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1. Wei J, Zhou XF, Zhao F, Zhou JF, Chen Y: Immunologic characteristics and prognosis of myelodysplastic syndrome new subtype: refractory anemia with excess blasts-II. Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2009 Feb;17(1):111-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • 35 cases of adult patients with de novo MDS were investigated.
  • 47 cases of acute myeloid leukemia (AML) M1, 51 cases of AML-M(2) and 38 cases of acute lymphocytic leukemia (ALL) were selected as control.
  • It is concluded that RAEB-II expresses mainly myeloid antigen without or with little expression of lymphoid antigen.


2. Fu JF, Liang DC, Shih LY: Analysis of acute leukemias with MLL/ENL fusion transcripts: identification of two novel breakpoints in ENL. Am J Clin Pathol; 2007 Jan;127(1):24-30
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  • [Title] Analysis of acute leukemias with MLL/ENL fusion transcripts: identification of two novel breakpoints in ENL.
  • t(11;19)(q23;p13.3); is one of the common chromosomal translocations in acute leukemias involving MLL rearrangements.
  • In a study of acute leukemias, 148 patients were identified to have MLL rearrangements by Southern blot analysis.
  • Of 15 patients with MLL/ENL, 7 had precursor B-cell acute lymphoblastic leukemia, 4 had T-cell acute lymphoblastic leukemia, and 4 had acute myeloid leukemia.
  • [MeSH-major] Leukemia, Myeloid / genetics. Myeloid-Lymphoid Leukemia Protein / genetics. Neoplasm Proteins / genetics. Nuclear Proteins / genetics. Oncogene Fusion / genetics. Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics. Transcription Factors / genetics. Translocation, Genetic / genetics
  • [MeSH-minor] Acute Disease. Adolescent. Adult. Aged. Child. Child, Preschool. Chromosomes, Human, Pair 11 / genetics. Chromosomes, Human, Pair 19 / genetics. Female. Gene Rearrangement. Histone-Lysine N-Methyltransferase. Humans. Infant. Infant, Newborn. Male. Reverse Transcriptase Polymerase Chain Reaction. Treatment Outcome

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  • (PMID = 17145626.001).
  • [ISSN] 0002-9173
  • [Journal-full-title] American journal of clinical pathology
  • [ISO-abbreviation] Am. J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / MLL protein, human; 0 / MLLT1 protein, human; 0 / Neoplasm Proteins; 0 / Nuclear Proteins; 0 / Transcription Factors; 149025-06-9 / Myeloid-Lymphoid Leukemia Protein; EC 2.1.1.43 / Histone-Lysine N-Methyltransferase
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3. Mantadakis E, Pontikoglou C, Papadaki HA, Aggelidakis G, Samonis G: Fatal Fournier's gangrene in a young adult with acute lymphoblastic leukemia. Pediatr Blood Cancer; 2007 Nov;49(6):862-4
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  • [Title] Fatal Fournier's gangrene in a young adult with acute lymphoblastic leukemia.
  • We describe a case of fatal FG in a 21-year-old man with acute lymphoblastic leukemia who was receiving remission-induction chemotherapy.
  • [MeSH-major] Drug Resistance, Multiple, Bacterial. Fournier Gangrene / etiology. Pancytopenia / complications. Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications. Pseudomonas Infections / etiology
  • [MeSH-minor] Adult. Anti-Bacterial Agents / administration & dosage. Fatal Outcome. Humans. Male. Pseudomonas aeruginosa. Scrotum / pathology. Scrotum / surgery

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  • [Copyright] (c) 2006 Wiley-Liss, Inc.
  • (PMID = 16425246.001).
  • [ISSN] 1545-5009
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents
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4. Busse A, Gökbuget N, Siehl JM, Hoelzer D, Schwartz S, Rietz A, Thiel E, Keilholz U: Wilms' tumor gene 1 (WT1) expression in subtypes of acute lymphoblastic leukemia (ALL) of adults and impact on clinical outcome. Ann Hematol; 2009 Dec;88(12):1199-205
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  • [Title] Wilms' tumor gene 1 (WT1) expression in subtypes of acute lymphoblastic leukemia (ALL) of adults and impact on clinical outcome.
  • Wilms' tumor gene 1 (WT1) is gaining increasing attention as a therapeutic target molecule due to its common expression in acute leukemias and its involvement in cell proliferation.
  • Here, we reported on WT1 messenger RNA expression levels at diagnosis in a series of 238 adult acute lymphoblastic leukemia (ALL) samples of various subtypes and clinical outcome.
  • Compared to a cohort of acute myeloid leukemia patients, the median WT1 expression level in ALL was significantly lower with large variations among different ALL subgroups.
  • Specifically, WT1 expression levels were low in mature B-ALL and highest in ALL cases with co-expression of myeloid markers, making it a useful therapeutic target molecule in adult ALL with the exception of mature B-ALL.
  • [MeSH-major] Gene Expression Regulation, Leukemic. Genes, Wilms Tumor. Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics. Precursor Cell Lymphoblastic Leukemia-Lymphoma / physiopathology. WT1 Proteins
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biomarkers / blood. Female. Humans. Immunophenotyping. Kaplan-Meier Estimate. Male. Middle Aged. Multicenter Studies as Topic. Prognosis. RNA, Messenger / genetics. RNA, Messenger / metabolism. Treatment Outcome. Young Adult

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  • (PMID = 19404640.001).
  • [ISSN] 1432-0584
  • [Journal-full-title] Annals of hematology
  • [ISO-abbreviation] Ann. Hematol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers; 0 / RNA, Messenger; 0 / WT1 Proteins
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5. Sakr Y, Lobo S, Knuepfer S, Esser E, Bauer M, Settmacher U, Barz D, Reinhart K: Anemia and blood transfusion in a surgical intensive care unit. Crit Care; 2010;14(3):R92
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  • METHODS: We retrospectively analyzed the prospectively collected data from all adult patients (>18 years old) admitted to a 50-bed surgical ICU between 1st March 2004 and 30th July 2006.
  • Lower hemoglobin concentrations were associated with a higher Simplified Acute Physiology Score II and Sequential Organ Failure Assessment score, greater mortality rates, and longer ICU and hospital lengths of stay.

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  • (PMID = 20497535.001).
  • [ISSN] 1466-609X
  • [Journal-full-title] Critical care (London, England)
  • [ISO-abbreviation] Crit Care
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Hemoglobins
  • [Other-IDs] NLM/ PMC2911729
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6. Berriche O, Amrouche C, Jamoussi H, Blouza S: Efficacy and safety of statins in the treatment of diabetic dyslipidemia. Tunis Med; 2010 Feb;88(2):80-4
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  • BACKGROUND: The Adult Treatment Panel III recommends 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors or statins as first-line-lipid-altering therapy for all adult patients with diabetes mellitus.

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  • (PMID = 20415163.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Tunisia
  • [Chemical-registry-number] 0 / Hydroxymethylglutaryl-CoA Reductase Inhibitors; 97C5T2UQ7J / Cholesterol
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7. Alger-Mayer S, Polimeni JM, Malone M: Preoperative weight loss as a predictor of long-term success following Roux-en-Y gastric bypass. Obes Surg; 2008 Jul;18(7):772-5
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  • All adult patients with 3- and 4-year follow-up data since the start of the study in 1998 to September 2007 were included.
  • [MeSH-minor] Adult. Body Mass Index. Female. Follow-Up Studies. Health Knowledge, Attitudes, Practice. Humans. Male. Middle Aged. Predictive Value of Tests. Prospective Studies. Time Factors. Treatment Outcome

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  • (PMID = 18392899.001).
  • [ISSN] 0960-8923
  • [Journal-full-title] Obesity surgery
  • [ISO-abbreviation] Obes Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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8. Cheng B, Xie G, Yao S, Wu X, Guo Q, Gu M, Fang Q, Xu Q, Wang D, Jin Y, Yuan S, Wang J, Du Z, Sun Y, Fang X: Epidemiology of severe sepsis in critically ill surgical patients in ten university hospitals in China. Crit Care Med; 2007 Nov;35(11):2538-46
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PATIENTS: All adult admissions in studied intensive care units from December 1, 2004, to November 30, 2005.
  • Risk factors for hospital mortality included age, chronic comorbidity of malignant neoplasm, Gram-positive bacterial infection, invasive fungal infection, admission Acute Physiology Score, and admission Sequential Organ Failure Assessment score of respiratory dysfunction and cardiovascular dysfunction.
  • [MeSH-minor] Adult. Aged. China. Critical Illness. Female. Hospitals, University. Humans. Intensive Care Units. Male. Middle Aged. Prospective Studies. Severity of Illness Index


9. Kumar P, Defor TE, Brunstein C, Barker JN, Wagner JE, Weisdorf DJ, Burns LJ: Allogeneic hematopoietic stem cell transplantation in adult acute lymphocytic leukemia: impact of donor source on survival. Biol Blood Marrow Transplant; 2008 Dec;14(12):1394-400
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  • [Title] Allogeneic hematopoietic stem cell transplantation in adult acute lymphocytic leukemia: impact of donor source on survival.
  • We studied the relative impact of donor source on outcomes following myeloablative hematopoietic stem cell transplantation (HSCT) for adult patients with acute lymphocytic leukemia (ALL).
  • Similarly leukemia free survival (LFS) at 3 years was better in the UCB group at 61% (95% CI 38%-84%) than 27% (95% CI 18%-36%) in the MRD and only 13% (95% CI 0%-31%) in the URD:M group and 14% (95%CI 0%-33%) in URD:MM group.
  • [MeSH-major] Donor Selection. HLA Antigens. Hematopoietic Stem Cell Transplantation. Living Donors. Precursor Cell Lymphoblastic Leukemia-Lymphoma / mortality
  • [MeSH-minor] Adolescent. Adult. Disease-Free Survival. Female. Humans. Male. Middle Aged. Recurrence. Retrospective Studies. Risk Factors. Survival Rate. Transplantation, Homologous

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  • (PMID = 19041062.001).
  • [ISSN] 1523-6536
  • [Journal-full-title] Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
  • [ISO-abbreviation] Biol. Blood Marrow Transplant.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA008748
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / HLA Antigens
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10. Roche-Lestienne C, Deluche L, Corm S, Tigaud I, Joha S, Philippe N, Geffroy S, Laï JL, Nicolini FE, Preudhomme C, Fi-LMC group: RUNX1 DNA-binding mutations and RUNX1-PRDM16 cryptic fusions in BCR-ABL+ leukemias are frequently associated with secondary trisomy 21 and may contribute to clonal evolution and imatinib resistance. Blood; 2008 Apr 1;111(7):3735-41
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Acquired molecular abnormalities (mutations or chromosomal translocations) of the RUNX1 transcription factor gene are frequent in acute myeloblastic leukemias (AMLs) and in therapy-related myelodysplastic syndromes, but rarely in acute lymphoblastic leukemias (ALLs) and chronic myelogenous leukemias (CMLs).
  • We did not found any mutation in de novo BCR-ABL+ ALLs or lymphoid BC CML.
  • [MeSH-major] Antineoplastic Agents / administration & dosage. Blast Crisis / genetics. Core Binding Factor Alpha 2 Subunit / genetics. DNA-Binding Proteins / genetics. Drug Resistance, Neoplasm / genetics. Fusion Proteins, bcr-abl / genetics. Leukemia / genetics. Piperazines / administration & dosage. Pyrimidines / administration & dosage. Transcription Factors / genetics. Trisomy / genetics
  • [MeSH-minor] Acute Disease. Adult. Aged. Aged, 80 and over. Benzamides. Chromosomes, Human. Chronic Disease. Disease-Free Survival. Female. Humans. Imatinib Mesylate. Male. Middle Aged. Myelodysplastic Syndromes / chemically induced. Myelodysplastic Syndromes / genetics. Myelodysplastic Syndromes / metabolism. Myelodysplastic Syndromes / mortality. Phenotype. Point Mutation. Retrospective Studies. Survival Rate. Translocation, Genetic / drug effects. Translocation, Genetic / genetics

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  • (PMID = 18202228.001).
  • [ISSN] 0006-4971
  • [Journal-full-title] Blood
  • [ISO-abbreviation] Blood
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Benzamides; 0 / Core Binding Factor Alpha 2 Subunit; 0 / DNA-Binding Proteins; 0 / PRDM16 protein, human; 0 / Piperazines; 0 / Pyrimidines; 0 / RUNX1 protein, human; 0 / Transcription Factors; 8A1O1M485B / Imatinib Mesylate; EC 2.7.10.2 / Fusion Proteins, bcr-abl
  • [General-notes] NLM/ Investigator list not found.
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11. Ansari M, Krajinovic M: Pharmacogenomics of acute leukemia. Pharmacogenomics; 2007 Jul;8(7):817-34
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pharmacogenomics of acute leukemia.
  • Leukemia exists in two different forms, myeloid and lymphoid.
  • Acute lymphoblastic leukemia more frequently occurs in children, whereas the risk of acute myeloid leukemia is more common in adults.
  • Prognosis is particularly poor in adult acute myeloid leukemia.
  • Treatment failure in childhood acute lymphoblastic leukemia due to drug resistance remains the leading cause of cancer-related death in children.
  • Here, we provide an overview of pharmacogenetics studies carried out in children and adults with acute lymphoblastic leukemia and acute myeloid leukemia, attempting to find the associations between treatment responses and polymorphisms in the genes whose products are needed for metabolism, and effects of drugs used in the treatment of leukemia.
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Leukemia, Myeloid, Acute / drug therapy. Leukemia, Myeloid, Acute / genetics. Pharmacogenetics
  • [MeSH-minor] Child. Humans. Polymorphism, Genetic. Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy. Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics

