[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 100 of about 488
1. Souques M, Lassalle M, Guldner L, Asselain B, Barres D, Pavis C, Dubois G, Martin E, Fléjou JF: Colorectal polyps and cancers diagnosed by pathologists in Ile de France Region. Crisapif-Petri Study. Gastroenterol Clin Biol; 2006 Apr;30(4):587-93
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Colorectal polyps and cancers diagnosed by pathologists in Ile de France Region. Crisapif-Petri Study.
  • OBJECTIVES: The aim of this study was to evaluate the histological characteristics of adenomatous polyps (AP), non adenomatous polyps (NAP), and colorectal cancers (CRC) diagnosed in the greater Paris area.
  • MATERIAL AND METHODS: Pathologists filled out an identification and histological questionnaire for each biopsy or surgical specimen received between 20/09/02 and 20/12/02, which had at least one colorectal polyp or CRC, taken from a patient of the greater Paris area.
  • The mean number of polyps per patient was 1.4, and increased with age.
  • Average size of AP was larger than that of NAP and the size increased with age for AP but not NAP. pTNM staging of CRC was: pT0, 1% pT1, 4% pT2, 13% pT3, 63% pT4, 19% N0, 55% N1, 24% N2, 19% Nx, 2%.
  • CONCLUSION: This study provides detailed data on colorectal polyps and colorectal cancers in the greater Paris region, which does not have a cancer registry.
  • [MeSH-major] Adenomatous Polyps / epidemiology. Adenomatous Polyps / pathology. Colonic Polyps / epidemiology. Colonic Polyps / pathology. Colorectal Neoplasms / epidemiology. Colorectal Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16733383.001).
  • [ISSN] 0399-8320
  • [Journal-full-title] Gastroentérologie clinique et biologique
  • [ISO-abbreviation] Gastroenterol. Clin. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] France
  •  go-up   go-down


2. Wassenaar MJ, Cazemier M, Biermasz NR, Pereira AM, Roelfsema F, Smit JW, Hommes DW, Felt-Bersma RJ, Romijn JA: Acromegaly is associated with an increased prevalence of colonic diverticula: a case-control study. J Clin Endocrinol Metab; 2010 May;95(5):2073-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: We screened reports of colonoscopies performed for the purpose of screening for polyps in 107 patients with cured or biochemically controlled acromegaly and in 214 age- and sex-matched controls for the presence of diverticula, dolichocolon, and polyps.
  • RESULTS: In acromegaly, colonic diverticula were present in 37% of patients, dolichocolon in 34%, and adenomatous polyps in 34%, which was increased compared with controls (odds ratio 3.6, 95% confidence interval 1.4, 5.7; 12.4, 95% confidence interval 6.8, 18.0; 4.1, 95% confidence interval 1.9, 6.4, respectively).
  • The presence of colonic diverticula was associated with both GH and IGF-I concentrations at the time of diagnosis of acromegaly, when adjusted for the duration of active disease.
  • The presence of dolichocolon and adenomatous polyps was associated with higher IGF-I concentrations at diagnosis.
  • [MeSH-minor] Adenomatous Polyposis Coli / epidemiology. Adenomatous Polyposis Coli / surgery. Aging. Biopsy. Case-Control Studies. Colon, Sigmoid / pathology. Colonic Polyps / epidemiology. Colonic Polyps / surgery. Colonoscopy. Confidence Intervals. Dietary Fiber / deficiency. Female. Growth Hormone / blood. Humans. Male. Prevalence. Reference Values. Risk Factors


3. Barreda B F, Combe G J, Valdez P LA, Sánchez L J: [Clinical aspects in polyps of the colon]. Rev Gastroenterol Peru; 2007 Apr-Jun;27(2):131-47
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clinical aspects in polyps of the colon].
  • INTRODUCTION: The colonics polyps according to their number, size, location, age of presentation and mainly, according to their histology, have the potentiality of malignant degeneration, which makes of a continuous study and pursuit susceptible.
  • OBJECTIVES: To evaluate the relation between the histologic type of the colon polyps, its location, the degree of dysplasia, the size, its possible commitment by carcinoma, the age, sex and the handling that has occurred them, in a series of 684 patients of the National Institute of Enfermedades Neoplásicas (INEN) between the 1 of January from 1974 to the 31 of March of the 2004.
  • MATERIAL AND METHODS: The revision of clinical histories of 840 patients with the diagnosis of colon polyp was made who attended the service of Gastroenterology of the INEN between the 1 of January from 1974 to the 31 of March of 2004 and a card predesigned for each clinical history filled.
  • 1162 resecteds polyps evaluated themselves in this period.
  • 156 patients by diagnosis related to cancer and familiar adenomatouspoliposis did not include themselves.
  • The final sample was of 684 patients, in whom it was 1057 polyps.
  • RESULTS: 1057 polyps extirpated, by means of the endoscopy polipectomy were 1016, with colectomy were 32 and with transanal resection without colectomy they 9.
  • Within the histology of the 1057 polyps, 331 was briefed (31.3%) that were hyperplasic, 448 (42.4%) adenomas, 278 (26.3%) others and 35 (8.2%) adenocarcinomas on adenomas.
  • Adenocarcinoma (carcinomas on adenomas), was present mainly in polyps villous type, with dysplasia severe and greater to 10 mm.
  • Nevertheless, in smaller polyps of 5mm with dysplasia severe, was a polyp invaded by cancer, that represents the 0,8% of millimetric polyps.
  • The made handling was mainly endoscopic, with 96% of the resected polyps this way, also slogan transanal resection and segmental colonic resection.
  • The colectomy was necessary in 3% of all the made interventions, dysplasia severe or carcinoma was made in adenomatous polyps with, and in greater percentage in greater polyps of 20 mm (53%).
  • On the other hand, in polyps with level of invasion Haggitt 3 and 4, the colectomy was the election treatment.
  • CONCLUSIONS: The Evaluation of colonic polyps in INEN is predominantly by endoscopy.
  • The polyps are more frequent over the 50 years and have preferred location in the left colon.
  • The carcinoma is more probable with severe dysplasia and greater size of the adenoma.
  • All polyps, from the millimetric ones, including the hyperplasic, must be considered marks of neoplasia and extirpated in its totality.
  • [MeSH-major] Colonic Polyps / pathology. Colonic Polyps / surgery

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17712391.001).
  • [ISSN] 1022-5129
  • [Journal-full-title] Revista de gastroenterología del Perú : órgano oficial de la Sociedad de Gastroenterología del Perú
  • [ISO-abbreviation] Rev Gastroenterol Peru
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Peru
  •  go-up   go-down


Advertisement
4. Schatzkin A: Problems with using biomarkers as surrogate end points for cancer: a cautionary tale. Recent Results Cancer Res; 2005;166:89-98
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Inferences to cancer from such downstream markers as colorectal adenomatous polyps and persistent human papillomavirus infection of the cervix are strong, though not absolutely unassailable.
  • [MeSH-minor] Disease Progression. Humans

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15648185.001).
  • [ISSN] 0080-0015
  • [Journal-full-title] Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer
  • [ISO-abbreviation] Recent Results Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 14
  •  go-up   go-down


5. Heiken JP: CT colonography screening: ready for prime time? Cancer Imaging; 2009;9 Spec No A:S59-62
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Although multiple prospective randomized trials and observational studies have demonstrated that mortality from colon cancer can be reduced with screening and removal of adenomatous polyps, compliance with screening guidelines remains low.
  • Recent CT colonography (CTC) trials have shown that CTC is capable of demonstrating adenomatous polyps > or =10 mm (and in most cases > or = 6 mm) with sensitivities comparable to those for optical colonoscopy.
  • [MeSH-major] Adenocarcinoma / radiography. Adenoma / radiography. Colonic Neoplasms / radiography. Colonic Polyps / radiography. Colonography, Computed Tomographic
  • [MeSH-minor] Adenomatous Polyps / radiography. Aged. Colonoscopy / adverse effects. Expert Testimony. Humans. Insurance Coverage. Mass Screening. Medicaid. Medicare. Middle Aged. Multicenter Studies as Topic. Patient Compliance. Practice Guidelines as Topic. Randomized Controlled Trials as Topic / statistics & numerical data. Sensitivity and Specificity. United States

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] N Engl J Med. 2000 Nov 30;343(22):1603-7 [11096167.001]
  • [Cites] CA Cancer J Clin. 2009 Jul-Aug;59(4):225-49 [19474385.001]
  • [Cites] Am J Gastroenterol. 2002 Jun;97(6):1296-308 [12094842.001]
  • [Cites] J Natl Cancer Inst. 2003 Feb 5;95(3):230-6 [12569145.001]
  • [Cites] Gastroenterology. 2003 Apr;124(4):911-6 [12671887.001]
  • [Cites] Eur Radiol. 2003 Jun;13(6):1297-302 [12764645.001]
  • [Cites] N Engl J Med. 2003 Dec 4;349(23):2191-200 [14657426.001]
  • [Cites] JAMA. 2004 Apr 14;291(14):1713-9 [15082698.001]
  • [Cites] Cancer. 2004 May 15;100(10):2093-103 [15139050.001]
  • [Cites] Radiology. 2004 Aug;232(2):611-20 [15215541.001]
  • [Cites] N Engl J Med. 1992 Mar 5;326(10):653-7 [1736103.001]
  • [Cites] Lancet. 1996 Nov 30;348(9040):1467-71 [8942774.001]
  • [Cites] Lancet. 1996 Nov 30;348(9040):1472-7 [8942775.001]
  • [Cites] Am J Med. 1999 Jan 25;106(1A):7S-10S [10089107.001]
  • [Cites] Lancet. 2005 Jan 22-28;365(9456):305-11 [15664225.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2005 Feb;14(2):409-16 [15734966.001]
  • [Cites] Radiology. 2005 Aug;236(2):519-26 [16040909.001]
  • [Cites] Am J Gastroenterol. 2005 Dec;100(12):2771-6 [16393234.001]
  • [Cites] AJR Am J Roentgenol. 2006 Mar;186(3):718-28 [16498099.001]
  • [Cites] Clin Gastroenterol Hepatol. 2006 Mar;4(3):343-8 [16527698.001]
  • [Cites] Radiology. 2006 May;239(2):457-63 [16543590.001]
  • [Cites] Radiology. 2006 May;239(2):464-71 [16569789.001]
  • [Cites] Radiology. 2006 May;239(2):313-6 [16641348.001]
  • [Cites] Cancer. 2007 Jun 1;109(11):2213-21 [17455218.001]
  • [Cites] N Engl J Med. 2007 Oct 4;357(14):1403-12 [17914041.001]
  • [Cites] AJR Am J Roentgenol. 2008 Jan;190(1):136-44 [18094303.001]
  • [Cites] Gastroenterology. 2008 May;134(5):1570-95 [18384785.001]
  • [Cites] Radiology. 2008 Oct;249(1):151-9 [18796673.001]
  • [Cites] N Engl J Med. 2008 Sep 18;359(12):1207-17 [18799557.001]
  • [Cites] Gastroenterology. 2008 Oct;135(4):1100-5 [18691580.001]
  • [Cites] Ann Intern Med. 2008 Nov 4;149(9):627-37 [18838716.001]
  • [Cites] Gut. 2009 Feb;58(2):241-8 [18852257.001]
  • [Cites] Radiology. 2000 May;215(2):353-7 [10796907.001]
  • [Cites] Gastroenterology. 2009 Mar;136(3):1121-2; author reply 122-3 [19167389.001]
  • [Cites] Am J Gastroenterol. 2009 Mar;104(3):739-50 [19240699.001]
  • [Cites] Am J Prev Med. 2009 Jul;37(1):8-16 [19442479.001]
  • [Cites] JAMA. 2009 Jun 17;301(23):2453-61 [19531785.001]
  • [Cites] Radiology. 2002 Jul;224(1):25-33 [12091658.001]
  • (PMID = 19965295.001).
  • [ISSN] 1470-7330
  • [Journal-full-title] Cancer imaging : the official publication of the International Cancer Imaging Society
  • [ISO-abbreviation] Cancer Imaging
  • [Language] eng
  • [Publication-type] Comparative Study; Lectures
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2797457
  •  go-up   go-down


6. Ibrahim OO, Anjorin AS, Afolayan AE, Badmos KB: Pathological characterization of colorectal polyps in Ilorin, Nigeria. Afr J Med Med Sci; 2010 Sep;39(3):215-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pathological characterization of colorectal polyps in Ilorin, Nigeria.
  • Colorectal polyps especially the adenomas are recognized precursors of colorectal carcinoma.
  • Identification and removal of such polyps before malignant transformation could reduce the burden of colorectal carcinoma.
  • To document the demography and the histopathological types ofcolorectal polyps received by the Department of Pathology of University of Ilorin Teaching Hospital over a period of thirty years.
  • This is a retrospective review of all cases ofcolorectal polyps that were received, processed and had histological diagnosis in our centre between 1979 and 2008 using the request cards and hematoxylin and eosin stained slides.
  • Forty-four cases of colorectal polyps were reviewed constituting 6.7 percent of all colorectal biopsies/resections received in the same period.
  • Seventeen (38.6%) were adenomas, 9 (20.5%) were juvenile polyps, 8 (18.2%) were inflammatory polyps, 4 cases were lipomatous polyps, 3 were leiomatous polyps, and one each of lymphoid polyp, hamartomatous polyp and neurofibromatous polyp.
  • Of the adenomas, 11 (58.8%) were tubular, 5 (29.4%) were villous, 1 (5.9%) was tubulovillous, and one was a villous adenoma with a focus of malignant transformation.
  • Adenomatous polyp is the commonest pathological type ofcolorectal polyps in our centre.
  • This study therefore sets out to review the age and sex distribution, location and morphological characteristics of all cases of colorectal polyps in our centre over the study period.
  • [MeSH-major] Adenocarcinoma / pathology. Colonic Polyps / pathology. Colorectal Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21416791.001).
  • [ISSN] 0309-3913
  • [Journal-full-title] African journal of medicine and medical sciences
  • [ISO-abbreviation] Afr J Med Med Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nigeria
  •  go-up   go-down


7. Sousa-Júnior EC, Alencar AP, da Silva BB: Analysis of Ki-67 and Bcl-2 protein expression in normal colorectal mucosa of women with breast cancer. Eur J Cancer; 2009 Nov;45(17):3081-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The aim of this study was to evaluate Ki-67 and Bcl-2 protein expression in the normal colorectal mucosa adjacent to adenomatous polyps in women with breast cancer.
  • A cross-sectional, controlled study was conducted in 35 women with and without breast cancer who had adenomatous colorectal polyps.
  • A sample of normal colonic mucosa was collected at a distance of 5 cm from the polypoid lesion to evaluate immunohistochemical expression of the Ki-67 and Bcl-2 proteins.
  • [MeSH-major] Adenomatous Polyposis Coli / metabolism. Breast Neoplasms / metabolism. Intestinal Mucosa / metabolism. Ki-67 Antigen / metabolism. Neoplasm Proteins / metabolism. Proto-Oncogene Proteins c-bcl-2 / metabolism

  • Genetic Alliance. consumer health - Colorectal Cancer.
  • Genetic Alliance. consumer health - Breast Cancer.
  • MedlinePlus Health Information. consumer health - Breast Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19786344.001).
  • [ISSN] 1879-0852
  • [Journal-full-title] European journal of cancer (Oxford, England : 1990)
  • [ISO-abbreviation] Eur. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Ki-67 Antigen; 0 / Neoplasm Proteins; 0 / Proto-Oncogene Proteins c-bcl-2
  •  go-up   go-down


8. Rehani B, Chasen RM, Dowdy Y, Bharija A, Satter M, Strohmeyer P, Mantil J: Advanced adenoma diagnosis with FDG PET in a visibly normal mucosa: a case report. J Med Case Rep; 2007;1:99
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Advanced adenoma diagnosis with FDG PET in a visibly normal mucosa: a case report.
  • BACKGROUND: An accurate, early diagnosis and treatment of adenomatous polyp can curtail progression to colorectal cancer.
  • Motivated by the PET scan finding, the colonoscopist performed a biopsy which revealed a villous adenoma without high grade dysplasia.
  • Pathology from tissue extracted during an exploratory laparatomy completed one month later found the lesion to be a villous adenoma with high grade dysplasia.
  • CONCLUSION: Whole-body FDG PET scan revealed the biochemical metabolic changes in malignancy that preceded the appearance of any gross anatomical abnormality.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Ann Nucl Med. 2005 Jun;19(4):331-4 [16097645.001]
  • [Cites] Am J Gastroenterol. 2006 Dec;101(12):2711-6 [17227517.001]
  • [Cites] Hepatogastroenterology. 2007 Jan-Feb;54(73):67-70 [17419233.001]
  • [Cites] Gastroenterology. 1997 Jan;112(1):24-8 [8978338.001]
  • [Cites] Radiol Clin North Am. 1997 Mar;35(2):457-85 [9087214.001]
  • [Cites] AJR Am J Roentgenol. 2005 Aug;185(2):495-500 [16037527.001]
  • [Cites] Am J Prev Med. 1998 May;14(4):374-6 [9635089.001]
  • [Cites] Endoscopy. 2004 Jun;36(6):499-503 [15202045.001]
  • [Cites] Endoscopy. 2003 Jun;35(6):506-10 [12783349.001]
  • [Cites] Radiology. 2002 Sep;224(3):783-7 [12202714.001]
  • [Cites] Eur J Nucl Med. 2001 Dec;28(12):1766-9 [11734913.001]
  • [Cites] In Vivo. 2001 Jul-Aug;15(4):299-301 [11695221.001]
  • [Cites] J Clin Oncol. 2005 Jun 1;23(16):3713-7 [15923568.001]
  • (PMID = 17883865.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2040155
  •  go-up   go-down


9. Vakhrushev IaM, Kniazeva BG: [The peculiarities of the contents of the gastric mucus in patients with gastric polyps]. Klin Med (Mosk); 2007;85(4):49-52
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The peculiarities of the contents of the gastric mucus in patients with gastric polyps].
  • Complex study of the components of the gastric mucus in 60 patients with gastric polyps was studied.
  • The degree of the changes in the gastric mucus was higher in patients with adenomatous polyps vs. hyperplastic ones.
  • [MeSH-major] Gastric Mucosa / pathology. Mucus. Polyps / pathology. Stomach Diseases / pathology

  • MedlinePlus Health Information. consumer health - Stomach Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17564039.001).
  • [ISSN] 0023-2149
  • [Journal-full-title] Klinicheskaia meditsina
  • [ISO-abbreviation] Klin Med (Mosk)
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
  • [Chemical-registry-number] 0 / Glycosaminoglycans
  •  go-up   go-down


10. Ghelase F, Mogoş DS, Mărgăritescu D, Iordache S, Ghelase MS, Râmboiu S, Mogoş G, Bică M, Săftoiu A, Georgescu I: [Correlation of adenomatous polyps and early colorectal cancer. Diagnostic and therapeutic implications]. Chirurgia (Bucur); 2009 Mar-Apr;104(2):159-65
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Correlation of adenomatous polyps and early colorectal cancer. Diagnostic and therapeutic implications].
  • AIM: To detect the patients with colorectal adenomatous polyps or those with adenocarcinoma areas with a view to prevent and to treat the malignant disease.
  • MATERIAL AND METHOD: A prospective study including 309 patients hospitalized between 2000-2005 diagnosed with isolated adenomatous polyps after repeated colonoscopies.
  • The research method was selective screening with identification of risk factors regarding the evolution of colorectal polyps in early cancer, using colonoscopy and histopathological examination.
  • RESULTS: We identified 464 single or multiple isolated polyps of which 399 were adenomas, 59 hyperplastic polyps and 6 other types of lesions.
  • Histologically we recorded 41 (13.27%) polyps with a low grade of dysplasia, 56 (18.12%) with severe dysplasia and 30 (9.7%) intramucosal adenocarcinoma with submucosal invasion.
  • TREATMENT: Colonoscopic polypectomy was used for benign polyps and in situ carcinoma.
  • CONCLUSIONS: High grade of dysplasia, the number of polyps, ulceration, bleeding, intraepithelial areas of neoplastic transformation are predictive factors for early colorectal cancer.
  • Depth of submucosal invasion of malignant transformed polyps are important pathological factors to predict lymphatic metastasis and to select the therapeutic procedure.
  • [MeSH-major] Adenomatous Polyps / diagnosis. Adenomatous Polyps / surgery. Colectomy / methods. Colonoscopy. Colorectal Neoplasms / diagnosis. Colorectal Neoplasms / surgery
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / surgery. Carcinoma in Situ / diagnosis. Carcinoma in Situ / surgery. Cell Transformation, Neoplastic / pathology. Colonic Polyps / diagnosis. Colonic Polyps / surgery. Female. Humans. Male. Prospective Studies. Risk Factors. Treatment Outcome

  • Genetic Alliance. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19499658.001).
  • [ISSN] 1221-9118
  • [Journal-full-title] Chirurgia (Bucharest, Romania : 1990)
  • [ISO-abbreviation] Chirurgia (Bucur)
  • [Language] rum
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Romania
  •  go-up   go-down


11. Rozen P, Comaneshter D, Levi Z, Hazazi R, Vilkin A, Maoz E, Birkenfeld S, Niv Y: Cumulative evaluation of a quantitative immunochemical fecal occult blood test to determine its optimal clinical use. Cancer; 2010 May 1;116(9):2115-25
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The objective was to evaluate sensitivity and specificity for CRC and advanced adenomatous polyps (APs) by the fecal Hb threshold used to determine a positive test and the number of IFOBTs prepared per test, so as to determine the least number of colonoscopies required to detect a neoplasm.
  • Limitations are 1-time screening and most examinees not being at average risk for CRC.
  • [MeSH-major] Adenomatous Polyps / diagnosis. Colorectal Neoplasms / diagnosis. Occult Blood
  • [MeSH-minor] Colonic Polyps / diagnosis. Colonoscopy. Early Detection of Cancer. Hemoglobins / analysis. Humans. Immunohistochemistry. Middle Aged. Predictive Value of Tests. Sensitivity and Specificity

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2010 American Cancer Society.
  • (PMID = 20186820.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Hemoglobins
  •  go-up   go-down


12. Hao Y, Jemal A, Zhang X, Ward EM: Trends in colorectal cancer incidence rates by age, race/ethnicity, and indices of access to medical care, 1995–2004 (United States). Cancer Causes Control; 2009 Dec;20(10):1855-63
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This is largely thought to reflect increases in utilization of CRC screening through detection and removal of adenomatous polyps.
  • RESULTS: Among whites, CRC incidence rates decreased significantly from 1998 through 2004 in age ≥ 65, but not in age 50-64 in counties with high uninsured or poverty rates, fewer PCPs, or in nonmetro areas.
  • Among African Americans or Hispanics, rates did not decrease in age 50-64 in general and age ≥ 65 in counties with high poverty rates, low PCP supply, and nonmetro counties (African Americans).
  • Colorectal endoscopic screening rates increased significantly among whites in both age groups, but not among Hispanics (aged 50-64 in general and aged ≥ 65 residing in high poverty counties) or African Americans residing in counties with higher uninsured rates (age 50-64), low PCP supply, high poverty rates, and nonmetro counties (age ≥ 65).
  • CONCLUSIONS: Our results suggest that individuals residing in poorer communities with lower access to medical care have not experienced the reduction in CRC incidence rates that have benefited more affluent communities; these disparities may be related to health care access barriers to colorectal endoscopic screening.

