit JW, Romijn JA: Patients cured from craniopharyngioma or nonfunctioning pituitary macroadenoma (NFMA) suffer similarly from increased daytime somnolence despite normal sleep patterns compared to healthy controls. Clin Endocrinol (Oxf); 2008 Nov;69(5):769-74
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Patients cured from craniopharyngioma or nonfunctioning pituitary macroadenoma (NFMA) suffer similarly from increased daytime somnolence despite normal sleep patterns compared to healthy controls.
  • OBJECTIVE: Adults patients previously treated for craniopharyngioma have increased general and physical fatigue compared to healthy controls.
  • PATIENTS AND METHODS: Sleepiness and sleep patterns were assessed in 27 adult patients [14 men, 8 patients diagnosed at childhood age, mean age of 53 years (range 27-80 year)] after long-term follow-up and compared to 50 healthy controls and 38 age-, gender- and BMI-matched patients with NFMA.
  • However, daytime sleepiness scores were increased in patients treated for craniopharyngioma compared to healthy controls, but not different from patients with NFMA.
  • Thirty-three percent of patients with craniopharyngiomas had ESS scores above 10 compared to 8% of healthy controls (P = 0.005), indicating severe daytime hypersomnolence.
  • Neither type of surgery, previous radiotherapy, or age at diagnosis influenced the sleepiness scores in patients with craniopharyngioma.
  • CONCLUSION: Patients treated for craniopharyngioma or NFMA have increased daytime somnolence despite normal sleep patterns, compared to healthy subjects.
  • The results indicate that increased daytime somnolence is a general consequence of large tumours, and/or their treatment, in the hypothalamic/pituitary region, rather than a specific feature of craniopharyngiomas per se.
  • [MeSH-major] Adenoma / rehabilitation. Craniopharyngioma / rehabilitation. Disorders of Excessive Somnolence / epidemiology. Pituitary Neoplasms / rehabilitation. Sleep / physiology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Case-Control Studies. Circadian Rhythm / physiology. Female. Health. Humans. Male. Middle Aged. Prevalence. Research Design. Surveys and Questionnaires

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18435832.001).
  • [ISSN] 1365-2265
  • [Journal-full-title] Clinical endocrinology
  • [ISO-abbreviation] Clin. Endocrinol. (Oxf)
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  •  go-up   go-down


80. Simoneau-Roy J, O'Gorman C, Pencharz P, Adeli K, Daneman D, Hamilton J: Insulin sensitivity and secretion in children and adolescents with hypothalamic obesity following treatment for craniopharyngioma. Clin Endocrinol (Oxf); 2010 Mar;72(3):364-70
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Insulin sensitivity and secretion in children and adolescents with hypothalamic obesity following treatment for craniopharyngioma.
  • BACKGROUND: Craniopharyngioma (CP), a tumour occurring in the hypothalamic-pituitary area, results in morbid obesity in 25-60% of affected children.
  • [MeSH-major] Craniopharyngioma / surgery. Insulin Resistance. Obesity / physiopathology. Pituitary Neoplasms / surgery. Postoperative Complications / physiopathology
  • [MeSH-minor] Adolescent. Case-Control Studies. Child. Dyslipidemias / complications. Female. Glucose Tolerance Test. Humans. Hypertension / complications. Hypothalamus / injuries. Insulin / secretion. Male. Young Adult


81. Tena-Suck ML, Ortiz-Plata A, Galán F, Sánchez A: Expression of epithelial cell adhesion molecule and pituitary tumor transforming gene in adamantinomatous craniopharyngioma and its correlation with recurrence of the tumor. Ann Diagn Pathol; 2009 Apr;13(2):82-8
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of epithelial cell adhesion molecule and pituitary tumor transforming gene in adamantinomatous craniopharyngioma and its correlation with recurrence of the tumor.
  • Craniopharyngiomas are benign tumors of the sellar region generally associated with endocrine disorders and often locally aggressive.
  • The reliable criteria for predicting the tumor behavior are still lacking.
  • It has been suggested that proliferative potential of the tumor cells is necessary for recurrence.
  • The aim of this study was to evaluate the activity and correlation of epithelial cell adhesion molecule (Ep-CAM) and pituitary tumor transforming gene (PTTG-1) immunoexpression that is possibly related to relapse in 40 patients with adamantinomatous craniopharyngioma.
  • The PTGG-1 expression in craniopharyngioma may suggest hypophyseal metaplasia.
  • The Ep-CAM and PTTG-1 expression in craniopharyngioma could be used as prediction markers of relapsing tumor.
  • It has been suggested that proliferative potential of the tumor cells is necessary for recurrence.
  • [MeSH-major] Antigens, Neoplasm / biosynthesis. Cell Adhesion Molecules / biosynthesis. Craniopharyngioma / metabolism. Neoplasm Proteins / biosynthesis. Neoplasm Recurrence, Local / metabolism. Pituitary Neoplasms / metabolism
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Female. Gene Expression. Humans. Immunohistochemistry. Male. Securin

