[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 100 of about 365
1. Chamadoira C, Cerejo A, Duarte F, Vaz R: [Trigeminal neuralgia caused by contra lateral cerebellopontine angle tumor. A case report]. Neurocirugia (Astur); 2010 Feb;21(1):50-2
MedlinePlus Health Information. consumer health - Trigeminal Neuralgia.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Trigeminal neuralgia caused by contra lateral cerebellopontine angle tumor. A case report].
  • [Transliterated title] Neuralgia del trigémino provocada por un tumor del ángulo ponto-cerebeloso contralateral. Caso clínico.
  • About 1% of cases, have trigeminal neuralgia associated with the presence of ipsilateral lesion of cerebellar-pontine angle.
  • Rarely, trigeminal neuralgia may be due to contralateral posterior fossa tumors.
  • Facial pain completely disappeared after tumor removal.
  • [MeSH-major] Cerebellar Neoplasms / complications. Cerebellopontine Angle / pathology. Neuroma, Acoustic / complications. Trigeminal Neuralgia / etiology
  • [MeSH-minor] Adult. Humans. Magnetic Resonance Imaging. Male. Treatment Outcome

  • Genetic Alliance. consumer health - Trigeminal neuralgia.
  • MedlinePlus Health Information. consumer health - Acoustic Neuroma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20186375.001).
  • [ISSN] 1130-1473
  • [Journal-full-title] Neurocirugía (Asturias, Spain)
  • [ISO-abbreviation] Neurocirugia (Astur)
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  •  go-up   go-down


2. Sousa R, Sá G, Reimão S, Lopes L, Ruivo J, Albuquerque L, Campos J: [Adult cerebellar medulloblastoma: imaging findings in eight cases]. Acta Med Port; 2006 Nov-Dec;19(6):466-70
Genetic Alliance. consumer health - Medulloblastoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Adult cerebellar medulloblastoma: imaging findings in eight cases].
  • Medulloblastoma is a brain tumor of neuroepithelial origin, frequent in children but rare in adults.
  • We report CT and MRI imaging findings of 8 adult patients with cerebellar medulloblastoma.
  • Most were lateral, located in the cerebellar hemisphere (63%).
  • They should be considered in the differential diagnosis of cerebellar tumor in adults, especially if they are hyperdense on CT, with well defined margins, with superficial extension and with dural involvement.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cerebellar Neoplasms / radiography. Medulloblastoma / pathology. Medulloblastoma / radiography
  • [MeSH-minor] Adolescent. Adult. Cerebellum / pathology. Cerebellum / radiography. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Tomography, X-Ray Computed

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17583605.001).
  • [ISSN] 1646-0758
  • [Journal-full-title] Acta médica portuguesa
  • [ISO-abbreviation] Acta Med Port
  • [Language] por
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Portugal
  •  go-up   go-down


3. Kirschen MP, Davis-Ratner MS, Milner MW, Chen SH, Schraedley-Desmond P, Fisher PG, Desmond JE: Verbal memory impairments in children after cerebellar tumor resection. Behav Neurol; 2008;20(1-2):39-53
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Verbal memory impairments in children after cerebellar tumor resection.
  • This study was designed to investigate cerebellar lobular contributions to specific cognitive deficits observed after cerebellar tumor resection.
  • Verbal working memory (VWM) tasks were administered to children following surgical resection of cerebellar pilocytic astrocytomas and age-matched controls.
  • Anatomical MRI scans were used to quantify the extent of cerebellar lobular damage from each patient's resection.
  • These data corroborate neuroimaging studies showing focal cerebellar activation during VWM paradigms, and thereby allow us to predict with greater accuracy which specific neurocognitive processes will be affected by a cerebellar tumor resection.

  • MedlinePlus Health Information. consumer health - Speech and Communication Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Childs Nerv Syst. 1996 Feb;12(2):81-6 [8674086.001]
  • [Cites] Science. 1992 Jan 31;255(5044):556-9 [1736359.001]
  • [Cites] J Neurol. 1992 Apr;239(4):223-7 [1597689.001]
  • [Cites] Philos Trans R Soc Lond B Biol Sci. 1996 Oct 29;351(1346):1397-403; discussion 1403-4 [8941951.001]
  • [Cites] Neuropsychologia. 1997 Jun;35(6):795-812 [9204486.001]
  • [Cites] Neuroimage. 1995 Sep;2(3):221-9 [9343606.001]
  • [Cites] Int Rev Neurobiol. 1997;41:31-60 [9378595.001]
  • [Cites] Int Rev Neurobiol. 1997;41:489-513 [9378605.001]
  • [Cites] Brain. 1997 Oct;120 ( Pt 10):1753-62 [9365368.001]
  • [Cites] J Neurosci. 1997 Dec 15;17(24):9675-85 [9391022.001]
  • [Cites] Stat Med. 1997 Nov 30;16(22):2529-42 [9403954.001]
  • [Cites] Neurosci Lett. 1998 May 15;247(2-3):187-90 [9655624.001]
  • [Cites] Brain. 1998 Nov;121 ( Pt 11):2175-87 [9827776.001]
  • [Cites] Learn Mem. 1997 May-Jun;4(1):49-62 [10456053.001]
  • [Cites] Neuroimage. 1999 Sep;10(3 Pt 1):327-38 [10458945.001]
  • [Cites] Neurology. 1999 Sep 22;53(5):966-73 [10496254.001]
  • [Cites] Br J Psychol. 1964 Nov;55:429-32 [14237884.001]
  • [Cites] Neurol Sci. 2004 Oct;25(4):220-4 [15549508.001]
  • [Cites] Neurology. 2004 Dec 14;63(11):2132-5 [15596762.001]
  • [Cites] Neuroimage. 2005 Jan 15;24(2):332-8 [15627576.001]
  • [Cites] J Neurosurg. 2004 Nov;101(2 Suppl):152-8 [15835102.001]
  • [Cites] Neuropsychologia. 2005;43(9):1227-37 [15949507.001]
  • [Cites] J Clin Oncol. 2005 Aug 1;23(22):5198-204 [16051961.001]
  • [Cites] Ann Neurol. 2005 Oct;58(4):553-60 [16178033.001]
  • [Cites] Brain Lang. 2005 Nov;95(2):304-18 [16246738.001]
  • [Cites] Brain. 2006 Feb;129(Pt 2):306-20 [16317024.001]
  • [Cites] Neuroimage. 2006 Mar;30(1):12-25 [16257240.001]
  • [Cites] Behav Neurol. 2006;17(3-4):187-94 [17148839.001]
  • [Cites] Cerebellum. 2007;6(3):202-13 [17786816.001]
  • [Cites] Neuroreport. 2008 Jan 22;19(2):197-201 [18185108.001]
  • [Cites] Neuropsychologia. 2008 Mar 7;46(4):1020-31 [18177676.001]
  • [Cites] Brain. 2008 May;131(Pt 5):1332-43 [18334535.001]
  • [Cites] Neuropsychologia. 2008;46(7):1940-53 [18342342.001]
  • [Cites] Dev Psychol. 2000 Jan;36(1):109-16 [10645748.001]
  • [Cites] Pediatr Neurol. 2000 Feb;22(2):106-12 [10738915.001]
  • [Cites] Brain. 2000 May;123 ( Pt 5):1041-50 [10775548.001]
  • [Cites] Brain. 2000 May;123 ( Pt 5):1051-61 [10775549.001]
  • [Cites] Biol Psychol. 2000 Oct;54(1-3):1-34 [11035218.001]
  • [Cites] Acta Neurol Scand. 2000 Dec;102(6):363-70 [11125751.001]
  • [Cites] Psychol Med. 2001 Feb;31(2):241-53 [11232912.001]
  • [Cites] J Neurol Neurosurg Psychiatry. 2001 Jul;71(1):114-7 [11413276.001]
  • [Cites] Cereb Cortex. 2001 Nov;11(11):1003-14 [11590110.001]
  • [Cites] Dev Med Child Neurol. 2001 Oct;43(10):685-91 [11665825.001]
  • [Cites] Neuroimage. 2002 Jan;15(1):273-89 [11771995.001]
  • [Cites] J Cogn Neurosci. 2002 Jan 1;14(1):1-10 [11798382.001]
  • [Cites] Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):13336-41 [12244209.001]
  • [Cites] Ann N Y Acad Sci. 2002 Dec;978:318-33 [12582063.001]
  • [Cites] Arch Neurol. 2003 Jul;60(7):965-72 [12873853.001]
  • [Cites] Brain. 2003 Sep;126(Pt 9):1998-2008 [12876140.001]
  • [Cites] Childs Nerv Syst. 2003 Nov;19(10-11):736-43 [12942270.001]
  • [Cites] J Neurosci. 2003 Nov 26;23(34):10809-14 [14645473.001]
  • [Cites] Brain Res Cogn Brain Res. 2003 Dec;18(1):48-57 [14659496.001]
  • [Cites] Neuroimage. 2004 Jan;21(1):154-62 [14741652.001]
  • [Cites] Dev Psychol. 2004 Mar;40(2):177-90 [14979759.001]
  • [Cites] Q J Exp Psychol. 1966 Nov;18(4):362-5 [5956080.001]
  • [Cites] Neuropsychologia. 1971 Dec;9(4):377-87 [5164373.001]
  • [Cites] Cancer. 1983 Jan 15;51(2):233-7 [6821813.001]
  • [Cites] Arch Neurol. 1985 Jul;42(7):697-8 [4015467.001]
  • [Cites] Brain Cogn. 1986 Oct;5(4):428-42 [3580186.001]
  • [Cites] Percept Mot Skills. 1988 Apr;66(2):503-6 [3399326.001]
  • [Cites] Neurology. 1994 Nov;44(11):2047-50 [7969957.001]
  • (PMID = 19491473.001).
  • [ISSN] 0953-4180
  • [Journal-full-title] Behavioural neurology
  • [ISO-abbreviation] Behav Neurol
  • [Language] ENG
  • [Grant] United States / NIMH NIH HHS / MH / MH060234-08; United States / NIMH NIH HHS / MH / R01 MH060234; United States / NIMH NIH HHS / MH / MH060234; United States / NIMH NIH HHS / MH / R01 MH060234-08
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Other-IDs] NLM/ NIHMS124119; NLM/ PMC2745108
  •  go-up   go-down


Advertisement
4. Huber JF, Bradley K, Spiegler BJ, Dennis M: Long-term effects of transient cerebellar mutism after cerebellar astrocytoma or medulloblastoma tumor resection in childhood. Childs Nerv Syst; 2006 Feb;22(2):132-8
MedlinePlus Health Information. consumer health - After Surgery.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term effects of transient cerebellar mutism after cerebellar astrocytoma or medulloblastoma tumor resection in childhood.
  • BACKGROUND: Following cerebellar tumor resection, some patients develop transient cerebellar mutism (TCM).
  • Although the mutism resolves, it is not known whether there are long-term motor speech deficits in patients with TCM that are in excess of those in individuals with cerebellar tumors who had not developed postoperative TCM.
  • METHODS: Long-term survivors of cerebellar tumors resected in childhood who developed TCM were matched to survivors without TCM and to controls.
  • RESULTS: Tumor survivors who had TCM had significantly more ataxic dysarthric speech and slower speech than either those without TCM or controls and were more dysfluent than controls.
  • Tumor survivors without TCM did not differ from controls on ataxic dysarthria or speech rate.
  • [MeSH-major] Astrocytoma / surgery. Cerebellar Neoplasms / surgery. Medulloblastoma / surgery. Mutism / etiology. Postoperative Complications
  • [MeSH-minor] Adolescent. Adult. Analysis of Variance. Case-Control Studies. Child. Dysarthria / etiology. Dysarthria / physiopathology. Follow-Up Studies. Humans. Male. Time Factors

  • Genetic Alliance. consumer health - Cerebellar Astrocytoma, Childhood.
  • Genetic Alliance. consumer health - Medulloblastoma.
  • Genetic Alliance. consumer health - Medulloblastoma, childhood.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Childs Nerv Syst. 2007 May;23(5):477 [17384951.001]
  • [Cites] Int J Neurol. 1970;7(2):302-18 [5499525.001]
  • [Cites] J Neurooncol. 1996 Jul;29(1):91-101 [8817420.001]
  • [Cites] Neuroradiology. 1995 Feb;37(2):104-8 [7760992.001]
  • [Cites] Brain Lang. 2002 Mar;80(3):592-602 [11896659.001]
  • [Cites] Pediatr Neurosurg. 2003 Oct;39(4):179-83 [12944697.001]
  • [Cites] Dev Med Child Neurol. 1992 Dec;34(12 ):1102-9 [1451941.001]
  • [Cites] Pediatr Neurol. 1997 Apr;16(3):218-9 [9165512.001]
  • [Cites] Brain. 2000 Oct;123 ( Pt 10):1985-2004 [11004117.001]
  • [Cites] Lancet Oncol. 2004 Jul;5(7):399-408 [15231246.001]
  • [Cites] Neurology. 1994 Nov;44(11):2040-6 [7969956.001]
  • [Cites] J Neurosurg. 1997 Jan;86(1):13-21 [8988076.001]
  • [Cites] Pediatr Rehabil. 1997 Jan-Mar;1(1):41-4 [9689237.001]
  • [Cites] Neurosurgery. 1996 Jan;38(1):60-5;discussion 66 [8747952.001]
  • [Cites] J Speech Hear Res. 1979 Sep;22(3):627-48 [502519.001]
  • [Cites] J Speech Hear Res. 1969 Sep;12(3):462-96 [5811846.001]
  • [Cites] Neurosurgery. 1995 Nov;37(5):894-8 [8559337.001]
  • [Cites] Neurosurgery. 1995 Nov;37(5):885-93 [8559336.001]
  • [Cites] J Speech Hear Res. 1969 Jun;12(2):246-69 [5808852.001]
  • [Cites] Brain. 2000 May;123 ( Pt 5):1051-61 [10775549.001]
  • [Cites] Childs Nerv Syst. 1998 Apr-May;14(4-5):161-6 [9660116.001]
  • [Cites] Childs Nerv Syst. 1989 Feb;5(1):12-4 [2649239.001]
  • [Cites] J Child Neurol. 2007 Jul;22(7):848-54 [17715277.001]
  • [Cites] Arch Neurol. 1985 Jul;42(7):697-8 [4015467.001]
  • [Cites] J Neurosurg. 1990 Jun;72 (6):959-63 [2187060.001]
  • (PMID = 16155765.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Grant] United States / NICHD NIH HHS / HD / P01 HD 35946
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  •  go-up   go-down


5. Mattos JP, Marenco HA, Campos JM, Faria AV, Queiroz LS, Borges G, Oliveira Ed: Cerebellar glioblastoma multiforme in an adult. Arq Neuropsiquiatr; 2006 Mar;64(1):132-5
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebellar glioblastoma multiforme in an adult.
  • Cerebellar glioblastoma multiforme (GBM) is a rare tumor.
  • In conjunction, we present a literature review including particular issues, clinical data, advances in imaging studies, pathological characteristics, treatment options and the behavior of such malignant tumor.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cerebellum / pathology. Glioblastoma / pathology

  • Genetic Alliance. consumer health - Glioblastoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16622570.001).
  • [ISSN] 0004-282X
  • [Journal-full-title] Arquivos de neuro-psiquiatria
  • [ISO-abbreviation] Arq Neuropsiquiatr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Brazil
  • [Number-of-references] 16
  •  go-up   go-down


6. Aker FV, Ozkara S, Eren P, Peker O, Armağan S, Hakan T: Cerebellar liponeurocytoma/lipidized medulloblastoma. J Neurooncol; 2005 Jan;71(1):53-9
The Weizmann Institute of Science GeneCards and MalaCards databases. gene/protein/disease-specific - MalaCards for cerebellar liponeurocytoma .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebellar liponeurocytoma/lipidized medulloblastoma.
  • Cerebellar liponeurocytoma that has been recently identified as a distinct entity by the World Health Organization is characterized by areas of lipomatous differentiation and apparently by a favorable prognosis.
  • Although, basically all reported cases share a similar histological pattern, i.e. focal accumulations of adiposities in an otherwise typical small cell tumor like central neurocytoma, some clinical properties such as (age, proliferative potential, therapy and survival) are not uniform.
  • The exact biological behavior of this special variant tumor is established.
  • [MeSH-major] Cerebellar Neoplasms / diagnosis. Medulloblastoma / diagnosis. Neoplasms, Adipose Tissue / diagnosis. Neurocytoma / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Treatment Outcome

  • Genetic Alliance. consumer health - Cerebellar Liponeurocytoma.
  • Genetic Alliance. consumer health - Medulloblastoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Neurosurg. 1989 Mar;70(3):385-91 [2915244.001]
  • [Cites] J Neuropathol Exp Neurol. 1983 Nov;42(6):639-47 [6355400.001]
  • [Cites] J Neurosurg. 1995 May;82(5):891-4 [7714617.001]
  • [Cites] Cancer. 1988 Feb 15;61(4):744-9 [3338037.001]
  • [Cites] Hum Pathol. 2002 May;33(5):564-9 [12094385.001]
  • [Cites] Am J Surg Pathol. 1996 Jun;20(6):656-64 [8651344.001]
  • [Cites] Am J Surg Pathol. 2001 Dec;25(12):1551-5 [11717547.001]
  • [Cites] Ultrastruct Pathol. 2001 Jan-Feb;25(1):59-63 [11297321.001]
  • [Cites] Cancer. 1994 Oct 15;74(8):2352-60 [7922986.001]
  • [Cites] Clin Neuropathol. 2000 Nov-Dec;19(6):273-7 [11128619.001]
  • [Cites] Cancer. 1992 Apr 15;69(8):2143-8 [1544120.001]
  • [Cites] Am J Surg Pathol. 1996 Apr;20(4):413-8 [8604807.001]
  • [Cites] Cancer. 1979 Nov;44(5):1839-52 [498051.001]
  • [Cites] J Neurosurg. 2001 Oct;95(4):700-3 [11596966.001]
  • [Cites] Neuropathol Appl Neurobiol. 1993 Feb;19(1):95-8 [8474606.001]
  • [Cites] J Neurosurg. 2001 Aug;95(2):324-31 [11780904.001]
  • [Cites] Arq Neuropsiquiatr. 2002 Sep;60(3-B):725-9 [12364938.001]
  • [Cites] J Clin Oncol. 1993 Apr;11(4):616-22 [8478656.001]
  • [Cites] J Neurosurg. 1989 Apr;70(4):536-44 [2926493.001]
  • [Cites] Acta Neuropathol. 1978 Mar 15;41(3):261-3 [206094.001]
  • [Cites] Arch Pathol Lab Med. 1989 Jan;113(1):84-8 [2910231.001]
  • [Cites] Hum Pathol. 1994 Jul;25(7):730-1 [8026834.001]
  • [Cites] Am J Surg Pathol. 1998 Mar;22(3):338-46 [9500776.001]
  • [Cites] Neuropathol Appl Neurobiol. 1998 Oct;24(5):397-402 [9821171.001]
  • [Cites] Hum Pathol. 1993 Sep;24(9):990-5 [8068063.001]
  • [Cites] Acta Neuropathol. 1994;87(2):217-22 [8171973.001]
  • [Cites] Acta Neuropathol. 1991;81(4):471-3 [2028751.001]
  • [Cites] Clin Neuropathol. 1997 Jul-Aug;16(4):175-9 [9266140.001]
  • (PMID = 15719276.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 33
  •  go-up   go-down


7. Hur H, Jung S, Jung TY, Kim IY: Cerebellar glioblastoma multiforme in an adult. J Korean Neurosurg Soc; 2008 Apr;43(4):194-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebellar glioblastoma multiforme in an adult.
  • Primary cerebellar glioblastoma multiforme (GBM) is a rare tumor in adults that accounts for just 1% of all cases of GBM.
  • Due to their rarity, cerebellar GBMs are not yet completely understood about the pathogenesis and the prognosis.
  • Neurologic examination revealed the presence of cerebellar signs.
  • Magnetic resonance imaging (MRI) showed a 4.5 x 3.6 cm-sized, ill-defined, heterogeneously enhancing mass in the left cerebellum and two patchy hyperintense lesions in the right cerebellum with minimal enhancement.
  • Here, a case of unusual GBM in the cerebellum is reported with review of literature regarding the pathogenesis, the differential diagnosis and prognosis.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Diagn Interv Radiol. 2005 Jun;11(2):83-6 [15957093.001]
  • [Cites] Radiology. 2002 Mar;222(3):715-21 [11867790.001]
  • [Cites] AJNR Am J Neuroradiol. 1995 Mar;16(3):583-9 [7793385.001]
  • [Cites] J Comput Assist Tomogr. 1991 Jan-Feb;15(1):160-2 [1987190.001]
  • [Cites] J Neurosurg. 1987 Dec;67(6):915-8 [2824720.001]
  • [Cites] J Neurosurg Sci. 1985 Jan-Mar;29(1):43-50 [2999352.001]
  • [Cites] Arq Neuropsiquiatr. 1985 Mar;43(1):102-7 [2990393.001]
  • [Cites] J Neurooncol. 1989 Nov;7(4):339-44 [2555454.001]
  • [Cites] Tumori. 1989 Dec 31;75(6):626-9 [2559527.001]
  • [Cites] Neurosurgery. 1987 Aug;21(2):251-5 [3309714.001]
  • [Cites] Br J Radiol. 1985 May;58(689):480-2 [4063702.001]
  • [Cites] Semin Roentgenol. 1990 Jul;25(3):263-78 [2385809.001]
  • [Cites] Semin Roentgenol. 1990 Apr;25(2):155-73 [2349487.001]
  • [Cites] J Neurosurg. 1983 Apr;58(4):589-92 [6298382.001]
  • [Cites] Surg Neurol. 1983 Apr;19(4):373-8 [6301087.001]
  • [Cites] Arq Neuropsiquiatr. 1981 Sep;39(3):350-4 [6275825.001]
  • [Cites] Cancer. 1982 Jul 15;50(2):308-11 [6282439.001]
  • [Cites] Acta Neurochir (Wien). 1980;53(1-2):107-16 [6254346.001]
  • [Cites] Surg Neurol. 1976 Jun;5(6):341-3 [180621.001]
  • [Cites] J Chin Med Assoc. 2004 Jun;67(6):301-4 [15366408.001]
  • [Cites] AJNR Am J Neuroradiol. 2002 Sep;23(8):1369-77 [12223380.001]
  • [Cites] J Neurosurg. 1999 Mar;90(3):546-50 [10067927.001]
  • (PMID = 19096643.001).
  • [ISSN] 2005-3711
  • [Journal-full-title] Journal of Korean Neurosurgical Society
  • [ISO-abbreviation] J Korean Neurosurg Soc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2588262
  • [Keywords] NOTNLM ; Cerebellum / Differential diagnosis / Glioblastoma multiforme / Pathogenesis
  •  go-up   go-down


8. Wells EM, Walsh KS, Khademian ZP, Keating RF, Packer RJ: The cerebellar mutism syndrome and its relation to cerebellar cognitive function and the cerebellar cognitive affective disorder. Dev Disabil Res Rev; 2008;14(3):221-8
ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The cerebellar mutism syndrome and its relation to cerebellar cognitive function and the cerebellar cognitive affective disorder.
  • The postoperative cerebellar mutism syndrome (CMS), consisting of diminished speech output, hypotonia, ataxia, and emotional lability, occurs after surgery in up to 25% of patients with medulloblastoma and occasionally after removal of other posterior fossa tumors.
  • Theories about the pathophysiology of CMS have evolved along with our understanding of the cerebellum as an important structure in the distributive neurocircuitry underlying complex speech, cognition, and behavior.
  • CMS shares many similarities with the cerebellar cognitive affective syndrome, more commonly described in adults and consisting of disturbances of executive function, visuospatial skills, nonmotor language, and affect regulation.
  • [MeSH-major] Brain Damage, Chronic / etiology. Cerebellar Neoplasms / surgery. Cognition Disorders / etiology. Cranial Fossa, Posterior / surgery. Developmental Disabilities / etiology. Medulloblastoma / surgery. Mood Disorders / etiology. Mutism / etiology. Skull Base Neoplasms / surgery. Survivors / psychology
  • [MeSH-minor] Adolescent. Adult. Child. Child Behavior Disorders / diagnosis. Child Behavior Disorders / etiology. Child Behavior Disorders / psychology. Follow-Up Studies. Humans. Risk Factors. Young Adult

  • MedlinePlus Health Information. consumer health - Developmental Disabilities.
  • MedlinePlus Health Information. consumer health - Mood Disorders.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2008 Wiley-Liss, Inc.
  • (PMID = 18924161.001).
  • [ISSN] 1940-5529
  • [Journal-full-title] Developmental disabilities research reviews
  • [ISO-abbreviation] Dev Disabil Res Rev
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 90
  •  go-up   go-down


9. Bishop FS, Liu JK, Chin SS, Fults DW: Recurrent cerebellar hemangioblastoma with enhancing tumor in the cyst wall: case report. Neurosurgery; 2008 Jun;62(6):E1378-9; discussion E1379
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Recurrent cerebellar hemangioblastoma with enhancing tumor in the cyst wall: case report.
  • OBJECTIVE: Hemangioblastomas are the most common primary intra-axial tumors of the adult posterior fossa and the tumors most often associated with von Hippel-Lindau disease.
  • Resection of cerebellar hemangioblastomas involves tumor excision and drainage of associated cysts.
  • The cyst wall is considered devoid of tumor cells and is not excised.
  • We present an unusual variant of a hemangioblastoma that showed pathological evidence of a tumor within the cyst wall that correlated with radiographic cyst wall enhancement in a patient with a recurrent hemangioblastoma.
  • CLINICAL PRESENTATION: A 38-year-old woman with von Hippel-Lindau disease presented with a recurrent cerebellar hemangioblastoma despite two previous operations during which the mural nodule was removed but the cyst wall was not.
  • Histopathological examination showed a capillary hemangioblastoma with tumor tissue inside the cyst wall.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Hemangioblastoma / pathology. Neoplasm Recurrence, Local / pathology. von Hippel-Lindau Disease / pathology
  • [MeSH-minor] Adult. Female. Humans

  • Genetic Alliance. consumer health - Hemangioblastoma.
  • MedlinePlus Health Information. consumer health - Von Hippel-Lindau Disease.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18824960.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


10. Afshar-Oromieh A, Linhart H, Podlesek D, Schrempf W, Schackert G, Krex D: Postoperative cerebellar mutism in adult patients with Lhermitte-Duclos disease. Neurosurg Rev; 2010 Oct;33(4):401-8
MedlinePlus Health Information. consumer health - After Surgery.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Postoperative cerebellar mutism in adult patients with Lhermitte-Duclos disease.
  • Cerebellar mutism (CM) is a rare and severe form of speech and language impairment, mostly diagnosed in children and adolescents and rarely reported in adults.
  • We also report two illustrative cases of CM following surgical treatment of Lhermitte-Duclos disease (LDD; dysplastic gangliocytoma) in two adult patients.
  • LDD is a rare benign cerebellar tumor.
  • However, surgery is hampered by the difficulty to distinguish between tumor and healthy cerebellar tissue, which may result in extensive resection and cause neurological deficits such as CM.
  • Despite the severity, CM carries a favorable prognosis and generally resolves within a few months.To conclude, we review the clinical signs and particularly the pathophysiological observations and anatomical structures affected in the development of postoperative CM and contribute two cases illustrating the pathogenesis, prognosis, and possible prevention of this syndrome, to focus that CM might also occur in adults even in association with rare tumors.
  • [MeSH-minor] Adolescent. Adult. Aged. Cerebellar Diseases / etiology. Cerebellar Diseases / pathology. Cerebellar Diseases / psychology. Cerebellar Neoplasms / pathology. Cerebellar Neoplasms / surgery. Cerebellum / pathology. Cerebellum / surgery. Epilepsy, Absence / etiology. Ganglioneuroma / pathology. Ganglioneuroma / surgery. Headache / etiology. Humans. Magnetic Resonance Imaging. Middle Aged. Neurosurgical Procedures. Prognosis. Tomography, X-Ray Computed. Young Adult

