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1. Ulu EM, Uyuşur A, Ekici Y, Hunca C, Coşkun M: Multidetector CT findings of spontaneous rupture of hepatic adenoma in a patient with hepatic adenomatosis. Diagn Interv Radiol; 2009 Jun;15(2):135-8
MedlinePlus Health Information. consumer health - Liver Diseases.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multidetector CT findings of spontaneous rupture of hepatic adenoma in a patient with hepatic adenomatosis.
  • Hepatic adenomatosis (HA) is characterized by more than 10 adenomas in the liver, frequently scattered within both lobes.
  • On follow-up CT examination, a large adenoma was clearly visualized at the site of the previous hematoma.

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  • (PMID = 19517384.001).
  • [ISSN] 1305-3612
  • [Journal-full-title] Diagnostic and interventional radiology (Ankara, Turkey)
  • [ISO-abbreviation] Diagn Interv Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
  • [Chemical-registry-number] 0 / Contrast Media
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2. Lorenzo Garrido H, Rotaetxe Vacas O, García Barcina MJ, Muñoz García G, Martín Bejarano E: [Hepatic adenomatosis]. An Pediatr (Barc); 2008 May;68(5):526-7
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  • [Title] [Hepatic adenomatosis].
  • [Transliterated title] Adenomatosis hepática.

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  • (PMID = 18448003.001).
  • [ISSN] 1695-4033
  • [Journal-full-title] Anales de pediatría (Barcelona, Spain : 2003)
  • [ISO-abbreviation] An Pediatr (Barc)
  • [Language] spa
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Spain
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3. Svrcek M, Jeannot E, Arrivé L, Poupon R, Fromont G, Fléjou JF, Zucman-Rossi J, Bouchard P, Wendum D: Regressive liver adenomatosis following androgenic progestin therapy withdrawal: a case report with a 10-year follow-up and a molecular analysis. Eur J Endocrinol; 2007 Jun;156(6):617-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Regressive liver adenomatosis following androgenic progestin therapy withdrawal: a case report with a 10-year follow-up and a molecular analysis.
  • On the contrary, their contribution to liver adenomatosis (LA) development is still a debatable issue.

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  • Hazardous Substances Data Bank. Lynestrenol .
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  • (PMID = 17535860.001).
  • [ISSN] 0804-4643
  • [Journal-full-title] European journal of endocrinology
  • [ISO-abbreviation] Eur. J. Endocrinol.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Contraceptives, Oral, Synthetic; 0 / Hepatocyte Nuclear Factor 1-alpha; 0 / Receptors, Androgen; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone; N2Z8ALG4U5 / Lynestrenol
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4. Kwon JE, Park YN: [Hepatic adenomatosis in glycogen storage disease]. Korean J Hepatol; 2008 Mar;14(1):108-12
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  • [Title] [Hepatic adenomatosis in glycogen storage disease].

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  • (PMID = 18367864.001).
  • [ISSN] 1738-222X
  • [Journal-full-title] The Korean journal of hepatology
  • [ISO-abbreviation] Korean J Hepatol
  • [Language] kor
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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5. Beaton MD, Taylor B, Driman D, Ainsworth P, Adams PC: Colonic interposition in a woman with attenuated familial adenomatosis polyposis: does the location of the colon affect polyp formation? Can J Gastroenterol; 2008 Jul;22(7):634-6
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  • [Title] Colonic interposition in a woman with attenuated familial adenomatosis polyposis: does the location of the colon affect polyp formation?
  • Attenuated familial adenomatous polyposis (AFAP) is a rare but well-established cause of colorectal carcinoma and multiple polyps.
  • While she had developed adenomatous polyps in her native cecum, there was no evidence of polyps or cancer in the segment of large intestine interposed between her upper esophagus and stomach.
  • [MeSH-major] Adenomatous Polyposis Coli / pathology. Colonic Polyps / pathology

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  • (PMID = 18629394.001).
  • [ISSN] 0835-7900
  • [Journal-full-title] Canadian journal of gastroenterology = Journal canadien de gastroenterologie
  • [ISO-abbreviation] Can. J. Gastroenterol.
  • [Language] eng
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  • [Other-IDs] NLM/ PMC2661270
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6. Sa Cunha A, Blanc JF, Lazaro E, Mellottee L, Le Bail B, Zucman-Rossi J, Balabaud C, Bioulac-Sage P: Inflammatory syndrome with liver adenomatosis: the beneficial effects of surgical management. Gut; 2007 Feb;56(2):307-9
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  • [Title] Inflammatory syndrome with liver adenomatosis: the beneficial effects of surgical management.

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  • (PMID = 17303609.001).
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  • [Journal-full-title] Gut
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7. Barthelmes L, Tait IS: Liver cell adenoma and liver cell adenomatosis. HPB (Oxford); 2005;7(3):186-96

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Liver cell adenoma and liver cell adenomatosis.
  • During the last three decades liver cell adenoma and liver cell adenomatosis have emerged as new clinical entities in hepato-logical practice due to the widespread use of oral contraceptives and increased imaging of the liver.
  • In liver cell adenomatosis, the association with oral contraceptive use is not as high as in solitary liver cell adenomas.
  • Liver transplantation is the last resort in case of substantive concern about malignant transformation or for large, painful adenomas in liver cell adenomatosis after treatment attempts by liver resection.

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  • [CommentIn] HPB (Oxford). 2006;8(1):71-2 [18333245.001]
  • (PMID = 18333188.001).
  • [ISSN] 1365-182X
  • [Journal-full-title] HPB : the official journal of the International Hepato Pancreato Biliary Association
  • [ISO-abbreviation] HPB (Oxford)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2023950
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8. Elander N, Zhou J, Ungerbäck J, Dimberg J, Söderkvist P: Association between adenomatosis polyposis coli functional status and microsomal prostaglandin E synthase-1 expression in colorectal cancer. Mol Carcinog; 2009 May;48(5):401-7
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  • [Title] Association between adenomatosis polyposis coli functional status and microsomal prostaglandin E synthase-1 expression in colorectal cancer.
  • Previous reports reveal that defects of the tumor suppressor adenomatosis polyposis coli (APC) contribute to COX-2 upregulation in colon tumor cells.

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  • (PMID = 19035518.001).
  • [ISSN] 1098-2744
  • [Journal-full-title] Molecular carcinogenesis
  • [ISO-abbreviation] Mol. Carcinog.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / RNA, Messenger; 0 / RNA, Small Interfering; EC 5.3.- / Intramolecular Oxidoreductases; EC 5.3.99.3 / prostaglandin-E synthase
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9. Wijn MA, Keller JJ, Brand HS: [Oral and maxillofacial manifestations of familial adenomatosis polyposis. Gardner's syndrome]. Ned Tijdschr Tandheelkd; 2005 Sep;112(9):340-4
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  • [Title] [Oral and maxillofacial manifestations of familial adenomatosis polyposis. Gardner's syndrome].
  • [Transliterated title] Orale en maxillofaciale afwijkingen bij familiaire adenomateuze polyposis. Het syndroom van Gardner.
  • Patients suffering from familial adenomatosis polyposis develop multiple pre-malignant gastrointestinal polyps and are at high risk of developing colon cancer.
  • The combination of extra-intestinal manifestations and familial adenomatosis polyposis is named Gardner's syndrome.
  • [MeSH-minor] Abnormalities, Multiple / genetics. Humans. Intestinal Polyps / epidemiology. Intestinal Polyps / genetics. Intestinal Polyps / pathology. Tooth, Impacted / epidemiology. Tooth, Impacted / etiology. Tooth, Impacted / genetics. Tooth, Supernumerary / epidemiology. Tooth, Supernumerary / etiology. Tooth, Supernumerary / genetics

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  • (PMID = 16184913.001).
  • [ISSN] 0028-2200
  • [Journal-full-title] Nederlands tijdschrift voor tandheelkunde
  • [ISO-abbreviation] Ned Tijdschr Tandheelkd
  • [Language] dut
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 30
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10. Peranteau WH, Bathaii SM, Pawel B, Hardy O, Alavi A, Stanley CA, Adzick NS: Multiple ectopic lesions of focal islet adenomatosis identified by positron emission tomography scan in an infant with congenital hyperinsulinism. J Pediatr Surg; 2007 Jan;42(1):188-92
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  • [Title] Multiple ectopic lesions of focal islet adenomatosis identified by positron emission tomography scan in an infant with congenital hyperinsulinism.


11. Kim YT, Park JY, Jeon YK, Park SJ, Song JY, Kang CH, Sung SW, Kim JH: Aberrant promoter CpG island hypermethylation of the adenomatosis polyposis coli gene can serve as a good prognostic factor by affecting lymph node metastasis in squamous cell carcinoma of the esophagus. Dis Esophagus; 2009;22(2):143-50
MedlinePlus Health Information. consumer health - Esophageal Cancer.

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  • [Title] Aberrant promoter CpG island hypermethylation of the adenomatosis polyposis coli gene can serve as a good prognostic factor by affecting lymph node metastasis in squamous cell carcinoma of the esophagus.
  • CpG island hypermethylations were observed in 10% for p16, 34% for RARbetaP2, 46% for adenomatosis polyposis coli (APC), 14% for RASSF1A, 84% for FHIT, and 8% for hMLH1.

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  • (PMID = 18847451.001).
  • [ISSN] 1442-2050
  • [Journal-full-title] Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
  • [ISO-abbreviation] Dis. Esophagus
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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12. Marín Hernández C, Robles Campos R, López Conesa A, Parrilla P: [Multiple liver adenomatosis treated with surgical resection and radiofrequency]. Cir Esp; 2010 Nov;88(5):337-8
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  • [Title] [Multiple liver adenomatosis treated with surgical resection and radiofrequency].
  • [Transliterated title] Adenomatosis hepática múltiple tratada con resección quirúrgica y radiofrecuencia.

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  • (PMID = 20206344.001).
  • [ISSN] 1578-147X
  • [Journal-full-title] Cirugía española
  • [ISO-abbreviation] Cir Esp
  • [Language] spa
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Spain
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13. Brunt EM, Wolverson MK, Di Bisceglie AM: Benign hepatocellular tumors (adenomatosis) in nonalcoholic steatohepatitis: a case report. Semin Liver Dis; 2005;25(2):230-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign hepatocellular tumors (adenomatosis) in nonalcoholic steatohepatitis: a case report.

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  • (PMID = 15918151.001).
  • [ISSN] 0272-8087
  • [Journal-full-title] Seminars in liver disease
  • [ISO-abbreviation] Semin. Liver Dis.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34
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14. Lepistö A, Kiviluoto T, Halttunen J, Järvinen HJ: Surveillance and treatment of duodenal adenomatosis in familial adenomatous polyposis. Endoscopy; 2009 Jun;41(6):504-9
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  • [Title] Surveillance and treatment of duodenal adenomatosis in familial adenomatous polyposis.
  • BACKGROUND AND STUDY AIMS: Patients with familial adenomatous polyposis (FAP) are at increased risk for duodenal cancer whereas colorectal cancer is largely prevented by prophylactic colectomy.
  • We analyzed the results of endoscopic surveillance and different treatment modalities of duodenal adenomatosis in patients with FAP.
  • The cumulative incidences of duodenal adenomatosis and severe dysplasia and cancer were calculated using Kaplan-Meier analysis.
  • RESULTS: By the age of 60 years, the cumulative incidence was 80% for any adenomatosis and 23% for severe dysplasia or cancer.
  • CONCLUSIONS: The high incidence of severe dysplasia and cancer in duodenal polyps suggests that endoscopic surveillance is essential.
  • High-risk patients with Spigelman IV adenomatosis or adenomas with persisting severe dysplasia should undergo surgery with pylorus-preserving pancreaticoduodenectomy before invasive cancer develops.
  • [MeSH-major] Adenomatous Polyposis Coli / complications. Duodenal Neoplasms / diagnosis. Duodenal Neoplasms / epidemiology. Intestinal Polyps / complications


15. Kok NF, Terkivatan T, Ijzermans JN: Regarding 'Liver cell adenoma and liver cell adenomatosis' by Ludger Barthelmes and Iain S. Tait. HPB (Oxford); 2006;8(1):71-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Regarding 'Liver cell adenoma and liver cell adenomatosis' by Ludger Barthelmes and Iain S. Tait.

