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1. Li WW, Yau TN, Leung CW, Pong WM, Chan MY: Large-cell neuroendocrine carcinoma of the uterine cervix complicating pregnancy. Hong Kong Med J; 2009 Feb;15(1):69-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Large-cell neuroendocrine carcinoma of the uterine cervix complicating pregnancy.
  • Large-cell neuroendocrine cervical carcinoma is a rare and aggressive cancer that tends to spread and recur early despite intensive multimodal treatment.
  • We report a patient with clinically stage IIB large-cell neuroendocrine cervical carcinoma who presented with a cervical polyp and vaginal bleeding at 18 weeks of pregnancy.


2. Mousavi A, Akhavan S: Sarcoma botryoides (embryonal rhabdomyosarcoma) of the uterine cervix in sisters. J Gynecol Oncol; 2010 Dec 30;21(4):273-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sarcoma botryoides (embryonal rhabdomyosarcoma) of the uterine cervix in sisters.
  • Sarcoma botryoides (embryonal rhabdomyosarcoma) rarely arises in the uterine cervix.
  • We report a case of a 14-year-old female with sarcoma botryoides who presented with prolonged vaginal bleeding and cervical polyp.
  • Presence of sarcoma botryoides of the cervix in two sisters in the family highlights the possible role of genetic factors in the development of sarcoma botryoides.

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  • (PMID = 21278891.001).
  • [ISSN] 2005-0399
  • [Journal-full-title] Journal of gynecologic oncology
  • [ISO-abbreviation] J Gynecol Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC3026308
  • [Keywords] NOTNLM ; Cervical cancer / Rhabdomyosarcoma / Sarcoma botryoides
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3. Godfrey GJ, Moore G, Alatassi H: Presentation of renal cell carcinoma as cervical polyp metastasis. J Low Genit Tract Dis; 2010 Oct;14(4):387-9
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  • [Title] Presentation of renal cell carcinoma as cervical polyp metastasis.
  • Secondary cervical adenocarcinomas are most commonly seen owing to the extension of a primary endometrial adenocarcinoma.
  • We report a case of metastatic renal cell carcinoma, clear cell variant, to the cervix, which presented as a cervical polyp in a postmenopausal female.
  • To our knowledge, this is the fourth reported case of renal cell carcinoma metastatic to the cervix.
  • This case is only the third in which the cervical metastasis was the presenting sign of renal cell carcinoma and the first in which the clinical presentation was as a cervical polyp.
  • [MeSH-major] Carcinoma, Renal Cell / diagnosis. Carcinoma, Renal Cell / secondary. Polyps / pathology. Uterine Cervical Neoplasms / diagnosis. Uterine Cervical Neoplasms / secondary


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4. Kuroda N, Hirano K, Ohara M, Hirouchi T, Mizuno K, Kubo A, Enzan H: Adenoid basal carcinoma arising in the cervical polyp: an immunohistochemical study of stromal cells. Med Mol Morphol; 2007 Jun;40(2):112-4
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  • [Title] Adenoid basal carcinoma arising in the cervical polyp: an immunohistochemical study of stromal cells.
  • Adenoid basal carcinomas of the uterine cervix are uncommon neoplasms and generally run a favorable clinical course.
  • A 40-year-old woman was found to have a cervical polyp during a medical checkup and underwent polypectomy.
  • Immunohistochemically, a smaller number of CD34-positive and CD31-negative stromal cells, namely fibroblasts, in the stroma of tumor center than in normal cervical stroma were observed.
  • Gynecologists and pathologists should bear in mind that adenoid basal carcinoma may arise in a cervical polyp.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Carcinoma, Adenoid Cystic / pathology. Neoplasms, Basal Cell / pathology. Polyps / pathology. Stromal Cells / metabolism. Uterine Cervical Neoplasms / pathology