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  • (PMID = 18240908.001).
  • [ISSN] 1744-8042
  • [Journal-full-title] Pharmacogenomics
  • [ISO-abbreviation] Pharmacogenomics
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  • [Number-of-references] 130
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12. Jeng A, Beheshti M, Li J, Nathan R: The role of beta-hemolytic streptococci in causing diffuse, nonculturable cellulitis: a prospective investigation. Medicine (Baltimore); 2010 Jul;89(4):217-26
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  • To investigate this issue, we conducted a prospective investigation between December 2004 and June 2007, enrolling all adult patients admitted to the inpatient service at the Olive View-UCLA Medical Center, a county hospital of Los Angeles, with diffuse, nonculturable cellulitis.
  • Acute and convalescent serologies for anti-streptolysin-O and anti-DNase-B antibodies were obtained.
  • [MeSH-minor] Adipose Tissue. Adolescent. Adult. Aged. Aged, 80 and over. Antistreptolysin / blood. Bacterial Proteins / immunology. Deoxyribonucleases / immunology. Drug Resistance, Multiple, Bacterial. Female. Humans. Male. Methicillin-Resistant Staphylococcus aureus. Middle Aged. Prospective Studies. Streptolysins / immunology. Young Adult. beta-Lactams / therapeutic use

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  • (PMID = 20616661.001).
  • [ISSN] 1536-5964
  • [Journal-full-title] Medicine
  • [ISO-abbreviation] Medicine (Baltimore)
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Bacterial; 0 / Bacterial Proteins; 0 / Streptolysins; 0 / beta-Lactams; 0 / streptolysin O; 9006-92-2 / Antistreptolysin; EC 3.1.- / Deoxyribonucleases; EC 3.1.4.- / deoxyribonuclease B
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13. Murakami AM, Anderson SW, Soto JA, Kertesz JL, Ozonoff A, Rhea JT: Active extravasation of the abdomen and pelvis in trauma using 64MDCT. Emerg Radiol; 2009 Sep;16(5):375-82
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  • All adult patients scanned with 64MDCT who sustained blunt or penetrating abdomino-pelvic trauma and had findings of active extravasation at our Level I trauma center during a 30-month period were included.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Ultrasonography

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  • (PMID = 19271251.001).
  • [ISSN] 1438-1435
  • [Journal-full-title] Emergency radiology
  • [ISO-abbreviation] Emerg Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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14. Vandijck DM, Blot SI, Decruyenaere JM, Vanholder RC, De Waele JJ, Lameire NH, Claus S, De Schuijmer J, Dhondt AW, Verschraegen G, Hoste EA: Costs and length of stay associated with antimicrobial resistance in acute kidney injury patients with bloodstream infection. Acta Clin Belg; 2008 Jan-Feb;63(1):31-8
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  • [Title] Costs and length of stay associated with antimicrobial resistance in acute kidney injury patients with bloodstream infection.
  • Intensive care unit (ICU) patients, and particularly those with acute kidney injury (AKI), are at high risk for developing nosocomial bloodstream infections (BSI) due to multi-drug-resistant strains.
  • METHODS: Historical study (1995-2004) enrolling all adult RRT-dependent ICU patients with AKI and nosocomial BSI.
  • [MeSH-major] Acute Kidney Injury / economics. Bacteremia / economics. Drug Resistance, Bacterial. Health Care Costs. Length of Stay

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  • (PMID = 18386763.001).
  • [ISSN] 1784-3286
  • [Journal-full-title] Acta clinica Belgica
  • [ISO-abbreviation] Acta Clin Belg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Belgium
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15. Winston FK, Kallan MJ, Senserrick TM, Elliott MR: Risk factors for death among older child and teenaged motor vehicle passengers. Arch Pediatr Adolesc Med; 2008 Mar;162(3):253-60
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  • Just more than three-quarters as many passengers (aged 8-17 years) were in crashes with 16- to 19-year-old drivers as with all adult drivers (those aged > or =25 years), with double the passenger fatality rate.

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  • [CommentIn] Arch Pediatr Adolesc Med. 2008 Sep;162(9):898; author reply 898 [18762612.001]
  • (PMID = 18316663.001).
  • [ISSN] 1538-3628
  • [Journal-full-title] Archives of pediatrics & adolescent medicine
  • [ISO-abbreviation] Arch Pediatr Adolesc Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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16. Eckstein M, Stratton SJ, Chan LS: Termination of resuscitative efforts for out-of-hospital cardiac arrests. Acad Emerg Med; 2005 Jan;12(1):65-70
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  • METHODS: This was an observational one-year study that included all adult patients in the city of Los Angeles with nontraumatic, out-of-hospital cardiac arrests with attempted resuscitative efforts by paramedics.
  • [MeSH-minor] Adult. Aged. Analysis of Variance. California. Cohort Studies. Female. Humans. Logistic Models. Male. Middle Aged. Probability. Risk Assessment. Survival Analysis. Telecommunications. Urban Population

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  • (PMID = 15635140.001).
  • [ISSN] 1069-6563
  • [Journal-full-title] Academic emergency medicine : official journal of the Society for Academic Emergency Medicine
  • [ISO-abbreviation] Acad Emerg Med
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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17. Kobayashi S, Obata M, Hagihara M, Motohashi K, Ito S, Ohshima R, Sakai R, Maruta A, Kanamori H: The presence of mature granulocytes/monocytes derived from leukemic cells in MLL-associated leukemia. Int J Hematol; 2009 Dec;90(5):591-6
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  • [Title] The presence of mature granulocytes/monocytes derived from leukemic cells in MLL-associated leukemia.
  • We observed the mature granulocytes/monocytes derived from leukemic cells in patients with acute myeloid leukemia who present mixed lineage leukemia gene (MLL).
  • These findings suggest that subgroup of leukemia cells with MLL rearrangement has the differentiation potential of leukemic cells and mature granulocytes/monocytes derived from MLL clones may be biologically different from normal mature cells.
  • [MeSH-major] Leukemia, Myeloid, Acute / genetics. Leukemia, Myeloid, Acute / pathology. Myeloid-Lymphoid Leukemia Protein / genetics
  • [MeSH-minor] Adult. Bone Marrow Cells / pathology. Female. Granulocytes / pathology. Humans. Male. Middle Aged. Monocytes / pathology

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  • [ISSN] 1865-3774
  • [Journal-full-title] International journal of hematology
  • [ISO-abbreviation] Int. J. Hematol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 149025-06-9 / Myeloid-Lymphoid Leukemia Protein
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18. Gekas C, Rhodes KE, Gereige LM, Helgadottir H, Ferrari R, Kurdistani SK, Montecino-Rodriguez E, Bassel-Duby R, Olson E, Krivtsov AV, Armstrong S, Orkin SH, Pellegrini M, Mikkola HK: Mef2C is a lineage-restricted target of Scl/Tal1 and regulates megakaryopoiesis and B-cell homeostasis. Blood; 2009 Apr 9;113(15):3461-71
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  • The basic helix-loop-helix transcription factor stem cell leukemia gene (Scl) is a master regulator for hematopoiesis essential for hematopoietic specification and proper differentiation of the erythroid and megakaryocyte lineages.
  • However, adult VavCre(+)Mef2C(fl/fl) mice exhibited platelet defects similar to those observed in Scl-deficient mice.
  • In addition, an Scl-independent requirement for Mef2C in B-lymphoid homeostasis was observed in Mef2C-deficient mice, characterized as severe age-dependent reduction of specific B-cell progenitor populations reminiscent of premature aging.
  • In summary, this work identifies Mef2C as an integral member of hematopoietic transcription factors with distinct upstream regulatory mechanisms and functional requirements in megakaryocyte and B-lymphoid lineages.

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  • (PMID = 19211936.001).
  • [ISSN] 1528-0020
  • [Journal-full-title] Blood
  • [ISO-abbreviation] Blood
  • [Language] ENG
  • [Grant] United States / NIGMS NIH HHS / GM / T32 GM007185; United States / NIGMS NIH HHS / GM / GM07185
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Basic Helix-Loop-Helix Transcription Factors; 0 / MEF2 Transcription Factors; 0 / Mef2c protein, mouse; 0 / Myogenic Regulatory Factors; 0 / Proto-Oncogene Proteins; 0 / Tal1 protein, mouse
  • [Other-IDs] NLM/ PMC2945827
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19. Takita J, Motomura A, Koh K, Ida K, Taki T, Hayashi Y, Igarashi T: Acute megakaryoblastic leukemia in a child with the MLL-AF4 fusion gene. Eur J Haematol; 2009 Aug;83(2):149-53
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  • [Title] Acute megakaryoblastic leukemia in a child with the MLL-AF4 fusion gene.
  • Mixed-lineage leukemia (MLL) rearrangements are commonly observed in childhood acute lymphoblastic and myeloid leukemia, as well as therapy-related leukemia.
  • However, the occurrence of MLL rearrangements in acute megakaryoblastic leukemia (AMKL) is very rare.
  • MLL-AF4 is derived from t(4;11)(q21:q23) and occurs exclusively in B-cell lineage leukemia.
  • To our knowledge, MLL-AF4 as well as t(4;11)(q21:q23) has not been reported in adult and childhood AMKL.
  • Thus, our case provides new insight into the molecular mechanisms of MLL-AF4-associated leukemia.
  • [MeSH-major] Leukemia, Megakaryoblastic, Acute / genetics. Myeloid-Lymphoid Leukemia Protein / genetics. Oncogene Proteins, Fusion / genetics

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  • (PMID = 19459927.001).
  • [ISSN] 1600-0609
  • [Journal-full-title] European journal of haematology
  • [ISO-abbreviation] Eur. J. Haematol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / MLL-AF4 fusion protein, human; 0 / Oncogene Proteins, Fusion; 149025-06-9 / Myeloid-Lymphoid Leukemia Protein
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20. Karbasian-Esfahani M, Wiernik PH, Yeddu M, Abebe L: Leukemic infiltration of the breast in acute lymphocytic leukemia (ALL). Hematology; 2008 Apr;13(2):101-6
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  • [Title] Leukemic infiltration of the breast in acute lymphocytic leukemia (ALL).
  • Extramedullary leukemic infiltration of the breast in adult acute lymphocytic leukemia (ALL) is rare.
  • [MeSH-major] Breast Neoplasms / secondary. Leukemic Infiltration. Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology
  • [MeSH-minor] Adult. Bone Marrow Examination. Breast / pathology. Female. Humans. Treatment Outcome

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  • (PMID = 18616877.001).
  • [ISSN] 1607-8454
  • [Journal-full-title] Hematology (Amsterdam, Netherlands)
  • [ISO-abbreviation] Hematology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 35
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21. Zhao J, Yin YM, Zhao YL, Sun Y, Wang JB, Zhong J, Zhang X, Fei XH, Shan FX, Liu HX, Wang T, Wang H, Tong CR, Wu T, Lu DP: [Clinical and molecular biologic characteristics of 36 cases of leukemia with 11q23/mll]. Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2010 Dec;18(6):1381-5
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  • [Title] [Clinical and molecular biologic characteristics of 36 cases of leukemia with 11q23/mll].
  • This study was aimed to analyze the clinical and cytogenetic characteristics of acute leukemia with 11q23/mll rearrangement and explore the reasonable therapeutic principles.
  • Characteristics in general situation, morphology, immunology, molecular biology, cytogenetics, treatment and overall survival of 36 cases of acute leukemias with mll gene rearrangement were studied and analyzed.
  • The results showed that 36 cases with mll gene rearrangement were found positive (7.2%) in 494 patients with acute leukemia.
  • Among the 36 cases of mll rearrangement positive, 32 cases were diagnosed as acute myeloid leukemia (AML) with myeloid antigen expression, of which 5 cases expressed lymphoblastic differentiation antigen; 4 cases were classified as B-lineage acute lymphoblastic leukemia (ALL), of which non-lineage myeloid expression pattern were found in 3 cases.
  • It is concluded that acute leukemia patients with mll gene rearrangement show poor response to chemotherapy, high recurrence rate and poor prognosis.

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  • (PMID = 21176334.001).
  • [ISSN] 1009-2137
  • [Journal-full-title] Zhongguo shi yan xue ye xue za zhi
  • [ISO-abbreviation] Zhongguo Shi Yan Xue Ye Xue Za Zhi
  • [Language] CHI
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / MLL protein, human; 149025-06-9 / Myeloid-Lymphoid Leukemia Protein; EC 2.1.1.43 / Histone-Lysine N-Methyltransferase
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22. Jiménez LM, Duque FL, Baer PN, Jiménez SB: Necrotizing ulcerative periodontal diseases in children and young adults in Medellín, Colombia, 1965--2000. J Int Acad Periodontol; 2005 Apr;7(2):55-63
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  • Previous findings that necrotizing ulcerative gingivitis (NUG) is a precursor to noma or cancrum oris were confirmed by the follow-up of these clinical conditions in a study of 45 Colombian patients: necrotizing ulcerative gingivitis (NUG, n = 29), necrotizing ulcerative periodontitis (NUP, n = 7) and noma (n = 9).
  • Almost all the patients came from low socioeconomic groups and presented with predisposing and/or contributing factors, such as acute herpetic gingivostomatitis, measles, and leukemia (including acute lymphoblastic and chronic lymphoid leukemia).
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Colombia. Female. Gingiva / pathology. Humans. Leukemia / complications. Male. Malnutrition / complications. Measles / complications

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  • (PMID = 15912925.001).
  • [ISSN] 1466-2094
  • [Journal-full-title] Journal of the International Academy of Periodontology
  • [ISO-abbreviation] J Int Acad Periodontol
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] England
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23. Jabbour EJ, Faderl S, Kantarjian HM: Adult acute lymphoblastic leukemia. Mayo Clin Proc; 2005 Nov;80(11):1517-27
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  • [Title] Adult acute lymphoblastic leukemia.
  • Much progress has been made in understanding the biology of and therapy for acute lymphoblastic leukemia (ALL).
  • Development of new drugs and agents tailored to subset-specific cytogenetic-molecular characteristics is vital to the therapeutic success in adult ALL.
  • [MeSH-major] Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy
  • [MeSH-minor] Adult. Humans. Prognosis

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  • (PMID = 16295033.001).
  • [ISSN] 0025-6196
  • [Journal-full-title] Mayo Clinic proceedings
  • [ISO-abbreviation] Mayo Clin. Proc.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 148
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24. Yaramov N, Sokolov M, Angelov K, Petrov B, Pavlov B: [Retrorectal tumors--15 years experience and literary review]. Khirurgiia (Sofiia); 2010;(1):9-14
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  • METHODS: Patients with primary, extramucosal neoplasms occurring in the retrorectal space were identified using a retropectively maintained, procedural database of all adult colorectal surgical patients (1995-2009).
  • [MeSH-minor] Adolescent. Adult. Age Factors. Aged. Bulgaria. Female. Humans. Male. Middle Aged. Retrospective Studies. Sex Factors. Young Adult

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  • (PMID = 21972697.001).
  • [ISSN] 0450-2167
  • [Journal-full-title] Khirurgii︠a︡
  • [ISO-abbreviation] Khirurgiia (Sofiia)
  • [Language] bul
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Bulgaria
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25. Boniatti MM, Azzolini N, da Fonseca DL, Ribeiro BS, de Oliveira VM, Castilho RK, Raymundi MG, Coelho RS, Filho EM: Prognostic value of the calling criteria in patients receiving a medical emergency team review. Resuscitation; 2010 Jun;81(6):667-70
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  • The population included all adult admissions reviewed by the MET during the period between January 2007 and June 2008.

