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1. Pacheco AJ, Torres JL, de la Guardia FV, Arrabal Polo MA, Gómez AZ: Intraparenchymatous adenomatoid tumor dependent on the rete testis: A case report and review of literature. Indian J Urol; 2009 Jan;25(1):126-8
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  • [Title] Intraparenchymatous adenomatoid tumor dependent on the rete testis: A case report and review of literature.
  • The adenomatoid tumor is the most frequent paratesticular tumor.
  • It is a benign tumor, which in women is mainly found in the uterus and the fallopian tubes, while in men it is most frequently found in the epididymis.
  • The clinical signs and imaging studies are, on many occasions, difficult to differentiate from malign intratesticular solid tumor, which can result in unnecessary orchidectomies.
  • We present a new case of intraparenchymatous adenomatoid tumor dependent on the rete testis.

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  • [Cites] Eur Urol. 1996;30(1):127-8 [8854081.001]
  • [Cites] J Urol. 2004 May;171(5):1765-72 [15076274.001]
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  • (PMID = 19468443.001).
  • [ISSN] 0970-1591
  • [Journal-full-title] Indian journal of urology : IJU : journal of the Urological Society of India
  • [ISO-abbreviation] Indian J Urol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2684313
  • [Keywords] NOTNLM ; Adenomatoid tumor / diagnosis and ultrasound
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2. Crippa S, Di Bella C, Faravelli A: Skin adnexal neoplasm closely resembling adenomatoid tumor: a unique occurrence. Int J Surg Pathol; 2006 Apr;14(2):177-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Skin adnexal neoplasm closely resembling adenomatoid tumor: a unique occurrence.
  • We describe a primary skin neoplasm located in the left chest wall that closely resembled adenomatoid tumor of male and female genital tract.
  • The tumor involved the dermis and subcutaneous tissue and measured 0.7 cm in greatest diameter.
  • We are unaware of a previous description of this morphologic pattern in a primary skin tumor, which we have interpreted as of skin adnexal and specifically of eccrine sweat gland origin.
  • [MeSH-minor] Adenomatoid Tumor / pathology. Aged. Breast Neoplasms / surgery. Carcinoma, Ductal / surgery. Diagnosis, Differential. Female. Humans. Immunohistochemistry

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  • (PMID = 16703184.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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3. Hong R, Choi DY, Choi SJ, Lim SC: Multicentric infarcted leiomyoadenomatoid tumor: a case report. Int J Clin Exp Pathol; 2009;2(1):99-103
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multicentric infarcted leiomyoadenomatoid tumor: a case report.
  • Adenomatoid tumor is a benign, usually small lesion that may be found within the wall of fallopian tubes or beneath the uterine serosa near the uterine cornu.
  • It is often accompanied by smooth muscle hypertrophy that may obscure the adenomatoid tumor.
  • We herein report a very unusual case of infarcted leiomyoadenomatoid tumor of the uterus and ovary in a 24-year-old woman who presented with severe lower abdominal pain and masses in the uterus and right ovary.
  • Laparoscopy-assisted transvaginal mass removal was performed under the clinical impression of a uterine leiomyoma and benign ovarian teratoma.
  • On a microscopic examination, prominent fascicles of smooth muscle separated or infiltrated by cuboidal or signet ring-like vacuolated cells, as well as tubular formations lined by flattened mesothelial cells and extensive necrosis were observed in both masses.
  • The microscopic appearance often suggested the possibility of a malignant neoplasm due to irregular pseudoinfiltration with atypical cuboidal cells and the paucity of a typical adenomatoid tumor due to infarction, and the presence of epithelial-appearing cells in the hypertrophic smooth muscle bundles that mimicked an infiltrating carcinoma for a leiomyoma or myometrium.
  • These unemphasized features of leiomyoadenomatoid tumors may potentially lead to more aggressive therapy than warranted if not correctly interpreted, especially for infarcted cases.

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  • [Cites] Int J Gynecol Pathol. 2007 Jan;26(1):16-20 [17197891.001]
  • [Cites] Arch Gynecol Obstet. 2001 Aug;265(3):151-4 [11561745.001]
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  • (PMID = 18830386.001).
  • [ISSN] 1936-2625
  • [Journal-full-title] International journal of clinical and experimental pathology
  • [ISO-abbreviation] Int J Clin Exp Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Leiomyoadenomatoid tumor / infarction / ovary / uterus
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4. Ordóñez NG: D2-40 and podoplanin are highly specific and sensitive immunohistochemical markers of epithelioid malignant mesothelioma. Hum Pathol; 2005 Apr;36(4):372-80
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  • [Title] D2-40 and podoplanin are highly specific and sensitive immunohistochemical markers of epithelioid malignant mesothelioma.
  • The observation that both of these markers are also expressed in normal and reactive mesothelial cells prompted an investigation into their potential value in the diagnosis of mesotheliomas.
  • To determine whether podoplanin and D2-40 had any use in the diagnosis of these tumors, 40 mesotheliomas (29 epithelioid, 5 biphasic, and 6 sarcomatoid), 34 carcinomas of the lung (24 adenocarcinomas, 10 squamous carcinomas), 80 nonpulmonary adenocarcinomas (17 ovary, 10 breast, 10 colon, 10 kidney, 5 endometrium, 5 stomach, 5 pancreas, 5 prostate, 3 thyroid), 12 synovial sarcomas (6 biphasic and 6 monophasic), 5 angiosarcomas, and 2 adenomatoid tumors were immunostained with a monoclonal antibody to podoplanin and with the D2-40 antibody.
  • Reactivity for both D2-40 and podoplanin was obtained in 25 (86%) of the 29 epithelioid mesotheliomas but in none of the carcinomas or sarcomatoid mesotheliomas.
  • Positivity for D2-40 and podoplanin was also seen in the epithelioid components of 4 of 5 biphasic mesotheliomas and 4 of 6 synovial sarcomas, whereas the spindle cell components of these tumors were negative as were the monophasic synovial sarcomas.
  • Both of the adenomatoid tumors were also positive for D2-40 and podoplanin, a finding which provides further support for the mesothelial derivation of these tumors.
  • It is concluded that, because of their high specificity and sensitivity for epithelioid mesotheliomas, D2-40 and podoplanin are very useful markers for the diagnosis of these tumors.
  • [MeSH-major] Antibodies, Monoclonal / analysis. Membrane Glycoproteins / analysis. Mesothelioma / diagnosis
  • [MeSH-minor] Antibodies, Monoclonal, Murine-Derived. Antigens, Neoplasm / immunology. Biomarkers, Tumor. Female. Humans. Immunohistochemistry. Male. Sensitivity and Specificity