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  • [Cites] Am J Surg Pathol. 2005 Dec;29(12):1600-8 [16327432.001]
  • [Cites] Arch Surg. 2001 Sep;136(9):1033-8 [11529826.001]
  • [Cites] World J Gastroenterol. 2005 Sep 28;11(36):5691-5 [16237767.001]
  • [CommentOn] HPB (Oxford). 2005;7(3):186-96 [18333188.001]
  • (PMID = 18333245.001).
  • [ISSN] 1365-182X
  • [Journal-full-title] HPB : the official journal of the International Hepato Pancreato Biliary Association
  • [ISO-abbreviation] HPB (Oxford)
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2131360
  •  go-up   go-down


16. Kobayashi S, Sakaguchi H, Takatsuka M, Suekane T, Iwai S, Morikawa H, Enomoto M, Tamori A, Kawada N: Two cases of hepatocellular adenomatosis treated with transcatheter arterial embolization. Hepatol Int; 2009 Jun;3(2):416-20

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  • [Title] Two cases of hepatocellular adenomatosis treated with transcatheter arterial embolization.
  • Surgical resection is considered to be the best choice of treatment, when adenomas are increasing in size, while resection is difficult to perform when multiple adenomas develop throughout the liver.
  • Here, we report two cases of multiple hepatocellular adenomatosis.
  • These cases suggest that TAE is an effective treatment of hepatocellular adenomatosis.

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  • [Cites] Liver Transpl Surg. 1998 Sep;4(5):388-98 [9724476.001]
  • [Cites] Ann Surg. 2000 Jan;231(1):74-81 [10636105.001]
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  • (PMID = 19669369.001).
  • [ISSN] 1936-0533
  • [Journal-full-title] Hepatology international
  • [ISO-abbreviation] Hepatol Int
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2716763
  •  go-up   go-down


17. El Idrissi F, Fadli A: [Erosive adenomatosis of the nipple]. J Gynecol Obstet Biol Reprod (Paris); 2005 Dec;34(8):813-4
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  • [Title] [Erosive adenomatosis of the nipple].
  • The histological analysis led to the diagnosis of erosive nipple adenomatosis.
  • Erosive adenomatosis of the nipple is a benign tumor which developing within the lactic nipple.
  • Erosive adenomatosis of the nipple is very rare and should be suspected in patients with nipple erosions or a nipple tumor.

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  • (PMID = 16319774.001).
  • [ISSN] 0368-2315
  • [Journal-full-title] Journal de gynécologie, obstétrique et biologie de la reproduction
  • [ISO-abbreviation] J Gynecol Obstet Biol Reprod (Paris)
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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18. Fujita S, Mekeel KL, Fujikawa T, Kim RD, Foley DP, Hemming AW, Howard RJ, Reed AI, Dixon LR: Liver-occupying focal nodular hyperplasia and adenomatosis associated with intrahepatic portal vein agenesis requiring orthotopic liver transplantation. Transplantation; 2006 Feb 15;81(3):490-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Liver-occupying focal nodular hyperplasia and adenomatosis associated with intrahepatic portal vein agenesis requiring orthotopic liver transplantation.


19. Ku BS, Kwon OE, Kim DC, Song KH, Lee CW, Kim KH: A case of erosive adenomatosis of nipple treated with total excision using purse-string suture. Dermatol Surg; 2006 Aug;32(8):1093-6
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  • [Title] A case of erosive adenomatosis of nipple treated with total excision using purse-string suture.

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  • [CommentIn] Dermatol Surg. 2007 Aug;33(8):1001 [17661951.001]
  • (PMID = 16918575.001).
  • [ISSN] 1076-0512
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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20. Berkhout M, Roelofs HM, te Morsche RH, Dekker E, van Krieken JH, Nagengast FM, Peters WH: Detoxification enzyme polymorphisms are not involved in duodenal adenomatosis in familial adenomatous polyposis. Br J Surg; 2008 Apr;95(4):499-505
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Detoxification enzyme polymorphisms are not involved in duodenal adenomatosis in familial adenomatous polyposis.
  • BACKGROUND: Patients with familial adenomatous polyposis (FAP) are at high risk of developing duodenal adenomas and carcinomas.
  • Besides germline mutations in the adenomatous polyposis coli (APC) gene, additional factors may influence the age of onset and number of duodenal adenomas.
  • The polymorphisms investigated had no predictive value for the severity of duodenal adenomatosis in patients with FAP.
  • CONCLUSION: Although the variant genotypes of UGT1A3 were less common in patients with FAP than in those without, this did not modulate the severity of duodenal adenomatosis.
  • [MeSH-major] Adenomatous Polyposis Coli / enzymology. Duodenal Neoplasms / enzymology. Genes, APC. Glucuronosyltransferase / genetics. Glutathione Transferase / genetics. Polymorphism, Genetic / genetics


21. Laumonier H, Rullier A, Saric J, Balabaud C, Bioulac-Sage P: Unexpected discovery of 2 cases of hepatocyte nuclear factor 1alpha-mutated infracentimetic adenomatosis. World J Gastroenterol; 2008 Aug 14;14(30):4830-3
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  • [Title] Unexpected discovery of 2 cases of hepatocyte nuclear factor 1alpha-mutated infracentimetic adenomatosis.
  • We present 2 cases of hepatocyte nuclear factor 1alpha (HNF1alpha)-mutated adenomatosis, discovered for reasons unrelated to this disease, and identified using immunohistochemical methods.
  • These new tools may further our understanding of the link between adenomas/adenomatosis subtypes and their complications, and their association with other abnormalities.

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  • [Cites] Am J Surg Pathol. 2001 Oct;25(10):1322-5 [11688469.001]
  • [Cites] J Hepatol. 2008 Jan;48(1):163-70 [17997499.001]
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  • [Cites] J Hepatol. 2003 Jul;39(1):77-85 [12821047.001]
  • [Cites] Gastroenterology. 2003 Nov;125(5):1470-5 [14598263.001]
  • [Cites] J Clin Endocrinol Metab. 2004 Mar;89(3):1476-80 [15001650.001]
  • [Cites] Gastroenterology. 2004 May;126(5):1323-9 [15131793.001]
  • [Cites] N Engl J Med. 1978 Aug 3;299(5):239-41 [207987.001]
  • [Cites] Gastroenterology. 1985 Nov;89(5):1132-8 [2412930.001]
  • [Cites] Mod Pathol. 1989 Sep;2(5):456-62 [2813344.001]
  • [Cites] Liver Transpl Surg. 1998 Sep;4(5):388-98 [9724476.001]
  • [Cites] Gastroenterology. 2005 May;128(5):1211-8 [15887105.001]
  • [Cites] Semin Liver Dis. 2005;25(2):230-6 [15918151.001]
  • [Cites] Hepatology. 2006 Mar;43(3):515-24 [16496320.001]
  • [Cites] Nat Clin Pract Gastroenterol Hepatol. 2006 Sep;3(9):526-31; quiz (following 531) [16951669.001]
  • [Cites] J Hepatol. 2007 Mar;46(3):521-7 [17239484.001]
  • [Cites] Hepatology. 2007 Jul;46(1):140-6 [17596890.001]
  • [Cites] Hepatology. 2007 Sep;46(3):740-8 [17663417.001]
  • [Cites] Nat Genet. 2002 Oct;32(2):312-5 [12355088.001]
  • (PMID = 18720549.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P50 CA095817
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Hepatocyte Nuclear Factor 1-alpha
  • [Other-IDs] NLM/ PMC2739350
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22. Veteläinen R, Erdogan D, de Graaf W, ten Kate F, Jansen PL, Gouma DJ, van Gulik TM: Liver adenomatosis: re-evaluation of aetiology and management. Liver Int; 2008 Apr;28(4):499-508
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Liver adenomatosis: re-evaluation of aetiology and management.
  • BACKGROUND: Liver adenomatosis (LA) is a rare benign parenchymal liver disease with unknown aetiology.
  • CONCLUSION: Liver adenomatosis is a progressive, benign parenchymal disease mainly occurring in females.

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  • [CommentIn] Liver Int. 2009 Jan;29(1):142 [18828785.001]
  • (PMID = 18339077.001).
  • [ISSN] 1478-3231
  • [Journal-full-title] Liver international : official journal of the International Association for the Study of the Liver
  • [ISO-abbreviation] Liver Int.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 57
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23. Lerario AM, Brito LP, Mariani BM, Fragoso MC, Machado MA, Teixeira R: A missense TCF1 mutation in a patient with mody-3 and liver adenomatosis. Clinics (Sao Paulo); 2010;65(10):1059-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A missense TCF1 mutation in a patient with mody-3 and liver adenomatosis.

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  • [Cites] J Clin Endocrinol Metab. 2004 Mar;89(3):1476-80 [15001650.001]
  • [Cites] N Engl J Med. 1978 Aug 3;299(5):239-41 [207987.001]
  • [Cites] Gastroenterology. 1985 Nov;89(5):1132-8 [2412930.001]
  • [Cites] Hum Mutat. 2006 Sep;27(9):854-69 [16917892.001]
  • [Cites] Gastroenterology. 2003 Nov;125(5):1470-5 [14598263.001]
  • [Cites] Radiology. 2000 Aug;216(2):395-402 [10924560.001]
  • [Cites] N Engl J Med. 2001 Sep 27;345(13):971-80 [11575290.001]
  • [Cites] Nat Genet. 2002 Oct;32(2):312-5 [12355088.001]
  • [Cites] Diabetologia. 2003 May;46(5):721-7 [12712243.001]
  • [Cites] Ann Surg. 2000 Jan;231(1):74-81 [10636105.001]
  • (PMID = 21120312.001).
  • [ISSN] 1980-5322
  • [Journal-full-title] Clinics (São Paulo, Brazil)
  • [ISO-abbreviation] Clinics (Sao Paulo)
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Brazil
  • [Chemical-registry-number] 0 / HNF1A protein, human; 0 / Hepatocyte Nuclear Factor 1-alpha
  • [Other-IDs] NLM/ PMC2972616
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24. Müller MW, Dahmen R, Köninger J, Michalski CW, Hinz U, Hartel M, Kadmon M, Kleeff J, Büchler MW, Friess H: Is there an advantage in performing a pancreas-preserving total duodenectomy in duodenal adenomatosis? Am J Surg; 2008 Jun;195(6):741-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Is there an advantage in performing a pancreas-preserving total duodenectomy in duodenal adenomatosis?
  • BACKGROUND: Duodenal adenomatosis is a premalignant condition often not treatable by local resection or endoscopy.
  • Since the introduction of pancreas-preserving total duodenectomy (PPTD), the question has arisen whether a pp-Whipple resection is still needed to treat duodenal adenomatosis.
  • PATIENTS AND METHODS: In a 5-year period 23 PPTDs were performed for duodenal adenomatosis.
  • CONCLUSIONS: PPTD is a safe surgical procedure for duodenal adenomatosis that avoids pancreatic head resection, provides high quality of life, and shows advantages over the pp-Whipple procedure.

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  • (PMID = 18436175.001).
  • [ISSN] 1879-1883
  • [Journal-full-title] American journal of surgery
  • [ISO-abbreviation] Am. J. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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25. Chen R, Axell L, Klein C: Attenuated familial adenomatosis polyposis. J Clin Oncol; 2007 Feb 20;25(6):724-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Attenuated familial adenomatosis polyposis.
  • [MeSH-major] Adenomatous Polyposis Coli / diagnosis. Adenomatous Polyposis Coli / genetics. Genes, APC. Genetic Predisposition to Disease

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  • (PMID = 17308276.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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26. Giovanoli O, Heim M, Terracciano L, Bongartz G, Ledermann HP: MRI of hepatic adenomatosis: initial observations with gadoxetic acid contrast agent in three patients. AJR Am J Roentgenol; 2008 May;190(5):W290-3
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  • [Title] MRI of hepatic adenomatosis: initial observations with gadoxetic acid contrast agent in three patients.
  • OBJECTIVE: The purpose of our study was to describe the MR signal characteristics of histologically proven liver adenomatosis in three patients using gadoxetic acid, a newly developed liver-specific MR contrast agent.

