[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 100 of about 342
1. Beltramini GA, Baj A, Moneghini L, Poli T, Combi VA, Giannì AB: Microcystic adnexal carcinoma of the centrofacial region: a case report. Acta Otorhinolaryngol Ital; 2010 Aug;30(4):213
Genetic Alliance. consumer health - Microcystic adnexal carcinoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Microcystic adnexal carcinoma of the centrofacial region: a case report.
  • Microcystic adnexal carcinoma is a rare, locally aggressive neoplasm with both eccrine and follicular differentiation and a high probability of perineural invasion of the centrofacial region.
  • Given the histopathological features of this tumour, early diagnosis is essential for adequate management.
  • This report refers to a case of microcystic adnexal carcinoma of the nasogenial region, with infiltration of the deep planes extending to the anterior wall of the maxillary sinus.
  • [MeSH-major] Carcinoma. Facial Neoplasms

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Pathologica. 2000 Aug;92(4):225-35 [11029882.001]
  • [Cites] Cancer. 1982 Aug 1;50(3):566-72 [7093897.001]
  • [Cites] Int Ophthalmol Clin. 1989 Winter;29(4):237-46 [2687187.001]
  • [Cites] Clin Exp Dermatol. 1990 May;15(3):222-4 [2163783.001]
  • [Cites] J Am Acad Dermatol. 1999 Aug;41(2 Pt 1):225-31 [10426893.001]
  • [Cites] Facial Plast Surg. 2008 Jan;24(1):3-10 [18286429.001]
  • [Cites] J Clin Pathol. 2007 Feb;60(2):129-44 [16882696.001]
  • [Cites] HNO. 2007 Jun;55(6):497-510 [17486306.001]
  • [Cites] Handchir Mikrochir Plast Chir. 2007 Jun;39(3):181-8 [17602380.001]
  • [Cites] Acta Chir Plast. 2007;49(3):67-70 [18051585.001]
  • [Cites] J Clin Pathol. 2007 Feb;60(2):145-59 [16882695.001]
  • (PMID = 21253288.001).
  • [ISSN] 1827-675X
  • [Journal-full-title] Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale
  • [ISO-abbreviation] Acta Otorhinolaryngol Ital
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC3008151
  • [Keywords] NOTNLM ; Forehead flap / Microcystic adnexal carcinoma / Mustardé flap
  •  go-up   go-down


2. YASUNO K, NISHIYAMA S, SUETSUGU F, OGIHARA K, MADARAME H, SHIROTA K: Cutaneous clear cell adnexal carcinoma in a dog: special reference to cytokeratin expression. J Vet Med Sci; 2009 Nov;71(11):1513-7
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous clear cell adnexal carcinoma in a dog: special reference to cytokeratin expression.
  • Based on these findings, the tumor was diagnosed as canine clear cell adnexal carcinoma.

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19959904.001).
  • [ISSN] 0916-7250
  • [Journal-full-title] The Journal of veterinary medical science
  • [ISO-abbreviation] J. Vet. Med. Sci.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 68238-35-7 / Keratins
  •  go-up   go-down


3. Sakuma A, Nishiyama S, Yasuno K, Ohmuro T, Kamiie J, Shirota K: A case of canine cutaneous clear cell adnexal carcinoma with prominent expression of smooth muscle actin. J Toxicol Pathol; 2010 Dec;23(4):265-9
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of canine cutaneous clear cell adnexal carcinoma with prominent expression of smooth muscle actin.
  • Cutaneous clear cell adnexal carcinoma was found in the right lip of a 14-year-old male castrated Shih Tzu.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 22272037.001).
  • [ISSN] 1881-915X
  • [Journal-full-title] Journal of toxicologic pathology
  • [ISO-abbreviation] J Toxicol Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Other-IDs] NLM/ PMC3234631
  • [Keywords] NOTNLM ; cytokeratin / dermatopathology / dog / skin / skin tumor / stem cell
  •  go-up   go-down


Advertisement
4. Mahalingam M, Nguyen LP, Richards JE, Muzikansky A, Hoang MP: The diagnostic utility of immunohistochemistry in distinguishing primary skin adnexal carcinomas from metastatic adenocarcinoma to skin: an immunohistochemical reappraisal using cytokeratin 15, nestin, p63, D2-40, and calretinin. Mod Pathol; 2010 May;23(5):713-9
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The diagnostic utility of immunohistochemistry in distinguishing primary skin adnexal carcinomas from metastatic adenocarcinoma to skin: an immunohistochemical reappraisal using cytokeratin 15, nestin, p63, D2-40, and calretinin.
  • Often the distinction of primary adnexal carcinoma from metastatic adenocarcinoma to skin from breast, lung, and other sites can be a diagnostic dilemma.
  • We performed CK15 and nestin, as well as previously reported stains (such as p63, D2-40, and calretinin) on 113 cases (59 primary adnexal carcinomas and 54 cutaneous metastases).
  • Expressions of p63, CK15, nestin, D2-40, and calretinin were observed in 91, 40, 37, 44, and 14% of primary adnexal carcinoma, respectively, and in 8, 2, 8, 4, and 10% of cutaneous metastases, respectively. p63 appeared to be the most sensitive marker (with a sensitivity of 91%) in detecting primary adnexal carcinomas.
  • Using chi(2) analysis, statistically significant P-values (<0.05) were observed for p63, CK15, nestin, and D2-40 in the distinction of primary adnexal carcinoma versus cutaneous metastases.
  • In logistic regression and stepwise selection for predicting a primary adnexal carcinoma, statistical significance was observed for p63, CK15, and D2-40 (P-values: <0.001, 0.0275, and 0.0298, respectively) but not for nestin (P-value=0.4573).
  • Positive staining with all three markers argues in favor of a primary cutaneous adnexal neoplasm.
  • [MeSH-major] Adenocarcinoma / secondary. Biomarkers, Tumor / metabolism. Neoplasms, Adnexal and Skin Appendage / pathology. Skin Neoplasms / pathology. Skin Neoplasms / secondary
  • [MeSH-minor] Antibodies, Monoclonal / metabolism. Antibodies, Monoclonal, Murine-Derived. Calbindin 2. Chi-Square Distribution. Diagnosis, Differential. Humans. Immunohistochemistry. Intermediate Filament Proteins / metabolism. Keratin-15 / metabolism. Nerve Tissue Proteins / metabolism. Nestin. Regression Analysis. S100 Calcium Binding Protein G / metabolism. Sensitivity and Specificity. Trans-Activators / metabolism. Transcription Factors. Tumor Suppressor Proteins / metabolism

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • Faculty of 1000. commentaries/discussion - See the articles recommended by F1000Prime's Faculty of more than 8,000 leading experts in Biology and Medicine. (subscription/membership/fee required).
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20190734.001).
  • [ISSN] 1530-0285
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Biomarkers, Tumor; 0 / CALB2 protein, human; 0 / Calbindin 2; 0 / Intermediate Filament Proteins; 0 / Keratin-15; 0 / NES protein, human; 0 / Nerve Tissue Proteins; 0 / Nestin; 0 / S100 Calcium Binding Protein G; 0 / TP63 protein, human; 0 / Trans-Activators; 0 / Transcription Factors; 0 / Tumor Suppressor Proteins; 0 / monoclonal antibody D2-40
  •  go-up   go-down


5. Pennington BE, Leffell DJ: Mohs micrographic surgery: established uses and emerging trends. Oncology (Williston Park); 2005 Aug;19(9):1165-71; discussion 1171-2, 1175
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This approach appears to be superior to conventional surgical excision in the treatment of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), the two most common cancers of the skin.
  • Its efficacy in treating BCC and SCC has led clinicians to explore the role of Mohs micrographic surgery in the management of less common cutaneous neoplasms, such as melanoma, Merkel cell carcinoma, dermatofibrosarcoma protuberans, extramammary Paget's disease, and microcystic adnexal carcinoma.
  • [MeSH-minor] Adenoma / surgery. Carcinoma, Basal Cell / surgery. Carcinoma, Merkel Cell / surgery. Carcinoma, Squamous Cell / surgery. Dermatofibrosarcoma / surgery. Humans. Melanoma / surgery. Paget Disease, Extramammary / surgery. Skin Neoplasms / surgery

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16255133.001).
  • [ISSN] 0890-9091
  • [Journal-full-title] Oncology (Williston Park, N.Y.)
  • [ISO-abbreviation] Oncology (Williston Park, N.Y.)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


6. Clement CI, Genge J, O'Donnell BA, Lochhead AG: Orbital and periorbital microcystic adnexal carcinoma. Ophthal Plast Reconstr Surg; 2005 Mar;21(2):97-102
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Orbital and periorbital microcystic adnexal carcinoma.
  • PURPOSE: To review the clinical and histopathologic features of patients with microcystic adnexal carcinoma of the orbital and periorbital tissues.
  • All had initial histopathology diagnosed as squamous cell carcinoma but were subsequently diagnosed as microcystic adnexal carcinoma after clinical recurrence.
  • CONCLUSIONS: Review of the literature shows that microcystic adnexal carcinoma affecting the orbital and periorbital tissues is difficult to differentiate clinically and microscopically from other conditions including squamous cell carcinoma.
  • [MeSH-major] Carcinoma, Skin Appendage / pathology. Eyelid Neoplasms / pathology. Orbital Neoplasms / pathology. Skin Neoplasms / pathology

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15778661.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 27
  •  go-up   go-down


7. Jeon S, Paik JS, Yang SW: A case of microcystic adnexal carcinoma. Jpn J Ophthalmol; 2010 Jan;54(1):104-5
Genetic Alliance. consumer health - Microcystic adnexal carcinoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of microcystic adnexal carcinoma.
  • [MeSH-major] Carcinoma, Skin Appendage / pathology. Eyelid Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20151289.001).
  • [ISSN] 1613-2246
  • [Journal-full-title] Japanese journal of ophthalmology
  • [ISO-abbreviation] Jpn. J. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Carcinoembryonic Antigen; 0 / Keratin-15; 0 / Keratin-20
  •  go-up   go-down


8. Hansen T, Kingsley M, Mallatt BD, Krishnan R: Extrafacial microcystic adnexal carcinoma: case report and review of the literature. Dermatol Surg; 2009 Nov;35(11):1835-9
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extrafacial microcystic adnexal carcinoma: case report and review of the literature.
  • [MeSH-major] Carcinoma, Skin Appendage / pathology. Skin Neoplasms / pathology

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19691664.001).
  • [ISSN] 1524-4725
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Lewis Blood-Group System
  • [Number-of-references] 36
  •  go-up   go-down


9. Liyanage SE, Saleh GM, Rose GE, Luthert PJ, Beaconsfield M, Verity DH: Delayed diagnosis of microcystic adnexal carcinoma in progressive eyelid distortion. Arch Ophthalmol; 2010 Jan;128(1):132-5
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Delayed diagnosis of microcystic adnexal carcinoma in progressive eyelid distortion.
  • [MeSH-major] Epidermal Cyst / diagnosis. Eyelid Diseases / diagnosis. Eyelids / pathology. Orbital Diseases / diagnosis

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • MedlinePlus Health Information. consumer health - Eyelid Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20065232.001).
  • [ISSN] 1538-3601
  • [Journal-full-title] Archives of ophthalmology (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down


10. Seaward JR, Kalipershad SN, Ross GL: Supraorbital neuroma masquerading as local recurrence from a previously excised microcystic adnexal carcinoma. J Plast Reconstr Aesthet Surg; 2010 Mar;63(3):e239-41
Genetic Alliance. consumer health - Microcystic adnexal carcinoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Supraorbital neuroma masquerading as local recurrence from a previously excised microcystic adnexal carcinoma.
  • We present a case of a 53 year old gentleman with a previous history of a microcystic adnexal carcinoma in the supraorbital region who represented with pain and tenderness 3 years postoperatively.
  • [MeSH-major] Carcinoma, Skin Appendage / pathology. Neoplasm Recurrence, Local / diagnosis. Orbital Neoplasms / pathology. Sweat Gland Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans. Male. Middle Aged. Neuroma

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2009 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 19648071.001).
  • [ISSN] 1878-0539
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  •  go-up   go-down


11. Nadiminti H, Nadiminti U, Washington C: Microcystic adnexal carcinoma in African-Americans. Dermatol Surg; 2007 Nov;33(11):1384-7
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Microcystic adnexal carcinoma in African-Americans.
  • [MeSH-major] Carcinoma / pathology. Carcinoma / surgery. Head and Neck Neoplasms / pathology. Head and Neck Neoplasms / surgery. Scalp / surgery. Sweat Gland Neoplasms / pathology. Sweat Gland Neoplasms / surgery

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • MedlinePlus Health Information. consumer health - Head and Neck Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17958597.001).
  • [ISSN] 1524-4725
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


12. Krahl D, Sellheyer K: Monoclonal antibody Ber-EP4 reliably discriminates between microcystic adnexal carcinoma and basal cell carcinoma. J Cutan Pathol; 2007 Oct;34(10):782-7
Faculty of 1000. commentaries/discussion - See the articles recommended by F1000Prime's Faculty of more than 8,000 leading experts in Biology and Medicine. (subscription/membership/fee required).

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Monoclonal antibody Ber-EP4 reliably discriminates between microcystic adnexal carcinoma and basal cell carcinoma.
  • It is diagnostically highly reliable in the differentiation between basal cell carcinoma and cutaneous squamous cell carcinoma.
  • In this study, we report its application in the differential diagnosis of microcystic adnexal carcinoma, desmoplastic trichoepithelioma and basal cell carcinoma.
  • METHODS: Biopsy samples from 28 sclerosing and infiltrating basal cell carcinomas, 13 microcystic adnexal carcinomas and 16 desmoplastic trichoepitheliomas were examined after immunohistochemical staining with Ber-EP4.
  • RESULTS: Ber-EP4 did not label any of the microcystic adnexal carcinomas, whereas all 28 basal cell carcinomas were Ber-EP4 positive.
  • Only one basal cell carcinoma was weakly positive.
  • Twelve of the 16 desmoplastic trichoepitheliomas were immunoreactive with Ber-EP4 and the staining was more variable than those of basal cell carcinomas.
  • CONCLUSIONS: Ber-EP4 reliably differentiates microcystic adnexal carcinoma from basal cell carcinoma to the same extent as it distinguishes the latter tumor from squamous cell carcinoma.
  • While it stains the majority of desmoplastic trichoepitheliomas, these tumors still have to be considered in the differential diagnosis with microcystic adnexal carcinoma, when Ber-EP4 is applied.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Carcinoma, Basal Cell / diagnosis. Carcinoma, Skin Appendage / diagnosis. Skin / pathology. Skin Neoplasms / diagnosis
  • [MeSH-minor] Biopsy. Carcinoma, Squamous Cell / diagnosis. Carcinoma, Squamous Cell / metabolism. Diagnosis, Differential. Fluorescent Antibody Technique, Indirect. Humans. Sclerosis / pathology

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17880584.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / human epithelial antigen-125
  •  go-up   go-down


13. Yu Y, Finn DT, Rogers GS: Microcystic adnexal carcinoma: a rare, locally aggressive cutaneous tumor. Am J Clin Oncol; 2010 Apr;33(2):196-7
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Microcystic adnexal carcinoma: a rare, locally aggressive cutaneous tumor.
  • [MeSH-major] Carcinoma, Ductal / pathology. Carcinoma, Skin Appendage / pathology. Lymph Nodes / pathology. Skin Neoplasms / pathology

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentOn] Am J Clin Oncol. 2010 Apr;33(2):125-7 [19675445.001]
  • (PMID = 20375780.001).
  • [ISSN] 1537-453X
  • [Journal-full-title] American journal of clinical oncology
  • [ISO-abbreviation] Am. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] United States
  •  go-up   go-down


14. Redd MA, Bray DW, Royer M: Asymptomatic cutaneous lip plaque. Diagnosis: microcystic adnexal carcinoma (MAC). Arch Dermatol; 2007 Jun;143(6):791-6
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Asymptomatic cutaneous lip plaque. Diagnosis: microcystic adnexal carcinoma (MAC).
  • [MeSH-major] Carcinoma, Skin Appendage / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Aged. Diagnosis, Differential. Female. Humans. Lip / pathology

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17576952.001).
  • [ISSN] 0003-987X
  • [Journal-full-title] Archives of dermatology
  • [ISO-abbreviation] Arch Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


15. Merritt BG, Snow SN, Longley BJ: Desmoplastic trichoepithelioma, infiltrative/morpheaform BCC, and microcystic adnexal carcinoma: differentiation by immunohistochemistry and determining the need for Mohs micrographic surgery. Cutis; 2010 May;85(5):254-8
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoplastic trichoepithelioma, infiltrative/morpheaform BCC, and microcystic adnexal carcinoma: differentiation by immunohistochemistry and determining the need for Mohs micrographic surgery.
  • Desmoplastic trichoepithelioma (DTE), infiltrative/morpheaform basal cell carcinoma (BCC), and microcystic adnexal carcinoma (MAC) are tumors in this category that may be difficult to differentiate, especially when evaluating thin biopsy specimens.
  • An accurate diagnosis has important clinical implications.
  • [MeSH-major] Carcinoma, Basal Cell / pathology. Carcinoma, Skin Appendage / pathology. Mohs Surgery. Skin Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans. Immunohistochemistry. Keratin-20. Male. Middle Aged. Staining and Labeling

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20540416.001).
  • [ISSN] 0011-4162
  • [Journal-full-title] Cutis
  • [ISO-abbreviation] Cutis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Keratin-20
  •  go-up   go-down


16. Fernández-Figueras MT, Montero MA, Admella J, de la Torre N, Quer A, Ariza A: High (nuclear) grade adnexal carcinoma with microcystic adnexal carcinoma-like structural features. Am J Dermatopathol; 2006 Aug;28(4):346-51
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] High (nuclear) grade adnexal carcinoma with microcystic adnexal carcinoma-like structural features.
  • Microcystic adnexal carcinoma (MAC) is a slow growing, locally aggressive sweat gland tumor.
  • Microscopically, MAC is characterized by a stratified proliferation of microcysts, cords, and ducts of cells that show squamous or adnexal differentiation.
  • We report a case of adnexal carcinoma with architectural features of MAC that displayed also marked nuclear pleomorphism and hyperchromasia with squamous pearl formation and a widespread strong p53 immunoreaction.
  • We therefore want to sound an alert about the possible existence of tumors displaying microscopic findings characteristic of the aggressive forms of sweat gland carcinoma (nuclear pleomorphism and hyperchromasia, vascular invasion, and necrosis) in addition to architectural features of MAC.

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16871041.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Tumor Suppressor Protein p53
  •  go-up   go-down


17. Schulman FY, Lipscomb TP, Atkin TJ: Canine cutaneous clear cell adnexal carcinoma: histopathology, immunohistochemistry, and biologic behavior of 26 cases. J Vet Diagn Invest; 2005 Sep;17(5):403-11
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Canine cutaneous clear cell adnexal carcinoma: histopathology, immunohistochemistry, and biologic behavior of 26 cases.
  • The findings are consistent with a poorly differentiated, low-grade, adnexal carcinoma of the skin.
  • Similar canine cutaneous neoplasms have been reported as "clear-cell hidradenocarcinoma" and "follicular stem cell carcinoma."
  • The authors propose the designation "cutaneous clear cell adnexal carcinoma. "
  • [MeSH-major] Adenocarcinoma, Clear Cell / veterinary. Carcinoma, Skin Appendage / veterinary. Dog Diseases / pathology. Skin Neoplasms / veterinary

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16312230.001).
  • [ISSN] 1040-6387
  • [Journal-full-title] Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
  • [ISO-abbreviation] J. Vet. Diagn. Invest.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


18. Wetter R, Goldstein GD: Microcystic adnexal carcinoma: a diagnostic and therapeutic challenge. Dermatol Ther; 2008 Nov-Dec;21(6):452-8
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Microcystic adnexal carcinoma: a diagnostic and therapeutic challenge.
  • Microcystic adnexal carcinoma (MAC) is a rare cutaneous neoplasm that is often diagnosed after having been present for a significant period of time.
  • Actual skin involvement is significantly more extensive than can be determined clinically and because of this, therapy is challenging.
  • Though metastasis is rare, there have been reports of both regional and distant metastatic disease.
  • [MeSH-major] Carcinoma, Skin Appendage / therapy. Skin Neoplasms / therapy

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19076623.001).
  • [ISSN] 1529-8019
  • [Journal-full-title] Dermatologic therapy
  • [ISO-abbreviation] Dermatol Ther
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Denmark
  • [Number-of-references] 67
  •  go-up   go-down


19. Kavand S, Cassarino DS: "Squamoid eccrine ductal carcinoma": an unusual low-grade case with follicular differentiation. Are these tumors squamoid variants of microcystic adnexal carcinoma? Am J Dermatopathol; 2009 Dec;31(8):849-52
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] "Squamoid eccrine ductal carcinoma": an unusual low-grade case with follicular differentiation. Are these tumors squamoid variants of microcystic adnexal carcinoma?
  • Squamoid eccrine ductal carcinoma is a rare primary cutaneous tumor exhibiting both squamous and adnexal ductal differentiation.
  • The cell of origin of these tumors is unknown, and they have been classified both as variants of cutaneous squamous cell carcinoma and as a type of eccrine carcinoma.
  • We report an additional case of a slow-growing tumor, occurring on the great toe of a 61-year-old woman, which was unusual as it showed follicular differentiation in addition to squamoid and ductal areas.
  • We postulate that these tumors may be closely related to microcystic adnexal carcinoma and similarly show differentiation along both follicular and ductal lines, likely indicating folliculosebaceous-apocrine, rather than eccrine, origin or differentiation.
  • [MeSH-major] Carcinoma, Skin Appendage / pathology. Carcinoma, Squamous Cell / pathology. Eccrine Glands / pathology. Hair Follicle / pathology. Skin Neoplasms / pathology

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19786851.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


20. Gomez-Maestra MJ, España-Gregori E, Aviñó-Martinez JA, Mancheño-Franch N, Peña S: Brainstem and cavernous sinus metastases arising from a microcystic adnexal carcinoma of the eyebrow by perineural spreading. Can J Ophthalmol; 2009 Jun;44(3):e17-8
MedlinePlus Health Information. consumer health - Eye Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Brainstem and cavernous sinus metastases arising from a microcystic adnexal carcinoma of the eyebrow by perineural spreading.