  • Genetic Alliance. consumer health - Lhermitte-Duclos disease.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Pediatr Neurol. 2004 Jan;30(1):71-4 [14738957.001]
  • [Cites] Acta Neurol (Napoli). 1993 Aug;15(4):289-96 [8249672.001]
  • [Cites] Behav Cogn Neurosci Rev. 2004 Mar;3(1):14-22 [15191639.001]
  • [Cites] Dev Disabil Res Rev. 2008;14(3):221-8 [18924161.001]
  • [Cites] Surg Neurol. 1991 Oct;36(4):307-9 [1948632.001]
  • [Cites] Br J Neurosurg. 1997 Aug;11(4):341-3 [9337934.001]
  • [Cites] Pediatr Neurosurg. 1998 Jun;28(6):328 [9782212.001]
  • [Cites] Neurol Med Chir (Tokyo). 1997 Dec;37(12 ):929-33 [9465594.001]
  • [Cites] Childs Nerv Syst. 1998 Mar;14 (3):114-9 [9579866.001]
  • [Cites] J Chin Med Assoc. 2006 Jul;69(7):338-42 [16903650.001]
  • [Cites] Ann N Y Acad Sci. 2002 Dec;978:318-33 [12582063.001]
  • [Cites] J Neurosurg. 1995 Sep;83(3):467-75 [7666224.001]
  • [Cites] Brain. 1992 Feb;115 Pt 1:155-78 [1559151.001]
  • [Cites] Dev Med Child Neurol. 1997 Oct;39(10):686-90 [9352731.001]
  • [Cites] Childs Nerv Syst. 2005 Mar;21(3):234-6 [15290193.001]
  • [Cites] Neuroradiology. 2004 May;46(5):351-4 [15088131.001]
  • [Cites] Pediatr Neurosurg. 2003 Oct;39(4):179-83 [12944697.001]
  • [Cites] Acta Neurochir (Wien). 1990;105(1-2):44-9 [2239379.001]
  • [Cites] J Exp Psychol Gen. 2000 Mar;129(1):126-45 [10756490.001]
  • [Cites] AJNR Am J Neuroradiol. 2001 May;22(5):824-30 [11337322.001]
  • [Cites] J Neurosurg. 2006 Feb;104(2):329-31 [16509510.001]
  • [Cites] Cerebellum. 2007;6(3):202-13 [17786816.001]
  • [Cites] Childs Nerv Syst. 1998 Sep;14 (9):460-2 [9808255.001]
  • [Cites] Exp Brain Res. 2005 Mar;161(3):383-96 [15558254.001]
  • [Cites] Neuroradiology. 2007 Sep;49(9):733-8 [17549467.001]
  • [Cites] Brain Res Cogn Brain Res. 1993 Apr;1(2):94-9 [8513244.001]
  • [Cites] Surg Neurol. 1999 Feb;51(2):181-4 [10029425.001]
  • [Cites] Clin Neurol Neurosurg. 2001 Jul;103(2):105-10 [11516554.001]
  • [Cites] Surg Neurol. 1994 Apr;41(4):342-4 [8165509.001]
  • [Cites] Neurology. 1994 Nov;44(11):2040-6 [7969956.001]
  • [Cites] Pediatr Rehabil. 1997 Jan-Mar;1(1):41-4 [9689237.001]
  • [Cites] Neurosurgery. 1996 Jan;38(1):60-5;discussion 66 [8747952.001]
  • [Cites] J Neurooncol. 2000 May;48(1):75-81 [11026700.001]
  • [Cites] Neurochirurgie. 2008 Aug;54(4):548-50 [18495179.001]
  • [Cites] Neurosurgery. 1995 Nov;37(5):894-8 [8559337.001]
  • [Cites] Childs Nerv Syst. 1995 May;11(5):306-10 [7648574.001]
  • [Cites] Acta Neurochir (Wien). 2008 Jun;150(6):545-50; discussion 550 [18512000.001]
  • [Cites] Arch Neurol. 2003 Jul;60(7):965-72 [12873853.001]
  • [Cites] Childs Nerv Syst. 1998 Nov;14 (11):611-3 [9840359.001]
  • [Cites] Acta Neurol Scand. 2002 Mar;105(3):137-45 [11886354.001]
  • [Cites] J Cogn Neurosci. 1999 Sep;11(5):491-501 [10511638.001]
  • [Cites] Neurosurgery. 1995 Nov;37(5):885-93 [8559336.001]
  • [Cites] Lancet. 1999 Mar 27;353(9158):1057-61 [10199354.001]
  • [Cites] Acta Neurochir (Wien). 1979;48(1-2):1-15 [495234.001]
  • [Cites] Acta Neurochir (Wien). 2002 May;144(5):463-73 [12111502.001]
  • [Cites] Neurosurgery. 1995 Apr;36(4):854-7 [7596521.001]
  • [Cites] Surg Neurol. 2006 Jul;66(1):18-25 [16793430.001]
  • [Cites] Brain. 2000 May;123 ( Pt 5):1051-61 [10775549.001]
  • [Cites] Surg Neurol. 2005 May;63(5):476-9 [15883080.001]
  • [Cites] J Neurosurg. 2006 Dec;105(6 Suppl):444-51 [17184075.001]
  • [Cites] Br J Neurosurg. 1997 Apr;11(2):161-3 [9156007.001]
  • [Cites] Childs Nerv Syst. 1989 Feb;5(1):12-4 [2649239.001]
  • [Cites] Ann Nucl Med. 2001 Apr;15(2):157-60 [11448076.001]
  • [Cites] Surg Neurol. 2009 Oct;72(4):369-75 [19604553.001]
  • [Cites] Clin Neurol Neurosurg. 1991;93(4):313-6 [1665764.001]
  • [Cites] Childs Nerv Syst. 2009 Jun;25(6):677-81 [19082829.001]
  • [Cites] J Neurol. 2004 Aug;251(8):963-72 [15316801.001]
  • [Cites] Ann N Y Acad Sci. 2002 Dec;978:302-17 [12582062.001]
  • [Cites] Acta Neurochir (Wien). 2003 Jun;145(6):509-12; discussion 512 [12836078.001]
  • [Cites] Brain Res. 1990 Dec 10;535(2):313-7 [2073609.001]
  • [Cites] Arch Neurol. 1985 Jul;42(7):697-8 [4015467.001]
  • [Cites] J Neurosurg. 2004 Sep;101(3):484-98 [15352607.001]
  • [Cites] Pediatr Neurosurg. 1990-1991;16(1):25-31; discussion 31 [2133406.001]
  • [Cites] J Neurosurg. 1994 Jul;81(1):115-21 [8207512.001]
  • [Cites] Neurol India. 2004 Dec;52(4):510-1 [15626850.001]
  • (PMID = 20668902.001).
  • [ISSN] 1437-2320
  • [Journal-full-title] Neurosurgical review
  • [ISO-abbreviation] Neurosurg Rev
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  •  go-up   go-down


11. Nomura M, Hasegawa M, Kita D, Yamashita J, Minato H, Nakazato Y: Cerebellar gliofibroma with numerous psammoma bodies. Clin Neurol Neurosurg; 2006 Jun;108(4):421-5
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebellar gliofibroma with numerous psammoma bodies.
  • Computed tomography (CT) showed a high-density mass without contrast enhancement in the right cerebellar hemisphere.
  • Pathological examinations revealed a biphasic pattern consisting of tumor cells in sparce cellularity and dense fibrous connective tissue.
  • The tumor cells expressed glial fibrillary acidic protein and S-100, but not p53, vimentin and EMA.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Fibroma / pathology. Glioma / pathology. Inclusion Bodies / pathology
  • [MeSH-minor] Adult. Calcinosis / complications. Calcinosis / pathology. Craniotomy. Female. Humans. Magnetic Resonance Imaging

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16644412.001).
  • [ISSN] 0303-8467
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  •  go-up   go-down


12. Akar S, Drappatz J, Hsu L, Blinder RA, Black PM, Kesari S: Hypertrophic olivary degeneration after resection of a cerebellar tumor. J Neurooncol; 2008 May;87(3):341-5
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hypertrophic olivary degeneration after resection of a cerebellar tumor.
  • We report a case of hypertrophic olivary degeneration due to cerebellar surgery for a low-grade tumor.
  • A 27-year-old female presented with right-sided paresthesias and intermittent leg paresis following a right cerebellar resection of a tumor 2 weeks prior.
  • Hypertrophic olivary degeneration may be mistaken for tumor progression, post-operative vasculopathy or granulation tissue and should be considered in patients undergoing cerebellar surgery.
  • [MeSH-major] Astrocytoma / surgery. Cerebellar Neoplasms / surgery. Neurosurgical Procedures / adverse effects. Olivary Nucleus / pathology
  • [MeSH-minor] Adult. Ataxia / etiology. Diagnosis, Differential. Female. Humans. Hypertrophy. Hypesthesia / etiology. Magnetic Resonance Imaging. Neoplasm Recurrence, Local / pathology

  • Genetic Alliance. consumer health - Cerebellar Degeneration.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Arq Neuropsiquiatr. 2003 Jun;61(2B):473-7 [12894288.001]
  • [Cites] J Neurosurg. 2004 Apr;100(4):717 [15070130.001]
  • [Cites] Mov Disord. 1997 May;12(3):432-7 [9159743.001]
  • [Cites] Acta Neuropathol. 1981;54(4):275-82 [7270084.001]
  • [Cites] Brain. 2002 Jun;125(Pt 6):1348-57 [12023323.001]
  • [Cites] Clin Imaging. 1999 Jul-Aug;23(4):215-7 [10631896.001]
  • [Cites] Eur J Paediatr Neurol. 2007 Jul;11(4):232-4 [17400009.001]
  • [Cites] Neuroradiology. 1993;35(5):335-8 [8327105.001]
  • [Cites] J Neurol Neurosurg Psychiatry. 2003 Jun;74(6):797-9 [12754356.001]
  • [Cites] Arq Neuropsiquiatr. 2005 Jun;63(2A):321-3 [16100982.001]
  • [Cites] Radiology. 1999 Dec;213(3):814-7 [10580959.001]
  • [Cites] Pediatr Radiol. 1998 Nov;28(11):830-1 [9799311.001]
  • [Cites] Eur Neurol. 1998;39(2):97-102 [9520070.001]
  • [Cites] AJNR Am J Neuroradiol. 2000 Jun-Jul;21(6):1073-7 [10871017.001]
  • [Cites] AJNR Am J Neuroradiol. 1994 Oct;15(9):1715-9 [7847219.001]
  • [Cites] Neurology. 1991 Apr;41(4):557-62 [2011257.001]
  • [Cites] Radiology. 1994 Aug;192(2):539-43 [8029428.001]
  • (PMID = 18217209.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


13. Fancellu R, Pareyson D, Corsini E, Salsano E, Laurà M, Bernardi G, Antozzi C, Andreetta F, Colecchia M, Di Donato S, Mariotti C: Immunological reactivity against neuronal and non-neuronal antigens in sporadic adult-onset cerebellar ataxia. Eur Neurol; 2009;62(6):356-61
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Immunological reactivity against neuronal and non-neuronal antigens in sporadic adult-onset cerebellar ataxia.
  • In recent years, the involvement of the immune system in acquired forms of cerebellar ataxia has been frequently demonstrated.
  • In this study, we describe 6 out of 49 patients with subacute or chronic progressive cerebellar ataxia in whom antibodies against neuronal and non-neuronal antigens were identified.
  • Two women had anti-Yo antibodies; two patients had anti-gliadin antibodies in the presence of celiac disease; one patient had a complex autoimmune disorder associated with anti-Ro-52/SS-A and anti-muscle-specific kinase antibodies, and a patient developed subacute cerebellar syndrome associated with the presence of a prostatic adenocarcinoma and atypical antibodies reacting both with cerebellar tissue and with the prostatic tumor.
  • Our study confirms previous findings in paraneoplastic syndromes, and indicates that at least 10% of sporadic cerebellar ataxia may be related to immune-mediated mechanisms.
  • [MeSH-minor] Adenocarcinoma / complications. Adenocarcinoma / immunology. Blotting, Western. Celiac Disease / complications. Celiac Disease / immunology. Electromyography. Enzyme-Linked Immunosorbent Assay. Female. Gliadin / immunology. Glutamate Decarboxylase / immunology. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Male. Middle Aged. Nerve Tissue Proteins / immunology. Neurons / immunology. Prostatic Neoplasms / complications. Prostatic Neoplasms / immunology. Ribonucleoproteins / immunology

  • Genetic Alliance. consumer health - Cerebellar Ataxia.
  • Genetic Alliance. consumer health - Ataxia.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19786780.001).
  • [ISSN] 1421-9913
  • [Journal-full-title] European neurology
  • [ISO-abbreviation] Eur. Neurol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Autoantibodies; 0 / CDR2 protein, human; 0 / Nerve Tissue Proteins; 0 / Ribonucleoproteins; 0 / SS-A antigen; 9007-90-3 / Gliadin; EC 4.1.1.15 / Glutamate Decarboxylase
  •  go-up   go-down


14. Roth J, Nass D, Ram Z: Cerebellar tumor extension as a late event of long-standing, supratentorial low-grade gliomas: case report. Neurosurgery; 2006 Jun;58(6):E1210; discussion E1210
MedlinePlus Health Information. consumer health - MRI Scans.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebellar tumor extension as a late event of long-standing, supratentorial low-grade gliomas: case report.
  • OBJECTIVE AND IMPORTANCE: Nonpilocytic low-grade glial tumors in adults occur mostly in the supratentorial compartment.
  • The occurrence of LGG in the cerebellum in the setting of a previously existing supratentorial glioma is rare.
  • All three patients presented years after their initial diagnosis with a second, nonenhancing lesion in the cerebellum, compatible with the radiological appearance of LGG.
  • Two patients subsequently became symptomatic from these lesions and underwent surgical resection of the cerebellar lesions that were found to have similar pathological features to the original supratentorial tumors.
  • INTERVENTION: Magnetic resonance imaging did not demonstrate tumor continuity between the supratentorial and infratentorial lesions in any of the patients.
  • The third patient has shown no cerebellar symptoms to date and is only followed with periodic magnetic resonance imaging.
  • CONCLUSION: The anatomic/pathological basis of these rare cases may include a primary, multicentric tumor formation, or a secondary tumor infiltration of the cerebrocerebellar pathways, leading to the formation of the cerebellar tumor.
  • [MeSH-major] Cerebellar Neoplasms / diagnosis. Glioma / diagnosis. Magnetic Resonance Imaging. Neoplasms, Second Primary / diagnosis. Supratentorial Neoplasms / diagnosis
  • [MeSH-minor] Adult. Female. Humans. Male. Middle Aged

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16723871.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


15. García Casales Z, Echebarría Barona A, Urberuaga Pascual A, Astigarraga Aguirre I, Burgos Bretones JJ, Navajas Gutiérrez A: [Differential aspects in children and adult patients with medulloblastoma]. Med Clin (Barc); 2009 Oct 3;133(12):454-9
Genetic Alliance. consumer health - Medulloblastoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Differential aspects in children and adult patients with medulloblastoma].
  • [Transliterated title] Meduloblastoma: aspectos diferenciales entre el tumor infantil y del adulto.
  • BACKGROUND AND OBJECTIVE: Medulloblastoma is the more frequent malignant cerebral tumor in childhood.
  • Tumor site and mortality according to initial dissemination were variables of statistic significance.
  • Sequelae were detected in 100% of the survivors, mainly with cerebellar and ocular alterations.
  • [MeSH-major] Cerebellar Neoplasms. Medulloblastoma
  • [MeSH-minor] Adolescent. Adult. Age Factors. Child. Child, Preschool. Cohort Studies. Confidence Intervals. Data Interpretation, Statistical. Female. Follow-Up Studies. Humans. Infant. Male. Middle Aged. Neoplasm Metastasis. Normal Distribution. Retrospective Studies. Spain / epidemiology. Statistics, Nonparametric. Time Factors

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19674760.001).
  • [ISSN] 0025-7753
  • [Journal-full-title] Medicina clínica
  • [ISO-abbreviation] Med Clin (Barc)
  • [Language] spa
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Spain
  •  go-up   go-down


16. Grahovac G, Tomac D, Lambasa S, Zoric A, Habek M: Cerebellar glioblastomas: pathophysiology, clinical presentation and management. Acta Neurochir (Wien); 2009 Jun;151(6):653-7
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebellar glioblastomas: pathophysiology, clinical presentation and management.
  • Glioblastoma multiforme usually affects the cerebral hemispheres with the peak age of onset in the sixth or seventh decade, while cerebellar glioblastoma multiforme is a rare tumour especially in younger patients.
  • We report a 28 year old patient with primary multi-focal cerebellar glioblastoma multiforme and review the pathophysiology, clinical presentation, diagnosis and treatment of cerebellar glioblastomas.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Genetic Predisposition to Disease / genetics. Glioblastoma / pathology. Mutation / genetics. Tumor Suppressor Protein p53 / genetics
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Biomarkers, Tumor / metabolism. Cerebellum / pathology. Cerebellum / radiography. Cerebellum / surgery. Fatal Outcome. Female. Fourth Ventricle / pathology. Fourth Ventricle / surgery. Headache / etiology. Humans. Hydrocephalus / etiology. Intracranial Hypertension / etiology. Magnetic Resonance Imaging. Neoplasm Recurrence, Local. Neurosurgical Procedures / methods. Reoperation. Tomography, X-Ray Computed. Vomiting / etiology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19319469.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Austria
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Tumor Suppressor Protein p53
  •  go-up   go-down


17. Rumboldt Z, Camacho DL, Lake D, Welsh CT, Castillo M: Apparent diffusion coefficients for differentiation of cerebellar tumors in children. AJNR Am J Neuroradiol; 2006 Jun-Jul;27(6):1362-9
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Apparent diffusion coefficients for differentiation of cerebellar tumors in children.
  • We hypothesized that cerebellar tumors in children can be differentiated by their ADC values.
  • METHODS: Brain MR imaging studies that included ADC maps were retrospectively reviewed in 32 patients with histologically proved cerebellar neoplasm.
  • There were 17 juvenile pilocytic astrocytomas (JPA), 8 medulloblastomas, 5 ependymomas, and 2 rhabdoid (atypical teratoid/rhabdoid tumor [AT/RT]) tumors.
  • Absolute ADC values of contrast-enhancing solid tumor regions and ADC ratios (ADC of solid tumor to ADC of normal-appearing white matter) were compared with the histologic diagnosis.
  • ADC ratios were also significantly different among these 3 tumor types.
  • CONCLUSION: Assessment of ADC values of enhancing solid tumor is a simple and reliable technique for preoperative differentiation of cerebellar tumors in pediatric patients.
  • [MeSH-major] Cerebellar Neoplasms / diagnosis. Diffusion Magnetic Resonance Imaging
  • [MeSH-minor] Adolescent. Adult. Astrocytoma / diagnosis. Astrocytoma / pathology. Child. Child, Preschool. Diagnosis, Differential. Ependymoma / diagnosis. Ependymoma / pathology. Female. Humans. Infant. Male. Medulloblastoma / diagnosis. Medulloblastoma / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Nat Clin Pract Neurol. 2007 Feb;3(2):78-9 [17279080.001]
  • (PMID = 16775298.001).
  • [ISSN] 0195-6108
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


18. Akhaddar A, Belhachmi A, Elasri A, Boulahroud O, Okacha N, Elmostarshid B, Boucetta M: [Cerebellar mutism after removal of a vermian medulloblastoma in an adult]. Neurochirurgie; 2008 Aug;54(4):548-50
MedlinePlus Health Information. consumer health - After Surgery.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Cerebellar mutism after removal of a vermian medulloblastoma in an adult].
  • Cerebellar mutism is a rare postoperative phenomenon that generally occurs in children after resection of a cerebellar mass lesion.
  • A 22-year-old man developed cerebellar mutism after posterior fossa surgery for a mass lesion in the vermis.
  • The tumor was totally removed via a suboccipital approach.
  • Although pathophysiology and the anatomical substrate of cerebellar mutism still remain unclear, it is important that neurosurgeons be aware of this syndrome after posterior fossa surgery in adults.
  • [MeSH-major] Cerebellar Neoplasms / surgery. Medulloblastoma / surgery. Mutism / etiology. Postoperative Complications
  • [MeSH-minor] Adult. Humans. Magnetic Resonance Imaging. Male. Neurosurgical Procedures

  • Genetic Alliance. consumer health - Medulloblastoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18495179.001).
  • [ISSN] 0028-3770
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  •  go-up   go-down


19. Chowdhury FU, Scarsbrook AF: Indium-111 pentetreotide uptake within cerebellar hemangioblastoma in von Hippel-lindau syndrome. Clin Nucl Med; 2008 Apr;33(4):294-6
MedlinePlus Health Information. consumer health - Von Hippel-Lindau Disease.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Indium-111 pentetreotide uptake within cerebellar hemangioblastoma in von Hippel-lindau syndrome.
  • A 38-year-old woman with known von Hippel-Lindau syndrome underwent In-111 pentetreotide (OctreoScan) scintigraphy to evaluate a suspected pancreatic neuroendocrine tumor.
  • The patient had undergone surgical resection of a left adrenal pheochromocytoma and a large right cerebellar hemangioblastoma several years previously.
  • Although there was no evidence for recurrence of pheochromocytoma and no uptake within the pancreatic lesion, there was focal tracer accumulation within the left cerebellar hemisphere.
  • MR imaging of the brain confirmed the presence of recurrent hemangioblastoma in the left cerebellum.
  • [MeSH-major] Cerebellar Neoplasms / radionuclide imaging. Hemangioblastoma / radionuclide imaging. Somatostatin / analogs & derivatives. von Hippel-Lindau Disease / radionuclide imaging
  • [MeSH-minor] Adult. Female. Humans. Radiopharmaceuticals

  • Genetic Alliance. consumer health - Hemangioblastoma.
  • Genetic Alliance. consumer health - Von Hippel-Lindau syndrome.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18356676.001).
  • [ISSN] 0363-9762
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 51110-01-1 / Somatostatin; G083B71P98 / pentetreotide
  •  go-up   go-down


20. Szathmari A, Thiesse P, Galand-desmé S, Mottolese C, Bret P, Jouanneau E, Guyotat J, Lion-François L, Frappaz D: Correlation between pre- or postoperative MRI findings and cerebellar sequelae in patients with medulloblastomas. Pediatr Blood Cancer; 2010 Dec 15;55(7):1310-6
ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Correlation between pre- or postoperative MRI findings and cerebellar sequelae in patients with medulloblastomas.
  • INTRODUCTION: Immediate and delayed cerebellar dysfunction may be expected after surgical resection of a medulloblastoma.
  • Magnetic Resonance Imaging (MRI) was analyzed for the following items: preoperative MRI (ratio of the surface of the tumor/posterior fossa, presence of ventricular dilatation or tonsilar hernia, involvement of the dentate nucleus) and delayed post-operative MRI (amount of cerebellar parenchyma removed, degree of cerebellar atrophy, presence of T1 hypointense regions in remaining cerebellar area and removal of region containing dentate nucleus).
  • These data were correlated with immediate and long-term cerebellar syndrome and daily life repercussions.
  • RESULTS: On preoperative MRI, the ratio of the surface of the tumor/posterior fossa and the presence of tonsilar hernia were significantly correlated with long-term sequelae on speech (respectively P = 0.027 and P = 0.05).
  • On delayed MRI, cerebellar atrophy was inversely correlated with ability to sustain daily tasks (P = 0.002).
  • Hypointense T1 territory in remaining cerebellar parenchyma significantly correlated with immediate post-operative cerebellar syndrome (P = 0.01) and showed a tendency for post-operative mutism (P = 0.087) but was not correlated with any long-term sequelae.
  • CONCLUSION: Increased cranial pressure on initial MRI and cerebellar atrophy detected on subsequent MRI studies correlated with immediate and long-term cerebellar sequelae.
  • [MeSH-major] Cerebellar Neoplasms / surgery. Magnetic Resonance Imaging. Medulloblastoma / surgery. Postoperative Complications
  • [MeSH-minor] Adolescent. Adult. Atrophy. Cerebellum / pathology. Child. Child, Preschool. Combined Modality Therapy. Female. Humans. Infant. Intracranial Hypertension / etiology. Intracranial Hypertension / pathology. Male. Young Adult

  • MedlinePlus Health Information. consumer health - After Surgery.
  • MedlinePlus Health Information. consumer health - MRI Scans.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20981689.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


21. Kawarabuki K, Ohta T, Hashimoto N, Wada K, Maruno M, Yamaki T, Ueda S: Cerebellar glioblastoma genetically defined as a secondary one. Clin Neuropathol; 2005 Mar-Apr;24(2):64-8
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebellar glioblastoma genetically defined as a secondary one.
  • We report here the case of a 29-year-old woman with cerebellar glioblastma.
  • In the present case, tumor lesions were observed in each cerebellar hemisphere.
  • Immunohistochemistry revealed that the tumor cells of the left-side lesion was positive for p53, whereas epidermal growth factor receptors (EGFR) were negative in tumor cells from both sides.
  • Genetic alterations were investigated using a genome DNA microarray (GenoSensor Array 300), which has led us to define this tumor as a secondary glioblastoma.
  • [MeSH-major] Cerebellar Neoplasms / genetics. Glioblastoma / genetics. Neoplasms, Second Primary / genetics
  • [MeSH-minor] Adult. Female. Humans. Oligonucleotide Array Sequence Analysis

  • Genetic Alliance. consumer health - Glioblastoma.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15803805.001).
  • [ISSN] 0722-5091
  • [Journal-full-title] Clinical neuropathology
  • [ISO-abbreviation] Clin. Neuropathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


22. Ueba T, Kadota E, Kano H, Yamashita K, Kageyama N: MATH-1 production by an adult medulloblastoma suggestive of a cerebellar external granule cell precursor origin. J Clin Neurosci; 2008 Jan;15(1):84-7
Genetic Alliance. consumer health - Medulloblastoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] MATH-1 production by an adult medulloblastoma suggestive of a cerebellar external granule cell precursor origin.
  • Radiological, histological and molecular findings in an uncommon adult case of cerebellar medulloblastoma suggested an external granular cell precursor origin.
  • Neuroimaging studies demonstrated a homogeneously enhanced well-circumscribed mass lesion in the right cerebellar hemisphere and she underwent surgery.
  • Postoperative neuronal imaging studies showed that the tumor located in the cerebellar folia had been removed totally.
  • Polymerase chain reaction and immunohistochemical findings revealed the presence of MATH-1, expressed in cerebellar external granule cell precursors during fetal development, in the tumor cells.
  • These findings suggest that the tumor arose from external granule cell precursors of the cerebellum and that it was therefore of neuronal lineage.
  • [MeSH-major] Basic Helix-Loop-Helix Transcription Factors / metabolism. Cerebellar Neoplasms / metabolism. Cerebellar Neoplasms / pathology. Medulloblastoma / metabolism. Medulloblastoma / pathology. Neurons / physiology
  • [MeSH-minor] Adult. Female. Gene Expression Regulation, Neoplastic. Humans. Magnetic Resonance Imaging / methods. Neoplastic Stem Cells / physiology. Phosphopyruvate Hydratase / metabolism

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18032051.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0 / ATOH1 protein, human; 0 / Basic Helix-Loop-Helix Transcription Factors; EC 4.2.1.11 / Phosphopyruvate Hydratase
  •  go-up   go-down


23. Jagannathan J, Lonser RR, Smith R, DeVroom HL, Oldfield EH: Surgical management of cerebellar hemangioblastomas in patients with von Hippel-Lindau disease. J Neurosurg; 2008 Feb;108(2):210-22
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical management of cerebellar hemangioblastomas in patients with von Hippel-Lindau disease.
  • OBJECT: Despite the frequency of cerebellar hemangioblastomas in von Hippel-Lindau (VHL) disease, their optimum contemporary management has not been defined, and is made complex because of the multiple, progressive, and protean nature of the tumors found in patients with this disorder.
  • To examine modern management and outcomes of cerebellar hemangioblastomas in VHL disease, the authors reviewed findings in patients with this disease who underwent resection of cerebellar hemangioblastomas.
  • METHODS: Consecutive patients with VHL disease who underwent surgery for cerebellar hemangioblastoma(s) at the National Institutes of Health were included.
  • Eighty consecutive patients (44 female and 36 male patients) underwent 126 operations for removal of 164 cerebellar hemangioblastomas (age at surgery 37.8+/-10.3 years, follow-up duration 96.0+/-60.3 months).
  • Tumors associated with symptoms were larger (diameter 1.8+/-1.9 cm; volume 2.8+/-3.4 cm3; p<0.05) and more likely to be associated with peritumoral edema or peritumoral cysts (100% associated with edema and/or cyst; p<0.05) than asymptomatic tumors (diameter 1.1+/-0.9 cm; volume 0.7+/-0.4 cm3; 18%).
  • More tumors were located in the posterior (74%) compared with the anterior (26%) half of the cerebellum (p<0.05).
  • Preoperative hydrocephalus resolved after tumor removal in 33 cases (94%) and did not require cerebrospinal fluid diversion.
  • CONCLUSIONS: Symptoms and signs caused by cerebellar hemangioblastomas in VHL disease are associated with edema and peritumoral cyst formation/propagation and are treated safely and effectively with resection.
  • Cerebrospinal fluid diversion is rarely necessary after complete tumor removal in patients with preoperative hydrocephalus.
  • Cerebellar hemangioblastomas are preferentially distributed in the posterior half of the cerebellum, as they are in the brainstem and spinal cord.
  • Tumor recurrence is avoided by meticulous extracapsular resection.
  • [MeSH-major] Cerebellar Neoplasms / surgery. Hemangioblastoma / surgery. von Hippel-Lindau Disease / complications
  • [MeSH-minor] Adult. Ataxia / physiopathology. Brain Edema / physiopathology. Cerebellar Ataxia / physiopathology. Cranial Irradiation. Cysts / physiopathology. Dissection / methods. Electrocoagulation / methods. Female. Follow-Up Studies. Headache / physiopathology. Humans. Hydrocephalus / physiopathology. Male. Microdissection / methods. Postoperative Complications. Radiosurgery. Radiotherapy, Adjuvant. Retrospective Studies. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Von Hippel-Lindau Disease.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18240914.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / /
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Intramural
  • [Publication-country] United States
  •  go-up   go-down