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  • (PMID = 17572848.001).
  • [ISSN] 1860-1480
  • [Journal-full-title] Medical molecular morphology
  • [ISO-abbreviation] Med Mol Morphol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Biomarkers, Tumor
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5. Goh SG, Chuah KL, Chew SH, Tan PH: Uterine epithelioid endometrial stromal sarcoma presenting as a "cervical polyp". Ann Diagn Pathol; 2005 Apr;9(2):101-5
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  • [Title] Uterine epithelioid endometrial stromal sarcoma presenting as a "cervical polyp".
  • Although appearance of conventional uterine endometrial stromal sarcoma is easily recognized on histology, it may uncommonly assume unusual appearances such as uterine tumor resembling ovarian sex-cord tumor, thereby hindering its diagnosis.
  • In this report, we detail yet another instance where this tumor adopted an epithelioid morphology, presenting itself as a polyp extruding from the cervical os in a 41-year-old Chinese woman.
  • [MeSH-major] Endometrial Neoplasms / diagnosis. Polyps / diagnosis. Sarcoma, Endometrial Stromal / diagnosis. Uterine Cervical Neoplasms / diagnosis


6. Bucella D, Frédéric B, Noël JC: Giant cervical polyp: a case report and review of a rare entity. Arch Gynecol Obstet; 2008 Sep;278(3):295-8
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  • [Title] Giant cervical polyp: a case report and review of a rare entity.
  • BACKGROUND: If cervical polyps are a common pathology in the female adult population, giant cervical polyps with a size greater than 4 cm are rare and until now only several cases have been described in literature.
  • The size and the clinical presentation can mimic a cervical neoplasia.
  • CASE REPORT: We report the case of a giant cervical polyp of 5.5 cm occurring in a multiparous 47-year-old woman who clinically presented vaginal bleeding.
  • [MeSH-major] Polyps / pathology. Uterine Cervical Diseases / pathology

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  • (PMID = 18236053.001).
  • [ISSN] 1432-0711
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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7. Dugalic V, Gojnic M, Brankovic M, Stojanovic I, Ser F, Zizic V: Bone metastasis arising from a polyp of the cervix as the first symptom in generalized multi-organ adenocarcinoma. Eur J Gynaecol Oncol; 2010;31(5):593-5
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  • [Title] Bone metastasis arising from a polyp of the cervix as the first symptom in generalized multi-organ adenocarcinoma.
  • After two vaginal deliveries without any reported difficulties, the patient had no intermenstrual bleeding, postcoital bleeding, leucorrhea or hypermenorrhea, abnormal vaginal bleeding, or postmenstrual bleeding, except during the past five-year period when a polyp-like change in the cervix was found.
  • During Werthaim-Meigs surgery, four positive glandules and cervical adenocarcinoma Stage II were found.
  • Unfortunately, considering the changes in the tissue of the colon and cervix, we considered the condition to be "generalized" adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / secondary. Bone Neoplasms / secondary. Neoplasms, Multiple Primary / diagnosis. Neoplasms, Multiple Primary / pathology. Uterine Cervical Neoplasms / pathology


8. Alameda F, Bellosillo B, Baró T, Pijuan L, Baldrich C, Losa Dominguez F, Munne A, Lloreta J, Serrano S: Large cell lymphoma-like reaction in a cervical polyp. Gynecol Oncol; 2005 Nov;99(2):481-5
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  • [Title] Large cell lymphoma-like reaction in a cervical polyp.
  • BACKGROUND: Inflammatory lesions of the uterine cervix are very common, and although lymphomas in this location are rare, the differential diagnosis between both diseases must be considered in some cases and may be difficult to achieve.
  • CASE: A 37-year-old woman in good health with a cervical polyp, showing a lymphoma-like reaction with blastic appearance, which was initially interpreted as a diffuse large-cell lymphoma.
  • [MeSH-major] Lymphoma, Large B-Cell, Diffuse / diagnosis. Polyps / diagnosis. Uterine Cervical Neoplasms / diagnosis


9. Ou KY, Chen YC, Hsu SC, Tsai EM: Hysteroscopic management of lower genital tract lesions in females with limited vaginal access. Fertil Steril; 2009 Jan;91(1):293.e9-11

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  • DESIGN: Retrospective review of two patients who received hysteroscopy for evaluation of uterus didelphys with hemivagina and a cervical polyp.
  • PATIENT(S): Two patients with either a vagina septum or cervical polyp.
  • MAIN OUTCOME MEASURE(S): Resection of a vagina septum and cervical polyp.
  • RESULT(S): No more cyclic dysmenorrhea in the patient with uterus didelphys and cessation of abnormal bleeding in the patient with a cervical polyp.
  • Our results suggest that hysteroscopy can provide precise visualization of vagina and cervical lesions if the approach is difficult with decreased access, and allows concurrent treatment of pathologic conditions accordingly.
  • CONCLUSION(S): Hysteroscopy is favorable in the diagnosis and treatment of vaginal and cervical lesions in women with limited vaginal access because of age or a narrower vagina.
  • [MeSH-minor] Adult. Child. Dysmenorrhea / etiology. Female. Humans. Hymen / anatomy & histology. Hymen / pathology. Magnetic Resonance Imaging. Retrospective Studies. Uterine Diseases / surgery. Vaginal Diseases / surgery