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  • (PMID = 15891998.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Membrane Glycoproteins; 0 / PDPN protein, human; 0 / monoclonal antibody D2-40; 0 / oncofetal antigens
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5. Argeitis J, Botsis D, Kairi-Vassilatou E, Hasiakos D, Papakonstantinou K, Kondi-Pafiti A: Congenital cystic adenomatoid lung malformation: report of two cases and literature review. Clin Exp Obstet Gynecol; 2008;35(1):76-80
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  • [Title] Congenital cystic adenomatoid lung malformation: report of two cases and literature review.
  • Congenital cystic adenomatoid malformations of the fetal lung (CCAM) are rare embryonic developmental abnormalities.
  • They are considered as benign hamartomatous or dysplastic lung tumors characterized by overgrowth of the terminal respiratory bronchioles at the expense of the saccular spaces.
  • Two cases of congenital cystic adenomatoid malformation of the fetal lung diagnosed in our institution during the last four years are reported.
  • [MeSH-major] Cystic Adenomatoid Malformation of Lung, Congenital / pathology. Cystic Adenomatoid Malformation of Lung, Congenital / ultrasonography. Ultrasonography, Prenatal

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  • (PMID = 18390089.001).
  • [ISSN] 0390-6663
  • [Journal-full-title] Clinical and experimental obstetrics & gynecology
  • [ISO-abbreviation] Clin Exp Obstet Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 11
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6. Hartel PH, Fanburg-Smith JC, Frazier AA, Galvin JR, Lichy JH, Shilo K, Franks TJ: Primary pulmonary and mediastinal synovial sarcoma: a clinicopathologic study of 60 cases and comparison with five prior series. Mod Pathol; 2007 Jul;20(7):760-9
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  • Radiologically, tumors were well delineated with distinctive magnetic resonance imaging features and little vascular enhancement.
  • In all, 21/46 patients died of disease within 5 years.
  • Histologically, all tumors had dense cellularity, interlacing fascicles, hyalinized stroma, and mast cell influx.
  • Unusual histological features included Verocay body-like formations (7/60), vague rosettes (6/60), well-formed papillary structures (3/60), adenomatoid change (3/60), and rhabdoid morphology (2/60).
  • Immunohistochemistry demonstrated expression of pancytokeratin (39/58), epithelial membrane antigen (29/53), cytokeratin 7 (26/40), cytokeratin 5/6 (5/7), calretinin (15/23), CD99 (19/23), bcl-2 (24/24), CD56 (11/11), S-100 (9/51), and smooth muscle actin (8/32).
  • Compared with soft tissue synovial sarcoma, primary pulmonary and mediastinal synovial sarcoma has less calcification, less obvious mast cell influx, and less radiologic vascularity, but similar magnetic resonance imaging features, percentage of poorly differentiated tumors, and number of t(x;18)-positive tumors.
  • Awareness of focal unusual histology can prevent misdiagnosis particularly in t(x;18)-negative tumors.

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  • (PMID = 17464314.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD56; 0 / CALB2 protein, human; 0 / CD99 protein, human; 0 / Calbindin 2; 0 / Cell Adhesion Molecules; 0 / Oncogene Proteins, Fusion; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / S100 Calcium Binding Protein G; 0 / S100 Proteins; 0 / SYT-SSX fusion protein; 68238-35-7 / Keratins
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7. Minato H, Nojima T, Kurose N, Kinoshita E: Adenomatoid tumor of the pleura. Pathol Int; 2009 Aug;59(8):567-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid tumor of the pleura.
  • A case of adenomatoid tumor of the pleura is reported, and its differential diagnosis from benign and malignant pleural lesions is discussed.
  • A 7 mm, circumscribed tumor had characteristic features of adenomatoid tumor.
  • The tumor was composed of an aggregation of irregularly shaped tubulocystic spaces with fibrous stoma.
  • On immunohistochemistry the tumor cells were positive for AE1/AE3, CAM5.2, vimentin, cytokeratin 5/6, D2-40, calretinin, thrombomodulin, and WT-1, but negative for CEA, Leu M1 (CD15), thyroid transcription factor-1, epithelial membrane antigen, desmin, glucose transporter-1 (GLUT-1), CD31, and CD34.
  • Adenomatoid tumor of the pleura is rare, and the pathogenesis has not been elucidated.
  • Recognition of these benign mesothelial lesions in the pleura is important to avoid misdiagnosis.
  • The immunohistochemistry in the present case supports its mesothelial origin.
  • [MeSH-major] Adenomatoid Tumor / pathology. Neoplasms, Multiple Primary / pathology. Pleural Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Dermatomyositis / complications. Esophageal Neoplasms / complications. Esophageal Neoplasms / pathology. Female. Humans. Immunohistochemistry. Incidental Findings. Liver Cirrhosis, Biliary / complications. Middle Aged