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  • [Copyright] Copyright 2010 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 20227811.001).
  • [ISSN] 1873-1570
  • [Journal-full-title] Resuscitation
  • [ISO-abbreviation] Resuscitation
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
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26. Harrison TM, Sikarskie J, Kruger J, Wise A, Mullaney TP, Kiupel M, Maes RK: Systemic calicivirus epidemic in captive exotic felids. J Zoo Wildl Med; 2007 Jun;38(2):292-9
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  • Oral ulcerations were also noted in adult African lions (Panthera leo) and Amur tigers (Panthera tigris altaica), but not in two adult snow leopards (Panthera uncia) housed in the same building.
  • All adult cats had been previously vaccinated for common feline diseases including feline calicivirus (FCV).

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  • (PMID = 17679514.001).
  • [ISSN] 1042-7260
  • [Journal-full-title] Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians
  • [ISO-abbreviation] J. Zoo Wildl. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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27. O'Kelly P, Giblin L, Spencer S, Donohoe J, Walshe JJ, Little DM, Hickey D, Cunningham P, Conlon PJ: Outcomes of adult cadaveric renal transplantation in ireland 1986 to 2001. Ir J Med Sci; 2005 Jan-Mar;174(1):42-8
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  • [Title] Outcomes of adult cadaveric renal transplantation in ireland 1986 to 2001.
  • AIMS: The aim of this study was to examine trends in outcomes and factors that influence outcomes for adult kidney transplantation from 1986 to 2001.
  • METHODS: All adult cadaveric kidney transplantations carried out between 1986 and 2001 were included.
  • [MeSH-minor] Adult. Cyclosporine / therapeutic use. Female. Histocompatibility Testing. Humans. Immunosuppressive Agents / therapeutic use. Ireland / epidemiology. Male. Postoperative Care. Proportional Hazards Models. Retrospective Studies. Risk Factors. Time Factors

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  • [Cites] Transplantation. 2002 Mar 15;73(5):775-82 [11907427.001]
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  • (PMID = 15868889.001).
  • [ISSN] 0021-1265
  • [Journal-full-title] Irish journal of medical science
  • [ISO-abbreviation] Ir J Med Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Immunosuppressive Agents; 83HN0GTJ6D / Cyclosporine
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28. Huguet F, Leguay T, Raffoux E, Thomas X, Beldjord K, Delabesse E, Chevallier P, Buzyn A, Delannoy A, Chalandon Y, Vernant JP, Lafage-Pochitaloff M, Chassevent A, Lhéritier V, Macintyre E, Béné MC, Ifrah N, Dombret H: Pediatric-inspired therapy in adults with Philadelphia chromosome-negative acute lymphoblastic leukemia: the GRAALL-2003 study. J Clin Oncol; 2009 Feb 20;27(6):911-8
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  • [Title] Pediatric-inspired therapy in adults with Philadelphia chromosome-negative acute lymphoblastic leukemia: the GRAALL-2003 study.
  • PURPOSE: Retrospective comparisons have suggested that adolescents or teenagers with acute lymphoblastic leukemia (ALL) benefit from pediatric rather than adult chemotherapy regimens.
  • Thus, the aim of the present phase II study was to test a pediatric-inspired treatment, including intensified doses of nonmyelotoxic drugs, such as prednisone, vincristine, or L-asparaginase, in adult patients with ALL up to the age of 60 years.
  • PATIENTS AND METHODS: Between 2003 and 2005, 225 adult patients (median age, 31 years; range, 15 to 60 years) with Philadelphia chromosome-negative ALL were enrolled onto the Group for Research on Adult Acute Lymphoblastic Leukemia 2003 protocol, which included several pediatric options.
  • Some adult options, such as allogeneic stem-cell transplantation for patients with high-risk ALL, were nevertheless retained.
  • RESULTS: were retrospectively compared with the historical France-Belgium Group for Lymphoblastic Acute Leukemia in Adults 94 (LALA-94) trial experience in 712 patients age 15 to 55 years.
  • CONCLUSION: These results suggest that pediatric-inspired therapy markedly improves the outcome of adult patients with ALL, at least until the age of 45 years.
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
  • [MeSH-minor] Adolescent. Adult. Female. Humans. Male. Middle Aged. Patient Selection. Philadelphia Chromosome. Retrospective Studies. Treatment Outcome. Young Adult

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  • [ErratumIn] J Clin Oncol. 2009 May 20;27(15):2574. Dosage error in article text
  • (PMID = 19124805.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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29. McLeod B, Zaver F, Avery C, Martin DP, Wang D, Jessen K, Lang ES: Matching capacity to demand: a regional dashboard reduces ambulance avoidance and improves accessibility of receiving hospitals. Acad Emerg Med; 2010 Dec;17(12):1383-9
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  • METHODS: the REPAC system provides a dashboard that synthesizes real-time capacity and acuity data for all three adult EDs in the city of Calgary, assigning a color code to reflect receiving status.
  • Primary outcomes of interest were the proportion of time spent in favorable versus unfavorable status and EMS avoidances for all adult ED sites in the region (percentage of total time with any center on EMS bypass).

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  • [Copyright] 2010 by the Society for Academic Emergency Medicine.
  • (PMID = 21122023.001).
  • [ISSN] 1553-2712
  • [Journal-full-title] Academic emergency medicine : official journal of the Society for Academic Emergency Medicine
  • [ISO-abbreviation] Acad Emerg Med
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
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30. Lord HK, Salter DM, MacDougall RH, Kerr GR: Is routine chest radiography a useful test in the follow up of all adult patients with soft tissue sarcoma? Br J Radiol; 2006 Oct;79(946):799-800
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  • [Title] Is routine chest radiography a useful test in the follow up of all adult patients with soft tissue sarcoma?
  • Adult patients on routine follow up between 1994 and 2004 were identified and the notes of those with lung metastases reviewed.
  • [MeSH-minor] Adult. Follow-Up Studies. Humans. Neoplasm Recurrence, Local / radiography. Prognosis. Risk Factors


31. Chen PM, Yen CC, Yang MH, Poh SB, Hsiao LT, Wang WS, Lin PC, Lee MY, Teng HW, Bai LY, Chu CJ, Chao SC, Yang AH, Chiou TJ, Liu JH, Chao TC: High prevalence of SV40 infection in patients with nodal non-Hodgkin's lymphoma but not acute leukemia independent of contaminated polio vaccines in Taiwan. Cancer Invest; 2006 Apr-May;24(3):223-8
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  • [Title] High prevalence of SV40 infection in patients with nodal non-Hodgkin's lymphoma but not acute leukemia independent of contaminated polio vaccines in Taiwan.
  • All other test samples, including diagnostic bone marrow from patients with acute leukemia, peripheral blood from 10 relatives of SV40 positive-patients and 91 age-matched normal volunteers, and 5 reactive hyperplastic lymphoid tissues, showed negative.
  • [MeSH-minor] Acute Disease. Adolescent. Adult. Aged. Aged, 80 and over. Antigens, Polyomavirus Transforming / analysis. Blotting, Southern. Bone Marrow Cells / virology. Female. Humans. Leukemia / virology. Lymph Nodes / virology. Male. Middle Aged. Polymerase Chain Reaction. Prevalence. Taiwan. Tumor Virus Infections / epidemiology

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  • (PMID = 16809147.001).
  • [ISSN] 0735-7907
  • [Journal-full-title] Cancer investigation
  • [ISO-abbreviation] Cancer Invest.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Polyomavirus Transforming; 0 / Poliovirus Vaccines
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32. Lupien M, Diévart A, Morales CR, Hermo L, Calvo E, Kay DG, Hu C, Jolicoeur P: Expression of constitutively active Notch1 in male genital tracts results in ectopic growth and blockage of efferent ducts, epididymal hyperplasia and sterility. Dev Biol; 2006 Dec 15;300(2):497-511
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  • In contrast, in adult Tg mice from day 38 onwards, the efferent ducts, the vas deferens and most epididymal segments revealed bilateral epithelial cell hyperplasia with absence of fully differentiated epithelial cells.
  • In adult Tg testis, the different generations of germ cells of seminiferous tubules appeared normal, although some tubules were highly dilated and revealed an absence of early and/or late spermatids.
  • Consistent with a blockage of efferent ducts often seen at the rete testis/efferent duct interface, spermatozoa were absent in epididymis of all adult Tg mice and in all highly hyperplastic efferent duct tubules of these Tg mice.


33. Ahmed SN, Unterman J, McCloskey B, Sinclair DB: Clinical significance of photic stimulation during routine EEGs of adult patients. Am J Electroneurodiagnostic Technol; 2006 Dec;46(4):356-62
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  • [Title] Clinical significance of photic stimulation during routine EEGs of adult patients.
  • There is insufficient clinical data to advocate IPS in the routine EEGs of all adult patients.
  • We therefore sought to address the clinical significance of routine IPS in the adult population.
  • We retrospectively reviewed 100 consecutive abnormal EEGs in adult patients (inpatients and outpatients) who had undergone photic stimulation in our laboratory.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Reproducibility of Results. Retrospective Studies. Sensitivity and Specificity

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  • (PMID = 17285818.001).
  • [ISSN] 1086-508X
  • [Journal-full-title] American journal of electroneurodiagnostic technology
  • [ISO-abbreviation] Am J Electroneurodiagnostic Technol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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34. Vitale A, Guarini A, Chiaretti S, Foà R: The changing scene of adult acute lymphoblastic leukemia. Curr Opin Oncol; 2006 Nov;18(6):652-9
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  • [Title] The changing scene of adult acute lymphoblastic leukemia.
  • PURPOSE OF REVIEW: The review focuses on the most recent advances in the diagnostic and prognostic work-up of adult acute lymphoblastic leukemia (ALL) and its implications in the clinical management of the disease.
  • SUMMARY: Recent biologic advancements are progressively realising the possibility of designing targeted and individualized therapeutic strategies according to the more refined, molecularly defined features of leukemic cells and the presence or absence of residual disease in adult ALL.
  • [MeSH-major] Precursor Cell Lymphoblastic Leukemia-Lymphoma
  • [MeSH-minor] Adult. Gene Expression Profiling. Gene Expression Regulation, Neoplastic. Humans. Neoplasm, Residual / diagnosis. Neoplasm, Residual / therapy

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  • (PMID = 16988590.001).
  • [ISSN] 1531-703X
  • [Journal-full-title] Current opinion in oncology
  • [ISO-abbreviation] Curr Opin Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 104
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35. Landau H, Weiss MA: Clinical trials report. Minimal residual disease quantification in adult acute lymphoblastic leukemia. Curr Oncol Rep; 2006 Sep;8(5):323-4
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  • [Title] Clinical trials report. Minimal residual disease quantification in adult acute lymphoblastic leukemia.

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36. Chung W, Kim H, Lim S, Lee S, Cho K: Factors influencing cigarette smoking and quantified implications for anti-smoking policy: evidence from South Korea. Int J Public Health; 2009;54(6):409-19
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVES: The aim of this study was to determine the factors that are associated with adult males' smoking in South Korea and simulate the effects of a potential anti-smoking policy.
  • Compared to the current state, a policy package consisting of mutually reinforcing measures could reduce the probability of smoking and the average number of cigarettes consumed among all adult males by 34 and 51%, respectively.
  • [MeSH-minor] Adult. Cross-Sectional Studies. Female. Humans. Likelihood Functions. Male. Middle Aged. Public Health. Republic of Korea. Risk Factors. Risk-Taking. Young Adult

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  • [ISSN] 1661-8564
  • [Journal-full-title] International journal of public health
  • [ISO-abbreviation] Int J Public Health
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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37. Romano ME, Wahlander SB, Lang BH, Li G, Prager KM: Mandatory ethics consultation policy. Mayo Clin Proc; 2009 Jul;84(7):581-5
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  • PATIENTS AND METHODS: We retrospectively reviewed the medical records of all adult patients who were admitted to the intensive care unit at Columbia University Medical Center and had an ethics consultation between August 1, 2006, and July 31, 2007.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Cohort Studies. Female. Hospital Mortality. Humans. Male. Middle Aged. Program Evaluation. Retrospective Studies. Terminal Care / ethics. Withholding Treatment / ethics. Young Adult

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  • (PMID = 19567711.001).
  • [ISSN] 1942-5546
  • [Journal-full-title] Mayo Clinic proceedings
  • [ISO-abbreviation] Mayo Clin. Proc.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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38. Sharp KH, Eam B, Faulkner DJ, Haygood MG: Vertical transmission of diverse microbes in the tropical sponge Corticium sp. Appl Environ Microbiol; 2007 Jan;73(2):622-9
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  • Three selected bacterial taxa, representing proteobacteria, actinobacteria, and a clade including recently described sponge-associated bacteria, were tested and found to be present in all adult samples tested over a 3-year period and in the embryos throughout development.

