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1. Lazova R, McNiff JM, Glusac EJ, Godic A: Promontory sign--present in patch and plaque stage of angiosarcoma! Am J Dermatopathol; 2009 Apr;31(2):132-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Promontory sign--present in patch and plaque stage of angiosarcoma!
  • Kaposi sarcoma is characterized by a proliferation of irregular jagged vascular channels, which partly surround preexisting blood vessels in some areas.
  • Cutaneous angiosarcoma (AS) is a malignant vascular neoplasm comprised of a meshwork of anastomosing irregular dilated vessels between collagen bundles and around skin appendages, lined by atypical endothelial cells.
  • The presence of promontory sign has not been emphasized in lesions other than Kaposi sarcoma, but seems to be a feature that is not uncommon in patch/plaque stage AS.
  • [MeSH-major] Dermis / pathology. Endothelial Cells / pathology. Hemangiosarcoma / pathology. Sarcoma, Kaposi / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biopsy. Cell Division. Databases, Factual. Female. Humans. Male. Middle Aged

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  • (PMID = 19318797.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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2. O'Callaghan DS, Breen DP, Young V: Angiosarcoma of the right atrium masquerading as recurrent pulmonary embolism. Thorac Cardiovasc Surg; 2008 Dec;56(8):488-90
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  • [Title] Angiosarcoma of the right atrium masquerading as recurrent pulmonary embolism.
  • Primary cardiac angiosarcoma is a rare tumor that may present with features mimicking venous thromboembolic disease, making the diagnosis particularly challenging.
  • We report a case of angiosarcoma masquerading as recurrent pulmonary embolism successfully treated by radical surgery and adjuvant cytotoxic chemotherapy.
  • [MeSH-major] Heart Neoplasms / diagnosis. Hemangiosarcoma / diagnosis. Pulmonary Embolism / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Heart Aneurysm. Humans. Male. Recurrence

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  • (PMID = 19012217.001).
  • [ISSN] 0171-6425
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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3. Bioulac-Sage P, Laumonier H, Laurent C, Blanc JF, Balabaud C: Benign and malignant vascular tumors of the liver in adults. Semin Liver Dis; 2008 Aug;28(3):302-14
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  • Vascular tumors of the liver in adult patients include cavernous hemangioma, a common benign tumor; epithelioid hemangioendothelioma, a rare, usually low-grade malignant tumor; and angiosarcoma, a rare and very aggressive tumor.
  • A definitive diagnosis of epithelioid hemangioendothelioma and angiosarcoma requires histopathologic examination.
  • The prognosis of angiosarcoma remains dismal.
  • [MeSH-minor] Adult. Hemangioendothelioma, Epithelioid / pathology. Hemangioendothelioma, Epithelioid / therapy. Hemangioma, Cavernous / pathology. Hemangioma, Cavernous / therapy. Hemangiosarcoma / pathology. Hemangiosarcoma / therapy. Hepatic Stellate Cells / pathology. Humans. Sarcoma, Kaposi / pathology. Sarcoma, Kaposi / therapy. Treatment Outcome

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  • (PMID = 18814083.001).
  • [ISSN] 0272-8087
  • [Journal-full-title] Seminars in liver disease
  • [ISO-abbreviation] Semin. Liver Dis.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 45
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4. Benoit L, Arnould L, Cheynel N, Goui S, Collin F, Fraisse J, Cuisenier J: The role of surgery and treatment trends in uterine sarcoma. Eur J Surg Oncol; 2005 May;31(4):434-42
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  • [Title] The role of surgery and treatment trends in uterine sarcoma.
  • AIMS: To report a series of uterine sarcomas treated in one institution.
  • METHODS: We report 72 cases of uterine sarcomas treated in a single institution, comparing the periods 1966-1989 and 1990-2001.
  • RESULTS: The histological types consisted in 34 leiomyosarcomas, 25 mixte mullerian tumours, 12 endometrial stromal sarcoma and one angiosarcoma.
  • [MeSH-major] Sarcoma / surgery. Uterine Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Chemotherapy, Adjuvant. Combined Modality Therapy. Female. Humans. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging. Proportional Hazards Models. Radiotherapy, Adjuvant. Survival Rate

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  • (PMID = 15837053.001).
  • [ISSN] 0748-7983
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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5. Ortiz Mendoza CM: [Recurrent breast haematoma after fine needle aspiration biopsy of angiosarcoma]. Ginecol Obstet Mex; 2007 Mar;75(3):164-7
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  • [Title] [Recurrent breast haematoma after fine needle aspiration biopsy of angiosarcoma].
  • [Transliterated title] Hematoma mamario recidivante posterior a la biopsia por aspiración con aguja delgada en un angiosarcoma.
  • It is reported a rare complication after a fine needle aspiration biopsy of a breast angiosarcoma.
  • Four months later a recurrence presented, and a new excision was carried out with a resulting moderately differentiated angiosarcoma, then a simple mastectomy was performed for definitive treatment.
  • A recurrent haematoma after a fine needle aspiration biopsy of a breast tumor mandates to rule out an angiosarcoma.
  • [MeSH-major] Biopsy, Fine-Needle / adverse effects. Breast / injuries. Breast Neoplasms / pathology. Hemangiosarcoma / pathology. Hematoma / etiology
  • [MeSH-minor] Adult. Female. Humans. Mastectomy. Recurrence

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  • (PMID = 17547091.001).
  • [ISSN] 0300-9041
  • [Journal-full-title] Ginecología y obstetricia de México
  • [ISO-abbreviation] Ginecol Obstet Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
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6. Simpson L, Kumar SK, Okuno SH, Schaff HV, Porrata LF, Buckner JC, Moynihan TJ: Malignant primary cardiac tumors: review of a single institution experience. Cancer; 2008 Jun;112(11):2440-6
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  • BACKGROUND: Primary cardiac sarcomas are uncommon.
  • The authors undertook to review the Mayo Clinic's experience with primary cardiac sarcomas consisting of 34 patients seen over a 32-year period.
  • Thirty-four patients with primary cardiac sarcomas were identified and their medical records reviewed for details pertaining to presenting symptoms, staging modalities, treatment approaches, and outcomes.
  • The most common histologic type was angiosarcoma (41%).
  • Patients with angiosarcoma had a lower survival compared with patients with other histologies (5 months vs 17 months; P = .01).
  • CONCLUSIONS: Cardiac sarcomas remain a rare but lethal disease.
  • Compared with extracardiac sarcomas, the prognosis for patients with cardiac sarcomas remains very poor.
  • [MeSH-major] Heart Neoplasms / pathology. Sarcoma / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Disease-Free Survival. Female. Humans. Male. Middle Aged. Neoplasm Staging. Prognosis. Survival Rate. Treatment Outcome

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  • [Copyright] (c) 2008 American Cancer Society.
  • (PMID = 18428209.001).
  • [ISSN] 1097-0142
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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7. Li Q, Wang J, Sun Y, Cui Y, Hao X: Hepatic angiosarcoma arising in an adult mesenchymal hamartoma. Int Semin Surg Oncol; 2007;4:3
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  • [Title] Hepatic angiosarcoma arising in an adult mesenchymal hamartoma.
  • The histogenesis of the hepatic sarcoma and its association with hamartoma is not well understood.
  • We hereby present a Chinese patient with hepatic angiosarcoma arising from an adult mesenchymal hamartoma of liver.
  • Now she was admitted to our hospital with some unusual features: (a) this patient was diagnosed in mid-twenties, (b) the tumor occupied the whole liver and most importantly (c) the hepatic angiosarcoma appeared 8 years after the diagnosis of hamartoma.
  • Based on this case and some reports, hepatic hamartoma may develop to hepatic angiosarcoma.

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  • (PMID = 17257403.001).
  • [ISSN] 1477-7800
  • [Journal-full-title] International seminars in surgical oncology : ISSO
  • [ISO-abbreviation] Int Semin Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1796548
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8. Villalpando-Mendoza E, Pérez-Pérez FM, Cortés-Flores AO, Velázquez-Ramírez GA, Fuentes-Orozco C, González-Ojeda A: [Frequency of heart tumors and their histopathological correlation]. Cir Cir; 2006 May-Jun;74(3):183-7
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  • Eighty percent of primary heart neoplasias are benign, and myxomas represent the first cause in frequency among adult populations.
  • Clinical diagnosis was determined in 15 patients (94%) and just one case of intracardiac thrombus (6%), whereas the histopathologic diagnosis reported myxoma in only 11 cases (68.8%), three patients with intra-cardiac thrombus (18.7%) and two patients with sarcomas (12.5%), leiomiosarcoma and angiosarcoma, respectively.

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  • (PMID = 16875518.001).
  • [ISSN] 0009-7411
  • [Journal-full-title] Cirugía y cirujanos
  • [ISO-abbreviation] Cir Cir
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Mexico
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9. Wan Musa WR, Abdulwakil Elraied MA, Phang KS, Kwah YG, Tan SP, Harun R, Ban AY: Primary epithelioid angiosarcoma of the lung presenting as left-sided shoulder pain. Ann Acad Med Singapore; 2010 Aug;39(8):658-9
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  • [Title] Primary epithelioid angiosarcoma of the lung presenting as left-sided shoulder pain.
  • [MeSH-major] Hemangiosarcoma / complications. Lung Neoplasms / complications. Sarcoma / complications. Shoulder Pain / diagnosis
  • [MeSH-minor] Humans. Male. Young Adult

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  • (PMID = 20838710.001).
  • [ISSN] 0304-4602
  • [Journal-full-title] Annals of the Academy of Medicine, Singapore
  • [ISO-abbreviation] Ann. Acad. Med. Singap.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Singapore
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10. Bansal M, Mehrotra R, Agrawal V, Kasliwal RR, Trehan N: Primary tumor of the heart. Angiosarcoma. Indian Heart J; 2009 Jul-Aug;61(4):383
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary tumor of the heart. Angiosarcoma.
  • [MeSH-major] Heart Neoplasms / diagnosis. Hemangiosarcoma / diagnosis
  • [MeSH-minor] Adult. Humans. Lymphoma / diagnosis. Male

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  • (PMID = 20635745.001).
  • [ISSN] 0019-4832
  • [Journal-full-title] Indian heart journal
  • [ISO-abbreviation] Indian Heart J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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11. Mezzabotta M, Riccardi S, Bonvini S, Declich P, Tavani E, Morandi E: Giant nodular pseudoangiomatous stromal hyperplasia (PASH) of the breast presenting as a rapidly growing tumour. Chir Ital; 2009 May-Jun;61(3):369-73
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • It is important to distinguish this benign lesion from a low-grade angiosarcoma.
  • [MeSH-minor] Adult. Breast Neoplasms / pathology. Diagnosis, Differential. Female. Humans. Hyperplasia / surgery. Incidental Findings. Treatment Outcome


12. Sun HY, Zheng M, Liu WL, Zhou JF, Deng JN, Huang M: [The clinical application of splenectomy in pyrexia of unknown origin with splenomegaly]. Zhonghua Nei Ke Za Zhi; 2005 Feb;44(2):89-91
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  • RESULTS: In these 35 patients, there were 17 cases of non-Hodgkin's lymphoma (48.6%), 5 cases of Hodgkin's disease (14.2%), 2 cases of malignant histiocytosis (5.7%), 5 cases of connective tissue disease (14.2%), 2 cases of chronic congestive splenomegaly (5.7%), 1 case of hemophagocytic syndrome (2.9%), 1 case of remote spleen infarction (2.9%), 1 case of tuberculosis of spleen (2.9%) and 1 case of spleen angiosarcoma (2.9%).
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Male. Middle Aged. Retrospective Studies. Spleen / pathology

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  • (PMID = 15840216.001).
  • [ISSN] 0578-1426
  • [Journal-full-title] Zhonghua nei ke za zhi
  • [ISO-abbreviation] Zhonghua Nei Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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13. Cardinale L, Mirra M, Galli C, Goldblum JR, Pizzolitto S, Falconieri G: Angiosarcoma of the uterus: report of 2 new cases with deviant clinicopathologic features and review of the literature. Ann Diagn Pathol; 2008 Jun;12(3):217-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma of the uterus: report of 2 new cases with deviant clinicopathologic features and review of the literature.
  • A few cases of uterine angiosarcoma have been detailed in the literature: 2 new cases are herein described featuring some unusual clinical or phenotypic differences compared with previously published cases, such as occurrence in premenopausal age or a poorly differentiated histology.
  • Occurrence in childbearing age or a deviant histologic pattern, as documented in this report, may be added to the clinicopathologic spectrum of uterine angiosarcoma.
  • [MeSH-major] Hemangiosarcoma / secondary. Uterine Neoplasms / pathology
  • [MeSH-minor] Adult. Aged, 80 and over. Antigens, CD / analysis. Biomarkers, Tumor / analysis. Diagnosis, Differential. Factor VIII / analysis. Fatal Outcome. Female. Humans. Immunohistochemistry. Leiomyosarcoma / diagnosis. Necrosis

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  • (PMID = 18486900.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Biomarkers, Tumor; 9001-27-8 / Factor VIII
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14. Brinckman SL, van der Wouw P: Images in cardiovascular medicine. Angiosarcoma of the pericardium: a fatal disease. Circulation; 2005 Jun 14;111(23):e388-9
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  • [Title] Images in cardiovascular medicine. Angiosarcoma of the pericardium: a fatal disease.
  • [MeSH-major] Heart Neoplasms / pathology. Hemangiosarcoma / pathology. Pericardium / pathology
  • [MeSH-minor] Adult. Echocardiography. Heart Ventricles / pathology. Heart Ventricles / ultrasonography. Humans. Magnetic Resonance Imaging. Male

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  • (PMID = 15956142.001).
  • [ISSN] 1524-4539
  • [Journal-full-title] Circulation
  • [ISO-abbreviation] Circulation
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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15. Suppiah R, Wood L, Elson P, Budd GT: Phase I/II study of docetaxel, ifosfamide, and doxorubicin in advanced, recurrent, or metastatic soft tissue sarcoma (STS). Invest New Drugs; 2006 Nov;24(6):509-14
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Phase I/II study of docetaxel, ifosfamide, and doxorubicin in advanced, recurrent, or metastatic soft tissue sarcoma (STS).
  • HISTOLOGY: leiomyosarcoma 10, spindle cell sarcoma 3, synovial sarcoma 2, angiosarcoma 1, fibrous histiocytoma 1, epitheliod hemangio-endothelioma 1, and 3 not specified.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Sarcoma / drug therapy
  • [MeSH-minor] Adult. Aged. Antineoplastic Agents, Alkylating / administration & dosage. Doxorubicin / administration & dosage. Female. Humans. Ifosfamide / administration & dosage. Male. Maximum Tolerated Dose. Middle Aged. Survival Analysis. Taxoids / administration & dosage

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  • (PMID = 16791410.001).
  • [ISSN] 0167-6997
  • [Journal-full-title] Investigational new drugs
  • [ISO-abbreviation] Invest New Drugs
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article
  • [Publication-country] United States
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16. Guo CC, Punar M, Contreras AL, Tu SM, Pisters L, Tamboli P, Czerniak B: Testicular germ cell tumors with sarcomatous components: an analysis of 33 cases. Am J Surg Pathol; 2009 Aug;33(8):1173-8
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  • The most common histologic type of SC was rhabdomyosarcoma (n=24), followed by high-grade unclassified sarcoma (n=5), rhabdomyosarcoma admixed with high-grade unclassified sarcoma (n=2), angiosarcoma (n=1), and low-grade myxoid sarcoma (n=1).

