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1. Bastian PJ, Hutterer GC, Shariat SF, Rogers CG, Palapattu GS, Lotan Y, Vazina A, Amiel GE, Gupta A, Sagalowsky AI, Lerner SP, Schoenberg MP, Karakiewicz PI, Bladder Cancer Research Consortium: Macroscopic, but not microscopic, perivesical fat invasion at radical cystectomy is an adverse predictor of recurrence and survival. BJU Int; 2008 Feb;101(4):450-4
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  • [Title] Macroscopic, but not microscopic, perivesical fat invasion at radical cystectomy is an adverse predictor of recurrence and survival.
  • OBJECTIVE: To examine whether the presence of microscopic (pT3a) or macroscopic (pT3b) disease worsens the prognosis relative to pT2 disease at radical cystectomy, as the prognostic significance of pT3a vs pT3b perivesical fat invasion (pT3) is controversial.
  • PATIENTS AND METHODS: In all, 242 patients with pT3 disease (pT3a in 88, pT3b in 121) had radical cystectomy and bilateral pelvic lymphadenectomy for transitional cell carcinoma of the urinary bladder; they were compared with 172 who had organ-confined muscle-invasive disease (pT2).
  • For the analyses we used univariable and multivariable Cox regression models of recurrence and cancer-specific survival, adjusted for age, tumour grade, lymphovascular invasion and the presence of lymph node metastases.
  • RESULTS: In multivariable analyses, microscopic perivesical fat extension (pT3a) was not associated with higher recurrence (P = 0.3) or the mortality rate (P = 0.06) vs pT2 disease.
  • Conversely, the presence of deep perivesical fat extension (pT3b) was associated with 1.8 times the rate of recurrence (P = 0.002) and with twice the rate of death (P = 0.001) vs pT2 disease.
  • CONCLUSION: These findings imply that a detailed assessment of the cystectomy specimen for the presence of microscopic perivesical fat invasion might not be necessary, as the presence of pT3a disease has no strong effect on recurrence or mortality.
  • Moreover, patients with pT3a disease might not require more aggressive therapy than their counterparts with pT2 disease.
  • [MeSH-major] Adipose Tissue / pathology. Carcinoma, Transitional Cell / pathology. Cystectomy. Neoplasm Recurrence, Local / pathology. Urinary Bladder Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Cohort Studies. Female. Follow-Up Studies. Humans. Male. Middle Aged. Multivariate Analysis. Neoplasm Invasiveness / pathology. Neoplasm Staging / methods. Prognosis. Survival Analysis. Treatment Outcome

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  • (PMID = 17850359.001).
  • [ISSN] 1464-410X
  • [Journal-full-title] BJU international
  • [ISO-abbreviation] BJU Int.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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2. Tazoe J, Okuyama C, Iehara T, Hosoi H, Nishimura T: Unusual fatty metamorphosis observed in diffuse liver metastases of stage 4S neuroblastoma. Pediatr Radiol; 2010 May;40(5):777-80
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  • [Title] Unusual fatty metamorphosis observed in diffuse liver metastases of stage 4S neuroblastoma.
  • We report a case of stage 4S neuroblastoma in which CT showed diffuse liver metastases containing a geographical fatty area in the periportal region.
  • MRI showed this abnormality to correspond to an area with an unusual pattern of fatty change. (123)I-metaiodobenzylguanidine (MIBG) scintigraphy demonstrated increased accumulation throughout the liver, except for the region showing fatty change.
  • To the best of our knowledge, this is the first report of liver metastases from neuroblastoma with geographical fatty infiltration.
  • [MeSH-major] Adipose Tissue / diagnostic imaging. Adipose Tissue / pathology. Liver Neoplasms / diagnosis. Liver Neoplasms / secondary. Neuroblastoma / diagnosis. Neuroblastoma / secondary
  • [MeSH-minor] Female. Humans. Infant. Magnetic Resonance Imaging. Neoplasm Staging. Radionuclide Imaging

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  • [Cites] J Clin Oncol. 1993 Aug;11(8):1466-77 [8336186.001]
  • [Cites] Oncologist. 2003;8(3):278-92 [12773750.001]
  • [Cites] Pediatr Radiol. 1986;16(2):107-9 [3513106.001]
  • [Cites] Pediatr Blood Cancer. 2006 Mar;46(3):278-84 [16124002.001]
  • [Cites] J Nucl Med. 1998 Apr;39(4):679-88 [9544682.001]
  • (PMID = 20180113.001).
  • [ISSN] 1432-1998
  • [Journal-full-title] Pediatric radiology
  • [ISO-abbreviation] Pediatr Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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3. Ruiz E, Pozo P, Toselli L, Fernández M, Christiansen S, Lambertini R: Unusual benign paratesticular tumor in an infant mimicking rhabdomyosarcoma. Urology; 2008 Jun;71(6):1067-9
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  • [Title] Unusual benign paratesticular tumor in an infant mimicking rhabdomyosarcoma.
  • Paratesticular tumors are extremely rare, with paratesticular rhabdomyosarcoma being the most common finding.
  • A 6-month-old boy presented with an asymptomatic, right intrascrotal mass whereby the testicle was surrounded by a friable lipomatous tumor.
  • [MeSH-major] Rhabdomyosarcoma / pathology. Testicular Diseases / pathology. Testicular Neoplasms / pathology. Xanthogranuloma, Juvenile / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans. Infant. Male

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  • (PMID = 18538690.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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4. Rajeswaran R, Murthy J, Chandrasekharan A, Joseph S: Case Report: Congenital infiltrating lipomatosis of face. Indian J Radiol Imaging; 2008 Nov;18(4):306-9
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  • Congenital infiltrating lipomatosis of the face is a rare condition characterized by diffuse fatty infiltration of the facial soft tissues.
  • It is a type of lipomatous tumor that is congenital in origin; it is rare and seen usually in childhood.

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  • [Cites] Pediatr Radiol. 2006 Nov;36(11):1159-62 [16953375.001]
  • [Cites] Plast Reconstr Surg. 1983 Aug;72(2):158-64 [6192455.001]
  • [Cites] AJNR Am J Neuroradiol. 2003 Feb;24(2):283-6 [12591650.001]
  • [Cites] Chang Gung Med J. 2002 Mar;25(3):194-200 [12022741.001]
  • [Cites] Plast Reconstr Surg. 2001 Nov;108(6):1544-54 [11711926.001]
  • (PMID = 19774187.001).
  • [ISSN] 0971-3026
  • [Journal-full-title] The Indian journal of radiology & imaging
  • [ISO-abbreviation] Indian J Radiol Imaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2747453
  • [Keywords] NOTNLM ; Congenital / lipomatosis
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5. Bertini R, Roscigno M, Freschi M, Strada E, Petralia G, Pasta A, Matloob R, Sozzi F, Da Pozzo L, Colombo R, Guazzoni G, Doglioni C, Montorsi F, Rigatti P: Renal sinus fat invasion in pT3a clear cell renal cell carcinoma affects outcomes of patients without nodal involvement or distant metastases. J Urol; 2009 May;181(5):2027-32
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  • In the overall population sinus fat invasion did not reach independent predictive status in terms of cancer specific survival on multivariate Cox regression analysis after adjusting for age, performance status, tumor dimension, tumor grade, synchronous metastases, nodal involvement, sarcomatoid differentiation and coagulative necrosis.
  • However, sinus fat invasion is not associated with worse cancer specific survival in cases of metastatic disease.
  • [MeSH-major] Adipose Tissue / pathology. Carcinoma, Renal Cell / mortality. Carcinoma, Renal Cell / pathology. Kidney Neoplasms / mortality. Kidney Neoplasms / pathology. Neoplasm Invasiveness / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Analysis of Variance. Cohort Studies. Disease-Free Survival. Female. Humans. Kidney Pelvis / pathology. Lymph Nodes / pathology. Male. Middle Aged. Multivariate Analysis. Neoplasm Staging. Probability. Prognosis. Proportional Hazards Models. Retrospective Studies. Survival Analysis


6. Karapanagiotou EM, Tsochatzis EA, Dilana KD, Tourkantonis I, Gratsias I, Syrigos KN: The significance of leptin, adiponectin, and resistin serum levels in non-small cell lung cancer (NSCLC). Lung Cancer; 2008 Sep;61(3):391-7
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  • SUMMARY: Adipose tissue secretes adipokines with proinflammatory and anti-inflammatory properties.
  • Our aim was to assess the role of adipose tissue in generalized inflammatory state of advanced NSCLC patients and the possible use of leptin, adiponectin and resistin as diagnostic and prognostic markers.
  • Correlation of adipose tissue with weight loss in advanced NSCLC patients was also studied.
  • Adipokine serum levels were determined at diagnosis, at the end of first-line chemotherapy and at the time of disease progression for those who responded to treatment.
  • Multivariate analysis showed that these adipokines at diagnosis could not be used as predictive factors for overall survival or time to progression.
  • [MeSH-major] Adiponectin / blood. Carcinoma, Non-Small-Cell Lung / blood. Leptin / blood. Lung Neoplasms / blood. Resistin / blood
  • [MeSH-minor] Analysis of Variance. Biomarkers, Tumor / blood. Enzyme-Linked Immunosorbent Assay. Female. Humans. Male. Middle Aged. Neoplasm Staging. Proportional Hazards Models. Prospective Studies. Statistics, Nonparametric


7. Novikov VV, Novikov GV, Fesenko EE: Effect of weak combined static and extremely low-frequency alternating magnetic fields on tumor growth in mice inoculated with the Ehrlich ascites carcinoma. Bioelectromagnetics; 2009 Jul;30(5):343-51
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  • [Title] Effect of weak combined static and extremely low-frequency alternating magnetic fields on tumor growth in mice inoculated with the Ehrlich ascites carcinoma.
  • It was shown that the exposure of mice with EAC to combined MFs causes structural changes in some organs (liver, adrenal glands), which are probably due to the total degradation of the tumor tissue.
  • In mice with transplanted EAC, the tumor tissue after exposure to weak MFs was practically absent, as distinct from control animals in which the invasion of the tumor into the adipose tissue surrounding the kidneys, mesenteric lymph nodes, and spermatic appendages was observed.
  • In animals without tumors, no pathological deviations from the norm in the structure of organs and tissues occurred after exposure to weak MF, indicating that this factor per se is not toxic to the organism.
  • [MeSH-major] Carcinoma, Ehrlich Tumor / pathology. Carcinoma, Ehrlich Tumor / therapy. Magnetic Field Therapy / methods. Magnetics

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  • [Copyright] (c) 2009 Wiley-Liss, Inc.
  • (PMID = 19267367.001).
  • [ISSN] 1521-186X
  • [Journal-full-title] Bioelectromagnetics
  • [ISO-abbreviation] Bioelectromagnetics
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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8. Pons Y, Ukkola-Pons E, Clément P, Gauthier J, Conessa C: Relevance of 5 different imaging signs in the evaluation of carotid artery invasion by cervical lymphadenopathy in head and neck squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 May;109(5):775-8
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  • SUBJECTS AND METHODS: Between September 2001 and September 2008, 22 patients (20 men and 2 women) presented with lymph node metastasis of a head and neck squamous cell carcinoma that invaded the carotid artery.
  • In comparison, the isolated existence of encasement of more than 180 degrees or segmental obliteration of fat could not strictly indicate massive invasion of the carotid artery; thus, CAD could be planned.
  • [MeSH-major] Carcinoma, Squamous Cell / secondary. Carotid Arteries / pathology. Carotid Artery Diseases / diagnosis. Head and Neck Neoplasms / pathology. Lymphatic Metastasis / diagnosis
  • [MeSH-minor] Adipose Tissue / pathology. Adipose Tissue / radiography. Contrast Media. Dissection / methods. Elastic Tissue / pathology. Elastic Tissue / radiography. Female. Humans. Lymph Nodes / pathology. Lymph Nodes / radiography. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Invasiveness. Retrospective Studies. Tomography, X-Ray Computed


9. Petrolla AA, Xin W: Hepatic angiomyolipoma. Arch Pathol Lab Med; 2008 Oct;132(10):1679-82
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  • Hepatic angiomyolipoma is a rare, benign, hepatic mesenchymal neoplasm found in both males and females, and most commonly in adult females.
  • Hepatic angiomyolipomas are composed of varying amounts of smooth muscle cells, adipose tissue, and vessels.
  • The smooth muscle cell component is the most specific to the diagnosis.
  • The differential diagnosis includes hepatocellular carcinoma, hepatic adenoma, leiomyoma, hepatoblastoma, melanoma, and gastrointestinal stromal tumor.
  • If the diagnosis of hepatic angiomyolipoma has been made, it can be followed conservatively or surgically resected.
  • [MeSH-major] Angiomyolipoma / pathology. Liver Neoplasms / pathology
  • [MeSH-minor] Antigens, Neoplasm / metabolism. Female. Humans. MART-1 Antigen. Male. Melanoma-Specific Antigens. Neoplasm Proteins / metabolism. S100 Proteins / metabolism

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  • (PMID = 18834230.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / MART-1 Antigen; 0 / MLANA protein, human; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 0 / S100 Proteins
  • [Number-of-references] 17
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10. Hertzel AV, Smith LA, Berg AH, Cline GW, Shulman GI, Scherer PE, Bernlohr DA: Lipid metabolism and adipokine levels in fatty acid-binding protein null and transgenic mice. Am J Physiol Endocrinol Metab; 2006 May;290(5):E814-23
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  • [Title] Lipid metabolism and adipokine levels in fatty acid-binding protein null and transgenic mice.
  • Fatty acid-binding proteins (FABPs) facilitate the diffusion of fatty acids within cellular cytoplasm.
  • Compared with C57Bl/6J mice maintained on a high-fat diet, adipose-FABP (A-FABP) null mice exhibit increased fat mass, decreased lipolysis, increased muscle glucose oxidation, and attenuated insulin resistance, whereas overexpression of epithelial-FABP (E-FABP) in adipose tissue results in decreased fat mass, increased lipolysis, and potentiated insulin resistance.
  • In contrast, de novo lipogenesis and expression of genes encoding lipoprotein lipase, CD36, long-chain acyl-CoA synthetase 5, and diacylglycerol acyltransferase are increased in A-FABP/aP2 null mice relative to E-FABP transgenic animals.
  • Consistent with an increase in de novo lipogenesis, there was an increase in adipose C16:0 and C16:1 acyl-CoA pools.
  • There were no changes in serum free fatty acids between genotypes.
  • Serum levels of resistin were decreased in the E-FABP transgenic mice, whereas serum and tissue adiponectin were increased in A-FABP/aP2 null mice and decreased in E-FABP transgenic animals; leptin expression was unaffected.

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  • (PMID = 16303844.001).
  • [ISSN] 0193-1849
  • [Journal-full-title] American journal of physiology. Endocrinology and metabolism
  • [ISO-abbreviation] Am. J. Physiol. Endocrinol. Metab.
  • [Language] ENG
  • [Grant] United States / NIDDK NIH HHS / DK / R01 DK040936; United States / NIDDK NIH HHS / DK / DK-053189; United States / NIDDK NIH HHS / DK / DK-40936; United States / NIDDK NIH HHS / DK / DK-59635
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Adiponectin; 0 / Carrier Proteins; 0 / Fabp4 protein, mouse; 0 / Fabp5 protein, mouse; 0 / Fatty Acid-Binding Proteins; 0 / Fatty Acids; 0 / Fatty Acids, Nonesterified; 0 / Fatty Acids, Unsaturated; 0 / Leptin; 0 / Neoplasm Proteins; 0 / Peptide Hormones; 0 / Phosphoproteins; 0 / Resistin; 0 / perilipin 1
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11. Dietrich D, Schuster M, Lesche R, Haedicke W, Kristiansen G: [Multiplexed methylation analysis--a new technology to analyse the methylation pattern of laser microdissected cells of normal breast tissue, DCIS and invasive ductal carcinoma of the breast]. Verh Dtsch Ges Pathol; 2007;91:197-207
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  • [Title] [Multiplexed methylation analysis--a new technology to analyse the methylation pattern of laser microdissected cells of normal breast tissue, DCIS and invasive ductal carcinoma of the breast].
  • AIMS: DNA methylation has been shown to play an important role in breast cancer pathogenesis, but up until now it is not clear how the tissue components contribute to the overall methylation of the sample, because microdissection does not provide sufficient material for most standard methylation assays.
  • METHODS: We developed a technology to analyse several methylation markers in a limited number of cells dissected from tissue sections.
  • The microdissected samples were from the invasive part, the intraductal part, the stroma, tumor infiltrating lymphocytes, chest wall muscle, adipose tissue and healthy ducts.
  • In all analysed patients PITX2 and RASSF1A were highly methylated in invasive and intraductal carcinoma cells compared to other tissue components.
  • PITX2 showed some methylation in normal adjacent breast tissue.
  • The methylation of the individual markers varied little within one tissue type and between blocks.
  • CONCLUSIONS: This technology is a powerful tool to analyse the methylation of multiple markers in different microdissected tissue components.
  • Methylation patterns may differ significantly between different markers and tissue components.
  • [MeSH-major] Breast / cytology. Breast Neoplasms / genetics. Breast Neoplasms / pathology. DNA Methylation. DNA, Neoplasm / genetics

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  • (PMID = 18314615.001).
  • [ISSN] 0070-4113
  • [Journal-full-title] Verhandlungen der Deutschen Gesellschaft für Pathologie
  • [ISO-abbreviation] Verh Dtsch Ges Pathol
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / DNA, Neoplasm
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12. Naya Y, Zenbutsu S, Araki K, Nakamura K, Kobayashi M, Kamijima S, Imamoto T, Nihei N, Suzuki H, Ichikawa T, Igarashi T: Influence of visceral obesity on oncologic outcome in patients with renal cell carcinoma. Urol Int; 2010;85(1):30-6
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  • OBJECTIVE: At present, computed tomography (CT) is used in almost all patients with renal tumors.
  • We aimed to investigate the relationship between visceral adipose tissue (VAT), as assessed by CT, and various other factors in patients with renal cell carcinoma (RCC).
  • Pathological stage, microvascular invasion, tumor grade, performance status, C-reactive protein, BMI, hypertension, hyperlipemia, hyperglycemia, history of smoking and cause-specific survival rate were examined in relation to VAT, and multivariate Cox regression analysis was used to determine significant predictors of cause-specific survival.
  • RESULTS: VAT in patients with stage I disease was significantly greater than that in patients with more advanced disease (p = 0.0219).
  • [MeSH-major] Adiposity. Carcinoma, Renal Cell / surgery. Intra-Abdominal Fat / physiopathology. Kidney Neoplasms / surgery. Nephrectomy. Obesity / complications
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Humans. Japan. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging. Proportional Hazards Models. Retrospective Studies. Risk Assessment. Risk Factors. Survival Rate. Time Factors. Tomography, X-Ray Computed. Treatment Outcome


13. Abe H, Schmidt RA, Kulkarni K, Sennett CA, Mueller JS, Newstead GM: Axillary lymph nodes suspicious for breast cancer metastasis: sampling with US-guided 14-gauge core-needle biopsy--clinical experience in 100 patients. Radiology; 2009 Jan;250(1):41-9
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  • The absence of any discernible fatty hilum was also noted.
  • All 44 patients who did not undergo CNB because of negative US results subsequently underwent SLNB, which revealed lymph node metastasis in 12 (27%) patients.
  • Cortical thickening was found in 63 (79%) of the total of 80 metastatic nodes, but only a minority (n = 26 [32%]) of the nodes had an absent fatty hilum.
  • Both absence of a fatty hilum (metastasis detected in 26 [93%] of 28 nodes) and cortical thickening combined with NHBF (metastasis detected in 52 [81%] of 64 nodes) had a high positive predictive value.
  • [MeSH-major] Biopsy, Needle. Breast Neoplasms / ultrasonography. Lymph Nodes / ultrasonography. Lymphatic Metastasis / ultrasonography. Ultrasonography, Interventional. Ultrasonography, Mammary
  • [MeSH-minor] Adipose Tissue / pathology. Adipose Tissue / ultrasonography. Adult. Aged. Aged, 80 and over. Axilla. Carcinoma, Ductal / pathology. Carcinoma, Ductal / ultrasonography. Carcinoma, Intraductal, Noninfiltrating / pathology. Carcinoma, Intraductal, Noninfiltrating / ultrasonography. Carcinoma, Lobular / pathology. Carcinoma, Lobular / ultrasonography. Female. Humans. Lymph Node Excision. Middle Aged. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / ultrasonography. Neoplasm Staging. Prognosis. Retrospective Studies. Sensitivity and Specificity. Sentinel Lymph Node Biopsy. Ultrasonography, Doppler, Color

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  • [Copyright] (c) RSNA, 2008.
  • (PMID = 18955508.001).
  • [ISSN] 1527-1315
  • [Journal-full-title] Radiology
  • [ISO-abbreviation] Radiology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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14. Chen CW, Chang WC, Lee HS, Ko KH, Chang CC, Huang GS: MRI features of lipoblastoma: differentiating from other palpable lipomatous tumor in pediatric patients. Clin Imaging; 2010 Nov-Dec;34(6):453-7
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  • [Title] MRI features of lipoblastoma: differentiating from other palpable lipomatous tumor in pediatric patients.
  • The purpose of this study was to describe the magnetic resonance imaging (MRI) features of lipoblastomas in pediatric patients and to differentiate them from other palpable benign lipomatous tumors.
  • The relatively specific MRI features of nonenhancing cystic change and enhancing soft tissue nodules seen in lipoblastoma may help to differentiate it from other types of lipomatous tumor in pediatric patients.
  • [MeSH-major] Lipoma / diagnosis. Magnetic Resonance Imaging / methods. Palpation. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Diagnosis, Differential. Female. Humans. Infant. Male