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Ann Diagn Pathol. 2009 Dec;13(6):428-9 [19917481.001]
  • (PMID = 19302955.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Cell Adhesion Molecules; 0 / EPCAM protein, human; 0 / Neoplasm Proteins; 0 / Securin; 0 / pituitary tumor-transforming protein 1, human
  •  go-up   go-down


82. Lonjon M, Dran G, Casagrande F, Vandenbos F, Mas JC, Richelme C: Prenatal diagnosis of a craniopharyngioma: a new case with radical surgery and review. Childs Nerv Syst; 2005 Mar;21(3):177-80
MedlinePlus Health Information. consumer health - Prenatal Testing.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Prenatal diagnosis of a craniopharyngioma: a new case with radical surgery and review.
  • CASE REPORT: A case of the antenatal diagnosis of a craniopharyngioma with radical surgery in the neonatal period is reported.
  • Only six cases of the truly antenatal diagnosis of craniopharyngiomas have been reported.
  • Clinically, there is often macrocephaly due to hydrocephalus or a significant-sized tumor.
  • [MeSH-major] Craniopharyngioma / diagnosis. Craniopharyngioma / surgery. Fetal Diseases / diagnosis. Fetal Diseases / surgery. Prenatal Diagnosis
  • [MeSH-minor] Adult. Female. Humans. Magnetic Resonance Imaging / methods. Pregnancy. Review Literature as Topic

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Fetal Health and Development.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15290187.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


83. Jane JA Jr, Kiehna E, Payne SC, Early SV, Laws ER Jr: Early outcomes of endoscopic transsphenoidal surgery for adult craniopharyngiomas. Neurosurg Focus; 2010 Apr;28(4):E9
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Early outcomes of endoscopic transsphenoidal surgery for adult craniopharyngiomas.
  • OBJECT: Although the transsphenoidal approach for subdiaphragmatic craniopharyngiomas has been performed for many years, there are few reports describing the role of the endoscopic transsphenoidal technique for suprasellar craniopharyngiomas.
  • The purpose of this study was to report the outcomes of the endoscopic transsphenoidal approach for adults with craniopharyngiomas in whom the goal was gross-total resection.
  • CONCLUSIONS: The authors have achieved a high rate of radical resection and symptomatic improvement with the endoscopic transsphenoidal technique for both subdiaphragmatic (sellar/suprasellar) and supradiaphragmatic (suprasellar) craniopharyngiomas.
  • Endoscopic assessment of tumor resection may be more sensitive for residual tumor than the first postoperative MR imaging study.
  • [MeSH-major] Craniopharyngioma / surgery. Neuroendoscopy / methods. Neurosurgical Procedures / methods. Pituitary Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Diabetes Insipidus / etiology. Female. Humans. Hypopituitarism / etiology. Magnetic Resonance Imaging. Male. Microsurgery / methods. Middle Aged. Postoperative Complications / etiology. Sella Turcica / pathology. Sella Turcica / surgery. Sphenoid Sinus. Treatment Outcome. Tumor Burden. Vision Disorders / etiology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20367523.001).
  • [ISSN] 1092-0684
  • [Journal-full-title] Neurosurgical focus
  • [ISO-abbreviation] Neurosurg Focus
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


84. Ulfarsson E, Karström A, Yin S, Girnita A, Vasilcanu D, Thoren M, Kratz G, Hillman J, Axelson M, Larsson O, Girnita L: Expression and growth dependency of the insulin-like growth factor I receptor in craniopharyngioma cells: a novel therapeutic approach. Clin Cancer Res; 2005 Jul 1;11(13):4674-80
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression and growth dependency of the insulin-like growth factor I receptor in craniopharyngioma cells: a novel therapeutic approach.
  • Craniopharyngioma is a rare benign intracranial epithelial tumor that, however, often recurs and sometimes kills the affected patients, one-third of which are children.
  • Together, these circumstances raise the question whether IGF-IR may be involved in craniopharyngioma growth.
  • To address this issue, we analyzed phenotypically well-characterized primary low-passage craniopharyngioma cell lines from nine different patients for IGF-IR expression and IGF-I dependency.
  • Taken together, our data suggest that IGF-IR may be involved in the growth of a subset of craniopharyngiomas and points to the possibility of the involvement of IGF-IR inhibitors as a treatment modality to obtain complete tumor-free conditions before growth hormone substitution.
  • [MeSH-major] Craniopharyngioma / pathology. Pituitary Neoplasms / pathology. Receptor, IGF Type 1 / biosynthesis
  • [MeSH-minor] Adolescent. Adult. Cell Proliferation / drug effects. Child. Dose-Response Relationship, Drug. Humans. Immunohistochemistry. Inhibitory Concentration 50. Insulin-Like Growth Factor I / pharmacology. Middle Aged. Phosphorylation / drug effects. Podophyllotoxin / analogs & derivatives. Podophyllotoxin / pharmacology. Tumor Cells, Cultured

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • Hazardous Substances Data Bank. PODOFILOX .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16000560.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0F35AOI227 / picropodophyllin; 67763-96-6 / Insulin-Like Growth Factor I; EC 2.7.10.1 / Receptor, IGF Type 1; L36H50F353 / Podophyllotoxin
  •  go-up   go-down