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  • (PMID = 17412334.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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10. Gojnic M, Filimonovic D, Arsenijevic Lj, Popovic N, Dugalic V, Jeremic V, Tulic I, Radonjic G, Pervulov M, Argirovic R: Cervical and duodenal polyps and their malignant alterations--case report. Eur J Gynaecol Oncol; 2007;28(1):69-71
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  • [Title] Cervical and duodenal polyps and their malignant alterations--case report.
  • During routine examination of a 32-year-old patient, a cervical polyp was found and CIN III was confirmed by biopsy.
  • After performing colposcopy, biopsy and establishing CIN III as well as performing gastroscopy where a duodenal polyp was found, thorough diagnostic exams and therapy were carried out.
  • [MeSH-major] Duodenal Diseases / surgery. Neoplasms, Multiple Primary / pathology. Peutz-Jeghers Syndrome / pathology. Uterine Cervical Diseases / pathology. Uterine Cervical Neoplasms / pathology


11. Bagga R, Keepanasseril A, Srinivasan R, Dey P, Gainder S, Saha SC, Dhaliwal LK, Patel F: Adenosarcoma of the uterine cervix with heterologous elements: a case report and review of literature. Arch Gynecol Obstet; 2010 Apr;281(4):669-75
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  • [Title] Adenosarcoma of the uterine cervix with heterologous elements: a case report and review of literature.
  • Till date, more than 100 cases of mullerian adenosarcoma of the cervix with homologous elements have been reported.
  • However, only 15 cases of mullerian adenosarcoma of the cervix with heterologous elements are reported.
  • MATERIALS AND METHODS: We describe a case of mullerian adenosarcoma with heterologous elements of rhabdomyosarcoma and benign cartilage presenting as a cervical polyp in a young girl.
  • CONCLUSION: Cervical adenosarcomas are rare tumors that may appear in reproductive age.
  • [MeSH-major] Adenosarcoma / pathology. Cervix Uteri / pathology. Uterine Cervical Neoplasms / pathology

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  • (PMID = 19685064.001).
  • [ISSN] 1432-0711
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 33
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12. Singh AM, Konjengbam R, Devi SS, Devi NP: Leiomyosarcoma of uterus--a case report. J Indian Med Assoc; 2006 Mar;104(3):142, 144, 147
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  • It may arise from the uterine myometrium de novo or may be transformed from a pre-existing benign leiomyoma.
  • A 55-year-old female presenting with 20-22 weeks size of uterus and bleeding per vagina was clinically diagnosed as a case of leiomyoma uteri and cervical polyp, was subjected to abdominal hysterectomy.
  • The tumour mass was later confirmed histologically as leiomyosarcoma of uterus presumed to be transformed from pre-existing leiomyoma uteri.
  • [MeSH-major] Hysterectomy. Leiomyosarcoma / pathology. Leiomyosarcoma / surgery. Uterine Neoplasms / pathology. Uterine Neoplasms / surgery

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  • (PMID = 16910338.001).
  • [ISSN] 0019-5847
  • [Journal-full-title] Journal of the Indian Medical Association
  • [ISO-abbreviation] J Indian Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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13. Van Renterghem N, De Paepe P, Van den Broecke R, Bourgain C, Serreyn R: Primary lymphoma of the cervix uteri: a diagnostic challenge. Report of two cases and review of the literature. Eur J Gynaecol Oncol; 2005;26(1):36-8
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  • [Title] Primary lymphoma of the cervix uteri: a diagnostic challenge. Report of two cases and review of the literature.
  • BACKGROUND: Primary non Hodgkin's lymphoma (NHL) of the cervix and vagina is uncommon; the incidence of uterine lymphoma is estimated to be less than 0.5% of all NHL.
  • CASES: We report two cases of primary diffuse large B-cell lymphoma of the cervix.
  • The second case presented as a cervical polyp.
  • [MeSH-major] Lymphoma, B-Cell / diagnosis. Uterine Cervical Neoplasms / diagnosis