  • Genetic Alliance. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Health Disparities.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19543799.001).
  • [ISSN] 1573-7225
  • [Journal-full-title] Cancer causes & control : CCC
  • [ISO-abbreviation] Cancer Causes Control
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  •  go-up   go-down


13. Martínez ME, Jacobs ET, Ashbeck EL, Sinha R, Lance P, Alberts DS, Thompson PA: Meat intake, preparation methods, mutagens and colorectal adenoma recurrence. Carcinogenesis; 2007 Sep;28(9):2019-27
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Meat intake, preparation methods, mutagens and colorectal adenoma recurrence.
  • We prospectively assessed the relation between type of meat, meat preparation method, doneness, a metric of HCAs and other mutagens and colorectal adenoma recurrence among 869 participants in a chemoprevention trial of ursodeoxycholic acid.
  • Most meat variables assessed were positively but weakly associated with recurrence of any adenoma.
  • Our results support a meat mutagen exposure hypothesis as a potential mechanism for recurrence of clinically significant adenomatous polyps.
  • [MeSH-major] Adenoma / epidemiology. Colorectal Neoplasms / epidemiology. Cooking / methods. Meat / analysis. Mutagens / analysis

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17690112.001).
  • [ISSN] 0143-3334
  • [Journal-full-title] Carcinogenesis
  • [ISO-abbreviation] Carcinogenesis
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA-23074; United States / NCI NIH HHS / CA / CA-41108; United States / NCI NIH HHS / CA / CA106269; United States / NCI NIH HHS / CA / CA95060
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anticarcinogenic Agents; 0 / Mutagens; 724L30Y2QR / Ursodeoxycholic Acid
  •  go-up   go-down


14. Lee SS, Park SH, Choi EK, Kim SY, Kim MJ, Lee KH, Kim YH: Colorectal polyps on portal phase contrast-enhanced CT colonography: lesion attenuation and distinction from tagged feces. AJR Am J Roentgenol; 2007 Jul;189(1):35-40
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Colorectal polyps on portal phase contrast-enhanced CT colonography: lesion attenuation and distinction from tagged feces.
  • OBJECTIVE: The purpose of our study was to determine the attenuation of colorectal polyps on portal phase contrast-enhanced CT colonography (CTC) and evaluate whether enhanced polyps can be clearly distinguished from tagged feces during CTC review.
  • Forty-eight colonoscopy-proven polyps (6-20 mm) and 41 polypoid tagged feces (6-19 mm) were selected from contrast-enhanced CTC performed without (n = 37 examinations) and with (n = 10 examinations) fecal tagging, respectively.
  • Attenuation of the polyps and tagged feces was measured.
  • Four independent blinded radiologists reviewed the polyps and tagged feces at both wide (width, 1,500 H; level -400 H) and soft-tissue (width, 400 H; level, 20 H) window settings to distinguish them by using subjective visual assessment.
  • RESULTS: Polyp attenuation on the portal phase was not correlated with size (R = -0.003; p = 0.99) and was not different between histologic types (p = 0.884).
  • Enhanced polyps (mean +/- SD, 119.9 +/- 25.3 H; range, 50-173 H) showed significantly lower attenuation than did tagged feces (1,521.4 +/- 683.6 H; range, 495-2,683 H) without any overlap (p < 0.0005).
  • An 8-mm sessile adenomatous polyp was misinterpreted as tagged feces by one reviewer.
  • CONCLUSION: Polyp attenuation on portal phase contrast-enhanced CTC ranges from 50 to 173 H.
  • Contrast-enhanced polyps are clearly and consistently distinguished from barium-tagged polypoid feces.
  • [MeSH-major] Colonic Polyps / radiography. Colonography, Computed Tomographic / methods. Contrast Media / administration & dosage. Feces. Radiographic Image Enhancement / methods. Rectal Diseases / radiography

  • MedlinePlus Health Information. consumer health - Bowel Movement.
  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Rectal Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17579149.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
  •  go-up   go-down


15. Nowicki MJ, Bishop PR, Subramony C, Wyatt-Ashmead J, May W, Crawford M: Colonic chicken-skin mucosa in children with polyps is not a preneoplastic lesion. J Pediatr Gastroenterol Nutr; 2005 Nov;41(5):600-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Colonic chicken-skin mucosa in children with polyps is not a preneoplastic lesion.
  • Colonic polyps are common both in adults and children; however, the malignant potential varies according to the type of polyp.
  • Most childhood polyps are solitary juvenile polyps, which have negligible malignant potential.
  • Chicken-skin mucosa (CSM) is an endoscopic finding initially described associated with adenomatous polyps and adenocarcinoma, suggesting a preneoplastic lesion.
  • Subsequently, CSM was described in association with juvenile polyps, suggesting that this mucosal finding is not a precursor to dysplasia.
  • The association of CSM with benign juvenile polyps and the absence of histologic markers for increased replication and malignant transformation support the notion that this endoscopic finding is not preneoplastic.
  • Rather, CSM arises in proximity to polyps of all histologic types because of local mucosal damage.
  • [MeSH-major] Colonic Neoplasms / pathology. Colonic Polyps / pathology. Intestinal Mucosa / pathology. Ki-67 Antigen / metabolism. Tumor Suppressor Protein p53 / metabolism
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / metabolism. Adenocarcinoma / pathology. Adenoma / diagnosis. Adenoma / metabolism. Adenoma / pathology. Biomarkers, Tumor / analysis. Biopsy. Child. Child, Preschool. Colon / pathology. Colonoscopy. Female. Humans. Immunohistochemistry. Male. Prospective Studies

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16254516.001).
  • [ISSN] 0277-2116
  • [Journal-full-title] Journal of pediatric gastroenterology and nutrition
  • [ISO-abbreviation] J. Pediatr. Gastroenterol. Nutr.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 0 / Tumor Suppressor Protein p53
  •  go-up   go-down


16. Gryfe R: Overview of colorectal cancer genetics. Surg Oncol Clin N Am; 2009 Oct;18(4):573-83
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Cancer is a genetic disease in which the clonal accumulation of genetic alterations confers a cell with the malignant characteristics of uncontrolled growth, local invasiveness, and metastastic potential.
  • Studies of colorectal cancer and its precursor lesion, the adenomatous polyp, have served as the cornerstone in advancing knowledge of cancer molecular genetics.

  • Genetic Alliance. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19793566.001).
  • [ISSN] 1558-5042
  • [Journal-full-title] Surgical oncology clinics of North America
  • [ISO-abbreviation] Surg. Oncol. Clin. N. Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Neoplasm Proteins
  • [Number-of-references] 81
  •  go-up   go-down


17. Gupta S: Colorectal polyps: the scope and management of the problem. Am J Med Sci; 2008 Nov;336(5):407-17
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Colorectal polyps: the scope and management of the problem.
  • Much of the benefit of colorectal cancer screening has been attributed to detection and removal of adenomatous polyps, highlighting the importance of colorectal polyps as targets for intervention and as biomarkers for colorectal cancer risk.
  • This review details the epidemiology of sporadic colorectal polyps, rationale behind use of polyps as an important surrogate for colorectal cancer risk, the benefits and limitations of secondary prevention of colorectal polyps through chemopreventive and dietary interventions, as well as colon surveillance.
  • [MeSH-major] Colonic Polyps / diagnosis. Colonic Polyps / surgery. Colorectal Neoplasms / diagnosis. Colorectal Neoplasms / prevention & control
  • [MeSH-minor] Adenoma / diagnosis. Adenoma / epidemiology. Adenoma / pathology. Adenoma / prevention & control. Congresses as Topic. Cyclooxygenase Inhibitors / therapeutic use. Diet. Humans. Mass Screening. Middle Aged. Risk Factors. Sigmoidoscopy

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19011398.001).
  • [ISSN] 0002-9629
  • [Journal-full-title] The American journal of the medical sciences
  • [ISO-abbreviation] Am. J. Med. Sci.
  • [Language] eng
  • [Grant] United States / NCRR NIH HHS / RR / 1 KL2 RR024983-01
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cyclooxygenase Inhibitors
  •  go-up   go-down


18. Dhar A, Johnson KS, Novelli MR, Bown SG, Bigio IJ, Lovat LB, Bloom SL: Elastic scattering spectroscopy for the diagnosis of colonic lesions: initial results of a novel optical biopsy technique. Gastrointest Endosc; 2006 Feb;63(2):257-61
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We assessed the diagnostic potential of ESS in the colon to differentiate normal colonic mucosa, chronic colitis, hyperplastic polyps, adenomatous polyps (with dysplasia), and adenocarcinoma.
  • They were then compared with conventional biopsy specimens taken from the same site, including normal colonic mucosa, hyperplastic polyps, adenomatous polyps, chronic colitis, and colon cancer.
  • RESULTS: A total of 483 spectra were analyzed (290 normal, 19 hyperplastic, 69 adenomatous polyps, 74 chronic colitis, and 31 colorectal cancer).
  • The sensitivity and the specificity of differentiating adenomas from hyperplastic polyps was 84% and 84%, respectively; for cancer from adenomatous polyps, 80% and 75%, respectively; for colitis from normal tissue, 77% and 82%, respectively; and for dysplastic mucosa (from polyps) from colitis, 85% and 88%, respectively.
  • It could prove a valuable aid for targeting biopsies in dysplasia surveillance in inflammatory bowel disease and for deciding which small polyps should be removed.

  • MedlinePlus Health Information. consumer health - Biopsy.
  • MedlinePlus Health Information. consumer health - Colonic Diseases.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16427931.001).
  • [ISSN] 0016-5107
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


19. Zhou PH, Yao LQ, Chen WF: [Endoscopic therapy of adenomatous polyps and early-stage carcinomas of the colon and rectum]. Zhonghua Wai Ke Za Zhi; 2008 Sep 15;46(18):1386-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Endoscopic therapy of adenomatous polyps and early-stage carcinomas of the colon and rectum].
  • OBJECTIVE: To assess the clinical efficacy of endoscopic treatment for colorectal adenomatous polyps and early-stage carcinomas.
  • METHODS: Between January 2006 and October 2007, 245 patients with colorectal adenomatous polyps and early-stage carcinomas with lifting sign(+) were treated by such endoscopic techniques as polypectomy, endoscopic mucosal resection (EMR), endoscopic piecemeal mucosal resection (EPMR) and endoscopic submucosal dissection (ESD).
  • CONCLUSIONS: Endoscopic resection appears to be an efficacious procedure to treat adenomatous polyp and early-stage carcinoma and provide pathological information about the whole lesion.
  • [MeSH-major] Adenomatous Polyps / surgery. Colorectal Neoplasms / surgery. Endoscopes, Gastrointestinal

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19094508.001).
  • [ISSN] 0529-5815
  • [Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]
  • [ISO-abbreviation] Zhonghua Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  •  go-up   go-down


20. Konda A, Duffy MC: Surveillance of patients at increased risk of colon cancer: inflammatory bowel disease and other conditions. Gastroenterol Clin North Am; 2008 Mar;37(1):191-213, viii
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surveillance of patients at increased risk of colon cancer: inflammatory bowel disease and other conditions.
  • Colonoscopic screening with removal of adenomatous polyps in individuals at average risk is known to decrease the incidence and associated mortality from colon cancer.
  • Certain conditions, notably inflammatory bowel disease involving the colon, a family history of polyps or cancer, a personal history of colon cancer or polyps, and other conditions such as acromegaly, ureterosigmoidostomy, and Streptococcus bovis bacteremia are associated with an increased risk of colonic neoplasia.

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18313546.001).
  • [ISSN] 0889-8553
  • [Journal-full-title] Gastroenterology clinics of North America
  • [ISO-abbreviation] Gastroenterol. Clin. North Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 157
  •  go-up   go-down


21. Tam YH, Lee KH, Chan KW, Sihoe JD, Cheung ST, Mou JW: Colonoscopy in Hong Kong Chinese children. World J Gastroenterol; 2010 Mar 7;16(9):1119-22
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • AIM: To investigate the safety and diagnostic yield of colonoscopy in Chinese children in whom the procedure is not often done.
  • Forty patients (50.6%) had a positive diagnosis made in colonoscopy and that included colonic polyps (23), Crohn's disease (12), ulcerative colitis (1), and miscellaneous causes (4).
  • 80% of polyps were in the rectosigmoid colon.
  • All but one were juvenile hamartomatous polyps.
  • The exception was an adenomatous polyp.
  • The mean ages for children with inflammatory bowel disease (IBD) and polyps were 11.3 and 4.3 years respectively.
  • The increasing diagnosis of IBD in recent decades may reflect a rising incidence of the disease in our children.
  • [MeSH-major] Colonic Polyps / diagnosis. Colonoscopy. Inflammatory Bowel Diseases / diagnosis

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Pediatr Gastroenterol Nutr. 1999;29 Suppl 1:S1-26 [10554139.001]
  • [Cites] J Pediatr Gastroenterol Nutr. 2008 May;46(5):539-45 [18493209.001]
  • [Cites] Lancet. 2001 Apr 7;357(9262):1093-4 [11297962.001]
  • [Cites] Am J Gastroenterol. 2001 Jun;96(6):1695-7 [11419816.001]
  • [Cites] J Pediatr. 2003 Oct;143(4):525-31 [14571234.001]
  • [Cites] J Pediatr Gastroenterol Nutr. 2003 Nov;37(5):609-13 [14581806.001]
  • [Cites] Gut. 2004 Feb;53(2):277-83 [14724164.001]
  • [Cites] Pediatrics. 1984 May;73(5):594-9 [6718114.001]
  • [Cites] Am J Gastroenterol. 1986 May;81(5):312-4 [3706244.001]
  • [Cites] J Pediatr Surg. 1987 Apr;22(4):332-4 [3494835.001]
  • [Cites] Gut. 1989 May;30(5):618-22 [2786488.001]
  • [Cites] J Pediatr Surg. 1992 Sep;27(9):1220-2 [1432534.001]
  • [Cites] J Pediatr Gastroenterol Nutr. 1994 Oct;19(3):283-9 [7815258.001]
  • [Cites] Arch Dis Child. 1996 May;74(5):460-1 [8669968.001]
  • [Cites] Scand J Gastroenterol. 1996 May;31(5):417-27 [8734336.001]
  • [Cites] Gastroenterol Clin North Am. 1995 Sep;24(3):467-74 [8809231.001]
  • [Cites] Am J Gastroenterol. 1998 Apr;93(4):619-22 [9576458.001]
  • [Cites] Pediatrics. 1998 Aug;102(2 Pt 1):381-3 [9685442.001]
  • [Cites] J Pediatr Gastroenterol Nutr. 1999 Feb;28(2):175-81 [9932851.001]
  • [Cites] Acta Paediatr. 1999 Feb;88(2):199-202 [10102155.001]
  • [Cites] Lancet. 1999 May 1;353(9163):1496-7 [10232323.001]
  • [Cites] J Pediatr Gastroenterol Nutr. 2006 Nov;43(5):699-701 [17130753.001]
  • [Cites] Eur J Gastroenterol Hepatol. 2007 Apr;19(4):317-20 [17353696.001]
  • [Cites] Clin Gastroenterol Hepatol. 2008 May;6(5):515-20 [18356115.001]
  • [Cites] J Pediatr Gastroenterol Nutr. 2000 Mar;30(3):259-64 [10749408.001]
  • (PMID = 20205284.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2835790
  •  go-up   go-down


22. Głuszko P, Bielińska A: Non-steroidal anti-inflammatory drugs and the risk of cardiovascular diseases: are we going to see the revival of cyclooxygenase-2 selective inhibitors? Pol Arch Med Wewn; 2009 Apr;119(4):231-5
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In 2004 and 2005, predictions of some pharmacologists were confirmed when the Adenomatous Polyp Prevention on VIOXX trial (APPROVE) and other randomized, double-blind, placebo-controlled trials with COX-2 inhibitors showed an increased rate of thrombotic vascular events, including myocardial infarction, in patients treated with coxibs.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19413182.001).
  • [Journal-full-title] Polskie Archiwum Medycyny Wewnetrznej
  • [ISO-abbreviation] Pol. Arch. Med. Wewn.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; 0 / Cyclooxygenase 2 Inhibitors
  • [Number-of-references] 23
  •  go-up   go-down


23. Mitrou PN, Watson MA, Loktionov AS, Cardwell C, Gunter MJ, Atkin WS, Macklin CP, Cecil T, Bishop TD, Primrose J, Bingham SA: MTHFR (C677T and A1298C) polymorphisms and risk of sporadic distal colorectal adenoma in the UK Flexible Sigmoidoscopy Screening Trial (United Kingdom). Cancer Causes Control; 2006 Aug;17(6):793-801
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] MTHFR (C677T and A1298C) polymorphisms and risk of sporadic distal colorectal adenoma in the UK Flexible Sigmoidoscopy Screening Trial (United Kingdom).
  • OBJECTIVE: The purpose of this study was to further evaluate the role of low activity MTHFR variants as well as to explore interactive effects between alcoholic drink consumption and MTHFR variants and risk of distal colorectal adenomatous polyps.
  • METHODS: We examined the relationship between MTHFR C677T and A1298C gene polymorphisms and risk of distal adenomas in one of the largest case control studies of 946 polyp-free controls and 894 cases, all participants of the UK Flexible Sigmoidoscopy Screening Trial (UKFSS).
  • RESULTS: Investigation of the effect of the MTHFR C677T polymorphism in this large UKFSS study revealed no overall association on adenoma risk (P>0.05).
  • CONCLUSIONS: In this, the largest study of these polymorphisms in relation to colorectal adenoma, there was no evidence for an interaction with alcohol in combination with the variant forms of MTHFR (P>0.05).
  • [MeSH-major] 5,10-Methylenetetrahydrofolate Reductase (FADH2) / genetics. Adenoma / genetics. Adenomatous Polyps / genetics. Colorectal Neoplasms / genetics. Polymorphism, Single Nucleotide / genetics
  • [MeSH-minor] Aged. Alcohol Drinking. Case-Control Studies. Female. Gene Frequency. Genetic Predisposition to Disease. Humans. Male. Mass Screening. Middle Aged. Risk Factors. Sigmoidoscopy / methods

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16783607.001).
  • [ISSN] 0957-5243
  • [Journal-full-title] Cancer causes & control : CCC
  • [ISO-abbreviation] Cancer Causes Control
  • [Language] eng
  • [Grant] United Kingdom / Cancer Research UK / / A4994; United Kingdom / Medical Research Council / / G9615910
  • [Publication-type] Journal Article; Multicenter Study; Randomized Controlled Trial
  • [Publication-country] Netherlands
  • [Chemical-registry-number] EC 1.5.1.20 / 5,10-Methylenetetrahydrofolate Reductase (FADH2)
  •  go-up   go-down


24. Rastogi A, Pondugula K, Bansal A, Wani S, Keighley J, Sugar J, Callahan P, Sharma P: Recognition of surface mucosal and vascular patterns of colon polyps by using narrow-band imaging: interobserver and intraobserver agreement and prediction of polyp histology. Gastrointest Endosc; 2009 Mar;69(3 Pt 2):716-22
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Recognition of surface mucosal and vascular patterns of colon polyps by using narrow-band imaging: interobserver and intraobserver agreement and prediction of polyp histology.
  • BACKGROUND: The 2 main types of colon polyps are adenomas and hyperplastic.
  • Pit patterns on the surface of polyps have been described by using magnification chromoendoscopy, which can help differentiate between polyp types.
  • Narrow band imaging (NBI) is a novel technology that enhances the visualization of surface mucosal and vascular patterns on the polyp surface.
  • Earlier we described, in a pilot study, patterns seen on the polyp surface with NBI that can help differentiate between adenomas and hyperplastic polyps with a high degree of accuracy.
  • OBJECTIVE: The aim of this study was to evaluate the interobserver and intraobserver agreement (among endoscopists) for the NBI surface mucosal and vascular patterns and prediction of polyp histology and the accuracy of the investigators to predict polyp histology based on these patterns.
  • METHODS: NBI images of the polyp surface mucosal and vascular patterns obtained in our pilot trial were retrieved.
  • A teaching set of 20 images was selected to educate and demonstrate the polyp patterns to 4 endoscopists.
  • Subsequently, the test set of images was evaluated by the 4 endoscopists for quality, polyp pattern, and prediction of polyp type.
  • Interobserver agreement (k value) was calculated among the 4 assessors for the polyp patterns and predicted histology.
  • By using the final histology as the criterion standard, the accuracy of polyp-type prediction was calculated for each assessor.
  • After a period of 2 months, all polyp images were reevaluated by the assessors (as before), and all findings were recorded in a similar fashion.
  • These results were used for calculation of intraobserver agreement (k value) and the accuracy of the assessors in predicting polyp type.
  • RESULTS: Photographs of 65 polyps were included in the test set and were evaluated by the 4 assessors.
  • Thirty-eight polyps were adenomatous, and 27 were hyperplastic.
  • The kappa value for the interobserver agreement for polyp surface pattern was 0.57 (moderate) and for prediction of polyp type was 0.63 (substantial).
  • The kappa value for the intraobserver agreement of the 4 assessors for the surface patterns was 0.70, 0.65, 0.60, and 0.79, and for the prediction of polyp type was 0.87, 0.71, 0.61, 0.81.
  • The accuracy to predict polyp type ranged from 80% to 86% for the 4 assessors in the first reading and from 85% to 91% in the second reading, with every assessor showing an improvement in accuracy in the second reading.
  • LIMITATIONS: A single-center study, with a limited number of polyps.
  • CONCLUSIONS: This initial evaluation showed that the NBI polyp patterns described in our pilot study are reproducible, easy to learn, reasonably accurate, and have the potential for use in daily clinical practice for the real-time differentiation of colon polyps.
  • [MeSH-major] Colonic Polyps / pathology. Colonoscopy / statistics & numerical data

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Gastrointest Endosc. 2009 Mar;69(3 Pt 2):723-5 [19251017.001]
  • (PMID = 19251016.001).
  • [ISSN] 1097-6779
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


25. Oh K, Redston M, Odze RD: Support for hMLH1 and MGMT silencing as a mechanism of tumorigenesis in the hyperplastic-adenoma-carcinoma (serrated) carcinogenic pathway in the colon. Hum Pathol; 2005 Jan;36(1):101-11
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Support for hMLH1 and MGMT silencing as a mechanism of tumorigenesis in the hyperplastic-adenoma-carcinoma (serrated) carcinogenic pathway in the colon.
  • This mechanism has also recently been implicated in the newly postulated hyperplastic polyp-serrated adenoma-carcinoma ("serrated") pathway of carcinogenesis, although this has never been investigated thoroughly.
  • The aim of this study was to evaluate hMLH1, hMSH2, MGMT, as well as MIB-1, p53, and beta-catenin immunoexpression in an uncommon cohort of mixed colonic polyps that contain a combination of hyperplastic and adenomatous features (n = 21), and in some (n = 7), carcinoma as well.
  • DESIGN: The clinical, pathological, and immunophenotypic (hMLH1, hMSH2, MGMT, MIB-1, p53, and beta-catenin) properties of 28 mixed hyperplastic and adenomatous polyps of the colon (7 of which also contained carcinoma within the same lesion) were evaluated for the above immunopeptides in each of the different morphologic areas of the polyps, and the results were compared to traditional hyperplastic polyps, serrated adenomas, and conventional (nonserrated) adenomas.
  • RESULTS: Clinically, most mixed polyps with carcinoma occurred in the ascending colon (86%), and pathologically, the adenomatous component of most mixed polyps was serrated (96%).
  • Mixed polyps, particularly those with carcinoma, showed loss of hMLH1 (33%), MGMT (37%), and even hMSH2 (11%) with significantly higher frequency compared to hyperplastic polyps, conventional adenomas, and serrated adenomas.
  • More specifically, loss of hMLH1 and MGMT were more frequent in epithelium of higher neoplastic grade in mixed polyps.
  • However, hMSH2 loss was only present in the adenoma component and never in the hyperplastic or carcinomatous areas of these polyps.
  • Defects in MIB-1 proliferation indices and p53 were not significantly different among the same epithelial components in each of the polyp groups.
  • However, conventional adenomas showed significantly higher rates of nuclear beta -catenin staining (100%) in comparison to the adenomatous component of mixed polyps (60%).
  • [MeSH-major] Cell Transformation, Neoplastic / genetics. Colonic Neoplasms / genetics. Colonic Polyps / genetics. Gene Silencing. Neoplasm Proteins / genetics. O(6)-Methylguanine-DNA Methyltransferase / genetics
  • [MeSH-minor] Adaptor Proteins, Signal Transducing. Adenoma / genetics. Adenoma / metabolism. Adenoma / pathology. Adult. Aged. Aged, 80 and over. Carcinoma / genetics. Carcinoma / metabolism. Carcinoma / pathology. Carrier Proteins. Cytoskeletal Proteins / metabolism. DNA-Binding Proteins / genetics. DNA-Binding Proteins / metabolism. Female. Humans. Hyperplasia / genetics. Hyperplasia / metabolism. Hyperplasia / pathology. Immunohistochemistry. Ki-67 Antigen / metabolism. Male. Middle Aged. MutS Homolog 2 Protein. Nuclear Proteins. Proto-Oncogene Proteins / genetics. Proto-Oncogene Proteins / metabolism. Trans-Activators / metabolism. Tumor Suppressor Protein p53 / metabolism. beta Catenin

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15712188.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Adaptor Proteins, Signal Transducing; 0 / CTNNB1 protein, human; 0 / Carrier Proteins; 0 / Cytoskeletal Proteins; 0 / DNA-Binding Proteins; 0 / Ki-67 Antigen; 0 / MLH1 protein, human; 0 / Neoplasm Proteins; 0 / Nuclear Proteins; 0 / Proto-Oncogene Proteins; 0 / Trans-Activators; 0 / Tumor Suppressor Protein p53; 0 / beta Catenin; EC 2.1.1.63 / O(6)-Methylguanine-DNA Methyltransferase; EC 3.6.1.3 / MSH2 protein, human; EC 3.6.1.3 / MutS Homolog 2 Protein
  •  go-up   go-down


26. DaCosta RS, Wilson BC, Marcon NE: Optical techniques for the endoscopic detection of dysplastic colonic lesions. Curr Opin Gastroenterol; 2005 Jan;21(1):70-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Endoscopic optical coherence tomography has now acquired real-time Doppler capabilities, and rudimentary endoscopic criteria for hyperplastic and adenomatous polyps have been described.