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  • (PMID = 19561445.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P50 CA091846; United States / NCI NIH HHS / CA / CA091846-100006; United States / NCI NIH HHS / CA / U01 CA085078-10; United States / NCI NIH HHS / CA / CA085078-10; United States / NCI NIH HHS / CA / U01 CA085078; United States / NCI NIH HHS / CA / P50 CA091846-100006
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS229448; NLM/ PMC3812063
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17. Gyorffy H: [Study of claudins and prognostic factors in some gastrointestinal diseases]. Magy Onkol; 2009 Dec;53(4):377-83
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  • GIST, angiosarcoma, hemangioma, leiomyosarcoma and leiomyoma showed expression of various CLDNs.
  • [MeSH-minor] Adenocarcinoma / metabolism. Adolescent. Adult. Aged. Aged, 80 and over. Barrett Esophagus / metabolism. Carcinoma, Squamous Cell / metabolism. Child. Child, Preschool. Claudin-3. Female. Fluorescent Antibody Technique. Gastrointestinal Stromal Tumors / metabolism. Gene Expression Regulation, Neoplastic. Hemangiosarcoma / metabolism. Humans. Immunohistochemistry. Leiomyosarcoma / metabolism. Male. Membrane Proteins / metabolism. Middle Aged. Predictive Value of Tests. Prognosis. RNA, Messenger / metabolism. Risk Factors. Young Adult

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  • (PMID = 20071310.001).
  • [ISSN] 0025-0244
  • [Journal-full-title] Magyar onkologia
  • [ISO-abbreviation] Magy Onkol
  • [Language] hun
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Hungary
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CLDN3 protein, human; 0 / Claudin-3; 0 / Claudins; 0 / Membrane Proteins; 0 / RNA, Messenger
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18. Bernardos L, García Marín A, Rey Valcárcel C, Martín Gil J, Turégano Fuentes F: [Hepatic angiosarcoma]. Rev Esp Enferm Dig; 2008 Dec;100(12):804-6
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  • [Title] [Hepatic angiosarcoma].
  • [Transliterated title] Angiosarcoma hepático.
  • [MeSH-major] Hemangiosarcoma / pathology. Liver Neoplasms / pathology
  • [MeSH-minor] Adult. Female. Humans. Male. Middle Aged

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  • (PMID = 19222346.001).
  • [ISSN] 1130-0108
  • [Journal-full-title] Revista española de enfermedades digestivas : organo oficial de la Sociedad Española de Patología Digestiva
  • [ISO-abbreviation] Rev Esp Enferm Dig
  • [Language] spa
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Spain
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19. Govender PS: Atypical presentation of angiosarcoma of the scalp in the setting of human immunodeficiency virus (HIV). World J Surg Oncol; 2009;7:99
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  • [Title] Atypical presentation of angiosarcoma of the scalp in the setting of human immunodeficiency virus (HIV).
  • BACKGROUND: Angiosarcoma of the head and neck is an uncommon, aggressive malignant entity most commonly found in elderly Caucasian males.
  • The atypical gender, age and race of the patient reflect the unusual clinical presentation of this case of angiosarcoma, attributable to the patient's HIV status.
  • [MeSH-major] HIV Infections / complications. HIV-1 / pathogenicity. Head and Neck Neoplasms / etiology. Hemangiosarcoma / etiology. Scalp / pathology
  • [MeSH-minor] Adult. Anthracyclines / administration & dosage. Antineoplastic Combined Chemotherapy Protocols. CD4 Lymphocyte Count. Combined Modality Therapy. Female. Humans. Ifosfamide / administration & dosage. Radiotherapy Dosage. Young Adult


20. Hsu JT, Chen HM, Lin CY, Yeh CN, Hwang TL, Jan YY, Chen MF: Primary angiosarcoma of the spleen. J Surg Oncol; 2005 Dec 15;92(4):312-6
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  • [Title] Primary angiosarcoma of the spleen.
  • BACKGROUND AND OBJECTIVES: Primary splenic angiosarcoma is a very rare and aggressive neoplasm with a high metastatic rate and dismal prognosis.
  • METHODS: The records of all cases of primary splenic angiosarcoma treated at Chang Gung Memorial Hospital from April 1991 to July 2004 were retrospectively reviewed.
  • CONCLUSIONS: The clinical presentations of splenic angiosarcoma were similar to those of previous reports apart from the higher rate of splenomegaly observed in this study.
  • [MeSH-major] Hemangiosarcoma. Splenic Neoplasms
  • [MeSH-minor] Adult. Aged. Child. Disease-Free Survival. Female. Gastrointestinal Hemorrhage / etiology. Hemoperitoneum / etiology. Humans. Male. Middle Aged. Prognosis. Retrospective Studies. Splenectomy. Splenic Rupture / etiology. Splenomegaly / etiology. Thrombocytopenia / etiology

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  • [Copyright] 2005 Wiley-Liss, Inc.
  • (PMID = 16299797.001).
  • [ISSN] 0022-4790
  • [Journal-full-title] Journal of surgical oncology
  • [ISO-abbreviation] J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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21. Altan E, Arslan C, Dede D, Dogan E, Altundag K: Primary angiosarcoma of the breast after pregnancy. Am Surg; 2010 Aug;76(8):E115
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  • [Title] Primary angiosarcoma of the breast after pregnancy.
  • [MeSH-major] Breast Neoplasms. Hemangiosarcoma
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Female. Humans. Mastectomy. Ultrasonography, Mammary

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  • (PMID = 21513627.001).
  • [ISSN] 0003-1348
  • [Journal-full-title] The American surgeon
  • [ISO-abbreviation] Am Surg
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
  • [Chemical-registry-number] Angiosarcoma of the breast
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22. Zambrano E, Pérez-Atayde AR, Ahrens W, Reyes-Múgica M: Pediatric sclerosing rhabdomyosarcoma. Int J Surg Pathol; 2006 Jul;14(3):193-9
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  • Sclerosing rhabdomyosarcoma, a particular phenotypic variant of rhabdomyosarcoma initially described in the adult population, has emerged as a potential pitfall in the evaluation of pediatric sarcomas.
  • Because of its densely hyalinized collagenous matrix and its occasional expression of a pseudovascular pattern of growth, sclerosing rhabdomyosarcoma has been at times misdiagnosed as chondrosarcoma, osteosarcoma, or angiosarcoma.

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  • (PMID = 16959698.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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23. Akiyama T, Hamazaki S, Monobe Y, Nishimura H, Irei I, Sadahira Y: Sphingosine-1-phosphate receptor 1 is a useful adjunct for distinguishing vascular neoplasms from morphological mimics. Virchows Arch; 2009 Feb;454(2):217-22
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  • S1P(1) expression was observed in eight of eight hemangiomas, four of four lymphangiomas, four of four epithelioid hemangioendotheliomas, three of three Kaposi's sarcomas, and 15 of 15 angiosarcomas with vasoformative, spindle, epithelioid, and undifferentiated features.
  • Conventional analysis and use of a tissue microarray of soft tissue tumors revealed three of 21 liposarcomas to have weak cytoplasmic staining and one of five squamous cell carcinomas to have membranous staining in a very limited area among 115 nonvascular tumors including histological mimics of angiosarcoma such as undifferentiated carcinoma, melanoma, and epithelioid sarcoma.
  • The sensitivity with regards to the angiosarcoma cases was equal to, or even exceeded in undifferentiated angiosarcoma, that of CD31.
  • [MeSH-minor] Adult. Aged. Female. Hemangioma / diagnosis. Hemangiosarcoma / diagnosis. Humans. Immunohistochemistry. Lymphangioma / diagnosis. Male. Middle Aged

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  • (PMID = 19005676.001).
  • [ISSN] 1432-2307
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Receptors, Lysosphingolipid
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24. Seok JY, Kim YB: [Primary angiosarcoma of the liver]. Korean J Hepatol; 2009 Jun;15(2):216-21
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  • [Title] [Primary angiosarcoma of the liver].
  • [MeSH-major] Hemangiosarcoma / pathology. Liver Neoplasms / pathology
  • [MeSH-minor] Adult. Antigens, CD34 / metabolism. Female. Humans

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  • (PMID = 19581774.001).
  • [ISSN] 1738-222X
  • [Journal-full-title] The Korean journal of hepatology
  • [ISO-abbreviation] Korean J Hepatol
  • [Language] kor
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Chemical-registry-number] 0 / Antigens, CD34
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25. Liu H, Zhao J, Fan Y, Fu XL, Fu L: [Clinical and pathologic characteristics of primary angiosarcoma of breast]. Zhonghua Bing Li Xue Za Zhi; 2006 Oct;35(10):598-601
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  • [Title] [Clinical and pathologic characteristics of primary angiosarcoma of breast].
  • OBJECTIVE: To study the clinical and pathologic characteristics of primary angiosarcoma of breast.
  • METHODS: Five cases of primary angiosarcoma of breast were reviewed.
  • CONCLUSIONS: Primary angiosarcoma of breast is a rare entity.
  • [MeSH-major] Breast Neoplasms / pathology. Breast Neoplasms, Male / pathology. Hemangiosarcoma / pathology
  • [MeSH-minor] Adult. Antigens, CD31 / metabolism. Antigens, CD34 / metabolism. Breast / metabolism. Breast / pathology. Breast / surgery. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Immunohistochemistry. Male. Mastectomy / methods. Middle Aged. von Willebrand Factor / metabolism

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  • (PMID = 17134567.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, CD31; 0 / Antigens, CD34; 0 / von Willebrand Factor
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26. Kanat O, Ozet A, Ataergin SA, Arpaci F, Ozturk B, Arpaci F, Ozturk M, Komurcu S, Kuzhan O: A case of advanced scalp angiosarcoma successfully treated with combination chemotherapy of adriamycin, cisplatin and ifosfamide. Clin Oncol (R Coll Radiol); 2006 Jun;18(5):426-7
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  • [Title] A case of advanced scalp angiosarcoma successfully treated with combination chemotherapy of adriamycin, cisplatin and ifosfamide.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Head and Neck Neoplasms / drug therapy. Hemangiosarcoma / drug therapy. Scalp / drug effects. Skin Neoplasms / drug therapy
  • [MeSH-minor] Adult. Cisplatin / administration & dosage. Doxorubicin / administration & dosage. Humans. Ifosfamide / administration & dosage. Male. Treatment Outcome

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  • (PMID = 16817336.001).
  • [ISSN] 0936-6555
  • [Journal-full-title] Clinical oncology (Royal College of Radiologists (Great Britain))
  • [ISO-abbreviation] Clin Oncol (R Coll Radiol)
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
  • [Chemical-registry-number] 80168379AG / Doxorubicin; Q20Q21Q62J / Cisplatin; UM20QQM95Y / Ifosfamide
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27. Gagner JP, Yim JH, Yang GC: Fine-needle aspiration cytology of epithelioid angiosarcoma: a diagnostic dilemma. Diagn Cytopathol; 2005 Dec;33(6):429-33
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  • [Title] Fine-needle aspiration cytology of epithelioid angiosarcoma: a diagnostic dilemma.
  • On the basis of cytologic features on smears, high-grade sarcoma was reported.
  • The case was sent for expert consultation, and the expert's opinion was epithelioid angiosarcoma.
  • The clinical presentation, cytology, histology, and immunohistochemistry of the current case and 15 other cases of epithelioid angiosarcoma found in the cytology literature are summarized.
  • [MeSH-major] Hemangiosarcoma / pathology. Iliac Vein / pathology. Vascular Neoplasms / pathology
  • [MeSH-minor] Adult. Biopsy, Fine-Needle. Diagnosis, Differential. Diagnostic Errors. Epithelioid Cells / pathology. Female. Humans. Immunohistochemistry. Venous Thrombosis / radiography

