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Items 1 to 100 of about 618
1. Arrese T, González P, Ramos A, Ruiz J, Lobato RD: [Idiopathic hypertrophic pachymeningitis of the cavernous sinus mimicking meningioma with complete occlusion of the carotid artery]. Neurocirugia (Astur); 2005 Feb;16(1):63-6
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  • [Title] [Idiopathic hypertrophic pachymeningitis of the cavernous sinus mimicking meningioma with complete occlusion of the carotid artery].
  • [Transliterated title] Paquimeningitis crónica hipertrófica del seno cavernoso simulando meningioma con oclusión completa de la arteria carótida.
  • We present the case of a patient with IHPM who was diagnosed of meningioma and showed a complete occlusion of the intracavernous carotid artery.
  • This 42 years old woman was sent to our hospital to be treated radiosurgicaly with the diagnosis of meningioma.
  • The differential diagnosis between meningioma and IHPM may be complex because of the similarities in image findings and the temporal resistance to corticosteroids shown by IHPM, thus we emphasize the usefulness of the SPECT to differentiate between inflammation and tumor in this clinical setting.
  • [MeSH-major] Cavernous Sinus / metabolism. Cavernous Sinus / pathology. Meningeal Neoplasms / diagnosis. Meningioma / diagnosis. Meningitis / diagnosis
  • [MeSH-minor] Adult. Anti-Inflammatory Agents / therapeutic use. Brain / pathology. Brain / radionuclide imaging. Carotid Stenosis / diagnosis. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Tomography, Emission-Computed, Single-Photon

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  • (PMID = 15756414.001).
  • [ISSN] 1130-1473
  • [Journal-full-title] Neurocirugía (Asturias, Spain)
  • [ISO-abbreviation] Neurocirugia (Astur)
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents
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2. Loh JK, Hwang SL, Tsai KB, Kwan AL, Howng SL: Sphenoid ridge lymphoplasmacyte-rich meningioma. J Formos Med Assoc; 2006 Jul;105(7):594-8
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  • [Title] Sphenoid ridge lymphoplasmacyte-rich meningioma.
  • There are numerous histologic variants of meningioma.
  • We report a 22-year-old woman with lymphoplasmacyte-rich meningioma who initially presented with dizziness and progressive headache.
  • Histologic examination revealed a meningioma with massive infiltrates of plasma cells and lymphocytes.
  • Brain computed tomography on the 6th postoperative day revealed total removal of the tumor with marked reduction of brain edema.

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  • (PMID = 16877241.001).
  • [ISSN] 0929-6646
  • [Journal-full-title] Journal of the Formosan Medical Association = Taiwan yi zhi
  • [ISO-abbreviation] J. Formos. Med. Assoc.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Singapore
  • [Number-of-references] 19
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3. Chamberlain MC, Glantz MJ: Cerebrospinal fluid-disseminated meningioma. Cancer; 2005 Apr 1;103(7):1427-30
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  • [Title] Cerebrospinal fluid-disseminated meningioma.
  • BACKGROUND: Intracranial meningiomas are common and comprise 20% of all primary brain tumors.
  • CONCLUSIONS: The treatment of CSF-disseminated meningioma, although feasible and comparatively nontoxic, was associated with modest outcomes despite combined systemic and intraventricular chemotherapy.
  • [MeSH-major] Meningioma / secondary
  • [MeSH-minor] Adult. Aged. Antineoplastic Agents / therapeutic use. Brain Neoplasms / pathology. Brain Neoplasms / secondary. Central Nervous System Neoplasms / secondary. Cerebrospinal Fluid / cytology. Female. Humans. Lung Neoplasms / secondary. Lymphatic Metastasis. Male. Middle Aged. Skin Neoplasms / secondary. Spinal Cord Neoplasms / secondary

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  • [Copyright] Copyright 2005 American Cancer Society.
  • (PMID = 15690330.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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4. Khong SY, Leach J, Greenwood C: Meningioma mimicking puerperal psychosis. Obstet Gynecol; 2007 Feb;109(2 Pt2):515-6
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  • [Title] Meningioma mimicking puerperal psychosis.
  • BACKGROUND: Meningiomas are slow-growing benign brain tumors.
  • Meningioma was diagnosed by computed tomography and treated successfully with steroids, anticonvulsant, and craniotomy.
  • Neuroimaging should be performed in the presence of any neurologic abnormality to exclude intracranial lesions such as meningioma.
  • [MeSH-major] Meningeal Neoplasms / diagnosis. Meningioma / diagnosis. Psychotic Disorders / etiology. Puerperal Disorders / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Pregnancy. Pregnancy Trimester, Third

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  • (PMID = 17267878.001).
  • [ISSN] 0029-7844
  • [Journal-full-title] Obstetrics and gynecology
  • [ISO-abbreviation] Obstet Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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5. Rajaraman P, Hutchinson A, Wichner S, Black PM, Fine HA, Loeffler JS, Selker RG, Shapiro WR, Rothman N, Linet MS, Inskip PD: DNA repair gene polymorphisms and risk of adult meningioma, glioma, and acoustic neuroma. Neuro Oncol; 2010 Jan;12(1):37-48
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  • [Title] DNA repair gene polymorphisms and risk of adult meningioma, glioma, and acoustic neuroma.
  • Although the etiology of primary brain tumors is largely unknown, prior studies suggest that DNA repair polymorphisms may influence risk of glioma.
  • Altered DNA repair is also likely to affect the risk of meningioma and acoustic neuroma, but these tumors have not been well studied.
  • We estimated the risk of glioma (n = 362), meningioma (n = 134), and acoustic neuroma (n = 69) in non-Hispanic whites with respect to 36 single nucleotide polymorphisms from 26 genes involved in DNA repair in a hospital-based, case-control study conducted by the National Cancer Institute.
  • We observed significantly increased risk of meningioma with the T variant of GLTSCR1 rs1035938 (OR(CT/TT) = 3.5; 95% confidence interval: 1.8-6.9; P(trend) .0006), which persisted after controlling for multiple comparisons (P = .019).
  • Significantly increased meningioma risk was also observed for the minor allele variants of ERCC4 rs1800067 (P(trend) .01); MUTYH rs3219466 (P(trend) .02), and PCNA rs25406 (P(trend) .03).
  • The NBN rs1805794 minor allele variant was associated with decreased meningioma risk (P(trend) .006).
  • Our results suggest that common DNA repair variants may affect the risk of adult brain tumors, especially meningioma.


6. Wigertz A, Lönn S, Hall P, Auvinen A, Christensen HC, Johansen C, Klaeboe L, Salminen T, Schoemaker MJ, Swerdlow AJ, Tynes T, Feychting M: Reproductive factors and risk of meningioma and glioma. Cancer Epidemiol Biomarkers Prev; 2008 Oct;17(10):2663-70
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  • [Title] Reproductive factors and risk of meningioma and glioma.
  • Female sex hormones have previously been suggested as possible risk factors for brain tumors, but published studies have reported conflicting results.
  • We conducted a population-based case-control study of glioma (n=626) and meningioma (n=906) cases and randomly selected controls stratified on age and geographic region (n=1,774) in Denmark, Finland, Norway, Sweden, and the United Kingdom.
  • Unconditional logistic regression was used to estimate odds ratios (OR) for glioma and meningioma in relation to reproductive factors.
  • Meningioma risk among women ages <50 years was increased in relation to number of pregnancies leading to a live birth (OR, 1.8; 95% CI: 1.1-2.8 for giving birth to 3 children compared with nulliparous women; P(trend) among parous women=0.01).
  • Menopausal status and age at menopause were not associated with meningioma or glioma risk.
  • Our findings imply that reproductive hormones may influence the occurrence of meningioma and glioma.
  • [MeSH-major] Brain Neoplasms / epidemiology. Brain Neoplasms / metabolism. Glioma / epidemiology. Glioma / metabolism. Meningioma / epidemiology. Meningioma / metabolism
  • [MeSH-minor] Adolescent. Adult. Age Factors. Aged. Case-Control Studies. Denmark / epidemiology. Female. Finland / epidemiology. Great Britain / epidemiology. Hormones / metabolism. Humans. Logistic Models. Menarche. Menopause. Middle Aged. Norway / epidemiology. Risk Factors. Sweden / epidemiology

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  • (PMID = 18843008.001).
  • [ISSN] 1055-9965
  • [Journal-full-title] Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
  • [ISO-abbreviation] Cancer Epidemiol. Biomarkers Prev.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Hormones
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7. Santhosh K, Kesavadas C, Radhakrishnan VV, Thomas B, Kapilamoorthy TR, Gupta AK: Rhabdoid and papillary meningioma with leptomeningeal dissemination. J Neuroradiol; 2008 Oct;35(4):236-9
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  • [Title] Rhabdoid and papillary meningioma with leptomeningeal dissemination.
  • Rhabdoid meningioma is a rare variant of meningioma classified as grade III under the new World Health Organization (WHO) classification of brain tumors.
  • We report here a case of rhabdoid meningioma in a young man, operated on twice previously, who presented with multiple CSF areas of seeding in the brain and spinal cord.
  • This particular histological subtype of meningioma has a poor prognosis and must be treated aggressively.
  • [MeSH-major] Meningeal Neoplasms / pathology. Meningioma / pathology. Rhabdoid Tumor / pathology
  • [MeSH-minor] Adult. Brain Neoplasms / secondary. Humans. Magnetic Resonance Imaging. Male. Neoplasm Invasiveness. Spinal Cord Neoplasms / secondary

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  • (PMID = 18325590.001).
  • [ISSN] 0150-9861
  • [Journal-full-title] Journal of neuroradiology. Journal de neuroradiologie
  • [ISO-abbreviation] J Neuroradiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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8. Guermazi A, Lafitte F, Miaux Y, Adem C, Bonneville JF, Chiras J: The dural tail sign--beyond meningioma. Clin Radiol; 2005 Feb;60(2):171-88
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  • [Title] The dural tail sign--beyond meningioma.
  • Most of the authors consider this so-called "dural tail sign" or "flare sign" almost specific for meningioma.
  • [MeSH-major] Brain Neoplasms / diagnosis. Dura Mater / pathology. Meningioma / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Adenoid Cystic / diagnosis. Chordoma / diagnosis. Esthesioneuroblastoma, Olfactory / diagnosis. Female. Glioma / diagnosis. Humans. Infection / radiography. Lymphatic Diseases / diagnosis. Male. Middle Aged. Nose Neoplasms / diagnosis. Pituitary Diseases / diagnosis. Sarcoma, Myeloid / diagnosis

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  • (PMID = 15664571.001).
  • [ISSN] 0009-9260
  • [Journal-full-title] Clinical radiology
  • [ISO-abbreviation] Clin Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 46
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9. Moradi A, Semnani V, Djam H, Tajodini A, Zali AR, Ghaemi K, Nikzad N, Madani-Civi M: Pathodiagnostic parameters for meningioma grading. J Clin Neurosci; 2008 Dec;15(12):1370-5
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  • [Title] Pathodiagnostic parameters for meningioma grading.
  • In this study the relationship between pathodiagnostic parameters, histological grade, and MIB-1 monoclonal antibody expression in meningioma diagnosed over 10 years in Shohada Hospital, Tehran, was assessed.
  • Histopathological study of completely resected meningiomas showed that loss of architecture, frequent mitotic figures, a high cellularity, increased nucleo-cytoplasmic ratio, a prominent nucleolus, brain invasion, and necrosis were correlated with the grade of the meningiomas.
  • [MeSH-major] Meningeal Neoplasms / diagnosis. Meningioma / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Female. Humans. Iran. Magnetic Resonance Imaging. Male. Middle Aged. Retrospective Studies. Ubiquitin-Protein Ligases / metabolism. X-Ray Microtomography. Young Adult

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  • (PMID = 18819804.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] EC 6.3.2.19 / MIB1 ligase, human; EC 6.3.2.19 / Ubiquitin-Protein Ligases
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10. Dutta D, Lee HN, Munshi A, Gupta T, Kane S, Sridhar E, Jalali R: Intracerebral cystic rhabdoid meningioma. J Clin Neurosci; 2009 Aug;16(8):1073-4
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  • [Title] Intracerebral cystic rhabdoid meningioma.
  • An MRI of the brain revealed a left temporal intracerebral cystic lesion with rim enhancement.
  • The patient was diagnosed as having an intracerebral cystic rhabdoid meningioma.
  • [MeSH-major] Brain Neoplasms / diagnosis. Brain Neoplasms / therapy. Meningioma / diagnosis. Meningioma / therapy. Rhabdoid Tumor / diagnosis. Rhabdoid Tumor / therapy
  • [MeSH-minor] Adult. Brain / pathology. Brain / radiation effects. Brain / surgery. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging

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  • (PMID = 19427788.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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11. Binello E, Bederson JB, Kleinman GM: Hemangiopericytoma: collision with meningioma and recurrence. Neurol Sci; 2010 Oct;31(5):625-30
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  • [Title] Hemangiopericytoma: collision with meningioma and recurrence.
  • Intracranial hemangiopericytomas are a rare type of primary brain tumor, representing only about 0.5% of all primary brain tumors.
  • Even more rare is the co-existence of two juxtaposed primary brain tumors, termed a "collision" tumor.
  • This report provides the first documentation in the literature of a hemangiopericytoma colliding with a meningioma, and recurring after treatment with gross total resection.
  • Results were classically representative of a hemangiopericytoma (World Health Organization grade II) and of a meningioma (World Health Organization grade I).
  • [MeSH-major] Brain Neoplasms / complications. Hemangiopericytoma / complications. Meningeal Neoplasms / complications. Meningioma / complications. Neoplasm Recurrence, Local / complications
  • [MeSH-minor] Adult. Antigens, CD34 / metabolism. Humans. Magnetic Resonance Imaging. Male. Recurrence

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  • (PMID = 20198500.001).
  • [ISSN] 1590-3478
  • [Journal-full-title] Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
  • [ISO-abbreviation] Neurol. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Antigens, CD34
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12. Takei H, Schmiege L, Buckleair L, Goodman JC, Powell SZ: Intracerebral schwannoma clinically and radiologically mimicking meningioma. Pathol Int; 2005 Aug;55(8):514-9
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  • [Title] Intracerebral schwannoma clinically and radiologically mimicking meningioma.
  • The differential diagnosis includes fibrous meningioma, solitary fibrous tumor, and ICS.
  • [MeSH-major] Brain Neoplasms / pathology. Meningeal Neoplasms / pathology. Meningioma / pathology. Neurilemmoma / pathology
  • [MeSH-minor] Adult. Antigens, CD34 / analysis. Calbindin 2. Diagnosis, Differential. Female. Frontal Lobe / chemistry. Frontal Lobe / pathology. Frontal Lobe / ultrastructure. Glial Fibrillary Acidic Protein / analysis. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Parietal Lobe / chemistry. Parietal Lobe / pathology. Parietal Lobe / ultrastructure. Pregnancy. Pregnancy Complications, Neoplastic. S100 Calcium Binding Protein G / analysis. S100 Proteins / analysis

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  • (PMID = 15998381.001).
  • [ISSN] 1320-5463
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / CALB2 protein, human; 0 / Calbindin 2; 0 / Glial Fibrillary Acidic Protein; 0 / S100 Calcium Binding Protein G; 0 / S100 Proteins
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13. van der Meij JJ, Boomars KA, van den Bosch JM, van Boven WJ, de Bruin PC, Seldenrijk CA: Primary pulmonary malignant meningioma. Ann Thorac Surg; 2005 Oct;80(4):1523-5
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  • [Title] Primary pulmonary malignant meningioma.
  • To exclude pulmonary metastasis of an intracranial meningioma, imaging studies of the brain should be performed.
  • We believe that only one primary pulmonary malignant meningioma in which a metastasis from the brain was excluded has been reported.
  • [MeSH-major] Bronchial Neoplasms / diagnosis. Bronchial Neoplasms / pathology. Meningioma / diagnosis. Meningioma / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Esophageal Neoplasms / pathology. Female. Humans. Liver Neoplasms / secondary. Magnetic Resonance Imaging. Meningeal Neoplasms / diagnosis. Neoplasm Invasiveness. Pleural Neoplasms / pathology. Treatment Outcome

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  • (PMID = 16181912.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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14. Menon G, Patro SN, Krishnakumar K, Kesavadas C, Nair S, Radhakrishnan VV: Subfrontal gangliocytoma masquerading as olfactory groove meningioma. Br J Neurosurg; 2009 Feb;23(1):79-82
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  • [Title] Subfrontal gangliocytoma masquerading as olfactory groove meningioma.
  • The conventional magnetic resonance imaging (MRI) appearance was suggestive of an olfactory groove meningioma.
  • [MeSH-major] Brain Neoplasms / pathology. Frontal Lobe / pathology. Ganglioneuroma / pathology. Meningeal Neoplasms / pathology. Meningioma / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans. Magnetic Resonance Imaging / methods. Male. Young Adult

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  • (PMID = 19234914.001).
  • [ISSN] 1360-046X
  • [Journal-full-title] British journal of neurosurgery
  • [ISO-abbreviation] Br J Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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15. Hosler MR, Turbin RE, Cho ES, Wolansky LJ, Frohman LP: Idiopathic hypertrophic pachymeningitis mimicking lymphoplasmacyte-rich meningioma. J Neuroophthalmol; 2007 Jun;27(2):95-8
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  • [Title] Idiopathic hypertrophic pachymeningitis mimicking lymphoplasmacyte-rich meningioma.
  • A 28-year-old woman with a 6-year history of optic neuropathy and 8 years of hearing loss had enhancing dural lesions around the brain stem and in both internal auditory canals on MRI.
  • Histopathology from cranial procedures performed in 1990 and 1993 was originally interpreted as inflammatory meningioma, now known as lymphoplasmacyte-rich meningioma (LRM).
  • [MeSH-major] Dura Mater / pathology. Meningeal Neoplasms / diagnosis. Meningioma / diagnosis. Meningitis / diagnosis. Plasma Cells / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Hypertrophy. Magnetic Resonance Imaging