  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • COS Scholar Universe. author profiles.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15687888.001).
  • [ISSN] 0267-1379
  • [Journal-full-title] Current opinion in gastroenterology
  • [ISO-abbreviation] Curr. Opin. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Chromogenic Compounds
  • [Number-of-references] 89
  •  go-up   go-down


27. Ihtiyar E, Algin C, Isiksoy S, Ates E: Small cell carcinoma of rectum: a case report. World J Gastroenterol; 2005 May 28;11(20):3156-8
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • By colonoscopy, polyps were determined in the rectum and biopsies were carried out.
  • Histopathologically, the polyps were adenomatous.

  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15918209.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC4305859
  •  go-up   go-down


28. Benfatto G, Tenaglia L, Catania G, D'Antoni S, Jiryis A, Centoze D, Garufi SM, Mugavero F, Giovinetto A: Pathological evaluation in colorectal polyps endoscopic treatment. G Chir; 2006 Nov-Dec;27(11-12):411-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pathological evaluation in colorectal polyps endoscopic treatment.
  • This retrospective study shows that endoscopic polypectomy is the technique of choice to remove the majority of polyps; follow-up and pathologic examinations shed light on the carcinogenesis of colorectal lesions.
  • From January 1990 to December 2001, 1302 adenomatous polyps were removed, 1175 endoscopically, 127 with surgical procedures.
  • The anatomical and morphologic conditions of the colon and some characteristics of the polyps represent limits to the feasibility and to the efficacy of polypectomy, and the most important variables for the correct management of the patients affected by colorectal adenomatous polyps.
  • [MeSH-major] Adenomatous Polyposis Coli / pathology. Adenomatous Polyposis Coli / surgery. Endoscopy

  • MedlinePlus Health Information. consumer health - Endoscopy.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17198549.001).
  • [ISSN] 0391-9005
  • [Journal-full-title] Il Giornale di chirurgia
  • [ISO-abbreviation] G Chir
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


29. Harford WV: Colorectal cancer screening and surveillance. Surg Oncol Clin N Am; 2006 Jan;15(1):1-20, v
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Patients at increased risk for colorectal cancer, such as those with a positive family history, previous adenomatous polyps or cancer, and inflammatory bowel disease, should be offered more intensive evaluation and surveillance.

  • Genetic Alliance. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16389147.001).
  • [ISSN] 1055-3207
  • [Journal-full-title] Surgical oncology clinics of North America
  • [ISO-abbreviation] Surg. Oncol. Clin. N. Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 114
  •  go-up   go-down


30. Fernández-Suárez A, Cordero Fernández C, García Lozano R, Pizarro A, Garzón M, Núñez Roldán A: Clinical and ethical implications of genetic counselling in familial adenomatous polyposis. Rev Esp Enferm Dig; 2005 Sep;97(9):654-65
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical and ethical implications of genetic counselling in familial adenomatous polyposis.
  • The association of specific genetic disturbances with the development of hereditary cancer helps us to understand the risk of suffering from it, the possibility of an earlier diagnosis, and the treatment and prevention of this disease.
  • Familial adenomatous polyposis (FAP) is a pre-neoplastic syndrome characterized by the presence of hundreds of adenomatous polyps in the colon, which develop into a carcinoma.
  • FAP can be diagnosed using sequencing techniques to detect mutations in the germinal line of the APC (adenomatous polyposis coli) gene.
  • The genetic diagnostic approach in families with FAP, previously followed up in the Gastrointestinal Clinic, has both advantages and disadvantages, and places us nearer the disease and patient.
  • [MeSH-major] Adenomatous Polyposis Coli / prevention & control. Genetic Counseling


31. Ramos C, De Jesús-Caraballo J, Toro DH, Ojeda A, Martínez-Souss J, Dueño MI, Cruz-Correa M: Is barium enema an adequate diagnostic test for the evaluation of patients with positive fecal occult blood? Bol Asoc Med P R; 2009 Apr-Jun;101(2):23-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Secondary objectives were to determine: the diagnostic accuracy according to adenoma location, size, and pathologic characteristics; and patient satisfaction with each procedure METHODS: Cross-sectional study comparing the ac curacy of DCBE and colonoscopy in detecting adenomatous polyps and/or colorectal cancer in patients with positive FOBT.
  • Polyps identified during colonoscopy were removed and classified by histology.
  • Polyps were fou in 40/50 (80%) patients in colonoscopy, compared to 19/50 (38%) in DCBE.
  • Eighty-four percent of polyps were missed by DCBE.
  • Diagnostic accuracy of DCBE was inferior to colonoscopy, for all size polyps and larg adenomas.
  • [MeSH-major] Adenocarcinoma / radiography. Adenomatous Polyps / radiography. Barium Sulfate. Colonic Polyps / radiography. Colorectal Neoplasms / radiography. Contrast Media. Enema. Gastrointestinal Hemorrhage / radiography. Occult Blood

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Gastrointestinal Bleeding.
  • Hazardous Substances Data Bank. Barium sulfate .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19954097.001).
  • [ISSN] 0004-4849
  • [Journal-full-title] Boletín de la Asociación Médica de Puerto Rico
  • [ISO-abbreviation] Bol Asoc Med P R
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Puerto Rico
  • [Chemical-registry-number] 0 / Contrast Media; 25BB7EKE2E / Barium Sulfate
  •  go-up   go-down


32. Del Rio P, Crafa P, Papadia C, Dell'Abate P, Franzè A, Franzini G, Campanini N, Sianesi M: Evaluation of CD10 positivity in colorectal polyps in neoplastic transformation. Ann Ital Chir; 2010 Mar-Apr;81(2):121-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Evaluation of CD10 positivity in colorectal polyps in neoplastic transformation.
  • MATERIALS AND METHOD: We have correlated CD10 positive in carcinomatous polyps with tumour size, grade, patient age and sex, postoperative TNM staging and Asler-Coller classification.
  • We have matched these cases with a control group that showed presence of polypoid adenomatous tissue with mild to moderate dysplasia.
  • RESULTS: We have divided these in a group of 39 cases, characterised by the presence of carcinoma arising in adenomatous polyps, and a control group of 16 cases, characterised by the presence of colorectal polyps with mild to moderate dysplasia.
  • [MeSH-major] Cell Transformation, Neoplastic / metabolism. Colonic Polyps / metabolism. Colonic Polyps / pathology. Colorectal Neoplasms / metabolism. Colorectal Neoplasms / pathology. Neprilysin / biosynthesis. Rectal Neoplasms / metabolism. Rectal Neoplasms / pathology
  • [MeSH-minor] Aged. Case-Control Studies. Female. Humans. Intestinal Polyps / metabolism. Intestinal Polyps / pathology. Male. Retrospective Studies

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20726390.001).
  • [ISSN] 0003-469X
  • [Journal-full-title] Annali italiani di chirurgia
  • [ISO-abbreviation] Ann Ital Chir
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] EC 3.4.24.11 / Neprilysin
  •  go-up   go-down


33. Wong DC, Wong SK, Leung AL, Chung CC, Li MK: Combined endolaparoscopic intragastric excision for gastric neoplasms. J Laparoendosc Adv Surg Tech A; 2009 Dec;19(6):765-70
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The remaining lesions were adenomatous polyp with focal intramucosal adenocarcinoma, leiomyoma, and pancreatic heterotopia.
  • [MeSH-minor] Adenoma / pathology. Adenoma / surgery. Aged. Aged, 80 and over. Carcinoma / pathology. Carcinoma / surgery. Cohort Studies. Female. Humans. Leiomyoma / pathology. Leiomyoma / surgery. Male. Middle Aged. Retrospective Studies. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19645605.001).
  • [ISSN] 1557-9034
  • [Journal-full-title] Journal of laparoendoscopic & advanced surgical techniques. Part A
  • [ISO-abbreviation] J Laparoendosc Adv Surg Tech A
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


34. Clements D, Tawfiq S, Harries B, Sheridan W: Application of the BSG guidelines to a colonoscopy waiting list. Colorectal Dis; 2009 Jun;11(5):513-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • If applied less rigidly, 42% of patients should not have been on the list.
  • The reasons for removal from the list were as follows: Thirty-nine patients were older than the upper age limit, 23 had had clear colonoscopies after adenomatous polyp follow up, four were listed for diverticular disease follow up, four for metaplastic polyps, one for constipation and one for per rectum (PR) bleed follow up.
  • Conclusion With strict application of the BSG guidelines to a surveillance colonoscopy waiting list, 49% of the patients on the list do not need the procedure.

  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18637926.001).
  • [ISSN] 1463-1318
  • [Journal-full-title] Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
  • [ISO-abbreviation] Colorectal Dis
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] England
  •  go-up   go-down


35. Goode EL, Potter JD, Bamlet WR, Rider DN, Bigler J: Inherited variation in carcinogen-metabolizing enzymes and risk of colorectal polyps. Carcinogenesis; 2007 Feb;28(2):328-41
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Inherited variation in carcinogen-metabolizing enzymes and risk of colorectal polyps.
  • Exposures such as cigarette smoke and meat contain a variety of procarcinogens, which are thought to play a role in elevation of risk for colorectal polyps and/or cancer.
  • We hypothesized that genetic variation in the encoding genes NAT1, NAT2, SULT1A1, SULT1A2, CYP1A1 or EPHX1 is associated with risk of colorectal polyps and interacts with cigarette use or meat intake to modify risk of colorectal polyps.
  • We examined the role of these genes in a clinic-based study of 651 Caucasian cases with hyperplastic polyps, adenomatous polyps or both types of polyps and 556 polyp-free controls.
  • We found evidence for interaction between NAT acetylator status and SULT1A1 genotype in risk of hyperplastic polyps: individuals with SULT1A1 638AA genotype and NAT1 and NAT2 intermediate/fast phenotypes had 3.5-fold increased risk (95% CI 1.2-10.3) compared with individuals with SULT1A1 638GG genotype and NAT1 and NAT2 slow phenotypes.
  • [MeSH-major] Carcinogens / metabolism. Colonic Polyps / enzymology. Enzymes / metabolism. Genetic Variation
  • [MeSH-minor] Adult. Aged. Case-Control Studies. Genetic Predisposition to Disease. Humans. Middle Aged. Risk Factors

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16926176.001).
  • [ISSN] 0143-3334
  • [Journal-full-title] Carcinogenesis
  • [ISO-abbreviation] Carcinogenesis
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / R25-CA094880; United States / NCI NIH HHS / CA / T32-CA09661
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Carcinogens; 0 / Enzymes
  •  go-up   go-down


36. Chia VM, Newcomb PA, Lampe JW, White E, Mandelson MT, McTiernan A, Potter JD: Leptin concentrations, leptin receptor polymorphisms, and colorectal adenoma risk. Cancer Epidemiol Biomarkers Prev; 2007 Dec;16(12):2697-703
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Leptin concentrations, leptin receptor polymorphisms, and colorectal adenoma risk.
  • Obesity has been shown to be associated with an increased risk of both colorectal cancer and adenomatous polyps.
  • We conducted a gastroenterology clinic-based, case-control study to evaluate the relationship between circulating leptin concentrations and colorectal adenoma risk; in addition, we evaluated the relationship between leptin receptor polymorphisms and adenoma risk.
  • Among men, those in the highest tertile of leptin concentrations had a 3.3-fold (95% confidence interval, 1.2-8.7) increased adenoma risk compared with those in the lowest tertile (P trend = 0.01).
  • There were no associations between leptin concentrations and adenoma risk in women.
  • There were no associations of leptin receptor genotypes or haplotypes and adenoma risk.

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18086776.001).
  • [ISSN] 1055-9965
  • [Journal-full-title] Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
  • [ISO-abbreviation] Cancer Epidemiol. Biomarkers Prev.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P01CA74184; United States / NCI NIH HHS / CA / R03 CA110852; United States / NCI NIH HHS / CA / R25 CA094880; United States / NCI NIH HHS / CA / U01 CA074794; United States / NCI NIH HHS / CA / P01 CA074184; United States / NCI NIH HHS / CA / R25CA094880; United States / NCI NIH HHS / CA / R03CA11085
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Leptin; 0 / Receptors, Leptin
  •  go-up   go-down


37. Groblewska M, Mroczko B, Wereszczyńska-Siemiatkowska U, Kedra B, Lukaszewicz M, Baniukiewicz A, Szmitkowski M: Serum interleukin 6 (IL-6) and C-reactive protein (CRP) levels in colorectal adenoma and cancer patients. Clin Chem Lab Med; 2008;46(10):1423-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Serum interleukin 6 (IL-6) and C-reactive protein (CRP) levels in colorectal adenoma and cancer patients.
  • It has been shown that local chronic inflammation may lead to colorectal carcinogenesis via adenomatous polyps.
  • METHODS: Serum levels of interleukin-6, carcinoembryonic antigen and carbohydrate antigen 19-9 were determined using immunoenzymatic assays, and C-reactive protein concentrations by immunoturbidimetric kits in 76 colorectal cancer patients before surgery, in 38 colorectal adenoma patients and in 35 healthy controls.
  • RESULTS: Serum levels of interleukin-6, C-reactive protein and carcinoembryonic antigen were significantly higher in cancer patients when compared to adenoma patients and healthy subjects, and increased in more advanced stages of disease and in patients with non-resectable tumors.


38. Beaton MD, Taylor B, Driman D, Ainsworth P, Adams PC: Colonic interposition in a woman with attenuated familial adenomatosis polyposis: does the location of the colon affect polyp formation? Can J Gastroenterol; 2008 Jul;22(7):634-6
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Colonic interposition in a woman with attenuated familial adenomatosis polyposis: does the location of the colon affect polyp formation?
  • Attenuated familial adenomatous polyposis (AFAP) is a rare but well-established cause of colorectal carcinoma and multiple polyps.
  • While she had developed adenomatous polyps in her native cecum, there was no evidence of polyps or cancer in the segment of large intestine interposed between her upper esophagus and stomach.
  • [MeSH-major] Adenomatous Polyposis Coli / pathology. Colonic Polyps / pathology

  • Genetic Alliance. consumer health - Familial Polyposis.
  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Gut. 1999 Dec;45(6):829-33 [10562580.001]
  • [Cites] Transl Res. 2007 Sep;150(3):147-9 [17761365.001]
  • [Cites] Surg Today. 2001;31(11):1020-3 [11766074.001]
  • [Cites] Dis Colon Rectum. 2002 Jan;45(1):127-34; discussion 134-6 [11786778.001]
  • [Cites] Gut. 2002 May;50(5):636-41 [11950808.001]
  • [Cites] Am J Pathol. 2002 Jun;160(6):2253-7 [12057927.001]
  • [Cites] Am J Gastroenterol. 2002 Jul;97(7):1822-7 [12135043.001]
  • [Cites] J Postgrad Med. 1986 Oct;32(4):206-9 [3585794.001]
  • [Cites] Cancer. 1988 Apr 15;61(8):1563-70 [3349420.001]
  • [Cites] IARC Monogr Eval Carcinog Risks Hum. 1994;61:1-241 [7715068.001]
  • [Cites] Cancer Res. 1997 Mar 1;57(5):812-4 [9041176.001]
  • [Cites] Hum Genet. 1997 Oct;100(5-6):601-5 [9341879.001]
  • [Cites] Am J Hum Genet. 1998 Jun;62(6):1290-301 [9585611.001]
  • [Cites] Nutr Cancer. 1998;31(2):111-8 [9770722.001]
  • [Cites] N Engl J Med. 1999 Mar 18;340(11):825-31 [10080844.001]
  • [Cites] Cancer. 1999 Apr 15;85(8):1664-9 [10223558.001]
  • [Cites] World J Gastroenterol. 2006 Nov 14;12(42):6741-6 [17106919.001]
  • [Cites] Tech Coloproctol. 2006 Dec;10(4):287-96 [17115321.001]
  • [Cites] Crit Rev Oncol Hematol. 2007 Feb;61(2):153-61 [17064931.001]
  • [Cites] Cancer Res. 2001 Mar 15;61(6):2395-8 [11289103.001]
  • (PMID = 18629394.001).
  • [ISSN] 0835-7900
  • [Journal-full-title] Canadian journal of gastroenterology = Journal canadien de gastroenterologie
  • [ISO-abbreviation] Can. J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC2661270
  •  go-up   go-down


39. Halligan S, Taylor SA: CT colonography: results and limitations. Eur J Radiol; 2007 Mar;61(3):400-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Meta-analysis of data from studies of CT colonography suggests that it has excellent per-patient average sensitivity and average specificity for detection of adenomatous polyps and cancer.
  • [MeSH-major] Adenoma / radiography. Colonic Polyps / radiography. Colonography, Computed Tomographic. Colorectal Neoplasms / diagnosis. Colorectal Neoplasms / prevention & control

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17174055.001).
  • [ISSN] 0720-048X
  • [Journal-full-title] European journal of radiology
  • [ISO-abbreviation] Eur J Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Meta-Analysis; Review
  • [Publication-country] Ireland
  • [Number-of-references] 35
  •  go-up   go-down


40. Wasilewicz MP, Kołodziej B, Bojułko T, Kaczmarczyk M, Sulzyc-Bielicka V, Bielicki D, Ciepiela K: Overexpression of 5-lipoxygenase in sporadic colonic adenomas and a possible new aspect of colon carcinogenesis. Int J Colorectal Dis; 2010 Sep;25(9):1079-85
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: A total of 111 patients were examined and 120 histologically different colonic adenomas analyzed (including four cases of intramucosal adenocarcinoma in a polyp).
  • RESULTS: There was a significant correlation between high 5-LOX expression and patient age, increased polyp size, high grade of intraepithelial neoplasia, villous and tubulovillous adenoma, and histological epithelial localization.
  • CONCLUSIONS: We observed a strong positive correlation between 5-LOX overexpression and the appearance of typical high-risk factors for malignant transformation in adenomatous polyps.
  • [MeSH-major] Adenoma / enzymology. Adenoma / pathology. Arachidonate 5-Lipoxygenase / metabolism. Colonic Neoplasms / enzymology. Colonic Neoplasms / pathology. Precancerous Conditions / enzymology. Precancerous Conditions / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Carcinoma in Situ / enzymology. Carcinoma in Situ / pathology. Colonic Polyps / enzymology. Colonic Polyps / pathology. Female. Humans. Male. Middle Aged

  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Gastroenterology. 2003 Jan;124(1):57-70 [12512030.001]
  • [Cites] Int J Mol Med. 2004 Mar;13(3):389-93 [14767568.001]
  • [Cites] Clin Cancer Res. 2004 Oct 1;10(19):6703-9 [15475461.001]
  • [Cites] Korean J Gastroenterol. 2004 Oct;44(4):206-11 [15505432.001]
  • [Cites] Anticancer Res. 1998 Mar-Apr;18(2A):791-800 [9615721.001]
  • [Cites] Carcinogenesis. 1998 Aug;19(8):1393-400 [9744535.001]
  • [Cites] Prostate. 1998 Nov 1;37(3):161-73 [9792133.001]
  • [Cites] Proc Natl Acad Sci U S A. 1998 Oct 27;95(22):13182-7 [9789062.001]
  • [Cites] Int J Cancer. 1999 Nov 12;83(4):470-5 [10508481.001]
  • [Cites] J Exp Clin Cancer Res. 2005 Jun;24(2):279-87 [16110762.001]
  • [Cites] Anticancer Res. 2005 May-Jun;25(3B):2065-8 [16158946.001]
  • [Cites] Gut. 2006 Jan;55(1):54-61 [16085694.001]
  • [Cites] World J Gastroenterol. 2006 Oct 21;12(39):6355-60 [17072961.001]
  • [Cites] Clin Cancer Res. 2008 Oct 15;14(20):6525-30 [18927292.001]
  • [Cites] Am J Pathol. 2000 Feb;156(2):545-53 [10666384.001]
  • [Cites] Aliment Pharmacol Ther. 2000 Apr;14 Suppl 1:64-7 [10807405.001]
  • [Cites] Cancer. 2000 Dec 15;89(12):2637-45 [11135226.001]
  • [Cites] J Gastroenterol Hepatol. 2000 Nov;15(11):1277-81 [11129221.001]
  • [Cites] J Pathol. 2002 Dec;198(4):428-34 [12434411.001]
  • [Cites] Am J Pathol. 2002 Aug;161(2):421-8 [12163367.001]
  • [Cites] Cancer. 2001 Feb 15;91(4):737-43 [11241241.001]
  • [Cites] Pathol Int. 2002 Apr;52(4):272-6 [12031082.001]
  • [Cites] Oncogene. 2001 Feb 15;20(7):819-27 [11314016.001]
  • (PMID = 20549218.001).
  • [ISSN] 1432-1262
  • [Journal-full-title] International journal of colorectal disease
  • [ISO-abbreviation] Int J Colorectal Dis
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] EC 1.13.11.34 / Arachidonate 5-Lipoxygenase
  • [Other-IDs] NLM/ PMC2912725
  •  go-up   go-down


41. Kim JH, Lee SY, Kim BK, Choe WH, Kwon SY, Sung IK, Park HS, Jin CJ: Importance of the surrounding colonic mucosa in distinguishing between hyperplastic and adenomatous polyps during acetic acid chromoendoscopy. World J Gastroenterol; 2008 Mar 28;14(12):1903-7
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Importance of the surrounding colonic mucosa in distinguishing between hyperplastic and adenomatous polyps during acetic acid chromoendoscopy.
  • AIM: To examine the characteristics of colonic polyps, where it is difficult to distinguish adenomatous polyps from hyperplastic polyps, with the aid of acetic acid chromoendoscopy.
  • METHODS: Acetic acid spray was applied to colonic polyps smaller than 10 mm before complete excision.
  • Both pre- and post-sprayed images were shown to 16 examiners, who were asked to interpret the lesions as either hyperplastic or adenomatous polyps.
  • Regression analysis demonstrated that surrounding colonic mucosa was the only factor that was significantly related to accuracy in discriminating adenomatous from hyperplastic polyps (P < 0.001).
  • Accuracy was higher for polyps with linear surrounding colonic mucosa than for those with nodular surrounding colonic mucosa (P < 0.001), but was not related to the shape, location, or size of the polyp.
  • CONCLUSION: The accuracy of predicting histology is significantly related to the pattern of colonic mucosa surrounding the polyp.
  • Making a histological diagnosis of colon polyps merely by acetic acid spray is helpful for colon polyps with linear, regularly patterned surrounding colonic mucosa, and less so for those with nodular, irregularly patterned surrounding colonic mucosa.
  • [MeSH-major] Acetic Acid. Adenomatous Polyps. Colonic Polyps. Endoscopy / methods. Hyperplasia. Intestinal Mucosa