24. Tailor JK, Kim AH, Folkerth RD, Black PM: The development of ring-shaped contrast enhancement in a case of cerebellar dysembryoplastic neuroepithelial tumor: case report. Neurosurgery; 2008 Sep;63(3):E609-10; discussion E610
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The development of ring-shaped contrast enhancement in a case of cerebellar dysembryoplastic neuroepithelial tumor: case report.
  • OBJECTIVE: Dysembryoplastic neuroepithelial tumor (DNT) occurs rarely in the cerebellum.
  • We describe a rare case of cerebellar DNT that developed contrast enhancement after long-term observation and discuss the underlying mechanism and clinical relevance of this unusual phenomenon.
  • CLINICAL PRESENTATION: A 34-year-old woman with known cystic cerebellar lesions presented with increased frequency of vertigo and new onset of truncal ataxia.
  • Magnetic resonance imaging revealed new contrast enhancement in the dominant cystic lesion of the cerebellar vermis without any change in size and shape or evidence of edema.
  • CONCLUSION: This is the first report of the development of contrast enhancement in a previously nonenhancing case of cerebellar DNT.
  • [MeSH-major] Cerebellar Neoplasms / radiography. Contrast Media. Neoplasms, Neuroepithelial / radiography. Teratoma / radiography
  • [MeSH-minor] Adult. Female. Humans. Magnetic Resonance Imaging / methods. Magnetic Resonance Imaging / trends

  • Genetic Alliance. consumer health - Dysembryoplastic Neuroepithelial Tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18812941.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
  •  go-up   go-down


25. Richter S, Schoch B, Kaiser O, Groetschel H, Dimitrova A, Hein-Kropp C, Maschke M, Gizewski ER, Timmann D: Behavioral and affective changes in children and adolescents with chronic cerebellar lesions. Neurosci Lett; 2005 Jun 10-17;381(1-2):102-7
MedlinePlus Health Information. consumer health - Mood Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Behavioral and affective changes in children and adolescents with chronic cerebellar lesions.
  • The aim of the present study was to investigate if clinically relevant affective or behavioral changes as described in adults in the cerebellar affective syndrome by Schmahmann and Sherman [The cerebellar cognitive affective syndrome, Brain 121 (1998) 561-579] are likely to occur as a long-term sequelae of cerebellar vermis lesions in children.
  • Affect and behavior were assessed in children after cerebellar tumor surgery by means of experimenter ratings based on the description of the cerebellar affective syndrome and free ratings by the patients and their parents.
  • Twelve children and adolescents with a former cerebellar astrocytoma surgery without subsequent radiation or chemotherapy participated.
  • [MeSH-major] Cerebellar Diseases / complications. Cerebellar Diseases / diagnosis. Mental Disorders / diagnosis. Mental Disorders / etiology. Mood Disorders / diagnosis. Mood Disorders / etiology
  • [MeSH-minor] Adolescent. Adult. Child. Chronic Disease. Female. Humans. Male

  • MedlinePlus Health Information. consumer health - Cerebellar Disorders.
  • MedlinePlus Health Information. consumer health - Child Mental Health.
  • MedlinePlus Health Information. consumer health - Mental Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15882798.001).
  • [ISSN] 0304-3940
  • [Journal-full-title] Neuroscience letters
  • [ISO-abbreviation] Neurosci. Lett.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
  •  go-up   go-down


26. Tanioka D, Abe T, Ikeda H, Kushima M: [A case of cerebellar tuberculoma]. No Shinkei Geka; 2005 Sep;33(9):919-23
MedlinePlus Health Information. consumer health - Cerebellar Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of cerebellar tuberculoma].
  • We report a case of cerebellar tuberculoma presenting with headache, without any specific data.
  • MRI demonstrated a mass lesion at the right cerebellum, suggesting the presence of a tuberculoma.
  • He underwent total removal of the tumor via the supracerebellar route.
  • The intracranial tuberculoma may be confused with an intracranial neoplasm.
  • In this report, we describe a cerebellar tuberculoma without any abnormal data, suggesting that intracranial tuberculoma should be considered in the differential diagnosis of any intracranial mass lesion.
  • [MeSH-major] Cerebellar Diseases / diagnosis. Tuberculoma / diagnosis
  • [MeSH-minor] Adult. Humans. Magnetic Resonance Imaging. Male

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16164189.001).
  • [ISSN] 0301-2603
  • [Journal-full-title] No shinkei geka. Neurological surgery
  • [ISO-abbreviation] No Shinkei Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


27. Maryniak A, Roszkowski M: [Cognitive and affective disturbances in children after surgical treatment of cerebellar tumors]. Neurol Neurochir Pol; 2005 May-Jun;39(3):202-6
MedlinePlus Health Information. consumer health - Speech and Communication Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Cognitive and affective disturbances in children after surgical treatment of cerebellar tumors].
  • BACKGROUND AND PURPOSE: The cerebellum has been associated with motor control, but more recent studies have extended its contribution to other functions, such as modulation of emotions, behavioral organization or language.
  • The cerebellar cognitive affective syndrome was described primarily in adults.
  • In children, cerebellar lesions are relatively frequent and some are due to neoplasm.
  • MATERIAL AND METHODS: Cognitive and emotional functions were studied in 66 children who underwent surgery for cerebellar pilocytic astrocytoma at the Department of Neurosurgery of the Children Memorial Health Institute.
  • No significant differences between groups of children with different localization of tumor (vermis or cerebellar hemisphere) were observed.
  • CONCLUSIONS: The present study confirms the psychological deficits following cerebellar lesion in children, similar to the cerebellar cognitive affective syndrome reported in adult patients.
  • [MeSH-major] Astrocytoma / surgery. Cerebellar Neoplasms / surgery. Cognition Disorders / etiology. Mood Disorders / etiology. Neurosurgical Procedures / adverse effects. Speech Disorders / etiology
  • [MeSH-minor] Adaptation, Psychological. Adolescent. Adult. Cerebellum / physiopathology. Cerebellum / surgery. Child. Child, Preschool. Female. Humans. Male. Memory Disorders / etiology. Neuropsychological Tests. Parent-Child Relations. Poland. Retrospective Studies

  • MedlinePlus Health Information. consumer health - Mood Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15981157.001).
  • [ISSN] 0028-3843
  • [Journal-full-title] Neurologia i neurochirurgia polska
  • [ISO-abbreviation] Neurol. Neurochir. Pol.
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
  •  go-up   go-down


28. Cornelius JF, Saint-Maurice JP, Bresson D, George B, Houdart E: Hemorrhage after particle embolization of hemangioblastomas: comparison of outcomes in spinal and cerebellar lesions. J Neurosurg; 2007 Jun;106(6):994-8
MedlinePlus Health Information. consumer health - After Surgery.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hemorrhage after particle embolization of hemangioblastomas: comparison of outcomes in spinal and cerebellar lesions.
  • OBJECT: In this study the authors compare the clinical outcomes after particle embolization of hemangioblastomas in the cerebellum and spinal cord.
  • METHODS: Seven patients with hemangioblastomas in the spinal cord (four patients) and cerebellum (three patients) underwent preoperative embolization at the authors' center.
  • The outcome of embolization was favorable in patients with spinal cord hemangioblastomas, but it was unfavorable for those with cerebellar hemangioblastomas; acute tumor bleeding and death occurred in all of the latter cases.
  • CONCLUSIONS: The authors no longer use particle embolization to treat cerebellar hemangioblastomas.
  • [MeSH-major] Cerebellar Neoplasms / therapy. Cerebral Hemorrhage / etiology. Embolization, Therapeutic / adverse effects. Hemangioblastoma / therapy. Postoperative Complications / etiology. Spinal Neoplasms / therapy
  • [MeSH-minor] Adult. Aged. Cerebral Angiography. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Particle Size. Retrospective Studies. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] J Neurosurg. 2008 May;108(5):1063-4; author reply 1064-5 [18447734.001]
  • (PMID = 17564170.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


29. Kasliwal MK, Suri A, Rishi A, Suri V, Sharma BS, Sarkar C: Symptomatic bilateral cerebellar mass lesions: an unusual presentation of intracranial xanthogranuloma. J Clin Neurosci; 2008 Dec;15(12):1401-4
Genetic Alliance. consumer health - Xanthogranuloma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Symptomatic bilateral cerebellar mass lesions: an unusual presentation of intracranial xanthogranuloma.
  • Multicentric bilateral symptomatic cerebellar xanthogranuloma has not been reported previously.
  • We describe a 35-year-old man who presented with a complaint of vertigo, with nystagmus and left-side cerebellar signs found on clinical examination.
  • Radiological evaluation revealed bilateral cerebellar lesions abutting the cerebellopontine angle cistern.
  • The role of histopathology cannot be overemphasized in the diagnosis of this rare lesion and long-term follow-up is advised in cases managed conservatively owing to the propensity of this tumor to grow over time.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Granuloma / pathology. Xanthomatosis / pathology
  • [MeSH-minor] Adult. Humans. Magnetic Resonance Imaging / methods. Male. Tomography, X-Ray Computed / methods

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18952438.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
  •  go-up   go-down


30. Yoshimura J, Nishiyama K, Fukuda M, Watanabe M, Igarashi H, Fujii Y: Adult cerebellopontine angle medulloblastoma originating in the pons mimicking focal brainstem tumor. J Neuroimaging; 2009 Oct;19(4):385-7
Hazardous Substances Data Bank. CHOLINE CHLORIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adult cerebellopontine angle medulloblastoma originating in the pons mimicking focal brainstem tumor.
  • The 3-tesla MR images revealed that the precise region was in the right side of the tegmentum of the lower pons to the inferior cerebellar peduncle and the flocculus.
  • MR spectroscopic imaging is considered to be quite useful for the management of this rare type of brainstem tumor.
  • [MeSH-major] Brain Stem Neoplasms / pathology. Cerebellopontine Angle / pathology. Infratentorial Neoplasms / pathology. Medulloblastoma / pathology. Pons / pathology
  • [MeSH-minor] Adult. Aspartic Acid / analogs & derivatives. Aspartic Acid / metabolism. Choline / metabolism. Diagnosis, Differential. Female. Follow-Up Studies. Functional Laterality. Humans. Magnetic Resonance Imaging. Magnetic Resonance Spectroscopy

  • Genetic Alliance. consumer health - Medulloblastoma.
  • Hazardous Substances Data Bank. (L)-ASPARTIC ACID .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19021841.001).
  • [ISSN] 1552-6569
  • [Journal-full-title] Journal of neuroimaging : official journal of the American Society of Neuroimaging
  • [ISO-abbreviation] J Neuroimaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 30KYC7MIAI / Aspartic Acid; 997-55-7 / N-acetylaspartate; N91BDP6H0X / Choline
  •  go-up   go-down


31. Adamson DC, Dimitrov DF, Bronec PR: Upward transtentorial herniation, hydrocephalus, and cerebellar edema in hypertensive encephalopathy. Neurologist; 2005 May;11(3):171-5
Hazardous Substances Data Bank. FUROSEMIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Upward transtentorial herniation, hydrocephalus, and cerebellar edema in hypertensive encephalopathy.
  • BACKGROUND: Edema of the cerebellum with secondary obstructive hydrocephalus is a rare presentation of hypertensive encephalopathy.
  • Neuroimaging revealed edema of the cerebellar folia with noncommunicating hydrocephalus and upward transtentorial herniation.
  • Differential diagnoses of posterior fossa tumor, rhombencephalitis, and hypertensive encephalopathy were entertained.
  • Repeat imaging revealed near resolution of the obstructive hydrocephalus and cerebellar edema.
  • CONCLUSION: Isolated edema of the cerebellum with upward transtentorial herniation and obstructive hydrocephalus is a rare presentation of hypertensive encephalopathy and should be considered in patients with an acute hypertensive crisis and mental status changes.
  • [MeSH-major] Brain Edema / etiology. Cerebellar Diseases / etiology. Encephalocele / etiology. Hydrocephalus / etiology. Hypertensive Encephalopathy / complications
  • [MeSH-minor] Adult. Blood Pressure / physiology. Cranial Fossa, Posterior / pathology. Diuretics / administration & dosage. Diuretics / therapeutic use. Furosemide / administration & dosage. Furosemide / therapeutic use. Glasgow Coma Scale. Humans. Magnetic Resonance Imaging. Male. Neurodegenerative Diseases / etiology. Tomography, X-Ray Computed. Ventriculoperitoneal Shunt


32. Schoch B, Hogan A, Gizewski ER, Timmann D, Konczak J: Balance control in sitting and standing in children and young adults with benign cerebellar tumors. Cerebellum; 2010 Sep;9(3):324-35
MedlinePlus Health Information. consumer health - After Surgery.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Balance control in sitting and standing in children and young adults with benign cerebellar tumors.
  • Children and young adolescents with chronic surgical cerebellar lesions show persistent balance control problems during standing when lesions affect the deep cerebellar fastigial and adjacent interposed nuclei.
  • Balance control was assessed in 16 patients after surgery of a benign cerebellar tumor in chronic state and healthy age- and gender-matched control subjects.
  • High-resolution MRI scans were acquired in the cerebellar patients.
  • During sitting, 56% of cerebellar patients exhibited trunkal sway outside the range of healthy controls, and 87.5% of cerebellar patients revealed abnormal sway patterns during standing.
  • In patients with surgery <1-year lesions of the inferior cerebellar vermis also had an impact on balance function.
  • Our results corroborate previous evidence that the extent of permanent damage to the deep cerebellar nuclei greatly impacts on the recovery on balance function.
  • [MeSH-major] Cerebellar Neoplasms / surgery. Neurosurgical Procedures / adverse effects. Postoperative Complications / physiopathology. Postural Balance
  • [MeSH-minor] Adolescent. Adult. Biomechanical Phenomena. Cerebellum / pathology. Cerebellum / physiopathology. Cerebellum / surgery. Child. Female. Humans. Male. Posture. Young Adult

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Cancer. 2001 Dec 15;92(12):3155-64 [11753995.001]
  • [Cites] AMA Arch Neurol Psychiatry. 1955 Dec;74(6):653-80 [13268132.001]
  • [Cites] Nat Rev Neurosci. 2004 Oct;5(10):813-9 [15378041.001]
  • [Cites] J Neurol Neurosurg Psychiatry. 2002 Sep;73(3):310-2 [12185166.001]
  • [Cites] Ann Neurol. 1998 Oct;44(4):601-10 [9778258.001]
  • [Cites] Prog Brain Res. 2004;143:353-66 [14653179.001]
  • [Cites] Neuropediatrics. 2006 Dec;37(6):350-8 [17357037.001]
  • [Cites] Neuroscientist. 2004 Jun;10(3):247-59 [15155063.001]
  • [Cites] J Neurophysiol. 2003 Apr;89(4):1844-56 [12612041.001]
  • [Cites] Cereb Cortex. 2004 Oct;14(10):1164-72 [15142954.001]
  • [Cites] Cerebellum. 2008;7(4):602-6 [18949530.001]
  • [Cites] Arch Neurol. 1999 Apr;56(4):421-5 [10199329.001]
  • [Cites] Neuroimage. 2006 Mar;30(1):36-51 [16253526.001]
  • [Cites] Annu Rev Neurosci. 1992;15:403-42 [1575449.001]
  • [Cites] Brain. 2005 Jun;128(Pt 6):1428-41 [15659424.001]
  • [Cites] J Neurol Sci. 1997 Feb 12;145(2):205-11 [9094050.001]
  • [Cites] J Comp Neurol. 1955 Aug;103(1):105-29 [13263445.001]
  • [Cites] Neuroimage. 2002 Sep;17(1):240-55 [12482081.001]
  • [Cites] Neuroimage. 2001 Aug;14(2):486-500 [11467921.001]
  • [Cites] Mov Disord. 1998 Nov;13(6):958-64 [9827622.001]
  • [Cites] Brain. 2008 Nov;131(Pt 11):2913-27 [18835866.001]
  • [Cites] Mov Disord. 2005 Aug;20(8):1006-13 [15838852.001]
  • [Cites] Magn Reson Med. 1998 Jul;40(1):143-51 [9660564.001]
  • (PMID = 20352395.001).
  • [ISSN] 1473-4230
  • [Journal-full-title] Cerebellum (London, England)
  • [ISO-abbreviation] Cerebellum
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


33. Wüthrich C, Cheng YM, Joseph JT, Kesari S, Beckwith C, Stopa E, Bell JE, Koralnik IJ: Frequent infection of cerebellar granule cell neurons by polyomavirus JC in progressive multifocal leukoencephalopathy. J Neuropathol Exp Neurol; 2009 Jan;68(1):15-25
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Frequent infection of cerebellar granule cell neurons by polyomavirus JC in progressive multifocal leukoencephalopathy.
  • The lesions of PML result from astrocyte and oligodendrocyte infection by the polyomavirus JC (JCV); JCV has also been shown to infect and destroy cerebellar granule cell neurons (GCNs) in 2 human immunodeficiency virus (HIV)-positive patients.
  • To determine the prevalence and pattern of JCV infection in GCNs, we immunostained formalin-fixed paraffin-embedded cerebellar samples from 40 HIV-positive and 3 HIV-negative PML patients for JCV, and glial and neuronal markers.
  • Thus, JCV infection of GCNs is frequent in PML patients and may occur in the absence of cerebellar white matter demyelinating lesions.
  • [MeSH-major] Cerebellum / pathology. JC Virus / pathogenicity. Leukoencephalopathy, Progressive Multifocal / pathology. Leukoencephalopathy, Progressive Multifocal / virology. Neurons / pathology. Neurons / virology
  • [MeSH-minor] 2',3'-Cyclic-Nucleotide Phosphodiesterases / metabolism. Acquired Immunodeficiency Syndrome / complications. Acquired Immunodeficiency Syndrome / pathology. Acquired Immunodeficiency Syndrome / virology. Adult. Aged. Antigens, Viral, Tumor / metabolism. Capsid Proteins / metabolism. Cell Count / methods. Demyelinating Diseases / etiology. Demyelinating Diseases / virology. Female. Humans. Male. Microtubule-Associated Proteins / metabolism. Middle Aged. Phosphopyruvate Hydratase / metabolism. Viral Structural Proteins / metabolism

  • Genetic Alliance. consumer health - Progressive multifocal leukoencephalopathy.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Virol. 2003 Jan;77(2):1347-56 [12502851.001]
  • [Cites] J Neurovirol. 2003;9 Suppl 1:25-31 [12709868.001]
  • [Cites] J Neurovirol. 2003;9 Suppl 1:73-80 [12709876.001]
  • [Cites] Neurology. 2003 Sep 23;61(6):734-5 [14504312.001]
  • [Cites] Neurology. 2003 Sep 23;61(6):775-82 [14504320.001]
  • [Cites] J Neurovirol. 2004 Oct;10(5):315-25 [15385254.001]
  • [Cites] Lancet. 1971 Jun 19;1(7712):1257-60 [4104715.001]
  • [Cites] Prog Clin Biol Res. 1983;105:191-203 [6304757.001]
  • [Cites] Clin Microbiol Rev. 1992 Jan;5(1):49-73 [1310438.001]
  • [Cites] Hum Pathol. 1992 May;23(5):581-6 [1568753.001]
  • [Cites] Neuropathol Appl Neurobiol. 1993 Oct;19(5):398-401 [8278022.001]
  • [Cites] J Neurol Neurosurg Psychiatry. 1994 Aug;57(8):994-7 [8057128.001]
  • [Cites] Neurology. 1998 Jan;50(1):244-51 [9443487.001]
  • [Cites] J Virol. 1998 Dec;72(12):9918-23 [9811728.001]
  • [Cites] Neurology. 1999 Jan 15;52(2):253-60 [9932940.001]
  • [Cites] J Neurosci Res. 2005 Feb 1;79(3):295-302 [15605376.001]
  • [Cites] Ann Neurol. 2005 Apr;57(4):576-80 [15786466.001]
  • [Cites] Int J Surg Pathol. 2005 Oct;13(4):360 [16273193.001]
  • [Cites] Mod Pathol. 2006 Mar;19(3):417-28 [16415794.001]
  • [Cites] J Neurovirol. 2005;11 Suppl 3:16-22 [16540449.001]
  • [Cites] J Neurovirol. 2006 Apr;12(2):116-28 [16798673.001]
  • [Cites] J Gen Virol. 2006 Sep;87(Pt 9):2533-7 [16894191.001]
  • [Cites] Ann Neurol. 2006 Aug;60(2):162-73 [16862584.001]
  • [Cites] Pediatr Neurol. 2007 Mar;36(3):186-9 [17352955.001]
  • [Cites] AJNR Am J Neuroradiol. 1999 Nov-Dec;20(10):1896-906 [10588116.001]
  • [Cites] J Exp Med. 2001 Apr 16;193(8):905-15 [11304551.001]
  • [Cites] Ann Neurol. 2001 May;49(5):636-42 [11357954.001]
  • [Cites] Neuropathol Appl Neurobiol. 2001 Aug;27(4):326-35 [11532163.001]
  • (PMID = 19104450.001).
  • [ISSN] 0022-3069
  • [Journal-full-title] Journal of neuropathology and experimental neurology
  • [ISO-abbreviation] J. Neuropathol. Exp. Neurol.
  • [Language] eng
  • [Grant] United Kingdom / Medical Research Council / / G0500863; United States / NIMH NIH HHS / MH / R24 MH059724; United States / NINDS NIH HHS / NS / K24 NS 060950; United States / NINDS NIH HHS / NS / R0I NS 047029; United States / NINDS NIH HHS / NS / R21 NS051124-02; United States / NIMH NIH HHS / MH / R24 MH059745; United States / NINDS NIH HHS / NS / R24 NS038841; United States / NINDS NIH HHS / NS / R21 NS051124; United States / NINDS NIH HHS / NS / R21 NS051124-01; United States / NINDS NIH HHS / NS / R21 NS 051124; United States / NINDS NIH HHS / NS / R01 NS 041198; United States / NIMH NIH HHS / MH / U01 MH083545; United States / NIAID NIH HHS / AI / P30 AI042853
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, Viral, Tumor; 0 / Capsid Proteins; 0 / MAP2 protein, human; 0 / Microtubule-Associated Proteins; 0 / Viral Structural Proteins; EC 3.1.4.- / 2',3'-Cyclic-Nucleotide Phosphodiesterases; EC 4.2.1.11 / Phosphopyruvate Hydratase
  • [Other-IDs] NLM/ NIHMS87313; NLM/ PMC2637912
  •  go-up   go-down


34. Martin SE, Al-Khatib SM, Turner MS, Douglas-Akinwande AC, Hattab EM: A 41-year-old woman with von Hippel-Lindau and a cerebellar lesion. Brain Pathol; 2010 Mar;20(2):511-4
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A 41-year-old woman with von Hippel-Lindau and a cerebellar lesion.
  • MRI revealed a well-circumscribed, partially cystic cerebellar neoplasm, consistent with hemangioblastoma.
  • The tumor was resected and the diagnosis of hemangioblastoma confirmed.
  • RCC metastatic to a CNS hemangioblastoma is the second most common type of tumor-to-tumor metastasis, which may be due to a number of factors.
  • Proper immunostaining panels are required to clearly identify these cases since both tumor may have similar histology.
  • [MeSH-major] Carcinoma, Renal Cell / secondary. Cerebellar Neoplasms / pathology. Hemangioblastoma / pathology. von Hippel-Lindau Disease / pathology
  • [MeSH-minor] Adult. Brain Neoplasms / diagnosis. Brain Neoplasms / pathology. Cerebellum / pathology. Diagnosis, Differential. Female. Humans. Kidney Neoplasms / pathology. Magnetic Resonance Imaging

  • MedlinePlus Health Information. consumer health - Von Hippel-Lindau Disease.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20438472.001).
  • [ISSN] 1750-3639
  • [Journal-full-title] Brain pathology (Zurich, Switzerland)
  • [ISO-abbreviation] Brain Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Switzerland
  •  go-up   go-down


35. Patrick TA, Giannini C, Ebersold MJ, Link MJ: Iatrogenic cerebellar implantation of a vestibular schwannoma. Case report. J Neurosurg; 2006 Mar;104(3):452-6
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Iatrogenic cerebellar implantation of a vestibular schwannoma. Case report.
  • Metastatic seeding or iatrogenic implantation of numerous types of primary central nervous system tumors, typically along cerebrospinal fluid pathways, is a frequently described albeit rare phenomenon and has never been reported in association with vestibular schwannoma (VS).
  • The authors present a case of inadvertent surgical implantation of VS into the cerebellar hemisphere during resection of a recurrent VS in the cerebellopontine angle and internal auditory canal.
  • Five years later--10 years after initial presentation--follow-up imaging revealed a 1-cm recurrence of the VS and a separate 2.2-cm tumor in the inferior cerebellar parenchyma with surrounding edema.
  • Both tumors were removed without complication by reopening the previous retrosigmoid craniotomy.
  • Histological evaluation of these tumors revealed features typical of VS and similar to those of the tissue obtained from the two prior resections.
  • Given the similarities among these tumors in pathological appearance and mitotic index, the presence of the intraparenchymal cerebellar schwannoma was probably due to intraoperative iatrogenic implantation.
  • [MeSH-major] Cerebellar Neoplasms / etiology. Neuroma, Acoustic / etiology
  • [MeSH-minor] Adult. Cerebellopontine Angle / pathology. Humans. Iatrogenic Disease. Male. Mitotic Index. Neoplasm Recurrence, Local / surgery

  • Genetic Alliance. consumer health - Schwannoma.
  • MedlinePlus Health Information. consumer health - Acoustic Neuroma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16572663.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


36. Fukushima S, Terasaki M, Tajima Y, Shigemori M: Granulocytic sarcoma: an unusual complication of acute promyelocytic leukemia causing cerebellar hemorrhage. Case report. J Neurosurg; 2006 Dec;105(6):912-5
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granulocytic sarcoma: an unusual complication of acute promyelocytic leukemia causing cerebellar hemorrhage. Case report.
  • Granulocytic sarcomas are rare tumors that occur primarily in patients with acute myelogenous leukemia or other myeloproliferative disorders, are seldom seen in patients with acute promyelocytic leukemia (APL), and have never been reported to occur in the cerebellum.
  • The authors describe the case of a patient with APL who harbored a hemorrhagic granulocytic sarcoma in the cerebellum.
  • This 39-year-old woman presented with cerebellar ataxia.
  • Magnetic resonance images revealed an intraaxial tumor in the cerebellum.
  • Results of histopathological studies and immunohistochemical staining of the cerebellar tumor confirmed a granulocytic sarcoma.
  • This is the first report to document a granulocytic sarcoma in the cerebellum as the primary presentation in a patient with APL and abnormal coagulation.
  • [MeSH-major] Cerebellar Neoplasms / etiology. Cerebral Hemorrhage / etiology. Leukemia, Promyelocytic, Acute / complications. Sarcoma, Myeloid / etiology
  • [MeSH-minor] Adult. Bone Marrow / pathology. Cerebellar Ataxia / etiology. Cerebellum / pathology. Chimera / genetics. Female. Gene Fusion / genetics. Granulocyte Precursor Cells / pathology. Humans. Inclusion Bodies / pathology. Karyotyping. Magnetic Resonance Imaging. Receptors, Retinoic Acid / genetics

  • Genetic Alliance. consumer health - Acute Promyelocytic Leukemia.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17405265.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, Retinoic Acid; 0 / retinoic acid receptor alpha
  •  go-up   go-down


37. Northcott PA, Fernandez-L A, Hagan JP, Ellison DW, Grajkowska W, Gillespie Y, Grundy R, Van Meter T, Rutka JT, Croce CM, Kenney AM, Taylor MD: The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors. Cancer Res; 2009 Apr 15;69(8):3249-55
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors.
  • Medulloblastoma is the most common malignant pediatric brain tumor, and mechanisms underlying its development are poorly understood.
  • Consistent with its regulation by Shh, we observed that Shh treatment of primary cerebellar granule neuron precursors (CGNP), proposed cells of origin for the Shh-associated medulloblastomas, resulted in increased miR-17/92 expression.