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19506589.001).
  • [ISSN] 1715-3360
  • [Journal-full-title] Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
  • [ISO-abbreviation] Can. J. Ophthalmol.
  • [Language] ENG
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
  •  go-up   go-down


21. Auersperg N: Re: "Cultures of ovarian surface epithelium from women with and without a hereditary predisposition to develop female adnexal carcinoma". Gynecol Oncol; 2005 Apr;97(1):302-4; author reply 304-5
MedlinePlus Health Information. consumer health - Uterine Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Re: "Cultures of ovarian surface epithelium from women with and without a hereditary predisposition to develop female adnexal carcinoma".
  • [MeSH-minor] Adnexa Uteri / pathology. Epithelial Cells / cytology. Female. Genetic Predisposition to Disease. Humans

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentOn] Gynecol Oncol. 2004 Mar;92(3):819-26 [14984947.001]
  • (PMID = 15790484.001).
  • [ISSN] 0090-8258
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] United States
  •  go-up   go-down


22. Wang SQ, Goldberg LH, Nemeth A: The merits of adding toluidine blue-stained slides in Mohs surgery in the treatment of a microcystic adnexal carcinoma. J Am Acad Dermatol; 2007 Jun;56(6):1067-9
Genetic Alliance. consumer health - Microcystic adnexal carcinoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The merits of adding toluidine blue-stained slides in Mohs surgery in the treatment of a microcystic adnexal carcinoma.
  • [MeSH-major] Carcinoma / surgery. Coloring Agents. Mohs Surgery. Sweat Gland Neoplasms / surgery. Tolonium Chloride
  • [MeSH-minor] Humans. Neoplasm Invasiveness. Skin Neoplasms. Staining and Labeling / methods

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17504725.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Letter
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Coloring Agents; 15XUH0X66N / Tolonium Chloride
  •  go-up   go-down


23. Prandl EC, Arbab E, Schintler MV, Koch H, Scharnagl E: Microcystic adnexal carcinoma in the nasolabial area: resection and reconstruction with a free fasciocutaneous lateral arm flap with a sandwich technique. Dermatol Surg; 2007 Mar;33(3):378-81
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Microcystic adnexal carcinoma in the nasolabial area: resection and reconstruction with a free fasciocutaneous lateral arm flap with a sandwich technique.

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • MedlinePlus Health Information. consumer health - Plastic and Cosmetic Surgery.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17338702.001).
  • [ISSN] 1076-0512
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


24. Nagatsuka H, Rivera RS, Gunduz M, Siar CH, Tamamura R, Mizukawa N, Asaumi J, Nagai N: Microcystic adnexal carcinoma with mandibular bone marrow involvement: a case report with immunohistochemistry. Am J Dermatopathol; 2006 Dec;28(6):518-22
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Microcystic adnexal carcinoma with mandibular bone marrow involvement: a case report with immunohistochemistry.
  • Microcystic adnexal carcinoma is a rare, locally aggressive cutaneous neoplasm with a high probability of persistence locally but a low probability of metastasis.
  • We report a case of a 69-year-old female patient with an indurated plaque at the mental region.
  • Our results indicate that microcystic adnexal carcinoma consists of tumor cells capable of both follicular and eccrine differentiation.
  • [MeSH-major] Carcinoma, Skin Appendage / pathology. Lip Neoplasms / pathology. Mandibular Neoplasms / pathology. Skin Neoplasms / pathology

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17122497.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Carcinoembryonic Antigen; 0 / S100 Proteins
  •  go-up   go-down


25. Kamiya H, Kitajima Y, Ban M: Bowen's disease with invasive adnexal carcinoma: the pluripotential nature of Bowen's disease cells. J Dermatol; 2006 Dec;33(12):858-64
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bowen's disease with invasive adnexal carcinoma: the pluripotential nature of Bowen's disease cells.
  • Bowen's disease rarely exhibits multiple combinations of premalignant and/or malignant skin lesions.
  • Bowen's disease with invasive adnexal carcinoma was originally described by Kao, but is not well recognized by clinicians due to its rarity and lack of specific clinical features of this condition.
  • Herein, we describe three unusual cases of Bowen's disease with invasive adnexal carcinoma.
  • The plaque lesions possessed clinical features typical of Bowen's disease.
  • In cases 1 and 3, we confirmed the adnexal tumor within tumors of Bowen's disease, the diagnosis of which is eccrine porocarcinoma.
  • The tumor in case 2 was characteristic to trichilemmal carcinoma.
  • Immunohistochemically, the tumor cells of Bowen's disease and the adnexal carcinoma differed in antigenicities.
  • The present cases support a notion that Bowen's disease maintains a pluripotential nature.
  • [MeSH-major] Bowen's Disease / pathology. Carcinoma, Skin Appendage / pathology. Cell Transformation, Neoplastic / pathology. Skin Neoplasms / pathology

  • Genetic Alliance. consumer health - Bowen's Disease.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17169090.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


26. Schaller J, Rytina E, Rütten A, Hendricks C, Ha T, Requena L: Sweat duct proliferation associated with aggregates of elastic tissue and atrophodermia vermiculata: a simulator of microcystic adnexal carcinoma. Report of two cases. J Cutan Pathol; 2010 Sep;37(9):1002-9
Genetic Alliance. consumer health - Atrophodermia Vermiculata.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sweat duct proliferation associated with aggregates of elastic tissue and atrophodermia vermiculata: a simulator of microcystic adnexal carcinoma. Report of two cases.
  • Microcystic adnexal carcinoma (MAC) is a rare, usually solitary, slowly growing, yet aggressive neoplasm with a tendency for local recurrences.
  • However, to our knowledge, the presence of a MAC-like ductal proliferation embedded in sclerotic stroma and extending to the deep dermis has not been previously described.
  • [MeSH-major] Adenoma / diagnosis. Facial Dermatoses / pathology. Hair Follicle / pathology. Neoplasms, Adnexal and Skin Appendage / diagnosis. Skin / pathology. Sweat Glands / pathology
  • [MeSH-minor] Adult. Atrophy / pathology. Biopsy. Cell Proliferation. Diagnosis, Differential. Elastic Tissue / pathology. Female. Hamartoma / diagnosis. Humans. Male. Neoplasms, Multiple Primary / pathology. Sweat Gland Neoplasms / diagnosis

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20175822.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  •  go-up   go-down


27. Eisen DB, Zloty D: Microcystic adnexal carcinoma involving a large portion of the face: when is surgery not reasonable? Dermatol Surg; 2005 Nov;31(11 Pt 1):1472-7; discussion 1478
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Microcystic adnexal carcinoma involving a large portion of the face: when is surgery not reasonable?
  • BACKGROUND: We report a case of microcystic adnexal carcinoma (MAC) involving a large portion of the face, one of the largest of any MAC reported thus far in this area, and review the literature regarding the nature of the tumor and available treatments.
  • OBJECTIVE: To review the literature about what is known about therapy for MAC and what options are available to patients who have this disease.
  • [MeSH-major] Carcinoma, Skin Appendage / pathology. Facial Neoplasms / pathology

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16416625.001).
  • [ISSN] 1076-0512
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 47
  •  go-up   go-down


28. Yu JB, Blitzblau RC, Patel SC, Decker RH, Wilson LD: Surveillance, Epidemiology, and End Results (SEER) database analysis of microcystic adnexal carcinoma (sclerosing sweat duct carcinoma) of the skin. Am J Clin Oncol; 2010 Apr;33(2):125-7
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surveillance, Epidemiology, and End Results (SEER) database analysis of microcystic adnexal carcinoma (sclerosing sweat duct carcinoma) of the skin.
  • BACKGROUND: Microcystic adnexal carcinoma (MAC) is a very rare cancer of the skin.
  • Predominant site of disease was the head and neck skin (74%).
  • There was only 1 case of recorded metastatic disease.
  • [MeSH-major] Carcinoma, Ductal / pathology. Carcinoma, Skin Appendage / pathology. Skin Neoplasms / pathology

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Am J Clin Oncol. 2010 Apr;33(2):196-7 [20375780.001]
  • (PMID = 19675445.001).
  • [ISSN] 1537-453X
  • [Journal-full-title] American journal of clinical oncology
  • [ISO-abbreviation] Am. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


29. DuPont NC, Mabuchi S, Ries S, Berman ML: Sclerosing ductal carcinoma of the clitoris with microcystic adnexal carcinoma-like features. J Cutan Pathol; 2009 Mar;36(3):359-61
Genetic Alliance. consumer health - Microcystic adnexal carcinoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sclerosing ductal carcinoma of the clitoris with microcystic adnexal carcinoma-like features.
  • Primary clitoral malignancies are rare and most are invasive squamous cell carcinomas.
  • Microcystic adnexal carcinoma (MAC) is an indolent, rare dermatologic carcinoma that typically affects the head and neck region.
  • MAC is a cutaneous carcinoma rarely found on the vulva.
  • It is a slow growing but locally aggressive carcinoma that is best treated with surgical resection.
  • Sclerosing ductal carcinomas may have MAC-like features, and the diagnosis and management of one case is provided here.
  • [MeSH-major] Carcinoma, Ductal / pathology. Carcinoma, Ductal / surgery. Clitoris / pathology. Clitoris / surgery. Genital Neoplasms, Female / pathology. Genital Neoplasms, Female / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19220633.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  •  go-up   go-down


30. Kazakov DV, Kutzner H, Mukensnabl P, Michal M: Low-grade adnexal carcinoma of the skin with multidirectional (glandular, trichoblastomatous, spiradenocylindromatous) differentiation. Am J Dermatopathol; 2006 Aug;28(4):341-5
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Low-grade adnexal carcinoma of the skin with multidirectional (glandular, trichoblastomatous, spiradenocylindromatous) differentiation.
  • The conjoint occurrence of follicular, sebaceous, or apocrine differentiations in a cutaneous adnexal neoplasm is a known event, more often encountered in benign neoplasms, whereas reports of cutaneous malignant adnexal tumors with bilineage or trilineage differentiation are few.
  • A new case of a cutaneous malignant adnexal neoplasm with multidirectional differentiation is reported here.
  • A 57-year-old woman presented with a long-standing, slowly growing, asymptomatic solitary tumor the size of a large nut in the coccygeal area, which was surgically excised.
  • We classified this tumor as a well-differentiated adnexal carcinoma demonstrating combined follicular and apocrine differentiation.
  • It differs from previously published cases of malignant adnexal tumors with multidirectional differentiation and further exemplifies the spectrum of diversity encountered in malignant proliferations with differentiation toward the folliculosebaceous-apocrine unit.
  • [MeSH-major] Adnexal Diseases / pathology. Cell Differentiation. Skin Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16871040.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


31. Matsushita S, Uemura T, Imayama S, Sugihara H, Yamasaki M: Giant microcystic adnexal carcinoma of the scalp. J Dermatol; 2008 Nov;35(11):726-8
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant microcystic adnexal carcinoma of the scalp.
  • Microcystic adnexal carcinoma (MAC) is an uncommon, locally aggressive tumor.
  • Resection included the cranium; for reconstruction we used a titan mesh allograft and covered it with a free latissimus dorsi muscle flap and a mesh skin graft.
  • Ours is the first case of a MAC measuring more than 100 cm2 arising on the scalp of an individual in the third decade of life.
  • [MeSH-major] Carcinoma, Skin Appendage / pathology. Scalp / pathology. Skin Neoplasms / pathology

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [ErratumIn] J Dermatol. 2008 Dec;35(12):808
  • (PMID = 19120767.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


32. Fang W, Chen D, Shang JF, Wang F, Xiao L: [Microcystic adnexal carcinoma: report of two cases]. Zhonghua Bing Li Xue Za Zhi; 2009 Jan;38(1):59-60
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Microcystic adnexal carcinoma: report of two cases].
  • [MeSH-major] Carcinoma, Skin Appendage / pathology. Head and Neck Neoplasms / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adult. Arm. Carcinoembryonic Antigen / metabolism. Carcinoma, Basal Cell / pathology. Diagnosis, Differential. Humans. Male. Middle Aged. Mucin-1 / metabolism

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • MedlinePlus Health Information. consumer health - Head and Neck Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19489229.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Carcinoembryonic Antigen; 0 / Mucin-1
  •  go-up   go-down


33. Beer KT, Bühler SS, Mullis P, Laeng RH, Greiner R: A microcystic adnexal carcinoma in the auditory canal 15 years after radiotherapy of a 12-year-old boy with nasopharynx carcinoma. Strahlenther Onkol; 2005 Jun;181(6):405-10
MedlinePlus Health Information. consumer health - Radiation Therapy.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A microcystic adnexal carcinoma in the auditory canal 15 years after radiotherapy of a 12-year-old boy with nasopharynx carcinoma.
  • BACKGROUND: Radiogenic malignancies require cure of the primary disease and a prolonged survival.
  • CASE REPORT: A 12-year-old boy is reported who suffered from an advanced nasopharynx carcinoma and was treated with radical irradiation in 1983.
  • 15 years later he developed a rare microcystic adnexal carcinoma of the auditory canal inside the volume of the target dose.
  • The secondary malignant neoplasm was resected and required another radiation treatment (1 Gy b.i.d.) due to involved margins.
  • DISCUSSION AND LITERATURE REVIEW: The entity of microcystic carcinoma is discussed with a review of the literature on biology, diagnosis, and treatment.
  • [MeSH-major] Carcinoma / surgery. Ear Neoplasms / surgery. Nasopharyngeal Neoplasms / radiotherapy. Radiotherapy / adverse effects

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15925985.001).
  • [ISSN] 0179-7158
  • [Journal-full-title] Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]
  • [ISO-abbreviation] Strahlenther Onkol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Cobalt Radioisotopes
  •  go-up   go-down


34. Palamaras I, McKenna JD, Robson A, Barlow RJ: Microcystic adnexal carcinoma: a case series treated with mohs micrographic surgery and identification of patients in whom paraffin sections may be preferable. Dermatol Surg; 2010 Apr;36(4):446-52
Genetic Alliance. consumer health - Microcystic adnexal carcinoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Microcystic adnexal carcinoma: a case series treated with mohs micrographic surgery and identification of patients in whom paraffin sections may be preferable.
  • BACKGROUND: Microcystic adnexal carcinoma (MAC) is a rare cutaneous tumor characterized by aggressive local infiltration, including a high propensity for perineural invasion (PNI).
  • [MeSH-major] Carcinoma / pathology. Carcinoma / surgery. Facial Neoplasms / pathology. Facial Neoplasms / surgery. Mohs Surgery / methods. Neoplasms, Adnexal and Skin Appendage / pathology. Neoplasms, Adnexal and Skin Appendage / surgery
  • [MeSH-minor] Adult. Aged. Eye Enucleation. Female. Frozen Sections. Humans. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm, Residual / diagnosis. Neoplasm, Residual / pathology. Neoplasm, Residual / surgery. Orbital Neoplasms / pathology. Orbital Neoplasms / surgery. Photomicrography. Retrospective Studies. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20180834.001).
  • [ISSN] 1524-4725
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


35. Page RN, Hanggi MC, King R, Googe PB: Multiple microcystic adnexal carcinomas. Cutis; 2007 Apr;79(4):299-303
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multiple microcystic adnexal carcinomas.
  • Microcystic adnexal carcinoma (MAC) is a relatively uncommon adnexal neoplasm that can demonstrate locally aggressive behavior; rare instances of metastatic lesions have been reported.
  • We report a case of a 34-year-old black man with multiple primary MACs.
  • [MeSH-major] Carcinoma, Skin Appendage / pathology. Neoplasms, Multiple Primary / pathology. Skin Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17500378.001).
  • [ISSN] 0011-4162
  • [Journal-full-title] Cutis
  • [ISO-abbreviation] Cutis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


36. Rütten A, Requena L: [Sweat gland carcinomas of the skin]. Hautarzt; 2008 Feb;59(2):151-60

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Sweat gland carcinomas of the skin].
  • Sweat gland carcinomas are rare malignant tumors of the skin.
  • The well-defined entities porocarcinoma, microcystic adnexal carcinoma, aggressive digital papillary adenocarcinoma, mucinous eccrine carcinoma, adenoid cystic carcinoma, spiradenocarcinoma, cylindrocarcinoma, hidradenocarcinoma are described.
  • [MeSH-major] Sweat Gland Neoplasms / diagnosis. Sweat Gland Neoplasms / therapy

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18214401.001).
  • [ISSN] 1432-1173
  • [Journal-full-title] Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete
  • [ISO-abbreviation] Hautarzt
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 20
  •  go-up   go-down


37. Hamsch C, Hartschuh W: Microcystic adnexal carcinoma - aggressive infiltrative tumor often with innocent clinical appearance. J Dtsch Dermatol Ges; 2010 Apr;8(4):275-8
MedlinePlus Health Information. consumer health - Oral Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Microcystic adnexal carcinoma - aggressive infiltrative tumor often with innocent clinical appearance.
  • Microcystic adnexal carcinoma is a rare sweat gland malignancy, characterized by slow, but aggressive infiltrative growth.
  • We report two patients with microcystic adnexal carcinoma, using them as a basis to discuss, pathogenesis, diagnosis, histology and therapy of the tumor.

