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6. Warren K, Jakacki R, Widemann B, Aikin A, Libucha M, Packer R, Vezina G, Reaman G, Shaw D, Krailo M, Osborne C, Cehelsky J, Caldwell D, Stanwood J, Steinberg SM, Balis FM: Phase II trial of intravenous lobradimil and carboplatin in childhood brain tumors: a report from the Children's Oncology Group. Cancer Chemother Pharmacol; 2006 Sep;58(3):343-7
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  • [Title] Phase II trial of intravenous lobradimil and carboplatin in childhood brain tumors: a report from the Children's Oncology Group.
  • BACKGROUND: [corrected] Lobradimil is a synthetic bradykinin analog that rapidly and transiently increases the permeability of the blood-brain barrier (BBB).
  • The combination of lobradimil and carboplatin was studied in pediatric patients with primary brain tumors in a phase II trial, the primary endpoints of which were to estimate the response rate and time to disease progression.
  • PATIENTS AND METHODS: Patients were stratified by histology into five cohorts: brainstem glioma, high-grade glioma, low-grade glioma, medullobastoma/primitive neuroectodermal tumor (PNET), and ependymoma.
  • No objective responses were observed in the brainstem glioma (n=12) and high-grade glioma (n = 9) cohorts, although two patients with high-grade glioma had prolonged disease stabilization (>6 months).
  • CONCLUSION: The combination of lobradimil and carboplatin was inactive in childhood high-grade gliomas and brainstem gliomas.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Blood-Brain Barrier / metabolism. Brain Neoplasms / drug therapy
  • [MeSH-minor] Adolescent. Adult. Bradykinin / administration & dosage. Bradykinin / adverse effects. Bradykinin / analogs & derivatives. Bradykinin / therapeutic use. Carboplatin / administration & dosage. Carboplatin / adverse effects. Carboplatin / therapeutic use. Child. Child, Preschool. Cohort Studies. Drug Administration Schedule. Humans. Infusions, Intravenous. Treatment Outcome

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  • (PMID = 16408203.001).
  • [ISSN] 0344-5704
  • [Journal-full-title] Cancer chemotherapy and pharmacology
  • [ISO-abbreviation] Cancer Chemother. Pharmacol.
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / /
  • [Publication-type] Clinical Trial, Phase II; Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 159768-75-9 / RMP 7; BG3F62OND5 / Carboplatin; S8TIM42R2W / Bradykinin
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7. Terasaki M, Bouffet E, Katsuki H, Fukushima S, Shigemori M: Pilot trial of the rate of response, safety, and tolerability of temozolomide and oral VP-16 in patients with recurrent or treatment-induced malignant central nervous system tumors. Surg Neurol; 2008 Jan;69(1):46-50
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  • BACKGROUND: The aim of this study was to determine the response and toxicity of patients with recurrent or treatment-induced brain tumors to TMZ and oral VP-16.
  • METHODS: Eleven patients with recurrent or treatment-induced malignant CNS tumors, including treatment-induced PNET (in 1 patient), brainstem glioma (in 3 patients; 1 with treatment-induced, 2 with recurrence), recurrent anaplastic astrocytoma (in 3 patients), and recurrent glioblastoma (in 4 patients) were evaluated in a pilot study of TMZ and oral VP-16 chemotherapy.
  • The histologic subtype of the tumor, its location, and its maximum response to chemotherapy did not have an impact on the duration of disease control.
  • CONCLUSION: This limited pilot study confirms the innocuousness and the activity of the combination of TMZ and oral VP-16 in recurrent malignant brain tumors.
  • [MeSH-major] Antineoplastic Agents / administration & dosage. Brain Neoplasms / drug therapy. Dacarbazine / analogs & derivatives. Etoposide / administration & dosage. Neoplasm Recurrence, Local / drug therapy. Neoplasms, Neuroepithelial / drug therapy. Neoplasms, Second Primary / drug therapy
  • [MeSH-minor] Administration, Oral. Adolescent. Adult. Aged. Drug Therapy, Combination. Female. Humans. Male. Middle Aged. Pilot Projects. Treatment Outcome

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  • (PMID = 18054615.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 6PLQ3CP4P3 / Etoposide; 7GR28W0FJI / Dacarbazine; 85622-93-1 / temozolomide
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8. Uchino M, Haga D, Nomoto J, Mito T, Kuramitsu T: Brainstem involvement in hypertensive encephalopathy: a report of two cases and literature review. Eur Neurol; 2007;57(4):223-6
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  • [Title] Brainstem involvement in hypertensive encephalopathy: a report of two cases and literature review.
  • The cerebral hemispheres show prominent involvement in hypertensive encephalopathy far more frequently than the brainstem.
  • Two patients with severe paroxysmally accelerated hypertension associated with brainstem hyperintensity in T2-weighted magnetic resonance images are presented.
  • Extreme acceleration of hypertension may be essential for breakdown of autoregulation in the brainstem circulation.
  • The marked clinicoradiologic dissociation ruled out major brainstem infarction and made tumor unlikely.
  • [MeSH-major] Brain Stem / pathology. Hypertensive Encephalopathy / diagnosis. Magnetic Resonance Imaging
  • [MeSH-minor] Adult. Blood Pressure / drug effects. Cerebral Hemorrhage / radiography. Confusion / etiology. Confusion / psychology. Headache / etiology. Humans. Injections, Intravenous. Male. Nitroprusside / administration & dosage. Nitroprusside / therapeutic use. Tomography, X-Ray Computed. Vasodilator Agents / administration & dosage. Vasodilator Agents / therapeutic use. Verapamil / therapeutic use

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  • [Copyright] 2007 S. Karger AG, Basel
  • (PMID = 17312370.001).
  • [ISSN] 1421-9913
  • [Journal-full-title] European neurology
  • [ISO-abbreviation] Eur. Neurol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Vasodilator Agents; 169D1260KM / Nitroprusside; CJ0O37KU29 / Verapamil
  • [Number-of-references] 25
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9. Matsumoto H, Ugawa Y: [Paraneoplastic opsoclonus-myoclonus syndrome--a review]. Brain Nerve; 2010 Apr;62(4):365-9
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  • Parainfectious brainstem encephalitis, toxic-metabolic disturbances and others condition should be considered as potential causes of these symptoms.
  • In adults, POMS is less responsive to immunotherapy and improves only with tumor resection.
  • [MeSH-minor] Adrenocorticotropic Hormone / therapeutic use. Adult. Antibodies, Monoclonal / therapeutic use. Antibodies, Monoclonal, Murine-Derived. Child. Cyclophosphamide / therapeutic use. Humans. Immunity, Cellular. Immunity, Humoral. Immunoglobulins, Intravenous / therapeutic use. Immunotherapy. Plasma Exchange. Prognosis. Rituximab

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  • (PMID = 20420176.001).
  • [ISSN] 1881-6096
  • [Journal-full-title] Brain and nerve = Shinkei kenkyū no shinpo
  • [ISO-abbreviation] Brain Nerve
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Autoantibodies; 0 / Immunoglobulins, Intravenous; 4F4X42SYQ6 / Rituximab; 8N3DW7272P / Cyclophosphamide; 9002-60-2 / Adrenocorticotropic Hormone
  • [Number-of-references] 22
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10. Benesch M, Lackner H, Sovinz P, Suppan E, Schwinger W, Eder HG, Dornbusch HJ, Moser A, Triebl-Roth K, Urban C: Late sequela after treatment of childhood low-grade gliomas: a retrospective analysis of 69 long-term survivors treated between 1983 and 2003. J Neurooncol; 2006 Jun;78(2):199-205
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  • Eighty-seven patients with low-grade gliomas grouped according to tumor location (cerebellum: n=28; cerebral hemispheres: n=21; central midline: n=15; brainstem: n=12; tectum: n=5; other locations: n=6) were evaluated for tumor- and/or treatment-related late effects by analysis of medical and computer records, and personal interviews.
  • Median follow-up of survivors is 96 months with an overall survival of 79% (cerebellum: 89%; cerebral hemispheres: 95%; central midline: 80%; brainstem: 25%; tectum: 100%; other locations: 66%).
  • Chronic medical problems (mild ataxia to multiple severe neuroendocrine deficits) are observed in 100% of patients with brainstem/central midline tumors and in 40-50% of patients with low-grade gliomas of other locations.
  • Tumor- and treatment-related late effects are common in patients with low-grade gliomas with the most severe occurring in patients with brainstem or central midline tumors.
  • As long-term survival is excellent in patients with low-grade gliomas except for tumors located in the brainstem, future treatment studies should focus on avoiding long-term late effects.
  • [MeSH-major] Brain Neoplasms / therapy. Endocrine System Diseases / epidemiology. Glioma / therapy. Nervous System Diseases / epidemiology
  • [MeSH-minor] Adolescent. Adult. Antineoplastic Agents / adverse effects. Austria / epidemiology. Child. Child, Preschool. Cohort Studies. Combined Modality Therapy / adverse effects. Disease-Free Survival. Female. Follow-Up Studies. Hearing Disorders / epidemiology. Hearing Disorders / etiology. Humans. Infant. Male. Radiation Injuries / epidemiology. Retrospective Studies. Survivors / statistics & numerical data. Vision Disorders / epidemiology. Vision Disorders / etiology


11. Nakaya K, Niranjan A, Kondziolka D, Kano H, Khan AA, Nettel B, Koebbe C, Pirris S, Flickinger JC, Lunsford LD: Gamma knife radiosurgery for benign tumors with symptoms from brainstem compression. Int J Radiat Oncol Biol Phys; 2010 Jul 15;77(4):988-95
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  • [Title] Gamma knife radiosurgery for benign tumors with symptoms from brainstem compression.
  • PURPOSE: This study evaluated the role of radiosurgery in the management of symptomatic patients with brainstem compression from benign basal tumors.
  • METHODS AND MATERIALS: Over a 17-year, period 246 patients (202 vestibular schwannomas and 44 meningiomas) with brainstem compression from benign skull-base tumors were managed with Gamma Knife radiosurgery.
  • Median tumor volumes were 3.9 cm(3) (range, 0.8-39.0 mL) and 6.6 mL (range, 1.6-25.1 mL) for vestibular schwannomas and meningiomas, respectively.
  • Patients were categorized into four groups on the basis of the tumor-brainstem relationship on neuroimaging.
  • RESULTS: Preservation of function was stratified according to grade of brainstem compression.
  • We analyzed the effect of radiosurgery on symptoms of brainstem compression.
  • The tumor control rate was 100 % for meningioma and 97% for vestibular schwannomas (although 5% required an additional procedure such as a ventriculoperitoneal shunt).
  • Balance improved significantly in patients who had less tumor compression (p = 0.0357) after radiosurgery.
  • CONCLUSION: Radiosurgery is a minimally invasive option for patients with benign basal tumors that indent or distort the brainstem.
  • A high tumor growth control rate and satisfactory rate of neurological preservation and symptom control can be obtained with radiosurgery.
  • [MeSH-major] Brain Stem. Meningeal Neoplasms / surgery. Meningioma / surgery. Neuroma, Acoustic / surgery. Radiosurgery / methods. Skull Base Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Analysis of Variance. Constriction, Pathologic / surgery. Female. Humans. Male. Middle Aged. Statistics, Nonparametric. Young Adult

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20381265.001).
  • [ISSN] 1879-355X
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
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12. Hayashi M, Chernov M, Tamura N, Yomo S, Ochiai T, Nagai M, Tamura M, Izawa M, Muragaki Y, Iseki H, Okada Y, Takakura K: Gamma Knife surgery for abducent nerve schwannoma. Report of 4 cases. J Neurosurg; 2010 Dec;113 Suppl:136-43
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  • All 4 tumors were located in the cavernous sinus: 2 of these tumors within the borders of the sinus, 1 tumor extending into the orbit, and 1 tumor extending into the prepontine cistern.
  • No patient underwent tumor resection.
  • The dose directed to the tumor margin was 12 Gy in all cases.
  • The dose directed to the anterior visual pathways was kept below 10 Gy and that to the brainstem below 14 Gy.
  • [MeSH-minor] Adult. Female. Humans. Male. Middle Aged. Radiotherapy Dosage. Treatment Outcome

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  • (PMID = 21121795.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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13. Carlson ML, Babovic-Vuksanovic D, Messiaen L, Scheithauer BW, Neff BA, Link MJ: Radiation-induced rhabdomyosarcoma of the brainstem in a patient with neurofibromatosis type 2. J Neurosurg; 2010 Jan;112(1):81-7
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  • [Title] Radiation-induced rhabdomyosarcoma of the brainstem in a patient with neurofibromatosis type 2.
  • The gene responsible for the development of NF2 acts as a tumor suppressor gene.
  • Compared with patients with sporadic tumors, NF2 patients having a germline tumor suppressor gene defect may be more prone to secondary malignancies after treatment involving radiation therapy.
  • [MeSH-major] Brain Stem Neoplasms / etiology. Neoplasms, Radiation-Induced / etiology. Neoplasms, Second Primary / etiology. Neurofibromatosis 2 / surgery. Radiosurgery / adverse effects. Rhabdomyosarcoma / etiology
  • [MeSH-minor] Adult. Brain Neoplasms / etiology. Brain Neoplasms / surgery. Brain Stem / pathology. Brain Stem / radiation effects. Brain Stem / surgery. Ear Neoplasms / etiology. Ear Neoplasms / surgery. Fatal Outcome. Female. Humans. Neurilemmoma / etiology. Neurilemmoma / surgery. Vestibular Diseases / etiology. Vestibular Diseases / surgery

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  • [ErratumIn] J Neurosurg. 2010 Jan;112(1):209. Scheithauer, Bernd B [corrected to Scheithauer, Bernd W]
  • (PMID = 19575577.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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4. Lo SS, Abdulrahman R, Desrosiers PM, Fakiris AJ, Witt TC, Worth RM, Dittmer PH, Desrosiers CM, Frost S, Timmerman RD: The role of Gamma Knife Radiosurgery in the management of unresectable gross disease or gross residual disease after surgery in ependymoma. J Neurooncol; 2006 Aug;79(1):51-6
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  • Two patients who received SRS to their brainstem lesions developed symptoms related to radionecrosis and were successfully treated with steroid with good control of symptoms.
  • SRS provides reasonable local control but out-of-field tumor progression remains an issue.
  • [MeSH-major] Brain Neoplasms / surgery. Ependymoma / surgery. Radiosurgery
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Female. Humans. Infant. Male. Neoplasm Recurrence, Local / surgery. Neoplasm, Residual. Survival Analysis. Survival Rate. Treatment Outcome

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  • [Cites] Neurosurgery. 1996 Apr;38(4):696-701; discussion 701-2 [8692387.001]
  • [Cites] Radiother Oncol. 1997 Jun;43(3):269-73 [9215786.001]
  • [Cites] Cancer. 2000 Feb 15;88(4):870-5 [10679657.001]
  • [Cites] J Neurooncol. 2004 Jan;66(1-2):187-90 [15015785.001]
  • [Cites] Pediatr Neurosurg. 1990-1991;16(2):57-65 [2132926.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1992;23 (2):313-9 [1587752.001]
  • [Cites] Stereotact Funct Neurosurg. 1995;64 Suppl 1:32-41 [8584838.001]
  • [Cites] Clin Neurosurg. 1997;44:559-70 [10080027.001]
  • [Cites] J Clin Oncol. 2004 Aug 1;22(15):3156-62 [15284268.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2001 Jul 15;50(4):929-35 [11429220.001]
  • [Cites] Stereotact Funct Neurosurg. 1999;73(1-4):23-30 [10853093.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1990 Dec;19(6):1497-502 [2262372.001]
  • [Cites] Pediatrics. 1990 May;85(5):774-82 [2184409.001]
  • [Cites] Oncology (Williston Park). 2002 May;16(5):629-42, 644; discussion 645-6, 648 [12108890.001]
  • [Cites] Med Pediatr Oncol. 1997 Aug;29(2):79-85 [9180907.001]
  • [Cites] J Pediatr Hematol Oncol. 1999 May-Jun;21(3):203-11 [10363853.001]
  • [Cites] J Neurosurg. 1997 Jun;86(6):943-9 [9171172.001]
  • [Cites] J Neurosurg. 1998 Apr;88(4):695-703 [9525716.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1994 Jan 15;28(2):381-6 [8276653.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1982 Jan;8(1):37-43 [7061255.001]
  • [Cites] Neurosurgery. 1991 May;28(5):666-71; discussion 671-2 [1876244.001]
  • [Cites] Pediatr Neurosurg. 1996;24(3):119-25 [8870014.001]
  • [Cites] Neurosurgery. 1995 Oct;37(4):655-66; discussion 666-7 [8559293.001]
  • [Cites] Cancer. 1997 Jul 15;80(2):341-7 [9217048.001]
  • [Cites] J Neurosurg. 1990 Mar;72(3):408-17 [2303876.001]
  • (PMID = 16557349.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


15. Lisowska G, Namysłowski G, Misiołek M, Scierski W, Orecka B, Czecior E, Dziendziel A: [Efferent suppression test--sensitivity and specificity]. Otolaryngol Pol; 2008;62(6):747-54
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  • MATERIAL AND METHODS: To evaluate the function of MOC system click evoked otoacoustic emissions (CEOAEs) with and without continuous contralateral broadband noise (BBN) stimulation were recorded in 14 patients with multiple sclerosis, 16 patients with unilateral cerebello-pontine angle tumor and control group matched for age and gender.
  • The MOC suppression test may provide a tool for an early diagnosis of the brainstem pathology.
  • [MeSH-minor] Acoustic Stimulation / instrumentation. Adult. Audiometry, Pure-Tone. Auditory Threshold. Case-Control Studies. Female. Humans. Male. Middle Aged. Poland. Sensitivity and Specificity. Severity of Illness Index

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  • (PMID = 19205524.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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16. Joshi BH, Puri RA, Leland P, Varricchio F, Gupta G, Kocak M, Gilbertson RJ, Puri RK, US Pediatric Brain Tumor Consortium: Identification of interleukin-13 receptor alpha2 chain overexpression in situ in high-grade diffusely infiltrative pediatric brainstem glioma. Neuro Oncol; 2008 Jun;10(3):265-74
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  • [Title] Identification of interleukin-13 receptor alpha2 chain overexpression in situ in high-grade diffusely infiltrative pediatric brainstem glioma.
  • Human malignant glioma cell lines and adult brain tumors overexpress high levels of interleukin-13 receptor alpha2 chain (IL-13Ralpha2).
  • Because the IL-13Ralpha2 chain is an important target for cancer therapy and prognosis for patients with brainstem glioma (BSG) remains dismal, we investigated the expression of this receptor in specimens of diffusely infiltrative pediatric BSG relative to normal brain tissue.
  • Twenty-eight BSG specimens and 15 normal brain specimens were investigated for IL-13Ralpha2 protein expression by immunohistochemical analysis (IHC) using two different antibodies in two different laboratories.
  • By Q-dot IHC or a standard IHC assay, 17 of 28 (61%) tumor specimens showed modest to strong staining for IL-13Ralpha2, while 15 normal brain tissue samples showed weak expression for IL-13Ralpha2 protein.
  • High-level IL-13Ralpha2 RNA expression was detected in tumor samples by Q-dot ISH, but only weak RNA expression was observed in normal brain.
  • IL-13Ralpha2 protein and mRNA are expressed to significantly higher levels in BSG than in normal brain tissue.