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  • [CommentIn] J Neuroophthalmol. 2007 Jun;27(2):89-90 [17548989.001]
  • (PMID = 17548991.001).
  • [ISSN] 1070-8022
  • [Journal-full-title] Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
  • [ISO-abbreviation] J Neuroophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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16. Umansky F, Shoshan Y, Rosenthal G, Fraifeld S, Spektor S: Radiation-induced meningioma. Neurosurg Focus; 2008;24(5):E7
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  • [Title] Radiation-induced meningioma.
  • Emphasis is placed on meningiomas resulting from childhood treatment for primary brain tumor or tinea capitis, exposure to dental x-rays, and exposure to atomic explosions in Hiroshima and Nagasaki.
  • The authors review the typical presentation of patients with RIMs and discuss unique aspects of the surgical management of these tumors compared with sporadic meningioma, based on their clinical experience in treating these lesions.
  • [MeSH-major] Cranial Irradiation / adverse effects. Meningeal Neoplasms / etiology. Meningioma / etiology. Neoplasms, Radiation-Induced / etiology
  • [MeSH-minor] Adolescent. Adult. Alopecia / etiology. Brain Neoplasms / radiotherapy. Child. Cohort Studies. Dose-Response Relationship, Radiation. Female. Humans. Japan / epidemiology. Male. Neoplasm Invasiveness. Neoplasms, Second Primary / etiology. Neoplasms, Second Primary / radiotherapy. Neoplasms, Second Primary / surgery. Nuclear Warfare. Radiation Injuries / epidemiology. Radiation Injuries / etiology. Radiation Injuries / prevention & control. Radiography, Dental / adverse effects. Radiosurgery / adverse effects. Radiotherapy / trends. Tinea Capitis / radiotherapy

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  • [CommentIn] Neurosurg Focus. 2008;24(5):E6; discussion E6 [18447745.001]
  • (PMID = 18447746.001).
  • [ISSN] 1092-0684
  • [Journal-full-title] Neurosurgical focus
  • [ISO-abbreviation] Neurosurg Focus
  • [Language] eng
  • [Publication-type] Journal Article; Portraits; Review
  • [Publication-country] United States
  • [Number-of-references] 82
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17. Mourad A, Guichard JP, Vignal C, Bousser MG, Vahedi K: Sphenoid and optic nerve sheath meningioma revealed by recurrent brain infarctions. Rev Neurol (Paris); 2009 Dec;165(12):1092-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sphenoid and optic nerve sheath meningioma revealed by recurrent brain infarctions.
  • Meningioma, though benign, may invade adjacent structures such as bone, soft tissues, dural sinuses and arteries.
  • However brain infarctions secondary to meningioma involving the cavernous sinus and encasing and narrowing the intracranial carotid artery are rare.
  • We report the case of a young man with recurrent left carotid artery infarctions due to a left sphenoid meningioma infiltrating the posterior optic nerve sheath through the optic canal and circumscribing the intracranial carotid artery.
  • The patient had a gradually progressive occlusion of the middle cerebral artery, the distal internal carotid artery and finally the anterior cerebral artery ipsilateral to the sphenoid meningioma.
  • [MeSH-major] Cerebral Infarction / etiology. Meningioma / pathology. Optic Nerve Neoplasms / pathology. Sphenoid Bone / pathology
  • [MeSH-minor] Adult. Aphasia / etiology. Carotid Arteries / pathology. Carotid Artery Diseases / radiography. Carotid Artery Diseases / surgery. Cerebral Arteries / pathology. Decompression, Surgical. Humans. Male. Microsurgery. Orbit / radiography. Orbit / surgery. Recurrence. Tomography, X-Ray Computed

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  • (PMID = 19324384.001).
  • [ISSN] 0035-3787
  • [Journal-full-title] Revue neurologique
  • [ISO-abbreviation] Rev. Neurol. (Paris)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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18. Hirunwiwatkul P, Trobe JD, Blaivas M: Lymphoplasmacyte-rich meningioma mimicking idiopathic hypertrophic pachymeningitis. J Neuroophthalmol; 2007 Jun;27(2):91-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lymphoplasmacyte-rich meningioma mimicking idiopathic hypertrophic pachymeningitis.
  • Brain MRI showed meningeal thickening that involved the optic nerves and chiasm and enveloped and displaced the brainstem as far caudally as the foramen magnum.
  • The diffuse extensive nature of the lesion suggested an inflammatory process such as idiopathic hypertrophic pachymeningitis (IHP), but anterior temporal brain biopsy disclosed a relatively high proportion of meningothelial cells with islands of polyclonal inflammatory reaction consistent with a diagnosis of lymphoplasmacyte-rich meningioma (LRM), a rare variant.
  • [MeSH-major] Dura Mater / pathology. Meningeal Neoplasms / diagnosis. Meningioma / diagnosis. Meningitis / diagnosis. Plasma Cells / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Hypertrophy. Magnetic Resonance Imaging. Male

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  • [CommentIn] J Neuroophthalmol. 2007 Jun;27(2):89-90 [17548989.001]
  • (PMID = 17548990.001).
  • [ISSN] 1070-8022
  • [Journal-full-title] Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
  • [ISO-abbreviation] J Neuroophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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19. Olivera M, Martínez C, Molina JA, Alonso-Navarro H, Jiménez-Jiménez FJ, García-Martín E, Benítez J, Agúndez JA: Increased frequency of rapid acetylator genotypes in patients with brain astrocytoma and meningioma. Acta Neurol Scand; 2006 May;113(5):322-6
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  • [Title] Increased frequency of rapid acetylator genotypes in patients with brain astrocytoma and meningioma.
  • We investigated the association between the genetic NAT2 polymorphism and brain tumors by analysis of genomic DNA from 71 brain tumor patients and 258 healthy controls.
  • A higher number of individuals carrying functional NAT2 genes, and therefore with a rapid acetylation phenotype, was found in brain tumor patients vs healthy volunteers (OR 1.79, 95% CI 1.05-3.05; P < 0.05).
  • This is observed either for patients suffering from meningioma or astrocytoma, and this is due to an increase of the wild-type NAT2*4 allelic variant frequency (OR 1.48, 95% CI 0.99-2.19), and a reduction of the commonest defective allelic variant NAT2*5B in the brain tumor patients, compared with healthy subjects (OR 0.54, 95% CI 0.37-0.80).
  • CONCLUSIONS: This observation indicates that NAT2 could be considered as a low-penetrance gene for brain tumors, and that individuals carrying rapid acetylation alleles are at increased risk of developing brain tumors.
  • [MeSH-major] Arylamine N-Acetyltransferase / genetics. Astrocytoma / genetics. Brain Neoplasms / genetics. Meningeal Neoplasms / genetics. Meningioma / genetics. Polymorphism, Single Nucleotide / genetics
  • [MeSH-minor] Adult. Aged. Case-Control Studies. Female. Humans. Male. Middle Aged. Penetrance. Polymerase Chain Reaction

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  • (PMID = 16629768.001).
  • [ISSN] 0001-6314
  • [Journal-full-title] Acta neurologica Scandinavica
  • [ISO-abbreviation] Acta Neurol. Scand.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] EC 2.3.1.5 / Arylamine N-Acetyltransferase; EC 2.3.1.5 / NAT2 protein, human
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20. Bollag RJ, Vender JR, Sharma S: Anaplastic meningioma: progression from atypical and chordoid morphotype with morphologic spectral variation at recurrence. Neuropathology; 2010 Jun;30(3):279-87
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anaplastic meningioma: progression from atypical and chordoid morphotype with morphologic spectral variation at recurrence.
  • Recent literature evokes two pathways to disease progression in meningiomas akin to a comparable paradigm in gliomas, but without similar prognostic connotation: de novo anaplastic meningioma (better prognosis), and transformed meningioma (worse prognosis).
  • We present two adult cases of transformed meningiomas that display a spectrum of morphologic progression.
  • Case 1 at presentation showed a random admixture of meningothelial, atypical and anaplastic meningioma.
  • The tumor recurred as anaplastic meningioma.
  • Case 2 presented as a chordoid meningioma, but recurred as anaplastic meningioma mainly at the invasive front in transition with residual chordoid pattern.
  • In accordance with the dire prognosis for anaplastic meningioma, both patients succumbed to their disease within 2 months of recurrence.
  • The present study highlights two main points: First, that proper recognition of focal high-grade areas in a heterogeneous low-grade meningioma (case 1) provides critical morphologic clues to spatial histologic progression and predicts aggressive biologic behavior, as evidenced by progression to frankly anaplastic meningioma at recurrence.
  • Second, the presence of papillary in addition to anaplastic areas, in the recurrence of a previously diagnosed chordoid meningioma supports the ostensibly heightened transforming potential of grade II meningiomas, but also reflects on the morphologic heterogeneity of high-grade meningiomas, and their potentially diverse pathways of progression.
  • We propose that grading of meningiomas as outlined by WHO is of more critical prognostic import than histologic sub-typing, and must include a thorough survey of the tumor-brain interface.
  • Future molecular genetic correlates, akin to those characterized in gliomas, could help stratify prognostic subcategories to refine meningioma grading, and govern optimal therapeutic strategies.
  • [MeSH-major] Choroid Plexus Neoplasms / diagnosis. Choroid Plexus Neoplasms / pathology. Meningeal Neoplasms / diagnosis. Meningeal Neoplasms / pathology. Meningioma / diagnosis. Meningioma / pathology. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / pathology

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  • (PMID = 19780983.001).
  • [ISSN] 1440-1789
  • [Journal-full-title] Neuropathology : official journal of the Japanese Society of Neuropathology
  • [ISO-abbreviation] Neuropathology
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article
  • [Publication-country] Australia
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21. Liu Y, Tian RF, Li YM, Liu WP, Cao L, Yang XL, Cao WD, Zhang X: The expression of seven 14-3-3 isoforms in human meningioma. Brain Res; 2010 Jun 8;1336:98-102
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The expression of seven 14-3-3 isoforms in human meningioma.
  • 14-3-3 proteins comprise a large family of highly conserved, acidic polypeptides, expressed in all eukaryotic organisms, with highest concentration found in the brain.
  • However, the expression of seven 14-3-3 isoforms in meningioma still remains unknown.
  • This study is the first examination of 14-3-3 isoforms in three grades of meningioma by immunohistochemistry.
  • 14-3-3epsilon, zeta and theta were specifically expressed in meningioma, and their expression levels increased with the increase of pathological grade of meningioma.
  • The 14-3-3 eta, beta, gamma and sigma isoforms were negatively expressed in meningioma.
  • In conclusion, The 14-3-3 epsilon, zeta and theta may be involved in tumorigenesis of meningioma and be efficient markers for predicting the degree of malignancy in meningioma.
  • [MeSH-major] 14-3-3 Proteins / biosynthesis. Meningeal Neoplasms / metabolism. Meningeal Neoplasms / pathology. Meningioma / metabolism. Meningioma / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Biomarkers, Tumor / analysis. Child. Female. Humans. Immunohistochemistry. Male. Middle Aged. Protein Isoforms / biosynthesis. Young Adult

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  • [Copyright] Copyright 2010 Elsevier B.V. All rights reserved.
  • (PMID = 20388496.001).
  • [ISSN] 1872-6240
  • [Journal-full-title] Brain research
  • [ISO-abbreviation] Brain Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / 14-3-3 Proteins; 0 / Biomarkers, Tumor; 0 / Protein Isoforms
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22. Chang JH, Kim JA, Chang JW, Park YG, Kim TS: Sylvian meningioma without dural attachment in an adult. J Neurooncol; 2005 Aug;74(1):43-5
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  • [Title] Sylvian meningioma without dural attachment in an adult.
  • This paper presents a rare case of a sylvian meningioma in a 35-year-old male.
  • The tumor was excised, and a histological diagnosis of a transitional meningioma without a malignancy was made.
  • A Sylvian meningioma without dural attachment is quite rare, and a preoperative differentiation of this lesion is generally difficult.
  • [MeSH-major] Dura Mater / pathology. Meningeal Neoplasms / pathology. Meningioma / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. Middle Cerebral Artery / pathology. Neoplasm Recurrence, Local / surgery

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  • (PMID = 16078106.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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23. Kumar R, Kamdar D, Madden L, Hills C, Crooks D, O'Brien D, Greenman J: Th1/Th2 cytokine imbalance in meningioma, anaplastic astrocytoma and glioblastoma multiforme patients. Oncol Rep; 2006 Jun;15(6):1513-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Th1/Th2 cytokine imbalance in meningioma, anaplastic astrocytoma and glioblastoma multiforme patients.
  • Serum samples from 61 newly diagnosed patients with brain tumours and 50 age- and sex-matched non-tumour controls were analysed by ELISA for circulating levels of interleukin-12 (IL-12p70 and p40) and interleukin-10 (IL-10); pivotal Th1 and Th2 cytokines, respectively.
  • Patients were divided into various groups depending on their histological diagnosis: meningioma (n=11), anaplastic astrocytoma (n=4) and glioblastoma multiforme (GBM; n=46).
  • Significant reduction in serum IL-12 was seen in all groups as compared with the controls: meningioma, p=0.03; anaplastic astrocytoma, p<0.001; and GBM, p<0.001.
  • This study shows that patients with advanced primary intracranial malignancies have decreased circulating IL-12 and increased circulating IL-10, demonstrating that brain tumours have a major systemic effect on the immune system.
  • [MeSH-major] Astrocytoma / immunology. Brain Neoplasms / immunology. Glioblastoma / immunology. Interleukin-10 / blood. Interleukin-12 / blood. Meningioma / immunology. Th1 Cells / immunology. Th2 Cells / immunology
  • [MeSH-minor] Adult. Aged. Cohort Studies. Female. Humans. Male. Middle Aged


24. Bosnjak R, Derham C, Popović M, Ravnik J: Spontaneous intracranial meningioma bleeding: clinicopathological features and outcome. J Neurosurg; 2005 Sep;103(3):473-84
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spontaneous intracranial meningioma bleeding: clinicopathological features and outcome.
  • OBJECT: The aim of this study was to determine the clinicopathological features of patients with intracranial bleeding from unsuspected meningioma and to relate these data to surgery-related outcome.
  • METHODS: The authors report on two cases in which hemorrhage of an unsuspected meningioma occurred in the tentorial ridge and in the falx, and they discuss the details of 143 cases described in the literature.
  • A bleeding propensity index of the meningioma, related to the patient's age, sex, and the lesion's intracranial location and histological type was computed as a ratio between the frequencies of bleeding meningioma and all meningiomas.
  • CONCLUSIONS: The mortality rate in preoperatively conscious patients (those in whom acute deterioration and irreversible brain damage were prevented by early diagnosis and definitive surgery) was similar (< 3% in the CT scanning era) to that documented in cases in which meningiomas did not bleed.
  • One-stage total removal of the hemorrhagic meningioma and hematoma is the treatment of choice in such patients.
  • [MeSH-major] Intracranial Hemorrhages / etiology. Meningeal Neoplasms / surgery. Meningioma / surgery
  • [MeSH-minor] Adolescent. Adult. Age Factors. Aged. Consciousness. Female. Humans. Male. Middle Aged. Prognosis. Retrospective Studies. Risk Factors. Sex Factors. Survival

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  • (PMID = 16235680.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 109
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25. Kano T, Nakazato Y, Tamura M, Ohye C, Zama A, Saito F, Tomizawa S: Ultrastructural and immunohistochemical study of an adult case of chordoid meningioma. Brain Tumor Pathol; 2009;26(1):37-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ultrastructural and immunohistochemical study of an adult case of chordoid meningioma.
  • The tumor was diagnosed as a chordoid meningioma, and the second surgical specimen showed increasing nuclear atypia and mitoses in tumor cells.
  • [MeSH-major] Meningioma / pathology

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  • (PMID = 19408096.001).
  • [ISSN] 1861-387X
  • [Journal-full-title] Brain tumor pathology
  • [ISO-abbreviation] Brain Tumor Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / S100 Proteins; 0 / Vimentin; 68238-35-7 / Keratins
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26. Jiang YG, Xiang J, Wen F, Zhang LY: Microsurgical excision of the large or giant cerebellopontine angle meningioma. Minim Invasive Neurosurg; 2006 Feb;49(1):43-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Microsurgical excision of the large or giant cerebellopontine angle meningioma.
  • OBJECTIVE: The object of this study was to analyze the therapeutic effects of microsurgical excision in cases with the large or giant cerebellopontine angle meningioma.
  • METHODS: We retrospectively analyzed the 56 patients who suffered from the large or giant cerebellopontine angle meningioma and underwent the microsurgical therapy, for which the suboccipital-retrosigmoidal approach was adopted in 38 cases, the temporal-occipital craniotomy, presigmoidal approach in 6 cases, the temporal-occipital craniotomy, inferotemporal tentorium cerebelli approach in 8 cases, and the temporal-occipital craniotomy, supratentorial or infratentorial allied approach in 4 cases.
  • CONCLUSION: A rationally selected surgical approach, a microscopic technology applied in the operation to appropriately treat and protect vein, nerve and brain stem, which can ideally excise the tumors, together can increase the survival ability of patients.
  • [MeSH-major] Cerebellar Neoplasms / surgery. Cerebellopontine Angle. Meningeal Neoplasms / surgery. Meningioma / surgery. Microsurgery
  • [MeSH-minor] Adolescent. Adult. Craniotomy. Female. Follow-Up Studies. Humans. Male. Middle Aged. Retrospective Studies. Treatment Outcome