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19788582.001).
  • [ISSN] 1610-0387
  • [Journal-full-title] Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
  • [ISO-abbreviation] J Dtsch Dermatol Ges
  • [Language] eng; ger
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


38. Jakobiec FA, Hanna E, Townsend DJ: Basal cell carcinoma of the eyelid with exceptional histomorphologic expressions. Ophthal Plast Reconstr Surg; 2009 May-Jun;25(3):232-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Basal cell carcinoma of the eyelid with exceptional histomorphologic expressions.
  • A basal cell carcinoma of the eyelid had unique and potentially confusing histopathologic features.
  • The tumor displayed a carcinoma in situ pattern with replacement of an extensive segment of the tarsal epithelium by neoplastic basaloid cells, a finding to the best of the authors' knowledge that has not been previously documented.
  • Within the infiltrating component of the dermis were classical solid basaloid nests and lobules; they were accompanied, however, by a separate and exceptionally prominent component of duct-like (pseudoglandular) units mimicking a microcystic adnexal carcinoma.
  • [MeSH-major] Carcinoma, Basal Cell / pathology. Eyelid Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19454940.001).
  • [ISSN] 1537-2677
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


39. Martorell-Calatayud A, Requena-Caballero C, Botella-Estrada R, Almenar-Medina S, Sanmartín-Jiménez O, Llombart-Cussac B, Nagore-Enguídanos E, Serra-Guillén C, Echeverría-García B, Guillén-Barona C: [Microcystic adnexal carcinoma: Mohs micrographic surgery as the treatment of choice]. Actas Dermosifiliogr; 2009 Oct;100(8):693-9
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Microcystic adnexal carcinoma: Mohs micrographic surgery as the treatment of choice].
  • [Transliterated title] Carcinoma anexial microquístico: la cirugía micrográfica de Mohs como tratamiento de elección.
  • INTRODUCTION AND OBJECTIVES: Microcystic adnexal carcinoma is a rare and aggressive tumor that manifests clinically as a subcutaneous nodule located on the head or neck.
  • The tumor can be confused clinically and histologically with other benign and malignant skin lesions, often leading to inappropriate initial treatment.
  • The chief concern with microcystic adnexal carcinoma is the elevated morbidity and the high rate of recurrence after wide local excision.
  • MATERIAL AND METHODS: We reviewed the medical histories of 6 consecutive patients with microcystic adnexal carcinoma who underwent Mohs micrographic surgery in our dermatology department between 1995 and 2007.
  • Seventy percent of the tumors were wrongly diagnosed initially as basal cell carcinoma.
  • The site and the absence of recurrence in all our patients who underwent Mohs micrographic surgery support the use of this technique as the treatment of choice in microcystic adnexal carcinoma.
  • [MeSH-major] Carcinoma / surgery. Facial Neoplasms / surgery. Mohs Surgery. Skin Neoplasms / surgery

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19775547.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
  •  go-up   go-down


40. Dim-Jamora KC, Perone JB: Management of cutaneous tumors with mohs micrographic surgery. Semin Plast Surg; 2008 Nov;22(4):247-56

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We discuss the use of Mohs micrographic surgery for the following cutaneous tumors: basal cell carcinoma, squamous cell carcinoma, melanoma in situ, dermatofibrosarcoma protuberans, Merkel cell carcinoma, microcystic adnexal carcinoma, atypical fibroxanthoma, and sebaceous carcinoma.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Lancet. 1996 Mar 16;347(9003):735-8 [8602006.001]
  • [Cites] J Am Acad Dermatol. 1996 Jul;35(1):82-7 [8682970.001]
  • [Cites] J Am Acad Dermatol. 1995 Feb;32(2 Pt 1):233-6 [7829708.001]
  • [Cites] Lancet. 1994 Feb 19;343(8895):433-4 [7905951.001]
  • [Cites] Cancer. 1994 Jun 15;73(12):2964-70 [8199993.001]
  • [Cites] Clin Plast Surg. 1993 Jan;20(1):149-56 [8420703.001]
  • [Cites] J Am Acad Dermatol. 1993 Nov;29(5 Pt 2):840-5 [8408823.001]
  • [Cites] Otolaryngol Clin North Am. 1993 Apr;26(2):185-202 [8460037.001]
  • [Cites] J Dermatol Surg Oncol. 1991 Aug;17(8):681-4 [1885833.001]
  • [Cites] Dermatol Clin. 1989 Oct;7(4):833-43 [2676291.001]
  • [Cites] Dermatol Clin. 1989 Oct;7(4):609-11 [2676280.001]
  • [Cites] J Dermatol Surg Oncol. 1989 Mar;15(3):315-28 [2646336.001]
  • [Cites] N J Med. 1989 May;86(5):369-73 [2739948.001]
  • [Cites] J Am Acad Dermatol. 1986 Apr;14(4):668-73 [3958277.001]
  • [Cites] Eye (Lond). 1990;4 ( Pt 1):160-8 [2323467.001]
  • [Cites] Head Neck Surg. 1983 Jan-Feb;5(3):197-203 [6841116.001]
  • [Cites] Arch Dermatol. 1974 Aug;110(2):231-2 [4853214.001]
  • [Cites] Plast Reconstr Surg. 2004 Jun;113(7):2233; author reply 2233-4 [15253235.001]
  • [Cites] Arch Dermatol. 2004 Jun;140(6):736-42 [15210467.001]
  • [Cites] Clin Plast Surg. 2004 Jan;31(1):5-31 [15022790.001]
  • [Cites] Plast Reconstr Surg. 2002 Nov;110(6):1601 [12409793.001]
  • [Cites] Dermatol Surg. 2002 Aug;28(8):656-65 [12174054.001]
  • [Cites] Semin Oncol. 2002 Aug;29(4):336-40 [12170436.001]
  • [Cites] Dermatol Surg. 2002 Jul;28(7):623-31 [12135523.001]
  • [Cites] Br J Dermatol. 2002 Jan;146(1):18-25 [11841362.001]
  • [Cites] J Am Acad Dermatol. 2001 Oct;45(4):579-86 [11568750.001]
  • [Cites] Arch Facial Plast Surg. 2001 Jul-Sep;3(3):202-6 [11497507.001]
  • [Cites] J Am Acad Dermatol. 2001 Jun;44(6):1004-9 [11369914.001]
  • [Cites] Dermatol Surg. 2001 Apr;27(4):401-8 [11298716.001]
  • [Cites] Dermatol Surg. 2000 Aug;26(8):771-84 [10940065.001]
  • [Cites] Dermatol Surg. 2000 Apr;26(4):303-7 [10759814.001]
  • [Cites] Aust N Z J Surg. 2000 May;70(5):358-61 [10830600.001]
  • [Cites] Cancer. 2000 Apr 15;88(8):1842-51 [10760761.001]
  • [Cites] Dermatol Surg. 2007 Apr;33(4):395-402 [17430372.001]
  • [Cites] Skin Therapy Lett. 2007 Mar;12(2):6-9 [17393051.001]
  • [Cites] Ophthalmology. 2007 Jan;114(1):187-92 [17140665.001]
  • [Cites] Arch Dermatol. 2006 Feb;142(2):187-94 [16490846.001]
  • [Cites] Dermatol Surg. 2005 Nov;31(11 Pt 1):1428-33 [16416612.001]
  • [Cites] Dermatol Surg. 2005 Sep;31(9 Pt 1):1094-9; discussion 1100 [16164856.001]
  • [Cites] Curr Surg. 2005 Sep-Oct;62(5):518-26 [16125611.001]
  • [Cites] Arch Facial Plast Surg. 2005 Sep-Oct;7(5):342-6 [16172346.001]
  • [Cites] J Craniofac Surg. 2005 May;16(3):439-43 [15915111.001]
  • [Cites] Dermatol Surg. 2005 Jan;31(1):10-5 [15720088.001]
  • [Cites] Dermatol Surg. 2004 Dec;30(12 Pt 1):1479-85 [15606735.001]
  • [Cites] Lancet. 2004 Nov 13-19;364(9447):1766-72 [15541449.001]
  • [Cites] Am J Otolaryngol. 2004 Nov-Dec;25(6):385-93 [15547806.001]
  • [Cites] J Am Acad Dermatol. 1998 Nov;39(5 Pt 1):698-703 [9810885.001]
  • [Cites] Semin Cutan Med Surg. 1998 Jun;17(2):80-95 [9669602.001]
  • [Cites] J Am Acad Dermatol. 1998 Jul;39(1):79-97 [9674401.001]
  • [Cites] Dermatol Surg. 1997 Nov;23(11):1061-6 [9391565.001]
  • [Cites] Dermatol Surg. 1997 Oct;23(10):929-33 [9357504.001]
  • [Cites] Dermatol Surg. 1997 Feb;23(2):105-10 [9107284.001]
  • [Cites] J Am Acad Dermatol. 1995 Jul;33(1):1-15; quiz 16-8 [7601925.001]
  • (PMID = 20567701.001).
  • [ISSN] 1536-0067
  • [Journal-full-title] Seminars in plastic surgery
  • [ISO-abbreviation] Semin Plast Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2884874
  • [Keywords] NOTNLM ; Mohs micrographic surgery / cutaneous oncology / skin cancer
  •  go-up   go-down


41. Hoang MP, Dresser KA, Kapur P, High WA, Mahalingam M: Microcystic adnexal carcinoma: an immunohistochemical reappraisal. Mod Pathol; 2008 Feb;21(2):178-85
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Microcystic adnexal carcinoma: an immunohistochemical reappraisal.
  • Even though immunohistochemical comparisons of microcystic adnexal carcinoma vs infiltrative basal cell carcinoma and desmoplastic trichoepithelioma exist, they are mostly restricted to the use of a single stain.
  • In addition, a comparison with squamous cell carcinoma has not been reported previously.
  • In this study, we compare the expression of cytokeratin (CK) 15, CK7, CK20, CK903, carcinoembryonic antigen (CEA), CD10, CD15 and BerEP4 in 13 microcystic adnexal carcinoma, eight desmoplastic trichoepithelioma, 10 infiltrative basal cell carcinoma, and eight squamous cell carcinoma of which five exhibited ductal differentiation.
  • We found that the majority of microcystic adnexal carcinoma (92%) and desmoplastic trichoepithelioma (100%) cases expressed CK15 while the infiltrative basal cell carcinoma and squamous cell carcinoma cases were all negative.
  • Forty percent of infiltrative basal cell carcinoma expressed CK7; while only two microcystic adnexal carcinoma cases (15%) and one squamous cell carcinoma with ductal differentiation (12%) expressed CK7 in the remaining three tumor categories.
  • While the neoplastic cells were negative, luminal staining of ductal structures was noted for CK7, CD15 and CEA in some of the microcystic adnexal carcinoma, desmoplastic trichoepithelioma and squamous cell carcinoma with ductal differentiation cases.
  • Sixty percent of infiltrative basal cell carcinoma, 31% of microcystic adnexal carcinoma, and 25% of squamous cell carcinoma express CD10.
  • BerEP4 expression was noted in 38% of microcystic adnexal carcinoma, 57% of desmoplastic trichoepithelioma, 100% of infiltrative basal cell carcinoma, and 38% of squamous cell carcinoma.
  • In conclusion, we found CK15 to be a useful marker in distinguishing microcystic adnexal carcinoma from infiltrative basal cell carcinoma and squamous cell carcinoma with ductal differentiation.
  • Our experience indicates that microcystic adnexal carcinoma and desmoplastic trichoepithelioma have a similar immunohistochemical profile that is, CK15+ and BerEP4+/-; thus, additional studies are needed to separate these two entities.
  • [MeSH-major] Biomarkers, Tumor / analysis. Carcinoma, Skin Appendage / chemistry. Head and Neck Neoplasms / chemistry. Immunohistochemistry / methods. Skin Neoplasms / chemistry
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Basal Cell / chemistry. Carcinoma, Basal Cell / diagnosis. Carcinoma, Squamous Cell / chemistry. Carcinoma, Squamous Cell / diagnosis. Diagnosis, Differential. Female. Humans. Keratin-15 / analysis. Male. Middle Aged

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • MedlinePlus Health Information. consumer health - Head and Neck Cancer.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18065959.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Keratin-15; 0 / human epithelial antigen-125
  •  go-up   go-down


42. Plaza JA, Ortega PF, Stockman DL, Suster S: Value of p63 and podoplanin (D2-40) immunoreactivity in the distinction between primary cutaneous tumors and adenocarcinomas metastatic to the skin: a clinicopathologic and immunohistochemical study of 79 cases. J Cutan Pathol; 2010 Apr;37(4):403-10
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Value of p63 and podoplanin (D2-40) immunoreactivity in the distinction between primary cutaneous tumors and adenocarcinomas metastatic to the skin: a clinicopathologic and immunohistochemical study of 79 cases.
  • The distinction of metastatic carcinomas to the skin from poorly differentiated primary cutaneous carcinomas and sometimes primary benign adnexal tumors can pose a significant diagnostic challenge.
  • The purpose of this study was to evaluate the role of p63 and podoplanin (D2-40) immunoreactivity for separating primary skin tumors vs. cutaneous metastases of carcinomas from internal organs.
  • The 37 primary cutaneous tumors included 14 cases of benign adnexal tumors, 9 malignant skin adnexal neoplasms, and 14 primary squamous and basal cell carcinomas.
  • The 42 metastatic adenocarcinomas all corresponded to metastases from patients with a well-documented history of a primary tumor at another location.
  • We found variable positivity with podoplanin in all primary cutaneous neoplasms including spiradenoma (6/6), hidradenoma (2/4), cylindroma (3/3), desmoplastic trichilemmoma (1/1), poorly differentiated squamous cell carcinoma (4/4), sebaceous carcinoma (1/1), basal cell carcinoma (4/10), trichilemmal carcinoma (2/2), eccrine carcinoma (3/3), microcystic adnexal carcinoma (1/1), adnexal carcinoma NOS (1/1), and porocarcinoma (1/1).
  • In contrast, all metastatic carcinomas were negative (0/42) for podoplanin.
  • In regards to p63, all cases of primary cutaneous tumors were positive for p63 (37/37); in contrast, all cutaneous metastatic carcinomas were negative (0/42).
  • Sensitivity, specificity, and positive and negative predictive values of podoplanin and p63 immunoreactivity to separate primary skin neoplasms from metastatic carcinomas were 78.4, 100.0, 100.0 and 84.0% for podoplanin, respectively, and 100.0, 100.0, 100.0 and 100.0% for p63, respectively.
  • The differences in p63 and podoplanin immunohistochemical expression between primary skin tumors and metastatic carcinomas to the skin were statistically significant (p < 0, 0001).
  • The results of our study suggest that the combined expression of p63 and podoplanin are a useful adjunct for the diagnosis of skin tumors in the clinical setting of a questionable metastasis and may be relatively specific for distinguishing primary skin tumors from metastatic carcinomas to the skin.
  • [MeSH-major] Adenocarcinoma / metabolism. Membrane Glycoproteins / metabolism. Membrane Proteins / metabolism. Skin / metabolism. Skin Neoplasms / metabolism
  • [MeSH-minor] Diagnosis, Differential. Humans. Immunohistochemistry

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20377670.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / CKAP4 protein, human; 0 / Membrane Glycoproteins; 0 / Membrane Proteins; 0 / PDPN protein, human
  •  go-up   go-down


43. Donovan DJ, Person DA: Giant eccrine adenocarcinoma of the scalp with intracranial invasion: resection and reconstruction using a vacuum-assisted closure device: technical case report. Neurosurgery; 2006 Apr;58(4 Suppl 2):ONS-E371; discussion ONS-E371
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE AND IMPORTANCE: Carcinoma of the adnexal structures of the skin is a rare malignancy, and is even more unusual in the scalp.
  • We report an unusual case of scalp adnexal carcinoma of eccrine origin that went untreated for years, resulting in a giant tumor with extension through the cranium.
  • CLINICAL PRESENTATION: A 54-year-old woman experienced a large recurrence of her scalp adnexal carcinoma after an incomplete wide local excision, which invaded through the cranium.
  • Another split thickness skin graft was used to provide a cosmetically acceptable outcome.
  • CONCLUSION: Scalp adnexal tumors of eccrine origin rarely metastasize and can be resected for cure with complete removal.
  • The novel use of a vacuum-assisted wound closure device was a very useful adjunct in this situation, and may be beneficial in the reconstruction of other patients with large scalp and cranial defects after neurosurgical procedures.
  • [MeSH-major] Adenocarcinoma / surgery. Bone Neoplasms / surgery. Reconstructive Surgical Procedures / methods. Skin Neoplasms / surgery. Vacuum Curettage
  • [MeSH-minor] Female. Humans. Magnetic Resonance Imaging / methods. Middle Aged. Skin Transplantation / methods. Subdural Effusion / etiology. Subdural Effusion / surgery

  • MedlinePlus Health Information. consumer health - Bone Cancer.
  • MedlinePlus Health Information. consumer health - Plastic and Cosmetic Surgery.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Neurosurgery. 2008 Aug;63(2):E376; author reply E376 [18797336.001]
  • [CommentIn] Neurosurgery. 2008 Aug;63(2):E376; author reply E376 [18797334.001]
  • (PMID = 16575296.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


44. Brandt SM, Swistel AJ, Rosen PP: Secretory carcinoma in the axilla: probable origin from axillary skin appendage glands in a young girl. Am J Surg Pathol; 2009 Jun;33(6):950-3
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Secretory carcinoma in the axilla: probable origin from axillary skin appendage glands in a young girl.
  • Invasive carcinoma in the axilla may arise from skin appendage glands or ectopic breast tissue or it may be a metastasis.
  • Carcinomas of the skin adnexal glands and breast can be difficult to distinguish from each other as they often display the same patterns of growth.
  • Tubular, cribriform, papillary, apocrine, mucinous, and adenoid cystic are histologic types of carcinoma seen in the breast and skin appendage glands.
  • To our knowledge, secretory carcinoma, the most common form of mammary carcinoma in children, has not yet been described as a morphologic pattern of skin adnexal carcinoma, although we cannot exclude the possibility that such a case was reported with a different diagnosis.
  • We report a case of a young girl with secretory carcinoma that seems to have arisen from skin appendage glands in the skin of the axilla in the absence of demonstrable ectopic breast tissue.
  • [MeSH-major] Axilla / pathology. Carcinoma, Skin Appendage / pathology. Skin Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Am J Surg Pathol. 2010 Aug;34(8):1226-7; author reply 1228 [20631609.001]
  • (PMID = 19342945.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


45. Mahalingam M, Srivastava A, Hoang MP: Expression of stem-cell markers (cytokeratin 15 and nestin) in primary adnexal neoplasms-clues to etiopathogenesis. Am J Dermatopathol; 2010 Dec;32(8):774-9
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of stem-cell markers (cytokeratin 15 and nestin) in primary adnexal neoplasms-clues to etiopathogenesis.
  • METHODS: We evaluated expression of follicular stem-cell markers, cytokeratin (CK) 15 and nestin, in 78 benign and 23 malignant adnexal neoplasms.
  • CK15 and nestin expression were noted in 11 of 23 (48%) and 7 of 23 (30%) cases in the malignant group, respectively (6 microcystic adnexal carcinoma, 7 porocarcinoma, and 9 eccrine carcinoma).
  • Except 1, both markers were negative in 4 syringocystadenoma papilliferum, 10 hidradenoma, 1 syringofibroadenoma, 10 syringoma, 1 eccrine adenoma, 8 poroma/dermal duct tumor, 5 eccrine hidrocystoma, and 1 apocrine carcinoma.
  • Reinforcing this and a novel finding of our study is the preferential expression of nestin in myoepithelial cells of these lesions.
  • [MeSH-major] Apocrine Glands / chemistry. Biomarkers, Tumor / analysis. Eccrine Glands / chemistry. Intermediate Filament Proteins / analysis. Keratin-15 / analysis. Neoplasms, Adnexal and Skin Appendage / chemistry. Neoplastic Stem Cells / chemistry. Nerve Tissue Proteins / analysis. Sweat Gland Neoplasms / chemistry
  • [MeSH-minor] Boston. Cell Lineage. Diagnosis, Differential. Humans. Immunohistochemistry. Nestin. Predictive Value of Tests

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20700038.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Intermediate Filament Proteins; 0 / KRT15 protein, human; 0 / Keratin-15; 0 / NES protein, human; 0 / Nerve Tissue Proteins; 0 / Nestin
  •  go-up   go-down


46. Vidal CI, Goldberg M, Burstein DE, Emanuel HJ, Emanuel PO: p63 Immunohistochemistry is a useful adjunct in distinguishing sclerosing cutaneous tumors. Am J Dermatopathol; 2010 May;32(3):257-61
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We aimed to assess the utility of p63 immunohistochemical staining in distinguishing microcystic adnexal carcinoma (MAC) from sclerosing basal cell carcinoma (SBCC) and desmoplastic trichoepithelioma (DTE).
  • Although all adnexal tumors examined demonstrated p63 expression, the pattern of staining was strikingly different in MAC when compared with other tumor types.
  • [MeSH-major] Biomarkers, Tumor / analysis. Carcinoma, Basal Cell / diagnosis. Carcinoma, Skin Appendage / diagnosis. Skin Neoplasms / diagnosis. Trans-Activators / analysis. Tumor Suppressor Proteins / analysis


47. Henning JS: Extramammary Paget's disease of the penis and scrotum. J Drugs Dermatol; 2006 Jul-Aug;5(7):652-4
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extramammary Paget's disease of the penis and scrotum.
  • A biopsy specimen showed extramammary Paget's disease.
  • Twenty years earlier, while living in China in 1983, this patient had a suprapubic skin cancer which was excised, and he received radiation to the region.
  • Extramammary Paget's disease is a rare cutaneous adenocarcinoma of epidermal origin, which is frequently associated with adnexal carcinoma and internal malignant conditions.
  • Clinically, extramammary Paget's disease is characterized by a red, moist, eroded plaque in the anogenital region.
  • Extramammary Paget's disease usually behaves as a slow-growing intraepithelial adenocarcinoma; however, it may become invasive and may metastasize through dermal lymphatics.
  • [MeSH-major] Paget Disease, Extramammary / pathology. Penile Neoplasms / pathology. Scrotum. Skin Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16865871.001).
  • [ISSN] 1545-9616
  • [Journal-full-title] Journal of drugs in dermatology : JDD
  • [ISO-abbreviation] J Drugs Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