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  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 21092875.001).
  • [ISSN] 1873-4499
  • [Journal-full-title] Clinical imaging
  • [ISO-abbreviation] Clin Imaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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15. Mete O, Rotstein L, Asa SL: Controversies in thyroid pathology: thyroid capsule invasion and extrathyroidal extension. Ann Surg Oncol; 2010 Feb;17(2):386-91
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  • In this article, we confront another controversy, the definition of a thyroid "capsule" to clarify what constitutes extrathyroidal extension (ETE) and its clinical significance in the management of patients with differentiated thyroid carcinomas.
  • Moreover, the presence of adipose tissue within the thyroid gland and its pseudocapsule implies that thyroid tumor within fat tissue cannot be accepted as a criterion of ETE by that thyroid carcinoma.
  • While invasion of skeletal muscle is a more reliable feature of ETE, at the isthmus, these fibers can be normally present within the gland, and this criterion does not have value.
  • [MeSH-major] Connective Tissue / pathology. Thyroid Neoplasms / pathology
  • [MeSH-minor] Humans. Neoplasm Invasiveness. Neoplasm Staging. Prognosis. Thyroid Gland / anatomy & histology

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  • (PMID = 19949881.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 26
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16. Abdulkader M, Abercrombie J, McCulloch TA, Kaye PV: Colonic angiomyolipoma with a monotypic expression and a predominant epithelioid component. J Clin Pathol; 2005 Oct;58(10):1107-9
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  • Angiomyolipomas are rare lesions, often arising in the kidney, and are part of a group of tumours with a diverse appearance and evidence of dual melanocytic and smooth muscle differentiation known as PEComas (tumours of perivascular epithelioid cell origin).
  • This report describes an unusual case of a colonic PEComa in a 40 year old woman.
  • Unlike most of the previous colonic angiomyolipomas/PEComas reported in the literature, this case formed a large, mainly extrinsic mass and was monotypic, and composed entirely of the myomatous component with no adipose tissue or typical vasculature.
  • [MeSH-major] Angiomyolipoma / ultrastructure. Cecal Neoplasms / ultrastructure
  • [MeSH-minor] Adult. Female. Humans. Neoplasm Invasiveness

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  • [Cites] Mod Pathol. 1999 Dec;12(12):1132-6 [10619265.001]
  • [Cites] Am J Surg Pathol. 2000 Jun;24(6):889-94 [10843294.001]
  • [Cites] Mod Pathol. 2001 Jun;14(6):563-8 [11406657.001]
  • [Cites] Am J Surg Pathol. 2002 May;26(5):670-5 [11979098.001]
  • [Cites] Dis Colon Rectum. 2003 Apr;46(4):547-9 [12682553.001]
  • [Cites] Am J Gastroenterol. 1996 Sep;91(9):1852-4 [8792714.001]
  • [Cites] Z Gastroenterol. 2003 Aug;41(8):715-8 [12910425.001]
  • [Cites] Am J Surg Pathol. 2004 Feb;28(2):244-9 [15043315.001]
  • [Cites] Gastroenterol Jpn. 1989 Aug;24(4):407-9 [2777016.001]
  • [Cites] Br J Urol. 1990 Dec;66(6):585-9 [2265329.001]
  • [Cites] Minerva Chir. 1992 Aug;47(15-16):1317-9 [1407635.001]
  • [Cites] Int J Urol. 2003 May;10(5):271-3 [12694468.001]
  • (PMID = 16189161.001).
  • [ISSN] 0021-9746
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1770749
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17. Ozbudak IH, Dertsiz L, Bassorgun CI, Ozbilim G: Giant cystic chondroid hamartoma of the lung. J Pediatr Surg; 2008 Oct;43(10):1909-11
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  • Pulmonary hamartoma composed of an abnormal mixture of mesenchymal elements is the most common benign neoplasm in the lung.
  • Multilocular cystic spaces with intervening lobulated fragments of cartilaginous tissue and adipose tissue were seen.
  • Microscopically, the solid component was composed of cartilage and adipose tissue.
  • We suggest that giant cystic pulmonary hamartoma should be included in the differential diagnosis of large intrathoracic masses in children.
  • [MeSH-minor] Adipose Tissue / pathology. Calcinosis / pathology. Calcinosis / radiography. Calcinosis / surgery. Cartilage / pathology. Child. Diagnosis, Differential. Epithelium / pathology. Humans. Incidental Findings. Lung Neoplasms / diagnosis. Male. Thoracotomy. Tomography, X-Ray Computed

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  • (PMID = 18926231.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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18. Mentzel T, Toennissen J, Rütten A, Schaller J: Palmar atypical lipomatous tumour with spindle cell features (well-differentiated spindle cell liposarcoma): a rare neoplasm arising in an unusual anatomical location. Virchows Arch; 2005 Mar;446(3):300-4
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  • [Title] Palmar atypical lipomatous tumour with spindle cell features (well-differentiated spindle cell liposarcoma): a rare neoplasm arising in an unusual anatomical location.
  • Lipomatous tumours, both benign and malignant, arising on the hands are uncommon.
  • We present a rare atypical lipomatous tumour with spindle cell features (synonym: well-differentiated spindle cell liposarcoma) arising on the left palm of a 54-year-old male patient.
  • The neoplasm presented as a long-standing, exophytic neoplasm measuring 9 x 9 cm.
  • The well-circumscribed neoplasm was completely excised, and margins were tumour free.
  • Histologically, the neoplasm showed features closely resembling spindle cell lipoma, being composed of mature adipocytic cells associated with bland, neuroid spindle cells staining positively for CD34.
  • However, focally, atypia of adipocytic and stromal cells as well as scattered lipoblasts were noted, and immunohistochemical stainings showed focal overexpression of MDM 2 and CDK4.
  • Aypical lipomatous tumour with spindle cell features may arise very rarely in palmar location and has to be distinguished from a number of benign and malignant mesenchymal neoplasms.
  • [MeSH-minor] Diagnosis, Differential. Humans. Immunohistochemistry. Male. Middle Aged

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  • [Cites] Virchows Arch. 1995;427(4):353-63 [8548119.001]
  • [Cites] Mod Pathol. 2000 Nov;13(11):1192-9 [11106076.001]
  • [Cites] Am J Dermatopathol. 2000 Dec;22(6):496-502 [11190440.001]
  • [Cites] Cancer. 1975 Nov;36(5):1852-9 [1192370.001]
  • [Cites] Am J Clin Oncol. 2001 Feb;24(1):81-4 [11232956.001]
  • [Cites] Am Surg. 1975 Feb;41(2):117-20 [1122062.001]
  • [Cites] Cancer. 1981 Jan 1;47(1):126-33 [7459800.001]
  • [Cites] Genes Chromosomes Cancer. 1999 Jan;24(1):30-41 [9892106.001]
  • [Cites] Scand J Plast Reconstr Surg Hand Surg. 2000 Jun;34(2):185-7 [10900638.001]
  • [Cites] Ann Diagn Pathol. 2001 Oct;5(5):255-66 [11598853.001]
  • [Cites] Am J Surg Pathol. 1996 Oct;20(10):1182-9 [8827023.001]
  • [Cites] Acta Orthop Belg. 1994;60(3):334-5 [7992615.001]
  • [Cites] J Bone Joint Surg Am. 1994 Sep;76(9):1360-2 [8077265.001]
  • [Cites] Ann Diagn Pathol. 2000 Dec;4(6):354-60 [11149965.001]
  • [Cites] Gan No Rinsho. 1989 Feb;35(3):437-41 [2926990.001]
  • [Cites] J Hand Surg Am. 1989 Jul;14(4):700-4 [2754203.001]
  • [Cites] Ann Diagn Pathol. 2002 Apr;6(2):83-93 [12004355.001]
  • [Cites] Am J Surg Pathol. 1994 Sep;18(9):913-21 [8067512.001]
  • [Cites] Ann Plast Surg. 1983 Nov;11(5):431-3 [6651174.001]
  • [Cites] Cutis. 1987 Jul;40(1):29-32 [3665587.001]
  • [Cites] J Bone Joint Surg Am. 1965 Jun;47:727-40 [14299665.001]
  • (PMID = 15719245.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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19. Schmack I, Patel RM, Folpe AL, Wojno T, Zaldivar RA, Balzer B, Kang SJ, Weiss SW, Grossniklaus HE: Subconjunctival herniated orbital fat: A benign adipocytic lesion that may mimic pleomorphic lipoma and atypical lipomatous tumor. Am J Surg Pathol; 2007 Feb;31(2):193-8
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  • [Title] Subconjunctival herniated orbital fat: A benign adipocytic lesion that may mimic pleomorphic lipoma and atypical lipomatous tumor.
  • Over the past several years, we have seen a number of cases in which this prolapsed fat was confused pathologically with a neoplasm of adipocytic lineage, specifically pleomorphic lipoma and atypical lipomatous neoplasm (well-differentiated liposarcoma).
  • We conclude that subconjunctival herniated orbital fat commonly contains multinucleated floretlike giant cells, fibrous septae, and Lochkern cells, features that may result in diagnostic confusion with pleomorphic lipoma and atypical lipomatous neoplasms.
  • Importantly, specific diagnostic features, such as aggregates of bland spindled cells associated with wiry collagen, as seen in pleomorphic lipoma, and enlarged hyperchromatic cells within fibrous septae, as in atypical lipomatous neoplasms, are entirely absent in herniated orbital fat.
  • Multinucleated floret cells present in prolapsed orbital fat likely represent a reactive phenomenon, as they are not present in normal orbital fat.
  • [MeSH-major] Adipose Tissue / pathology. Conjunctiva / pathology. Conjunctival Diseases / pathology. Eye Neoplasms / diagnosis. Lipoma / diagnosis. Liposarcoma / diagnosis. Orbit / pathology
  • [MeSH-minor] Adipocytes / metabolism. Adipocytes / pathology. Adult. Aged. Aged, 80 and over. Biomarkers / metabolism. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Prolapse. Tomography, X-Ray Computed

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  • (PMID = 17255763.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Grant] United States / NEI NIH HHS / EY / P30-EY06360
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers
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20. Pressman G, Verma N: Pericardial fat masquerading as tumor. Echocardiography; 2010 Feb;27(2):E18-20
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  • [Title] Pericardial fat masquerading as tumor.
  • One year prior she had undergone subtotal gastrectomy and jejunostomy in treatment of a large gastrointestinal stromal tumor.
  • Two-dimensional echocardiography was performed, which showed a small circumferential pericardial effusion with a soft tissue echo density attached to the right atrial/right ventricular junction that extended over the right ventricle.
  • Because of concern about possible malignant disease, thoracoscopy and biopsy of the pericardial mass were recommended.
  • Normal fibro-adipose tissue was found with no evidence of neoplasm.
  • In this case, the concomitant presence of a small pericardial effusion and prominent fat pad at the right atrial/right ventricular junction gave the appearance of pericardial tumor.
  • [MeSH-major] Adipose Tissue / ultrasonography. Echocardiography / methods
  • [MeSH-minor] Aged. Diagnosis, Differential. False Positive Reactions. Female. Heart Neoplasms / ultrasonography. Humans

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  • (PMID = 20380671.001).
  • [ISSN] 1540-8175
  • [Journal-full-title] Echocardiography (Mount Kisco, N.Y.)
  • [ISO-abbreviation] Echocardiography
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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21. Cao DX, Wu GH, Yang ZA, Zhang B, Jiang Y, Han YS, He GD, Zhuang QL, Wang YF, Huang ZL, Xi QL: Role of beta1-adrenoceptor in increased lipolysis in cancer cachexia. Cancer Sci; 2010 Jul;101(7):1639-45
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  • Gene expressions of beta1-adrenoceptor (ADRB1), beta2-adrenoceptor (ADRB2), beta3-adrenoceptor (ADRB3), alpha2C-adrenoceptor (ADRA2C), natriuretic peptide receptor A (NPRA), insulin receptor (INSR), and HSL were determined in adipose tissues of 34 patients by real-time PCR.
  • [MeSH-major] Cachexia / physiopathology. Lipolysis / genetics. Neoplasms / genetics. Receptors, Adrenergic, beta-1 / physiology
  • [MeSH-minor] Adipose Tissue / anatomy & histology. Adipose Tissue / metabolism. Adipose Tissue / pathology. Adult. Aged. Fatty Acids, Nonesterified / metabolism. Female. G-Protein-Coupled Receptor Kinase 3 / genetics. Gastrointestinal Neoplasms / genetics. Gastrointestinal Neoplasms / surgery. Humans. Male. Middle Aged. Patient Selection. Polymerase Chain Reaction. RNA, Neoplasm / genetics. RNA, Neoplasm / isolation & purification. Receptor, Insulin / genetics. Receptors, Atrial Natriuretic Factor / genetics

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  • (PMID = 20426789.001).
  • [ISSN] 1349-7006
  • [Journal-full-title] Cancer science
  • [ISO-abbreviation] Cancer Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / ADRB1 protein, human; 0 / Fatty Acids, Nonesterified; 0 / RNA, Neoplasm; 0 / Receptors, Adrenergic, beta-1; EC 2.7.10.1 / Receptor, Insulin; EC 2.7.11.15 / ADRBK2 protein, human; EC 2.7.11.15 / G-Protein-Coupled Receptor Kinase 3; EC 4.6.1.2 / Receptors, Atrial Natriuretic Factor; EC 4.6.1.2 / atrial natriuretic factor receptor A
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22. Truong MT, Erasmus JJ, Macapinlac HA, Marom EM, Mawlawi O, Gladish GW, Sabloff BS, Bruzzi JF, Munden RF: Integrated positron emission tomography/computed tomography in patients with non-small cell lung cancer: normal variants and pitfalls. J Comput Assist Tomogr; 2005 Mar-Apr;29(2):205-9
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  • [MeSH-major] Carcinoma, Non-Small-Cell Lung / diagnosis. Image Processing, Computer-Assisted / instrumentation. Lung Neoplasms / diagnosis. Positron-Emission Tomography / instrumentation. Tomography, Spiral Computed / instrumentation
  • [MeSH-minor] Adipose Tissue, Brown / pathology. Aged. Arteriosclerosis / diagnosis. Arteriosclerosis / pathology. Artifacts. Blood Glucose / metabolism. Contrast Media / administration & dosage. Contrast Media / pharmacokinetics. Diagnosis, Differential. Diagnostic Errors. Female. Fluorodeoxyglucose F18 / pharmacokinetics. Humans. Iatrogenic Disease. Lung / pathology. Male. Middle Aged. Muscle, Skeletal / pathology. Neoplasm Staging. Reference Values. Sensitivity and Specificity

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  • (PMID = 15772538.001).
  • [ISSN] 0363-8715
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Blood Glucose; 0 / Contrast Media; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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23. Huang GS, Chang WC, Lee HS, Taylor JA, Cheng TY, Chen CY: Merkel cell carcinoma arising from the subcutaneous fat of the arm with intact skin. Dermatol Surg; 2005 Jun;31(6):717-9
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  • BACKGROUND: Merkel cell carcinoma is a rare malignant neuroendocrine neoplasm characteristically arising from the dermis of sunlight-exposed skin.
  • RESULTS: Histopathologic examination confirmed the diagnosis of Merkel cell carcinoma with local lymphatic metastasis, and the lesion was completely located in the subcutaneous fat, with no involvement of the dermis.
  • [MeSH-major] Carcinoma, Merkel Cell / diagnosis. Neoplasms, Adipose Tissue / surgery. Skin Neoplasms / diagnosis

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  • (PMID = 15996429.001).
  • [ISSN] 1076-0512
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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24. Femia A, Klein PA: Letter: Iatrogenic lipomatosis: a rare manifestation of treatment with a peroxisome proliferator-activated receptor gamma agonist. Dermatol Online J; 2010;16(4):15
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  • Lipomas are common benign neoplasms of adipose tissue.
  • [MeSH-major] Diabetes Mellitus, Type 2 / drug therapy. Hypoglycemic Agents / adverse effects. Lipoma / chemically induced. Neoplasms, Multiple Primary / chemically induced. PPAR gamma / agonists. Skin Neoplasms / chemically induced. Thiazolidinediones / adverse effects
  • [MeSH-minor] Adipose Tissue / drug effects. Aged. Female. Humans. Iatrogenic Disease

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  • (PMID = 20409422.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Hypoglycemic Agents; 0 / PPAR gamma; 0 / Thiazolidinediones; X4OV71U42S / pioglitazone
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25. Li T, Wang L, Yu HH, Sun HC, Qin LX, Ye QH, Fan J, Tang ZY: Hepatic angiomyolipoma: a retrospective study of 25 cases. Surg Today; 2008;38(6):529-35
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  • PURPOSE: We report our experience of diagnosing and treating hepatic angiomyolipoma (HAML), a rare benign mesenchymal tumor.
  • All tumors were composed of varying proportions of smooth muscle, adipose tissue, and blood vessels, and showed positive immunohistochemical staining for HMB-45.
  • The definitive diagnosis of HAML is challenging and depends on the presence of HMB-45-positive myoid cells.
  • [MeSH-major] Angiomyolipoma / diagnosis. Angiomyolipoma / surgery. Liver Neoplasms / diagnosis. Liver Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Antigens, Neoplasm / analysis. Female. Hepatectomy. Humans. Magnetic Resonance Imaging. Male. Melanoma-Specific Antigens. Middle Aged. Neoplasm Proteins / analysis. Prognosis. Retrospective Studies. Tomography, X-Ray Computed. Ultrasonography

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  • [Cites] Abdom Imaging. 2002 Mar-Apr;27(2):180-3 [11847577.001]
  • [Cites] Am J Surg Pathol. 2002 Apr;26(4):493-7 [11914628.001]
  • [Cites] Pediatr Hematol Oncol. 2005 Jan-Feb;22(1):17-24 [15770828.001]
  • [Cites] J Trauma. 2005 Sep;59(3):737-41 [16361922.001]
  • [Cites] Am J Surg Pathol. 1984 Oct;8(10):745-50 [6496843.001]
  • [Cites] J Radiol. 1995 Jan;76(1):45-50 [7861369.001]
  • [Cites] Ann Thorac Surg. 2006 Oct;82(4):1504-6 [16996965.001]
  • [Cites] J Clin Pathol. 2004 Feb;57(2):221-4 [14747459.001]
  • [Cites] Abdom Imaging. 1994 Nov-Dec;19(6):540-2 [7820028.001]
  • [Cites] Hum Pathol. 2005 Apr;36(4):341-7 [15891994.001]
  • [Cites] Chirurgie. 1994-1995;120(6-7):388-90 [7768132.001]
  • [Cites] Histopathology. 2000 May;36(5):443-50 [10792486.001]
  • [Cites] Am J Surg Pathol. 1999 Jan;23(1):34-48 [9888702.001]
  • [Cites] Hepatogastroenterology. 2005 Jul-Aug;52(64):1151-3 [16001650.001]
  • [Cites] Arch Pathol Lab Med. 1996 Jan;120(1):68-72 [8554448.001]
  • [Cites] Eur Radiol. 2001;11(8):1389-95 [11519547.001]
  • [Cites] Eur Radiol. 1997;7(3):335-7 [9087353.001]
  • [Cites] APMIS. 2004 Sep;112(9):612-6 [15601311.001]
  • [Cites] Eur J Radiol. 2002 Jan;41(1):12-8 [11750147.001]
  • [Cites] World J Gastroenterol. 2003 Aug;9(8):1856-8 [12918138.001]
  • [Cites] Acta Cytol. 2006 Jul-Aug;50(4):466-8 [16901016.001]
  • [Cites] Histopathology. 2006 Jun;48(7):831-5 [16722932.001]
  • [Cites] Emerg Radiol. 2005 Dec;12 (1-2):53-4 [16317570.001]
  • [Cites] Hum Pathol. 2006 Jun;37(6):735-41 [16733215.001]
  • [Cites] Pathol Int. 1996 Jan;46(1):24-32 [10846546.001]
  • [Cites] J Med Invest. 2005 Aug;52(3-4):218-22 [16167542.001]
  • [Cites] J Clin Pathol. 2006 Nov;59(11):1196-9 [17071805.001]
  • [Cites] Ann Chir. 2006 May;131(5):338-41 [16386232.001]
  • [Cites] Tumori. 2004 Jan-Feb;90(1):139-43 [15143988.001]
  • (PMID = 18516533.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
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26. Al-Zaid T, Alroy J, Pfannl R, Strissel KJ, Powers JF, Layer A, Carpinito G, Tischler AS: Oncocytic adrenal cortical tumor with cytoplasmic inclusions and hyaline globules. Virchows Arch; 2008 Sep;453(3):301-6
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  • [Title] Oncocytic adrenal cortical tumor with cytoplasmic inclusions and hyaline globules.
  • Adrenal cortical tumors, particularly oncocytic tumors, have been reported to contain a variety of intracytoplasmic and intramitochondrial inclusions.
  • Oncocytic cortical tumors can also morphologically mimic pheochromocytomas.
  • We report an unusual, partially oncocytic cortical neoplasm with nesting architecture, intranuclear inclusions, and hyaline globules reminiscent of pheochromocytoma, together with numerous, small, brightly eosinophilic, periodic acid-Schiff-positive cytoplasmic inclusions and typical cytoplasmic lipid droplets.
  • Immunohistochemistry and immunoblots were utilized to further characterize the tumor.
  • Immunohistochemistry demonstrated immunoreactivity of both the eosinophilic inclusions and the hyaline globules for adipose differentiation-related protein (ADRP), which is one of a group of proteins associated with storage of neutral lipids in many cell types.
  • Immunoblots confirmed the presence of ADRP and demonstrated an imbalance between ADRP and perilipin, another neutral lipid-associated protein, in tumor tissue compared to normal adrenal cortex.
  • The findings suggest that mitochondrial dysfunction in oncocytic cortical tumors may lead to abnormal processing of proteins related to the lipid-storing functions of the adrenal cortex, resulting in unusual cytoplasmic inclusions and extracellular globules resembling the globules in pheochromocytomas.
  • The finding of ADRP as a constituent of inclusions in adrenal cortical tumors has not been previously reported.
  • [MeSH-major] Adrenal Cortex Neoplasms / pathology. Inclusion Bodies / pathology. Oxyphil Cells / pathology