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  • (PMID = 16547882.001).
  • [ISSN] 0946-7211
  • [Journal-full-title] Minimally invasive neurosurgery : MIN
  • [ISO-abbreviation] Minim Invasive Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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27. Chamberlain MC, Tsao-Wei DD, Groshen S: Salvage chemotherapy with CPT-11 for recurrent meningioma. J Neurooncol; 2006 Jul;78(3):271-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Salvage chemotherapy with CPT-11 for recurrent meningioma.
  • BACKGROUND: A prospective Phase II study of irinotecan (CPT-11) in adult patients with recurrent surgery and radiotherapy-refractory WHO Grade I meningioma.
  • METHODS: Sixteen patients (5 men; 11 women) ages 48-70 years (median 62.5), with recurrent meningioma were treated.
  • Using CPT-11 in this moderately toxic dose schedule failed to demonstrate efficacy in this cohort of adult patients with recurrent surgery and radiotherapy-refractory meningioma.
  • [MeSH-major] Antineoplastic Agents, Phytogenic / administration & dosage. Brain Neoplasms / drug therapy. Camptothecin / analogs & derivatives. Meningioma / drug therapy. Neoplasm Recurrence, Local / drug therapy. Salvage Therapy

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  • (PMID = 16628476.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase II; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Anticonvulsants; 0 / Antineoplastic Agents, Phytogenic; 7673326042 / irinotecan; XT3Z54Z28A / Camptothecin
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28. Fischer BR, Palkovic S, Holling M, Niederstadt T, Jeibmann A, Wassmann H: Coexistence of cerebral aneurysm and meningioma--pure accident? Clin Neurol Neurosurg; 2009 Oct;111(8):647-54
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Coexistence of cerebral aneurysm and meningioma--pure accident?
  • OBJECTIVES: Coexisting intracerebral aneurysms and meningiomas occur relatively rarely, without a clear relationship, although an aneurysm can be located within a meningioma.
  • PATIENTS AND METHODS: Ninety-five patients with coexistent meningioma and aneurysm were found in the National Library of Medicine, and 11 more patients were retrieved from our own database.
  • CONCLUSIONS: The coexistence of meningioma and aneurysm seems to be a coincidence.
  • [MeSH-major] Brain / pathology. Brain Neoplasms / complications. Intracranial Aneurysm / complications. Meningioma / complications
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Cohort Studies. Female. Humans. Male. Microsurgery / trends. Middle Aged. Neurosurgical Procedures / trends. Retrospective Studies. Sex Distribution. Young Adult

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  • (PMID = 19576683.001).
  • [ISSN] 1872-6968
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 75
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29. Ono K, Hatada J, Minamimura K, Ohara I, Wada K: Delayed enlargement of brain edema after resection of intracranial meningioma: two case reports. Neurol Med Chir (Tokyo); 2009 Oct;49(10):478-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Delayed enlargement of brain edema after resection of intracranial meningioma: two case reports.
  • Two patients underwent uneventful total removal of convexity or trigone meningioma, but subsequently edema enlarged causing symptoms 3-4 weeks later.
  • VEGF secreted by the tumor might have resulted in spread of inflammation due to MCH in the brain parenchyma.
  • However, the risk of this phenomenon can probably be minimized by ensuring that MCH is removed as effectively as possible after use, or by refraining from use in the brain parenchyma and by taking care to connect the residual cavity to the ventricular system, particularly if the tumor contacts a cerebral ventricle.
  • [MeSH-major] Brain Edema / etiology. Cerebral Ventricle Neoplasms / complications. Meningeal Neoplasms / complications. Meningioma / complications. Postoperative Complications / etiology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Biomarkers, Tumor / metabolism. Brain / pathology. Brain / physiopathology. Brain / surgery. Cerebrospinal Fluid Pressure / physiology. Collagen / adverse effects. Encephalitis / etiology. Encephalitis / pathology. Encephalitis / physiopathology. Humans. Hydrocephalus, Normal Pressure / etiology. Hydrocephalus, Normal Pressure / pathology. Hydrocephalus, Normal Pressure / physiopathology. Lateral Ventricles / pathology. Lateral Ventricles / surgery. Magnetic Resonance Imaging. Male. Middle Aged. Time Factors. Vascular Endothelial Growth Factor A / analysis. Vascular Endothelial Growth Factor A / metabolism. Young Adult

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  • (PMID = 19855147.001).
  • [ISSN] 1349-8029
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Vascular Endothelial Growth Factor A; 9007-34-5 / Collagen
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30. Suga Y, Tsutsumi S, Higo T, Kondo A, Abe Y, Yasumoto Y, Ito M: [Huge falx meningioma resected en bloc following acute brain swelling: a case report]. No Shinkei Geka; 2008 Sep;36(9):819-23
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  • [Title] [Huge falx meningioma resected en bloc following acute brain swelling: a case report].
  • Surgery of a meningioma is composed of four essential consecutive steps; devascularization, detachment, debulking, and dissection.
  • However, this is not the case with a huge meningioma in which circumferential devascularization and detachment may be difficult to complete before debulking is attempted.
  • We report a case of a 37-year-old female presented headache, memory disturbance, and character change and sustaining a huge falx meningioma, with hypervascular appearance.
  • Intraoperatively her blood pressure decreased to 45/30 mmHg due to profuse bleeding caused by "premature debulking" followed by significant brain swelling, which pushed out the tumor from the underlying brain after detachment of the tumor from the falx, and, consequently, yielded en bloc removal like a birth delivery.
  • The histopathological diagnosis was angiomatous meningioma with prominent capillary proliferation without findings of celluar atypia.
  • We thought that relative hyperemia in the brain surrounding the tumor, which was induced by the craniotomy, and acute brain ischemia caused by the intraoperative significant hypotension, might facilitate en bloc removal.
  • We should be aware that huge meningiomas may cause intraoperative acute brain swelling as well as significant blood loss.
  • [MeSH-major] Brain Edema / etiology. Intraoperative Complications / etiology. Meningeal Neoplasms / complications. Meningeal Neoplasms / surgery. Meningioma / complications. Meningioma / surgery
  • [MeSH-minor] Acute Disease. Adult. Blood Loss, Surgical. Female. Humans

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  • (PMID = 18800638.001).
  • [ISSN] 0301-2603
  • [Journal-full-title] No shinkei geka. Neurological surgery
  • [ISO-abbreviation] No Shinkei Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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31. Dange N, Mahore A, Kansal R, Goel A: Brain herniation through the anterior cranial floor in a long-standing frontal falcine meningioma. J Clin Neurosci; 2009 Sep;16(9):1242-3
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  • [Title] Brain herniation through the anterior cranial floor in a long-standing frontal falcine meningioma.
  • Brain herniation through the incisural cisterns in raised intracranial tension is well known, but brain herniation through the cribriform plate is rare.
  • We report a patient with an anterior falcine meningioma who suffered brain tissue herniation through the cribriform plate with extension into the paranasal air sinuses.
  • [MeSH-major] Brain Diseases / pathology. Hernia / pathology. Meningioma / pathology. Skull Base Neoplasms / pathology
  • [MeSH-minor] Adult. Craniotomy. Female. Herniorrhaphy. Humans. Magnetic Resonance Imaging

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  • (PMID = 19539474.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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32. Kozler P, Benes V, Netuka D, Kramár F, Charvát F: Intracranial meningioma surgery outcome--the impact of preoperative neuroimaging. Prague Med Rep; 2006;107(3):327-34
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  • [Title] Intracranial meningioma surgery outcome--the impact of preoperative neuroimaging.
  • The present study is aimed at finding radiological parameters which could provide indirect information on invasive growth of meningioma, relevant enough to predict the possible risk of postoperative neurological deficit development.
  • The cohort was composed of 40 consecutive adult patients of comparable general condition parameters (age 18-75 years, KRS 70-100, ASA 1-2) with meningiomas attacking with the whole of their volume solely the brain tissue.
  • As follows from the outcome, meningioma growth in the eloquent area and the presence of peritumoral oedema are the two adverse parameters predicting the development of postoperative neurological deficit.
  • In contrast, dural type of vascularisation, visible tumour-brain interface, meningioma growing in a non-eloquent area and the absence of peritumoral oedema are favourable predictive parameters.
  • [MeSH-major] Magnetic Resonance Imaging. Meningeal Neoplasms / diagnosis. Meningioma / diagnosis
  • [MeSH-minor] Adult. Aged. Female. Humans. Male. Middle Aged

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  • (PMID = 17385405.001).
  • [ISSN] 1214-6994
  • [Journal-full-title] Prague medical report
  • [ISO-abbreviation] Prague Med Rep
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Czech Republic
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33. Bodner-Adler B, Lozano P, Bodner K, Zeisler H: Primary uterine leiomyosarcoma and primary atypical meningioma diagnosed during pregnancy. Anticancer Res; 2008 Sep-Oct;28(5B):3083-5
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  • [Title] Primary uterine leiomyosarcoma and primary atypical meningioma diagnosed during pregnancy.
  • The incidence of meningioma during pregnancy is comparable with that in nonpregnant women of the same age group.
  • We report a case of both--a primary uterine leiomyosarcoma and additionally an atypical meningioma of the brain both diagnosed during pregnancy.
  • During caesarean section a pedunculated uterine fibroid was removed and total gross resection due to the brain tumour was also performed.
  • Histopathological diagnosis of both tumours revealed an atypical meningioma of the brain and a uterine leiomyosarcoma.
  • [MeSH-major] Brain Neoplasms / diagnosis. Leiomyosarcoma / diagnosis. Meningioma / diagnosis. Neoplasms, Multiple Primary / diagnosis. Pregnancy Complications, Neoplastic / diagnosis. Uterine Neoplasms / diagnosis
  • [MeSH-minor] Adult. Female. Humans. Pregnancy


34. Al-Habib A, Lach B, Al Khani A: Intracerebral rhabdoid and papillary meningioma with leptomeningeal spread and rapid clinical progression. Clin Neuropathol; 2005 Jan-Feb;24(1):1-7
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  • [Title] Intracerebral rhabdoid and papillary meningioma with leptomeningeal spread and rapid clinical progression.
  • OBJECTIVE AND IMPORTANCE: Rhabdoid meningioma (RM) is a relatively new, Grade III tumor entity according to the latest WHO classification.
  • We report rhabdoid and partly papillary, highly anaplastic, intracerebral meningioma with diffuse leptomeningeal spread and distant SCF metastasis to the cervical cord.
  • CLINICAL PRESENTATION: This 27-year-old female was admitted to the hospital with radiological findings suggestive of a primary brain tumor or a metastasis.
  • RESULTS: Histological examination revealed rhabdoid and papillary meningioma with high proliferation rate (80% of MIB1-positive cells), necrosis and extensive brain invasion.
  • CONCLUSION: This is a rare example of mixed, rhabdoid and papillary variant of meningioma, located entirely within the brain parenchyma and accompanied by a fulminant clinical course.
  • [MeSH-major] Arachnoid / pathology. Frontal Lobe. Meningeal Neoplasms / secondary. Meningeal Neoplasms / surgery. Meningioma / secondary. Meningioma / surgery. Pia Mater / pathology
  • [MeSH-minor] Adult. Brain / pathology. Disease Progression. Female. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Neoplasm Invasiveness. Neoplasm Recurrence, Local. Time Factors

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  • (PMID = 15696777.001).
  • [ISSN] 0722-5091
  • [Journal-full-title] Clinical neuropathology
  • [ISO-abbreviation] Clin. Neuropathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 34
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35. McIver JI, Scheithauer BW, Atkinson JL: Deep Sylvian fissure chordoid meningioma: case report. Neurosurgery; 2005 Nov;57(5):E1064; discussion E1064
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  • [Title] Deep Sylvian fissure chordoid meningioma: case report.
  • OBJECTIVE AND IMPORTANCE: A case of chordoid meningioma originating in the right sylvian fissure is reported.
  • This is the first reported case of a chordoid meningioma without dural attachment arising in the sylvian fissure.
  • A heterogeneously enhancing right frontotemporal mass was identified on magnetic resonance imaging of the brain.
  • [MeSH-minor] Adult. Humans. Magnetic Resonance Imaging / methods. Male. Meningioma. Neurosurgery / methods

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  • (PMID = 16284544.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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36. Senbokuya N, Asahara T, Uchida M, Yagishita T, Naganuma H: Atypical meningioma with large cyst. Case report. Neurol Med Chir (Tokyo); 2006 Mar;46(3):147-51
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  • [Title] Atypical meningioma with large cyst. Case report.
  • The preoperative diagnosis was cystic falx meningioma.
  • The tumor was totally resected, but most of the cyst wall adhered tightly to the surrounding brain and could not be removed.
  • Histological examination revealed atypical meningioma and tumor cells in the cyst wall.
  • [MeSH-major] Cysts / complications. Meningeal Neoplasms / complications. Meningioma / complications
  • [MeSH-minor] Adult. Humans. Male

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  • (PMID = 16565585.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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37. Jain D, Sharma MC, Sarkar C, Suri V, Garg A, Singh M, Sharma BS, Mahapatra AK: Clear cell meningioma, an uncommon variant of meningioma: a clinicopathologic study of nine cases. J Neurooncol; 2007 Feb;81(3):315-21
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  • [Title] Clear cell meningioma, an uncommon variant of meningioma: a clinicopathologic study of nine cases.
  • AIMS: Clear cell meningioma (CCM) is an uncommon variant of meningioma, which affect younger patients, occur more often in spinal or cerebello pontine locations and shows a higher recurrence rate.
  • Radiologically lesions showed homogenous enhancement and were isointense to brain parenchyma.
  • CONCLUSIONS: CCM is a rare variant of meningioma with poor outcome.
  • [MeSH-major] Meningeal Neoplasms / pathology. Meningioma / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Female. Humans. Immunohistochemistry. Male. Middle Aged. Sex Factors. Tomography, X-Ray Computed

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  • (PMID = 16955223.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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38. Bluhm EC, Zahm SH, Fine HA, Black PM, Loeffler JS, Shapiro WR, Selker RG, Inskip PD: Personal hair dye use and risks of glioma, meningioma, and acoustic neuroma among adults. Am J Epidemiol; 2007 Jan 1;165(1):63-71
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  • [Title] Personal hair dye use and risks of glioma, meningioma, and acoustic neuroma among adults.
  • Risks for brain tumors are not well understood.
  • The authors investigated associations between use of synthetic hair dyes and risk of brain tumors in a hospital-based case-control study.
  • The study included adults newly diagnosed with glioma (n = 489), meningioma (n = 197), or acoustic neuroma (n = 96) between 1994 and 1998 at three urban US hospitals and 799 controls.
  • There was no consistent pattern of elevated odds ratios for glioma, meningioma, or acoustic neuroma with use or prolonged use of permanent, semipermanent, temporary, or gradual hair dyes.
  • Overall, there was little consistent evidence for an association of synthetic hair dye use with glioma, meningioma, or acoustic neuroma.
  • [MeSH-major] Brain Neoplasms / epidemiology. Environmental Exposure / adverse effects. Glioma / epidemiology. Hair Dyes / toxicity. Meningioma / epidemiology. Neuroma, Acoustic / epidemiology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Arizona / epidemiology. Beauty Culture. Boston / epidemiology. Case-Control Studies. Female. Humans. Male. Middle Aged. Pennsylvania / epidemiology. Risk Assessment. Risk Factors


39. Chen YY, Tiang XY, Li Z, Luo BN, Huang Q: Sporadic meningioangiomatosis-associated atypical meningioma mimicking parenchymal invasion of brain: a case report and review of the literature. Diagn Pathol; 2010;5:39
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  • [Title] Sporadic meningioangiomatosis-associated atypical meningioma mimicking parenchymal invasion of brain: a case report and review of the literature.
  • Meningioangiomatosis is a rare hamartomatous lesion or meningiovascular malformation in brain.
  • In extremely rare condition, meningioma may occur together with meningioangiomatosis, and only 19 cases have been described in English literature until now.
  • We now report a case of meningioangiomatosis-associated meningioma with atypical and clear cell variant.
  • Microscopically, parts of lesions were atypical and clear cell meningioma corresponding to WHO grade II.
  • The adjacent brain parenchyma showed the histological features of meningioangiomatosis.
  • Neoplastic cells in atypical meningioma area were immunoreactive to epithelial membrane antigen (EMA) with high MIB-1 index of up to 20%.
  • The diagnosis of atypical meningioma associated with sporadic meningioangiomatosis was made.
  • To our knowledge, this is the first case of a meningioangiomatosis-associated meningioma with atypical and clear cell variant component to be described.
  • Meningioangiomatosis-associated meningioma is more likely to occur in younger patients and histologically to mimic parenchymal invasion of brain.
  • We suggest that postoperative radiotherapy or chemotherapy should be given careful consideration to avoid over-treatment due to erroneously interpret as malignant meningioma.
  • [MeSH-major] Brain Neoplasms / diagnosis. Central Nervous System Vascular Malformations / diagnosis. Cerebral Cortex / pathology. Meningeal Neoplasms / diagnosis. Meningioma / diagnosis
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Male. Neoplasm Invasiveness. Treatment Outcome