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  • (PMID = 17122394.001).
  • [ISSN] 0099-2240
  • [Journal-full-title] Applied and environmental microbiology
  • [ISO-abbreviation] Appl. Environ. Microbiol.
  • [Language] ENG
  • [Databank-accession-numbers] GENBANK/ DQ247938/ DQ247939/ DQ247940/ DQ247941/ DQ247942/ DQ247943/ DQ247944/ DQ247945/ DQ247946/ DQ247947/ DQ247948/ DQ247949/ DQ247950/ DQ247951/ DQ247952/ DQ247953/ DQ247954/ DQ247955/ DQ247956/ DQ247957
  • [Grant] United States / NCI NIH HHS / CA / R01 CA079678; United States / NCI NIH HHS / CA / 5R01CA079678-03
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Archaeal; 0 / DNA, Bacterial; 0 / RNA, Ribosomal, 16S
  • [Other-IDs] NLM/ PMC1796987
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39. Kos MI, Degive C, Boex C, Guyot JP: Professional occupation after cochlear implantation. J Laryngol Otol; 2007 Mar;121(3):215-8
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  • All adult patients received a questionnaire concerning their professional activities before and after implantation.
  • [MeSH-minor] Adolescent. Adult. Aged. Career Mobility. Female. Health Status. Hearing Tests. Humans. Male. Middle Aged. Patient Satisfaction. Treatment Outcome

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  • (PMID = 17052367.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] England
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40. Jmili NB, Souguir S, Yacoub S, Khelif A, Kortas M: [Study of antigenic profile of blasts in acute lymphoblastic leukemia: flow cytometric analysis of 152 cases]. Ann Biol Clin (Paris); 2009 Sep-Oct;67(5):543-51
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  • [Title] [Study of antigenic profile of blasts in acute lymphoblastic leukemia: flow cytometric analysis of 152 cases].
  • The aim of this study was to characterize the antigenic profile of blasts in acute lymphoblastic leukaemia (ALL) and to determine possible phenotypic aberrancies in a series of 152 patients with acute leukaemia diagnosed non myeloid leukaemia in cytology.
  • Based on criteria of EGIL (European Group of Immunological Leukaemia), cases were classified as: acute lymphoblastic leukaemia (ALL, 52,6%); 75% cases of ALL belong to lymphoid B lineage.
  • In 10,5% of cases, biphenotypic leukaemia is diagnosed (lymphoid/myeloid).
  • Flow cytometry has wide field of applications to characterize blast cells from patients with acute leukaemia: to establish diagnosis of lineage responsible in proliferation, to determine the stage of maturation, to predict prognosis for a better adaptation of adequate treatment, to follow evolution of disease after chemotherapy and to study minimal residual disease.
  • [MeSH-major] Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Female. Flow Cytometry. Humans. Immunophenotyping. Infant. Male. Middle Aged. Neprilysin / analysis. Young Adult

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  • (PMID = 19789126.001).
  • [ISSN] 0003-3898
  • [Journal-full-title] Annales de biologie clinique
  • [ISO-abbreviation] Ann. Biol. Clin. (Paris)
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] EC 3.4.24.11 / Neprilysin
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41. Stringaris K, Adams S, Uribe M, Eniafe R, Wu CO, Savani BN, Barrett AJ: Donor KIR Genes 2DL5A, 2DS1 and 3DS1 are associated with a reduced rate of leukemia relapse after HLA-identical sibling stem cell transplantation for acute myeloid leukemia but not other hematologic malignancies. Biol Blood Marrow Transplant; 2010 Sep;16(9):1257-64
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  • [Title] Donor KIR Genes 2DL5A, 2DS1 and 3DS1 are associated with a reduced rate of leukemia relapse after HLA-identical sibling stem cell transplantation for acute myeloid leukemia but not other hematologic malignancies.
  • Elimination of malignant cells through a graft-versus-leukemia (GVL) effect involves donor T and natural killer (NK) cells, but their relative contribution to this process is poorly defined.
  • Univariate and multivariate analysis of transplant-related risk factors and KIR genotyping was performed to identify independent variables predictive of outcome for different forms of leukemia.
  • Further to confirming known predictive factors for TRM and survival (CD34 cell dose, patient age, disease stage), statistical analysis revealed that 3 donor B haplotype KIR genes, 2DL5A, 2DS1, and 3DS1, were associated with significantly less relapse in patients with acute myelogenous leukemia (AML) (13% versus 57%) but not in patients with other myelogenous or lymphoid malignancies.
  • [MeSH-major] HLA Antigens / immunology. Hematologic Neoplasms / genetics. Hematologic Neoplasms / therapy. Leukemia, Myeloid, Acute / genetics. Leukemia, Myeloid, Acute / therapy. Receptors, KIR / genetics. Stem Cell Transplantation / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Cohort Studies. Female. Histocompatibility Testing. Humans. Male. Middle Aged. Multivariate Analysis. Risk Factors. Siblings. Tissue Donors. Treatment Outcome. Young Adult

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  • [Copyright] Published by Elsevier Inc.
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  • (PMID = 20302958.001).
  • [ISSN] 1523-6536
  • [Journal-full-title] Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
  • [ISO-abbreviation] Biol. Blood Marrow Transplant.
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / / ZIA HL006105-02
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / HLA Antigens; 0 / Receptors, KIR
  • [Other-IDs] NLM/ NIHMS207885; NLM/ PMC3801172
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42. Thomas D, O'Brien S, Faderl S, Ravandi F, Jabbour E, Pierce S, Cortes J, Kantarjian H: Anthracycline dose intensification in adult acute lymphoblastic leukemia: lack of benefit in the context of the fractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone regimen. Cancer; 2010 Oct 1;116(19):4580-9
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  • [Title] Anthracycline dose intensification in adult acute lymphoblastic leukemia: lack of benefit in the context of the fractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone regimen.
  • BACKGROUND: In previous studies of frontline therapy for adult acute lymphoblastic leukemia (ALL), early treatment with higher doses of anthracyclines has been reported to improve outcome.
  • METHODS: Sixty-eight consecutive adults with de novo ALL or lymphoblastic lymphoma were treated with this modified hyper-CVAD regimen inclusive of rituximab for CD20 expression≥20%.
  • CONCLUSIONS: In the context of the hyper-CVAD regimen, early anthracycline intensification did not improve outcome for adults with de novo ALL or lymphoblastic lymphoma.
  • [MeSH-major] Anthracyclines / administration & dosage. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Daunorubicin / administration & dosage. Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Cyclophosphamide / administration & dosage. Cytarabine / administration & dosage. Dexamethasone / administration & dosage. Doxorubicin / administration & dosage. Drug Administration Schedule. Humans. Methotrexate / administration & dosage. Middle Aged. Salvage Therapy. Treatment Outcome. Vincristine / administration & dosage

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  • [Copyright] Copyright © 2010 American Cancer Society.
  • (PMID = 20572037.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA016672
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anthracyclines; 04079A1RDZ / Cytarabine; 5J49Q6B70F / Vincristine; 7S5I7G3JQL / Dexamethasone; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; YL5FZ2Y5U1 / Methotrexate; ZS7284E0ZP / Daunorubicin; CVAD protocol
  • [Other-IDs] NLM/ NIHMS652593; NLM/ PMC4458382
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43. Wapenaar W, Barkema HW, O'Handley RM, Bartels CJ: Use of an enzyme-linked immunosorbent assay in bulk milk to estimate the prevalence of Neospora caninum on dairy farms in Prince Edward Island, Canada. Can Vet J; 2007 May;48(5):493-9
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  • In 11 farms that were considered positive based on bulk milk samples, blood samples were collected from all adult cows in September 2005, in conjunction with a 4th bulk milk sample on the same day.

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  • (PMID = 17542367.001).
  • [ISSN] 0008-5286
  • [Journal-full-title] The Canadian veterinary journal = La revue vétérinaire canadienne
  • [ISO-abbreviation] Can. Vet. J.
  • [Language] eng
  • [Publication-type] Journal Article; Validation Studies
  • [Publication-country] Canada
  • [Chemical-registry-number] 0 / Antibodies, Protozoan
  • [Other-IDs] NLM/ PMC1852591
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44. Bampton PA, Schloithe A, Bull J, Fraser RJ, Padbury RT, Watson DI: Improving surveillance for Barrett's oesophagus. BMJ; 2006 Jun 3;332(7553):1320-3
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  • All adult patients diagnosed with Barrett's oesophagus were included.
  • [MeSH-minor] Adult. Guideline Adherence. Humans. Mass Screening / methods. Medical Audit. Practice Guidelines as Topic. Retrospective Studies. South Australia


45. Chiaretti S, Li X, Gentleman R, Vitale A, Wang KS, Mandelli F, Foà R, Ritz J: Gene expression profiles of B-lineage adult acute lymphocytic leukemia reveal genetic patterns that identify lineage derivation and distinct mechanisms of transformation. Clin Cancer Res; 2005 Oct 15;11(20):7209-19
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  • [Title] Gene expression profiles of B-lineage adult acute lymphocytic leukemia reveal genetic patterns that identify lineage derivation and distinct mechanisms of transformation.
  • PURPOSE: To characterize gene expression signatures in acute lymphocytic leukemia (ALL) cells associated with known genotypic abnormalities in adult patients.
  • EXPERIMENTAL DESIGN: Gene expression profiles from 128 adult patients with newly diagnosed ALL were characterized using high-density oligonucleotide microarrays.
  • We also identified a set of 83 genes that were highly expressed in leukemia blasts from patients without known molecular abnormalities who subsequently relapsed following therapy.
  • CONCLUSIONS: Genomic signatures are associated with phenotypically and molecularly well defined subgroups of adult ALL.
  • Genomic profiling also identifies genes associated with poor outcome in cases without molecular aberrations and specific genes that may be new therapeutic targets in adult ALL.
  • [MeSH-major] Burkitt Lymphoma / genetics. Gene Expression Profiling. Gene Expression Regulation, Leukemic / genetics. Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics
  • [MeSH-minor] Adolescent. Adult. Cluster Analysis. Cytogenetic Analysis. Female. Flow Cytometry / methods. Humans. Immunophenotyping. Italy. Karyotyping. Male. Middle Aged. Oligonucleotide Array Sequence Analysis / methods. Oncogene Proteins, Fusion / genetics

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  • (PMID = 16243790.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA66996
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Oncogene Proteins, Fusion
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46. Matteucci C, Barba G, Varasano E, Vitale A, Mancini M, Testoni N, Cuneo A, Rege-Cambrin G, Elia L, La Starza R, Pierini V, Brandimarte L, Vignetti M, Foà R, Mecucci C, GIMEMA Acute Leukaemia Working Party, Italy: Rescue of genomic information in adult acute lymphoblastic leukaemia (ALL) with normal/failed cytogenetics: a GIMEMA centralized biological study. Br J Haematol; 2010 Apr;149(1):70-8
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  • [Title] Rescue of genomic information in adult acute lymphoblastic leukaemia (ALL) with normal/failed cytogenetics: a GIMEMA centralized biological study.
  • Metaphase (M-) and array (A-) Comparative Genomic Hybridization (CGH) were used to investigate 40 cases of T- and 32 of B-cell acute lymphoblastic leukaemia (ALL) with normal/failed cytogenetics.
  • [MeSH-major] Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics
  • [MeSH-minor] Adolescent. Adult. Chromosomes, Human, Pair 17 / genetics. Comparative Genomic Hybridization. Female. Gene Deletion. Genes, Neurofibromatosis 1. Genome. Humans. In Situ Hybridization, Fluorescence / methods. Male. Metaphase / genetics. Middle Aged. Prognosis. Young Adult

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  • (PMID = 20067559.001).
  • [ISSN] 1365-2141
  • [Journal-full-title] British journal of haematology
  • [ISO-abbreviation] Br. J. Haematol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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47. Chew KS, Idzwan ZM, Hisamuddin NA, Kamaruddin J, Wan Aasim WA: Outcomes of cardiopulmonary resuscitation performed in Emergency Department, Hospital Universiti Sains Malaysia. Med J Malaysia; 2008 Mar;63(1):4-8
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  • All adult cardiac arrest cases with CPR performed in ED, HUSM were included in the survey.

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  • (PMID = 18935723.001).
  • [ISSN] 0300-5283
  • [Journal-full-title] The Medical journal of Malaysia
  • [ISO-abbreviation] Med. J. Malaysia
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Malaysia
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48. Hewson KM, Burrell AR: A pilot study to test the use of a checklist in a tertiary intensive care unit as a method of ensuring quality processes of care. Anaesth Intensive Care; 2006 Jun;34(3):322-8
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  • Checklists were completed on the morning round for all adult patients admitted to the unit for approximately one month.
  • [MeSH-minor] Adult. Humans. Intensive Care Units. Medical Errors / prevention & control. Outcome and Process Assessment (Health Care). Pilot Projects

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  • [ErratumIn] Anaesth Intensive Care. 2006 Aug;34(4):528
  • (PMID = 16802484.001).
  • [ISSN] 0310-057X
  • [Journal-full-title] Anaesthesia and intensive care
  • [ISO-abbreviation] Anaesth Intensive Care
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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49. Sun HM, Qian SX, Wu YJ, Qiao C, Hong M, Fan L, Yang H, Zhang JF, Zhang SJ, Wu HX, Qiu HX, Lu H, Xu W, Sheng RL, Li JY: [Immunophenotypic features in 143 cases of acute promyelocytic leukemia]. Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2009 Feb;17(1):176-9
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  • [Title] [Immunophenotypic features in 143 cases of acute promyelocytic leukemia].
  • This study was aimed to investigate the immunophenotypic characteristics of acute promyelocytic leukemia (APL).
  • (2) the positive rate of CD33 in newly diagnosed APL group was higher than that in other groups (97.0% vs 75.0%, 83.3%, 83.9%), as well as the the positive level of CD33 (p < 0.05). (3) no lymphoid antigen other than CD2 was expressed in newly diagnosed APL group.
  • For those patients with DR(-) AML, it may be helpful to identify APL depending on following features: low or negative CD34 expression, homogeneous and bright expression of CD33, no lymphoid antigens other than CD2, higher SSC.