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  • [Cites] Histopathology. 2007 Sep;51(3):418-20 [17727488.001]
  • [Cites] Am J Clin Pathol. 1995 Oct;104(4):382-90 [7572786.001]
  • [Cites] Vet Pathol. 1974;11(2):129-37 [4375333.001]
  • [Cites] Ultrastruct Pathol. 1991 Jul-Oct;15(4-5):539-47 [1721751.001]
  • [Cites] Ultrastruct Pathol. 2002 Jul-Aug;26(4):229-35 [12227948.001]
  • [Cites] Am J Surg Pathol. 1991 Oct;15(10 ):949-56 [1928551.001]
  • [Cites] Cancer. 1970 Dec;26(6):1300-10 [5483659.001]
  • [Cites] J Biol Chem. 2005 Dec 30;280(52):42841-7 [16115879.001]
  • [Cites] Ultrastruct Pathol. 1998 Sep-Oct;22(5):357-67 [9887478.001]
  • [Cites] Ultrastruct Pathol. 1991 Jul-Oct;15(4-5):549-56 [1755111.001]
  • [Cites] J Cell Biochem. 2002;86(3):432-9 [12210750.001]
  • [Cites] Hum Pathol. 1980 Mar;11(2):205-7 [6249715.001]
  • [Cites] Am J Surg Pathol. 1998 May;22(5):603-14 [9591731.001]
  • [Cites] J Biol Chem. 2002 Aug 30;277(35):32253-7 [12077142.001]
  • [Cites] Cancer. 1992 Dec 1;70(11):2681-4 [1423199.001]
  • [Cites] J Cell Sci. 1997 Jun;110 ( Pt 12):1403-11 [9217326.001]
  • [Cites] Hinyokika Kiyo. 1986 May;32(5):757-63 [3751804.001]
  • [Cites] Physiology (Bethesda). 2006 Aug;21:233-41 [16868312.001]
  • [Cites] Virchows Arch A Pathol Anat Histopathol. 1992;421(6):533-7 [1281594.001]
  • [Cites] Ultrastruct Pathol. 1994 Jan-Apr;18(1-2):181-90 [8191624.001]
  • [Cites] Exp Clin Endocrinol Diabetes. 2007 Jun;115(6):401-4 [17701888.001]
  • [Cites] Endocrinology. 2008 Mar;149(3):942-9 [18202123.001]
  • [Cites] Endocr Pathol. 2007 Fall;18(3):187-9 [18058268.001]
  • (PMID = 18688642.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Membrane Proteins; 0 / PLIN2 protein, human; 0 / Perilipin-2
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27. Yao M, Huang Y, Shioi K, Hattori K, Murakami T, Nakaigawa N, Kishida T, Nagashima Y, Kubota Y: Expression of adipose differentiation-related protein: a predictor of cancer-specific survival in clear cell renal carcinoma. Clin Cancer Res; 2007 Jan 1;13(1):152-60
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  • [Title] Expression of adipose differentiation-related protein: a predictor of cancer-specific survival in clear cell renal carcinoma.
  • PURPOSE: We recently found that adipose differentiation-related protein (ADFP) is a potential diagnostic and prognostic biomarker for clear cell subtype renal cell carcinoma (RCC).
  • ADFP expression levels in the primary tumors and in 18 metastases were measured by real-time quantitative PCR.
  • The clinicopathologic and prognostic data were collected, as well as the von Hippel-Lindau disease (VHL) gene alteration status in selected cases.
  • RESULTS: ADFP expression was apparently high in cases without a symptomatic presentation, as well as in cases of low-stage, low-grade, or VHL alteration-positive clear cell RCC, whereas it was down-regulated in undifferentiated tumors with a spindle/pleomorphic component or metastatic lesions.
  • Further Cox multivariate analyses combined with the split-sample validation method showed that ADFP expression still remains an independent predictor for cancer-specific survival in all tumor stages and in advanced metastatic cases, whereas the predictive value of ADFP expression for cancer recurrence is rather weak.
  • CONCLUSIONS: The ADFP expression may represent the tumor differentiation status, and the detection of the expression levels provides useful prognostic information for cancer-specific survival in patients with clear cell RCC.
  • [MeSH-major] Adipose Tissue / metabolism. Carcinoma, Renal Cell / metabolism. Carcinoma, Renal Cell / mortality. Gene Expression Regulation, Neoplastic. Kidney Neoplasms / metabolism. Kidney Neoplasms / mortality. Membrane Proteins / biosynthesis. Membrane Proteins / physiology. Neoplasms / pathology
  • [MeSH-minor] Aged. Cell Differentiation. Disease Progression. Disease-Free Survival. Humans. Middle Aged. Multivariate Analysis. Neoplasm Metastasis. Prognosis. Proportional Hazards Models


28. Park CC, Rembert J, Chew K, Moore D, Kerlikowske K: High mammographic breast density is independent predictor of local but not distant recurrence after lumpectomy and radiotherapy for invasive breast cancer. Int J Radiat Oncol Biol Phys; 2009 Jan 1;73(1):75-9
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  • [Title] High mammographic breast density is independent predictor of local but not distant recurrence after lumpectomy and radiotherapy for invasive breast cancer.
  • Tissue components, including extracellular matrix, could confer resistance to ionizing radiation.
  • Fibroglandular and extracellular matrix components of breast tissue relative to adipose tissue can be quantified by the mammographic breast density (MBD), the proportion of dense area relative to the total breast area on mammography.
  • METHODS AND MATERIALS: We conducted a nested case-control study of 136 women with invasive breast cancer who had undergone BCS and RT and had had the MBD ascertained before, or at, diagnosis.
  • Women with known recurrence were matched to women without recurrence by year of diagnosis.
  • RESULTS: Patients with a high MBD (>/=75% density) vs. low (</=25%) were at increased risk of LRR (hazard ratio, 4.30; 95% confidence interval, 0.88-021.0; p = 0.071) but not distant recurrence.
  • [MeSH-major] Breast Neoplasms / epidemiology. Breast Neoplasms / radiography. Mammography / statistics & numerical data. Mastectomy, Segmental / statistics & numerical data. Neoplasm Recurrence, Local / epidemiology. Neoplasm Recurrence, Local / radiography. Radiotherapy / statistics & numerical data. Risk Assessment / methods
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Combined Modality Therapy / statistics & numerical data. Female. Humans. Lymphatic Metastasis. Middle Aged. Neoplasm Invasiveness. Prognosis. Reproducibility of Results. Risk Factors. San Francisco / epidemiology. Sensitivity and Specificity. Treatment Outcome


29. Bassett MD, Schuetze SM, Disteche C, Norwood TH, Swisshelm K, Chen X, Bruckner J, Conrad EU 3rd, Rubin BP: Deep-seated, well differentiated lipomatous tumors of the chest wall and extremities: the role of cytogenetics in classification and prognostication. Cancer; 2005 Jan 15;103(2):409-16
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  • [Title] Deep-seated, well differentiated lipomatous tumors of the chest wall and extremities: the role of cytogenetics in classification and prognostication.
  • BACKGROUND: Intramuscular lipomas and atypical lipomatous tumors (ALT) are common deep-seated lipomatous tumors of the chest wall and extremities.
  • Correct classification is important, because aggressive local disease recurrence occurs more frequently in patients with ALT than in patients with intramuscular lipoma.
  • METHODS: In the current study, 106 patients with deep-seated, well differentiated adipose tumors of the chest wall and extremities were classified as having ALT or intramuscular lipoma using a combined approach of histology and cytogenetics, if available.
  • Classification did not correlate with age and gender (P = 0.28 and P = 0.96, respectively).
  • Four percent of patients with intramuscular lipomas and 27% of patients with ALTs developed local disease recurrence (P = 0.0006).
  • Disease recurrence did not correlate with patient age at diagnosis, patient gender, tumor size, and tumor location (P = 0.45, P = 0.26, P = 0.49, and P = 0.28, respectively).
  • Within the subset of patients with ALTs, disease recurrence did not correlate with patient age at diagnosis, patient gender, or tumor location (P = 0.38, P = 0.54, and P = 0.86, respectively).
  • CONCLUSIONS: Classification of deep-seated, well differentiated lipomatous tumors of the extremities and chest wall using a combined approach of histology and cytogenetics correlated well with biologic behavior/disease recurrence.
  • [MeSH-major] Liposarcoma / genetics. Liposarcoma / pathology. Neoplasm Recurrence, Local / pathology. Soft Tissue Neoplasms / genetics. Soft Tissue Neoplasms / pathology. Thoracic Wall / pathology
  • [MeSH-minor] Adult. Age Distribution. Aged. Aged, 80 and over. Cohort Studies. Cytogenetics. Female. Humans. Immunohistochemistry. Incidence. Lower Extremity. Male. Middle Aged. Neoplasm Staging. Probability. Prognosis. Registries. Sensitivity and Specificity. Sex Distribution. Upper Extremity

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  • [Copyright] (c) 2004 American Cancer Society.
  • (PMID = 15593324.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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30. Arai S, Matsushita A, Du K, Yagi K, Okazaki Y, Kurokawa R: Novel homeodomain-interacting protein kinase family member, HIPK4, phosphorylates human p53 at serine 9. FEBS Lett; 2007 Dec 11;581(29):5649-57
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  • We describe here the cloning and characterization of a novel mouse homeodomain-interacting protein kinase (HIPK)-like gene, Hipk4.
  • Hipk4 is expressed in lung and in white adipose tissue and encodes a 616 amino acid protein that includes a serine/threonine kinase domain.
  • Human BCL2-associated X protein-promoter activity was not affected.
  • [MeSH-major] Protein-Serine-Threonine Kinases / metabolism. Serine / metabolism. Tumor Suppressor Protein p53 / metabolism
  • [MeSH-minor] Amino Acid Sequence. Animals. Catalysis. Cell Differentiation. Cell Proliferation. Cloning, Molecular. DNA, Complementary / metabolism. Humans. Inhibitor of Apoptosis Proteins. Mice. Microtubule-Associated Proteins / genetics. Microtubule-Associated Proteins / metabolism. Molecular Sequence Data. Neoplasm Proteins / genetics. Neoplasm Proteins / metabolism. Promoter Regions, Genetic. Sequence Alignment. bcl-2-Associated X Protein / genetics. bcl-2-Associated X Protein / metabolism

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  • (PMID = 18022393.001).
  • [ISSN] 0014-5793
  • [Journal-full-title] FEBS letters
  • [ISO-abbreviation] FEBS Lett.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / BAX protein, human; 0 / BIRC5 protein, human; 0 / DNA, Complementary; 0 / Inhibitor of Apoptosis Proteins; 0 / Microtubule-Associated Proteins; 0 / Neoplasm Proteins; 0 / Tumor Suppressor Protein p53; 0 / bcl-2-Associated X Protein; 452VLY9402 / Serine; EC 2.7.11.1 / HIPK4 protein, human; EC 2.7.11.1 / Protein-Serine-Threonine Kinases
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31. Witt PM, Christensen JH, Schmidt EB, Dethlefsen C, Tjønneland A, Overvad K, Ewertz M: Marine n-3 polyunsaturated fatty acids in adipose tissue and breast cancer risk: a case-cohort study from Denmark. Cancer Causes Control; 2009 Nov;20(9):1715-21
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  • [Title] Marine n-3 polyunsaturated fatty acids in adipose tissue and breast cancer risk: a case-cohort study from Denmark.
  • OBJECTIVE: The aim of this study was to investigate the association between the content of marine n-3 polyunsaturated fatty acids (PUFA) in adipose tissue, a biomarker for the long-term intake of seafood, and the subsequent development of breast cancer (BC).
  • DESIGN: We designed a case-cohort study based on a cohort of healthy Danish women, who in the 1990 s donated adipose tissue biopsies to a biobank in order to investigate the role of diet for the development of cancer and chronic disease.
  • During follow-up, incident cases of BC were identified through national registries, and the content of n-3 PUFA in adipose tissue was compared between cases and the cohort sample.
  • CONCLUSION: This study does not indicate any association between the content of total or individual marine n-3 PUFA in adipose tissue and development of BC.
  • [MeSH-major] Adipose Tissue / chemistry. Biomarkers, Tumor / analysis. Breast Neoplasms / chemistry. Fatty Acids, Omega-3 / analysis
  • [MeSH-minor] Aged. Case-Control Studies. Denmark. Female. Humans. Middle Aged. Neoplasm Staging. Risk Factors

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  • (PMID = 19711189.001).
  • [ISSN] 1573-7225
  • [Journal-full-title] Cancer causes & control : CCC
  • [ISO-abbreviation] Cancer Causes Control
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Fatty Acids, Omega-3
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32. Basten O, Bandorski D, Bismarck C, Neumann K, Fisseler-Eckhoff A: [Acetone compression. A fast, standardized method to investigate gastrointestinal lymph nodes]. Pathologe; 2010 May;31(3):218-24
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  • Lymph node staging is the most important prognostic parameter in malignant gastrointestinal tumors.
  • Manual dissection of adipose tissue is time-consuming and also depends on the experience of the individual examiner.
  • By combining elution with acetone and mechanical compression using simple equipment it was possible to completely embed adipose tissue from 404 surgical specimens (colon 348, stomach 28, greater omentum 14, other location 14) without manual dissection.
  • As a result of the procedure, the weight of the adipose tissue could be reduced by 90%-95%, making full histological examination possible.
  • Elution with acetone enables the prompt, standardized and full histological work-up of adipose tissue without manual dissection.
  • [MeSH-major] Acetone. Gastrointestinal Neoplasms / pathology. Lymph Nodes / pathology
  • [MeSH-minor] Adipose Tissue / pathology. Colonic Neoplasms / pathology. Humans. Immunohistochemistry / methods. Neoplasm Staging / methods. Prognosis. Stomach Neoplasms / pathology

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  • [Cites] Hum Pathol. 2007 May;38(5):762-7 [17306331.001]
  • [Cites] J Surg Oncol. 2002 Oct;81(2):63-9 [12355405.001]
  • [Cites] Z Gastroenterol. 2008 Aug;46(8):799-840 [18759205.001]
  • [Cites] Mod Pathol. 2004 Apr;17(4):402-6 [14976530.001]
  • [Cites] J R Soc Med. 1992 Jul;85(7):386-8 [1378498.001]
  • [Cites] Arch Surg. 1987 Nov;122(11):1253-6 [3675188.001]
  • [Cites] J Am Coll Surg. 1994 Mar;178(3):223-8 [8149012.001]
  • [Cites] J Clin Oncol. 2001 Jan 1;19(1):157-63 [11134208.001]
  • [Cites] J Natl Cancer Inst. 2007 Mar 21;99(6):433-41 [17374833.001]
  • [Cites] Dis Colon Rectum. 1994 Feb;37(2):126-8 [8306831.001]
  • [Cites] Clin Cancer Res. 1999 Aug;5(8):2065-8 [10473087.001]
  • [Cites] World J Surg. 2002 Mar;26(3):384-9 [11865379.001]
  • [Cites] Pathol Res Pract. 1982 Oct;174(4):403-11 [7155982.001]
  • [Cites] Leukemia. 2003 Dec;17(12):2257-317 [14671650.001]
  • [Cites] Ann Surg. 1980 Apr;191(4):419-29 [6989328.001]
  • [Cites] Cancer. 1990 Oct 15;66(8):1828-32 [2208038.001]
  • [Cites] Dis Colon Rectum. 1994 Apr;37(4):373-6; discussion 376-7 [8168417.001]
  • [Cites] Virchows Arch. 2003 Aug;443(2):133-8 [12844262.001]
  • [Cites] Int J Colorectal Dis. 1986 Jul;1(3):155-6 [3611943.001]
  • [Cites] Am J Surg Pathol. 2002 Feb;26(2):179-89 [11812939.001]
  • [Cites] Br J Surg. 1989 Nov;76(11):1165-7 [2688803.001]
  • [Cites] Pathologe. 2008 Jul;29(4):274-9 [17926038.001]
  • [Cites] Eur J Surg. 1994 Dec;160(12):693-7 [7888471.001]
  • [Cites] Dis Colon Rectum. 1999 Feb;42(2):143-54; discussion 154-8 [10211489.001]
  • [Cites] Dis Colon Rectum. 1992 Aug;35(8):783-8 [1644003.001]
  • [Cites] Langenbecks Arch Surg. 2006 Aug;391(4):364-8 [16683146.001]
  • [Cites] Pathologe. 2007 Jul;28(4):269-72 [17393170.001]
  • [Cites] Int J Colorectal Dis. 2009 Aug;24(8):915-21 [19387664.001]
  • (PMID = 20012620.001).
  • [ISSN] 1432-1963
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 1364PS73AF / Acetone
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33. Pakos EE, Gogou PV, Apostolikas N, Batistatou A, Tsekeris PG: Factors associated with outcome in liposarcomas of the extremities and trunk. J BUON; 2010 Jul-Sep;15(3):518-23
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  • PURPOSE: Liposarcomas are malignant tumors that arise from primitive mesenchymal cells rather than mature adipose tissue.
  • In univariate analysis factors that were significantly associated with outcomes were grade III tumors, amputation procedures, use of chemotherapy and development of local recurrences.
  • The development of metastases is observed within the first 5-years from diagnosis.
  • Metastatic disease after that period is rare.
  • The possibility of local recurrence is not negligible after the 5th year of follow up.
  • [MeSH-major] Liposarcoma / mortality. Soft Tissue Neoplasms / mortality
  • [MeSH-minor] Adult. Aged. Extremities. Female. Humans. Male. Middle Aged. Neoplasm Metastasis. Neoplasm Recurrence, Local. Proportional Hazards Models. Retrospective Studies. Risk Factors. Survival Rate

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  • (PMID = 20941821.001).
  • [ISSN] 1107-0625
  • [Journal-full-title] Journal of B.U.ON. : official journal of the Balkan Union of Oncology
  • [ISO-abbreviation] J BUON
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
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34. Kuhnen C, Mentzel T, Lehnhardt M, Homann HH, Sciot R, Debiec-Rychter M: [Lipoma and atypical lipomatous tumor within the same neoplasia: Evidence for a continuous transition]. Pathologe; 2010 Mar;31(2):129-34
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  • [Title] [Lipoma and atypical lipomatous tumor within the same neoplasia: Evidence for a continuous transition].
  • [Transliterated title] Lipom und atypischer lipomatöser Tumor innerhalb einer Neoplasie: Hinweis für einen kontinuierlichen Ubergang.
  • The case of a lipomatous tumor with a predominant lipoma component and transition to an atypical lipomatous tumor is presented.
  • A deep-seated soft tissue tumor of the right thigh with a maximum size of 14 cm was resected in a 70-year-old female patient.
  • In the remaining portion (approximately 20%) histopathology showed an atypical lipomatous tumor (ALT, lipoma-like subtype).
  • Interphase dual-color fluorescence in situ hybridization showed no amplification of the MDM 2 gene and rarely CDK4 gene amplification within the lipoma component, but high level amplification of MDM 2/CDK4 gene in the ALT area, further supporting the morphologically based diagnosis of a lipomatous tumor including areas of a true lipoma and ALT.
  • This case underlines the concept of a continuous stepwise development of lipomatous soft tissue tumors from benign to malignant counterparts as a biological continuum.
  • [MeSH-major] Cell Transformation, Neoplastic / pathology. Lipoma / pathology. Liposarcoma / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Aged. Biomarkers, Tumor / genetics. Cyclin-Dependent Kinase 4 / genetics. Female. Gene Expression Regulation, Neoplastic / genetics. Humans. In Situ Hybridization, Fluorescence. Proto-Oncogene Proteins c-mdm2 / genetics. Thigh