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  • [Cites] J Neurosurg. 2000 Apr;92(4):706-10 [10761664.001]
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  • (PMID = 20565869.001).
  • [ISSN] 1746-1596
  • [Journal-full-title] Diagnostic pathology
  • [ISO-abbreviation] Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2904739
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40. Asgari S, Bassiouni H, Hunold A, Klassen D, Stolke D, Sandalcioglu IE: Extensive brain swelling with neurological deterioration after intracranial meningioma surgery - venous complication or 'unspecific' increase in tissue permeability. Zentralbl Neurochir; 2008 Feb;69(1):22-9
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  • [Title] Extensive brain swelling with neurological deterioration after intracranial meningioma surgery - venous complication or 'unspecific' increase in tissue permeability.
  • OBJECTIVE: We retrospectively analyzed a series of patients who deteriorated after resection of an intracranial meningioma due to extensive brain edema (EBE) with regard to etiology of the neurological worsening and outcome.
  • METHODS: Out of a series of 376 consecutive patients who underwent resection of an intracranial meningioma, 13 (3.5%) experienced postoperative deterioration due to EBE which necessitated prolonged artificial ventilation, tracheal reintubation, or decompressive craniectomy.
  • CONCLUSION: Extensive brain swelling during or after intracranial meningioma surgery may be due to VI or possibly due to increased postoperative tissue permeability.
  • [MeSH-major] Brain Edema / etiology. Brain Neoplasms / surgery. Cerebrovascular Disorders / etiology. Meningioma / surgery. Nervous System Diseases / etiology. Neurosurgical Procedures / adverse effects. Postoperative Complications / epidemiology
  • [MeSH-minor] Adult. Aged. Cerebral Infarction / etiology. Cerebral Infarction / pathology. Cerebral Veins / pathology. Constriction. Data Interpretation, Statistical. Female. Follow-Up Studies. Glasgow Outcome Scale. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Retrospective Studies. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 18393161.001).
  • [ISSN] 0044-4251
  • [Journal-full-title] Zentralblatt für Neurochirurgie
  • [ISO-abbreviation] Zentralbl. Neurochir.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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41. Chen CJ, Tseng YC, Hsu HL, Jung SM: Microcystic meningioma: importance of obvious hypointensity on T1-weighted magnetic resonance images. J Comput Assist Tomogr; 2008 Jan-Feb;32(1):130-4
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  • [Title] Microcystic meningioma: importance of obvious hypointensity on T1-weighted magnetic resonance images.
  • PURPOSE: To investigate the sensitivity and specificity of various magnetic resonance imaging findings for microcystic meningioma.
  • METHODS: Magnetic resonance images of 26 patients with microcystic meningioma (8 from our series and 18 from the literature) and 32 control subjects with other types of meningiomas were evaluated for obvious hypointensity relative to the cerebral cortex on T1-weighted images (T1WIs), obvious hyperintensity relative to the cerebral cortex on T2-weighted images (T2WIs), a radial or sunburst vascular pattern, marginal and reticular enhancement, severe peritumoral brain edema, and the dural tail sign.
  • The sensitivity, specificity, positive predictive value, and negative predictive value of these findings in the diagnosis of microcystic meningioma were calculated.
  • RESULTS: The frequencies of obvious hypointensity on T1WI, obvious hyperintensity on T2WI, marginal and reticular enhancement, and severe peritumoral brain edema significantly differed between the microcystic and control groups (all P < 0.005).
  • Sensitivities and specificities of hypointensity on T1WI and hyperintensity on T2WI in the diagnosis of microcystic meningioma were greater than 87%.
  • After multivariate analysis, obvious hypointensity on T1WI was the only significant predictor of microcystic meningioma, with an odds ratio of 75.0 (95% confidence interval, 3.7-1536.0).
  • CONCLUSION: Obvious hypointensity relative to the cerebral cortex on T1WI was the most valuable magnetic resonance finding in the diagnosis of microcystic meningioma.
  • [MeSH-major] Magnetic Resonance Imaging / methods. Meningeal Neoplasms / diagnosis. Meningioma / diagnosis
  • [MeSH-minor] Adult. Aged. Cerebral Cortex / pathology. Contrast Media / administration & dosage. Diagnosis, Differential. Female. Gadolinium. Humans. Image Enhancement / methods. Male. Middle Aged. Observer Variation. Odds Ratio. Predictive Value of Tests. Retrospective Studies. Sensitivity and Specificity

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  • (PMID = 18303301.001).
  • [ISSN] 0363-8715
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; AU0V1LM3JT / Gadolinium
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42. Ney DE, Huse JT, Dunkel IJ, Steinherz PG, Haque S, Khakoo Y: Intraventricular meningioma after cranial irradiation for childhood leukemia. J Child Neurol; 2010 Oct;25(10):1292-5
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  • [Title] Intraventricular meningioma after cranial irradiation for childhood leukemia.
  • Meningiomas are among the most common brain tumors in adults.
  • The authors describe a case of an intraventricular meningioma occurring 23 years after cranial irradiation for childhood acute lymphoblastic leukemia.
  • [MeSH-major] Cerebral Ventricle Neoplasms / etiology. Cerebral Ventricle Neoplasms / pathology. Meningeal Neoplasms / etiology. Meningeal Neoplasms / pathology. Meningioma / etiology. Meningioma / pathology. Neoplasms, Radiation-Induced / pathology
  • [MeSH-minor] Adult. Child, Preschool. Diagnosis, Differential. Humans. Male. Precursor Cell Lymphoblastic Leukemia-Lymphoma / radiotherapy

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  • (PMID = 20207611.001).
  • [ISSN] 1708-8283
  • [Journal-full-title] Journal of child neurology
  • [ISO-abbreviation] J. Child Neurol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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43. Bethke L, Murray A, Webb E, Schoemaker M, Muir K, McKinney P, Hepworth S, Dimitropoulou P, Lophatananon A, Feychting M, Lönn S, Ahlbom A, Malmer B, Henriksson R, Auvinen A, Kiuru A, Salminen T, Johansen C, Christensen HC, Kosteljanetz M, Swerdlow A, Houlston R: Comprehensive analysis of DNA repair gene variants and risk of meningioma. J Natl Cancer Inst; 2008 Feb 20;100(4):270-6
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  • [Title] Comprehensive analysis of DNA repair gene variants and risk of meningioma.
  • BACKGROUND: Meningiomas account for up to 37% of all primary brain tumors.
  • Genetic susceptibility to meningioma is well established, with the risk among relatives of meningioma patients being approximately threefold higher than that in the general population.
  • A relationship between risk of meningioma and exposure to ionizing radiation is also well known and led us to examine whether variants in DNA repair genes contribute to disease susceptibility.
  • We also analyzed 388 putative functional SNPs in these genes for their association with meningioma.
  • RESULTS: The SNP rs4968451, which maps to intron 4 of the gene that encodes breast cancer susceptibility gene 1-interacting protein 1, was consistently associated with an increased risk of developing meningioma.
  • CONCLUSIONS: We have identified a novel association between rs4968451 and meningioma risk.
  • Because approximately 28% of the European population are carriers of at-risk genotypes for rs4968451, the variant is likely to make a substantial contribution to the development of meningioma.
  • [MeSH-major] DNA Repair / genetics. Meningeal Neoplasms / genetics. Meningioma / genetics. Polymorphism, Single Nucleotide
  • [MeSH-minor] Adult. Aged. Case-Control Studies. Europe. Female. Genetic Predisposition to Disease. Humans. Male. Middle Aged. Odds Ratio. Risk Assessment. Risk Factors

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  • (PMID = 18270339.001).
  • [ISSN] 1460-2105
  • [Journal-full-title] Journal of the National Cancer Institute
  • [ISO-abbreviation] J. Natl. Cancer Inst.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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44. Rajaraman P, Brenner AV, Neta G, Pfeiffer R, Wang SS, Yeager M, Thomas G, Fine HA, Linet MS, Rothman N, Chanock SJ, Inskip PD: Risk of meningioma and common variation in genes related to innate immunity. Cancer Epidemiol Biomarkers Prev; 2010 May;19(5):1356-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Risk of meningioma and common variation in genes related to innate immunity.
  • BACKGROUND: The etiology of meningioma, the second most common type of adult brain tumor in the United States, is largely unknown.
  • Prior studies indicate that history of immune-related conditions may affect the risk of meningioma.
  • METHODS: To identify genetic markers for meningioma in genes involved with innate immunity, we conducted an exploratory association study of 101 meningioma cases and 330 frequency-matched controls of European ancestry using subjects from a hospital-based study conducted by the National Cancer Institute.
  • Risk of meningioma was estimated by odds ratios and 95% confidence intervals.
  • RESULTS: Seventeen SNPs distributed across 12 genetic regions (NFKB1 (3), FCER1G (3), CCR6 (2), VCAM1, CD14, TNFRSF18, RAC2, XDH, C1D, TLR1/TLR10/TLR6, NOS1, and DEFA5) were associated with the risk of meningioma with P<0.01.
  • CONCLUSIONS AND IMPACT: Our results indicate that common genetic polymorphisms in innate immunity genes may be associated with risk of meningioma.
  • Given the small sample size, replication of these results in a larger study of meningioma is needed.

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  • (PMID = 20406964.001).
  • [ISSN] 1538-7755
  • [Journal-full-title] Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
  • [ISO-abbreviation] Cancer Epidemiol. Biomarkers Prev.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / N01CO12400; United States / Intramural NIH HHS / / Z99 CA999999; United States / NCI NIH HHS / CO / N01-CO-12400
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Neoplasm Proteins
  • [Other-IDs] NLM/ NIHMS184299; NLM/ PMC3169167
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45. Gerber DE, Segal JB, Salhotra A, Olivi A, Grossman SA, Streiff MB: Venous thromboembolism occurs infrequently in meningioma patients receiving combined modality prophylaxis. Cancer; 2007 Jan 15;109(2):300-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Venous thromboembolism occurs infrequently in meningioma patients receiving combined modality prophylaxis.
  • BACKGROUND: Individuals with brain tumors have an increased risk of venous thromboembolism (VTE).
  • Within this population, patients with meningiomas have been reported to have the highest incidence, exceeding rates associated with gliomas and brain metastases.
  • Therefore, we conducted a retrospective review of postoperative meningioma patients receiving contemporary VTE prophylaxis and diagnostic methods to define the current incidence of and risk factors for symptomatic VTE in this population.
  • METHODS: Medical records were reviewed from all patients undergoing craniotomy for meningioma at Johns Hopkins Hospital in 2004 and 2005.
  • CONCLUSIONS: VTE occurs infrequently in postoperative meningioma patients who receive combined modality VTE prophylaxis.
  • [MeSH-major] Meningeal Neoplasms / surgery. Meningioma / surgery. Postoperative Complications / etiology. Thromboembolism / etiology. Venous Thrombosis / etiology
  • [MeSH-minor] Adult. Age Factors. Aged. Analysis of Variance. Combined Modality Therapy. Female. Humans. Male. Middle Aged. Retrospective Studies. Risk Factors. Sex Factors. Time Factors


46. Char DH, Shiel MJ: Orbital meningioma after cranial radiation for acute lymphocytic leukemia. Orbit; 2008;27(4):321-3
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  • [Title] Orbital meningioma after cranial radiation for acute lymphocytic leukemia.
  • PURPOSE: To describe the ophthalmic findings of cranial radiation-induced orbital meningioma after acute lymphocytic leukemia therapy.
  • [MeSH-major] Brain Neoplasms / radiotherapy. Cranial Irradiation / adverse effects. Meningeal Neoplasms / etiology. Meningioma / etiology. Neoplasms, Radiation-Induced / etiology. Precursor Cell Lymphoblastic Leukemia-Lymphoma / radiotherapy
  • [MeSH-minor] Adult. Humans. Magnetic Resonance Imaging. Male

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  • (PMID = 18716974.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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47. Malmer BS, Feychting M, Lönn S, Lindström S, Grönberg H, Ahlbom A, Schwartzbaum J, Auvinen A, Collatz-Christensen H, Johansen C, Kiuru A, Mudie N, Salminen T, Schoemaker MJ, Swerdlow AJ, Henriksson R: Genetic variation in p53 and ATM haplotypes and risk of glioma and meningioma. J Neurooncol; 2007 May;82(3):229-37
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  • [Title] Genetic variation in p53 and ATM haplotypes and risk of glioma and meningioma.
  • BACKGROUND: P53 and ATM are central checkpoint genes involved in the repair of DNA damage after ionising irradiation, which has been associated with risk of brain tumours.
  • Therefore, we tested the hypothesis that polymorphisms and haplotypes in p53 and ATM could be associated with glioma and meningioma risk.
  • MATERIAL AND METHODS: Six hundred and eighty glioma cases (298 glioblastoma (GBM)), 503 meningioma cases, and 1555 controls recruited in the Nordic-UK Interphone study, were analysed in association with three polymorphisms in p53 (rs2287499, rs1042533, rs1625895) and five polymorphisms in ATM ( rs228599, rs3092992, rs664143, rs170548, rs3092993).
  • The haplotype analysis in ATM revealed an increased frequency of the 1-1-1-2-1 haplotype in meningioma cases (33.8%) compared with controls (30.3%) (p = 0.03).
  • The 2-1-2-1-1 haplotype had a lower frequency in meningioma cases (36.1%) than controls (40.7%) (p = 0.009).
  • CONCLUSIONS: This study found both positive and negative associations of haplotypes in p53 for glioblastoma and ATM for meningioma.
  • This study provides new data that could add to our understanding of brain tumour susceptibility.
  • [MeSH-major] Brain Neoplasms / genetics. Cell Cycle Proteins / genetics. DNA-Binding Proteins / genetics. Glioma / genetics. Meningeal Neoplasms / genetics. Meningioma / genetics. Protein-Serine-Threonine Kinases / genetics. Tumor Suppressor Protein p53 / genetics. Tumor Suppressor Proteins / genetics
  • [MeSH-minor] Adult. Aged. Ataxia Telangiectasia Mutated Proteins. Case-Control Studies. Female. Genetic Predisposition to Disease. Haplotypes. Humans. Male. Middle Aged. Polymorphism, Single Nucleotide. Risk Factors

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  • (PMID = 17151932.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Cell Cycle Proteins; 0 / DNA-Binding Proteins; 0 / Tumor Suppressor Protein p53; 0 / Tumor Suppressor Proteins; EC 2.7.11.1 / ATM protein, human; EC 2.7.11.1 / Ataxia Telangiectasia Mutated Proteins; EC 2.7.11.1 / Protein-Serine-Threonine Kinases
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48. Tella OI Jr, Paiva Neto MA, Herculano MA, Faedo Neto A: [Olfactory groove meningioma]. Arq Neuropsiquiatr; 2006 Mar;64(1):83-7
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  • [Title] [Olfactory groove meningioma].
  • One patient died on post-operative period due to brain infarction and three patients had cerebrospinal fluid fistula that resolved.
  • [MeSH-major] Meningeal Neoplasms / surgery. Meningioma / surgery
  • [MeSH-minor] Adult. Aged. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Invasiveness. Postoperative Complications. Retrospective Studies. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 16622559.001).
  • [ISSN] 0004-282X
  • [Journal-full-title] Arquivos de neuro-psiquiatria
  • [ISO-abbreviation] Arq Neuropsiquiatr
  • [Language] por
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Brazil
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49. Schwartzbaum J, Jonsson F, Ahlbom A, Preston-Martin S, Malmer B, Lönn S, Söderberg K, Feychting M: Prior hospitalization for epilepsy, diabetes, and stroke and subsequent glioma and meningioma risk. Cancer Epidemiol Biomarkers Prev; 2005 Mar;14(3):643-50
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  • [Title] Prior hospitalization for epilepsy, diabetes, and stroke and subsequent glioma and meningioma risk.
  • We conducted a case-control study to evaluate the preclinical association between epilepsy, diabetes, and stroke and primary adult brain tumors.
  • We first identified all 1,501 low-grade glioma, 4,587 high-grade glioma (HGG), and 4,193 meningioma cases reported to the Swedish Cancer Registry from 1987 to 1999.
  • Results are similar for glioblastoma multiforme, low-grade glioma, and meningioma.
  • In contrast, risk of HGG among people discharged with diabetes or stroke does not increase until year of brain tumor diagnosis.
  • [MeSH-major] Brain Neoplasms / etiology. Diabetes Complications. Diabetes Mellitus / therapy. Epilepsy / complications. Glioma / etiology. Meningeal Neoplasms / etiology. Meningioma / etiology. Stroke / complications
  • [MeSH-minor] Adult. Age of Onset. Aged. Case-Control Studies. Female. Hospitalization. Humans. Male. Middle Aged. Risk Factors. Time Factors


50. Tena-Suck ML, Collado-Ortìz MA, Salinas-Lara C, García-López R, Gelista N, Rembao-Bojorquez D: Chordoid meningioma: a report of ten cases. J Neurooncol; 2010 Aug;99(1):41-8
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  • [Title] Chordoid meningioma: a report of ten cases.
  • Chordoid meningioma is a rare variant of meningioma with histological features resembling those of chordoma.
  • This study was done to document the clinical and pathological features of ten patients with chordoid meningioma who submitted to surgery at the National Institute of Neurology and Neurosurgery in Mexico City.
  • Two of the ten tumors showed metaplasic changes, and seven showed brain invasion.
  • Chordoid meningioma, World Health Organization grade II, is an uncommon variant of meningioma with a propensity for aggressive behavior and increased likelihood of recurrence.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Meningeal Neoplasms / metabolism. Meningeal Neoplasms / pathology. Meningioma / metabolism. Meningioma / pathology
  • [MeSH-minor] Adult. Aged. Antigens, Neoplasm / metabolism. Cell Adhesion Molecules / metabolism. Female. Glial Fibrillary Acidic Protein / metabolism. Humans. Ki-67 Antigen / metabolism. Male. Middle Aged. Mucin-1 / metabolism. Retrospective Studies. S100 Proteins / metabolism. Vimentin / metabolism

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  • (PMID = 20094774.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Cell Adhesion Molecules; 0 / EPCAM protein, human; 0 / Glial Fibrillary Acidic Protein; 0 / Ki-67 Antigen; 0 / Mucin-1; 0 / S100 Proteins; 0 / Vimentin
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51. Tamura Y, Miyatake S, Nonoguchi N, Miyata S, Yokoyama K, Doi A, Kuroiwa T, Asada M, Tanabe H, Ono K: Boron neutron capture therapy for recurrent malignant meningioma. Case report. J Neurosurg; 2006 Dec;105(6):898-903
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  • [Title] Boron neutron capture therapy for recurrent malignant meningioma. Case report.
  • Malignant meningioma is a rare brain tumor with a high risk of recurrence.
  • The authors report the first case of recurrent malignant meningioma treated using boron neutron capture therapy (BNCT).
  • The minimum tumor dose and maximum brain tissue dose were estimated as 39.7 Gy-Eq and less than 9.0 Gy-Eq, respectively.
  • The treatment of recurrent malignant meningioma is difficult and has been discouraging thus far.
  • [MeSH-major] Boron Neutron Capture Therapy. Cranial Irradiation. Meningeal Neoplasms / radiotherapy. Meningioma / radiotherapy. Neoplasm Recurrence, Local / radiotherapy. Pregnancy Complications, Neoplastic / radiotherapy
  • [MeSH-minor] Adult. Combined Modality Therapy. Female. Follow-Up Studies. Humans. Image Processing, Computer-Assisted. Magnetic Resonance Imaging. Neurologic Examination. Positron-Emission Tomography. Pregnancy. Radiosurgery. Radiotherapy Dosage. Radiotherapy, Adjuvant. Reoperation