  • COS Scholar Universe. author profiles.
  • KOMP Repository. gene/protein/disease-specific - KOMP Repository (subscription/membership/fee required).
  • Mouse Genome Informatics (MGI). Mouse Genome Informatics (MGI) .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Nature. 2002 Jan 24;415(6870):436-42 [11807556.001]
  • [Cites] Cancer Cell. 2002 Jul;2(1):7-8 [12150819.001]
  • [Cites] Development. 2003 Jan;130(1):15-28 [12441288.001]
  • [Cites] Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7331-6 [12777630.001]
  • [Cites] Development. 2004 Jan;131(1):217-28 [14660435.001]
  • [Cites] Nature. 2005 Jun 9;435(7043):828-33 [15944707.001]
  • [Cites] Nature. 2005 Jun 9;435(7043):839-43 [15944709.001]
  • [Cites] J Neurobiol. 2005 Sep 15;64(4):458-75 [16041741.001]
  • [Cites] Nucleic Acids Res. 2005;33(20):e179 [16314309.001]
  • [Cites] J Clin Oncol. 2006 Apr 20;24(12):1924-31 [16567768.001]
  • [Cites] Nat Rev Cancer. 2006 Nov;6(11):857-66 [17060945.001]
  • [Cites] Int J Cancer. 2008 Feb 1;122(3):699-704 [17943719.001]
  • [Cites] Nat Immunol. 2008 Apr;9(4):405-14 [18327259.001]
  • [Cites] Cell. 2008 Apr 18;133(2):217-22 [18423194.001]
  • [Cites] Blood. 2009 Jan 8;113(2):396-402 [18941111.001]
  • [Cites] Nat Genet. 2009 Apr;41(4):465-72 [19270706.001]
  • [Cites] PLoS One. 2008;3(8):e3088 [18769486.001]
  • (PMID = 19351822.001).
  • [ISSN] 1538-7445
  • [Journal-full-title] Cancer research
  • [ISO-abbreviation] Cancer Res.
  • [Language] ENG
  • [Grant] United States / NINDS NIH HHS / NS / NS061070-01; United States / NINDS NIH HHS / NS / R01 NS061070; United States / NINDS NIH HHS / NS / R01 NS061070-01; United States / NINDS NIH HHS / NS / R01NS061070
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Hedgehog Proteins; 0 / MIRN17 microRNA, human; 0 / MicroRNAs; 0 / Proto-Oncogene Proteins c-myc; 0 / SHH protein, human
  • [Other-IDs] NLM/ NIHMS100132; NLM/ PMC2836891
  •  go-up   go-down


38. Sherman JH, Sheehan JP, Elias WJ, Jane JA Sr: Cerebellar mutism in adults after posterior fossa surgery: a report of 2 cases. Surg Neurol; 2005 May;63(5):476-9
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebellar mutism in adults after posterior fossa surgery: a report of 2 cases.
  • BACKGROUND: Mutism has been associated with injury to midline cerebellar structures secondary to degenerative disease, tumors, hemorrhage, or surgery.
  • Typically, cerebellar mutism syndrome (CMS) has been seen in children and only rarely described in adults after surgery of the posterior fossa.
  • CASE DESCRIPTION: The authors report on 2 patients each of whom developed cerebellar mutism after tumor resection using a posterior fossa approach.
  • The first patient underwent gross total resection of a pineal region tumor via a supracerebellar approach.
  • The second patient underwent posterior fossa decompression for a left cerebellar hemispheric renal cell carcinoma metastasis with adjacent hemorrhage.
  • One patient displayed a variant of cerebellar mutism with severe ataxic dysarthria without complete absence of speech, whereas the other demonstrated frank mutism.
  • CONCLUSION: It is paramount that neurosurgeons be aware of cerebellar mutism with regard to its very rare occurrence in adults, its time of onset, and typical self-limiting course.
  • [MeSH-major] Brain Neoplasms / surgery. Carcinoma, Renal Cell / surgery. Cerebellum / surgery. Cranial Fossa, Posterior / surgery. Dermoid Cyst / surgery. Mutism / etiology. Neurosurgical Procedures / adverse effects
  • [MeSH-minor] Adult. Cerebellar Neoplasms / physiopathology. Cerebellar Neoplasms / secondary. Cerebellar Neoplasms / surgery. Decompression, Surgical / adverse effects. Female. Humans. Kidney Neoplasms / pathology. Magnetic Resonance Imaging. Middle Aged. Neoplasm Recurrence, Local. Neoplasm, Residual. Pinealoma / pathology. Pinealoma / surgery. Postoperative Complications / etiology. Postoperative Complications / pathology. Radiosurgery. Radiotherapy. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Surg Neurol. 2006 Apr;65(4):424 [16531220.001]
  • (PMID = 15883080.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


39. Miyazawa T, Aida S, Shima K: Hemorrhagic cerebellar anaplastic glioma appearing 12 years after prophylactic cranial radiotherapy for acute lymphocytic leukemia. Neurol Med Chir (Tokyo); 2008 Mar;48(3):126-30
Genetic Alliance. consumer health - Glioma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hemorrhagic cerebellar anaplastic glioma appearing 12 years after prophylactic cranial radiotherapy for acute lymphocytic leukemia.
  • A radiation-induced cerebellar glioma is extremely rare, and the etiology of such a tumor is unknown.
  • We report a rare case of hemorrhagic cerebellar anaplastic glioma occurring 12 years after prophylactic cranial radiotherapy for acute lymphocytic leukemia.
  • We discuss the etiologies of the radiation-induced hemorrhagic cerebellar glioma as a secondary malignancy after radiotherapy.
  • [MeSH-major] Cerebellar Neoplasms / etiology. Glioma / etiology. Intracranial Hemorrhages / etiology. Neoplasms, Radiation-Induced / etiology. Neoplasms, Second Primary / etiology. Precursor Cell Lymphoblastic Leukemia-Lymphoma / radiotherapy
  • [MeSH-minor] Adult. Anaplasia / etiology. Anaplasia / pathology. Humans. Male. Radiotherapy / adverse effects. Time Factors

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18362460.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


40. Cui L, Pierce D, Light KE, Melchert RB, Fu Q, Kumar KS, Hauer-Jensen M: Sublethal total body irradiation leads to early cerebellar damage and oxidative stress. Curr Neurovasc Res; 2010 May;7(2):125-35
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sublethal total body irradiation leads to early cerebellar damage and oxidative stress.
  • The present study aimed at identifying early damage index in the cerebellum following total body irradiation (TBI).
  • Adult male CD2F1 mice (n=18) with or without TBI challenge (8.5 Gy irradiation) were assessed for histology and expression of selected immunohistochemical markers including malondiadehyde (MDA), 8-hydroxy-2'-deoxyguanosine (8-OHdG), protein 53 (p53), vascular endothelial growth factor receptor 2 (VEGF-R2), CD45, calbindin D-28k (CB- 28) and vesicular glutamate transport-2 (VGLUT2) in cerebellar folia II to IV.
  • Substantial damage to the cerebellum can be detectable as early as 1- 3.5 days in adult animals following sublethal TBI.

  • Hazardous Substances Data Bank. MALONALDEHYDE .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Cancer Res. 1993 Dec 1;53(23):5822-7 [7694795.001]
  • [Cites] Ann Neurol. 1995 Jun;37(6):810-4 [7778856.001]
  • [Cites] J Neurosci. 1995 Aug;15(8):5851-7 [7643225.001]
  • [Cites] Biochem Pharmacol. 1998 Jun 15;55(12):2043-6 [9714326.001]
  • [Cites] Eur J Neurosci. 2000 Mar;12(3):945-54 [10762324.001]
  • [Cites] Oncogene. 2001 Oct 25;20(48):7085-95 [11704832.001]
  • [Cites] Neurol Res. 2001 Dec;23(8):869-74 [11760880.001]
  • [Cites] J Nutr. 2003 Jan;133(1):51-6 [12514266.001]
  • [Cites] Eur J Neurosci. 2003 Jun;17(12):2563-72 [12823463.001]
  • [Cites] Circ Res. 2003 Aug 22;93(4):354-63 [12893742.001]
  • [Cites] J Comp Neurol. 1977 Jan 1;171(1):39-50 [830670.001]
  • [Cites] Health Phys. 1979 Sep;37(3):400-1 [511570.001]
  • [Cites] Experientia. 1984 Sep 15;40(9):910-21 [6205895.001]
  • [Cites] J Neurol Sci. 1987 Mar;78(1):93-109 [2437253.001]
  • [Cites] Annu Rev Biochem. 1987;56:395-433 [3304139.001]
  • [Cites] J Neurosci. 1988 Dec;8(12):4780-9 [3199205.001]
  • [Cites] Dev Biol. 1989 May;133(1):67-76 [2707487.001]
  • [Cites] Bibl Nutr Dieta. 1989;(43):288-96 [2658964.001]
  • [Cites] EMBO J. 1990 Jan;9(1):61-7 [2153079.001]
  • [Cites] Neuroscience. 1990;35(2):375-475 [2199841.001]
  • [Cites] Nervenarzt. 1991 Apr;62(4):221-5 [1857456.001]
  • [Cites] Cell Tissue Res. 1993 Feb;271(2):181-208 [8453652.001]
  • [Cites] JPEN J Parenter Enteral Nutr. 1999 Jan-Feb;23(1):19-23 [9888413.001]
  • [Cites] J Biol Chem. 1999 Jun 25;274(26):18393-400 [10373445.001]
  • [Cites] Neurosci Lett. 2006 Jul 10;402(1-2):86-91 [16632199.001]
  • [Cites] Mol Hum Reprod. 2006 Jun;12(6):367-75 [16648151.001]
  • [Cites] Behav Brain Res. 2007 Feb 12;177(1):7-14 [17145083.001]
  • [Cites] Cell Biol Toxicol. 2007 Mar;23(2):129-37 [17094020.001]
  • [Cites] Int J Cancer. 2007 May 1;120(9):1899-908 [17230507.001]
  • [Cites] J Exp Biol. 2007 Apr;210(Pt 8):1455-62 [17401128.001]
  • [Cites] Eur J Neurosci. 2007 Mar;25(5):1349-56 [17425561.001]
  • [Cites] Neurotoxicology. 2007 May;28(3):555-61 [17267041.001]
  • [Cites] Cell Signal. 2007 Oct;19(10):2003-12 [17658244.001]
  • [Cites] Neurosci Biobehav Rev. 2007;31(8):1101-13 [17599406.001]
  • [Cites] Behav Brain Res. 2008 Mar 5;187(2):387-95 [18006086.001]
  • [Cites] J Pineal Res. 2008 Mar;44(2):189-96 [18289171.001]
  • [Cites] J Pathol. 2008 Apr;214(5):610-6 [18266203.001]
  • [Cites] Epilepsy Res. 2008 May;79(2-3):213-23 [18394865.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2008 Nov 1;72(3):918-26 [19014781.001]
  • [Cites] Stroke. 2009 Jan;40(1):270-7 [18948613.001]
  • [Cites] Neurobiol Aging. 2009 Jun;30(6):903-9 [17976863.001]
  • [Cites] Chem Biol Interact. 2009 Jun 15;180(1):31-8 [19428343.001]
  • [Cites] Am J Cardiol. 2009 Jun 1;103(11):1500-5 [19463506.001]
  • [Cites] Glia. 2009 Sep;57(12):1296-305 [19191347.001]
  • [Cites] Circ Cardiovasc Imaging. 2010 Jan;3(1):77-85 [19920031.001]
  • [Cites] Cell Mol Neurobiol. 2010 Jan;30(1):1-12 [19533334.001]
  • [Cites] J Neuropathol Exp Neurol. 2008 Jul;67(7):711-9 [18596542.001]
  • (PMID = 20334614.001).
  • [ISSN] 1875-5739
  • [Journal-full-title] Current neurovascular research
  • [ISO-abbreviation] Curr Neurovasc Res
  • [Language] ENG
  • [Grant] United States / NIEHS NIH HHS / ES / 27302C0028; United States / NIAID NIH HHS / AI / U19 AI067798; United States / NIAID NIH HHS / AI / AI67798
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Calbindins; 0 / S100 Calcium Binding Protein G; 0 / Slc17a6 protein, rat; 0 / Tumor Suppressor Protein p53; 0 / Vesicular Glutamate Transport Protein 2; 4Y8F71G49Q / Malondialdehyde; 88847-89-6 / 8-oxo-7-hydrodeoxyguanosine; EC 2.7.10.1 / Vascular Endothelial Growth Factor Receptor-2; EC 3.1.3.48 / Antigens, CD45; G9481N71RO / Deoxyguanosine
  • [Other-IDs] NLM/ NIHMS461034; NLM/ PMC3637794
  •  go-up   go-down


41. Padovani L, André N, Carrie C, Muracciole X: [Childhood and adult medulloblastoma: what difference?]. Cancer Radiother; 2009 Oct;13(6-7):530-5
Genetic Alliance. consumer health - Medulloblastoma, childhood.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Childhood and adult medulloblastoma: what difference?].
  • Medulloblastoma is the most frequent childhood brain tumor (30%) but account only for less than 1% of adult brain tumor.
  • Due to the rarety in adult population, no prospective studies and few data about late effects are available.
  • Adult medulloblastoma is a therapeutic challenge and their therapeutic strategies are similar to pediatric protocols.
  • In order to improve the understanding of adult disease and to homogenize the treatment, National Cancer Institute (INCa) stimulated the creation of web conference to discuss each case prospectively and to propose a protocol of treatment.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Medulloblastoma / pathology
  • [MeSH-minor] Adult. Age Factors. Antineoplastic Agents / adverse effects. Antineoplastic Agents / therapeutic use. Brain Neoplasms / epidemiology. Child. Cognition Disorders / epidemiology. Cognition Disorders / etiology. Combined Modality Therapy. France / epidemiology. Humans. Incidence. Molecular Biology / methods. Radiotherapy / adverse effects. Radiotherapy / methods. Surgical Procedures, Operative

  • Genetic Alliance. consumer health - Medulloblastoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19713143.001).
  • [ISSN] 1769-6658
  • [Journal-full-title] Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
  • [ISO-abbreviation] Cancer Radiother
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  •  go-up   go-down


42. Rubello D, Vitaliani R, Rigoni MT, Rampin L, Giometto B, Casara D, Zonzin GC, Zavagno G, Capirci C, Shapiro B, Muzzio PC: A rare case of paraneoplastic cerebellar degeneration discovered by whole-body F-18 FDG PET. Clin Nucl Med; 2005 Oct;30(10):704-6
MedlinePlus Health Information. consumer health - CT Scans.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A rare case of paraneoplastic cerebellar degeneration discovered by whole-body F-18 FDG PET.
  • A rare case of paraneoplastic cerebellar degeneration (PCD) in a 36-year-old woman is reported.
  • No tumor was found until April 2003; repeated CT scan, ultrasound, and mammographic examinations were negative.
  • In the reported case, F-18 FDG PET played a crucial role in detecting the unknown primary tumor in a young patient with PCD.
  • [MeSH-major] Breast Neoplasms / complications. Breast Neoplasms / diagnosis. Fluorodeoxyglucose F18. Paraneoplastic Cerebellar Degeneration / diagnosis. Paraneoplastic Cerebellar Degeneration / etiology. Positron-Emission Tomography / methods. Tomography, X-Ray Computed / methods. Whole Body Imaging / methods
  • [MeSH-minor] Adult. Female. Humans. Radiopharmaceuticals. Rare Diseases / diagnosis


43. Kajimoto K, Oku N, Kimura Y, Kato H, Tanaka MR, Kanai Y, Kitagawa K, Maruno M, Yoshimine T, Hori M, Hatazawa J: Crossed cerebellar diaschisis: a positron emission tomography study with L-[methyl-11C]methionine and 2-deoxy-2-[18F]fluoro-D-glucose. Ann Nucl Med; 2007 Feb;21(2):109-13
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Crossed cerebellar diaschisis: a positron emission tomography study with L-[methyl-11C]methionine and 2-deoxy-2-[18F]fluoro-D-glucose.
  • OBJECTIVE: Crossed cerebellar diaschisis (CCD) is defined as a depression of blood flow and oxidative metabolism of glucose in the cerebellum contralateral to a supratentorial brain lesion, as detected with positron emission tomography (PET) and single photon emission computed tomography.
  • METHODS: In 12 patients with a unilateral supratentorial brain tumor, we evaluated the uptake of 2-deoxy-2-[18F]fluoro-D-glucose (FDG) and MET in the cerebellar hemispheres by means of PET.
  • Asymmetry index (AI) was defined as a difference in the average count between the ipsilateral and contralateral cerebellar hemispheres divided by the average count in both cerebellar hemispheres.
  • CONCLUSIONS: Different from glucose metabolism, cerebellar MET uptake was not affected in CCD.
  • The present study may indicate that cerebellar MET uptake is independent of suppression of cerebellar neuronal activity.
  • [MeSH-major] Cerebellar Diseases / metabolism. Cerebellar Diseases / radionuclide imaging. Fluorodeoxyglucose F18 / pharmacokinetics. Methionine / analogs & derivatives. Positron-Emission Tomography / methods
  • [MeSH-minor] Adult. Aged. Brain Neoplasms / metabolism. Brain Neoplasms / radionuclide imaging. Cerebellum / blood supply. Cerebellum / metabolism. Cerebellum / radionuclide imaging. Female. Humans. Male. Middle Aged. Radiopharmaceuticals / pharmacokinetics. Reproducibility of Results. Sensitivity and Specificity

  • MedlinePlus Health Information. consumer health - Cerebellar Disorders.
  • Hazardous Substances Data Bank. (L)-Methionine .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17424977.001).
  • [ISSN] 0914-7187
  • [Journal-full-title] Annals of nuclear medicine
  • [ISO-abbreviation] Ann Nucl Med
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18; AE28F7PNPL / Methionine; BN630929UL / methionine methyl ester
  •  go-up   go-down


44. Selek U, Zorlu F, Hurmuz P, Cengiz M, Turker A, Soylemezoglu F, Gurkaynak M: Craniospinal radiotherapy in adult medulloblastoma. Strahlenther Onkol; 2007 May;183(5):236-40
Genetic Alliance. consumer health - Medulloblastoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Craniospinal radiotherapy in adult medulloblastoma.
  • PURPOSE: To evaluate the outcome and prognostic factors of adult patients with medulloblastoma.
  • PATIENTS AND METHODS: 26 adult medulloblastoma patients with a median age of 27 were subjected to craniospinal radiotherapy.
  • Patient characteristics, treatment factors and tumor characteristics failed to show any significance in univariate analysis.
  • CONCLUSION: Yet, the current standard of care seems to remain craniospinal irradiation after maximal surgical resection of the primary neoplasm without clear indications for adjuvant chemotherapy.
  • [MeSH-major] Cerebellar Neoplasms / radiotherapy. Cranial Irradiation. Medulloblastoma / radiotherapy. Spine / radiation effects
  • [MeSH-minor] Adolescent. Adult. Cohort Studies. Combined Modality Therapy. Disease-Free Survival. Female. Humans. Male. Prognosis. Radiotherapy Dosage. Radiotherapy, Adjuvant. Retrospective Studies. Survival Rate. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17497094.001).
  • [ISSN] 0179-7158
  • [Journal-full-title] Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]
  • [ISO-abbreviation] Strahlenther Onkol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


45. Taraszewska A, Czernicki Z, Andrychowski J: Hemosiderin pigmentation of tumour cells in cerebellar pilocytic astrocytoma associated with post-traumatic hemorrhage in adults. Folia Neuropathol; 2005;43(3):172-7
Genetic Alliance. consumer health - Pilocytic astrocytoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hemosiderin pigmentation of tumour cells in cerebellar pilocytic astrocytoma associated with post-traumatic hemorrhage in adults.
  • We report an unusual case of pigmented cerebellar pilocytic astrocytoma presenting with posttraumatic hemorrhage in a 38-year-old man with no history related to the tumor.
  • CT and MRI examination after head injury demonstrated unexpectedly the cystic lesion of 2 cm in diameter in the region of the right cerebellar hemisphere and vermis.
  • In the literature, the examples of neuroepithelial tumors with hemosiderin pigmentation of tumor cells have been rarely documented.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16245213.001).
  • [ISSN] 1641-4640
  • [Journal-full-title] Folia neuropathologica
  • [ISO-abbreviation] Folia Neuropathol
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 9011-92-1 / Hemosiderin
  •  go-up   go-down


46. Wehrle R, Camand E, Chedotal A, Sotelo C, Dusart I: Expression of netrin-1, slit-1 and slit-3 but not of slit-2 after cerebellar and spinal cord lesions. Eur J Neurosci; 2005 Nov;22(9):2134-44
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of netrin-1, slit-1 and slit-3 but not of slit-2 after cerebellar and spinal cord lesions.
  • To determine whether members of the Netrin-1 and Slit families and their receptors are expressed after central nervous system (CNS) injury, we performed in situ hybridization for netrin-1, slit-1, 2 and 3, and their receptors (dcc, unc5h-1, 2 and 3, robo-1, 2 and 3) 8 days, 2-3 months and 12-18 months after traumatic lesions of rat cerebellum.
  • By contrast, cells expressing netrin-1, slit-1 and slit-3, unc5h-1, 2 and 3, and robo-1, 2 and 3 (rig-1) could be detected at the cerebellar lesion site as soon as 8 days after injury.
  • Thus, Netrin-1, Slits and their receptors may contribute to the regenerative failure of axons in the adult CNS by inhibiting axon outgrowth or by participating in the formation of the CNS scar.
  • [MeSH-major] Cerebellum / metabolism. Membrane Proteins / metabolism. Nerve Growth Factors / metabolism. Nerve Tissue Proteins / metabolism. Spinal Cord Injuries / metabolism. Tumor Suppressor Proteins / metabolism

  • MedlinePlus Health Information. consumer health - Spinal Cord Injuries.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16262652.001).
  • [ISSN] 0953-816X
  • [Journal-full-title] The European journal of neuroscience
  • [ISO-abbreviation] Eur. J. Neurosci.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Intercellular Signaling Peptides and Proteins; 0 / Membrane Proteins; 0 / Nerve Growth Factors; 0 / Nerve Tissue Proteins; 0 / Receptors, Cell Surface; 0 / Receptors, Immunologic; 0 / Slit homolog 2 protein; 0 / Slit1 protein, rat; 0 / Slit3 protein, rat; 0 / Tumor Suppressor Proteins; 0 / roundabout protein; 158651-98-0 / netrin-1
  •  go-up   go-down


47. Oztürk S, Soyluk O, Görçin S, Alişir S, Güven D, Türkmen A, Sever MS: A rare post-transplant malignancy, cerebellar hemangioblastoma: a case report. J Nephrol; 2005 Nov-Dec;18(6):781-2
MedlinePlus Health Information. consumer health - Kidney Transplantation.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A rare post-transplant malignancy, cerebellar hemangioblastoma: a case report.
  • Hemangioblastoma (HB) is especially prevalent in the cerebellum.
  • On cranial magnetic resonance imaging (MRI), a mass lesion in the right cerebellar hemisphere was observed, 3 x 3 x 3 cm in size, which was pushing against the fourth ventricle, and the right cerebellar peduncle.
  • The pathological diagnosis was cerebellar hemangioblastoma.
  • DISCUSSION: HB causes 2% of all intracranial tumors in the general population.
  • The treatment is surgical excision of the tumor, as in this case.
  • CONCLUSION: When cerebellar symptoms occur or a cerebellar mass lesion is detected in an organ recipient, HB should be considered in the differential diagnosis.
  • [MeSH-major] Cerebellar Neoplasms / etiology. Hemangioblastoma / etiology. Kidney Transplantation / adverse effects
  • [MeSH-minor] Adult. Craniotomy. Follow-Up Studies. Humans. Kidney Failure, Chronic / surgery. Magnetic Resonance Imaging. Male

  • Genetic Alliance. consumer health - Hemangioblastoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16358240.001).
  • [ISSN] 1121-8428
  • [Journal-full-title] Journal of nephrology
  • [ISO-abbreviation] J. Nephrol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


48. Kamide T, Nakada M, Hayashi Y, Suzuki T, Hayashi Y, Uchiyama N, Kijima T, Hamada J: Radiation-induced cerebellar high-grade glioma accompanied by meningioma and cavernoma 29 years after the treatment of medulloblastoma: a case report. J Neurooncol; 2010 Nov;100(2):299-303
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radiation-induced cerebellar high-grade glioma accompanied by meningioma and cavernoma 29 years after the treatment of medulloblastoma: a case report.
  • Here, we report the case of a patient with cerebellar high-grade glioma that developed after the patient underwent treatment for medulloblastoma.
  • Magnetic resonance image showed a cerebellar tumor with multiple cavernomas and two lesions that were suspected to be meningiomas.
  • The cerebellar tumor was surgically removed.
  • According to pathological examination, the tumor was a high-grade glioma that was positive for methylated O-6-methylguanine-DNA methyltransferase promoter.
  • In the past, he had received radiotherapy at the age of 5, after which he was operated for desmoplastic medulloblastoma in his right cerebellar hemisphere.
  • To our knowledge, this is the first case of radiation-induced double intracranial tumors accompanied by symptomatic cavernoma.
  • [MeSH-major] Cerebellar Neoplasms / etiology. Glioma / etiology. Hemangioma, Cavernous, Central Nervous System / etiology. Meningioma / etiology. Meningioma / pathology. Neoplasms, Radiation-Induced / pathology
  • [MeSH-minor] Adult. DNA Methylation. DNA Modification Methylases / genetics. DNA Repair Enzymes / genetics. Humans. Male. Medulloblastoma / radiotherapy. Meningeal Neoplasms / etiology. Meningeal Neoplasms / genetics. Meningeal Neoplasms / pathology. Polymerase Chain Reaction. Promoter Regions, Genetic / genetics. Tumor Suppressor Proteins / genetics

  • Genetic Alliance. consumer health - Glioma.
  • Genetic Alliance. consumer health - Medulloblastoma.
  • Genetic Alliance. consumer health - Meningioma.
  • Genetic Alliance. consumer health - Radiation induced meningioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Neuropathology. 2008 Dec;28(6):633-9 [18384514.001]
  • [Cites] J Clin Oncol. 2008 Sep 1;26(25):4189-99 [18757334.001]
  • [Cites] Proc Natl Acad Sci U S A. 1996 Sep 3;93(18):9821-6 [8790415.001]
  • [Cites] J Neurosurg. 2006 Feb;104(2 Suppl):103-7 [16506497.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2000 Aug 1;48(1):65-73 [10924973.001]
  • [Cites] J Neurooncol. 2008 Sep;89(2):169-77 [18566750.001]
  • [Cites] J Cell Biol. 2008 Nov 3;183(3):385-91 [18955550.001]
  • [Cites] Neuro Oncol. 2008 Dec;10(6):1040-60 [18676356.001]
  • [Cites] Lancet Oncol. 2006 May;7(5):392-401 [16648043.001]
  • [Cites] Childs Nerv Syst. 2009 Jun;25(6):713-8 [19247675.001]
  • [Cites] Neurol Med Chir (Tokyo). 2007 May;47(5):210-3; discussion 213-4 [17527047.001]
  • [Cites] Cancer. 1998 Jan 1;82(1):8-34 [9428476.001]
  • [Cites] Cancer. 2009 Aug 1;115(15):3512-8 [19514084.001]
  • [Cites] Cancer Res. 2000 Nov 1;60(21):5954-8 [11085511.001]
  • [Cites] Neurol Med Chir (Tokyo). 2007 Aug;47(8):341-9; discussion 350 [17721049.001]
  • [Cites] J Neurooncol. 2008 Jul;88(3):315-20 [18373066.001]
  • [Cites] Clin Cancer Res. 2004 Mar 15;10 (6):1871-4 [15041700.001]
  • [Cites] Neurol Med Chir (Tokyo). 2007 Feb;47(2):53-7; discussion 57 [17317941.001]
  • [Cites] J Neurosurg. 2007 May;106(5 Suppl):379-83 [17566205.001]
  • [Cites] Lancet Neurol. 2007 Dec;6(12):1073-85 [18031705.001]
  • [Cites] Childs Nerv Syst. 2008 Jul;24(7):793-805 [18392837.001]
  • [Cites] J Clin Neurosci. 2009 Aug;16(8):1086-8 [19409792.001]
  • [Cites] Clin Neurol Neurosurg. 1998 Mar;100(1):56-9 [9637208.001]
  • [Cites] N Engl J Med. 2005 Mar 10;352(10 ):997-1003 [15758010.001]
  • [Cites] J Neurosurg. 2000 Dec;93(6):1003-13 [11117842.001]
  • [Cites] Cancer. 2002 Jun 15;94(12):3285-91 [12115362.001]
  • [Cites] AJNR Am J Neuroradiol. 2005 May;26(5):1158-62 [15891176.001]
  • (PMID = 20354758.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Tumor Suppressor Proteins; EC 2.1.1.- / DNA Modification Methylases; EC 2.1.1.63 / MGMT protein, human; EC 6.5.1.- / DNA Repair Enzymes
  •  go-up   go-down