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  • [Cites] Hum Gene Ther. 2000 Sep 1;11(13):1829-35 [10986556.001]
  • [Cites] Blood. 2000 Jun 1;95(11):3506-13 [10828036.001]
  • [Cites] Cancer Res. 2001 Aug 15;61(16):6194-200 [11507072.001]
  • [Cites] Cancer Gene Ther. 2001 Nov;8(11):861-8 [11773976.001]
  • [Cites] Cancer Res. 2002 Feb 15;62(4):1103-9 [11861389.001]
  • [Cites] Oncol Res. 2001;12(11-12):459-67 [11939409.001]
  • [Cites] Curr Treat Options Oncol. 2001 Dec;2(6):529-36 [12057098.001]
  • [Cites] J Clin Oncol. 2002 Aug 15;20(16):3431-7 [12177103.001]
  • [Cites] J Immunol. 2002 Dec 15;169(12):7119-26 [12471149.001]
  • [Cites] J Exp Med. 2003 Mar 17;197(6):703-9 [12642602.001]
  • [Cites] Clin Cancer Res. 2003 Sep 1;9(10 Pt 1):3620-4 [14506149.001]
  • [Cites] J Neurooncol. 2003 Oct;65(1):37-48 [14649884.001]
  • [Cites] Cancer. 2004 Sep 1;101(5):1036-42 [15329913.001]
  • [Cites] Mol Cell Biol. 1991 Apr;11(4):2200-5 [2005905.001]
  • [Cites] J Neurosurg. 1993 Oct;79(4):569-76 [7692018.001]
  • [Cites] Int J Cancer. 1994 Aug 15;58(4):574-81 [8056454.001]
  • [Cites] J Biol Chem. 1995 Apr 14;270(15):8797-804 [7721786.001]
  • [Cites] J Biol Chem. 1995 Jul 14;270(28):16775-80 [7622490.001]
  • [Cites] J Immunol. 1996 Apr 15;156(8):2972-8 [8609418.001]
  • [Cites] J Biol Chem. 1996 Sep 13;271(37):22428-33 [8798406.001]
  • [Cites] Pediatr Neurosurg. 1996;24(4):185-92 [8873160.001]
  • [Cites] Cancer Res. 1996 Dec 15;56(24):5631-7 [8971168.001]
  • [Cites] J Immunol. 1997 Jan 15;158(2):756-64 [8992992.001]
  • [Cites] Mol Med. 1997 May;3(5):327-38 [9205948.001]
  • [Cites] Cancer Res. 1997 Aug 1;57(15):3272-80 [9242460.001]
  • [Cites] J Biol Chem. 1997 Aug 8;272(32):20251-8 [9242704.001]
  • [Cites] J Urol. 1997 Sep;158(3 Pt 1):948-53 [9258124.001]
  • [Cites] Biochem Biophys Res Commun. 1997 Sep 8;238(1):90-4 [9299458.001]
  • [Cites] Nat Med. 1997 Dec;3(12):1362-8 [9396606.001]
  • [Cites] Int Immunol. 1998 Aug;10(8):1103-10 [9723696.001]
  • [Cites] J Natl Cancer Inst. 1998 Sep 2;90(17):1269-77 [9731733.001]
  • [Cites] Clin Cancer Res. 1995 Nov;1(11):1253-8 [9815919.001]
  • [Cites] Clin Cancer Res. 1997 Feb;3(2):151-6 [9815666.001]
  • [Cites] Int J Mol Med. 1998 Mar;1(3):551-7 [9852261.001]
  • [Cites] Biophys J. 1999 Jul;77(1):154-72 [10388747.001]
  • [Cites] Cancer Res. 2005 Apr 1;65(7):2956-63 [15805299.001]
  • [Cites] Nat Med. 2006 Jan;12(1):99-106 [16327802.001]
  • [Cites] Technol Cancer Res Treat. 2006 Jun;5(3):239-50 [16700620.001]
  • [Cites] Clin Cancer Res. 2006 May 15;12(10):3145-51 [16707614.001]
  • [Cites] Vitam Horm. 2006;74:479-504 [17027527.001]
  • [Cites] J Clin Oncol. 2007 Mar 1;25(7):837-44 [17327604.001]
  • [Cites] Int J Hematol. 1999 Jan;69(1):13-20 [10641437.001]
  • [Cites] Cancer Res. 2000 Mar 1;60(5):1168-72 [10728667.001]
  • [Cites] Int J Cancer. 2001 Apr 15;92(2):168-75 [11291041.001]
  • (PMID = 18430795.001).
  • [ISSN] 1522-8517
  • [Journal-full-title] Neuro-oncology
  • [ISO-abbreviation] Neuro-oncology
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / U01 CA081457; United States / NCI NIH HHS / CA / U01 CA81457
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Interleukin-13 Receptor alpha2 Subunit; 0 / RNA, Messenger
  • [Other-IDs] NLM/ PMC2563049
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17. Menon G, Krishnakumar K, Nair S: Adult medulloblastoma: clinical profile and treatment results of 18 patients. J Clin Neurosci; 2008 Feb;15(2):122-6
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  • [Title] Adult medulloblastoma: clinical profile and treatment results of 18 patients.
  • The objective of this article is to examine the clinicoradiological features and surgical outcomes of adult patients (>16 years) with medulloblastoma.
  • The following variables were assessed by bivariate analyses: age, location of the lesion, brainstem invasion, extent of excision and histological subtype.
  • The tumor was located in the vermis in 12 patients (66.6%) and in the cerebellar hemisphere in six (16.6%).
  • MRI evidence of brainstem infiltration was seen in three patients (16.6%).
  • Desmoplastic variant histology was not observed to be a significant prognostic factor in the adult group while brain stem invasion carried a poor prognosis.
  • [MeSH-minor] Adolescent. Adult. Age Factors. Female. Humans. Male. Middle Aged. Prognosis. Retrospective Studies. Statistics, Nonparametric. Treatment Outcome

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  • (PMID = 18078755.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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18. Colletti V: Auditory outcomes in tumor vs. nontumor patients fitted with auditory brainstem implants. Adv Otorhinolaryngol; 2006;64:167-85
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  • [Title] Auditory outcomes in tumor vs. nontumor patients fitted with auditory brainstem implants.
  • Auditory brainstem implants (ABIs) are currently indicated for patients older than 12 years with neurofibromatosis type 2 (NF2) who had bilateral schwannoma removed.
  • Over the last 10 years, we have extended the indications for ABIs to nontumor children and adult patients with cochlear or cochlear nerve injuries or malfunctions who would not benefit from a cochlear implant.
  • In the present chapter we report our recent findings in adult ABI patients and compare the psychophysical and speech perception outcomes in tumor with those in nontumor patients.
  • We demonstrate that the ABI can stimulate the central auditory system in a way that gives the ability of open set speech understanding, and can thus be indicated in nontumor adult patients who are not candidates for a cochlear implant.
  • At 1 year after implantations nontumor adults scored from 12 to 100% in open set speech perception tests (average 59%), and tumor (NF2) patients scored from 5 to 30% (average of 11%).
  • To investigate the cause of the differences in performance between tumor and nontumor ABI recipients, a series of psychophysical tests were done consecutively in 39 adult patients with implants (25 nontumor and 14 tumor patients) from May 1999 to April 2004 and with a follow-up of at least 1 year.
  • (1) The ABIs allow most tumor and nontumor patients to experience improved communication as well as awareness of environmental sounds. (2) Nontumor patients had better hearing outcomes than tumor patients when the variation in the auditory benefit with the ABI in relation to the patient's underlying pathological conditions were taken into consideration. (3) A significant number of nontumor patients are able understand speech at a level comparable to that of the most successful cochlear implant users including conversational telephone use. (4) The ABI represents the tool for hearing rehabilitation in patients with profound hearing loss who cannot be fitted with cochlear implants.
  • [MeSH-major] Auditory Brain Stem Implants. Ear Neoplasms / surgery. Hearing Loss / surgery. Neurilemmoma / surgery. Neurofibromatosis 2 / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Case-Control Studies. Child. Child, Preschool. Female. Follow-Up Studies. Humans. Infant. Male. Middle Aged. Postoperative Care. Speech Perception / physiology. Treatment Outcome

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  • (PMID = 16891842.001).
  • [ISSN] 0065-3071
  • [Journal-full-title] Advances in oto-rhino-laryngology
  • [ISO-abbreviation] Adv. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 38
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19. Dong Y, Wei SH, Pi YL, Yan RM: [Ocular manifestations of brainstem tumor]. Zhonghua Yan Ke Za Zhi; 2009 Nov;45(11):999-1003
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  • [Title] [Ocular manifestations of brainstem tumor].
  • OBJECTIVE: To investigate the ocular manifestations of brainstem tumors and to avoid misdiagnosis and missed diagnosis.
  • The clinical data of 57 brainstem tumor in-patients were collected from 1993 to 2007.
  • RESULTS: The present series included 51 cases of brainstem germinoma, 4 cases of cavernous hemangioma, 1 case of hemangioblastoma and 1 case of metastatic tumor.
  • In 51 cases of brainstem germinoma, there were 37 males and 14 females.
  • The high incident ages of brainstem germinoma were 10 - 35 years.
  • CONCLUSIONS: Ocular manifestations occur frequently in brainstem tumor.
  • Nuclear ophthalmoplegia, nystagmus and other neuro-ophthalmic signs provide helpful clues for the diagnosis of brainstem tumor.
  • [MeSH-major] Brain Stem Neoplasms / pathology. Eye Diseases / pathology
  • [MeSH-minor] Adolescent. Adult. Brain Stem / pathology. Child. Child, Preschool. Female. Humans. Male. Middle Aged. Retrospective Studies. Young Adult

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  • (PMID = 20137418.001).
  • [ISSN] 0412-4081
  • [Journal-full-title] [Zhonghua yan ke za zhi] Chinese journal of ophthalmology
  • [ISO-abbreviation] Zhonghua Yan Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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20. Luetjens G, Mirzayan MJ, Brandis A, Krauss JK: Exophytic giant cell glioblastoma of the medulla oblongata. J Neurosurg; 2009 Mar;110(3):589-93
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  • A giant cell glioblastoma may be associated with a better prognosis than the common type of GBM after combined treatment involving tumor resection and radiochemotherapy.
  • A giant cell glioblastoma may occur at various sites in the brain and spinal cord.
  • To the authors' knowledge, this type of tumor has not been previously reported as arising as an exophytic tumor from the medulla oblongata.
  • The authors report on a 40-year-old man who presented with a large tumor located in the caudal fourth ventricle.
  • The tumor was removed completely and the patient underwent percutaneous radiotherapy with 60 Gy and concomitant chemotherapy with temozolomide.
  • Histopathological examination of the tumor revealed the typical features of a giant cell glioblastoma.
  • At the 2-year follow-up the patient was doing well and showed no signs of tumor recurrence.
  • It is important to identify variants of GBM because they may predict favorable long-term outcome, even when they arise from the caudal brainstem.
  • [MeSH-major] Brain Neoplasms / pathology. Glioblastoma / pathology. Medulla Oblongata
  • [MeSH-minor] Adult. Combined Modality Therapy. Humans. Male

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  • (PMID = 19061354.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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21. Kesari S, Kim RS, Markos V, Drappatz J, Wen PY, Pruitt AA: Prognostic factors in adult brainstem gliomas: a multicenter, retrospective analysis of 101 cases. J Neurooncol; 2008 Jun;88(2):175-83
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  • [Title] Prognostic factors in adult brainstem gliomas: a multicenter, retrospective analysis of 101 cases.
  • BACKGROUND: Adult brainstem gliomas (BSG) are uncommon and poorly understood with respect to prognostic factors.
  • Out of 24 candidate prognosis factors, we selected seven covariates for proportional hazards model by Lasso procedure: age of diagnosis, ethnicity, need for corticosteroids, tumor grade, dysphagia, tumor location, and karnofsky performance status (KPS).
  • Multivariate analysis showed that four covariates significantly increased hazard for survival: ethnicity, tumor location, age of diagnosis, and tumor grade.
  • [MeSH-major] Brain Stem Neoplasms / diagnosis. Glioma / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Algorithms. Disease Progression. Female. Follow-Up Studies. Health Surveys. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Multivariate Analysis. Prognosis. Retrospective Studies. Survival Analysis

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  • [Cites] Neurol Med Chir (Tokyo). 1993 Sep;33(9):625-9 [7505402.001]
  • [Cites] AJNR Am J Neuroradiol. 1985 Mar-Apr;6(2):159-63 [3920875.001]
  • [Cites] J Clin Neurosci. 2006 May;13(4):431-7 [16678721.001]
  • [Cites] Neurosurgery. 1993 Dec;33(6):1026-9; discussion 1029-30 [8133987.001]
  • [Cites] Indian J Cancer. 1999 Jun-Dec;36(2-4):99-108 [10921213.001]
  • [Cites] Brain. 2001 Dec;124(Pt 12):2528-39 [11701605.001]
  • [Cites] Pediatr Neurosurg. 1996 Jul;25(1):45-53 [9055335.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1993 Jan 15;25(2):235-41 [8420871.001]
  • [Cites] Ethn Dis. 2004 Summer;14(3):360-71 [15328937.001]
  • [Cites] J Clin Oncol. 2006 Mar 10;24(8):1266-72 [16525181.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1992;24(4):599-610 [1429081.001]
  • [Cites] J Neurosurg. 1989 Dec;71(6):826-36 [2585073.001]
  • [Cites] Cancer. 1980 Jun 1;45(11):2787-92 [7379009.001]
  • [Cites] J Neurosurg. 1986 Dec;65(6):751-5 [3772472.001]
  • [Cites] Acta Neurochir (Wien). 1999;141(7):721-6; discussion 726-7 [10481783.001]
  • [Cites] Pediatr Neurosurg. 2001 Apr;34(4):206-14 [11359114.001]
  • [Cites] Pediatr Neurosurg. 1996 Jul;25(1):41-4 [9055334.001]
  • [Cites] J Proteome Res. 2007 Feb;6(2):559-70 [17269713.001]
  • [Cites] J Neurosurg. 1984 Oct;61(4):665-73 [6470776.001]
  • [Cites] Neurology. 1986 May;36(5):602-5 [3703258.001]
  • [Cites] Pediatr Neurosurg. 1990-1991;16(2):73-83 [2132928.001]
  • [Cites] Neurology. 1998 Oct;51(4):1136-9 [9781543.001]
  • [Cites] Acta Neurochir (Wien). 1986;79(2-4):67-73 [3962745.001]
  • [Cites] Neurology. 1985 Mar;35(3):397-401 [3974898.001]
  • [Cites] Childs Nerv Syst. 2004 Mar;20(3):143-53 [14669023.001]
  • [Cites] Stat Med. 1997 Feb 28;16(4):385-95 [9044528.001]
  • [Cites] J Neurosurg. 1993 Jun;78(6):859-63 [8487066.001]
  • [Cites] Neurosurgery. 1983 Mar;12 (3):298-302 [6302553.001]
  • [Cites] Am J Dis Child. 1970 Jun;119(6):465-72 [4315314.001]
  • [Cites] Cancer. 1989 Jun 1;63(11):2124-9 [2720563.001]
  • [Cites] Cancer Treat Res. 1995;75:95-112 [7640169.001]
  • [Cites] Surg Neurol. 1995 Jun;43(6):563-7; discussion 567-8 [7482235.001]
  • [Cites] Cancer. 1982 Mar 15;49(6):1294-6 [6277461.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1991 Apr;20(4):757-60 [2004952.001]
  • [Cites] Pediatr Neurosurg. 1996;24(4):185-92 [8873160.001]
  • [Cites] Neurosurgery. 1980 Sep;7(3):243-8 [7207742.001]
  • (PMID = 18365144.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
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22. Yamamoto T, Tsuji S: [Anti-Ma2-associated encephalitis and paraneoplastic limbic encephalitis]. Brain Nerve; 2010 Aug;62(8):838-51
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  • Anti-Ma2-associated encephalitis (or anti-Ma2 encephalitis) is a paraneoplastic neurological syndrome (PNS) characterized by isolated or combined limbic, diencephalic, or brainstem dysfunction.
  • Of the remaining, many exhibit excessive daytime sleepiness, vertical ophthalmoparesis, or both associated with LE, because of frequent involvement of the diencephalon and/or upper brainstem.
  • These patients may have predominant cerebellar and/or brainstem dysfunctions due to more extensive involvement of subtentorial structures.
  • While it can cause severe neurological deficits or death in a substantial proportion of the patients, approximately one-third show neurological improvement and another 20 - 40% stabilize in response to treatment, including immunotherapy and/or tumor treatment.
  • We experienced a 40-year-old patient with severe hypokinesis caused by anti-Ma2 encephalitis associated with bilateral intratubular germ-cell neoplasm of the testes.
  • [MeSH-major] Antigens, Neoplasm / immunology. Autoantibodies. Limbic Encephalitis. Nerve Tissue Proteins / immunology
  • [MeSH-minor] Adult. Animals. Biomarkers / blood. Biomarkers / cerebrospinal fluid. Carcinoma, Non-Small-Cell Lung. Diagnosis, Differential. Female. Humans. Lung Neoplasms. Male. Middle Aged. Neoplasms, Germ Cell and Embryonal. Prognosis. Testicular Neoplasms

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  • (PMID = 20714032.001).
  • [ISSN] 1881-6096
  • [Journal-full-title] Brain and nerve = Shinkei kenkyū no shinpo
  • [ISO-abbreviation] Brain Nerve
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Autoantibodies; 0 / Biomarkers; 0 / Ma2 antigen; 0 / Nerve Tissue Proteins
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23. Ruivo J, Antunes JL: Maffucci syndrome associated with a pituitary adenoma and a probable brainstem tumor. J Neurosurg; 2009 Feb;110(2):363-8
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  • [Title] Maffucci syndrome associated with a pituitary adenoma and a probable brainstem tumor.
  • Malignancies are a common feature of Maffucci syndrome, with chondrosarcomas being the most common tumor type.
  • The authors present the first case of Maffucci syndrome associated with a pituitary adenoma and a probable brainstem glioma and review the literature concerning intracranial tumors related to this disease.
  • Neuroimaging revealed a pituitary macroadenoma and a suspected brainstem tumor.
  • [MeSH-major] Brain Stem Neoplasms / complications. Enchondromatosis / complications. Magnetic Resonance Imaging. Neoplasms, Multiple Primary / complications. Pituitary Neoplasms / complications. Pons
  • [MeSH-minor] Adult. Decompression, Surgical. Female. Humans. Nerve Compression Syndromes / diagnosis. Nerve Compression Syndromes / surgery. Optic Chiasm / pathology. Optic Nerve Diseases / diagnosis. Optic Nerve Diseases / surgery. Vision Disorders / diagnosis. Vision Disorders / etiology. Vision Disorders / surgery

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  • (PMID = 18976063.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 67
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24. Tanaka K, Sasayama T, Kawamura A, Kondoh T, Kanomata N, Kohmura E: Isolated oculomotor nerve paresis in anaplastic astrocytoma with exophytic invasion. Neurol Med Chir (Tokyo); 2006 Apr;46(4):198-201
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  • Computed tomography and magnetic resonance imaging showed an intra-axial tumor in the left temporal lobe, extending to the basal and prepontine cisterns, and compressing the brainstem.
  • The tumor was removed subtotally.
  • [MeSH-minor] Adult. Astrocytes / pathology. Biomarkers, Tumor / analysis. Brain Stem / pathology. Cerebral Arteries / pathology. Cisterna Magna / pathology. Dominance, Cerebral / physiology. Humans. Image Processing, Computer-Assisted. Magnetic Resonance Imaging. Male. Neoplasm Invasiveness / pathology. Nerve Compression Syndromes / diagnosis. Nerve Compression Syndromes / etiology. Nerve Compression Syndromes / pathology. Nerve Compression Syndromes / surgery. Neuronavigation. Oculomotor Nerve / pathology. Oculomotor Nerve / surgery. Pons / pathology