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  • (PMID = 18430814.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 0 / gadolinium ethoxybenzyl DTPA; K2I13DR72L / Gadolinium DTPA
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27. Beytut E, Sözmen M, Ergínsoy S: Immunohistochemical detection of pulmonary surfactant proteins and retroviral antigens in the lungs of sheep with pulmonary adenomatosis. J Comp Pathol; 2009 Jan;140(1):43-53
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  • [Title] Immunohistochemical detection of pulmonary surfactant proteins and retroviral antigens in the lungs of sheep with pulmonary adenomatosis.
  • The lungs and mediastinal and bronchial lymph nodes from 26 sheep with ovine pulmonary adenomatosis (OPA) were examined.
  • [MeSH-major] Antigens, Viral / metabolism. Lung / metabolism. Pulmonary Adenomatosis, Ovine / metabolism. Pulmonary Surfactant-Associated Protein A / metabolism. Pulmonary Surfactant-Associated Protein B / metabolism. Pulmonary Surfactant-Associated Protein C / metabolism. Retroviridae / immunology

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  • (PMID = 19081577.001).
  • [ISSN] 0021-9975
  • [Journal-full-title] Journal of comparative pathology
  • [ISO-abbreviation] J. Comp. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD3; 0 / Antigens, Viral; 0 / Proliferating Cell Nuclear Antigen; 0 / Pulmonary Surfactant-Associated Protein A; 0 / Pulmonary Surfactant-Associated Protein B; 0 / Pulmonary Surfactant-Associated Protein C; 9060-09-7 / Uteroglobin
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28. Bambha K, Nagorney D, Sanderson S, Gores GJ: Hepatic adenomatosis in a young woman with glucose intolerance. Nat Clin Pract Gastroenterol Hepatol; 2006 Sep;3(9):526-31; quiz (following 531)
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  • [Title] Hepatic adenomatosis in a young woman with glucose intolerance.
  • DIAGNOSIS: Hepatic adenomatosis.

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  • (PMID = 16951669.001).
  • [ISSN] 1743-4378
  • [Journal-full-title] Nature clinical practice. Gastroenterology & hepatology
  • [ISO-abbreviation] Nat Clin Pract Gastroenterol Hepatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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29. Dekker E, Boparai KS, Poley JW, Mathus-Vliegen EM, Offerhaus GJ, Kuipers EJ, Fockens P, Dees J: High resolution endoscopy and the additional value of chromoendoscopy in the evaluation of duodenal adenomatosis in patients with familial adenomatous polyposis. Endoscopy; 2009 Aug;41(8):666-9
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  • [Title] High resolution endoscopy and the additional value of chromoendoscopy in the evaluation of duodenal adenomatosis in patients with familial adenomatous polyposis.
  • BACKGROUND AND STUDY AIM: Duodenal polyposis occurs in approximately 90 % of patients with familial adenomatous polyposis (FAP) and 5 % - 10 % develop duodenal cancer.
  • Novel imaging techniques may improve evaluation of duodenal polyposis using the Spigelman classification.
  • We aimed to analyze the value of high resolution endoscopy (HRE) and the additional value of chromoendoscopy in the evaluation of duodenal polyposis in FAP.
  • After number and size of adenomas had been scored, indigo carmine 0.5 % was sprayed onto the mucosa, polyps were scored again and biopsies taken from the larger lesions.
  • Therefore, a combination of forward-viewing HRE and chromoendoscopy with side-viewing endoscopy for the periampullary region seems useful for surveillance of duodenal adenomatosis in FAP.
  • [MeSH-major] Adenoma / diagnosis. Adenomatous Polyposis Coli / complications. Duodenal Neoplasms / diagnosis. Duodenoscopy / methods


30. Gorbacheva OS, Popova LP, Ivanov SV, Iakovleva MV, Bondarev VP: [Cytological classification of nontoxic nodular goiter]. Klin Lab Diagn; 2008 Jan;(1):37-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • By comparing the cytological and histological data on thyroid nodular lesions in 715 patients, the authors have arrived at the conclusion that with a cytological response of colloidal goiter and colloidal goiter with adenomatosis, the cancer detection rate is not greater than 4%.
  • With a cytological response of adenomatosis with atypia and follicular tumor, a malignancy occurs in 9 to 13%.
  • It is recommended that cytological data should be grouped by the type of a morphological classification of thyroid nodular diseases: colloidal goiter (with regression, proliferation, adenomatosis, cystic cavity); tumors (adenomatosis with atypia, follicular tumor); cancer.

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  • (PMID = 18320618.001).
  • [ISSN] 0869-2084
  • [Journal-full-title] Klinicheskaia laboratornaia diagnostika
  • [ISO-abbreviation] Klin. Lab. Diagn.
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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31. Babaoglu K, Binnetoglu FK, Aydoğan A, Altun G, Gürbüz Y, Inan N, Corapçioğlu F: Hepatic adenomatosis in a 7-year-old child treated earlier with a Fontan procedure. Pediatr Cardiol; 2010 Aug;31(6):861-4
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  • [Title] Hepatic adenomatosis in a 7-year-old child treated earlier with a Fontan procedure.
  • However, hepatic adenoma and hepatic adenomatosis (HA) are not well-known pathologies during the course of cardiac hepatopathy.
  • Hepatic adenomatosis was diagnosed on the basis of magnetic resonance imaging (MRI) and MRI-guided liver biopsy.
  • To the best of the authors' knowledge, this case involved the youngest patient with hepatocellular adenomatosis documented in the literature.

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  • (PMID = 20204345.001).
  • [ISSN] 1432-1971
  • [Journal-full-title] Pediatric cardiology
  • [ISO-abbreviation] Pediatr Cardiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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32. Hagiwara S, Takagi H, Kanda D, Sohara N, Kakizaki S, Katakai K, Yoshinaga T, Higuchi T, Nomoto K, Kuwano H, Mori M: Hepatic adenomatosis associated with hormone replacement therapy and hemosiderosis: a case report. World J Gastroenterol; 2006 Jan 28;12(4):652-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hepatic adenomatosis associated with hormone replacement therapy and hemosiderosis: a case report.
  • We have reported a case of hepatic adenomatosis associated with hormone replacement therapy (estrogen and progesterone) and hemosiderosis caused by excessive blood transfusion for the treatment of chronic myeloid leukemia.
  • Histopathological examination of the surgical specimen showed hepatic adenomatosis with hemosiderosis.
  • Both hormone replacement therapy and iron overload could be the cause of hepatic adenomatosis.

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  • [Cites] Postgrad Med J. 2000 Feb;76(892):100-2 [10644389.001]
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  • (PMID = 16489686.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC4066105
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33. Ivanov SV, Zhabin SN, Gorbacheva OS, Barsukov VS, Denisova EIu: [Multifactor analysis of nodular goiter by the method of artificial neural network]. Klin Med (Mosk); 2008;86(4):49-50

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Study of 297 patients with preparative methods of nontoxic nodular goiter and cytological diagnose "adenomatosis" with the use of artificial neural network (ANN) were analyzed.
  • Painless elastic nodules with sonographically iso- o hyperechogenic structure, with clear outline and cytologically determined adenomatosis in combination with colloid can be interpreted as benign lesion of thyroid gland.

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  • (PMID = 18494287.001).
  • [ISSN] 0023-2149
  • [Journal-full-title] Klinicheskaia meditsina
  • [ISO-abbreviation] Klin Med (Mosk)
  • [Language] rus
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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34. Gallagher MC, Phillips RK, Bulow S: Surveillance and management of upper gastrointestinal disease in Familial Adenomatous Polyposis. Fam Cancer; 2006;5(3):263-73
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surveillance and management of upper gastrointestinal disease in Familial Adenomatous Polyposis.
  • Almost all patients affected by Familial Adenomatous polyposis (FAP) will develop foregut as well as hindgut polyps, and following prophylactic colectomy duodenal cancer constitutes one of the leading causes of death in screened populations.
  • Management of the upper gastrointestinal cancer risk is one of the greatest challenges facing clinicians involved in the care of Polyposis families, and with improved survival following prophylactic colectomy, the burden of foregut disease (particularly duodenal adenomatosis) will increase.
  • Until recently, the value of upper gastrointestinal surveillance in FAP populations has been contentious, but with improved understanding of the natural history coupled with developments in surgery, interventional endoscopy and medical therapy, treatment algorithms for duodenal adenomatosis in FAP are becoming clearer.
  • [MeSH-major] Adenomatous Polyposis Coli / complications. Gastrointestinal Neoplasms / diagnosis. Gastrointestinal Neoplasms / therapy. Upper Gastrointestinal Tract / pathology

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  • (PMID = 16998672.001).
  • [ISSN] 1389-9600
  • [Journal-full-title] Familial cancer
  • [ISO-abbreviation] Fam. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 126
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35. Arvind N, Duraimurugan D, Rajkumar JS: Hepatic adenomatosis--a rare double complication of multiple adenoma rupture and malignant transformation. Indian J Gastroenterol; 2006 Jul-Aug;25(4):209-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hepatic adenomatosis--a rare double complication of multiple adenoma rupture and malignant transformation.
  • Hepatic adenomatosis (HA) is a rare disorder that is susceptible to hemorrhagic complications and, rarely, to malignant transformation.

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  • (PMID = 16974041.001).
  • [ISSN] 0254-8860
  • [Journal-full-title] Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology
  • [ISO-abbreviation] Indian J Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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36. Wellen JR, Anderson CD, Doyle M, Shenoy S, Nadler M, Turmelle Y, Shepherd R, Chapman WC, Lowell JA: The role of liver transplantation for hepatic adenomatosis in the pediatric population: case report and review of the literature. Pediatr Transplant; 2010 May;14(3):E16-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The role of liver transplantation for hepatic adenomatosis in the pediatric population: case report and review of the literature.
  • These tumors are often solitary but can also be multiple in which case this is referred to as hepatic adenomatosis (HA).

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  • (PMID = 19490491.001).
  • [ISSN] 1399-3046
  • [Journal-full-title] Pediatric transplantation
  • [ISO-abbreviation] Pediatr Transplant
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Denmark
  • [Number-of-references] 12
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37. Watkins J, Balabaud C, Bioulac-Sage P, Sharma D, Dhillon A: Hepatocellular adenoma in advanced-stage fatty liver disease. Eur J Gastroenterol Hepatol; 2009 Aug;21(8):932-6
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  • Hepatocellular adenomas are defined as benign hepatocellular neoplasms occurring in otherwise near normal liver and adenomatosis as 10 or more such lesions.
  • We present a case of a 45-year-old man with radiological adenomatosis, histologically confirmed with resection of one lesion, arising within advanced-stage nonalcoholic fatty liver disease (nearly cirrhotic).
  • Hepatocellular adenomas have recently been divided into four categories and the lesion in the present case had morphologic and immunohistochemical features of an inflammatory hepatocellular adenoma.

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  • (PMID = 19404203.001).
  • [ISSN] 1473-5687
  • [Journal-full-title] European journal of gastroenterology & hepatology
  • [ISO-abbreviation] Eur J Gastroenterol Hepatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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38. Ek ET, Ek EW, Moulton CA, Mackay S: Incidental discovery of massive hepatic adenomatosis. ANZ J Surg; 2005 Jan-Feb;75(1-2):90-1
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  • [Title] Incidental discovery of massive hepatic adenomatosis.