49. Miwa T, Hirose Y, Sasaki H, Ikeda E, Yoshida K, Kawase T: Genetic characterization of adult infratentorial gliomas. J Neurooncol; 2009 Feb;91(3):251-5
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Genetic characterization of adult infratentorial gliomas.
  • Adult infratentorial gliomas are rare and have not been well studied.
  • We therefore conducted genetic analysis of those tumors to see if there was any characteristic that could be relevant in clinical management and understanding of tumorigenesis.
  • Nineteen adult infratentorial gliomas were analyzed for chromosomal aberration by comparative genomic hybridization, and for expression of p53 and epidermal growth factor receptor (EGFR) by immunohistochemistry.
  • The most frequent chromosomal aberration was the gain of 7p, and five of the seven cerebellar or fourth ventricle malignant gliomas had that aberration.
  • However, the gain of 7q, the characteristic abnormality of supratentorial astrocytomas commonly associated with the gaining of 7p, was observed only in 1 of 11 adult infratentorial astrocytic tumors.
  • Our findings might suggest the presence of distinct tumorigenic pathway in adult infratentorial gliomas.
  • [MeSH-major] Brain Neoplasms / genetics. Frontal Lobe / pathology. Glioma / genetics. Receptor, Epidermal Growth Factor / genetics. Tumor Suppressor Protein p53 / genetics
  • [MeSH-minor] Adult. Aged. Chromosome Aberrations. Chromosome Deletion. Chromosomes, Human, Pair 1 / genetics. Chromosomes, Human, Pair 19 / genetics. Chromosomes, Human, Pair 7 / genetics. Comparative Genomic Hybridization. Female. Humans. Loss of Heterozygosity. Male. Middle Aged. Young Adult

  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Keio J Med. 2006 Jun;55(2):52-8 [16823260.001]
  • [Cites] Cancer Res. 2001 Sep 15;61(18):6713-5 [11559541.001]
  • [Cites] Am J Pathol. 2001 Jul;159(1):359-67 [11438483.001]
  • [Cites] J Neurooncol. 2005 Sep;74(2):151-4 [16193385.001]
  • [Cites] Cancer Genet Cytogenet. 2003 Apr 1;142(1):1-7 [12660025.001]
  • [Cites] Am J Pathol. 2001 Mar;158(3):1137-43 [11238062.001]
  • [Cites] J Natl Cancer Inst. 1998 Oct 7;90(19):1473-9 [9776413.001]
  • [Cites] Am J Pathol. 2002 Jul;161(1):313-9 [12107116.001]
  • [Cites] J Neuropathol Exp Neurol. 1996 Jul;55(7):822-31 [8965097.001]
  • [Cites] J Neurooncol. 1998 Feb;36(3):247-57 [9524103.001]
  • [Cites] J Mol Diagn. 2001 May;3(2):62-7 [11333301.001]
  • (PMID = 18941867.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Tumor Suppressor Protein p53; EC 2.7.10.1 / Receptor, Epidermal Growth Factor
  •  go-up   go-down


50. Ito-Ishida A, Miura E, Emi K, Matsuda K, Iijima T, Kondo T, Kohda K, Watanabe M, Yuzaki M: Cbln1 regulates rapid formation and maintenance of excitatory synapses in mature cerebellar Purkinje cells in vitro and in vivo. J Neurosci; 2008 Jun 4;28(23):5920-30
Mouse Genome Informatics (MGI). Mouse Genome Informatics (MGI) .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cbln1 regulates rapid formation and maintenance of excitatory synapses in mature cerebellar Purkinje cells in vitro and in vivo.
  • Cbln1, which belongs to the C1q/tumor necrosis factor superfamily, is the most recently identified protein involved in synapse formation in the mammalian CNS.
  • In the cerebellum, Cbln1 is predominantly produced and secreted from granule cells; cbln1-null mice show ataxia and a severe reduction in the number of synapses between Purkinje cells and parallel fibers (PFs), the axon bundle of granule cells.
  • Cbln1 also rapidly induced electrophysiologically functional and ultrastructurally normal PF synapses in acutely prepared cbln1-null cerebellar slices.
  • Furthermore, a single injection of recombinant Cbln1 rescued severe ataxia in adult cbln1-null mice in vivo by completely, but transiently, restoring PF synapses.
  • Therefore, Cbln1 is a unique synapse organizer that is required not only for the normal development of PF-Purkinje cell synapses but also for their maintenance in the mature cerebellum both in vitro and in vivo.
  • Furthermore, our results indicate that Cbln1 can also rapidly organize new synapses in adult cerebellum, implying its therapeutic potential for cerebellar ataxic disorders.
  • [MeSH-minor] Age Factors. Animals. Cell Line. Cells, Cultured. Cerebellum / growth & development. Cerebellum / ultrastructure. Mice. Mice, Knockout

  • KOMP Repository. gene/protein/disease-specific - KOMP Repository (subscription/membership/fee required).
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18524896.001).
  • [ISSN] 1529-2401
  • [Journal-full-title] The Journal of neuroscience : the official journal of the Society for Neuroscience
  • [ISO-abbreviation] J. Neurosci.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cbln1 protein, mouse; 0 / Nerve Tissue Proteins; 0 / Protein Precursors
  •  go-up   go-down


51. Weber DC, Miller RC, Villà S, Hanssens P, Baumert BG, Castadot P, Varlet P, Abacioglu U, Igdem S, Szutowicz E, Nishioka H, Hofer S, Rutz HP, Ozsahin M, Taghian A, Mirimanoff RO: Outcome and prognostic factors in cerebellar glioblastoma multiforme in adults: a retrospective study from the Rare Cancer Network. Int J Radiat Oncol Biol Phys; 2006 Sep 1;66(1):179-86
MedlinePlus Health Information. consumer health - Rare Diseases.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Outcome and prognostic factors in cerebellar glioblastoma multiforme in adults: a retrospective study from the Rare Cancer Network.
  • PURPOSE: The aim of this study was to assess the outcome in patients with cerebellar glioblastoma (GBM) treated in 15 institutions of the Rare Cancer Network.
  • METHODS AND MATERIALS: Data from a series of 45 adult patients with cerebellar GBM were collected in a retrospective multicenter study.
  • RESULTS: The 1-year and 2-year actuarial overall survival rate was 37.8% and 14.7%, respectively, and was significantly influenced by salvage treatment (p = 0.048), tumor volume (p = 0.044), extent of neurosurgical resection (p = 0.019), brainstem invasion (p = 0.0013), additional treatment after surgery (p < 0.001), and completion of the initial treatment (p < 0.001) on univariate analysis.
  • [MeSH-major] Cerebellar Neoplasms / radiotherapy. Glioblastoma / radiotherapy. Rare Diseases / radiotherapy
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Combined Modality Therapy / methods. Disease Progression. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Prognosis. Retrospective Studies. Survival Rate. Treatment Outcome

  • Genetic Alliance. consumer health - Glioblastoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16814953.001).
  • [ISSN] 0360-3016
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
  •  go-up   go-down


52. Corns R, Crocker M, Kumar A, Salisbury J, Tolias C, Sadler G, Hill M: Low grade cerebellar T-cell lymphoma: a novel response to treatment; a case report. Acta Neurochir (Wien); 2010 Jun;152(6):1075-7
Hazardous Substances Data Bank. METHOTREXATE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Low grade cerebellar T-cell lymphoma: a novel response to treatment; a case report.
  • We present a case developing in a previously fit young woman presenting with symptoms of raised intracranial pressure and found on CT to have a cerebellar mass.
  • [MeSH-major] Antimetabolites, Antineoplastic / therapeutic use. Cerebellar Neoplasms / drug therapy. Cerebellar Neoplasms / radiotherapy. Cranial Irradiation. Lymphoma, T-Cell / drug therapy. Lymphoma, T-Cell / radiotherapy. Methotrexate / therapeutic use
  • [MeSH-minor] Adult. Antineoplastic Agents, Hormonal / therapeutic use. Biomarkers, Tumor / analysis. Biopsy. Cerebellum / pathology. Combined Modality Therapy. Dexamethasone / therapeutic use. Dose-Response Relationship, Drug. Female. Humans. Infusions, Intravenous. Ki-67 Antigen / analysis. Magnetic Resonance Imaging. Neurologic Examination. Radiotherapy, Adjuvant. Tomography, X-Ray Computed

  • Hazardous Substances Data Bank. DEXAMETHASONE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19936608.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Austria
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Antineoplastic Agents, Hormonal; 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 7S5I7G3JQL / Dexamethasone; YL5FZ2Y5U1 / Methotrexate
  •  go-up   go-down


53. Carpenter EL, Vance BA, Klein RS, Voloschin A, Dalmau J, Vonderheide RH: Functional analysis of CD8+ T cell responses to the onconeural self protein cdr2 in patients with paraneoplastic cerebellar degeneration. J Neuroimmunol; 2008 Jan;193(1-2):173-82
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Functional analysis of CD8+ T cell responses to the onconeural self protein cdr2 in patients with paraneoplastic cerebellar degeneration.
  • Paraneoplastic cerebellar degeneration (PCD) is linked to an immune response against cerebellar degeneration related antigen 2 (cdr2) co-expressed in tumor and Purkinje neurons.
  • [MeSH-major] CD8-Positive T-Lymphocytes / immunology. Nerve Tissue Proteins / immunology. Paraneoplastic Cerebellar Degeneration / immunology
  • [MeSH-minor] Adult. Aged. Female. HLA-A2 Antigen / metabolism. Humans. Interferon-gamma / biosynthesis. Lymphocyte Activation. Lysosomal-Associated Membrane Protein 1 / analysis. Middle Aged. Tumor Necrosis Factor-alpha / biosynthesis

  • Genetic Alliance. consumer health - Cerebellar Degeneration.
  • Genetic Alliance. consumer health - Paraneoplastic cerebellar degeneration.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18053582.001).
  • [ISSN] 0165-5728
  • [Journal-full-title] Journal of neuroimmunology
  • [ISO-abbreviation] J. Neuroimmunol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / CDR2 protein, human; 0 / HLA-A2 Antigen; 0 / Lysosomal-Associated Membrane Protein 1; 0 / Nerve Tissue Proteins; 0 / Tumor Necrosis Factor-alpha; 82115-62-6 / Interferon-gamma
  •  go-up   go-down


54. Myong NH, Park BJ: Malignant glioma arising at the site of an excised cerebellar hemangioblastoma after irradiation in a von Hippel-Lindau disease patient. Yonsei Med J; 2009 Aug 31;50(4):576-81
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant glioma arising at the site of an excised cerebellar hemangioblastoma after irradiation in a von Hippel-Lindau disease patient.
  • The patient was a 25 year-old male with multiple hemangioblastomas at the cerebellum and spinal cord, multiple pancreatic cysts and a renal cell carcinoma; he was diagnosed as having VHL disease.
  • The largest hemangioblastoma at the right cerebellar hemisphere was completely removed, and he received high-dose irradiation postoperatively.
  • The tumor recurred at the same site 7 years later, which was a malignant glioma with no evidence of hemangioblastoma.
  • The malignant glioma showed molecular genetic profiles of radiation-induced tumors because of its diffuse p53 immunostaining and the loss of p16 immunoreactivity.
  • The genetic study to find the loss of heterozygosity (LOH) of VHL gene revealed that only the cerebellar hemangioblastoma showed allelic losses for the gene.
  • [MeSH-major] Cerebellar Neoplasms / surgery. Glioma / diagnosis. Glioma / etiology. Hemangioblastoma / surgery. Radiotherapy / adverse effects. von Hippel-Lindau Disease / radiotherapy
  • [MeSH-minor] Adult. Humans. Male

  • Genetic Alliance. consumer health - Glioma.
  • Genetic Alliance. consumer health - Hemangioblastoma.
  • MedlinePlus Health Information. consumer health - Radiation Therapy.
  • MedlinePlus Health Information. consumer health - Von Hippel-Lindau Disease.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Br J Neurosurg. 1999 Oct;13(5):504-7 [10627785.001]
  • [Cites] J Med Genet. 2006 Apr;43(4):289-94 [16155191.001]
  • [Cites] Oncogene. 2003 Oct 13;22(45):6988-93 [14557802.001]
  • [Cites] Am J Med. 1984 Jul;77(1):147-50 [6331159.001]
  • [Cites] Cancer. 1986 Aug 15;58(4):886-94 [2424587.001]
  • [Cites] J Natl Cancer Inst. 1994 Jan 19;86(2):142-3 [8271299.001]
  • [Cites] J Neurosurg. 1995 Jul;83(1):154-62 [7782835.001]
  • [Cites] Radiat Res. 1996 Sep;146(3):247-58 [8752302.001]
  • [Cites] Cancer Res. 1997 Mar 15;57(6):1035-8 [9067265.001]
  • [Cites] Cancer. 1998 Jan 1;82(1):8-34 [9428476.001]
  • [Cites] Neurosurgery. 1998 Jan;42(1):172-8 [9442520.001]
  • [Cites] Am J Pathol. 1999 May;154(5):1431-8 [10329596.001]
  • [Cites] J Neurosurg. 2005 May;102(4 Suppl):417-22 [15926395.001]
  • [Cites] J Neurooncol. 2005 Jul;73(3):273-5 [15980980.001]
  • [Cites] Acta Neurochir (Wien). 2001;143(7):697-700 [11534690.001]
  • (PMID = 19718409.001).
  • [ISSN] 1976-2437
  • [Journal-full-title] Yonsei medical journal
  • [ISO-abbreviation] Yonsei Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2730623
  • [Keywords] NOTNLM ; Cerebellar neoplasms / hemangioblastoma / malignant glioma / radiation / von Hippel-Lindau disease
  •  go-up   go-down


55. Ongürü O, Karslioglu Y, Ozcan A, Celik E: Anti-apoptotic and growth-promoting markers in adult medulloblastomas. Clin Neuropathol; 2010 Nov-Dec;29(6):384-9
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anti-apoptotic and growth-promoting markers in adult medulloblastomas.
  • AIM: the aim of this study was to investigate the pathologic features, proliferation potential and expression of some anti-apoptotic and growth-promoting markers in adult medulloblastomas.
  • METHOD: we analyzed the immunohistochemical expression of survivin, c-KIT, Bcl-2, fascin, p-53 and Ki-67 in 18 adult medulloblastomas (> 16 years of age).
  • CONCLUSION: frequent nuclear survivin expression implies the predominance of anti-apoptotic factors in pathogenesis of adult medulloblastomas.
  • It may also be a potential therapeutic target for adult medulloblastomas.
  • Although Blc-2 immunoreactivity was previously reported in approximately 30% in medulloblastomas, we have observed that it is rarely expressed in the present series of adult medulloblastomas.
  • Mild-to-moderate cytoplasmic c-KIT immunoreactivity without membranous staining in adult medulloblastomas may support the previous studies reporting low level of c-KIT protein expression with lack of activating mutations in medulloblastomas.
  • It seems p53 is rarely involved in the course of develepment of adult medulloblastomas.
  • [MeSH-major] Apoptosis Regulatory Proteins / metabolism. Cerebellar Neoplasms / metabolism. Growth Substances / metabolism. Medulloblastoma / metabolism
  • [MeSH-minor] Adolescent. Adult. Biomarkers, Tumor / metabolism. Carrier Proteins / metabolism. Female. Humans. Inhibitor of Apoptosis Proteins. Male. Microfilament Proteins / metabolism. Microtubule-Associated Proteins / metabolism. Middle Aged. Proto-Oncogene Proteins c-bcl-2 / metabolism. Proto-Oncogene Proteins c-kit / metabolism. Retrospective Studies. Tumor Suppressor Protein p53 / metabolism. Young Adult

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21073843.001).
  • [ISSN] 0722-5091
  • [Journal-full-title] Clinical neuropathology
  • [ISO-abbreviation] Clin. Neuropathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Apoptosis Regulatory Proteins; 0 / BIRC5 protein, human; 0 / Biomarkers, Tumor; 0 / Carrier Proteins; 0 / Growth Substances; 0 / Inhibitor of Apoptosis Proteins; 0 / Microfilament Proteins; 0 / Microtubule-Associated Proteins; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / Tumor Suppressor Protein p53; 146808-54-0 / fascin; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
  •  go-up   go-down


56. Capovilla M, Kambouchner M, Bernier M, Soulier A, Tissier F, Saintigny P: Late cerebellar relapse of a juvenile bronchial carcinoid. Clin Lung Cancer; 2007 Mar;8(5):339-41
MedlinePlus Health Information. consumer health - Carcinoid Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Late cerebellar relapse of a juvenile bronchial carcinoid.
  • Although epithelial bronchial neoplasm is a cancer frequently observed in adult patients, it is rarely observed in patients who are children.
  • The most frequent histologic subtype is well differentiated neuroendocrine tumor, or carcinoid.
  • They have a variable biologic behavior, ranging from benign to malignant tumors capable of very late recurrence or metastasis.
  • We report the case of a child with a pulmonary carcinoid initially considered typical, who presented with relapse in the cerebellum and mediastinum 16 years later.
  • After review of the pathology slides, primary and metastatic tumors were reclassified as atypical carcinoid according to the criteria of the 2004 World Health Organization classification of lung tumors.
  • [MeSH-major] Bronchial Neoplasms / pathology. Carcinoid Tumor / pathology. Cerebellar Neoplasms / diagnosis. Cerebellar Neoplasms / secondary. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / secondary
  • [MeSH-minor] Adolescent. Adult. Humans. Male

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17562235.001).
  • [ISSN] 1525-7304
  • [Journal-full-title] Clinical lung cancer
  • [ISO-abbreviation] Clin Lung Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


57. Jarius S, Wandinger KP, Horn S, Heuer H, Wildemann B: A new Purkinje cell antibody (anti-Ca) associated with subacute cerebellar ataxia: immunological characterization. J Neuroinflammation; 2010;7:21
antibodies-online. View related products from antibodies-online.com (subscription/membership/fee required).

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A new Purkinje cell antibody (anti-Ca) associated with subacute cerebellar ataxia: immunological characterization.
  • We report on a newly discovered serum and cerebrospinal fluid (CSF) reactivity to Purkinje cells (PCs) associated with subacute inflammatory cerebellar ataxia.
  • Immunohistochemical studies on mouse, rat, and monkey brain sections revealed binding of a high-titer (up to 1:10,000) IgG antibody to the cerebellar molecular layer, Purkinje cell (PC) layer, and white matter.
  • Western blotting of primate cerebellum extract revealed binding of CSF and serum IgG to an 80-97 kDa protein.
  • Extensive control studies were performed to rule out a broad panel of previously described paraneoplastic and non-paraneoplastic antibodies known to be associated with cerebellar ataxia.
  • Our findings suggest a role of autoimmunity against ARHGAP26 in the pathogenesis of subacute inflammatory cerebellar ataxia, and extend the panel of diagnostic markers for this devastating disease.
  • [MeSH-major] Antigens, Tumor-Associated, Carbohydrate / immunology. Cerebellar Ataxia / immunology. Cerebellar Ataxia / pathology. Immunoglobulin G / metabolism. Purkinje Cells / immunology
  • [MeSH-minor] Adult. Animals. Animals, Newborn. Calbindins. Cells, Cultured. Cerebellum / cytology. Female. GTPase-Activating Proteins / metabolism. Glial Fibrillary Acidic Protein / metabolism. Humans. Inositol 1,4,5-Trisphosphate Receptors / metabolism. Magnetic Resonance Imaging / methods. Mice. Molecular Weight. Parvalbumins / metabolism. Protein Array Analysis / methods. S100 Calcium Binding Protein G / metabolism

  • Genetic Alliance. consumer health - Cerebellar Ataxia.
  • Genetic Alliance. consumer health - Ataxia.
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):9168-73 [10908648.001]
  • [Cites] J Neuroinflammation. 2009;6:31 [19874605.001]
  • [Cites] Ann Neurol. 2001 Feb;49(2):146-54 [11220734.001]
  • [Cites] Brain. 2001 Jun;124(Pt 6):1138-48 [11353730.001]
  • [Cites] Ann Neurol. 2001 Sep;50(3):301-11 [11558786.001]
  • [Cites] Ann Neurol. 2001 Nov;50(5):688-91 [11706981.001]
  • [Cites] J Child Neurol. 2002 Feb;17(2):147-9 [11952078.001]
  • [Cites] J Neurol Sci. 2002 Sep 15;201(1-2):9-12 [12163187.001]
  • [Cites] Neurology. 2002 Sep 10;59(5):764-6 [12221175.001]
  • [Cites] J Neuroimmunol. 2002 Nov;132(1-2):72-82 [12417436.001]
  • [Cites] Ann Neurol. 2003 Mar;53(3):325-36 [12601700.001]
  • [Cites] Lancet Neurol. 2002 Sep;1(5):294-305 [12849427.001]
  • [Cites] Lancet Neurol. 2002 Nov;1(7):408; discussion 408 [12849362.001]
  • [Cites] J Neurol. 2004 Jan;251(1):47-52 [14999489.001]
  • [Cites] Neurology. 2004 Mar 9;62(5):778-82 [15007130.001]
  • [Cites] J Neurol Neurosurg Psychiatry. 2004 Aug;75(8):1135-40 [15258215.001]
  • [Cites] Arch Neurol. 1976 Sep;33(9):660-1 [962649.001]
  • [Cites] Lancet. 1985 Jun 8;1(8441):1313-5 [2860501.001]
  • [Cites] Trends Neurosci. 1989 Dec;12(12):496-502 [2480664.001]
  • [Cites] Clin Chem. 1991 Jul;37(7):1153-60 [1855284.001]
  • [Cites] J Neurol Sci. 1991 Nov;106(1):82-7 [1779243.001]
  • [Cites] Neurology. 1992 Oct;42(10):1931-7 [1407575.001]
  • [Cites] J Invest Dermatol. 1993 Mar;100(3):316-22 [8440912.001]
  • [Cites] N Engl J Med. 2000 Jan 6;342(1):21-7 [10620645.001]
  • [Cites] Ann Neurol. 2000 Mar;47(3):297-305 [10716248.001]
  • [Cites] Neuron. 1994 Feb;12(2):243-60 [8110456.001]
  • [Cites] J Neurol Sci. 1994 Dec 20;127(2):153-8 [7707074.001]
  • [Cites] Clin Neurol Neurosurg. 1995 Feb;97(1):101-5 [7788964.001]
  • [Cites] J Immunol. 1996 Sep 1;157(5):2082-8 [8757330.001]
  • [Cites] J Neuroimmunol. 1997 Apr;74(1-2):55-61 [9119979.001]
  • [Cites] J Biol Chem. 1997 May 16;272(20):13419-25 [9148966.001]
  • [Cites] J Clin Invest. 1997 Jul 1;100(1):25-31 [9202053.001]
  • [Cites] Mult Scler. 1998 Jun;4(3):99-107 [9762655.001]
  • [Cites] Neurology. 1998 Oct;51(4):1146-50 [9781545.001]
  • [Cites] Ann Neurol. 1999 Feb;45(2):162-7 [9989617.001]
  • [Cites] Neurology. 1999 Sep 22;53(5):1107-14 [10496275.001]
  • [Cites] J Neurooncol. 2005 Feb;71(3):231-6 [15735910.001]
  • [Cites] Lancet. 2005 Apr 16-22;365(9468):1406-11 [15836889.001]
  • [Cites] Lancet Neurol. 2006 Jun;5(6):513-24 [16713923.001]
  • [Cites] Neurology. 2006 Sep 26;67(6):1068-70 [17000981.001]
  • [Cites] J Neurol Neurosurg Psychiatry. 2006 Dec;77(12):1359-62 [16801349.001]
  • [Cites] Neurology. 2007 Jan 16;68(3):239-40 [17224583.001]
  • [Cites] Brain Dev. 2007 May;29(4):224-6 [17008044.001]
  • [Cites] Brain Dev. 2007 May;29(4):254-6 [17049194.001]
  • [Cites] Neurology. 2007 Mar 27;68(13):1076-7 [17287449.001]
  • [Cites] Neurology. 2007 Dec 11;69(24):2221-31 [17928579.001]
  • [Cites] Nat Clin Pract Neurol. 2008 Apr;4(4):202-14 [18334978.001]
  • [Cites] Arch Neurol. 2008 Jul;65(7):913-9 [18625857.001]
  • [Cites] Ann Neurol. 2008 Sep;64(3):332-43 [18825674.001]
  • [Cites] Lancet Neurol. 2008 Oct;7(10):939-50 [18848313.001]
  • [Cites] Curr Biol. 2008 Nov 25;18(22):1802-8 [19036340.001]
  • [Cites] Arch Neurol. 2001 Feb;58(2):225-30 [11176960.001]
  • (PMID = 20226058.001).
  • [ISSN] 1742-2094
  • [Journal-full-title] Journal of neuroinflammation
  • [ISO-abbreviation] J Neuroinflammation
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / ARHGAP26 protein, human; 0 / Antigens, Tumor-Associated, Carbohydrate; 0 / Calbindins; 0 / GTPase-Activating Proteins; 0 / Glial Fibrillary Acidic Protein; 0 / Immunoglobulin G; 0 / Inositol 1,4,5-Trisphosphate Receptors; 0 / Parvalbumins; 0 / S100 Calcium Binding Protein G
  • [Other-IDs] NLM/ PMC2848133
  •  go-up   go-down


58. Glassmann A, Molly S, Surchev L, Nazwar TA, Holst M, Hartmann W, Baader SL, Oberdick J, Pietsch T, Schilling K: Developmental expression and differentiation-related neuron-specific splicing of metastasis suppressor 1 (Mtss1) in normal and transformed cerebellar cells. BMC Dev Biol; 2007;7:111
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Developmental expression and differentiation-related neuron-specific splicing of metastasis suppressor 1 (Mtss1) in normal and transformed cerebellar cells.
  • BACKGROUND: Mtss1 encodes an actin-binding protein, dysregulated in a variety of tumors, that interacts with sonic hedgehog/Gli signaling in epidermal cells.
  • Given the prime importance of this pathway for cerebellar development and tumorigenesis, we assessed expression of Mtss1 in the developing murine cerebellum and human medulloblastoma specimens.
  • In the adult CNS, Mtss1 is found exclusively in cerebellar Purkinje cells.
  • Whereas immature granule cells express a Mtss1 variant observed also in peripheral tissues and comprising exon 12, this exon is replaced by a CNS-specific exon, 12a, in more mature granule cells and in adult Purkinje cells.
  • Bioinformatic analysis of Mtss1 suggests that differential exon usage may affect interaction with Fyn and Src, two tyrosine kinases previously recognized as critical for cerebellar cell migration and histogenesis.
  • CONCLUSION: Both the pattern of expression and splicing of Mtss1 is developmentally regulated in the murine cerebellum.
  • These findings are discussed with a view on the potential role of Mtss1 for cytoskeletal dynamics in developing and mature cerebellar neurons.
  • [MeSH-major] Cell Transformation, Neoplastic / pathology. Cerebellum / growth & development. Gene Expression Regulation, Developmental. Microfilament Proteins / genetics. Neoplasm Proteins / genetics
  • [MeSH-minor] Animals. Cerebellar Neoplasms / pathology. Exons. Humans. Mice. Mice, Inbred C57BL. Mice, Transgenic. Polymerase Chain Reaction. Protein Splicing / genetics. Purkinje Cells / pathology. Tumor Cells, Cultured