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  • (PMID = 19236773.001).
  • [ISSN] 1009-2137
  • [Journal-full-title] Zhongguo shi yan xue ye xue za zhi
  • [ISO-abbreviation] Zhongguo Shi Yan Xue Ye Xue Za Zhi
  • [Language] CHI
  • [Publication-type] English Abstract; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD34; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD33 protein, human; 0 / HLA-DR Antigens; 0 / Sialic Acid Binding Ig-like Lectin 3
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50. Ravindran V, Logan I, Bourke BE: Septic arthritis: clinical audits would help optimise the management. Clin Rheumatol; 2008 Dec;27(12):1565-7
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  • All adult patients who were admitted to our institution between January 2005 and December 2006 with symptoms and signs of SA and had positive synovial fluid culture were included, and a structured proforma was used to extract the relevant information from the case notes and laboratory tests.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Clinical Competence. Female. Hospitals, Teaching. Humans. Internship and Residency. Male. Middle Aged. Practice Guidelines as Topic. United Kingdom

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  • [Cites] Rheumatology (Oxford). 2006 Aug;45(8):1039-41 [16829534.001]
  • [Cites] Rheumatology (Oxford). 2008 Jun;47(6):927-8 [18413344.001]
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  • (PMID = 18795395.001).
  • [ISSN] 1434-9949
  • [Journal-full-title] Clinical rheumatology
  • [ISO-abbreviation] Clin. Rheumatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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51. Pérez Fentes DA, Blanco Parra M, Toucedo Caamaño V, Lema Grille J, Cimadevila García A, Villar Núñez M: [Atypical sites of metastatic renal carcinoma. Literature review]. Actas Urol Esp; 2005 Jul-Aug;29(7):621-30
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  • CONCLUSIONS: Renal cell carcinoma represents about 3% of all adult malignancy neoplasms.

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  • (PMID = 16180312.001).
  • [ISSN] 0210-4806
  • [Journal-full-title] Actas urologicas espanolas
  • [ISO-abbreviation] Actas Urol Esp
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 19
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52. Hasegawa H, Sawa H, Lewis MJ, Orba Y, Sheehy N, Yamamoto Y, Ichinohe T, Tsunetsugu-Yokota Y, Katano H, Takahashi H, Matsuda J, Sata T, Kurata T, Nagashima K, Hall WW: Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus type I. Nat Med; 2006 Apr;12(4):466-72
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  • [Title] Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus type I.
  • Adult T-cell leukemia-lymphoma (ATLL) is a group of T-cell malignancies caused by infection with human T-lymphotropic virus type I (HTLV-I).
  • After prolonged latency periods, transgenic mice developed diffuse large-cell lymphomas and leukemia with clinical, pathological and immunological features characteristic of acute ATLL.
  • [MeSH-major] Genes, pX. Human T-lymphotropic virus 1 / genetics. Leukemia, Lymphoid / pathology. Thymus Neoplasms / pathology


53. Kim SJ, Gill JS: H-Y incompatibility predicts short-term outcomes for kidney transplant recipients. J Am Soc Nephrol; 2009 Sep;20(9):2025-33
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  • In an attempt to confirm and extend these results, we studied all adult recipients of deceased-donor kidney transplants from 1990 through 2004 in the US Renal Data System.
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Follow-Up Studies. Histocompatibility / immunology. Humans. Isoantibodies / immunology. Kaplan-Meier Estimate. Male. Middle Aged. Proportional Hazards Models. Risk Factors. Sex Distribution. Tissue Donors / statistics & numerical data. Young Adult

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  • [Cites] Nephrol Dial Transplant. 2007 Dec;22(12):3646-51 [17704114.001]
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  • (PMID = 19541808.001).
  • [ISSN] 1533-3450
  • [Journal-full-title] Journal of the American Society of Nephrology : JASN
  • [ISO-abbreviation] J. Am. Soc. Nephrol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / H-Y Antigen; 0 / H-Y antibody; 0 / Isoantibodies
  • [Other-IDs] NLM/ PMC2736773
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54. Cohen S, Leshanski L, Itskovitz-Eldor J: Tissue engineering using human embryonic stem cells. Methods Enzymol; 2006;420:303-15
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  • Stem cells have the ability to rejuvenate and repair damaged tissues and can be derived from both embryonic and adult sources.
  • Isolated from the inner cell mass of preimplantation stage blastocysts, they possess the ability to differentiate into practically all adult cell types.

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  • (PMID = 17161703.001).
  • [ISSN] 0076-6879
  • [Journal-full-title] Methods in enzymology
  • [ISO-abbreviation] Meth. Enzymol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Culture Media
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55. Tober DM, Taghdisi MH, Jalali M: "Fewer children, better life" or "as many as God wants"? Family planning among low-income Iranian and Afghan refugee families in Isfahan, Iran. Med Anthropol Q; 2006 Mar;20(1):50-71
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  • On these occasions, all adult married patients are strongly encouraged to use family planning to reduce the number of offspring.
  • [MeSH-minor] Adolescent. Adult. Afghanistan / ethnology. Child. Child, Preschool. Family Characteristics / ethnology. Family Planning Services / organization & administration. Family Planning Services / utilization. Female. Humans. Iran / epidemiology. Male. Middle Aged. Public Health Practice

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  • (PMID = 16612993.001).
  • [ISSN] 0745-5194
  • [Journal-full-title] Medical anthropology quarterly
  • [ISO-abbreviation] Med Anthropol Q
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
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56. Strömquist A, Fahlman A, Arnemo JM, Pettersson A: Dental and periodontal health in free-ranging Swedish brown bears (Ursus arctos). J Comp Pathol; 2009 Aug-Oct;141(2-3):170-6
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  • All adult bears were missing one or more premolars.

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  • (PMID = 19539950.001).
  • [ISSN] 1532-3129
  • [Journal-full-title] Journal of comparative pathology
  • [ISO-abbreviation] J. Comp. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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57. Awan Z, Alrasadi K, Francis GA, Hegele RA, McPherson R, Frohlich J, Valenti D, de Varennes B, Marcil M, Gagne C, Genest J, Couture P: Vascular calcifications in homozygote familial hypercholesterolemia. Arterioscler Thromb Vasc Biol; 2008 Apr;28(4):777-85
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  • CONCLUSIONS: We document premature severe aortic calcifications in all adult hmzFH patients studied.
  • [MeSH-minor] Adolescent. Adult. Canada. Child. Child, Preschool. Cholesterol, LDL / blood. Ethnic Groups / genetics. Female. Follow-Up Studies. Homozygote. Humans. Male. Middle Aged. Mutation. Receptors, LDL / genetics

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  • [CommentIn] Arterioscler Thromb Vasc Biol. 2008 Apr;28(4):606-7 [18354092.001]
  • (PMID = 18239150.001).
  • [ISSN] 1524-4636
  • [Journal-full-title] Arteriosclerosis, thrombosis, and vascular biology
  • [ISO-abbreviation] Arterioscler. Thromb. Vasc. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cholesterol, LDL; 0 / Receptors, LDL
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58. Lidove O, Bekri S, Goizet C, Khau Van Kien A, Aractingi S, Knebelmann B, Choukroun G, Tsimaratos M, Redonnet-Vernhet I, Lacombe D, Jaussaud R: [Fabry disease: proposed guidelines from a French expert group for its diagnosis, treatment and follow-up]. Presse Med; 2007 Jul-Aug;36(7-8):1084-97
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  • Enzyme replacement therapy should be considered in all adult male patients and should probably begin early.
  • In adult heterozygous female patients and in children, this treatment should be considered only for patients with severe pain, organ damage, or central nervous system, kidney, or heart involvement.

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  • (PMID = 17276649.001).
  • [ISSN] 0755-4982
  • [Journal-full-title] Presse medicale (Paris, France : 1983)
  • [ISO-abbreviation] Presse Med
  • [Language] fre
  • [Publication-type] Journal Article; Review
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Isoenzymes; 2HLC17MX9G / agalsidase alfa; EC 3.2.1.22 / alpha-Galactosidase; RZD65TSM9U / agalsidase beta
  • [Number-of-references] 67
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59. de Vallière S, Barker RD: Poor performance status is associated with early death in patients with pulmonary tuberculosis. Trans R Soc Trop Med Hyg; 2006 Jul;100(7):681-6
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  • During 3 months in 2001, all adult patients admitted to eight hospitals in Limpopo Province, South Africa, and diagnosed with PTB were eligible for inclusion.
  • [MeSH-minor] Activities of Daily Living. Adult. Age Distribution. Aged. Aged, 80 and over. Epidemiologic Methods. Exercise. Female. Humans. Male. Middle Aged. Self Care. Sex Distribution. South Africa / epidemiology. Time Factors

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  • (PMID = 16313934.001).
  • [ISSN] 0035-9203
  • [Journal-full-title] Transactions of the Royal Society of Tropical Medicine and Hygiene
  • [ISO-abbreviation] Trans. R. Soc. Trop. Med. Hyg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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60. Kulshrestha R, Sah SP: Pattern of occurrence of leukemia at a teaching hospital in eastern region of Nepal - a six year study. JNMA J Nepal Med Assoc; 2009 Jan-Mar;48(173):35-40
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  • [Title] Pattern of occurrence of leukemia at a teaching hospital in eastern region of Nepal - a six year study.
  • INTRODUCTION: Pattern of leukemia is known to vary widely throughout the world.
  • The characterization of distribution patterns of different subtypes of leukemia in Nepal needs further study.
  • We wanted to study the leukemia pattern in our institute.
  • METHODS: A retrospective study of 196 cases of leukemia, diagnosed at BPKIHS, between January 1997 to December 2002 was done.
  • We analyzed the pattern of leukemia at BPKIHS by morphological subtype, gender, age at diagnosis, time period of diagnosis (seasonality), and geographic distribution.
  • RESULTS: Morphological sub typing showed that 121 cases were of acute leukemia and 75 of chronic leukemia.
  • Chronic myeloid leukemia constituted the single largest group comprising 35.2 % of all cases, followed by acute myeloid leukemia (28.57 %) and acute lymphoid leukemia (19.9 %).
  • This is the second series of leukemia from Nepal.
  • CONCLUSIONS: The data published in this study reflects the leukemia pattern in the eastern region of Nepal.
  • [MeSH-major] Hospitals, Teaching / statistics & numerical data. Leukemia / epidemiology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Female. Humans. Incidence. Infant. Infant, Newborn. Male. Middle Aged. Nepal / epidemiology. Retrospective Studies. Seasons. Young Adult

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  • (PMID = 19529056.001).
  • [ISSN] 0028-2715
  • [Journal-full-title] JNMA; journal of the Nepal Medical Association
  • [ISO-abbreviation] JNMA J Nepal Med Assoc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nepal
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61. Musich D, Busch MJ: Early orthodontic treatment: current clinical perspectives. Alpha Omegan; 2007;100(1):17-24
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  • Orthodontic intervention before all adult teeth erupt improves long-term stability (Figures 6-8).

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  • (PMID = 17566300.001).
  • [ISSN] 0002-6417
  • [Journal-full-title] The Alpha omegan
  • [ISO-abbreviation] Alpha Omegan
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
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62. Fahim F, Al Salamah SM: Cystic echinococcosis in Central Saudi Arabia: a 5-year experience. Turk J Gastroenterol; 2007 Mar;18(1):22-7
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  • All adult patients admitted with the primary or incidental diagnosis of echinococcosis were included.
  • [MeSH-minor] Abdominal Pain / etiology. Adolescent. Adult. Aged. Aged, 80 and over. Albendazole / therapeutic use. Antiprotozoal Agents / therapeutic use. Cough / etiology. Eosinophilia / epidemiology. Female. Fever / etiology. Hemagglutination Inhibition Tests. Humans. Jaundice / etiology. Leukocytosis / etiology. Male. Mebendazole / therapeutic use. Middle Aged. Rupture. Saudi Arabia / epidemiology. Young Adult

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  • (PMID = 17450491.001).
  • [ISSN] 2148-5607
  • [Journal-full-title] The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
  • [ISO-abbreviation] Turk J Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Turkey
  • [Chemical-registry-number] 0 / Antiprotozoal Agents; 81G6I5V05I / Mebendazole; F4216019LN / Albendazole
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63. Malik HS, Henikoff S: Positive selection of Iris, a retroviral envelope-derived host gene in Drosophila melanogaster. PLoS Genet; 2005 Oct;1(4):e44
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  • Here, we show that in Drosophila genomes, a previously unannotated gene (CG4715, renamed Iris) was domesticated from a novel, active Kanga lineage of insect retroviruses at least 25 million years ago, and has since been maintained as a host gene that is expressed in all adult tissues.