48. Li YC, Lu LY, Yang YT, Chang CC, Chen LM: Extramammary Paget's disease of the scrotum associated with hepatocellular carcinoma. J Chin Med Assoc; 2009 Oct;72(10):542-6
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extramammary Paget's disease of the scrotum associated with hepatocellular carcinoma.
  • Extramammary Paget's disease (EMPD) is a rare cutaneous carcinoma of epidermal origin.
  • The diagnosis is frequently delayed, and the disease tends to be associated with an underlying adnexal or internal malignancy.
  • There have been several reports of EMPD associated with carcinoma of the bladder, prostate, kidney, and colon.
  • The association of hepatocellular carcinoma (HCC) with EMPD appears to be exceedingly rare; to our knowledge, it has been reported only once in the English literature.
  • EMPD was diagnosed 1 year after the appearance of an erythematous plaque, and HCC was noted 19 months after the diagnosis of EMPD.
  • From our experience and literature review, in patients with nonspecific skin lesions that are unresponsive to conventional treatment, EMPD should be considered and skin biopsy performed.
  • Long-term follow-up is needed to watch for the appearance of adnexal carcinoma or internal malignancy.
  • [MeSH-major] Carcinoma, Hepatocellular / complications. Genital Neoplasms, Male / etiology. Liver Neoplasms / complications. Paget Disease, Extramammary / etiology. Scrotum / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19837650.001).
  • [ISSN] 1728-7731
  • [Journal-full-title] Journal of the Chinese Medical Association : JCMA
  • [ISO-abbreviation] J Chin Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
  •  go-up   go-down


49. Thosani MK, Marghoob A, Chen CS: Current progress of immunostains in Mohs micrographic surgery: a review. Dermatol Surg; 2008 Dec;34(12):1621-36
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Mohs micrographic surgery is often considered the treatment of choice for a variety of skin malignancies.
  • In recent years, the application of immunostaining techniques has facilitated the successful removal of a number of common and less common cutaneous malignancies, including basal cell carcinoma, squamous cell carcinoma, malignant melanoma, dermatofibrosarcoma protuberans, microcystic adnexal carcinoma, sebaceous carcinoma, atypical fibroxanthoma, extramammary Paget's disease, and even sarcomas.
  • [MeSH-major] Mohs Surgery / methods. Skin Neoplasms / pathology. Skin Neoplasms / surgery. Staining and Labeling / methods

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19018832.001).
  • [ISSN] 1524-4725
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 127
  •  go-up   go-down


50. Pedamallu SB, Murphy J, Boyd D, Martin-Hirsch D, Al-Zwae K: Direct intracranial extension of malignant eccrine spiradenoma of the face. J Clin Med Res; 2009 Aug;1(3):181-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Direct intracranial extension of malignant eccrine spiradenoma of the face.
  • Malignant eccrine spiradenomas are exceedingly rare tumours.
  • We present a case of malignant eccrine spiradenoma of the right side of the face with direct intracranial extension without distant metastasis.
  • Histopathological findings were consistent with malignant eccrine spiradenoma.
  • This is a rare case of facial malignant eccrine spiradenoma with direct intracranial extension with no distant metastasis.
  • KEYWORDS: Eccrine carcinoma; Spiradenoma; Adnexal carcinoma; Malignant eccrine spiradenoma.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 22493654.001).
  • [ISSN] 1918-3003
  • [Journal-full-title] Journal of clinical medicine research
  • [ISO-abbreviation] J Clin Med Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC3318883
  •  go-up   go-down


51. Hall G, Duncan A, Azurdia R, Leonard N: Lymphoepithelioma-like carcinoma of the skin: a case with lymph node metastases at presentation. Am J Dermatopathol; 2006 Jun;28(3):211-5
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lymphoepithelioma-like carcinoma of the skin: a case with lymph node metastases at presentation.
  • We report a case of a primary lymphoepithelioma-like carcinoma (LELC) of the skin.
  • He also had axillary node clearance for metastatic disease.
  • Differential diagnoses included squamous cell carcinoma, adnexal carcinoma, Merkel cell tumors, lymphoepithelial lesions, lymphomas, and skin metastases.
  • The histopathologic and immunohistochemical features were those of a LELC of the skin.
  • Just over 30 cases of primary LELCs arising in the skin have been reported with only 1 documented fatality.
  • [MeSH-major] Carcinoma / pathology. Neovascularization, Pathologic / pathology. Rare Diseases / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Aged. Carcinoma, Merkel Cell / pathology. Diagnosis, Differential. Humans. Lymphatic Metastasis. Lymphoma, B-Cell / pathology. Lymphoma, B-Cell / surgery. Male

  • MedlinePlus Health Information. consumer health - Rare Diseases.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16778488.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


52. Anolik R, Liang C, Wang N, Rosenman K, Pomeranz M, Joe E: Extramammary Paget disease. Dermatol Online J; 2008;14(10):15
Genetic Alliance. consumer health - Paget disease, extramammary.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extramammary Paget disease.
  • A biopsy specimen showed an intra-epidermal neoplasm consistent with extramammary Paget disease (EMPD) based on light microscopy and immunohistochemistry.
  • Patients with EMPD require extensive medical evaluation because of its association with adnexal carcinoma and visceral malignant conditions.
  • Evaluation should include a full body skin and lymph node examination, colonscopy, cystoscopy, and sex-specific studies including pelvic and breast examinations, with imaging for women and prostate examination with prostate specific antigen levels for men.
  • Close monitoring after treatment is important because of the recognized risk of recurrence and malignant conditions.
  • [MeSH-major] Paget Disease, Extramammary / diagnosis. Penile Neoplasms / diagnosis
  • [MeSH-minor] Biomarkers, Tumor / analysis. Biopsy. Diagnostic Errors. Herpes Simplex / diagnosis. Humans. Male. Middle Aged. Skin Ulcer / etiology

  • Genetic Alliance. consumer health - Paget Disease.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19061614.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down


53. De Francesco V, Frattasio A, Pillon B, Stinco G, Scott CA, Trotter D, Patrone P: Carcinosarcoma arising in a patient with multiple cylindromas. Am J Dermatopathol; 2005 Feb;27(1):21-6
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Familial cylindromatosis (Brooke-Spiegler syndrome) is a rare autosomal dominant inherited disease characterized by the development of adnexal tumors, mostly cylindromas, but also trichoepitheliomas and spiradenomas.
  • Malignant tumors may occur, usually with the features of a cylindrocarcinoma.
  • The authors describe the case of a 75-year-old woman with the Brooke-Spiegler syndrome who presented with multiple nodules of the scalp, face, and trunk.
  • In 1997 she underwent surgical excision of the entire forehead and scalp with skin grafting.
  • The lesion was excised and histologic and immunohistochemical evaluation revealed a malignant cutaneous biphasic tumor extending into the subcutis, consisting of a major portion with the features of an adnexal carcinoma and of a minor one of atypical spindle cells.
  • Biphasic malignant skin tumors are rare and only a limited number have been described, none in association with the Brooke-Spiegler syndrome.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Carcinoma, Skin Appendage / pathology. Carcinosarcoma / pathology. Neoplasms, Second Primary / pathology. Neoplastic Syndromes, Hereditary / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Female. Humans. Immunohistochemistry. Skin Transplantation. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15677972.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down


54. Chaudhry IH, Zembowicz A: Adnexal clear cell carcinoma with comedonecrosis: clinicopathologic analysis of 12 cases. Arch Pathol Lab Med; 2007 Nov;131(11):1655-64
MedlinePlus Health Information. consumer health - Acne.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adnexal clear cell carcinoma with comedonecrosis: clinicopathologic analysis of 12 cases.
  • OBJECTIVE: To describe a previously unrecognized, distinctive cutaneous adnexal carcinoma capable of an aggressive clinical course.
  • DESIGN: Clinicopathologic analysis of a series of 12 cases.
  • Histologically, adnexal clear cell carcinoma with comedonecrosis was characterized by dermal proliferation of nests of epithelial cells showing distinctive zonal arrangement.
  • CONCLUSIONS: Adnexal clear cell carcinoma with comedonecrosis appears to be a distinctive adnexal neoplasm that has to be distinguished from more indolent squamous cell and tricholemmal carcinomas.
  • [MeSH-major] Acne Vulgaris / pathology. Carcinoma, Squamous Cell / pathology. Neoplasms, Adnexal and Skin Appendage / pathology
  • [MeSH-minor] Aged. Aged, 80 and over. Carcinoembryonic Antigen / metabolism. Cell Proliferation. Diagnosis, Differential. Epithelial Cells / metabolism. Epithelial Cells / pathology. Female. Humans. Keratin-17 / metabolism. Male. Middle Aged. Mucin-1 / metabolism. Necrosis / metabolism. Necrosis / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Arch Pathol Lab Med. 2011 May;135(5):532; author reply 533 [21526948.001]
  • (PMID = 17979483.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Carcinoembryonic Antigen; 0 / Mucin-1
  •  go-up   go-down


55. Bacchi CE, Silva TR, Zambrano E, Plaza J, Suster S, Luzar B, Lamovec J, Pizzolitto S, Falconieri G: Epithelioid angiosarcoma of the skin: a study of 18 cases with emphasis on its clinicopathologic spectrum and unusual morphologic features. Am J Surg Pathol; 2010 Sep;34(9):1334-43
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epithelioid angiosarcoma of the skin: a study of 18 cases with emphasis on its clinicopathologic spectrum and unusual morphologic features.
  • In elderly patients scalp or facial lesions and cutaneous lesions arising within irradiated breast skin predominated.
  • These cases posed further diagnostic challenges simulating lymphoma, melanoma, lymphoepithelioma-like carcinoma, adnexal carcinoma, and neuroendocrine carcinoma.
  • Of the 9 patients available for follow-up, 5 were alive and apparently well, 2 had recurrent disease, and 2 had died of tumor.
  • [MeSH-major] Epithelioid Cells / pathology. Hemangiosarcoma / pathology. Skin Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20697249.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down


56. Riou-Gotta MO, Fournier E, Danzon A, Pelletier F, Levang J, Mermet I, Blanc D, Humbert P, Aubin F: Rare skin cancer: a population-based cancer registry descriptive study of 151 consecutive cases diagnosed between 1980 and 2004. Acta Oncol; 2009;48(4):605-9
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rare skin cancer: a population-based cancer registry descriptive study of 151 consecutive cases diagnosed between 1980 and 2004.
  • BACKGROUND: There are few epidemiological data available on rare skin cancer, including Merkel cell carcinoma, Paget's disease, adnexal carcinoma, and sarcoma.
  • We conducted this study to investigate the epidemiology of rare skin cancer diagnosed in the department of Doubs from 1980 to 2004.
  • Diagnosis was based on the 3(rd) edition of the International Classification of Diseases for Oncology.
  • Median age for the diagnosed disease was 63 years.
  • Fifty nine cases (39%) were sarcomas, 35 (23%) adnexal carcinomas, 27 (18%) Merkel cell carcinoma and 27 (18%) Paget's disease.
  • The standardized incidence rates were 0.37/100 000 (0.27-0.47) for sarcomas, 0.16 (0.10-0.22) for adnexal tumors, 0.13 (0.08-0.18) for Merkel cell carcinoma, and 0.15 (0.09-0.21) for Paget's disease.
  • CONCLUSIONS: Our results based on a population-based cancer registry showed an increase of the standardized incidence rate for all types of rare skin tumors.
  • [MeSH-major] Skin Neoplasms / epidemiology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Merkel Cell / epidemiology. Child. Female. France / epidemiology. Histiocytoma, Malignant Fibrous / epidemiology. Humans. Incidence. Male. Middle Aged. Neoplasms, Adnexal and Skin Appendage / epidemiology. Rare Diseases / epidemiology. Registries. Retrospective Studies. Sarcoma / epidemiology. Young Adult

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19137462.001).
  • [ISSN] 1651-226X
  • [Journal-full-title] Acta oncologica (Stockholm, Sweden)
  • [ISO-abbreviation] Acta Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Norway
  •  go-up   go-down


57. Carvalho J, Fullen D, Lowe L, Su L, Ma L: The expression of CD23 in cutaneous non-lymphoid neoplasms. J Cutan Pathol; 2007 Sep;34(9):693-8
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CD23 staining was seen in 42% (8/19) of microcystic adnexal carcinoma (MAC), while no staining was observed in tumor cells of desmoplastic trichoepithelioma, morpheaform basal cell carcinoma and syringoma.
  • All mammary and extramammary Paget's disease were labeled with CD23.
  • In comparison, pagetoid Bowen's disease, melanoma in situ and sebaceous carcinoma exhibited negative staining.
  • In addition, CD23 reacted diffusely with cutaneous mucinous eccrine carcinoma in a manner similar to breast or colonic adenocarcinoma.
  • CD23 is a useful addition to the diagnostic immunohistochemical panels for Paget's disease.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Neoplasms, Adnexal and Skin Appendage / metabolism. Receptors, IgE / metabolism. Sweat Gland Neoplasms / metabolism

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17696916.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Receptors, IgE
  •  go-up   go-down


58. Yang WJ, Kim DS, Im YJ, Cho KS, Rha KH, Cho NH, Choi YD: Extramammary Paget's disease of penis and scrotum. Urology; 2005 May;65(5):972-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extramammary Paget's disease of penis and scrotum.
  • OBJECTIVES: To make clear the uncertainty of the clinical outcome of extramammary Paget's disease (EMPD).
  • One patient who had invasion to the subcutaneous tissue died of metastatic EMPD and internal malignancy (renal cell carcinoma) at 17 months after the initial operation.
  • No patient had underlying adnexal carcinoma.
  • [MeSH-major] Genital Neoplasms, Male / surgery. Paget Disease, Extramammary / surgery. Penile Neoplasms / surgery. Scrotum

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15882734.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


59. Alonso T, Sánchez P, González A, Ingelmo J, Ruiz I, Delgado S, Rodríguez MA: [Mohs micrographic surgery: our first 100 patients]. Actas Dermosifiliogr; 2008 May;99(4):275-80
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Cirugía de Mohs: nuestros primeros cien pacientes.
  • In all cases, age, sex, tumor site, tumor type, histological subtype in the case of basal cell carcinoma, size, recurrences, number of Mohs stages, and reconstruction technique were recorded.
  • Of the tumors, 80 % corresponded to basal cell carcinoma, 12.38 % to squamous cell carcinoma, 4.76 % to dermatofibrosarcoma protuberans, 0.95 % to Merkel cell carcinoma, 0.95 % to microcystic adnexal carcinoma, and 0.95 % to lentigo maligna melanoma.
  • After assessing the risk factors independently, we found that the size of the tumor is the risk factor most closely related to grade and subclinical extension in the case of basal cell carcinoma, although similar conclusions cannot be drawn for the other types of tumor studied.
  • [MeSH-major] Mohs Surgery. Skin Neoplasms / surgery
  • [MeSH-minor] Aged. Aged, 80 and over. Carcinoma, Basal Cell / surgery. Female. Humans. Male. Middle Aged

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18394403.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
  •  go-up   go-down


60. Bogner PN, Su LD, Fullen DR: Cluster designation 5 staining of normal and non-lymphoid neoplastic skin. J Cutan Pathol; 2005 Jan;32(1):50-4
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cluster designation 5 staining of normal and non-lymphoid neoplastic skin.
  • RESULTS: Within normal skin, CD5 labeled lymphocytes, apocrine glands, deep dermal eccrine glands, and smooth muscle (weak).
  • The majority of benign and malignant apocrine lesions demonstrated strong focal (36%, n=11)-to-diffuse (64%, n=16) staining.
  • Microcystic adnexal carcinoma demonstrated focal staining of deeper ductal structures (71%, n=7), whereas desmoplastic trichoepithelioma and basal cell carcinoma showed only rare positive cells.
  • All cases of mammary (n=7) and extramammary (n=8) Paget's disease labeled diffusely for CD5.
  • Pagetoid Bowen's disease (n=6), intraepidermal sebaceous carcinoma (n=3), nor melanoma in situ (n=6) showed any CD5 staining.
  • CONCLUSIONS: Immunohistochemical staining for CD5 is extremely useful in the differential diagnosis of pagetoid epidermal lesions and will mark mammary and extramammary Paget's disease, but not pagetoid Bowen's disease, melanoma in situ, or sebaceous carcinoma.
  • [MeSH-major] Antigens, CD5 / metabolism. Skin / metabolism. Skin Neoplasms / enzymology. Skin Neoplasms / metabolism. Staining and Labeling
  • [MeSH-minor] Cell Count. Diagnosis, Differential. Humans. Immunohistochemistry. Paget Disease, Extramammary / diagnosis. Paget's Disease, Mammary / diagnosis. Retrospective Studies

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15660655.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD5
  •  go-up   go-down


61. Nazarian RM, Kapur P, Rakheja D, Piris A, Duncan LM, Mihm MC Jr, Hoang MP: Atypical and malignant hidradenomas: a histological and immunohistochemical study. Mod Pathol; 2009 Apr;22(4):600-10
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Atypical and malignant hidradenomas: a histological and immunohistochemical study.
  • The histological features of atypical hidradenoma are worrisome for increased risk of recurrence and possible malignant potential; however, earlier studies with immunohistochemistry or patient follow-up have not been reported.
  • We compare the histological features and Ki-67, phosphorylated histone H3, epidermal growth factor receptor, and Her2/neu expression profiles of 15 atypical and 15 malignant hidradenomas with those of benign hidradenoma and metastasizing adnexal carcinomas.
  • Significant difference in mean Ki-67% was observed between benign and malignant hidradenomas (P<0.001), benign and metastasizing adnexal carcinomas (0.002), atypical and malignant hidradenomas (P<0.001), and between atypical hidradenomas and metastasizing adnexal carcinomas (0.002).
  • Significant difference in mean phosphorylated histone H3% was observed between benign and malignant hidradenomas (P<0.001), benign and metastasizing adnexal carcinomas (0.003), atypical and malignant hidradenomas (P<0.001), and between atypical hidradenomas and metastasizing adnexal carcinomas (P<0.001).
  • Mean epidermal growth factor receptor total score was significantly different in benign and atypical hidradenoma when compared with that in metastasizing adnexal carcinoma (P=0.014 and 0.019, respectively).
  • Equivocal or 2+ Her2/neu positivity was observed in one hidradenocarcinoma and in two metastasizing adnexal carcinomas.
  • Receiver operating characteristic curve analysis for Ki-67 and phosphorylated histone H3% positivity reveals statistically significant criterion values of >11.425 and >0.7, respectively, for distinguishing malignant hidradenomas from atypical hidradenomas.
  • Despite the presence of some worrisome histological features, the significantly different immunoprofile from the malignant counterpart suggests that atypical hidradenomas are likely to recur but are unlikely to metastasize.
  • A tumor with Ki-67>11% and/or phosphorylated histone H3>0.7% would likely be a malignant rather than an atypical hidradenoma.

  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19252473.001).
  • [ISSN] 1530-0285
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Histones; 0 / Ki-67 Antigen; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; EC 2.7.10.1 / Receptor, ErbB-2
  •  go-up   go-down


62. Minicozzi A, Leopardi F, Segattini C, Pitoni F, Steccanella F, De Manzoni G, Iannucci A, Governa M: [Perianal Paget's disease: five cases report]. G Chir; 2008 Nov-Dec;29(11-12):469-74
MedlinePlus Health Information. consumer health - Anal Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Perianal Paget's disease: five cases report].
  • AIM: Extramammary Paget's disease is a rare neoplastic condition, often associated with a synchronous or metachronous underlying skin or visceral malignancies.
  • The aim of this study was to evaluate retrospectively the results we got in 5 cases of perianal Paget's disease and to revise what literature have reported about this issue.
  • In 3 cases the disease was limited to the epidermidis, in one case with multiple recurrences there was dermal infiltration, and one patient had a low rectal adenocarcinoma with pagetoid phenomenon.
  • Four patients are alive and free from disease and one, who developed a multiple local recurrences, died for heart failure.
  • DISCUSSION: The studies available in literature clearly distinguish between a primary EMPD (intraepidermal/intradermal) and secondary disease which is associated with anorectal adenocarcinomas and is thought to be a pagetoid phenomenon, while few informations can derive from those cases in which the disease is associated with an underlying cutaneous adnexal carcinoma.
  • Disease tend to relapse even after a radical surgery and can have metastatic spread, also in intraepidermal form.
  • CONCLUSIONS: Perianal EMPD is a complex disease, difficult to recognize and the association with synchronous or metachronous malignancies imposes long term clinical and instrumental follow up.
  • [MeSH-major] Anus Neoplasms. Paget Disease, Extramammary

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19068182.001).
  • [ISSN] 0391-9005
  • [Journal-full-title] Il Giornale di chirurgia
  • [ISO-abbreviation] G Chir
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 40
  •  go-up   go-down


63. Kinkor Z, Skálová A, Michal M, Janousek M, Kheck M: [Metastasing and relapsing "low grade" adenosquamous metaplastic breast cancer--is there a really indolent lesion? A description of three cases and review of literature]. Ceska Gynekol; 2005 May;70(3):211-6
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Metastazující a recidivující "low grade" adenoskvamózní metaplastický karcinom prsu--jde skutecnĕ o indolentní lezi? Popis trí prípadů a rozbor literatury.
  • OBJECTIVE: To describe personnel experience with three unusual cases of low-grade adenosquamous carcinoma of the breast.
  • Due to the aggressive course in two cases, the review of the literature does not concentrate on morphology and differential diagnosis only, but discuss overall biology of this lesion too.
  • Histology revealed low-grade adenosquamous metaplastic carcinoma displaying typical biphasic appearance combining regular tubular structures with surrounding storiform, sclerosing fibrous stroma.
  • CONCLUSION: low-grade adenosquamous carcinoma, despite its bland histology, should be understood as regular malignancy prone to frequent recurrences and recognized metastatic potential.
  • It arises in the deep breast tissue and structurally resembles the microcystic adnexal carcinoma of the skin.
  • Low-grade adenosquamous carcinoma, however, has nothing to do with syringomatous adenoma of the nipple, which is a benign tumor of the skin adnexa.
  • Differential diagnosis includes spectrum of non-neoplastic slerosing lesions and above-mentioned phylloid tumor.