14. Chandacham A, Kietpeerakool C, Khunamornpong S, Suprasert P, Srisomboon J, Charoenkwan K, Phongnarisorn C, Cheewakraingkrai C, Siriaree S, Tantipalakorn C: Successfully conservative treatment of large cervical choriocarcinoma with profuse vaginal bleeding. J Med Assoc Thai; 2009 Jan;92(1):120-3
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  • [Title] Successfully conservative treatment of large cervical choriocarcinoma with profuse vaginal bleeding.
  • Primary choriocarcinoma of the uterine cervix is a rare disease.
  • Furthermore, the majority of cases presented with abnormal vaginal bleeding that could be caused by other more common conditions including, threatened abortion, cervical polyp, cervical pregnancy, or cervical cancer.
  • In the present report, the authors present a case of large cervical choriocarcinoma with life-threatening vaginal bleeding, which was initially misdiagnosed as a cervical cancer The active cervical bleeding was successfully controlled with selective uterine arterial embolization.
  • Remission of cervical choriocarcinoma was accomplished with combination chemotherapy without the need of hysterectomy.
  • [MeSH-major] Choriocarcinoma / therapy. Pregnancy Complications, Neoplastic / therapy. Uterine Neoplasms / therapy

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  • (PMID = 19260253.001).
  • [ISSN] 0125-2208
  • [Journal-full-title] Journal of the Medical Association of Thailand = Chotmaihet thangphaet
  • [ISO-abbreviation] J Med Assoc Thai
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Thailand
  • [Chemical-registry-number] 04079A1RDZ / Cytarabine; 6PLQ3CP4P3 / Etoposide; BZ114NVM5P / Mitoxantrone; MEA protocol
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15. Stamatellos I, Stamatopoulos P, Bontis J: The role of hysteroscopy in the current management of the cervical polyps. Arch Gynecol Obstet; 2007 Oct;276(4):299-303
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  • [Title] The role of hysteroscopy in the current management of the cervical polyps.
  • The current management of patients with cervical polyps may include different approaches and protocols, such as a simply removal of the polyp in most cases at an office setting, surgical dilatation and curettage, electrosurgical excision or hysteroscopic polypectomy.
  • Exploration of the cervical canal and uterine cavity by hysteroscopy determines the exact origin of the polyp pedicle (cervical or endometrial) and if there is any concurrent endometrial pathology.
  • The majority of cervical polyps are asymptomatic, and their incidence is increasing with age.
  • Symptomatic cervical polyps may cause intermenstrual bleeding, postcoital bleeding, heavy menses, postmenopausal bleeding and vaginal discharge.
  • Cervical polyps may be detected by routine gynaecological examination, colposcopy, filling defects on hysterosalpingogram, gynaecological ultrasound (abdominal, transvaginal or sonohysterography) or endometrial biopsy.
  • The location, number, and size of cervical polyps are best determined with diagnostic hysteroscopy.
  • In the past, simple twisting or avulsion of the polyp or blind curettage was the standard surgical treatment of choice.
  • However, this treatment often leaves residual polyp fragments in the cervical canal.
  • In addition, up to 25% of patients who have cervical polyp, have also a coexisting endometrial polyp, so there is a need for evaluation of the endometrial cavity.
  • It is important to note the usefulness of hysteroscopy to manage a patient with a cervical polyp, especially when she presents abnormal uterine bleeding, in order to make an accurate diagnosis and offer appropriate treatment.
  • [MeSH-major] Hysteroscopy. Polyps / diagnosis. Polyps / surgery. Uterine Cervical Neoplasms / diagnosis. Uterine Cervical Neoplasms / surgery

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  • (PMID = 17653740.001).
  • [ISSN] 0932-0067
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 40
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16. Terada T: Large endocervical polyp with cartilaginous and osseous metaplasia: a hitherto unreported entity. Int J Gynecol Pathol; 2009 Jan;28(1):98-100
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  • [Title] Large endocervical polyp with cartilaginous and osseous metaplasia: a hitherto unreported entity.
  • The author reports a previously unrecognized entity of cervical polyp with cartilaginous and osseous metaplasia.
  • A colposcopic examination revealed a large endocervical polyp (12 x 13 x 30 mm), and a polypectomy was performed.
  • Microscopically, the polyp was covered by a layer of columnar epithelium.
  • The pathologic diagnosis was endocervical polyp with cartilaginous and osseous metaplasia.
  • [MeSH-major] Bone and Bones / pathology. Cartilage / pathology. Polyps / pathology. Uterine Cervical Diseases / pathology