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Nature. 1996 Feb 29;379(6568):837-40 [8587609.001]
  • [Cites] Neuron. 1996 Mar;16(3):587-99 [8785056.001]
  • [Cites] Biotechniques. 1997 May;22(5):812-4 [9149852.001]
  • [Cites] Cancer Res. 1997 Jun 1;57(11):2085-8 [9187099.001]
  • [Cites] Int J Dev Neurosci. 1997 Oct;15(6):749-54 [9402225.001]
  • [Cites] DNA Res. 1997 Oct 31;4(5):307-13 [9455477.001]
  • [Cites] Brain Pathol. 1998 Jan;8(1):13-8 [9458162.001]
  • [Cites] Trends Neurosci. 1998 Sep;21(9):383-90 [9735946.001]
  • [Cites] J Immunol Methods. 1998 Jun 1;215(1-2):45-58 [9744747.001]
  • [Cites] Neuron. 1999 Jan;22(1):103-14 [10027293.001]
  • [Cites] Trends Biochem Sci. 1999 Jan;24(1):34-6 [10087920.001]
  • [Cites] Eur J Neurosci. 1999 Sep;11(9):3199-214 [10510184.001]
  • [Cites] Genes Dev. 2004 Nov 15;18(22):2724-9 [15545630.001]
  • [Cites] Dev Biol. 2005 Jan 15;277(2):366-77 [15617680.001]
  • [Cites] Nat Biotechnol. 2005 Jan;23(1):94-101 [15592455.001]
  • [Cites] EMBO J. 2005 Jan 26;24(2):240-50 [15635447.001]
  • [Cites] J Neurosci. 2005 Jan 26;25(4):869-79 [15673667.001]
  • [Cites] Brain Res Mol Brain Res. 2002 Sep 30;105(1-2):1-10 [12399102.001]
  • [Cites] Curr Opin Cell Biol. 2003 Feb;15(1):73-81 [12517707.001]
  • [Cites] J Biol Chem. 2003 Mar 7;278(10):8452-9 [12482861.001]
  • [Cites] Am J Hum Genet. 2003 Apr;72(4):918-30 [12621583.001]
  • [Cites] Cerebellum. 2006;5(2):77-88 [16818382.001]
  • [Cites] Eur J Neurosci. 2006 Jul;24(2):466-78 [16903854.001]
  • [Cites] Cell. 2006 Oct 6;127(1):213-26 [17018287.001]
  • [Cites] J Biol Chem. 2006 Nov 17;281(46):35347-58 [17003044.001]
  • [Cites] Eur J Neurosci. 2006 Nov;24(9):2491-503 [17100838.001]
  • [Cites] Nat Cell Biol. 2006 Dec;8(12):1337-47 [17115031.001]
  • [Cites] Mol Cell Neurosci. 2006 Dec;33(4):447-58 [17049261.001]
  • [Cites] Nature. 2007 Jan 11;445(7124):168-76 [17151600.001]
  • [Cites] Structure. 2007 Feb;15(2):145-55 [17292833.001]
  • [Cites] J Biol Chem. 2007 Mar 9;282(10):7624-31 [17224454.001]
  • [Cites] J Cell Biol. 2007 Mar 26;176(7):953-64 [17371834.001]
  • [Cites] Oncogene. 2007 Apr 5;26(16):2308-17 [17016438.001]
  • [Cites] Curr Biol. 2007 Jun 19;17(12):R455-7 [17580073.001]
  • [Cites] Proc Natl Acad Sci U S A. 1999 Nov 9;96(23):13438-43 [10557339.001]
  • [Cites] J Mol Biol. 1999 Dec 17;294(5):1351-62 [10600390.001]
  • [Cites] J Mol Biol. 2000 Apr 14;297(5):1183-94 [10764582.001]
  • [Cites] Trends Neurosci. 2000 Aug;23(8):372-6 [10906801.001]
  • [Cites] Physiol Rev. 2003 Apr;83(2):433-73 [12663865.001]
  • [Cites] Biochem J. 2003 Apr 15;371(Pt 2):463-71 [12570871.001]
  • [Cites] Nucleic Acids Res. 2003 Jul 1;31(13):3625-30 [12824381.001]
  • [Cites] J Cell Biol. 2005 Jan 31;168(3):453-63 [15684034.001]
  • [Cites] J Comp Neurol. 2005 Mar 14;483(3):318-28 [15682397.001]
  • [Cites] Nat Rev Neurosci. 2005 Mar;6(3):201-14 [15711600.001]
  • [Cites] Oncogene. 2005 Mar 17;24(12):2059-66 [15688017.001]
  • [Cites] Am J Pathol. 2005 Apr;166(4):1153-62 [15793295.001]
  • [Cites] Cell Mol Life Sci. 2005 May;62(9):955-70 [15868099.001]
  • [Cites] Int J Oncol. 2005 Jun;26(6):1699-705 [15870888.001]
  • [Cites] Biochem J. 2005 Sep 15;390(Pt 3):641-53 [16134966.001]
  • [Cites] J Neurosci. 2005 Sep 14;25(37):8578-86 [16162939.001]
  • [Cites] J Cell Sci. 2005 Nov 15;118(Pt 22):5393-403 [16280553.001]
  • [Cites] Physiology (Bethesda). 2006 Feb;21:38-47 [16443821.001]
  • [Cites] Nat Methods. 2006 Mar;3(3):175-7 [16489333.001]
  • [Cites] PLoS Biol. 2006 Apr;4(4):e86 [16602821.001]
  • [Cites] Mol Cell. 2006 Jun 23;22(6):851-68 [16793553.001]
  • [Cites] Mol Biol Cell. 2006 Jul;17(7):3187-96 [16687575.001]
  • [Cites] J Neurosci. 2000 Aug 15;20(16):5899-905 [10934236.001]
  • [Cites] Nature. 2000 Dec 7;408(6813):732-5 [11130076.001]
  • [Cites] Cell. 2000 Dec 22;103(7):1001-4 [11163176.001]
  • [Cites] Nature. 2002 Jan 24;415(6870):436-42 [11807556.001]
  • [Cites] Nat Neurosci. 2002 Mar;5(3):239-46 [11850630.001]
  • [Cites] FEBS Lett. 2002 Feb 20;513(1):58-66 [11911881.001]
  • [Cites] Neoplasia. 2002 Jul-Aug;4(4):291-4 [12082544.001]
  • [Cites] Dev Genes Evol. 2002 Sep;212(8):403-6 [12203097.001]
  • [Cites] Annu Rev Cell Dev Biol. 2002;18:601-35 [12142283.001]
  • [Cites] Nucleic Acids Res. 2003 Jul 1;31(13):3635-41 [12824383.001]
  • [Cites] Nucleic Acids Res. 2003 Jul 1;31(13):3709-11 [12824399.001]
  • [Cites] J Neurosci Res. 2003 Aug 1;73(3):400-9 [12868073.001]
  • [Cites] J Biol Chem. 2003 Jul 25;278(30):27981-7 [12695505.001]
  • [Cites] Cell. 2004 Jan 23;116(2):191-203 [14744431.001]
  • [Cites] J Biol Chem. 2004 Apr 9;279(15):14929-36 [14752106.001]
  • [Cites] Brain Res Dev Brain Res. 2004 Jun 21;150(2):177-90 [15158081.001]
  • [Cites] Nat Neurosci. 2004 Sep;7(9):923-9 [15286792.001]
  • [Cites] Neuron. 2004 Oct 14;44(2):321-34 [15473970.001]
  • [Cites] Cancer Lett. 2004 Nov 25;215(2):209-20 [15488640.001]
  • [Cites] Protein Eng Des Sel. 2004 Jun;17(6):527-36 [15314210.001]
  • [Cites] Development. 2004 Nov;131(22):5581-90 [15496441.001]
  • [Cites] J Neuropathol Exp Neurol. 1985 Nov;44(6):592-605 [4056828.001]
  • [Cites] Science. 1990 Apr 13;248(4952):223-6 [2109351.001]
  • [Cites] Neuroscience. 1993 Mar;53(1):121-30 [8097019.001]
  • [Cites] J Biol Chem. 1995 Apr 14;270(15):8730-8 [7721778.001]
  • (PMID = 17925019.001).
  • [ISSN] 1471-213X
  • [Journal-full-title] BMC developmental biology
  • [ISO-abbreviation] BMC Dev. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Microfilament Proteins; 0 / Mtss1 protein, mouse; 0 / Neoplasm Proteins
  • [Other-IDs] NLM/ PMC2194783
  •  go-up   go-down


59. Francesco F, Maurizio I, Stefano C, Marina S, Ugo S, Massimo S: Trigeminal nerve root entry zone pilocytic astrocytoma in an adult: a rare case of an extraparenchymal tumor. J Neurooncol; 2010 Apr;97(2):285-90
Genetic Alliance. consumer health - Pilocytic astrocytoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Trigeminal nerve root entry zone pilocytic astrocytoma in an adult: a rare case of an extraparenchymal tumor.
  • Extra-axial cerebellopontine angle (CPA) tumors account for approximately 10% of all brain neoplasms in adults.
  • Gliomas in the CPA are rare and quite often are the exophytic extension of primary brain stem or cerebellar tumors.
  • We describe a pilocytic astrocytoma of the CPA that was found to arise from the proximal portion of trigeminal nerve without any anatomic continuity with the brain stem and the cerebellum.
  • The proposed origin of this extremely rare tumor is the root entry zone of the involved nerve.
  • The tumor was completely resected via a suboccipital retrosigmoid approach.
  • [MeSH-major] Astrocytoma / pathology. Cerebellar Neoplasms / pathology. Cerebellopontine Angle / pathology. Cranial Nerve Neoplasms / pathology. Trigeminal Nerve Diseases / pathology
  • [MeSH-minor] Adult. Female. Humans. Magnetic Resonance Imaging

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Arch Otolaryngol. 1980 Aug;106(8):456-9 [7396789.001]
  • [Cites] J Laryngol Otol. 1980 Dec;94(12):1353-62 [7441048.001]
  • [Cites] Surg Neurol. 2008 Jul;70(1):87-91 [18313733.001]
  • [Cites] J Neuropathol Exp Neurol. 1948 Oct;7(4):349-67 [18889208.001]
  • [Cites] J Neurosurg. 1993 Jun;78(6):859-63 [8487066.001]
  • [Cites] J Neurooncol. 2000 Sep;49(3):205-12 [11212899.001]
  • [Cites] Eur Radiol. 2004 Jul;14(7):1169-73 [14740164.001]
  • [Cites] Neuroradiology. 1993;35(4):274-8 [8492893.001]
  • [Cites] Bull Johns Hopkins Hosp. 1948 Sep;83(3):187-212 [18877371.001]
  • [Cites] Neurosurgery. 2006 Oct;59(4):E939-40; discussion E940 [17038929.001]
  • [Cites] Neurosurgery. 1995 Jul;37(1):125-8 [8587672.001]
  • [Cites] Childs Nerv Syst. 2009 Feb;25(2):247-51 [18690462.001]
  • [Cites] Am J Otolaryngol. 1980 Feb;1(2):141-6 [7446836.001]
  • (PMID = 19820900.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


60. Tan CC, Gonzales M, Veitch A: Clinical implications of the infratentorial rosette-forming glioneuronal tumor: case report. Neurosurgery; 2008 Jul;63(1):E175-6; discussion E176

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical implications of the infratentorial rosette-forming glioneuronal tumor: case report.
  • OBJECTIVE: This article describes our experience with two patients who presented with unusual tumors in the cerebellar vermis and cerebral aqueduct.
  • Although sparing the fourth ventricle proper, both tumors had histological features consistent with the rare diagnosis of a rosette-forming glioneuronal tumor of the fourth ventricle, of which only 19 cases have been reported previously.
  • Patient 2 was a 38-year-old woman with a long history of intermittent giddiness, no neurological signs, and a magnetic resonance imaging scan that demonstrated a nonenhancing and subtle abnormality in the cerebellar vermis.
  • CONCLUSION: These cases demonstrate that the rosette-forming glioneuronal tumor may be more accurately categorized as an infratentorial tumor rather than a tumor of the fourth ventricle.
  • Because the literature indicates that this is a tumor with little potential for malignant behavior and considerable morbidity can accompany attempts at resection, a conservative management approach would seem well advised.
  • If this tumor is to be managed conservatively, because of the paucity of extended follow-up data, long-term radiological and clinical surveillance is strongly recommended.
  • [MeSH-major] Cerebellar Neoplasms / diagnosis. Cerebral Ventricle Neoplasms / diagnosis. Infratentorial Neoplasms / diagnosis. Rosette Formation
  • [MeSH-minor] Adult. Female. Humans. Male

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18728557.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 14
  •  go-up   go-down


61. Menon G, Krishnakumar K, Nair S: Adult medulloblastoma: clinical profile and treatment results of 18 patients. J Clin Neurosci; 2008 Feb;15(2):122-6
MedlinePlus Health Information. consumer health - Clinical Trials.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adult medulloblastoma: clinical profile and treatment results of 18 patients.
  • The objective of this article is to examine the clinicoradiological features and surgical outcomes of adult patients (>16 years) with medulloblastoma.
  • The tumor was located in the vermis in 12 patients (66.6%) and in the cerebellar hemisphere in six (16.6%).
  • Desmoplastic variant histology was not observed to be a significant prognostic factor in the adult group while brain stem invasion carried a poor prognosis.
  • [MeSH-major] Cerebellar Neoplasms / therapy. Clinical Trials as Topic. Medulloblastoma / therapy
  • [MeSH-minor] Adolescent. Adult. Age Factors. Female. Humans. Male. Middle Aged. Prognosis. Retrospective Studies. Statistics, Nonparametric. Treatment Outcome

  • Genetic Alliance. consumer health - Medulloblastoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18078755.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
  •  go-up   go-down


62. Chang Q, Ng HK: [Different hypermethylation status of RASSF1A in medulloblastoma and supratentorial primitive neuroectodermal tumor]. Zhonghua Bing Li Xue Za Zhi; 2007 Jan;36(1):24-8
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Different hypermethylation status of RASSF1A in medulloblastoma and supratentorial primitive neuroectodermal tumor].
  • OBJECTIVE: To investigate the epigenetic involvement of RASSF1A in intracranial primitive neuroectodermal tumors (PNETs) and compare the methylation patterns between medulloblastoma (MBs) and supratentorial PNETs (SPNETs).
  • RESULTS: The results revealed no promoter hypermethylation of RASSF1A in 2 normal cerebellar and 5 normal cerebral tissue specimens examined.
  • These results demonstrated that such epigenetic alteration was tumor-specific.
  • Different hypermethylation status of RASSF1A are found in PNET subtypes suggesting that MBs and SPNETs are epigenetical distinct tumors.
  • [MeSH-major] Brain Neoplasms / genetics. Cerebellar Neoplasms / genetics. Medulloblastoma / genetics. Neuroectodermal Tumors, Primitive / genetics. Tumor Suppressor Proteins / genetics
  • [MeSH-minor] Adolescent. Adult. Aged. Cell Line, Tumor. Child. Child, Preschool. DNA Methylation. Female. Gene Expression Regulation, Neoplastic. Gene Silencing. HeLa Cells. Humans. Infant. Male. Promoter Regions, Genetic / genetics. Reverse Transcriptase Polymerase Chain Reaction. Young Adult


63. Karasaki H, Ishizaki A, Yanagawa N, Nakano Y, Sasajima J, Mizukami Y, Tanno S, Tokusashi Y, Miyokawa N, Obara M, Goto J, Kino S, Kono T, Kasai S: [Two cases of pancreatic tumor with von Hippel-Lindau disease]. Nihon Shokakibyo Gakkai Zasshi; 2008 May;105(5):725-31
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Two cases of pancreatic tumor with von Hippel-Lindau disease].
  • Adrenal pheochromocytoma, spinal hemangioblastoma and pancreatic endocrine tumor were resected.
  • The second case was a 68-year-old woman with past surgical histories included cerebellar and spinal hemangioblastoma.
  • We considered VHL disease from coexistent multiple tumors include pancreatic involvements and finally diagnosed by genetic examination in both cases.
  • [MeSH-major] Cystadenoma, Serous / complications. Cystadenoma, Serous / surgery. Neoplasms, Multiple Primary. Pancreatic Neoplasms / complications. Pancreatic Neoplasms / surgery. von Hippel-Lindau Disease / complications. von Hippel-Lindau Disease / diagnosis
  • [MeSH-minor] Adult. Aged. Female. Humans. Molecular Diagnostic Techniques. Pancreatectomy

  • MedlinePlus Health Information. consumer health - Pancreatic Cancer.
  • MedlinePlus Health Information. consumer health - Von Hippel-Lindau Disease.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18460863.001).
  • [ISSN] 0446-6586
  • [Journal-full-title] Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
  • [ISO-abbreviation] Nihon Shokakibyo Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


64. Rasmussen A, Nava-Salazar S, Yescas P, Alonso E, Revuelta R, Ortiz I, Canizales-Quinteros S, Tusié-Luna MT, López-López M: Von Hippel-Lindau disease germline mutations in Mexican patients with cerebellar hemangioblastoma. J Neurosurg; 2006 Mar;104(3):389-94
MedlinePlus Health Information. consumer health - Von Hippel-Lindau Disease.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Von Hippel-Lindau disease germline mutations in Mexican patients with cerebellar hemangioblastoma.
  • OBJECT: Central nervous system (CNS) hemangioblastomas are benign vascular tumors arising either sporadically or as a manifestation of von Hippel-Lindau (VHL) disease, a hereditary cancer syndrome.
  • The authors studied a series of patients with CNS hemangioblastomas and their families to identify germline mutations in the VHL tumor suppressor gene and to establish a predictive testing and screening protocol.
  • All asymptomatic mutation carriers underwent genetic counseling and tumor surveillance.
  • [MeSH-minor] Adolescent. Adult. Cerebellar Neoplasms. Child. Child, Preschool. DNA Mutational Analysis. Female. Genetic Testing. Humans. Male. Mexico. Middle Aged. Pedigree. Prognosis

  • Genetic Alliance. consumer health - Hemangioblastoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16572651.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


65. Donovan DJ, Iskandar JI, Citrone MJ, Royer MC: Successful removal of a cerebellar hemangioblastoma in a combat support hospital. Mil Med; 2006 Mar;171(3):211-5
MedlinePlus Health Information. consumer health - Veterans and Military Health.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Successful removal of a cerebellar hemangioblastoma in a combat support hospital.
  • Imaging studies revealed a cystic brain neoplasm causing hydrocephalus and increased intracranial pressure.
  • The tumor was completely removed and the patient's symptoms resolved, allowing safe evacuation.
  • This is the first reported case of a brain tumor successfully removed in a CSH.
  • [MeSH-major] Cerebellar Neoplasms / surgery. Hemangioblastoma / surgery. Hospitals, Military. Hospitals, Packaged. Military Medicine. Military Personnel. Warfare
  • [MeSH-minor] Adult. Humans. Kuwait. Male. Tomography, X-Ray Computed. Treatment Outcome. United States

  • Genetic Alliance. consumer health - Hemangioblastoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16602518.001).
  • [ISSN] 0026-4075
  • [Journal-full-title] Military medicine
  • [ISO-abbreviation] Mil Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


66. Rushing EJ, Smith AB, Smirniotopoulos JG, Douglas AF, Zeng W, Azumi N: Occult leptomeningeal large cell medulloblastoma in an adult. Clin Neuropathol; 2009 May-Jun;28(3):188-92
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Occult leptomeningeal large cell medulloblastoma in an adult.
  • We report the first case of this entity in an adult that proved to be an unsuspected primary leptomeningeal tumor.
  • Postmortem examination of the brain was notable for necrotic cerebellar tonsils, but demonstrated no evidence of an intraparenchymal mass lesion.
  • Microscopic examination of the cerebellum revealed discohesive neoplastic cells, which showed characteristic dot-like immunoreactivity for synaptophysin, diagnostic of large cell medulloblastoma within the subarachnoid space.
  • CONCLUSIONS: Our experience with this unique case illustrates the challenges of diagnosing a primary leptomeningeal neoplasm.
  • This case also underscores the importance of maintaining a high degree of suspicion for leptomeningeal neoplasms in patients who present with imaging studies suspicious for Chiari I malformation.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Medulloblastoma / pathology. Meningeal Neoplasms / pathology
  • [MeSH-minor] Adult. Arnold-Chiari Malformation / complications. Fatal Outcome. Humans. Intervertebral Disc Displacement / complications. Magnetic Resonance Imaging. Male

  • Genetic Alliance. consumer health - Medulloblastoma.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19537136.001).
  • [ISSN] 0722-5091
  • [Journal-full-title] Clinical neuropathology
  • [ISO-abbreviation] Clin. Neuropathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


67. Korshunov A, Remke M, Werft W, Benner A, Ryzhova M, Witt H, Sturm D, Wittmann A, Schöttler A, Felsberg J, Reifenberger G, Rutkowski S, Scheurlen W, Kulozik AE, von Deimling A, Lichter P, Pfister SM: Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification. J Clin Oncol; 2010 Jun 20;28(18):3054-60
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification.
  • PURPOSE: Medulloblastoma (MB) is the most common malignant brain tumor in children, whereas it rarely presents in adults.
  • We aimed to identify genetic aberrations in 146 adult MBs to evaluate age-dependent differences in tumor biology and adapt age-specific risk stratification models.
  • METHODS: As a screening set, we studied a cohort of 34 adult MBs by using array-based comparative genomic hybridization comparing molecular results with clinical data.
  • DNA copy number aberrations identified as possible prognostic markers were validated in an independent cohort of 112 adult patients with MB by fluorescent in situ hybridization analysis.
  • RESULTS: CDK6 amplification, 10q loss, and 17q gain are the most powerful prognostic markers in adult MB.
  • Whereas MYC/MYCN oncogene amplifications had a high prognostic value in pediatric MB, these aberrations were rarely observed in adult tumors.
  • Surprisingly, adult MBs with 6q deletion and nuclear beta-catenin activation did not share the excellent prognosis with their pediatric counterparts.
  • CONCLUSION: Adult MB is distinct from pediatric MB in terms of genomic aberrations and their impact on clinical outcomes.
  • Therefore, adult MBs require age-specific risk stratification models.
  • [MeSH-major] Cerebellar Neoplasms / genetics. Chromosome Aberrations. Medulloblastoma / genetics. Nuclear Proteins / genetics. Oncogene Proteins / genetics. Proto-Oncogene Proteins c-myc / genetics
  • [MeSH-minor] Adolescent. Adult. Algorithms. Biomarkers, Tumor / genetics. Carcinoma, Large Cell / classification. Carcinoma, Large Cell / genetics. Carcinoma, Large Cell / metabolism. Child. Child, Preschool. Chromosomes, Human, Pair 10 / genetics. Chromosomes, Human, Pair 17 / genetics. Chromosomes, Human, Pair 6 / genetics. Comparative Genomic Hybridization. Female. Humans. Immunoenzyme Techniques. In Situ Hybridization, Fluorescence. Infant. Male. Middle Aged. Oligonucleotide Array Sequence Analysis. Prognosis. Risk Assessment. Tissue Array Analysis. Young Adult. beta Catenin / genetics

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20479417.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / MYC protein, human; 0 / MYCN protein, human; 0 / Nuclear Proteins; 0 / Oncogene Proteins; 0 / Proto-Oncogene Proteins c-myc; 0 / beta Catenin
  •  go-up   go-down


68. Beppu T, Hirooka R, Fujiwara S, Kashimura H, Nishimoto H, Ogasawara K, Ogawa A: Choice of posterior subtemporal transtentorial approach for tumor resection in deep anteromedial superior cerebellum. Neurol Med Chir (Tokyo); 2009 Jan;49(1):42-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Choice of posterior subtemporal transtentorial approach for tumor resection in deep anteromedial superior cerebellum.
  • The anteromedial superior cerebellar tumor can be accessed by various routes.
  • For tumor presenting at the cerebellar surface in this region, the optimal approach remains contentious.
  • Furthermore, which of the various routes offers the optimal approach to a tumor that is not present at the cerebellar surface but lies deep anteromedial superior cerebellum is a matter of debate.
  • We report herein the case of a 44-year-old woman with hemangioblastoma deep within the subcortex of the anteromedial superior cerebellum.
  • Preoperative magnetic resonance (MR) imaging and three-dimensional anisotropy contrast MR axonography using diffusion-weighted MR imaging demonstrated that the posterior subtemporal transtentorial (PSTT) approach would provide a shorter surgical corridor, minimal cerebellar split, and better preservation of nerve fibers, compared to the other approaches.
  • Surgical tumor removal was successfully achieved using the PSTT approach.
  • During surgery, the PSTT approach provided an operative field that enabled visualization of the proximal side of the superior cerebellar artery as the tumor feeding vessel.
  • For patients with tumor located within the subcortex of the anteromedial superior cerebellum, the PSTT approach is recommended as an optimal surgical route.
  • [MeSH-major] Cerebellar Neoplasms / surgery. Craniotomy / methods. Hemangioblastoma / surgery
  • [MeSH-minor] Adult. Cerebral Angiography. Cerebral Veins / pathology. Female. Humans. Imaging, Three-Dimensional. Intraoperative Complications / prevention & control. Magnetic Resonance Imaging / methods. Preoperative Care. Surgery, Computer-Assisted

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19169003.001).
  • [ISSN] 1349-8029
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  •  go-up   go-down


69. Vieira Santos A, Vilela P, Mateus L, Saraiva PF, Goulão A: [Central nervous system abnormalities namely secondary brain tumors]. Acta Med Port; 2006 Nov-Dec;19(6):451-4
MedlinePlus Health Information. consumer health - Brain Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Central nervous system abnormalities namely secondary brain tumors].
  • [Transliterated title] Tumor do sistema nervoso central secundário a radioterapia e quimioterapia.
  • Eighteen years later a cerebellar glioblastoma multiforme was diagnosed.
  • The authors speculate about the possibility that this tumor may have been radiation and/or chemotherapy induced.
  • [MeSH-major] Brain Neoplasms / diagnosis. Glioblastoma / diagnosis. Neoplasms, Second Primary / diagnosis. Precursor Cell Lymphoblastic Leukemia-Lymphoma / radiotherapy
  • [MeSH-minor] Adult. Fatal Outcome. Humans. Magnetic Resonance Imaging. Male. Tomography, X-Ray Computed

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17583602.001).
  • [ISSN] 1646-0758
  • [Journal-full-title] Acta médica portuguesa
  • [ISO-abbreviation] Acta Med Port
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Portugal
  •  go-up   go-down


70. Liang J, Li G, Li Q, Liu G: [Remov ing the tumor of the cerebellopontile angle with microsurgery to treat the secondary trigeminal neuralgia]. Lin Chuang Er Bi Yan Hou Ke Za Zhi; 2005 May;19(10):446-8
MedlinePlus Health Information. consumer health - Trigeminal Neuralgia.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Remov ing the tumor of the cerebellopontile angle with microsurgery to treat the secondary trigeminal neuralgia].
  • OBJECTIVE: In order to explore the relationship between the tumor of cerebellopontile angle(CPA) and trigeminal neuralgia and to select the surgical treatment.
  • METHOD: With retrosigmoidal approach, the tumors of CPA were removed in 56 patients with the tumor of CPA and coexisting trigeminal neuralgia.
  • RESULT: All tumors were totally removed except one meningcoma which was removed by only 2/3 parts.
  • CONCLUSION: The pressure to the root of trigeminal nerve which comes from the tumor of CPA may be one of the etiologies of trigeminal neuralgia, which could be treated with the removal of the tumor of CPA.
  • The micrurgy of removing the tumor with retrosigmoidal approach is an ideal functional operation.
  • [MeSH-major] Cerebellar Neoplasms / surgery. Cerebellopontine Angle / surgery. Microsurgery. Trigeminal Neuralgia / surgery
  • [MeSH-minor] Adult. Aged. Female. Humans. Male. Middle Aged. Minimally Invasive Surgical Procedures. Neurosurgical Procedures / methods

  • Genetic Alliance. consumer health - Trigeminal neuralgia.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16108320.001).
  • [Journal-full-title] Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology
  • [ISO-abbreviation] Lin Chuang Er Bi Yan Hou Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  •  go-up   go-down


71. Brandes AA, Franceschi E: Neuro-oncology: Genetic variation in pediatric and adult brain tumors. Nat Rev Neurol; 2010 Dec;6(12):653-4
MedlinePlus Health Information. consumer health - Childhood Brain Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neuro-oncology: Genetic variation in pediatric and adult brain tumors.
  • Two new studies suggest that pediatric medulloblastomas and high-grade gliomas are genetically different from the same tumors in adults.
  • Age-dependent gene expression might affect tumor biology; therefore, therapies for adult medulloblastomas or gliomas might not produce the same clinical outcomes in pediatric patients, and vice versa.
  • [MeSH-major] Brain Neoplasms / genetics. Cerebellar Neoplasms / genetics. Gene Expression Profiling. Glioma / genetics. Medulloblastoma / genetics
  • [MeSH-minor] Adult. Child. Genetic Variation. Humans

  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21131914.001).
  • [ISSN] 1759-4766
  • [Journal-full-title] Nature reviews. Neurology
  • [ISO-abbreviation] Nat Rev Neurol
  • [Language] eng
  • [Publication-type] News
  • [Publication-country] England
  •  go-up   go-down


72. Tripathy K, Gouda KP, Das R, Rath J, Mohanty R: Cerebellar haemangioblastoma mimicking renal cell carcinoma--a case report. Indian J Pathol Microbiol; 2005 Jul;48(3):375-6
Genetic Alliance. consumer health - Renal cell carcinoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebellar haemangioblastoma mimicking renal cell carcinoma--a case report.
  • Haemangioblastoma is a rare benign vascular tumor commonly seen in the cerebellum.
  • Histology revealed a highly vascular tumor composed of clear cells in a lobular arrangement.
  • [MeSH-major] Carcinoma, Renal Cell / diagnosis. Cerebellar Neoplasms / diagnosis. Hemangioblastoma / diagnosis
  • [MeSH-minor] Adult. Cerebellum / pathology. Diagnosis, Differential. Humans. Male

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16761758.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  •  go-up   go-down


73. Choi KD, Kim JS, Kim HJ, Koo JW, Kim JH, Kim CY, Oh CW, Kee HJ: Hyperventilation-induced nystagmus in peripheral vestibulopathy and cerebellopontine angle tumor. Neurology; 2007 Sep 4;69(10):1050-9
Faculty of 1000. commentaries/discussion - See the articles recommended by F1000Prime's Faculty of more than 8,000 leading experts in Biology and Medicine. (subscription/membership/fee required).