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  • [Cites] Int J Cancer. 1996 Sep 4;67(5):632-5 [8782650.001]
  • [Cites] Cancer. 1952 Sep;5(5):975-8 [12988186.001]
  • [Cites] Int J Cancer. 2008 May 15;122(10 ):2233-41 [18214854.001]
  • [Cites] Pathologe. 2000 Nov;21(6):441-8 [11148824.001]
  • [Cites] Int J Cancer. 2007 Jul 15;121(2):308-15 [17372913.001]
  • [Cites] Virchows Arch. 1995;427(1):19-26 [7551341.001]
  • [Cites] Verh Dtsch Ges Pathol. 1998;82:67-74 [10095419.001]
  • [Cites] Clin Cancer Res. 2009 Sep 15;15(18):5696-703 [19737942.001]
  • [Cites] Cancer Genet Cytogenet. 2001 Jul 1;128(1):24-30 [11454425.001]
  • [Cites] J Pathol. 2000 Apr;190(5):531-6 [10727978.001]
  • [Cites] Int J Oncol. 2003 Jul;23 (1):67-71 [12792777.001]
  • [Cites] Am J Surg Pathol. 1996 Nov;20(11):1361-7 [8898840.001]
  • [Cites] Mod Pathol. 2008 Aug;21(8):943-9 [18500263.001]
  • [Cites] Pathol Res Pract. 2005;201(4):347-53 [15991843.001]
  • [Cites] J Pathol. 2000 Apr;190(5):523-5 [10727976.001]
  • [Cites] Am J Surg Pathol. 2002 Oct;26(10):1319-29 [12360047.001]
  • [Cites] Am J Pathol. 1996 Feb;148(2):623-30 [8579124.001]
  • (PMID = 20063101.001).
  • [ISSN] 1432-1963
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 2.3.2.27 / MDM2 protein, human; EC 2.3.2.27 / Proto-Oncogene Proteins c-mdm2; EC 2.7.11.22 / CDK4 protein, human; EC 2.7.11.22 / Cyclin-Dependent Kinase 4
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35. Miscusi G, di Gioia CR, Patrizi G, Gravetz A, Redler A, Petrozza V: Anatomical lymph node mapping in normal mesorectal adipose tissue. Dis Colon Rectum; 2010 Dec;53(12):1640-4
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  • [Title] Anatomical lymph node mapping in normal mesorectal adipose tissue.
  • The adipose tissue was separated from the rectum and divided into 9 sections before fixing the specimen in paraffin, cutting into smaller portions, and staining with hematoxylin and eosin.
  • [MeSH-major] Adipose Tissue / anatomy & histology. Lymph Nodes / anatomy & histology. Rectum / anatomy & histology
  • [MeSH-minor] Adult. Aged. Analysis of Variance. Cadaver. Female. Humans. Lymphatic Metastasis / pathology. Male. Middle Aged. Neoplasm Staging / methods. Rectal Neoplasms / pathology. Staining and Labeling

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  • (PMID = 21178858.001).
  • [ISSN] 1530-0358
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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36. Yamaguchi T, Takimoto T, Yamashita T, Kitahara S, Omura M, Ueda Y: Fat-containing variant of solitary fibrous tumor (lipomatous hemangiopericytoma) arising on surface of kidney. Urology; 2005 Jan;65(1):175
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  • [Title] Fat-containing variant of solitary fibrous tumor (lipomatous hemangiopericytoma) arising on surface of kidney.
  • Fat-containing variant of a solitary fibrous tumor is a recently recognized benign soft-tissue tumor that usually affects the thigh and retroperitoneum.
  • We report a 51-year-old woman with a fat-containing variant of a solitary fibrous tumor that is the first reported case involving a visceral organ.
  • The tumor was well delineated and seemed to arise from the renal capsule, radiographically and macroscopically.
  • The tumor microscopically mimicked a solitary fibrous tumor but exhibited focal aggregates of fat cells.
  • A fat-containing variant of a solitary fibrous tumor involving the kidney should be distinguished from spindle cell carcinoma, angiomyolipoma, gastrointestinal stromal tumor, and cellular schwannoma.
  • [MeSH-major] Adipose Tissue / pathology. Hemangiopericytoma / pathology. Kidney Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Carcinoma, Renal Cell / diagnosis. Diagnosis, Differential. Female. Humans. Middle Aged. Nephrectomy. Tomography, X-Ray Computed

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  • (PMID = 15667897.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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37. Rose DP, Vona-Davis L: Influence of obesity on breast cancer receptor status and prognosis. Expert Rev Anticancer Ther; 2009 Aug;9(8):1091-101
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Delayed diagnosis may be one cause, but of more biological significance, especially in younger women, is the association of adiposity with estrogen receptor-negative tumors with a propensity for distant metastasis.
  • After the menopause, the major mechanism for the relationship is the elevated estrogen synthesis by adipose tissue; these hormone-dependent tumors are estrogen receptor-positive.
  • Weight control is important, not only to target breast cancer progression, but also to reduce the risk of nonbreast cancer mortality risk associated with excess adiposity.
  • [MeSH-major] Breast Neoplasms / complications. Obesity / complications. Receptors, Estrogen / metabolism
  • [MeSH-minor] Adipose Tissue / metabolism. Disease Progression. Estrogens / biosynthesis. Female. Humans. Menopause / metabolism. Neoplasm Metastasis. Neovascularization, Pathologic / physiopathology. Prognosis

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  • (PMID = 19671029.001).
  • [ISSN] 1744-8328
  • [Journal-full-title] Expert review of anticancer therapy
  • [ISO-abbreviation] Expert Rev Anticancer Ther
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Estrogens; 0 / Receptors, Estrogen
  • [Number-of-references] 71
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38. Takeshita N, Noie T, Otsuka Y, Hoshino A, Nara S, Ito K, Harihara Y, Furushima K, Konishi T: Fat replacement of the distal pancreas in a case of advanced gastric cancer. Int Surg; 2010 Jul-Sep;95(3):261-4
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  • Histopathologic examination of the resected pancreas revealed the absence of lobules, acini, conduits, and pancreatic ducts, with only islets of Langerhans found scattered in the adipose tissue.
  • In patients with fat-replaced pancreas, preoperative evaluation of direct invasion of adjacent organs/tissues by gastric cancer is difficult.
  • [MeSH-major] Adipose Tissue / pathology. Pancreas / pathology. Stomach Neoplasms / pathology
  • [MeSH-minor] Aged. Atrophy. Endoscopy, Gastrointestinal. Gastrectomy. Humans. Liver / pathology. Liver / radiography. Male. Neoplasm Invasiveness. Pancreatectomy. Splenectomy. Tomography, X-Ray Computed

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  • (PMID = 21067007.001).
  • [ISSN] 0020-8868
  • [Journal-full-title] International surgery
  • [ISO-abbreviation] Int Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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39. Xu Y, Wang N, Ling F, Li P, Gao Y: Receptor for activated C-kinase 1, a novel binding partner of adiponectin receptor 1. Biochem Biophys Res Commun; 2009 Jan 2;378(1):95-8
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  • Adiponectin is an adipose tissue derived hormone with anti-diabetic and insulin-sensitizing properties.
  • [MeSH-major] GTP-Binding Proteins / metabolism. Neoplasm Proteins / metabolism. Receptors, Adiponectin / metabolism. Receptors, Cell Surface / metabolism

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  • (PMID = 19010305.001).
  • [ISSN] 1090-2104
  • [Journal-full-title] Biochemical and biophysical research communications
  • [ISO-abbreviation] Biochem. Biophys. Res. Commun.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / ADIPOR1 protein, human; 0 / Adiponectin; 0 / GNB2L1 protein, human; 0 / Neoplasm Proteins; 0 / Receptors, Adiponectin; 0 / Receptors, Cell Surface; EC 3.6.1.- / GTP-Binding Proteins; IY9XDZ35W2 / Glucose
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40. Dell'Avanzato R, Castaldi F, Giovannini C, Mercadante E, Cianciulli P, Carlini M: Giant symptomatic myelolipoma of the right adrenal gland: a case report. Chir Ital; 2009 Mar-Apr;61(2):231-6
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  • Adrenal myelolipoma is an uncommon tumour of the adrenal gland, usually unilateral, frequently associated with hypertension and obesity, with a benign biological behaviour and without hormonal activity, first described in 1905.
  • The neoplasm consists of adipose tissue and myelopoietic cells of the bone marrow.
  • These tumours have a very slow but continued growth and their volume and weight vary significantly from small lesions of a few grams to huge masses weighing up to several kilograms.
  • In this report a case of a 43-year-old male with a 22 x 18 x 9 cm giant myelolipoma, weighing 3500 g and originating from the right adrenal gland is described.
  • The different aetiological hypotheses of this rare neoplasm and its clinical features, diagnosis and treatment are discussed.
  • [MeSH-major] Adrenal Cortex Neoplasms / pathology. Myelolipoma / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Male. Treatment Outcome

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  • (PMID = 19536999.001).
  • [ISSN] 0009-4773
  • [Journal-full-title] Chirurgia italiana
  • [ISO-abbreviation] Chir Ital
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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41. Nilsson M, Domanski H, Mertens F, Mandahl N: Atypical lipomatous tumor with rare structural rearrangements involving chromosomes 8 and 12. Oncol Rep; 2005 Apr;13(4):649-52
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  • [Title] Atypical lipomatous tumor with rare structural rearrangements involving chromosomes 8 and 12.
  • Atypical lipomatous tumor (ALT), an intermediate malignant neoplasm of soft tissues, is characterized by the presence of supernumerary ring and giant marker chromosomes.
  • The complex rearrangement was not only the result of multiple breaks and reunions of these chromosomes, but was also associated with a gain of chromosome 12 sequences.
  • Whether ALTs with these types of aberrations have a lower risk of tumor progression than ALTs with the notoriously mitotically unstable ring and giant marker chromosomes remains to be investigated.
  • [MeSH-major] Chromosome Aberrations. Chromosomes, Human, Pair 12. Chromosomes, Human, Pair 8. Lipoma / genetics. Lipoma / pathology. Neoplasms, Adipose Tissue / genetics. Neoplasms, Adipose Tissue / pathology
  • [MeSH-minor] Biopsy. Chromosome Banding. Chromosomes / ultrastructure. Disease Progression. Female. Humans. In Situ Hybridization, Fluorescence. Interphase. Karyotyping. Middle Aged. Phenotype

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  • (PMID = 15756437.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
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42. Bandyopadhyay S, Basturk O, Coban I, Thirabanjasak D, Liang H, Altinel D, Adsay NV: Isolated solitary ducts (naked ducts) in adipose tissue: a specific but underappreciated finding of pancreatic adenocarcinoma and one of the potential reasons of understaging and high recurrence rate. Am J Surg Pathol; 2009 Mar;33(3):425-9
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  • [Title] Isolated solitary ducts (naked ducts) in adipose tissue: a specific but underappreciated finding of pancreatic adenocarcinoma and one of the potential reasons of understaging and high recurrence rate.
  • We recently noted isolated solitary ductal units (ISDs) in adipose tissue to be a reliable indicator of adenocarcinoma.
  • ISD was defined as a solitary gland lying individually in adipose tissue, either directly abutting adipocytes or separated from them by only a thin rim of fibromuscular tissue.
  • ISD was detected in 50/105 (47.6%) of pancreatic resections for ductal adenocarcinoma, but not in any resections with chronic pancreatitis only (specificity 100%; sensitivity 47.6%).
  • ISDs were often located in histologic sections taken for the evaluation of the retroperitoneal margin and pancreatic-free surfaces where adipose tissue is more abundant.
  • In conclusion, ISD lying in adipose tissue unaccompanied by other elements, present in 47.6% of pancreatic resections when peripancreatic soft tissues away from the tumor are sampled, is a very specific finding for carcinoma that may be instrumental in the diagnosis and staging of carcinoma as well as margin evaluation.
  • [MeSH-major] Adipose Tissue / pathology. Carcinoma, Pancreatic Ductal / pathology. Pancreatic Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans. Neoplasm Recurrence, Local / pathology. Neoplasm Staging. Pancreatitis / pathology

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  • (PMID = 19092633.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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43. Arikawa S, Uchida M, Shinagawa M, Tohnan T, Hayabuchi N: Significance of the " beak sign"in the differential diagnosis of uterine lipoleiomyoma from ovarian dermoid cyst. Kurume Med J; 2006;53(1-2):37-40
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  • [Title] Significance of the " beak sign"in the differential diagnosis of uterine lipoleiomyoma from ovarian dermoid cyst.
  • Although a series of imaging studies suggested a lipomatous tumor, diagnosis was difficult because the tumor appeared as a pedunculated mass extending from the uterine body.
  • To distinguish the tumor from an ovarian lipomatous tumor, the "beak sign" in a magnetic resonance imaging study was diagnostic in this case.
  • The purpose of this paper is to review lipomatous masses of the female pelvis, to discuss the differential diagnosis of the unusual imaging features, and to discuss imaging techniques to optimize pelvic mass characterization.
  • [MeSH-major] Leiomyoma / diagnosis. Lipoma / diagnosis. Ovarian Cysts / diagnosis. Uterine Neoplasms / diagnosis
  • [MeSH-minor] Aged. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Tomography, X-Ray Computed

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  • (PMID = 17043394.001).
  • [ISSN] 0023-5679
  • [Journal-full-title] The Kurume medical journal
  • [ISO-abbreviation] Kurume Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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44. Fitzhugh VA, Kim SA, Borcich A, Zhu H, Wu M, Szporn AH, Chen H: Metastatic hepatocellular carcinoma presenting as a pancreatic mass by computed tomography scan and mimicking a primary neuroendocrine tumor: a potential pitfall in aspiration cytology. Diagn Cytopathol; 2009 Dec;37(12):915-9
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  • [Title] Metastatic hepatocellular carcinoma presenting as a pancreatic mass by computed tomography scan and mimicking a primary neuroendocrine tumor: a potential pitfall in aspiration cytology.
  • Hepatocellular carcinoma (HCC) is a highly malignant neoplasm, often presenting at late stage and portending a poor prognosis for the patient.
  • The peripancreatic fat is a rare site of extrahepatic metastasis, and metastatic HCC can mimic primary pancreatic neoplasms, even in this location.
  • It is crucial to be aware of this pitfall in the evaluation of aspiration cytology of pancreatic neoplasms and to develop a strategy to reach the correct diagnosis.
  • We present an endoscopic ultrasound fine-needle aspiration diagnosis of metastatic HCC presenting as a pancreatic mass radiologically that had neuroendocrine features on various cytological and histological preparations.
  • The metastatic lesions were located surgically in the peripancreatic adipose tissue with involvement of one peripancreatic lymph node.
  • This case illustrates the utility of FNA for diagnosing uncommon presentations of HCC and the importance of clinical history, cell block, and an immunocytochemical panel in determining the origin of the tumor.
  • [MeSH-major] Biopsy, Needle. Carcinoma, Hepatocellular / secondary. Liver Neoplasms / pathology. Neuroendocrine Tumors / radiography. Pancreatic Neoplasms / secondary
  • [MeSH-minor] Animals. Biomarkers, Tumor / analysis. Diagnosis, Differential. Humans. Immunohistochemistry. Male. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 19582809.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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45. Ma L, Kowalski D, Javed K, Hui P: Atypical angiomyolipoma of kidney in a patient with tuberous sclerosis: a case report with p53 gene mutation analysis. Arch Pathol Lab Med; 2005 May;129(5):676-9
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  • Angiomyolipoma (AML) is the most common benign mesenchymal tumor of the kidney.
  • It belongs to the family of perivascular epithelioid cell tumors and is typically composed of blood vessels, adipose tissue, and smooth muscle- like cells, which are characteristically positive for HMB-45.
  • The tumor consisted of mostly epithelioid cells with marked nuclear pleomorphism and frequent mitoses and was positive for HMB-45.
  • The diagnosis of atypical epithelioid AML was made.
  • Codon alteration in the p53 gene was not detected, despite focal p53 immunoreactivity and single nucleotide polymorphism at exon 6.
  • Our finding indicates no definite link between p53 abnormalities and the atypical appearance of AML.
  • [MeSH-major] Angiomyolipoma / pathology. Genes, p53. Kidney Neoplasms / pathology. Mutation. Tuberous Sclerosis / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Cytoplasm / ultrastructure. DNA Mutational Analysis. DNA, Neoplasm / genetics. Female. Humans. Immunohistochemistry. Intercellular Junctions / ultrastructure. Nephrectomy. Polymerase Chain Reaction. Polymorphism, Single-Stranded Conformational. Treatment Outcome


46. Murphy RA, Wilke MS, Perrine M, Pawlowicz M, Mourtzakis M, Lieffers JR, Maneshgar M, Bruera E, Clandinin MT, Baracos VE, Mazurak VC: Loss of adipose tissue and plasma phospholipids: relationship to survival in advanced cancer patients. Clin Nutr; 2010 Aug;29(4):482-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Loss of adipose tissue and plasma phospholipids: relationship to survival in advanced cancer patients.
  • BACKGROUND & AIMS: Extensive loss of adipose tissue is a key feature of cancer cachexia.
  • It is not known whether these processes coincide across the cancer trajectory nor has their relationship with survival been defined.
  • Changes in adipose tissue mass and plasma phospholipids were characterized within 500days prior to death and prognostic significance assessed.
  • METHODS: Adipose tissue rate of change was determined in a retrospective cohort of patients who died of colorectal and lung cancers (n=108) and who underwent >2 computed tomography scans in the last 500days of life.
  • Plasma phospholipid fatty acids were measured prospectively in a similar cohort of patients with metastatic cancer (n=72).
  • RESULTS: Accelerated loss of adipose tissue begins at 7months from death reaching an average loss of 29% of total AT 2months from death.
  • Plasma phospholipid fatty acids were 35% lower in patients closest to death versus those surviving >8months.
  • Losses of phospholipid fatty acids and adipose tissue occur in tandem and are predictive of survival.
  • CONCLUSIONS: Depletion of plasma phospholipids likely indicates a deficit of essential fatty acids in the periphery which may contribute to loss of adipose tissue.
  • [MeSH-major] Adipose Tissue, White / metabolism. Adiposity. Cachexia / metabolism. Lipolysis. Neoplasms / physiopathology. Phospholipids / blood
  • [MeSH-minor] Aged. Cohort Studies. Disease Progression. Fatty Acids / blood. Female. Humans. Intra-Abdominal Fat / metabolism. Male. Middle Aged. Muscle, Skeletal / metabolism. Neoplasm Metastasis. Prognosis. Retrospective Studies. Subcutaneous Fat / metabolism. Survival Analysis

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  • [Copyright] Copyright 2009 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.
  • (PMID = 19959263.001).
  • [ISSN] 1532-1983
  • [Journal-full-title] Clinical nutrition (Edinburgh, Scotland)
  • [ISO-abbreviation] Clin Nutr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Fatty Acids; 0 / Phospholipids
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47. Hameed M, Clarke K, Amer HZ, Mahmet K, Aisner S: Cellular angiofibroma is genetically similar to spindle cell lipoma: a case report. Cancer Genet Cytogenet; 2007 Sep;177(2):131-4
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  • Cellular angiofibroma is a benign mesenchymal neoplasm of female and male genital tract composed of prominent vasculature and stromal spindle cells, often with admixture of adipose tissue.
  • The tumor has histomorphologic similarities to angiomyofibroblastoma and spindle cell lipoma.
  • Herein we describe a tumor arising in the perineal region of a 60-year-old man with morphological and immunohistochemical features of cellular angiofibroma and showing cytogenetic characteristics similar to spindle cell lipoma.