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  • (PMID = 15740530.001).
  • [ISSN] 1445-1433
  • [Journal-full-title] ANZ journal of surgery
  • [ISO-abbreviation] ANZ J Surg
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Australia
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39. Lewin M, Handra-Luca A, Arrivé L, Wendum D, Paradis V, Bridel E, Fléjou JF, Belghiti J, Tubiana JM, Vilgrain V: Liver adenomatosis: classification of MR imaging features and comparison with pathologic findings. Radiology; 2006 Nov;241(2):433-40
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  • [Title] Liver adenomatosis: classification of MR imaging features and comparison with pathologic findings.
  • PURPOSE: To retrospectively compare the clinical manifestation and magnetic resonance (MR) imaging features of liver adenomatosis with pathologic findings.
  • Twenty patients were classified on the basis of pathologic findings into three groups: those with a steatotic, those with a peliotic, and those with a mixed (steatotic and peliotic) form of liver adenomatosis.
  • CONCLUSION: There are three patterns of MR imaging features of liver adenomatosis that are associated with three pathologic forms (steatotic, peliotic, and mixed).

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  • (PMID = 16966481.001).
  • [ISSN] 0033-8419
  • [Journal-full-title] Radiology
  • [ISO-abbreviation] Radiology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Organometallic Compounds; 0 / gadoterate meglumine; 6HG8UB2MUY / Meglumine
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40. Jeannot E, Poussin K, Chiche L, Bacq Y, Sturm N, Scoazec JY, Buffet C, Van Nhieu JT, Bellanné-Chantelot C, de Toma C, Laurent-Puig P, Bioulac-Sage P, Zucman-Rossi J: Association of CYP1B1 germ line mutations with hepatocyte nuclear factor 1alpha-mutated hepatocellular adenoma. Cancer Res; 2007 Mar 15;67(6):2611-6
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  • In rare cases, HNF1alpha germ line mutations could also predispose to familial adenomatosis.
  • In addition, an E229K CYP1B1 mutation was found in a woman with a germ line HNF1alpha mutation in a familial adenomatosis context.
  • In this large family, all three patients with adenomatosis bore both HNF1 and CYP1B1 germ line mutations.
  • [MeSH-minor] Adolescent. Adult. Alleles. Aryl Hydrocarbon Hydroxylases. Child. Cytochrome P-450 CYP1B1. Female. Genetic Predisposition to Disease. Genotype. Humans. Middle Aged. Mutagenesis, Site-Directed. Pedigree

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  • (PMID = 17363580.001).
  • [ISSN] 0008-5472
  • [Journal-full-title] Cancer research
  • [ISO-abbreviation] Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Hepatocyte Nuclear Factor 1-alpha; 9035-51-2 / Cytochrome P-450 Enzyme System; EC 1.14.14.1 / Aryl Hydrocarbon Hydroxylases; EC 1.14.14.1 / CYP1B1 protein, human; EC 1.14.14.1 / Cytochrome P-450 CYP1B1
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41. Hardy OT, Hernandez-Pampaloni M, Saffer JR, Scheuermann JS, Ernst LM, Freifelder R, Zhuang H, MacMullen C, Becker S, Adzick NS, Divgi C, Alavi A, Stanley CA: Accuracy of [18F]fluorodopa positron emission tomography for diagnosing and localizing focal congenital hyperinsulinism. J Clin Endocrinol Metab; 2007 Dec;92(12):4706-11
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  • OBJECTIVES: Focal lesions in infants with congenital hyperinsulinism (HI) represent areas of adenomatosis that express a paternally derived ATP-sensitive potassium channel mutation due to embryonic loss of heterozygosity for the maternal 11p region.
  • The positive predictive value of [18F]DOPA in diagnosing focal adenomatosis was 100%, and the negative predictive value was 81%.
  • These results suggest that [18F]DOPA PET imaging provides a useful guide to surgical resection of focal adenomatosis and should be considered as a guide to surgery in all infants with congenital HI who have medically uncontrollable disease.
  • [MeSH-minor] Biopsy. Humans. Image Interpretation, Computer-Assisted. Infant. Infant, Newborn. Islets of Langerhans / pathology. Kidney / pathology. Multiple Endocrine Neoplasia / pathology. Multiple Endocrine Neoplasia / radionuclide imaging. Pancreatectomy. Pancreatic Neoplasms / pathology. Pancreatic Neoplasms / radionuclide imaging. Positron-Emission Tomography. Sample Size

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  • (PMID = 17895314.001).
  • [ISSN] 0021-972X
  • [Journal-full-title] The Journal of clinical endocrinology and metabolism
  • [ISO-abbreviation] J. Clin. Endocrinol. Metab.
  • [Language] eng
  • [Grant] United States / NCRR NIH HHS / RR / M01-RR-00240; United States / NIDDK NIH HHS / DK / R01-DK-56268; United States / NIDDK NIH HHS / DK / T32-DK63688
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 2C598205QX / fluorodopa F 18; 63-84-3 / Dihydroxyphenylalanine
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42. Pechenikova VA: [Cancer transformation of adenomyosis]. Arkh Patol; 2005 Jul-Aug;67(4):51-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Various forms of transformation (stages of AMCT morphogensis) in and outside of denomyosis (AM) foci are described (adenomatosis, invasive cancer, metastases).

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  • (PMID = 16209300.001).
  • [ISSN] 0004-1955
  • [Journal-full-title] Arkhiv patologii
  • [ISO-abbreviation] Arkh. Patol.
  • [Language] rus
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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43. Kaufmann C, Brechbühl M, Oevermann A, Müller S, Zimmer K, Schönmann M, Leroux C, Weibel D, Bertoni G: [Enzootic nasal adenocarcinoma in a dairy sheep flock]. Schweiz Arch Tierheilkd; 2008 Jun;150(6):297-302
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The significance of the disease in Switzerland is discussed, also in the context of lung adenomatosis.
  • [MeSH-major] Adenocarcinoma / veterinary. Jaagsiekte sheep retrovirus / isolation & purification. Nose Neoplasms / veterinary. Pulmonary Adenomatosis, Ovine / diagnosis. Sheep Diseases / diagnosis

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  • (PMID = 18605021.001).
  • [ISSN] 0036-7281
  • [Journal-full-title] Schweizer Archiv für Tierheilkunde
  • [ISO-abbreviation] Schweiz. Arch. Tierheilkd.
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Switzerland
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44. Moya Herráiz A, Torres-Quevedo R, Mir Pallardó J: [Liver transplantation in patients with benign hepatic lesions]. Cir Esp; 2008 Aug;84(2):60-6
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  • We present a review of the subject, commenting on the aspects that have been subsidiary to liver transplantation, of which are highlighted: adenomatosis, polycystosis and hepatic epithelioid haemangioendothelioma (although this process may be a low to intermediate malignant grade).

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  • (PMID = 18682182.001).
  • [ISSN] 0009-739X
  • [Journal-full-title] Cirugía española
  • [ISO-abbreviation] Cir Esp
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 73
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45. Luo JR, Liu XH, Yu QY, Zhang SQ, Zhou JH, Ma XE: [A specific PCR assay and a nested PCR assay for the screening of ovine pulmonary adenomatosis]. Bing Du Xue Bao; 2009 Mar;25(2):125-30
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  • [Title] [A specific PCR assay and a nested PCR assay for the screening of ovine pulmonary adenomatosis].
  • Ovine pulmonary adenomatosis (OPA) is a naturally occurring contagious lung tumor of sheep which was caused by an exogenous retrovirus of sheep, jaagsiekte retrovirus (JSRV).

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  • (PMID = 19678567.001).
  • [ISSN] 1000-8721
  • [Journal-full-title] Bing du xue bao = Chinese journal of virology
  • [ISO-abbreviation] Bing Du Xue Bao
  • [Language] CHI
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / DNA, Viral
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46. Woldemeskel M, Tibbo M: Pulmonary adenomatosis and maedi-visna in Ethiopian central highland sheep: a microscopic study. Trop Anim Health Prod; 2010 Jun;42(5):995-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pulmonary adenomatosis and maedi-visna in Ethiopian central highland sheep: a microscopic study.
  • Lesions compatible with sheep pulmonary adenomatosis (SPA; 8/35, 22.8%), and maedi-visna (MV; 9/35, 25.7%) were recorded only in sheep from the central highlands.
  • [MeSH-major] Pulmonary Adenomatosis, Ovine / epidemiology. Sheep Diseases / epidemiology. Visna / epidemiology. Visna-maedi virus / isolation & purification

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  • (PMID = 20024674.001).
  • [ISSN] 1573-7438
  • [Journal-full-title] Tropical animal health and production
  • [ISO-abbreviation] Trop Anim Health Prod
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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47. Peters WH, te Morsche RH, Roelofs HM, Mathus-Vliegen EM, Berkhout M, Nagengast FM: COX-2 polymorphisms in patients with familial adenomatous polyposis. Oncol Res; 2009;17(8):347-51
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  • [Title] COX-2 polymorphisms in patients with familial adenomatous polyposis.
  • We investigated whether functional genetic polymorphisms in COX-2 may have a risk-modifying effect on duodenal adenomatosis in patients with familial adenomatous polyposis (FAP).
  • The COX-2 genotypes showed no association with the severity of duodenal adenomatosis.
  • [MeSH-major] Adenomatous Polyposis Coli / enzymology. Adenomatous Polyposis Coli / genetics. Cyclooxygenase 2 / genetics. Genetic Predisposition to Disease. Polymorphism, Single Nucleotide

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  • (PMID = 19544971.001).
  • [ISSN] 0965-0407
  • [Journal-full-title] Oncology research
  • [ISO-abbreviation] Oncol. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] EC 1.14.99.1 / Cyclooxygenase 2
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48. Grazioli L, Bondioni MP, Faccioli N, Gambarini S, Tinti R, Schneider G, Kirchin M: Solid focal liver lesions: dynamic and late enhancement patterns with the dual phase contrast agent gadobenate dimeglumine. J Gastrointest Cancer; 2010 Dec;41(4):221-32
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  • IMAGING FINDINGS: Unenhanced T2- and T1-weighted, dynamic T1-weighted (arterial, portal-venous, and equilibrium) and late phase (1-3 h) Gd-BOPTA-enhanced MR imaging of different focal liver lesions (nodular regenerative hyperplasia, hepatic adenoma, liver adenomatosis, hepatocellular carcinoma, peripheral cholangiocarcinoma, hypervascular metastases, and hypovascular metastases) are shown.

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  • (PMID = 20405242.001).
  • [ISSN] 1941-6636
  • [Journal-full-title] Journal of gastrointestinal cancer
  • [ISO-abbreviation] J Gastrointest Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Organometallic Compounds; 15G12L5X8K / gadobenic acid; 6HG8UB2MUY / Meglumine
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49. Shemerovskiĭ KA: [Constipation--a risk factor for colorectal cancer]. Klin Med (Mosk); 2005;83(12):60-4
MedlinePlus Health Information. consumer health - Constipation.