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  • (PMID = 17405262.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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52. Phillips LE, Frankenfeld CL, Drangsholt M, Koepsell TD, van Belle G, Longstreth WT Jr: Intracranial meningioma and ionizing radiation in medical and occupational settings. Neurology; 2005 Jan 25;64(2):350-2
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  • [Title] Intracranial meningioma and ionizing radiation in medical and occupational settings.
  • In a population-based case-control study of 200 cases and 400 controls in western Washington State, the authors assessed associations between meningioma and ionizing radiation in medical and occupational settings.
  • [MeSH-major] Cranial Irradiation / adverse effects. Meningeal Neoplasms / epidemiology. Meningioma / epidemiology. Neoplasms, Radiation-Induced / epidemiology. Occupational Exposure
  • [MeSH-minor] Adolescent. Adult. Aged. Brain Neoplasms / epidemiology. Brain Neoplasms / etiology. Case-Control Studies. Confidence Intervals. Cross-Sectional Studies. Female. Humans. Male. Middle Aged. Odds Ratio. Risk. Time Factors. Washington / epidemiology

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  • (PMID = 15668439.001).
  • [ISSN] 1526-632X
  • [Journal-full-title] Neurology
  • [ISO-abbreviation] Neurology
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA 60710
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
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53. Tirakotai W, Mennel HD, Celik I, Hellwig D, Bertalanffy H, Riegel T: Secretory meningioma: immunohistochemical findings and evaluation of mast cell infiltration. Neurosurg Rev; 2006 Jan;29(1):41-8
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  • [Title] Secretory meningioma: immunohistochemical findings and evaluation of mast cell infiltration.
  • This study aimed to obtain more information about the immunohistochemical characteristics of this histological entity, and to analyse the effects of histological factors such as the presence of mast cells on the radiological evidence of surrounding tumour oedema that frequently occurred in this subtype of meningioma.
  • Fourteen cases of secretory meningioma were examined.
  • [MeSH-major] Mast Cells / chemistry. Mast Cells / pathology. Meningeal Neoplasms / chemistry. Meningeal Neoplasms / immunology. Meningioma / chemistry. Meningioma / immunology
  • [MeSH-minor] Actins / analysis. Adult. Aged. Brain Edema / epidemiology. Brain Edema / pathology. Carcinoembryonic Antigen / analysis. Cell Movement. Cell Proliferation. Female. Humans. Immunohistochemistry. Incidence. Keratins / analysis. Ki-67 Antigen / analysis. Male. Middle Aged. Mucin-1 / analysis. Pericytes / pathology. Vimentin / analysis

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  • (PMID = 16010579.001).
  • [ISSN] 0344-5607
  • [Journal-full-title] Neurosurgical review
  • [ISO-abbreviation] Neurosurg Rev
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Actins; 0 / Carcinoembryonic Antigen; 0 / Ki-67 Antigen; 0 / Mucin-1; 0 / Vimentin; 68238-35-7 / Keratins
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54. Tawil A, Comair Y, Nasser H, Hourani R, Rebeiz J, Chamoun R: Periosteal osteoblastoma of the calvaria mimicking a meningioma. Pathol Res Pract; 2008;204(6):413-22
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  • [Title] Periosteal osteoblastoma of the calvaria mimicking a meningioma.
  • Magnetic resonance imaging of the brain showed an extra-axial temporal mass with findings that were suggestive of a meningioma.
  • The tumor was strongly positive for epithelial membrane antigen, a feature not previously described in osteoblastoma, and one that could lead to a mistaken diagnosis of metaplastic meningioma in a limited sample.
  • Correlation with the radiological findings is crucial for the diagnosis in most cases; however, it is not helpful in differentiating the rare intracranial periosteal variant from a meningioma.
  • [MeSH-major] Bone Neoplasms / diagnosis. Meningioma / diagnosis. Osteoblastoma / diagnosis. Skull / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Mucin-1 / analysis. Treatment Outcome

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  • (PMID = 18359169.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Mucin-1
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55. Hope AJ, Mansur DB, Tu PH, Simpson JR: Metachronous secondary atypical meningioma and anaplastic astrocytoma after postoperative craniospinal irradiation for medulloblastoma. Childs Nerv Syst; 2006 Sep;22(9):1201-7
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  • [Title] Metachronous secondary atypical meningioma and anaplastic astrocytoma after postoperative craniospinal irradiation for medulloblastoma.
  • INTRODUCTION: Malignant brain tumors have been reported to occur after childhood irradiation more frequently than in the nonirradiated population.
  • DISCUSSION: In this study, we report the case of a 15-year-old boy treated for medulloblastoma with surgery and craniospinal radiotherapy, who developed a meningioma 18 years after initial treatment and subsequently an anaplastic astrocytoma 23 years after primary treatment.
  • The meningioma was resected without complications.
  • [MeSH-major] Astrocytoma / diagnosis. Cerebellar Neoplasms / radiotherapy. Cranial Irradiation / adverse effects. Medulloblastoma / radiotherapy. Meningeal Neoplasms / diagnosis. Meningioma / diagnosis. Neoplasms, Radiation-Induced / diagnosis. Neoplasms, Second Primary / diagnosis
  • [MeSH-minor] Adolescent. Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biopsy. Chemotherapy, Adjuvant. Combined Modality Therapy. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Radiotherapy Dosage. Radiotherapy, Adjuvant. Reoperation. Tomography, X-Ray Computed

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  • (PMID = 16570196.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 40
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56. Takahashi S, Ohira T, Shido S, Kawase T: Focal hand dystonia cured by removal of clinoid meningioma-case report-. Neurol Med Chir (Tokyo); 2009 Dec;49(12):619-21
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  • [Title] Focal hand dystonia cured by removal of clinoid meningioma-case report-.
  • A 40-year-old Asian female presented with an unusual case of focal hand dystonia caused by contralateral clinoid meningioma.
  • Magnetic resonance imaging after surgery showed that the compression of the surrounding brain was released.
  • This case shows that secondary focal hand dystonia caused by extra-axial brain tumor can be cured by surgical removal.
  • [MeSH-major] Dystonic Disorders / etiology. Meningeal Neoplasms / pathology. Meningeal Neoplasms / surgery. Meningioma / pathology. Meningioma / surgery. Skull Base Neoplasms / pathology. Skull Base Neoplasms / surgery
  • [MeSH-minor] Adult. Basal Ganglia / pathology. Basal Ganglia / physiopathology. Basal Ganglia Diseases / etiology. Basal Ganglia Diseases / pathology. Basal Ganglia Diseases / physiopathology. Decompression, Surgical / methods. Disease Progression. Female. Hand / innervation. Hand / physiopathology. Humans. Internal Capsule / pathology. Internal Capsule / physiopathology. Magnetic Resonance Imaging. Neoplasm Invasiveness / pathology. Neural Pathways / pathology. Neural Pathways / physiopathology. Neurosurgical Procedures / methods. Sphenoid Bone / pathology. Sphenoid Bone / surgery. Tegmentum Mesencephali / pathology. Tegmentum Mesencephali / physiopathology. Treatment Outcome

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  • (PMID = 20035142.001).
  • [ISSN] 1349-8029
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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57. Kaynar MY, Sanus GZ, Hnimoglu H, Kacira T, Kemerdere R, Atukeren P, Gumustas K, Canbaz B, Tanriverdi T: Expression of hypoxia inducible factor-1alpha in tumors of patients with glioblastoma multiforme and transitional meningioma. J Clin Neurosci; 2008 Sep;15(9):1036-42
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  • [Title] Expression of hypoxia inducible factor-1alpha in tumors of patients with glioblastoma multiforme and transitional meningioma.
  • The aim of this study was to assess HIF-1alpha in 22 patients with transitional meningioma (TM) and 26 patients with glioblastoma multiforme (GBM).
  • These findings indicate that HIF-1alpha is elevated in both TM and GBM, suggesting that although hypoxia is one of the most important and powerful stimuli for HIF-1alpha elevation and consequently angiogenesis, other mechanisms may play roles in HIF-1alpha stimulation in benign brain tumors such as TM.
  • [MeSH-major] Brain Neoplasms / metabolism. Glioblastoma / metabolism. Hypoxia-Inducible Factor 1, alpha Subunit / metabolism. Meningeal Neoplasms / metabolism. Meningioma / metabolism
  • [MeSH-minor] Adult. Aged. Anoxia / diagnosis. Anoxia / metabolism. Anoxia / physiopathology. Biomarkers, Tumor / analysis. Biomarkers, Tumor / metabolism. Cell Hypoxia / physiology. Enzyme-Linked Immunosorbent Assay. Female. Humans. Male. Middle Aged. Neovascularization, Pathologic / etiology. Neovascularization, Pathologic / metabolism. Neovascularization, Pathologic / physiopathology. Predictive Value of Tests. Up-Regulation / physiology

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  • (PMID = 18621534.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / HIF1A protein, human; 0 / Hypoxia-Inducible Factor 1, alpha Subunit
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58. Bruna J, Brell M, Ferrer I, Gimenez-Bonafe P, Tortosa A: Ki-67 proliferative index predicts clinical outcome in patients with atypical or anaplastic meningioma. Neuropathology; 2007 Apr;27(2):114-20
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  • [Title] Ki-67 proliferative index predicts clinical outcome in patients with atypical or anaplastic meningioma.
  • Meningiomas represent the second most common central nervous system neoplasms in adults and account for 26% of all primary brain tumors.
  • Although histological grade is the most relevant prognostic factor, there are some unusual cases in which establishing a diagnosis of high-grade meningioma following 2000 World Health Organization (WHO) histological criteria is extremely difficult.
  • More importantly, this predictive value was maintained in both patients with atypical and patients with anaplastic meningioma.
  • [MeSH-major] Biomarkers, Tumor / analysis. Ki-67 Antigen / metabolism. Meningeal Neoplasms / pathology. Meningioma / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Cell Proliferation. Female. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Recurrence, Local / pathology. Prognosis. ROC Curve. Sensitivity and Specificity. Survival Analysis

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  • [CommentIn] Neuropathology. 2008 Feb;28(1):106-7 [18181839.001]
  • (PMID = 17494511.001).
  • [ISSN] 0919-6544
  • [Journal-full-title] Neuropathology : official journal of the Japanese Society of Neuropathology
  • [ISO-abbreviation] Neuropathology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen
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59. Bacciu A, Piazza P, Di Lella F, Sanna M: Intracanalicular meningioma: clinical features, radiologic findings, and surgical management. Otol Neurotol; 2007 Apr;28(3):391-9
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  • [Title] Intracanalicular meningioma: clinical features, radiologic findings, and surgical management.
  • PATIENTS: Thirteen consecutive patients with pathologically confirmed intracanalicular meningioma surgically treated between December 1988 and July 2006.
  • On account of a lack of specific symptoms and the limited diagnostic findings, preoperative diagnosis of intracanalicular meningioma still represents a diagnostic challenge.
  • [MeSH-major] Ear Neoplasms / pathology. Ear Neoplasms / surgery. Meningeal Neoplasms / pathology. Meningeal Neoplasms / surgery. Meningioma / pathology. Meningioma / surgery. Otologic Surgical Procedures / methods. Vestibular Aqueduct / pathology. Vestibular Aqueduct / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Audiometry, Pure-Tone. Evoked Potentials, Auditory, Brain Stem. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Postoperative Complications / diagnosis. Postoperative Complications / epidemiology. Retrospective Studies

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  • (PMID = 17287658.001).
  • [ISSN] 1531-7129
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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60. Andersson U, Osterman P, Sjöström S, Johansen C, Henriksson R, Brännström T, Broholm H, Christensen HC, Ahlbom A, Auvinen A, Feychting M, Lönn S, Kiuru A, Swerdlow A, Schoemaker M, Roos G, Malmer B: MNS16A minisatellite genotypes in relation to risk of glioma and meningioma and to glioblastoma outcome. Int J Cancer; 2009 Aug 15;125(4):968-72
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  • [Title] MNS16A minisatellite genotypes in relation to risk of glioma and meningioma and to glioblastoma outcome.
  • Published data on the clinical relevance of MNS16A variants in brain tumours have been contradictory.
  • The present population-based study in the Nordic countries and the United Kingdom evaluated brain-tumour risk and survival in relation to MNS16A minisatellite variants in 648 glioma cases, 473 meningioma cases and 1,359 age, sex and geographically matched controls.
  • Relative risk of glioma or meningioma was estimated with logistic regression adjusting for age, sex and country.
  • The MNS16A genotype was not associated with risk of occurrence of glioma, glioblastoma (GBM) or meningioma.
  • [MeSH-major] Glioblastoma / genetics. Meningeal Neoplasms / genetics. Meningioma / genetics. Minisatellite Repeats / genetics
  • [MeSH-minor] Adult. Aged. Case-Control Studies. Female. Genotype. Great Britain. Humans. Male. Middle Aged. Prognosis. Telomerase / genetics. Treatment Outcome. Young Adult

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  • (PMID = 19405125.001).
  • [ISSN] 1097-0215
  • [Journal-full-title] International journal of cancer
  • [ISO-abbreviation] Int. J. Cancer
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] EC 2.7.7.49 / TERT protein, human; EC 2.7.7.49 / Telomerase
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61. Lah TT, Nanni I, Trinkaus M, Metellus P, Dussert C, De Ridder L, Rajcević U, Blejec A, Martin PM: Toward understanding recurrent meningioma: the potential role of lysosomal cysteine proteases and their inhibitors. J Neurosurg; 2010 May;112(5):940-50
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  • [Title] Toward understanding recurrent meningioma: the potential role of lysosomal cysteine proteases and their inhibitors.
  • The second aim was to confirm if cathepsin B and/or cathepsin L and their endogenous inhibitors were also prognostic parameters in the clinical study of 119 patients with meningioma.
  • METHODS: Primary meningioma cultured spheroids were "confronted" with embryonic chick heart spheroids in vitro, and cathepsin B was used as molecular marker to immunolabel the invasive tumor cells.
  • In vitro invasion assays of the malignant meningioma cells were used to assess the invasive potential related to the cysteine cathepsins.
  • As to the second aim, the possible association of cathepsin B along with selected molecular markers, cathepsin L, and endogenous cysteine protease inhibitors (stefins A and B and cystatin C) with meningioma malignancy was determined using enzyme-linked immunosorbent assays in tumor homogenates.
  • Univariate and multivariate analyses were used to compare these parameters with established biological markers of meningioma recurrence in 119 patients with meningiomas.
  • Matrigel invasion of malignant meningioma cells was significantly altered by modulating cathepsin B activity and by stefin B silencing.
  • In the clinical samples of meningioma, the levels of cathepsins B and L, stefin B, and cystatin C were highest in the tumors of higher histological grades, whereas stefin A and progesterone receptor were the only markers that were significantly increased and decreased, respectively, in WHO Grade III lesions.
  • CONCLUSIONS: The data indicate that the cysteine cathepsins and their inhibitors are involved in a process related to early meningioma recurrence, regardless of their histological classification.
  • Of note, the known tumor invasiveness marker cathepsin B, measured in whole-tumor homogenates, was not prognostic, in contrast to its endogenous inhibitor stefin B, which was highly significant and the only independent prognostic factor to predict meningioma relapse in multivariate analysis and reported herein for the first time.
  • [MeSH-major] Brain Neoplasms / drug therapy. Brain Neoplasms / pathology. Cysteine Proteinase Inhibitors / pharmacology. Cysteine Proteinase Inhibitors / therapeutic use. Lysosomes / drug effects. Meningioma / drug therapy. Meningioma / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Cathepsin B / genetics. Cystatin A / genetics. Cystatin B / genetics. Female. Gene Silencing. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Neoplasm Staging. Neurosurgical Procedures. World Health Organization. Young Adult

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  • (PMID = 19747051.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CSTB protein, human; 0 / Cystatin A; 0 / Cysteine Proteinase Inhibitors; 88844-95-5 / Cystatin B; EC 3.4.22.1 / CTSB protein, human; EC 3.4.22.1 / Cathepsin B
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62. Schüz J, Böhler E, Berg G, Schlehofer B, Hettinger I, Schlaefer K, Wahrendorf J, Kunna-Grass K, Blettner M: Cellular phones, cordless phones, and the risks of glioma and meningioma (Interphone Study Group, Germany). Am J Epidemiol; 2006 Mar 15;163(6):512-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cellular phones, cordless phones, and the risks of glioma and meningioma (Interphone Study Group, Germany).
  • The widespread use of cellular telephones has generated concern about possible adverse health effects, particularly brain tumors.
  • In this population-based case-control study carried out in three regions of Germany, all incident cases of glioma and meningioma among patients aged 30-69 years were ascertained during 2000-2003.
  • In total, 366 glioma cases, 381 meningioma cases, and 1,494 controls were interviewed.
  • Overall use of a cellular phone was not associated with brain tumor risk; the respective odds ratios were 0.98 (95% confidence interval (CI): 0.74, 1.29) for glioma and 0.84 (95% CI: 0.62, 1.13) for meningioma.
  • Among persons who had used cellular phones for 10 or more years, increased risk was found for glioma (odds ratio = 2.20, 95% CI: 0.94, 5.11) but not for meningioma (odds ratio = 1.09, 95% CI: 0.35, 3.37).
  • No excess of temporal glioma (p = 0.41) or meningioma (p = 0.43) was observed in cellular phone users as compared with nonusers.
  • Cordless phone use was not related to either glioma risk or meningioma risk.
  • In conclusion, no overall increased risk of glioma or meningioma was observed among these cellular phone users; however, for long-term cellular phone users, results need to be confirmed before firm conclusions can be drawn.
  • [MeSH-major] Brain Neoplasms / epidemiology. Cell Phones. Electromagnetic Fields / adverse effects. Glioma / epidemiology. Meningioma / epidemiology
  • [MeSH-minor] Adult. Aged. Case-Control Studies. Environmental Exposure / adverse effects. Female. Germany / epidemiology. Humans. Incidence. Interviews as Topic. Male. Middle Aged. Registries. Risk Assessment. Risk Factors