  • Genetic Alliance. consumer health - Breast Cancer.
  • MedlinePlus Health Information. consumer health - Breast Cancer.
  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16047925.001).
  • [ISSN] 1210-7832
  • [Journal-full-title] Ceska gynekologie
  • [ISO-abbreviation] Ceska Gynekol
  • [Language] CZE
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Czech Republic
  • [Number-of-references] 12
  •  go-up   go-down


64. Thomas CJ, Wood GC, Marks VJ: Mohs micrographic surgery in the treatment of rare aggressive cutaneous tumors: the Geisinger experience. Dermatol Surg; 2007 Mar;33(3):333-9
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Retrospective chart review of 26,000 cases treated with MMS at the Geisinger Medical Center Department of Dermatology during a 16-year period with the following diagnoses: poorly differentiated squamous cell carcinoma (PDSCC), dermatofibrosarcoma protuberans (DFSP), microcystic adnexal carcinoma (MAC), extramammary Paget's disease (EMPD), Merkel cell carcinoma (MCC), and sebaceous carcinoma (SEB CA).
  • [MeSH-major] Mohs Surgery. Skin Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Merkel Cell / surgery. Carcinoma, Squamous Cell / surgery. Child. Child, Preschool. Dermatofibrosarcoma / surgery. Female. Humans. Infant. Male. Middle Aged. Neoplasm Recurrence, Local / epidemiology. Paget's Disease, Mammary / surgery. Retrospective Studies. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17338692.001).
  • [ISSN] 1076-0512
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


65. Leibovitch I, Huilgol SC, Selva D, Paver R, Richards S: Cutaneous lip tumours treated with Mohs micrographic surgery: clinical features and surgical outcome. Br J Dermatol; 2005 Dec;153(6):1147-52
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: The Australian Mohs micrographic surgery (MMS) database was initiated in 1993 by the Skin and Cancer Foundation Australia (SCFA) with the aim of collecting prospective data, and involved all Mohs surgeons in the country.
  • Basal cell carcinoma (BCC) was diagnosed in 82.3%, squamous cell carcinoma (SCC) in 16.5%, Bowen's disease (BD) in 0.7% and microcystic adnexal carcinoma (MAC) in 0.5% of cases.
  • [MeSH-minor] Adult. Aged. Carcinoma, Basal Cell / pathology. Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Female. Humans. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Recurrence, Local. Prospective Studies. Sex Factors. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16307650.001).
  • [ISSN] 0007-0963
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Multicenter Study
  • [Publication-country] England
  •  go-up   go-down


66. Suwattee P, McClelland MC, Huiras EE, Warshaw EM, Lee PK, Kaye VN, McCalmont TH, Niehans GA: Plaque-type syringoma: two cases misdiagnosed as microcystic adnexal carcinoma. J Cutan Pathol; 2008 Jun;35(6):570-4
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Plaque-type syringoma: two cases misdiagnosed as microcystic adnexal carcinoma.
  • This benign neoplasm may be easily misdiagnosed as microcystic adnexal carcinoma (MAC), potentially resulting in unnecessary surgery with disfiguring consequences.
  • RESULTS AND CONCLUSIONS: Our cases are discussed in the context of histopathologic diagnosis.
  • Detailed histopathologic findings of syringoma, as well as other considerations in the differential diagnosis, are reviewed.
  • [MeSH-major] Carcinoma, Skin Appendage / diagnosis. Cysts / pathology. Diagnostic Errors. Skin Neoplasms / diagnosis. Sweat Gland Neoplasms / diagnosis. Syringoma / diagnosis
  • [MeSH-minor] Aged. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Treatment Outcome

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • Genetic Alliance. consumer health - Syringoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18005172.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  •  go-up   go-down


67. Basile JR, Lin YL: A salivary gland adenocarcinoma mimicking a microcystic adnexal carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Apr;109(4):e28-33
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A salivary gland adenocarcinoma mimicking a microcystic adnexal carcinoma.
  • The microcystic adnexal carcinoma (MAC) is a rare, slow-growing but locally aggressive neoplasm arising in the midface and lips of middle-aged adults.
  • The diagnostic dilemma presented by this lesion is discussed, along with a differential diagnosis and brief review of the literature.
  • [MeSH-major] Adenocarcinoma / pathology. Carcinoma, Skin Appendage / pathology. Lip Neoplasms / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands, Minor / pathology
  • [MeSH-minor] Biopsy. Cell Nucleus / ultrastructure. Cell Proliferation. Connective Tissue / pathology. Cytoplasm / ultrastructure. Diagnosis, Differential. Female. Fibrosis. Humans. Lip / innervation. Middle Aged. Neoplasm Invasiveness. Sclerosis

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2010 Mosby, Inc. All rights reserved.
  • [CommentIn] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011 Sep;112(3):284-6 [21684772.001]
  • (PMID = 20303043.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 14
  •  go-up   go-down


68. Lountzis N, Junkins-Hopkins J, Uberti-Benz M, Elenitsas R: Microcystic adnexal carcinoma arising within a nevus sebaceus. Cutis; 2007 Oct;80(4):352-6
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Microcystic adnexal carcinoma arising within a nevus sebaceus.
  • Nevus sebaceus (NS) is a congenital skin lesion arising on the face and scalp that has been linked to the development of various carcinomas.
  • We describe a case of microcystic adnexal carcinoma (MAC) arising in an NS on the scalp of a 62-year-old man.
  • Excisional skin biopsy and hematoxylin and eosin stains were performed to examine the specimen.
  • This case presents a rare finding of MAC within an NS.


69. Gabillot-Carré M, Weill F, Mamelle G, Kolb F, Boitier F, Petrow P, Ortoli JC, Margulis A, Souteyrand P, Mercier S, Spatz A, Duvillard P, Validire P, Avril MF: Microcystic adnexal carcinoma: report of seven cases including one with lung metastasis. Dermatology; 2006;212(3):221-8
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Microcystic adnexal carcinoma: report of seven cases including one with lung metastasis.
  • BACKGROUND: Microcystic adnexal carcinoma (MAC) is a rare cutaneous neoplasm, with a high rate of local recurrences.
  • In 3 patients, the course of the disease was severe: one of them developed pathologically proven lung metastasis.
  • [MeSH-major] Carcinoma, Skin Appendage / pathology. Facial Neoplasms / pathology. Lung Neoplasms / secondary. Skin Neoplasms / pathology
  • [MeSH-minor] Adult. Carcinoma, Basal Cell / diagnosis. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • MedlinePlus Health Information. consumer health - Lung Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] 2006 S. Karger AG, Basel
  • (PMID = 16549917.001).
  • [ISSN] 1018-8665
  • [Journal-full-title] Dermatology (Basel, Switzerland)
  • [ISO-abbreviation] Dermatology (Basel)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  •  go-up   go-down


70. Leibovitch I, Huilgol SC, Selva D, Lun K, Richards S, Paver R: Microcystic adnexal carcinoma: treatment with Mohs micrographic surgery. J Am Acad Dermatol; 2005 Feb;52(2):295-300
Faculty of 1000. commentaries/discussion - See the articles recommended by F1000Prime's Faculty of more than 8,000 leading experts in Biology and Medicine. (subscription/membership/fee required).

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Microcystic adnexal carcinoma: treatment with Mohs micrographic surgery.
  • BACKGROUND: Microcystic adnexal carcinoma (MAC) is reported to have a high rate of recurrence with standard wide local excision.
  • METHODS: This prospective, multi-center case series included all patients in Australia treated with MMS for MAC, who were monitored by the Skin and Cancer Foundation between 1993 and 2002.
  • In 32.5% of cases the tumor was initially misdiagnosed as basal cell carcinoma or squamous cell carcinoma.
  • [MeSH-major] Carcinoma, Skin Appendage / surgery. Mohs Surgery. Skin Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Australia / epidemiology. Carcinoma, Basal Cell / diagnosis. Carcinoma, Squamous Cell / diagnosis. Child. Databases, Factual. Diagnostic Errors. Female. Follow-Up Studies. Head and Neck Neoplasms / diagnosis. Head and Neck Neoplasms / epidemiology. Head and Neck Neoplasms / surgery. Humans. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Recurrence, Local. Prospective Studies. Retrospective Studies. Treatment Outcome

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15692477.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Review
  • [Publication-country] United States
  • [Number-of-references] 24
  •  go-up   go-down


71. Baxi S, Deb S, Weedon D, Baumann K, Poulsen M: Microcystic adnexal carcinoma of the skin: the role of adjuvant radiotherapy. J Med Imaging Radiat Oncol; 2010 Oct;54(5):477-82
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Microcystic adnexal carcinoma of the skin: the role of adjuvant radiotherapy.
  • INTRODUCTION: Microcystic adnexal carcinoma (MAC) is a rare cutaneous tumour where the role of radiotherapy remains undefined.
  • [MeSH-major] Carcinoma, Skin Appendage / radiotherapy. Head and Neck Neoplasms / radiotherapy. Radiotherapy, Adjuvant. Skin Neoplasms / radiotherapy. Sweat Gland Neoplasms / radiotherapy

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • MedlinePlus Health Information. consumer health - Head and Neck Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] © 2010 The Authors. Journal of Medical Imaging and Radiation Oncology © 2010 The Royal Australian and New Zealand College of Radiologists No claim to original US government works.
  • (PMID = 20958947.001).
  • [ISSN] 1754-9485
  • [Journal-full-title] Journal of medical imaging and radiation oncology
  • [ISO-abbreviation] J Med Imaging Radiat Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
  •  go-up   go-down


72. Ohtsuka H, Nozawa R, Kushida Y: Synchronous microcystic adnexal carcinoma and gastric cancer with review of the literature. J Dermatol; 2005 Jan;32(1):43-7
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Synchronous microcystic adnexal carcinoma and gastric cancer with review of the literature.
  • A microcystic adnexal carcinoma (MAC) on the left lateral chest was synchronously accompanied by both an adenocarcinoma and a granular cell tumor of the stomach in a 70-year-old Japanese male.
  • After a definitive diagnosis was made by an excisional biopsy, a second operation was performed with wider excision, followed by split thickness skin grafting.
  • Three lymph nodes were excised for diagnostic purposes and found to be reactive hyperplasia without metastasis of skin tumor cells.
  • [MeSH-major] Carcinoma, Skin Appendage / diagnosis. Granular Cell Tumor / diagnosis. Neoplasms, Multiple Primary / diagnosis. Skin Neoplasms / diagnosis. Stomach Neoplasms / diagnosis
  • [MeSH-minor] Aged. Diagnosis, Differential. Humans. Male. Thorax

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15841661.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 21
  •  go-up   go-down


73. Leibovitch I, Huilgol SC, Richards S, Paver R, Selva D: Periocular microcystic adnexal carcinoma: management and outcome with Mohs' micrographic surgery. Ophthalmologica; 2006;220(2):109-13
Genetic Alliance. consumer health - Microcystic adnexal carcinoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Periocular microcystic adnexal carcinoma: management and outcome with Mohs' micrographic surgery.
  • PURPOSE: To report a series of patients with periocular microcystic adnexal carcinoma (MAC) treated with Mohs' micrographic surgery (MMS).
  • METHODS: This series included all patients treated with MMS for periocular MAC, who were monitored by the Skin and Cancer Foundation Australia between 1993 and 2002.
  • The tumor was initially misdiagnosed as basal cell carcinoma in 3 patients and squamous cell carcinoma in 1 patient.
  • [MeSH-major] Carcinoma, Skin Appendage / surgery. Eyelid Neoplasms / surgery. Mohs Surgery / methods
  • [MeSH-minor] Diagnosis, Differential. Female. Follow-Up Studies. Humans. Male. Middle Aged. Prospective Studies. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16491033.001).
  • [ISSN] 0030-3755
  • [Journal-full-title] Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde
  • [ISO-abbreviation] Ophthalmologica
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] Switzerland
  •  go-up   go-down


74. Fischer S, Breuninger H, Metzler G, Hoffmann J: Microcystic adnexal carcinoma: an often misdiagnosed, locally aggressive growing skin tumor. J Craniofac Surg; 2005 Jan;16(1):53-8
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Microcystic adnexal carcinoma: an often misdiagnosed, locally aggressive growing skin tumor.
  • Microcystic adnexal carcinoma (MAC) belongs to the spectrum of locally aggressive adnexal carcinomas and most commonly occurs in the head and neck region.
  • The authors report the case of a 78-year-old woman in whom a diagnosis of MAC was made when a tumor on the right cheek recurred for the second time.
  • Previous histopathologic diagnoses were squamous cell carcinoma and desmoplastic trichoepithelioma.
  • The reported case demonstrates the difficulties in diagnosing MAC and indicates that MAC should always be considered in the differential diagnosis of slowly growing tumors in the head and neck region.
  • [MeSH-major] Carcinoma, Skin Appendage / pathology. Facial Neoplasms / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Aged. Carcinoma, Squamous Cell / pathology. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Neoplasm Invasiveness. Neoplasm Recurrence, Local / pathology. Neoplasms, Basal Cell / pathology

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15699645.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


75. Khachemoune A, Olbricht SM, Johnson DS: Microcystic adnexal carcinoma: report of four cases treated with Mohs' micrographic surgical technique. Int J Dermatol; 2005 Jun;44(6):507-12
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Microcystic adnexal carcinoma: report of four cases treated with Mohs' micrographic surgical technique.
  • BACKGROUND: Microcystic adnexal carcinoma (MAC) is a rare and aggressive malignant tumor of the sweat glands.
  • The accumulated data continue to confirm that, if the diagnosis of MAC is made early, and if the anatomic location is accessible to excision by MMS, a favorable outcome can be expected.
  • [MeSH-major] Carcinoma, Skin Appendage / surgery. Facial Neoplasms / surgery. Mohs Surgery. Scalp / surgery. Skin Neoplasms / surgery

  • Genetic Alliance. consumer health - Microcystic adnexal carcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15941444.001).
  • [ISSN] 0011-9059
  • [Journal-full-title] International journal of dermatology
  • [ISO-abbreviation] Int. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 29
  •  go-up   go-down


76. Samaila MO: Adnexal skin tumors in Zaria, Nigeria. Ann Afr Med; 2008 Mar;7(1):6-10

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adnexal skin tumors in Zaria, Nigeria.
  • BACKGROUND: Adnexal skin tumors share many features in common and differentiate along one line.
  • The aim of this report is to review and classify all adnexal tumors seen in a pathology department over a 16-year period.
  • METHOD: A 16-year retrospective analysis of all adnexal skin tumors seen in a large University Teaching Hospital in Nigeria from January 1991- December 2006.
  • RESULTS: Fifty-two adnexal tumors were seen, accounting for 0.9% of all cutaneous tumors seen within the same period.
  • Only two cases had a clinical diagnosis of adnexal tumor.
  • Forty-six lesions (88.5%) were benign and six (11.5%) malignant.
  • CONCLUSION: Adnexal skin tumors have distinct histological patterns which differentiates them from other cutaneous tumors.
  • Malignant adnexal tumors are uncommon in our setting.
  • [MeSH-major] Carcinoma, Skin Appendage / classification. Neoplasms, Adnexal and Skin Appendage / classification

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18702242.001).
  • [ISSN] 1596-3519
  • [Journal-full-title] Annals of African medicine
  • [ISO-abbreviation] Ann Afr Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nigeria
  •  go-up   go-down


77. Marana R, Muzii L, Ferrari S, Catalano GF, Zannoni G, Marana E: Management of adnexal cystic masses with unexpected intracystic vegetations detected during laparoscopy. J Minim Invasive Gynecol; 2005 Nov-Dec;12(6):502-7
MedlinePlus Health Information. consumer health - Ovarian Cysts.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Management of adnexal cystic masses with unexpected intracystic vegetations detected during laparoscopy.
  • STUDY OBJECTIVE: To evaluate a prospective series of consecutive patients with unexpected intracystic vegetations detected during operative laparoscopy for adnexal masses.
  • PATIENTS: Consecutive patients found during surgery to have unexpected intracystic vegetations and treated by operative laparoscopy, out of a total series of 667 patients under 40 years of age with ultrasonographic evidence of an adnexal cystic mass without thick septa, internal wall papillarities, or solid components.
  • Frozen section diagnosis was benign in 32 patients and borderline in 3 patients.
  • Final pathology diagnosis was borderline ovarian tumor in five of the 35 patients (14.3%), and benign in 30 patients (85.7%).
  • No case of invasive carcinoma was diagnosed either at frozen section or at final pathology examination.
  • The patients with borderline tumors are alive with no evidence of disease after a mean follow-up of 60 months.
  • CONCLUSIONS: In the present series, with accurate preoperative selection, the rate of adnexal cysts with unexpected intracystic vegetations was 5%, of which 14% were borderline tumors.
  • The laparoscopic management of these adnexal masses did not adversely affect the prognosis.
  • [MeSH-major] Adnexal Diseases / diagnosis. Cystadenoma / diagnosis. Ovarian Cysts / surgery
  • [MeSH-minor] Abdomen / ultrasonography. Adult. Female. Genital Neoplasms, Female / complications. Genital Neoplasms, Female / diagnosis. Genital Neoplasms, Female / surgery. Humans. Laparoscopy. Prospective Studies. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16337577.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


78. Güerrissi JO, Quiroga JP: Adnexal carcinomas of the head and neck. Indian J Plast Surg; 2008 Jul;41(2):229-34

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adnexal carcinomas of the head and neck.
  • Adnexal carcinomas of the skin are rare and they derive from structures such as sweat glands, sebaceous glands, and hair follicles.
  • Adnexal tumors represent 1-2% of skin cancers.
  • Between 1998 and 2004, eight patients with malignant adnexal tumors of the head and neck were treated in the Plastic Surgery Service in Argerich Hospital in Buenos Aires, Argentina.
  • Four (50%) of them had malignant cylindromas, two (25%) had sebaceous carcinoma, and the other two (25%) syringoid eccrine carcinoma.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Dermatologica. 1980;160(6):361-70 [6248388.001]
  • [Cites] Br J Plast Surg. 1990 Nov;43(6):702-5 [2175228.001]
  • [Cites] Int J Oral Maxillofac Surg. 1996 Jun;25(3):196-8 [8872222.001]
  • [Cites] Ann Plast Surg. 1996 Feb;36(2):194-6 [8919387.001]
  • [Cites] Semin Cutan Med Surg. 1999 Sep;18(3):233-43 [10468043.001]
  • [Cites] Histopathology. 1980 Jul;4(4):445-66 [6253380.001]
  • [Cites] Genet Couns. 2004;15(2):175-82 [15287417.001]
  • (PMID = 19753272.001).
  • [ISSN] 0970-0358
  • [Journal-full-title] Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India
  • [ISO-abbreviation] Indian J Plast Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2740523
  • [Keywords] NOTNLM ; Adnexal carcinomas / adnexal tumors / skin cancer
  •  go-up   go-down


79. Battistella M, Mateus C, Lassau N, Chami L, Boukoucha M, Duvillard P, Cribier B, Robert C: Sunitinib efficacy in the treatment of metastatic skin adnexal carcinomas: report of two patients with hidradenocarcinoma and trichoblastic carcinoma. J Eur Acad Dermatol Venereol; 2010 Feb;24(2):199-203
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sunitinib efficacy in the treatment of metastatic skin adnexal carcinomas: report of two patients with hidradenocarcinoma and trichoblastic carcinoma.
  • BACKGROUND: Adnexal carcinomas are rare and diverse cutaneous tumours.
  • Metastatic adnexal carcinomas are very resistant to conventional chemotherapies.
  • Its use in adnexal carcinomas has never been reported.
  • The second patient had a metastatic malignant hair follicle tumour (trichoblastic carcinoma) and achieved a partial remission with sunitinib, and disease stabilized after 10 months.
  • CONCLUSIONS: Sunitinib was effective in controlling the disease in our two patients.
  • [MeSH-major] Acrospiroma / drug therapy. Adenocarcinoma / drug therapy. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Indoles / therapeutic use. Neoplasm Metastasis. Pyrroles / therapeutic use. Skin Neoplasms / drug therapy