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  • (PMID = 19047901.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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17. Srilatha PS, Roy A: Villoglandular papillary adenocarcinoma of cervix associated with cervical intraepithelial neoplasia: a case report and review of literature. Indian J Pathol Microbiol; 2007 Oct;50(4):819-21
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  • [Title] Villoglandular papillary adenocarcinoma of cervix associated with cervical intraepithelial neoplasia: a case report and review of literature.
  • Well differentiated villoglandular adenocarcinoma of uterine cervix is a rare tumour which usually occurs in young women.
  • Physical examination revealed a cervical polyp.
  • Histopathological findings were consistent with villoglandular papillary adenocarcinoma associated with high grade cervical intraepithelial neoplasia (CIN-3).
  • [MeSH-major] Adenocarcinoma, Papillary / complications. Adenocarcinoma, Papillary / pathology. Cervical Intraepithelial Neoplasia / complications. Cervical Intraepithelial Neoplasia / pathology. Uterine Cervical Neoplasms / complications. Uterine Cervical Neoplasms / pathology
  • [MeSH-minor] Adnexa Uteri / pathology. Adult. Antineoplastic Agents / therapeutic use. Cisplatin / therapeutic use. Female. Humans. Hydronephrosis. Polyps. Ureter / pathology


18. Schnatz PF, Ricci S, O'Sullivan DM: Cervical polyps in postmenopausal women: is there a difference in risk? Menopause; 2009 May-Jun;16(3):524-8
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  • [Title] Cervical polyps in postmenopausal women: is there a difference in risk?
  • OBJECTIVE: The aim of this study was to evaluate cervical polyps and assess whether postmenopausal women are at higher risk for abnormalities than their premenopausal counterparts.
  • For the women younger than 50 years, the prevalence of malignancy, dysplasia, and atypia within a cervical polyp was 0.1%, 0.7%, and 1.9%, respectively, compared with 0.1%, 0.2%, and 1.1% for the women 50 years or older (P = 0.846, 0.063, and 0.144, respectively).
  • The prevalence of "any abnormality" (malignancy, dysplasia, or atypia) within the polyp among women younger than 50 years was 2.7% compared with 1.4% in women 50 years or older (P = 0.034).
  • CONCLUSIONS: The prevalence of any abnormality within a cervical polyp is significantly lower in postmenopausal, compared with premenopausal, women.
  • Younger women (teenagers to 20s) have little risk associated with cervical polyps.
  • Women in the perimenopausal to postmenopausal years have a slightly higher likelihood of a malignancy associated with cervical polyps.
  • [MeSH-major] Polyps / pathology. Postmenopause. Uterine Cervical Dysplasia / pathology. Uterine Cervical Neoplasms / pathology

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  • (PMID = 19179926.001).
  • [ISSN] 1530-0374
  • [Journal-full-title] Menopause (New York, N.Y.)
  • [ISO-abbreviation] Menopause
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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19. Rahimi K, Shaw PA, Chetty R: Solitary fibrous tumor of the uterine cervix. Int J Gynecol Pathol; 2010 Mar;29(2):189-92
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  • [Title] Solitary fibrous tumor of the uterine cervix.
  • A 68-year-old woman with stage pT1b1 N0 cervical squamous carcinoma had an incidental cervical polyp.
  • The polyp measured 1.7 cm in maximal diameter and histologic evaluation showed it to be composed of spindle-shaped cells with hypercellular and hypocellular foci.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Solitary Fibrous Tumors / pathology. Uterine Cervical Neoplasms / pathology

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  • (PMID = 20173506.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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20. Tsikouras P, Galazios G, Liberis V, Bouzaki A, Grapsas X, Maroulis G: TV sonographic assessment in postmenopausal asymptomatic women. Eur J Gynaecol Oncol; 2007;28(6):473-6
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  • In the remaining 123 postmenopausal women with suspicious endometrium > 5 mm, 19 endometrial polyps (7.13%), one cervical polyp with extension in the cavity (0.8%), 90 endometrial atrophies (73.17%), ten atrophic endometritis (8.13%), two simple hyperplasias (1.62%), and one hyperplasia with atypia (0.8%) were found.