63. Paiva Neto MA, Tella OI Jr, Herculano MA, Stávale JN, Bonatteli AP: [Olfactory groove meningioma: correlation between clinicoradiological features and proliferative index (Mib-1)]. Arq Neuropsiquiatr; 2006 Mar;64(1):77-82
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  • [Title] [Olfactory groove meningioma: correlation between clinicoradiological features and proliferative index (Mib-1)].
  • METHOD: There were analysed demographic, clinical and radiological features of 15 patients with olfactory groove meningioma.
  • [MeSH-major] Ki-67 Antigen / metabolism. Meningeal Neoplasms / pathology. Meningioma / pathology. Meningioma / radiography. Neoplasm Proteins / metabolism. Neoplasm Recurrence, Local / pathology
  • [MeSH-minor] Adult. Aged. Antibodies, Monoclonal / analysis. Brain Edema / pathology. Brain Edema / radiography. Cell Division / physiology. Female. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging. Retrospective Studies. Tomography, X-Ray Computed

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  • (PMID = 16622558.001).
  • [ISSN] 0004-282X
  • [Journal-full-title] Arquivos de neuro-psiquiatria
  • [ISO-abbreviation] Arq Neuropsiquiatr
  • [Language] por
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Brazil
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Ki-67 Antigen; 0 / Neoplasm Proteins
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64. Armstrong L, Graham GE, Schimke RN, Collins DL, Kirse DJ, Costello F, Ardinger HH: The Hunter-MacDonald syndrome with expanded phenotype including risk of meningioma: an update and review. Am J Med Genet A; 2008 Jan 1;146A(1):83-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The Hunter-MacDonald syndrome with expanded phenotype including risk of meningioma: an update and review.
  • Decreased hearing acuity, transient cranial nerve palsies, congenital heart defects, and meningioma are also reported.
  • Herein, we present two cases, and, through review of the manifestations of HMS in affected and at-risk family members, we have observed that predisposition to brain tumor is a cardinal feature of this condition.
  • [MeSH-major] Abnormalities, Multiple / genetics. Meningeal Neoplasms / genetics. Meningioma / genetics. Phenotype
  • [MeSH-minor] Adult. Child. Female. Genes, Dominant. Hearing Loss / genetics. Hearing Loss / physiopathology. Humans. Male. Pedigree. Risk Factors. Syndrome

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  • [Copyright] (c) 2007 Wiley-Liss, Inc.
  • (PMID = 17972300.001).
  • [ISSN] 1552-4833
  • [Journal-full-title] American journal of medical genetics. Part A
  • [ISO-abbreviation] Am. J. Med. Genet. A
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 17
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65. Cassereau J, Lavigne C, Michalak-Provost S, Ghali A, Dubas F, Fournier HD: An intraventricular clear cell meningioma revealed by an inflammatory syndrome in a male adult: a case report. Clin Neurol Neurosurg; 2008 Jul;110(7):743-6
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  • [Title] An intraventricular clear cell meningioma revealed by an inflammatory syndrome in a male adult: a case report.
  • Clinical symptoms are mainly due to an increased intracranial pressure or a direct pressure on the surrounding brain structures.
  • Here we report a case of right intraventricular clear cell meningioma in a 50-year-old man who presented with fever, headache, and inflammatory syndrome.
  • To our knowledge, this is the first case described in the literature concerning an adult man with an intraventricular clear cell meningioma associated with a systemic inflammatory syndrome.
  • [MeSH-major] Inflammation / pathology. Meningeal Neoplasms / diagnosis. Meningioma / diagnosis

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  • (PMID = 18514392.001).
  • [ISSN] 0303-8467
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Interleukin-6
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66. Young JP, Young PH: Meningioma associated with abscess formation--a case report. Surg Neurol; 2005 Jun;63(6):584-5
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  • [Title] Meningioma associated with abscess formation--a case report.
  • A rare case of meningioma associated with both intratumoral and peritumoral abscess formation occurred in a 38-year-old man presenting with signs and symptoms of elevated intracranial pressure, intracranial infection, and right temporal pole mass lesion.
  • The mass lesion was totally removed, revealing a meningioma.
  • [MeSH-major] Brain Abscess / microbiology. Brain Abscess / pathology. Meningeal Neoplasms / complications. Meningeal Neoplasms / pathology. Meningioma / complications. Meningioma / pathology
  • [MeSH-minor] Adult. Dental Instruments / adverse effects. Dura Mater / pathology. Humans. Male. Neurosurgical Procedures. Oxacillin / therapeutic use. Sphenoid Bone / pathology. Streptococcal Infections / complications. Streptococcal Infections / etiology. Streptococcal Infections / physiopathology. Temporal Lobe / pathology. Treatment Outcome

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  • (PMID = 15936397.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] UH95VD7V76 / Oxacillin
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67. Fu JY, Gao XG, Li SY, Wang LZ, Hu YJ: [Ectopic meningioma in oral and maxillofacial region: report of 23 cases]. Shanghai Kou Qiang Yi Xue; 2010 Feb;19(1):23-7
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  • [Title] [Ectopic meningioma in oral and maxillofacial region: report of 23 cases].
  • PURPOSE: To analyse the clinical features and treatment of ectopic meningioma (EM) in oral and maxillofacial region.
  • The CT image of EM in the oral and maxillofacial region was similar to that in the brain.
  • [MeSH-major] Meningioma. Mouth Neoplasms. Tomography, X-Ray Computed
  • [MeSH-minor] Adult. Female. Humans. Male. Meningeal Neoplasms. Retrospective Studies

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  • (PMID = 20300688.001).
  • [ISSN] 1006-7248
  • [Journal-full-title] Shanghai kou qiang yi xue = Shanghai journal of stomatology
  • [ISO-abbreviation] Shanghai Kou Qiang Yi Xue
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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68. Epstein NE, Drexler S, Schneider J: Clear cell meningioma of the cauda equina in an adult: case report and literature review. J Spinal Disord Tech; 2005 Dec;18(6):539-43
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  • [Title] Clear cell meningioma of the cauda equina in an adult: case report and literature review.
  • Preoperative noncontrast MR studies of the brain and cervical and thoracic spine were negative.
  • Differential diagnoses included meningioma versus renal cell carcinoma.
  • [MeSH-major] Cauda Equina / pathology. Cauda Equina / surgery. Meningioma / diagnosis. Meningioma / surgery. Peripheral Nervous System Neoplasms / diagnosis. Peripheral Nervous System Neoplasms / surgery
  • [MeSH-minor] Adult. Female. Humans. Paresis / diagnosis. Paresis / etiology. Treatment Outcome

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  • (PMID = 16306847.001).
  • [ISSN] 1536-0652
  • [Journal-full-title] Journal of spinal disorders & techniques
  • [ISO-abbreviation] J Spinal Disord Tech
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 10
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69. Sanai N, Sughrue ME, Shangari G, Chung K, Berger MS, McDermott MW: Risk profile associated with convexity meningioma resection in the modern neurosurgical era. J Neurosurg; 2010 May;112(5):913-9
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  • [Title] Risk profile associated with convexity meningioma resection in the modern neurosurgical era.
  • RESULTS: Between 1997 and 2007, 141 consecutive patients (median age 48 years, range 18-95 years) underwent resection of a supratentorial convexity meningioma.
  • [MeSH-major] Meningioma / pathology. Meningioma / surgery. Neurosurgical Procedures / methods. Radiosurgery / methods. Supratentorial Neoplasms / pathology. Supratentorial Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Female. Humans. Intraoperative Complications / epidemiology. Intraoperative Complications / prevention & control. Male. Microsurgery / instrumentation. Middle Aged. Risk Assessment. Risk Factors. Young Adult

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  • (PMID = 19645533.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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70. Boviatsis EJ, Bouras TI, Kouyialis AT, Themistocleous MS, Sakas DE: Impact of age on complications and outcome in meningioma surgery. Surg Neurol; 2007 Oct;68(4):407-11; discussion 411
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  • [Title] Impact of age on complications and outcome in meningioma surgery.
  • BACKGROUND: Surgery for benign brain tumors in elderly patients without severe general health problems is an acceptable practice, as results are comparable with the ones of younger patients.
  • Regarding each complication, postoperative hematoma, infections, and deep vein thrombosis were more frequent in elderly patients, presenting various degrees of statistical significance, whereas postoperative brain edema, hydrocephalus, and cardiorespiratory incidents presented no statistically significant difference.
  • CONCLUSIONS: Operation for intracranial meningioma in elderly patients is justified as long as detailed preoperative evaluation is performed.
  • [MeSH-major] Meningioma / surgery. Postoperative Complications / epidemiology. Supratentorial Neoplasms / surgery
  • [MeSH-minor] Adult. Age Factors. Aged. Aged, 80 and over. Cerebral Hemorrhage / etiology. Craniotomy. Female. Follow-Up Studies. Humans. Male. Middle Aged. Nervous System Diseases / epidemiology. Neurosurgical Procedures. Retrospective Studies. Treatment Outcome

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  • (PMID = 17586023.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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71. Castellino G, Rizzo N, Bernardi S, Trotta F, Govoni M: Meningioma and systemic lupus erythematosus: a matter of pure coincidence? Lupus; 2009 Jun;18(7):650-4
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  • [Title] Meningioma and systemic lupus erythematosus: a matter of pure coincidence?
  • To describe three cases of meningioma observed in a large cohort of 546 patients with systemic lupus erythematosus (SLE) followed at our Department in the last 15 years.
  • We identified three cases of meningioma among 181 patients with SLE who underwent a brain magnetic resonance imaging (MRI) during their disease course (prevalence 1.65%).
  • All patients presented neuropsychiatric (NP) symptoms and had an incidental finding of a meningioma at brain MRI.
  • The association between meningioma and SLE may be a pure coincidence.
  • [MeSH-major] Lupus Erythematosus, Systemic / complications. Lupus Erythematosus, Systemic / diagnosis. Meningeal Neoplasms / complications. Meningeal Neoplasms / diagnosis. Meningioma / complications. Meningioma / diagnosis
  • [MeSH-minor] Adult. Brain / pathology. Female. Humans. Incidental Findings. Lupus Vasculitis, Central Nervous System / diagnosis. Magnetic Resonance Imaging. Middle Aged


72. Kashimura H, Ogasawara K, Arai H, Beppu T, Inoue T, Takahashi T, Matsuda K, Takahashi Y, Fujiwara S, Ogawa A: Fusion of magnetic resonance angiography and magnetic resonance imaging for surgical planning for meningioma--technical note. Neurol Med Chir (Tokyo); 2008 Sep;48(9):418-21; discussion 422
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  • [Title] Fusion of magnetic resonance angiography and magnetic resonance imaging for surgical planning for meningioma--technical note.
  • A fusion technique for magnetic resonance (MR) angiography and MR imaging was developed to help assess the peritumoral angioarchitecture during surgical planning for meningioma.
  • Three-dimensional time-of-flight (3D-TOF) and 3D-spoiled gradient recalled (SPGR) datasets were obtained from 10 patients with intracranial meningioma, and fused using newly developed volume registration and visualization software.
  • Fusion of MR angiography and MR imaging can clarify relationships between the intracranial vasculature and meningioma, and may be helpful for surgical planning for meningioma.
  • [MeSH-major] Brain Neoplasms / surgery. Magnetic Resonance Angiography / methods. Magnetic Resonance Imaging / methods. Meningioma / surgery. Surgery, Computer-Assisted / methods
  • [MeSH-minor] Adult. Aged. Female. Humans. Male. Middle Aged. Patient Care Planning. Software

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  • (PMID = 18812687.001).
  • [ISSN] 1349-8029
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
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73. Monleón D, Morales JM, Gonzalez-Darder J, Talamantes F, Cortés O, Gil-Benso R, López-Ginés C, Cerdá-Nicolás M, Celda B: Benign and atypical meningioma metabolic signatures by high-resolution magic-angle spinning molecular profiling. J Proteome Res; 2008 Jul;7(7):2882-8
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  • [Title] Benign and atypical meningioma metabolic signatures by high-resolution magic-angle spinning molecular profiling.
  • Meningiomas are neoplasms that arise from the leptomeningeal covering of the brain and spinal cord, accounting for 15%-20% of CNS tumors.
  • Sometimes, meningiomas with histological diagnosis of benign meningioma show clinical characteristics of atypical meningioma.
  • In this context, high-resolution magic-angle spinning (HR-MAS) spectroscopy of intact tissue from brain tumor biopsies has shown great potential as a support diagnostic tool.
  • In this work, we show differences between benign and atypical meningiomas in HR-MAS molecular profiles of meningioma biopsies.
  • Metabolic differences between meningioma grades include changes in the levels of glutathione.
  • [MeSH-major] Meningeal Neoplasms / metabolism. Meningioma / metabolism
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / metabolism. Female. Gene Expression Profiling. Humans. Magnetic Resonance Spectroscopy. Male. Middle Aged. Principal Component Analysis

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  • (PMID = 18507434.001).
  • [ISSN] 1535-3893
  • [Journal-full-title] Journal of proteome research
  • [ISO-abbreviation] J. Proteome Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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74. Drevelegas A, Xinou E, Karacostas D, Parissis D, Karkavelas G, Milonas I: Meningioma growth and interferon beta-1b treated multiple sclerosis: coincidence or relationship? Neuroradiology; 2005 Jul;47(7):516-9
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  • [Title] Meningioma growth and interferon beta-1b treated multiple sclerosis: coincidence or relationship?
  • Although the coincidence of multiple sclerosis (MS) and central nervous system (CNS) tumors has been reported in over 30 cases in English literature, meningioma growth was associated with interferon-beta (INF-b) treated MS only in two of them.
  • We report the case of a 19-year-old woman with clinically possible, laboratory supported MS, and a concomitant right intraventricular tumor with magnetic resonance imaging (MRI) characteristics consistent with meningioma (similar signal with grey matter on T1 and T2-weighted images and homogenous, intense enhancement).
  • Two years after initiation of INF-b treatment, follow-up brain MRI revealed enlargement of the intraventricular mass and relative increase in the number of white matter lesions without significant clinical deterioration.
  • She underwent almost total resection of the mass and histology confirmed the diagnosis of papillary meningioma.
  • Based on the immunohistochemistry results, we speculate that INF-b resulted in meningioma growth by enhancing platelet derived growth factor (PDGF) receptors or/and down-regulating transforming growth factor receptors on the tumor itself.
  • [MeSH-major] Adjuvants, Immunologic / adverse effects. Cerebral Ventricle Neoplasms / diagnosis. Interferon-beta / adverse effects. Magnetic Resonance Imaging. Meningeal Neoplasms / diagnosis. Meningioma / diagnosis. Multiple Sclerosis / drug therapy
  • [MeSH-minor] Adult. Female. Humans. Immunohistochemistry. Interferon beta-1b. Receptors, Platelet-Derived Growth Factor / metabolism

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  • (PMID = 15981002.001).
  • [ISSN] 0028-3940
  • [Journal-full-title] Neuroradiology
  • [ISO-abbreviation] Neuroradiology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Adjuvants, Immunologic; 145155-23-3 / Interferon beta-1b; 77238-31-4 / Interferon-beta; EC 2.7.10.1 / Receptors, Platelet-Derived Growth Factor
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75. Martínez C, Molina JA, Alonso-Navarro H, Jiménez-Jiménez FJ, Agúndez JA, García-Martín E: Two common nonsynonymous paraoxonase 1 (PON1) gene polymorphisms and brain astrocytoma and meningioma. BMC Neurol; 2010;10:71
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  • [Title] Two common nonsynonymous paraoxonase 1 (PON1) gene polymorphisms and brain astrocytoma and meningioma.
  • Aiming to identify genetic variations related to the risk of developing brain tumors, we investigated the putative association between common nonsynonymous PON1 polymorphisms and the risk of developing astrocytoma and meningioma.
  • METHODS: Seventy one consecutive patients with brain tumors (43 with astrocytoma grade II/III and 28 with meningioma) with ages ranging 21 to 76 years, and 220 healthy controls subjects were analyzed for the frequency of the nonsynonymous PON1 genotypes L55M rs854560 and Q192R rs662.
  • All participants were adult Caucasian individuals recruited in the central area of Spain.
  • RESULTS: The frequencies of the PON1 genotypes and allelic variants of the polymorphisms PON1 L55M and PON1 Q192R did not differ significantly between patients with astrocytoma and meningioma and controls.
  • The minor allele frequencies were as follows: PON1 55L, 0.398, 0.328 and 0.286 for patients with astrocytoma, meningioma and control individuals, respectively; PON1 192R, 0.341, 0.362 and 0.302 for patients with astrocytoma, meningioma and control individuals, respectively.
  • Haplotype association analyses did not identify any significant association with the risk of developing astrocytoma or meningioma.
  • CONCLUSIONS: Common nonsynonymous PON1 polymorphisms are not related with the risk of developing astrocytoma and meningioma.
  • [MeSH-major] Aryldialkylphosphatase / genetics. Astrocytoma / genetics. Brain Neoplasms / genetics. Meningeal Neoplasms / genetics. Meningioma / genetics
  • [MeSH-minor] Adult. Aged. Female. Genetic Predisposition to Disease. Genotype. Humans. Male. Middle Aged. Polymerase Chain Reaction. Polymorphism, Single Nucleotide. Young Adult