  • Genetic Alliance. consumer health - Hidradenocarcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19522717.001).
  • [ISSN] 1468-3083
  • [Journal-full-title] Journal of the European Academy of Dermatology and Venereology : JEADV
  • [ISO-abbreviation] J Eur Acad Dermatol Venereol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Indoles; 0 / Pyrroles; 0 / sunitinib
  •  go-up   go-down


80. Puri PK, Galan A, Glusac EJ, Cowper SE: Metastatic cutaneous carcinoid tumor mimicking an adnexal poroid neoplasm. J Cutan Pathol; 2008 Jan;35(1):54-7
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastatic cutaneous carcinoid tumor mimicking an adnexal poroid neoplasm.
  • Herein, we report an unusual case of metastatic cutaneous carcinoid tumor mimicking an adnexal poroid neoplasm.
  • METHODS: A 53-year-old male man presented with a neoplasm on the vertex of the scalp, clinically resembling a pigmented basal cell carcinoma.
  • RESULTS: A shave biopsy was suggestive of an apocrine poroma, however, a metastatic carcinoma could not be excluded.
  • After acquiring additional clinical information and the complete excision of the neoplasm, further immunohistochemical stains supported the diagnosis a metastatic carcinoid tumor.
  • [MeSH-major] Adenoma, Sweat Gland / diagnosis. Apocrine Glands / pathology. Carcinoid Tumor / diagnosis. Skin Neoplasms / diagnosis. Sweat Gland Neoplasms / diagnosis
  • [MeSH-minor] Biomarkers, Tumor / analysis. Diagnosis, Differential. Humans. Male. Middle Aged

  • Genetic Alliance. consumer health - Carcinoid Tumor.
  • MedlinePlus Health Information. consumer health - Carcinoid Tumors.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18095995.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down


81. Zhang J, Mironov S, Hricak H, Ishill NM, Moskowitz CS, Soslow RA, Chi DS: Characterization of adnexal masses using feature analysis at contrast-enhanced helical computed tomography. J Comput Assist Tomogr; 2008 Jul-Aug;32(4):533-40
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Characterization of adnexal masses using feature analysis at contrast-enhanced helical computed tomography.
  • OBJECTIVE: To determine the computed tomographic imaging features predictive of adnexal malignancy and evaluate the accuracy of contrast-enhanced helical computed tomography (CT) in the characterization of adnexal masses.
  • For 143 consecutive patients who underwent preoperative contrast-enhanced CT of the abdomen and pelvis and had adnexal masses found at surgical pathology, preoperative contrast-enhanced computed tomographic scans were retrospectively and independently reviewed by 2 radiologists.
  • Receiver operating characteristic analysis was used to assess the value of contrast-enhanced CT in detecting and characterizing adnexal masses.
  • Feature analysis was performed to select the findings with the highest sensitivities and specificities for predicting malignant lesions.
  • RESULTS: At surgical pathology, 234 adnexal masses were found (165 were malignant).
  • Readers 1 and 2 detected 215 and 216 (92%) adnexal masses, respectively.
  • CONCLUSIONS: Contrast-enhanced helical CT is highly accurate in characterizing adnexal masses as malignant.
  • Recognition of the computed tomographic features most often associated with adnexal malignancy will assist in more confident use of this modality and may potentially obviate the need for additional imaging studies before treatment selection.
  • [MeSH-major] Adnexal Diseases / diagnosis. Carcinoma, Papillary / diagnosis. Contrast Media / administration & dosage. Ovarian Neoplasms / diagnosis. Radiographic Image Enhancement / methods. Tomography, Spiral Computed / methods
  • [MeSH-minor] Adnexa Uteri / radiography. Adnexa Uteri / surgery. Adolescent. Adult. Aged. Aged, 80 and over. Diagnosis, Differential. Female. Humans. Middle Aged. Observer Variation. Predictive Value of Tests. ROC Curve. Reproducibility of Results. Retrospective Studies. Sensitivity and Specificity

  • MedlinePlus Health Information. consumer health - Ovarian Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18664838.001).
  • [ISSN] 1532-3145
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
  •  go-up   go-down


82. Wanapirak C, Srisupundit K, Tongsong T: Sonographic morphology scores (SMS) for differentiation between benign and malignant adnexal masses. Asian Pac J Cancer Prev; 2006 Jul-Sep;7(3):407-10
MedlinePlus Health Information. consumer health - Ovarian Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sonographic morphology scores (SMS) for differentiation between benign and malignant adnexal masses.
  • OBJECTIVE: To determine the sensitivity and specificity of a scoring system for distinguishing between benign and malignant adnexal masses and to detect threshold scores for prediction of malignant ovarian tumors.
  • The final diagnosis was based on either pathological or operative findings.
  • MAIN OUTCOME MEASURE: Sensitivity and specificity of the best cut-off score.
  • RESULTS: A score of 5 from the receiver operating characteristic curve was found to be the best cut-off score, giving a sensitivity and a specificity of 85% and 70%, respectively.
  • CONCLUSION: Sonographic morphology scores are useful in distinguishing adnexal malignancies from benign lesions in some selected cases.
  • [MeSH-major] Adnexal Diseases / diagnostic imaging. Ovarian Neoplasms / diagnostic imaging. Ultrasonography, Doppler
  • [MeSH-minor] Adenocarcinoma, Clear Cell / ultrastructure. Adenocarcinoma, Mucinous / ultrastructure. Adolescent. Adult. Aged. Carcinoma, Endometrioid / ultrastructure. Cross-Sectional Studies. Cystadenoma, Serous / ultrastructure. Diagnosis, Differential. Female. Humans. Incidence. Middle Aged. Neoplasm Staging. Predictive Value of Tests. ROC Curve. Risk Factors. Sensitivity and Specificity

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17059332.001).
  • [ISSN] 1513-7368
  • [Journal-full-title] Asian Pacific journal of cancer prevention : APJCP
  • [ISO-abbreviation] Asian Pac. J. Cancer Prev.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Thailand
  •  go-up   go-down


83. Auw-Hädrich C, Göbel N, Illerhaus G: [Infectious agents in ocular adnexal tumours]. Klin Monbl Augenheilkd; 2010 Jul;227(7):530-7
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Infectious agents in ocular adnexal tumours].
  • In recent years, infectious agents have been increasingly recognised as an important pathogenetic factor for various malignant tumours of the ocular adnexa.
  • Ocular adnexal lymphoma (OAL), especially extranodal marginal cell lymphoma, is associated with Chlamydophila psittaci and Helicobacter pylori in certain geographic regions.
  • Bacteria seem to induce reactive lymphoid proliferation, while viruses directly infect the lymphoid cells, affecting the cell cycle and suppressing apoptosis, with subsequent malignant transformation.
  • HIV positivity also seems to aid the development of CIN and conjunctival squamous cell carcinoma, with an increasing number of cases during recent years.
  • Kaposi sarcoma rarely occurs at the ocular adnexa in HIV-positive individuals and seems to be associated with Kaposi sarcoma-associated Herpes virus (KSHV) or HHV8.

  • MedlinePlus Health Information. consumer health - Eye Cancer.
  • HIV InSite. treatment guidelines - Ophthalmic Manifestations of HIV .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Georg Thieme Verlag KG Stuttgart, New York.
  • (PMID = 20535664.001).
  • [ISSN] 1439-3999
  • [Journal-full-title] Klinische Monatsblätter für Augenheilkunde
  • [ISO-abbreviation] Klin Monbl Augenheilkd
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  •  go-up   go-down


84. Ntomouchtsis A, Vahtsevanos K, Patrikidou A, Andreadis C, Tsobanidou C, Antoniades K: Adnexal skin carcinomas of the face. J Craniofac Surg; 2009 Jan;20(1):134-7
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adnexal skin carcinomas of the face.
  • Skin adnexal neoplasms are rare tumors, and knowledge on their exact histological development and pathogenesis remains fragmented.
  • Their diagnosis and management are frequently troublesome, especially for malignant tumors.
  • We present a retrospective case series of malignant appendageal tumors of the face.
  • Records of patients with histologically confirmed adnexal skin carcinoma managed at a single department during the period 1995 to 2004 were reviewed.
  • Patient biodata, surgical management, and main outcome measures such as locoregional recurrence, distant metastasis, and disease-free and overall survival were recorded.Eleven patients were identified from record analysis.
  • Nine of 11 patients were alive and free of local and/or regional disease on final follow-up.
  • Two patients died of causes unrelated to the disease.
  • Clinical and histological features, tumor biological behavior, diagnostic difficulties, and recommended management are discussed.In conclusion, adnexal skin tumors should be considered in the differential diagnosis of skin tumors, particularly in view of their more sinister prognosis compared with other nonmelanoma skin tumors.
  • [MeSH-major] Carcinoma, Skin Appendage / surgery. Facial Neoplasms / surgery. Skin Neoplasms / surgery
  • [MeSH-minor] Aged. Aged, 80 and over. Carcinoma, Basal Cell / diagnosis. Carcinoma, Squamous Cell / diagnosis. Cohort Studies. Diagnosis, Differential. Disease-Free Survival. Eyelid Neoplasms / surgery. Female. Follow-Up Studies. Humans. Lymphatic Metastasis / pathology. Male. Middle Aged. Neck Dissection. Neoplasm Recurrence, Local / pathology. Neoplasms, Second Primary / pathology. Nose Neoplasms / surgery. Retrospective Studies. Surgical Flaps. Survival Rate. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19165010.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


85. Shwayder JM: Pelvic pain, adnexal masses, and ultrasound. Semin Reprod Med; 2008 May;26(3):252-65
MedlinePlus Health Information. consumer health - Pelvic Pain.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pelvic pain, adnexal masses, and ultrasound.
  • This section reviews the use of various ultrasound modalities in evaluating adnexal masses and associated pelvic pain.
  • Morphologic assessment with two-dimensional (2-D) ultrasound is the foundation for adnexal evaluation.
  • The ultrasound morphology of common ovarian and adnexal masses is reviewed.
  • This section reviews the application of 2-D morphology, Doppler analysis, 3-D morphology, rendering and vascular assessment, and the use of contrast agents in the ultrasound evaluation of patients with adnexal masses and pelvic pain.
  • [MeSH-major] Adnexa Uteri / ultrasonography. Adnexal Diseases / ultrasonography. Pelvic Pain / ultrasonography
  • [MeSH-minor] Abscess / ultrasonography. Carcinoma / ultrasonography. Corpus Luteum / ultrasonography. Diagnostic Techniques, Obstetrical and Gynecological / trends. Endometriosis / ultrasonography. Fallopian Tubes / pathology. Fallopian Tubes / ultrasonography. Female. Humans. Inflammation / ultrasonography. Ovarian Cysts / ultrasonography. Ovarian Neoplasms / etiology. Ovarian Neoplasms / ultrasonography. Risk Factors. Teratoma / ultrasonography

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18504700.001).
  • [ISSN] 1526-8004
  • [Journal-full-title] Seminars in reproductive medicine
  • [ISO-abbreviation] Semin. Reprod. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 42
  •  go-up   go-down


86. Corbalán-Vélez R, Ruiz-Macia JA, Brufau C, López-Lozano JM, Martínez-Barba E, Carapeto FJ: [Clear cells in cutaneous squamous cell carcinoma]. Actas Dermosifiliogr; 2009 May;100(4):307-16
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clear cells in cutaneous squamous cell carcinoma].
  • [Transliterated title] Las células claras en el carcinoma espinocelular cutáneo.
  • INTRODUCTION: Although few cases of squamous cell carcinoma (SCC) with clear cells have been published, we believe that these cells are often present in SCC.
  • Various immunohistochemical techniques (immunoperoxidase method) were used to determine whether adnexal differentiation was present.
  • Advanced or established SCCs and SCCs associated with Bowen disease contained a larger proportion of clear cells.
  • We defined 2 histological patterns: a) clear cells around the keratin pearls of SCCs arising from pre-existing actinic keratosis and with indirect signs of human papilloma virus infection in hair follicles; and b) clear cells that simulate adnexal differentiation in lesions arising on pre-existing Bowen disease lesions.
  • There were also 19 carcinomas with true adnexal differentiation.
  • The presence of clear cells is suggestive of adnexal differentiation; however, in the majority of cases, their presence is due to infiltration of normal adnexal structures by the cells of pagetoid Bowen disease.
  • True adnexal differentiation exists only in a small percentage of cases (7.6 % in our study).
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Skin Neoplasms / pathology

  • Genetic Alliance. consumer health - Carcinoma, Squamous Cell.
  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19463234.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
  •  go-up   go-down


87. Smith KM, Scase TJ, Miller JL, Donaldson D, Sansom J: Expression of cyclooxygenase-2 by equine ocular and adnexal squamous cell carcinomas. Vet Ophthalmol; 2008 Sep;11 Suppl 1:8-14
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of cyclooxygenase-2 by equine ocular and adnexal squamous cell carcinomas.
  • OBJECTIVE: To investigate whether cyclooxygenase-2 (COX-2) is expressed by equine ocular and adnexal squamous cell carcinomas (SCC).
  • METHODS: Forty-three samples of histologically confirmed cases of ocular SCC or carcinoma in situ (CIS) from 34 horses presented to the Animal Health Trust between 1992 and 2004 were subjected to a standard, two-layered, indirect immunohistochemical method using a rabbit polyclonal antihuman COX-2 antibody.
  • On the basis of this study, it is unlikely that anti-COX-2 therapy would be of benefit in the treatment of equine ocular and adnexal SCC.
  • [MeSH-major] Carcinoma in Situ / veterinary. Carcinoma, Squamous Cell / veterinary. Cyclooxygenase 2 / metabolism. Eye Neoplasms / veterinary. Horse Diseases / enzymology

  • MedlinePlus Health Information. consumer health - Eye Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19046264.001).
  • [ISSN] 1463-5224
  • [Journal-full-title] Veterinary ophthalmology
  • [ISO-abbreviation] Vet Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] EC 1.14.99.1 / Cyclooxygenase 2
  •  go-up   go-down


88. Verma V, Shen D, Sieving PC, Chan CC: The role of infectious agents in the etiology of ocular adnexal neoplasia. Surv Ophthalmol; 2008 Jul-Aug;53(4):312-31
HIV InSite. treatment guidelines - Human Herpesvirus-8 .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The role of infectious agents in the etiology of ocular adnexal neoplasia.
  • Given the fact that infectious agents contribute to around 18% of human cancers worldwide, it would seem prudent to explore their role in neoplasms of the ocular adnexa: primary malignancies of the conjunctiva, lacrimal glands, eyelids, and orbit.
  • By elucidating the mechanisms by which infectious agents contribute to oncogenesis, the management, treatment, and prevention of these neoplasms may one day parallel what is already in place for cancers such as cervical cancer, hepatocellular carcinoma, gastric mucosa-associated lymphoid tissue lymphoma and gastric adenocarcinoma.
  • Unlike other malignancies for which large epidemiological studies are available, analyzing ocular adnexal neoplasms is challenging as they are relatively rare.
  • This review discusses the pathogenetic role of several microorganisms in different ocular adnexal malignancies, including human papilloma virus in conjunctival papilloma and squamous cell carcinoma, human immunodeficiency virus in conjunctival squamous carcinoma, Kaposi sarcoma-associated herpes virus or human herpes simplex virus-8 (KSHV/HHV-8) in conjunctival Kaposi sarcoma, Helicobacter pylori (H. pylori,), Chlamydia, and hepatitis C virus in ocular adnexal mucosa-associated lymphoid tissue lymphomas.
  • Unlike cervical cancer where a single infectious agent, human papilloma virus, is found in greater than 99% of lesions, multiple organisms may play a role in the etiology of certain ocular adnexal neoplasms by acting through similar mechanisms of oncogenesis, including chronic antigenic stimulation and the action of infectious oncogenes.
  • However, similar to other human malignancies, ultimately the role of infectious agents in ocular adnexal neoplasms is most likely as a cofactor to genetic and environmental risk factors.
  • [MeSH-minor] Alphapapillomavirus / isolation & purification. Alphapapillomavirus / physiology. Carcinoma, Squamous Cell / virology. Chlamydophila psittaci / isolation & purification. Chlamydophila psittaci / physiology. Conjunctival Neoplasms / microbiology. Conjunctival Neoplasms / virology. Eyelid Neoplasms / microbiology. Eyelid Neoplasms / virology. HIV-1 / isolation & purification. HIV-1 / physiology. Helicobacter pylori / isolation & purification. Helicobacter pylori / physiology. Hepacivirus / isolation & purification. Hepacivirus / physiology. Herpesvirus 8, Human / isolation & purification. Herpesvirus 8, Human / physiology. Humans. Lacrimal Apparatus Diseases / microbiology. Lacrimal Apparatus Diseases / virology. Lymphoma, B-Cell, Marginal Zone / virology. Orbital Neoplasms / microbiology. Orbital Neoplasms / virology. Sarcoma, Kaposi / virology