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  • (PMID = 16244705.001).
  • [ISSN] 1553-7404
  • [Journal-full-title] PLoS genetics
  • [ISO-abbreviation] PLoS Genet.
  • [Language] eng
  • [Databank-accession-numbers] GENBANK/ DQ177366/ DQ177367/ DQ177368/ DQ177369/ DQ177370/ DQ177371/ DQ177372/ DQ177373/ DQ177374/ DQ177375/ DQ177376/ DQ177377/ DQ177378/ DQ177379/ DQ177380/ DQ177381/ DQ177382/ DQ177383/ DQ177384/ DQ177385/ DQ177386/ DQ177387/ DQ177388/ DQ177389/ DQ177390/ DQ177391/ DQ177392/ DQ177393/ DQ177394/ DQ177395/ DQ177396/ DQ177397/ DQ177398/ DQ177399/ DQ177400/ DQ177401/ DQ177402/ DQ177403/ DQ177404/ DQ177405/ DQ177406/ DQ177407/ DQ177408/ DQ177409/ DQ177410/ DQ177411/ DQ177412/ DQ177413/ DQ177414/ DQ177415/ DQ177416/ DQ177417/ DQ177418/ DQ185599/ DQ185600/ DQ185601/ DQ185602
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Drosophila Proteins; 0 / Iris protein, Drosophila; 0 / Ligands; 0 / Retroelements
  • [Other-IDs] NLM/ PMC1262188
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64. Gemmati D, De Mattei M, Catozzi L, Della Porta M, Serino ML, Ambrosio C, Cuneo A, Friso S, Krampera M, Orioli E, Zeri G, Ongaro A: DHFR 19-bp insertion/deletion polymorphism and MTHFR C677T in adult acute lymphoblastic leukaemia: is the risk reduction due to intracellular folate unbalancing? Am J Hematol; 2009 Aug;84(8):526-9
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  • [Title] DHFR 19-bp insertion/deletion polymorphism and MTHFR C677T in adult acute lymphoblastic leukaemia: is the risk reduction due to intracellular folate unbalancing?
  • [MeSH-major] Folic Acid / genetics. Genetic Predisposition to Disease. INDEL Mutation. Methylenetetrahydrofolate Dehydrogenase (NAD+) / genetics. Neoplasm Proteins / genetics. Polymorphism, Genetic. Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics. Tetrahydrofolate Dehydrogenase / genetics
  • [MeSH-minor] Adult. Aged. Humans. Italy. Middle Aged

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  • (PMID = 19536847.001).
  • [ISSN] 1096-8652
  • [Journal-full-title] American journal of hematology
  • [ISO-abbreviation] Am. J. Hematol.
  • [Language] eng
  • [Publication-type] Letter; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Neoplasm Proteins; 935E97BOY8 / Folic Acid; EC 1.5.1.15 / Methylenetetrahydrofolate Dehydrogenase (NAD+); EC 1.5.1.3 / Tetrahydrofolate Dehydrogenase
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65. Avilés A, Neri N, Nambo MJ, Huerta-Guzman J, Cleto S: Surgery and chemotherapy versus chemotherapy as treatment of high-grade MALT gastric lymphoma. Med Oncol; 2006;23(2):295-300
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  • BACKGROUND AND OBJECTIVES: Treatment of high-grade MALT (mucosa-associated lymphoid tissue) gastric lymphoma remains uncertain.
  • Acute and late toxicity were mild and well controlled.
  • No acute leukemia or second neoplasm has been observed.
  • [MeSH-minor] Adult. Aged. Bleomycin / administration & dosage. Cyclophosphamide / administration & dosage. Disease-Free Survival. Epirubicin / administration & dosage. Female. Humans. Male. Middle Aged. Neoplasm Staging. Prednisone / administration & dosage. Remission Induction. Vincristine / administration & dosage

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  • (PMID = 16720930.001).
  • [ISSN] 1357-0560
  • [Journal-full-title] Medical oncology (Northwood, London, England)
  • [ISO-abbreviation] Med. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial
  • [Publication-country] United States
  • [Chemical-registry-number] 11056-06-7 / Bleomycin; 3Z8479ZZ5X / Epirubicin; 5J49Q6B70F / Vincristine; 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone; CEOP-B protocol
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66. Ayala RM, Martínez-López J, Albízua E, Diez A, Gilsanz F: Clinical significance of Gata-1, Gata-2, EKLF, and c-MPL expression in acute myeloid leukemia. Am J Hematol; 2009 Feb;84(2):79-86
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  • [Title] Clinical significance of Gata-1, Gata-2, EKLF, and c-MPL expression in acute myeloid leukemia.
  • The aim of this study was to evaluate the biological correlation and prognostic impact of Gata-1, Gata-2, EKLF, and c-MPL transcript level in a group of 41 acute myeloid leukemia (AML) patients.
  • Gata-1 overexpression was related to advanced age and a low percentage of bone marrow blasts and was associated with the expression of CD34 antigen and lymphoid T markers.
  • [MeSH-major] GATA1 Transcription Factor / physiology. GATA2 Transcription Factor / physiology. Gene Expression Regulation, Neoplastic. Kruppel-Like Transcription Factors / physiology. Leukemia, Myeloid, Acute / genetics. Neoplasm Proteins / physiology. Receptors, Thrombopoietin / physiology
  • [MeSH-minor] Adolescent. Adult. Aged. Bone Marrow / pathology. Chromosome Aberrations. Disease-Free Survival. Erythropoiesis / genetics. Humans. Middle Aged. Neoplasms, Second Primary / genetics. Neoplasms, Second Primary / metabolism. Neoplasms, Second Primary / mortality. Neoplasms, Second Primary / pathology. Prognosis. Survival Analysis. Young Adult

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  • (PMID = 19097174.001).
  • [ISSN] 1096-8652
  • [Journal-full-title] American journal of hematology
  • [ISO-abbreviation] Am. J. Hematol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / GATA1 Transcription Factor; 0 / GATA1 protein, human; 0 / GATA2 Transcription Factor; 0 / GATA2 protein, human; 0 / Kruppel-Like Transcription Factors; 0 / Neoplasm Proteins; 0 / Receptors, Thrombopoietin; 0 / erythroid Kruppel-like factor; 143641-95-6 / MPL protein, human
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67. Minke KS, Staib P, Puetter A, Gehrke I, Gandhirajan RK, Schlösser A, Schmitt EK, Hallek M, Kreuzer KA: Small molecule inhibitors of WNT signaling effectively induce apoptosis in acute myeloid leukemia cells. Eur J Haematol; 2009 Mar;82(3):165-75
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  • [Title] Small molecule inhibitors of WNT signaling effectively induce apoptosis in acute myeloid leukemia cells.
  • In a significant proportion of acute myeloid leukemia (AML) cases the canonical WNT pathway is upregulated and targeting the WNT/LEF1 signaling cascade in AML may be a promising approach to develop new treatments for this entity.
  • Recently two compounds (CGP049090 and PFK115-584) have been identified, which specifically inhibit complexation of beta-catenin (CTNNB1) and lymphoid enhancer-binding factor 1 (LEF1) leading to transcriptional inactivation of LEF1 in colon carcinoma cell lines.
  • [MeSH-major] Apoptosis / drug effects. Leukemia, Myeloid, Acute / metabolism. Leukemia, Myeloid, Acute / pathology. Perylene / analogs & derivatives. Signal Transduction / drug effects. Wnt Proteins / antagonists & inhibitors
  • [MeSH-minor] Adenosine Triphosphate / metabolism. Adult. Aged. Aged, 80 and over. Female. Humans. Lymphoid Enhancer-Binding Factor 1 / metabolism. Male. Middle Aged. Molecular Structure. Tumor Cells, Cultured. beta Catenin / metabolism

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  • (PMID = 19067737.001).
  • [ISSN] 1600-0609
  • [Journal-full-title] European journal of haematology
  • [ISO-abbreviation] Eur. J. Haematol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / CGP049090; 0 / CTNNB1 protein, human; 0 / Lymphoid Enhancer-Binding Factor 1; 0 / PKF115-584; 0 / Wnt Proteins; 0 / beta Catenin; 5QD5427UN7 / Perylene; 8L70Q75FXE / Adenosine Triphosphate
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68. Hsu FC, Lin PC, Chi CY, Ho MW, Ho CM, Wang JH: Prognostic factors for patients with culture-positive Candida infection undergoing abdominal surgery. J Microbiol Immunol Infect; 2009 Oct;42(5):378-84
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  • METHODS: From 2003 through 2006, all adult patients with positive candidal culture from abdominal specimens (peritoneal fluid obtained during laparotomy or drain effluent, abscess, or bile) at China Medical University Hospital, Taichung, Taiwan, were included in this retrospective study.
  • The major prognostic factors were number of surgical interventions, Gram-negative bacteremia, high Acute Physiology And Chronic Health Evaluation (APACHE) II score, corticosteroid use, and subsequent candidal infection (p < 0.05).
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Hospitals. Humans. Male. Middle Aged. Prognosis. Taiwan

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  • (PMID = 20182666.001).
  • [ISSN] 1995-9133
  • [Journal-full-title] Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
  • [ISO-abbreviation] J Microbiol Immunol Infect
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
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69. Kasper B: Standards and novel therapeutic options in the treatment of patients with soft tissue sarcoma. Rev Recent Clin Trials; 2007 Sep;2(3):206-11
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  • They account for less than 1% of all adult malignancies.


70. Boyer LA, Plath K, Zeitlinger J, Brambrink T, Medeiros LA, Lee TI, Levine SS, Wernig M, Tajonar A, Ray MK, Bell GW, Otte AP, Vidal M, Gifford DK, Young RA, Jaenisch R: Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature; 2006 May 18;441(7091):349-53
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  • The mechanisms by which embryonic stem (ES) cells self-renew while maintaining the ability to differentiate into virtually all adult cell types are not well understood.


71. Patteril M, Stafford-Smith M, Toffaletti JG, Bute BP, Milano CA, Welsby IJ: Changing systems for measuring activated clotting times: impact on the clinical practice of heparin anticoagulation during cardiac surgery. Clin Chim Acta; 2005 Jun;356(1-2):218-24
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  • METHODS: We compared the intraoperative heparin doses required for all adult cardiac surgery patients (n=1240) and postoperative bleeding for a subset of primary aortocoronary bypass (CABG) surgery procedures (n=285) from cohorts before and after the change in ACT systems.
  • [MeSH-minor] Adult. Aged. Cardiopulmonary Bypass. Cohort Studies. Female. Humans. Male. Middle Aged. Retrospective Studies

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  • (PMID = 15936321.001).
  • [ISSN] 0009-8981
  • [Journal-full-title] Clinica chimica acta; international journal of clinical chemistry
  • [ISO-abbreviation] Clin. Chim. Acta
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Anticoagulants; 9005-49-6 / Heparin
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72. Fernández-Cotarelo MJ, López-Medrano F, San Juan R, Díaz-Pedroche C, Lizasoain M, Chaves F, Aguado JM: Protean manifestations of pleural empyema caused by Streptococcus pneumoniae in adults. Eur J Intern Med; 2007 Mar;18(2):141-5
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  • We included all adult patients with pleural empyema caused by S. pneumoniae diagnosed from 1998 to 2004.
  • All pleural fluids had a high white blood cell count, either with polymorphonuclear or lymphocytic predominance.
  • Clinical manifestations are variable and pleural fluid can be a lymphocytic exudate.

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  • (PMID = 17338967.001).
  • [ISSN] 0953-6205
  • [Journal-full-title] European journal of internal medicine
  • [ISO-abbreviation] Eur. J. Intern. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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73. Giblin L, Hollander M, Little D, Hickey D, Donohoe J, Walshe JJ, Dorman A, O'Kelly P, Conlon PJ: Renal transplantation in the elderly--the Irish experience. Ir J Med Sci; 2005 Apr-Jun;174(2):9-13
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  • METHODS: A retrospective review of all adult renal transplants performed at Beaumont Hospital between the years 1986-2001 was carried out.

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  • (PMID = 16094906.001).
  • [ISSN] 0021-1265
  • [Journal-full-title] Irish journal of medical science
  • [ISO-abbreviation] Ir J Med Sci
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Ireland
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74. Thomas DA, Sarris AH, Cortes J, Faderl S, O'Brien S, Giles FJ, Garcia-Manero G, Rodriguez MA, Cabanillas F, Kantarjian H: Phase II study of sphingosomal vincristine in patients with recurrent or refractory adult acute lymphocytic leukemia. Cancer; 2006 Jan 1;106(1):120-7
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  • [Title] Phase II study of sphingosomal vincristine in patients with recurrent or refractory adult acute lymphocytic leukemia.
  • BACKGROUND: Outcomes with salvage therapy for patients with recurrent or refractory acute lymphocytic leukemia (ALL) are poor, with complete response (CR) rates reported to be 20-30% and a median survival ranging from 2-6 months.
  • Five patients (36%) had transient reductions in bone marrow leukemia infiltrate with subsequent regrowth of the leukemia between SV infusions.
  • [MeSH-major] Antineoplastic Agents, Phytogenic / therapeutic use. Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy. Salvage Therapy. Vincristine / therapeutic use
  • [MeSH-minor] Adolescent. Adult. Aged. Drug Administration Schedule. Drug Resistance, Neoplasm. Humans. Liposomes. Middle Aged. Recurrence. Sphingomyelins

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  • [Copyright] Copyright 2005 American Cancer Society.
  • [ErratumIn] Cancer. 2006 Apr 1;106(7):1641
  • (PMID = 16331634.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; 0 / Liposomes; 0 / Sphingomyelins; 5J49Q6B70F / Vincristine
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75. Barion LA, Tsuneto LT, Testa GV, Lieber SR, Persoli LB, Marques SB, Vigorito AC, Aranha FJ, Eid KA, Oliveira GB, Miranda EC, Souza CA, Visentainer JE: [Association between HLA and leukemia in a mixed Brazilian population]. Rev Assoc Med Bras (1992); 2007 May-Jun;53(3):252-6
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  • [Title] [Association between HLA and leukemia in a mixed Brazilian population].
  • OBJECTIVE: The main purpose of this study was to investigate the class I HLA antigens and class II HLA allele frequencies in 164 patients with leukemia: 35 patients with ALL (acute lymphoid leukemia), 50 with AML (acute myeloid leukemia) and 78 with CML (chronic myeloid leukemia).
  • CONCLUSION: Our results suggest that variants of HLA confer susceptibility to the same forms of leukemia, and could provide new tools for the investigation of genetics and etiology of this disease.
  • [MeSH-major] Gene Frequency. HLA-A Antigens / analysis. HLA-B Antigens / analysis. Leukemia / genetics
  • [MeSH-minor] Adolescent. Adult. Brazil / epidemiology. Child. Child, Preschool. Female. Genetic Predisposition to Disease. Haplotypes. Humans. Infant. Karyotyping. Leukemia, Myelogenous, Chronic, BCR-ABL Positive / genetics. Leukemia, Myeloid, Acute / genetics. Male. Middle Aged. Phenotype. Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics

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  • (PMID = 17665074.001).
  • [ISSN] 0104-4230
  • [Journal-full-title] Revista da Associação Médica Brasileira (1992)
  • [ISO-abbreviation] Rev Assoc Med Bras (1992)
  • [Language] por
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Brazil
  • [Chemical-registry-number] 0 / HLA-A Antigens; 0 / HLA-B Antigens
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76. Zelezníková T, Babusíková O: The impact of cell heterogeneity and immunophenotypic changes on monitoring minimal residual disease in acute myeloid leukemia. Neoplasma; 2006;53(6):500-6
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  • [Title] The impact of cell heterogeneity and immunophenotypic changes on monitoring minimal residual disease in acute myeloid leukemia.
  • Monitoring of minimal residual disease (MRD) becomes increasingly important for the more accurate stratification of the therapy in acute leukemia.
  • The purpose of this study was to characterize in detail the phenotypes of heterogeneous population in various AML subtypes and to identify the leukemia associated aberrant phenotype (LAP) in individual patients with AML for precise investigation of MRD.
  • Although AML cells often have light scattering properties similar to those of normal (myeloid and B-lymphoid precursors, basophiles etc.) in a fraction of cases we found also very useful the location on CD45/SSC dot plots for MRD discrimination.
  • [MeSH-major] Immunophenotyping. Leukemia, Myeloid / diagnosis. Neoplasm, Residual / diagnosis
  • [MeSH-minor] Acute Disease. Adolescent. Adult. Aged. Aged, 80 and over. Antigens, CD45 / metabolism. Blast Crisis / diagnosis. Blast Crisis / immunology. Bone Marrow / immunology. Child. Child, Preschool. Female. Flow Cytometry. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / immunology. Phenotype. Prognosis