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  • (PMID = 18179139.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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21. Siddon A, Hui P: Glial heterotopia of the uterine cervix: DNA genotyping confirmation of its fetal origin. Int J Gynecol Pathol; 2010 Jul;29(4):394-7
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Glial heterotopia of the uterine cervix: DNA genotyping confirmation of its fetal origin.
  • Uterine glial heterotopia is a rare, yet biologically intriguing lesion, mostly involving the cervix.
  • We investigated a case of polypoid glial heterotopia of the uterine cervix in a 42-year-old woman who underwent an elective termination of pregnancy of a Down syndrome fetus.
  • Gross and microscopic examination revealed a 2.5 cm polypoid cervical lesion consisting of lobulated mature glial tissue covered by endocervical glandular epithelium.
  • DNA genotyping of the cervical polyp, maternal, first and second fetal tissue samples showed an identical genetic profile between the cervical glial tissue and the first aborted fetus.
  • Therefore, this molecular case investigation confirms the fetal origin of uterine glial heterotopia.
  • [MeSH-major] Glial Fibrillary Acidic Protein / metabolism. S100 Proteins / metabolism. Uterine Cervical Neoplasms / pathology

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  • (PMID = 20567155.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm; 0 / Glial Fibrillary Acidic Protein; 0 / S100 Proteins
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22. Yi KW, Song SH, Kim KA, Jung WY, Lee JK, Hur JY: Giant endocervical polyp mimicking cervical malignancy: primary excision and hysteroscopic resection. J Minim Invasive Gynecol; 2009 Jul-Aug;16(4):498-500
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  • [Title] Giant endocervical polyp mimicking cervical malignancy: primary excision and hysteroscopic resection.
  • Giant cervical polyps are characterized by an unusually large size and appear clinically as malignant.
  • The final histopathologic findings confirmed a benign giant cervical polyp.
  • [MeSH-major] Polyps / pathology. Uterine Cervical Diseases / pathology

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  • (PMID = 19573830.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Serpins; 0 / squamous cell carcinoma-related antigen
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23. Yin LR, Sun JJ, Ma HD, Mi SL, Guo SJ, Shi Y: [Expression of interleukin1-alpha, beta and interferon-gamma in macrophages from endometrium of women with endometriosis]. Zhonghua Fu Chan Ke Za Zhi; 2006 May;41(5):295-8
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  • Cervical polyp tissue was used as positive control.

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  • (PMID = 16762180.001).
  • [ISSN] 0529-567X
  • [Journal-full-title] Zhonghua fu chan ke za zhi
  • [ISO-abbreviation] Zhonghua Fu Chan Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Interleukin-1; 0 / Interleukin-1alpha; 0 / Interleukin-1beta; 0 / RNA, Messenger; 82115-62-6 / Interferon-gamma
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24. Dray M, Russell P, Dalrymple C, Wallman N, Angus G, Leong A, Carter J, Cheerala B: p16(INK4a) as a complementary marker of high-grade intraepithelial lesions of the uterine cervix. I: Experience with squamous lesions in 189 consecutive cervical biopsies. Pathology; 2005 Apr;37(2):112-24
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