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  • (PMID = 16299742.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 24
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28. Eilender D, LoRusso P, Thomas L, McCormick C, Rodgers AH, Hooper CL, Tornyos K, Krementz ET, Parker S, Morgan LR: 4,4'-Dihydroxybenzophenone-2,4-dinitrophenylhydrazone (A-007): a topical treatment for cutaneous metastases from malignant cancers. Cancer Chemother Pharmacol; 2006 Jun;57(6):719-26
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PATIENTS AND METHODS: This is a multicenter study involving 27 patients with inoperable skin lesions from histologically confirmed cancers of the breast and oral cavity, non-Hodgkin's lymphoma, Kaposi's sarcoma, and angiosarcoma that had failed radiotherapy or systemic treatment.
  • [MeSH-minor] Administration, Topical. Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Multicenter Studies as Topic

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  • (PMID = 16184382.001).
  • [ISSN] 0344-5704
  • [Journal-full-title] Cancer chemotherapy and pharmacology
  • [ISO-abbreviation] Cancer Chemother. Pharmacol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA 16672; United States / NCI NIH HHS / CA / CA 49310; United States / NCI NIH HHS / CA / CA 89772
  • [Publication-type] Clinical Trial; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / 4,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone; 0 / Antineoplastic Agents; 0 / Hydrazones; 0 / Phenols
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29. Campos MS, Garcia-Rejas RA, Pinto DS Jr, de Sousa SC, Nunes FD: Intravascular papillary endothelial hyperplasia: report of 4 cases with immunohistochemical findings. Med Oral Patol Oral Cir Bucal; 2009 Oct;14(10):e506-9
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  • Intravascular papillary endothelial hyperplasia (IPEH) is a benign endothelial proliferation, usually intravascular, that may mimic angiosarcoma.
  • [MeSH-minor] Adult. Aged. Female. Humans. Hyperplasia. Immunohistochemistry. Male. Middle Aged

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  • (PMID = 19680216.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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30. Amonkar GP, Deshpande JR: Cardiac angiosarcoma. Cardiovasc Pathol; 2006 Jan-Feb;15(1):57-8
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  • [Title] Cardiac angiosarcoma.
  • Myxoma is the most common primary cardiac tumor, while angiosarcoma is the commonest primary malignant tumor.
  • A complete autopsy was performed and a diagnosis of cardiac angiosarcoma was confirmed on histology and immunohistochemistry.
  • [MeSH-major] Heart Neoplasms / pathology. Hemangiosarcoma / secondary
  • [MeSH-minor] Adult. Fatal Outcome. Heart Atria / pathology. Humans. Immunohistochemistry. Lung Neoplasms / secondary. Male

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  • (PMID = 16414459.001).
  • [ISSN] 1054-8807
  • [Journal-full-title] Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology
  • [ISO-abbreviation] Cardiovasc. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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31. Scholsem M, Raket D, Flandroy P, Sciot R, Deprez M: Primary temporal bone angiosarcoma: a case report. J Neurooncol; 2005 Nov;75(2):121-5
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  • [Title] Primary temporal bone angiosarcoma: a case report.
  • We present a rare case of temporal bone angiosarcoma diagnosed in a 26-year-old female patient at 36 week of pregnancy.
  • Pathological findings were those of a poorly differentiated, highly malignant sarcoma with a large epitheloid component and immunohistochemical evidence of endothelial differentiation (CD31, Factor VIII related antigen, CD34), consistent with an angiosarcoma with epitheloid features.
  • We present a rare case of primary temporal bone angiosarcoma and report our experience with a multimode therapeutic approach combining surgery, radiotherapy and chemotherapy.
  • [MeSH-major] Hemangiosarcoma / diagnosis. Pregnancy Complications, Neoplastic / diagnosis. Skull Neoplasms / diagnosis. Skull Neoplasms / pathology. Temporal Bone
  • [MeSH-minor] Adult. Angiography. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bone Neoplasms / secondary. Combined Modality Therapy. Fatal Outcome. Female. Follow-Up Studies. Humans. Lung Neoplasms / secondary. Pregnancy. Pregnancy Trimester, Third. Tomography, X-Ray Computed

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  • (PMID = 16132518.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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32. Ahmad Z, Nisa A, Idrees R, Minhas K, Pervez S, Mumtaz K: Hepatic angiosarcoma with metastasis to small intestine. J Coll Physicians Surg Pak; 2008 Jan;18(1):50-2
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  • [Title] Hepatic angiosarcoma with metastasis to small intestine.
  • Hepatic angiosarcomas are rare tumours with poor prognosis, with patients usually dying within 6 months.
  • Similarly, primary or metastatic angiosarcomas in small intestine are extremely rare, often present with recurrent gastrointestinal bleeding and anemia, and have an extremely poor prognosis.
  • Both primary or metastatic intestinal angiosarcomas may exhibit epithelioid morphology.
  • [MeSH-major] Hemangiosarcoma / pathology. Ileal Neoplasms / secondary. Intestine, Small / pathology. Jejunal Neoplasms / secondary. Liver Neoplasms / pathology
  • [MeSH-minor] Adult. Humans. Male

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  • (PMID = 18452671.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
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33. Tatsas AD, Keedy VL, Florell SR, Simpson JF, Coffin CM, Kelley MC, Cates JM: Foamy cell angiosarcoma: a rare and deceptively bland variant of cutaneous angiosarcoma. J Cutan Pathol; 2010 Aug;37(8):901-6
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  • [Title] Foamy cell angiosarcoma: a rare and deceptively bland variant of cutaneous angiosarcoma.
  • Cutaneous angiosarcoma can sometimes mimic other benign and malignant lesions, thereby presenting a difficult differential diagnosis.
  • In the two cases of cutaneous angiosarcoma presented herein, extensive foamy cell alteration of tumor cells resembled a reactive xanthogranulomatous process.
  • Foamy cell angiosarcoma is an unusual and deceptively benign morphologic variant of cutaneous angiosarcoma.
  • [MeSH-major] Foam Cells / pathology. Granuloma / pathology. Head and Neck Neoplasms / pathology. Hemangiosarcoma / pathology. Skin Neoplasms / pathology. Xanthomatosis / pathology
  • [MeSH-minor] Aged. Diagnosis, Differential. Forehead / pathology. Humans. Male. Shoulder / pathology. Young Adult

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  • (PMID = 20175826.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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34. Lang EK, Rudman E, Colon I, Macchia RJ: Hematuria: the presenting symptom of an angiosarcoma of the inferior vena cava. J Urol; 2009 Nov;182(5):2470
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hematuria: the presenting symptom of an angiosarcoma of the inferior vena cava.
  • [MeSH-major] Hemangiosarcoma / complications. Hemangiosarcoma / diagnosis. Hematuria / etiology. Neoplasms, Multiple Primary / complications. Neoplasms, Multiple Primary / diagnosis. Vascular Neoplasms / complications. Vascular Neoplasms / diagnosis. Vena Cava, Inferior
  • [MeSH-minor] Adult. Humans. Male

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  • (PMID = 19765748.001).
  • [ISSN] 1527-3792
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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35. Al-Abbadi MA, Almasri NM, Al-Quran S, Wilkinson EJ: Cytokeratin and epithelial membrane antigen expression in angiosarcomas: an immunohistochemical study of 33 cases. Arch Pathol Lab Med; 2007 Feb;131(2):288-92
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  • [Title] Cytokeratin and epithelial membrane antigen expression in angiosarcomas: an immunohistochemical study of 33 cases.
  • CONTEXT: Expression of epithelial cell markers can occur in mesenchymal tumors and has been reported in angiosarcomas with variable frequency.
  • OBJECTIVE: To determine the expression of cytokeratin and epithelial membrane antigen in angiosarcoma.
  • DESIGN: To address this issue, 33 well-documented cases of angiosarcomas were retrieved from the archival material of Shands Hospital at the University of Florida, Gainesville, and Jackson Memorial Hospital at the University of Miami, Miami, Florida.
  • CONCLUSION: Cytokeratin and epithelial membrane antigen immunoreactivity in angiosarcomas is infrequent but may be encountered.
  • [MeSH-major] Biomarkers, Tumor / analysis. Hemangiosarcoma / pathology. Keratins / metabolism. Mucin-1 / metabolism
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Child, Preschool. Female. Humans. Immunohistochemistry. Male. Middle Aged. Retrospective Studies

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  • (PMID = 17284115.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Mucin-1; 68238-35-7 / Keratins
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36. Kaushik M, Alla VM, Pasupuleti S, Hunter C, Shatat L, Hunter WJ: Cardiac angiosarcoma and recurrent pericardial effusion. South Med J; 2010 Aug;103(8):849-50
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  • [Title] Cardiac angiosarcoma and recurrent pericardial effusion.
  • [MeSH-major] Heart Neoplasms / complications. Hemangiosarcoma / complications. Pericardial Effusion / etiology
  • [MeSH-minor] Adult. Echocardiography. Humans. Magnetic Resonance Imaging. Male. Recurrence

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  • (PMID = 20622718.001).
  • [ISSN] 1541-8243
  • [Journal-full-title] Southern medical journal
  • [ISO-abbreviation] South. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
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37. Ducimetière F, Lurkin A, Ranchère-Vince D, Decouvelaere AV, Isaac S, Claret-Tournier C, Suignard Y, Salameire D, Cellier D, Alberti L, Bringuier PP, Blay JY, Ray-Coquard I: [Incidence rate, epidemiology of sarcoma and molecular biology. Preliminary results from EMS study in the Rhône-Alpes region]. Bull Cancer; 2010 Jun;97(6):629-41
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  • [Title] [Incidence rate, epidemiology of sarcoma and molecular biology. Preliminary results from EMS study in the Rhône-Alpes region].
  • Sarcomas comprise a heterogeneous group of mesenchymal neoplasms.
  • They can be grouped into 3 general categories, soft tissue sarcoma, visceral and primary bone sarcoma, which have different staging and treatment approaches.
  • Soft tissue sarcomas are typically classified on the basis of genetic alterations and light-microscopic examination of hematoxylin-eosin-stained tissue, in which recognizable morphological characteristics of normal tissues are identified.
  • Sarcomas are further characterized by histologic grade.
  • This review includes a discussion of both soft tissue sarcomas (unclassified sarcoma, liposarcoma, leiomyosarcoma, synovial sarcoma, dermatofibrosarcoma protuberans, angiosarcoma, Kaposi sarcoma, gastrointestinal stromal tumor, rhabdomyosarcoma, ...) and primary bone sarcomas (osteosarcoma, Ewing sarcoma and chondrosarcoma).
  • The approach to a patient with a sarcoma begins with a biopsy that obtains adequate tissue for diagnosis without interfering with subsequent optimal definitive surgery.
  • Subsequent treatment depends on the specific type of sarcoma.
  • Because sarcomas are relatively uncommon yet comprise a wide variety of different entities, second opinion was systematically performed for all included cases.
  • [MeSH-major] Bone Neoplasms / epidemiology. Sarcoma / epidemiology. Soft Tissue Neoplasms / epidemiology
  • [MeSH-minor] Adult. Child. Female. France / epidemiology. Humans. Incidence. Male. Risk Factors


38. Styring E, Fernebro J, Jönsson PE, Ehinger A, Engellau J, Rissler P, Rydholm A, Nilbert M, Vult von Steyern F: Changing clinical presentation of angiosarcomas after breast cancer: from late tumors in edematous arms to earlier tumors on the thoracic wall. Breast Cancer Res Treat; 2010 Aug;122(3):883-7
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  • [Title] Changing clinical presentation of angiosarcomas after breast cancer: from late tumors in edematous arms to earlier tumors on the thoracic wall.
  • Angiosarcoma is a rare complication of breast cancer treatment.
  • In order to define predictors, clinical presentation, and outcome, we characterized a population-based 50-year cohort of angiosarcomas after breast cancer.
  • Clinical data were collected from all females with previous breast cancer who developed angiosarcomas/lymphangiosarcomas on the thoracic wall/upper extremity between 1958 and 2008 in the Southern Swedish health care region.
  • In total, 31 angiosarcomas developed at a median age of 71 years.
  • The patients formed two distinct groups; 14 females treated for breast cancer with radical mastectomy and radiotherapy 1949-1988 developed angiosarcomas in edematous arms (Stewart-Treves syndrome) after median 11 years, and 17 females treated by segmental resection, anti-hormonal treatment and radiotherapy 1980-2005 developed angiosarcomas in the irradiated field on the thoracic wall after median 7.3 years.
  • In this population-based cohort, the early angiosarcomas developed in edematous arms after radical mastectomies, whereas more recent cases occurred after a shorter time period in the irradiated fields following breast conserving surgery.
  • We conclude that the clinical presentation of angiosarcomas has changed, parallel with altered treatment principles for breast cancer.
  • [MeSH-major] Arm. Breast Neoplasms / therapy. Edema / etiology. Hemangiosarcoma / etiology. Neoplasm Recurrence, Local / etiology. Neoplasms, Second Primary / etiology. Thoracic Wall / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Cohort Studies. Female. Humans. Middle Aged. Prognosis