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  • (PMID = 19627540.001).
  • [ISSN] 1440-1827
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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8. Sieunarine K, Cowie AS, Bartlett JD, Lindsay I, Smith JR: A novel approach in the management of a recurrent adenomatoid tumor of the uterus utilizing a Strassman technique. Int J Gynecol Cancer; 2005 Jul-Aug;15(4):671-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A novel approach in the management of a recurrent adenomatoid tumor of the uterus utilizing a Strassman technique.
  • Adenomatoid tumors of the uterus are uncommon benign lesions derived from mesothelium, with a prevalence of 1.2% in one study of 1 000 unselected hysterectomy specimens.
  • They are usually small and near the serosal surface; however, they may be large and diffuse (giant adenomatoid tumors).
  • This transpired to be an adenomatoid tumor, and she underwent three transcervical resections of the tumor (TCRT) over a period of 12 months for tumor recurrence and failure of symptom resolution.
  • A specialist opinion on the suitability of vascular embolization of the tumor judged that it would be ineffective for this lesion.
  • She then underwent a Strassman procedure and removal of the adenomatoid tumor.
  • This involved dissection of ureters and pelvic vasculature, selective temporary ligation of uterine arteries, hemisection of the uterus, and excision of the tumor with frozen sections to ensure clear tumor margins and resuturing of the uterine halves.
  • Temporary vascular occlusion of the uterine arteries and ovarian vessels allowed a Strassman procedure, which resulted in successful resection of a recurrent giant adenomatoid tumor of the uterus, with fertility preservation in a young nulliparous woman.
  • Two and a half years on there is no evidence of tumor recurrence.
  • [MeSH-major] Adenomatoid Tumor / surgery. Gynecologic Surgical Procedures / methods. Neoplasm Recurrence, Local / surgery. Uterine Neoplasms / surgery. Uterus / blood supply

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  • (PMID = 16014122.001).
  • [ISSN] 1048-891X
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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9. Martínez A, Mosqueda-Taylor A, Marchesani FJ, Brethauer U, Spencer ML: Adenomatoid odontogenic tumor concomitant with cystic complex odontoma: case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2009 Oct;108(4):e25-9
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  • [Title] Adenomatoid odontogenic tumor concomitant with cystic complex odontoma: case report.
  • This case report describes a 10-year-old female patient with an adenomatoid odontogenic tumor developing together with a cystic complex odontoma.
  • [MeSH-major] Mandibular Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Odontogenic Tumors / pathology. Odontoma / pathology

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  • (PMID = 19778732.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Keratin-1; 0 / Keratin-14; 0 / Keratin-19; 0 / Keratin-3; 0 / Keratin-5; 0 / Keratin-8; 0 / Ki-67 Antigen; 147785-83-9 / Keratin-10
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10. Asghar S, Qureshi N, Awan A: Benign mesothelioma of peritoneum presenting as a pelvic mass. J Coll Physicians Surg Pak; 2008 Nov;18(11):723-5
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  • [Title] Benign mesothelioma of peritoneum presenting as a pelvic mass.
  • A large solitary multiloculated pelvic cyst in a 40-year-old woman with chronic pelvic pain was diagnosed to be a Multicystic Benign Mesothelioma (MBM) of peritoneum at laparotomy.
  • [MeSH-major] Mesothelioma, Cystic / diagnosis. Ovarian Neoplasms / diagnosis. Pelvic Neoplasms / diagnosis. Pelvic Pain / diagnosis. Peritoneal Neoplasms / diagnosis

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  • (PMID = 18983801.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
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11. Barry P, Chan KG, Hsu J, Quek ML: Adenomatoid tumor of the tunica albuginea. Int J Urol; 2005 May;12(5):516-8
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  • [Title] Adenomatoid tumor of the tunica albuginea.
  • Adenomatoid tumors are benign mesothelial tumors most commonly found in the paratesticular structures, especially the epididymis.
  • Herein, we report a case of adenomatoid tumor originating in the tunica albuginea and mimicking an intratesticular neoplasm.
  • We review the ultrasonographic presentation and literature regarding adenomatoid tumors originating in the tunica albuginea and testicular parenchyma.
  • [MeSH-major] Adenomatoid Tumor / pathology. Testicular Neoplasms / pathology

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  • (PMID = 15948758.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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12. Vera Sempere FJ, Artes Martínez MJ, Vera Sirera B, Bonet Marco J: Follicular adenomatoid odontogenic tumor: immunohistochemical study. Med Oral Patol Oral Cir Bucal; 2006 Jul;11(4):E305-8
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  • [Title] Follicular adenomatoid odontogenic tumor: immunohistochemical study.
  • Adenomatoid odontogenic tumor (AOT) is an uncommon benign odontogenic lesion that affects young patients, with female predominance, mainly in second decade, showing a radiolucent unilocular image associated with an unerupted tooth, usually a canine.
  • In spite of previous and confusing denominations, such as adenoameloblastoma or adenomatoid ameloblastic tumor, AOT is a benign tumor with a very low rate of recurrence, that show a peculiar morphological picture (basaloid appearance with glandular-like structures, calcifying areas, and amiloid-like material) that allow its histopathological recognition.
  • We present a clinicopathological analysis of a case of follicular AOT affecting the mandible in a 9 years-old female patient associated with unerupted lower left canine.
  • According to its benign character and low potential for recurrence, AOT revealed a scant proliferative activity (2-3% nuclei showed Ki-67 positivity) limited to some epithelial nodules (AE1-3 +) of fusiform appearance.
  • [MeSH-major] Mandibular Neoplasms / pathology. Odontogenic Tumors / pathology