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  • (PMID = 17854668.001).
  • [ISSN] 0165-4608
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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48. Kondi-Pafiti A, Grapsa D, Kairi-Vassilatou E, Kontogianni-Katsarou K, Koliopoulos C, Botsis D: Mesenchymal tumors of the uterine corpus with heterologous and hematopoietic components: a study of ten cases and review of the literature. Eur J Gynaecol Oncol; 2006;27(1):73-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mesenchymal tumors of the uterine corpus with heterologous and hematopoietic components: a study of ten cases and review of the literature.
  • OBJECTIVE: To study the histopathological features of mesenchymal tumors of the uterine corpus with heterologous and hematopoietic components, and review their histogenesis and differential diagnosis from other neoplastic and non-neoplastic lesions.
  • METHODS: Ten cases of mesenchymal tumors of the uterine corpus, massively infiltrated by hematopoioetic cells, or composed of other benign heterologous elements (adipose tissue in the present cases) were retrieved from the archival files of our laboratory and studied histopathologically.
  • RESULTS: Six of our studied cases were diagnosed as leiomyomas, two as lipoleiomyomas, one as a symplastic lipoleiomyoma, and one as an endometrial stromal tumor.
  • Immunohistochemical study of the leiomyomas with massive lymphocytic infiltration revealed the presence of a predominantly B-cell population within the infiltrate, which was polyclonal in nature.
  • The endometrial stromal tumor was severely infiltrated by histiocytes, and was positive for vimentin, CD10, PgR and negative for actin, desmin, ER and caldesmon.
  • CONCLUSION: The presence of hematopoietic or heterologous elements within an otherwise bland uterine leiomyoma or endometrial stromal tumor may give rise to diagnostic difficulties.
  • Regularity of the tumor margins, low mitotic activity and absence of nuclear atypia or necrosis should be established for the exclusion of a malignancy.
  • In the presence of massive lymphocytic infiltration of a leiomyoma the clonality of the infiltrate may aid in differentiating it from a malignant lymphoma.
  • The pathogenesis and clinical significance of these rare neoplasms remain to be clarified.
  • [MeSH-major] Endometrial Stromal Tumors / pathology. Leiomyoma / pathology. Mesoderm / pathology. Uterine Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Biopsy, Needle. Disease Progression. Female. Hematopoietic System / pathology. Humans. Immunohistochemistry. Middle Aged. Neoplasm Staging. Prognosis. Registries. Retrospective Studies. Risk Assessment

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  • (PMID = 16550975.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 37
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49. Adachi S, Kawamura N, Hatano K, Kakuta Y, Takada T, Hara T, Yamaguchi S: Lipomatous ganglioneuroma of the retroperitoneum. Pathol Int; 2008 Mar;58(3):183-6
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  • [Title] Lipomatous ganglioneuroma of the retroperitoneum.
  • A unique case of ganglioneuroma mimicking a lipomatous tumor in a 73-year-old man is reported.
  • The tumor was incidentally found on radiography performed for unrelated reasons.
  • The laparotomy indicated that the tumor was located on the right adrenal gland.
  • It was well circumscribed but not encapsulated, and was approximately 2 cm in diameter.
  • Microscopically, ganglioneuromatous component was scattered in the background of a large amount of adipose tissue.
  • Because the presence of such a large amount of adipose tissue seems to be rare in ganglioneuromas, its histogenesis is discussed.
  • [MeSH-major] Adipose Tissue / pathology. Ganglioneuroma / diagnosis. Myelolipoma / diagnosis. Retroperitoneal Neoplasms / diagnosis
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Chromogranins / analysis. Diagnosis, Differential. Glial Fibrillary Acidic Protein / analysis. Humans. Immunohistochemistry. Male. S100 Proteins / analysis. Synaptophysin / analysis

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  • (PMID = 18251782.001).
  • [ISSN] 1440-1827
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Chromogranins; 0 / Glial Fibrillary Acidic Protein; 0 / S100 Proteins; 0 / Synaptophysin
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50. Davis CJ, Barton JH, Sesterhenn IA: Cystic angiomyolipoma of the kidney: a clinicopathologic description of 11 cases. Mod Pathol; 2006 May;19(5):669-74
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  • This report deals with 11 examples of renal angiomyolipomas (AML) which appear to include an epithelial element as a part of the neoplasm in the form of gross or microscopic cysts-usually both.
  • Three of these were known to be symptomatic: intermittent flank pain and gross hematuria for 2 months; recurrent hematuria both before and after flank trauma and a third patient with acute abdomen due to a ruptured tumor blood vessel.
  • Seven tumors were in the right kidney and four in the left.
  • Microscopically, virtually all of the tumors included multiple smaller cysts and these were lined by flat, cuboidal or columnar epithelium and occasionally hobnail epithelium.
  • There was usually a subepithelial collar of poorly differentiated cells, but the solid element of all tumors was myomatous angiomyolipoma; only one case had any adipose tissue.
  • Immunohistochemically, all tumors tested were reactive with actin, desmin and HMB-45, with the latter being more intensely positive in the subepithelial collars.
  • [MeSH-major] Angiomyolipoma / pathology. Cysts / pathology. Kidney Neoplasms / pathology
  • [MeSH-minor] Actins / analysis. Adult. Aged. Antigens, Neoplasm. Desmin / analysis. Female. Humans. Immunohistochemistry. MART-1 Antigen. Male. Melanoma-Specific Antigens. Middle Aged. Muscle, Smooth / chemistry. Neoplasm Proteins / analysis. Receptors, Estrogen / analysis. Receptors, Progesterone / analysis

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  • (PMID = 16528375.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, Neoplasm; 0 / Desmin; 0 / MART-1 Antigen; 0 / MLANA protein, human; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
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51. Hooper CC: Teratoma in the cerebrum of a fantail pigeon. Avian Pathol; 2008 Apr;37(2):141-3
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  • [Title] Teratoma in the cerebrum of a fantail pigeon.
  • This is the first report of a primary teratoma in the cerebral cortex of a 1-year-old fantail pigeon and one of the few reports of intracranial teratomas in birds.
  • The right cerebral hemisphere contained an unencapsulated teratoma that included adipose, cartilaginous, fibrous and undifferentiated mesenchymal tissue as well as keratinized and glandular epithelial structures.
  • Immunohistochemistry designed for mammals proved very useful and has been used to investigate the two germ cell lines, epithelial and mesenchymal, detected in the neoplasm.
  • Neuron-specific enolase immunoreactivity was strongly positive in the normal brain adjacent to the neoplasm but there was no immunoreactivity within the neoplasm.
  • Also, there was no S-100 immunoreactivity, suggesting that the mammalian proteins on which the immunohistochemistry is based are not present in pigeons.
  • [MeSH-major] Bird Diseases / pathology. Brain Neoplasms / veterinary. Columbidae. Teratoma / veterinary

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  • (PMID = 18393091.001).
  • [ISSN] 1465-3338
  • [Journal-full-title] Avian pathology : journal of the W.V.P.A
  • [ISO-abbreviation] Avian Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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52. Tanaka K, Urata N, Mikami M, Ogasawara M, Matsunaga T, Terashima N, Suzuki H: Effect of iguratimod and other anti-rheumatic drugs on adenocarcinoma colon 26-induced cachexia in mice. Inflamm Res; 2007 Jan;56(1):17-23
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  • Serum biochemical parameters and wasting of adipose tissue and muscle were evaluated as the nutritional condition in tumor-bearing mice at day 14.
  • Interleukin-6 (IL-6) levels in serum and tumor tissue of those mice were also quantified.
  • RESULTS: Administration of T-614 did not inhibit the tumor growth, but it resulted in attenuation of cachexia symptoms, such as the reduction in epididymal fat and gastrocnemius muscle, and the decrease of serum albumin.
  • Furthermore, T-614 decreased the serum levels of IL-6, and reduced its gene expression in the tumor tissues.
  • Exogenously administered IL-6 nullified the suppressive effect of T-614.
  • Prednisolone prevented the weight loss and the wasting without inhibiting tumor growth.
  • Methotrexate and indomethacin did not exert any preferable effects in a therapeutic dosing schedule.
  • CONCLUSIONS: Our results demonstrate that T-614 exerts an anticachectic effect in tumor-bearing mice through the inhibition of IL-6 gene expression.
  • [MeSH-major] Adenocarcinoma / complications. Antirheumatic Agents / therapeutic use. Cachexia / drug therapy. Cachexia / etiology. Chromones / therapeutic use. Colonic Neoplasms / complications. Sulfonamides / therapeutic use
  • [MeSH-minor] Adipose Tissue / pathology. Animals. Blood Glucose / metabolism. Body Weight / drug effects. Cholesterol / blood. Eating / drug effects. Interleukin-6 / biosynthesis. Interleukin-6 / genetics. Male. Mice. Mice, Inbred BALB C. Muscle, Skeletal / pathology. Neoplasm Transplantation. Organ Size / drug effects. RNA, Messenger / biosynthesis. RNA, Messenger / genetics

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  • (PMID = 17334666.001).
  • [ISSN] 1023-3830
  • [Journal-full-title] Inflammation research : official journal of the European Histamine Research Society ... [et al.]
  • [ISO-abbreviation] Inflamm. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Antirheumatic Agents; 0 / Blood Glucose; 0 / Chromones; 0 / Interleukin-6; 0 / RNA, Messenger; 0 / Sulfonamides; 4IHY34Y2NV / iguratimod; 97C5T2UQ7J / Cholesterol
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53. Kucerova L, Matuskova M, Pastorakova A, Tyciakova S, Jakubikova J, Bohovic R, Altanerova V, Altaner C: Cytosine deaminase expressing human mesenchymal stem cells mediated tumour regression in melanoma bearing mice. J Gene Med; 2008 Oct;10(10):1071-82
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  • [Title] Cytosine deaminase expressing human mesenchymal stem cells mediated tumour regression in melanoma bearing mice.
  • BACKGROUND: Previously, we validated capability of human adipose tissue-derived mesenchymal stem cells (AT-MSC) to serve as cellular vehicles for gene-directed enzyme prodrug molecular chemotherapy.
  • We aimed to determine the cytotoxic efficiency to other tumour cells both in vitro and in vivo.
  • METHODS: CD y-AT-MSC/5FC-mediated proliferation inhibition against a panel of human tumour cells lines was evaluated in direct and indirect cocultures in vitro.
  • Complete regression in 89% of tumours was achieved when 20% CD y-AT-MSC/5FC were co-injected along with tumour cells.
  • More importantly, systemic CD y-AT-MSC administration resulted in therapeutic cell homing into subcutaneous melanoma and mediated tumour growth inhibition.
  • [MeSH-minor] Adipose Tissue / metabolism. Adult. Animals. Apoptosis. Cancer Vaccines / genetics. Cell Line, Tumor. Flucytosine / metabolism. Flucytosine / pharmacology. Genetic Therapy. Genetic Vectors / administration & dosage. Humans. Mice. Mice, Nude. Neoplasm Transplantation. Pentosyltransferases / genetics. Pentosyltransferases / metabolism. Prodrugs / pharmacology. Recombinant Fusion Proteins / genetics. Recombinant Fusion Proteins / metabolism. Transduction, Genetic

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  • [Copyright] Copyright (c) 2008 John Wiley & Sons, Ltd.
  • (PMID = 18671316.001).
  • [ISSN] 1521-2254
  • [Journal-full-title] The journal of gene medicine
  • [ISO-abbreviation] J Gene Med
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Cancer Vaccines; 0 / Prodrugs; 0 / Recombinant Fusion Proteins; D83282DT06 / Flucytosine; EC 2.4.2.- / Pentosyltransferases; EC 2.4.2.9 / uracil phosphoribosyltransferase; EC 3.5.4.1 / Cytosine Deaminase
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54. Muehlberg FL, Song YH, Krohn A, Pinilla SP, Droll LH, Leng X, Seidensticker M, Ricke J, Altman AM, Devarajan E, Liu W, Arlinghaus RB, Alt EU: Tissue-resident stem cells promote breast cancer growth and metastasis. Carcinogenesis; 2009 Apr;30(4):589-97
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tissue-resident stem cells promote breast cancer growth and metastasis.
  • Mesenchymal stem cells derived from bone marrow have recently been described to localize to breast carcinomas and to integrate into the tumor-associated stroma.
  • In the present study, we investigated whether adipose tissue-derived stem cells (ASCs) could play a role in tumor growth and invasion.
  • Compared with bone marrow-derived cells, ASCs as tissue-resident stem cells are locally adjacent to breast cancer cells and may interact with tumor cells directly.
  • The tumor-promoting effect of ASCs was abolished by knockdown of the chemokine C-X-C receptor 4 in 4T1 tumor cells.
  • We demonstrated that ASCs home to tumor site and promote tumor growth not only when co-injected locally but also when injected intravenously.
  • Furthermore, we demonstrated that ASCs incorporate into tumor vessels and differentiate into endothelial cells.
  • The tumor-promoting effect of tissue-resident stem cells was also tested and validated using a human breast cancer line MDA-MB-231 cells and human adipose tissue-derived stem cells.
  • Our findings indicate that the interaction of local tissue-resident stem cells with tumor stem cells plays an important role in tumor growth and metastasis.
  • [MeSH-major] Lung Neoplasms / secondary. Mammary Neoplasms, Animal / pathology. Neoplastic Stem Cells / metabolism
  • [MeSH-minor] Adipose Tissue / metabolism. Adipose Tissue / pathology. Animals. Blotting, Western. Cell Movement. Chemokine CXCL12 / metabolism. Enzyme-Linked Immunosorbent Assay. Flow Cytometry. Immunoprecipitation. Male. Mice. Mice, Inbred BALB C. Mice, Nude. Neoplasm Invasiveness. Neovascularization, Pathologic. Receptors, CXCR4 / antagonists & inhibitors. Receptors, CXCR4 / genetics. Receptors, CXCR4 / metabolism. Spheroids, Cellular. Stromal Cells / cytology. Stromal Cells / metabolism. Vascular Endothelial Growth Factor A / metabolism

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  • (PMID = 19181699.001).
  • [ISSN] 1460-2180
  • [Journal-full-title] Carcinogenesis
  • [ISO-abbreviation] Carcinogenesis
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Chemokine CXCL12; 0 / Receptors, CXCR4; 0 / Vascular Endothelial Growth Factor A
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55. Pedemonte JG, Degiovanni D, Pusterla D, Reibel C, Di Nucci J, Boccio C, Degiovanni R, Dotta A: [Angiomyolipoma and Lenk syndrome: case report]. Actas Urol Esp; 2008 Sep;32(8):850-4
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  • [Transliterated title] Triada de Lenk como presentación clínica del angiomiolipoma.
  • Angiomyolipoma (AML) is a benign clonal neoplasm that consists of varying amounts of mature adipose tissue, smooth muscle, and thick-walled vessels.
  • Approximately 20% of AMLs are found in patients with tuberous sclerosis syndrome (TS), an autosomal-dominant disorder characterized by mental retardation, epilepsy, and adenoma sebaceous, a distinctive skin lesion.
  • Intervention should be considered for larger tumors, particularly if the patient is symptomatic, taking into account patient age, comorbidities, and other related factors.
  • We present the case of a fifty-nine-year old patient with an angiomyolipoma and massive retroperitoneal hemorrhage with Lenk syndrome.
  • [MeSH-major] Angiomyolipoma / complications. Flank Pain / complications. Hematuria / complications. Kidney Diseases / complications. Kidney Neoplasms / complications

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  • (PMID = 19013986.001).
  • [ISSN] 0210-4806
  • [Journal-full-title] Actas urologicas espanolas
  • [ISO-abbreviation] Actas Urol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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56. Asp ML, Tian M, Wendel AA, Belury MA: Evidence for the contribution of insulin resistance to the development of cachexia in tumor-bearing mice. Int J Cancer; 2010 Feb 1;126(3):756-63
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  • [Title] Evidence for the contribution of insulin resistance to the development of cachexia in tumor-bearing mice.
  • Cancer cachexia is a syndrome of unintentional weight loss that is characterized by wasting of both skeletal muscle and adipose tissue.
  • In the present study, male CD2F1 mice with colon-26 adenocarcinoma tumors underwent an insulin tolerance test before the onset of weight loss.
  • Compared to mice without tumors, mice with tumors had a profoundly blunted blood glucose response to insulin.
  • Corroborating these findings, mice with tumors had decreased phosphorylation of Akt in quadriceps muscle and epididymal adipose tissue at the end of the study.
  • Rosiglitazone treatment increased serum adiponectin, insulin sensitivity, and body weight, and decreased Atrogin-1 and MuRF-1 expression in the skeletal muscle of tumor-bearing mice.
  • In conclusion, insulin resistance is an early event in mice with cachexia induced by colon-26 tumors.
  • These data provide evidence that insulin resistance is not only present in cachexia, but also has a role in cachexia pathogenesis.
  • [MeSH-major] Adenocarcinoma / physiopathology. Cachexia / physiopathology. Colonic Neoplasms / physiopathology. Insulin Resistance
  • [MeSH-minor] Adiponectin / blood. Animals. Autophagy. Blood Glucose / analysis. Crosses, Genetic. Insulin. Male. Mice. Mice, Inbred BALB C. Mice, Inbred DBA. Muscle, Skeletal / metabolism. Muscle, Skeletal / pathology. Muscular Atrophy / etiology. Muscular Atrophy / physiopathology. Neoplasm Proteins / analysis. Proteasome Endopeptidase Complex / metabolism. Proto-Oncogene Proteins c-akt / analysis. Random Allocation. Thiazolidinediones / therapeutic use. Weight Loss

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  • (PMID = 19634137.001).
  • [ISSN] 1097-0215
  • [Journal-full-title] International journal of cancer
  • [ISO-abbreviation] Int. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Adiponectin; 0 / Adipoq protein, mouse; 0 / Blood Glucose; 0 / Insulin; 0 / Neoplasm Proteins; 0 / Thiazolidinediones; 05V02F2KDG / rosiglitazone; EC 2.7.11.1 / Akt1 protein, mouse; EC 2.7.11.1 / Proto-Oncogene Proteins c-akt; EC 3.4.25.1 / Proteasome Endopeptidase Complex
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57. Sagan D, Zdunek M, Korobowicz E: Primary myelolipoma of the chest wall. Ann Thorac Surg; 2009 Oct;88(4):e39-41
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  • Myelolipoma is a rare neoplasm composed of an admixture of mature adipose tissue and hematopoietic elements.
  • We present a 63-year-old man with an accidentally detected tumor of the chest wall.
  • Thoracoscopic resection and subsequent histopathologic examination of the lesion revealed myelolipoma with bony spicules, which are an unusual component in this neoplasm.
  • We discuss the etiology, histopathology, differential diagnosis, and recommended management of extra-adrenal myelolipoma, and we conclude that it should be considered in the differential diagnosis of subpleural chest wall tumors.
  • [MeSH-major] Lung Neoplasms / diagnosis. Myelolipoma / diagnosis. Pneumonectomy / methods
  • [MeSH-minor] Diagnosis, Differential. Follow-Up Studies. Humans. Male. Middle Aged. Thoracoscopy. Tomography, X-Ray Computed

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  • (PMID = 19766776.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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58. Joshi A, Shah V, Varma M: Intraprostatic fat in a prostatic needle biopsy: a case report and review of the literature. Histopathology; 2009 Jun;54(7):912-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenocarcinoma / pathology. Adipose Tissue / pathology. Prostate / pathology. Prostatic Neoplasms / pathology
  • [MeSH-minor] Aged. Biopsy, Needle. Humans. Male. Neoplasm Invasiveness / pathology. Neoplasm Staging

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  • (PMID = 19469911.001).
  • [ISSN] 1365-2559
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Case Reports; Letter; Review
  • [Publication-country] England
  • [Number-of-references] 5
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59. Agemy L, Harmelin A, Waks T, Leibovitch I, Rabin T, Pfeffer MR, Eshhar Z: Irradiation enhances the metastatic potential of prostatic small cell carcinoma xenografts. Prostate; 2008 Apr 1;68(5):530-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Irradiation is one of the mainstay options for SCCP local treatment, yet, little is known about the clinical response of these aggressive tumors to radiotherapy.
  • RESULTS: Fractionated irradiation of WISH-PC2 xenografts using total doses of >24 Gy induced a delay in tumor growth, while total doses of >36 Gy led to local tumor eradication.
  • Similarly, in the WM-4A xenograft, a total dose of 20 Gy led to tumor growth delay and some of the mice also developed metastases.
  • Non-irradiated local xenografts failed to disseminate, even following surgical excision of the main tumor mass; however, tumor cells administered intravenously did form metastases.
  • Metastases of both xenografts were located in the adrenal/kidney and inter-scapular regions, areas rich in brown adipose tissue.
  • CONCLUSIONS: Clinically, this study raises the possibility that radiation to SCCP may promote metastatic disease.
  • [MeSH-major] Carcinoma, Small Cell / pathology. Carcinoma, Small Cell / radiotherapy. Cell Proliferation / radiation effects. Prostatic Neoplasms / pathology. Prostatic Neoplasms / radiotherapy. Xenograft Model Antitumor Assays
  • [MeSH-minor] Adrenal Gland Neoplasms / secondary. Animals. Disease Models, Animal. Humans. Kidney Neoplasms / secondary. Male. Matrix Metalloproteinase 2 / metabolism. Matrix Metalloproteinase 9 / metabolism. Mice. Mice, SCID. Neoplasm Metastasis / radiotherapy

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  • (PMID = 18247403.001).
  • [ISSN] 0270-4137
  • [Journal-full-title] The Prostate
  • [ISO-abbreviation] Prostate
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] EC 3.4.24.24 / Matrix Metalloproteinase 2; EC 3.4.24.35 / Matrix Metalloproteinase 9
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60. Prantl L, Muehlberg F, Navone NM, Song YH, Vykoukal J, Logothetis CJ, Alt EU: Adipose tissue-derived stem cells promote prostate tumor growth. Prostate; 2010 Nov 1;70(15):1709-15
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  • [Title] Adipose tissue-derived stem cells promote prostate tumor growth.
  • BACKGROUND: Recent evidence indicates that cancer stem cells play an important role in tumor initiation and maintenance.
  • Additionally, the effect of tissue-resident stem cells located in the surrounding healthy tissue on tumor progression has been demonstrated.
  • While most knowledge has been derived from studies of breast cancer cells, little is known regarding the influence of tissue resident stem cells on the tumor biology of prostate cancer.
  • (1) subcutaneous injection of 10(6) MDA PCa 118b human prostate cancer cells into the upper back or (2) subcutaneous injection of 10(6) MDA PCa 118b cells mixed directly with 10(5) GFP-labeled human adipose tissue-derived stem cells (hASCs).
  • Tumor growth and volumes over the ensuing 3 weeks were assessed using calipers and micro-computed tomography.
  • Immunohistochemistry was performed to identify engrafted hASCs in tumor sections.
  • RESULTS: At 3 weeks after injection, the mean tumor volume in the MDA PCa 118b/hASC co-injection group (1019.95 ± 73.49 mm(3)) was significantly higher than that in the MDA PCa 118b-only group (308.70 ± 21.06 mm(3)).
  • Engrafted hASCs exhibited the nuclear marker of proliferation Ki67 and expressed markers for endothelial differentiation, indicating their engraftment in tumor vessels.
  • CONCLUSION: Our study revealed for the first time that ASCs subcutaneously co-injected with prostate cancer cells engraft and promote tumor progression.
  • Further evaluation of the cross-talk between tumor and local tissue-resident stem cells may lead to new strategies for prostate cancer therapy.
  • [MeSH-major] Adipose Tissue / cytology. Neoplastic Stem Cells / pathology. Prostatic Neoplasms / pathology
  • [MeSH-minor] Animals. Disease Models, Animal. Flow Cytometry. Immunophenotyping. Male. Mice. Mice, Nude. Neoplasm Transplantation / methods. Random Allocation. Tomography, X-Ray Computed

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  • (PMID = 20564322.001).
  • [ISSN] 1097-0045
  • [Journal-full-title] The Prostate
  • [ISO-abbreviation] Prostate
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA016672
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS612155; NLM/ PMC4977846
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61. Thompson RH, Leibovich BC, Cheville JC, Webster WS, Lohse CM, Kwon ED, Frank I, Zincke H, Blute ML: Is renal sinus fat invasion the same as perinephric fat invasion for pT3a renal cell carcinoma? J Urol; 2005 Oct;174(4 Pt 1):1218-21
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  • CONCLUSIONS: Our results indicate that clear cell tumors invading the renal sinus fat are more aggressive than tumors with perinephric fat involvement.
  • [MeSH-major] Carcinoma, Renal Cell / pathology. Kidney Neoplasms / pathology
  • [MeSH-minor] Adipose Tissue / pathology. Adrenal Glands / pathology. Aged. Female. Humans. Lymphatic Metastasis. Male. Middle Aged. Multivariate Analysis. Neoplasm Invasiveness. Neoplasm Staging. Prognosis