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  • The morphological signs of large bowel pre-cancer (dysplasia, adenomatosis, polyposis) seem to be secondary to the primary functional disorder of the circadian rhythm.
  • [MeSH-minor] Adenoma / epidemiology. Adenoma / etiology. Circadian Rhythm. Colonic Polyps / epidemiology. Colonic Polyps / etiology. Gastrointestinal Diseases / epidemiology. Humans. Precancerous Conditions / epidemiology. Precancerous Conditions / etiology. Quality of Life. Risk Factors. Russia / epidemiology

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  • (PMID = 16502728.001).
  • [ISSN] 0023-2149
  • [Journal-full-title] Klinicheskaia meditsina
  • [ISO-abbreviation] Klin Med (Mosk)
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Russia (Federation)
  • [Number-of-references] 25
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50. De Ferro SM, Lage P, Suspiro A, Fidalgo P, Fragoso S, Baltazar C, Vitoriano I, Rodrigues P, Albuquerque C, Leitão CN: [MYH associated polyposis: severe phenotype in the homozygosity for the 1103delC mutation]. Acta Med Port; 2007 May-Jun;20(3):243-7
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  • [Title] [MYH associated polyposis: severe phenotype in the homozygosity for the 1103delC mutation].
  • MYH-associated polyposis (MAP) is an autosomal recessive disease associated with multiple colonic adenomas and colorectal cancer.
  • Her sister aged 24 had 20 colonic adenomas and a severe Spigelman's III duodenal adenomatosis.
  • [MeSH-major] Adenomatous Polyposis Coli / genetics. DNA Glycosylases / genetics. Mutation

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  • (PMID = 17868535.001).
  • [ISSN] 1646-0758
  • [Journal-full-title] Acta médica portuguesa
  • [ISO-abbreviation] Acta Med Port
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Portugal
  • [Chemical-registry-number] EC 3.2.2.- / DNA Glycosylases; EC 3.2.2.- / mutY adenine glycosylase
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51. Haase M, Willenberg HS: Adrenal cortical tumors and multiple endocrine neoplasia-related syndromes. Minerva Endocrinol; 2009 Jun;34(2):123-35
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  • [Title] Adrenal cortical tumors and multiple endocrine neoplasia-related syndromes.
  • These syndromes and diseases include the Carney complex, the McCune-Albright syndrome, multiple endocrine neoplasia type 1, familial adenomatosis coli, congenital adrenal hyperplasia, familial forms of primary aldosteronism, the Beckwith-Wiedemann syndrome, and the Li-Fraumeni syndrome.
  • [MeSH-major] Adrenal Cortex Neoplasms / genetics. Multiple Endocrine Neoplasia / genetics. Mutation
  • [MeSH-minor] Adenomatous Polyposis Coli / genetics. Adrenal Hyperplasia, Congenital / genetics. Beckwith-Wiedemann Syndrome / genetics. Fibrous Dysplasia, Polyostotic / genetics. Heart Neoplasms / genetics. Humans. Hyperaldosteronism / genetics. Li-Fraumeni Syndrome / genetics. Multiple Endocrine Neoplasia Type 1 / genetics. Myxoma / genetics. Pigmentation Disorders / genetics

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  • (PMID = 19471237.001).
  • [ISSN] 0391-1977
  • [Journal-full-title] Minerva endocrinologica
  • [ISO-abbreviation] Minerva Endocrinol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Italy
  • [Number-of-references] 100
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52. Madani M, Madani F: Gardner's syndrome presenting with dental complaints. Arch Iran Med; 2007 Oct;10(4):535-9
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  • There are three distinctive features associated with this syndrome: familial intestinal polyposis or adenomatosis, surface tumors of hard tissues particularly osteoma in the skull, maxillae, and mandible, and finally surface tumors of the soft tissue.
  • The intestinal polyps have a 100% risk of undergoing malignant transformation if not treated.
  • In this article an 18-year-old male patient with previously undiagnosed Gardner's syndrome who presented for removal of multiple impacted and unerupted teeth is reported to illustrate the importance of early detection and proper referral.

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  • (PMID = 17903064.001).
  • [ISSN] 1029-2977
  • [Journal-full-title] Archives of Iranian medicine
  • [ISO-abbreviation] Arch Iran Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Iran
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53. Langers AM, De Vos tot Nederveen Cappel WH, Veenendaal RA, Bonsing BA, Hardwick JC, Vasen HF: Double balloon endoscopy for detection of small-bowel adenomas in familial adenomatous polyposis after pancreaticoduodenectomy according to Whipple. Endoscopy; 2008 Sep;40(9):773-4
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  • [Title] Double balloon endoscopy for detection of small-bowel adenomas in familial adenomatous polyposis after pancreaticoduodenectomy according to Whipple.
  • Patients with familial adenomatous polyposis (FAP) have a 5%-10% lifetime risk of developing duodenal cancer.
  • In severe duodenal polyposis, pancreaticoduodenectomy according to Whipple has been considered the only way to cure duodenal polyposis.
  • However, polyps recur even after surgery.
  • We describe a patient with severe adenomatosis of the small bowel in the afferent loop of a Roux-en-Y anastomosis after a Whipple procedure, detected by double balloon endoscopy (DBE).
  • [MeSH-major] Adenoma / diagnosis. Adenoma / surgery. Adenomatous Polyposis Coli / complications. Duodenal Neoplasms / diagnosis. Duodenal Neoplasms / surgery. Endoscopy / methods
  • [MeSH-minor] Anastomosis, Roux-en-Y. Catheterization. Cholangiopancreatography, Endoscopic Retrograde. Duodenal Diseases / surgery. Duodenoscopy. Humans. Intestinal Polyps / surgery. Male. Middle Aged. Pancreaticoduodenectomy. Polyps / surgery. Recurrence


54. Di Sandro S, Slim AO, Lauterio A, Giacomoni A, Mangoni I, Aseni P, Pirotta V, Aldumour A, Mihaylov P, De Carlis L: Liver adenomatosis: a rare indication for living donor liver transplantation. Transplant Proc; 2009 May;41(4):1375-7
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  • [Title] Liver adenomatosis: a rare indication for living donor liver transplantation.
  • Liver adenomatosis (LA) is a rare benign disease of the liver with unclear pathogenesis, which is characterized by multiple hepatic adenomas.
  • A 48-year-old woman developed multiple liver adenomas.
  • Thirty-four months later, she developed recurrence of multiple hepatic adenomas and 2 nodules were highly suspect for hepatocellular carcinoma.


55. Scurry J, van der Putte SC, Pyman J, Chetty N, Szabo R: Mammary-like gland adenoma of the vulva: review of 46 cases. Pathology; 2009;41(4):372-8
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  • Unusual architectural patterns resembled breast lesions such as erosive adenomatosis, sclerosing adenosis and ductal adenoma.
  • The ductal cell and a site compatible with and/or the presence of adjacent normal MLG are the most characteristic features.
  • Unusual vulvar tumours, which have been previously reported as erosive adenomatosis, sclerosing adenosis, papillary adenofibroma, syringocystadenoma papilliferans, etc., are variants of MLG adenomas.

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  • (PMID = 19404851.001).
  • [ISSN] 1465-3931
  • [Journal-full-title] Pathology
  • [ISO-abbreviation] Pathology
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 46
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56. Bechmann LP, Hilgard P, Frilling A, Schumacher B, Baba HA, Gerken G, Zoepf T: Successful photodynamic therapy for biliary papillomatosis: a case report. World J Gastroenterol; 2008 Jul 14;14(26):4234-7
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  • After drainage of the left hepatic duct with a percutaneous transhepatic cholangial drainage (PTCD) catheter, a recurrent biliary adenomatosis was diagnosed by cholangioscopy.
  • Three mo after he received further photodynamic therapies, the bile duct epithelium appeared normal and the patient had no signs of adenomatosis, both macroscopically and histologically.

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  • [Cites] Br J Surg. 1996 Dec;83(12):1715-6 [9038549.001]
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  • (PMID = 18636672.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2725388
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57. Oyama T, Yamada Y, Hata K, Tomita H, Hirata A, Sheng H, Hara A, Aoki H, Kunisada T, Yamashita S, Mori H: Further upregulation of beta-catenin/Tcf transcription is involved in the development of macroscopic tumors in the colon of ApcMin/+ mice. Carcinogenesis; 2008 Mar;29(3):666-72
Mouse Genome Informatics (MGI). Mouse Genome Informatics (MGI) .

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  • Apc(Min/+) mouse, a mouse model for human familial adenomatosis polyposis, contains a truncating mutation in the Apc gene and spontaneously develops intestinal tumors.

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  • (PMID = 18204079.001).
  • [ISSN] 1460-2180
  • [Journal-full-title] Carcinogenesis
  • [ISO-abbreviation] Carcinogenesis
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Dkk1 protein, mouse; 0 / Intercellular Signaling Peptides and Proteins; 0 / T Cell Transcription Factor 1; 0 / Wnt Proteins; 0 / beta Catenin
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58. Henopp T, Anlauf M, Schmitt A, Schlenger R, Zalatnai A, Couvelard A, Ruszniewski P, Schaps KP, Jonkers YM, Speel EJ, Pellegata NS, Heitz PU, Komminoth P, Perren A, Klöppel G: Glucagon cell adenomatosis: a newly recognized disease of the endocrine pancreas. J Clin Endocrinol Metab; 2009 Jan;94(1):213-7
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  • [Title] Glucagon cell adenomatosis: a newly recognized disease of the endocrine pancreas.
  • BACKGROUND: Glucagon-producing tumors are either solitary neoplasms of the pancreas, occasionally associated with a glucagonoma syndrome, or multiple neoplasms associated with multiple endocrine neoplasia type 1 (MEN1).
  • METHODS: Pancreatic tissue from four patients showing multiple neuroendocrine microadenomas and in two cases also macrotumors were screened for hormones using immunohistochemical and morphometric methods.
  • CONCLUSIONS: The findings are sufficiently distinctive to suggest a new neoplastic disease of the endocrine pancreas that we recommend calling glucagon cell adenomatosis.

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  • (PMID = 18957496.001).
  • [ISSN] 0021-972X
  • [Journal-full-title] The Journal of clinical endocrinology and metabolism
  • [ISO-abbreviation] J. Clin. Endocrinol. Metab.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / MEN1 protein, human; 0 / Proto-Oncogene Proteins; 147604-94-2 / Cyclin-Dependent Kinase Inhibitor p27; 9007-92-5 / Glucagon; EC 6.3.2.19 / VHL protein, human; EC 6.3.2.19 / Von Hippel-Lindau Tumor Suppressor Protein
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59. de Ferro SM, Suspiro A, Fidalgo P, Lage P, Rodrigues P, Fragoso S, Vitoriano I, Baltazar C, Albuquerque C, Bettencourt A, Leitão CN: Aggressive phenotype of MYH-associated polyposis with jejunal cancer and intra-abdominal desmoid tumor: report of a case. Dis Colon Rectum; 2009 Apr;52(4):742-5
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  • [Title] Aggressive phenotype of MYH-associated polyposis with jejunal cancer and intra-abdominal desmoid tumor: report of a case.
  • MYH-associated polyposis is an inherited autosomal recessive disease, linked to biallelic germline MYH mutations, which predisposes to the development of multiple colorectal adenomas and cancer.
  • We report the case of a young male patient with an aggressive MYH-associated polyposis phenotype.
  • He presented at aged 30 years with more than 100 colonic polyps and 4 colonic adenocarcinomas.
  • At aged 35 years, Spigelman Stage IV duodenal adenomatosis was detected.
  • Based on this report, we believe that screening of the entire small bowel should be recommended in MYH-associated polyposis patients, especially in those with duodenal adenomas.
  • Similar to patients with familial adenomatous polyposis, desmoid tumors also may be part of the clinical spectrum of MYH-associated polyposis and may prove to be a significant clinical problem in patients submitted to prophylactic colectomy.
  • [MeSH-major] Adenomatous Polyposis Coli / genetics. Colorectal Neoplasms / genetics. Fibromatosis, Aggressive / genetics. Jejunal Neoplasms / genetics. Neoplasms, Multiple Primary / genetics. Peritoneal Neoplasms / genetics

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  • (PMID = 19404084.001).
  • [ISSN] 1530-0358
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] EC 3.2.2.- / DNA Glycosylases
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60. Kadzhaia NR, Virsaladze DK, Tkeshelashvili BD, Dzhavashvili LV, Dzhugeli MK: [Endocrine-metabolic peculiarities in women of reproductive age with hyperplastic processes of cervix and mammary glands]. Georgian Med News; 2006 May;(134):60-3
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  • 72 patients with hyperplastic processes in endomyometrium, uterine cervix (hyperplasia, polyposis, myoma) and mammary glands (fibroadenomatosis, adenomatosis) were selected in main group.


61. Cajaiba MM, Sarita-Reyes C, Zambrano E, Reyes-Múgica M: Mesenchymal hamartoma of the liver associated with features of Beckwith-Wiedemann syndrome and high serum alpha-fetoprotein levels. Pediatr Dev Pathol; 2007 May-Jun;10(3):233-8
MedlinePlus Health Information. consumer health - Liver Diseases.

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  • In addition, we analyze the unusual pancreatic lesion (focal endocrine adenomatosis) leading to severe hyperinsulinemic hypoglycemia in a patient with possible BWS.