  • MedlinePlus Health Information. consumer health - Eye Cancer.
  • HIV InSite. treatment guidelines - Ophthalmic Manifestations of HIV .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Acta Ophthalmol Scand. 2000 Dec;78(6):663-6 [11167228.001]
  • [Cites] J Virol. 2001 Feb;75(4):1857-63 [11160684.001]
  • [Cites] Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):1218-23 [11158620.001]
  • [Cites] Ophthalmology. 2001 Mar;108(3):559-62 [11237911.001]
  • [Cites] JAMA. 2001 Apr 4;285(13):1736-45 [11277828.001]
  • [Cites] AIDS. 2001 Mar 30;15(5):629-33 [11317001.001]
  • [Cites] Ophthalmology. 2001 May;108(5):979-84 [11320031.001]
  • [Cites] Br J Cancer. 2002 Jul 29;87(3):301-8 [12177799.001]
  • [Cites] Cornea. 2002 Nov;21(8):838-9 [12410049.001]
  • [Cites] Leuk Lymphoma. 2002 Oct;43(10):1975-7 [12481895.001]
  • [Cites] Cornea. 2003 Jan;22(1):1-4 [12502938.001]
  • [Cites] N Engl J Med. 2003 Feb 6;348(6):489-90 [12571255.001]
  • [Cites] Arch Ophthalmol. 2003 Feb;121(2):280-2 [12583801.001]
  • [Cites] Carcinogenesis. 2003 Feb;24(2):159-69 [12584163.001]
  • [Cites] Ophthalmologe. 2003 Feb;100(2):142-4 [12589459.001]
  • [Cites] Cornea. 2003 Mar;22(2):135-7 [12605048.001]
  • [Cites] Acta Ophthalmol Scand. 2003 Apr;81(2):193-6 [12752062.001]
  • [Cites] Oncogene. 2003 May 29;22(22):3371-85 [12776188.001]
  • [Cites] Arch Soc Esp Oftalmol. 2003 May;78(5):265-71 [12789630.001]
  • [Cites] J Natl Cancer Inst Monogr. 2003;(31):57-65 [12807947.001]
  • [Cites] Hematol Oncol Clin North Am. 2003 Jun;17(3):673-96, v [12852650.001]
  • [Cites] Acta Ophthalmol Scand. 2003 Aug;81(4):411-3 [12859274.001]
  • [Cites] Arch Ophthalmol. 2003 Jul;121(7):1052-3 [12860816.001]
  • [Cites] J Med Microbiol. 2003 Aug;52(Pt 8):721-6 [12867569.001]
  • [Cites] Lancet. 2003 Jul 26;362(9380):305-15 [12892963.001]
  • [Cites] Cancer. 2003 Aug 15;98(4):865-71 [12910532.001]
  • [Cites] Ann Oncol. 2003 Sep;14(9):1341-5 [12954572.001]
  • [Cites] Cent Afr J Med. 2003 Jan-Feb;49(1-2):1-4 [14562592.001]
  • [Cites] Ophthalmology. 2004 Sep;111(9):1747-54 [15350332.001]
  • [Cites] Histol Histopathol. 2004 Oct;19(4):1219-26 [15375765.001]
  • [Cites] Cancer. 1972 Jan;29(1):252-60 [5007387.001]
  • [Cites] N Engl J Med. 1978 Nov 30;299(22):1215-20 [309554.001]
  • [Cites] Am J Ophthalmol. 1982 Apr;93(4):393-402 [6280503.001]
  • [Cites] Ann Ophthalmol. 1982 May;14(5):497-9 [7114684.001]
  • [Cites] Cancer. 1983 Oct 15;52(8):1410-6 [6193858.001]
  • [Cites] Am J Ophthalmol. 1983 Nov;96(5):670-4 [6314814.001]
  • [Cites] Ophthalmology. 1984 Sep;91(9):1092-9 [6093020.001]
  • [Cites] Graefes Arch Clin Exp Ophthalmol. 1985;223(3):164-7 [2993107.001]
  • [Cites] Anticancer Res. 1985 Sep-Oct;5(5):485-98 [3904595.001]
  • [Cites] Ophthalmology. 1986 Feb;93(2):176-83 [3951824.001]
  • [Cites] Arch Ophthalmol. 1986 Dec;104(12):1801-5 [3024607.001]
  • [Cites] Arch Ophthalmol. 1986 Dec;104(12):1814-5 [3024608.001]
  • [Cites] Am J Ophthalmol. 1987 Mar 15;103(3 Pt 1):294-301 [3030111.001]
  • [Cites] J Natl Cancer Inst. 1987 Oct;79(4):671-7 [2821311.001]
  • [Cites] Hum Pathol. 1987 Nov;18(11):1115-9 [2824322.001]
  • [Cites] Hum Pathol. 1988 Nov;19(11):1315-26 [3141260.001]
  • [Cites] N Engl J Med. 1989 Jun 1;320(22):1442-6 [2541337.001]
  • [Cites] Lancet. 1990 Jan 20;335(8682):123-8 [1967430.001]
  • [Cites] N Engl J Med. 1991 Oct 17;325(16):1127-31 [1891020.001]
  • [Cites] Nat Med. 1995 Dec;1(12):1274-8 [7489408.001]
  • [Cites] CA Cancer J Clin. 1996 Jan-Feb;46(1):5-27 [8548526.001]
  • [Cites] J Clin Pathol. 1995 Dec;48(12):1106-10 [8567996.001]
  • [Cites] Ophthalmology. 1996 Apr;103(4):631-5 [8618763.001]
  • [Cites] Lancet. 1996 May 25;347(9013):1450-1 [8676629.001]
  • [Cites] Am J Pathol. 1996 Jun;148(6):2009-16 [8669485.001]
  • [Cites] Nat Med. 1996 Aug;2(8):918-24 [8705863.001]
  • [Cites] Br J Ophthalmol. 1999 Jun;83(6):742-7 [10340987.001]
  • [Cites] J Natl Cancer Inst. 1999 Oct 20;91(20):1725-33 [10528022.001]
  • [Cites] Sex Transm Infect. 1999 Oct;75(5):317-9 [10616355.001]
  • [Cites] AIDS. 1999 Dec 24;13(18):2583-8 [10630528.001]
  • [Cites] J Clin Pathol. 1999 Aug;52(8):569-73 [10645225.001]
  • [Cites] Br J Ophthalmol. 2000 Mar;84(3):268-72 [10684836.001]
  • [Cites] CA Cancer J Clin. 2000 Jan-Feb;50(1):7-33 [10735013.001]
  • [Cites] Invest Ophthalmol Vis Sci. 2000 May;41(6):1270-9 [10798640.001]
  • [Cites] J Immunol. 2000 May 15;164(10):5522-9 [10799921.001]
  • [Cites] Nat Med. 2000 May;6(5):536-42 [10802709.001]
  • [Cites] J Biomed Sci. 2000 Sep-Oct;7(5):341-56 [10971133.001]
  • [Cites] J Med Virol. 2000 Oct;62(2):251-8 [11002256.001]
  • [Cites] Arch Ophthalmol. 1997 Nov;115(11):1464-6 [9366682.001]
  • [Cites] Gastroenterology. 1997 Dec;113(6):1848-57 [9394724.001]
  • [Cites] Gastroenterology. 1997 Dec;113(6 Suppl):S61-4 [9394762.001]
  • [Cites] Ophthalmology. 1998 Jan;105(1):185-90 [9442797.001]
  • [Cites] N Engl J Med. 1998 Feb 12;338(7):423-8 [9459645.001]
  • [Cites] Am J Respir Crit Care Med. 1998 Feb;157(2):458-63 [9476858.001]
  • [Cites] Proc Natl Acad Sci U S A. 1998 Mar 3;95(5):2290-5 [9482878.001]
  • [Cites] Br J Ophthalmol. 1997 Nov;81(11):1019-20 [9505833.001]
  • [Cites] Annu Rev Med. 1998;49:289-99 [9509264.001]
  • [Cites] N Engl J Med. 1998 Apr 2;338(14):948-54 [9521982.001]
  • [Cites] Sex Transm Infect. 1998 Feb;74(1):32-4 [9634298.001]
  • [Cites] J Natl Cancer Inst Monogr. 1998;(23):65-71 [9709306.001]
  • [Cites] Bull Soc Belge Ophtalmol. 1998;268:135-41 [9810095.001]
  • [Cites] AIDS. 1998 Oct 22;12(15):2067-72 [9814876.001]
  • [Cites] Invest Ophthalmol Vis Sci. 1999 Mar;40(3):555-62 [10067957.001]
  • [Cites] Gastroenterology. 1999 Apr;116(4):823-30 [10092304.001]
  • [Cites] Ophthalmology. 1999 Apr;106(4):757-60 [10201599.001]
  • [Cites] Br J Ophthalmol. 1999 Jan;83(1):98-103 [10209445.001]
  • [Cites] J Reprod Immunol. 1998 Dec;41(1-2):149-60 [10213307.001]
  • [Cites] J Vet Intern Med. 1999 May-Jun;13(3):153-62 [10357102.001]
  • [Cites] Cornea. 1999 Jul;18(4):495-7 [10422866.001]
  • [Cites] J Pathol. 1999 Sep;189(1):12-9 [10451482.001]
  • [Cites] BMJ. 1999 Aug 21;319(7208):505-8 [10454408.001]
  • [Cites] Cornea. 2001 May;20(4):427-9 [11333335.001]
  • [Cites] Br J Ophthalmol. 2001 Jul;85(7):785-7 [11423448.001]
  • [Cites] Eur J Cancer. 2001 Jul;37(10):1251-69 [11423257.001]
  • [Cites] Mod Pathol. 2001 Jul;14(7):641-9 [11454995.001]
  • [Cites] Dermatology. 2001;203(1):19-23 [11549794.001]
  • [Cites] CA Cancer J Clin. 2001 Jan-Feb;51(1):15-36 [11577478.001]
  • [Cites] Invest Ophthalmol Vis Sci. 2001 Oct;42(11):2450-7 [11581182.001]
  • [Cites] Lancet. 2001 Sep 22;358(9286):958-65 [11583749.001]
  • [Cites] Ann N Y Acad Sci. 2001 Sep;941:69-85 [11594584.001]
  • [Cites] JAMA. 2002 Jan 9;287(2):221-5 [11779265.001]
  • [Cites] Curr Opin Immunol. 2002 Feb;14(1):111-6 [11790540.001]
  • [Cites] Br J Ophthalmol. 2002 Feb;86(2):168-73 [11815342.001]
  • [Cites] Arch Ophthalmol. 2002 Feb;120(2):202-4 [11831924.001]
  • [Cites] Oncogene. 2002 Feb 14;21(8):1251-62 [11850845.001]
  • [Cites] Can J Ophthalmol. 2002 Feb;37(1):14-9; discussion 19-20 [11865953.001]
  • [Cites] Ophthalmology. 2002 Mar;109(3):542-7 [11874759.001]
  • [Cites] Adv Cancer Res. 2002;84:231-76 [11883529.001]
  • [Cites] Am J Clin Pathol. 2002 Mar;117(3):429-36 [11888082.001]
  • [Cites] J Clin Pathol. 2002 Apr;55(4):244-65 [11919208.001]
  • [Cites] Am J Ophthalmol. 2002 May;133(5):601-6 [11992855.001]
  • [Cites] Oncogene. 2002 Jun 6;21(25):3949-60 [12037677.001]
  • [Cites] Am J Ophthalmol. 2002 Aug;134(2):268-70 [12140037.001]
  • [Cites] J Virol. 2005 Dec;79(24):15027-37 [16306573.001]
  • [Cites] Ophthalmologe. 2005 Dec;102(12):1204-6 [15657692.001]
  • [Cites] Ann Oncol. 2006 Jan;17(1):135-40 [16236754.001]
  • [Cites] J Virol. 2006 Jan;80(2):697-709 [16378973.001]
  • [Cites] Blood. 2006 Jan 15;107(2):467-72 [16166588.001]
  • [Cites] Ophthalmologe. 2003 Oct;100(10):808-14 [14618353.001]
  • [Cites] Gut. 2004 Jan;53(1):34-7 [14684573.001]
  • [Cites] J Pathol. 2004 Jan;202(1):23-33 [14694518.001]
  • [Cites] Oral Oncol. 2004 Feb;40(2):120-30 [14693234.001]
  • [Cites] Curr Hematol Rep. 2004 Jan;3(1):11-6 [14695844.001]
  • [Cites] Surv Ophthalmol. 2004 Jan-Feb;49(1):3-24 [14711437.001]
  • [Cites] Gastroenterology. 2003 Dec;125(6):1723-32 [14724825.001]
  • [Cites] CA Cancer J Clin. 2004 Jan-Feb;54(1):8-29 [14974761.001]
  • [Cites] J Virol. 2004 Apr;78(8):4063-73 [15047823.001]
  • [Cites] J Clin Microbiol. 2004 Apr;42(4):1648-51 [15071020.001]
  • [Cites] J Natl Cancer Inst. 2004 Apr 21;96(8):586-94 [15100336.001]
  • [Cites] Ophthalmology. 2004 Jun;111(6):1233-7 [15177977.001]
  • [Cites] Croat Med J. 2004 Jun;45(3):328-32 [15185428.001]
  • [Cites] Eur J Haematol. 2004 Oct;73(4):258-62 [15347312.001]
  • [Cites] Klin Oczna. 2005;107(7-9):475-8 [16417001.001]
  • [Cites] Br J Haematol. 2006 Mar;132(5):651-2 [16445841.001]
  • [Cites] Jpn J Ophthalmol. 2006 Jan-Feb;50(1):7-11 [16453181.001]
  • [Cites] Ann Oncol. 2006 Mar;17(3):484-7 [16500916.001]
  • [Cites] Int J Surg Pathol. 2006 Jan;14(1):85-8 [16501843.001]
  • [Cites] Hematol Oncol. 2006 Mar;24(1):33-7 [16385613.001]
  • [Cites] J Natl Cancer Inst. 2006 Mar 1;98(5):365-6 [16507837.001]
  • [Cites] Virchows Arch. 2006 Mar;448(3):301-5 [16328355.001]
  • [Cites] Leuk Res. 2006 May;30(5):547-51 [16246419.001]
  • [Cites] Int J Cancer. 2006 Jun 15;118(12):3030-44 [16404738.001]
  • [Cites] J Infect Dis. 2006 May 1;193(9):1250-7 [16586362.001]
  • [Cites] Virchows Arch. 2006 Apr;448(4):506-16 [16323006.001]
  • [Cites] Blood. 2006 Apr 15;107(8):3034-44 [16397126.001]
  • [Cites] Am J Gastroenterol. 2006 Apr;101(4):714-20 [16635219.001]
  • [Cites] Ann Oncol. 2006 May;17(5):769-72 [16524978.001]
  • [Cites] Cornea. 2006 May;25(4):490-2 [16670494.001]
  • [Cites] J Mol Histol. 2005 Sep;36(6-7):401-12 [16402152.001]
  • [Cites] Eur J Ophthalmol. 2006 May-Jun;16(3):473-7 [16761254.001]
  • [Cites] Am J Ophthalmol. 2006 Jun;141(6):1162-3 [16765702.001]
  • [Cites] Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9220-5 [16751281.001]
  • [Cites] Br J Ophthalmol. 2006 Jul;90(7):819-22 [16672325.001]
  • [Cites] J Pathol. 2006 Jul;209(3):344-51 [16583361.001]
  • [Cites] Ann Oncol. 2006 Jun;17 Suppl 8:viii15-viii23 [16801335.001]
  • [Cites] Lancet. 1991 Nov 9;338(8776):1175-6 [1682595.001]
  • [Cites] Invest Ophthalmol Vis Sci. 1992 Jan;33(1):184-9 [1309728.001]
  • [Cites] Br J Ophthalmol. 1992 Jan;76(1):47-8 [1739692.001]
  • [Cites] Lancet. 1992 Mar 14;339(8794):632-5 [1347337.001]
  • [Cites] J Virol. 1992 Apr;66(4):2125-34 [1312623.001]
  • [Cites] Acta Ophthalmol (Copenh). 1992 Apr;70(2):248-54 [1319099.001]
  • [Cites] Adv Exp Med Biol. 1992;321:45-9; discussion 51 [1333167.001]
  • [Cites] Ophthalmology. 1993 Apr;100(4):569-73 [8386822.001]
  • [Cites] N Engl J Med. 1994 May 5;330(18):1267-71 [8145781.001]
  • [Cites] Cancer. 1994 May 1;73(9):2395-9 [8168043.001]
  • [Cites] Radiother Oncol. 1994 Mar;30(3):263-6 [7516086.001]
  • [Cites] Am J Ophthalmol. 1994 Oct 15;118(4):463-7 [7943124.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1994 Dec 1;30(5):1207-11 [7525519.001]
  • [Cites] J Pathol. 1994 Sep;174(1):33-7 [7965401.001]
  • [Cites] Science. 1994 Dec 16;266(5192):1865-9 [7997879.001]
  • [Cites] Lancet. 1995 Mar 18;345(8951):695-6 [7885126.001]
  • [Cites] Lancet. 1995 Mar 25;345(8952):761-2 [7891488.001]
  • [Cites] Br J Ophthalmol. 1995 Apr;79(4):392-3 [7742294.001]
  • [Cites] Lancet. 1995 Jun 24;345(8965):1591-4 [7783535.001]
  • [Cites] J Natl Cancer Inst. 1995 Jun 7;87(11):796-802 [7791229.001]
  • [Cites] Arch Ophthalmol. 1995 Aug;113(8):978 [7639671.001]
  • [Cites] Nat Med. 1995 Jul;1(7):707-8 [7585156.001]
  • [Cites] Cancer Lett. 2006 Jul 28;239(1):98-102 [16143449.001]
  • [Cites] J Natl Cancer Inst. 2006 Jul 5;98(13):936-9 [16818858.001]
  • [Cites] Mod Pathol. 2006 Aug;19(8):1055-67 [16648871.001]
  • [Cites] East Afr Med J. 2006 May;83(5):267-70 [16866221.001]
  • [Cites] Ophthalmic Epidemiol. 2006 Aug;13(4):275-9 [16877286.001]
  • [Cites] Curr Opin Oncol. 2006 Sep;18(5):479-86 [16894296.001]
  • [Cites] Clin Cancer Res. 2006 Aug 1;12(15):4491-8 [16899594.001]
  • [Cites] Leuk Res. 2006 Oct;30(10):1305-7 [16420962.001]
  • [Cites] Viral Immunol. 2006 Summer;19(3):468-80 [16987065.001]
  • [Cites] J Natl Cancer Inst. 2006 Oct 4;98(19):1375-82 [17018784.001]
  • [Cites] J Med Microbiol. 2006 Nov;55(Pt 11):1571-5 [17030918.001]
  • [Cites] Ann Oncol. 2006 Nov;17(11):1721-2 [16760269.001]
  • [Cites] Cancer Res. 2006 Dec 1;66(23):11120-4 [17145854.001]
  • [Cites] Rev Med Interne. 2007 Jan;28(1):22-7 [17070619.001]
  • [Cites] Am J Surg Pathol. 2007 Feb;31(2):170-84 [17255761.001]
  • [Cites] Clin Pharmacol Ther. 2007 Feb;81(2):259-64 [17259949.001]
  • [Cites] Ann Oncol. 2007 Feb;18(2):400-1; author reply 401-3 [17065589.001]
  • [Cites] Leuk Lymphoma. 2007 Jan;48(1):104-8 [17325853.001]
  • [Cites] J Acquir Immune Defic Syndr. 2007 Mar 1;44(3):351-5 [17195763.001]
  • [Cites] Trans Am Ophthalmol Soc. 2006;104:62-70 [17471326.001]
  • [Cites] Br J Ophthalmol. 2007 Aug;91(8):1014-5 [17166894.001]
  • [Cites] Cancer Treat Res. 2007;133:185-213 [17672042.001]
  • [Cites] Leuk Res. 2007 Oct;31(10):1450-2 [17257672.001]
  • [Cites] Ophthalmology. 2007 Jan;114(1):182-6 [17198854.001]
  • [Cites] Nat Med. 1996 Aug;2(8):925-8 [8705864.001]
  • [Cites] Ann Dermatol Venereol. 1996;123(2):90-2 [8761758.001]
  • [Cites] Infect Immun. 1996 Nov;64(11):4872-5 [8890256.001]
  • [Cites] Nippon Ganka Gakkai Zasshi. 1996 Mar;100(3):246-52 [8900592.001]
  • [Cites] CA Cancer J Clin. 1997 Jan-Feb;47(1):5-27 [8996076.001]
  • [Cites] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1997 Feb;83(2):259-64 [9117759.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 1997 Feb;6(2):73-7 [9037556.001]
  • [Cites] Ophthalmology. 1995 Dec;102(12):1994-2006 [9098307.001]
  • [Cites] Am J Ophthalmol. 1997 Apr;123(4):551-2 [9124255.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 1997 Jun;6(6):387-400 [9184771.001]
  • [Cites] Br J Ophthalmol. 1997 Apr;81(4):308-13 [9215061.001]
  • [Cites] Blood. 1997 Jul 15;90(2):776-82 [9226178.001]
  • [Cites] Aust N Z J Ophthalmol. 1997 Aug;25(3):211-5 [9296295.001]
  • [Cites] Clin Microbiol Rev. 1997 Oct;10(4):720-41 [9336670.001]
  • [Cites] J Clin Microbiol. 1999 Oct;37(10):3316-22 [10488198.001]
  • [Cites] Rev Esp Enferm Dig. 1999 Aug;91(8):541-8 [10491486.001]
  • [Cites] Am J Ophthalmol. 1999 Sep;128(3):362-4 [10511035.001]
  • [Cites] Am J Ophthalmol. 1950 Aug;33(8):1203-19 [15432557.001]
  • [Cites] Am J Clin Pathol. 2004 Dec;122(6):938-43 [15539387.001]
  • [Cites] Ann Hematol. 2005 Jan;84(1):13-8 [15309523.001]
  • [Cites] Ophthalmologe. 2004 Oct;101(10):1011-6 [15185119.001]
  • [Cites] Cytokine. 2005 Feb 21;29(4):141-52 [15652446.001]
  • [Cites] Retina. 2005 Jan;25(1):94-8 [15655452.001]
  • [Cites] CA Cancer J Clin. 2005 Jan-Feb;55(1):10-30 [15661684.001]
  • [Cites] Am J Gastroenterol. 2005 Feb;100(2):290-4 [15667484.001]
  • [Cites] Cancer Res. 2005 Feb 1;65(3):939-47 [15705894.001]
  • [Cites] Acta Dermatovenerol Croat. 2005;13(1):22-7 [15788143.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2005 Apr;14(4):773-8 [15824142.001]
  • [Cites] J Virol. 2005 Jul;79(13):8079-89 [15956553.001]
  • [Cites] J Clin Oncol. 2005 Aug 1;23(22):5067-73 [15968003.001]
  • [Cites] Ophthal Plast Reconstr Surg. 2005 Jul;21(4):314-5 [16052151.001]
  • [Cites] Mol Carcinog. 2005 Oct;44(2):77-82 [16075467.001]
  • [Cites] Nat Rev Immunol. 2005 Oct;5(10):749-59 [16175180.001]
  • [Cites] Nippon Ganka Gakkai Zasshi. 2005 Sep;109(9):573-9 [16218435.001]
  • [Cites] Am J Ophthalmol. 2005 Oct;140(4):729-30 [16226528.001]
  • [Cites] Arch Dermatol. 2005 Nov;141(11):1429-34 [16301390.001]
  • (PMID = 18572051.001).
  • [ISSN] 0039-6257
  • [Journal-full-title] Survey of ophthalmology
  • [ISO-abbreviation] Surv Ophthalmol
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / / Z01 EY000222-22
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural; Review
  • [Publication-country] United States
  • [Number-of-references] 248
  • [Other-IDs] NLM/ NIHMS58178; NLM/ PMC2507724
  •  go-up   go-down