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  • (PMID = 16636512.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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25. Akiyama T, Ikeda E, Kawase T, Yoshida K: Pseudocapsule formation after gamma knife radiosurgery for trigeminal neurinoma--case report--. Neurol Med Chir (Tokyo); 2005 Oct;45(10):526-9
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  • Fifteen months after the GKR, follow-up MR imaging revealed tumor regrowth causing extensive compression of the brainstem, and cyst formation in the tumor.
  • The tumor was totally resected, but the left trigeminal nerve had to be sacrificed because of pseudocapsule formation which covered both the tumor and the trigeminal nerve fibers.
  • [MeSH-major] Cranial Nerve Neoplasms / surgery. Neoplasm Recurrence, Local / surgery. Neurilemmoma / surgery. Radiosurgery. Trigeminal Nerve Diseases / surgery
  • [MeSH-minor] Adult. Female. Humans. Reoperation

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  • (PMID = 16247239.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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26. Fayad JN, Keles B, Brackmann DE: Jugular foramen tumors: clinical characteristics and treatment outcomes. Otol Neurotol; 2010 Feb;31(2):299-305
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Presenting symptoms, otologic and neurotologic examination, audiologic thresholds, treatment procedure, surgical technique, tumor size and classification, and postoperative complications were recorded.
  • Extent of tumor removal was determined at time of surgery, followed by routine radiographic follow-up.
  • Total tumor removal was achieved in 81% of surgery cases.
  • However, subtotal removal may be required to preserve CN function, vital vascular structures, and the brainstem.
  • Postoperative radiotherapy is used to control residual tumor.
  • [MeSH-major] Glomus Jugulare Tumor / surgery. Meningioma / surgery. Neurilemmoma / surgery. Skull Base Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Audiometry, Pure-Tone. Cerebrovascular Circulation / physiology. Facial Nerve Diseases / etiology. Female. Humans. Laryngoscopy. Magnetic Resonance Angiography. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Recurrence, Local. Postoperative Complications / epidemiology. Retrospective Studies. Treatment Outcome

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  • (PMID = 19779386.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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27. Sandri A, Sardi N, Genitori L, Giordano F, Peretta P, Basso ME, Bertin D, Mastrodicasa L, Todisco L, Mussa F, Forni M, Ricardi U, Cordero di Montezemolo L, Madon E: Diffuse and focal brain stem tumors in childhood: prognostic factors and surgical outcome. Experience in a single institution. Childs Nerv Syst; 2006 Sep;22(9):1127-35
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diffuse and focal brain stem tumors in childhood: prognostic factors and surgical outcome. Experience in a single institution.
  • OBJECTIVE: Brainstem tumors (BSTs) are usually gliomas and are divided into diffuse BSTs (DBSTs) and focal BSTs (FBSTs).
  • Eight out of 17 patients had adjuvant chemo- and/or radiotherapy after progression: 6/8 are without neurological symptoms and 2/8 have died due to tumor progression.
  • [MeSH-major] Astrocytoma / surgery. Brain Stem Neoplasms / surgery. Ganglioglioma / surgery
  • [MeSH-minor] Adolescent. Adult. Brain Stem / pathology. Brain Stem / surgery. Chemotherapy, Adjuvant. Child. Child, Preschool. Combined Modality Therapy. Cranial Irradiation. Disease Progression. Disease-Free Survival. Female. Follow-Up Studies. Humans. Infant. Male. Prognosis. Radiation-Sensitizing Agents / administration & dosage. Radiotherapy, Adjuvant. Survival Rate. Vincristine / administration & dosage

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  • [Cites] Pediatr Neurosurg. 1994;20(1):2-10 [8142279.001]
  • [Cites] J Neurooncol. 1990 Dec;9(3):239-48 [1964962.001]
  • [Cites] Neurosurgery. 1993 Dec;33(6):1026-9; discussion 1029-30 [8133987.001]
  • [Cites] Acta Neurochir Suppl (Wien). 1991;53:148-58 [1803873.001]
  • [Cites] Med Pediatr Oncol. 1989;17(2):117-26 [2704333.001]
  • [Cites] J Neurosurg. 1987 Feb;66(2):227-33 [3806204.001]
  • [Cites] Neurosurgery. 1992 Aug;31(2):186-94 [1308661.001]
  • [Cites] J Neurosurg. 1986 Dec;65(6):751-5 [3772472.001]
  • [Cites] Med Pediatr Oncol. 1998 Dec;31(6):483-90 [9835900.001]
  • [Cites] Pediatr Neurosurg. 2001 Apr;34(4):206-14 [11359114.001]
  • [Cites] J Neurooncol. 1989 Nov;7(4):367-71 [2511279.001]
  • [Cites] J Neurooncol. 1996 May-Jun;28(2-3):207-22 [8832463.001]
  • [Cites] J Neurooncol. 1988 Dec;6(4):309-17 [3221258.001]
  • [Cites] Childs Nerv Syst. 2004 Mar;20(3):143-53 [14669023.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1999 Mar 15;43(5):959-64 [10192340.001]
  • [Cites] J Neurosurg. 1993 Jun;78(6):859-63 [8487066.001]
  • [Cites] Oncologist. 2004;9(2):197-206 [15047924.001]
  • [Cites] J Neurooncol. 1996 May-Jun;28(2-3):193-205 [8832462.001]
  • [Cites] Childs Nerv Syst. 1999 Oct;15(10):545-53 [10550585.001]
  • [Cites] Pediatr Neurosurg. 1990-1991;16(1):25-31; discussion 31 [2133406.001]
  • [Cites] Pediatr Neurosurg. 1996;24(1):9-23 [8817611.001]
  • [Cites] Pediatr Neurosurg. 1996;24(4):185-92 [8873160.001]
  • [Cites] Arch Dis Child. 1999 Jun;80(6):558-64 [10332008.001]
  • (PMID = 16568342.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Radiation-Sensitizing Agents; 5J49Q6B70F / Vincristine
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28. Tonomura Y, Kataoka H, Hara Y, Takamure M, Naba I, Kitauti T, Saito K, Ueno S: Clinical analysis of paraneoplastic encephalitis associated with ovarian teratoma. J Neurooncol; 2007 Sep;84(3):287-92
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  • The mean time from the onset of OTE to tumor diagnosis was 19.6+/-22.1 weeks.
  • Twelve patients showed abnormalities on cranial MRI, involving areas such as the temporal regions (seven patients) or brainstem (four patients).
  • In addition to tumor resection, 17 patients received some type of immunotherapy: 17 patients received corticosteroids, 10 received intravenous immunoglobulins, two received cyclophosphamide, seven received plasma exchange.
  • [MeSH-minor] Adolescent. Adult. Arrhythmias, Cardiac / etiology. Brain / pathology. Female. Humans. Hypoventilation / etiology. Magnetic Resonance Imaging. Mental Disorders / etiology. Seizures / etiology. Sialorrhea / etiology

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  • [Cites] Acta Paediatr. 2003 Apr;92(4):506-9 [12801123.001]
  • [Cites] J Neuroophthalmol. 2004 Jun;24(2):114-8 [15179063.001]
  • [Cites] J Neurol. 1982;227(4):229-38 [6183409.001]
  • [Cites] Rev Neurol (Paris). 1994;150(4):257-65 [7863176.001]
  • [Cites] N Engl J Med. 1997 May 29;336(22):1575-86 [9164815.001]
  • [Cites] Acta Neurol Scand. 1997 Jun;95(6):367-73 [9228272.001]
  • [Cites] Int Semin Surg Oncol. 2004 Nov 10;1(1):11 [15537431.001]
  • [Cites] J Neurooncol. 2006 Dec;80(3):309-12 [16944314.001]
  • [Cites] Pediatr Radiol. 2005 Jul;35(7):694-7 [15723218.001]
  • [Cites] Can J Neurol Sci. 1999 Nov;26(4):317-20 [10563220.001]
  • [Cites] J Neurooncol. 1998 Mar;37(1):63-6 [9525839.001]
  • [Cites] Ann Neurol. 2001 Jul;50(1):73-8 [11456313.001]
  • [Cites] Ann Neurol. 2005 Oct;58(4):594-604 [16178029.001]
  • [Cites] Lancet. 1997 Aug 16;350(9076):488 [9274586.001]
  • [Cites] J Child Neurol. 1997 Jun;12(4):276-81 [9203071.001]
  • [Cites] J Neurooncol. 2007 Jan;81(1):71-4 [16807779.001]
  • [Cites] Brain. 2005 Aug;128(Pt 8):1764-77 [15888538.001]
  • [Cites] Ann Neurol. 2007 Jan;61(1):25-36 [17262855.001]
  • [Cites] J Neurol Neurosurg Psychiatry. 2007 Apr;78(4):381-5 [16980333.001]
  • [Cites] Brain. 2001 Dec;124(Pt 12):2417-26 [11701596.001]
  • [Cites] Clin Nucl Med. 2003 Nov;28(11):893-6 [14578703.001]
  • [Cites] J Neurol Neurosurg Psychiatry. 1974 Oct;37(10):1166-76 [4374509.001]
  • (PMID = 17431543.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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29. Tibbetts KM, Emnett RJ, Gao F, Perry A, Gutmann DH, Leonard JR: Histopathologic predictors of pilocytic astrocytoma event-free survival. Acta Neuropathol; 2009 Jun;117(6):657-65
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  • Pilocytic astrocytoma (PA) is the most common pediatric brain tumor.
  • Most arise in the cerebellum, but they also can develop in the brainstem and optic nerve, where gross total resection (GTR) is not possible.
  • Lastly, we did find a statistical trend between EFS and the number of CD68+ cells, suggesting that non-neoplastic elements of the tumor microenvironment may influence subsequent growth and clinical recurrence.
  • [MeSH-major] Astrocytoma / pathology. Brain Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Antigens, CD / metabolism. Antigens, Differentiation, Myelomonocytic / metabolism. Brain / pathology. Brain / physiopathology. Child. Child, Preschool. Disease-Free Survival. Female. Humans. Immunohistochemistry. Infant. Male. Mitotic Index. Retrospective Studies. Signal Transduction. Tumor Suppressor Protein p53 / metabolism. Young Adult


30. Grayeli AB, Kalamarides M, Bouccara D, Ambert-Dahan E, Sterkers O: Auditory brainstem implant in neurofibromatosis type 2 and non-neurofibromatosis type 2 patients. Otol Neurotol; 2008 Dec;29(8):1140-6
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  • [Title] Auditory brainstem implant in neurofibromatosis type 2 and non-neurofibromatosis type 2 patients.
  • OBJECTIVE: To evaluate the auditory brainstem implant (ABI) performances in neurofibromatosis type 2 (NF2) and non-NF2 patients.
  • PATIENTS: Between 1996 and 2006, 31 adult patients (mean age, 41 yr; range, 17-65 yr) were implanted with a 21-electrode Nucleus device (Cochlear Inc., Lane Cove, Australia).
  • INTERVENTION: Auditory brainstem implant was placed through a translabyrinthine or a retrosigmoid approach.
  • MAIN OUTCOME MEASURES: Auditory brainstem implant was evaluated by open-set words and sentences in sound, vision, and sound-plus-vision modes.
  • CONCLUSION: A clear benefit of ABI could be evidenced in NF2 patients, especially in case of small tumor and short duration of hearing loss.
  • Auditory brainstem implant may also be indicated in patients with bilateral profound hearing loss and a predictable failure of cochlear implantation.
  • [MeSH-major] Auditory Brain Stem Implantation / methods. Hearing Aids. Neurofibromatosis 2 / surgery. Prosthesis Implantation / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Cochlea / pathology. Cohort Studies. Ear, Inner / abnormalities. Electric Stimulation. Evoked Potentials, Auditory / physiology. Humans. Meningitis / complications. Middle Aged. Neuroma, Acoustic / surgery. Ossification, Heterotopic / etiology. Otosclerosis / complications. Retrospective Studies. Young Adult

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  • (PMID = 18849886.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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31. Kilani B, Ammari L, Tiouiri H, Kanoun F, Ben Romdhane K, Ben Chaabane T: [Transverse myelitis revealing Hodgkin disease]. Presse Med; 2006 Apr;35(4 Pt 1):615-7
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  • The computed tomography examination of thorax and abdomen showed swelling in deep lymph nodes and the brain MRI showed what appeared to be transverse myelitis.
  • The brainstem biopsy was normal; the hepatic biopsy showed liver infiltration by Sternberg cells.
  • Their association with a tumor suggests this diagnosis even when the neurological signs are nonspecific.
  • They may affect either the brain or the brainstem.
  • [MeSH-minor] Adult. Diagnosis, Differential. Fatal Outcome. Humans. Magnetic Resonance Imaging. Male. Tomography, X-Ray Computed

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  • (PMID = 16614604.001).
  • [ISSN] 0755-4982
  • [Journal-full-title] Presse medicale (Paris, France : 1983)
  • [ISO-abbreviation] Presse Med
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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32. Tufarelli D, Meli A, Alesii A, De Angelis E, Badaracco C, Falcioni M, Sanna M: Quality of life after acoustic neuroma surgery. Otol Neurotol; 2006 Apr;27(3):403-9
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  • OBJECTIVE: The aim of this study is to assess patients' quality of life after acoustic neuroma surgery, and if some patients' characteristics, parameters of tumor and surgical parameters affect patients' quality of life.
  • Our data indicate that an early surgical approach for intrameatal tumor is better than waiting for an increase in the tumor size.
  • A "wait-and-scan" strategy for extrameatal neuromas which do not affect the brainstem is preferable, since these patients have a worsening of their quality of life after surgery independently of the tumor size.
  • [MeSH-minor] Adult. Aged. Female. Follow-Up Studies. Health Status. Hearing Loss / etiology. Hearing Loss / psychology. Humans. Male. Middle Aged. Retrospective Studies. Surveys and Questionnaires

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  • (PMID = 16639281.001).
  • [ISSN] 1531-7129
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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33. Wang CC, Zhang JT, Liu AL: [Surgical management of brain-stem gliomas: a retrospective analysis of 311 cases]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2005 Feb;27(1):7-12
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  • [Title] [Surgical management of brain-stem gliomas: a retrospective analysis of 311 cases].
  • OBJECTIVE: To further study the clinical features, diagnosis, and surgery outcome of brain-stem gliomas.
  • METHODS: Totally 311 patients with brain-stem gliomas received surgery operations in our hospital from 1980 to the end of 2001.
  • RESULTS: Different brain-stem gliomas showed different growth patterns.
  • In this series, total excision rate of the tumor was 40.5%, subtotal 29.9%, partial 29.6%, and operative mortality 1.3%.
  • None of brain-stem glioblastoma patients survived up to 5 years.
  • CONCLUSIONS: The histology and growth pattern of brainstem gliomas varies.
  • The patients with well-differentiated gliomas of brain-stem may be cured by microsurgical removal.
  • [MeSH-major] Astrocytoma / surgery. Brain Stem Neoplasms / surgery. Ependymoma / surgery. Glioblastoma / surgery. Neurosurgical Procedures
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Female. Follow-Up Studies. Humans. Infant. Magnetic Resonance Imaging. Male. Mesencephalon / surgery. Microsurgery / methods. Middle Aged. Pons / surgery. Retrospective Studies. Survival Rate

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  • (PMID = 15782484.001).
  • [ISSN] 1000-503X
  • [Journal-full-title] Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
  • [ISO-abbreviation] Zhongguo Yi Xue Ke Xue Yuan Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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34. Gokcan MK, Batikhan H, Calguner M, Tataragasi AI: Unilateral hearing loss as a presenting manifestation of granulocytic sarcoma (chloroma). Otol Neurotol; 2006 Jan;27(1):106-9
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  • After confirmation of her audiometric findings with auditory brainstem responses, the patient was put on a treatment regimen for sudden hearing loss.
  • As increased intracranial pressure symptoms developed subsequently, subtotal tumor resection was performed.
  • [MeSH-minor] Adult. Auditory Threshold. Evoked Potentials, Auditory, Brain Stem / physiology. Facial Paralysis / etiology. Female. Humans. Leukemia, Promyelocytic, Acute / complications. Leukemia, Promyelocytic, Acute / therapy. Magnetic Resonance Imaging. Treatment Outcome. Vocal Cord Paralysis / etiology

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  • (PMID = 16371856.001).
  • [ISSN] 1531-7129
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 15
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35. Szkandera J, Ploner F, Bauernhofer T, Kasparek AK, Payer F, Balic M, Knechtel G, Gerger A, Gallè G, Samonigg H, Hofmann G: Paraneoplastic limbic encephalitis in a patient with extragonadal choriocarcinoma--significance of onconeural antibodies. Onkologie; 2010;33(8-9):452-4
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  • BACKGROUND: Paraneoplastic limbic or brainstem encephalitis is considered to be an autoimmune-mediated disorder of the nervous system associated with different types of cancer including germ cell tumors.
  • Neurologic tests, brain imaging, and blood chemistry tests failed to determine the cause of the symptoms.
  • CONCLUSIONS: Patients with symptoms of limbic or brainstem encephalitis, especially young men, should be tested for anti-Ma2 antibodies in the serum to elucidate their origin.
  • The detection of these antibodies supports the diagnosis of a paraneoplastic syndrome, and may lead to the earlier identification of an otherwise hidden extragonadal germ cell tumor.
  • [MeSH-major] Antibodies, Neoplasm / immunology. Antigens, Neoplasm / immunology. Limbic Encephalitis / diagnosis. Limbic Encephalitis / immunology. Nerve Tissue Proteins / immunology. Peritoneal Neoplasms / diagnosis. Peritoneal Neoplasms / immunology
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Male. Neoplasms, Gonadal Tissue

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  • [Copyright] Copyright © 2010 S. Karger AG, Basel.
  • (PMID = 20838061.001).
  • [ISSN] 1423-0240
  • [Journal-full-title] Onkologie
  • [ISO-abbreviation] Onkologie
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Antibodies, Neoplasm; 0 / Antigens, Neoplasm; 0 / Ma2 antigen; 0 / Nerve Tissue Proteins
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36. Tasić G, Jovanović V, Radulović D, Djurović B, Piscević I, Nikolić I, Janićijević M: [Clinical characteristics and results of surgical treatment of petroclival meningioma]. Srp Arh Celok Lek; 2006 May-Jun;134(5-6):183-6
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  • The following parameters were analyzed: size of tumor, relation with bone and neurovascular structures, preoperative condition, degree of surgical radicalism and postoperative outcome.
  • RESULTS: The size of tumor was classified in four groups.
  • At the time of diagnostic procedures (based on CT and MRI), 20 tumors were in contact with brainstem, 9 compressed the brainstem, and 6 obstructed the IV ventricle.
  • The tumor size (III-IV) and brainstem compression were found to be statistically significant (p<0.05) as predisposed factors of deficit prolongation.
  • [MeSH-minor] Adult. Aged. Cranial Fossa, Posterior. Female. Humans. Male. Middle Aged