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hyperventilation-induced nystagmus in peripheral vestibulopathy and cerebellopontine angle tumor.
  • OBJECTIVE: To determine the incidence and characteristics of hyperventilation-induced nystagmus (HIN) in cerebellopontine angle (CPA) tumors and unilateral peripheral vestibulopathy (UPV), and to elucidate differential contribution of hyperventilation to bring out vestibular asymmetry between acute and chronic phases of UPV.
  • METHODS: We recorded horizontal HIN in 33 patients with CPA tumors and 145 with UPV.
  • RESULTS: The incidence of HIN was higher in the CPA tumor than in the UPV group (82 vs 34%, p < 0.01) and was also higher in the acute than in the chronic UPV group (60 vs 21%, p < 0.01).
  • Furthermore, HIN was more commonly ipsilesional (i-HIN) in the CPA tumor than in the UPV group (52 vs 8%, p < 0.01) and more commonly ipsilesional in the acute than in the chronic UPV group (21 vs 1%, p < 0.01).
  • The patients with i-HIN and acoustic neuroma had a tendency to harbor smaller tumors and to have less severe caloric asymmetry.
  • Our study demonstrates that hyperventilation-induced nystagmus (HIN) beating to the side of reduced caloric response, hearing impairment, or abnormal auditory brainstem response responses may be a valuable sign for bedside detection of cerebellopontine angle (CPA) tumors.
  • CPA tumor should be a prime suspicion in patients with acute vertigo and ipsilesional HIN, especially when the vertigo accompanies hearing impairments.
  • [MeSH-major] Cerebellar Neoplasms / physiopathology. Cerebellopontine Angle / physiopathology. Hyperventilation / physiopathology. Nystagmus, Pathologic / physiopathology. Vestibular Neuronitis / physiopathology
  • [MeSH-minor] Adult. Aged. Evoked Potentials, Auditory, Brain Stem / physiology. Female. Humans. Male. Middle Aged

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [ErratumIn] Neurology. 2010 Nov 30;75(22):2046
  • (PMID = 17785675.001).
  • [ISSN] 1526-632X
  • [Journal-full-title] Neurology
  • [ISO-abbreviation] Neurology
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


74. Holland H, Koschny R, Krupp W, Meixensberger J, Bauer M, Schober R, Kirsten H, Ganten TM, Ahnert P: Cytogenetic and molecular biological characterization of an adult medulloblastoma. Cancer Genet Cytogenet; 2007 Oct 15;178(2):104-13
Genetic Alliance. consumer health - Medulloblastoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytogenetic and molecular biological characterization of an adult medulloblastoma.
  • Medulloblastoma is a malignant invasive embryonal tumor, occurring in children mainly.
  • It is rare in adults (<1% of adult brain tumors), and so comprehensive cytogenetic and molecular biological data on adult medulloblastomas are very limited.
  • We performed comprehensive cytogenetic analyses of an adult medulloblastoma, WHO grade IV, using trypsin-Giemsa staining (GTG-banding), multicolor fluorescence in situ hybridization (M-FISH), and locus-specific FISH, complemented by molecular karyotyping using high-density single nucleotide polymorphism (SNP) arrays.
  • [MeSH-major] Cerebellar Neoplasms / genetics. Medulloblastoma / genetics
  • [MeSH-minor] Adult. Child. Chromosome Aberrations. Chromosome Banding. Female. Flow Cytometry. Gene Expression Profiling. Gene Expression Regulation, Neoplastic. Humans. In Situ Hybridization, Fluorescence. Karyotyping. Matrix Metalloproteinase 2 / genetics. Phosphopyruvate Hydratase / genetics. Polymorphism, Single Nucleotide. Synaptophysin / genetics

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17954265.001).
  • [ISSN] 0165-4608
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Synaptophysin; EC 3.4.24.24 / Matrix Metalloproteinase 2; EC 4.2.1.11 / Phosphopyruvate Hydratase
  •  go-up   go-down


75. Huber JF, Bradley K, Spiegler B, Dennis M: Long-term neuromotor speech deficits in survivors of childhood posterior fossa tumors: effects of tumor type, radiation, age at diagnosis, and survival years. J Child Neurol; 2007 Jul;22(7):848-54

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term neuromotor speech deficits in survivors of childhood posterior fossa tumors: effects of tumor type, radiation, age at diagnosis, and survival years.
  • The cerebellum is important for the coordination of fluent speech.
  • The authors studied how childhood cerebellar tumors affect long-term neuromotor speech outcomes, including the relation between outcome and tumor type, radiation, age at diagnosis, and survival years.
  • Videotaped speech samples of child and adult long-term survivors of childhood cerebellar astrocytoma (nonradiated) and medulloblastoma (radiated) tumors and healthy controls were analyzed by 2 speech pathologists for ataxic dysarthria, dysfluency, and speech rate.
  • Ataxia varied with tumor type/radiation.
  • Dysfluency varied with a history of a posterior fossa tumor.
  • Speech rate varied with age and tumor type.
  • Adult controls were significantly faster than child controls, although adult tumor survivors were comparable to their child counterparts.
  • Adult controls had significantly faster speech rates than adult survivors of medulloblastoma tumors.
  • Ataxic dysarthric speech characteristics are more frequent in radiated survivors of medulloblastoma tumors than nonradiated survivors of astrocytoma tumors.
  • Dysfluent and slow speech occur in cerebellar tumor survivors, regardless of tumor type and radiation history.
  • Cerebellar tumors in childhood limit speech rate in adulthood.
  • [MeSH-major] Astrocytoma / complications. Cerebellar Neoplasms / complications. Dysarthria / etiology. Infratentorial Neoplasms / complications. Medulloblastoma / complications
  • [MeSH-minor] Adolescent. Adult. Age Factors. Analysis of Variance. Case-Control Studies. Child. Female. Follow-Up Studies. Humans. Male. Mutism / etiology. Radiotherapy / adverse effects. Reference Values. Speech Disorders / classification. Speech Disorders / etiology. Survivors. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17715277.001).
  • [ISSN] 0883-0738
  • [Journal-full-title] Journal of child neurology
  • [ISO-abbreviation] J. Child Neurol.
  • [Language] eng
  • [Grant] United States / NICHD NIH HHS / HD / P01 HD 35946
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Canada
  •  go-up   go-down


76. Marinovic T, Grahovac G, Habek M, Lambasa S, Tomac D: Simultaneous conus medullaris ependymoma and cerebellar astrocytoma in the same patient. Clin Neuropathol; 2009 May-Jun;28(3):173-6
Genetic Alliance. consumer health - Ependymoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Simultaneous conus medullaris ependymoma and cerebellar astrocytoma in the same patient.
  • Multiple primary tumors in the central nervous system of different histological cell types are uncommon.
  • We report a patient who had pilocytic astrocytoma in the cerebellum and ependymoma in the cauda equina region, occurring simultaneously.
  • The suggested mechanism of this association is that primitive multipotent cells might have been displaced in the different CNS areas and developed in different tumor cells.
  • Multiplicity of primary CNS tumors should be considered in certain occasions, when clinical symptoms and signs are pointing in that direction.
  • [MeSH-major] Astrocytoma / pathology. Cerebellar Neoplasms / pathology. Ependymoma / pathology. Neoplasms, Multiple Primary / pathology. Spinal Cord Neoplasms / pathology
  • [MeSH-minor] Adult. Cauda Equina / pathology. Cauda Equina / surgery. Female. Humans. Magnetic Resonance Imaging. Neurosurgical Procedures

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19537133.001).
  • [ISSN] 0722-5091
  • [Journal-full-title] Clinical neuropathology
  • [ISO-abbreviation] Clin. Neuropathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


77. Zhang J, Yang C, Gu HH, Liang WM: [Intraoperative cranial nerves monitoring under partial neuromuscular relaxation during cerebellopontine angle tumor resection]. Zhonghua Yi Xue Za Zhi; 2008 Jun 3;88(21):1481-4
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Intraoperative cranial nerves monitoring under partial neuromuscular relaxation during cerebellopontine angle tumor resection].
  • OBJECTIVE: To evaluate the efficacy of multiple cranial nerves monitoring under partial Seventy elective neuromuscular relaxation during cerebellopontine angle (CPA) tumor resection.
  • METHODS: patients undergoing CPA tumor resection via microneurosurgery were randomly allocated to 2 equal groups: Group FN receiving intraoperative facial nerve (NF) monitoring and Group MN receiving monitoring of multiple nerves: trigeminal nerve, glossopharyngeal nerve, accessory nerve or hypoglossal nerve other than the FN which were considered at risk by the neurosurgeon preoperatively.
  • Multiple cranial nerves combined with facial nerve monitoring seems unable to increase the short-term protective effects of nerve function after CPA tumor resection.
  • [MeSH-major] Cerebellar Neoplasms / physiopathology. Cerebellar Neoplasms / surgery. Cerebellopontine Angle / surgery. Cranial Nerves / physiopathology
  • [MeSH-minor] Adult. Feasibility Studies. Female. Humans. Male. Middle Aged. Monitoring, Intraoperative. Muscle Relaxation

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18953855.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Randomized Controlled Trial
  • [Publication-country] China
  •  go-up   go-down


78. Jang SY, Kong MH, Song KY, Frazee JG: Intracranial Metastases of Cervical Intramedullary Low-Grade Astrocytoma without Malignant Transformation in Adult. J Korean Neurosurg Soc; 2009 Jun;45(6):381-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intracranial Metastases of Cervical Intramedullary Low-Grade Astrocytoma without Malignant Transformation in Adult.
  • The first case of intracranial metastases of a cervical intramedullary low-grade astrocytoma without malignant transformation in adult is presented in this report.
  • MRI Scan demonstrated multiple small lesions in the cerebellar vermis and left hemisphere.
  • After suboccipital craniectomy and posterior cervical exposure, the small masses in the cerebellar vermis and hemispheres were excised to a large extent by guidance of an intraoperative navigation system.
  • The tumor at the cervical and brain lesions was classified as an astrocytoma (WHO grade II).

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Neurooncol. 2000 Dec;50(3):239-43 [11263503.001]
  • [Cites] J Clin Neurosci. 2001 Jul;8(4):374-7 [11437586.001]
  • [Cites] Spinal Cord. 2006 Dec;44(12):740-5 [16670687.001]
  • [Cites] Childs Nerv Syst. 2005 Jun;21(6):477-81 [15378329.001]
  • [Cites] Neurosurgery. 2005;56(1):191 [15617606.001]
  • [Cites] Med Pediatr Oncol. 1997 Dec;29(6):560-2 [9324344.001]
  • [Cites] Neurosurgery. 1997 Jan;40(1):141-51 [8971836.001]
  • [Cites] J Neurooncol. 1995;25(3):245-50 [8592175.001]
  • [Cites] J Neurosurg. 1995 Sep;83(3):480-5 [7666226.001]
  • [Cites] J Neurosurg. 1995 Oct;83(4):590-5 [7674006.001]
  • [Cites] J Neurosurg. 1995 Jul;83(1):67-71 [7782852.001]
  • [Cites] J Neurooncol. 1994;18(1):49-52 [8057134.001]
  • [Cites] Neurol Med Chir (Tokyo). 1992 May;32(5):281-4 [1378944.001]
  • [Cites] J Neurosurg. 1992 Sep;77(3):355-9 [1506881.001]
  • [Cites] J Neurosurg. 1988 Aug;69(2):295-300 [3392575.001]
  • [Cites] Cancer. 1982 Aug 15;50(4):732-5 [7093908.001]
  • [Cites] Br J Surg. 1975 Feb;62(2):92-5 [1115920.001]
  • [Cites] Pediatr Blood Cancer. 2004 Nov;43(6):629-32 [15390309.001]
  • [Cites] Childs Nerv Syst. 2004 Feb;20(2):114-8 [14762681.001]
  • [Cites] Cancer. 2003 Aug 1;98(3):554-61 [12879473.001]
  • [Cites] Curr Opin Neurol. 2001 Dec;14(6):679-82 [11723373.001]
  • [Cites] Surg Neurol. 2001 Jul;56(1):39-41 [11546571.001]
  • [Cites] J Neurosurg. 2006 Dec;105(6 Suppl):508-14 [17184088.001]
  • (PMID = 19609424.001).
  • [ISSN] 2005-3711
  • [Journal-full-title] Journal of Korean Neurosurgical Society
  • [ISO-abbreviation] J Korean Neurosurg Soc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2711238
  • [Keywords] NOTNLM ; Astrocytoma / Cranial metastases / Intramedullary / Spinal cord tumor
  •  go-up   go-down


79. Suyama K, Ujifuku K, Hirao T, Takahata H, Ito M, Yonekura M, Nagata I: Symptomatic syringomyelia associated with a dermoid tumor in the posterior fossa. Neurol Med Chir (Tokyo); 2009 Sep;49(9):434-7
MedlinePlus Health Information. consumer health - Syringomyelia.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Symptomatic syringomyelia associated with a dermoid tumor in the posterior fossa.
  • A 28-year-old female presented with a dermoid tumor in the posterior fossa associated with symptomatic syringomyelia.
  • Magnetic resonance (MR) imaging revealed cervical syringomyelia and tonsillar herniation concomitant with an intradural posterior fossa tumor which was totally removed.
  • The histological diagnosis was dermoid tumor.
  • Her symptoms subsided and MR imaging demonstrated complete resolution of the syrinx 12 months after tumor removal.
  • Benign congenital intracranial tumor may cause tonsillar herniation resulting in symptomatic cervical syringomyelia.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cranial Fossa, Posterior / pathology. Dermoid Cyst / pathology. Infratentorial Neoplasms / pathology. Syringomyelia / etiology
  • [MeSH-minor] Adult. Cerebrospinal Fluid Pressure / physiology. Decompression, Surgical. Encephalocele / etiology. Encephalocele / physiopathology. Female. Humans. Magnetic Resonance Imaging. Neurosurgical Procedures. Treatment Outcome

  • Genetic Alliance. consumer health - Syringomyelia.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19779293.001).
  • [ISSN] 1349-8029
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


80. Germanwala AV, Mai JC, Tomycz ND, Niranjan A, Flickinger JC, Kondziolka D, Lunsford LD: Boost Gamma Knife surgery during multimodality management of adult medulloblastoma. J Neurosurg; 2008 Feb;108(2):204-9
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Boost Gamma Knife surgery during multimodality management of adult medulloblastoma.
  • OBJECT: The aim of this paper was to determine prognostic factors for adult medulloblastoma treated with boost Gamma Knife surgery (GKS) following resection and craniospinal irradiation.
  • METHODS: The authors performed a retrospective analysis of 12 adult patients with histologically proven medulloblastoma or supratentorial primitive neuroectodermal tumor who between February 1991 and December 2004 underwent >or=1 sessions of GKS for posttreatment residual or recurrent tumors (6 tumors in each group).
  • Stereotactic radiosurgery was applied to residual and recurrent posterior fossa tumor as well as to foci of intracranial medulloblastoma metastases.
  • The mean GKS-treated tumor volume was 9.4 cm3 (range 0.5-39 cm3).
  • RESULTS: Following adjunctive radiosurgery, 5 patients had no evidence of tumor on magnetic resonance (MR) imaging, 3 patients had stable tumor burden on MR imaging, and 4 patients had evidence of tumor progression locally with or without intracranial metastases.
  • All patients with tumor progression died.
  • The majority of patients who achieved tumor eradication (80%) and tumor stabilization (67%) after GKS had residual tumor as the reason for their referral for GKS.
  • The best outcomes were attained in patients with residual disease who were younger, had smaller tumor volumes, had no evidence of metastatic disease, and had received higher cumulative GKS doses.
  • CONCLUSIONS: Single or multiple GKS sessions were a well-tolerated, feasible, and effective adjunctive treatment for posterior fossa residual or recurrent medulloblastoma as well as intracranial metastatic medulloblastoma in adult patients.
  • [MeSH-major] Cerebellar Neoplasms / surgery. Medulloblastoma / surgery. Neoadjuvant Therapy. Radiosurgery / methods
  • [MeSH-minor] Adult. Age Factors. Chemotherapy, Adjuvant. Cranial Irradiation. Disease Progression. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Recurrence, Local / radiotherapy. Neoplasm Recurrence, Local / surgery. Neoplasm, Residual. Neuroectodermal Tumors / radiotherapy. Neuroectodermal Tumors / surgery. Remission Induction. Retrospective Studies. Spine / radiation effects. Supratentorial Neoplasms / radiotherapy. Supratentorial Neoplasms / surgery. Survival Rate. Time Factors. Treatment Outcome

  • Genetic Alliance. consumer health - Medulloblastoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18240913.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


81. Mittal P, Gupta K, Saggar K, Kaur S: Adult medulloblastoma mimicking Lhermitte-Duclos disease: can diffusion weighted imaging help? Neurol India; 2009 Mar-Apr;57(2):203-5
Genetic Alliance. consumer health - Medulloblastoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adult medulloblastoma mimicking Lhermitte-Duclos disease: can diffusion weighted imaging help?
  • Lhermitte-Duclos disease, also known as dysplastic cerebellar gangliocytoma, is a rare cerebellar benign tumor with characteristic appearance of thickened cerebellar folia giving a laminated or striated appearance, quite diagnostic of the condition.
  • We had seen a patient with medulloblastoma with imaging findings suspicious for thickened cerebellar folia reminiscent of Lhermitte-Duclos disease.
  • [MeSH-major] Cerebellar Neoplasms / diagnosis. Diffusion Magnetic Resonance Imaging. Hamartoma Syndrome, Multiple / diagnosis. Medulloblastoma / diagnosis
  • [MeSH-minor] Contrast Media. Humans. Magnetic Resonance Imaging. Male. Young Adult

  • Genetic Alliance. consumer health - Lhermitte-Duclos disease.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19439857.001).
  • [ISSN] 0028-3886
  • [Journal-full-title] Neurology India
  • [ISO-abbreviation] Neurol India
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Contrast Media
  •  go-up   go-down


82. Ertas G, Ucer AR, Altundag MB, Durmus S, Calikoglu T, Ozbagi K, Abanuz H, Altundag K, Demirkasimoglu A: Medulloblastoma/primitive neuroectodermal tumor in adults: prognostic factors and treatment results: a single-center experience from Turkey. Med Oncol; 2008;25(1):69-72
Genetic Alliance. consumer health - Medulloblastoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Medulloblastoma/primitive neuroectodermal tumor in adults: prognostic factors and treatment results: a single-center experience from Turkey.
  • We performed retrospective review of 29 adult patients with cerebellar medulloblastoma/primitive neuroectodermal tumor (PNET) who received craniospinal radiotherapy in Ankara Oncology Hospital between years 2000 and 2005.
  • In conclusion, adult patients with PNET have worse survival rates than patients with medulloblastoma, like in childhood patients.
  • [MeSH-major] Cerebellar Neoplasms / mortality. Medulloblastoma / mortality
  • [MeSH-minor] Adult. Female. Humans. Male. Neoplasm Recurrence, Local. Prognosis. Survival Rate. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Int J Radiat Oncol Biol Phys. 2003 Nov 1;57(3):755-61 [14529781.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1995 Jul 15;32(4):1145-52 [7607936.001]
  • [Cites] J Neurosurg. 1978 May;48(5):741-6 [641553.001]
  • [Cites] Cancer. 1994 Oct 15;74(8):2352-60 [7922986.001]
  • [Cites] Neurosurgery. 2000 Sep;47(3):623-31; discussion 631-2 [10981749.001]
  • [Cites] J Neurol. 2005 Mar;252(3):291-9 [16189725.001]
  • [Cites] J Neurosurg. 1981 Sep;55(3):376-81 [6267228.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2006 Feb 1;64(2):402-7 [16198067.001]
  • [Cites] Cancer J Sci Am. 1997 Jul-Aug;3(4):238-45 [9263630.001]
  • [Cites] Eur J Cancer. 2005 Jun;41(9):1304-10 [15869875.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1995 Jul 15;32(4):951-7 [7607969.001]
  • [Cites] J Neurooncol. 1985;3(1):23-33 [2987425.001]
  • [Cites] Neuro Oncol. 2001 Jul;3(3):167-73 [11465397.001]
  • (PMID = 18188718.001).
  • [ISSN] 1357-0560
  • [Journal-full-title] Medical oncology (Northwood, London, England)
  • [ISO-abbreviation] Med. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


83. Neder L, Scheithauer BW, Turel KE, Arnesen MA, Ketterling RP, Jin L, Moynihan TJ, Giannini C, Meyer FB: Desmoplastic small round cell tumor of the central nervous system: report of two cases and review of the literature. Virchows Arch; 2009 Apr;454(4):431-9
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic small round cell tumor of the central nervous system: report of two cases and review of the literature.
  • Desmoplastic small round cell tumor (DSRCT) is a malignant tumor often involving the abdominal and/or pelvic peritoneum.
  • Patient 2, a 39-year-old man, presented with cerebellar and CPA lesions as well as spinal leptomeningeal deposits.
  • Although rare, DSRCT warrants consideration in the differential diagnosis of "malignant small blue cell tumors" of the CNS.
  • [MeSH-major] Carcinoma, Small Cell / pathology. Cerebellar Neoplasms / pathology. Cerebellopontine Angle / pathology
  • [MeSH-minor] Adult. Humans. Immunohistochemistry. In Situ Hybridization, Fluorescence. Magnetic Resonance Imaging. Male. Oncogene Proteins, Fusion / genetics. Reverse Transcriptase Polymerase Chain Reaction

  • Genetic Alliance. consumer health - Desmoplastic Small Round Cell Tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Am J Surg Pathol. 1992 Oct;16(10):998-1006 [1384373.001]
  • [Cites] J Neuropathol Exp Neurol. 2002 Mar;61(3):215-25; discussion 226-9 [11895036.001]
  • [Cites] Am J Surg Pathol. 1998 Nov;22(11):1303-13 [9808123.001]
  • [Cites] Am J Surg Pathol. 1990 Jul;14(7):633-42 [2356923.001]
  • [Cites] J Clin Oncol. 1998 Sep;16(9):3028-36 [9738572.001]
  • [Cites] Diagn Mol Pathol. 1998 Feb;7(1):24-8 [9646031.001]
  • [Cites] Am J Surg Pathol. 1996 Jan;20(1):112-7 [8540602.001]
  • [Cites] Hum Pathol. 1997 Apr;28(4):502-9 [9104953.001]
  • [Cites] Cancer Cell. 2002 Dec;2(6):497-505 [12498718.001]
  • [Cites] Arch Pathol Lab Med. 2006 May;130(5):728-32 [16683894.001]
  • [Cites] Hum Pathol. 1992 Apr;23(4):454-64 [1563748.001]
  • [Cites] Arch Pathol Lab Med. 1989 Sep;113(9):1019-29 [2505732.001]
  • [Cites] Am J Surg Pathol. 2002 Jul;26(7):823-35 [12131150.001]
  • [Cites] Am J Surg Pathol. 1989 May;13(5):413-21 [2469334.001]
  • [Cites] Nature. 1990 Jul 12;346(6280):194-7 [2164159.001]
  • [Cites] Am J Surg Pathol. 1995 Jun;19(6):659-65 [7755152.001]
  • [Cites] Diagn Mol Pathol. 2005 Mar;14(1):23-8 [15714060.001]
  • [Cites] Am J Surg Pathol. 1999 Nov;23(11):1408-13 [10555010.001]
  • [Cites] Cancer Genet Cytogenet. 1993 Aug;69(1):17-21 [8374894.001]
  • [Cites] Exp Cell Res. 2001 Mar 10;264(1):74-99 [11237525.001]
  • [Cites] Acta Cytol. 1995 Mar-Apr;39(2):377-8 [7887076.001]
  • [Cites] J Surg Oncol. 1999 Aug;71(4):269-72 [10440769.001]
  • [Cites] J Neurosurg. 1996 Jul;85(1):56-65 [8683283.001]
  • [Cites] Acta Neuropathol. 2007 Aug;114(2):97-109 [17618441.001]
  • [Cites] Acta Cytol. 1993 Jan-Feb;37(1):77-82 [7679537.001]
  • [Cites] Semin Diagn Pathol. 1996 Aug;13(3):204-12 [8875710.001]
  • [Cites] Proc Natl Acad Sci U S A. 1995 Feb 14;92(4):1028-32 [7862627.001]
  • [Cites] Am J Surg Pathol. 2004 May;28(5):644-50 [15105654.001]
  • [Cites] Virchows Arch. 1998 Feb;432(2):135-41 [9504858.001]
  • [Cites] Mod Pathol. 1999 Jul;12(7):729-34 [10430278.001]
  • [Cites] Ultrastruct Pathol. 2000 Sep-Oct;24(5):333-7 [11071572.001]
  • [Cites] Hum Pathol. 1999 Apr;30(4):430-5 [10208465.001]
  • [Cites] Pediatr Pathol. 1989;9(2):177-83 [2473463.001]
  • [Cites] Virchows Arch A Pathol Anat Histopathol. 1991;418(3):207-14 [1900966.001]
  • [Cites] Cancer Res. 1994 Jun 1;54(11):2837-40 [8187063.001]
  • [Cites] Am J Surg Pathol. 1991 Jun;15(6):499-513 [1709557.001]
  • [Cites] Gynecol Oncol. 2000 Oct;79(1):124-8 [11006044.001]
  • [Cites] Arch Pathol Lab Med. 2002 Oct;126(10):1226-8 [12296765.001]
  • [Cites] Semin Cancer Biol. 2005 Jun;15(3):197-205 [15826834.001]
  • [Cites] Semin Diagn Pathol. 2003 Feb;20(1):25-45 [12693673.001]
  • [Cites] Pediatr Blood Cancer. 2008 Oct;51(4):545-8 [18561179.001]
  • (PMID = 19263077.001).
  • [ISSN] 1432-2307
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / EWS1-WT1 fusion protein, human; 0 / Oncogene Proteins, Fusion
  •  go-up   go-down


84. Volodin AV, Nemirovskiĭ VB: [Emergency abdominal delivery and ventriculoperitoneal bypass in pregnant females with brain tumor]. Anesteziol Reanimatol; 2007 Nov-Dec;(6):57-9
MedlinePlus Health Information. consumer health - Tumors and Pregnancy.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Emergency abdominal delivery and ventriculoperitoneal bypass in pregnant females with brain tumor].
  • The pregnant woman at gestational weeks 36-37 was found to have a brain tumor complicated by obstructive hydrocephalus and dislocation syndrome.
  • [MeSH-major] Cerebellar Neoplasms / surgery. Cesarean Section. Emergency Medical Services. Pregnancy Complications, Neoplastic / surgery. Ventriculoperitoneal Shunt
  • [MeSH-minor] Adult. Female. Gestational Age. Humans. Infant, Newborn. Pregnancy. Pregnancy Outcome. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Cesarean Section.
  • MedlinePlus Health Information. consumer health - Emergency Medical Services.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18326262.001).
  • [ISSN] 0201-7563
  • [Journal-full-title] Anesteziologiia i reanimatologiia
  • [ISO-abbreviation] Anesteziol Reanimatol
  • [Language] rus
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
  •  go-up   go-down


85. Gupta A, Ahmad FU, Sharma MC, Garg A, Mehta VS: Cerebellopontine angle meningeal melanocytoma: a rare tumor in an uncommon location. Case report. J Neurosurg; 2007 Jun;106(6):1094-7
MedlinePlus Health Information. consumer health - Melanoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cerebellopontine angle meningeal melanocytoma: a rare tumor in an uncommon location. Case report.
  • Meningeal melanocytomas are uncommon intracranial tumors and their occurrence at the cerebellopontine angle (CPA) is extremely rare.
  • The authors describe the case of a 58-year-old woman who presented with a left CPA tumor; on the basis of histopathological studies after resection, a diagnosis of meningeal melanocytoma was reached.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cerebellar Neoplasms / surgery. Cerebellopontine Angle / pathology. Cerebellopontine Angle / surgery. Melanoma / pathology. Melanoma / surgery. Meningioma / pathology. Meningioma / surgery
  • [MeSH-minor] Adult. Female. Humans. Magnetic Resonance Imaging. Melanins / metabolism. Neurosurgical Procedures

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17564187.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Melanins
  •  go-up   go-down