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  • (PMID = 20087653.001).
  • [ISSN] 1573-7217
  • [Journal-full-title] Breast cancer research and treatment
  • [ISO-abbreviation] Breast Cancer Res. Treat.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
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39. Penel N, Bui BN, Bay JO, Cupissol D, Ray-Coquard I, Piperno-Neumann S, Kerbrat P, Fournier C, Taieb S, Jimenez M, Isambert N, Peyrade F, Chevreau C, Bompas E, Brain EG, Blay JY: Phase II trial of weekly paclitaxel for unresectable angiosarcoma: the ANGIOTAX Study. J Clin Oncol; 2008 Nov 10;26(32):5269-74
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  • [Title] Phase II trial of weekly paclitaxel for unresectable angiosarcoma: the ANGIOTAX Study.
  • PURPOSE: The objective of this phase II trial was to assess the efficacy and toxicity of weekly paclitaxel for patients with metastatic or unresectable angiosarcoma.
  • Three patients with locally advanced breast angiosarcoma presented partial response, which enabled a secondary curative-intent surgery with complete histologic response in two cases.
  • [MeSH-major] Antineoplastic Agents, Phytogenic / administration & dosage. Breast Neoplasms / drug therapy. Head and Neck Neoplasms / drug therapy. Hemangiosarcoma / drug therapy. Paclitaxel / administration & dosage. Scalp. Skin Neoplasms / drug therapy. Soft Tissue Neoplasms / drug therapy
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Disease-Free Survival. Drug Administration Schedule. Female. France / epidemiology. Humans. Infusions, Intravenous. Kaplan-Meier Estimate. Male. Middle Aged. Neoplasm Metastasis. Time Factors. Treatment Outcome

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  • (PMID = 18809609.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; P88XT4IS4D / Paclitaxel
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40. Kiluk JV, Yeh KA: Primary angiosarcoma of the breast. Breast J; 2005 Nov-Dec;11(6):517-8
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  • [Title] Primary angiosarcoma of the breast.
  • [MeSH-major] Breast Neoplasms / pathology. Hemangiosarcoma / pathology
  • [MeSH-minor] Adult. Female. Humans. Mastectomy, Modified Radical

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  • (PMID = 16297124.001).
  • [ISSN] 1075-122X
  • [Journal-full-title] The breast journal
  • [ISO-abbreviation] Breast J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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41. Moses KA, Tillett JW, Master VA: Primary penile angiosarcoma in a patient with AIDS: a case report. AIDS; 2007 Nov 12;21(17):2355-6
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  • [Title] Primary penile angiosarcoma in a patient with AIDS: a case report.
  • [MeSH-major] Acquired Immunodeficiency Syndrome / complications. Hemangiosarcoma / virology. Penile Neoplasms / virology
  • [MeSH-minor] Adult. Humans. Male. Sarcoma, Kaposi / complications

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  • (PMID = 18090289.001).
  • [ISSN] 0269-9370
  • [Journal-full-title] AIDS (London, England)
  • [ISO-abbreviation] AIDS
  • [Language] eng
  • [Publication-type] Case Reports; Letter; Review
  • [Publication-country] England
  • [Number-of-references] 11
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42. Kulkarni MP, Agashe SR, Singh RV, Sulhyan KR: Hepatic angiosarcoma arising in an adult mesenchymal hamartoma. Indian J Pathol Microbiol; 2010 Apr-Jun;53(2):322-4
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  • [Title] Hepatic angiosarcoma arising in an adult mesenchymal hamartoma.
  • Embryonal (undifferentiated) sarcomas arising in mesenchymal hamartoma are on record but cases of hepatic angiosarcoma (AS) arising in mesenchymal hamartoma (MH) of the liver are extremely rare.
  • [MeSH-major] Hamartoma / complications. Hamartoma / diagnosis. Hemangiosarcoma / diagnosis. Hemangiosarcoma / pathology. Liver Neoplasms / diagnosis. Liver Neoplasms / pathology
  • [MeSH-minor] Abdomen / pathology. Abdomen / ultrasonography. Histocytochemistry. Humans. Male. Microscopy. Young Adult

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  • (PMID = 20551545.001).
  • [ISSN] 0974-5130
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] India
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43. Wang ZS, Zhan N, Xiong CL, Li H: Primary epithelioid angiosarcoma of the male breast: report of a case. Surg Today; 2007;37(9):782-6
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  • [Title] Primary epithelioid angiosarcoma of the male breast: report of a case.
  • We report a case of primary epithelioid angiosarcoma of the male breast.
  • Histopathological examination and immunohistochemical analysis confirmed a diagnosis of primary epithelioid angiosarcoma of the male breast, without axillary lymph node metastasis.
  • [MeSH-major] Breast Neoplasms, Male / pathology. Hemangiosarcoma / pathology. Neoplasms, Glandular and Epithelial / pathology
  • [MeSH-minor] Adult. Humans. Immunohistochemistry. Male. Sex Factors

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  • (PMID = 17713733.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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44. Yu RS, Chen Y, Jiang B, Wang LH, Xu XF: Primary hepatic sarcomas: CT findings. Eur Radiol; 2008 Oct;18(10):2196-205
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  • [Title] Primary hepatic sarcomas: CT findings.
  • Primary hepatic sarcomas are rare tumors that are difficult to diagnose clinically.
  • Different primary hepatic sarcomas may have different clinical, morphologic, and radiological features.
  • In this pictorial review, we summarized computed tomography (CT) findings of some relatively common types of hepatic sarcomas, including angiosarcoma, epithelioid hemangioendothelioma (EHE), liposarcoma, undifferentiated embryonal sarcoma (UES), leiomyosarcoma, malignant fibrous histiocytoma (MFH), and carcinosarcoma (including cystadenocarcinosarcoma).
  • The advent of CT has allowed earlier detection of primary hepatic sarcomas as well as more accurate diagnosis and characterization.
  • In addition, we briefly discuss the MRI findings and diagnostic value of primary hepatic sarcomas.
  • [MeSH-major] Liver / diagnostic imaging. Liver Neoplasms / diagnostic imaging. Sarcoma / diagnostic imaging. Tomography, X-Ray Computed / methods
  • [MeSH-minor] Adult. Aged. Child. Female. Humans. Male. Middle Aged

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  • (PMID = 18463872.001).
  • [ISSN] 0938-7994
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 53
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45. Takeuchi I, Kawaguchi T, Kimura Y, Kojima J, Shimamura H, Shimizu N, Izumi T: Primary cardiac osteosarcoma in a young man with severe congestive heart failure. Intern Med; 2007;46(10):649-51
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  • Among most malignant tumors, angiosarcoma, leiomyosarcoma, and mesothelioma occupy the majority.
  • [MeSH-minor] Adult. Dyspnea / etiology. Echocardiography. Humans. Male


46. Tavora F, Montgomery E, Epstein JI: A series of vascular tumors and tumorlike lesions of the bladder. Am J Surg Pathol; 2008 Aug;32(8):1213-9
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  • We identified 13 lesions that included 3 hemangiomas, 3 intravascular papillary endothelial hyperplasias (Masson vegetant hemangioendotheliomas), 2 arteriovenous malformations (AVMs), 1 epithelioid hemangioendothelioma (EHE), and 4 angiosarcomas.
  • One of the angiosarcomas was associated with conventional high-grade urothelial carcinoma (sarcomatoid carcinoma).
  • There was no statistical difference among the various lesions in terms of age, although angiosarcomas tended to arise in older patients (mean 71 y vs. 60 y of the remainder).
  • All cases of angiosarcoma and EHE involved the muscularis propria.
  • Two of four patients with angiosarcoma had a history of prior radiation therapy and all 4 were dead of disease at 6 months.
  • Angiosarcomas measured 3, 4.5, 5, and 5.8 cm in greatest diameter at cystoscopy.
  • Papillary endothelial hyperplasia occurs in the bladder and must be differentiated from angiosarcoma, which has a rapidly fatal outcome.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Arteriovenous Malformations / pathology. Endothelium, Vascular / pathology. Female. Hemangioendothelioma / pathology. Hemangioendothelioma, Epithelioid / pathology. Hemangioma / pathology. Hemangiosarcoma / pathology. Hematuria / etiology. Humans. Hyperplasia. Male. Middle Aged. Neoplasm Invasiveness. Prognosis. Retrospective Studies

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  • (PMID = 18580491.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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47. Sher T, Hennessy BT, Valero V, Broglio K, Woodward WA, Trent J, Hunt KK, Hortobagyi GN, Gonzalez-Angulo AM: Primary angiosarcomas of the breast. Cancer; 2007 Jul 1;110(1):173-8
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  • [Title] Primary angiosarcomas of the breast.
  • BACKGROUND: The purpose of the study was to describe the clinicopathologic characteristics and clinical outcomes of patients with primary breast angiosarcoma.
  • METHODS: The institutional database was searched to identify breast angiosarcoma patients seen between 1965 and 2002.
  • CONCLUSIONS: Breast angiosarcoma is frequently advanced at diagnosis and has a tendency for local-regional recurrence.
  • [MeSH-major] Breast Neoplasms / pathology. Hemangiosarcoma / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Female. Follow-Up Studies. Humans. Lymphatic Metastasis. Middle Aged. Neoplasm Staging. Receptors, Estrogen / metabolism. Receptors, Progesterone / metabolism. Survival Analysis

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  • [Copyright] Copyright (c) 2007 American Cancer Society.
  • (PMID = 17541936.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / L30 CA123630; United States / NCI NIH HHS / CA / L30 CA123630-01; United States / NCI NIH HHS / CA / L30 CA123630-02
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
  • [Other-IDs] NLM/ NIHMS283619; NLM/ PMC4329779
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48. Loya AC, Prayaga AK, Arora A, Sundaram C, Rao IS, Uppin SG, Raju GS, Surath A, Rajappa RS: Lymph node metastasis of soft tissue tumors: a cytomorphologic study. Acta Cytol; 2007 Mar-Apr;51(2):153-60
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  • STTs commonly involving lymph nodes were rhabdomyosarcoma and extraskeletal Ewing's/primitive neuroectodermal tumor (PNET); other rare tumors included malignant granular cell tumor, epithelioid hemangioendothelioma, mediastinal ganglioneuroblastoma, angiosarcoma and epithelioid sarcoma.
  • [MeSH-major] Lymph Nodes / pathology. Lymphatic Metastasis / pathology. Rhabdomyosarcoma / secondary. Sarcoma, Ewing / secondary. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Biopsy, Fine-Needle / standards. Biopsy, Fine-Needle / statistics & numerical data. Biopsy, Fine-Needle / trends. Child. Child, Preschool. Diagnosis, Differential. Diagnostic Errors / prevention & control. Female. Humans. Male. Middle Aged. Predictive Value of Tests. Prevalence. Prognosis. Prospective Studies. Retrospective Studies

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  • (PMID = 17425195.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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49. Nelson BL, Thompson LD: Sinonasal tract angiosarcoma: a clinicopathologic and immunophenotypic study of 10 cases with a review of the literature. Head Neck Pathol; 2007 Sep;1(1):1-12
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  • [Title] Sinonasal tract angiosarcoma: a clinicopathologic and immunophenotypic study of 10 cases with a review of the literature.
  • BACKGROUND: Primary sinonasal tract angiosarcoma are rare tumors that are frequently misclassified, resulting in inappropriate clinical management.
  • MATERIALS AND METHODS: Ten patients with sinonasal tract angiosarcoma were retrospectively retrieved from the Otorhinolaryngic Registry of the Armed Forces Institute of Pathology.
  • The principle differential diagnosis includes granulation tissue, lobular capillary hemangioma (pyogenic granuloma), and Kaposi's sarcoma.
  • CONCLUSIONS: Sinonasal tract angiosarcoma is a rare tumor, frequently presenting in middle-aged patients as a large mass usually involving the nasal cavity with characteristic histomorphologic and immunophenotypic features.
  • Sinonasal tract angiosarcoma will often have a poor prognosis making appropriate separation from other conditions important.
  • [MeSH-major] Hemangiosarcoma / pathology. Nasal Cavity / pathology. Paranasal Sinus Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / metabolism. Diagnosis, Differential. Fatal Outcome. Female. Granulation Tissue / pathology. Granuloma, Pyogenic / diagnosis. Humans. Male. Middle Aged. Prognosis. Sarcoma, Kaposi / diagnosis. Young Adult

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  • (PMID = 20614274.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ PMC2807511
  • [Keywords] NOTNLM ; Angiosarcoma / Differential diagnosis / Hemangioma / Immunohistochemistry / Nasal cavity / Prognosis / Sarcoma / Sinonasal tract / Survival / Vascular
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50. Deyrup AT, McKenney JK, Tighiouart M, Folpe AL, Weiss SW: Sporadic cutaneous angiosarcomas: a proposal for risk stratification based on 69 cases. Am J Surg Pathol; 2008 Jan;32(1):72-7
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  • [Title] Sporadic cutaneous angiosarcomas: a proposal for risk stratification based on 69 cases.
  • Angiosarcomas have traditionally been considered high-grade lesions for which histologic features and grading have played no role in prognostication and, consequently, they have been excluded from the American Joint Committee on Cancer staging system.
  • We have, therefore, analyzed 69 cutaneous angiosarcomas seen in consultation and not associated with lymphedema or prior radiation therapy to determine if a combination of histologic and clinical parameters could be used to differentiate indolent from aggressive tumors.
  • In conclusion, we report that a combination of clinical and histologic features allows stratification of angiosarcoma patients into 2 risk groups that are strongly associated with marked differences in clinical course.
  • [MeSH-major] Hemangiosarcoma / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adult. Age Factors. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Risk Factors. Survival Analysis

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  • (PMID = 18162773.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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51. Sudzinski J, Thomas F, Berthout A, Gonthier MF, Lumbroso-Le Rouic L, Milazzo S: [Conjunctival Kaposi sarcoma]. J Fr Ophtalmol; 2009 Feb;32(2):151-5
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  • [Title] [Conjunctival Kaposi sarcoma].
  • Kaposi sarcoma is rare and occurs in four forms (classic, endemic, post-transplant and epidemic), which all have the same histological appearance associated with the same viral agent: human herpes virus type 8 (HHV-8).
  • We present the case of a 34-year-old woman with conjunctival Kaposi angiosarcoma, with rare bulbar location associated with superior palpebral telangiectases against a rare immunodepression syndrome (common variable immunodeficiency).
  • [MeSH-major] Conjunctival Neoplasms / pathology. Sarcoma, Kaposi / pathology
  • [MeSH-minor] Adult. Female. Humans