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  • (PMID = 16972402.001).
  • [ISSN] 0370-8179
  • [Journal-full-title] Srpski arhiv za celokupno lekarstvo
  • [ISO-abbreviation] Srp Arh Celok Lek
  • [Language] srp
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Serbia and Montenegro
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37. Brodsky JR, Smith TW, Litofsky S, Lee DJ: Lipoma of the cerebellopontine angle. Am J Otolaryngol; 2006 Jul-Aug;27(4):271-4
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  • Despite conservative therapy, the patient developed progressive hemifacial spasm, and a suboccipital craniotomy approach was used to debulk the tumor, which encased cranial nerves V, VII, VIII, IX, X, and XI.
  • Partial surgical resection is indicated only to alleviate intractable cranial neuropathies or relieve brainstem compression.
  • [MeSH-minor] Adult. Craniotomy. Face. Female. Hearing Loss, Sensorineural / etiology. Hemifacial Spasm / etiology. Humans. Magnetic Resonance Imaging. Synkinesis / etiology

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  • (PMID = 16798407.001).
  • [ISSN] 0196-0709
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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38. Lustig LR, Yeagle J, Driscoll CL, Blevins N, Francis H, Niparko JK: Cochlear implantation in patients with neurofibromatosis type 2 and bilateral vestibular schwannoma. Otol Neurotol; 2006 Jun;27(4):512-8
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  • PATIENTS: Seven patients with NF2 and bilateral vestibular schwannoma who lost hearing in at least one ear after treatment of their tumor (surgery or radiation therapy).
  • Hearing loss was due to surgical excision of tumor (n=5) or gamma-knife radiotherapy (n=2).
  • These results compare favorably to the auditory brainstem implant offering an alternative for hearing rehabilitation in patients with NF2.
  • [MeSH-minor] Adolescent. Adult. Audiometry, Pure-Tone. Auditory Threshold / physiology. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Radiosurgery / adverse effects. Retrospective Studies. Treatment Outcome


39. Schipani S, Jain R, Shah K, Rock JP, Movsas B, Rosenblum M, Ryu S: Clinical, dosimetric, and radiographic correlation of radiation injury involving the brainstem and the medial temporal lobes following stereotactic radiotherapy for neoplasms of central skull base. J Neurooncol; 2010 Jun;98(2):177-84
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  • [Title] Clinical, dosimetric, and radiographic correlation of radiation injury involving the brainstem and the medial temporal lobes following stereotactic radiotherapy for neoplasms of central skull base.
  • Mean time interval between SRT and detection of RI was 9 +/- 3, 18.5 +/- 5, and 13.5 months for brainstem, temporal lobe, and cerebellum/labyrinth lesions, respectively.
  • RI can occur around the skull base because of irregular shape of target tumor, its close proximity to normal brain parenchyma, and inhomogeneity of dose distribution.
  • Brainstem lesions occurred earlier than temporal lobe RI.
  • The majority of the RI lesions, not mixed with the tumor in this study, showed radiographic and clinical improvement with steroid and symptomatic treatments.
  • [MeSH-major] Brain Stem / pathology. Radiation Injuries / pathology. Radiosurgery / adverse effects. Skull Base Neoplasms / surgery. Temporal Lobe / pathology
  • [MeSH-minor] Adult. Aged. Female. Humans. Image Processing, Computer-Assisted / methods. Magnetic Resonance Imaging / methods. Male. Middle Aged. Radiometry / methods. Radiotherapy Dosage. Time Factors

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  • [Cites] Arterioscler Thromb Vasc Biol. 2001 Aug;21(8):1327-32 [11498461.001]
  • [Cites] Cancer. 2003 Apr 15;97(8):2013-8 [12673732.001]
  • [Cites] Nucl Med Commun. 1999 May;20(5):411-7 [10404525.001]
  • [Cites] AJNR Am J Neuroradiol. 2005 Sep;26(8):1967-72 [16155144.001]
  • [Cites] Circulation. 2003 Jul 29;108(4):426-31 [12860913.001]
  • [Cites] Cancer. 1997 Nov 15;80(10):2005-12 [9366305.001]
  • [Cites] Stereotact Funct Neurosurg. 2008;86(6):359-66 [18854663.001]
  • [Cites] AJNR Am J Neuroradiol. 2001 Apr;22(4):613-24 [11290467.001]
  • [Cites] Stereotact Funct Neurosurg. 1998 Oct;70 Suppl 1:229-36 [9782255.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1996 Dec 1;36(5):1055-63 [8985027.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2000 Mar 15;46(5):1143-8 [10725624.001]
  • [Cites] Radiother Oncol. 1997 Jun;43(3):275-80 [9215787.001]
  • [Cites] J Neurosurg. 2001 Jun;94(6):899-904 [11409517.001]
  • [Cites] Neurosurgery. 2007 Oct;61(4):778-86; discussion 786-7 [17986939.001]
  • [Cites] J Clin Oncol. 1990 Jul;8(7):1277-80 [2358840.001]
  • [Cites] Otolaryngol Head Neck Surg. 2004 Jun;130(6):690-7 [15195054.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1998 Jan 15;40(2):273-8 [9457809.001]
  • [Cites] J Nucl Med. 2000 Nov;41(11):1861-7 [11079496.001]
  • [Cites] Am J Otolaryngol. 2007 Sep-Oct;28(5):338-41 [17826537.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1997 Jun 1;38(3):485-90 [9231670.001]
  • [Cites] Magn Reson Imaging Clin N Am. 2003 Aug;11(3):403-13 [14768726.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2004 Jul 1;59(3):796-808 [15183483.001]
  • [Cites] Surg Neurol. 2009 Aug;72(2):162-7; discussion 167-8 [18786715.001]
  • [Cites] Surg Neurol. 1978 Nov;10(5):281-90 [364708.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1999 Oct 1;45(3):699-705 [10524425.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2007 Feb 1;67(2):323-6 [17236958.001]
  • [Cites] J Neurooncol. 2007 Apr;82(2):119-24 [17004100.001]
  • [Cites] Int J Cancer. 2001 Jun 20;96(3):191-7 [11410888.001]
  • [Cites] Radiology. 2000 Nov;217(2):377-84 [11058631.001]
  • [Cites] Neurosurgery. 2007 Mar;60(3):E579; discussion E579 [17327770.001]
  • [Cites] Ann Neurol. 2003 Jun;53(6):743-51 [12783420.001]
  • [Cites] Radiat Res. 2004 Feb;161(2):137-42 [14731077.001]
  • [Cites] J Neurosurg. 1990 Oct;73(4):502-12 [2204689.001]
  • [Cites] J Neurol Sci. 2008 Dec 15;275(1-2):164-6 [18804790.001]
  • [Cites] Neurol Med Chir (Tokyo). 2003 Aug;43(8):391-5 [12968806.001]
  • [Cites] J Neuroophthalmol. 2004 Sep;24(3):195-9 [15348983.001]
  • (PMID = 20376551.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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40. Riina HA, Knopman J, Greenfield JP, Fralin S, Gobin YP, Tsiouris AJ, Souweidane MM, Boockvar JA: Balloon-assisted superselective intra-arterial cerebral infusion of bevacizumab for malignant brainstem glioma. A technical note. Interv Neuroradiol; 2010 Mar;16(1):71-6
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  • [Title] Balloon-assisted superselective intra-arterial cerebral infusion of bevacizumab for malignant brainstem glioma. A technical note.
  • Malignant brainstem gliomas (BSG) are rare tumors in adults, associated with a grim prognosis and limited treatment options.
  • Intravenous (IV) administration of bevacizumab (Avastin, Genentech Pharmaceuticals) has been shown to be active in the treatment of some enhancing malignant brainstem gliomas.
  • In addition, the percentage of IV drug that reaches the tumor site is restricted by the blood brain barrier (BBB).Weill Cornell Brain Tumor Center, Department of Neurosurgery, Weill Cornell Medical College of Cornell University: New York, NY, USA.
  • This technical report describes our protocol in performing superselective intra-arterial cerebral infusion (SIACI) of bevacizumab using endovascular balloon-assistance in the top of the basilar artery in a patient with a recurrent malignant brainstem glioma.
  • This method of drug delivery may have important implications in the treatment of both adult and pediatric brainstem gliomas.
  • [MeSH-major] Antibodies, Monoclonal / administration & dosage. Brain Stem Neoplasms / diagnostic imaging. Brain Stem Neoplasms / drug therapy. Catheterization / methods. Glioma / diagnostic imaging. Glioma / drug therapy. Infusions, Intra-Arterial / methods
  • [MeSH-minor] Adult. Antibodies, Monoclonal, Humanized. Antineoplastic Agents / administration & dosage. Bevacizumab. Humans. Male. Radiography. Treatment Outcome

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  • [Cites] Radiology. 2001 Mar;218(3):724-32 [11230646.001]
  • [Cites] J Exp Ther Oncol. 2009;8(2):145-50 [20192120.001]
  • [Cites] Neurosurgery. 1985 Sep;17(3):419-23 [3930991.001]
  • [Cites] Neurosurgery. 1986 Oct;19(4):573-82 [3097567.001]
  • [Cites] J Neurooncol. 1987;4(3):195-207 [3104548.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1998 Jan 15;40(2):265-71 [9457808.001]
  • [Cites] J Neurooncol. 1998 Nov;40(2):171-7 [9892099.001]
  • [Cites] Arch Neurol. 1999 Apr;56(4):421-5 [10199329.001]
  • [Cites] Neurology. 2006 Apr 25;66(8):1258-60 [16636248.001]
  • [Cites] J Neurooncol. 2006 May;77(3):279-84 [16314949.001]
  • [Cites] Pediatr Blood Cancer. 2006 Aug;47(2):174-82 [16086410.001]
  • [Cites] Clin Cancer Res. 2007 Feb 15;13(4):1253-9 [17317837.001]
  • [Cites] J Clin Oncol. 2007 Oct 20;25(30):4714-21 [17947718.001]
  • [Cites] J Neurol. 2008 Feb;255(2):171-7 [18293027.001]
  • [Cites] J Neurooncol. 2008 Jul;88(3):339-47 [18389177.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2008 Aug 1;71(5):1372-80 [18355978.001]
  • [Cites] Neuro Oncol. 2008 Jun;10(3):355-60 [18436627.001]
  • [Cites] J Clin Oncol. 2009 Oct 1;27(28):4733-40 [19720927.001]
  • [Cites] Brain. 2001 Dec;124(Pt 12):2528-39 [11701605.001]
  • (PMID = 20377982.001).
  • [ISSN] 1591-0199
  • [Journal-full-title] Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences
  • [ISO-abbreviation] Interv Neuroradiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 0 / Antineoplastic Agents; 2S9ZZM9Q9V / Bevacizumab
  • [Other-IDs] NLM/ PMC3277958
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41. Han DY, Yu LM, Yu LM, Ji F, Young WY, Yang SM: Acoustic neuroma surgery for preservation of hearing: technique and experience in the Chinese PLA General Hospital. Acta Otolaryngol; 2010 May;130(5):583-92
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  • From July 2003 to July 2007, intraoperative auditory monitoring using auditory brainstem response (ABR) and electrocochleography (EcochG) was conducted in 18 of 138 patients undergoing surgery for acoustic neuroma who had preoperative hearing.
  • Intraoperative monitoring revealed that the waveform was influenced when the posterior labium of the internal acoustic meatus was ground and drilled, or when traction or electrocoagulation was performed near the opening of the internal acoustic meatus, especially when the internal auditory artery was clamped, the tumor in the internal acoustic meatus was treated, and the arachnoid vessels in the inner-most layer of the tumor surface were clamped or electrocoagulated.
  • [MeSH-minor] Adolescent. Adult. Facial Nerve Diseases / etiology. Female. Hearing Tests. Humans. Male. Middle Aged. Retrospective Studies. Young Adult

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  • (PMID = 20406132.001).
  • [ISSN] 1651-2251
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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42. Esposito F, Becker DP, Villablanca JP, Kelly DF: Endonasal transsphenoidal transclival removal of prepontine epidermoid tumors: technical note. Neurosurgery; 2005 Apr;56(2 Suppl):E443; discussion E443
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  • In each patient, magnetic resonance imaging showed a large T1 hypointense/T2 hyperintense mass occupying the posterior suprasellar, premesencephalic, and prepontine cisterns, with significant mass effect on the brainstem.
  • Both patients underwent an endonasal transsphenoidal transclival cranial base tumor removal with the operating microscope and endoscopic assistance.
  • RESULTS: At 1 year after surgery, both patients have improved compared with their preoperative neurological state, and volume analysis of preoperative and 1-year postoperative magnetic resonance imaging scans confirm a marked reduction in mass effect on the brainstem, with a 78% tumor removal in one patient and 76% removal in the other.
  • CONCLUSION: The endonasal approach offers a minimally invasive, anatomically direct route for removing prepontine epidermoid tumors that obviates brain retraction.
  • Inadequate repair of clival dural defects remains the greatest potential pitfall in attempting transsphenoidal transclival tumor removal.
  • [MeSH-major] Brain Neoplasms / surgery. Carcinoma, Squamous Cell / surgery. Cranial Fossa, Posterior. Nasal Cavity. Neurosurgical Procedures. Pons
  • [MeSH-minor] Adult. Escherichia coli Infections / etiology. Humans. Magnetic Resonance Imaging. Male. Meningitis, Bacterial / etiology. Middle Aged. Minimally Invasive Surgical Procedures. Neuroendoscopy. Reoperation. Sphenoid Bone. Treatment Outcome

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  • (PMID = 15794847.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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43. Matsumura R, Umemiya K, Sugiyama T, Sueishi M, Umibe T, Ichikawa K, Yoshimura M, Study Group on Nephrology at the National Hospital Organization of Japan: Anti-tumor necrosis factor therapy in patients with difficult-to-treat lupus nephritis: a prospective series of nine patients. Clin Exp Rheumatol; 2009 May-Jun;27(3):416-21
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  • [Title] Anti-tumor necrosis factor therapy in patients with difficult-to-treat lupus nephritis: a prospective series of nine patients.
  • In one patient in whom the steroid dosage was increased due to poor response to anti-TNF-alpha therapy, brainstem infarction occurred four months later.
  • [MeSH-major] Antibodies, Monoclonal / therapeutic use. Antirheumatic Agents / therapeutic use. Lupus Nephritis / drug therapy. Tumor Necrosis Factor-alpha / antagonists & inhibitors
  • [MeSH-minor] Adult. Antibodies, Anti-Idiotypic / blood. DNA / immunology. Female. Follow-Up Studies. Humans. Infliximab. Lupus Erythematosus, Systemic / blood. Lupus Erythematosus, Systemic / complications. Lupus Erythematosus, Systemic / physiopathology. Male. Middle Aged. Prospective Studies. Proteinuria / etiology. Proteinuria / prevention & control. Severity of Illness Index. Treatment Outcome

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  • (PMID = 19604433.001).
  • [ISSN] 0392-856X
  • [Journal-full-title] Clinical and experimental rheumatology
  • [ISO-abbreviation] Clin. Exp. Rheumatol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Antibodies, Anti-Idiotypic; 0 / Antibodies, Monoclonal; 0 / Antirheumatic Agents; 0 / Tumor Necrosis Factor-alpha; 9007-49-2 / DNA; B72HH48FLU / Infliximab
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44. Phillips DJ, Kobylarz EJ, De Peralta ET, Stieg PE, Selesnick SH: Predictive factors of hearing preservation after surgical resection of small vestibular schwannomas. Otol Neurotol; 2010 Dec;31(9):1463-8
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  • Potential predictive factors of hearing preservation included patient demographics, tumor characteristics, audiometric data, and intraoperative brainstem auditory evoked response (BAER) monitoring.
  • Patient age, sex, preoperative hearing status, tumor size, laterality, extent of internal auditory canal involvement, surgical approach, wave V latency, and wave V amplitude were not predictive of hearing preservation.
  • [MeSH-minor] Adolescent. Adult. Aged. Audiometry. Cranial Fossa, Middle / surgery. Evoked Potentials, Auditory, Brain Stem / physiology. Female. Humans. Magnetic Resonance Imaging. Male. Microsurgery. Middle Aged. Otologic Surgical Procedures. Predictive Value of Tests. Prognosis. Retrospective Studies. Treatment Outcome. Young Adult

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  • (PMID = 21113983.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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45. Hua C, Bass JK, Khan R, Kun LE, Merchant TE: Hearing loss after radiotherapy for pediatric brain tumors: effect of cochlear dose. Int J Radiat Oncol Biol Phys; 2008 Nov 1;72(3):892-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hearing loss after radiotherapy for pediatric brain tumors: effect of cochlear dose.
  • PURPOSE: To determine the effect of cochlear dose on sensorineural hearing loss in pediatric patients with brain tumor treated by using conformal radiation therapy (CRT).
  • PATIENTS AND METHODS: We studied 78 pediatric patients (155 ears) with localized brain tumors treated in 1997-2001 who had not received platinum-based chemotherapy and were followed up for at least 48 months.
  • They were evaluated prospectively by means of serial pure-tone audiograms (250 Hz-8 kHz) and/or auditory brainstem response before and every 6 months after CRT.
  • In the absence of other factors, including ototoxic chemotherapy, increase in cochlear dose correlates positively with hearing loss in pediatric patients with brain tumor.
  • [MeSH-major] Audiometry, Pure-Tone. Brain Neoplasms / radiotherapy. Cochlea / radiation effects. Hearing Loss, Sensorineural / radionuclide imaging. Radiotherapy / adverse effects
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Female. Follow-Up Studies. Humans. Incidence. Male. Radiotherapy Dosage. Retrospective Studies. Time Factors. Young Adult


46. Noshita N, Kumabe T, Kayama T, Tominaga T: [Choroid plexus tumors: report of 7 cases in a single institution]. No Shinkei Geka; 2006 Jan;34(1):73-81
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  • Subtotal resection was achieved in four patients, one of whom underwent second surgery resulting in total resection, and one patient died of respiratory disturbance after the third operation because of regrowth of the tumor.
  • Complete excision could not be achieved in 3 of the 5 tumors located in the fourth ventricle because of extension to the brainstem.
  • [MeSH-minor] Adult. Child, Preschool. Female. Humans. Infant. Magnetic Resonance Imaging. Male

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  • (PMID = 16440700.001).
  • [ISSN] 0301-2603
  • [Journal-full-title] No shinkei geka. Neurological surgery
  • [ISO-abbreviation] No Shinkei Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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47. Burzynski SR, Janicki TJ, Weaver RA, Burzynski B: Targeted therapy with antineoplastons A10 and AS2-1 of high-grade, recurrent, and progressive brainstem glioma. Integr Cancer Ther; 2006 Mar;5(1):40-7
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  • [Title] Targeted therapy with antineoplastons A10 and AS2-1 of high-grade, recurrent, and progressive brainstem glioma.
  • BACKGROUND: Brainstem glioma carries the worst prognosis of all malignancies of the brain.
  • Most patients with brainstem glioma fail standard radiation therapy and chemotherapy and do not survive longer than 2 years.
  • Treatment is even more challenging when an inoperable tumor is of high-grade pathology (HBSG).
  • CONCLUSION: Antineoplastons contributed to more than a 5-year survival in recurrent diffuse intrinsic glioblastomas and anaplastic astrocytomas of the brainstem in a small group of patients.
  • [MeSH-major] Benzeneacetamides / administration & dosage. Brain Stem Neoplasms / drug therapy. Glioma / drug therapy. Glutamine / analogs & derivatives. Neoplasm Recurrence, Local / drug therapy. Phenylacetates / administration & dosage. Piperidones / administration & dosage
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Dose-Response Relationship, Drug. Drug Administration Schedule. Drug Combinations. Female. Follow-Up Studies. Humans. Injections, Intravenous. Magnetic Resonance Imaging. Male. Maximum Tolerated Dose. Neoplasm Staging. Risk Assessment. Survival Analysis. Treatment Outcome