85. Goldstone AP, Patterson M, Kalingag N, Ghatei MA, Brynes AE, Bloom SR, Grossman AB, Korbonits M: Fasting and postprandial hyperghrelinemia in Prader-Willi syndrome is partially explained by hypoinsulinemia, and is not due to peptide YY3-36 deficiency or seen in hypothalamic obesity due to craniopharyngioma. J Clin Endocrinol Metab; 2005 May;90(5):2681-90
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fasting and postprandial hyperghrelinemia in Prader-Willi syndrome is partially explained by hypoinsulinemia, and is not due to peptide YY3-36 deficiency or seen in hypothalamic obesity due to craniopharyngioma.
  • We measured fasting and postprandial plasma ghrelin in nonobese (n = 16 fasting and n = 8 postprandial) and obese non-PWS adults (n = 16 and 9), adults with genetically confirmed PWS (n = 26 and 10), and patients with hypothalamic obesity from craniopharyngioma tumors (n = 9 and 6).
  • 3) hyperghrelinemia and hypoinsulinemia are not found in craniopharyngioma patients with hypothalamic obesity, and indeed, these patients have relative hyperinsulinemia for their obesity; and 4) there is no deficiency of the anorexigenic intestinal hormone peptide YY(3-36) in PWS contributing to their hyperghrelinemia.
  • [MeSH-major] Craniopharyngioma / blood. Fasting / blood. Hypothalamus / physiology. Insulin / blood. Obesity, Morbid / blood. Peptide Hormones / blood. Peptide YY / deficiency. Pituitary Neoplasms / blood. Prader-Willi Syndrome / blood
  • [MeSH-minor] Adult. Female. Ghrelin. Humans. Hyperphagia / etiology. Insulin Resistance. Male. Middle Aged. Peptide Fragments. Postprandial Period


86. Le BH, Towfighi J, Kapadia SB, Lopes MB: Comparative immunohistochemical assessment of craniopharyngioma and related lesions. Endocr Pathol; 2007;18(1):23-30
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comparative immunohistochemical assessment of craniopharyngioma and related lesions.
  • Craniopharyngiomas (CP), Rathke's cleft cysts (RCC), and sellar xanthogranulomas (XG) are closely related lesions.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Craniopharyngioma / pathology. Keratin-20 / metabolism. Keratin-8 / metabolism. Pituitary Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Central Nervous System Cysts / metabolism. Central Nervous System Cysts / pathology. Child. Child, Preschool. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Reproducibility of Results. Xanthogranuloma, Juvenile / metabolism. Xanthogranuloma, Juvenile / pathology

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17652797.001).
  • [ISSN] 1046-3976
  • [Journal-full-title] Endocrine pathology
  • [ISO-abbreviation] Endocr. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Keratin-20; 0 / Keratin-8
  •  go-up   go-down


87. Zada G, Lin N, Ojerholm E, Ramkissoon S, Laws ER: Craniopharyngioma and other cystic epithelial lesions of the sellar region: a review of clinical, imaging, and histopathological relationships. Neurosurg Focus; 2010 Apr;28(4):E4
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Craniopharyngioma and other cystic epithelial lesions of the sellar region: a review of clinical, imaging, and histopathological relationships.
  • METHODS: The authors performed a review of the literature to identify previous studies describing the etiological relationships and differentiating features of various cystic sellar lesions, including craniopharyngioma (CP), Rathke cleft cyst, xanthogranuloma, and dermoid and epidermoid cysts.
  • Histological features that signify transitional entities beyond simple benign Rathke cleft cysts include squamous metaplasia, stratified squamous epithelium, and ciliated or mucinous goblet cells in squamous-papillary CPs.
  • [MeSH-major] Craniopharyngioma / pathology. Cysts / pathology. Pituitary Neoplasms / pathology. Sella Turcica / pathology
  • [MeSH-minor] Adult. Animals. Central Nervous System Cysts / diagnosis. Central Nervous System Cysts / pathology. Dermoid Cyst / diagnosis. Dermoid Cyst / pathology. Epidermal Cyst / diagnosis. Epidermal Cyst / pathology. Female. Humans. Hypothalamus / pathology. Magnetic Resonance Imaging / statistics & numerical data. Male. Rats

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20367361.001).
  • [ISSN] 1092-0684
  • [Journal-full-title] Neurosurgical focus
  • [ISO-abbreviation] Neurosurg Focus
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 116
  •  go-up   go-down