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  • [CommentIn] Pediatr Dev Pathol. 2008 Jul-Aug;11(4):264-5 [17990933.001]
  • (PMID = 17535089.001).
  • [ISSN] 1093-5266
  • [Journal-full-title] Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
  • [ISO-abbreviation] Pediatr. Dev. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / alpha-Fetoproteins
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62. Hardy OT, Hernandez-Pampaloni M, Saffer JR, Suchi M, Ruchelli E, Zhuang H, Ganguly A, Freifelder R, Adzick NS, Alavi A, Stanley CA: Diagnosis and localization of focal congenital hyperinsulinism by 18F-fluorodopa PET scan. J Pediatr; 2007 Feb;150(2):140-5
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  • Pathology results confirmed that all 11 had focal adenomatosis, and the locations of these lesions matched the areas of increased [18F]-DOPA uptake on the PET scans in all of the cases.

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  • [CommentIn] J Pediatr. 2007 Feb;150(2):122-4 [17236885.001]
  • (PMID = 17236890.001).
  • [ISSN] 1097-6833
  • [Journal-full-title] The Journal of pediatrics
  • [ISO-abbreviation] J. Pediatr.
  • [Language] eng
  • [Grant] United States / NCRR NIH HHS / RR / M01-RR-00240; United States / NIDDK NIH HHS / DK / R01-DK-56268; United States / NIDDK NIH HHS / DK / T32-DK63688
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 2C598205QX / fluorodopa F 18; 63-84-3 / Dihydroxyphenylalanine
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63. Laurent-Puig P, Zucman-Rossi J: Genetics of hepatocellular tumors. Oncogene; 2006 Jun 26;25(27):3778-86
The Lens. Cited by Patents in .

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  • It includes integration of hepatitis B virus (HBV) DNA, R249S TP53 (tumor protein p53) mutation in aflatoxin B1-exposed patients, KRAS mutations related to vinyl chloride exposure, hepatocyte nuclear factor 1alpha (HNF1alpha) mutations associated to hepatocellular adenomas and adenomatosis polyposis coli (APC) germline mutations predisposing to hepatoblastomas.


64. Sugita A, Koganei K, Kimura H, Yamada K, Futatuki R, Kitoh F, Fukushima T: [Reconstruction of proctocolectomy: which is the best surgical procedure?]. Nihon Geka Gakkai Zasshi; 2008 Sep;109(5):269-73

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  • Total proctocolectomy is commonly performed in patients with ulcerative colitis or familial adenomatosis coli.
  • Postoperative cancer surveillance colonoscopy is recommended in patients with stapled IPAA, and patients with IPAA have also at risk for cancer in the anastomotic site, although at very low incidence.

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  • (PMID = 18939461.001).
  • [ISSN] 0301-4894
  • [Journal-full-title] Nihon Geka Gakkai zasshi
  • [ISO-abbreviation] Nihon Geka Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Japan
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65. Buttrick GJ, Beaumont LM, Leitch J, Yau C, Hughes JR, Wakefield JG: Akt regulates centrosome migration and spindle orientation in the early Drosophila melanogaster embryo. J Cell Biol; 2008 Feb 11;180(3):537-48
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  • We show that Akt is enriched at the embryonic cortex and is required for phosphorylation of the glycogen synthase kinase-3beta homologue Zeste-white 3 kinase (Zw3) and for the cortical localizations of the adenomatosis polyposis coli (APC)-related protein APC2/E-APC and the MT + Tip protein EB1.

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  • (PMID = 18268102.001).
  • [ISSN] 1540-8140
  • [Journal-full-title] The Journal of cell biology
  • [ISO-abbreviation] J. Cell Biol.
  • [Language] eng
  • [Grant] United Kingdom / Biotechnology and Biological Sciences Research Council / / BB/ BBS/B/08019
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / APC2 protein, Drosophila; 0 / Armadillo Domain Proteins; 0 / Drosophila Proteins; 0 / Transcription Factors; 0 / Tumor Suppressor Proteins; 0 / armadillo protein, Drosophila; EC 2.7.11.1 / Proto-Oncogene Proteins c-akt; EC 2.7.11.1 / shaggy protein, Drosophila; EC 2.7.11.26 / Glycogen Synthase Kinase 3
  • [Other-IDs] NLM/ PMC2234228
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66. Ruys AT, Alderlieste YA, Gouma DJ, Dekker E, Mathus-Vliegen EM: Jejunal cancer in patients with familial adenomatous polyposis. Clin Gastroenterol Hepatol; 2010 Aug;8(8):731-3
The Weizmann Institute of Science GeneCards and MalaCards databases. gene/protein/disease-specific - MalaCards for jejunal cancer .

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  • [Title] Jejunal cancer in patients with familial adenomatous polyposis.
  • BACKGROUND & AIMS: Familial adenomatous polyposis (FAP) is an inherited disease affecting approximately 1:10,000 newborns, characterized by the formation of numerous adenomas in the digestive tract.
  • RESULTS: Three patients with FAP aged 71, 57, and 59 years developed advanced duodenal adenomatosis and a jejunal carcinoma, which was associated with poor prognosis in 2 patients.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenoma / diagnosis. Adenomatous Polyposis Coli / complications. Jejunal Neoplasms / diagnosis

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  • [Copyright] Copyright 2010 AGA Institute. Published by Elsevier Inc. All rights reserved.
  • [CommentIn] Clin Gastroenterol Hepatol. 2010 Oct;8(10):904 [20621624.001]
  • (PMID = 20399906.001).
  • [ISSN] 1542-7714
  • [Journal-full-title] Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • [ISO-abbreviation] Clin. Gastroenterol. Hepatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
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67. Belingheri M, Ghio L, Sala A, Menni F, Trespidi L, Ferraresso M, Berardinelli L, Rossi G, Edefonti A, Parini R: Combined liver-kidney transplantation in glycogen storage disease Ia: a case beyond the guidelines. Liver Transpl; 2007 May;13(5):762-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Liver transplantation is the only radical treatment, for which the main indications are hepatic adenomatosis, hepatocellular carcinoma, or severe hepatic dysfunction.


68. Upadhyay G, Goessling W, North TE, Xavier R, Zon LI, Yajnik V: Molecular association between beta-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/beta-catenin signaling. Oncogene; 2008 Oct 2;27(44):5845-55
ZFIN. ZFIN .

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  • Biochemical studies demonstrate that DOCK4 interacts with the beta-catenin degradation complex, consisting of the proteins adenomatosis polyposis coli, Axin and glycogen synthase kinase 3beta (GSK3beta).


69. Virsaladze DK, Tkeshelashvili BD, Dzhavashvili LV, Kadzhaia NR, Khutsishvili MP: [Peculiarities of metabolic characteristics in females of reproductive age with hyperplastic processes of cervix and mammary glands]. Georgian Med News; 2006 Jul;(136):58-61
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  • 72 patients with hyperplastic processes of endometrium and endocervix (hyperplasia, polyposis), myoma of uterus, fibroadenoms and adenomatosis of mammary glands were selected in main group.

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  • (PMID = 16905847.001).
  • [ISSN] 1512-0112
  • [Journal-full-title] Georgian medical news
  • [ISO-abbreviation] Georgian Med News
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Georgia (Republic)
  • [Chemical-registry-number] 0 / Cholesterol, HDL; 0 / Triglycerides
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70. Cadigan KM, Liu YI: Wnt signaling: complexity at the surface. J Cell Sci; 2006 Feb 1;119(Pt 3):395-402
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  • Activation of Fz-LRP promotes the stability and nuclear localization of beta-catenin by compromising the ability of a multiprotein complex containing axin, adenomatosis polyposis coli (APC) and glycogen synthase kinase 3 (GSK3) to target it for degradation and block its nuclear import.
  • The Fz-LRP receptor complex probably accomplishes this by generating multiple signals in the cytoplasm.

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  • (PMID = 16443747.001).
  • [ISSN] 0021-9533
  • [Journal-full-title] Journal of cell science
  • [ISO-abbreviation] J. Cell. Sci.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA95869; United States / NIGMS NIH HHS / GM / R01 GM59846
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Low Density Lipoprotein Receptor-Related Protein-1; 0 / Multiprotein Complexes; 0 / Receptors, Neurotransmitter; 0 / Wnt Proteins
  • [Number-of-references] 131
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71. Bülow S, Bülow C, Vasen H, Järvinen H, Björk J, Christensen IJ: Colectomy and ileorectal anastomosis is still an option for selected patients with familial adenomatous polyposis. Dis Colon Rectum; 2008 Sep;51(9):1318-23
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  • [Title] Colectomy and ileorectal anastomosis is still an option for selected patients with familial adenomatous polyposis.
  • PURPOSE: The risk of rectal cancer after colectomy and ileorectal anastomosis may be reduced in the last decades, as patients with severe polyposis now have an ileoanal pouch.
  • This indicates that ileorectal anastomosis may still be justified in selected patients with mild adenomatosis, especially in young females.
  • [MeSH-major] Adenomatous Polyposis Coli / surgery. Colectomy. Ileum / surgery. Rectal Neoplasms / epidemiology. Rectum / surgery

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  • (PMID = 18523824.001).
  • [ISSN] 1530-0358
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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72. Kámory E, Olasz J, Csuka O: Somatic APC inactivation mechanisms in sporadic colorectal cancer cases in Hungary. Pathol Oncol Res; 2008 Mar;14(1):51-6
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  • The role of germline inactivation of the adenomatosis polyposis coli (APC) gene in hereditary colorectal cancer is well known, being the most important cause of familial adenomatosus polyposis (FAP) syndrome.

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  • (PMID = 18369740.001).
  • [ISSN] 1219-4956
  • [Journal-full-title] Pathology oncology research : POR
  • [ISO-abbreviation] Pathol. Oncol. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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73. Flemming P, Lehmann U, Steinemann D, Kreipe H, Wilkens L: [Hepatocellular adenoma. Malignancy potential and differentiation from hepatocellular carcinoma]. Pathologe; 2006 Jul;27(4):238-43
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  • A limitation of particular HCA in genetic and metabolic diseases, children, adult males, adenomatosis, and HCA-like tumors with known risk factors of HCC would seem pragmatically meaningful.

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  • (PMID = 16736176.001).
  • [ISSN] 0172-8113
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] Comparative Study; English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 39
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74. Rosoff PM, Larrier N, Rice HE: Intra-abdominal desmoid tumor after successful treatment for Hodgkin disease. Pediatr Blood Cancer; 2005 Oct 15;45(5):728-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The tumor did not occur at either a surgical site or within a radiation field.
  • She did not carry a mutation for familial adenomatosis polypoli.

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  • (PMID = 16035093.001).
  • [ISSN] 1545-5009
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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75. Akatsu T, Aiura K, Takahashi S, Kameyama K, Kitajima M, Kitagawa Y: Recurrent pancreatitis caused by ampullary carcinoma and minor papilla adenoma in familial polyposis: report of a case. Surg Today; 2008;38(5):440-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Recurrent pancreatitis caused by ampullary carcinoma and minor papilla adenoma in familial polyposis: report of a case.
  • We report a case of relapsing pancreatitis in familial adenomatous polyposis (FAP) with severe duodenal adenomatosis (Spigelman's stage IV).
  • Upper endoscopy showed multiple duodenal adenomas including carcinoma involving the papilla of Vater.
  • [MeSH-major] Adenocarcinoma / etiology. Adenoma / etiology. Adenomatous Polyposis Coli / complications. Ampulla of Vater. Common Bile Duct Neoplasms / etiology. Pancreatic Neoplasms / etiology. Pancreatitis / etiology


76. Dawson S, Else RW, Rhind SM, Collie DD: Diagnostic value of cytology of bronchoalveolar fluid for lung diseases of sheep. Vet Rec; 2005 Oct 8;157(15):433-6
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  • The diffuse lung diseases, maedi and adenomatosis, were both characterised by an increase in overall cellularity and by increases in the percentages of lymphocytes and neutrophils, respectively.