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  • (PMID = 16484713.001).
  • [ISSN] 1534-7354
  • [Journal-full-title] Integrative cancer therapies
  • [ISO-abbreviation] Integr Cancer Ther
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase II; Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Benzeneacetamides; 0 / Drug Combinations; 0 / Phenylacetates; 0 / Piperidones; 0RH81L854J / Glutamine; 104624-98-8 / antineoplaston AS 2-1; 91531-30-5 / antineoplaston A10
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48. Kimura M, Onozawa M, Fujisaki A, Arakawa T, Takeda K, Dalmau J, Hattori K: Anti-Ma2 paraneoplastic encephalitis associated with testicular germ cell tumor treated by carboplatin, etoposide and bleomycin. Int J Urol; 2008 Oct;15(10):942-3
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  • [Title] Anti-Ma2 paraneoplastic encephalitis associated with testicular germ cell tumor treated by carboplatin, etoposide and bleomycin.
  • Anti-Ma2-associated encephalitis is a paraneoplastic disorder that predominantly affects the limbic system, diencephalon and brainstem, and is usually associated with tumors of the testis.
  • After three courses of carboplatin, etoposide and bleomycin for metastatic testicular germ-cell tumor, all elevated tumor markers normalized and the retroperitoneal metastases disappeared, but the neurological disorder deteriorated.
  • To our knowledge, this is the first case in which orchiectomy followed by carboplatin, etoposide and bleomycin for a testicular tumor with anti-Ma2 encephalitis was performed.
  • [MeSH-major] Antigens, Neoplasm / immunology. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Neoplasms, Germ Cell and Embryonal / therapy. Nerve Tissue Proteins / immunology. Orchiectomy. Paraneoplastic Syndromes, Nervous System / immunology. Paraneoplastic Syndromes, Nervous System / therapy. Testicular Neoplasms / therapy
  • [MeSH-minor] Adult. Bleomycin / administration & dosage. Carboplatin / administration & dosage. Combined Modality Therapy. Etoposide / administration & dosage. Humans. Male

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  • (PMID = 19138287.001).
  • [ISSN] 1442-2042
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Ma2 antigen; 0 / Nerve Tissue Proteins; 11056-06-7 / Bleomycin; 6PLQ3CP4P3 / Etoposide; BG3F62OND5 / Carboplatin
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49. Stark AM, Maslehaty H, Hugo HH, Mahvash M, Mehdorn HM: Glioblastoma of the cerebellum and brainstem. J Clin Neurosci; 2010 Oct;17(10):1248-51
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  • [Title] Glioblastoma of the cerebellum and brainstem.
  • Glioblastoma multiforme (GB) is the most common and most malignant primary intracranial tumor.
  • Because of its rarity and the non-specific radiological features of iGB, it can easily be misdiagnosed as a brain metastasis, ependymoma or even as a benign lesion such as vestibular schwannoma or meningioma.
  • [MeSH-major] Brain Neoplasms / pathology. Brain Stem / pathology. Cerebellum / pathology. Glioblastoma / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Magnetic Resonance Imaging / methods. Male. Middle Aged. Retrospective Studies. Young Adult

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  • [Copyright] Copyright 2010 Elsevier Ltd. All rights reserved.
  • (PMID = 20619657.001).
  • [ISSN] 1532-2653
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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50. Ohba S, Miwa T, Kawase T: Trochlear nerve schwannoma with intratumoral hemorrhage: case report. Neurosurgery; 2006 Apr;58(4):E791; discussion E791
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  • Magnetic resonance imaging revealed an abnormal cystic lesion beside the brainstem.
  • INTERVENTION: Gross total removal of the tumor was performed via the anterior transpetrosal approach.
  • The tip of the trochlear nerve was fanned out and unified with the tumor.
  • The tumor was diagnosed as a schwannoma.
  • Magnetic resonance imaging performed 4 months later revealed no regrowth of the tumor.
  • [MeSH-minor] Adult. Humans. Male

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  • (PMID = 16575299.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 33
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51. Colletti V, Shannon R, Carner M, Veronese S, Colletti L: Outcomes in nontumor adults fitted with the auditory brainstem implant: 10 years' experience. Otol Neurotol; 2009 Aug;30(5):614-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Outcomes in nontumor adults fitted with the auditory brainstem implant: 10 years' experience.
  • OBJECTIVES: Recently, open-set speech recognition performance has been observed with electric stimulation of the brainstem in some nontumor (NT) patients.
  • These outcomes require that we reevaluate the criteria for patient selection and the rationale for expanding the application for the auditory brainstem implant (ABI) to NT adult patients with profound hearing loss.
  • MATERIALS AND METHODS: In our Department, from April 1997 to September 2007, ABIs have been implanted in 112 patients (83 adults and 29 children) with tumor (T) and NT disorders.
  • [MeSH-major] Auditory Brain Stem Implantation. Hearing Loss / surgery
  • [MeSH-minor] Adult. Cochlea / abnormalities. Cochlear Diseases / pathology. Cochlear Diseases / surgery. Cochlear Nerve / pathology. Craniocerebral Trauma / pathology. Craniocerebral Trauma / surgery. Female. Follow-Up Studies. Hearing Tests. Humans. Male. Peripheral Nervous System Diseases / pathology. Peripheral Nervous System Diseases / surgery. Retrospective Studies. Treatment Outcome


52. Tohmé A, Koussa S, Haddad-Zébouni S, El-Rassi B, Ghayad E: [Neurological manifestations of Behcet's disease: 22 cases among 170 patients]. Presse Med; 2009 May;38(5):701-9
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  • Meningoencephalitis and/or transverse myelitis were found in 57% (12/21) of cases (in association with brainstem syndrome in 2 of these cases), brainstem syndrome without meningoencephalitis in 5 cases, tumor-like syndrome in 2 cases, repetitive ischemic attacks in 1 case and cerebral venous thrombosis in one.
  • MRI, performed in 9 patients, was abnormal in 6 and showed abnormal signals distributed over the brainstem and the thalamus in 4, a tumor-like lesion and thrombosis of the left lateral sinus one each.
  • One patient who had brainstem syndrome died within 18 months because of a delayed corticosteroid treatment.
  • CONCLUSION: Within central neurological involvement in Behçet's disease, we can individualize 4 clinical aspects: meningoencephalitis (and/or myelitis), brainstem syndrome, tumor-like features and cerebral venous thrombosis.
  • Abnormalities, observed on CT Scan and MRI, by their brainstem localization and their multiplicity, should evoke the diagnosis.
  • [MeSH-minor] Adrenal Cortex Hormones / therapeutic use. Adult. Brain / pathology. Female. Humans. Immunosuppressive Agents / therapeutic use. Magnetic Resonance Imaging. Male. Middle Aged. Retrospective Studies. Sex Factors

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  • (PMID = 19062244.001).
  • [ISSN] 2213-0276
  • [Journal-full-title] Presse medicale (Paris, France : 1983)
  • [ISO-abbreviation] Presse Med
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Adrenal Cortex Hormones; 0 / Immunosuppressive Agents
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53. Wakabayashi T, Natsume A, Hatano H, Fujii M, Shimato S, Ito M, Ohno M, Ito S, Ogura M, Yoshida J: p16 promoter methylation in the serum as a basis for the molecular diagnosis of gliomas. Neurosurgery; 2009 Mar;64(3):455-61; discussion 461-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: Deoxyribonucleic acid (DNA) methylation of tumor origin can be detected in the serum/plasma of cancer patients.
  • The aim of this study was to detect aberrant p16 promoter methylation as a potential diagnostic marker in the serum of patients with diffuse glioma to differentiate between gliomas and, particularly, to differentiate those in the brainstem from others; this was done by using the modified methylation-specific polymerase chain reaction technique.
  • In addition, the serum DNA in 7 patients with a brainstem tumor (4 gliomas, 1 schwannoma, 1 cavernous angioma, and 1 ependymoma) was analyzed.
  • Similar methylations were detected in the serum of 9 (75%) of the 12 patients with aberrant methylation in the tumor tissues.
  • Additionally, p16 promoter methylation in the serum was observed in all brainstem astrocytoma cases, but not in other cases.
  • [MeSH-major] Brain Neoplasms / diagnosis. Brain Neoplasms / genetics. Cyclin-Dependent Kinase Inhibitor p16 / genetics. DNA, Neoplasm / blood. DNA, Neoplasm / genetics. Genes, p16. Glioma / diagnosis. Glioma / genetics
  • [MeSH-minor] Adolescent. Adult. Aged. Child. DNA Methylation / genetics. Female. Genetic Predisposition to Disease / genetics. Humans. Male. Middle Aged. Reproducibility of Results. Sensitivity and Specificity. Young Adult

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  • (PMID = 19240607.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / DNA, Neoplasm
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54. Miyatake S, Tamura Y, Kawabata S, Iida K, Kuroiwa T, Ono K: Boron neutron capture therapy for malignant tumors related to meningiomas. Neurosurgery; 2007 Jul;61(1):82-90; discussion 90-1
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  • RESULTS: Five of the six patients who underwent BPA-PET analysis showed good BPA uptake, with a greater than 2.7 tumor-to-healthy brain ratio.
  • The atypical meningioma case showed a tumor-to-healthy brain ratio of 2.0.
  • The original tumor sizes were between 13.6 and 109 ml.
  • In this patient, a huge atypical meningioma arose from the falcotentorial junction and extended to the bilateral occipital lobes and brainstem; visual problems worsened after repetitive BNCT, with an increase in peritumoral edema.
  • [MeSH-major] Boron Neutron Capture Therapy / methods. Brain Neoplasms / radionuclide imaging. Brain Neoplasms / radiotherapy. Meningeal Neoplasms / radiotherapy
  • [MeSH-minor] Adult. Brain Injuries / etiology. Brain Injuries / radionuclide imaging. Female. Humans. Male. Radiation Injuries / etiology. Radiation Injuries / radionuclide imaging. Treatment Outcome

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  • (PMID = 17621022.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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55. Dea N, Borduas M, Kenny B, Fortin D, Mathieu D: Safety and efficacy of Gamma Knife surgery for brain metastases in eloquent locations. J Neurosurg; 2010 Dec;113 Suppl:79-83
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Safety and efficacy of Gamma Knife surgery for brain metastases in eloquent locations.
  • OBJECT: Brain metastases are the most frequently occurring cerebral tumors.
  • Gamma Knife surgery (GKS) is a recognized treatment modality for brain metastases.
  • This study was undertaken to assess the safety and efficacy of GKS, specifically for brain metastases in eloquent locations.
  • METHODS: Charts of patients harboring brain metastases that were treated by GKS at the Centre Hospitalier Universitaire de Sherbrooke between August 2004 and April 2008 were reviewed.
  • Planning images were assessed by an independent neurosurgeon to assess tumor location.
  • Eloquent locations included the primary motor, somatosensory, speech, and visual cortices; the basal ganglia; the thalamus; and the brainstem.
  • Data on survival, tumor response, and complications were analyzed and compared with data published on surgical treatment of these lesions.
  • Non-small cell lung cancer was the most common primary tumor (63.2% of metastases), followed by small cell lung (8.4%), breast (7.4%), colorectal (5.3%), and renal cell (4.2%) cancers, as well as melanoma (4.2%).
  • The median dose to the tumor margin was 18 Gy (range 14-24 Gy).
  • The median time to tumor progression was 16 months.
  • CONCLUSIONS: Gamma Knife surgery is safe and effective for brain metastases located in eloquent areas.
  • [MeSH-major] Brain Neoplasms / secondary. Brain Neoplasms / surgery. Radiosurgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Disease Progression. Female. Humans. Kaplan-Meier Estimate. Karnofsky Performance Status. Magnetic Resonance Imaging. Male. Middle Aged. Nervous System Diseases / epidemiology. Nervous System Diseases / etiology. Neuropsychological Tests. Postoperative Complications / epidemiology. Regression Analysis. Safety. Survival Analysis. Treatment Outcome

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  • (PMID = 21218534.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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56. Yong RL, Westerberg BD, Dong C, Akagami R: Length of tumor-cochlear nerve contact and hearing outcome after surgery for vestibular schwannoma. J Neurosurg; 2008 Jan;108(1):105-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Length of tumor-cochlear nerve contact and hearing outcome after surgery for vestibular schwannoma.
  • OBJECTIVES: Tumor size is likely to be a major determinant of hearing preservation after surgery for vestibular schwannoma.
  • Findings in some large case series have not supported this concept, possibly due to variation in the technique used for tumor measurement.
  • The authors sought to determine if the length of tumor-cochlear nerve contact was predictive of hearing outcome in adults undergoing resection of a vestibular schwannoma.
  • Magnetic resonance images were reviewed and used to calculate the length of tumor-cochlear nerve contact.
  • Univariate analysis revealed that extracanalicular length of tumor-cochlear nerve contact (p = 0.0365), preoperative hearing class (p = 0.028), I-V interpeak latency of the brainstem auditory evoked potential (p = 0.021), and the interaural I-V interpeak latency difference (p = 0.018) were predictive of hearing outcome.
  • CONCLUSIONS: Vestibular schwannomas with greater lengths of tumor-cochlear nerve contact increase a patient's risk for hearing loss after surgery with attempted hearing preservation.
  • [MeSH-minor] Adult. Audiometry. Cohort Studies. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Predictive Value of Tests. Recovery of Function. Retrospective Studies. Risk Factors. Treatment Outcome

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  • (PMID = 18173318.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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57. Riffaud L, Saikali S, Leray E, Hamlat A, Haegelen C, Vauleon E, Lesimple T: Survival and prognostic factors in a series of adults with medulloblastomas. J Neurosurg; 2009 Sep;111(3):478-87
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  • OBJECT: In this article, the authors report their experience in the management of adult patients with medulloblastoma at their institution to identify prognostic factors important for survival and disease control.
  • Staging according to the Chang classification showed 4 patients with tumors invading the brainstem (2 with Stage T3b and 2 with Stage T4), 3 patients with metastases (2 with Stage M2 and 1 with Stage M3), and 1 patient in whom the stage was unknown (Stage MX) who died 10 days postoperatively.
  • Patient age, duration of symptoms, Karnofsky Performance Scale score at presentation, hydrocephalus, tumor location, brainstem invasion, extent of resection, histological subtype, preradiotherapy chemotherapy, risk group, and period of presentation were not significant variables.
  • Eleven patients suffered tumor recurrence within a median time of 4.2 years.
  • All patients in whom the tumor recurred have died despite aggressive treatments.
  • Tumor recurrences should be treated with aggressive therapies as some patients may have sustained response.
  • [MeSH-minor] Adolescent. Adult. Disease-Free Survival. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Neoplasm Staging. Prognosis. Quality of Life. Sex Factors. Survival Rate

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  • (PMID = 19231932.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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58. Hussain A, Brown PD, Stafford SL, Pollock BE: Stereotactic radiosurgery for brainstem metastases: Survival, tumor control, and patient outcomes. Int J Radiat Oncol Biol Phys; 2007 Feb 1;67(2):521-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Stereotactic radiosurgery for brainstem metastases: Survival, tumor control, and patient outcomes.
  • PURPOSE: Patients with brainstem metastases have limited treatment options.
  • In this study, we reviewed outcomes after stereotactic radiosurgery (SRS) in the management of patients with brainstem metastases.
  • METHODS AND MATERIALS: Records were reviewed of 22 consecutive patients presenting with brainstem metastases who underwent SRS.
  • Three patients (14%) also underwent whole-brain radiation therapy (WBRT).
  • The median tumor volume was 0.9 mL (range, 0.1-3.3 mL); the median tumor margin dose was 16 Gy (range, 14-23 Gy).
  • Although local tumor control was achieved in all patients with imaging follow-up (n = 19), 5 patients died from development and progression of new brain metastases.
  • CONCLUSIONS: Radiosurgery is safe and provides a high local tumor control rate for patients with small brainstem metastases.
  • [MeSH-major] Brain Stem Neoplasms / radiotherapy. Radiosurgery / methods
  • [MeSH-minor] Adult. Aged. Breast Neoplasms. Female. Humans. Kidney Neoplasms. Lung Neoplasms. Male. Middle Aged. Treatment Outcome

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  • (PMID = 17097830.001).
  • [ISSN] 0360-3016
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
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59. Yu LM, Yang SM, Han DY, Yu LM, Yang WY: [Preliminary study of intraoperative auditory monitoring techniques in acoustic neuroma surgery]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2006 May;41(5):335-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Continuous hearing monitoring of auditory brainstem responses (ABR) and transtympanic electrocochleography (ECochG) was performed during operation.
  • The hearing was preserved in 2 cases, which had class A hearing post operation with tumor size <2 cm.
  • In another case, the waves of I, III could be evoked after the tumor resection with the disappearance of wave V.
  • The CAP amplitudes decreased significantly in 4 cases and even dropped to zero while dissecting the tumor at the lateral end of the internal auditory canal (IAC) or clamping the internal auditory artery (IAA) during operation.
  • In one case, although the cochlear nerve was cut down, the CAP could still be recorded after the tumor resection.
  • However, the CAP amplitudes was dropped to zero while pressurized and pulled cochlea nerve of brainstem lateral and the wave disappeared post-operation in another cases.
  • One of them showed low amplitude of CAP wave when the tumor partially removed.
  • Drilling of the IAC and tumor removal at the lateral end of the IAC were the most critical steps for achieving hearing preservation.
  • [MeSH-minor] Adolescent. Adult. Audiometry, Evoked Response. Evoked Potentials, Auditory, Brain Stem. Female. Humans. Male. Middle Aged. Young Adult

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  • (PMID = 16848284.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] China
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60. Park DM, Zhuang Z, Chen L, Szerlip N, Maric I, Li J, Sohn T, Kim SH, Lubensky IA, Vortmeyer AO, Rodgers GP, Oldfield EH, Lonser RR: von Hippel-Lindau disease-associated hemangioblastomas are derived from embryologic multipotent cells. PLoS Med; 2007 Feb;4(2):e60
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  • BACKGROUND: To determine the origin of the neoplastic cell in central nervous system (CNS) hemangioblastomas in von Hippel-Lindau disease (VHL) and its role in tumor formation and distribution, we characterized and differentiated neoplastic cells from hemangioblastomas removed from VHL patients.
  • Tumor cells from the hemangioblastomas were characterized, grown, and differentiated into multiple lineages.
  • Resected hemangioblastomas were located in the cerebellum (11 tumors), brainstem (five tumors), and spinal cord (15 tumors).
  • Consistent with an embryologically derived hemangioblast, the neoplastic cells demonstrated coexpression of the mesodermal markers brachyury, Flk-1 (vascular endothelial growth factor-2), and stem cell leukemia (Scl).
  • The neoplastic cells also expressed hematopoietic stem cell antigens and receptors including CD133, CD34, c-kit, Scl, erythropoietin, and erythropoietin receptor.
  • These findings may also explain the unique tissue distribution of tumor involvement.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Hemangioblastoma / pathology. Multipotent Stem Cells / pathology. von Hippel-Lindau Disease / complications
  • [MeSH-minor] Adolescent. Adult. Antigens, CD13 / genetics. Blotting, Western. Cell Degranulation. Female. Follow-Up Studies. Gene Expression Regulation, Neoplastic. Humans. Male. Middle Aged. RNA, Neoplasm / genetics. Retrospective Studies. Reverse Transcriptase Polymerase Chain Reaction. Tumor Cells, Cultured