88. Holmer H, Pozarek G, Wirfält E, Popovic V, Ekman B, Björk J, Erfurth EM: Reduced energy expenditure and impaired feeding-related signals but not high energy intake reinforces hypothalamic obesity in adults with childhood onset craniopharyngioma. J Clin Endocrinol Metab; 2010 Dec;95(12):5395-402
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Reduced energy expenditure and impaired feeding-related signals but not high energy intake reinforces hypothalamic obesity in adults with childhood onset craniopharyngioma.
  • CONTEXT: Obesity is a frequent manifestation of hypothalamic damage from a craniopharyngioma (CP).
  • OBJECTIVE: The aim was to investigate whether energy expenditure and EI differed between childhood onset CP patients and matched population controls and whether these measures were related to hypothalamic damage, as tumor growth into the third ventricle (TGTV).
  • Ghrelin levels were significantly lower in patients, whereas serum insulin and leptin levels were higher (P<0.001), and both ghrelin and insulin correlated significantly to tumor growth.
  • [MeSH-major] Craniopharyngioma / complications. Energy Intake / physiology. Energy Metabolism / physiology. Feeding Behavior / physiology. Hypothalamus / physiopathology. Obesity / etiology. Obesity / physiopathology
  • [MeSH-minor] Adolescent. Adult. Age of Onset. Androgens / therapeutic use. Child. Estrogens / therapeutic use. Female. Ghrelin / blood. Humans. Insulin / blood. Leptin / blood. Male. Middle Aged. Surveys and Questionnaires. Sweden. Thyroxine / therapeutic use

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • Genetic Alliance. consumer health - Obesity.
  • MedlinePlus Health Information. consumer health - Obesity.
  • MedlinePlus Health Information. consumer health - Obesity in Children.
  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. LEVOTHYROXINE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20826582.001).
  • [ISSN] 1945-7197
  • [Journal-full-title] The Journal of clinical endocrinology and metabolism
  • [ISO-abbreviation] J. Clin. Endocrinol. Metab.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Androgens; 0 / Estrogens; 0 / Ghrelin; 0 / Insulin; 0 / Leptin; Q51BO43MG4 / Thyroxine
  •  go-up   go-down


89. Yoshida A, Sen C, Asa SL, Rosenblum MK: Composite pituitary adenoma and craniopharyngioma?: an unusual sellar neoplasm with divergent differentiation. Am J Surg Pathol; 2008 Nov;32(11):1736-41
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Composite pituitary adenoma and craniopharyngioma?: an unusual sellar neoplasm with divergent differentiation.
  • The patient was treated with thyroid radioablation and hormone replacement and followed for 7 years, during which time the tumor grew to 4.6 cm.
  • At transsphenoidal surgery, a tumor consisting of a pituitary adenoma and adamantinomatous craniopharyngiomalike components was resected.
  • This lesion may represent an unusual composite tumor attributable to divergent differentiation of a common precursor.
  • [MeSH-major] Adenoma / pathology. Craniopharyngioma / pathology. Neoplasms, Multiple Primary / pathology. Pituitary Neoplasms / pathology
  • [MeSH-minor] Adult. Atrial Fibrillation / etiology. Humans. Hyperthyroidism / etiology. Immunohistochemistry. Magnetic Resonance Imaging. Male. Neurosurgical Procedures. Thyrotropin / secretion

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18769335.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 9002-71-5 / Thyrotropin
  •  go-up   go-down


90. Verhelst J, Kendall-Taylor P, Erfurth EM, Price DA, Geffner M, Koltowska-Häggström M, Jönsson PJ, Wilton P, Abs R: Baseline characteristics and response to 2 years of growth hormone (GH) replacement of hypopituitary patients with GH deficiency due to adult-onset craniopharyngioma in comparison with patients with nonfunctioning pituitary adenoma: data from KIMS (Pfizer International Metabolic Database). J Clin Endocrinol Metab; 2005 Aug;90(8):4636-43
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Baseline characteristics and response to 2 years of growth hormone (GH) replacement of hypopituitary patients with GH deficiency due to adult-onset craniopharyngioma in comparison with patients with nonfunctioning pituitary adenoma: data from KIMS (Pfizer International Metabolic Database).
  • Patients with hypopituitarism caused by a craniopharyngioma (CP) and/or its treatment have a higher mortality than patients with other etiologies, such as a nonfunctioning pituitary adenoma (NFPA).
  • [MeSH-major] Adenoma / complications. Craniopharyngioma / complications. Human Growth Hormone / therapeutic use. Hypopituitarism / drug therapy. Hypopituitarism / etiology. Pituitary Neoplasms / complications
  • [MeSH-minor] Adult. Age of Onset. Blood Glucose. Body Composition. Comorbidity. Databases, Factual. Fasting. Female. Hemoglobin A, Glycosylated / metabolism. Humans. Insulin-Like Growth Factor I / metabolism. Lipids / blood. Male. Middle Aged. Prevalence. Quality of Life. Treatment Outcome


91. Lin LL, El Naqa I, Leonard JR, Park TS, Hollander AS, Michalski JM, Mansur DB: Long-term outcome in children treated for craniopharyngioma with and without radiotherapy. J Neurosurg Pediatr; 2008 Feb;1(2):126-30
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term outcome in children treated for craniopharyngioma with and without radiotherapy.
  • OBJECT: The authors report the results of surgery alone or in combination with radiotherapy in the management of craniopharyngiomas in children.
  • METHODS: The authors retrospectively reviewed the outcomes in 31 patients treated for craniopharyngiomas at the Department of Radiation Oncology at Washington University in St. Louis and the St. Louis Children's Hospital.
  • CONCLUSIONS: Radiotherapy delivered as part of the initial management of craniopharyngiomas in children or at the time of recurrence provides effective local control.
  • [MeSH-major] Craniopharyngioma / surgery. Pituitary Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Brachytherapy. Child. Child, Preschool. Disease Progression. Disease-Free Survival. Female. Follow-Up Studies. Humans. Infant. Longitudinal Studies. Male. Neoplasm Recurrence, Local / pathology. Phosphorus Radioisotopes / therapeutic use. Postoperative Complications. Radiopharmaceuticals / therapeutic use. Radiotherapy, Adjuvant. Radiotherapy, Conformal. Radiotherapy, High-Energy. Retrospective Studies. Survival Rate. Treatment Outcome