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Endoscopy.
  • Hazardous Substances Data Bank. ACETIC ACID .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Gastrointest Endosc. 2003 Jan;57(1):48-53 [12518130.001]
  • [Cites] Endoscopy. 2003 May;35(5):437-45 [12701018.001]
  • [Cites] Ann Surg. 1987 Jun;205(6):659-64 [3592808.001]
  • [Cites] Gastroenterology. 1996 Apr;110(4):1253-8 [8613016.001]
  • [Cites] Gastrointest Endosc. 1996 Jul;44(1):8-14 [8836710.001]
  • [Cites] Endoscopy. 2004 Dec;36(12):1089-93 [15578300.001]
  • [Cites] Gastrointest Endosc. 2002 May;55(6):687-94 [11979251.001]
  • [Cites] Gastrointest Endosc. 2006 May;63(6):824-8 [16650546.001]
  • [Cites] World J Gastroenterol. 2006 Apr 21;12(15):2402-5 [16688833.001]
  • [Cites] Gastrointest Endosc. 2006 Jun;63(7):1010-7 [16733118.001]
  • [Cites] CA Cancer J Clin. 2006 May-Jun;56(3):143-59; quiz 184-5 [16737947.001]
  • [Cites] Endoscopy. 2006 Jun;38(6):613-6 [16612744.001]
  • [Cites] Gastrointest Endosc. 2006 Jul;64(1):13-6 [16813796.001]
  • [Cites] World J Gastroenterol. 2006 Mar 7;12(9):1416-20 [16552812.001]
  • (PMID = 18350630.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] Q40Q9N063P / Acetic Acid
  • [Other-IDs] NLM/ PMC2700415
  •  go-up   go-down


42. Half EE, Arber N: Chemoprevention of colorectal cancer: two steps forward, one step back? Future Oncol; 2006 Dec;2(6):697-704
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The poor survival rate has prompted the emphasis on prevention of this disease.
  • Sulindac and celecoxib were shown to be effective in promoting polyp regression in high-risk individuals with familial adenomatous polyposis.
  • In the more common sporadic setting, the Adenomatous Polyp PRevention On Vioxx (rofecoxib), Adenoma Prevention with Celecoxib and Prevention of Sporadic Adenomatous Polyps (celecoxib) trials have demonstrated a significant reduction in adenoma recurrence, but important concerns were raised regarding cardiovascular toxicity associated with selective cyclo-oxygenase-2 inhibitors.
  • Currently, the only approved agent for chemoprevention is celecoxib in high-risk individuals with familial adenomatous polyposis.
  • [MeSH-major] Adenoma / prevention & control. Adenomatous Polyps / drug therapy. Anticarcinogenic Agents / therapeutic use. Colonic Polyps / drug therapy. Colorectal Neoplasms / prevention & control

  • Genetic Alliance. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17155896.001).
  • [ISSN] 1479-6694
  • [Journal-full-title] Future oncology (London, England)
  • [ISO-abbreviation] Future Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; 0 / Anticarcinogenic Agents; 0 / Cyclooxygenase 2 Inhibitors
  • [Number-of-references] 59
  •  go-up   go-down


43. Erdem L, Akbayir N, Yildirim S, Köksal HM, Yenice N, Gültekin OS, Sakiz D, Peker O: Predictive value of morphologic characteristics in rectosigmoid adenomatous polyps for the probability of synchronous polyps or cancer in the proximal colon. Turk J Gastroenterol; 2005 Dec;16(4):207-11
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Predictive value of morphologic characteristics in rectosigmoid adenomatous polyps for the probability of synchronous polyps or cancer in the proximal colon.
  • The necessity of colonoscopy in patients with an adenoma of<or=5 mm found on sigmoidoscopy is controversial.
  • METHODS: Patients found to have rectosigmoid adenomatous polyps on colonoscopy were included in the study.
  • These adenomas were grouped as diminutive (<or=5 mm), small (6-10 mm) or large (>or=11 mm) polyps.
  • These groups were compared regarding the presence of proximal adenoma and advanced proximal neoplasia (>10 mm adenoma and/or villous histology and/or high grade dysplasia or cancer).
  • Polyps found in the rectum and sigmoid colon were considered as distal polyps and polyps other than these were considered as proximal polyps.
  • RESULTS: In this study, of 1124 consecutive patients who underwent colonoscopy between April 1997 and January 2002, 184 (16%) had 258 adenomatous polyps in the rectosigmoid area.
  • The polyps were diminutive (<or=5 mm) in 105, small (6-10 mm) in 46 and large (>or=11 mm) in 33 patients.
  • Forty-one of the patients (39%) with diminutive polyps, 20 of the patients (43%) with small polyps and 19 of the patients (57%) with large polyps had neoplasm in the proximal bowel.
  • The rate of advanced proximal neoplasm was found to be significantly higher in the group with large polyps in the rectosigmoid area than in the groups with small and diminutive polyps (p<0.05).
  • In 104 patients (57%) with polyp(s) in rectum and sigmoid colon, no associated polyp or cancer was encountered in the proximal colon.
  • CONCLUSION: Colonoscopy is indicated when adenomatous polyp, regardless of size, is found on rectosigmoidoscopy performed because of symptoms.
  • [MeSH-major] Adenomatous Polyps / pathology. Colonic Neoplasms / pathology. Colonic Polyps / pathology. Neoplasms, Multiple Primary. Rectal Neoplasms / pathology. Sigmoid Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16547849.001).
  • [ISSN] 1300-4948
  • [Journal-full-title] The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
  • [ISO-abbreviation] Turk J Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] Turkey
  •  go-up   go-down


44. Pino MS, Mino-Kenudson M, Wildemore BM, Ganguly A, Batten J, Sperduti I, Iafrate AJ, Chung DC: Deficient DNA mismatch repair is common in Lynch syndrome-associated colorectal adenomas. J Mol Diagn; 2009 May;11(3):238-47
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The combination of MSI and IHC testing in colorectal adenomas is a sensitive screen for the detection of Lynch syndrome and may be particularly useful when Lynch syndrome is suspected and adenomatous polyps are the only tissues available for analysis.

  • Genetic Alliance. consumer health - Lynch syndrome.
  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Gastroenterology. 2004 Jan;126(1):42-8 [14699485.001]
  • [Cites] Fam Cancer. 2001;1(2):87-92 [14574003.001]
  • [Cites] Cancer. 1971 Jun;27(6):1505-11 [5088221.001]
  • [Cites] Cancer. 1991 Sep 1;68(5):1109-12 [1913482.001]
  • [Cites] Science. 1993 May 7;260(5109):816-9 [8484122.001]
  • [Cites] Nature. 1993 Jun 10;363(6429):558-61 [8505985.001]
  • [Cites] Cell. 1993 Dec 3;75(5):1027-38 [8252616.001]
  • [Cites] Science. 1994 Mar 18;263(5153):1625-9 [8128251.001]
  • [Cites] Nature. 1994 Mar 17;368(6468):258-61 [8145827.001]
  • [Cites] Nature. 1994 Sep 1;371(6492):75-80 [8072530.001]
  • [Cites] Cancer Res. 1994 Nov 1;54(21):5523-6 [7923189.001]
  • [Cites] Mutat Res. 1994 Oct 1;310(1):125-33 [7523876.001]
  • [Cites] Gastroenterology. 1996 Aug;111(2):307-17 [8690195.001]
  • [Cites] Cancer Res. 1996 Nov 1;56(21):4836-40 [8895729.001]
  • [Cites] Pathology. 1997 Feb;29(1):28-33 [9094174.001]
  • [Cites] Gut. 1997 May;40(5):660-3 [9203947.001]
  • [Cites] Gastroenterology. 1997 Oct;113(4):1146-58 [9322509.001]
  • [Cites] Nat Genet. 1997 Nov;17(3):271-2 [9354786.001]
  • [Cites] Am J Pathol. 1998 Oct;153(4):1063-78 [9777938.001]
  • [Cites] Cancer Res. 1998 Nov 15;58(22):5248-57 [9823339.001]
  • [Cites] Gut. 1999 Jun;44(6):839-43 [10323887.001]
  • [Cites] J Clin Pathol. 1999 Jan;52(1):5-9 [10343605.001]
  • [Cites] Am J Surg Pathol. 2005 Jan;29(1):96-104 [15613860.001]
  • [Cites] J Mol Diagn. 2005 May;7(2):160-70 [15858139.001]
  • [Cites] Mod Pathol. 2005 Aug;18(8):1095-101 [15731775.001]
  • [Cites] Int J Colorectal Dis. 2006 Oct;21(7):632-41 [16511680.001]
  • [Cites] JAMA. 2006 Sep 27;296(12):1507-17 [17003399.001]
  • [Cites] J Clin Oncol. 2008 Jul 10;26(20):3434-9 [18612159.001]
  • [Cites] J Med Genet. 1999 Nov;36(11):801-18 [10544223.001]
  • [Cites] J Clin Pathol. 1999 Jun;52(6):455-60 [10562815.001]
  • [Cites] Am J Pathol. 1999 Dec;155(6):1849-53 [10595914.001]
  • [Cites] Annu Rev Genet. 1999;33:533-64 [10690417.001]
  • [Cites] Curr Opin Genet Dev. 2000 Apr;10(2):157-61 [10753784.001]
  • [Cites] Gastroenterology. 2000 May;118(5):829-34 [10784581.001]
  • [Cites] Gut. 2000 Jul;47(1):37-42 [10861262.001]
  • [Cites] Gut. 2000 Aug;47(2):315-6 [10960281.001]
  • [Cites] Hum Mol Genet. 2001 Apr;10(7):735-40 [11257106.001]
  • [Cites] Lab Invest. 2001 Apr;81(4):535-41 [11304573.001]
  • [Cites] Cancer Res. 2001 Jun 1;61(11):4545-9 [11389088.001]
  • [Cites] Am J Hum Genet. 2002 Jan;70(1):26-37 [11709755.001]
  • [Cites] Gut. 2002 Feb;50(2):228-34 [11788565.001]
  • [Cites] Gut. 2002 Mar;50(3):382-6 [11839719.001]
  • [Cites] Cancer Res. 2002 Jun 15;62(12):3485-92 [12067992.001]
  • [Cites] Mod Pathol. 2002 Jul;15(7):741-9 [12118112.001]
  • [Cites] Gastroenterology. 2003 Aug;125(2):501-9 [12891553.001]
  • [Cites] Cancer Res. 2003 Aug 15;63(16):4878-81 [12941809.001]
  • [Cites] Am J Gastroenterol. 2003 Oct;98(10):2306-11 [14572584.001]
  • [Cites] Clin Cancer Res. 2004 May 1;10(9):3082-90 [15131047.001]
  • (PMID = 19324997.001).
  • [ISSN] 1943-7811
  • [Journal-full-title] The Journal of molecular diagnostics : JMD
  • [ISO-abbreviation] J Mol Diagn
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / R01 CA092594; United States / NCI NIH HHS / CA / CA92594
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2671341
  •  go-up   go-down


45. Khatibzadeh N, Ziaee SA, Rahbar N, Molanie S, Arefian L, Fanaie SA: The indirect role of site distribution in high-grade dysplasia in adenomatous colorectal polyps. J Cancer Res Ther; 2005 Oct-Dec;1(4):204-7
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The indirect role of site distribution in high-grade dysplasia in adenomatous colorectal polyps.
  • BACKGROUND: The appropriate application of Endoscopic modalities for polypectomy depends on the likelihood that the adenoma in question harbors invasive cancer.
  • While prior studies have evaluated polyp size and morphology in assessing the risk of malignancy, in recent decay some authorities have paid more attention to dysplasia.
  • All in all, the relative risk of cancer based on polyp distribution in correlation with dysplasia has not been statistically studied which is done in our study.
  • METHODS AND MATERIALS: Between June 2001 and March 2004, the distribution of 130 adenomatous polyps was compared with synchronous invasive or in situ cancer.
  • Factors such as Patient age, Patients gender, location of lesion, size of polyp, histological subtype of adenoma on biopsy, degree of dysplasia, synchronous cancer, color of polyp, and number of polyps were included in the data collection.
  • [MeSH-major] Adenomatous Polyps / pathology. Colorectal Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17998654.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  •  go-up   go-down


46. Paskett ED, Reeves KW, Pineau B, Albert PS, Caan B, Hasson M, Iber F, Kikendall JW, Lance P, Shike M, Slattery ML, Weissfeld J, Kahle L, Schatzkin A, Lanza E, Polyp Prevention Trial Study Group: The association between cigarette smoking and colorectal polyp recurrence (United States). Cancer Causes Control; 2005 Nov;16(9):1021-33
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The association between cigarette smoking and colorectal polyp recurrence (United States).
  • OBJECTIVE: Although evidence exists linking smoking to precancerous colorectal adenomatous polyps, few studies have examined the association between cigarette smoking and recurrence of colorectal polyps.
  • This association was investigated prospectively with data from the Polyp Prevention Trial.
  • Multiple logistic regression analysis was used to examine the association between cigarette smoking and polyp recurrence (adenomatous and hyperplastic) up to four years from baseline.
  • RESULTS: Adenoma recurrence was not related to cigarette smoking.
  • Current smokers had increased odds of hyperplastic polyps at follow-up compared to never smokers (OR 2.88, 95% CI 2.06-4.01).
  • Current smoking was associated with subsequent distal (OR 3.44, 95% CI 2.38-4.95) and rectal (OR 3.53, 95% CI 2.15-5.78) hyperplastic polyps, but not subsequent proximal hyperplastic polyps.
  • Cigarette smoking was associated with subsequent multiple and small size (4 mm) hyperplastic polyps.
  • Significant linear trends were observed between development of subsequent hyperplastic polyps and all smoking variables.
  • CONCLUSIONS: Although no association with recurrent adenomas was observed, cigarette smoking was significantly associated with hyperplastic polyp development, except for those in the proximal colon.
  • This prospective study confirms that cigarette smoking has a significant effect on the development of hyperplastic colorectal polyps.
  • [MeSH-major] Colonic Polyps / pathology. Precancerous Conditions. Smoking / epidemiology
  • [MeSH-minor] Adenoma / epidemiology. Adenoma / pathology. Aged. Colonoscopy. Epidemiologic Studies. Female. Humans. Hyperplasia / epidemiology. Hyperplasia / pathology. Male. Middle Aged. Recurrence. Risk Assessment. Risk Factors. Surveys and Questionnaires. Time Factors. United States

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Smoking.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16184467.001).
  • [ISSN] 0957-5243
  • [Journal-full-title] Cancer causes & control : CCC
  • [ISO-abbreviation] Cancer Causes Control
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  •  go-up   go-down


47. Guillén-Ponce C, Castillejo A, Barberá VM, Pascual-Ramírez JC, Andrada E, Castillejo MI, Guarinós C, Molina-Garrido MJ, Carrato A, Soto JL: Biallelic MYH germline mutations as cause of Muir-Torre syndrome. Fam Cancer; 2010 Jun;9(2):151-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Muir-Torre syndrome is a rare, inherited disease predisposing of gastrointestinal and cutaneous tumours, such as keratoacanthomas and sebaceous gland adenomas.
  • This report describes a man who has multiple adenomatous colon polyps, a gastric cancer, multiple colorectal cancers and sebaceous adenomas caused by biallelic MYH germline mutations.
  • This finding demonstrates that MYH gene analysis should be considered in Muir-Torre families where no mismatch repair gene mutations have been found.

  • Genetic Alliance. consumer health - Keratoacanthoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19998059.001).
  • [ISSN] 1573-7292
  • [Journal-full-title] Familial cancer
  • [ISO-abbreviation] Fam. Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  •  go-up   go-down


48. Casadesus D: Surgical resection of rectal adenoma: a rapid review. World J Gastroenterol; 2009 Aug 21;15(31):3851-4
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical resection of rectal adenoma: a rapid review.
  • Transanal excision (TE), endoscopic transanal resection (ETAR) and transanal endoscopic microsurgery (TEM) can be used to remove adenomatous polyps.
  • [MeSH-major] Adenoma. Anastomosis, Surgical. Rectal Neoplasms

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Orv Hetil. 1999 Oct 3;140(40):2215-9 [10540895.001]
  • [Cites] Dis Colon Rectum. 2008 Jul;51(7):1026-30; discussion 1030-1 [18481147.001]
  • [Cites] ANZ J Surg. 2002 Dec;72(12):854-6 [12485218.001]
  • [Cites] World J Surg. 2003 Feb;27(2):197-202 [12616436.001]
  • [Cites] Dis Colon Rectum. 2003 Oct;46(10):1345-50 [14530673.001]
  • [Cites] Ann Surg Oncol. 2003 Nov;10(9):1106-11 [14597451.001]
  • [Cites] Dis Colon Rectum. 2004 Jan;47(1):86-9 [14702647.001]
  • [Cites] Surg Endosc. 2003 Sep;17(9):1461-3 [12739115.001]
  • [Cites] JSLS. 2004 Apr-Jun;8(2):123-6 [15119655.001]
  • [Cites] J Gastroenterol Hepatol. 2004 Jul;19(7):767-72 [15209623.001]
  • [Cites] Int J Colorectal Dis. 2004 Nov;19(6):569-73 [15103489.001]
  • [Cites] Nouv Presse Med. 1974 May 25;3(21):1365-6 [4848702.001]
  • [Cites] Chirurg. 1977 May;48(5):343-4 [862483.001]
  • [Cites] Chirurg. 1984 Oct;55(10):677-80 [6510078.001]
  • [Cites] Dis Colon Rectum. 1991 Oct;34(10):880-5 [1914721.001]
  • [Cites] Br J Surg. 1993 Jun;80(6):788-93 [8330178.001]
  • [Cites] Br J Surg. 1993 Nov;80(11):1401-4 [8252348.001]
  • [Cites] Helv Chir Acta. 1994 Apr;60(4):599-604 [8034540.001]
  • [Cites] Surg Endosc. 1995 Oct;9(10):1106-12 [8553213.001]
  • [Cites] Harefuah. 1995 Oct;129(7-8):236-7, 295 [8549959.001]
  • [Cites] Br J Surg. 1996 Feb;83(2):207-10 [8689164.001]
  • [Cites] Langenbecks Arch Surg. 1998 Oct;383(5):320-4 [9860223.001]
  • [Cites] Colorectal Dis. 2005 Jan;7(1):47-50 [15606584.001]
  • [Cites] Colorectal Dis. 2005 Mar;7(2):133-7 [15720349.001]
  • [Cites] Chirurg. 2005 Apr;76(4):379-84 [15502890.001]
  • [Cites] Dig Surg. 2005;22(3):182-9; discussion 189-90 [16137996.001]
  • [Cites] Dis Colon Rectum. 2006 Feb;49(2):228-32 [16322965.001]
  • [Cites] Dig Liver Dis. 2006 Mar;38(3):202-7 [16461025.001]
  • [Cites] Ann Surg Oncol. 2006 Apr;13(4):547-56 [16514476.001]
  • [Cites] Colorectal Dis. 2006 Sep;8(7):581-5 [16919110.001]
  • [Cites] Colorectal Dis. 2006 Nov;8(9):795-9 [17032328.001]
  • [Cites] Tech Coloproctol. 2006 Dec;10(4):277-81 [17115311.001]
  • [Cites] Br J Surg. 2007 May;94(5):627-33 [17335125.001]
  • [Cites] Am J Surg. 2007 Nov;194(5):694-8 [17936438.001]
  • [Cites] Ann Surg. 2002 Mar;235(3):355-62 [11882757.001]
  • (PMID = 19701964.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] China
  • [Number-of-references] 41
  • [Other-IDs] NLM/ PMC2731246
  •  go-up   go-down


49. Oh SY, Park DI, Yoo TW, Kang MS, Kim SH, Park JH, Kim HJ, Cho YK, Sohn CI, Jeon WK, Kim BI, Son BH, Yoo CH: [Is gastric cancer a new indication for surveillance colonoscopy? Colon cancer is increased in gastric cancer patients]. Korean J Gastroenterol; 2006 Mar;47(3):191-7
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND/AIMS: It has been reported that the risk of gastric polyp is increased in various colonic polyposis syndromes or in series of patients with sporadic colonic polyps.
  • RESULTS: In the patient group, adenomatous polyps were diagnosed in 24/105 patients (22.9%) and colorectal adenocarcinoma in 10/105 patients (9.5%).
  • In the control group, adenomatous polyps were diagnosed in 78/269 patients (29.0%) and colorectal adenocarcinoma in 2/269 patients (0.7%).
  • [MeSH-minor] Adenomatous Polyps / diagnosis. Colonic Polyps / diagnosis. Female. Humans. Male. Middle Aged

  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16554672.001).
  • [ISSN] 1598-9992
  • [Journal-full-title] The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
  • [ISO-abbreviation] Korean J Gastroenterol
  • [Language] kor
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Korea (South)
  •  go-up   go-down


50. Hao CY, Moore DH, Wong P, Bennington JL, Lee NM, Chen LC: Alteration of gene expression in macroscopically normal colonic mucosa from individuals with a family history of sporadic colon cancer. Clin Cancer Res; 2005 Feb 15;11(4):1400-7
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • To determine whether these alterations also occur in the MNCM of individuals who have not developed colon cancer but are at high risk of doing so, we measured gene expression in the MNCM of individuals with a family history of colon cancer.
  • CONCLUSIONS: Molecular abnormalities that precede the appearance of adenomatous polyp are present in the MNCM of individuals who have a family history of colon cancer.
  • To assess this possibility, prospective studies will be needed to determine whether or not altered gene expression is associated with the subsequent development of adenomatous polyps and/ or colonic carcinomas.