66. Harter PN, Bunz B, Dietz K, Hoffmann K, Meyermann R, Mittelbronn M: Spatio-temporal deleted in colorectal cancer (DCC) and netrin-1 expression in human foetal brain development. Neuropathol Appl Neurobiol; 2010 Dec;36(7):623-35
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spatio-temporal deleted in colorectal cancer (DCC) and netrin-1 expression in human foetal brain development.
  • METHODS: We investigated 22 human foetal brain specimens (12th and 28th week of gestation) for DCC and netrin-1 expression by means of immunohistochemistry, immunofluorescence and confocal laser microscopy.
  • Distinct co-expression was seen in maturing foetal brainstem nuclei, cerebellar external granular layer and the choroid plexus.
  • CONCLUSIONS: We show that DCC and netrin-1 are ubiquitously expressed in the human foetal brain; however, both exhibit a distinct spatio-temporal expression pattern.
  • [MeSH-major] Brain / embryology. Brain Chemistry / physiology. Nerve Growth Factors / biosynthesis. Receptors, Cell Surface / biosynthesis. Tumor Suppressor Proteins / biosynthesis
  • [MeSH-minor] Adult. Brain Stem / metabolism. Cerebellum / metabolism. Cerebral Cortex / metabolism. Choroid Plexus / metabolism. Ependyma / cytology. Ependyma / metabolism. Female. Fetal Development. Fetus / metabolism. Fluorescent Antibody Technique. Humans. Immunohistochemistry. Pregnancy

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  • [Copyright] © 2010 The Authors. Neuropathology and Applied Neurobiology © 2010 British Neuropathological Society.
  • (PMID = 20609112.001).
  • [ISSN] 1365-2990
  • [Journal-full-title] Neuropathology and applied neurobiology
  • [ISO-abbreviation] Neuropathol. Appl. Neurobiol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DCC protein, human; 0 / Nerve Growth Factors; 0 / Receptors, Cell Surface; 0 / Tumor Suppressor Proteins; 158651-98-0 / netrin-1
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67. Hasegawa T, Fujitani S, Katsumata S, Kida Y, Yoshimoto M, Koike J: Stereotactic radiosurgery for vestibular schwannomas: analysis of 317 patients followed more than 5 years. Neurosurgery; 2005 Aug;57(2):257-65; discussion 257-65
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Tumors less than 15 cm3 in volume (10-yr PFS, 96%; P < 0.001) or which did not compress the brainstem and deviate the fourth ventricle (10-yr PFS, 97%; P = 0.008) resulted in significantly better PFS rates.
  • When the tumor was treated with a marginal dose of 13 Gy or less, the hearing preservation rate was 68%, transient facial palsy developed at a rate of 1%, and facial numbness developed at a rate of 2%.
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Longitudinal Studies. Magnetic Resonance Imaging / methods. Male. Middle Aged. Proportional Hazards Models. Retrospective Studies. Time Factors

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  • (PMID = 16094154.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article
  • [Publication-country] United States
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68. Fouladi M, Nicholson HS, Zhou T, Laningham F, Helton KJ, Holmes E, Cohen K, Speights RA, Wright J, Pollack IF, Children's Oncology Group: A phase II study of the farnesyl transferase inhibitor, tipifarnib, in children with recurrent or progressive high-grade glioma, medulloblastoma/primitive neuroectodermal tumor, or brainstem glioma: a Children's Oncology Group study. Cancer; 2007 Dec 1;110(11):2535-41
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  • [Title] A phase II study of the farnesyl transferase inhibitor, tipifarnib, in children with recurrent or progressive high-grade glioma, medulloblastoma/primitive neuroectodermal tumor, or brainstem glioma: a Children's Oncology Group study.
  • BACKGROUND: An open-label Phase II study of tipifarnib was conducted to evaluate its safety and efficacy in children with recurrent or refractory medulloblastoma (MB)/primitive neuroectodermal tumor (PNET), high-grade glioma (HGG), and diffuse intrinsic brainstem glioma (BSG).
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Brain Neoplasms / drug therapy. Brain Stem Neoplasms / drug therapy. Glioma / drug therapy. Medulloblastoma / drug therapy. Quinolones / therapeutic use
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Disease Progression. Female. Humans. Male. Neuroectodermal Tumors / drug therapy. Treatment Outcome


69. Strauss C, Bischoff B, Romstöck J, Rachinger J, Rampp S, Prell J: Hearing preservation in medial vestibular schwannomas. J Neurosurg; 2008 Jul;109(1):70-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: A consecutive series of 31 cases in 30 patients with medial VSs (mean size 31 mm) who underwent surgery between 1997 and 2005 via a suboccipitolateral route was evaluated with respect to pre- and postoperative cochlear nerve function, extent of tumor removal, and radiological findings.
  • Intraoperative monitoring of brainstem auditory evoked potentials was performed in all patients with hearing.
  • Tumor removal was complete in all patients with hearing preservation, except for 2 patients with neurofibromatosis.
  • In 1 patient a recurrent tumor was completely removed 3 years after the initial procedure.
  • Even in large tumors, hearing could be preserved in 37% of cases, since the cochlear nerve in medial schwannomas may not exhibit the adherence to the tumor capsule seen in tumors with comparable size involving the internal auditory canal.
  • [MeSH-minor] Adult. Aged. Cochlear Nerve / physiopathology. Cohort Studies. Facial Nerve / physiopathology. Female. Humans. Male. Middle Aged. Neoplasm Invasiveness. Recovery of Function / physiology. Treatment Outcome

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  • (PMID = 18590434.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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70. Oermann E, Collins BT, Erickson KT, Yu X, Lei S, Suy S, Hanscom HN, Kim J, Park HU, Eldabh A, Kalhorn C, McGrail K, Subramaniam D, Jean WC, Collins SP: CyberKnife enhanced conventionally fractionated chemoradiation for high grade glioma in close proximity to critical structures. J Hematol Oncol; 2010;3:22
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  • METHODS: Between January 2002 and January 2009, 24 patients with good performance status and high-grade gliomas in close proximity to critical structures (i.e. eyes, optic nerves, optic chiasm and brainstem) were treated with the CyberKnife.
  • All patients received conventional radiation therapy following tumor resection, with a median dose of 50 Gy (range: 40 - 50.4 Gy).
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Brain Neoplasms / therapy. Glioma / therapy. Radiosurgery
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Combined Modality Therapy. Dose Fractionation. Female. Humans. Male. Middle Aged. Radiotherapy Dosage. Radiotherapy Planning, Computer-Assisted. Survival Rate. Treatment Outcome

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  • [Cites] Int J Radiat Oncol Biol Phys. 2001 Dec 1;51(5):1313-9 [11728692.001]
  • [Cites] J Neurosurg. 2000 Dec;93 Suppl 3:219-22 [11143252.001]
  • [Cites] Neurosurgery. 2003 Jan;52(1):140-6; discussion 146-7 [12493111.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2003 Apr 1;55(5):1400-8 [12654453.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2004 Mar 1;58(3):721-6 [14967426.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2004 Mar 15;58(4):1147-52 [15001257.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2004 Nov 1;60(3):853-60 [15465203.001]
  • [Cites] Neurosurgery. 2004 Nov;55(5):1138-49 [15509320.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1976 Jul-Aug;1(7-8):627-37 [185169.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1979 Oct;5(10):1725-31 [231022.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1989 Jun;16(6):1405-9 [2542195.001]
  • [Cites] J Natl Cancer Inst. 1993 May 5;85(9):704-10 [8478956.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1998 Jan 1;40(1):51-5 [9422557.001]
  • [Cites] Neurosurgery. 2005 Jun;56(6):1254-61; discussion 1261-3 [15918941.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2006 Mar 1;64(3):892-7 [16458777.001]
  • [Cites] J Clin Oncol. 2006 Jun 20;24(18):2715-22 [16782911.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2006 Aug 1;65(5):1422-8 [16750317.001]
  • [Cites] Radiat Oncol. 2006;1:46 [17173702.001]
  • [Cites] J Clin Oncol. 2007 Sep 10;25(26):4127-36 [17827463.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2008 Jul 1;71(3):926-33 [18514784.001]
  • [Cites] Phys Med Biol. 2008 Sep 7;53(17):4697-718 [18695294.001]
  • [Cites] Lancet Oncol. 2009 May;10(5):459-66 [19269895.001]
  • [Cites] J Hematol Oncol. 2009;2:16 [19341478.001]
  • [Cites] Semin Radiat Oncol. 2009 Jul;19(3):179-86 [19464633.001]
  • [Cites] CA Cancer J Clin. 2009 Jul-Aug;59(4):225-49 [19474385.001]
  • [Cites] Neurosurg Rev. 2009 Oct;32(4):417-24 [19633875.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2010 Mar 1;76(3 Suppl):S20-7 [20171513.001]
  • [Cites] J Clin Oncol. 2002 Mar 15;20(6):1635-42 [11896114.001]
  • (PMID = 20534128.001).
  • [ISSN] 1756-8722
  • [Journal-full-title] Journal of hematology & oncology
  • [ISO-abbreviation] J Hematol Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2891601
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71. Engler H, Doenlen R, Riether C, Engler A, Besedovsky HO, Del Rey A, Pacheco-López G, Schedlowski M: Chemical destruction of brain noradrenergic neurons affects splenic cytokine production. J Neuroimmunol; 2010 Feb 26;219(1-2):75-80
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  • [Title] Chemical destruction of brain noradrenergic neurons affects splenic cytokine production.
  • Intraperitoneal administration of DSP-4 in adult rats induced a substantial reduction of noradrenergic neurons in the locus coeruleus and the A5 cell group.
  • The degeneration of brainstem noradrenergic neurons was accompanied by a significant decrease in the production of interleukin (IL)-1beta, IL-6, and tumor necrosis factor (TNF)-alpha by lipopolysaccharide-stimulated splenocytes.
  • [MeSH-major] Benzylamines / toxicity. Brain / cytology. Cytokines / metabolism. Neurons / drug effects. Neurotoxins / toxicity. Norepinephrine / analogs & derivatives. Spleen / drug effects

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  • [Copyright] Copyright 2009 Elsevier B.V. All rights reserved.
  • (PMID = 20031236.001).
  • [ISSN] 1872-8421
  • [Journal-full-title] Journal of neuroimmunology
  • [ISO-abbreviation] J. Neuroimmunol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antigens, CD3; 0 / Benzylamines; 0 / Cytokines; 0 / Lipopolysaccharides; 0 / Neurotoxins; 499-61-6 / noradrenalone; EC 1.14.16.2 / Tyrosine 3-Monooxygenase; PQ1P7JP5C1 / DSP 4; X4W3ENH1CV / Norepinephrine
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72. Park HY, Kim SH, Son EJ, Lee HK, Lee WS: Intracanalicular facial nerve schwannoma. Otol Neurotol; 2007 Apr;28(3):376-80
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  • INTERVENTIONS: Pure-tone average, auditory brainstem response, caloric test, and temporal magnetic resonance imaging were done in all 11 patients.
  • MAIN OUTCOME MEASURE: Preoperative symptoms, pure-tone average, auditory brainstem response, caloric test, electroneuronography, and magnetic resonance imaging were compared between patients with facial nerve schwannomas and patients with vestibular schwannomas.
  • CONCLUSION: A facial nerve schwannoma may be misdiagnosed as a vestibular schwannoma, especially when the tumor is confined to the internal auditory canal.
  • [MeSH-minor] Adult. Aged. Audiometry, Pure-Tone. Diagnosis, Differential. Ear, Inner. Evoked Potentials, Auditory, Brain Stem / physiology. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neuroma, Acoustic / pathology. Otologic Surgical Procedures. Retrospective Studies

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  • (PMID = 17414044.001).
  • [ISSN] 1531-7129
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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73. Asthagiri AR, Mehta GU, Zach L, Li X, Butman JA, Camphausen KA, Lonser RR: Prospective evaluation of radiosurgery for hemangioblastomas in von Hippel-Lindau disease. Neuro Oncol; 2010 Jan;12(1):80-6
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  • Twenty VHL patients (10 males and 10 females) underwent SRS treatment of 44 CNS hemangioblastomas (39 cerebellar and 5 brainstem).
  • Mean treated tumor volume was 0.5 +/- 0.7 cm(3) (range: 0.01-3.6 cm(3)).
  • Mean prescription dose was 18.9 Gy (range: 12-24 Gy) at the tumor margin.
  • Univariate analysis did not identify variables associated (P > .05) with worse tumor control at last follow-up.

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  • [Cites] Acta Neurochir (Wien). 2000;142(6):641-4; discussion 644-5 [10949438.001]
  • [Cites] Neurosurgery. 2008 Sep;63(3):443-50; discussion 450-1 [18812955.001]
  • [Cites] J Neurosurg. 2003 Jan;98(1):95-105 [12546357.001]
  • [Cites] J Neurosurg. 2003 Jan;98(1):106-16 [12546358.001]
  • [Cites] Lancet. 2003 Jun 14;361(9374):2059-67 [12814730.001]
  • [Cites] J Neurosurg. 2003 Jul;99(1 Suppl):64-9 [12859062.001]
  • [Cites] Nature. 1988 Mar 17;332(6161):268-9 [2894613.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1990 May;18(5):1165-71 [2347723.001]
  • [Cites] Lancet. 1991 May 4;337(8749):1052-4 [1673491.001]
  • [Cites] J Comput Assist Tomogr. 1992 Jul-Aug;16(4):519-28 [1629407.001]
  • [Cites] Science. 1993 May 28;260(5112):1317-20 [8493574.001]
  • [Cites] Surg Neurol. 1993 Nov;40(5):424-8 [8211662.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1996 Jun 1;35(3):493-9 [8655372.001]
  • [Cites] J Neurosurg. 1996 Oct;85(4):591-6 [8814161.001]
  • [Cites] Br J Neurosurg. 1997 Apr;11(2):110-5 [9155996.001]
  • [Cites] Neurosurgery. 1998 Jul;43(1):28-34; discussion 34-5 [9657185.001]
  • [Cites] Stereotact Funct Neurosurg. 1998 Oct;70 Suppl 1:179-86 [9782249.001]
  • [Cites] Am J Med. 1964 Apr;36:595-617 [14142412.001]
  • [Cites] J Neurosurg. 2005 Jan;102 Suppl:97-101 [15662788.001]
  • [Cites] J Neurosurg. 2005 Jan;102 Suppl:171-4 [15662804.001]
  • [Cites] J Neurosurg. 2005 Jan;102 Suppl:225-9 [15662815.001]
  • [Cites] Br J Neurosurg. 2004 Aug;18(4):338-42 [15702831.001]
  • [Cites] Ann Neurol. 2005 Sep;58(3):392-9 [16130092.001]
  • [Cites] J Med Genet. 2006 Apr;43(4):289-94 [16155191.001]
  • [Cites] J Neurosurg. 2006 Aug;105(2):248-55 [17219830.001]
  • [Cites] Acta Neurochir (Wien). 2007 Oct;149(10):1007-13; discussion 1013 [17712513.001]
  • [Cites] J Neurosurg. 2008 Feb;108(2):210-22 [18240914.001]
  • [Cites] JAMA. 2008 Sep 17;300(11):1334-42 [18799446.001]
  • [Cites] J Neurosurg. 2003 Jan;98(1):82-94 [12546356.001]
  • (PMID = 20150370.001).
  • [ISSN] 1523-5866
  • [Journal-full-title] Neuro-oncology
  • [ISO-abbreviation] Neuro-oncology
  • [Language] ENG
  • [Grant] United States / Intramural NIH HHS / /
  • [Publication-type] Clinical Trial; Journal Article; Research Support, N.I.H., Intramural
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2940550
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74. Dwarakanath S, Suri A, Sharma BS, Mehta VS: Intracranial hemangioblastomas: an institutional experience. Neurol India; 2006 Sep;54(3):276-8
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  • The tumor was located in the cerebellar hemispheres, vermian and brainstem regions in 42 (60%) patients, 19 (28%) patients and 8 (12%) patients, respectively.
  • Thirty-three patients underwent CSF diversion procedures prior to surgery on the tumor.
  • Sixty eight patients underwent surgery on the tumor.
  • [MeSH-major] Brain Neoplasms. Hemangioblastoma. Institutional Practice / statistics & numerical data
  • [MeSH-minor] Adult. Female. Follow-Up Studies. Humans. Male. Retrospective Studies. von Hippel-Lindau Disease / etiology

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  • (PMID = 16936388.001).
  • [ISSN] 0028-3886
  • [Journal-full-title] Neurology India
  • [ISO-abbreviation] Neurol India
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] India
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75. Abe M, Tokumaru S, Tabuchi K, Kida Y, Takagi M, Imamura J: Stereotactic radiation therapy with chemotherapy in the management of recurrent medulloblastomas. Pediatr Neurosurg; 2006;42(2):81-8
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  • Five patients were treated with one to two sequential courses of high-dose chemotherapy with peripheral blood stem cell transplantation.
  • The reduction in tumor size after SRT was often remarkable.
  • In contrast, all 8 patients with metastasis had new lesions either in the spinal canal or on the surface of the brain outside the target area of SRT.
  • One patient had brainstem edema after SRT causing bulbar palsy and quadriparesis.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Cerebellar Neoplasms / therapy. Medulloblastoma / therapy. Neoplasm Recurrence, Local / therapy. Radiosurgery / methods
  • [MeSH-minor] Adolescent. Adult. Chemotherapy, Adjuvant. Child. Child, Preschool. Cisplatin / administration & dosage. Dose-Response Relationship, Drug. Etoposide / administration & dosage. Female. Humans. Ifosfamide / administration & dosage. Male. Peripheral Blood Stem Cell Transplantation. Radiotherapy Dosage. Retrospective Studies

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  • [Copyright] Copyright (c) 2006 S. Karger AG, Basel.
  • (PMID = 16465076.001).
  • [ISSN] 1016-2291
  • [Journal-full-title] Pediatric neurosurgery
  • [ISO-abbreviation] Pediatr Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 6PLQ3CP4P3 / Etoposide; Q20Q21Q62J / Cisplatin; UM20QQM95Y / Ifosfamide
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76. Kiyomizu K, Matsuda K, Nakayama M, Tono T, Matsuura K, Kawano H, Toyama K, Komune S: Preservation of the auditory nerve function after translabyrinthine removal of vestibular schwannoma. Auris Nasus Larynx; 2006 Mar;33(1):7-11
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  • After surgery, the electrical stimulation test (EST) or electrically evoked auditory brainstem response (EABR) was performed.
  • The maximum tumor size in the group with a positive response to EST or EABR was significantly smaller than that in the group with a negative response to EST.
  • It seems to be difficult to preserve auditory nerve function in cases where a tumor extends to the fundus of internal auditory canal.
  • CONCLUSION: These results suggest that size of tumor and/or extension of tumor to the fundus might be important factors in preserving the auditory nerve function even if using a TL approach.
  • [MeSH-minor] Adult. Aged. Electric Stimulation. Evoked Potentials, Auditory, Brain Stem. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Postoperative Period. Preoperative Care


77. Torcuator R, Zuniga R, Loutfi R, Mikkelsen T: Bevacizumab and irinotecan treatment for progressive diffuse brainstem glioma: case report. J Neurooncol; 2009 Jul;93(3):409-12
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  • [Title] Bevacizumab and irinotecan treatment for progressive diffuse brainstem glioma: case report.
  • Diffuse brainstem glioma carries a dismal prognosis.
  • In this paper, we report our experience in an adult patient with progressive diffuse brainstem glioma treated with bevacizumab and irinotecan.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Brain Stem Neoplasms / drug therapy. Glioma / drug therapy
  • [MeSH-minor] Adult. Antibodies, Monoclonal / administration & dosage. Antibodies, Monoclonal, Humanized. Bevacizumab. Camptothecin / administration & dosage. Camptothecin / analogs & derivatives. Combined Modality Therapy. Female. Humans. Magnetic Resonance Imaging. Radiotherapy