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  • (PMID = 17167719.001).
  • [ISSN] 0028-2685
  • [Journal-full-title] Neoplasma
  • [ISO-abbreviation] Neoplasma
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Slovakia
  • [Chemical-registry-number] EC 3.1.3.48 / Antigens, CD45
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77. Clappier E, Cuccuini W, Cayuela JM, Vecchione D, Baruchel A, Dombret H, Sigaux F, Soulier J: Cyclin D2 dysregulation by chromosomal translocations to TCR loci in T-cell acute lymphoblastic leukemias. Leukemia; 2006 Jan;20(1):82-6
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  • [Title] Cyclin D2 dysregulation by chromosomal translocations to TCR loci in T-cell acute lymphoblastic leukemias.
  • While the cyclin D1 and D3 genes (CCND1 and CCND3) are recurrently involved in genomic rearrangements, especially in B-cell lymphoid neoplasias, no clear involvement of the cyclin D2 gene (CCND2) has been reported to date.
  • Here, we identified chromosomal translocations targeting the CCND2 locus at 12p13, and the T-cell receptor beta (TCRB) or the TCRA/D loci in T-cell acute lymphoblastic leukemias (T-ALLs).
  • [MeSH-major] Chromosomes, Human, Pair 12 / genetics. Cyclins / biosynthesis. Cyclins / genetics. Leukemia-Lymphoma, Adult T-Cell / genetics. Receptors, Antigen, T-Cell / genetics. Translocation, Genetic
  • [MeSH-minor] Adult. Cell Separation. Child. Cyclin D2. Cytogenetic Analysis. DNA Mutational Analysis. Gene Rearrangement. Humans

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  • (PMID = 16270038.001).
  • [ISSN] 0887-6924
  • [Journal-full-title] Leukemia
  • [ISO-abbreviation] Leukemia
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / CCND2 protein, human; 0 / Cyclin D2; 0 / Cyclins; 0 / Receptors, Antigen, T-Cell
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78. Hu XX, Gong SL, Song XM, Chen L, Qiu HY, Gao L, Wang JM: [Report of a case of hybrid acute leukemia with t (12; 22) and literature review]. Zhonghua Xue Ye Xue Za Zhi; 2006 May;27(5):331-4
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  • [Title] [Report of a case of hybrid acute leukemia with t (12; 22) and literature review].
  • OBJECTIVE: To report a hybrid acute leukemia (HAL) patient with t (12;.
  • Leukemia surface markers were detected by anti-biotin-biotin complex and monoclonal antibodies.
  • Lymphoid and myeloid markers were positive on the leukemia cells.
  • 22) translocation is a rare chromosome abnormality in leukemia.
  • This translocation as a cytogenetic marker for poor-prognosis in leukemia needs to be further studied.
  • [MeSH-major] Chromosomes, Human, Pair 12 / genetics. Chromosomes, Human, Pair 22 / genetics. Leukemia, Biphenotypic, Acute / genetics. Translocation, Genetic
  • [MeSH-minor] Adult. Chromosome Banding. Female. Humans. In Situ Hybridization, Fluorescence. Karyotyping

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  • (PMID = 16875585.001).
  • [ISSN] 0253-2727
  • [Journal-full-title] Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi
  • [ISO-abbreviation] Zhonghua Xue Ye Xue Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] China
  • [Number-of-references] 20
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79. El-Sissy A, El-Mashari M, Bassuni W, El-Swaayed A: Molecular detection of BCR/ABL fusion gene in Saudi acute lymphoblastic leukemia patients. J Egypt Natl Canc Inst; 2006 Jun;18(2):109-16
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  • [Title] Molecular detection of BCR/ABL fusion gene in Saudi acute lymphoblastic leukemia patients.
  • A fraction of acute lymphoblastic leukemia (ALL) cases carry the translocation t(9;22) (q34;q11.2) which juxtaposes the ABL proto-oncogene to the BCR gene generating a chimeric gene, BCR/ABL.
  • This aberration is more frequent in adult ALL (20%-40%) than in pediatric ALL (<5%), and predicts poor clinical outcome.
  • PATIENTS AND METHODS: Twenty newly diagnosed ALL patients, 16 adult and 4 paediatric cases, were included in the study, 11 cases (55%) were of precursor B phenotype, 8 cases (40%) belonged to T lineage, while one case was biphenotypic expressing mainly precursor B cell markers tether with CD13, CD33, CD117, Detection of BCR/ABL fusion gene was done using interphase FISH technique and was confirmed molecularly using the RT-PCR technique.
  • [MeSH-major] Fusion Proteins, bcr-abl / genetics. Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnosis

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  • (PMID = 17496935.001).
  • [ISSN] 1110-0362
  • [Journal-full-title] Journal of the Egyptian National Cancer Institute
  • [ISO-abbreviation] J Egypt Natl Canc Inst
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
  • [Chemical-registry-number] 0 / Antigens, Differentiation, B-Lymphocyte; 0 / RNA, Messenger; EC 2.7.10.2 / Fusion Proteins, bcr-abl
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80. Gooneratne LV, Wijeratne MD, Gunasekara HD, Tudawe MN: Acute leukaemia of ambiguous lineage--a diagnostic dilemma. Ceylon Med J; 2009 Jun;54(2):51-3
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  • [Title] Acute leukaemia of ambiguous lineage--a diagnostic dilemma.
  • Acute leukaemia of ambiguous lineage (ALAL) is a rare form of leukaemia in which morphologic, cytochemical and immuno-phenotypic features of the proliferating blasts lack sufficient evidence to classify them as myeloid or lymphoid in origin or have characteristics of both myeloid and lymphoid cells.
  • We report a 22-year-old man presenting with clinical features of an acute lymphoblastic leukaemia but blasts in his blood and bone marrow with morphological features of myeloblasts.
  • His immuno-phenotyping by flowcytometry showed antigens specific for both myeloid and B-lymphoid lineages.
  • We highlight the importance of correlating clinical features with cellular morphology when diagnosing acute leukaemias, especially when facilities for flowcytometry are not routinely available.
  • [MeSH-major] Leukemia / diagnosis
  • [MeSH-minor] Acute Disease. Adult. Fatal Outcome. Humans. Male

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  • (PMID = 19670549.001).
  • [ISSN] 0009-0875
  • [Journal-full-title] The Ceylon medical journal
  • [ISO-abbreviation] Ceylon Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Sri Lanka
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81. Mangurian C, Miller GA, Jackson CT, Li H, Essock SM, Sederer LI: State mental health policy: Physical health screening in state mental health clinics: the New York health indicators initiative. Psychiatr Serv; 2010 Apr;61(4):346-8
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  • The New York State Office of Mental Health recently mandated that all adult outpatient clinics regularly monitor three health indicators--body mass index, blood pressure, and smoking status.
  • [MeSH-minor] Adult. Health Plan Implementation / legislation & jurisprudence. Health Plan Implementation / organization & administration. Health Promotion / legislation & jurisprudence. Health Promotion / organization & administration. Humans. Inservice Training. Medical Records Systems, Computerized / legislation & jurisprudence. Medical Records Systems, Computerized / organization & administration. New York


82. Chitre MM, Hayes W: 3-year results of a member and physician intervention to reduce risk associated with glucocorticoid-induced osteoporosis in a health plan. J Manag Care Pharm; 2008 Apr;14(3):281-90
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  • METHODS: Pharmacy claims were analyzed for a 4-month period in each of 3 years, for claims with dates of service from April 1 through July 30, 2003, May 1 through August 31, 2004, and February 4 through May 5, 2005, to identify all adult members of a health plan of approximately 1.3 million members who received an oral glucocorticoid (e.g., prednisone, dexamethasone) for at least 90 of 120 days (chronic use) and did not receive a medication for osteoporosis prevention (e.g., risedronate, ibandronate, etidronate, raloxifene, alendronate, calcitonin) during the same 120-day time period.
  • [MeSH-minor] Administration, Oral. Adult. Calcitonin / therapeutic use. Databases, Factual. Diphosphonates / therapeutic use. Education, Medical, Continuing / methods. Female. Follow-Up Studies. Humans. Male. Managed Care Programs. Patient Education as Topic / methods. Physicians / standards. Prevalence. Risk Factors. United States

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  • (PMID = 18439050.001).
  • [ISSN] 1083-4087
  • [Journal-full-title] Journal of managed care pharmacy : JMCP
  • [ISO-abbreviation] J Manag Care Pharm
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Bone Density Conservation Agents; 0 / Diphosphonates; 0 / Glucocorticoids; 9007-12-9 / Calcitonin
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83. Piccaluga PP, Martinelli G, Rondoni M, Visani G, Baccarani M: Advances and potential treatment for Philadelphia chromosome-positive adult acute lymphoid leukaemia. Expert Opin Biol Ther; 2006 Oct;6(10):1011-22
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  • [Title] Advances and potential treatment for Philadelphia chromosome-positive adult acute lymphoid leukaemia.
  • Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukaemia (ALL) is the most common subtype of ALL in adults.
  • Conventional chemotherapy-based approaches that are effective in other precursor B cell ALL cases have a poor chances of cure in patients with a Ph+ diagnosis.
  • [MeSH-major] Leukemia, Myelogenous, Chronic, BCR-ABL Positive / genetics. Leukemia, Myelogenous, Chronic, BCR-ABL Positive / therapy. Philadelphia Chromosome
  • [MeSH-minor] Adult. Animals. Humans. Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy. Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics. Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy. Randomized Controlled Trials as Topic / trends. Stem Cell Transplantation / methods. Stem Cell Transplantation / trends

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  • (PMID = 16989583.001).
  • [ISSN] 1744-7682
  • [Journal-full-title] Expert opinion on biological therapy
  • [ISO-abbreviation] Expert Opin Biol Ther
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
  • [Number-of-references] 61
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84. Vega F, Medeiros LJ, Davuluri R, Cromwell CC, Alkan S, Abruzzo LV: t(8;13)-positive bilineal lymphomas: report of 6 cases. Am J Surg Pathol; 2008 Jan;32(1):14-20
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  • The 8p11 myeloproliferative syndrome (EMS) is a rare hematologic malignancy characterized by myeloid hyperplasia, eosinophilia, and precursor lymphoblastic lymphoma, associated with balanced translocations involving chromosome 8p11, most commonly t(8;13)(p11;q12).
  • Approximately 75% of EMS patients present with or develop precursor T-cell lymphoblastic lymphoma, and most subsequently develop acute myeloid leukemia.
  • In all cases, the latter component tended to surround residual lymphoid follicles and/or blood vessels.
  • [MeSH-minor] Adolescent. Adult. Antigens, CD / metabolism. Cell Lineage. Child. Female. Granulocyte Precursor Cells / metabolism. Granulocyte Precursor Cells / pathology. Humans. Immunohistochemistry. Immunophenotyping. Lymphocytes / metabolism. Lymphocytes / pathology. Male. Reverse Transcriptase Polymerase Chain Reaction. Translocation, Genetic

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  • (PMID = 18162765.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD
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85. Lehmann R, Beekley A, Casey L, Salim A, Martin M: The impact of advanced age on trauma triage decisions and outcomes: a statewide analysis. Am J Surg; 2009 May;197(5):571-4; discussion 574-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: The study population was all adult patients in the Washington State Trauma Registry from 2000 to 2004.
  • [MeSH-minor] Adult. Age Factors. Aged. Decision Making. Female. Geriatric Assessment. Healthcare Disparities / statistics & numerical data. Humans. Logistic Models. Male. Middle Aged. Multivariate Analysis. Retrospective Studies

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  • (PMID = 19393350.001).
  • [ISSN] 1879-1883
  • [Journal-full-title] American journal of surgery
  • [ISO-abbreviation] Am. J. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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86. Lin EE, Rodgers GP, Gladwin MT: Hemolytic anemia-associated pulmonary hypertension in sickle cell disease. Curr Hematol Rep; 2005 Mar;4(2):117-25
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  • Pulmonary hypertension is one of the leading causes of death in adult sickle cell patients, with a prevalence of 20% to 40%.
  • Therefore, all adult patients with sickle cell disease should be screened with transthoracic Doppler echocardiogram and the tricuspid regurgitant jet (TRJ) velocity measured to estimate pulmonary artery pressures.
  • [MeSH-minor] Adult. Cardiac Output. Hemolysis. Humans. Multicenter Studies as Topic. Prevalence. Tricuspid Valve Insufficiency / ultrasonography


87. Albitar M, Potts SJ, Giles FJ, O'Brien S, Keating M, Thomas D, Clarke C, Jilani I, Aguilar C, Estey E, Kantarjian H: Proteomic-based prediction of clinical behavior in adult acute lymphoblastic leukemia. Cancer; 2006 Apr 1;106(7):1587-94
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  • [Title] Proteomic-based prediction of clinical behavior in adult acute lymphoblastic leukemia.
  • BACKGROUND: Response in adult acute lymphoblastic leukemia (ALL) can be achieved in a majority of patients.
  • However, unlike pediatric ALL, recurrence is common in adult ALL, and the ability to predict at an early stage which patients are most likely to experience recurrence may help in devising new therapeutic approaches to prevent recurrence.
  • [MeSH-major] Decision Trees. Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics. Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology. Proteomics
  • [MeSH-minor] Adolescent. Adult. Age Factors. Aged. Child, Preschool. Female. Humans. Male. Middle Aged. Predictive Value of Tests. Prognosis. Protein Array Analysis. Recurrence

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  • [Copyright] Copyright 2006 American Cancer Society.
  • (PMID = 16518825.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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88. Gill J, Bunnapradist S, Danovitch GM, Gjertson D, Gill JS, Cecka M: Outcomes of kidney transplantation from older living donors to older recipients. Am J Kidney Dis; 2008 Sep;52(3):541-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • SETTING & PARTICIPANTS: All adult kidney-only transplantations performed in recipients 60 years and older from 1996 to 2005 were included.
  • [MeSH-minor] Acute Disease. Aged. Cohort Studies. Delayed Graft Function / epidemiology. Female. Graft Rejection / epidemiology. Graft Survival. Humans. Incidence. Kidney / physiopathology. Male. Middle Aged. Postoperative Complications / epidemiology. Postoperative Period. Proportional Hazards Models. Renal Insufficiency / epidemiology. Survival Analysis. Time Factors. Transplantation, Homologous. Treatment Outcome


89. Savard JF, Faisy C, Lerolle N, Guerot E, Diehl JL, Fagon JY: Validation of a predictive method for an accurate assessment of resting energy expenditure in medical mechanically ventilated patients. Crit Care Med; 2008 Apr;36(4):1175-83
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  • PATIENTS: All adult patients intubated >24 hrs were assessed for eligibility.