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  • (PMID = 16816813.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng; spa
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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13. Nonaka CF, de Souza LB, Quinderé LB: Adenomatoid odontogenic tumour associated with dentigerous cyst--unusual case report. Braz J Otorhinolaryngol; 2007 Jan-Feb;73(1):129-31
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  • [Title] Adenomatoid odontogenic tumour associated with dentigerous cyst--unusual case report.
  • The adenomatoid odontogenic tumor is a relatively uncommon lesion which mainly affects females in their second decade of life, exhibiting predilection for the anterior region of the maxilla.
  • In this paper we present a case of adenomatoid odontogenic tumor associated with a dentigerous cyst affecting the left maxillary region in a 13-year-old female.
  • [MeSH-major] Dentigerous Cyst / pathology. Maxillary Neoplasms / pathology. Odontogenic Tumors / pathology

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  • (PMID = 17505612.001).
  • [ISSN] 1808-8694
  • [Journal-full-title] Brazilian journal of otorhinolaryngology
  • [ISO-abbreviation] Braz J Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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14. Phillips V, McCluggage WG, Young RH: Oxyphilic adenomatoid tumor of the ovary: a case report with discussion of the differential diagnosis of ovarian tumors with vacuoles and related spaces. Int J Gynecol Pathol; 2007 Jan;26(1):16-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Oxyphilic adenomatoid tumor of the ovary: a case report with discussion of the differential diagnosis of ovarian tumors with vacuoles and related spaces.
  • We describe an unusual example of ovarian adenomatoid tumor that was an incidental finding in the ovary of a 52-year-old woman and was characterized by cells with abundant eosinophilic cytoplasm, an occasional feature of the adenomatoid tumor but one that, in an ovarian example, may cause added diagnostic confusion to that already engendered by the rarity of this neoplasm in the ovary.
  • The typical numerous small vacuoles of the neoplasm sometimes had the appearance of signet ring cells.
  • Tumor cells were positive with broad-spectrum cytokeratins as well as mesothelial markers CK5/6, WT1, and calretinin.
  • [MeSH-major] Adenomatoid Tumor / diagnosis. Ovarian Neoplasms / diagnosis

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  • (PMID = 17197891.001).
  • [ISSN] 0277-1691
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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15. Moreira PR, Guimarães MM, Gomes CC, Diniz MG, Brito JA, de Castro WH, Gomez RS: Methylation frequencies of cell-cycle associated genes in epithelial odontogenic tumours. Arch Oral Biol; 2009 Oct;54(10):893-7
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  • [Title] Methylation frequencies of cell-cycle associated genes in epithelial odontogenic tumours.
  • OBJECTIVE: The benign epithelial odontogenic tumours constitute a group of lesions derived from epithelial elements of the tooth-forming apparatus.
  • This group includes lesions of different biological behaviour, such as ameloblastoma, calcifying cystic odontogenic tumour (CCOT) and adenomatoid odontogenic tumour (AOT).
  • The aim of this study was to investigate the methylation status of P16, P21, P27, P53 and RB1 genes in epithelial odontogenic tumours.
  • A high percentage of the odontogenic tumours analysed showed methylation of the P21 gene, in contrast to dental follicles.
  • CONCLUSIONS: Epithelial odontogenic tumours show a distinct methylation profile in cell-cycle associated genes.
  • In addition to this, the current findings show that epigenetic alterations are common events in epithelial odontogenic tumours.
  • [MeSH-major] Cell Cycle Proteins / genetics. DNA Methylation / genetics. DNA, Neoplasm / metabolism. Neoplasm Proteins / genetics. Odontogenic Tumors / genetics
  • [MeSH-minor] Adenoma / genetics. Adenoma / metabolism. Ameloblastoma / genetics. Ameloblastoma / metabolism. Dental Sac / metabolism. Epithelial Cells / metabolism. Humans. Odontogenic Cyst, Calcifying / genetics. Odontogenic Cyst, Calcifying / metabolism. Polymerase Chain Reaction / methods

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  • (PMID = 19679296.001).
  • [ISSN] 1879-1506
  • [Journal-full-title] Archives of oral biology
  • [ISO-abbreviation] Arch. Oral Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Cell Cycle Proteins; 0 / DNA, Neoplasm; 0 / Neoplasm Proteins
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16. Fitzhugh VA, Mirani N: Respiratory epithelial adenomatoid hamartoma: a review. Head Neck Pathol; 2008 Sep;2(3):203-8
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  • [Title] Respiratory epithelial adenomatoid hamartoma: a review.
  • Respiratory epithelial adenomatoid hamartoma (REAH) is an uncommon lesion of the upper aerodigestive tract first described by Wenig and Heffner in 1995 as prominent glandular proliferations lined by ciliated respiratory epithelium originating from the surface epithelium.
  • While REAH is benign, awareness and recognition of the lesion is important because it can be easily confused grossly and microscopically with more threatening tumors such as inverted papilloma and sinonasal carcinoma.
  • [MeSH-minor] Biomarkers / metabolism. Epithelial Cells / metabolism. Epithelial Cells / pathology. Female. Humans. Loss of Heterozygosity. Male