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  • [CommentIn] J Neurooncol. 2009 Nov;95(2):299-300 [19506812.001]
  • [Cites] J Clin Oncol. 2010 Jun 20;28(18):3069-75 [20479404.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1998 Jan 15;40(2):265-71 [9457808.001]
  • [Cites] Brain. 2001 Dec;124(Pt 12):2528-39 [11701605.001]
  • [Cites] J Neurooncol. 1998 Nov;40(2):171-7 [9892099.001]
  • [Cites] J Clin Oncol. 2007 Oct 20;25(30):4722-9 [17947719.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2003 Apr 1;55(5):1182-5 [12654425.001]
  • [Cites] Arch Neurol. 1999 Apr;56(4):421-5 [10199329.001]
  • [Cites] Pediatr Neurosurg. 1996;24(1):24-34 [8817612.001]
  • [Cites] Childs Nerv Syst. 1998 Apr-May;14(4-5):167-73 [9660117.001]
  • [Cites] Acta Neurochir (Wien). 1999;141(7):721-6; discussion 726-7 [10481783.001]
  • [Cites] Childs Nerv Syst. 1998 Oct;14(10):578-81 [9840382.001]
  • [Cites] Oncology (Williston Park). 2005 Apr;19(4 Suppl 3):7-16 [15934498.001]
  • [Cites] J Neurooncol. 2005 Dec;75(3):253-66 [16195805.001]
  • [Cites] Nat Rev Neurosci. 2007 Aug;8(8):610-22 [17643088.001]
  • [Cites] Neurology. 1998 Oct;51(4):1136-9 [9781543.001]
  • [Cites] Cancer. 1996 May 15;77(10):2150-6 [8640684.001]
  • [Cites] Oncologist. 2004;9(2):197-206 [15047924.001]
  • [Cites] Clin Cancer Res. 2007 Feb 15;13(4):1253-9 [17317837.001]
  • [Cites] Br J Cancer. 2002 Oct 21;87(9):945-9 [12434281.001]
  • [Cites] Cancer Chemother Pharmacol. 1997;39(4):376-9 [9025780.001]
  • [Cites] Pediatr Neurosurg. 1996;24(2):98-102 [8841080.001]
  • [Cites] J Neurooncol. 2008 May;87(3):355-61 [18217208.001]
  • [Cites] Childs Nerv Syst. 1999 Oct;15(10):545-53 [10550585.001]
  • [Cites] Mol Cell Biochem. 2008 May;312(1-2):71-80 [18259841.001]
  • (PMID = 19139822.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 0H43101T0J / irinotecan; 2S9ZZM9Q9V / Bevacizumab; XT3Z54Z28A / Camptothecin
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78. Narayana A, Yamada J, Berry S, Shah P, Hunt M, Gutin PH, Leibel SA: Intensity-modulated radiotherapy in high-grade gliomas: clinical and dosimetric results. Int J Radiat Oncol Biol Phys; 2006 Mar 1;64(3):892-7
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  • A comparative dosimetric analysis revealed that regardless of tumor location, IMRT did not significantly improve target coverage compared with three-dimensional planning.
  • The mean brainstem dose also decreased by 7%.
  • Intensity-modulated radiotherapy delivered with a limited number of beams did not result in an increased dose to the normal brain.
  • [MeSH-major] Brain Neoplasms / radiotherapy. Glioma / radiotherapy. Radiotherapy, Intensity-Modulated
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Brain / radiation effects. Disease Progression. Female. Glioblastoma / radiotherapy. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Oligodendroglioma / radiotherapy. Radiotherapy Dosage. Retrospective Studies

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  • (PMID = 16458777.001).
  • [ISSN] 0360-3016
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
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79. Araneda S, Commin L, Atlagich M, Kitahama K, Parraguez VH, Pequignot JM, Dalmaz Y: VEGF overexpression in the astroglial cells of rat brainstem following ozone exposure. Neurotoxicology; 2008 Nov;29(6):920-7
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  • [Title] VEGF overexpression in the astroglial cells of rat brainstem following ozone exposure.
  • Vascular endothelial growth factor (VEGF) is a factor associated with cellular recovery following brain injury.
  • Adult rats were subjected to 0.5ppm ozone for 3h and then recovered for further 3h.
  • The VEGF up-regulation which persists after ozone exposure may contribute to brain repair and consecutive functional adaptations.
  • [MeSH-minor] Animals. Glial Fibrillary Acidic Protein / metabolism. Interleukin-6 / metabolism. Male. Rats. Rats, Sprague-Dawley. Time Factors. Tumor Necrosis Factor-alpha / metabolism

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  • (PMID = 18848842.001).
  • [ISSN] 0161-813X
  • [Journal-full-title] Neurotoxicology
  • [ISO-abbreviation] Neurotoxicology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein; 0 / Interleukin-6; 0 / Oxidants, Photochemical; 0 / Tumor Necrosis Factor-alpha; 0 / Vascular Endothelial Growth Factor A; 66H7ZZK23N / Ozone
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80. Waldron JS, Tihan T, Parsa AT: Solitary fibrous tumor arising from Cranial Nerve VI in the prepontine cistern: case report and review of a tumor subpopulation mimicking schwannoma. Neurosurgery; 2006 Oct;59(4):E939-40; discussion E940
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  • [Title] Solitary fibrous tumor arising from Cranial Nerve VI in the prepontine cistern: case report and review of a tumor subpopulation mimicking schwannoma.
  • OBJECTIVE: The authors present a report of a solitary fibrous tumor (SFT) arising from the intradural component of the VIth cranial nerve as it travels through the prepontine cistern.
  • Outside imaging revealed a 3.9-cm mass in the prepontine cistern with extension into Meckel's cave and the cavernous sinus, resulting in significant brainstem compression.
  • The patient was then taken to the operating room by a combined neurosurgical and ear, nose, and throat team, where the patient underwent a retrolabyrinthine/subtemporal craniotomy for tumor resection.
  • During resection of the prepontine component, the tumor was identified as originating from the left Cranial Nerve VI as it traversed through the prepontine cistern.
  • Resection of the tumor component involving the cavernous sinus and Meckel's cave was deferred for follow-up treatment with intensity-modulated radiation therapy.
  • [MeSH-minor] Adult. Cerebral Angiography. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Radiotherapy, Adjuvant

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  • (PMID = 17038929.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 26
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81. Kim MS, Pyo SY, Jeong YG, Lee SI, Jung YT, Sim JH: Gamma knife surgery for intracranial cavernous hemangioma. J Neurosurg; 2005 Jan;102 Suppl:102-6
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  • The tumor decreased in size in 29 cases, was unchanged in 12, and increased in size in one.
  • CONCLUSIONS: The authors found that GKS was an effective treatment modality for cavernous hemangiomas, especially for those located within the brainstem, basal ganglia, or deep portions of the brain.
  • [MeSH-major] Brain Neoplasms / surgery. Hemangioma, Cavernous, Central Nervous System / surgery. Radiosurgery / instrumentation
  • [MeSH-minor] Adolescent. Adult. Basal Ganglia / pathology. Basal Ganglia / surgery. Cerebellum / pathology. Cerebellum / surgery. Child. Electroencephalography. Follow-Up Studies. Frontal Lobe / pathology. Frontal Lobe / surgery. Humans. Magnetic Resonance Imaging. Middle Aged. Parietal Lobe / pathology. Parietal Lobe / surgery. Pons / pathology. Pons / surgery. Radiation Dosage. Seizures / diagnosis. Seizures / etiology


82. Caprile T, Salazar K, Astuya A, Cisternas P, Silva-Alvarez C, Montecinos H, Millán C, de Los Angeles García M, Nualart F: The Na+-dependent L-ascorbic acid transporter SVCT2 expressed in brainstem cells, neurons, and neuroblastoma cells is inhibited by flavonoids. J Neurochem; 2009 Feb;108(3):563-77
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  • [Title] The Na+-dependent L-ascorbic acid transporter SVCT2 expressed in brainstem cells, neurons, and neuroblastoma cells is inhibited by flavonoids.
  • As the brain does not synthesize AA, high levels are achieved in this organ by specific uptake mechanisms, which concentrate AA from the bloodstream to the CSF and from the CSF to the intracellular compartment.
  • In the adult brain the expression of SVCT2 was observed in the hippocampus and cortical neurons by in situ hybridization; however, there is no data regarding the expression and distribution of this transporter in the fetal brain.
  • We analyze SVCT2 expression in human and rat developing brain by RT-PCR.
  • Additionally, we study the normal localization of SVCT2 in rat fetal brain by immunohistochemistry and in situ hybridization demonstrating that SVCT2 is highly expressed in the ventricular and subventricular area of the rat brain.
  • SVCT2 expression and function was also confirmed in neurons isolated from brain cortex and cerebellum.
  • Our data demonstrates that brain cortex and cerebellar stem cells, neurons and neuroblastoma cells express SVCT2.
  • [MeSH-major] Brain Neoplasms / metabolism. Brain Stem / metabolism. Flavonoids / pharmacology. Neuroblastoma / metabolism. Neurons / metabolism. Organic Anion Transporters, Sodium-Dependent / antagonists & inhibitors. Organic Anion Transporters, Sodium-Dependent / biosynthesis. Sodium / physiology. Symporters / antagonists & inhibitors. Symporters / biosynthesis
  • [MeSH-minor] Animals. Ascorbic Acid / metabolism. Blotting, Western. Cell Line, Tumor. Cerebellum / cytology. Cerebellum / drug effects. Cerebellum / metabolism. Cerebral Cortex / cytology. Cerebral Cortex / drug effects. Cerebral Cortex / metabolism. DNA, Complementary / biosynthesis. DNA, Complementary / genetics. Female. Humans. Immunohistochemistry. In Situ Hybridization. Kinetics. Mice. Pregnancy. Rats. Rats, Sprague-Dawley. Reverse Transcriptase Polymerase Chain Reaction. Sodium-Coupled Vitamin C Transporters

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  • (PMID = 19054284.001).
  • [ISSN] 1471-4159
  • [Journal-full-title] Journal of neurochemistry
  • [ISO-abbreviation] J. Neurochem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DNA, Complementary; 0 / Flavonoids; 0 / Organic Anion Transporters, Sodium-Dependent; 0 / SLC23A1 protein, human; 0 / SLC23A2 protein, human; 0 / Slc23a1 protein, mouse; 0 / Slc23a1 protein, rat; 0 / Slc23a2 protein, mouse; 0 / Slc23a2 protein, rat; 0 / Sodium-Coupled Vitamin C Transporters; 0 / Symporters; 9NEZ333N27 / Sodium; PQ6CK8PD0R / Ascorbic Acid
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83. Sahu RN, Mehrotra N, Tyagi I, Banerji D, Jain VK, Behari S: Management strategies for bilateral vestibular schwannomas. J Clin Neurosci; 2007 Aug;14(8):715-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • AIMS: To highlight the differences in clinical presentations and surgical results of bilateral VS compared to unilateral VS; and, to propose a management strategy for these tumors with reference to tumor size, extent of growth and the presence or absence of hearing impairment.
  • Assessment of VIIth and VIIIth cranial nerve function, tumor size, volume and extent of growth was performed in all patients.
  • The management strategy was based on Samii's classification of tumor extent.
  • Giant tumors were present in seven (43.7%) patients; large tumors in eight (50%) and a medium-sized tumor in one (6.3%).
  • Total tumor resection was achieved in 13 patients and subtotal resection in two.
  • On the contralateral side, one large tumor required total excision.
  • One medium sized tumor underwent sub-capsular excision in an attempt to preserve hearing.
  • CONCLUSIONS: Patients with bilateral schwannomas are younger, have larger lesions, poorer preoperative hearing and are more likely to lose either auditory and/or facial nerve function during attempted total resection of the tumor.
  • Classifying the tumors into two groups by extent, that is, tumors extending to the cerebellopontine angle cistern (T1-T3a) and, tumors extending to or compressing the brainstem (T3b to T4b), allows the surgical strategy to be defined.
  • [MeSH-minor] Adult. Cranial Nerves / physiopathology. Female. Hearing Disorders / etiology. Humans. Intracranial Pressure / physiology. Longitudinal Studies. Magnetic Resonance Imaging / methods. Male. Retrospective Studies. Tomography, X-Ray Computed / methods

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  • (PMID = 17577524.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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84. Demetriades AK, Saunders N, Rose P, Fisher C, Rowe J, Tranter R, Hardwidge C: Malignant transformation of acoustic neuroma/vestibular schwannoma 10 years after gamma knife stereotactic radiosurgery. Skull Base; 2010 Sep;20(5):381-7
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  • We present the case of a young adult who had combined operative/Gamma knife treatment for a benign vestibular schwannoma, followed by further surgery 2 years later.
  • He represented 10 years after original diagnosis with facial numbness and ataxia, MRI showing gross tumor recurrence.
  • After radical resection, histology showed malignant transformation to a malignant peripheral nerve sheath tumor.
  • Within 3 months there was rapid, aggressive recurrence with brainstem compression, requiring further surgery for brainstem decompression.
  • While awaiting radiotherapy the tumor recurred again, the patient succumbing.
  • The tumor biology of vestibular schwannomata as well as the radiobiology in the context of malignant transformation is discussed.

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  • [Cites] Nucleic Acids Res. 1983 Oct 25;11(20):7191-203 [6634412.001]
  • (PMID = 21359005.001).
  • [ISSN] 1532-0065
  • [Journal-full-title] Skull base : official journal of North American Skull Base Society ... [et al.]
  • [ISO-abbreviation] Skull Base
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3023338
  • [Keywords] NOTNLM ; Gamma knife radiosurgery / Vestibular schwannoma / acoustic neuroma / anaplastic sarcoma / malignant peripheral nerve sheath tumor (MPNST) / malignant transformation / radiotherapy
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85. Yang LS, Wang YQ, Huang FP: [Correlation between the prognosis of medulloblastoma and relevant clinical factors: analysis of 73 cases]. Zhonghua Yi Xue Za Zhi; 2007 May 22;87(19):1322-5
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  • The correlation between the prognosis and the clinical factors, such and sex, age, tumor location, extent of tumor resection, brainstem invasion, radiotherapy, chemotherapy, ventriculoperitoneal shunt and glial differentiation was analyzed.
  • Those undergoing whole brain/posterior fossa plus spinal axis radiotherapy showed a better prognosis than those undergoing whole brain/posterior fossa radiotherapy.
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Combined Modality Therapy. Female. Follow-Up Studies. Humans. Kaplan-Meier Estimate. Male. Prognosis. Retrospective Studies. Survival Rate

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  • (PMID = 17727776.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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86. Shih C, Tseng FY, Yeh TH, Hsu CJ, Chen YS: Ipsilateral and contralateral acoustic brainstem response abnormalities in patients with vestibular schwannoma. Otolaryngol Head Neck Surg; 2009 Dec;141(6):695-700
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  • [Title] Ipsilateral and contralateral acoustic brainstem response abnormalities in patients with vestibular schwannoma.
  • OBJECTIVE: To analyze auditory brainstem response (ABR) data in patients with vestibular schwannomas (VS) in an effort to identify correlations between abnormal ABR parameters and tumor size.
  • Average VS tumor size was 2.48 +/- 1.31 cm.
  • Tumor size was positively correlated with pure-tone average (P = 0.0106) and with the total number of bilateral abnormal ABR parameters (P = 0.004).
  • CONCLUSIONS: We identified a correlation between ABR parameters and VS tumor size.
  • An ipsilateral ILD-I-V greater than 0.2 ms was sensitive for detecting vs. Abnormal contralateral wave V and interpeak III-V latency indicated a tumor size potentially larger than 2 cm.
  • [MeSH-major] Evoked Potentials, Auditory, Brain Stem / physiology. Neuroma, Acoustic / physiopathology
  • [MeSH-minor] Adolescent. Adult. Aged. Audiometry, Pure-Tone. Cross-Sectional Studies. Female. Humans. Linear Models. Male. Middle Aged. Retrospective Studies. Vestibular Function Tests

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  • (PMID = 19932840.001).
  • [ISSN] 1097-6817
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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87. Liu Q, Liu R, Kashyap MV, Agarwal R, Shi X, Wang CC, Yang SH: Brainstem glioma progression in juvenile and adult rats. J Neurosurg; 2008 Nov;109(5):849-55
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  • [Title] Brainstem glioma progression in juvenile and adult rats.
  • OBJECT: Brainstem gliomas are common in children and have the worst prognosis of any brain tumor in this age group.
  • On the other hand, brainstem gliomas are rare in adults, and the authors of some clinical studies have suggested that this lesion behaves differently in adults than in children.
  • In the present study, the authors test an orthotopic C6 brainstem glioma model in juvenile and adult rats, and investigate the biological behavior of this lesion in the 2 age groups.
  • METHODS: The C6 glioma cells were stereotactically implanted into the pons of juvenile or adult male rats.
  • Tumor proliferation and the number of apoptotic cells in brainstem gliomas of young and adult rats were determined by immunohistochemical staining with Ki 67 and terminal deoxynucleotidyl transferase 2'-deoxyuridine 5'-triphosphate-mediated nick-end labeling assay.
  • RESULTS: Striking differences in the onset of neurological signs, duration of symptoms, survival time, tumor growth pattern, tumor proliferation, and number of apoptotic cells were found between the gliomas in the 2 groups of rats.
  • The lesions were relatively focal in adult rats but more diffuse in young rats.
  • Furthermore, brainstem gliomas in adult rats were less proliferative and had more apoptotic cells than those in young rats.
  • CONCLUSIONS: The authors found that the C6 brainstem glioma model in young and adult rats closely imitates the course of brainstem glioma in humans both in neurological findings and histopathological characteristics.
  • Their findings also suggest that the different growth pattern and invasiveness of these lesions in children compared with that in adults could be due to different cellular environments in the 2 age groups, and warrants further investigation into the difference in the host response to brainstem gliomas in children and adults.
  • [MeSH-major] Brain Stem Neoplasms / pathology. Glioma / pathology
  • [MeSH-minor] Age Factors. Animals. Apoptosis. Cell Line, Tumor. Cell Proliferation. Disease Models, Animal. Disease Progression. Kaplan-Meier Estimate. Male. Neoplasm Transplantation / pathology. Rats. Rats, Sprague-Dawley