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  • [Title] p16(INK4a) as a complementary marker of high-grade intraepithelial lesions of the uterine cervix. I: Experience with squamous lesions in 189 consecutive cervical biopsies.
  • AIM: To test the usefulness of p16(INK4a) immunostaining for improving the diagnostic accuracy of cervical punch biopsies referred to a routine laboratory setting during the investigation of women with abnormal Papanicolaou smears.
  • METHODS: A total of 188 consecutive and unselected colposcopically directed cervical biopsies and a single contemporaneous cervical polyp were accessioned prospectively over a 3-month period, step-serially sectioned and examined by H&E and immunostained for p16(INK4a).
  • The clinical context, results of concurrent Papanicolaou smears/ThinPrep slides and Digene hybrid capture tests for high-risk human papillomavirus (HPV) subtypes, as well as follow-up cervical smears/ThinPrep, biopsies and loop excisions of transformation zones or cone biopsies were all correlated with the morphological and immunohistochemical findings.
  • RESULTS: Seventy-seven biopsies (40.7%) displayed a high-grade squamous intraepithelial lesion (HGSIL; cervical intraepithelial neoplasia [CIN] 2-3), 27 (14.3%) showed a low grade squamous intraepithelial lesion (HPV +/- CIN1) and 85 (45%) showed a range of non-dysplastic (inflammatory or reactive) changes.
  • Diffuse strong parabasal immunostaining for p16(INK4a), suggestive of integrated high-risk HPV DNA into the host genome, was observed in 81 biopsies (42.9%, including the cervical polyp) and correlated (>90%) with HGSIL in the H&E sections.
  • CONCLUSIONS: Thus, within a routine diagnostic laboratory, p16(INK4a) immunostaining appears to be a very useful adjunctive test in the examination of colposcopically directed cervical biopsies, in the diagnostic cascade of women investigated for abnormal Papanicolaou smears.
  • It is possible, as further data accumulate concerning the importance of integration of high-risk HPV DNA into the host cell genome and the reliability with which this can be identified by p16(INK4a) immunostaining, that this will become the diagnostic 'lesion of interest', replacing the subjective histological grading of cervical dysplasia, in the management of such patients; i.e., the discriminatory watershed between continued surveillance and active intervention.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Carcinoma, Squamous Cell / pathology. Cervical Intraepithelial Neoplasia / pathology. Cyclin-Dependent Kinase Inhibitor p16 / metabolism. Precancerous Conditions / pathology. Uterine Cervical Neoplasms / pathology

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  • [CommentIn] Pathology. 2006 Apr;38(2):190-1; author reply191-2 [16581668.001]
  • (PMID = 16028838.001).
  • [ISSN] 0031-3025
  • [Journal-full-title] Pathology
  • [ISO-abbreviation] Pathology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / DNA, Viral
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25. Sahu B, Latheef R, Aboel Magd S: Prevalence of pathology in women attending colposcopy for postcoital bleeding with negative cytology. Arch Gynecol Obstet; 2007 Nov;276(5):471-3
International Agency for Research on Cancer - Screening Group. diagnostics - Colposcopy and Treatment of Cervical Intraepithelial Neoplasia: A Beginner's Manual .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To determine the frequency of cervical pathology and the incidence of cervical neoplasia in women presenting with PCB at the colposcopy clinic with negative cytology.
  • RESULTS: Six women (6.9%) had cervical intraepithelial neoplasia.
  • Other identifiable causes were cervical polyp (12.5%), ectopy (33.6%) and Chlamydia (2.3%).
  • CONCLUSION: Women with postcoital bleeding even with normal smears appear to be at much greater risk of cervical neoplasia than the general population.
  • [MeSH-major] Cervical Intraepithelial Neoplasia / epidemiology. Coitus. Colposcopy / utilization. Uterine Cervical Neoplasms / epidemiology. Uterine Hemorrhage / etiology


26. Sun AJ, Lin SQ, Jing LH, Wang ZY, Ye JL, Zhang Y: [Safety of promestriene capsule used in postmenopausal atrophic vaginitis]. Zhonghua Fu Chan Ke Za Zhi; 2009 Aug;44(8):593-6
Hazardous Substances Data Bank. ESTRADIOL .

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  • They all showed significant difference (P < 0.01). (3) Adverse effect: six cases with vaginal bleeding, 3 cases with breast nodules and 1 case with cervical polyp was observed, however, it was uncertain whether those events were associated with promestriene use.