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] J Neurosurg Pediatr. 2008 Feb;1(2):124-5; discussion 125 [18352780.001]
  • (PMID = 18352781.001).
  • [ISSN] 1933-0707
  • [Journal-full-title] Journal of neurosurgery. Pediatrics
  • [ISO-abbreviation] J Neurosurg Pediatr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Phosphorus Radioisotopes; 0 / Radiopharmaceuticals
  •  go-up   go-down


92. Kobayashi T, Kida Y, Mori Y, Hasegawa T: Long-term results of gamma knife surgery for the treatment of craniopharyngioma in 98 consecutive cases. J Neurosurg; 2005 Dec;103(6 Suppl):482-8
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term results of gamma knife surgery for the treatment of craniopharyngioma in 98 consecutive cases.
  • OBJECT: The authors analyzed the long-term outcomes of gamma knife surgery (GKS) for residual or recurrent craniopharyngiomas after microsurgery and the effects of dose reduction.
  • METHODS: A total of 107 patients with craniopharyngiomas were treated with GKS at Komaki City Hospital during the past 12 years, and 98 patients were followed up for 6 to 148 months (mean 65.5 months).
  • The mean tumor diameter and volume were 18.8 mm and 3.5 ml, respectively.
  • These tumors were treated with a maximal dose of 21.8 Gy and a tumor margin dose of 11.5 Gy by using a mean of 4.5 isocenters.
  • Final overall response rates were as follows: complete response 19.4%, partial response 67.4%, tumor control 79.6%, and tumor progression 20.4%.
  • Reducing the tumor margin dose resulted in decreased therapeutic response and increased tumor progression, although the rate of visual and pituitary function loss also decreased.
  • Among the factors examined, age (for adults) and the nature of the tumor (cystic or mixed) were statistically significant favorable and unfavorable prognostic factors, respectively.
  • CONCLUSIONS: Stereotactic GKS is safe and effective, in the long term, as an adjuvant or boost therapy for residual or recurrent craniopharyngiomas after surgical removal and has minimal side effects.
  • [MeSH-major] Craniopharyngioma / surgery. Pituitary Neoplasms / surgery. Radiosurgery
  • [MeSH-minor] Adolescent. Adult. Disease Progression. Female. Humans. Longitudinal Studies. Magnetic Resonance Imaging. Male. Neoplasm Recurrence, Local / surgery. Neoplasm, Residual / surgery. Stereotaxic Techniques. Treatment Outcome

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] J Neurosurg. 2006 Aug;105(2 Suppl):159-60; author reply 160 [16922083.001]
  • (PMID = 16383245.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


93. Baldé NM, Diallo MM, Poirier JY, Sow MS, Brassier G, Lorcy Y: [Long-term outcome of the adult onset craniopharyngiomas]. Ann Endocrinol (Paris); 2007 Jun;68(2-3):186-90
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Long-term outcome of the adult onset craniopharyngiomas].
  • [Transliterated title] Devenir à long-terme des craniopharyngiomes de l'adulte.
  • There is few published series dealing on the long-term outcome of the adult-onset craniopharyngiomas.
  • We report the long term clinical, tomodensitometric and MRI data outcome of 35 (23 woman and 12 men) consecutive adult-onset cured for craniopharyngiomas between 1983 and 2002, and followed-up in Rennes University Hospital.
  • Recurrence of tumour occurred in 8 patients (25.8%) and a tumor progression in 1 case.
  • Two patients had 5 and 6 years treatment by growth hormone (GH), without tumor recurrence.
  • The observed increase of weight after the surgical cure of craniopharyngiomas concerned 22 patients (63%).
  • In conclusion the craniopharyngiomas recurrence is frequent and can appear in very prolonged deadlines after the initial surgery.
  • [MeSH-major] Craniopharyngioma / therapy. Pituitary Neoplasms / therapy
  • [MeSH-minor] Adult. Aged. Female. Follow-Up Studies. Growth Hormone / therapeutic use. Humans. Magnetic Resonance Imaging. Male. Mental Disorders / etiology. Middle Aged. Neoplasm Recurrence, Local. Survival Analysis. Tomography, X-Ray Computed. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17531946.001).
  • [ISSN] 0003-4266
  • [Journal-full-title] Annales d'endocrinologie
  • [ISO-abbreviation] Ann. Endocrinol. (Paris)
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 9002-72-6 / Growth Hormone
  •  go-up   go-down