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  • [CommentIn] Adv Anat Pathol. 2007 Mar;14(2):63-8 [17471114.001]
  • (PMID = 16145373.001).
  • [ISSN] 0022-5347
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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62. Argilés JM, Fontes-Oliveira CC, Fuster G, Ametller E, Figueras M, Olivan M, Lopez-Soriano FJ, Qu X, Demuth J, Stevens P, Varbanov A, Wang F, Isfort RJ, Busquets S: Patterns of gene expression in muscle and fat in tumor-bearing rats: effects of CRF2R agonist on cachexia. Muscle Nerve; 2010 Dec;42(6):936-49
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  • [Title] Patterns of gene expression in muscle and fat in tumor-bearing rats: effects of CRF2R agonist on cachexia.
  • The hypothesis we tested was that administering corticotropin-releasing factor receptor agonists preserves muscle mass during cancer that is related to changes in tissue gene expression. cDNA microarrays were used to compare mRNAs from muscle and adipose tissues of non-treated and agonist-treated tumor-bearing rats.
  • In muscle of non-tumor-bearing agonist-treated animals we observed decreased expression of genes associated with fatty acid uptake and esterification.
  • In tumor-bearing animals, CRF2R agonist administration produced decreased mRNA content of the atrogene lipin-1.
  • In white adipose tissue, agonist treatment of non-tumor-bearing animals induced genes typically related to muscle structure and function.
  • In addition, agonist treatment changed the gene pattern of adipose tissue to render it similar to that of skeletal muscle; thus, treatment with this agonist alters the gene pattern to what could be called "muscularization of white adipose tissue. "
  • [MeSH-major] Adipose Tissue / metabolism. Cachexia / metabolism. Corticotropin-Releasing Hormone / pharmacology. Muscle, Skeletal / metabolism. Receptors, Corticotropin-Releasing Hormone / agonists
  • [MeSH-minor] Analysis of Variance. Animals. Gene Expression. Male. Neoplasm Transplantation. Nuclear Proteins / genetics. Nuclear Proteins / metabolism. RNA, Messenger / genetics. RNA, Messenger / metabolism. Rats. Rats, Wistar. Reverse Transcriptase Polymerase Chain Reaction. Tissue Array Analysis

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  • (PMID = 21104868.001).
  • [ISSN] 1097-4598
  • [Journal-full-title] Muscle & nerve
  • [ISO-abbreviation] Muscle Nerve
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CRF receptor type 2; 0 / Nuclear Proteins; 0 / RNA, Messenger; 0 / Receptors, Corticotropin-Releasing Hormone; 0 / lipin-1 protein, rat; 9015-71-8 / Corticotropin-Releasing Hormone
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63. Dalla Valle R, Mancini C, Crafa P, Passalacqua R: Pancreatic carcinoma recurrence in the remnant pancreas after a pancreaticoduodenectomy. JOP; 2006;7(5):473-7
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  • CONTEXT: We report a rare case of a repeated pancreatic resection in the remnant distal pancreas 18 months after a Whipple R0 procedure.
  • In September 2004, the tumor marker level increased and MR revealed a tumor in the remnant pancreas.
  • There were no findings of invasion into the surrounding tissue or distant metastasis.
  • Histopathologically, the tumor was classified as a ductal adenocarcinoma like the tumor which had been removed during the first operation, with infiltration of peripancreatic adipose tissue and a segmentary tract of the transverse mesocolon, without lymph node metastasis.
  • Otherwise the high rate of multicentricity in pancreatic cancer may also explain the development of a secondary cancer in the remnant pancreas, even though the interval was relatively brief.
  • [MeSH-major] Carcinoma, Pancreatic Ductal / pathology. Carcinoma, Pancreatic Ductal / surgery. Neoplasm Recurrence, Local / pathology. Pancreatic Neoplasms / pathology. Pancreatic Neoplasms / surgery. Pancreaticoduodenectomy

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  • (PMID = 16998244.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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64. Kim JI, Choi KU, Lee IS, Moon TY, Lee CH, Kim HW, Kim JY, Park DY, Sol MY: Gene expression in mixed type liposarcoma. Pathology; 2006 Apr;38(2):114-9
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  • Here, we analysed the characteristics of an unusual case of mixed type liposarcoma, which consisted of a well-differentiated liposarcoma (WDL) and a pleomorphic liposarcoma (PL), with a special emphasis on molecular alterations.
  • METHODS: Microscopic and immunohistochemical approaches were used to investigate this case of mixed type liposarcoma, and to identify molecular alterations in this tumour, gene expression was examined in PL, WDL, and normal adipose tissue (NA) samples using a 17,000 cDNA microarray.
  • RESULTS: The tumour mass, 9 x 5 x 5 cm, was located in the left upper arm of a 76-year-old man.
  • Grossly, the proximal portion of the tumour was composed of a yellowish fatty lesion, whereas the distal portion of the tumour was whitish and necrotic in nature.
  • Histologically, the tumour was composed of two distinct components.
  • The proximal component of the tumour was a WDL and the distal component was a PL.
  • Immunohistochemically, S100 protein immunoreactivity highlighted lipoblasts in both tumour portions.
  • [MeSH-major] Gene Expression Regulation, Neoplastic. Liposarcoma / genetics. Soft Tissue Neoplasms / genetics
  • [MeSH-minor] Adipose Tissue / anatomy & histology. Adipose Tissue / chemistry. Aged. Biomarkers, Tumor / analysis. DNA, Neoplasm / analysis. Gene Expression Profiling. Humans. Immunohistochemistry. Male. Oligonucleotide Array Sequence Analysis

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  • [CommentIn] Pathology. 2006 Apr;38(2):101-2 [16581648.001]
  • (PMID = 16581650.001).
  • [ISSN] 0031-3025
  • [Journal-full-title] Pathology
  • [ISO-abbreviation] Pathology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Neoplasm
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65. Hong SM, Presley AE, Stelow EB, Frierson HF Jr, Moskaluk CA: Reconsideration of the histologic definitions used in the pathologic staging of extrahepatic bile duct carcinoma. Am J Surg Pathol; 2006 Jun;30(6):744-9
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  • The histologic boundaries of the extrahepatic bile ducts (EBDs) are not well defined, despite the fact that pathologic staging of carcinomas arising in these structures requires the determination of extent of tumor invasion in this area.
  • Perhaps in part, because the smooth muscle band in the EBD wall is not well formed throughout the length of these structures, a previous definition of the outer portion of the bile duct wall included "loose, richly vascularized connective tissue, interlaced with large nerve fibers."
  • To systematically study the histologic features of EBD tissue boundaries, 34 EBD specimens obtained from autopsy were analyzed with attention to the distribution of blood vessels and nerve fibers along the length of this system.
  • Blood vessels and nerve fibers are located predominantly outside of the fibromuscular wall and are usually surrounded by adipose tissue throughout the entire EBD, however, their distribution in this location is not consistent.
  • Because of these histologic features, we propose that the bile duct wall is more precisely defined as occurring between the mucosa and the outermost boundary of dense fibromuscular tissue, without consideration of the presence or absence of blood vessels and nerve fibers.
  • [MeSH-major] Bile Duct Neoplasms / pathology. Bile Ducts, Extrahepatic / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Neoplasm Staging

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  • (PMID = 16723853.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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66. Li H, Fan X, Kovi RC, Jo Y, Moquin B, Konz R, Stoicov C, Kurt-Jones E, Grossman SR, Lyle S, Rogers AB, Montrose M, Houghton J: Spontaneous expression of embryonic factors and p53 point mutations in aged mesenchymal stem cells: a model of age-related tumorigenesis in mice. Cancer Res; 2007 Nov 15;67(22):10889-98
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  • Based on the facts that mesenchymal stem cells (MSC) transform with higher frequency than other cell types, and tumors in aged C57BL/6 mice are frequently fibrosarcomas, we used a genetically tagged bone marrow (BM) transplant model to show that aged mice develop MSC-derived fibrosarcomas.
  • Spontaneously transformed MSCs contribute directly to the tumor, tumor vasculature, and tumor adipose tissue, recruit additional host BM-derived cells (BMDC) to the area, and fuse with the host BMDC.
  • Unfused transformed MSCs act as the cancer stem cell and are able to form tumors in successive mice, whereas fusion restores a nonmalignant phenotype.
  • These data suggest that MSCs may play a key role in age-related tumors, and fusion with host cells restores a nonmalignant phenotype, thereby providing a mechanism for regulating tumor cell activity.


67. Weaver J, Rao P, Goldblum JR, Joyce MJ, Turner SL, Lazar AJ, López-Terada D, Tubbs RR, Rubin BP: Can MDM2 analytical tests performed on core needle biopsy be relied upon to diagnose well-differentiated liposarcoma? Mod Pathol; 2010 Oct;23(10):1301-6
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  • Well-differentiated liposarcoma/atypical lipomatous tumor can be difficult to differentiate from benign lipomatous tumors, especially on limited biopsy material.
  • Adjunctive tests for MDM2 (murine double minute 2) have proven useful in whole-tissue sections; however, their utility has not been determined within the increasingly popular core needle biopsy.
  • Herein, we compare the ability of MDM2 immunohistochemistry and MDM2 fluorescence in situ hybridization (FISH) to discriminate benign lipomatous tumors from well-differentiated liposarcoma on core needle biopsies.
  • Well-differentiated liposarcoma (n=17) and an assortment of benign lipomatous tumors (n=37), which had concurrent or previous core needle biopsies, and resection specimens were subjected to both MDM2 immunohistochemistry and MDM2 FISH on both whole-tissue sections and corresponding core needle biopsy sections.
  • Percentage tumor cells positive for MDM2 by immunohistochemistry and an MDM2:CEP12 FISH ratio was calculated in each biopsy and resection specimen pair and the results were compared.
  • The average MDM2:CEP12 ratio was similar in the biopsy material compared with the whole-tissue sections in both well-differentiated liposarcoma and the benign lipomatous tumor group of neoplasms.
  • Detection of MDM2 amplification by FISH is a more sensitive and specific adjunctive test than MDM2 immunohistochemistry to differentiate well-differentiated liposarcoma from various benign lipomatous tumors, especially on limited tissue samples.
  • [MeSH-major] Biomarkers, Tumor / analysis. Biopsy, Needle. Liposarcoma / diagnosis. Proto-Oncogene Proteins c-mdm2 / biosynthesis
  • [MeSH-minor] Diagnosis, Differential. Humans. Immunohistochemistry. In Situ Hybridization, Fluorescence. Lipoma / diagnosis. Sensitivity and Specificity


68. Savoldelli C, Righini C, Reyt E, Lebeau J, Bettega G: [Lateral transmandibular route for deep-lobe parotid tumor excision]. Rev Stomatol Chir Maxillofac; 2009 Jun;110(3):150-4
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  • [Title] [Lateral transmandibular route for deep-lobe parotid tumor excision].
  • [Transliterated title] Abord transmandibulaire latéral pour l'exérèse des tumeurs du lobe profond de la parotide.
  • The parapharyngeal space may be a site for tumors, especially for those developed in the deep parotid lobe.
  • The surgical route to parapharyngeal space tumors is a challenge because of neighbor anatomic structures and the specific risk of mandibular nerve damage.
  • [MeSH-major] Mandible / surgery. Parotid Neoplasms / surgery
  • [MeSH-minor] Adenoma, Pleomorphic / surgery. Adipose Tissue / pathology. Bone Plates. Connective Tissue / pathology. Fascia / pathology. Humans. Intraoperative Complications / prevention & control. Mandibular Condyle / surgery. Mandibular Nerve / pathology. Masseter Muscle / surgery. Neck Muscles / pathology. Neck Muscles / surgery. Neoplasm Invasiveness. Pharyngeal Muscles / pathology. Pharynx / surgery. Pterygoid Muscles / pathology. Reconstructive Surgical Procedures / instrumentation. Reconstructive Surgical Procedures / methods. Temporal Muscle / surgery. Trigeminal Nerve Injuries

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  • (PMID = 19423144.001).
  • [ISSN] 1776-257X
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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69. Cymet-Ramírez J, Martínez-Flores LM, Villalobos Garduño FE: [Lipoblastoma. A case report]. Acta Ortop Mex; 2007 May-Jun;21(3):151-3
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  • [Transliterated title] Lipoblastoma. Reporte de un caso.
  • Lipoblastoma is an rare benign tumors of infancy of fetal adipose tissue, that usually affect infants and children less than 3 years of age.
  • The tumor was completely excised surgically.
  • The clinical diagnosis of lipoblastoma was confirmed pathologically.
  • This experience is illustrative for the orthopaedic surgeon, because it shows the importance to performe a complete clinical examination in all patients, to avoid the omission in the diagnosis of this pathology.
  • [MeSH-major] Knee. Lipoma / diagnosis. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Child, Preschool. Humans. Incidental Findings. Magnetic Resonance Imaging. Male. Muscle, Skeletal / pathology. Neoplasm Invasiveness

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  • (PMID = 17937179.001).
  • [ISSN] 2306-4102
  • [Journal-full-title] Acta ortopédica mexicana
  • [ISO-abbreviation] Acta Ortop Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
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70. Hekal IA: Editorial comment to Anterior perirectal fat tissue thickness closely associated with obesity strongly predicts recurrence after high-intensity focused ultrasound for prostate cancer. Int J Urol; 2010 Sep;17(9):782-3
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  • [Title] Editorial comment to Anterior perirectal fat tissue thickness closely associated with obesity strongly predicts recurrence after high-intensity focused ultrasound for prostate cancer.
  • [MeSH-major] Adipose Tissue / pathology. Neoplasm Recurrence, Local / epidemiology. Obesity / complications. Prostatic Neoplasms / epidemiology. Prostatic Neoplasms / surgery. Ultrasound, High-Intensity Focused, Transrectal

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  • [CommentOn] Int J Urol. 2010 Sep;17(9):776-82 [20569272.001]
  • (PMID = 20727049.001).
  • [ISSN] 1442-2042
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Comment; Editorial
  • [Publication-country] Australia
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71. Colas S, Germain E, Arab K, Maheo K, Goupille C, Bougnoux P: Alpha-tocopherol suppresses mammary tumor sensitivity to anthracyclines in fish oil-fed rats. Nutr Cancer; 2005;51(2):178-83
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  • [Title] Alpha-tocopherol suppresses mammary tumor sensitivity to anthracyclines in fish oil-fed rats.
  • Polyunsaturated fatty acids (PUFAs) have been reported to enhance the efficacy of chemotherapeutic agents that produce reactive oxygen species such as anthracyclines.
  • To determine the relevance of this observation in vivo, we examined the effect of the oxidative status of the diet on the activity of epirubicin against N-methylnitrosourea-induced mammary tumors in Sprague-Dawley rats.
  • When the first mammary tumor reached 1 cm2, epirubicin was administrated weekly for 3 wk, and subsequent change in tumor size was documented over time.
  • Two weeks after the end of epirubicin injections, tumor size was increased by 34% in the control group.
  • In the pro-oxidant group, tumor size was decreased by 50%.
  • In contrast, tumor size was increased by 188% in the antioxidant group.
  • Thus, addition of pro-oxidants in a fish oil-enriched diet increased the sensitization of mammary tumors to chemotherapy, whereas addition of alpha-tocopherol suppressed tumor response in vivo, indicating that interaction between components of the diet has to be carefully controlled during chemotherapy.
  • [MeSH-major] Anthracyclines / antagonists & inhibitors. Anthracyclines / pharmacology. Antioxidants / pharmacology. Diet / adverse effects. Drug Resistance, Neoplasm / drug effects. Fish Oils / administration & dosage. Mammary Neoplasms, Experimental / drug therapy. alpha-Tocopherol / pharmacology
  • [MeSH-minor] Adipose Tissue / drug effects. Adipose Tissue / metabolism. Animals. Antibiotics, Antineoplastic / antagonists & inhibitors. Antibiotics, Antineoplastic / pharmacology. Carcinogens. Disease Models, Animal. Drug Antagonism. Epirubicin / antagonists & inhibitors. Epirubicin / pharmacology. Fatty Acids, Unsaturated / pharmacology. Female. Malondialdehyde / metabolism. Methylnitrosourea. Oxidants / administration & dosage. Rats. Rats, Sprague-Dawley. Time Factors

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  • (PMID = 15860440.001).
  • [ISSN] 0163-5581
  • [Journal-full-title] Nutrition and cancer
  • [ISO-abbreviation] Nutr Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anthracyclines; 0 / Antibiotics, Antineoplastic; 0 / Antioxidants; 0 / Carcinogens; 0 / Fatty Acids, Unsaturated; 0 / Fish Oils; 0 / Oxidants; 3Z8479ZZ5X / Epirubicin; 4Y8F71G49Q / Malondialdehyde; 684-93-5 / Methylnitrosourea; H4N855PNZ1 / alpha-Tocopherol
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72. Jung SJ, Ro JY, Truong LD, Ayala AG, Shen SS: Reappraisal of T3N0/NxM0 renal cell carcinoma: significance of extent of fat invasion, renal vein invasion, and adrenal invasion. Hum Pathol; 2008 Nov;39(11):1689-94
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  • T3 renal cell carcinoma (RCC) is a heterogeneous group of tumors that are substaged based on perirenal or sinus fat invasion, adrenal invasion, and renal vein invasion.
  • Multivariate analysis showed that nuclear grade, sarcomatoid differentiation, and subgrouping of pT3 RCC (fat invasion, renal vein invasion, and adrenal invasion) remained independent predictors of patient's overall survival.
  • In contrast, tumors with adrenal gland invasion carry a far worse prognosis than perinephric fat or renal vein invasion and thus supporting a separate stage category.
  • [MeSH-major] Adipose Tissue / pathology. Adrenal Glands / pathology. Carcinoma, Renal Cell / pathology. Kidney Neoplasms / pathology. Neoplasm Invasiveness / pathology. Renal Veins / pathology
  • [MeSH-minor] Adrenal Gland Neoplasms / mortality. Adrenal Gland Neoplasms / pathology. Adrenal Gland Neoplasms / secondary. Adult. Aged. Aged, 80 and over. Female. Humans. Kaplan-Meier Estimate. Kidney / pathology. Male. Middle Aged. Neoplasm Staging. Regression Analysis. Retrospective Studies

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  • (PMID = 18656240.001).
  • [ISSN] 1532-8392
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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73. Kijima Y, Yoshinaka H, Owaki T, Aikou T: Early experience of immediate reconstruction using autologous free dermal fat graft after breast conservational surgery. J Plast Reconstr Aesthet Surg; 2007;60(5):495-502
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  • The mean amount of resected tissue was 56.4 g (range, 28-108 g), while mean FDFG weight was 78.3g (range, 35-148 g).
  • This technique achieves better cosmetic results than the transposition of residual breast tissue, is more convenient than muscle flap grafting, and safer than implantation of foreign materials.
  • [MeSH-major] Adipose Tissue / transplantation. Breast Neoplasms / surgery. Carcinoma, Ductal, Breast / surgery. Mammaplasty / methods
  • [MeSH-minor] Adult. Aged. Breast / pathology. Breast / surgery. Female. Humans. Mastectomy, Segmental. Middle Aged. Neoplasm Invasiveness. Skin Transplantation / methods. Time Factors. Treatment Outcome

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  • (PMID = 17399658.001).
  • [ISSN] 1748-6815
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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74. Kuriu A, Shimono T, Kuwabara M, Ashikaga R, Hosono M, Murakami T: Fourth ventricular mixed germ cell tumor demonstrating adipose tissue in a young adult. Jpn J Radiol; 2010 Feb;28(2):166-8
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  • [Title] Fourth ventricular mixed germ cell tumor demonstrating adipose tissue in a young adult.
  • We report a case of fourth ventricular mixed germ cell tumor (GCT) in a 20-year-old man.
  • Neuroradiological investigations revealed a fourth ventricular hemorrhagic tumor with adipose tissue.
  • We suspected mixed GCT because adipose tissue was seen preoperatively, but mixed GCT occurring after childhood in this location has not previously been reported.
  • We describe herein the imaging findings for mixed GCT and discuss the differential diagnoses of fourth ventricular tumors with adipose tissue.
  • [MeSH-major] Adipose Tissue / diagnostic imaging. Adipose Tissue / pathology. Brain Neoplasms / diagnosis. Fourth Ventricle / diagnostic imaging. Fourth Ventricle / pathology. Neoplasms, Germ Cell and Embryonal / diagnosis
  • [MeSH-minor] Adult. Biomarkers / blood. Biomarkers, Tumor / blood. Cerebral Ventriculography / methods. Chorionic Gonadotropin / blood. Contrast Media. Diagnosis, Differential. Follow-Up Studies. Headache / etiology. Humans. Hydrocephalus / complications. Image Enhancement / methods. Magnetic Resonance Imaging / methods. Male. Tomography, X-Ray Computed / methods. Vomiting / etiology. Young Adult. alpha-Fetoproteins

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  • [Cites] Clin Neurol Neurosurg. 2009 Sep;111(7):636-7 [19540038.001]
  • [Cites] J Clin Neurosci. 2009 Feb;16(2):321-5 [19091568.001]
  • [Cites] No Shinkei Geka. 1980 Dec;8(12 ):1177-82 [6165917.001]
  • [Cites] Neurosurgery. 1987 Sep;21(3):404-10 [3313095.001]
  • [Cites] J Neurooncol. 1994;19(3):217-26 [7807172.001]
  • [Cites] Am J Surg Pathol. 1996 Apr;20(4):413-8 [8604807.001]
  • [Cites] Neuropathology. 2009 Apr;29(2):176-80 [18627482.001]
  • [Cites] J Neurooncol. 2005 Jan;71(1):53-9 [15719276.001]
  • [Cites] Acta Neurochir (Wien). 2003 Sep;145(9):789-92; discussion 792 [14505107.001]
  • [Cites] Brain Dev. 1994 Sep-Oct;16(5):396-8 [7892960.001]
  • [Cites] Pathol Oncol Res. 2000;6(2):136-40 [10936790.001]
  • (PMID = 20182853.001).
  • [ISSN] 1867-108X
  • [Journal-full-title] Japanese journal of radiology
  • [ISO-abbreviation] Jpn J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Biomarkers, Tumor; 0 / Chorionic Gonadotropin; 0 / Contrast Media; 0 / alpha-Fetoproteins
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75. de Wijn RS, van der Heijden EP, Kon M: On lipoma of the buccal fat pad: report of two cases and review of the literature. J Plast Reconstr Aesthet Surg; 2009 Jan;62(1):28-35
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  • As the deep extensions are not routinely removed due to the difficulty of the procedure, this could result in incomplete resection and recurrence.
  • [MeSH-major] Facial Neoplasms / diagnosis. Lipoma / diagnosis. Neoplasms, Adipose Tissue / diagnosis
  • [MeSH-minor] Adult. Cheek. Female. Humans. Infant. Magnetic Resonance Imaging. Middle Aged. Neoplasm Recurrence, Local / pathology

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  • (PMID = 18249050.001).
  • [ISSN] 1878-0539
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 63
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76. He M, Aisner S, Benevenia J, Patterson F, Aviv H, Hameed M: p16 immunohistochemistry as an alternative marker to distinguish atypical lipomatous tumor from deep-seated lipoma. Appl Immunohistochem Mol Morphol; 2009 Jan;17(1):51-6
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  • [Title] p16 immunohistochemistry as an alternative marker to distinguish atypical lipomatous tumor from deep-seated lipoma.
  • Atypical lipomatous tumor (ALT)/well-differentiated liposarcoma (WDLPS) is a locally aggressive malignant mesenchymal neoplasm, resembling ordinary lipoma in many clinical aspects.
  • Fifty cases of lipomatous neoplasms, with cytogenetic results, from 45 patients were collected from the archives in Department of Pathology, University of Medicine and Dentistry of New Jersey/New Jersey Medical School during 1998 to 2006.