  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15746039.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Interleukin-8; 0 / Membrane Proteins; 0 / PPAR delta; 0 / PPAR gamma; 0 / Serum Amyloid A Protein; 63231-63-0 / RNA; EC 1.14.99.1 / Cyclooxygenase 2; EC 1.14.99.1 / PTGS2 protein, human; EC 1.14.99.1 / Prostaglandin-Endoperoxide Synthases
  •  go-up   go-down


51. Benedix F, Köckerling F, Lippert H, Scheidbach H: Laparoscopic resection for endoscopically unresectable colorectal polyps: analysis of 525 patients. Surg Endosc; 2008 Dec;22(12):2576-82
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laparoscopic resection for endoscopically unresectable colorectal polyps: analysis of 525 patients.
  • BACKGROUND: For the management of endoscopically irretrievable polyps, several minimally invasive procedures are currently available as alternatives to conventional laparotomy.
  • METHODS: Within the framework of a prospective multicenter observational study, all patients with adenomatous polyps unsuitable for endoscopic removal and with benign histology were investigated.
  • In addition to an analysis of the perioperative course and the definitive histology, the overall and disease-free survival rates of patients with malignant transformation of colorectal adenomas were also calculated.
  • The perioperative morbidity rate was 20.8%, and malignant transformation occurred in a total of 18.1% of the adenomatous polyps.
  • Estimated 5-year overall and disease-free survival rates were 92.4% and 80.6%, respectively.
  • CONCLUSIONS: For the management of endoscopically unresectable polyps, laparoscopic resection is currently the technique of choice.
  • In the elderly patient presenting with comorbidities limited resection aiming to minimize surgical trauma in potentially benign disease may be considered.
  • [MeSH-major] Adenocarcinoma / surgery. Adenomatous Polyps / surgery. Colonic Polyps / surgery. Colorectal Neoplasms / surgery. Laparoscopy / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Colectomy / methods. Colonoscopy. Disease Progression. Disease-Free Survival. Female. Humans. Laparotomy / statistics & numerical data. Lymph Node Excision. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Invasiveness. Postoperative Complications / epidemiology. Prospective Studies. Young Adult

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Dis Colon Rectum. 2003 Mar;46(3):340-8 [12626909.001]
  • [Cites] N Engl J Med. 2004 May 13;350(20):2050-9 [15141043.001]
  • [Cites] Tech Coloproctol. 2006 Dec;10(4):303-7 [17115319.001]
  • [Cites] Surg Endosc. 1998 Nov;12(11):1341-4 [9788858.001]
  • [Cites] Surg Endosc. 2005 May;19(5):643-9 [15789256.001]
  • [Cites] JSLS. 2005 Jan-Mar;9(1):58-62 [15791972.001]
  • [Cites] Dis Colon Rectum. 2000 Sep;43(9):1246-9 [11005491.001]
  • [Cites] Lancet. 2002 Jun 29;359(9325):2224-9 [12103285.001]
  • [Cites] Dis Colon Rectum. 2001 May;44(5):746-8 [11357040.001]
  • [Cites] Surg Endosc. 1996 Jan;10(1):15-8 [8711597.001]
  • [Cites] Surg Endosc. 1997 Mar;11(3):264-7 [9079606.001]
  • [Cites] Dis Colon Rectum. 2006 Jun;49(6):879-82 [16598402.001]
  • [Cites] Mayo Clin Proc. 2000 Apr;75(4):344-8 [10761487.001]
  • [Cites] Surg Endosc. 2005 Sep;19(9):1252-5 [16132333.001]
  • [Cites] Surg Endosc. 2006 Jan;20(1):30-4 [16333547.001]
  • [Cites] Surg Endosc. 2007 Mar;21(3):400-3 [17180271.001]
  • [Cites] Int J Colorectal Dis. 1997;12(5):267-71 [9401839.001]
  • [Cites] Br J Surg. 1999 Apr;86(4):505-8 [10215825.001]
  • [Cites] Arch Surg. 2007 Mar;142(3):298-303 [17372057.001]
  • [Cites] Surg Endosc. 2008 Feb;22(2):506-9 [17704872.001]
  • [Cites] ANZ J Surg. 2003 Dec;73(12):988-95 [14632888.001]
  • (PMID = 18626704.001).
  • [ISSN] 1432-2218
  • [Journal-full-title] Surgical endoscopy
  • [ISO-abbreviation] Surg Endosc
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] Germany
  •  go-up   go-down


52. Galimov OV, Rylova TV, Khanov VO: [Endoscopy in the diagnosis and treatment of gastric polyps]. Vestn Khir Im I I Grek; 2008;167(5):65-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Endoscopy in the diagnosis and treatment of gastric polyps].
  • The authors present a clinico-statistical analysis of results of endoscopic polypectomy and dynamic observation of 258 patients with gastric polyps.
  • The aim of the investigation was to determine a true histological diagnosis of gastric polyps using excisional biopsy.
  • An endoscopic investigation has revealed 475 polyps in the stomach of 258 patients.
  • Endoscopic polypectomy by the method of electroexcision and preliminary submucous administration of solutions was used for 218 polyps having the size more than 0.5 cm.
  • Patients with formations located submucously and malignant tumors of the stomach (polypoid cancers included) were not investigated.
  • Metaplastic and dysplastic alterations characteristic of adenomatous polyps were detected by the method of chromoscopy.
  • [MeSH-major] Gastroscopy / methods. Polyps / pathology. Polyps / surgery. Stomach Diseases / pathology. Stomach Diseases / surgery

  • MedlinePlus Health Information. consumer health - Stomach Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19069827.001).
  • [ISSN] 0042-4625
  • [Journal-full-title] Vestnik khirurgii imeni I. I. Grekova
  • [ISO-abbreviation] Vestn. Khir. Im. I. I. Grek.
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
  •  go-up   go-down


53. Saul C, Prolla JC, Silva VD, Teixeira CR, Parada AA: Morphometric digital measurement of the luminal opening area of colonic crypts (pits) can differentiate the adenomas from other colonic lesions. Arq Gastroenterol; 2009 Apr-Jun;46(2):107-10
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CONTEXT: Differential diagnosis of hyperplastic vs adenomatous lesions is of crucial importance on the daily practice of colonoscopy.
  • Specific digital morphometry was used, to measure the diameter and area of the pits from hyperplastic lesions, adenomatous and carcinomatous lesions, always comparing them with the normal mucosa surrounding pits.
  • CONCLUSIONS: The morphometric characteristics of colonoscopy images allowing the observer to compare differences between hyperplastic and adenomatous polyps and colorectal carcinoma lesions.
  • Morphometric analysis is more an instance of decision to the colonoscopist and it has important value not for being subjective, but for being objective, since it generates digits of its measures.
  • The endoscopic removal of adenomatous polyps (polypectomy), or a more detailed study of the neoplastic lesions for helping the decision if endoscopic removal (mucosectomy) or surgical resection, and a conservative position in hyperplastic lesions, are proceedings that morphometrics, with another parameters, can help to decide.
  • [MeSH-major] Adenoma / pathology. Colonic Neoplasms / pathology. Colonic Polyps / pathology. Colonoscopy / methods. Image Processing, Computer-Assisted

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19578610.001).
  • [ISSN] 1678-4219
  • [Journal-full-title] Arquivos de gastroenterologia
  • [ISO-abbreviation] Arq Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
  •  go-up   go-down


54. McLaren CE, Fujikawa-Brooks S, Chen WP, Gillen DL, Pelot D, Gerner EW, Meyskens FL Jr: Longitudinal assessment of air conduction audiograms in a phase III clinical trial of difluoromethylornithine and sulindac for prevention of sporadic colorectal adenomas. Cancer Prev Res (Phila); 2008 Dec;1(7):514-21
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A phase III clinical trial assessed the recurrence of adenomatous polyps after treatment for 36 months with difluoromethylornithine (DFMO) plus sulindac or matched placebos.
  • Dose intensity did not add information to models.

  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. Eflornithine .
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Otolaryngol Clin North Am. 1993 Oct;26(5):759-89 [8233488.001]
  • [Cites] Cancer Prev Res (Phila). 2008 Jun;1(1):32-8 [18841250.001]
  • [Cites] N Engl J Med. 1993 Dec 30;329(27):1977-81 [8247072.001]
  • [Cites] Scand Audiol. 1994;23(1):13-37 [8184280.001]
  • [Cites] J Acoust Soc Am. 1996 Oct;100(4 Pt 1):1949-67 [8865630.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 1997 Dec;123(12):1281-6 [9413354.001]
  • [Cites] Eur Arch Otorhinolaryngol. 1997;254(9-10):422-4 [9438110.001]
  • [Cites] Otolaryngol Clin North Am. 1993 Oct;26(5):903-14 [8233496.001]
  • [Cites] Stat Med. 2000 May 30;19(10):1265-75 [10814976.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2000 Nov;9(11):1155-62 [11097222.001]
  • [Cites] J Clin Oncol. 2001 Mar 15;19(6):1658-63 [11250994.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 2001 May;127(5):553-8 [11346432.001]
  • [Cites] Ear Hear. 2001 Jun;22(3):200-11 [11409856.001]
  • [Cites] Brain. 2002 Mar;125(Pt 3):524-37 [11872610.001]
  • [Cites] Hear Res. 2002 Apr;166(1-2):192-201 [12062771.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2004 Jul;13(7):1250-2 [15247138.001]
  • [Cites] Cancer Treat Rep. 1986 Jul;70(7):843-5 [3013400.001]
  • [Cites] J Natl Cancer Inst. 1986 Dec;77(6):1309-13 [3099048.001]
  • [Cites] Invest New Drugs. 1986;4(3):257-62 [3102397.001]
  • [Cites] J Biol Response Mod. 1988 Aug;7(4):409-15 [3139843.001]
  • [Cites] Biometrics. 1988 Dec;44(4):1049-60 [3233245.001]
  • [Cites] Am J Clin Oncol. 1991 Aug;14(4):331-5 [1862765.001]
  • [Cites] Clin Cancer Res. 1999 May;5(5):945-51 [10353725.001]
  • [Cites] AMA Arch Otolaryngol. 1959 Feb;69(2):200-11 [13616814.001]
  • [Cites] Ear Hear. 2005 Jun;26(3):290-8 [15937410.001]
  • [Cites] Arch Pediatr Adolesc Med. 2005 Dec;159(12):1151-6 [16330739.001]
  • [Cites] Amino Acids. 2007 Aug;33(2):189-95 [17396214.001]
  • [Cites] Natl Vital Stat Rep. 2007 Aug 21;55(19):1-119 [17867520.001]
  • [Cites] Ear Hear. 2008 Jan;29(1):121-33 [18091096.001]
  • [CommentIn] Cancer Prev Res (Phila). 2008 Dec;1(7):499-502 [19138998.001]
  • (PMID = 19139001.001).
  • [ISSN] 1940-6215
  • [Journal-full-title] Cancer prevention research (Philadelphia, Pa.)
  • [ISO-abbreviation] Cancer Prev Res (Phila)
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / R01 CA059024; United States / NCI NIH HHS / CA / R01 CA088078-05; United States / NCI NIH HHS / CA / P30 CA023074; None / None / / R01 CA059024-04; United States / NCI NIH HHS / CA / P30 CA062203-13; United States / NCI NIH HHS / CA / R01 CA059024-04; United States / NCI NIH HHS / CA / CA 23074; United States / NCI NIH HHS / CN / N01 CN 75019; United States / NCI NIH HHS / CA / CA 95060; United States / NCI NIH HHS / CN / N01 CN075019; United States / NCI NIH HHS / CA / P50 CA095060-07; United States / NCI NIH HHS / CA / CA 88078; United States / NCI NIH HHS / CA / P50 CA095060; United States / NCI NIH HHS / CA / CA 59024; United States / NCI NIH HHS / CA / CA095060-07; United States / NCI NIH HHS / CA / P30 CA062203; United States / NCI NIH HHS / CA / R01 CA088078; United States / NCI NIH HHS / CN / N01 CN085182; United States / NCI NIH HHS / CA / CA088078-05; United States / NCI NIH HHS / CA / R01 CA063640; United States / NCI NIH HHS / CA / CA062203-13
  • [Publication-type] Clinical Trial, Phase III; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 184SNS8VUH / Sulindac; ZQN1G5V6SR / Eflornithine
  • [Other-IDs] NLM/ NIHMS91693; NLM/ PMC2702261
  •  go-up   go-down


55. Pérez R, Lasa A, Toro DH, Cruz-Correa M, Martinez-Souss J: Relationship between sporadic hyperplastic polyps and colorectal neoplasia in Hispanic veterans. P R Health Sci J; 2010 Dec;29(4):372-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Relationship between sporadic hyperplastic polyps and colorectal neoplasia in Hispanic veterans.
  • OBJECTIVE: Hyperplastic polyps (HP) traditionally have been regarded as having no malignant potential.
  • Some studies have suggested that HP in the distal colon may predict presence of adenomatous polyps in the proximal colon.
  • METHODS: The study consisted of a retrospective review of all the medical records of patients who underwent a colonoscopy for the first time during the calendar year 2005 and had a pathologic diagnosis of HP, tubular adenoma (TA), tubulovillous adenoma (TVA), villous adenoma (VA) and/or colon adenocarcinoma at the VA Caribbean Healthcare System.
  • CONCLUSION: The present study suggests that the presence of HP is not associated with CRN in our veteran population.
  • The results of this study support current colon cancer guidelines in which surveillance for HP is not recommended.
  • [MeSH-major] Colonic Polyps / pathology. Colorectal Neoplasms / pathology. Hispanic Americans


56. Pranesh N, Haboubi NY, O'Dwyer ST: Pigmented mesenteric lymphadenopathy in familial adenomatous polyposis - an unusual cause of intraoperative abandonment of ileo-anal pouch. Ann R Coll Surg Engl; 2005 Jul;87(4):W1-4
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pigmented mesenteric lymphadenopathy in familial adenomatous polyposis - an unusual cause of intraoperative abandonment of ileo-anal pouch.
  • Familial adenomatous polyposis (FAP) is an autosomal dominant condition with near complete penetrance, characterised by the presence of numerous adenomatous polyps of the colon and rectum.
  • [MeSH-major] Adenomatous Polyposis Coli / surgery. Lymphatic Diseases / complications. Melanosis / complications. Mesentery. Peritoneal Diseases / complications


57. Hartmann D, Bassler B, Schilling D, Adamek HE, Jakobs R, Pfeifer B, Eickhoff A, Zindel C, Riemann JF, Layer G: Colorectal polyps: detection with dark-lumen MR colonography versus conventional colonoscopy. Radiology; 2006 Jan;238(1):143-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Colorectal polyps: detection with dark-lumen MR colonography versus conventional colonoscopy.
  • PURPOSE: To prospectively compare dark-lumen magnetic resonance (MR) colonography with conventional colonoscopy in the detection of colorectal polyps.
  • Results of MR colonography were analyzed on a per-polyp and per-patient basis.
  • In the other 49 patients (53%), conventional colonoscopy depicted 107 polyps (82 adenomas, 25 hyperplastic polyps) and seven carcinomas.
  • At per-polyp analysis, sensitivity of MR colonography in the detection of adenomatous polyps was 100% for polyps at least 10 mm in diameter and 84.2% for polyps 6-9 mm in diameter.
  • At per-patient analysis, the accuracy of MR colonography was 93.1% (sensitivity, 89%; specificity, 96%) if detection of adenomatous polyps of all sizes was considered.
  • CONCLUSION: Dark-lumen MR colonography is a promising modality with high accuracy for detecting colorectal polyps larger than 5 mm in diameter.
  • [MeSH-major] Colonic Polyps / diagnosis. Colonoscopy. Magnetic Resonance Imaging / methods

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • MedlinePlus Health Information. consumer health - MRI Scans.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] RSNA, 2005.
  • (PMID = 16304088.001).
  • [ISSN] 0033-8419
  • [Journal-full-title] Radiology
  • [ISO-abbreviation] Radiology
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Organometallic Compounds; 15G12L5X8K / gadobenic acid; 6HG8UB2MUY / Meglumine
  •  go-up   go-down


58. Döbrôssy L, Kovács A, Budai A, Cornides A, Ottó S, Tulassay Z: [The state of the colorectal screening in Hungary: lessons of the pilot programs]. Orv Hetil; 2007 Sep 23;148(38):1787-93
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In Hungary, colorectal cancer is the second most common malignant disease.
  • The compliance was not more than 30-45%.
  • The programmes revealed a great number of adenomatous polyps and early cancers, and in the way, the effectiveness of the method has been proved.


59. Simmen FA, Frank JA, Wu X, Xiao R, Hennings LJ, Prior RL: Lack of efficacy of blueberry in nutritional prevention of azoxymethane-initiated cancers of rat small intestine and colon. BMC Gastroenterol; 2009 Sep 16;9:67
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BB increased (P < 0.05) ACF numbers within the distal colon of female but not male rats.
  • There was a tendency (0.1 > P > 0.05) for fewer adenocarcinomas (relative to total of adenomatous polyps plus adenocarcinomas) in colons of female than male tumor-bearing rats; in small intestine, this gender difference was significant (P < 0.05).
  • BB favored (P < 0.05) fewer adenocarcinomas and more adenomatous polyps (as a proportion of total tumor number) in female rat small intestine.
  • CONCLUSION: Results did not indicate robust cancer-preventive effects of BB.
  • Data indicate the potential for slowing tumor progression (adenomatous polyp to adenocarcinoma) by BB.

  • MedlinePlus Health Information. consumer health - Intestinal Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] World J Gastroenterol. 2002 Oct;8(5):847-52 [12378628.001]
  • [Cites] Carcinogenesis. 2001 Nov;22(11):1831-5 [11698346.001]
  • [Cites] Cancer Lett. 2003 May 8;194(1):13-9 [12706854.001]
  • [Cites] Am J Clin Nutr. 2004 Feb;79(2):274-81 [14749234.001]
  • [Cites] Cancer Causes Control. 2003 Dec;14(10):959-70 [14750535.001]
  • [Cites] Nutr Cancer. 2004;49(2):131-8 [15489205.001]
  • [Cites] Digestion. 1976;14(4):311-8 [964470.001]
  • [Cites] Cancer. 1977 Nov;40(5 Suppl):2436-45 [200341.001]
  • [Cites] J Agric Food Chem. 2006 Dec 13;54(25):9322-8 [17147414.001]
  • [Cites] J Agric Food Chem. 2006 Dec 13;54(25):9329-39 [17147415.001]
  • [Cites] Clin Cancer Res. 2007 Jan 1;13(1):350-5 [17200374.001]
  • [Cites] Food Chem Toxicol. 2007 May;45(5):725-32 [17321025.001]
  • [Cites] Comp Med. 2002 Feb;52(1):50-7 [11900413.001]
  • [Cites] Nutr Cancer. 2001;40(2):125-33 [11962247.001]
  • [Cites] Nutr Cancer. 2001;41(1-2):145-9 [12094617.001]
  • [Cites] Carcinogenesis. 1996 Jan;17(1):95-8 [8565143.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 1996 Dec;5(12):1013-5 [8959325.001]
  • [Cites] Cancer Lett. 1998 Aug 14;130(1-2):29-34 [9751253.001]
  • [Cites] Br J Cancer. 1999 Mar;79(7-8):1283-7 [10098773.001]
  • [Cites] Int J Cancer. 1999 Jul 19;82(2):171-4 [10389747.001]
  • [Cites] Bull World Health Organ. 2005 Feb;83(2):100-8 [15744402.001]
  • [Cites] Cancer Causes Control. 2005 Apr;16(3):225-33 [15947874.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2005 Jul;14(7):1619-25 [16030092.001]
  • [Cites] J Agric Food Chem. 2005 Sep 7;53(18):7320-9 [16131149.001]
  • [Cites] Cancer Res. 2006 Apr 1;66(7):3942-53 [16585224.001]
  • [Cites] Mol Nutr Food Res. 2006 Apr;50(4-5):418-23 [16548015.001]
  • [Cites] J Nutr Biochem. 2006 Sep;17(9):626-34 [16504496.001]
  • [Cites] Int J Cancer. 2006 Nov 1;119(9):2213-20 [16823841.001]
  • [Cites] Free Radic Res. 2006 Oct;40(10):1014-28 [17015246.001]
  • [Cites] J Agric Food Chem. 2007 Apr 18;55(8):3180-5 [17381106.001]
  • [Cites] J Am Coll Nutr. 2007 Apr;26(2):170-81 [17536129.001]
  • [Cites] Clin Gastroenterol Hepatol. 2007 Jun;5(6):736-42 [17544999.001]
  • [Cites] Am J Epidemiol. 2007 Jul 15;166(2):170-80 [17485731.001]
  • [Cites] Semin Cancer Biol. 2007 Oct;17(5):403-10 [17574861.001]
  • [Cites] J Agric Food Chem. 2007 Sep 19;55(19):7777-85 [17696482.001]
  • [Cites] J Nutr. 2007 Oct;137(10):2285-90 [17885012.001]
  • [Cites] J Natl Cancer Inst. 2007 Oct 3;99(19):1471-83 [17895473.001]
  • [Cites] J Endocrinol. 2007 Oct;195(1):79-87 [17911399.001]
  • [Cites] Am J Clin Nutr. 2007 Dec;86(6):1754-64 [18065596.001]
  • [Cites] CA Cancer J Clin. 2008 Mar-Apr;58(2):71-96 [18287387.001]
  • [Cites] Am J Physiol Gastrointest Liver Physiol. 2008 Apr;294(4):G868-76 [18239060.001]
  • [Cites] Arch Physiol Biochem. 2008 Feb;114(1):63-70 [18465360.001]
  • [Cites] Am J Clin Nutr. 2008 Sep;88(3):730-7 [18779290.001]
  • [Cites] Am J Epidemiol. 2000 Dec 1;152(11):1081-92 [11117618.001]
  • [Cites] J Natl Cancer Inst. 2001 Apr 4;93(7):525-33 [11287446.001]
  • [Cites] Nutr Cancer. 2002;43(1):1-21 [12467130.001]
  • (PMID = 19758446.001).
  • [ISSN] 1471-230X
  • [Journal-full-title] BMC gastroenterology
  • [ISO-abbreviation] BMC Gastroenterol
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CB / N02-CB-07008
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 0 / C-Peptide; MO0N1J0SEN / Azoxymethane
  • [Other-IDs] NLM/ PMC2752457
  •  go-up   go-down


60. Kaczka A, Kumor A, Pietruczuk M, Małecka-Panas E: [Serum concentration of insulin, C-peptide and insulin-like growth factor I in patients with colon adenomas and colorectal cancer]. Pol Merkur Lekarski; 2007 May;22(131):373-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In patients with colon adenomatous polyps we also observed higher serum IGF-I concentrations I comparing to the control group (82.1 ng/ml vs. 60.96 ng/ml), in high dysplasia adenomas (84.12 ng/ml vs. 79.67 ng/ml) and in smaller adenomas to 1 cm diameter (97.98 ng/ml vs. 73.28 ng/ml), but the differences were not significant.
  • We also observed higher concentration of C-peptide in patients with low grade dysplasia adenomas (665.24 pmol/l vs. 498.13 pmol/l) and with small polyps (611.51 pmol/l vs. 514.89 pmol/l).
  • [MeSH-major] Adenoma / blood. Adenomatous Polyps / blood. C-Peptide / blood. Colonic Polyps / blood. Colorectal Neoplasms / blood. Insulin / blood

  • Genetic Alliance. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Diabetes Medicines.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17679371.001).
  • [ISSN] 1426-9686
  • [Journal-full-title] Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego
  • [ISO-abbreviation] Pol. Merkur. Lekarski
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / C-Peptide; 0 / Insulin; 67763-96-6 / Insulin-Like Growth Factor I
  •  go-up   go-down


61. Sato Y, Nozaki R, Yamada K, Takano M, Haruma K: Relation between obesity and adenomatous polyps of the large bowel. Dig Endosc; 2009 Jul;21(3):154-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Relation between obesity and adenomatous polyps of the large bowel.
  • BACKGROUND: We compared the prevalence of colorectal adenoma (polyps) in men and women and examined the role of body mass index (BMI) on polyp risk according to patient age and gender.
  • METHODS: The risk of developing colorectal polyps was studied in 15 380 subjects (7155 men and 8225 women) who underwent colonoscopy for the first time from April 1998 to March 2006 at our 'Human Dry Dock', which is the check-up service provided in Japan.
  • Eligible subjects were 20-86 years old (mean age +/- SD, 47.3 +/- 8.5) and were free of invasive cancer, hyperplastic polyps and familial polyposis.
  • Polyps were found in 1590 subjects (1062 men and 528 women).
  • The odds ratio (OR) of detection of polyps in relation to obesity was determined in all cases by multivariate logistic regression analysis after making an adjustment for gender and age.
  • RESULTS: The OR of polyp detection in obese subjects (BMI >or= 25) versus non-obese subjects (BMI < 25, OR = 1) was 1.34 (P < 0.001) in men and 1.13 (P = 0.26) in women.
  • CONCLUSIONS: We conclude that obesity in men is a risk factor for the development of polyps.
  • [MeSH-major] Adenomatous Polyps / epidemiology. Colonic Neoplasms / epidemiology. Colonic Polyps / epidemiology

  • Genetic Alliance. consumer health - Obesity.
  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19691761.001).
  • [ISSN] 1443-1661
  • [Journal-full-title] Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society
  • [ISO-abbreviation] Dig Endosc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
  •  go-up   go-down


62. Keku TO, Lund PK, Galanko J, Simmons JG, Woosley JT, Sandler RS: Insulin resistance, apoptosis, and colorectal adenoma risk. Cancer Epidemiol Biomarkers Prev; 2005 Sep;14(9):2076-81
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Insulin resistance, apoptosis, and colorectal adenoma risk.
  • However, the role of insulin and markers of glucose control in the development of adenomas, precursors to colorectal cancer, has not been fully explored.
  • Participants were classified as cases or controls based on whether they had one or more colorectal adenomatous polyps.
  • Logistic regression was used to examine the association between adenoma status and insulin-IGF markers.
  • Adenoma cases (n = 239) and adenoma-free controls (n = 517) provided rectal biopsies and/or blood samples and interview data.
  • Those in the highest quartile of insulin (adjusted odds ratio, 2.2; 95% confidence interval, 1.1-4.2) and glucose (adjusted odds ratio, 1.8; 95% confidence interval, 0.9-3.6) were more likely to have an adenoma compared with the lowest quartile.
  • The results provide novel evidence that elevated insulin and glucose are associated with increased adenoma risk and decreased apoptosis in normal rectal mucosa.
  • These findings suggest that insulin may act early in the adenoma-carcinoma sequence to promote the development of colorectal adenoma by decreasing apoptosis in the normal mucosa.
  • [MeSH-minor] Adenoma / epidemiology. Adenoma / etiology. Adenoma / physiopathology. Blood Glucose / analysis. Case-Control Studies. Cell Transformation, Neoplastic. Diet. Female. Humans. Life Style. Male. Middle Aged. Risk Assessment. Somatomedins / analysis

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Diabetes Medicines.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16172212.001).
  • [ISSN] 1055-9965
  • [Journal-full-title] Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
  • [ISO-abbreviation] Cancer Epidemiol. Biomarkers Prev.
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / P30 DK34987; United States / NCI NIH HHS / CA / R01 CA 44684; United States / NCI NIH HHS / CA / R01 CA93654-01
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Blood Glucose; 0 / Insulin; 0 / Somatomedins
  •  go-up   go-down


63. Ozsunar Y, Coskun G, Delibaş N, Uz B, Yükselen V: Diagnostic accuracy and tolerability of contrast enhanced CT colonoscopy in symptomatic patients with increased risk for colorectal cancer. Eur J Radiol; 2009 Sep;71(3):513-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Two masses and eight polyps, consisted of 1 tubulovillous, 1 tubular, 2 villous adenoma, 4 adenomatous polyp, 4 adenocarcinoma, were identified.