94. Yomo S, Hayashi M, Chernov M, Tamura N, Izawa M, Okada Y, Hori T, Iseki H: Stereotactic radiosurgery of residual or recurrent craniopharyngioma: new treatment concept using Leksell gamma knife model C with automatic positioning system. Stereotact Funct Neurosurg; 2009;87(6):360-7
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Stereotactic radiosurgery of residual or recurrent craniopharyngioma: new treatment concept using Leksell gamma knife model C with automatic positioning system.
  • BACKGROUND/AIMS: The present study analyzed the initial experience with the application of the original concept of 'robotic microradiosurgery' using Leksell Gamma Knife Model C with automatic positioning system for management of craniopharyngiomas.
  • METHODS: Eighteen patients with residual or recurrent craniopharyngiomas underwent radiosurgery with the use of multiple isocenters, mainly of smaller size, which were positioned compactly within the border of the lesion with resultant improved dose homogeneity, increased average dose within the target, and sharp dose fall outside the treated volume.
  • Mean tumor volume was 1.8 cm(3).
  • RESULTS: Tumor growth was controlled in 17 cases (94%), and its volume reduction was attained in 13 cases (72%).
  • In 3 patients significant shrinkage of the neoplasm after radiosurgery was accompanied by improvement of the visual functions.
  • CONCLUSION: Application of robotic microradiosurgery to the management of residual and recurrent craniopharyngiomas showed promising results during short- to intermediate-term follow-up, providing early tumor shrinkage in the majority of cases as well as sparing of visual and pituitary functions.
  • [MeSH-major] Craniopharyngioma / surgery. Neoplasm Recurrence, Local / surgery. Pituitary Neoplasms / surgery. Radiosurgery / instrumentation. Radiosurgery / methods. Stereotaxic Techniques
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Female. Follow-Up Studies. Humans. Male. Middle Aged. Retrospective Studies. Treatment Outcome. Young Adult

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2009 S. Karger AG, Basel.
  • (PMID = 19752595.001).
  • [ISSN] 1423-0372
  • [Journal-full-title] Stereotactic and functional neurosurgery
  • [ISO-abbreviation] Stereotact Funct Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 42
  •  go-up   go-down


95. Webb SM, Strasburger CJ, Mo D, Hartman ML, Melmed S, Jung H, Blum WF, Attanasio AF, HypoCCS International Advisory Board: Changing patterns of the adult growth hormone deficiency diagnosis documented in a decade-long global surveillance database. J Clin Endocrinol Metab; 2009 Feb;94(2):392-9
Hazardous Substances Data Bank. (L)-ARGININE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Changing patterns of the adult growth hormone deficiency diagnosis documented in a decade-long global surveillance database.
  • BACKGROUND: GH therapy in adult patients with GH deficiency (GHD) was approved over 10 yr ago, and the indication has subsequently gained broad acceptance.
  • RESULTS: Over the decade, there was a decrease in patients enrolled with diagnoses of pituitary adenoma (50.2 to 38.6%; P < 0.001), craniopharyngioma (13.3 to 8.4%; P = 0.005) and pituitary hemorrhage (5.8 to 2.8%; P = 0.001); increases in idiopathic GHD (13.9 to 19.3%; P < 0.001), less common diagnoses (7.4 to 15.8%; P < 0.001), and undefined/unknown diagnoses (1.3 to 8.6%; P < 0.001) were observed.
  • Over the decade (1996--2005), idiopathic GHD was reported for 16.7% of patients, and more than half of these had adult onset GHD.
  • In the idiopathic adult onset group, 40.2% had isolated GHD; 18.3 and 4.4% had a stimulation test GH peak of at least 3.0 and 5.0 microg/liter, respectively.
  • CONCLUSIONS: Significant shifts in diagnostic patterns have occurred since approval of the adult GHD indication, with a trend to less severe forms of GHD.
  • [MeSH-minor] Adult. Age of Onset. Arginine / analysis. Diagnostic Techniques, Endocrine / trends. Female. Growth Hormone-Releasing Hormone / analysis. Humans. Insulin Resistance / physiology. Male. Middle Aged. Pituitary Diseases / complications. Pituitary Diseases / diagnosis

  • Genetic Alliance. consumer health - Adult Growth Hormone Deficiency.
  • Genetic Alliance. consumer health - Growth Hormone Deficiency.
  • MedlinePlus Health Information. consumer health - Growth Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19001512.001).
  • [ISSN] 0021-972X
  • [Journal-full-title] The Journal of clinical endocrinology and metabolism
  • [ISO-abbreviation] J. Clin. Endocrinol. Metab.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Multicenter Study
  • [Publication-country] United States
  • [Chemical-registry-number] 12629-01-5 / Human Growth Hormone; 9034-39-3 / Growth Hormone-Releasing Hormone; 94ZLA3W45F / Arginine
  • [Investigator] Attanasio AF; Terme A; Beck-Peccoz P; Blum WF; Bouillon R; Chanson P; Kremlin-Bicêtre L; Chihara K; Clemmons DR; Cutler GB; Erfurth EM; Hartman M; Ho KY; Jung H; Kleinberg D; Lamberts SW; Melmed S; Robinson LL; Ross RJ; Shimatsu A; Strasburger CJ; Webb SM; Woodmansee W; Zimmermann A
  •  go-up   go-down