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  • (PMID = 20723250.001).
  • [ISSN] 1471-2377
  • [Journal-full-title] BMC neurology
  • [ISO-abbreviation] BMC Neurol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] EC 3.1.8.1 / Aryldialkylphosphatase; EC 3.1.8.1 / PON1 protein, human
  • [Other-IDs] NLM/ PMC2936881
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76. Marton E, Bonaldi L, Busato S, Longatti P: Atypical meningioma in Werner syndrome: a case report. J Neurooncol; 2006 Sep;79(2):181-5
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  • [Title] Atypical meningioma in Werner syndrome: a case report.
  • INTRODUCTION: Werner Syndrome, or adult progeria, is a rare autosomal recessive disorder caused by a mutation in the Werner Syndrome Gene belonging to the family of RecQ helicase.
  • CLINICAL PRESENTATION: We present the case of a 46-year-old man with Werner Syndrome and a convexity meningioma.
  • Histological examination revealed an atypical meningioma.
  • CONCLUSION: 1p deletion correlates with meningioma progression and in this case correlates with histological examination.
  • [MeSH-major] Brain Neoplasms / complications. Chromosomes, Human, Pair 22 / genetics. Meningioma / complications. Monosomy / diagnosis. Werner Syndrome / complications

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  • (PMID = 16598422.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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77. Curry WT, McDermott MW, Carter BS, Barker FG 2nd: Craniotomy for meningioma in the United States between 1988 and 2000: decreasing rate of mortality and the effect of provider caseload. J Neurosurg; 2005 Jun;102(6):977-86
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Craniotomy for meningioma in the United States between 1988 and 2000: decreasing rate of mortality and the effect of provider caseload.
  • Multivariate analyses revealed that larger-volume centers had lower mortality rates for patients who underwent craniotomy for meningioma (odds ratio [OR] 0.74, 95% confidence interval [CI] 0.59-0.93, p = 0.01).
  • The annual meningioma caseload in the US increased 83% between 1988 and 2000, from 3900 patients/year to 7200 patients/year.
  • Fewer centers hosted one meningioma resection annually, whereas the largest centers had disproportionate increases in their caseloads, indicating a modest centralization of meningioma surgery in the US during this interval.
  • CONCLUSIONS: The mortality and adverse hospital discharge disposition rates were lower when meningioma surgery was performed by high-volume providers.
  • [MeSH-major] Craniotomy / mortality. Meningeal Neoplasms / mortality. Meningeal Neoplasms / surgery. Meningioma / mortality. Meningioma / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Centralized Hospital Services / statistics & numerical data. Cohort Studies. Databases, Factual. Female. Hospital Mortality / trends. Humans. Male. Middle Aged. Multivariate Analysis. Neurosurgery / statistics & numerical data. Postoperative Complications / mortality. Retrospective Studies. Risk Factors. United States / epidemiology

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  • [CommentIn] J Neurosurg. 2005 Jun;102(6):969-70; discussion 970 [16028752.001]
  • (PMID = 16028755.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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78. Ghosal N, Murthy G, Visvanathan K, Sridhar M, Hegde AS: Isolated intracranial Rosai Dorfman disease masquerading as meningioma: a case report. Indian J Pathol Microbiol; 2007 Apr;50(2):382-4
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  • [Title] Isolated intracranial Rosai Dorfman disease masquerading as meningioma: a case report.
  • Clinically and radiologically patient was diagnosed to have a right parietal convexity meningioma.
  • [MeSH-major] Brain Diseases / pathology. Histiocytosis, Sinus / pathology. Meningeal Neoplasms / diagnosis. Meningioma / diagnosis
  • [MeSH-minor] Adult. Antigens, CD / metabolism. Antigens, Differentiation, Myelomonocytic / metabolism. Diagnosis, Differential. Humans. Male. Parietal Lobe / metabolism. Parietal Lobe / pathology. S100 Proteins / metabolism

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  • (PMID = 17883083.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD68 antigen, human; 0 / S100 Proteins
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79. Singleton RH, Kellermier H, Lunsford LD: Radiation-induced meningioma concealed by shunt valve artifact: case report. Neurosurgery; 2008 Mar;62(3):E743-4; discussion E743-4
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  • [Title] Radiation-induced meningioma concealed by shunt valve artifact: case report.
  • We present the case of a radiation-induced meningioma growing around a ventricular catheter that was not noted at an early stage as a result of artifact from an overlying shunt.
  • Her most recent imaging revealed a new meningioma at the edge of the MRI artifact associated with the shunt valve.
  • A contrasted computed tomographic scan demonstrated a large meningioma with mass effect on the surrounding brain.
  • INTERVENTION: Complete surgical resection of the meningioma was obtained.
  • [MeSH-major] Artifacts. Cerebrospinal Fluid Shunts. Magnetic Resonance Imaging / methods. Meningeal Neoplasms / diagnosis. Meningeal Neoplasms / etiology. Meningioma / diagnosis. Meningioma / etiology. Neoplasms, Radiation-Induced / diagnosis
  • [MeSH-minor] Adult. Female. Humans. Radiotherapy / adverse effects

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  • (PMID = 18424999.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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80. Lind CR, Muthiah K, Bok AP: Peritumoral Citrobacter koseri abscess associated with parasagittal meningioma. Neurosurgery; 2005 Oct;57(4):E814
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  • [Title] Peritumoral Citrobacter koseri abscess associated with parasagittal meningioma.
  • OBJECTIVE AND IMPORTANCE: This is the second report of a Citrobacter-associated brain abscess in an adult and the first report of its association with an intradural tumor.
  • [MeSH-major] Brain Abscess / etiology. Brain Abscess / surgery. Citrobacter koseri. Enterobacteriaceae Infections / surgery. Meningeal Neoplasms / surgery. Meningioma / surgery

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  • (PMID = 17152669.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Thienamycins; 75J73V1629 / Ceftriaxone; FV9J3JU8B1 / meropenem
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81. Phillips LE, Longstreth WT Jr, Koepsell T, Custer BS, Kukull WA, van Belle G: Active and passive cigarette smoking and risk of intracranial meningioma. Neuroepidemiology; 2005;24(3):117-22
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  • [Title] Active and passive cigarette smoking and risk of intracranial meningioma.
  • Motivated by prior studies, we examined associations between cigarette smoking and risk of intracranial meningioma in a population-based case-control study, including 200 cases and 2 controls matched to each case on age and sex.
  • Subjects were asked to recall their history of active and passive cigarette smoking occurring 10 or more years before the date of meningioma surgery.
  • Ever active smoking was associated with an increased risk of meningioma in men (OR = 2.1; 95% CI 1.1-4.2) but not in women (OR = 0.7; 95% CI 0.5-1.1).
  • [MeSH-major] Brain Neoplasms / etiology. Meningeal Neoplasms / etiology. Meningioma / etiology. Smoking / adverse effects. Tobacco Smoke Pollution / adverse effects
  • [MeSH-minor] Adolescent. Adult. Aged. Case-Control Studies. Epidemiologic Studies. Female. Humans. Male. Middle Aged. Odds Ratio. Risk Factors. Sex Factors

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  • [Copyright] Copyright (c) 2005 S. Karger AG, Basel.
  • (PMID = 15637448.001).
  • [ISSN] 0251-5350
  • [Journal-full-title] Neuroepidemiology
  • [ISO-abbreviation] Neuroepidemiology
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA 60710
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Tobacco Smoke Pollution
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82. Hardell L, Carlberg M, Hansson Mild K: Case-control study on cellular and cordless telephones and the risk for acoustic neuroma or meningioma in patients diagnosed 2000-2003. Neuroepidemiology; 2005;25(3):120-8
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  • [Title] Case-control study on cellular and cordless telephones and the risk for acoustic neuroma or meningioma in patients diagnosed 2000-2003.
  • We performed a case-control study on the use of cellular and cordless telephones and the risk for brain tumors.
  • We report the results for benign brain tumors with data from 413 cases (89% response rate), 305 with meningioma, 84 with acoustic neuroma, 24 with other types and 692 controls (84% response rate).
  • For meningioma, analogue phones yielded odds ratio (OR) = 1.7, 95% confidence interval (CI) = 0.97-3.0, increasing to OR = 2.1, 95% CI = 1.1-4.3 with a >10-year latency period.
  • [MeSH-major] Cell Phones / utilization. Meningeal Neoplasms / etiology. Meningioma / etiology. Neuroma, Acoustic / etiology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Case-Control Studies. Female. Humans. Male. Middle Aged. Risk Assessment. Sweden

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  • [Copyright] Copyright 2005 S. Karger AG, Basel.
  • (PMID = 15956809.001).
  • [ISSN] 0251-5350
  • [Journal-full-title] Neuroepidemiology
  • [ISO-abbreviation] Neuroepidemiology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
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83. Fukushima S, Terasaki M, Sakata K, Miyagi N, Kato S, Sugita Y, Shigemori M: Sensitivity and usefulness of anti-phosphohistone-H3 antibody immunostaining for counting mitotic figures in meningioma cases. Brain Tumor Pathol; 2009;26(2):51-7
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  • [Title] Sensitivity and usefulness of anti-phosphohistone-H3 antibody immunostaining for counting mitotic figures in meningioma cases.
  • Recently, anti-phosphohistone-H3 (PHH3) antibody has been reported as a mitosis-specific marker for meningioma grading.
  • In this study, we attempted PHH3 immunostaining for our meningioma cases and verified not only the sensitivity of PHH3 immunostaining but also that of its usefulness in grading meningiomas.
  • As such, PHH3 may be a sensitive and useful marker for meningioma grading as based on the MF.
  • [MeSH-major] Histones / metabolism. Meningeal Neoplasms / diagnosis. Meningioma / diagnosis. Mitotic Index / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Analysis of Variance. Eosine Yellowish-(YS). Female. Hematoxylin. Humans. Immunohistochemistry. Ki-67 Antigen / metabolism. Male. Middle Aged. Mitosis. Phosphorylation. Sensitivity and Specificity

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  • (PMID = 19856215.001).
  • [ISSN] 1861-387X
  • [Journal-full-title] Brain tumor pathology
  • [ISO-abbreviation] Brain Tumor Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Histones; 0 / Ki-67 Antigen; TDQ283MPCW / Eosine Yellowish-(YS); YKM8PY2Z55 / Hematoxylin
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84. Hanimoglu H, Tanriverdi T, Kacira T, Sanus GZ, Atukeren P, Aydin S, Tunali Y, Gumustas K, Kaynar MY: Relationship between DNA damage and total antioxidant capacity in patients with transitional meningioma. Clin Neurol Neurosurg; 2007 Sep;109(7):561-6
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  • [Title] Relationship between DNA damage and total antioxidant capacity in patients with transitional meningioma.
  • PURPOSE: The purpose of this study was to assess oxidative DNA damage and total antioxidant capacity (TAC) in patients with transitional meningioma (TM) and to compare the results with normal brain tissues.
  • PATIENTS AND METHODS: Oxidative DNA damage and TAC were evaluated in TM extracted from 22 patients and in normal brain tissues of 15 subjects who underwent autopsy within first 4h of death.
  • RESULTS: The median level of TAC in TM (135nmol/gwet tissue) was remarkably lower than in normal brain tissue (298nmol/gwet tissue).
  • [MeSH-major] Antioxidants / metabolism. DNA Damage / physiology. Meningeal Neoplasms / pathology. Meningioma / pathology
  • [MeSH-minor] Adult. Brain / pathology. Deoxyguanosine / analogs & derivatives. Deoxyguanosine / metabolism. Female. Glutathione Peroxidase / metabolism. Glutathione Reductase / metabolism. Humans. Male. Middle Aged. Reactive Oxygen Species / metabolism. Reference Values. Statistics as Topic

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  • (PMID = 17555871.001).
  • [ISSN] 0303-8467
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antioxidants; 0 / Reactive Oxygen Species; 88847-89-6 / 8-oxo-7-hydrodeoxyguanosine; EC 1.11.1.9 / Glutathione Peroxidase; EC 1.8.1.7 / Glutathione Reductase; G9481N71RO / Deoxyguanosine
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85. Shuto T, Inomori S, Fujino H, Nagano H, Hasegawa N, Kakuta Y: Cyst formation following gamma knife surgery for intracranial meningioma. J Neurosurg; 2005 Jan;102 Suppl:134-9
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  • [Title] Cyst formation following gamma knife surgery for intracranial meningioma.
  • CONCLUSIONS: New cyst formation following GKS for benign intracranial meningioma is relatively rare; however, both preexisting and newly developed cysts tend to enlarge after GKS and often require surgery.
  • [MeSH-major] Brain Diseases / etiology. Brain Diseases / surgery. Cysts / etiology. Cysts / surgery. Meningeal Neoplasms / surgery. Meningioma / surgery. Postoperative Complications. Radiosurgery / instrumentation
  • [MeSH-minor] Adult. Aged. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Radiation Dosage

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  • (PMID = 15662796.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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86. Matsuda R, Nikaido Y, Yamada T, Mishima H, Tamaki R: [High-dose radiation-induced meningioma following prophylactic cranial irradiation for acute lymphoblastic leukaemia]. No Shinkei Geka; 2005 Mar;33(3):277-80
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  • [Title] [High-dose radiation-induced meningioma following prophylactic cranial irradiation for acute lymphoblastic leukaemia].
  • The high cure rate in childhood ALL, attributable to aggressive chemotherapy and prophylatic cranial irradiation, is capable of inducing secondary brain tumor.
  • Twelve cases of high-dose radiation-induced meningioma following ALL are also reviewed.
  • [MeSH-major] Cranial Irradiation / adverse effects. Meningeal Neoplasms / etiology. Meningioma / etiology. Neoplasms, Second Primary / etiology. Precursor Cell Lymphoblastic Leukemia-Lymphoma / radiotherapy
  • [MeSH-minor] Adult. Central Nervous System Neoplasms / prevention & control. Female. Humans. Radiotherapy Dosage

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  • (PMID = 15773318.001).
  • [ISSN] 0301-2603
  • [Journal-full-title] No shinkei geka. Neurological surgery
  • [ISO-abbreviation] No Shinkei Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 11
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87. Traunecker H, Mallucci C, Grundy R, Pizer B, Saran F, Children's Cancer and Leukaemia Group: Children's Cancer and Leukaemia Group (CCLG): guidelines for the management of intracranial meningioma in children and young people. Br J Neurosurg; 2008 Feb;22(1):13-25; discussion 24-5
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  • [Title] Children's Cancer and Leukaemia Group (CCLG): guidelines for the management of intracranial meningioma in children and young people.
  • Because of the rarity in children, paediatric meningiomas are often treated according to the adult practice.
  • This may lead to inappropriate treatment considerations since paediatric meningiomas exhibit peculiarities that distinguish them from their adult counterpart.
  • Striking the balance between late toxicities of adjuvant radiotherapy on the growing brain versus the risk of repeated recurrences necessitating surgical interventions in young patients is of importance and will require a clinical decision making process in the paediatric neuro-oncological/neurosurgical MDT tailored to each patient's age and clinical setting.
  • Careful pathological review and multidisciplinary discussions should be undertaken before considering postoperative treatment, such as radiotherapy for histologically anaplastic or clinically aggressive, relapsing meningioma.
  • [MeSH-major] Leukemia / surgery. Meningeal Neoplasms / therapy. Meningioma / therapy
  • [MeSH-minor] Adolescent. Adult. Age Factors. Child. Child, Preschool. Disease Progression. Dose-Response Relationship, Radiation. Female. Humans. Male. Monitoring, Immunologic. Practice Guidelines as Topic. Radiotherapy, Adjuvant / adverse effects. Treatment Outcome

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  • (PMID = 18224517.001).
  • [ISSN] 0268-8697
  • [Journal-full-title] British journal of neurosurgery
  • [ISO-abbreviation] Br J Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 112
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88. Williams HM, Lundberg GA Jr: Systemic lupus erythematosus, meningioma and carcinoma of the cervix--a case report. 1956. Conn Med; 2006 Aug;70(7):453-6
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  • [Title] Systemic lupus erythematosus, meningioma and carcinoma of the cervix--a case report. 1956.
  • The history of a patient with systemic lupus erythematosus, meningioma and carcinoma of the cervix is presented.
  • Although the meningioma originally masqueraded as a cerebral manifestation of lupus, lack of response to cortisone and progression of symptoms eventually indicated the diagnosis of brain tumor.
  • [MeSH-major] Lupus Erythematosus, Systemic / history. Meningioma / history. Uterine Cervical Neoplasms / history
  • [MeSH-minor] Adult. Female. History, 20th Century. Humans


89. Yue Q, Shibata Y, Isobe T, Anno I, Kawamura H, Gong QY, Matsumura A: Absolute choline concentration measured by quantitative proton MR spectroscopy correlates with cell density in meningioma. Neuroradiology; 2009 Jan;51(1):61-7
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  • [Title] Absolute choline concentration measured by quantitative proton MR spectroscopy correlates with cell density in meningioma.
  • INTRODUCTION: This study was aimed to investigate the relationship between quantitative proton magnetic resonance spectroscopy (1H-MRS) and pathological changes in meningioma.
  • MATERIALS AND METHODS: Twenty-two meningioma cases underwent single voxel 1H-MRS (point-resolved spectroscopy sequence, repetition time/echo time = 2,000 ms/68, 136, 272 ms).
  • CONCLUSION: Absolute Cho concentration, especially Cho concentration corrected according to intra-voxel cystic/necrotic parts, reflects cell density of meningioma.
  • [MeSH-major] Brain Neoplasms / chemistry. Brain Neoplasms / pathology. Choline / analysis. Meningioma / chemistry. Meningioma / pathology
  • [MeSH-minor] Adult. Aged. Brain / pathology. Brain Chemistry. Cell Count. Female. Humans. Immunohistochemistry. Linear Models. Magnetic Resonance Spectroscopy. Male. Middle Aged. Protons. Young Adult