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  • (PMID = 20579478.001).
  • [ISSN] 1773-0597
  • [Journal-full-title] Journal français d'ophtalmologie
  • [ISO-abbreviation] J Fr Ophtalmol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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52. Gupta A, Saifuddin A, Briggs TW, Flanagan AM: Subperiosteal hemangioendothelioma of the femur. Skeletal Radiol; 2006 Oct;35(10):793-6
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  • Primary neoplastic vascular lesions of bone are rare, and include haemangiomas, haemangioendothelioma, epithelioid haemangioendothelioma and angiosarcoma.
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. Tomography, X-Ray Computed

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  • (PMID = 16421750.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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53. Cronin H, Mowad C, Ferringer T: Large nodular plaque on leg in the setting of chronic lymphedema--quiz case. Angiosarcoma in the setting of familial lymphedema. Arch Dermatol; 2010 Mar;146(3):337-42
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  • [Title] Large nodular plaque on leg in the setting of chronic lymphedema--quiz case. Angiosarcoma in the setting of familial lymphedema.
  • [MeSH-major] Hemangiosarcoma / diagnosis. Lymphedema / complications. Skin Neoplasms / diagnosis
  • [MeSH-minor] Adult. Biopsy. Chronic Disease. Diagnosis, Differential. Humans. Leg. Male

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  • (PMID = 20231513.001).
  • [ISSN] 1538-3652
  • [Journal-full-title] Archives of dermatology
  • [ISO-abbreviation] Arch Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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54. Catalano O, Sandomenico F, Raso MM, Siani A: Real-time, contrast-enhanced sonography: a new tool for detecting active bleeding. J Trauma; 2005 Oct;59(4):933-9
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  • These included spleen injury (n = 8), liver injury (n = 3), kidney injury (n = 1), abdominal aortic aneurysm rupture (n = 5), splenic angiosarcoma rupture (n = 1), postsurgical bleeding after abdominal aortic aneurysm repair (n = 1), and postsplenectomy bleeding (n = 1).
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Female. Humans. Male. Middle Aged

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  • (PMID = 16374284.001).
  • [ISSN] 0022-5282
  • [Journal-full-title] The Journal of trauma
  • [ISO-abbreviation] J Trauma
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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55. De Smet S, Vandermeeren L, Christiaens MR, Samson I, Stas M, Van Limbergen E, De Wever I: Radiation-induced sarcoma: analysis of 46 cases. Acta Chir Belg; 2008 Sep-Oct;108(5):574-9
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  • [Title] Radiation-induced sarcoma: analysis of 46 cases.
  • A retrospective analysis was performed of 46 cases of sarcoma treated in our institution between 1989 and 2007 that occurred in a previously irradiated area.
  • The interval between irradiation and the diagnosis of sarcoma ranged from 1 to 54 years (median 15 y).
  • Angiosarcoma and sarcoma non-otherwise-specified were the most common histological types.
  • Stage and location of the sarcoma were other prognostic factors.
  • [MeSH-major] Neoplasms, Radiation-Induced / mortality. Neoplasms, Radiation-Induced / surgery. Sarcoma / mortality. Sarcoma / surgery
  • [MeSH-minor] Abdominal Neoplasms / mortality. Abdominal Neoplasms / pathology. Abdominal Neoplasms / surgery. Adult. Aged. Aged, 80 and over. Extremities. Female. Head and Neck Neoplasms / mortality. Head and Neck Neoplasms / pathology. Head and Neck Neoplasms / surgery. Humans. Lung Neoplasms / mortality. Lung Neoplasms / pathology. Lung Neoplasms / surgery. Male. Middle Aged. Neoplasm Metastasis. Pelvic Neoplasms / mortality. Pelvic Neoplasms / pathology. Pelvic Neoplasms / surgery. Retrospective Studies. Thoracic Neoplasms / mortality. Thoracic Neoplasms / pathology. Thoracic Neoplasms / surgery. Young Adult

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  • (PMID = 19051469.001).
  • [ISSN] 0001-5458
  • [Journal-full-title] Acta chirurgica Belgica
  • [ISO-abbreviation] Acta Chir. Belg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Belgium
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56. Schwab J, Haack G, Wünsch PH, Bär I, Zahn R: Cardiac angiosarcoma: case report and review of the literatur : R. R. Brandt, R. Arnold, R.M. Bohle, T. Dill, C.W. Hamm; Z Kardiol 94:824-828 (2005). Clin Res Cardiol; 2006 Jun;95(6):351-2; author reply 352-3
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  • [Title] Cardiac angiosarcoma: case report and review of the literatur : R. R. Brandt, R. Arnold, R.M. Bohle, T. Dill, C.W. Hamm; Z Kardiol 94:824-828 (2005).
  • [MeSH-major] Heart Neoplasms / pathology. Hemangiosarcoma / pathology. Magnetic Resonance Imaging
  • [MeSH-minor] Adult. Humans. Male

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  • [CommentOn] Z Kardiol. 2005 Dec;94(12):824-8 [16382384.001]
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  • (PMID = 16741594.001).
  • [ISSN] 1861-0684
  • [Journal-full-title] Clinical research in cardiology : official journal of the German Cardiac Society
  • [ISO-abbreviation] Clin Res Cardiol
  • [Language] eng
  • [Publication-type] Case Reports; Comment; Letter
  • [Publication-country] Germany
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57. Yanada M, Shimada J, Ito K, Terauchi K, Shimomura M: [Cardiac angiosarcoma with diagnostic difficulty]. Kyobu Geka; 2007 Dec;60(13):1148-51
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  • [Title] [Cardiac angiosarcoma with diagnostic difficulty].
  • We report a case of cardiac angiosarcoma of the right atrium.
  • Pathohistologically, the tumor was diagnosed as a cardiac angiosarcoma.
  • [MeSH-major] Heart Neoplasms / diagnosis. Hemangiosarcoma / diagnosis
  • [MeSH-minor] Adult. Biopsy. CA-125 Antigen / blood. Female. Heart Atria. Humans

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  • (PMID = 18078079.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / CA-125 Antigen
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58. Kar A, Mukhopadhyay D, Das SS, Swain NN, Das BM, Nayak M, Rath J, Satpathy S: Cytodiagnosis of angiosarcoma of breast. Indian J Pathol Microbiol; 2008 Jul-Sep;51(3):427-9
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  • [Title] Cytodiagnosis of angiosarcoma of breast.
  • The case was diagnosed by preoperative cytology as angiosarcoma of breast, after which, she underwent modified radical mastectomy.
  • Angiosarcoma of breast is uncommon with extremely bad prognosis.
  • [MeSH-major] Breast Neoplasms / diagnosis. Hemangiosarcoma / diagnosis
  • [MeSH-minor] Adult. Cytodiagnosis. Female. Humans. Mastectomy

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  • (PMID = 18723981.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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59. Weitz J, Klimstra DS, Cymes K, Jarnagin WR, D'Angelica M, La Quaglia MP, Fong Y, Brennan MF, Blumgart LH, Dematteo RP: Management of primary liver sarcomas. Cancer; 2007 Apr 1;109(7):1391-6
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  • [Title] Management of primary liver sarcomas.
  • BACKGROUND: Primary hepatic sarcoma is a rare entity.
  • METHODS: Between January 1981 and December 2004, 30 patients with primary sarcoma of the liver and 5 patients with primary carcinosarcoma of the liver were treated.
  • RESULTS: Of the 30 patients with primary hepatic sarcoma (10 epithelioid hemangioendothelioma, 5 embryonal sarcoma, 5 angiosarcoma, 3 solitary fibrous tumor, and 7 other types), 11 underwent R0-resection and had a 5-year disease-specific survival of 64%.
  • Of these 11 patients, 4 had low-grade sarcoma and have not developed tumor recurrence.
  • In the group of 7 patients with high-grade sarcomas who underwent R0-resection, both patients with angiosarcoma died within 11 months, whereas the 5 patients with embryonal sarcoma had a 5-year disease-free and disease-specific survival of 80%.
  • CONCLUSIONS: The outcome of patients with primary hepatic sarcoma depends primarily on tumor histology and the ability to achieve complete tumor resection.
  • [MeSH-major] Liver Neoplasms / therapy. Sarcoma / therapy
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinosarcoma / therapy. Child. Female. Fibrosarcoma / therapy. Hemangioendothelioma, Epithelioid / therapy. Hemangiosarcoma / therapy. Humans. Leiomyosarcoma / therapy. Male. Middle Aged. Prognosis. Prospective Studies. Survival Rate. Treatment Outcome

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  • [Copyright] (c) 2007 American Cancer Society.
  • (PMID = 17315167.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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60. Syed SP, Martin AM, Haupt HM, Arenas-Elliot CP, Brooks JJ: Angiostatin receptor annexin II in vascular tumors including angiosarcoma. Hum Pathol; 2007 Mar;38(3):508-13
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  • [Title] Angiostatin receptor annexin II in vascular tumors including angiosarcoma.
  • Thirty-eight (38) vascular tumors tested included: hemangiomas - capillary [4], cavernous [6], lobular capillary [6], intramuscular hemangioma [3], spindle cell [1], and epithelioid hemangioma [4]; epithelioid hemangioendothelioma [3]; angiosarcoma [7], 4 of which were epithelioid; and angiolipomas [4].
  • Epithelioid angiosarcomas showed predominantly membranous staining.
  • To our knowledge this is the first demonstration of an angiostatin receptor (ANX2) in vascular endothelial tumors including angiosarcoma.
  • ANX2 reactivity may be the basis of treatment for a variety of benign tumors, especially in pediatric patients, and may offer a new and potentially less toxic therapy for angiosarcoma.
  • [MeSH-major] Annexin A2 / metabolism. Hemangioma / metabolism. Hemangiosarcoma / metabolism. Neoplasms, Vascular Tissue / metabolism
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged

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  • (PMID = 17239928.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Annexin A2
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61. DeMartelaere SL, Roberts D, Burgess MA, Morrison WH, Pisters PW, Sturgis EM, Ho V, Esmaeli B: Neoadjuvant chemotherapy-specific and overall treatment outcomes in patients with cutaneous angiosarcoma of the face with periorbital involvement. Head Neck; 2008 May;30(5):639-46
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  • [Title] Neoadjuvant chemotherapy-specific and overall treatment outcomes in patients with cutaneous angiosarcoma of the face with periorbital involvement.
  • BACKGROUND: Recent isolated case reports have suggested a potential role for neoadjuvant chemotherapy in patients with angiosarcoma.
  • The goal of this report was to investigate the overall treatment outcomes and the neoadjuvant chemotherapy-specific outcomes in patients with cutaneous angiosarcoma of the face with periorbital involvement.
  • METHODS: Our tumor database was searched for patients with angiosarcoma and periorbital involvement seen at our institution between 1981 and 2005.
  • CONCLUSION: On the basis of this series, the authors conclude that neoadjuvant chemotherapy for periorbital angiosarcoma is a potentially attractive option and in some patients may obviate the need for major surgery, thereby preserving the eye and/or ocular adnexal structures.
  • [MeSH-major] Eyelid Neoplasms / therapy. Facial Neoplasms / therapy. Hemangiosarcoma / therapy. Neoadjuvant Therapy. Skin Neoplasms / therapy
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Chemotherapy, Adjuvant. Disease-Free Survival. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Radiotherapy, Adjuvant. Retrospective Studies. Survival Analysis

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  • (PMID = 18213722.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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62. Hoti E, Adam R: Liver transplantation for primary and metastatic liver cancers. Transpl Int; 2008 Dec;21(12):1107-17
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  • There is no controversy about the fact that liver transplantation for HCC in the adult population yields good results for patients whose tumour masses do not exceed the Milan criteria.
  • Epithelioid hemangioendothelioma is also an appropriate indication for liver transplantation, even in the presence of extrahepatic metastases, unlike angiosarcoma which is associated with a very poor survival and considered as a contraindication.
  • [MeSH-minor] Bile Duct Neoplasms / surgery. Carcinoma, Hepatocellular / pathology. Carcinoma, Hepatocellular / surgery. Cholangiocarcinoma / surgery. Colorectal Neoplasms / pathology. Hemangioendothelioma / surgery. Hemangiosarcoma / surgery. Humans. Neoplasm Metastasis. Neoplasm Staging. Neuroendocrine Tumors / surgery. Survival Analysis. Survivors. Treatment Outcome

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  • (PMID = 18713148.001).
  • [ISSN] 0934-0874
  • [Journal-full-title] Transplant international : official journal of the European Society for Organ Transplantation
  • [ISO-abbreviation] Transpl. Int.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 75
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63. Malani AK, Hindupur M, Gupta C: Vascular tumour blush of cardiac angiosarcoma on coronary angiography. Heart; 2007 Oct;93(10):1237
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  • [Title] Vascular tumour blush of cardiac angiosarcoma on coronary angiography.
  • [MeSH-major] Heart Neoplasms / radiography. Hemangiosarcoma / radiography
  • [MeSH-minor] Adult. Coronary Angiography. Female. Heart Atria. Humans

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  • (PMID = 17890700.001).
  • [ISSN] 1468-201X
  • [Journal-full-title] Heart (British Cardiac Society)
  • [ISO-abbreviation] Heart
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2000942
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64. Lvoff NM, Leung JW: Case of the season: primary angiosarcoma of the breast: correlative imaging and pathology. Semin Roentgenol; 2007 Oct;42(4):208-10
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  • [Title] Case of the season: primary angiosarcoma of the breast: correlative imaging and pathology.
  • [MeSH-major] Breast Neoplasms / diagnosis. Diagnostic Imaging. Hemangiosarcoma / diagnosis
  • [MeSH-minor] Adult. Contrast Media. Diagnosis, Differential. Female. Humans. Mastectomy, Radical