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  • (PMID = 18779733.001).
  • [ISSN] 1533-4058
  • [Journal-full-title] Applied immunohistochemistry & molecular morphology : AIMM
  • [ISO-abbreviation] Appl. Immunohistochem. Mol. Morphol.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / Neoplasm Proteins; EC 6.3.2.19 / MDM2 protein, human; EC 6.3.2.19 / Proto-Oncogene Proteins c-mdm2
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77. Cho HJ, Kim SJ, Ha US, Hong SH, Kim JC, Choi YJ, Hwang TK: Prognostic value of capsular invasion for localized clear-cell renal cell carcinoma. Eur Urol; 2009 Dec;56(6):1006-12
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  • We analyzed clinical (presentation and body mass index [BMI]) and pathologic (tumor size, Fuhrman nuclear grade, collecting system invasion, microvascular invasion, and capsular involvement) parameters.
  • Capsular invasion had a statistically significant association with age, symptomatic presentation, tumor diameter, pathologic stage, collecting system invasion, and microvascular invasion.
  • The 5-yr RFS and CSS rates for tumors with capsular invasion were significantly lower compared with rates for tumors without invasion (77.7% vs 92.3% and 85.5% vs 95.7%, respectively; p=0.0004).
  • Multivariate analysis showed that BMI (hazard ratio [HR]=0.19), stage (HR=2.45), and capsular invasion (HR=3.36) were independent prognostic factors of disease recurrence.
  • With respect to CSS, BMI (HR=0.20), tumor size (HR=1.13), and capsular invasion (HR=4.03) were the factors related to death.
  • [MeSH-major] Adipose Tissue / pathology. Carcinoma, Renal Cell / mortality. Carcinoma, Renal Cell / pathology. Kidney Neoplasms / mortality. Kidney Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Fascia / pathology. Female. Humans. Kaplan-Meier Estimate. Male. Middle Aged. Multivariate Analysis. Neoplasm Invasiveness / pathology. Neoplasm Recurrence, Local / mortality. Neoplasm Staging / mortality. Predictive Value of Tests. Prognosis. Proportional Hazards Models


78. Choi SW, Song SH: Intrapelvic lipoblastoma with massive spinal canal invasion. Childs Nerv Syst; 2007 May;23(5):581-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTS: The lipoblastoma is a rare benign pediatric neoplasm that derives from embryonic white fat cells.
  • However, this tumor with spinal invasion in children is extremely rare.
  • We report a case of a 3-year-old boy who had lipoblastoma with massive invasion into the lower lumbosacral spinal canal.
  • Histopathologic diagnosis confirmed the lipoblastoma.
  • CONCLUSION: Lipoblastoma is a rare benign neoplasm and lumbosacral invasion is unique.
  • [MeSH-major] Lipoma / pathology. Neoplasms, Adipose Tissue / pathology. Pelvic Neoplasms / pathology. Spinal Cord Neoplasms / secondary

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  • [Cites] Pediatr Surg Int. 2000;16(5-6):458-61 [10955594.001]
  • [Cites] Am J Surg Pathol. 1997 Oct;21(10):1131-7 [9331284.001]
  • [Cites] Pediatrics. 2000 Jan;105(1 Pt 1):123-8 [10617716.001]
  • [Cites] Am J Pathol. 1958 Nov-Dec;34(6):1149-59 [13583102.001]
  • [Cites] J Pediatr Surg. 2001 Jan;36(1):229-31 [11150471.001]
  • [Cites] J Pediatr Surg. 1982 Jun;17(3):277-80 [7108715.001]
  • [Cites] Cancer. 1973 Aug;32(2):482-92 [4353020.001]
  • [Cites] Histopathology. 1993 Dec;23(6):527-33 [8314236.001]
  • [Cites] Clin Imaging. 2002 Jan-Feb;26(1):23-6 [11814748.001]
  • [Cites] Pediatr Radiol. 2003 Jan;33(1):37-40 [12497236.001]
  • [Cites] J Pediatr Surg. 2001 Jun;36(6):905-7 [11381423.001]
  • (PMID = 17143644.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Coloring Agents
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79. Ogütcen-Toller M, Sener I, Kasap V, Cakir-Ozkan N: Maxillary myxoma: surgical treatment and reconstruction with buccal fat pad flap: a case report. J Contemp Dent Pract; 2006 Feb 15;7(1):107-16
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  • Myxoma is a benign tumor that arises from mesenchymal tissue and is found less commonly in the bone than in soft tissue.
  • When compared with other odontogenic tumors, myxoma of the jaws is a rare entity.
  • Numerous types of treatment have been used for these tumors including simple curettage, enucleation, curettage with peripheral ostectomy, and en bloc resection with or without immediate reconstruction.
  • The buccal fat pad (BFP) is a lobulated mass of fatty tissue in the oromaxillofacial region, which has long been a source of grafts in facial augmentation.
  • A case of an odontogenic myxoma in the left maxillary molar area of a 34-year-old female that was treated by curettage and peripheral ostectomy is presented.
  • [MeSH-major] Adipose Tissue / transplantation. Maxillary Neoplasms / surgery. Myxoma / surgery. Oral Surgical Procedures / methods
  • [MeSH-minor] Adult. Bone Substitutes. Bone Transplantation. Cheek. Female. Follow-Up Studies. Humans. Neoplasm Invasiveness. Oroantral Fistula / surgery. Reconstructive Surgical Procedures. Surgical Flaps. Tomography, X-Ray Computed

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  • (PMID = 16491153.001).
  • [ISSN] 1526-3711
  • [Journal-full-title] The journal of contemporary dental practice
  • [ISO-abbreviation] J Contemp Dent Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Bone Substitutes; 0 / OsteoGraf-N
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80. Oosterling SJ, van der Bij GJ, Bögels M, van der Sijp JR, Beelen RH, Meijer S, van Egmond M: Insufficient ability of omental milky spots to prevent peritoneal tumor outgrowth supports omentectomy in minimal residual disease. Cancer Immunol Immunother; 2006 Sep;55(9):1043-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Insufficient ability of omental milky spots to prevent peritoneal tumor outgrowth supports omentectomy in minimal residual disease.
  • BACKGROUND: The greater omentum is frequently involved in the course of gastrointestinal and ovarian tumors.
  • Paradoxically, many immune cells, such as macrophages that accumulate in so-called milky spots, reside within the omentum and are cytotoxic against tumor cells ex vivo.
  • Consequently, omental macrophages might play an important role in killing tumor cells, and may hereby prevent development into local peritoneal recurrences.
  • In the present study, we therefore evaluated the role of the omentum and the clinical relevance of omentectomy in minimal residual disease (MRD).
  • METHODS: Tumor cell dissemination patterns on the omentum in a rat model were examined using DiI-labelled CC531s tumor cells.
  • Additionally, intra peritoneal (i.p.) tumor load was investigated in rats that underwent omentectomy or sham laparotomy followed by i.p. injection of CC531s cells on day 21, which represented MRD.
  • RESULTS: At 4 h post injection, tumor cells predominantly adhered on milky spots.
  • Number of cells thereafter declined rapidly suggesting initial tumor killing functions in these specific immune aggregates.
  • Despite initial reduction observed in milky spots, numbers of tumor cells however increased at fatty tissue stripes that border the omentum.
  • This indicated proliferation at these locations, which corresponded to macroscopic observations of the omenta on day 21 after tumor cell injection.
  • Omentectomy resulted in reduced intra-abdominal tumor load, which was completely attributable to the absence of the omentum, as tumor development did not differ on other sites.
  • Even in the MRD group microscopic clusters of tumor cells located in the omentum eventually developed into macroscopic nodules.
  • CONCLUSION: Since the ability of omental milky spots is, even in MRD, insufficient to prevent intra abdominal tumor outgrowth, omentectomy, which reduces tumor load, is recommended in surgical treatment of intra abdominal tumors that are prone to disseminate intraperitoneally.
  • [MeSH-major] Adenocarcinoma / prevention & control. Colonic Neoplasms / prevention & control. Omentum / pathology. Omentum / surgery. Peritoneal Neoplasms / prevention & control
  • [MeSH-minor] Adipose Tissue / pathology. Animals. Cell Adhesion / immunology. Cell Line, Tumor. Cell Proliferation. Digestive System Surgical Procedures. Disease Models, Animal. Lymphoid Tissue / pathology. Macrophages / immunology. Male. Neoplasm Transplantation. Neoplasm, Residual. Rats

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  • (PMID = 16311732.001).
  • [ISSN] 0340-7004
  • [Journal-full-title] Cancer immunology, immunotherapy : CII
  • [ISO-abbreviation] Cancer Immunol. Immunother.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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81. Trahan S, Erickson-Johnson MR, Rodriguez F, Aubry MC, Cheville JC, Myers JL, Oliveira AM: Formation of the 12q14-q15 amplicon precedes the development of a well-differentiated liposarcoma arising from a nonchondroid pulmonary hamartoma. Am J Surg Pathol; 2006 Oct;30(10):1326-9
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  • [Title] Formation of the 12q14-q15 amplicon precedes the development of a well-differentiated liposarcoma arising from a nonchondroid pulmonary hamartoma.
  • Pulmonary hamartoma is a benign neoplasm that rarely recurs or undergoes malignant transformation.
  • Herein, we report a 48-year-old woman with a history of an incomplete excised nonchondroid pulmonary hamartoma presenting as an indolent tumor recurrence.
  • Excision of the tumor revealed a well-differentiated liposarcoma arising from the hamartomatous component.
  • These findings suggest that the formation of the 12q14-q15 chromosome amplicon, the characteristic cytogenetic finding of well-differentiated liposarcomas and the structural genomic component of the supernumerary ring and giant rod chromosomes, occurred before the morphologic changes characteristic of these malignant adipose tissue tumors and likely represents a very early molecular event in their development.
  • [MeSH-major] Chromosomes, Human, Pair 12. Gene Amplification. Hamartoma / genetics. Liposarcoma / genetics. Lung Neoplasms / genetics

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  • (PMID = 17001166.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Genetic Markers; 0 / HMGA2 Protein; EC 6.3.2.19 / MDM2 protein, human; EC 6.3.2.19 / Proto-Oncogene Proteins c-mdm2
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82. Kurita H, Kamata T, Koike T, Kobayashi H, Kurashina K: Intraoperative tissue staining of invaded oral carcinoma. Pathol Oncol Res; 2008 Dec;14(4):461-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intraoperative tissue staining of invaded oral carcinoma.
  • The purpose of this study was to assess the ability of intraoperative tissue staining with consecutive application of 0.4% indigo carmine and 0.5% Congo red to demonstrate the extent and border of oral carcinoma invasion.
  • Once the oral tumor was resected, a vertical section of surgical specimen was taken from the central part of the tumor.
  • The extent and border of the invaded carcinoma were assessed on digital microscopic examination with tissue staining.
  • Tissue staining produced a brown-black stain on normal muscle, connective, and salivary tissues but not tumor and epithelial tissues.
  • It clearly demonstrated the extent and border of tumor invasion in 13 of 17 patients (76.5%); however, detection of remnant vital tumor cells in scar tissue after neoadjuvant chemotherapy, and distinction between the tumor and adipose tissue scattered in the muscle tissue was difficult.
  • The results of this study showed that intraoperative tissue staining was a possible method in demonstrating the extent and border of carcinoma deeply invaded in the soft tissue and selecting the site for additional frozen section analysis, although the method needed some refinement.
  • [MeSH-major] Carcinoma / pathology. Carcinoma / surgery. Mouth Neoplasms / pathology. Mouth Neoplasms / surgery. Neoplasm Staging / methods. Staining and Labeling / methods

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  • [Cites] Trans Am Acad Ophthalmol Otolaryngol. 1974 Jan-Feb;78(1):ORL49-53 [4813646.001]
  • [Cites] Cancer. 1982 Dec 15;50(12):2956-60 [7139587.001]
  • [Cites] J Oral Maxillofac Surg. 2003 Aug;61(8):890-4; discussion 895-7 [12905439.001]
  • [Cites] Int J Oral Maxillofac Surg. 2003 Apr;32(2):152-8 [12729775.001]
  • [Cites] Can J Gastroenterol. 1999 Jun;13(5):423-9 [10377475.001]
  • [Cites] Baillieres Best Pract Res Clin Gastroenterol. 1999 Apr;13(1):11-9 [11030630.001]
  • [Cites] Am J Surg. 2006 Jan;191(1):84-8 [16399112.001]
  • [Cites] Am J Surg. 1978 Oct;136(4):525-8 [707736.001]
  • (PMID = 18575826.001).
  • [ISSN] 1219-4956
  • [Journal-full-title] Pathology oncology research : POR
  • [ISO-abbreviation] Pathol. Oncol. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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83. Aron M, Aydin H, Sercia L, Magi-Galluzzi C, Zhou M: Renal cell carcinomas with intratumoral fat and concomitant angiomyolipoma: potential pitfalls in staging and diagnosis. Am J Clin Pathol; 2010 Nov;134(5):807-12
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  • [Title] Renal cell carcinomas with intratumoral fat and concomitant angiomyolipoma: potential pitfalls in staging and diagnosis.
  • Intratumoral fat and angiomyolipomas (AMLs) occurring within renal cell carcinomas (RCCs) have rarely been reported but may be mistaken for tumor invasion into perinephric or renal sinus fat or misdiagnosed as tumor exhibiting sarcomatoid differentiation.
  • Intratumoral fat or AML at the periphery of RCC simulated the invasion into the fat, while the smooth muscle component of AML resembled spindle cell, or sarcomatoid, differentiation.
  • Our study highlights the potential pitfalls in staging and diagnosis when intratumoral fat or AML is found within RCC.
  • [MeSH-major] Adipose Tissue / pathology. Angiomyolipoma / pathology. Carcinoma, Renal Cell / pathology. Kidney / pathology. Kidney Neoplasms / pathology. Neoplasms, Multiple Primary / pathology
  • [MeSH-minor] Adult. Aged. Calcinosis / pathology. Female. Humans. Male. Middle Aged. Neoplasm Staging

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  • (PMID = 20959665.001).
  • [ISSN] 1943-7722
  • [Journal-full-title] American journal of clinical pathology
  • [ISO-abbreviation] Am. J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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84. Yoo C, Song C, Hong JH, Kim CS, Ahn H: Prognostic significance of perinephric fat infiltration and tumor size in renal cell carcinoma. J Urol; 2008 Aug;180(2):486-91; discussion 491
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  • [Title] Prognostic significance of perinephric fat infiltration and tumor size in renal cell carcinoma.
  • Therefore, we evaluated the influence of perinephric fat infiltration and tumor size on patient survival.
  • Univariate and multivariate analyses of prognostic factors, including perinephric fat infiltration, on cancer specific and disease-free survival were performed.
  • RESULTS: Patients with pT1-2 and pT3a tumors had a 5-year cancer specific survival rate of 96.1% and 84.9%, and a 5-year disease-free survival rate of 93.4% and 74.7%, respectively (each p <0.01).
  • Age, tumor size and Fuhrman nuclear grade were independent prognostic factors for cancer specific and disease-free survival, whereas perinephric fat infiltration was significant only for disease-free survival.
  • However, perinephric fat infiltration had a significant effect on cancer specific survival in patients with pT3a tumors more than 7 cm (p = 0.001).
  • In contrast, patients with pT3a tumors 7 cm or less had cancer specific and disease-free survival similar to that of patients with pT2 tumors.
  • Recurrence of pT3a tumors greater than 7 cm was observed in 44% of patients but in only 14.6% of those with pT3a tumors 7 cm or less (p = 0.029).
  • In contrast to the recurrence of tumors 7 cm or less, recurrence of pT3a tumors more than 7 cm usually developed at multiple sites with a large tumor burden and it progressed rapidly.
  • Consequently 85% of patients with recurrence of pT3a tumors larger than 7 cm died of renal cell carcinoma compared with 33% of those with recurrence of pT3a tumors 7 cm or less (p = 0.001).
  • CONCLUSIONS: In pT3a renal cell carcinoma tumor size was the strongest prognostic factor of disease-free and cancer specific survival.
  • Perinephric fat infiltration was an independent prognostic factor for disease-free survival but not for cancer specific survival due to the less aggressive behavior of small (7 cm or less) pT3a tumors after recurrence.
  • Tumor size and perinephric fat infiltration should be included in T3a renal cell carcinoma staging.
  • [MeSH-major] Adipose Tissue / pathology. Carcinoma, Renal Cell / mortality. Carcinoma, Renal Cell / pathology. Kidney Neoplasms / mortality. Kidney Neoplasms / pathology. Tumor Burden
  • [MeSH-minor] Adult. Aged. Biopsy, Needle. Cause of Death. Cohort Studies. Female. Humans. Immunohistochemistry. Male. Middle Aged. Multivariate Analysis. Neoplasm Staging. Nephrectomy / methods. Predictive Value of Tests. Prognosis. Proportional Hazards Models. Reference Values. Retrospective Studies. Risk Assessment. Survival Analysis. Treatment Outcome

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  • (PMID = 18550101.001).
  • [ISSN] 1527-3792
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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85. Ilie M, Hofman V, Pedeutour F, Attias R, Santini J, Hofman P: Oncocytic lipoadenoma of the parotid gland: Immunohistochemical and cytogenetic analysis. Pathol Res Pract; 2010 Jan 15;206(1):66-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Salivary gland oncocytic lipoadenoma is an exceptional benign tumor composed of mature adipose tissue associated with a mixture of oncocytes.
  • We report a case of oncocytic lipoadenoma showing sebaceous differentiation, and provide a cytogenetic analysis, which has not yet been described.
  • A 64-year-old male developed a left parotid gland, well-encapsulated tumor measuring 3.5 x 3 cm(2), showing mature fat cells associated with oncocytic changes of epithelial components.
  • Immunohistochemistry showed a dual epithelial population with ductal (positivity for AE1/AE3, CK19, CK7 antibodies) and basal-cell (positivity for p63, CK14, CK5,6 antibodies) differentiation in oncocytic areas.
  • [MeSH-major] Adenoma / pathology. Parotid Neoplasms / pathology
  • [MeSH-minor] Disease-Free Survival. Humans. Immunohistochemistry. Lipoma / metabolism. Lipoma / pathology. Lipoma / surgery. Male. Middle Aged. Neoplasm Proteins / metabolism

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  • [Copyright] Copyright 2009 Elsevier GmbH. All rights reserved.
  • (PMID = 19346081.001).
  • [ISSN] 1618-0631
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Neoplasm Proteins
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86. Almeida J, Mesquita M, Ferraz J, Yamanaka A, Escanhoela C, Boin IF, Pereira G, Pereira T, Soares E: Hepatocellular carcinoma developing at the puncture site after percutaneous ethanol injection. J Clin Ultrasound; 2008 Feb;36(2):105-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report a case of tumor seeding along the needle tract following PEI treatment for HCC arising 21 months after treatment.
  • [MeSH-major] Carcinoma, Hepatocellular / secondary. Ethanol / administration & dosage. Injections, Intralesional / adverse effects. Liver Neoplasms / ultrasonography. Neoplasm Seeding. Neoplasms, Adipose Tissue / secondary. Ultrasonography, Doppler, Color / methods
  • [MeSH-minor] Anti-Infective Agents, Local / administration & dosage. Anti-Infective Agents, Local / adverse effects. Diagnosis, Differential. Follow-Up Studies. Humans. Middle Aged