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  • [Cites] J Laryngol Otol. 2002 Apr;116(4):317-8 [11945202.001]
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  • (PMID = 20614315.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers
  • [Other-IDs] NLM/ PMC2807563
  • [Keywords] NOTNLM ; Inverted papilloma / Nasopharynx / Respiratory epithelial adenomatoid hamartoma / Sinonasal adenocarcinoma / Upper aerodigestive tract
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17. Phillips MD, Closmann JJ, Baus MR, Torske KR, Williams SB: Hybrid odontogenic tumor with features of ameloblastic fibro-odontoma, calcifying odontogenic cyst, and adenomatoid odontogenic tumor: a case report and review of the literature. J Oral Maxillofac Surg; 2010 Feb;68(2):470-4
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  • [Title] Hybrid odontogenic tumor with features of ameloblastic fibro-odontoma, calcifying odontogenic cyst, and adenomatoid odontogenic tumor: a case report and review of the literature.
  • [MeSH-major] Mandibular Neoplasms / pathology. Odontogenic Tumors / pathology

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  • (PMID = 20116726.001).
  • [ISSN] 1531-5053
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 15
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18. Shen J, Pinkus GS, Deshpande V, Cibas ES: Usefulness of EMA, GLUT-1, and XIAP for the cytologic diagnosis of malignant mesothelioma in body cavity fluids. Am J Clin Pathol; 2009 Apr;131(4):516-23
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  • [Title] Usefulness of EMA, GLUT-1, and XIAP for the cytologic diagnosis of malignant mesothelioma in body cavity fluids.
  • We compared the effectiveness of epithelial membrane antigen (EMA) with 2 newly described markers, X-linked inhibitor of apoptosis protein (XIAP) and an isoform of glucose transporter (GLUT-1), in the distinction between malignant mesothelioma (MM) and benign effusion (BE) in body cavity fluids.
  • [MeSH-major] Glucose Transporter Type 1 / biosynthesis. Mesothelioma / diagnosis. Mucin-1 / biosynthesis. Pleural Effusion, Malignant / diagnosis. Pleural Neoplasms / diagnosis. X-Linked Inhibitor of Apoptosis Protein / biosynthesis
  • [MeSH-minor] Aged. Aged, 80 and over. Area Under Curve. Biomarkers, Tumor / analysis. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Male. Middle Aged. Sensitivity and Specificity

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  • (PMID = 19289587.001).
  • [ISSN] 1943-7722
  • [Journal-full-title] American journal of clinical pathology
  • [ISO-abbreviation] Am. J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Glucose Transporter Type 1; 0 / Mucin-1; 0 / X-Linked Inhibitor of Apoptosis Protein; 0 / XIAP protein, human
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19. Kayser K, Kosjerina Z, Goldmann T, Kayser G, Kazmierczak B, Vollmer E: Lung carcinoma-associated atypical adenomatoid hyperplasia, squamous cell dysplasia, and chromosome alterations in non-neoplastic bronchial mucosa. Lung Cancer; 2005 Feb;47(2):205-14
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  • [Title] Lung carcinoma-associated atypical adenomatoid hyperplasia, squamous cell dysplasia, and chromosome alterations in non-neoplastic bronchial mucosa.
  • The frequency of phenotype preneoplastic lesions (atypical adenomatoid hyperplasia (AAH) and squamous cell dysplasia (SCD)) was analyzed at distinct distances from the tumor boundary in 150 lung carcinomas.
  • The degree of cellular atypia decreased with increasing distance from tumor boundary in both AAH and SCD.
  • At similar distances, genotype (chromosome) alterations of surrounding bronchial mucosa were studied in additional 55 primary and secondary lung tumors by karyotype analysis.
  • Losses of y chromosome were seen in both malignancy and adjacent bronchial mucosa, and interpreted as "tumor related", losses of chromosome 21 in adjacent bronchial mucosa were non-tumor related in adenocarcinoma and metastases, losses of chromosome 19 in adjacent bronchial mucosa occurred independently in squamous cell and large cell carcinomas.
  • The data suggest the hypothesis that preneoplastic lesions in the lung might be partly induced by the tumor itself.

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  • (PMID = 15639719.001).
  • [ISSN] 0169-5002
  • [Journal-full-title] Lung cancer (Amsterdam, Netherlands)
  • [ISO-abbreviation] Lung Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
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20. Bhatt S, Rubens DJ, Dogra VS: Sonography of benign intrascrotal lesions. Ultrasound Q; 2006 Jun;22(2):121-36
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  • [Title] Sonography of benign intrascrotal lesions.
  • Ultrasound plays an important role and adds essential information in diagnosing benign intrascrotal lesions.
  • Characterization of benign intrascrotal lesions with sonography, in combination with clinical assessment, can lead to nonsurgical management or testicular sparing surgery.
  • We present important sonographic features of benign intrascrotal lesions, including extratesticular lesions: adenomatoid tumors, papillary cystadenomas, spermatoceles, hydroceles, varicoceles, hernias; and intratesticular lesions: tunica albuginea cysts, testicular simple cysts, epidermoid cysts, tubular ectasia of the rete testis, intratesticular varicoceles, adrenal rest tumors, and splenogonadal fusion.
  • The goal of this review is to provide the radiologist with a better understanding of benign lesions that occur in the scrotum.