96. Schmalisch K, Beschorner R, Psaras T, Honegger J: Postoperative intracranial seeding of craniopharyngiomas--report of three cases and review of the literature. Acta Neurochir (Wien); 2010 Feb;152(2):313-9; discussion 319
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Postoperative intracranial seeding of craniopharyngiomas--report of three cases and review of the literature.
  • PURPOSE: Seeding of craniopharyngioma has been rarely reported.
  • METHODS: The first patient was a 13-year-old boy who had initially undergone radical excision of a suprasellar and retrosellar craniopharyngioma by a right pterional approach.
  • Postoperative MRI showed no evidence of residual tumor.
  • Two years later, MRI revealed a local recurrence and in addition a separated cystic tumor on the right side adjacent to the middle cerebral artery consistent with seeding along the surgical route.
  • On histopathological examination, both, the local recurrent tumor and the distant deposit turned out to be adamantinomatous craniopharyngiomas.
  • The second patient was a 27-year-old woman who was operated on for the first time via a right pterional and 1 year later for a recurrent craniopharyngioma via a transsphenoidal approach.
  • This deposit in the operative pathway was found to be an adamantinomatous craniopharyngioma, as was the initial tumor.
  • The recent control MRT revealed a right parietal intracranial tumor with peripheral contrast enhancement, which was located distant to the former craniotomy.
  • The tumor was removed and histopathological examination revealed an adamantinomatous craniopharyngioma in accordance with the initial tumor.
  • CONCLUSION: Although craniopharyngiomas exhibit a benign histopathological pattern, cerebrospinal fluid seeding along the surgical route or along the CSF pathways has been observed.
  • Ectopic recurrence of craniopharyngioma suggests that meticulous protection of the whole surgical field and careful handling of the tumor during the operation are required.
  • [MeSH-major] Brain Neoplasms / secondary. Craniopharyngioma / secondary. Neoplasm Metastasis / pathology. Neoplasm Seeding. Pituitary Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Craniotomy. Female. Frontal Bone / pathology. Frontal Bone / surgery. Humans. Magnetic Resonance Imaging. Male. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Parietal Bone / pathology. Parietal Bone / surgery. Reoperation. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19859655.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Austria
  • [Number-of-references] 31
  •  go-up   go-down


97. Pekmezci M, Louie J, Gupta N, Bloomer MM, Tihan T: Clinicopathological characteristics of adamantinomatous and papillary craniopharyngiomas: University of California, San Francisco experience 1985-2005. Neurosurgery; 2010 Nov;67(5):1341-9; discussion 1349
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinicopathological characteristics of adamantinomatous and papillary craniopharyngiomas: University of California, San Francisco experience 1985-2005.
  • BACKGROUND: Craniopharyngiomas are rare epithelial tumors that are presumed to arise from the remnants of Rathke's pouch.
  • OBJECTIVE: This study was designed to evaluate the outcome characteristics of craniopharyngiomas treated in a single institution and to determine whether the adamantinomatous craniopharyngioma should be considered more aggressive than a World Health Organization (WHO) grade I neoplasm.
  • METHODS: We identified all patients with craniopharyngioma given their diagnoses at University of California, San Francisco in a 20-year period and performed a retrospective analysis of clinicopathological and outcome characteristics.
  • CONCLUSION: Adamantinomatous craniopharyngioma is a locally aggressive neoplasm with a significant rate of recurrence.
  • This is not in keeping with the current designation of a WHO grade I neoplasm.
  • Given the high numbers of "silent" defects, formal visual field testing should be performed in all patients with craniopharyngiomas.
  • [MeSH-major] Craniopharyngioma / mortality. Craniopharyngioma / surgery. Neoplasm Recurrence, Local / mortality. Pituitary Neoplasms / mortality. Pituitary Neoplasms / surgery. Postoperative Complications / mortality
  • [MeSH-minor] Adolescent. Adult. Aged. California / epidemiology. Child. Child, Preschool. Female. Humans. Infant. Infant, Newborn. Longitudinal Studies. Male. Middle Aged. Prevalence. Risk Assessment. Risk Factors. Survival Analysis. Survival Rate. Treatment Outcome. Young Adult

  • MedlinePlus Health Information. consumer health - After Surgery.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20871436.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