89. Moszynski R, Szpurek D, Smolen A, Sajdak S: Comparison of diagnostic usefulness of predictive models in preliminary differentiation of adnexal masses. Int J Gynecol Cancer; 2006 Jan-Feb;16(1):45-51
MedlinePlus Health Information. consumer health - Ovarian Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comparison of diagnostic usefulness of predictive models in preliminary differentiation of adnexal masses.
  • The purpose of this study was to compare prognostic models evaluating the probability of an ovarian cancer occurrence based on a number of clinical and ultrasonographic data in women with adnexal masses.
  • A total of 686 women with adnexal masses underwent the examinations between 1994 and 2002.
  • The results indicate that 431 and 255 patients had a benign and malignant ovarian tumor, respectively.
  • [MeSH-major] Carcinoma / pathology. Carcinoma / ultrasonography. Neural Networks (Computer). Ovarian Neoplasms / pathology. Ovarian Neoplasms / ultrasonography
  • [MeSH-minor] Adult. Age Factors. Aged. Diagnosis, Differential. Early Diagnosis. Female. Humans. Logistic Models. Middle Aged. Neoplasm Staging. Predictive Value of Tests. Prognosis. ROC Curve. Risk Factors. Sensitivity and Specificity. Survival Rate

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Int J Gynecol Cancer. 2007 Mar-Apr;17(2):543; author reply 544 [17309566.001]
  • (PMID = 16445609.001).
  • [ISSN] 1048-891X
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


90. Tran TA, Muller S, Chaudahri PJ, Carlson JA: Cutaneous carcinosarcoma: adnexal vs. epidermal types define high- and low-risk tumors. Results of a meta-analysis. J Cutan Pathol; 2005 Jan;32(1):2-11
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous carcinosarcoma: adnexal vs. epidermal types define high- and low-risk tumors. Results of a meta-analysis.
  • RESULTS: CS occurred in elderly patients (mean of 80 years) on sun-damaged skin, and were keratotic papules of short duration.
  • CS exhibited basal cell carcinoma mixed with atypical fibroxanthoma cell populations.
  • Epidermal-derived (basal or squamous cell carcinoma epithelial component) CS arose on the sun-damaged skin of the head and neck of elderly males (mean age 72 years) and had a 70% 5-year disease-free survival.
  • In contrast, adnexal CS (spiradenocarcinoma, porocarcinoma, proliferating tricholemmal cystic carcinoma, or matrical carcinoma) occurred in younger patients (mean age 58 years), showed recent growth in a long-standing nodule and had a 25% 5-year disease-free survival.
  • Age less than 65 years, recent growth, long-standing skin tumor, and tumor size greater than 2 cm significantly correlated with poor outcome.
  • CONCLUSIONS: Cutaneous CS is an aggressive skin cancer with high risk for advanced disease.
  • [MeSH-major] Carcinosarcoma / pathology. Epithelial Cells / pathology. Neoplasms, Adnexal and Skin Appendage / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Aged. Aged, 80 and over. Biomarkers, Tumor / metabolism. Carcinoma, Basal Cell / classification. Carcinoma, Basal Cell / metabolism. Carcinoma, Basal Cell / pathology. Carcinoma, Squamous Cell / classification. Carcinoma, Squamous Cell / metabolism. Carcinoma, Squamous Cell / pathology. Diagnosis, Differential. Female. Humans. Male. PubMed. Survival Rate

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15660649.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Meta-Analysis
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down


91. Turker O, Dogan I, Kumanlioglu K: Radioiodine accumulation in a large adnexal cystadenofibroma. Thyroid; 2010 May;20(5):561-2
MedlinePlus Health Information. consumer health - Ovarian Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radioiodine accumulation in a large adnexal cystadenofibroma.
  • BACKGROUND: Posttherapy or diagnostic whole-body radioiodine (131I) scans are conducted to observe metastases of differentiated thyroid carcinomas.
  • Here we report a patient with marked radioiodine accumulation in a large adnexal cystadenofibroma, a benign ovarian tumor.
  • Pathologic examination revealed multifocal papillary thyroid carcinoma.
  • CONCLUSIONS: As far as we can ascertain, this is the first report of a radioiodine-accumulating cystadenofibroma.
  • [MeSH-minor] Carcinoma, Papillary / radiotherapy. Carcinoma, Papillary / surgery. False Positive Reactions. Female. Goiter, Nodular / surgery. Humans. Hysterectomy. Iodine Radioisotopes / pharmacokinetics. Middle Aged. Ovariectomy. Thyroid Neoplasms / radiotherapy. Thyroid Neoplasms / surgery. Thyroidectomy

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20406107.001).
  • [ISSN] 1557-9077
  • [Journal-full-title] Thyroid : official journal of the American Thyroid Association
  • [ISO-abbreviation] Thyroid
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Iodine Radioisotopes
  •  go-up   go-down


92. Crippa S, Di Bella C, Faravelli A: Skin adnexal neoplasm closely resembling adenomatoid tumor: a unique occurrence. Int J Surg Pathol; 2006 Apr;14(2):177-8
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Skin adnexal neoplasm closely resembling adenomatoid tumor: a unique occurrence.
  • We describe a primary skin neoplasm located in the left chest wall that closely resembled adenomatoid tumor of male and female genital tract.
  • It occurred in a 52-year-old woman who had undergone a left quadrantectomy with regional lymphadenectomy for invasive ductal carcinoma of the breast 7 years previously.
  • We are unaware of a previous description of this morphologic pattern in a primary skin tumor, which we have interpreted as of skin adnexal and specifically of eccrine sweat gland origin.
  • [MeSH-major] Adnexal Diseases / pathology. Eccrine Glands / pathology. Neoplasms, Second Primary / pathology. Skin Neoplasms / pathology. Thoracic Wall / pathology
  • [MeSH-minor] Adenomatoid Tumor / pathology. Aged. Breast Neoplasms / surgery. Carcinoma, Ductal / surgery. Diagnosis, Differential. Female. Humans. Immunohistochemistry

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16703184.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


93. Vidal VP, Ortonne N, Schedl A: SOX9 expression is a general marker of basal cell carcinoma and adnexal-related neoplasms. J Cutan Pathol; 2008 Apr;35(4):373-9
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] SOX9 expression is a general marker of basal cell carcinoma and adnexal-related neoplasms.
  • Activation of the Shh pathway is a major cause of cutaneous basal cell carcinoma (BCC).
  • Here we test whether activation of SOX9 is a general feature of BCC, or whether it could be used as a biomarker to better define subtypes of these skin tumors.
  • In addition we investigated SOX9 expression in other skin epidermal tumors.
  • SOX9 expression was detected in all adnexal tumors analyzed and absent in Bowen's disease and Merkel tumor.
  • CONCLUSIONS: SOX9 expression is a general feature of BCC and adnexal skin neoplasms, suggesting a contribution of SOX9 to the pathogenesis of these tumors.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Carcinoma, Basal Cell / metabolism. High Mobility Group Proteins / metabolism. Neoplasms, Adnexal and Skin Appendage / metabolism. Skin Neoplasms / metabolism. Transcription Factors / metabolism
  • [MeSH-minor] Diagnosis, Differential. Fluorescent Antibody Technique, Indirect. Humans. Microscopy, Fluorescence. SOX9 Transcription Factor

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18333897.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / High Mobility Group Proteins; 0 / SOX9 Transcription Factor; 0 / SOX9 protein, human; 0 / Transcription Factors
  •  go-up   go-down


94. Kazakov DV, Sima R, Vanecek T, Kutzner H, Palmedo G, Kacerovska D, Grossmann P, Michal M: Mutations in exon 3 of the CTNNB1 gene (beta-catenin gene) in cutaneous adnexal tumors. Am J Dermatopathol; 2009 May;31(3):248-55
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mutations in exon 3 of the CTNNB1 gene (beta-catenin gene) in cutaneous adnexal tumors.
  • Previous studies suggested that mutant beta-catenin gene cells in cutaneous adnexal tumors with matrical differentiation contribute to their tumorigenesis.
  • Except for pilomatricoma and pilomatrical carcinoma, only a handful of other cutaneous adnexal tumor types have been studied.
  • DNA was extracted from 86 lesions including 17 proliferating tricholemmal and trichilemmal tumors, 15 trichoblastomas, 7 trichoadenomas, 4 pilomatricomas, 1 pilomatrical carcinoma, 4 basal cell carcinomas (BCCs) with shadow cells, 2 trichofolliculomas, 3 BCCs with sebaceous differentiation, 9 sebaceous adenomas, 6 sebaceomas, 14 sebaceous carcinomas (both ocular and extraocular forms), 2 gigantic horns, and 2 apocrine mixed tumors with shadow cells and subjected to polymerase chain reaction with newly designed primers encompassing glycogen synthase kinase-3beta phosphorylation sites of the CTNNB1 gene.
  • These included 5 different point mutations, 3 of them identified in 2 different tumors: S23N (cribriform trichoblastoma), D32Y (pilomatricoma and craniopharyngioma), G34R (pilomatrical carcinoma and craniopharyngioma), S37F (2 BCCs with shadow cell differentiation), and G34V (craniopharyngioma).
  • This study broadens the list of cutaneous adnexal tumors harboring CTNNB1 mutations and extends the listing of the mutations occurring in these neoplasms.
  • [MeSH-major] Exons. Mutation. Neoplasms, Adnexal and Skin Appendage / genetics. Skin Neoplasms / genetics. beta Catenin / genetics

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19384065.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CTNNB1 protein, human; 0 / beta Catenin
  •  go-up   go-down


95. Krahl D, Sellheyer K: p75 Neurotrophin receptor differentiates between morphoeic basal cell carcinoma and desmoplastic trichoepithelioma: insights into the histogenesis of adnexal tumours based on embryology and hair follicle biology. Br J Dermatol; 2010 Jul;163(1):138-45
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] p75 Neurotrophin receptor differentiates between morphoeic basal cell carcinoma and desmoplastic trichoepithelioma: insights into the histogenesis of adnexal tumours based on embryology and hair follicle biology.
  • However, a link between the embryology of the skin and the histogenesis of adnexal tumours has been largely overlooked.
  • We therefore speculated that it is involved in the histogenesis of follicular adnexal tumours.
  • One of the most challenging diagnoses in dermatopathology is differentiating morphoeic basal cell carcinoma from desmoplastic trichoepithelioma.
  • OBJECTIVES: To describe the expression pattern of p75NTR during cutaneous embryogenesis, in the adult hair follicle and in morphoeic basal cell carcinoma and desmoplastic trichoepithelioma.
  • RESULTS: All 17 desmoplastic trichoepitheliomas were immunoreactive with > 80% of the cells stained, whereas 12 of the 14 (86%) morphoeic basal cell carcinomas were p75NTR negative.
  • In the two positive cases of morphoeic basal cell carcinoma < 30% of cells were labelled.
  • In contrast, the lack of p75NTR expression in morphoeic basal cell carcinoma favours a concept of this tumour as a more primitive follicular lesion with the characteristics of a carcinoma and not a hamartoma.
  • We suggest including p75NTR as a tool in the differential diagnosis between morphoeic basal cell carcinoma and desmoplastic trichoepithelioma.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Carcinoma, Basal Cell / metabolism. Hair Follicle / metabolism. Neoplasms, Adnexal and Skin Appendage / metabolism. Receptor, Nerve Growth Factor / metabolism. Skin Neoplasms / metabolism
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Diagnosis, Differential. Female. Humans. Male. Merkel Cells / metabolism. Middle Aged. Skin / embryology. Skin / metabolism

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20184585.001).
  • [ISSN] 1365-2133
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Receptor, Nerve Growth Factor
  •  go-up   go-down


96. Marcos Sánchez F, Sánchez Díaz E, Marrupe González D, Albo Castaño MI, Viana Alonso A, Juárez Ucelay F: [Carcinoma of the Fallopian tube: a case]. An Med Interna; 2006 Feb;23(2):83-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Carcinoma of the Fallopian tube: a case].
  • [Transliterated title] Un caso de carcinoma de trompa de Falopio.
  • The case of a 43-years old woman with previous history of mental retardation and major depressive syndrome, consulting for metrorrhagia is presented.
  • At physical examination a right adnexal mass was detected on palpation.
  • [MeSH-major] Fallopian Tube Neoplasms / diagnosis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16566658.001).
  • [ISSN] 0212-7199
  • [Journal-full-title] Anales de medicina interna (Madrid, Spain : 1984)
  • [ISO-abbreviation] An Med Interna
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  •  go-up   go-down


97. Tongsong T, Wanapirak C, Sukpan K, Khunamornpong S, Pathumbal A: Subjective sonographic assessment for differentiation between malignant and benign adnexal masses. Asian Pac J Cancer Prev; 2007 Jan-Mar;8(1):124-6
MedlinePlus Health Information. consumer health - Ovarian Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Subjective sonographic assessment for differentiation between malignant and benign adnexal masses.
  • OBJECTIVE: To determine the accuracy of subjective sonographic assessment in distinguishing between benign and malignant adnexal masses.
  • METHODS: The patients scheduled for elective surgery due to adnexal masses were recruited into the study.
  • All patients were sonographically examined within 72 hours of surgery were subjectively evaluated by the experienced sonographer, who had no any information of the patients, to differentiate between benign and malignant adnexal masses based on sonographic morphology.
  • RESULTS: One hundred and fifty-eight patients with 174 adnexal masses, (benign; 108 and malignant;.
  • CONCLUSIONS: Subjective evaluation of sonographic morphology has high accuracy in differentiating between benign and malignant adnexal masses.
  • [MeSH-minor] Adenocarcinoma, Mucinous / ultrastructure. Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Endometrioid / ultrastructure. Cross-Sectional Studies. Cystadenoma, Serous / ultrastructure. Diagnosis, Differential. Female. Humans. Incidence. Middle Aged. Neoplasm Staging. Predictive Value of Tests. ROC Curve. Risk Factors. Sensitivity and Specificity

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17477786.001).
  • [ISSN] 1513-7368
  • [Journal-full-title] Asian Pacific journal of cancer prevention : APJCP
  • [ISO-abbreviation] Asian Pac. J. Cancer Prev.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Thailand
  •  go-up   go-down


98. Arteaga-Gómez AC, Aranda-Flores C, Márquez-Acosta G, Colín-Valenzuela A: [Adnexal tumor and pregnancy: diagnosis and treatment]. Ginecol Obstet Mex; 2010 Mar;78(3):160-7
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Adnexal tumor and pregnancy: diagnosis and treatment].
  • [Transliterated title] Tumor anexial y embarazo: diagnóstico y tratamiento.
  • BACKGROUND: The finding of adnexal masses during pregnancy is an exceptional event.
  • OBJECTIVE: Describe a case series of patients with adnexal mass and pregnancy.
  • MATERIAL AND METHODS: We retrospectively reviewed the medical records of patients who had diagnosis of pregnancy and adnexal over a period of five years.
  • The diagnosis was established by ultrasound (USG) in 95% of cases, 48% had cystic characteristics, the mean diameter of the tumor was 99 +/- 42 mm.
  • The most frequent histological diagnosis were serous cyst (40%), mature teratoma (28%), mucinous (6%), malignancy (4%).
  • CONCLUSIONS: The USG constitute a safe method for the diagnosis, but the image method with the highest positive predictive value is the MRI.
  • If surgery is decided, it should be performed between 16 a 23 weeks of pregnancy, and it's recommended to send the tumor to histological diagnosis, in case of malignancy the surgery will continue according to the tumor stage.
  • [MeSH-major] Adnexa Uteri / pathology. Genital Neoplasms, Female / surgery. Genital Neoplasms, Female / ultrasonography. Pregnancy Complications, Neoplastic / surgery. Pregnancy Complications, Neoplastic / ultrasonography
  • [MeSH-minor] Adnexal Diseases / blood. Adnexal Diseases / surgery. Adnexal Diseases / ultrasonography. Adolescent. Adult. Biomarkers, Tumor / blood. Carcinoma / blood. Carcinoma / surgery. Carcinoma / ultrasonography. Cesarean Section. Cystadenoma / blood. Cystadenoma / surgery. Cystadenoma / ultrasonography. Cysts / blood. Cysts / surgery. Cysts / ultrasonography. Female. Gestational Age. Humans. Incidence. Incidental Findings. Infant, Newborn. Middle Aged. Pregnancy. Retrospective Studies. Teratoma / blood. Teratoma / surgery. Teratoma / ultrasonography. Ultrasonography, Prenatal. Young Adult

  • Genetic Alliance. consumer health - Pregnancy.
  • MedlinePlus Health Information. consumer health - Tumors and Pregnancy.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20939220.001).
  • [ISSN] 0300-9041
  • [Journal-full-title] Ginecología y obstetricia de México
  • [ISO-abbreviation] Ginecol Obstet Mex
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Mexico
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down


99. Rütten A, Kutzner H, Mentzel T, Hantschke M, Eckert F, Angulo J, Rodríguez Peralto JL, Requena L: Primary cutaneous cribriform apocrine carcinoma: a clinicopathologic and immunohistochemical study of 26 cases of an under-recognized cutaneous adnexal neoplasm. J Am Acad Dermatol; 2009 Oct;61(4):644-51

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary cutaneous cribriform apocrine carcinoma: a clinicopathologic and immunohistochemical study of 26 cases of an under-recognized cutaneous adnexal neoplasm.
  • BACKGROUND: Cribriform carcinoma is the histopathologic variant of cutaneous apocrine carcinoma characterized by interconnected solid aggregations of neoplastic cells that are punctuated by small round spaces.
  • OBJECTIVE: To describe the histopathologic and immunohistochemical characteristics of this under-recognized cutaneous adnexal neoplasm.
  • METHODS: Twenty-six cases of primary cutaneous cribriform apocrine carcinoma were clinically, histopathologically, and immunohistochemically studied.
  • CONCLUSIONS: Primary cutaneous cribriform apocrine carcinoma is a distinctive but little-known variant of cutaneous apocrine carcinoma.
  • [MeSH-major] Adenocarcinoma / metabolism. Adenocarcinoma / pathology. Biomarkers, Tumor / metabolism. Neoplasms, Adnexal and Skin Appendage / metabolism. Neoplasms, Adnexal and Skin Appendage / pathology
  • [MeSH-minor] Adult. Aged. Apocrine Glands / pathology. Biopsy. Carcinoma, Adenoid Cystic / metabolism. Carcinoma, Adenoid Cystic / pathology. Cytoplasm / pathology. Cytoplasm / ultrastructure. Diagnosis, Differential. Epithelial Cells / pathology. Epithelial Cells / ultrastructure. Female. Humans. Immunohistochemistry. Male. Microscopy, Electron. Microvilli / pathology. Microvilli / ultrastructure. Middle Aged. Young Adult

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] J Am Acad Dermatol. 2011 Mar;64(3):599-601 [21315957.001]
  • (PMID = 19751882.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down


100. Liang H, Wu H, Giorgadze TA, Sariya D, Bellucci KS, Veerappan R, Liegl B, Acs G, Elenitsas R, Shukla S, Youngberg GA, Coogan PS, Pasha T, Zhang PJ, Xu X: Podoplanin is a highly sensitive and specific marker to distinguish primary skin adnexal carcinomas from adenocarcinomas metastatic to skin. Am J Surg Pathol; 2007 Feb;31(2):304-10
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Podoplanin is a highly sensitive and specific marker to distinguish primary skin adnexal carcinomas from adenocarcinomas metastatic to skin.
  • Distinction of primary skin adnexal carcinomas from cutaneous metastasis of adenocarcinomas is challenging.
  • In this study, we evaluated podoplanin immunoreactivity in a series of primary skin adnexal tumors and adenocarcinomas metastatic to skin using a D2-40 antibody.
  • The initial test series were composed of a total of 93 cases including 32 primary skin adnexal carcinomas, 46 benign primary adnexal tumors, and 15 cutaneous metastatic adenocarcinomas.
  • We found that variable D2-40 reactivity was seen in all of the primary cutaneous carcinomas including sebaceous carcinomas (10/10), squamous cell carcinomas (10/10), porocarcinomas (4/4), trichilemmal carcinomas (4/4), skin adnexal carcinomas not otherwise specified (4/4), and in the majority of benign skin adnexal tumors.
  • To confirm the initial findings and to further explore the utility of podoplanin reactivity in the distinction of these tumors, we also examined a test set of 35 unknown cases, including 21 adenocarcinomas metastatic to skin and 14 primary adnexal tumors, in a blinded fashion.
  • Of the 13 D2-40 positive cases, 12 were proven to be primary adnexal tumors.
  • Our results suggest that podoplanin can be a useful tool to distinguish primary skin adnexal carcinomas form adenocarcinomas metastatic to skin with high sensitivity (94.5%) and specificity (97.2%).
  • [MeSH-major] Adenocarcinoma / secondary. Biomarkers, Tumor / metabolism. Carcinoma, Squamous Cell / pathology. Membrane Glycoproteins / metabolism. Neoplasms, Adnexal and Skin Appendage / pathology. Skin Neoplasms / secondary
  • [MeSH-minor] Diagnosis, Differential. Humans. Predictive Value of Tests. Sebaceous Gland Neoplasms / metabolism. Sebaceous Gland Neoplasms / pathology. Single-Blind Method

  • MedlinePlus Health Information. consumer health - Skin Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17255777.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Membrane Glycoproteins; 0 / PDPN protein, human
  •  go-up   go-down






Advertisement