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  • (PMID = 16783242.001).
  • [ISSN] 0894-8771
  • [Journal-full-title] Ultrasound quarterly
  • [ISO-abbreviation] Ultrasound Q
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 73
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21. Tsolakis AV, Stridsberg M, Grimelius L, Portela-Gomes GM, Falkmer SE, Waldum HL, Janson ET: Ghrelin immunoreactive cells in gastric endocrine tumors and their relation to plasma ghrelin concentration. J Clin Gastroenterol; 2008 Apr;42(4):381-8
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  • [Title] Ghrelin immunoreactive cells in gastric endocrine tumors and their relation to plasma ghrelin concentration.
  • GOALS: Our aim was to elucidate the incidence and distribution pattern of ghrelin-immunoreactive (IR) cells in various types of human gastric endocrine tumors, and their surrounding mucosa, and relate the findings to total ghrelin concentrations in plasma.
  • STUDY: Forty-eight gastric endocrine tumors were included in the study: 32 type I ECL-CCs, 3 type II, 9 type III, 1 non-ECL-CC, and 3 poorly differentiated endocrine carcinomas.
  • The tumors were analyzed immunohistochemically with antibodies raised versus chromogranin A, synaptophysin, serotonin, somatostatin, vesicular monoamine transporter 2 and ghrelin.
  • RESULTS: Ghrelin-IR cells were found in all types I and II ECL-CCs but in only a few cases of the other tumors.
  • Ghrelin-IR cells were also found among the hyperplastic endocrine cells in the mucosa surrounding types I and II, where they showed diffuse, linear, nodular and adenomatoid hyperplasia patterns.
  • [MeSH-major] Antibodies, Neoplasm / immunology. Carcinoid Tumor / immunology. Gastric Mucosa / pathology. Ghrelin / immunology. Stomach Neoplasms / immunology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biomarkers, Tumor. Female. Humans. Hyperplasia. Immunohistochemistry. Male. Middle Aged. Prognosis. Radioimmunoassay. Severity of Illness Index

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  • (PMID = 18277901.001).
  • [ISSN] 0192-0790
  • [Journal-full-title] Journal of clinical gastroenterology
  • [ISO-abbreviation] J. Clin. Gastroenterol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Neoplasm; 0 / Biomarkers, Tumor; 0 / Ghrelin
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22. Chang Q, Zhu X, Zhong YF, Ma M: Adenomatoid tumor of the suprarenal region with high plasma adrenocorticotropic hormone: a case report. Chin Med J (Engl); 2009 Nov 5;122(21):2678-80
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  • [Title] Adenomatoid tumor of the suprarenal region with high plasma adrenocorticotropic hormone: a case report.
  • [MeSH-major] Adenomatoid Tumor / blood. Adenomatoid Tumor / diagnosis. Adrenocorticotropic Hormone / blood

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  • (PMID = 19951594.001).
  • [ISSN] 0366-6999
  • [Journal-full-title] Chinese medical journal
  • [ISO-abbreviation] Chin. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 9002-60-2 / Adrenocorticotropic Hormone
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23. Koren J, Cunderlík P: [Adenomatoid tumor of the right adrenal gland: a case report]. Cesk Patol; 2005 Jul;41(3):111-4
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  • [Title] [Adenomatoid tumor of the right adrenal gland: a case report].
  • [Transliterated title] Adenomatoidný tumor pravej nadoblicky: kazuistika.
  • Adenomatoid tumor of adrenal gland is a very rare primary tumor with favourable prognosis.
  • The mesothelial origin of this tumor was confirmed by multiple studies of various authors.
  • In our case report, we present an interesting case of the adenomatoid tumor of the right adrenal gland in a 55-year-old woman.
  • Our case is the second well-documented case of this tumor occurring in a female adult patient.
  • We emphasize the presence of an intraluminal thread-like bridging strands, generally considered to be a characteristic histologic feature of this tumor, which have not yet been reported in literature in adenomatoid tumor located in adrenal glands.
  • [MeSH-major] Adenomatoid Tumor / pathology. Adrenal Gland Neoplasms / pathology

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  • (PMID = 16161457.001).
  • [ISSN] 1210-7875
  • [Journal-full-title] Československá patologie
  • [ISO-abbreviation] Cesk Patol
  • [Language] slo
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Czech Republic
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24. Gupta R, Howell RS, Amin MB: Paratesticular paraganglioma: a rare cause of an intrascrotal mass. Arch Pathol Lab Med; 2009 May;133(5):811-3
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  • We describe a case of a paratesticular paraganglioma in a 33-year-old man who presented with a scrotal mass and underwent a right testicular exploration.
  • Metastasis is the only definite criterion for diagnosis of a malignant paraganglioma; however, lymphovascular invasion was noted in this case, which warranted a close clinical surveillance.
  • The patient is currently well with no evidence of disease 18 months after radical orchiectomy.
  • Paratesticular paragangliomas are extremely rare tumors with 6 cases reported in English literature.
  • The histogenesis of these tumors is unknown.
  • Though the histology and immunohistochemistry resemble those of paragangliomas at any other location, these tumors raise a plethora of differential diagnoses especially with the more commonly occurring tumors.
  • [MeSH-minor] Adenomatoid Tumor / diagnosis. Adult. Biomarkers, Tumor / analysis. Diagnosis, Differential. Disease-Free Survival. Humans. Male. Mesothelioma / diagnosis. Neuroectodermal Tumor, Melanotic / diagnosis. Treatment Outcome