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  • (PMID = 20003787.001).
  • [ISSN] 0529-567X
  • [Journal-full-title] Zhonghua fu chan ke za zhi
  • [ISO-abbreviation] Zhonghua Fu Chan Ke Za Zhi
  • [Language] chi
  • [Publication-type] Clinical Trial; English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Capsules; 0 / Vaginal Creams, Foams, and Jellies; 4TI98Z838E / Estradiol; GXM4PER6WZ / promestriene
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27. Visnovsky J, Zubor P, Galo S, Klobusiaková D, Fiolka R, Kajo K: [Validity of hysteroscopy in clinical setting: single centre analysis of 605 consecutive hysteroscopies]. Ceska Gynekol; 2008 Dec;73(6):365-9
MedlinePlus Health Information. consumer health - Uterine Diseases.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: Hysteroscopy represent standard diagnostic and therapeutic method in the treatment of endometrial pathology, where patient selection for this procedure depends in majority on preoperative uterine ultrasound scan.
  • The most frequent indication for hysteroscopy was history of postmenopausal bleeding (35.88%), followed by endometrial polyp (30.9%), hyperplasia (28.24%), cervical polyp (2.32%), corpus alienum in the uterus (1.66%) and fertility disorders (1%).
  • Multifactorial analysis of hysteroscopy, ultrasound and histopathological findings revealed 69.41% sensitivity rate for ultrasound finding of endometrial hyperplasia, 48.16% sensitivity rate for submucous myoma and 81.72% sensitivity for endometrial polyp.
  • The association between hysteroscopic and histopathological results showed a 97.1% agreement in patients with endometrial polyp and 89.3% agreement for cases with endometrial hyperplasia (p<0.05).
  • Out of all surgical procedures polyp ablation represented 63.2%, resection of submucous fibroids 21.2%, endometrial resection or ablation 7.2% and 8.4% others procedures.
  • In studied population we diagnosed 18 (3%) cases of endometrial carcinoma (13 cases associated with hyperplasia, 5 with polyp).
  • The most frequent surgical complication was perforation of the uterine cavity (three cases 0.50%), followed by fluid overload syndrome (0.17%).
  • The validity of sonography in case of hyperplasia prior surgery could be improved by control uterine ultrasound scan reflecting cycle phase one-two days before surgery.

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  • (PMID = 19170372.001).
  • [ISSN] 1210-7832
  • [Journal-full-title] Ceska gynekologie
  • [ISO-abbreviation] Ceska Gynekol
  • [Language] CZE
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Czech Republic
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28. Abu-Rustum NR, Su W, Levine DA, Boyd J, Sonoda Y, Laquaglia MP: Pediatric radical abdominal trachelectomy for cervical clear cell carcinoma: a novel surgical approach. Gynecol Oncol; 2005 Apr;97(1):296-300
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pediatric radical abdominal trachelectomy for cervical clear cell carcinoma: a novel surgical approach.
  • INTRODUCTION: Clear cell carcinoma of the cervix and vagina is rare in the pediatric population.
  • Radical abdominal or vaginal trachelectomy and pelvic lymph node dissection is a new technique utilized in adult women with early cervical cancer who wish to retain fertility.
  • The resection includes the cervix, upper vagina, parametrium, and paracolpos.
  • Vaginoscopy revealed cervical polyp in both cases.
  • They underwent radical abdominal trachelectomy and bilateral pelvic lymph node dissection along with anastomosis of uterine isthmus to upper vagina.
  • Intraoperative frozen-section analysis confirmed negative uterine and vaginal margins.
  • CONCLUSION: To our knowledge, this is the first report of radical abdominal trachelectomy in the pediatric age group and it is likely to include the youngest patient with clear cell carcinoma of the uterine cervix not associated with DES exposure.
  • [MeSH-major] Adenocarcinoma, Clear Cell / surgery. Gynecologic Surgical Procedures / methods. Uterine Cervical Neoplasms / surgery

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  • (PMID = 15790482.001).
  • [ISSN] 0090-8258
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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29. Arora R, El-Hameed AA, Al Ajrawi T: Significance of intracytoplasmic crystalline inclusions in plasma cells - a review with case discussion. Gulf J Oncolog; 2009 Jul;(6):51-5
International Agency for Research on Cancer - Screening Group. diagnostics - Histopathology and cytopathology of the uterine cervix - digital atlas .

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  • We reviewed the literature and present clinical, morphological and immunohistochemical findings in a polyp of the cervix.
  • The polyp showed extensive plasma cell infiltrate with needle shaped and elongated intracytoplasmic inclusions in many of them.
  • This case highlights the fact that the presence of intracytoplasmic crystalline inclusions should not be considered pathognomonic of B-cell lymphoproliferative disorder.
  • [MeSH-major] Inclusion Bodies / pathology. Plasma Cells / pathology. Polyps / pathology. Uterine Cervical Neoplasms / pathology

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  • (PMID = 20194091.001).
  • [ISSN] 2078-2101
  • [Journal-full-title] The Gulf journal of oncology
  • [ISO-abbreviation] Gulf J Oncolog
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Kuwait
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30. Been MJ, Hinsely ML, Hartig GK: Fibrovascular polyp of the cervical esophagus. Am J Otolaryngol; 2009 Mar-Apr;30(2):134-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fibrovascular polyp of the cervical esophagus.

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  • (PMID = 19239955.001).
  • [ISSN] 1532-818X
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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