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  • (PMID = 17919522.001).
  • [ISSN] 0037-198X
  • [Journal-full-title] Seminars in roentgenology
  • [ISO-abbreviation] Semin Roentgenol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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65. Schlemmer M, Reichardt P, Verweij J, Hartmann JT, Judson I, Thyss A, Hogendoorn PC, Marreaud S, Van Glabbeke M, Blay JY: Paclitaxel in patients with advanced angiosarcomas of soft tissue: a retrospective study of the EORTC soft tissue and bone sarcoma group. Eur J Cancer; 2008 Nov;44(16):2433-6
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  • [Title] Paclitaxel in patients with advanced angiosarcomas of soft tissue: a retrospective study of the EORTC soft tissue and bone sarcoma group.
  • RATIONALE: Angiosarcomas of soft tissue represent a heterogenous group of rare sarcomas with specific clinical behaviour and risk factors.
  • Paclitaxel appears to induce tumour control in a higher proportion of patients with angiosarcoma, as compared to other sarcomas.
  • METHOD: Clinical data from patients with angiosarcomas of soft tissue treated with single agent paclitaxel were collected from the centres of the soft tissue and bone sarcoma group of EORTC, using a standardised data collection form.
  • Primary angiosarcomas were located in scalp and face in 8 patients (25%) and at other primary sites in 24 patients (75%).
  • Eleven (34%) patients had been irradiated before as treatment for angiosarcoma.
  • In 8 (25%) patients, the angiosarcoma occurred at sites of prior radiation therapy for other malignancies.
  • The response rate was 62% (21/32) in the whole series, 75% (6/8) in scalp angiosarcomas and 58% (14/24) in other primary sites.
  • For the face/scalp group it was 9.5 months, and for patients with angiosarcomas at other sites it was 7.0 months, respectively.
  • CONCLUSION: Paclitaxel was found to be an active agent in angiosarcoma of soft tissue in this retrospective analysis.
  • [MeSH-major] Antineoplastic Agents, Phytogenic / therapeutic use. Hemangiosarcoma / drug therapy. Paclitaxel / therapeutic use. Soft Tissue Neoplasms / drug therapy
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Facial Neoplasms / drug therapy. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / drug therapy. Retrospective Studies. Scalp. Skin Neoplasms / drug therapy. Young Adult


66. de Bree R, van der Waal I, de Bree E, Leemans CR: Management of adult soft tissue sarcomas of the head and neck. Oral Oncol; 2010 Nov;46(11):786-90
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  • [Title] Management of adult soft tissue sarcomas of the head and neck.
  • Adult soft tissue sarcoma of the head and neck are rare and represent a heterogeneous group of tumours of different histological variants.
  • Malignant fibrous histiocytoma, fibrosarcoma, angiosarcoma and malignant peripheral nerve sheath tumour are the most frequently found sarcoma types in the head and neck.
  • The management of soft tissue sarcomas in the head and neck is primarily surgical.
  • Since it is difficult to obtain wide margins during surgical treatment in head and neck sarcomas, because of anatomic constraints, most patients undergo post-operative irradiation.
  • With further insight into the biology of soft tissue sarcoma, modern imaging techniques and new treatment options, we will most certainly be able to improve clinical outcome in patients with soft tissue sarcoma in the upcoming years.
  • [MeSH-major] Head and Neck Neoplasms / surgery. Sarcoma / surgery. Soft Tissue Neoplasms / surgery
  • [MeSH-minor] Adult. Female. Humans. Male. Prognosis. Treatment Outcome


67. Batzios S, Michalopoulos A, Kaklamanis L, Stathopoulos J, Christopoulou M, Koutantos J, Stathopoulos GP: Angiosarcoma of the heart: case report and review of the literature. Anticancer Res; 2006 Nov-Dec;26(6C):4837-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma of the heart: case report and review of the literature.
  • BACKGROUND: Primary angiosarcoma of the heart is an extremely rare malignant disease.
  • PATIENTS AND METHODS: A 32-year-old female with primary angiosarcoma of the heart at an advanced stage with lung and bone metastases is presented.
  • CONCLUSION: This case of angiosarcoma of the heart is presented because of the extreme rarity of this disease, and its responsiveness to chemotherapy in combination with imatinib and herceptin.
  • [MeSH-major] Heart Neoplasms / pathology. Hemangiosarcoma / pathology
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bone Neoplasms / secondary. Cisplatin / administration & dosage. Epirubicin / administration & dosage. Female. Humans. Ifosfamide / administration & dosage. Lung Neoplasms / secondary

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  • (PMID = 17214349.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 3Z8479ZZ5X / Epirubicin; Q20Q21Q62J / Cisplatin; UM20QQM95Y / Ifosfamide
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68. Soares AB, Altemani A, Furuse C, Demasi AP, Gati C, Nunes N, de Araújo VC: Intravascular papillary endothelial hyperplasia: report of 2 cases and immunohistochemical study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2008 Nov;106(5):708-11
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  • The main significance of the lesion lies in the fact that it may be mistaken for angiosarcoma.
  • [MeSH-minor] Actins / analysis. Adult. Aged. Antigens, CD34 / analysis. Diagnosis, Differential. Female. Fibrillar Collagens / analysis. Hemangiosarcoma / diagnosis. Humans. Hyperplasia / pathology. Immunohistochemistry. Laminin / analysis. Lip Diseases / pathology. Mouth Mucosa / pathology. Mouth Neoplasms / diagnosis. Vimentin / analysis

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  • (PMID = 18929993.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, CD34; 0 / Fibrillar Collagens; 0 / Laminin; 0 / Vimentin
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69. Valbuena JR, Levenback C, Mansfield P, Liu J: Angiosarcoma of the spleen clinically presenting as metastatic ovarian cancer. A case report and review of the literature. Ann Diagn Pathol; 2005 Oct;9(5):289-92
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  • [Title] Angiosarcoma of the spleen clinically presenting as metastatic ovarian cancer. A case report and review of the literature.
  • Primary angiosarcomas of the spleen are rare and almost always fatal.
  • The differential diagnosis includes a variety of benign and malignant vascular proliferations (littoral cell angioma and Kaposi's sarcoma) as well as metastatic tumors.
  • However, histopathologic examination of the specimen showed the tumor to be of a primary angiosarcoma.
  • [MeSH-major] Hemangiosarcoma / pathology. Neoplasms, Second Primary / pathology. Ovarian Neoplasms / pathology. Splenic Neoplasms / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans


70. Katabathina VS, Vikram R, Nagar AM, Tamboli P, Menias CO, Prasad SR: Mesenchymal neoplasms of the kidney in adults: imaging spectrum with radiologic-pathologic correlation. Radiographics; 2010 Oct;30(6):1525-40
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  • Malignant renal tumors of mesenchymal origin include leiomyosarcoma, rhabdomyosarcoma, angiosarcoma, osteosarcoma, synovial sarcoma, fibrosarcoma, malignant fibrous histiocytoma, and solitary fibrous tumor.
  • Although osteosarcoma may demonstrate characteristic dense ossification, most renal sarcomas demonstrate imaging features that are indistinguishable from the more common renal cell carcinoma.
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Humans

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  • [Copyright] © RSNA, 2010.
  • (PMID = 21071373.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
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71. Smigla GR, Lawson DS, Kaemmer DD, Shearer IR: Venous line filtration: a novel technique for cases involving inferior vena caval and right atrial tumor and associated thrombus: a two-case series. Perfusion; 2006 Nov;21(6):391-4
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  • The second case was a 37-year-old male (95 kg, 178 cm, BSA 2.17 m2), who presented with a very large angiosarcoma tumor involving almost the entire right atrium.
  • [MeSH-major] Heart Neoplasms / surgery. Hemangiosarcoma / surgery. Intraoperative Complications / prevention & control. Neoplastic Cells, Circulating. Vena Cava Filters
  • [MeSH-minor] Adult. Cardiopulmonary Bypass / instrumentation. Female. Heart Atria / surgery. Humans. Magnetic Resonance Imaging. Male. Vena Cava, Inferior

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  • (PMID = 17312864.001).
  • [ISSN] 0267-6591
  • [Journal-full-title] Perfusion
  • [ISO-abbreviation] Perfusion
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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72. Wildi JD, Baggstrom MQ, Suresh R, Read W, Fracasso PM, Govindan R: A phase I study of docetaxel and bexarotene. Chemotherapy; 2008;54(2):125-30
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  • Four patients had stable disease as a best response, 3 with non-small-cell lung cancer and 1 with angiosarcoma.
  • [MeSH-minor] Adult. Aged. Drug Administration Schedule. Fatigue / blood. Fatigue / chemically induced. Female. Humans. Male. Middle Aged. Nausea / blood. Nausea / chemically induced. Neoplasms / blood. Neoplasms / drug therapy. Taxoids / administration & dosage. Taxoids / adverse effects. Tetrahydronaphthalenes / administration & dosage. Tetrahydronaphthalenes / adverse effects

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  • (PMID = 18332628.001).
  • [ISSN] 1421-9794
  • [Journal-full-title] Chemotherapy
  • [ISO-abbreviation] Chemotherapy
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA91842
  • [Publication-type] Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Taxoids; 0 / Tetrahydronaphthalenes; 15H5577CQD / docetaxel; A61RXM4375 / bexarotene
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73. Parsons A, Sheehan DJ, Sangueza OP: Retiform hemangioendotheliomas usually do not express D2-40 and VEGFR-3. Am J Dermatopathol; 2008 Feb;30(1):31-3
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  • RH differs from angiosarcoma by lacking cytologic atypia and high mitotic rates.
  • [MeSH-minor] Adolescent. Adult. Aged. Antibodies, Monoclonal. Antibodies, Monoclonal, Murine-Derived. Antigens, CD31 / metabolism. Female. Humans. Immunohistochemistry. Middle Aged

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  • (PMID = 18212541.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Antigens, CD31; 0 / Biomarkers, Tumor; 0 / Sialoglycoproteins; 0 / monoclonal antibody D2-40; EC 2.7.10.1 / Vascular Endothelial Growth Factor Receptor-3
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74. Kikawa Y, Konishi Y, Nakamoto Y, Harada T, Takeo M, Ogata M, Yamamoto M, Usuki N, Toyoshima M, Katsuyama E: Angiosarcoma of the breast - specific findings of MRI. Breast Cancer; 2006;13(4):369-73
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  • [Title] Angiosarcoma of the breast - specific findings of MRI.
  • We present a case of low-grade angiosarcoma of the breast.
  • Core needle biopsy was performed, and a possible angiosarcoma was diagnosed.
  • It is not easy to diagnose the mammary angiosarcoma.
  • [MeSH-major] Breast Neoplasms / diagnosis. Hemangiosarcoma / diagnosis. Magnetic Resonance Imaging
  • [MeSH-minor] Adult. Contrast Media. Female. Humans. Mastectomy, Simple. Organometallic Compounds

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  • (PMID = 17146165.001).
  • [ISSN] 1340-6868
  • [Journal-full-title] Breast cancer (Tokyo, Japan)
  • [ISO-abbreviation] Breast Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Organometallic Compounds; 1BJ477IO2L / gadobutrol
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75. Truong PT, Jones SO, Martens B, Alexander C, Paquette M, Joe H, Hart J, Allan SJ: Treatment and outcomes in adult patients with primary cardiac sarcoma: the British Columbia Cancer Agency experience. Ann Surg Oncol; 2009 Dec;16(12):3358-65
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  • [Title] Treatment and outcomes in adult patients with primary cardiac sarcoma: the British Columbia Cancer Agency experience.
  • BACKGROUND: To evaluate treatment and survival in a cohort of patients referred to a Canadian institution with newly diagnosed primary cardiac sarcoma.
  • METHODS: Between 1990 and 2006, 16 patients were referred to the British Columbia Cancer Agency with pathologically confirmed sarcoma of cardiac origin.
  • The most common histologic subtype was angiosarcoma.
  • CONCLUSIONS: Patients with nonmetastatic cardiac sarcoma amenable to complete resection experienced improved survival.
  • [MeSH-major] Heart Neoplasms / therapy. Sarcoma / therapy
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Combined Modality Therapy. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Staging. Prognosis. Retrospective Studies. Survival Rate. Treatment Outcome

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  • (PMID = 19830494.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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76. Bai XF, Liang JW, Zhao DB, Shao YF, Zhao P: [Clinicopathologic features and treatment of primary splenic tumors]. Zhonghua Yi Xue Za Zhi; 2007 Jun 26;87(24):1673-5
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  • Of the 24 malignant cases, 16 suffered from splenic lymphoma and 8 from angiosarcoma.
  • The mean surviving time of angiosarcoma was only 10.4 months.
  • [MeSH-minor] Adult. Aged. Antigens, CD20 / analysis. Antigens, CD79 / analysis. Female. Follow-Up Studies. Humans. Immunohistochemistry. Male. Middle Aged. Retrospective Studies. Survival Analysis

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  • (PMID = 17825145.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, CD20; 0 / Antigens, CD79
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77. Solomon GJ, Kinkhabwala MM, Akhtar M: Inflammatory myofibroblastic tumor of the liver. Arch Pathol Lab Med; 2006 Oct;130(10):1548-51
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  • A left partial hepatectomy was performed; the preoperative differential diagnosis was for angiosarcoma and hepatocellular carcinoma.
  • [MeSH-minor] Actins / metabolism. Adult. Diagnosis, Differential. Hepatectomy. Hepatomegaly / etiology. Humans. Immunohistochemistry. Immunophenotyping. Inflammation / metabolism. Inflammation / pathology. Magnetic Resonance Imaging. Male. Muscle, Smooth / metabolism