98. Chung TT, Drake WM, Evanson J, Walker D, Plowman PN, Chew SL, Grossman AB, Besser GM, Monson JP: Tumour surveillance imaging in patients with extrapituitary tumours receiving growth hormone replacement. Clin Endocrinol (Oxf); 2005 Sep;63(3):274-9
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: GH replacement is widely used in the management of patients with adult-onset (AO)-GH deficiency (GHD).
  • The aim of this study was to examine the effect of GH replacement in a group of patients with primary tumours of the parasellar region, many of which (e.g. craniopharyngioma, glioma or germ cell tumours) might be anticipated to have a higher recurrence rate than secretory and nonsecretory anterior pituitary tumours.
  • The primary diagnoses were: craniopharyngioma (28), germ cell tumour (8), arachnoid cyst (4), meningioma (4), glioma (4) and mensenchymal tumour (2).
  • [MeSH-major] Brain / pathology. Growth Hormone / therapeutic use. Hormone Replacement Therapy. Hypopituitarism / drug therapy. Magnetic Resonance Imaging. Neoplasm Recurrence, Local / diagnosis
  • [MeSH-minor] Adult. Brain Neoplasms / complications. Brain Neoplasms / therapy. Combined Modality Therapy. Craniopharyngioma / complications. Craniopharyngioma / therapy. Female. Follow-Up Studies. Germinoma / complications. Germinoma / therapy. Glioma / complications. Glioma / therapy. Humans. Male. Middle Aged. Pituitary Irradiation

  • MedlinePlus Health Information. consumer health - Hormone Replacement Therapy.
  • MedlinePlus Health Information. consumer health - MRI Scans.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16117814.001).
  • [ISSN] 0300-0664
  • [Journal-full-title] Clinical endocrinology
  • [ISO-abbreviation] Clin. Endocrinol. (Oxf)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 9002-72-6 / Growth Hormone
  •  go-up   go-down


99. Schneider HJ, Oertel H, Murck H, Pollmächer T, Stalla GK, Steiger A: Night sleep EEG and daytime sleep propensity in adult hypopituitary patients with growth hormone deficiency before and after six months of growth hormone replacement. Psychoneuroendocrinology; 2005 Jan;30(1):29-37
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Night sleep EEG and daytime sleep propensity in adult hypopituitary patients with growth hormone deficiency before and after six months of growth hormone replacement.
  • Bi-directional interactions between the somatotropic system and human sleep patterns are well established.
  • OBJECTIVE: To assess the effects of GH on nocturnal and daytime sleep in adult patients with GHD before and during recombinant human GH (rhGH, Somatropin) replacement therapy.
  • METHODS: Eighteen adult patients with GHD (4 women and 14 men) participated in the study.
  • [MeSH-minor] Adenoma / complications. Adenoma / surgery. Adult. Craniopharyngioma / complications. Craniopharyngioma / surgery. Cross-Over Studies. Dose-Response Relationship, Drug. Double-Blind Method. Female. Hormone Replacement Therapy. Humans. Injections, Subcutaneous. Male. Middle Aged. Neurosurgical Procedures. Pituitary Neoplasms / complications. Pituitary Neoplasms / surgery. Polysomnography / drug effects. Sleep, REM / drug effects

  • Genetic Alliance. consumer health - Adult Growth Hormone Deficiency.
  • Genetic Alliance. consumer health - Growth Hormone Deficiency.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15358440.001).
  • [ISSN] 0306-4530
  • [Journal-full-title] Psychoneuroendocrinology
  • [ISO-abbreviation] Psychoneuroendocrinology
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 12629-01-5 / Human Growth Hormone; 9002-72-6 / Growth Hormone
  •  go-up   go-down


100. Frank G, Pasquini E, Doglietto F, Mazzatenta D, Sciarretta V, Farneti G, Calbucci F: The endoscopic extended transsphenoidal approach for craniopharyngiomas. Neurosurgery; 2006 Jul;59(1 Suppl 1):ONS75-83; discussion ONS75-83
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The endoscopic extended transsphenoidal approach for craniopharyngiomas.
  • The authors present their experience with this technique in 10 patients with craniopharyngiomas.
  • From November 1998 through May 2005, four males and six females with a craniopharyngioma, either purely supradiaphragmatic (six patients) or with a significant suprasellar component (four patients), were treated.
  • Further studies are required to better define the exact location of the tumor with respect to the arachnoidal plane, the extra-arachnoidal craniopharyngioma being the most suitable for a radical removal using a transsphenoidal supradiaphragmatic approach.
  • [MeSH-major] Craniopharyngioma / surgery. Endoscopy / methods. Neurosurgical Procedures / instrumentation. Pituitary Neoplasms / surgery. Sella Turcica / surgery. Sphenoid Sinus / surgery
  • [MeSH-minor] Adult. Cerebrospinal Fluid Rhinorrhea / etiology. Cerebrospinal Fluid Rhinorrhea / physiopathology. Child. Diabetes Insipidus, Neurogenic / etiology. Diabetes Insipidus, Neurogenic / physiopathology. Endocrine System Diseases / etiology. Endocrine System Diseases / physiopathology. Female. Follow-Up Studies. Humans. Hypothalamo-Hypophyseal System / physiopathology. Male. Middle Aged. Obesity / etiology. Obesity / physiopathology. Optic Chiasm / anatomy & histology. Optic Chiasm / pathology. Optic Chiasm / surgery. Pituitary Diseases / etiology. Pituitary Diseases / physiopathology. Postoperative Complications / etiology. Postoperative Complications / physiopathology. Subarachnoid Space / anatomy & histology. Subarachnoid Space / surgery. Treatment Outcome. Vision, Low / etiology. Vision, Low / physiopathology

  • MedlinePlus Health Information. consumer health - Endoscopy.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16888556.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down






Advertisement