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  • [Cites] Acta Neurochir (Wien). 1985;76(1-2):12-7 [4003123.001]
  • [Cites] Oncologist. 2004;9(2):197-206 [15047924.001]
  • [Cites] J Neurosurg. 1987 Oct;67(4):483-7 [3309202.001]
  • [Cites] J Neurooncol. 1988 Dec;6(4):309-17 [3221258.001]
  • [Cites] Neurosurg Clin N Am. 1990 Jan;1(1):111-21 [2135963.001]
  • [Cites] J Neurotrauma. 1994 Apr;11(2):187-96 [7932797.001]
  • [Cites] J Neurooncol. 1998 Jan;36(1):91-102 [9525831.001]
  • [Cites] Hum Gene Ther. 1999 Jan 1;10(1):95-101 [10022534.001]
  • [Cites] Arch Dis Child. 1999 Jun;80(6):558-64 [10332008.001]
  • [Cites] Cancer. 1999 Sep 15;86(6):1064-9 [10491535.001]
  • [Cites] Cancer. 2005 Jan 1;103(1):133-9 [15565574.001]
  • [Cites] J Neurooncol. 2004 Nov;70(2):217-28 [15674479.001]
  • [Cites] Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2005 Feb;27(1):7-12 [15782484.001]
  • [Cites] Childs Nerv Syst. 2005 May;21(5):399-403 [15702357.001]
  • [Cites] Neurosurg Focus. 2005 Jun 15;18(6A):E11 [16048287.001]
  • [Cites] J Neurosci Res. 2005 Aug 1;81(3):447-55 [15959903.001]
  • [Cites] Br J Neurosurg. 2005 Apr;19(2):128-36 [16120515.001]
  • [Cites] J Neurooncol. 2005 Dec;75(3):253-66 [16195805.001]
  • [Cites] Lancet Oncol. 2006 Mar;7(3):241-8 [16510333.001]
  • [Cites] Cancer. 2006 Mar 15;106(6):1364-71 [16463390.001]
  • [Cites] J Clin Neurosci. 2006 May;13(4):431-7 [16678721.001]
  • [Cites] Cancer Sci. 2006 Jun;97(6):546-53 [16734735.001]
  • [Cites] Childs Nerv Syst. 2006 Sep;22(9):1127-35 [16568342.001]
  • [Cites] J Neurooncol. 2006 Sep;79(3):281-7 [16598416.001]
  • [Cites] Childs Nerv Syst. 2006 Dec;22(12):1519-25 [17021732.001]
  • [Cites] Pediatr Neurosurg. 2007;43(3):192-201 [17409788.001]
  • [Cites] Int J Biochem Cell Biol. 2004 Jun;36(6):1046-69 [15094120.001]
  • [Cites] J Cell Physiol. 2000 Mar;182(3):311-22 [10653597.001]
  • [Cites] J Neurooncol. 2000;46(3):193-203 [10902851.001]
  • [Cites] Neurosurgery. 2000 Oct;47(4):993-9; discussion 999-1000 [11014444.001]
  • [Cites] Cancer. 2000 Oct 1;89(7):1569-76 [11013373.001]
  • [Cites] Neurosurgery. 2001 Mar;48(3):616-24; discussion 624-5 [11270553.001]
  • [Cites] Pediatr Neurosurg. 2001 Apr;34(4):206-14 [11359114.001]
  • [Cites] Brain. 2001 Dec;124(Pt 12):2528-39 [11701605.001]
  • [Cites] J Neurooncol. 2001 Jul;53(3):275-87 [11718260.001]
  • [Cites] Curr Opin Neurol. 2001 Dec;14(6):711-5 [11723378.001]
  • [Cites] Vet Pathol. 2002 May;39(3):293-9 [12014493.001]
  • [Cites] Cell Tissue Res. 2002 Dec;310(3):257-70 [12457224.001]
  • [Cites] Childs Nerv Syst. 2004 Mar;20(3):143-53 [14669023.001]
  • [Cites] J Neurosurg. 1986 Jan;64(1):11-5 [3941334.001]
  • (PMID = 18976074.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Grant] United States / NINDS NIH HHS / NS / R01 NS054651; United States / NINDS NIH HHS / NS / R01 NS054651-01A2; United States / NINDS NIH HHS / NS / R01 NS054687; United States / NINDS NIH HHS / NS / R01 NS054687-01A2
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS75237; NLM/ PMC2693119
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88. Finkenzeller T, Fellner FA, Trenkler J, Schreyer A, Fellner C: Capillary telangiectasias of the pons. Does diffusion-weighted MR increase diagnostic accuracy? Eur J Radiol; 2010 Jun;74(3):e112-6
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  • BACKGROUND AND PURPOSE: Capillary telangiectasias are benign lesions of the brainstem which are sometimes difficult to distinguish from other lesions in standard MRI.
  • METHODS: 148 MR examinations of patients with pontine lesions were evaluated retrospectively and revealed capillary telangiectasia (n=18), presumed microvascular disease (n=20), encephalitis disseminata (n=21), pontine myelinolysis (n=16), tumor (n=20), acute infarction (n=20), subacute infarction (n=13) and chronic infarction (n=20).
  • Hypointense signal on DWI was very rare for the remaining lesions: only 1 pontine myelinolysis, 1 tumor, 4 subacute infarctions, and 19 chronic infarctions also revealed low signal intensity on DWI.
  • The combination of high signal intensity on T1-weighted post-contrast images and low signal intensity on DWI was found for all capillary telangiectasias, but only for 1/20 tumor and for 4/13 subacute infarctions.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Female. Humans. Male. Middle Aged. Reproducibility of Results. Sensitivity and Specificity. Young Adult

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  • [Copyright] Copyright (c) 2009 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 19477096.001).
  • [ISSN] 1872-7727
  • [Journal-full-title] European journal of radiology
  • [ISO-abbreviation] Eur J Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
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89. Kakigi A, Nakatani H, Takeda T: Electrocochleographic and pure-tone audiometric findings in contralateral ear of unilateral acoustic neurinoma. ORL J Otorhinolaryngol Relat Spec; 2010;71 Suppl 1:78-84
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  • OBJECTIVE: Auditory disorders of the contralateral ear in patients with unilateral acoustic neurinoma have previously been reported using the auditory brainstem response.
  • In the present study, we reported ECoG and pure-tone audiometric results of the contralateral ears in cases of unilateral acoustic neurinoma and the relationship between ECoG findings and tumor size was discussed.
  • METHODS: ECoG and pure-tone audiometry were performed for the contralateral ears in 27 cases of unilateral acoustic neurinoma, and the relationships between tumor size and contralateral ECoG findings and between pure-tone threshold and ECoG findings were investigated.
  • The tumor size was assessed by magnetic resonance imaging.
  • There was no correlation between the incidences of abnormal -SP/AP ratio and tumor size.
  • [MeSH-minor] Adult. Aged. Analysis of Variance. Chi-Square Distribution. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged

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  • (PMID = 20185954.001).
  • [ISSN] 1423-0275
  • [Journal-full-title] ORL; journal for oto-rhino-laryngology and its related specialties
  • [ISO-abbreviation] ORL J. Otorhinolaryngol. Relat. Spec.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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90. Rorke-Adams LB, Portnoy H: Long-term survival of an infant with gliomatosis cerebelli. J Neurosurg Pediatr; 2008 Nov;2(5):346-50
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  • Gliomatosis cerebri is an uncommon but well-established central nervous system neoplasm that occurs primarily in adults.
  • Although the neoplastic process typically arises in the cerebrum, it often spreads to brainstem, cerebellum, or even the spinal cord.
  • In this report the authors document the surgical treatment of a 13-month-old boy whose tumor arose in the cerebellum and over time extended to the thalamus where its growth halted at age 3 years and 10 months.
  • [MeSH-minor] Adult. Disease-Free Survival. Humans. Infant. Male. Neoplasm Invasiveness. Treatment Outcome

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  • (PMID = 18976105.001).
  • [ISSN] 1933-0707
  • [Journal-full-title] Journal of neurosurgery. Pediatrics
  • [ISO-abbreviation] J Neurosurg Pediatr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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91. Ushio M, Iwasaki S, Chihara Y, Kawahara N, Morita A, Saito N, Murofushi T: Is the nerve origin of the vestibular schwannoma correlated with vestibular evoked myogenic potential, caloric test, and auditory brainstem response? Acta Otolaryngol; 2009 Oct;129(10):1095-100
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  • [Title] Is the nerve origin of the vestibular schwannoma correlated with vestibular evoked myogenic potential, caloric test, and auditory brainstem response?
  • CONCLUSIONS: The results of the caloric test, vestibular evoked myogenic potential (VEMP), and auditory brainstem response (ABR) in patients with vestibular schwannoma (VS) did not show clear correlation with the nerve origin of the tumor but with tumor size.
  • When we focused on patients with VS within the internal acoustic canal (IAC), neither the nerve origin of the tumor nor the tumor size showed clear correlation with the results of these tests.
  • Tumor size was measured with preoperative MRI.
  • RESULTS: The nerve origin of the tumor was identified in 63 of the 109 patients.
  • Mean tumor size in patients showing abnormal responses was larger than that in patients showing normal responses on each test.
  • [MeSH-minor] Adult. Aged. Caloric Tests. Evoked Potentials, Auditory, Brain Stem. Humans. Middle Aged. Vestibular Evoked Myogenic Potentials. Vestibular Nerve / pathology. Vestibular Nerve / physiopathology. Young Adult

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  • (PMID = 19034733.001).
  • [ISSN] 1651-2251
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
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92. Jagannathan J, Lonser RR, Smith R, DeVroom HL, Oldfield EH: Surgical management of cerebellar hemangioblastomas in patients with von Hippel-Lindau disease. J Neurosurg; 2008 Feb;108(2):210-22
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  • Preoperative hydrocephalus resolved after tumor removal in 33 cases (94%) and did not require cerebrospinal fluid diversion.
  • Cerebrospinal fluid diversion is rarely necessary after complete tumor removal in patients with preoperative hydrocephalus.
  • Cerebellar hemangioblastomas are preferentially distributed in the posterior half of the cerebellum, as they are in the brainstem and spinal cord.
  • Tumor recurrence is avoided by meticulous extracapsular resection.
  • [MeSH-minor] Adult. Ataxia / physiopathology. Brain Edema / physiopathology. Cerebellar Ataxia / physiopathology. Cranial Irradiation. Cysts / physiopathology. Dissection / methods. Electrocoagulation / methods. Female. Follow-Up Studies. Headache / physiopathology. Humans. Hydrocephalus / physiopathology. Male. Microdissection / methods. Postoperative Complications. Radiosurgery. Radiotherapy, Adjuvant. Retrospective Studies. Treatment Outcome

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  • (PMID = 18240914.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / /
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Intramural
  • [Publication-country] United States
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93. Pichierri A, D'Avella E, Ruggeri A, Tschabitscher M, Delfini R: Endoscopic assistance in the epidural subtemporal approach and Kawase approach: anatomic study. Neurosurgery; 2010 Sep;67(3 Suppl Operative):ons29-37; discussion ons37
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  • METHODS: Twelve epidural subtemporal approaches were performed on 6 adult cadaveric heads.
  • Surgical freedom was limited by the brainstem and the depth of the posterior cranial fossa.
  • CONCLUSION: The endoscope-assisted subtemporal approach can be useful in visualizing tumor in the posterior fossa.
  • It can help the surgeon in planning further surgical steps through consideration of the size, extension, and adherence of the tumor to surrounding structures.

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  • (PMID = 20679951.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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94. Ganigi PM, Santosh V, Anandh B, Chandramouli BA, Sastry Kolluri VR: Expression of p53, EGFR, pRb and bcl-2 proteins in pediatric glioblastoma multiforme: a study of 54 patients. Pediatr Neurosurg; 2005 Nov-Dec;41(6):292-9
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  • Pediatric glioblastoma multiforme (GBM) tumors, which have been established as 'de novo' neoplasms, are known to differ from their adult counterparts in terms of biology, genetics and ultimately survival of patients.
  • In order to evaluate the utility of markers of tumor biology for refining prognostic assessment, we retrospectively analyzed 54 pediatric GBMs (age range 9 months to 15 years) occurring at different anatomical sites in the brain, operated at our institute between 1995 and 2001.
  • The expression of p53, epidermal growth factor receptor (EGFR), bcl-2 and retinoblastoma proteins (pRb) was analyzed by immunohistochemistry and the results were compared with the clinical profile, MIB-1 labeling index (LI) and patient survival. p53 immunoreactivity was noted in 53.7% of cases, predominantly in thalamic (75%) and cerebral lobar (62.2%), followed by brainstem tumors (30%).
  • [MeSH-major] Brain Neoplasms / metabolism. Glioblastoma / metabolism. Proto-Oncogene Proteins c-bcl-2 / metabolism. Receptor, Epidermal Growth Factor / metabolism. Retinoblastoma Protein / metabolism. Tumor Suppressor Protein p53 / metabolism
  • [MeSH-minor] Adolescent. Antibodies, Antinuclear / analysis. Antibodies, Monoclonal / analysis. Biomarkers, Tumor / metabolism. Child. Child, Preschool. Female. Humans. Immunohistochemistry. Infant. Ki-67 Antigen / immunology. Male. Neoplasm Recurrence, Local / metabolism. Prognosis. Retrospective Studies


95. Colletti L, Zoccante L: Nonverbal cognitive abilities and auditory performance in children fitted with auditory brainstem implants: preliminary report. Laryngoscope; 2008 Aug;118(8):1443-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nonverbal cognitive abilities and auditory performance in children fitted with auditory brainstem implants: preliminary report.
  • OBJECTIVES/HYPOTHESIS: Auditory brainstem implants (ABIs) can provide excellent open set speech recognition in adults without auditory tumors.
  • From 2000 to 2006, 17 children aged 14 months to 16 years received an ABI for different tumor and nontumor diseases in our department in Verona, and nine children were operated in other countries.
  • Intraoperative and postoperative electrically evoked auditory brainstem responses were performed in all children.
  • [MeSH-major] Auditory Brain Stem Implants. Cognition Disorders / rehabilitation. Deafness / rehabilitation. Nonverbal Communication
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Comprehension. Humans. Infant. Middle Aged. Treatment Outcome

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  • (PMID = 18496153.001).
  • [ISSN] 1531-4995
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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96. Hasegawa T, Kida Y, Yoshimoto M, Koike J: Trigeminal schwannomas: results of gamma knife surgery in 37 cases. J Neurosurg; 2007 Jan;106(1):18-23
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The authors evaluated tumor control and functional outcomes in patients who underwent GKS for trigeminal schwannomas to clarify the efficacy of this treatment.
  • The mean tumor volume in these patients was 10 cm3.
  • The mean maximum radiation dose directed to the tumor was 27.9 Gy and the mean dose directed to the tumor margin was 14.2 Gy.
  • In four patients (11%) there was complete tumor remission; in 20 (54%) there was partial tumor remission; in eight (22%) the disease remained stable; and in five (14%) the tumor enlarged or uncontrollable facial pain developed with radiation-induced edema requiring resection.
  • The actuarial 5- and 10-year tumor control rates were both 84%.
  • With respect to functional outcomes, 40% of patients noted an improvement in their symptoms, and one patient experienced new symptoms despite good tumor control.
  • Large tumors that compress the brainstem and cause deviation of the fourth ventricle should first be removed surgically and any remnant should be treated by GKS.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Facial Pain / etiology. Facial Pain / prevention & control. Female. Follow-Up Studies. Humans. Hypesthesia / etiology. Hypesthesia / prevention & control. Male. Middle Aged. Retrospective Studies. Treatment Outcome

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  • (PMID = 17236483.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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97. Zaouche S, Ionescu E, Dubreuil C, Ferber-Viart C: Pre- and intraoperative predictive factors of facial palsy in vestibular schwannoma surgery. Acta Otolaryngol; 2005 Apr;125(4):363-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Quantitative parameters: age; duration of clinical symptoms; pure-tone audiometry (PTA) results; speech reception threshold; speech discrimination score; auditory brainstem response (ABR) results; and transient-evoked otoacoustic emission amplitude.
  • Qualitative parameters: gender; side of the tumor; angle between the tumor and the internal auditory canal (VS/IAC angle) < or = or > 30 degrees; MRI aspect (n = 69); surgical approach; ease of the surgical procedure, the use or non-use of laser dissection; and the histological Antoni's type of the tumor.
  • [MeSH-minor] Adult. Aged. Audiometry, Pure-Tone. Brain Stem / physiopathology. Evoked Potentials, Auditory, Brain Stem / physiology. Facial Nerve / physiopathology. Female. Humans. Laser Therapy. Male. Middle Aged. Otoacoustic Emissions, Spontaneous / physiology. Predictive Value of Tests. Preoperative Care. Reference Values. Retrospective Studies. Risk Assessment. Speech Reception Threshold Test


98. Bernat I, Grayeli AB, Esquia G, Zhang Z, Kalamarides M, Sterkers O: Intraoperative electromyography and surgical observations as predictive factors of facial nerve outcome in vestibular schwannoma surgery. Otol Neurotol; 2010 Feb;31(2):306-12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Intraoperative direct facial nerve stimulation at the brainstem (proximal pre site) before resection and at the brainstem (proximal post and distal sites, respectively) and internal acoustic meatus after resection were performed.
  • Poor facial nerve outcomes were observed for large tumor with a facial nerve superior to the tumor with a strong adhesion to the nerve.
  • With a stimulation threshold at proximal site after proximal site tumor resection at less than or equal to 0.04 mA, a good facial function was observed in 77% at Day 8.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Brain Stem / physiology. Electric Stimulation. Electromyography. Facial Nerve / physiology. Female. Humans. Male. Middle Aged. Monitoring, Intraoperative. Neural Conduction / physiology. Predictive Value of Tests. Young Adult

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  • (PMID = 19816232.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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99. Colletti V, Shannon RV: Open set speech perception with auditory brainstem implant? Laryngoscope; 2005 Nov;115(11):1974-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Open set speech perception with auditory brainstem implant?
  • OBJECTIVE: Only a small percentage of auditory brainstem implant (ABI) recipients treated for neurofibromatosis type 2 (NF2) have proved capable of identifying words using only the sound from the ABI.
  • In the present study, a series of psychophysical tests were administered to determine the cause of the difference in performance between tumor (T) and nontumor (NT) ABI patients.
  • In NF2 patients, the tumor and surgery may selectively damage this pathway, resulting in poor speech recognition with prosthetic stimulation.
  • [MeSH-major] Auditory Brain Stem Implantation / instrumentation. Auditory Brain Stem Implants. Hearing Loss, Central / rehabilitation. Speech Perception / physiology. Vestibulocochlear Nerve Diseases / rehabilitation
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Evoked Potentials, Auditory, Brain Stem / physiology. Female. Follow-Up Studies. Humans. Infant. Male. Middle Aged. Retrospective Studies. Treatment Outcome

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  • (PMID = 16319608.001).
  • [ISSN] 0023-852X
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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100. Ueoka DI, Nogueira J, Campos JC, Maranhão Filho P, Ferman S, Lima MA: Brainstem gliomas--retrospective analysis of 86 patients. J Neurol Sci; 2009 Jun 15;281(1-2):20-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Brainstem gliomas--retrospective analysis of 86 patients.
  • Brainstem gliomas constitute 10% of brain tumors in children and less than 2% in adults.
  • Since therapeutic options are limited and brainstem gliomas are associated with a high morbidity and mortality, we sought to analyze the prognostic factors associated with a better outcome.
  • We reviewed the records of 86 patients with brainstem gliomas treated between 1996 and 2006.
  • Of 86 patients with brainstem gliomas, 55.8% were females.
  • A short duration of symptoms, which may imply a more aggressive tumor, was associated with a worst prognosis in patients with brainstem gliomas.
  • [MeSH-major] Brain Stem Neoplasms / diagnosis. Glioma / diagnosis
  • [MeSH-minor] Adolescent. Adult. Age of Onset. Brain Stem / pathology. Child. Child, Preschool. Disease Progression. Female. Humans. Infant. Kaplan-Meier Estimate. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Staging. Prognosis. Retrospective Studies. Treatment Outcome. Young Adult

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  • (PMID = 19345380.001).
  • [ISSN] 1878-5883
  • [Journal-full-title] Journal of the neurological sciences
  • [ISO-abbreviation] J. Neurol. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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