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  • (PMID = 16215243.001).
  • [ISSN] 0042-4900
  • [Journal-full-title] The Veterinary record
  • [ISO-abbreviation] Vet. Rec.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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77. Kim JC, Cho YK, Roh SA, Yu CS, Gong G, Jang SJ, Kim SY, Kim YS: Individual tumorigenesis pathways of sporadic colorectal adenocarcinomas are associated with the biological behavior of tumors. Cancer Sci; 2008 Jul;99(7):1348-54
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  • Individual steps in the tumorigenesis pathway, that is, adenomatosis polyposis coli (APC), Wnt-activated, base excision repair mutations, mismatch repair defects, RAF-mediated, transforming growth factor (TGF)-beta-suppressed, bone morphogenic protein (BMP)-suppressed, and p53 alterations, were examined in terms of genetic and epigenetic changes, as well as protein expression.

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  • [ErratumIn] Cancer Sci. 2008 Jul;99(7):1499
  • (PMID = 18422752.001).
  • [ISSN] 1349-7006
  • [Journal-full-title] Cancer science
  • [ISO-abbreviation] Cancer Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] EC 2.7.11.1 / raf Kinases
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78. Ghosh N, Chaki R, Mandal V, Mandal SC: COX-2 as a target for cancer chemotherapy. Pharmacol Rep; 2010 Mar-Apr;62(2):233-44
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Moreover, clinical trials in patients with familial adenomatosis polyposis syndrome have shown the efficacy of selective COX-2 inhibitors in the reduction of the number and size of colorectal polyps.

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  • (PMID = 20508278.001).
  • [ISSN] 1734-1140
  • [Journal-full-title] Pharmacological reports : PR
  • [ISO-abbreviation] Pharmacol Rep
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; 0 / Cyclooxygenase 2 Inhibitors; 0 / Pyrazoles; 0 / Sulfonamides; EC 1.14.99.1 / Cyclooxygenase 2; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; EC 2.7.11.1 / Protein-Serine-Threonine Kinases; EC 2.7.11.2 / pyruvate dehydrogenase (acetyl-transferring) kinase; EC 3.6.3.8 / Sarcoplasmic Reticulum Calcium-Transporting ATPases; JCX84Q7J1L / Celecoxib
  • [Number-of-references] 72
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79. Zlobec I, Terracciano L, Jass JR, Lugli A: Value of staining intensity in the interpretation of immunohistochemistry for tumor markers in colorectal cancer. Virchows Arch; 2007 Oct;451(4):763-9
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  • A tissue microarray of 1,197 colorectal cancers was immunostained for p53, Her2/neu, epidermal growth factor receptor (EGFR), adenomatosis polyposis coli (APC), and beta-catenin.
  • [MeSH-minor] Adenomatous Polyposis Coli Protein / metabolism. Humans. Multivariate Analysis. Neoplasm Staging. Receptor, Epidermal Growth Factor / metabolism. Receptor, ErbB-2 / metabolism. Tumor Suppressor Protein p53 / metabolism. beta Catenin / metabolism

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  • (PMID = 17674041.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Adenomatous Polyposis Coli Protein; 0 / Biomarkers, Tumor; 0 / Coloring Agents; 0 / Tumor Suppressor Protein p53; 0 / beta Catenin; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; EC 2.7.10.1 / Receptor, ErbB-2
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80. von Meyenfeldt EM, Mantel SF, Gouma DJ, van Gulik TM: [Tumors in the gallbladder: a possible differentiation between malignant and benign tumours]. Ned Tijdschr Geneeskd; 2007 May 12;151(19):1049-54
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  • In a 59-year-old woman with pain in the right upper abdomen, echography and CT-scan revealed adenomatosis of the gallbladder.
  • Her symptoms did not disappear after cholecystectomy, even though echography showed no further abnormality.
  • In a 46-year-old man with fever and weight loss, echography revealed two polyps in the gallbladder.
  • Following cholecystectomy, histopathology revealed cholesterol polyps and an infection with Entamoeba coli.
  • [MeSH-minor] Aged. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging / methods. Male. Middle Aged. Polyps / diagnosis. Polyps / surgery. Tomography, X-Ray Computed / methods. Ultrasonography / methods

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  • [CommentIn] Ned Tijdschr Geneeskd. 2007 Jul 21;151(29):1653; author reply 1653 [17727189.001]
  • [CommentIn] Ned Tijdschr Geneeskd. 2007 Jul 21;151(29):1652-3; author reply 1653 [17729454.001]
  • [CommentOn] Ned Tijdschr Geneeskd. 2007 May 12;151(19):1083-6 [17552418.001]
  • (PMID = 17552411.001).
  • [ISSN] 0028-2162
  • [Journal-full-title] Nederlands tijdschrift voor geneeskunde
  • [ISO-abbreviation] Ned Tijdschr Geneeskd
  • [Language] dut
  • [Publication-type] Case Reports; Comment; English Abstract; Journal Article
  • [Publication-country] Netherlands
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81. Zhang W, Chuang YJ, Jin T, Swanson R, Xiong Y, Leung L, Olson ST: Antiangiogenic antithrombin induces global changes in the gene expression profile of endothelial cells. Cancer Res; 2006 May 15;66(10):5047-55
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  • In contrast, most up-regulated genes (e.g., caspase-3, p21, tissue inhibitor of metalloproteinases 1, 2, and 3, and adenomatosis polyposis coli) are known for their antiangiogenic functions which include the promotion of cell apoptosis and cell cycle arrest and the inhibition of tumor growth and metastasis.

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  • (PMID = 16707426.001).
  • [ISSN] 0008-5472
  • [Journal-full-title] Cancer research
  • [ISO-abbreviation] Cancer Res.
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / HL-39888
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Angiogenesis Inhibitors; 0 / Antithrombins; 103107-01-3 / Fibroblast Growth Factor 2
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82. Kogan EA, Tyong FV, Demura SA: [The mechanism of lung tissue remodeling in the progression of idiopathic pulmonary fibrosis]. Arkh Patol; 2010 Jul-Aug;72(4):30-6
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  • Thus, lung tissue remodeling in the progression of IPF from the early to late stage of the disease comprises interrelated processes that are largely localized in the BATZ, such as immune inflammation with pathological reparation, neoangiogenesis, apoptosis, and proliferation of epitheliocytes and myofibroblasts, which lead to the development of interstitial fibrosis and adenomatosis of the lung.


83. Amemori H, Hyakutake M, Maeda Y, Tomita Y, Mitsumizo S, Oishi H, Koizumi S, Nakashima M, Araki K: Survival case of Vibrio vulnificus infection with multiple endocrine neoplasia type I. Fukuoka Igaku Zasshi; 2007 Sep;98(9):346-52
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  • [Title] Survival case of Vibrio vulnificus infection with multiple endocrine neoplasia type I.
  • A 35-year-old female with malabsorption syndrome who underwent a pancreatoduodenectomy for multiple endocrine adenomatosis 13 years prior was admitted to our hospital with diarrhea, general fatigue, high fever, and eruption in the lower legs.
  • [MeSH-major] Immunocompromised Host. Multiple Endocrine Neoplasia Type 1 / complications. Vibrio Infections / etiology. Vibrio Infections / therapy. Vibrio vulnificus

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  • (PMID = 17974078.001).
  • [ISSN] 0016-254X
  • [Journal-full-title] Fukuoka igaku zasshi = Hukuoka acta medica
  • [ISO-abbreviation] Fukuoka Igaku Zasshi
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; 0 / Catecholamines; 9M416Z9QNR / Ceftazidime; FYY3R43WGO / Minocycline; IY9XDZ35W2 / Glucose
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84. Steinemann D, Skawran B, Becker T, Tauscher M, Weigmann A, Wingen L, Tauscher S, Hinrichsen T, Hertz S, Flemming P, Flik J, Wiese B, Kreipe H, Lichter P, Schlegelberger B, Wilkens L: Assessment of differentiation and progression of hepatic tumors using array-based comparative genomic hybridization. Clin Gastroenterol Hepatol; 2006 Oct;4(10):1283-91
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  • However, in 2 adenomas with a known history of glycogenosis type I and adenomatosis hepatis gains of 1q were found, too.

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  • (PMID = 16979954.001).
  • [ISSN] 1542-3565
  • [Journal-full-title] Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • [ISO-abbreviation] Clin. Gastroenterol. Hepatol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm
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85. Kalimutho M, Blanco Gdel V, Gravina P, Cretella M, Mannucci L, Mannisi E, Formosa A, Pallone F, Federici G, Bernardini S: Quantitative denaturing high performance liquid chromatography (Q-dHPLC) detection of APC long DNA in faeces from patients with colorectal cancer. Clin Chem Lab Med; 2010 Sep;48(9):1303-11
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  • Adenomatosis polyposis coli (APC)-Long-DNA and its mutations were analysed using dHPLC and the Sanger sequencing method.

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  • (PMID = 20504269.001).
  • [ISSN] 1437-4331
  • [Journal-full-title] Clinical chemistry and laboratory medicine
  • [ISO-abbreviation] Clin. Chem. Lab. Med.
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Actins; 9007-49-2 / DNA
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86. Seldin DC, Landesman-Bollag E, Farago M, Currier N, Lou D, Dominguez I: CK2 as a positive regulator of Wnt signalling and tumourigenesis. Mol Cell Biochem; 2005 Jun;274(1-2):63-7
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Multiple signalling and oncogene pathways could be regulated by CK2 in this process.
  • Inactivating mutations in the adenomatosis polyposis coli (APC) gene, which encodes a carrier protein for beta-catenin, or stabilizing mutations in beta-catenin itself, frequently occur in human tumours.

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  • (PMID = 16342409.001).
  • [ISSN] 0300-8177
  • [Journal-full-title] Molecular and cellular biochemistry
  • [ISO-abbreviation] Mol. Cell. Biochem.
  • [Language] eng
  • [Grant] United States / NIEHS NIH HHS / ES / P01 ES11624; United States / NCI NIH HHS / CA / R01 CA71796; United States / NCI NIH HHS / CA / T32 CA064070
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Wnt Proteins; 0 / beta Catenin; EC 2.7.11.1 / Casein Kinase II; EC 2.7.11.26 / Glycogen Synthase Kinase 3
  • [Number-of-references] 16
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87. Kazanjian A, Noah T, Brown D, Burkart J, Shroyer NF: Atonal homolog 1 is required for growth and differentiation effects of notch/gamma-secretase inhibitors on normal and cancerous intestinal epithelial cells. Gastroenterology; 2010 Sep;139(3):918-28, 928.e1-6
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  • METHODS: We studied mice with intestine-specific disruption of Atoh1 (Atoh1(Deltaintestine)), the adenomatosis polyposis coli (APC)(min) mutation, both mutations (Atoh1(Deltaintestine); APC(min)), or littermate controls; mice were given GSI or vehicle.