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  • (PMID = 19415959.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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25. Kayser K, Kosjerina Z, Goldmann T, Kayser G, Kazmierczak B, Vollmer E: Phenotype and genotype associations of lung carcinoma with atypical adenomatoid hyperplasia, squamous cell dysplasia, and chromosome alterations in non-neoplastic bronchial mucosa. Rom J Morphol Embryol; 2005;46(1):5-10
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  • [Title] Phenotype and genotype associations of lung carcinoma with atypical adenomatoid hyperplasia, squamous cell dysplasia, and chromosome alterations in non-neoplastic bronchial mucosa.
  • To investigate the contemporary manifestation of lung cancer precursor lesions, peripheral (non-neoplastic) lung parenchyma and bronchial mucosa of operated lung carcinomas were analyzed at distinct distances (1, 2, 3, and 4 cm) from the tumor boundary for pre-neoplastic lesions--atypical adenomatoid hyperplasia (AAH) and squamous cell dysplasia (SCD), in 150 surgical specimens.
  • Short-term tissue cultures of additional 55 primary and secondary lung tumors and their surrounding non-neoplastic bronchial mucosa were performed at the same distances in order to search for chromosome alterations, i.e. genotype aberrations.
  • In phenotype observations, atypical adenomatoid hyperplasia was noted in 19/150 (13%) cases, and squamous cell dysplasia in 46/150 (31%) cases.
  • The degree of cellular atypia decreased with increasing distance from the tumor boundary in both AAH and SCM.
  • Data indicate that the so-called preneoplastic lesions in the lung are not completely tumor-precursor lesions, but, in addition, induced by the tumor itself.

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  • (PMID = 16286978.001).
  • [ISSN] 1220-0522
  • [Journal-full-title] Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
  • [ISO-abbreviation] Rom J Morphol Embryol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Romania
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26. Cakir C, Gulluoglu MG, Yilmazbayhan D: Cell proliferation rate and telomerase activity in the differential diagnosis between benign and malignant mesothelial proliferations. Pathology; 2006 Feb;38(1):10-5
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  • [Title] Cell proliferation rate and telomerase activity in the differential diagnosis between benign and malignant mesothelial proliferations.
  • AIMS: The differential diagnosis of malignant mesothelioma (MM) from benign mesothelial lesions (BML) based on histopathological criteria is sometimes not satisfying and causes diagnostic problems for histopathologists.
  • METHODS: Sixty-six cases of MM (33 epithelioid, 30 biphasic and 3 sarcomatoid) and 22 cases of BML (15 reactive mesothelial proliferations and 7 fibrous pleuritis/pericarditis) were included in this study.
  • CONCLUSION: As a result, being cheap and simple methods, Ki-67 and hTERT immunohistochemistries can be used in differentiating malignant and benign mesothelial lesions in routine formalin-fixed, paraffin-embedded material.
  • [MeSH-major] Cell Proliferation. Neoplasms, Mesothelial / metabolism. Neoplasms, Mesothelial / pathology. Telomerase / metabolism
  • [MeSH-minor] Adult. Aged. Biomarkers, Tumor / metabolism. DNA-Binding Proteins / metabolism. Diagnosis, Differential. Female. Humans. Hyperplasia / pathology. Immunohistochemistry. Ki-67 Antigen / metabolism. Male. Middle Aged. Pleurisy / diagnosis. Pleurisy / metabolism. Pleurisy / pathology. Predictive Value of Tests. Sensitivity and Specificity

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  • (PMID = 16484001.001).
  • [ISSN] 0031-3025
  • [Journal-full-title] Pathology
  • [ISO-abbreviation] Pathology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA-Binding Proteins; 0 / Ki-67 Antigen; EC 2.7.7.49 / Telomerase
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27. Manjunath GV, Nandini NM, Sunila: Fine needle aspiration cytology of adenomatoid tumour--a case report with review of literature. Indian J Pathol Microbiol; 2005 Oct;48(4):503-4
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  • [Title] Fine needle aspiration cytology of adenomatoid tumour--a case report with review of literature.
  • Adenomatoid tumours are neoplasms of male and female genital tract with the epididymis being the most common site.
  • These benign tumours are asymptomatic or cause mild symptoms and a palpable mass.
  • Fine needle aspiration of these tumours is very useful to differentiate malignant from benign lesions and helps to avoid unnecessary aggressive surgical procedures.
  • FNAC of these benign epididymal tumours is diagnostic, rapid, reliable, conclusive and cost effective.
  • We are reporting a case of adenomatoid tumour of epididymis in a 41 year old male patient, diagnosed by FNAC and confirmed by histopathology.
  • [MeSH-major] Adenomatoid Tumor / pathology. Epididymis. Genital Neoplasms, Male / pathology

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  • (PMID = 16366111.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] India
  • [Number-of-references] 7
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28. de Medeiros AM, Nonaka CF, Galvão HC, de Souza LB, Freitas Rde A: Expression of extracellular matrix proteins in ameloblastomas and adenomatoid odontogenic tumors. Eur Arch Otorhinolaryngol; 2010 Feb;267(2):303-10
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  • [Title] Expression of extracellular matrix proteins in ameloblastomas and adenomatoid odontogenic tumors.
  • This study evaluated the expression of fibronectin, tenascin and type I collagen in ameloblastomas and adenomatoid odontogenic tumors (AOTs) aiming to contribute with the comprehension of the differences in the biological behavior of these tumors.
  • All tumors presented moderate fibronectin expression in the stroma.
  • Solid ameloblastomas showed intense expression of fibronectin at the epithelial-mesenchymal interface, whereas desmoplastic ameloblastomas revealed no immunoexpression of fibronectin at this site.
  • Ameloblastomas presented stronger immunoreactivity to tenascin than AOTs, especially at the epithelial-mesenchymal interface.
  • [MeSH-major] Adenomatoid Tumor / metabolism. Ameloblastoma / metabolism. Collagen Type I / biosynthesis. Fibronectins / biosynthesis. Jaw Neoplasms / metabolism. Odontogenic Tumors / metabolism. Tenascin / biosynthesis
  • [MeSH-minor] Biomarkers, Tumor / biosynthesis. Extracellular Matrix Proteins / biosynthesis. Humans. Immunohistochemistry. Prognosis