  • Genetic Alliance. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18597964.001).
  • [ISSN] 1872-7727
  • [Journal-full-title] European journal of radiology
  • [ISO-abbreviation] Eur J Radiol
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Contrast Media
  •  go-up   go-down


64. Rennert G, Almog R, Tomsho LP, Low M, Pinchev M, Chaiter Y, Bonner JD, Rennert HS, Greenson JK, Gruber SB: Colorectal polyps in carriers of the APC I1307K polymorphism. Dis Colon Rectum; 2005 Dec;48(12):2317-21
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Colorectal polyps in carriers of the APC I1307K polymorphism.
  • However, it is not known if endoscopic surveillance of this high-risk group is warranted.
  • The prevalence of polyps and adenomas in specimens of colorectal cancer who are carriers and noncarriers of the APC I1307K polymorphism is compared.
  • METHOD: Prevalence of adenomatous polyps in the pathology specimens of the study participants, stratified by their APC I1307K polymorphism status, was studied in 900 consecutive cases of colorectal cancer diagnosed in northern Israel between 1998 and 2002, within the framework of a population-based, case-controlled study (MECC Study).
  • After adjustment for age, APC I1307K carriers were significantly more likely than noncarriers to have polyps in their surgical specimen (51.3 percent vs. 32.6 percent, P = 0.002).
  • Adenomas with a tubular component (either tubular adenomas or tubulovillous adenomas), but not villous adenomas, were significantly more frequent among carriers (37.2 percent vs. 23.6 percent, P = 0.005).
  • [MeSH-major] Adenoma / genetics. Colonic Polyps / genetics. Colorectal Neoplasms / genetics. Genes, APC. Polymorphism, Genetic

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16228836.001).
  • [ISSN] 0012-3706
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


65. Kalafatis P, Zougkas K: Adenomatous polyp of the verumontanum accompanied by parabulbous epidermoid cyst and cryptorchidism in an adult male. Urol Int; 2006;77(2):187-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatous polyp of the verumontanum accompanied by parabulbous epidermoid cyst and cryptorchidism in an adult male.
  • The coexistence of polyp of the verumontanum, epidermoid paraurethral cyst and cryptorchidism presents a mosaic of congenital anomalies of the urogenital tract.
  • Transurethral resection of the urethral polyp with a simultaneous excision of the cystic formation via a perineal approach followed by a left-sided funiculolysis and orchiopexy were performed.
  • [MeSH-major] Adenomatous Polyps / complications. Cryptorchidism / complications. Epidermal Cyst / complications. Urethral Diseases / complications. Urethral Neoplasms / complications

  • MedlinePlus Health Information. consumer health - Urethral Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16888430.001).
  • [ISSN] 0042-1138
  • [Journal-full-title] Urologia internationalis
  • [ISO-abbreviation] Urol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
  •  go-up   go-down


66. Kim BJ, Kim JY, Chang DK, Son HJ, Rhee PL, Kim JJ, Rhee JC, Choe YH, Choi YH, Shim SG, Kim YH: Coexistence between carotid artery stenosis and colorectal adenomatous polyps in middle-aged men. Digestion; 2010;81(1):20-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Coexistence between carotid artery stenosis and colorectal adenomatous polyps in middle-aged men.
  • BACKGROUND: Colorectal neoplasia and cardiovascular disease appear to share common risk factors.
  • RESULTS: The prevalence of overall colorectal adenomatous polyps (APs) was 31.4% (591/1,877).
  • [MeSH-major] Adenomatous Polyps / complications. Carotid Stenosis / complications. Colorectal Neoplasms / complications

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2009 S. Karger AG, Basel.
  • [CommentIn] Digestion. 2010;81(1):18-9 [20029205.001]
  • [CommentIn] Digestion. 2010;81(1):16-7 [20029204.001]
  • (PMID = 20051688.001).
  • [ISSN] 1421-9867
  • [Journal-full-title] Digestion
  • [ISO-abbreviation] Digestion
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  •  go-up   go-down


67. Park SY, Kim BC, Shin SJ, Lee SK, Kim TI, Kim WH: Proximal shift in the distribution of adenomatous polyps in Korea over the past ten years. Hepatogastroenterology; 2009 May-Jun;56(91-92):677-81
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Proximal shift in the distribution of adenomatous polyps in Korea over the past ten years.
  • BACKGROUND/AIMS: Several reports have suggested a trend of right-side shift of colorectal cancer; however, there were only a few studies on the chronologic changes in the distribution of adenomatous polyps.
  • We aimed to study the changes in the distribution of colorectal adenomatous polyps over the past ten years.
  • Patients who had an adenomatous polyp with a diameter of at least 5mm were included.
  • Of these, patients with a history of colon resection, colorectal cancer, colorectal polyp, inflammatory bowel disease, HNPCC, or familial adenomatous polyposis were excluded.
  • RESULTS: A total of 2,498 patients and 4,591 adenomatous polyps were included in this study.
  • Analysis with respect to number of patients showed significant increases in the proportion of patients with adenomatous polyp on the proximal colon, from 48.5% to 66.3% (p<0.001).
  • Analysis with respect to number of polyps revealed that the proportion of adenomatous polyps on the proximal colon significantly increased from 48.9% to 62.3% (p<0.001).
  • CONCLUSIONS: The proportion of adenomatous polyp on the proximal colon significantly increased over the past 10 years.
  • [MeSH-major] Adenomatous Polyposis Coli / ethnology. Adenomatous Polyposis Coli / pathology. Asian Continental Ancestry Group / statistics & numerical data

  • Genetic Alliance. consumer health - TEN.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19621679.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  •  go-up   go-down


68. Allison JE, Sakoda LC, Levin TR, Tucker JP, Tekawa IS, Cuff T, Pauly MP, Shlager L, Palitz AM, Zhao WK, Schwartz JS, Ransohoff DF, Selby JV: Screening for colorectal neoplasms with new fecal occult blood tests: update on performance characteristics. J Natl Cancer Inst; 2007 Oct 3;99(19):1462-70
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: One type of fecal occult blood test (FOBT), the unrehydrated guaiac fecal occult blood test (GT), is recommended by the United States Preventive Services Task Force and the Institute of Medicine for use in screening programs, but it has relatively low sensitivity as a single test for detecting advanced colonic neoplasms (cancer and adenomatous polyps > or = 1 cm in diameter).

  • MedlinePlus Health Information. consumer health - Bowel Movement.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. GUM GUAIAC .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] J Natl Cancer Inst. 2007 Oct 3;99(19):1424-5 [17895471.001]
  • (PMID = 17895475.001).
  • [ISSN] 1460-2105
  • [Journal-full-title] Journal of the National Cancer Institute
  • [ISO-abbreviation] J. Natl. Cancer Inst.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / 1R01CA074562-01
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Indicators and Reagents; 9000-29-7 / Guaiac
  •  go-up   go-down


69. Chen SC, Rex DK: Variable detection of nonadenomatous polyps by individual endoscopists at colonoscopy and correlation with adenoma detection. J Clin Gastroenterol; 2008 Jul;42(6):704-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Variable detection of nonadenomatous polyps by individual endoscopists at colonoscopy and correlation with adenoma detection.
  • AIM: To describe the removal rates of nonadenomas, variability between endoscopists, and the association of adenoma removal with nonadenoma removal.
  • Patients with inflammatory bowel disease, polyp syndromes, or who were referred for polypectomy were excluded.
  • The prevalence of nonadenomatous polyps increased from 26.6% at age 30 years to 29.3% at age 70 years (P=0.02); this association was much less powerful than that of age with removal of adenomas.
  • The range of finding > or =1 nonadenomatous polyp was 11.8% to 34.9%.
  • The correlation between adenoma detection and nonadenoma removal by individual endoscopists for the full cohort was 0.79 and for persons age > or =50 years was 0.84.
  • CONCLUSIONS: Detection of nonadenomatous polyps by individual endoscopists at colonoscopy is highly variable and correlates with increased removal rates of adenomatous polyps.
  • [MeSH-major] Adenomatous Polyps / diagnosis. Colonic Polyps / diagnosis. Colonoscopy / standards

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18496392.001).
  • [ISSN] 1539-2031
  • [Journal-full-title] Journal of clinical gastroenterology
  • [ISO-abbreviation] J. Clin. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


70. Yeruham I, Perl S, Lahav D: Anal adenomatous polyps in a crossbred beef cow. Vet Rec; 2005 Aug 13;157(7):204
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anal adenomatous polyps in a crossbred beef cow.
  • [MeSH-major] Adenomatous Polyps / veterinary. Anus Neoplasms / veterinary. Cattle Diseases / pathology

  • MedlinePlus Health Information. consumer health - Anal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16100372.001).
  • [ISSN] 0042-4900
  • [Journal-full-title] The Veterinary record
  • [ISO-abbreviation] Vet. Rec.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  •  go-up   go-down


71. Korstanje A, van Eeden S, Offerhaus JA, Waltman FL, Hartog Gd, Roelandse FW, Souverijn JH, Biemond I, Lamers CB: Comparison between serology and histology in the diagnosis of advanced gastric body atrophy: a study in a Dutch primary community. J Clin Gastroenterol; 2008 Jan;42(1):18-22
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Data on GBA in a primary health care community in the Netherlands have not been reported.
  • No adenomatous polyps, tumors, or dysplastic alterations were found.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Antibodies, Bacterial / blood. Atrophy / pathology. Autoantibodies / blood. Autoimmune Diseases / epidemiology. Biopsy. Chronic Disease. Cohort Studies. Diagnosis, Differential. Endoscopy. Female. Gastric Fundus / pathology. Gastrins / blood. Helicobacter Infections / epidemiology. Helicobacter pylori / immunology. Humans. Male. Middle Aged. Netherlands / epidemiology. Pepsinogens / blood. Prevalence. Pyloric Antrum / pathology. Serologic Tests

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18097284.001).
  • [ISSN] 0192-0790
  • [Journal-full-title] Journal of clinical gastroenterology
  • [ISO-abbreviation] J. Clin. Gastroenterol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Bacterial; 0 / Autoantibodies; 0 / Gastrins; 0 / Pepsinogens
  •  go-up   go-down


72. Romano G, Cocchiara G, Maniaci S, Buscemi G, Calderone F, Gioè FP, Romano M: [The role of colonoscopy in patient follow-up after surgery for colorectal cancer. A retrospective study and review of the literature]. G Chir; 2007 Oct;28(10):399-402
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • To improve survival rate after colon or rectum resection for cancer patients should be strictly followed up in order to identify possible local disease relapse or metachronous neoplasia.
  • In addition, in 11 cases, there were 3 right colon adenomatous polyps, 2 transverse colon polyps (one villous and the other tubular), 5 descending colon polyps (three tubular and two villous) and 1 tubulo-villous polyp of the rectum.
  • An examination of the data resulting from our own 68 cases shows that, in spite of the fact that no local disease relapse or metachronous neoplasia was observed, the identification of 11 polyps would suggest that the use of colonoscopy in such patients might be the gold standard for early diagnosis of recurrences and new polyps.
  • [MeSH-minor] Aged. Colonic Polyps / diagnosis. Female. Follow-Up Studies. Humans. Male. Middle Aged. Predictive Value of Tests. Retrospective Studies

  • Genetic Alliance. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17915057.001).
  • [ISSN] 0391-9005
  • [Journal-full-title] Il Giornale di chirurgia
  • [ISO-abbreviation] G Chir
  • [Language] ita
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 55
  •  go-up   go-down


73. Siddiqui AA, Patel A, Huerta S: Determinants of compliance with colonoscopy in patients with adenomatous colon polyps in a veteran population. Aliment Pharmacol Ther; 2006 Dec;24(11-12):1623-30
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Determinants of compliance with colonoscopy in patients with adenomatous colon polyps in a veteran population.
  • AIM: To determine factors affecting compliance of a follow-up colonoscopy in patients with previously diagnosed adenomatous colon polyps.
  • METHODS: A retrospective review was performed on patients with adenomatous polyps excised between January and December 1998.
  • RESULTS: One hundred and nineteen patients with adenomatous colon polyps were identified.
  • In a univariate analysis, greater number of polyps (P = 0.04), NSAID use (P = 0.02), statin use (P = 0.005), first-degree relatives with colon cancer (P = 0.05) and compliance with out-patient clinic follow-up (P < 0.001) were significantly associated with patient compliance.
  • [MeSH-major] Adenomatous Polyps / pathology. Colonic Neoplasms / pathology. Colonic Polyps / pathology. Colonoscopy. Patient Compliance

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17206950.001).
  • [ISSN] 0269-2813
  • [Journal-full-title] Alimentary pharmacology & therapeutics
  • [ISO-abbreviation] Aliment. Pharmacol. Ther.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  •  go-up   go-down


74. Martayan A, Sanchez-Mete L, Baldelli R, Falvo E, Barnabei A, Conti L, Giacomini P, Appetecchia M, Stigliano V: Gene variants associated to malignant thyroid disease in familial adenomatous polyposis: a novel APC germline mutation. J Endocrinol Invest; 2010 Oct;33(9):603-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gene variants associated to malignant thyroid disease in familial adenomatous polyposis: a novel APC germline mutation.
  • BACKGROUND AND AIM: Familial adenomatous polyposis (FAP) is an autosomal inherited syndrome characterized by hundreds to thousands colorectal adenomatous polyps with oncological transformation lifetime risk of 100%.
  • The aim of this study was to evaluate the frequency of PTC among our series of FAP patients and to assess the type of gene mutation associated with the disease.
  • RESULTS: In 13/54 (24.1%) subjects, an eumetabolic thyroid disease was found: plurinodular disease in 7/54 (13.0%); single nodule in 4/54 (7.4%); in 2/54 patients (3.7%), we found a malignant nodule characterized after total thyroidectomy as a classical PTC.
  • Both patients had classic FAP phenotype and genetic analysis revealed two pathogenetic APC mutations: c.3183_87delACAAA, a recurrent pathogenetic variant and del9-10 (del9080dup11), a novel, not previously described genomic rearrangement.
  • [MeSH-major] Adenomatous Polyposis Coli / genetics. Carcinoma, Papillary / genetics. Genes, APC. Germ-Line Mutation. Thyroid Neoplasms / genetics


75. Puppa G, Colombari R: Brown colon (melanosis coli) harbouring pale tumors (adenocarcinoma and an adenomatous polyp). J Gastrointestin Liver Dis; 2009 Dec;18(4):509-11
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Brown colon (melanosis coli) harbouring pale tumors (adenocarcinoma and an adenomatous polyp).
  • [MeSH-major] Adenocarcinoma / pathology. Adenomatous Polyps / pathology. Colonic Diseases / pathology. Colonic Neoplasms / pathology. Melanosis / pathology

  • MedlinePlus Health Information. consumer health - Colonic Diseases.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20076832.001).
  • [ISSN] 1841-8724
  • [Journal-full-title] Journal of gastrointestinal and liver diseases : JGLD
  • [ISO-abbreviation] J Gastrointestin Liver Dis
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Romania
  •  go-up   go-down


76. Manes G, Imbesi V, Ardizzone S, Cassinotti A, Bosani M, Massari A, Porro GB: Appropriateness and diagnostic yield of colonoscopy in the management of patients with ulcerative colitis: a prospective study in an open access endoscopy service. Inflamm Bowel Dis; 2008 Aug;14(8):1133-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Colonoscopy is frequently performed in ulcerative colitis (UC), but its benefit in the management of the disease is a matter of debate.
  • Endpoints for colonoscopy-improving management were prospectively defined: change in medical therapy, need for adjunctive procedures, identification or exclusion of cancer, adenomatous polyps, or other conditions with clinical impact.
  • In 46% of patients endoscopy revealed a significant lesion; this rate was higher for indicated (67.2) than for not indicated procedures (13.5%, P < 0.0001).
  • The endoscopist's decision was altered by the endoscopic finding in 7.6% of cases and was not different between appropriate and inappropriate procedures.
  • Relevant endoscopic findings have a relatively low impact on the medical treatment, but may have a very important value in the prognostic assessment of the disease.

  • Genetic Alliance. consumer health - Ulcerative Colitis.
  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • MedlinePlus Health Information. consumer health - Ulcerative Colitis.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18314901.001).
  • [ISSN] 1536-4844
  • [Journal-full-title] Inflammatory bowel diseases
  • [ISO-abbreviation] Inflamm. Bowel Dis.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


77. Yee J, Rosen MP, Blake MA, Baker ME, Cash BD, Fidler JL, Grant TH, Greene FL, Jones B, Katz DS, Lalani T, Miller FH, Small WC, Sudakoff GS, Warshauer DM: ACR Appropriateness Criteria on colorectal cancer screening. J Am Coll Radiol; 2010 Sep;7(9):670-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This malignancy is ideally suited for screening because the detection and removal of the precursor adenomatous polyp can prevent most colorectal cancers from ever forming.
  • The double-contrast barium enema is an alternative imaging test that is appropriate particularly when CTC is not available.
  • Imaging tests including CTC and the double-contrast barium enema are usually not indicated for colorectal cancer screening in high-risk patients with polyposis syndromes or inflammatory bowel disease.
  • [MeSH-minor] Adenoma / complications. Biopsy. Colitis, Ulcerative / radiography. Colonography, Computed Tomographic / methods. Colonoscopy / statistics & numerical data. Crohn Disease / radiography. Humans. Risk Assessment. Survival Rate. Tomography, X-Ray Computed / methods. United States / epidemiology


78. Bafandeh Y, Khoshbaten M, Eftekhar Sadat AT, Farhang S: Clinical predictors of colorectal polyps and carcinoma in a low prevalence region: results of a colonoscopy based study. World J Gastroenterol; 2008 Mar 14;14(10):1534-8
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical predictors of colorectal polyps and carcinoma in a low prevalence region: results of a colonoscopy based study.
  • Adenomatous polyps were detected in 56 (11.7%) patients, in 12.3% of men and 10.9% of women.
  • The mean age of the patients with a polyp was significantly higher than the others (49.53 +/- 14.16 vs 41.85 +/- 16.26, P = 0.001).
  • Most of the adenomatous polyps were left sided and tubular; only 22.5% of polyps were more than 10 mm.
  • The mean age of patients with cancer was significantly higher than the others (60.25 +/- 8.26 vs 42.13 +/- 16.08, P < 0.005) and higher than patients with polyps [60.25 (8.26) vs 49.53 (1.91) (P < 0.0005)].
  • None of the symptoms (diarrhea, abdominal pain, rectal bleeding, constipation, altering diarrhea and constipation, history of cancer, known irritable bowel disease, history of polyp and fissure or family history of cancer) were predictors for cancer or polyps, but the age of the patient and unexplained anemia independently predicted cancer.
  • Colonic symptoms are not predictors for polyps or cancer but unexplained anemia and elder age can predict CRC.
  • [MeSH-major] Adenoma / diagnosis. Adenoma / epidemiology. Colonic Polyps / diagnosis. Colonic Polyps / epidemiology. Colorectal Neoplasms / diagnosis. Colorectal Neoplasms / epidemiology

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Int J Colorectal Dis. 2000 Feb;15(1):29-34 [10766088.001]
  • [Cites] J Cancer Res Ther. 2005 Oct-Dec;1(4):204-7 [17998654.001]
  • [Cites] Am J Gastroenterol. 2000 Dec;95(12):3615-9 [11151901.001]
  • [Cites] East Mediterr Health J. 1999 Jul;5(4):766-77 [11338699.001]
  • [Cites] Public Health Nutr. 2002 Feb;5(1A):149-55 [12027278.001]
  • [Cites] Gastroenterol Clin North Am. 2002 Jun;31(2):565-86 [12134619.001]
  • [Cites] Dis Colon Rectum. 2002 Aug;45(8):1035-40 [12195187.001]
  • [Cites] J Korean Med Sci. 2002 Oct;17(5):604-10 [12378009.001]
  • [Cites] Gastroenterol Clin North Am. 2002 Dec;31(4):971-99 [12489273.001]
  • [Cites] J Med Assoc Thai. 2004 Jan;87(1):41-6 [14971533.001]
  • [Cites] Int J Cancer. 2004 May 1;109(5):777-81 [14999789.001]
  • [Cites] Dis Colon Rectum. 2004 Apr;47(4):481-5 [14994108.001]
  • [Cites] Am Surg. 2004 Mar;70(3):259-64 [15055851.001]
  • [Cites] ANZ J Surg. 2004 Jul;74(7):547-9 [15230787.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2004 Jul;13(7):1215-22 [15247133.001]
  • [Cites] Am J Surg Pathol. 2004 Nov;28(11):1460-5 [15489649.001]
  • [Cites] Ann Surg. 1971 Dec;174(6):1002-8 [5132429.001]
  • [Cites] Am J Surg. 1976 Feb;131(2):185-91 [175719.001]
  • [Cites] Cancer. 1977 Jan;39(1):274-8 [832242.001]
  • [Cites] Cancer. 1977 May;39(5):2258-64 [870171.001]
  • [Cites] Pathol Annu. 1977;12 Pt 1:87-116 [917598.001]
  • [Cites] Cancer. 1988 Apr 1;61(7):1472-6 [3345499.001]
  • [Cites] Gastroenterology. 1991 Apr;100(4):1033-40 [2001800.001]
  • [Cites] Am J Gastroenterol. 1995 Mar;90(3):353-65 [7872270.001]
  • [Cites] Ann Intern Med. 1995 Dec 15;123(12):904-10 [7486484.001]
  • [Cites] Cancer. 1996 Sep 15;78(6):1187-94 [8826939.001]
  • [Cites] Int J Colorectal Dis. 1997;12(5):267-71 [9401839.001]
  • [Cites] Postgrad Med J. 2004 Nov;80(949):667-9 [15537853.001]
  • [Cites] Br J Surg. 2005 Apr;92(4):478-81 [15609377.001]
  • [Cites] BMC Cancer. 2005;5:52 [15913456.001]
  • [Cites] Asian Pac J Cancer Prev. 2005 Apr-Jun;6(2):130-4 [16101320.001]
  • [Cites] Aliment Pharmacol Ther. 2005 Nov 1;22(9):859-64 [16225496.001]
  • [Cites] Asian Pac J Cancer Prev. 2006 Jan-Mar;7(1):65-8 [16629518.001]
  • [Cites] Orv Hetil. 2006 Apr 23;147(16):741-6 [16711260.001]
  • [Cites] Asian Pac J Cancer Prev. 2006 Apr-Jun;7(2):309-12 [16839228.001]
  • [Cites] Cancer Lett. 2006 Aug 18;240(1):143-7 [16288832.001]
  • [Cites] J Epidemiol. 2006 Nov;16(6):240-8 [17085874.001]
  • [Cites] AJR Am J Roentgenol. 2007 Mar;188(3):619-21 [17312044.001]
  • [Cites] Dis Colon Rectum. 2007 Jul;50(7):990-5 [17525859.001]
  • [Cites] N Engl J Med. 2000 Jul 20;343(3):162-8 [10900274.001]
  • (PMID = 18330943.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2693747
  •  go-up   go-down