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  • [Copyright] Copyright © 2010 AGA Institute. Published by Elsevier Inc. All rights reserved.
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  • (PMID = 20621629.001).
  • [ISSN] 1528-0012
  • [Journal-full-title] Gastroenterology
  • [ISO-abbreviation] Gastroenterology
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / K01 DK071686; United States / NIDDK NIH HHS / DK / K01 DK071686; United States / NIDDK NIH HHS / DK / P30 DK078392; United States / NCI NIH HHS / CA / R01 CA142826; United States / NCI NIH HHS / CA / R01 CA142826; United States / NCI NIH HHS / CA / R01 CA142826-01; United States / NIDDK NIH HHS / DK / R03 DK084167; United States / NIDDK NIH HHS / DK / R03 DK084167-01; United States / NIDDK NIH HHS / DK / T35 DK060444
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / ATOH1 protein, human; 0 / Antineoplastic Agents; 0 / Atoh1 protein, mouse; 0 / Basic Helix-Loop-Helix Transcription Factors; 0 / RNA, Messenger; 0 / Receptors, Notch; EC 3.4.- / Amyloid Precursor Protein Secretases
  • [Other-IDs] NLM/ NIHMS215773; NLM/ PMC3197859
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88. Widimský J Jr, Zelinka T, Petrák O, Strauch B, Safarík L, Kasalický M, Vranková A, Holaj R: [Diagnostic and therapeutic procedures in pheochromocytoma: current trends]. Vnitr Lek; 2007 Apr;53(4):428-33
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  • 5 gene mutations have so far been identified that may be responsible for the familial form of pheochromacytoma: mutation of the von Hippel-Lindau (VHL) gene, leading to the onset of VHL syndrome, mutation of the RET-proto-oncogene in multiple endocrine adenomatosis type 2, mutation of the type 1 gene for neurofibromatosis, which is associated with von Recklinghausen's disease and finally mutation of the genes encoding the B and D subunits of succinated hydrogenase (SDHB, SDHD), which are associated with familial paragangliomas and pheochromacytoma.
  • The diagnosis of extraadrenal or multiple forms can use not only CT/MR but also imaging using the radiopharmaceutical 123I-Metaiodobenzylguanidine (MIBG) or 18F-fluorodopamine PET (only available in the USA).
  • [MeSH-minor] Humans. Hypertension / etiology. Multiple Endocrine Neoplasia Type 2a / diagnosis. Neurofibromatosis 1 / diagnosis. Paraganglioma / diagnosis. von Hippel-Lindau Disease / diagnosis. von Hippel-Lindau Disease / etiology

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  • (PMID = 17578179.001).
  • [ISSN] 0042-773X
  • [Journal-full-title] Vnitr̆ní lékar̆ství
  • [ISO-abbreviation] Vnitr Lek
  • [Language] cze
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Czech Republic
  • [Number-of-references] 25
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89. Komaba H, Takeda Y, Shin J, Tanaka R, Kakuta T, Tominaga Y, Fukagawa M: Reversed whole PTH/intact PTH ratio as an indicator of marked parathyroid enlargement: five case studies and a literature review. NDT Plus; 2008 Aug;1(Suppl 3):iii54-iii58
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  • In the case of a single enlarged gland, the pathological pattern and heterogeneous expression of parathyroid adenomatosis 1/cyclin D1 suggested it to be a single nodule of uraemic hyperparathyroidism rather than sporadic primary adenoma.

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  • (PMID = 25983975.001).
  • [ISSN] 1753-0784
  • [Journal-full-title] NDT plus
  • [ISO-abbreviation] NDT Plus
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC4421125
  • [Keywords] NOTNLM ; N-PTH / intact PTH / secondary hyperparathyroidism / single nodule / whole PTH
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90. Astakhova TM, Delone GV, Lyupina YV, Abramova EB, Uryvaeva IV, Sharova NP: Changes in the Proteasome Pool during Malignant Transformation of Mouse Liver Cells. Acta Naturae; 2010 Apr;2(1):102-8

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  • Multiple forms of proteasomes regulate cellular processes by destroying proteins or forming the peptides involved in those processes.
  • Our results indicate that nodular regenerative hyperplasia and adenomatosis may be stages preceding carcinogenesis.

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  • (PMID = 22649635.001).
  • [ISSN] 2075-8251
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  • [ISO-abbreviation] Acta Naturae
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Russia (Federation)
  • [Other-IDs] NLM/ PMC3347545
  • [Keywords] NOTNLM ; 19S proteasome activator / Western blot analysis / adenoma / chymotrypsin–like activity of proteasomes / hepatocellular carcinoma / immunoproteasomes / mouse liver / nodular regenerative hyperplasia of the liver
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91. Entz-Werlé N, Choquet P, Neuville A, Kuchler-Bopp S, Clauss F, Danse JM, Simo-Noumbissie P, Guérin E, Gaub MP, Freund JN, Boehm N, Constantinesco A, Lutz P, Guenot D, Perrin-Schmitt F: Targeted apc;twist double-mutant mice: a new model of spontaneous osteosarcoma that mimics the human disease. Transl Oncol; 2010;3(6):344-53
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  • TWIST and adenomatosis polyposis coli (APC) are critical signaling factors in normal bone development.

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  • (PMID = 21151473.001).
  • [ISSN] 1936-5233
  • [Journal-full-title] Translational oncology
  • [ISO-abbreviation] Transl Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3000459
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92. Radford IR, Lobachevsky PN: Clustered DNA lesion sites as a source of mutations during human colorectal tumourigenesis. Mutat Res; 2008 Nov 10;646(1-2):60-8
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  • We used statistical analyses to search for sets of dinucleotide sequences (designated target sequences) that are present at and in close proximity to mutation sites in four genes associated with human colorectal tumourigenesis (adenomatosis polyposis coli (APC), v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS), phosphoinositide-3-kinase, catalytic, alpha polypeptide (PIK3CA), and tumour protein p53 (TP53)).
  • Our results strongly suggest a statistical association between the presence of multiple, clustered target sequences and mutational events.

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  • (PMID = 18824008.001).
  • [ISSN] 0027-5107
  • [Journal-full-title] Mutation research
  • [ISO-abbreviation] Mutat. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Tumor Suppressor Protein p53; 9007-49-2 / DNA; EC 2.7.1.- / Phosphatidylinositol 3-Kinases; EC 2.7.1.137 / PIK3CA protein, human
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93. Raphe R, Felício HC, Rocha MF, Duca WJ, Arroyo PC Jr, D'Santi Neto D, da Silva RC, da Silva RF: Histopathologic characteristics of incidental hepatocellular carcinoma after liver transplantation. Transplant Proc; 2010 Mar;42(2):505-6
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  • One patient presented with adenomatosis and focus of HCC.

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  • [Copyright] Copyright (c) 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20304178.001).
  • [ISSN] 1873-2623
  • [Journal-full-title] Transplantation proceedings
  • [ISO-abbreviation] Transplant. Proc.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / alpha-Fetoproteins
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94. Miller MJ, Reuter BK, Wallace JL, Sharkey KA: A unique therapeutic approach to emesis and itch with a proanthocyanidin-rich genonutrient. J Transl Med; 2008;6:3
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  • In the ApcMinmouse model of precancerous adenomatosis polyposis, mice received Zangrado (100 mug/ml in drinking water) from the age of 6 - 16 weeks for effects on polyp number.

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  • (PMID = 18205911.001).
  • [ISSN] 1479-5876
  • [Journal-full-title] Journal of translational medicine
  • [ISO-abbreviation] J Transl Med
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / AM 251; 0 / Antiemetics; 0 / Antipruritics; 0 / Morphine Derivatives; 0 / Piperidines; 0 / Plant Extracts; 0 / Proanthocyanidins; 0 / Pyrazoles; 0 / Receptor, Cannabinoid, CB1; 18206-61-6 / proanthocyanidin; 20290-10-2 / morphine-6-glucuronide
  • [Other-IDs] NLM/ PMC2254379
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95. Shimomura Y, Agalliu D, Vonica A, Luria V, Wajid M, Baumer A, Belli S, Petukhova L, Schinzel A, Brivanlou AH, Barres BA, Christiano AM: APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex. Nature; 2010 Apr 15;464(7291):1043-7
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  • Using genetic linkage analysis, we mapped a new locus for the disease to chromosome 18p11.22, and identified a mutation (Leu9Arg) in the adenomatosis polyposis down-regulated 1 (APCDD1) gene in three families.


96. Matsumoto T, Esaki M, Yanaru-Fujisawa R, Moriyama T, Yada S, Nakamura S, Yao T, Iida M: Small-intestinal involvement in familial adenomatous polyposis: evaluation by double-balloon endoscopy and intraoperative enteroscopy. Gastrointest Endosc; 2008 Nov;68(5):911-9
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  • [Title] Small-intestinal involvement in familial adenomatous polyposis: evaluation by double-balloon endoscopy and intraoperative enteroscopy.
  • BACKGROUND: Small-intestinal adenoma occurs in patients with familial adenomatous polyposis (FAP).
  • Phenotypes of FAP and genotypes of adenomatous polyposis coli (APC) were then compared between patients with small-intestinal adenomas and those without.
  • The adenomas occurred predominantly in the jejunum, with a configuration of diminutive polyps in 22 patients.
  • Patients with small-intestinal adenoma had more severe duodenal adenomatosis than those patients without small-intestinal adenoma (P < .001).
  • [MeSH-major] Adenomatous Polyposis Coli / pathology. Duodenal Neoplasms / pathology. Endoscopy, Gastrointestinal. Jejunal Neoplasms / pathology


97. Bioulac-Sage P, Laumonier H, Laurent C, Zucman-Rossi J, Balabaud C: Hepatocellular adenoma: what is new in 2008. Hepatol Int; 2008 Sep;2(3):316-21
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  • Adenomatosis is frequently detected in this context.

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  • (PMID = 19669260.001).
  • [ISSN] 1936-0533
  • [Journal-full-title] Hepatology international
  • [ISO-abbreviation] Hepatol Int
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2716879
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98. Stephen JK, Chen KM, Raitanen M, Grénman S, Worsham MJ: DNA hypermethylation profiles in squamous cell carcinoma of the vulva. Int J Gynecol Pathol; 2009 Jan;28(1):63-75
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  • Of the 22 tumor suppressor genes examined, aberrant methylation was observed for 9 genes: tumor protein p73 (TP73), fragile histidine triad (FHIT), von Hippel-Lindau (VHL), adenomatosis polyposis coli (APC), estrogen receptor 1 (ESR1), cyclin-dependent kinase inhibitor 2B (CDKN2B), death-associated protein kinase 1 (DAPK1), glutathione S-transferase pi (GSTP1), and immunoglobin superfamily, member 4 (IGSF4).
  • Frequent genetic alterations of loss and gain of gene copy number included gain of GSTP1 and multiple endocrine neoplasia type 1 (MEN1), and loss of malignant fibrous histiocytoma amplified sequence 1 (MFHAS1) and IGSF4 in over 50% of the squamous cell carcinoma of the vulva cell lines.

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  • (PMID = 19047905.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] ENG
  • [Grant] United States / NIDCR NIH HHS / DE / R01 DE015990; United States / NIDCR NIH HHS / DE / R01 DE015990-05; United States / NIDCR NIH HHS / DE / DE 15990
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS52427; NLM/ PMC2605778
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99. Poomthavorn P, Wong SH, Higgins S, Werther GA, Russo VC: Activation of a prometastatic gene expression program in hypoxic neuroblastoma cells. Endocr Relat Cancer; 2009 Sep;16(3):991-1004
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  • In hypoxic SH-SY5Y NB cells, real-time PCR analysis showed that the genes involved in maintenance of cell-cell and cell-matrix interactions (i.e. adenomatosis polyposis coli, E-cadherin, catenin, EphB2, fibronectin-1, HTATIP2, tissue inhibitor of metalloprotease-4) were down-regulated by up to 90%, while genes involved in enhancement of metastatic behavior (integrin a7b1, hepatocyte growth factor receptor, transforming growth factor-beta1, VEGF, kisspeptin, interleukin-1beta) were dramatically up-regulated above 200%.

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  • (PMID = 19423615.001).
  • [ISSN] 1479-6821
  • [Journal-full-title] Endocrine-related cancer
  • [ISO-abbreviation] Endocr. Relat. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antimutagenic Agents; 0 / HIF1A protein, human; 0 / Hypoxia-Inducible Factor 1, alpha Subunit; 0 / ID1 protein, human; 0 / ID2 protein, human; 0 / Inhibitor of Differentiation Protein 1; 0 / Inhibitor of Differentiation Protein 2; 0 / VEGFA protein, human; 0 / Vascular Endothelial Growth Factor A; 3G0H8C9362 / Cobalt; EVS87XF13W / cobaltous chloride
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100. Méric JB, Rottey S, Olaussen K, Soria JC, Khayat D, Rixe O, Spano JP: Cyclooxygenase-2 as a target for anticancer drug development. Crit Rev Oncol Hematol; 2006 Jul;59(1):51-64
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  • Moreover, clinical trials in patients with familial adenomatosis polyposis syndrome have shown too the efficacy of non-selective COX inhibitors and recently also of selective COX-2 inhibitors in the reduction of the number and the size of colorectal polyps.

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  • (PMID = 16531064.001).
  • [ISSN] 1040-8428
  • [Journal-full-title] Critical reviews in oncology/hematology
  • [ISO-abbreviation] Crit. Rev. Oncol. Hematol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Cyclooxygenase Inhibitors; EC 1.14.99.1 / Cyclooxygenase 2
  • [Number-of-references] 130
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