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  • (PMID = 17090200.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins
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78. Yang XH, Wu QL, Yu XB, Xu CX, Ma BF, Zhang XM, Li SN, Lahn BT, Xiang AP: Nestin expression in different tumours and its relevance to malignant grade. J Clin Pathol; 2008 Apr;61(4):467-73
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  • RESULTS: Nestin was expressed predominantly in the cytoplasm of angiosarcoma, pancreatic adenocarcinoma and GIST samples, and some tumour cells expressed in the nucleus.
  • There was a statistically significant difference between the histoscore of nestin in high malignant GIST (2.2366 (0.6920)) and that in low malignant GIST (1.3783 (0.4268)) (p = 0.003); and also between that in high malignant angiosarcoma (1.9188 (0.2069)) and that in low malignant angiosarcoma (0.6474 (0.3273)) (p = 0.000).
  • CONCLUSIONS: Results suggest that the expression of nestin may play an important role in the development of some neoplasms such as GIST and angiosarcoma.
  • [MeSH-minor] Adenocarcinoma / metabolism. Adenocarcinoma / pathology. Adult. Aged. Female. Gastrointestinal Stromal Tumors / metabolism. Gastrointestinal Stromal Tumors / pathology. Hemangiosarcoma / metabolism. Hemangiosarcoma / pathology. Humans. Immunoenzyme Techniques. Male. Middle Aged. Nestin. Pancreatic Neoplasms / metabolism. Pancreatic Neoplasms / pathology

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  • (PMID = 17873113.001).
  • [ISSN] 1472-4146
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Intermediate Filament Proteins; 0 / NES protein, human; 0 / Neoplasm Proteins; 0 / Nerve Tissue Proteins; 0 / Nestin
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79. Nurkalem Z, Gorgulu S, Gumrukcu G, Eren M: Right atrial mass presenting as cardiac tamponade. Int J Cardiol; 2006 Sep 20;112(2):e20-2
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  • Intracavitary tumors such as angiosarcomas are prone to embolize, and occlude valves and vessels.
  • Histopathological findings were indicative of an angiosarcoma.
  • [MeSH-major] Cardiac Tamponade / etiology. Heart Atria. Heart Neoplasms / complications. Heart Neoplasms / diagnosis. Hemangiosarcoma / complications. Hemangiosarcoma / diagnosis
  • [MeSH-minor] Adult. Aorta / pathology. Echocardiography, Doppler, Pulsed. Female. Humans. Neoplasm Invasiveness

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  • (PMID = 16884795.001).
  • [ISSN] 1874-1754
  • [Journal-full-title] International journal of cardiology
  • [ISO-abbreviation] Int. J. Cardiol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Ireland
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80. Weaver J, Billings SD: Postradiation cutaneous vascular tumors of the breast: a review. Semin Diagn Pathol; 2009 Aug;26(3):141-9
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  • (1) postradiation cutaneous angiosarcoma, malignant vascular neoplasms with significant morbidity and mortality; and (2) atypical vascular lesions (AVL), vascular tumors that reportedly behave in a benign manner.
  • Although first described separately 15 years ago, the relationship between postradiation cutaneous angiosarcoma and AVL remains controversial.
  • It appears that, in at least some cases, angiosarcoma can arise in the context of AVL, suggesting that these lesions are part of a spectrum of the same disease process.
  • Herein, we will discuss the evolution of this topic while reviewing the various clinical, histopathologic, and prognostic characteristics of postradiation cutaneous angiosarcoma and AVL.
  • [MeSH-major] Breast Neoplasms / radiotherapy. Hemangiosarcoma / pathology. Neoplasms, Radiation-Induced / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Female. Humans. Middle Aged. Neoplasm Recurrence, Local. Prognosis

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  • (PMID = 20043513.001).
  • [ISSN] 0740-2570
  • [Journal-full-title] Seminars in diagnostic pathology
  • [ISO-abbreviation] Semin Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 21
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81. Burns CJ, Jammer BL, Bodnar CM: Mortality rates among chemical workers in the Kanawha Valley of West Virginia: 1940-1999. W V Med J; 2006 Jul-Aug;102(4):24-8
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  • We observed no new cases of angiosarcoma of the liver, a cause of death previously reported in association with vinyl chloride production at the South Charleston location.
  • [MeSH-minor] Adult. Aged. Carcinogens, Environmental / adverse effects. Cause of Death. Cohort Studies. Employment. Female. Follow-Up Studies. Healthy Worker Effect. Hemangiosarcoma / chemically induced. Hemangiosarcoma / mortality. Humans. Liver Neoplasms / chemically induced. Liver Neoplasms / mortality. Lymphoma, Large B-Cell, Diffuse / chemically induced. Lymphoma, Large B-Cell, Diffuse / mortality. Lymphoma, Non-Hodgkin / chemically induced. Lymphoma, Non-Hodgkin / mortality. Male. Middle Aged. Risk. Risk Factors. Sex Factors. Time Factors. Vinyl Chloride / adverse effects. West Virginia

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  • [CommentIn] W V Med J. 2006 Sep-Oct;102(5):5 [17285946.001]
  • (PMID = 17111678.001).
  • [ISSN] 0043-3284
  • [Journal-full-title] The West Virginia medical journal
  • [ISO-abbreviation] W V Med J
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Carcinogens, Environmental; WD06X94M2D / Vinyl Chloride
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82. Fleshman R, Mayerson J, Wakely PE Jr: Fine-needle aspiration biopsy of high-grade sarcoma: a report of 107 cases. Cancer; 2007 Dec 25;111(6):491-8
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  • [Title] Fine-needle aspiration biopsy of high-grade sarcoma: a report of 107 cases.
  • BACKGROUND: To the authors' knowledge, few studies exist demonstrating the reliability of fine-needle aspiration (FNA) biopsy for high-grade sarcoma (HGS).
  • Fifty-four cases were diagnosed as HGS, not otherwise specified, 8 as myxofibrosarcoma, 8 as osteosarcoma, 5 as malignant peripheral nerve sheath tumor, 5 as leiomyosarcoma, 4 as Ewing sarcoma, 4 as liposarcoma, 2 as epithelioid sarcoma, and 1 as angiosarcoma.
  • [MeSH-major] Biopsy, Fine-Needle. Cytodiagnosis. Sarcoma / diagnosis. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Antineoplastic Agents / therapeutic use. Bone Neoplasms / diagnosis. Female. Humans. Male. Middle Aged. Neoadjuvant Therapy. Predictive Value of Tests. Reproducibility of Results

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  • (PMID = 17941014.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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83. Chirife AM, Bello L, Celeste F, Giménez L, Gorostidy S: [Primary sarcomas of the breast]. Medicina (B Aires); 2006;66(2):135-8
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  • [Title] [Primary sarcomas of the breast].
  • [Transliterated title] Sarcomas primarios de mama.
  • Primary sarcomas of the breast are extremely rare with less than 1% of all malignant tumours of the breast reported in literature.
  • At our Institution 1315 malignant tumours of the breast were diagnosed between 1999-2004; nine of them corresponded to primary sarcomas: angiosarcoma (3), leiomyosarcoma (1), low-grade fibromyxoid sarcoma (1), dematofibrosarcoma protuberans (1), liposarcoma (1), osteosarcoma (1), malignant peripheral nerve sheath tumour (1).
  • [MeSH-major] Breast Neoplasms. Sarcoma
  • [MeSH-minor] Adult. Argentina / epidemiology. Biomarkers, Tumor / genetics. Biomarkers, Tumor / metabolism. Female. Humans. Incidence. Middle Aged. Phenotype. Prevalence. Prognosis. Retrospective Studies. Tumor Suppressor Protein p53 / genetics. Tumor Suppressor Protein p53 / metabolism


84. Radulescu D, Pripon S, Radulescu LI, Constantea NA, Gulei I: A rare case of primitive right atrium angio-sarcoma with favorable outcome, in a young female. Case report and literature review. Rev Med Chil; 2008 Oct;136(10):1311-6
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  • [Title] A rare case of primitive right atrium angio-sarcoma with favorable outcome, in a young female. Case report and literature review.
  • We report a 26 year-old female with a right atrium angiosarcoma with a surprisingly favorable outcome at 2 years follow-up after treatment with a combination of neoadjuvant chemotherapy and surgical resection.
  • The diagnosis of a malignant angiosarcoma was suggested afier computed tomography transthoracic and transesophageal echocardiography It was confirmed at surgery by a biopsy followed by histopathology and immunohistochemistry.
  • [MeSH-major] Heart Neoplasms / therapy. Hemangiosarcoma / therapy
  • [MeSH-minor] Adult. Biopsy. Combined Modality Therapy. Echocardiography, Transesophageal. Female. Heart Atria / ultrasonography. Humans. Pericardial Effusion / ultrasonography

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  • (PMID = 19194629.001).
  • [ISSN] 0034-9887
  • [Journal-full-title] Revista médica de Chile
  • [ISO-abbreviation] Rev Med Chil
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Chile
  • [Number-of-references] 26
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85. Ceyhan K, Percinel S, Kinkli G, Karaca E, Umudum H: Epithelioid angiosarcoma. Acta Cytol; 2010 Jan-Feb;54(1):109-12
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  • [Title] Epithelioid angiosarcoma.
  • [MeSH-major] Hemangiosarcoma / pathology. Liver Neoplasms / pathology
  • [MeSH-minor] Adult. Biopsy, Fine-Needle. Humans. Immunohistochemistry. Male

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  • (PMID = 20307003.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
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86. Sheu SY, Grabellus F, Schwertheim S, Mann K, Ensinger C, Ofner D, Bockhorn M, Fuhrer D, Schmid KW: COX-2 expression in highly aggressive thyroid malignancies - indication for a possible therapeutic option? Horm Metab Res; 2009 Apr;41(4):314-9
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  • Both anaplastic thyroid carcinoma (ATC) and angiosarcoma of the thyroid (AST) are highly aggressive malignancies with very limited therapeutic options.
  • [MeSH-major] Carcinoma / metabolism. Cyclooxygenase 2 / metabolism. Gene Expression. Hemangiosarcoma / metabolism. Thyroid Neoplasms / metabolism
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Retrospective Studies

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  • (PMID = 19048457.001).
  • [ISSN] 1439-4286
  • [Journal-full-title] Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme
  • [ISO-abbreviation] Horm. Metab. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] EC 1.14.99.1 / Cyclooxygenase 2; EC 1.14.99.1 / PTGS2 protein, human
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87. Bhutoria B, Konar A, Chakrabarti S, Das S: Retiform hemangioendothelioma with lymph node metastasis: a rare entity. Indian J Dermatol Venereol Leprol; 2009 Jan-Feb;75(1):60-2
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  • Retiform hemangioendothelioma (RH) is a rare, recently described, unique kind of low grade angiosarcoma.
  • Another such rare case of RH is being reported in an adult female who presented with a subcutaneous nodule, underwent multiple recurrences and uniquely metastasized to regional lymph node.
  • [MeSH-minor] Adult. Female. Humans. Lymphatic Metastasis

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  • (PMID = 19172034.001).
  • [ISSN] 0973-3922
  • [Journal-full-title] Indian journal of dermatology, venereology and leprology
  • [ISO-abbreviation] Indian J Dermatol Venereol Leprol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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88. Fehr M, Kuhn M, Mayer K, Padberg B, Ulmer U, Cathomas R: Metastatic angiosarcoma arising from the right atrium: unusual presentation and excellent response to treatment in a young patient. J Thorac Oncol; 2010 Aug;5(8):1301-2
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  • [Title] Metastatic angiosarcoma arising from the right atrium: unusual presentation and excellent response to treatment in a young patient.
  • [MeSH-major] Heart Atria / pathology. Hemangiosarcoma / pathology. Lung Neoplasms / secondary
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Humans. Male. Prognosis. Tomography, X-Ray Computed

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  • [CommentIn] J Thorac Oncol. 2011 May;6(5):970-1 [21623272.001]
  • (PMID = 20661090.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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89. Keeling IM, Ploner F, Rigler B: Familial cardiac angiosarcoma. Ann Thorac Surg; 2006 Oct;82(4):1576
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Familial cardiac angiosarcoma.
  • [MeSH-major] Cardiac Surgical Procedures. Heart Neoplasms / surgery. Hemangiosarcoma / surgery
  • [MeSH-minor] Adult. Antineoplastic Agents / therapeutic use. Fatal Outcome. Heart Transplantation. Humans. Male. Paclitaxel / therapeutic use

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  • [CommentOn] Ann Thorac Surg. 2005 May;79(5):1771-4 [15854980.001]
  • (PMID = 16996998.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Comment; Letter
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antineoplastic Agents; P88XT4IS4D / Paclitaxel
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90. Popovska S, Deliĭski T: [Rare case of florid vascular proliferation of small intestine complicated with intussusception and bowel obstruction]. Khirurgiia (Sofiia); 2005;(2):59-61
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  • We present a florid benign vascular proliferation of the jejunum in one adult patient, presented with intussusception.
  • In this cases, the proliferation was sufficiently exuberant to raise the possibility of angiosarcoma as a diagnostic consideration.