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  • [CommentIn] Crit Care Med. 2008 Apr;36(4):1375-6 [18379277.001]
  • (PMID = 18379244.001).
  • [ISSN] 1530-0293
  • [Journal-full-title] Critical care medicine
  • [ISO-abbreviation] Crit. Care Med.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
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90. Higuera F, Rosenthal VD, Duarte P, Ruiz J, Franco G, Safdar N: The effect of process control on the incidence of central venous catheter-associated bloodstream infections and mortality in intensive care units in Mexico. Crit Care Med; 2005 Sep;33(9):2022-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • SETTING: Two level III adult ICUs in one public university hospital in Mexico: one medical surgical ICU and one neurosurgical ICU.
  • POPULATION STUDY: All adult patients admitted to study units who had a central venous catheter (CVC) in place for at least 24 hrs.
  • [MeSH-minor] Adult. Cross Infection / epidemiology. Cross Infection / mortality. Humans. Mexico / epidemiology. Prospective Studies

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  • [CommentIn] Crit Care Med. 2005 Sep;33(9):2133-4 [16148500.001]
  • (PMID = 16148475.001).
  • [ISSN] 0090-3493
  • [Journal-full-title] Critical care medicine
  • [ISO-abbreviation] Crit. Care Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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91. Reed DN Jr, Wolf B, Barber KR, Kotlowski R, Montanez M, Saxe A, Coffey DC, Pollard M, Fitzgerald HE, Richardson JD: The stages of change questionnaire as a predictor of trauma patients most likely to decrease alcohol use. J Am Coll Surg; 2005 Feb;200(2):179-85
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The current study extends such findings by examining whether stage of readiness to change among all adult trauma activations admitted to the emergency department for 24 hours or more can be used to predict a change in behavior at followup.
  • [MeSH-minor] Adult. Attitude to Health. Ethanol / blood. Female. Humans. Injury Severity Score. Male. Patient Compliance


92. Park YH, Kim WS, Kang HJ, Na II, Ryoo BY, Yang SH, Lee SS, Uhm JE, Kim K, Jung CW, Park K, Ko YH: Gastric Burkitt lymphoma is a distinct subtype that has superior outcomes to other types of Burkitt lymphoma/leukemia. Ann Hematol; 2006 May;85(5):285-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gastric Burkitt lymphoma is a distinct subtype that has superior outcomes to other types of Burkitt lymphoma/leukemia.
  • Burkitt lymphoma/leukemia (BL) is a highly aggressive non-Hodgkin's lymphoma (NHL) often presenting in extranodal sites or as an acute leukemia.
  • Because of the shared molecular and genetic features, the World Health Organization classification of lymphoid diseases recognizes the lymphomatous and leukemic phases of BL as a single entity: a mature B cell neoplasm, subtype Burkitt lymphoma/Burkitt cell leukemia.
  • [MeSH-minor] Adolescent. Adult. Aged. Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Antineoplastic Combined Chemotherapy Protocols / adverse effects. Child. Disease-Free Survival. Female. Follow-Up Studies. Humans. Male. Middle Aged. Remission Induction. Retrospective Studies. Survival Rate

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  • (PMID = 16518604.001).
  • [ISSN] 0939-5555
  • [Journal-full-title] Annals of hematology
  • [ISO-abbreviation] Ann. Hematol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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93. Mantadakis E, Danilatou V, Stiakaki E, Paterakis G, Papadhimitriou S, Kalmanti M: T-cell acute lymphoblastic leukemia relapsing as acute myelogenous leukemia. Pediatr Blood Cancer; 2007 Mar;48(3):354-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] T-cell acute lymphoblastic leukemia relapsing as acute myelogenous leukemia.
  • We present the unusual case of a 16-year-old girl with T-cell acute lymphoblastic leukemia (ALL) with an early thymocyte immunophenotype without myeloid markers, who after 13 months of complete hematological remission relapsed as acute myelogenous leukemia (AML) with minimal differentiation and died of her disease.
  • [MeSH-major] Antigens, Differentiation, T-Lymphocyte / analysis. Antigens, Neoplasm / analysis. Leukemia, Myeloid / pathology. Leukemia-Lymphoma, Adult T-Cell / pathology. Neoplastic Stem Cells / pathology. T-Lymphocyte Subsets / pathology
  • [MeSH-minor] 6-Mercaptopurine / administration & dosage. Acute Disease. Adolescent. Antigens, CD7 / analysis. Antineoplastic Combined Chemotherapy Protocols / adverse effects. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Asparaginase / administration & dosage. Bone Marrow / pathology. Cell Differentiation. Cell Lineage. Core Binding Factor Alpha 2 Subunit / genetics. Cyclophosphamide / administration & dosage. Cytarabine / administration & dosage. Daunorubicin / administration & dosage. Dexamethasone / administration & dosage. Diagnosis, Differential. Doxorubicin / administration & dosage. Etoposide / administration & dosage. Etoposide / adverse effects. Fatal Outcome. Female. Gene Dosage. Histone-Lysine N-Methyltransferase. Humans. Immunophenotyping. Karyotyping. Methotrexate / administration & dosage. Myeloid-Lymphoid Leukemia Protein / genetics. Neoplasms, Second Primary / diagnosis. Proto-Oncogenes. Recurrence. Vincristine / administration & dosage

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  • Hazardous Substances Data Bank. CYTARABINE .
  • Hazardous Substances Data Bank. DAUNORUBICIN .
  • Hazardous Substances Data Bank. DOXORUBICIN .
  • Hazardous Substances Data Bank. ETOPOSIDE .
  • Hazardous Substances Data Bank. DEXAMETHASONE .
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  • Hazardous Substances Data Bank. MERCAPTOPURINE .
  • Hazardous Substances Data Bank. VINCRISTINE .
  • Hazardous Substances Data Bank. METHOTREXATE .
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  • [Copyright] (c) 2006 Wiley-Liss, Inc.
  • (PMID = 16206214.001).
  • [ISSN] 1545-5009
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD7; 0 / Antigens, Differentiation, T-Lymphocyte; 0 / Antigens, Neoplasm; 0 / Core Binding Factor Alpha 2 Subunit; 0 / MLL protein, human; 0 / RUNX1 protein, human; 04079A1RDZ / Cytarabine; 149025-06-9 / Myeloid-Lymphoid Leukemia Protein; 5J49Q6B70F / Vincristine; 6PLQ3CP4P3 / Etoposide; 7S5I7G3JQL / Dexamethasone; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; E7WED276I5 / 6-Mercaptopurine; EC 2.1.1.43 / Histone-Lysine N-Methyltransferase; EC 3.5.1.1 / Asparaginase; YL5FZ2Y5U1 / Methotrexate; ZS7284E0ZP / Daunorubicin
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94. Juliusson G, Karlsson K, Hallböök H: Population-based analyses in adult acute lymphoblastic leukemia. Blood; 2010 Aug 12;116(6):1011; author reply 1012
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Population-based analyses in adult acute lymphoblastic leukemia.
  • [MeSH-major] Precursor Cell Lymphoblastic Leukemia-Lymphoma / mortality. Registries / statistics & numerical data

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  • [CommentOn] Blood. 2010 Jan 14;115(2):206-14 [19897583.001]
  • (PMID = 20705768.001).
  • [ISSN] 1528-0020
  • [Journal-full-title] Blood
  • [ISO-abbreviation] Blood
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] United States
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95. Choi MY, Raina A, Vander Meer RK: PBAN/pyrokinin peptides in the central nervous system of the fire ant, Solenopsis invicta. Cell Tissue Res; 2009 Feb;335(2):431-9
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  • Immunoreactive material is detectable in at least three groups of neurons in the subesophageal ganglion and corpora cardiaca of all adult sexual forms.
  • In support of our immunocytochemical results, significant pheromonotropic activity is found in fire ant brain-subesophageal ganglion extracts from all adult fire ant forms (queens, female and male alates, and workers) when extracts are injected into decapitated females of Helicoverpa zea.

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  • (PMID = 19002499.001).
  • [ISSN] 1432-0878
  • [Journal-full-title] Cell and tissue research
  • [ISO-abbreviation] Cell Tissue Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Neuropeptides; 0 / Pheromones; 0 / pheromone biosynthesis activating neuropeptide, Helicoverpa zea; 0 / pyrokinin
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96. Franz T, Hasler RM, Benneker L, Zimmermann H, Siebenrock KA, Exadaktylos AK: Severe spinal injuries in alpine skiing and snowboarding: a 6-year review of a tertiary trauma centre for the Bernese Alps ski resorts, Switzerland. Br J Sports Med; 2008 Jan;42(1):55-8
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  • STUDY DESIGN: A six-year review of all adult patients with severe spinal injuries sustained from alpine skiing or snowboarding.
  • PATIENTS AND METHODS: All adult patients (over 16 years of age) admitted to a tertiary trauma centre from 1 July 2000, through 30 June 2006, were reviewed using a computerised database.
  • [MeSH-minor] Accident Prevention / methods. Adolescent. Adult. Age Factors. Aged. Female. Humans. Injury Severity Score. Male. Middle Aged. Protective Devices. Retrospective Studies. Risk Factors. Sex Factors. Switzerland / epidemiology

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  • (PMID = 17562746.001).
  • [ISSN] 1473-0480
  • [Journal-full-title] British journal of sports medicine
  • [ISO-abbreviation] Br J Sports Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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97. Simpson DG: Dermal templates and the wound-healing paradigm: the promise of tissue regeneration. Expert Rev Med Devices; 2006 Jul;3(4):471-84
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  • Unfortunately, in the adult, all too often, wound healing occurs at the other extreme of the continuum and the dermis is reconstituted as scar tissue.

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  • (PMID = 16866644.001).
  • [ISSN] 1743-4440
  • [Journal-full-title] Expert review of medical devices
  • [ISO-abbreviation] Expert Rev Med Devices
  • [Language] eng
  • [Grant] United States / NIBIB NIH HHS / EB / R01 EB003087
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Review
  • [Publication-country] England
  • [Number-of-references] 122
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98. Vadillo-Carstensen L, Luna-Pizarro D, Cruz-Alvarez D, Hernández-Cuevas V: [Pre- and postoperative functional status of patients subjected to anterior cruciate ligament reconstruction associated with knee dislocation]. Acta Ortop Mex; 2010 Nov-Dec;24(6):400-3
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  • MATERIAL AND METHODS: An observational, prospective, cross-sectional study was conducted including all adult patients with a diagnosis of cruciate ligament injury resulting from knee dislocation who were surgically treated from January 2006 to December 2007.
  • [MeSH-minor] Adolescent. Adult. Cross-Sectional Studies. Female. Humans. Male. Middle Aged. Orthopedic Procedures. Prospective Studies. Recovery of Function. Young Adult

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  • (PMID = 21400763.001).
  • [ISSN] 2306-4102
  • [Journal-full-title] Acta ortopédica mexicana
  • [ISO-abbreviation] Acta Ortop Mex
  • [Language] spa
  • [Publication-type] Controlled Clinical Trial; English Abstract; Journal Article
  • [Publication-country] Mexico
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99. Tewari S, Kathuria A, Meier-Kriesche HU, Lansang MC: Association between admission hyperglycemia and length of stay after renal transplantation. Endocr Pract; 2010 Sep-Oct;16(5):805-9
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  • METHODS: We conducted a retrospective analysis of all adult patients who underwent renal transplant at an academic center during 2006.
  • [MeSH-minor] Adolescent. Adult. Aged. Blood Glucose / analysis. Blood Glucose / metabolism. Female. Humans. Male. Middle Aged. Osmolar Concentration. Retrospective Studies. Young Adult

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  • (PMID = 20439248.001).
  • [ISSN] 1934-2403
  • [Journal-full-title] Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
  • [ISO-abbreviation] Endocr Pract
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Blood Glucose
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100. Marlow RA, Kegowicz CL, Starkey KN: Prevalence of depression symptoms in outpatients with a complaint of headache. J Am Board Fam Med; 2009 Nov-Dec;22(6):633-7
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  • METHODS: Adult, English-speaking patients who presented to a primary care office with a chief complaint of headache were matched to adult patients of the same age and sex who presented with problems other than headache.
  • CONCLUSIONS: Almost one-third of adult patients who present to a primary care office with a complaint of headache report moderate symptoms of depression when screened compared with approximately 10% of patients presenting with a complaint other than headache.
  • Given such a high prevalence of these symptoms, primary care physicians should screen all adult patients who present with headache for depression.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Arizona / epidemiology. Case-Control Studies. Comorbidity. Female. Humans. Male. Mass Screening. Middle Aged. Prevalence. Surveys and Questionnaires. Young Adult

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  • [CommentIn] J Am Board Fam Med. 2009 Nov-Dec;22(6):602-3 [19897686.001]
  • (PMID = 19897691.001).
  • [ISSN] 1557-2625
  • [Journal-full-title] Journal of the American Board of Family Medicine : JABFM
  • [ISO-abbreviation] J Am Board Fam Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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