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  • (PMID = 19002445.001).
  • [ISSN] 1432-1920
  • [Journal-full-title] Neuroradiology
  • [ISO-abbreviation] Neuroradiology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Protons; N91BDP6H0X / Choline
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90. Kim EY, Weon YC, Kim ST, Kim HJ, Byun HS, Lee JI, Kim JH: Rhabdoid meningioma: clinical features and MR imaging findings in 15 patients. AJNR Am J Neuroradiol; 2007 Sep;28(8):1462-5
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  • [Title] Rhabdoid meningioma: clinical features and MR imaging findings in 15 patients.
  • BACKGROUND AND PURPOSE: Rhabdoid meningioma (RM) is a recently described variant of malignant meningioma, with radiologic features currently not well characterized in the medical literature.
  • After surgery, the patients had follow-up brain MR imaging to evaluate for tumor recurrence.
  • [MeSH-major] Magnetic Resonance Imaging. Meningeal Neoplasms / diagnosis. Meningeal Neoplasms / physiopathology. Meningioma / diagnosis. Meningioma / physiopathology
  • [MeSH-minor] Adult. Aged. Cysts / diagnosis. Edema / chemically induced. Edema / etiology. Female. Follow-Up Studies. Humans. Hyperostosis / diagnosis. Hyperostosis / etiology. Male. Middle Aged. Neurosurgical Procedures. Radiotherapy, Adjuvant. Retrospective Studies. Tomography, X-Ray Computed

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  • (PMID = 17846191.001).
  • [ISSN] 0195-6108
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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91. Einav S, Shoshan Y, Ovadia H, Matot I, Hersch M, Itshayek E: Early postoperative serum S100 beta levels predict ongoing brain damage after meningioma surgery: a prospective observational study. Crit Care; 2006;10(5):R141
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  • [Title] Early postoperative serum S100 beta levels predict ongoing brain damage after meningioma surgery: a prospective observational study.
  • This study evaluated whether pre-/postoperative serum S100beta levels correlate with unfavourable clinical and radiological findings in patients undergoing elective meningioma resection.
  • METHODS: In 52 consecutive patients admitted for meningioma surgery, serum S100beta levels were determined upon admission and immediately, 24 hours, and 48 hours after surgery.
  • Tumour volume, brain edema, and bleeding volume were calculated using BrainSCAN software.
  • Significantly greater postcraniotomy S100beta levels were observed with prolonged surgery (p = 0.039), deterioration in the mini-mental state examination (p = 0.005, 0.011, and 0.036 for pre versus immediate, 24 hours, and 48 hours postsurgery, respectively), and with postoperative brain computed tomography evidence of brain injury; bleeding was associated with higher serum S100beta levels at 24 and 48 hours after surgery (p = 0.046, 95% confidence interval [CI] -0.095 to -0.001 and p = 0.034, 95% CI -0.142 to -0.006, respectively) as was the presence of midline shift (p = 0.005, 95% CI -0.136 to -0.025 and p = 0.006, 95% CI -0.186 to -0.032, respectively).
  • CONCLUSION: In patients with meningioma, serum S100beta levels perform poorly as an indicator of tumour characteristics but may suggest ongoing postcraniotomy injury.
  • Serum S100beta levels may serve as a potentially useful early marker of postcraniotomy brain damage in patients undergoing elective meningioma resection.
  • [MeSH-major] Brain Damage, Chronic / blood. Meningeal Neoplasms / surgery. Meningioma / surgery. Nerve Growth Factors / blood. S100 Proteins / blood
  • [MeSH-minor] Adult. Aged. Biomarkers / blood. Female. Humans. Male. Middle Aged. Postoperative Period. Predictive Value of Tests. Prospective Studies. S100 Calcium Binding Protein beta Subunit. Time Factors

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  • (PMID = 17020600.001).
  • [ISSN] 1466-609X
  • [Journal-full-title] Critical care (London, England)
  • [ISO-abbreviation] Crit Care
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Nerve Growth Factors; 0 / S100 Calcium Binding Protein beta Subunit; 0 / S100 Proteins; 0 / S100B protein, human
  • [Other-IDs] NLM/ PMC1751042
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92. Aghi M, Barker FG 2nd: Benign adult brain tumors: an evidence-based medicine review. Prog Neurol Surg; 2006;19:80-96
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  • [Title] Benign adult brain tumors: an evidence-based medicine review.
  • BACKGROUND: Benign adult brain tumors can be managed conservatively or using surgery, radiation, or medicines.
  • METHODS: Review of the literature on benign adult brain tumors using evidence-based standards and focusing on meningiomas, pituitary adenomas, and vestibular schwannomas, which together represent the majority of WHO grade 1 adult brain tumors.
  • RESULTS: Nearly all studies of benign adult brain tumors were of relatively poor quality (level 3 or poorer).
  • The safety of meningioma surgery in the elderly varies with institution, radiosurgery is a reliable alternative to surgery in small to medium-sized meningiomas, and the efficacy of drugs in therapy of meningiomas recurring after surgery is difficult to interpret due to a lack of uniform criteria in the studies.
  • CONCLUSIONS: While randomized clinical trials comparing conservative management, surgery, radiation, and medical management of benign adult benign tumors are unlikely to occur, there is some level 3 evidence that can assist in their treatment.
  • [MeSH-major] Brain Neoplasms / therapy. Evidence-Based Medicine
  • [MeSH-minor] Adenoma / therapy. Adult. Humans. Meningeal Neoplasms / therapy. Meningioma / therapy. Neuroma, Acoustic / therapy. Neurosurgical Procedures. Phototherapy. Pituitary Neoplasms / therapy. Radiosurgery

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  • (PMID = 17033148.001).
  • [ISSN] 0079-6492
  • [Journal-full-title] Progress in neurological surgery
  • [ISO-abbreviation] Prog Neurol Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 58
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93. Bakar B, Sav A, Tekkok IH: Giant chordoid meningioma symptomatic immediately after pregnancy: report of a rare case. Clin Neuropathol; 2010 May-Jun;29(3):163-8
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  • [Title] Giant chordoid meningioma symptomatic immediately after pregnancy: report of a rare case.
  • BACKGROUND: Chordoid meningioma is a very rare subtype of meningioma with less than 90 cases reported in the literature.
  • Herein, we present a pregnancy-associated case of a chordoid meningioma and briefly discuss possible mechanisms.
  • The postoperative period was uneventful; and histopathological diagnosis was chordoid meningioma.
  • As for this case of chordoid meningioma associated with pregnancy, we think mucin accumulation in tumor could be involved in an increase in the tumor size while delivery procedures with the common anaesthetic and sedative drugs may also have enhanced the peritumoral edema by causing a relative decrease in the cerebral blood flow.
  • [MeSH-major] Meningeal Neoplasms / pathology. Meningioma / pathology. Pregnancy Complications, Neoplastic / pathology
  • [MeSH-minor] Adult. Biopsy. Brain / pathology. Brain Edema / pathology. Brain Edema / radiography. Cesarean Section. Female. Humans. Magnetic Resonance Imaging. Pregnancy. Severity of Illness Index. Tomography, X-Ray Computed

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  • (PMID = 20423691.001).
  • [ISSN] 0722-5091
  • [Journal-full-title] Clinical neuropathology
  • [ISO-abbreviation] Clin. Neuropathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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94. Lee JW, Kang KW, Park SH, Lee SM, Paeng JC, Chung JK, Lee MC, Lee DS: 18F-FDG PET in the assessment of tumor grade and prediction of tumor recurrence in intracranial meningioma. Eur J Nucl Med Mol Imaging; 2009 Oct;36(10):1574-82
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  • [Title] 18F-FDG PET in the assessment of tumor grade and prediction of tumor recurrence in intracranial meningioma.
  • PURPOSE: The purpose of this study was to investigate the role of (18)F-fluorodeoxyglucose (FDG) PET in detecting high-grade meningioma and predicting the recurrence in patients with meningioma after surgical resection.
  • METHODS: Fifty-nine patients (27 men and 32 women) with intracranial meningioma who underwent preoperative FDG PET and subsequent surgical resection were enrolled.
  • The tumor to gray matter ratio (TGR) of FDG uptake was calculated and a receiver-operating characteristic (ROC) curve of the TGR was drawn to determine the cutoff value of the TGR for detection of high-grade meningioma.
  • Further, univariate analysis with the log-rank test was performed to assess the predictive factors of meningioma recurrence.
  • RESULTS: The TGR in high-grade meningioma (WHO grade II and III) was significantly higher than that in low-grade ones (WHO grade I) (p=0.002) and significantly correlated with the MIB-1 labeling index (r=0.338, p=0.009) and mitotic count of the tumor (r=0.284, p=0.03).
  • The ROC analysis revealed that the TGR of 1.0 was the best cutoff value for detecting high-grade meningioma with a sensitivity of 43%, specificity of 95%, and accuracy of 81%.
  • In the log-rank test, the TGR, MIB-1 labeling index, presence of brain invasion, and WHO grade were significantly associated with tumor recurrence.
  • The cumulative recurrence-free survival rate of patients with a TGR of 1.0 or less was significantly higher than that of patients with a TGR of more than 1.0 (p=0.0003) CONCLUSION: FDG uptake in meningioma was the significant predictive factor of tumor recurrence and significantly correlated with the proliferative potential of the tumor.
  • [MeSH-major] Brain Neoplasms / radionuclide imaging. Fluorodeoxyglucose F18. Meningioma / radionuclide imaging. Radiopharmaceuticals
  • [MeSH-minor] Adult. Aged. Disease-Free Survival. Female. Fluorine Radioisotopes. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Recurrence, Local / radionuclide imaging. Positron-Emission Tomography. ROC Curve

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  • (PMID = 19377904.001).
  • [ISSN] 1619-7089
  • [Journal-full-title] European journal of nuclear medicine and molecular imaging
  • [ISO-abbreviation] Eur. J. Nucl. Med. Mol. Imaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Fluorine Radioisotopes; 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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95. Garcia-Conde M, Roldan-Delgado H, Martel-Barth-Hansen D, Manzano-Sanz C: Anaplastic transformation of an atypical intraventricular meningioma with metastases to the liver: case report. Neurocirugia (Astur); 2009 Dec;20(6):541-9
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  • [Title] Anaplastic transformation of an atypical intraventricular meningioma with metastases to the liver: case report.
  • We present herein the first case of a malignant intraventricular meningioma with extraneural metastases.
  • Histological examination demonstrated an atypical meningioma.
  • At surgery at second recurrence, the tumor was more aggressive, invading the brain parenchyma.
  • Histological examination showed anaplastic meningioma.
  • Biopsy was consistent with liver metastases of a malignant meningioma.
  • Therefore, when systemic deterioration occurs in a patient with a malignant intraventricular meningioma, metastases to extraneural organs such as the liver must be ruled out.
  • [MeSH-major] Anaplasia / pathology. Liver Neoplasms / secondary. Meningeal Neoplasms / pathology. Meningioma / pathology
  • [MeSH-minor] Adult. Fatal Outcome. Humans. Magnetic Resonance Imaging / methods. Male. Tomography, X-Ray Computed / methods

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  • (PMID = 19967319.001).
  • [ISSN] 1130-1473
  • [Journal-full-title] Neurocirugía (Asturias, Spain)
  • [ISO-abbreviation] Neurocirugia (Astur)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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96. Kleinerman RA, Linet MS, Hatch EE, Tarone RE, Black PM, Selker RG, Shapiro WR, Fine HA, Inskip PD: Self-reported electrical appliance use and risk of adult brain tumors. Am J Epidemiol; 2005 Jan 15;161(2):136-46
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  • [Title] Self-reported electrical appliance use and risk of adult brain tumors.
  • The authors investigated whether appliances may be associated with adult brain tumors in a hospital-based case-control study at three centers in the United States from 1994 to 1998.
  • A total of 410 glioma, 178 meningioma, and 90 acoustic neuroma cases and 686 controls responded to a self-administered questionnaire about 14 electrical appliances.
  • There was little evidence of association between brain tumors and curling iron, heating pad, vibrating massager, electric blanket, heated water bed, sound system, computer, television, humidifier, microwave oven, and electric stove.
  • In men, meningioma was associated with electric shaver use (odds ratio = 10.9, 95% confidence interval: 2.3, 50), and odds ratios increased with cumulative minutes of use, although they were based on only two nonexposed cases.
  • Overall, results indicate that extremely low frequency electromagnetic fields from commonly used household appliances are unlikely to increase the risk of brain tumors.
  • [MeSH-major] Brain Neoplasms / etiology. Glioma / etiology. Household Articles. Meningeal Neoplasms / etiology. Meningioma / etiology. Neuroma, Acoustic / etiology
  • [MeSH-minor] Adolescent. Adult. Case-Control Studies. Electromagnetic Fields / adverse effects. Female. Humans. Male. Middle Aged. Neoplasms, Radiation-Induced / etiology. Odds Ratio. Risk Factors

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  • (PMID = 15632263.001).
  • [ISSN] 0002-9262
  • [Journal-full-title] American journal of epidemiology
  • [ISO-abbreviation] Am. J. Epidemiol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
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97. Amoli FA, Mehrabani PM, Tari AS: Aggressive orbital optic nerve meningioma with benign microscopic features: a case report. Orbit; 2007 Dec;26(4):271-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Aggressive orbital optic nerve meningioma with benign microscopic features: a case report.
  • Primary optic nerve meningiomas occur at lower ages than meningiomas arising from the coverings of the brain and spinal cord.
  • Here we report the case of a 20-year-old female with an aggressive orbital meningioma referred to the Ophthalmology Department of the Farabi Hospital in Tehran.
  • The patient had a history of orbital meningioma from 10 years ago and several surgical resections due to tumor recurrence during these 10 years.
  • Microscopic study showed meningotheliomatous meningioma with extensive involvement of the optic nerve and invasion of the optic disc, sclera and choroid.
  • [MeSH-major] Meningioma / pathology. Optic Nerve Neoplasms / pathology
  • [MeSH-minor] Adult. Combined Modality Therapy. Female. Humans. Magnetic Resonance Imaging. Neoplasm Invasiveness. Neoplasm Recurrence, Local

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  • (PMID = 18097966.001).
  • [ISSN] 0167-6830
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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98. Ida CM, Rodríguez FJ, Scheithauer BW, Kois N, Vanefsky M, Andersen BJ, Erickson B: Infiltrative chordoid meningioma of the pineal region: a study of 2 cases. Clin Neuropathol; 2007 May-Jun;26(3):111-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Infiltrative chordoid meningioma of the pineal region: a study of 2 cases.
  • Herein we describe two cases of chordoid meningioma with histologic evidence of pineal gland infiltration.
  • CONCLUSIONS: Chordoid meningioma, although rare, may occur in the pineal region.
  • The differential diagnosis of this meningioma subtype in this location is discussed.
  • [MeSH-major] Meningeal Neoplasms / pathology. Meningioma / pathology. Pineal Gland / pathology
  • [MeSH-minor] Adult. Brain Neoplasms / pathology. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Male

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  • (PMID = 19157002.001).
  • [ISSN] 0722-5091
  • [Journal-full-title] Clinical neuropathology
  • [ISO-abbreviation] Clin. Neuropathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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99. Stranjalis G, Korfias S, Psachoulia C, Boviatsis E, Kouyialis A, Protopappa D, Sakas DE: Serum S-100B as an indicator of early postoperative deterioration after meningioma surgery. Clin Chem; 2005 Jan;51(1):202-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Serum S-100B as an indicator of early postoperative deterioration after meningioma surgery.
  • BACKGROUND: S-100B protein is an established serum marker of primary and secondary brain damage in head injury and stroke.
  • In this study we aimed to correlate serum S-100B values with early postoperative neurologic course as well as late outcome in meningioma surgery.
  • METHODS: We enrolled 50 consecutive patients who underwent meningioma resection.
  • In addition, multiple logistic regression showed that age, sex, site, preoperative edema, history of meningioma resection, extent of resection, and histologic type did not correlate with postoperative increases in S-100B.
  • CONCLUSIONS: After meningioma excision, postcraniotomy increases in serum S-100B appear to be an early indicator of short-term postoperative neurologic deterioration and of a poor longer-term outcome.
  • [MeSH-major] Craniotomy / adverse effects. Meningeal Neoplasms / surgery. Meningioma / surgery. Nervous System Diseases / diagnosis. S100 Proteins / blood
  • [MeSH-minor] Adult. Age Factors. Aged. Aged, 80 and over. Biomarkers / blood. Brain Edema / diagnosis. Brain Edema / etiology. Female. Humans. Male. Middle Aged. Nerve Growth Factors. Predictive Value of Tests. Prognosis. ROC Curve. Regression Analysis. S100 Calcium Binding Protein beta Subunit. Serum. Sex Factors

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  • (PMID = 15550475.001).
  • [ISSN] 0009-9147
  • [Journal-full-title] Clinical chemistry
  • [ISO-abbreviation] Clin. Chem.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Nerve Growth Factors; 0 / S100 Calcium Binding Protein beta Subunit; 0 / S100 Proteins
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100. Schüz J, Böhler E, Schlehofer B, Berg G, Schlaefer K, Hettinger I, Kunna-Grass K, Wahrendorf J, Blettner M: Radiofrequency electromagnetic fields emitted from base stations of DECT cordless phones and the risk of glioma and meningioma (Interphone Study Group, Germany). Radiat Res; 2006 Jul;166(1 Pt 1):116-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radiofrequency electromagnetic fields emitted from base stations of DECT cordless phones and the risk of glioma and meningioma (Interphone Study Group, Germany).
  • The objective of this study was to test the hypothesis that exposure to continuous low-level radiofrequency electromagnetic fields (RF EMFs) increases the risk of glioma and meningioma.
  • Participants in a population-based case-control study in Germany on the risk of brain tumors in relation to cellular phone use were 747 incident brain tumor cases between the ages of 30 and 69 years and 1494 matched controls.
  • Estimated odds ratios were 0.82 (95% confidence interval: 0.29-2.33) for glioma and 0.83 (0.29-2.36) for meningioma.
  • Although the study was limited due to the small number of exposed subjects, it is still a first indication that residential low-level exposure to RF EMFs may not pose a higher risk of brain tumors.
  • [MeSH-major] Brain Neoplasms / epidemiology. Cell Phones / statistics & numerical data. Electromagnetic Fields. Environmental Exposure / statistics & numerical data. Glioma / epidemiology. Meningioma / epidemiology. Neoplasms, Radiation-Induced / epidemiology
  • [MeSH-minor] Adult. Aged. Case-Control Studies. Female. Germany / epidemiology. Humans. Incidence. Male. Microwaves. Middle Aged. Proportional Hazards Models. Risk Assessment / methods. Risk Factors






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