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  • (PMID = 18681150.001).
  • [ISSN] 0450-2167
  • [Journal-full-title] Khirurgii︠a︡
  • [ISO-abbreviation] Khirurgiia (Sofiia)
  • [Language] bul
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Bulgaria
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91. Husted TL, Neff G, Thomas MJ, Gross TG, Woodle ES, Buell JF: Liver transplantation for primary or metastatic sarcoma to the liver. Am J Transplant; 2006 Feb;6(2):392-7
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  • [Title] Liver transplantation for primary or metastatic sarcoma to the liver.
  • Sarcoma is generally a rare disease in the US, with poor survival in patients with both primary angiosarcoma and metastatic disease from sarcoma and GIST.
  • In order to determine if liver transplantation for sarcoma is a realistic option, we examined records of all patients in the US component of the Israel Penn International Transplant Tumor Registry were reviewed.
  • Those patients with liver failure from primary or metastatic liver sarcoma were evaluated.
  • 19 patients are identified having received liver transplantation after treatment for sarcoma of the liver, 6 patients with primary hepatic sarcoma and 13 patients with metastatic sarcoma of the liver.
  • Given the early recurrence of tumor and meager 1-year survival outcome, liver transplantation is a poor therapeutic choice for patients with either primary or metastatic liver sarcoma, including high-grade leiomyosarcoma (GIST) regardless of primary site or primary therapy.
  • [MeSH-major] Liver Neoplasms / surgery. Liver Transplantation. Sarcoma / surgery
  • [MeSH-minor] Adult. Aged. Disease-Free Survival. Female. Gastrointestinal Neoplasms / pathology. Humans. Male. Middle Aged. Survival Analysis. Tomography, X-Ray Computed. Treatment Outcome


92. Tucci E, Della Rocca C, Santilli F: Localized bacillary angiomatosis in the oral cavity: observations about a neoplasm with atypical behavior. Description of a case and review of the literature. Minerva Stomatol; 2006 Jan-Feb;55(1-2):67-75
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  • Bacillary angiomatosis can be clinically similar to the Kaposi's sarcoma and histologically confused with angiosarcoma, epitheloid hemangioma and pyogenic granuloma.
  • The high tendency to relapse, the capability in migration and to involve several localizations at the same time have induced the authors to deepen the research to exclude the possibility that it could be a Kaposi's sarcoma or a pyogenic granuloma and to get to an accurate diagnosis in order to resolve the disease.
  • [MeSH-minor] Adolescent. Adult. Ampicillin / analogs & derivatives. Ampicillin / therapeutic use. Bartonella henselae / pathogenicity. Bartonella quintana / pathogenicity. Child. Chlorhexidine / therapeutic use. Combined Modality Therapy. Diagnosis, Differential. Female. Gingival Neoplasms / diagnosis. Granuloma, Pyogenic / diagnosis. Hemangioendothelioma, Epithelioid / diagnosis. Hemangiosarcoma / diagnosis. Humans. Male. Pregnancy. Pregnancy Complications, Neoplastic / diagnosis. Recurrence. Sarcoma, Kaposi / diagnosis. Tooth Extraction

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  • (PMID = 16495874.001).
  • [ISSN] 0026-4970
  • [Journal-full-title] Minerva stomatologica
  • [ISO-abbreviation] Minerva Stomatol
  • [Language] eng; ita
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 7C782967RD / Ampicillin; 8GM2J22278 / bacampicillin; R4KO0DY52L / Chlorhexidine
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93. Kim JB, Kim SH, Lim SY, Roh SY, Cho GY, Song HJ, Park S, Lee J, Kim SJ: Primary angiosarcoma of the pulmonary trunk mimicking pulmonary thromboembolism. Echocardiography; 2010 Feb;27(2):E23-6
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  • [Title] Primary angiosarcoma of the pulmonary trunk mimicking pulmonary thromboembolism.
  • We present a case of primary angiosarcoma of the pulmonary trunk that was initially misdiagnosed as a subacute massive pulmonary thromboembolism in a 26-year-old woman.
  • This is an extremely rare disease that is usually indistinguishable from acute or chronic thromboembolic disease of the pulmonary arteries because the clinical and radiologic findings of pulmonary artery angiosarcoma are similar to those of pulmonary thromboembolism.
  • Although the incidence of pulmonary artery angiosarcoma is very low, our case demonstrates that this disease entity should be included in the differential diagnosis of pulmonary thromboembolism, especially in patients who do not respond to anticoagulant therapy or present with no identifiable source of thromboembolic events.
  • [MeSH-major] Hemangiosarcoma / ultrasonography. Pulmonary Artery / ultrasonography. Vascular Neoplasms / ultrasonography
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Pulmonary Embolism / ultrasonography

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  • (PMID = 20380673.001).
  • [ISSN] 1540-8175
  • [Journal-full-title] Echocardiography (Mount Kisco, N.Y.)
  • [ISO-abbreviation] Echocardiography
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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94. Chen TJ, Chiou CC, Chen CH, Kuo TT, Hong HS: Metastasis of mediastinal epithelioid angiosarcoma to the finger. Am J Clin Dermatol; 2008;9(3):181-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastasis of mediastinal epithelioid angiosarcoma to the finger.
  • Epithelioid angiosarcoma (EA) is a rare malignant, vascular tumor that is usually observed in middle-aged and elderly males.
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Fatal Outcome. Female. Humans

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  • (PMID = 18429648.001).
  • [ISSN] 1175-0561
  • [Journal-full-title] American journal of clinical dermatology
  • [ISO-abbreviation] Am J Clin Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] New Zealand
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95. Schmid H, Zietz C: Human herpesvirus 8 and angiosarcoma: analysis of 40 cases and review of the literature. Pathology; 2005 Aug;37(4):284-7
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  • [Title] Human herpesvirus 8 and angiosarcoma: analysis of 40 cases and review of the literature.
  • AIMS: To prove a possible involvement of the endotheliotropic human herpesvirus 8 (HHV-8) in the pathogenesis of angiosarcoma in samples from patients in a low HHV-8 seroprevalence area.
  • METHODS: A comprehensive series of angiosarcomas (n = 40) as well as positive and negative control tissues from patients with Kaposi's sarcoma, human immunodeficiency virus (HIV)-associated multicentric Castleman's disease or juvenile haemangioma, respectively, was analysed with two sensitive methods: immunohistochemical staining for the HHV-8 latency-associated nuclear antigen 1 (LANA-1); and polymerase chain reaction (PCR) for HHV-8 VP23 DNA sequences.
  • RESULTS: None of the angiosarcoma cases and none of the negative control samples (juvenile haemangiomas) revealed positive immunohistochemical staining with the LANA-1 antibody.
  • In contrast, HHV-8 LANA-1 was clearly detected in all analysed cases of Kaposi's sarcoma and multicentric Castleman's disease.
  • CONCLUSION: In conclusion, the great majority of angiosarcomas investigated to date, including the series of 40 angiosarcomas analysed here, does not contain HHV-8 DNA sequences or protein.
  • This argues against a relevant role of the endotheliotropic HHV-8 in the pathogenesis of angiosarcoma and, for vascular diseases, speaks in favour of a relatively restricted pathogenic role of HHV-8 to Kaposi's sarcoma and multicentric Castleman's disease.
  • [MeSH-major] Hemangiosarcoma / virology. Herpesviridae Infections / epidemiology. Herpesvirus 8, Human / isolation & purification. Tumor Virus Infections / epidemiology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Animals. Female. Giant Lymph Node Hyperplasia / virology. Humans. Immunohistochemistry. Male. Middle Aged. Oncogenic Viruses / isolation & purification. Polymerase Chain Reaction. Sarcoma, Kaposi / virology

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  • (PMID = 16194826.001).
  • [ISSN] 0031-3025
  • [Journal-full-title] Pathology
  • [ISO-abbreviation] Pathology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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96. Sanchez-Mejia RO, Ojemann SG, Simko J, Chaudhary UB, Levy J, Lawton MT: Sacral epithelioid angiosarcoma associated with a bleeding diathesis and spinal epidural hematoma: case report. J Neurosurg Spine; 2006 Mar;4(3):246-50
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  • [Title] Sacral epithelioid angiosarcoma associated with a bleeding diathesis and spinal epidural hematoma: case report.
  • Epithelioid angiosarcoma of bone is a rare, high-grade lesion that is highly vascular and can be associated with a bleeding diathesis.
  • An association has been reported in angiosarcomas in other locations with coagulopathy from tumor-related disseminated intravascular coagulopathy and fibrinolysis.
  • The authors report the case of a rare occurrence of a primary sacral epithelioid angiosarcoma associated with a large epidural hematoma and a severe bleeding diathesis.
  • This case represents the first report of a primary epithelioid angiosarcoma in the sacrum and emphasizes that the coagulopathy seen in angiosarcoma is also a feature of this epithelioid variant.
  • [MeSH-major] Bone Neoplasms / complications. Hemangiosarcoma / complications
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Blood Transfusion. Combined Modality Therapy. Doxorubicin / administration & dosage. Embolization, Therapeutic. Female. Hematoma, Epidural, Spinal. Hemorrhagic Disorders. Hemostasis. Humans. Ifosfamide / administration & dosage. Laminectomy. Magnetic Resonance Imaging. Sacrum / pathology. Sacrum / surgery. Treatment Outcome

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  • (PMID = 16572625.001).
  • [ISSN] 1547-5654
  • [Journal-full-title] Journal of neurosurgery. Spine
  • [ISO-abbreviation] J Neurosurg Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 80168379AG / Doxorubicin; UM20QQM95Y / Ifosfamide
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97. Berry MF, Williams M, Welsby I, Lin S: Cardiac angiosarcoma presenting with right coronary artery pseudoaneurysm. J Cardiothorac Vasc Anesth; 2010 Aug;24(4):633-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cardiac angiosarcoma presenting with right coronary artery pseudoaneurysm.
  • [MeSH-major] Aneurysm, False / diagnosis. Coronary Vessels / pathology. Heart Neoplasms / diagnosis. Hemangiosarcoma / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Male

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  • (PMID = 19525126.001).
  • [ISSN] 1532-8422
  • [Journal-full-title] Journal of cardiothoracic and vascular anesthesia
  • [ISO-abbreviation] J. Cardiothorac. Vasc. Anesth.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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98. Hui C: An unusual cause of diffuse pulmonary haemorrhage. Clin Respir J; 2008 Jul;2(3):183-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Tumours, including angiosarcoma lung metastases, are an unusual cause of pulmonary haemorrhage.
  • The patient died within 3 months after initial presentation and an autopsy revealed a chest wall angiosarcoma with pulmonary and cerebellar metastases.
  • CONCLUSION: Pulmonary angiosarcoma metastases should be included in the differential diagnosis of diffuse pulmonary haemorrhage, especially in a young, previously healthy patient with normal renal function, particularly as the pathological diagnosis may be difficult and even misleading.
  • [MeSH-major] Hemangiosarcoma / pathology. Hemorrhage / diagnosis. Lung Diseases / diagnosis. Lung Neoplasms / pathology
  • [MeSH-minor] Adult. Autopsy. Cerebral Hemorrhage / diagnosis. Cerebral Hemorrhage / etiology. Disease Progression. Fatal Outcome. Hemoptysis / diagnosis. Hemoptysis / etiology. Hemothorax / diagnosis. Hemothorax / etiology. Humans. Male. Radiography, Thoracic. Risk Assessment. Severity of Illness Index. Tomography, X-Ray Computed

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  • (PMID = 20298327.001).
  • [ISSN] 1752-699X
  • [Journal-full-title] The clinical respiratory journal
  • [ISO-abbreviation] Clin Respir J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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99. Mekinian A, Lambert M, Queyrel V, Launay D, Morell-Dubois S, Hachulla E, Mathurin P, Hatron PY: [Adult-onset Still's disease and hepatic angiosarcoma, a fortuitous association or a paraneoplastic syndrome: a case-report]. Rev Med Interne; 2008 Nov;29(11):936-9
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  • [Title] [Adult-onset Still's disease and hepatic angiosarcoma, a fortuitous association or a paraneoplastic syndrome: a case-report].
  • Adult-onset Still's disease is a systemic disorder without specific histological feature.
  • Nevertheless, patients with paraneoplastic adult-onset Still's disease have been reported.
  • We report a patient with an adult-onset Still's disease who presented with a liver involvement at onset.
  • Two years later, a liver angiosarcoma was diagnosed.
  • This report underlines the difficulty of the diagnosis of the adult-onset Still's disease even in the presence of Yamaguchi et al.
  • 's [Medicine 81 (2002) 194-200] classification criteria and may suggest a link between the initial clinical picture and the discovery nearly two years later, of a liver angiosarcoma.

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  • (PMID = 18572281.001).
  • [ISSN] 0248-8663
  • [Journal-full-title] La Revue de medecine interne
  • [ISO-abbreviation] Rev Med Interne
  • [Language] FRE
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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100. Stoian I, Piser IT, Kulcsar I, Chioncel O, Carp A, Macarie C: Rare tumors of the heart--angiosarcoma, pericardial lipoma, leiomyosarcoma. Three case reports. J Med Life; 2010 Apr-Jun;3(2):178-82
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rare tumors of the heart--angiosarcoma, pericardial lipoma, leiomyosarcoma. Three case reports.
  • Three cases of surgically/biopsy proven angiosarcoma of the right atrium, pericardial lipoma and leiomyosarcoma of inferior vena cava--demonstrated by ultrasound, computed tomography (CT) and magnetic resonance imaging (MRI)--are presented here.
  • [MeSH-major] Heart Neoplasms / diagnosis. Hemangiosarcoma / diagnosis. Leiomyosarcoma / diagnosis. Lipoma / diagnosis
  • [MeSH-minor] Adult. Echocardiography. Female. Heart Atria. Humans. Magnetic Resonance Imaging. Middle Aged. Pericardium. Tomography, X-Ray Computed. Vena Cava, Inferior

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  • [Cites] Surg Today. 2004;34(4):370-3 [15052457.001]
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  • (PMID = 20968205.001).
  • [ISSN] 1844-122X
  • [Journal-full-title] Journal of medicine and life
  • [ISO-abbreviation] J Med Life
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Romania
  • [Other-IDs] NLM/ PMC3019051
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