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  • [Copyright] (c) 2007 Wiley Periodicals, Inc.
  • (PMID = 17960825.001).
  • [ISSN] 0091-2751
  • [Journal-full-title] Journal of clinical ultrasound : JCU
  • [ISO-abbreviation] J Clin Ultrasound
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Infective Agents, Local; 3K9958V90M / Ethanol
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87. Kim HJ, Byun JH, Park SH, Shin YM, Kim PN, Ha HK, Lee MG: Focal fatty replacement of the pancreas: usefulness of chemical shift MRI. AJR Am J Roentgenol; 2007 Feb;188(2):429-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Focal fatty replacement of the pancreas: usefulness of chemical shift MRI.
  • OBJECTIVE: The purpose of this study was to describe the typical CT and chemical shift MRI findings and to evaluate their usefulness in the diagnosis of focal fatty replacement of the pancreas in five patients.
  • CONCLUSION: The presence of a perceptible focal low-attenuation lesion in the pancreas on CT and the reduction in signal intensity of the lesion on the opposed phase of chemical shift MR images are useful for differentiating focal fatty replacement of the pancreas from true pancreatic neoplasm.
  • Therefore, these imaging findings obviate invasive diagnostic procedures and surgery in the care of patients with focal fatty replacement of the pancreas.
  • [MeSH-major] Adipose Tissue / pathology. Lipomatosis / diagnosis. Magnetic Resonance Imaging / methods. Pancreatic Diseases / diagnosis. Tomography, X-Ray Computed

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  • (PMID = 17242252.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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88. Kresowik TP, Johnson MT, Joudi FN: Combined renal sinus fat and perinephric fat renal cell carcinoma invasion has a worse prognosis than either alone. J Urol; 2010 Jul;184(1):48-52
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  • Patients with von Hippel-Lindau disease were excluded from study.
  • Cox logistic regression analysis was used to control for metastatic disease, tumor size and renal vein involvement to determine differences among the groups.
  • [MeSH-major] Adipose Tissue / pathology. Carcinoma, Renal Cell / pathology. Kidney Neoplasms / pathology. Neoplasm Invasiveness / pathology
  • [MeSH-minor] Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Metastasis. Neoplasm Recurrence, Local. Prognosis. Proportional Hazards Models. Renal Veins / pathology. Survival Rate

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  • [Copyright] Copyright (c) 2010 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20478592.001).
  • [ISSN] 1527-3792
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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89. Mojallal A, Saint-Cyr M, Garrido I: Autologous fat transfer: controversies and current indications for breast surgery. J Plast Reconstr Aesthet Surg; 2009 May;62(5):708-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adipose Tissue / transplantation. Breast Neoplasms / surgery. Mammaplasty / methods
  • [MeSH-minor] Algorithms. Cell Transformation, Neoplastic. Female. Humans. Neoplasm Recurrence, Local / etiology

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  • [CommentOn] J Plast Reconstr Aesthet Surg. 2008 Dec;61(12):1438-48 [18848513.001]
  • (PMID = 19250897.001).
  • [ISSN] 1878-0539
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] Netherlands
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90. Talwalkar SS, Shaheen SP 2nd: Extra-adrenal myelolipoma in the renal hilum: a case report and review of the literature. Arch Pathol Lab Med; 2006 Jul;130(7):1049-52
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  • We report a myelolipoma presenting as a localized mass in perirenal adipose tissue juxtaposed to the renal hilum in a 65-year-old Caucasian man who presented with back pain, weight loss, hematuria, and flank pain.
  • However, histology revealed mainly mature adipose tissue along with multiple scattered islands of hematopoietic precursor cells.
  • Perirenal masses such as morphologically identified myelolipomas are rarely, if ever, considered in differential diagnosis.
  • The purpose of this report is to elicit consideration of extra-adrenal myelolipoma when formulating a differential diagnosis for perirenal and retroperitoneal tumors.
  • Although primary and secondary malignant retroperitoneal tumors are much more common and aggressive neoplasms, establishing the correct diagnosis has important therapeutic and prognostic implications.
  • [MeSH-major] Adipose Tissue / pathology. Myelolipoma / pathology. Retroperitoneal Neoplasms / pathology
  • [MeSH-minor] Aged. Angiomyolipoma / diagnosis. Carcinoma, Renal Cell / diagnosis. Carcinoma, Transitional Cell / diagnosis. Diagnosis, Differential. Humans. Kidney Neoplasms / diagnosis. Lipomatosis / diagnosis. Liposarcoma / diagnosis. Male. Neoplasm Metastasis / diagnosis. Nephrectomy. Treatment Outcome

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  • (PMID = 16831034.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
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91. Güvenç BH, Etus V, Muezzinoglu B: Lumbar teratoma presenting intradural and extramedullary extension in a neonate. Spine J; 2006 Jan-Feb;6(1):90-3
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  • Total removal of the tumor was achieved.
  • The pathological examination showed a benign teratoma containing mature cartilage, muscle, adipose tissue, and glandular tissue.
  • CONCLUSION: Accompanying a spinal dysraphic state, the mature teratoma in our case may support the idea of a tumor actually arising from a dysraphism and growing outward to produce the mass.
  • [MeSH-major] Lumbar Vertebrae. Neoplasm Invasiveness / pathology. Spinal Cord Neoplasms / diagnosis. Spinal Neoplasms / diagnosis. Teratoma / diagnosis
  • [MeSH-minor] Biopsy, Needle. Female. Follow-Up Studies. Humans. Immunohistochemistry. Infant, Newborn. Magnetic Resonance Imaging. Neoplasm Staging. Neurosurgical Procedures / methods. Recovery of Function. Risk Assessment

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  • (PMID = 16413454.001).
  • [ISSN] 1529-9430
  • [Journal-full-title] The spine journal : official journal of the North American Spine Society
  • [ISO-abbreviation] Spine J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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92. Luebke T, Baldus SE, Zirbes TK, Pham TD, Schneider PM, Dienes HP, Hölscher AH, Mönig SP: Lymph node revealing solution in gastric carcinoma does not provide upstaging of the N-status. Oncol Rep; 2005 Feb;13(2):361-5
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  • [Title] Lymph node revealing solution in gastric carcinoma does not provide upstaging of the N-status.
  • However, very small lymph nodes can easily be missed during routine examination as they are obscured by the surrounding adipose tissue.
  • The purpose of the present study was to verify the usefulness of a lymph node revealing solution (LNRS) in gastric cancer and compare its accuracy concerning the detection of lymph node metastases to immunostaining with cytokeratin antibodies.
  • The remaining tissue was immersed for 24 h in LNRS.
  • The conventional preparation of lymph nodes from the unfixed tissue yielded a total of 452 lymph nodes (mean 41.1 lymph nodes/patient; range, 26 to 56), and 201 of them had a pN0 status.
  • After application of the LNRS lymph node analysis, it was not necessary to change the UICC node (N) stage in any cases.
  • In one patient, 10 micrometastases/disseminated tumour cells were detected.
  • By performing standardized LAD systematically and detailed lymph node preparation by the pathologist, a routine application of the LNRS method in gastric carcinoma is not recommended.
  • Immunohistochemical techniques aid in identifying micrometastatic disease in lymph nodes missed in routine H&E staining in order to define the pN(i) status according to the TNM classification.
  • [MeSH-major] Acetic Acid. Adenocarcinoma / pathology. Ethanol. Ether. Formaldehyde. Neoplasm Staging. Stomach Neoplasms / pathology
  • [MeSH-minor] Humans. Immunohistochemistry / methods. Keratins / immunology. Lymphatic Metastasis / diagnosis. Reproducibility of Results

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  • Hazardous Substances Data Bank. FORMALDEHYDE .
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  • Hazardous Substances Data Bank. ACETIC ACID .
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  • (PMID = 15643525.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / lymph node revealing solution; 0F5N573A2Y / Ether; 1HG84L3525 / Formaldehyde; 3K9958V90M / Ethanol; 68238-35-7 / Keratins; Q40Q9N063P / Acetic Acid
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93. Colella G, Biondi P, Caltabiano R, Vecchio GM, Amico P, Magro G: Giant intramuscular lipoma of the tongue: a case report and literature review. Cases J; 2009;2:7906
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  • A 75-year-old Italian male presented at our department with a large tumor at the tip of the tongue that had been present for over 30 years.
  • Histological examination showed an unencapsulated lipomatous tumor composed of mature adipocytes, uniform in size and shape, diffusely infiltrating striated muscle fibers of the tongue.

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  • [Cites] J Oral Maxillofac Surg. 1991 Nov;49(11):1231-6 [1941342.001]
  • [Cites] Cancer. 1974 Mar;33(3):732-8 [4815576.001]
  • [Cites] J Oral Maxillofac Surg. 1996 Jul;54(7):915-7 [8676242.001]
  • [Cites] Br J Oral Maxillofac Surg. 1996 Dec;34(6):520-3 [8971447.001]
  • [Cites] J Oral Maxillofac Surg. 2000 Jul;58(7):817-9 [10883702.001]
  • [Cites] Ann Otol Rhinol Laryngol. 2000 Jul;109(7):683-6 [10903052.001]
  • [Cites] Quintessence Int. 2009 Jan;40(1):79-85 [19159027.001]
  • [Cites] Med Oral. 2004 Mar-Apr;9(2):166-7, 163-6 [14990884.001]
  • [Cites] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004 Oct;98(4):441-50 [15472660.001]
  • [Cites] Dent Clin North Am. 2005 Jan;49(1):223-40, x [15567370.001]
  • [Cites] Med Oral Patol Oral Cir Bucal. 2006 Aug;11(5):E437-9 [16878062.001]
  • [Cites] Otolaryngol Head Neck Surg. 2007 Nov;137(5):830-1 [17967655.001]
  • [Cites] Int J Oral Maxillofac Surg. 2003 Feb;32(1):49-53 [12653233.001]
  • (PMID = 19830025.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3302006
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94. Futagami A, Aoki M, Kawana S: A case of peripheral T-cell lymphoma unspecified involving subcutaneous tissue. Leuk Lymphoma; 2005 May;46(5):785-8
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  • [Title] A case of peripheral T-cell lymphoma unspecified involving subcutaneous tissue.
  • Histologically, the lesion showed a diffuse and dense infiltration of atypical lymphocytes extending from the superficial dermis to the subcutaneous tissue.
  • Severe lobular panniculitis, composed of small- and medium-sized atypical lymphocytes and large normal histiocytes, was observed in the subcutaneous adipose tissue.
  • [MeSH-major] Lymphoma, T-Cell, Peripheral / diagnosis. Neoplasm Regression, Spontaneous. Skin Neoplasms / diagnosis
  • [MeSH-minor] Adult. Blotting, Southern. Diagnosis, Differential. Humans. Immunohistochemistry. Immunophenotyping. Male. Skin / pathology. Subcutaneous Tissue / pathology

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  • (PMID = 16019520.001).
  • [ISSN] 1042-8194
  • [Journal-full-title] Leukemia & lymphoma
  • [ISO-abbreviation] Leuk. Lymphoma
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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95. Welsh SJ, Khan S: Radiological localizing techniques in adrenal tumors. Minerva Endocrinol; 2009 Jun;34(2):161-9
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  • [Title] Radiological localizing techniques in adrenal tumors.
  • We also discuss the radiological characteristics of rarer adrenal lesions including lymphoma, neuroblastic tumours (neuroblastoma, ganglioneuroblastoma, and ganglioneuroma), lipomatous tumours (myelolipoma, angiolipoma, teratoma, lipoma and liposarcoma), in addition to hemangioma, hemangiosarcoma and leiomyosarcoma.
  • [MeSH-major] Adrenal Gland Neoplasms / radiography. Incidental Findings. Tomography, X-Ray Computed
  • [MeSH-minor] Adrenal Cortex Neoplasms / radiography. Adrenocortical Adenoma / radiography. Adrenocortical Carcinoma / radiography. Diagnosis, Differential. Ganglioneuroblastoma / radiography. Ganglioneuroma / radiography. Humans. Lymphoma / radiography. Magnetic Resonance Imaging. Neoplasm Metastasis. Neoplasms, Adipose Tissue / radiography. Neoplasms, Vascular Tissue / radiography. Neuroblastoma / radiography. Pheochromocytoma / radiography. Predictive Value of Tests. Sensitivity and Specificity. Teratoma / radiography

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  • (PMID = 19471240.001).
  • [ISSN] 0391-1977
  • [Journal-full-title] Minerva endocrinologica
  • [ISO-abbreviation] Minerva Endocrinol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 42
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96. Bedke J, Buse S, Pritsch M, Macher-Goeppinger S, Schirmacher P, Haferkamp A, Hohenfellner M: Perinephric and renal sinus fat infiltration in pT3a renal cell carcinoma: possible prognostic differences. BJU Int; 2009 May;103(10):1349-54
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  • OBJECTIVE: To evaluate the influence of perinephric (PN) and renal sinus (RS) fat infiltration on cancer-specific survival beyond other prognostic factors, as the Tumour-Node-Metastasis (TNM) classification system defines stage T3a renal cell carcinoma (RCC) as infiltration of perirenal fat and/or direct infiltration of the adrenal gland.
  • Perirenal fat invasion is differentiated into RS and PN fat infiltration, but not further classified for the prognosis.
  • To identify prognostic effects of PN, RS or RS + PN fat infiltration, univariable and multivariable Cox proportional hazard regression models were applied, including lymph node status, metastases, presence of sarcomatoid features and tumour necrosis, Fuhrman's grade, Karnofsky performance status, and tumour size.
  • [MeSH-major] Adipose Tissue / pathology. Carcinoma, Renal Cell / pathology. Kidney Neoplasms / pathology. Nephrectomy / methods
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Epidemiologic Methods. Female. Humans. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Staging. Prognosis

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  • (PMID = 19076147.001).
  • [ISSN] 1464-410X
  • [Journal-full-title] BJU international
  • [ISO-abbreviation] BJU Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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97. Kawamoto S, Siegelman SS, Bluemke DA, Hruban RH, Fishman EK: Focal fatty infiltration in the head of the pancreas: evaluation with multidetector computed tomography with multiplanar reformation imaging. J Comput Assist Tomogr; 2009 Jan-Feb;33(1):90-5
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  • [Title] Focal fatty infiltration in the head of the pancreas: evaluation with multidetector computed tomography with multiplanar reformation imaging.
  • Fatty infiltration of the pancreas is generally a diffuse process; however, it may be unevenly distributed in the pancreas.
  • Focal fatty infiltration of the pancreas is usually most prominent in the anterior aspect of the head of the pancreas and seen as a region of decreased attenuation on computed tomography and may simulate pancreatic neoplasm.
  • We discuss and illustrate the various features of focal fatty infiltration of the pancreas on multidetector row helical computed tomography with multiplanar reformation images and show how this imaging modality helps to differentiate between focal fatty infiltration of the pancreas and actual pancreatic tumors.
  • [MeSH-major] Adipose Tissue / pathology. Adipose Tissue / radiography. Pancreas / radiography. Pancreatic Diseases / radiography. Radiographic Image Enhancement / methods. Tomography, X-Ray Computed / methods

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  • (PMID = 19188793.001).
  • [ISSN] 1532-3145
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 27
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98. Saldanha-Araujo F, Haddad R, Zanette DL, De Araujo AG, Orellana MD, Covas DT, Zago MA, Panepucci RA: Cancer/Testis antigen expression on mesenchymal stem cells isolated from different tissues. Anticancer Res; 2010 Dec;30(12):5023-7
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  • [Title] Cancer/Testis antigen expression on mesenchymal stem cells isolated from different tissues.
  • BACKGROUND/AIMS: The expression of cancer/testis antigens (CTAs) on additional normal tissues or stem cells may restrict their use as cancer targets.
  • The objective of the present study was to evaluate the mRNA levels of some CTAs in a variety of tissues.
  • MATERIALS AND METHODS: mRNA of pericytes, fibroblasts and mesenchymal stem cells (MSCs) derived from adult and fetal tissues, human umbilical vein endothelial cells, MSC-derived adipocytes, selected normal tissues and control cancer cell lines (CLs) were extracted and quantitative polymerase chain reaction was performed for MAGED1, PRAME, CTAG1B, MAGEA3 and MAGEA4.
  • RESULTS: MAGED1 was expressed in all normal tissues and cells evaluated.
  • CTAG1B was expressed at levels comparable to control CLs on MSCs derived from arterial, fetal skin, adipose tissue and saphenous vein, heart, brain and skin tissues.
  • [MeSH-major] Antigens, Neoplasm / biosynthesis. Mesenchymal Stromal Cells / immunology
  • [MeSH-minor] Fibroblasts / immunology. Humans. Immunophenotyping. Melanoma-Specific Antigens. Membrane Proteins / biosynthesis. Neoplasm Proteins / biosynthesis. Pericytes / immunology

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  • (PMID = 21187485.001).
  • [ISSN] 1791-7530
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / CTAG1B protein, human; 0 / MAGEA1 protein, human; 0 / MAGEA3 protein, human; 0 / MAGEA4 protein, human; 0 / MAGED1 protein, human; 0 / Melanoma-Specific Antigens; 0 / Membrane Proteins; 0 / Neoplasm Proteins; 0 / PRAME protein, human
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99. Aftab S, Casey A, Tirabosco R, Kabir SR, Saifuddin A: Fat-forming solitary fibrous tumour (lipomatous haemangiopericytoma) of the spine: case report and literature review. Skeletal Radiol; 2010 Oct;39(10):1039-42
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  • [Title] Fat-forming solitary fibrous tumour (lipomatous haemangiopericytoma) of the spine: case report and literature review.
  • Solitary fibrous tumour (SFT) is a rare soft tissue tumour of uncertain histogenesis and unpredictable biological behaviour, which was first described in the pleura and subsequently in many extra-pleural locations.
  • We present the clinical, radiological and histological features of a case of intraspinal fat-forming SFT, along with a literature review.
  • This is the first known report of a fat-forming SFT in the spine.
  • [MeSH-major] Solitary Fibrous Tumors / diagnosis. Spinal Neoplasms / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Follow-Up Studies. Hemangiopericytoma / diagnosis. Hemangiopericytoma / surgery. Humans. Lipoma / diagnosis. Lipoma / surgery. Magnetic Resonance Imaging / methods. Male. Rectal Neoplasms / diagnosis. Rectal Neoplasms / surgery. Treatment Outcome

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  • [Cites] Clin Exp Ophthalmol. 2002 Aug;30(4):281-3 [12121369.001]
  • [Cites] Histopathology. 2003 Oct;43(4):406-8 [14511266.001]
  • [Cites] Am J Surg Pathol. 1995 Jul;19(7):748-56 [7793472.001]
  • [Cites] Ultrastruct Pathol. 2007 Jan-Feb;31(1):51-61 [17455098.001]
  • [Cites] Pediatr Dev Pathol. 1999 Jul-Aug;2(4):346-52 [10347278.001]
  • [Cites] Radiology. 1985 Nov;157(2):479-83 [4048459.001]
  • [Cites] Urology. 2005 Jan;65(1):175 [15667897.001]
  • [Cites] Neurosurgery. 2002 Mar;50(3):654-7 [11841738.001]
  • [Cites] Dakar Med. 1998;43(1):13-20 [9827148.001]
  • [Cites] Eye (Lond). 2009 Jun;23(6):1479-81 [18617906.001]
  • [Cites] Br J Radiol. 2009 Feb;82(974):e23-6 [19168684.001]
  • [Cites] Spine (Phila Pa 1976). 2002 Apr 1;27(7):E189-92 [11923676.001]
  • [Cites] Otol Neurotol. 2006 Jun;27(4):560-3 [16791050.001]
  • [Cites] Pathologica. 2006 Dec;98(6):645-8 [17285842.001]
  • [Cites] Eur J Surg Oncol. 1996 Jun;22(3):303-5 [8654618.001]
  • [Cites] Breast J. 2005 May-Jun;11(3):211 [15871709.001]
  • [Cites] Eur J Surg Oncol. 1997 Aug;23(4):282-5 [9315052.001]
  • [Cites] Pathologe. 1990 Nov;11(6):346-9 [2290793.001]
  • [Cites] Spine (Phila Pa 1976). 2000 Jul 1;25(13):1733-5 [10870153.001]
  • [Cites] Neurosurgery. 1996 Aug;39(2):397-9; discussion 399-400 [8832681.001]
  • [Cites] Joint Bone Spine. 2008 Jul;75(4):482-5 [18487067.001]
  • [Cites] Eur Spine J. 2005 Aug;14 (6):613-8 [15864668.001]
  • (PMID = 20628877.001).
  • [ISSN] 1432-2161
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] Lipomatous hemangiopericytoma
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100. Mukai M, Nakamura M, Kishima K, Ninomiya H, Nomura N, Sato H, Kato N, Machida T, Nakasaki H, Makuuchi H: Local recurrence and occult neoplastic cells in the extranodal fat of dissected lymph nodes in patients with curatively resected primary colorectal cancer. Oncol Rep; 2007 Jun;17(6):1365-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adipose Tissue / pathology. Colorectal Neoplasms / pathology. Colorectal Neoplasms / surgery. Lymph Nodes / pathology. Neoplasm Recurrence, Local / epidemiology

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  • (PMID = 17487392.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
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