79. Castillo-Alcala F, Mans C, Bos AS, Taylor WM, Smith DA: Clinical and pathologic features of an adenomatous polyp of the colon in a domestic ferret (Mustela putorius furo). Can Vet J; 2010 Nov;51(11):1261-4
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical and pathologic features of an adenomatous polyp of the colon in a domestic ferret (Mustela putorius furo).
  • The histopathological diagnosis of the resected mass was an adenomatous polyp of the colon.
  • [MeSH-major] Adenomatous Polyps / veterinary. Colonic Polyps / veterinary. Ferrets

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Am Anim Hosp Assoc. 1997 Mar-Apr;33(2):156-60 [9111726.001]
  • [Cites] J Am Vet Med Assoc. 1998 May 1;212(9):1402-6 [9589126.001]
  • [Cites] Vet Surg. 2006 Jun;35(4):337-40 [16756613.001]
  • [Cites] N Engl J Med. 2006 Dec 14;355(24):2551-7 [17167138.001]
  • [Cites] BMJ. 2000 Oct 7;321(7265):886-9 [11021873.001]
  • (PMID = 21286327.001).
  • [ISSN] 0008-5286
  • [Journal-full-title] The Canadian veterinary journal = La revue vétérinaire canadienne
  • [ISO-abbreviation] Can. Vet. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC2957035
  •  go-up   go-down


80. Rutter MD: Are adenomatous polyps rare in ulcerative colitis? Aliment Pharmacol Ther; 2005 Jan 1;21(1):98-9; author reply 99-100
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Are adenomatous polyps rare in ulcerative colitis?
  • [MeSH-major] Adenomatous Polyposis Coli / complications. Colitis, Ulcerative / complications

  • Genetic Alliance. consumer health - Ulcerative Colitis.
  • MedlinePlus Health Information. consumer health - Ulcerative Colitis.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentOn] Aliment Pharmacol Ther. 2004 Apr 15;19(8):879-87 [15080849.001]
  • (PMID = 15644053.001).
  • [ISSN] 0269-2813
  • [Journal-full-title] Alimentary pharmacology & therapeutics
  • [ISO-abbreviation] Aliment. Pharmacol. Ther.
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] England
  •  go-up   go-down


81. Farah-Klibi F, Kourda-Boujemaa J, Bouaskar I, Dziri C, Rachida Z, Jilani-Baltagi SB: Cystadenocarcinoma of the appendix: an incidental perioperatory finding in a patient with adenocarcinoma of the ascending and sigmoid colon: case report and review of literature. Pathologica; 2009 Dec;101(6):255-60
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cystadenocarcinoma of the appendix: an incidental perioperatory finding in a patient with adenocarcinoma of the ascending and sigmoid colon: case report and review of literature.
  • CASE PRESENTATION: A mucocele of the appendix, due to mucinous cystadenocarcinoma, was documented as an incidental perioperatory finding in a 68-year-old female.
  • Degenerated adenomatous polyp of the ascending colon and mucinous adenocarcinoma of the sigmoid colon invading the parietal peritoneum of the uterine and vagina was diagnosed.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20387715.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  •  go-up   go-down


82. Akyürek N, Salman B, Irkörücü O, Sare M, Tatlicioğlu E: Ultrasonography in the diagnosis of true gallbladder polyps: the contradiction in the literature. HPB (Oxford); 2005;7(2):155-8
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ultrasonography in the diagnosis of true gallbladder polyps: the contradiction in the literature.
  • Polypoid lesions of the gallbladder (PLGs) are often incidentally identified during ultrasonographic examination of abdominal pain.
  • Data were collected regarding the patients' gender, age, symptoms, serum lipid levels, the size and the number of polyps on US, surgical indications for PLGs and histopathological diagnosis.
  • Only 10 (18%) patients had adenomatous polyp and 8 of these polyps were larger than 1 cm.
  • Overall US-based diagnosis of gallbladder polyp was inaccurate in 82%.
  • The sensitivity and specificity of US for polyps <1 cm was 20% and 95.1%, respectively, whereas the sensitivity and specificity of US for polyps >1 cm was 80% and 99.3%, respectively.
  • The accuracy of US in diagnosing PLGs was poor, especially in polyps <1 cm.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Ann Surg. 1999 Apr;229(4):498-504 [10203082.001]
  • [Cites] Am J Gastroenterol. 1998 Sep;93(9):1518-23 [9732935.001]
  • [Cites] J Gastroenterol. 2001 Sep;36(9):619-22 [11578066.001]
  • [Cites] Br J Surg. 1992 Mar;79(3):227-9 [1555088.001]
  • [Cites] Scand J Gastroenterol. 1990 Mar;25(3):281-6 [2320947.001]
  • [Cites] Arch Surg. 1988 Jan;123(1):26-9 [3276295.001]
  • [Cites] J Clin Pathol. 1987 May;40(5):524-9 [3584503.001]
  • [Cites] Arch Pathol. 1970 Nov;90(5):423-32 [4319984.001]
  • [Cites] Radiology. 1983 Mar;146(3):593-601 [6402801.001]
  • [Cites] Gastroenterology. 1982 Apr;82(4):607-15 [7060883.001]
  • [Cites] Surgery. 1995 May;117(5):481-7 [7740417.001]
  • [Cites] Scand J Gastroenterol. 1994 May;29(5):480 [8036465.001]
  • [Cites] Am J Gastroenterol. 1997 Nov;92(11):2066-8 [9362194.001]
  • [Cites] J Clin Gastroenterol. 1997 Oct;25(3):518-21 [9412968.001]
  • [Cites] Arch Surg. 1998 Jul;133(7):735-9 [9688001.001]
  • [Cites] Am J Surg. 2001 Jan;181(1):65-70 [11248179.001]
  • (PMID = 18333181.001).
  • [ISSN] 1365-182X
  • [Journal-full-title] HPB : the official journal of the International Hepato Pancreato Biliary Association
  • [ISO-abbreviation] HPB (Oxford)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2023942
  •  go-up   go-down


83. Sotoudehmanesh R, Ainechi S, Asgari AA, Kolahdoozan S: Endoscopic lesions in low-to average-risk patients with minimal bright red bleeding from midline anal fissures. How much should we go in? Tech Coloproctol; 2007 Dec;11(4):340-2
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Adenomatous polyps were found in 4 cases (3.0%), ulcerative colitis in 8 (6.0%) and Crohn's disease in one patient (0.7%).

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Gastrointestinal Bleeding.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Hong Kong Med J. 2003 Jun;9(3):171-4 [12777651.001]
  • [Cites] Gut. 1982 Oct;23(10):835-42 [7117903.001]
  • [Cites] Int J Colorectal Dis. 2001 Aug;16(4):257-61 [11515686.001]
  • [Cites] Endoscopy. 2002 Aug;34(8):599-603 [12173078.001]
  • [Cites] J Fam Pract. 2004 Nov;53(11):879-84 [15527724.001]
  • [Cites] Am J Gastroenterol. 1998 Nov;93(11):2179-83 [9820393.001]
  • [Cites] Dis Colon Rectum. 1991 May;34(5):391-5 [2022144.001]
  • [Cites] Endoscopy. 1999 Oct;31(8):631-6 [10571136.001]
  • [Cites] Gastrointest Endosc. 1998 Dec;48(6):685-8 [9852474.001]
  • [Cites] Cancer. 1982 Feb 15;49(4):819-25 [7055790.001]
  • [Cites] Gastroenterology. 2003 Feb;124(2):544-60 [12557158.001]
  • [Cites] N Engl J Med. 2002 Jun 6;346(23):1781-5 [12050337.001]
  • (PMID = 18060528.001).
  • [ISSN] 1123-6337
  • [Journal-full-title] Techniques in coloproctology
  • [ISO-abbreviation] Tech Coloproctol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


84. Katabi N: Neoplasia of gallbladder and biliary epithelium. Arch Pathol Lab Med; 2010 Nov;134(11):1621-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Therefore, it is important to recognize the morphologic features of the biliary neoplasms to report a correct diagnosis. OBJECTIVES:.
  • (1) To discuss the differential diagnosis of dysplasia in the gallbladder and differentiate dysplasia from reactive atypia and invasive carcinoma, (2) review the histologic features of adenoma and polypoid biliary lesions, (3) highlight the differential diagnosis of adenocarcinoma in liver biopsy, and (4) discuss the differential diagnosis of atypical biliary glandular lesions.
  • [MeSH-major] Adenoma / pathology. Bile Duct Neoplasms / pathology. Carcinoma / pathology. Gallbladder Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Bile Duct Cancer.
  • MedlinePlus Health Information. consumer health - Gallbladder Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21043815.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  •  go-up   go-down


85. Solomon SD, Pfeffer MA, McMurray JJ, Fowler R, Finn P, Levin B, Eagle C, Hawk E, Lechuga M, Zauber AG, Bertagnolli MM, Arber N, Wittes J, APC and PreSAP Trial Investigators: Effect of celecoxib on cardiovascular events and blood pressure in two trials for the prevention of colorectal adenomas. Circulation; 2006 Sep 5;114(10):1028-35
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS AND RESULTS: The Adenoma Prevention With Celecoxib (APC) trial studied celecoxib 200 mg twice daily and 400 mg twice daily and the Prevention of Spontaneous Adenomatous Polyps (PreSAP) trial used 400 mg once daily totest the efficacy and safety of celecoxib against placebo in reducing colorectal adenoma recurrence after polypectomy.
  • Both dose groups in APC showed significant systolic blood pressure elevations at 1 and 3 years (200 mg twice daily: 1 year, 2.0 mm Hg; 3 years,2.6 mm Hg; 400 mg twice daily: 1 year, 2.9 mm Hg; 3 years, 5.2 mm Hg); however, the 400 mg once daily group inPreSAP did not (P0.0001 between studies).
  • [MeSH-major] Adenoma / prevention & control. Anti-Inflammatory Agents, Non-Steroidal / therapeutic use. Blood Pressure / drug effects. Colorectal Neoplasms / prevention & control. Pyrazoles / therapeutic use. Sulfonamides / therapeutic use

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • COS Scholar Universe. author profiles.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • Hazardous Substances Data Bank. CELECOXIB .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Circulation. 2007 Mar 27;115(12):e348; author reply e349 [17389275.001]
  • (PMID = 16943394.001).
  • [ISSN] 1524-4539
  • [Journal-full-title] Circulation
  • [ISO-abbreviation] Circulation
  • [Language] eng
  • [Databank-accession-numbers] ClinicalTrials.gov/ NCT00005094/ NCT00141193
  • [Publication-type] Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; 0 / Placebos; 0 / Pyrazoles; 0 / Sulfonamides; JCX84Q7J1L / Celecoxib
  •  go-up   go-down


86. O'Connor SD, Summers RM, Yao J, Pickhardt PJ, Choi JR: CT colonography with computer-aided polyp detection: volume and attenuation thresholds to reduce false-positive findings owing to the ileocecal valve. Radiology; 2006 Nov;241(2):426-32
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] CT colonography with computer-aided polyp detection: volume and attenuation thresholds to reduce false-positive findings owing to the ileocecal valve.
  • PURPOSE: To retrospectively identify volume and average attenuation thresholds for differentiating between ileocecal valve (ICV) and polyp at computed tomographic (CT) colonography with computer-aided detection (CAD).
  • A series of 2742 volume and attenuation thresholds, for which segmented findings both larger in volume and lower in average attenuation were labeled as ICVs and remaining findings were labeled polyps, were applied to the training set to determine settings with 100% sensitivity for polyp detection and the highest specificity for ICV detection.
  • RESULTS: A total of 386 ICVs and 67 adenomatous polyps from the training set and 102 ICVs and 138 adenomatous polyps from the test set could be segmented with a three-dimensional segmentation algorithm.
  • In the training set, a volume of 600 mm(3) and an attenuation of 36 HU provided 100% sensitivity (67 polyps; 95% CI: 93%, 100%) and the optimal 83% specificity (618 of 746 ICVs; 95% CI: 80%, 85%).
  • When applied to the test set, this combination provided 97% sensitivity (134 of 138 polyps; 95% CI: 92%, 99%) and 84% specificity (160 of 191 ICVs; 95% CI: 78%, 89%).
  • Differences in sensitivity and specificity in the detection of polyps between the sets were not significant.
  • CONCLUSION: Volume and average CT attenuation thresholds can help differentiate most ICVs from true polyps.
  • [MeSH-major] Colonic Polyps / radiography. Colonography, Computed Tomographic. Ileocecal Valve / radiography. Radiographic Image Interpretation, Computer-Assisted

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17005773.001).
  • [ISSN] 0033-8419
  • [Journal-full-title] Radiology
  • [ISO-abbreviation] Radiology
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / /
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
  • [Publication-country] United States
  •  go-up   go-down


87. Hao CY, Moore DH, Chiu YS, Wong P, Bennington JL, Smith AP, Chen LC, Lee NM: Altered gene expression in normal colonic mucosa of individuals with polyps of the colon. Dis Colon Rectum; 2005 Dec;48(12):2329-35
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Altered gene expression in normal colonic mucosa of individuals with polyps of the colon.
  • Here we report a study of individuals with no cancer but with polyps in the transverse, ascending/descending, or rectosigmoid colon.
  • METHODS: Biopsies of grossly normal-appearing colonic mucosa from the rectosigmoid colon were taken from individuals with polyps, with or without personal/family history of colon cancer, and gene expression profiles compared with those from biopsies of control patients, with no polyps or known personal/family history.
  • RESULTS: We found significant differences in gene expression in normal-appearing rectosigmoid colonic mucosa between individuals with polyps and controls, regardless of whether personal or family history of cancer was present.
  • CONCLUSIONS: Alterations in gene expression patterns in morphologically normal-appearing colonic mucosa are associated with the presence of adenomatous polyps.
  • [MeSH-major] Colonic Neoplasms / genetics. Colonic Polyps / genetics. Gene Expression Profiling

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16400515.001).
  • [ISSN] 0012-3706
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


88. Rao CV, Yang YM, Swamy MV, Liu T, Fang Y, Mahmood R, Jhanwar-Uniyal M, Dai W: Colonic tumorigenesis in BubR1+/-ApcMin/+ compound mutant mice is linked to premature separation of sister chromatids and enhanced genomic instability. Proc Natl Acad Sci U S A; 2005 Mar 22;102(12):4365-70
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The adenomatous polyposis coli (Apc) gene also plays an important role in regulating genomic stability, as mutations of Apc cause aneuploidy.
  • Here we show that whereas Apc(Min)(/+) mice developed many adenomatous polyps, mostly in the small intestine, by 3 mo of age; BubR1(+/-)Apc(Min)(/+) compound mutant mice developed 10 times more colonic tumors than Apc(Min)(/+) mice.

  • COS Scholar Universe. author profiles.
  • Gene Ontology. gene/protein/disease-specific - Gene Ontology annotations from this paper .
  • KOMP Repository. gene/protein/disease-specific - KOMP Repository (subscription/membership/fee required).
  • Mouse Genome Informatics (MGI). Mouse Genome Informatics (MGI) .
  • SciCrunch. OMIM: Data: Gene Annotation .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Cell. 2000 Jun 9;101(6):635-45 [10892650.001]
  • [Cites] Cell. 1997 May 30;89(5):727-35 [9182760.001]
  • [Cites] Nature. 2001 Jan 18;409(6818):355-9 [11201745.001]
  • [Cites] Curr Biol. 2001 Jan 9;11(1):44-9 [11166179.001]
  • [Cites] Cancer Res. 2001 Feb 1;61(3):818-22 [11221861.001]
  • [Cites] Hum Mol Genet. 2001 Apr;10(7):721-33 [11257105.001]
  • [Cites] Nat Cell Biol. 2001 Apr;3(4):429-32 [11283619.001]
  • [Cites] Nat Cell Biol. 2001 Apr;3(4):433-8 [11283620.001]
  • [Cites] Cell. 2001 Jun 1;105(5):563-6 [11389825.001]
  • [Cites] Mol Cell. 2002 Sep;10(3):439-40 [12408813.001]
  • [Cites] J Cell Biol. 2003 Feb 3;160(3):341-53 [12551952.001]
  • [Cites] Nat Rev Cancer. 2003 Sep;3(9):695-701 [12951588.001]
  • [Cites] J Cell Biol. 2003 Dec 8;163(5):949-61 [14662741.001]
  • [Cites] Nature. 1998 Dec 17;396(6712):643-9 [9872311.001]
  • [Cites] Nat Rev Mol Cell Biol. 2004 Jan;5(1):45-54 [14708009.001]
  • [Cites] Cancer Res. 2004 Jan 15;64(2):440-5 [14744753.001]
  • [Cites] Blood. 2004 Feb 15;103(4):1278-85 [14576056.001]
  • [Cites] Curr Opin Genet Dev. 2004 Feb;14(1):11-6 [15108799.001]
  • [Cites] Mol Biol Cell. 2004 Jun;15(6):2978-91 [15075372.001]
  • [Cites] Nat Genet. 2004 Jul;36(7):744-9 [15208629.001]
  • [Cites] Nat Genet. 2004 Nov;36(11):1159-61 [15475955.001]
  • [Cites] Nat Genet. 2004 Nov;36(11):1144-5 [15514664.001]
  • [Cites] Nature. 1987 Aug 13-19;328(6131):614-6 [3039373.001]
  • [Cites] Cell. 1991 Aug 9;66(3):589-600 [1651174.001]
  • [Cites] Science. 1991 Aug 9;253(5020):661-5 [1651562.001]
  • [Cites] Nature. 1992 Sep 17;359(6392):235-7 [1528264.001]
  • [Cites] Nat Genet. 1994 Mar;6(3):217-9 [8012377.001]
  • [Cites] Cell. 1996 Nov 29;87(5):803-9 [8945508.001]
  • [Cites] Nature. 1997 Apr 10;386(6625):623-7 [9121588.001]
  • [Cites] Cell. 2000 Oct 13;103(2):311-20 [11057903.001]
  • (PMID = 15767571.001).
  • [ISSN] 0027-8424
  • [Journal-full-title] Proceedings of the National Academy of Sciences of the United States of America
  • [ISO-abbreviation] Proc. Natl. Acad. Sci. U.S.A.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA110057; United States / NCI NIH HHS / CA / CA90658; United States / NCI NIH HHS / CA / R01 CA080003; United States / NCI NIH HHS / CA / R03 CA110057; United States / NCI NIH HHS / CA / CA80003; United States / NCI NIH HHS / CA / R01 CA090658
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Bub1b protein, mouse; 0 / Cell Cycle Proteins; EC 2.7.- / Protein Kinases; EC 2.7.11.1 / Bub1 spindle checkpoint protein; EC 2.7.11.1 / Protein-Serine-Threonine Kinases
  • [Other-IDs] NLM/ PMC555497
  •  go-up   go-down


89. John BJ, Irukulla S, Pilgrim G, Swift I, Abulafi AM: Surveillance colonoscopies for colorectal polyps--too often, too many! An Audit at a Large District General Hospital. Colorectal Dis; 2008 Nov;10(9):898-900
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surveillance colonoscopies for colorectal polyps--too often, too many! An Audit at a Large District General Hospital.
  • INTRODUCTION: The British society of Gastroenterologists (BSG) have laid down guidelines for surveillance colonoscopies in patients with large bowel adenomatous polyps.
  • We audited our practice of polyp management and looked at guideline compliance amongst patients on our colonoscopic surveillance list.
  • METHOD: All patients undergoing adenoma surveillance and those with newly detected adenomas over a 2-month period were included in the first loop of the audit.
  • Amongst those on surveillance for polyps, compliance was ascertained as regards need for procedure and appropriateness of surveillance interval.
  • Of the patients on our colonoscopic waiting list for adenomatous polyps, 17.7% satisfied guidelines, 23.4% did not require any further surveillance and 58.9% were booked for a procedure earlier than recommended.
  • [MeSH-major] Colonic Polyps / surgery. Colonoscopy / utilization. Intestinal Polyps / surgery. Rectal Diseases / surgery

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • MedlinePlus Health Information. consumer health - Rectal Disorders.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19037930.001).
  • [ISSN] 1463-1318
  • [Journal-full-title] Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
  • [ISO-abbreviation] Colorectal Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  •  go-up   go-down


90. Siddiqui AA, Maddur H, Naik S, Cryer B: The association of elevated HbA1c on the behavior of adenomatous polyps in patients with type-II diabetes mellitus. Dig Dis Sci; 2008 Apr;53(4):1042-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The association of elevated HbA1c on the behavior of adenomatous polyps in patients with type-II diabetes mellitus.
  • The aim of our study was to determine whether poor control of diabetes mellitus (DM) is associated with increased prevalence of colonic adenomatous polyps (APs), especially those that are advanced .
  • Significant variables by UA were included in a stepwise logistic regression analysis to determine independent predictors of aggressive clinical behavior by the polyps.
  • All values are presented as means +/- SE, and statistical significance was determined at P < or = 0.05.
  • Logistic regression, as measured by HbA1c, demonstrated that poorly controlled DM-2 independently predicted a greater prevalence of right-sided AP, a more advanced lesion at the time of presentation, a greater number of polyps, and greater use of exogenous insulin.
  • [MeSH-major] Adenomatous Polyps / blood. Adenomatous Polyps / pathology. Colonic Neoplasms / blood. Colonic Neoplasms / pathology. Diabetes Mellitus, Type 2 / blood. Hemoglobin A, Glycosylated / metabolism