86. Pang JC, Chang Q, Chung YF, Teo JG, Poon WS, Zhou LF, Kong X, Ng HK: Epigenetic inactivation of DLC-1 in supratentorial primitive neuroectodermal tumor. Hum Pathol; 2005 Jan;36(1):36-43
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epigenetic inactivation of DLC-1 in supratentorial primitive neuroectodermal tumor.
  • Supratentorial primitive neuroectodermal tumors (SPNETs) and medulloblastomas (MBs) are histologically similar intracranial tumors found in different anatomic locations of the brain.
  • The aim of this study was to evaluate whether DLC-1, a newly identified tumor-suppressor gene on chromosome 8p22, is involved in the tumorigenesis of MBs and the histologically similar SPNETs.
  • We first assessed for alterations of gene expression in microdissected tumors and detected lack of DLC-1 transcript in 1 of 9 MBs (case M44) and 1 of 3 SPNETs (case M1).
  • Neither somatic base substitutions nor homozygous deletion were found in tumors without DLC-1 transcript.
  • [MeSH-major] Epigenesis, Genetic. Gene Silencing. Neuroectodermal Tumors, Primitive / genetics. Supratentorial Neoplasms / genetics. Tumor Suppressor Proteins / genetics
  • [MeSH-minor] Adolescent. Adult. Base Sequence. Cell Line, Tumor. Cerebellar Neoplasms / genetics. Child. Child, Preschool. Chromosomes, Human, Pair 8 / genetics. CpG Islands. DNA Methylation. Female. GTPase-Activating Proteins. Gene Expression Regulation, Neoplastic. Humans. Infant. Lasers. Loss of Heterozygosity. Male. Medulloblastoma / genetics. Microdissection. Molecular Sequence Data. Promoter Regions, Genetic. Reverse Transcriptase Polymerase Chain Reaction

  • Genetic Alliance. consumer health - Supratentorial primitive neuroectodermal tumor.
  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15712180.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DLC1 protein, human; 0 / GTPase-Activating Proteins; 0 / Tumor Suppressor Proteins
  •  go-up   go-down


87. Luan S, Zhuang D, Sun L, Huang FP: Rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle: Case report and review of literature. Clin Neurol Neurosurg; 2010 May;112(4):362-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle: Case report and review of literature.
  • Rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle has been identified as a novel and distinctive type of primary central nervous system neoplasm.
  • In this report, we present a case with RGNT arising from the right cerebellar hemisphere.
  • RGNT of the fourth ventricle is a rare, benign tumor with an excellent prognosis.
  • [MeSH-major] Cerebral Ventricle Neoplasms / pathology. Fourth Ventricle / pathology. Glioma / pathology. Rosette Formation
  • [MeSH-minor] Adult. Cerebellar Neoplasms / pathology. Cerebellum / pathology. Female. Humans. Magnetic Resonance Imaging. Neurosurgical Procedures. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Crown Copyright 2010. Published by Elsevier B.V. All rights reserved.
  • (PMID = 20133047.001).
  • [ISSN] 1872-6968
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  •  go-up   go-down


88. Howes TL, Buatti JM, Kirby PA, Carlisle TL, Ryken TC: Radiation induced adult medulloblastoma: a case report. J Neurooncol; 2006 Nov;80(2):191-4
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radiation induced adult medulloblastoma: a case report.
  • Adult medulloblastoma is a rare intracranial tumor.
  • Our patient is a 61 year old woman treated with cranial irradiation 15 years previously for a low grade astrocytoma in the left posterior temporal lobe that was recently diagnosed with medulloblastoma in the right cerebellum.
  • This is the first reported case of radiation induced adult medulloblastoma.
  • [MeSH-major] Cerebellar Neoplasms / etiology. Medulloblastoma / etiology. Neoplasms, Radiation-Induced / pathology
  • [MeSH-minor] Astrocytoma / radiotherapy. Brain Neoplasms / radiotherapy. Craniotomy. Female. Humans. Magnetic Resonance Imaging. Middle Aged. Neurosurgical Procedures. Temporal Lobe / pathology

  • Genetic Alliance. consumer health - Medulloblastoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Neurol Neurosurg Psychiatry. 2004 Jun;75 Suppl 2:ii2-11 [15146033.001]
  • [Cites] Tumori. 2003 Jul-Aug;89(4):443-7 [14606653.001]
  • [Cites] Cancer. 1994 Oct 15;74(8):2352-60 [7922986.001]
  • [Cites] J Neurooncol. 1997 Nov;35(2):169-76 [9266455.001]
  • [Cites] Health Phys. 2003 Jul;85(1):43-6 [12852470.001]
  • [Cites] Neurosurgery. 2000 Sep;47(3):623-31; discussion 631-2 [10981749.001]
  • [Cites] Cancer Treat Rev. 1999 Feb;25(1):3-12 [10212586.001]
  • [Cites] J Clin Oncol. 2002 May 1;20(9):2267-76 [11980997.001]
  • [Cites] Surg Neurol. 2003 Jul;60(1):60-7; discussion 67 [12865017.001]
  • [Cites] J Clin Oncol. 2002 May 1;20(9):2223-4 [11980992.001]
  • [Cites] Lancet Neurol. 2003 Jul;2(7):395-403 [12849117.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1996 Oct 1;36(3):549-56 [8948338.001]
  • [Cites] Cancer. 1948 May;1(1):3-29 [18867438.001]
  • (PMID = 16710747.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


89. Baillieux H, De Smet HJ, Lesage G, Paquier P, De Deyn PP, Mariën P: Neurobehavioral alterations in an adolescent following posterior fossa tumor resection. Cerebellum; 2006;5(4):289-95

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neurobehavioral alterations in an adolescent following posterior fossa tumor resection.
  • The posterior fossa syndrome (PFS) consists of a variety of symptoms, including cerebellar mutism, behavioral disturbances and personality changes.
  • We report longitudinal clinical, neuroradiological and neurobehavioral findings in a 19-year-old left-handed patient, diagnosed with attentional deficit hyperactivity disorder (ADHD) at the age of 12, who underwent posterior fossa tumor resection.
  • Although the patient did not develop cerebellar mutism after surgery, marked apathy and emotional indifference, urinary retention, eye-lid apraxia and visual hallucinosis became apparent after a brief interval of normal functioning.
  • Long-term follow-up investigations revealed subtle, but significant cognitive and affective deficits, resembling the cerebellar cognitive affective syndrome in adults.
  • As demonstrated by functional neuroimaging studies with SPECT, symptoms were associated with perfusional deficits in the anatomoclinically suspected supratentorial regions, reflecting the distant impact of the cerebellum on cognitive and affective functions.
  • [MeSH-major] Behavior. Infratentorial Neoplasms / psychology. Infratentorial Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Cognition. Functional Laterality. Gait Ataxia / etiology. Humans. Magnetic Resonance Imaging. Male. Memory. Radiography. Tomography, Emission-Computed, Single-Photon

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Pediatr Neurosurg. 1991-1992;17(4):196-8 [1822134.001]
  • [Cites] J Neuropsychiatry Clin Neurosci. 2004 Fall;16(4):443-5 [15616170.001]
  • [Cites] Neurology. 1998 Apr;50(4):1087-93 [9566399.001]
  • [Cites] Cortex. 1998 Apr;34(2):279-87 [9606593.001]
  • [Cites] J Neurosurg. 1962 Jul;19:568-76 [14492326.001]
  • [Cites] Childs Nerv Syst. 1998 Mar;14 (3):114-9 [9579866.001]
  • [Cites] Clin Neurol Neurosurg. 1997 May;99(2):130-4 [9213058.001]
  • [Cites] Clin Neurol Neurosurg. 2006 Jul;108(5):518-22 [16055261.001]
  • [Cites] J Neurol. 1996 Aug;243(8):594-8 [8865026.001]
  • [Cites] Neurology. 1958 Mar;8(3):238-42 [13517492.001]
  • [Cites] J Neurol Neurosurg Psychiatry. 1999 Dec;67(6):755-7 [10567492.001]
  • [Cites] J Pediatr Oncol Nurs. 1995 Oct;12(4):181-7 [7495523.001]
  • [Cites] Childs Nerv Syst. 1998 Sep;14 (9):460-2 [9808255.001]
  • [Cites] Semin Neurol. 1990 Sep;10(3):287-94 [2259807.001]
  • [Cites] Cereb Cortex. 2006 Jul;16(7):916-28 [16207933.001]
  • [Cites] Brain Lang. 1998 Dec;65(3):447-67 [9843614.001]
  • [Cites] Pediatr Hematol Oncol. 2001 Oct-Nov;18(7):423-6 [11594705.001]
  • [Cites] J Neurooncol. 2000 May;48(1):75-81 [11026700.001]
  • [Cites] Pediatr Neurosurg. 2003 Mar;38(3):122-7 [12601236.001]
  • [Cites] Childs Nerv Syst. 2002 Jul;18(6-7):318-25 [12172939.001]
  • [Cites] Brain. 2000 May;123 ( Pt 5):1041-50 [10775548.001]
  • [Cites] Pediatr Neurol. 2005 Feb;32(2):127-30 [15664775.001]
  • [Cites] Neurosurgery. 1995 Nov;37(5):885-93 [8559336.001]
  • [Cites] Brain. 2000 May;123 ( Pt 5):1051-61 [10775549.001]
  • [Cites] Brain. 1998 Apr;121 ( Pt 4):561-79 [9577385.001]
  • [Cites] Br J Neurosurg. 2001 Feb;15(1):47-50 [11303661.001]
  • [Cites] Brain Lang. 2001 Dec;79(3):580-600 [11781058.001]
  • [Cites] J Neurol. 2004 Aug;251(8):963-72 [15316801.001]
  • [Cites] Neurosurgery. 1998 Feb;42(2):253-6; discussion 256-7 [9482175.001]
  • [Cites] Eur Arch Psychiatry Clin Neurosci. 2002 Oct;252(5):219-25 [12451463.001]
  • [Cites] J Neurol Neurosurg Psychiatry. 2002 Aug;73(2):191-4 [12122182.001]
  • [Cites] Arch Neurol. 1985 Jul;42(7):697-8 [4015467.001]
  • [Cites] Int Rev Neurobiol. 1997;41:411-32 [9378600.001]
  • [Cites] Pediatr Neurosurg. 2005 Jan-Feb;41(1):15-21 [15886508.001]
  • [Cites] Acta Neurol Belg. 1992;92 (4):228-33 [1441901.001]
  • (PMID = 17134992.001).
  • [ISSN] 1473-4222
  • [Journal-full-title] Cerebellum (London, England)
  • [ISO-abbreviation] Cerebellum
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


90. Herrlinger U, Steinbrecher A, Rieger J, Hau P, Kortmann RD, Meyermann R, Schabet M, Bamberg M, Dichgans J, Bogdahn U, Weller M: Adult medulloblastoma: prognostic factors and response to therapy at diagnosis and at relapse. J Neurol; 2005 Mar;252(3):291-9
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adult medulloblastoma: prognostic factors and response to therapy at diagnosis and at relapse.
  • Adult medulloblastoma is a rare tumor with few retrospective studies published so far.
  • This study reports therapy and outcome in all adult (>or=16 years old) medulloblastoma (n=34) and supratentorial primitive neuroectodermal tumor (PNET) patients (n=2) treated in 2 neuro-oncological centers between 1976 and 2002.
  • In conclusion, adjuvant chemotherapy may prolong survival in adult medulloblastoma patients.
  • [MeSH-major] Cerebellar Neoplasms / therapy. Medulloblastoma / therapy
  • [MeSH-minor] Adolescent. Adult. Aged. Analysis of Variance. Combined Modality Therapy. Demography. Disease Progression. Disease-Free Survival. Dose-Response Relationship, Radiation. Drug Therapy / methods. Female. Humans. Male. Middle Aged. Radiotherapy, High-Energy / methods. Recurrence. Regression Analysis. Retrospective Studies. Risk Factors. Time Factors. Treatment Outcome

  • Genetic Alliance. consumer health - Medulloblastoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Int J Radiat Oncol Biol Phys. 1990 Apr;18(4):763-72 [2323967.001]
  • [Cites] J Clin Oncol. 1999 Mar;17(3):832-45 [10071274.001]
  • [Cites] Int J Cancer. 1999 Mar 1;80(5):689-92 [10048968.001]
  • [Cites] J Neurosurg. 1990 Apr;72(4):572-82 [2319316.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1995 Jul 15;32(4):1145-52 [7607936.001]
  • [Cites] Eur J Cancer. 1990 Apr;26(4):464-9 [2141512.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2002 Nov 1;54(3):855-60 [12377339.001]
  • [Cites] Cancer. 1994 Oct 15;74(8):2352-60 [7922986.001]
  • [Cites] Neurosurgery. 2000 Sep;47(3):623-31; discussion 631-2 [10981749.001]
  • [Cites] J Clin Oncol. 1990 Jul;8(7):1277-80 [2358840.001]
  • [Cites] Cancer Treat Rev. 1999 Feb;25(1):3-12 [10212586.001]
  • [Cites] Neuro Oncol. 2001 Jan;3(1):29-34 [11305414.001]
  • [Cites] Neurosurgery. 1996 Feb;38(2):265-71 [8869053.001]
  • [Cites] J Clin Oncol. 2002 Feb 1;20(3):842-9 [11821469.001]
  • [Cites] Cancer. 1999 Jul 1;86(1):142-8 [10391574.001]
  • [Cites] J Clin Oncol. 1999 Jul;17(7):2127-36 [10561268.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2000 Jun 1;47(3):573-84 [10837938.001]
  • [Cites] Bone Marrow Transplant. 2002 Nov;30(9):565-9 [12407430.001]
  • [Cites] Neurology. 1995 Mar;45(3 Pt 1):440-2 [7898692.001]
  • [Cites] J Clin Oncol. 2003 Apr 15;21(8):1581-91 [12697884.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2000 Jan 15;46(2):269-79 [10661332.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1995 Jul 15;32(4):951-7 [7607969.001]
  • [Cites] J Clin Oncol. 1998 Jan;16(1):222-8 [9440746.001]
  • [Cites] J Neurosurg. 1994 Nov;81(5):690-8 [7931615.001]
  • [Cites] J Clin Oncol. 2000 Aug;18(16):3004-11 [10944134.001]
  • [Cites] Med Pediatr Oncol. 2002 Aug;39(2):99-108 [12116057.001]
  • [Cites] Radiology. 1969 Dec;93(6):1351-9 [4983156.001]
  • (PMID = 16189725.001).
  • [ISSN] 0340-5354
  • [Journal-full-title] Journal of neurology
  • [ISO-abbreviation] J. Neurol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


91. Mekni A, Chelly I, Haouet S, Zitouna M, Kchir N: [Malignant cerebellar ganglioglioma. A case report and review of the literature]. Neurochirurgie; 2006 Jun;52(2-3 Pt 1):119-22
Genetic Alliance. consumer health - Ganglioglioma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Malignant cerebellar ganglioglioma. A case report and review of the literature].
  • Ganglioglioma is usually a well differentiated slowly growing mixed neuronal and glial neoplasm corresponding to WHO grade I or II.
  • We report a case of a 25-year-old woman with a family history of neurofibromatosis who presented initially with a World Health Organization grade IV anaplastic ganglioglioma (a mixed ganglion cell multiform tumor glioblastoma).
  • Immunohistochemical analysis clearly distinguished the two tumor cell populations.
  • It also documents the aggressive biologic behavior of this complex neoplasm.
  • [MeSH-major] Ganglioglioma / pathology. Infratentorial Neoplasms / pathology
  • [MeSH-minor] Adult. Fatal Outcome. Female. Humans. Immunohistochemistry. Neurofibromatoses / genetics. Tomography, X-Ray Computed

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16840971.001).
  • [ISSN] 0028-3770
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  •  go-up   go-down


92. Skalova A, Síma R, Bohus P, Curík R, Lukás J, Michal M: Endolymphatic sac tumor (aggressive papillary tumor of middle ear and temporal bone): report of two cases with analysis of the VHL gene. Pathol Res Pract; 2008;204(8):599-606
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endolymphatic sac tumor (aggressive papillary tumor of middle ear and temporal bone): report of two cases with analysis of the VHL gene.
  • Endolymphatic sac tumor (Heffner tumor) (ELST) is a very rare nonmetastasizing, locally aggressive low-grade adenocarcinoma of endolymphatic sac origin, which is linked to von-Hippel-Lindau disease (VHLD).
  • The tissues obtained from Heffner tumor and cerebellar hemangioblastoma from the patient with inherited VHLD possess a point mutation in exon 1 of VHL gene.
  • [MeSH-major] Adenocarcinoma / genetics. Ear Neoplasms / genetics. Ear, Middle / pathology. Endolymphatic Sac / pathology. Gene Expression Regulation, Neoplastic. Skull Neoplasms / genetics. Temporal Bone / pathology. Von Hippel-Lindau Tumor Suppressor Protein / genetics. von Hippel-Lindau Disease / genetics
  • [MeSH-minor] Adult. Aged. DNA Mutational Analysis. Exons. Female. Genetic Predisposition to Disease. Humans. Introns. Neoplasm Invasiveness. Pedigree. Point Mutation

  • MedlinePlus Health Information. consumer health - Von Hippel-Lindau Disease.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18423895.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] EC 6.3.2.19 / VHL protein, human; EC 6.3.2.19 / Von Hippel-Lindau Tumor Suppressor Protein
  •  go-up   go-down


93. Comincini S, Ferrara V, Arias A, Malovini A, Azzalin A, Ferretti L, Benericetti E, Cardarelli M, Gerosa M, Passarin MG, Turazzi S, Bellazzi R: Diagnostic value of PRND gene expression profiles in astrocytomas: relationship to tumor grades of malignancy. Oncol Rep; 2007 May;17(5):989-96
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diagnostic value of PRND gene expression profiles in astrocytomas: relationship to tumor grades of malignancy.
  • It is abundant in testis and, unlike PRNP, it is expressed at low levels in the adult central nervous system (CNS).
  • Besides, doppel overexpression correlates with some prion-disease pathological features, such as ataxia and death of cerebellar neurons.
  • Recently, ectopic expression of doppel was found in two different tumor types, specifically in glial and haematological cancers.
  • [MeSH-major] Astrocytoma / genetics. Brain Neoplasms / genetics. Prions / biosynthesis
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Algorithms. Child. Cluster Analysis. Female. GPI-Linked Proteins. Gene Expression Profiling. Glioblastoma / genetics. Glioblastoma / metabolism. Glioblastoma / pathology. Humans. Male. Middle Aged. Prognosis

  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • MedlinePlus Health Information. consumer health - Childhood Brain Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17390034.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / GPI-Linked Proteins; 0 / PRND protein, human; 0 / Prions
  •  go-up   go-down


94. Pimentel J, Resende M, Vaz A, Reis AM, Campos A, Carvalho H, Honavar M: Rosette-forming glioneuronal tumor: pathology case report. Neurosurgery; 2008 May;62(5):E1162-3; discussion E1163

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rosette-forming glioneuronal tumor: pathology case report.
  • OBJECTIVE: Rosette-forming glioneuronal tumor is a newly described mixed glial and neuronal tumor.
  • METHODS: Patients were surgically treated, and tumors were diagnosed by light microscopy and immunohistochemistry using the avidin-biotin complex method.
  • Magnetic resonance imaging revealed a right paramedian cerebellar cystic and nodular mass and a separate nodule in the vermis, which were excised gross totally with no morbidity.
  • Microscopic examination showed neuroepithelial tumors composed of neurocytic cells focally forming well-defined rosettes that were immunopositive for neuronal markers and of elongated, glial fibrillary acidic protein-immunoreactive astrocytes.
  • Eighteen rosette-forming glioneuronal tumors were identified with the literature search.
  • CONCLUSION: These are tumors of young adulthood (range, 12-59 yr) usually in or close to the fourth ventricle.
  • They are composed of neurocytic and glial elements, probably arising from a common progenitor in the subependymal plate, and need to be differentiated from a variety of glioneuronal tumors.
  • [MeSH-major] Cerebral Ventricle Neoplasms / pathology. Fourth Ventricle / pathology. Ganglioglioma / pathology
  • [MeSH-minor] Adult. Female. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Middle Aged. Neurosurgical Procedures

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18580784.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


95. Guan YG, Wang TH, Ni W, Li L, Lu YC, Gao ZY: [Distribution of Fas and FasL in the central nervous system of adult rhesus]. Sichuan Da Xue Xue Bao Yi Xue Ban; 2005 May;36(3):322-4
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Distribution of Fas and FasL in the central nervous system of adult rhesus].
  • OBJECTIVE: To investigate the distribution of Fas and FasL in the CNS of adult rhesus.
  • FasL immunopositive neurons were observed in cerebral cortex, especially in pyramidal neurons of lamina I and V, cerebellar nuclei, diencephalon, and brain stem nuclei involving pontine nucleus, vestibular nucleus, cochlear nucleus, spinal nucleus of trigeminal nerve, hypoglossal nucleus, nucleus ambiguous and reticular formation.
  • [MeSH-major] Antigens, CD95 / metabolism. Brain Chemistry. Membrane Glycoproteins / metabolism. Tumor Necrosis Factors / metabolism

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15931857.001).
  • [ISSN] 1672-173X
  • [Journal-full-title] Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
  • [ISO-abbreviation] Sichuan Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, CD95; 0 / Fas Ligand Protein; 0 / Membrane Glycoproteins; 0 / Tumor Necrosis Factors
  •  go-up   go-down


96. Cheng YC, Lirng JF, Chang FC, Guo WY, Teng MM, Chang CY, Wong TT, Ho DM: Neuroradiological findings in atypical teratoid/rhabdoid tumor of the central nervous system. Acta Radiol; 2005 Feb;46(1):89-96
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neuroradiological findings in atypical teratoid/rhabdoid tumor of the central nervous system.
  • PURPOSE: To evaluate the computed tomography (CT) and magnetic resonance imaging (MRI) findings of atypical teratoid tumor/rhabdoid tumor (AT/RT) of the central nervous system (CNS).
  • RESULTS: AT/RT was located in the cerebellum in 15 cases.
  • CONCLUSION: Most cases of AT/RT are located in the cerebellum.
  • However, AT/RT should still remain in the differential diagnosis of brain tumors in young children, especially those located in the cerebellar hemisphere and with eccentric cysts.
  • [MeSH-major] Central Nervous System Neoplasms / pathology. Central Nervous System Neoplasms / radiography. Rhabdoid Tumor / pathology. Rhabdoid Tumor / radiography. Teratoma / pathology. Teratoma / radiography
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Diagnosis, Differential. Female. Humans. Infant. Magnetic Resonance Imaging. Male. Prognosis. Retrospective Studies. Survival Rate. Tomography, X-Ray Computed

  • Genetic Alliance. consumer health - Rhabdoid tumor.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15841745.001).
  • [ISSN] 0284-1851
  • [Journal-full-title] Acta radiologica (Stockholm, Sweden : 1987)
  • [ISO-abbreviation] Acta Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Sweden
  •  go-up   go-down


97. Comincini S, Chiarelli LR, Zelini P, Del Vecchio I, Azzalin A, Arias A, Ferrara V, Rognoni P, Dipoto A, Nano R, Valentini G, Ferretti L: Nuclear mRNA retention and aberrant doppel protein expression in human astrocytic tumor cells. Oncol Rep; 2006 Dec;16(6):1325-32
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nuclear mRNA retention and aberrant doppel protein expression in human astrocytic tumor cells.
  • It is abundant in testis and, unlike PrP, it is expressed at low levels in the adult central nervous system (CNS).
  • Besides, Dpl overexpression correlates with some prion-disease pathological features, such as ataxia and death of cerebellar neurons.
  • Recently, ectopic expression of doppel was found in two different tumor types, specifically in glial and haematological cancers.
  • Immunohistochemistry experiments demonstrated that Dpl was mainly localised in the cytoplasm of the astrocytic tumor cells, and that it failed to be GPI-anchored to the cell membrane.
  • [MeSH-major] Astrocytoma / metabolism. Brain Neoplasms / metabolism. Cell Nucleus / metabolism. Prions / biosynthesis. RNA, Messenger / metabolism
  • [MeSH-minor] Blotting, Northern. Blotting, Western. Cell Line, Tumor. Cytoplasm / metabolism. GPI-Linked Proteins. Gene Expression. Gene Expression Profiling. Humans. Immunohistochemistry. Protein Biosynthesis. Reverse Transcriptase Polymerase Chain Reaction. Transcription, Genetic. Transfection

  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • COS Scholar Universe. author profiles.
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17089057.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / GPI-Linked Proteins; 0 / PRND protein, human; 0 / Prions; 0 / RNA, Messenger
  •  go-up   go-down


98. Utsuki S, Oka H, Sato K, Shimizu S, Suzuki S, Fujii K: Fluorescence diagnosis of tumor cells in hemangioblastoma cysts with 5-aminolevulinic acid. J Neurosurg; 2010 Jan;112(1):130-2
Genetic Alliance. consumer health - Hemangioblastoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fluorescence diagnosis of tumor cells in hemangioblastoma cysts with 5-aminolevulinic acid.
  • Peritumoral hemangioblastoma cysts are usually composed of fibrous tissue without tumor cells.
  • The authors describe the first case in which fluorescence with 5-aminolevulinic acid (5-ALA) was used to diagnose a hemangioblastoma tumor in a peritumoral cyst wall.
  • A 27-year-old woman with a homogeneous, enhanced nodular lesion in the right hemisphere of the cerebellum underwent surgical treatment.
  • The fluorescent cyst consisted of tumor cells.
  • [MeSH-major] Aminolevulinic Acid. Central Nervous System Cysts / diagnosis. Cerebellar Neoplasms / diagnosis. Hemangioblastoma / diagnosis. Photosensitizing Agents
  • [MeSH-minor] Adult. Female. Fluorescence. Humans. Magnetic Resonance Imaging. Neurosurgical Procedures / methods. Photomicrography. Spectrometry, Fluorescence

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] J Neurosurg. 2011 Mar;114(3):886; author reply 886-7 [21275559.001]
  • (PMID = 19480541.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Photosensitizing Agents; 88755TAZ87 / Aminolevulinic Acid
  •  go-up   go-down


99. Morawski KF, Niemczyk K, Bohorquez J, Marchel A, Delgado RE, Ozdamar O, Telischi FF: Intraoperative monitoring of hearing during cerebellopontine angle tumor surgery using transtympanic electrocochleography. Otol Neurotol; 2007 Jun;28(4):541-5
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intraoperative monitoring of hearing during cerebellopontine angle tumor surgery using transtympanic electrocochleography.
  • PATIENTS: Fifteen patients with cerebellopontine angle tumor among 50 patients were included in this study.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Acta Neurochir (Wien). 2000;142(9):1037-45 [11086814.001]
  • [Cites] Acta Neurochir (Wien). 2001 Oct;143(10):985-95; discussion 995-6 [11685605.001]
  • [Cites] Otol Neurotol. 2004 Sep;25(5):818-25 [15354017.001]
  • [Cites] Eur Arch Otorhinolaryngol. 1992;249(5):257-62 [1524806.001]
  • [Cites] J Neural Eng. 2005 Jun;2(2):1-10 [15928407.001]
  • [Cites] Am J Otol. 1996 May;17(3):452-60 [8817025.001]
  • [Cites] Am J Otol. 1998 Jul;19(4):503-12 [9661763.001]
  • [Cites] J Neurol Neurosurg Psychiatry. 1999 May;66(5):591-9 [10209169.001]
  • [Cites] Am J Otol. 1993 Jan;14(1):63-9 [8424478.001]
  • (PMID = 17529854.001).
  • [ISSN] 1531-7129
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] ENG
  • [Grant] United States / NIDCD NIH HHS / DC / DC004344-02; United States / NIDCD NIH HHS / DC / R44 DC004344; United States / NIDCD NIH HHS / DC / 2R44DC04344-02; United States / NIDCD NIH HHS / DC / R44 DC004344-02
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS27764; NLM/ PMC2094124
  •  go-up   go-down


100. Alobid I, Gastón F, Morello A, Guilemany JM, Mullol J: Peripheral primitive neuroectodermal tumor of the cerebellopontine angle. Acta Otolaryngol; 2005 Apr;125(4):426-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Peripheral primitive neuroectodermal tumor of the cerebellopontine angle.
  • Peripheral primitive neuroectodermal tumors are highly malignant small cell neoplasms.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Cerebellopontine Angle / pathology. Neuroectodermal Tumors, Primitive, Peripheral / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Ear, Inner / pathology. Ear, Inner / surgery. Female. Follow-Up Studies. Head and Neck Neoplasms / pathology. Head and Neck Neoplasms / therapy. Humans. Magnetic Resonance Imaging. Neoplasm Invasiveness. Neoplasms, Second Primary / pathology. Neoplasms, Second Primary / therapy. Retreatment

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15823816.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Norway
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down






Advertisement