  • Genetic Alliance. consumer health - Diabetes.
  • MedlinePlus Health Information. consumer health - A1C.
  • MedlinePlus Health Information. consumer health - Diabetes Type 2.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Science. 1978 Apr 7;200(4337):21-7 [635569.001]
  • [Cites] J Natl Cancer Inst. 2002 Jul 3;94(13):972-80 [12096082.001]
  • [Cites] Diabetes Care. 2003 Jan;26 Suppl 1:S33-50 [12502618.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2003 May;12(5):412-8 [12750235.001]
  • [Cites] Jpn J Cancer Res. 1989 Jan;80(1):51-8 [2540132.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 1996 Dec;5(12):1013-5 [8959325.001]
  • [Cites] Int J Epidemiol. 1998 Oct;27(5):794-8 [9839735.001]
  • [Cites] J Gen Intern Med. 2000 Aug;15(8):551-5 [10940146.001]
  • [Cites] Annu Rev Public Health. 2005;26:445-67 [15760297.001]
  • [Cites] Br J Cancer. 2001 Feb 2;84(3):417-22 [11161410.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2005 Apr;14(4):850-5 [15824155.001]
  • [Cites] Clin Chem. 1986 Oct;32(10 Suppl):B64-70 [3530542.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2004 Jun;13(6):915-9 [15184246.001]
  • [Cites] Gastroenterol Clin North Am. 2002 Dec;31(4):925-43 [12489270.001]
  • [Cites] Clin Biochem. 1998 Jun;31(4):221-8 [9646944.001]
  • [Cites] Lancet. 1998 Sep 12;352(9131):837-53 [9742976.001]
  • [Cites] Semin Gastrointest Dis. 2000 Oct;11(4):194-206 [11057947.001]
  • [Cites] Gut. 1999 Jul;45(1):45-50 [10369703.001]
  • [Cites] J Nutr. 2001 Nov;131(11 Suppl):3109S-20S [11694656.001]
  • [Cites] Ann Intern Med. 1993 Oct 15;119(8):836-43 [8379605.001]
  • [Cites] CA Cancer J Clin. 2006 Mar-Apr;56(2):106-30 [16514137.001]
  • [Cites] Gastroenterology. 2005 Aug;129(2):464-75 [16083703.001]
  • [Cites] N Engl J Med. 1993 Dec 30;329(27):1977-81 [8247072.001]
  • [Cites] Nutr Cancer. 1997;27(3):316-20 [9101563.001]
  • [Cites] Carcinogenesis. 1985 Jul;6(7):1063-6 [4017173.001]
  • [Cites] Lancet. 2004 Apr 24;363(9418):1346-53 [15110491.001]
  • [Cites] Am J Epidemiol. 1998 May 1;147(9):816-25 [9583711.001]
  • [Cites] Cancer Causes Control. 1995 Mar;6(2):164-79 [7749056.001]
  • [Cites] Arch Intern Med. 2004 Nov 8;164(20):2235-40 [15534160.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2001 Sep;10(9):937-41 [11535544.001]
  • [Cites] Carcinogenesis. 1993 Apr;14(4):777-9 [8472347.001]
  • [Cites] J Clin Invest. 1995 Apr;95(4):1897-905 [7706497.001]
  • [Cites] Br J Surg. 2001 Jan;88(1):107-13 [11136321.001]
  • [Cites] J Natl Cancer Inst. 1999 Mar 17;91(6):542-7 [10088625.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 1996 Aug;5(8):607-12 [8824362.001]
  • [Cites] Ann Intern Med. 2004 Jun 1;140(11):945-50 [15172919.001]
  • [Cites] Diabetes Care. 1992 Jul;15(7):815-9 [1516497.001]
  • [Cites] Clin Gastroenterol Hepatol. 2006 Oct;4(10):1225-31 [16979948.001]
  • [Cites] Am J Gastroenterol. 2006 Aug;101(8):1872-9 [16790032.001]
  • (PMID = 17939046.001).
  • [ISSN] 0163-2116
  • [Journal-full-title] Digestive diseases and sciences
  • [ISO-abbreviation] Dig. Dis. Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Blood Glucose; 0 / Hemoglobin A, Glycosylated; 0 / hemoglobin A1c protein, human
  •  go-up   go-down


91. Thirlwell C, Howarth KM, Segditsas S, Guerra G, Thomas HJ, Phillips RK, Talbot IC, Gorman M, Novelli MR, Sieber OM, Tomlinson IP: Investigation of pathogenic mechanisms in multiple colorectal adenoma patients without germline APC or MYH/MUTYH mutations. Br J Cancer; 2007 Jun 4;96(11):1729-34
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Investigation of pathogenic mechanisms in multiple colorectal adenoma patients without germline APC or MYH/MUTYH mutations.
  • Based on the precedent of MYH-associated polyposis (MAP), we searched for a mutational signature in 241 adenomatous polyps from our MCRA cases.
  • In sharp contrast to MAP tumours, we did not find evidence of a specific mutational signature in any individual patient or in the overall set of MCRA cases.
  • These results suggest that hypermutation of APC does not cause our patients' disease and strongly suggests that MAP is not a paradigm for the remaining MCRA patients.
  • Our MCRA patients' colons showed no evidence of microadenomas, unlike in MAP and familial adenomatous polyposis (FAP).
  • [MeSH-major] Adenoma / genetics. Colorectal Neoplasms / genetics. DNA Glycosylases / genetics. Genes, APC. Germ-Line Mutation
  • [MeSH-minor] Adenomatous Polyposis Coli / genetics. Adult. Aged. Gene Expression Regulation, Neoplastic. Gene Frequency. Genetic Predisposition to Disease. Humans. Loss of Heterozygosity. Middle Aged. beta Catenin / genetics

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Hum Genet. 1999 Nov;105(5):388-98 [10598803.001]
  • [Cites] Gut. 2006 Oct;55(10):1440-8 [16461775.001]
  • [Cites] Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9719-23 [11481457.001]
  • [Cites] Gut. 2001 Oct;49(4):540-3 [11559652.001]
  • [Cites] Nat Genet. 2002 Feb;30(2):227-32 [11818965.001]
  • [Cites] Hum Mol Genet. 2002 Jun 15;11(13):1549-60 [12045208.001]
  • [Cites] Am J Pathol. 2002 Jun;160(6):2055-61 [12057910.001]
  • [Cites] N Engl J Med. 2003 Feb 27;348(9):791-9 [12606733.001]
  • [Cites] J Med Genet. 2003 Apr;40(4):e35 [12676908.001]
  • [Cites] Oncogene. 2003 Jul 3;22(27):4257-65 [12833148.001]
  • [Cites] Lancet. 2003 Jul 5;362(9377):39-41 [12853198.001]
  • [Cites] Cancer Res. 2003 Nov 15;63(22):7595-9 [14633673.001]
  • [Cites] Nucleic Acids Res. 1998 Jan 1;26(1):269-70 [9399850.001]
  • [Cites] Nat Med. 1999 Sep;5(9):1071-5 [10470088.001]
  • [Cites] Am J Hum Genet. 1999 Nov;65(5):1291-8 [10521294.001]
  • [Cites] Hum Mol Genet. 2000 Sep 22;9(15):2215-21 [11001924.001]
  • (PMID = 17505512.001).
  • [ISSN] 0007-0920
  • [Journal-full-title] British journal of cancer
  • [ISO-abbreviation] Br. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / beta Catenin; EC 3.2.2.- / DNA Glycosylases; EC 3.2.2.- / mutY adenine glycosylase
  • [Other-IDs] NLM/ PMC2359923
  •  go-up   go-down


92. Siddiqui A, Pena Sahdala HN, Nazario HE, Mahgoub A, Patel M, Cipher D, Spechler S: Obesity is associated with an increased prevalence of advanced adenomatous colon polyps in a male veteran population. Dig Dis Sci; 2009 Jul;54(7):1560-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Obesity is associated with an increased prevalence of advanced adenomatous colon polyps in a male veteran population.
  • Obesity has been associated with an increased risk for colonic adenomatous polyps (APs) and colorectal cancers, but the influence of obesity on the development of advanced APs is not clear.
  • We identified 2,903 male patients with APs (mean age 64 + 1.1(SE) years; 770 (27%) normal weight, 1,029 (35%) overweight, 1,104 (38%) obese.
  • For every one-unit increase in BMI above 30, there was a corresponding 1% increase in the frequency of finding advanced APs.
  • Obesity in male veteran patients is associated with the finding of advanced APs on colonoscopy.
  • [MeSH-major] Adenomatous Polyps / epidemiology. Colonic Neoplasms / epidemiology. Obesity / epidemiology

  • Genetic Alliance. consumer health - Obesity.
  • MedlinePlus Health Information. consumer health - Obesity.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Am J Gastroenterol. 2001 Jul;96(7):2238-46 [11467659.001]
  • [Cites] Am J Clin Nutr. 1988 Feb;47(2):312-7 [3341261.001]
  • [Cites] J Natl Cancer Inst. 2002 Jul 3;94(13):972-80 [12096082.001]
  • [Cites] Clin Gastroenterol Hepatol. 2007 Aug;5(8):982-90 [17553754.001]
  • [Cites] Jpn J Cancer Res. 1989 Jan;80(1):51-8 [2540132.001]
  • [Cites] N Engl J Med. 2003 Mar 6;348(10):891-9 [12621133.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 1996 Dec;5(12):1013-5 [8959325.001]
  • [Cites] Intern Med. 2009;48(3):123-8 [19182421.001]
  • [Cites] J Gastroenterol. 2007 Aug;42(8):616-23 [17701124.001]
  • [Cites] J Nutr. 2001 Nov;131(11 Suppl):3109S-20S [11694656.001]
  • [Cites] N Engl J Med. 2005 May 26;352(21):2184-92 [15917383.001]
  • [Cites] Oncogene. 1999 Nov 22;18(49):6853-66 [10602461.001]
  • [Cites] N Engl J Med. 2003 Mar 6;348(10):883-90 [12621132.001]
  • [Cites] Gastroenterology. 2005 Aug;129(2):464-75 [16083703.001]
  • [Cites] N Engl J Med. 1993 Dec 30;329(27):1977-81 [8247072.001]
  • [Cites] Int J Colorectal Dis. 1987 Nov;2(4):203-7 [3694018.001]
  • [Cites] Br J Cancer. 1987 Jun;55(6):687-94 [3620314.001]
  • [Cites] Nutr Cancer. 1997;27(3):316-20 [9101563.001]
  • [Cites] Cancer Causes Control. 1996 Mar;7(2):253-63 [8740738.001]
  • [Cites] Jpn J Cancer Res. 1996 Aug;87(8):798-804 [8797885.001]
  • [Cites] Lancet. 2004 Apr 24;363(9418):1346-53 [15110491.001]
  • [Cites] N Engl J Med. 1992 Mar 5;326(10):658-62 [1736104.001]
  • [Cites] J Clin Invest. 1995 Apr;95(4):1897-905 [7706497.001]
  • [Cites] Br J Surg. 2001 Jan;88(1):107-13 [11136321.001]
  • [Cites] CA Cancer J Clin. 2008 Mar-Apr;58(2):71-96 [18287387.001]
  • [Cites] J Natl Cancer Inst. 1991 Mar 6;83(5):355-8 [1759994.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2005 Sep;14(9):2082-6 [16172213.001]
  • [Cites] J Natl Cancer Inst. 1991 Mar 6;83(5):359-61 [1995919.001]
  • [Cites] Am J Epidemiol. 1998 Apr 1;147(7):670-80 [9554606.001]
  • [Cites] Scand J Gastroenterol. 1999 Apr;34(4):414-20 [10365903.001]
  • [Cites] Int J Oncol. 2003 Oct;23(4):1055-69 [12963986.001]
  • [Cites] N Engl J Med. 1991 Dec 5;325(23):1593-6 [1669840.001]
  • [Cites] Nutr Cancer. 2001;39(1):50-7 [11588902.001]
  • (PMID = 19399615.001).
  • [ISSN] 1573-2568
  • [Journal-full-title] Digestive diseases and sciences
  • [ISO-abbreviation] Dig. Dis. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


93. Goto H, Oda Y, Murakami Y, Tanaka T, Hasuda K, Goto S, Sasaki Y, Sakisaka S, Hattori M: Proportion of de novo cancers among colorectal cancers in Japan. Gastroenterology; 2006 Jul;131(1):40-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND & AIMS: Adenomatous polyps are main precursors of colorectal cancers (CRCs).
  • In Japan, de novo cancers, which do not arise from preexisting adenomas, are considered to account for a substantial number of CRCs, but the relative importance of de novo carcinogenesis remains controversial.
  • Early cancers among CRCs detected in this study were classified as de novo cancers or polyp cancers derived from adenomas.
  • There were no differences with regard to size and location between de novo cancers and polyp cancers, but morphology differed.
  • [MeSH-minor] Adult. Aged. Colonic Polyps / epidemiology. Colonic Polyps / pathology. Female. Humans. Incidence. Intestinal Mucosa / pathology. Japan / epidemiology. Male. Middle Aged. Retrospective Studies. Risk Factors. Sex Distribution

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Gastroenterology. 2006 Oct;131(4):1361; author reply 1361-2 [17030215.001]
  • (PMID = 16831588.001).
  • [ISSN] 0016-5085
  • [Journal-full-title] Gastroenterology
  • [ISO-abbreviation] Gastroenterology
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


94. Palozza P, Serini S, Maggiano N, Tringali G, Navarra P, Ranelletti FO, Calviello G: beta-Carotene downregulates the steady-state and heregulin-alpha-induced COX-2 pathways in colon cancer cells. J Nutr; 2005 Jan;135(1):129-36
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Experimental studies have shown that beta-carotene inhibited the growth of colon cancer cells, and human trials have demonstrated that the carotenoid reduces colon cell proliferation of adenomatous polyps; however, molecular mechanisms underlying this chemopreventive activity remain unclear.
  • We evaluated the effects of beta-carotene on the growth of human colon adenocarcinoma cells overexpressing (LS-174, HT-29, WiDr) or not expressing (HCT116) COX-2.
  • This effect was not observed in cells treated with retinoic acid or retinol.
  • Moreover, cells not expressing COX-2 were insensitive to the growth-inhibitory and proapoptotic effects of the carotenoid.

  • Hazardous Substances Data Bank. BETA-CAROTENE .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15623844.001).
  • [ISSN] 0022-3166
  • [Journal-full-title] The Journal of nutrition
  • [ISO-abbreviation] J. Nutr.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Isoenzymes; 0 / Membrane Proteins; 0 / Neuregulin-1; 0 / Reactive Oxygen Species; 0 / heregulin alpha; 01YAE03M7J / beta Carotene; EC 1.14.99.1 / Cyclooxygenase 1; EC 1.14.99.1 / Cyclooxygenase 2; EC 1.14.99.1 / PTGS1 protein, human; EC 1.14.99.1 / PTGS2 protein, human; EC 1.14.99.1 / Prostaglandin-Endoperoxide Synthases; EC 2.7.11.24 / Extracellular Signal-Regulated MAP Kinases; EC 3.4.22.- / CASP3 protein, human; EC 3.4.22.- / Caspase 3; EC 3.4.22.- / Caspases; K7Q1JQR04M / Dinoprostone
  •  go-up   go-down


95. van den Broek I, Sparidans RW, Engwegen JY, Cats A, Depla AC, Schellens JH, Beijnen JH: Evaluation of human neutrophil peptide-1, -2 and -3 as serum markers for colorectal cancer. Cancer Biomark; 2010;7(2):109-15
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Serum was obtained from patients with indications for colonoscopy, subsequently diagnosed as normal colon or hyperplastic polyp (CON; n= 368), adenomatous polyp (AP; n = 179) or colorectal cancer (CRC; n = 69).


96. Nam JH, Yang CH: [Clinical characteristics and risk factors of colon polyps in gyeongju and pohang area]. Korean J Gastroenterol; 2008 Sep;52(3):142-9
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clinical characteristics and risk factors of colon polyps in gyeongju and pohang area].
  • BACKGROUND/AIMS: The purposes of this study were to investigate various environmental factors for colon polyps and to analyze locoregional clinical characteristics of colon polyps in Gyeongju and Pohang area.
  • METHODS: From October 2005 to September 2006, patients who underwent colonoscopy were analyzed based on their ages, genders, body mass indices (BMI), dietary habits, smoking behaviors, accompaying diseases, and medications as risk factors for the occurrence of colon polyps.
  • Then clinical manifestations, gross appearances and pathologic findings of polyps were investigated.
  • RESULTS: Among 253 patients enrolled, a total of 296 colon polyps were found in 108 patients.
  • The incidence of colon polyps in more than 50-year old patients was 3.2-fold greater compared to less than 50-year old patients.
  • Smoking habits were also significantly associated with the occurence of colon polyps.
  • Among adenomatous polyps, tubulovillous type and moderate to severe dysplasia were frequently observed as the size increased, yet the location of polyps was not significantly associated.
  • CONCLUSIONS: Older age and smoking habit increase the risk of colon polyps.
  • Rectal polyps have less chance to be adenomatous type.
  • The larger the polyp grows, the more likely it to be tubulovillous and dysplastic.
  • [MeSH-major] Colonic Polyps / diagnosis. Colorectal Neoplasms / diagnosis
  • [MeSH-minor] Adenomatous Polyps / pathology. Adult. Aged. Aged, 80 and over. Female. Humans. Korea. Male. Middle Aged. Multivariate Analysis. Odds Ratio. Risk Factors. Rural Population. Surveys and Questionnaires

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19077510.001).
  • [ISSN] 1598-9992
  • [Journal-full-title] The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
  • [ISO-abbreviation] Korean J Gastroenterol
  • [Language] kor
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Korea (South)
  •  go-up   go-down


97. Levi Z, Vilkin A, Niv Y: Esophago-gastro-duodenoscopy is not indicated in patients with positive immunochemical test and nonexplanatory colonoscopy. Eur J Gastroenterol Hepatol; 2010 Dec;22(12):1431-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Esophago-gastro-duodenoscopy is not indicated in patients with positive immunochemical test and nonexplanatory colonoscopy.
  • In this study, we evaluated EGD findings in patients with positive immunochemical fecal occult blood test (I-FOBT) not explained by colonoscopy.
  • METHODS: Out of 1221 consecutive patients having total colonoscopy after preparing I-FOBT (OC-MICRO, with threshold of 75 or 100 ngHb/ml), we included only patients without colorectal cancer or advanced adenomatous polyp on colonoscopy, who also underwent EGD within 4 months of the fecal blood testing.
  • CONCLUSION: Immunological FOBT positivity was not correlated with the finding of lesions, which are likely to bleed on EGD.
  • Thus, EGD is probably not indicated in patients with positive I-FOBT and unrevealing colonoscopy.

  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • MedlinePlus Health Information. consumer health - Gastrointestinal Bleeding.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20962660.001).
  • [ISSN] 1473-5687
  • [Journal-full-title] European journal of gastroenterology & hepatology
  • [ISO-abbreviation] Eur J Gastroenterol Hepatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  •  go-up   go-down


98. Sjursen W, Bjørnevoll I, Engebretsen LF, Fjelland K, Halvorsen T, Myrvold HE: A homozygote splice site PMS2 mutation as cause of Turcot syndrome gives rise to two different abnormal transcripts. Fam Cancer; 2009;8(3):179-86
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Turcot syndrome is a rare, inherited disease predisposing of tumours in the central nerve system and in the colorectal system.
  • She has since then been treated for multiple cancers (gastrointestinal, endometrial, basal cell carcinomas), and removal of adenomatous polyps at several occasions.
  • The patients genotype was found to be a homozygous splice site mutation in the PMS2 gene, c.989-1G<T, which resulted in two abnormal transcripts, not one as expected.
  • [MeSH-major] Adenomatous Polyposis Coli / genetics. Adenosine Triphosphatases / genetics. DNA Repair Enzymes / genetics. DNA-Binding Proteins / genetics

  • Genetic Alliance. consumer health - Turcot syndrome.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] EMBO J. 2001 Oct 1;20(19):5521-31 [11574484.001]
  • [Cites] Eur J Pediatr. 2008 Feb;167(2):225-9 [17387511.001]
  • [Cites] Oncogene. 2000 Mar 23;19(13):1719-23 [10763829.001]
  • [Cites] Nat Genet. 2002 Feb;30(2):227-32 [11818965.001]
  • [Cites] Cancer Res. 2004 Jul 15;64(14 ):4721-7 [15256438.001]
  • [Cites] Fam Cancer. 2001;1(2):101-5 [14574005.001]
  • [Cites] Gastroenterology. 2005 May;128(5):1431-6 [15887124.001]
  • [Cites] Cell. 1999 Apr 2;97(1):85-97 [10199405.001]
  • [Cites] J Natl Cancer Inst. 2006 Mar 1;98 (5):358-61 [16507833.001]
  • [Cites] Cell. 1991 Aug 9;66(3):589-600 [1651174.001]
  • [Cites] J Clin Oncol. 1997 Jul;15(7):2744-58 [9215849.001]
  • [Cites] Hum Mutat. 2006 May;27(5):490-5 [16619239.001]
  • [Cites] Cancer Res. 1997 Sep 1;57(17):3798-803 [9288790.001]
  • [Cites] J Neurosurg. 1991 May;74(5):813-5 [1849556.001]
  • [Cites] J Med Genet. 2002 Oct;39(10):754-7 [12362034.001]
  • [Cites] FEBS Lett. 2007 Jun 19;581(15):2845-53 [17531985.001]
  • [Cites] Cancer Res. 2001 Jun 1;61(11):4545-9 [11389088.001]
  • [Cites] Gastroenterology. 2006 Feb;130(2):312-22 [16472587.001]
  • [Cites] N Engl J Med. 1995 Mar 30;332(13):839-47 [7661930.001]
  • [Cites] Hum Mol Genet. 2002 Nov 1;11(23):2961-7 [12393807.001]
  • [Cites] Dis Colon Rectum. 1959 Sep-Oct;2:465-8 [13839882.001]
  • [Cites] J Neurosurg. 1999 May;90(5):946-50 [10223463.001]
  • [Cites] Atherosclerosis. 1999 Sep;146(1):125-31 [10487495.001]
  • [Cites] Gastroenterology. 2005 May;128(5):1506-9 [15887130.001]
  • [Cites] Gastroenterology. 2005 May;128(5):1160-71 [15887099.001]
  • [Cites] Genomics. 1995 Nov 20;30(2):195-206 [8586419.001]
  • [Cites] N Engl J Med. 1998 May 21;338(21):1481-7 [9593786.001]
  • [Cites] Am J Gastroenterol. 2005 Aug;100(8):1886-91 [16144131.001]
  • [Cites] Am J Hum Genet. 2004 May;74(5):954-64 [15077197.001]
  • [Cites] Cancer Genet Cytogenet. 2005 Feb;157(1):82-6 [15676154.001]
  • [Cites] Cancer Res. 1997 Aug 1;57(15):3288-93 [9242462.001]
  • (PMID = 19039682.001).
  • [ISSN] 1573-7292
  • [Journal-full-title] Familial cancer
  • [ISO-abbreviation] Fam. Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / DNA, Complementary; 0 / DNA-Binding Proteins; EC 3.6.1.- / Adenosine Triphosphatases; EC 3.6.1.- / PMS2 protein, human; EC 3.6.1.3 / Mismatch Repair Endonuclease PMS2; EC 6.5.1.- / DNA Repair Enzymes
  •  go-up   go-down


99. Botma A, Nagengast FM, Braem MG, Hendriks JC, Kleibeuker JH, Vasen HF, Kampman E: Body mass index increases risk of colorectal adenomas in men with Lynch syndrome: the GEOLynch cohort study. J Clin Oncol; 2010 Oct 1;28(28):4346-53
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The objective of this study was to assess whether BMI is associated with colorectal adenoma occurrence in persons with LS.
  • This association was not observed among women (overweight v normal weight HR, 0.75; 95% CI, 0.19 to 3.07), nor was it observed in the prevalent cohort.
  • In the incident cohort, height was statistically significantly associated with a decreased risk of adenomatous polyps among men (per 5 cm HR, 0.43; 95% CI, 0.23 to 0.83), but the association between weight and adenomatous polyps among men was of marginal significance (per 5 kg HR, 1.17; 95% CI, 1.00 to 1.37).
  • [MeSH-major] Adenoma / epidemiology. Body Mass Index. Colorectal Neoplasms / epidemiology. Colorectal Neoplasms, Hereditary Nonpolyposis / epidemiology


100. Loh K, Chia JA, Greco S, Cozzi SJ, Buttenshaw RL, Bond CE, Simms LA, Pike T, Young JP, Jass JR, Spring KJ, Leggett BA, Whitehall VL: Bone morphogenic protein 3 inactivation is an early and frequent event in colorectal cancer development. Genes Chromosomes Cancer; 2008 Jun;47(6):449-60
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Methylation was also frequently observed in serrated and traditional adenomatous polyps (22/29, 76%).
  • [MeSH-minor] Adaptor Proteins, Signal Transducing / genetics. Adenoma / genetics. Adenoma / metabolism. Bone Morphogenetic Protein 3. Cell Line, Tumor. Cohort Studies. Colonic Polyps / genetics. Colonic Polyps / metabolism. Colorectal Neoplasms, Hereditary Nonpolyposis / genetics. Colorectal Neoplasms, Hereditary Nonpolyposis / metabolism. CpG Islands. Disease Progression. Humans. Intestinal Mucosa / metabolism. Loss of Heterozygosity. Microsatellite Instability. Nuclear Proteins / genetics. Precancerous Conditions / genetics. Precancerous Conditions / metabolism. Promoter Regions, Genetic / genetics. Subtraction Technique. Tumor Stem Cell Assay






Advertisement