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  • [Cites] Int J Biochem Cell Biol. 2004 Jun;36(6):986-90 [15094113.001]
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  • (PMID = 19466441.001).
  • [ISSN] 1434-4726
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Collagen Type I; 0 / Extracellular Matrix Proteins; 0 / Fibronectins; 0 / Tenascin
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29. Bestard Vallejo JE, Tremps Velázquez E, Blázquez Mañá C, Celma Doménech A, de Torres Ramírez I, Morote Robles J: [Adenomatoid tumour of epididymis: the most common tumour of the paratesticular structures]. Actas Urol Esp; 2008 Jun;32(6):611-7
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  • [Title] [Adenomatoid tumour of epididymis: the most common tumour of the paratesticular structures].
  • [Transliterated title] Tumor adenomatoide de epididimo: el tumor más frecuente de las estructuras paratesticulares.
  • INTRODUCTION: Paratesticular tumours are rare but generally benign neoplasms, usually treated by local excission.
  • Adenomatoid tumours of epididymis are the most common of these tumours.
  • OBJECTIVES: Analyze paratesticular tumours treated in our center and describe dyagnosis and treatment of adenomatoid tumours of epididymis.
  • MATERIAL AND METHODS: We retrospectively review 8 patients with paratesticular tumours treated from July 1997 to July 2007.
  • RESULTS: Patients median age was 44.1 years (22-69), presenting most of them subacute scrotal tumour with median size by ultrasound of 2.8 cm (1.5-7).
  • All of them were locally extirpated except one with suspicion of a malignant polyorchidism and another one with an apparently intratesticular lesion of great size.
  • Dyagnosis was in 4 cases adenomatoid tumour of epididymis, in two cases fibrous pseudotumour of epididymis, in one case leiomyoma of epididymis and in one case angiolipoma of spermatic cord.
  • Just in one case diagnosed of adenomatoid tumour of epididymis ultrasound confirmed solid tumour suggesting the final dyagnosis.
  • CONCLUSIONS: Adenomatoid tumors of epididymis are rare tumours which may present at any age.
  • Benignity of adenomatoid tumour of epididymis as well as most of the other paratesticular tumours should make local excission the treatment of choice and, when any doubt existed, peroperatory biopsy should be performed.
  • [MeSH-major] Adenomatoid Tumor. Epididymis. Genital Neoplasms, Male

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  • (PMID = 18655344.001).
  • [ISSN] 0210-4806
  • [Journal-full-title] Actas urologicas españolas
  • [ISO-abbreviation] Actas Urol Esp
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 19
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30. Kalyani R, Das S: Adenomatatoid tumor: Cytological diagnosis of two cases. J Cytol; 2009 Jan;26(1):30-2
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  • [Title] Adenomatatoid tumor: Cytological diagnosis of two cases.
  • Adenomatoid tumor is a benign neoplasm of mesothelial cell origin that occurs in both male and female genital tracts.
  • Fine needle aspiration cytology has an important role in the preoperative diagnosis of the male genital adenomatoid tumor and is a rapid, reliable, conclusive, and cost-effective diagnostic tool that can be used to take appropriate surgical decisions.

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  • [Cites] Acta Cytol. 1999 May-Jun;43(3):495-7 [10349389.001]
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  • (PMID = 21938146.001).
  • [ISSN] 0970-9371
  • [Journal-full-title] Journal of cytology
  • [ISO-abbreviation] J Cytol
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3167987
  • [Keywords] NOTNLM ; Adenomatoid tumor / FNAC / epididymis / testis
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31. Pila Pérez R, Rosales Torres P, Pila Peláez R, Holguín Prieto V, Torres Vargas E: [Adenomatoid tumor of the epididymis: an infrequent case]. Arch Esp Urol; 2009 Oct;62(8):656-60
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  • [Title] [Adenomatoid tumor of the epididymis: an infrequent case].
  • [Transliterated title] Tumor adenomatoide del epidídimo: una infrecuente observación.
  • OBJECTIVES: To present a new case of adenomatoid tumor of the epididymis, the first report in our hospital since 1962.
  • METHODS: We report a clinical case with a brief bibliographic review about adenomatoid tumor of the epididymis.
  • Physical examination and ultrasound study demonstrated a tumor of 5x5x2 cm.
  • It was removed and the histopathological study was compatible with adenomatoid tumor of the epididymis.
  • CONCLUSION: The adenomatoid tumor of the epididymis is a neoplasm located in the paratesticular region, however it can be found infrequently in other sites.
  • Mesothelial origin has been mentioned and inflammation has played some role in the development of these tumors.
  • It can minimally invade adjacent structures, though it is benign without metastatic potential.
  • [MeSH-major] Adenomatoid Tumor. Epididymis. Genital Neoplasms, Male

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  • (PMID = 19893140.001).
  • [ISSN] 1576-8260
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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32. Vacharadze K, Burkadze G, Turashvili G, Kiria N: Argyrophilic nucleolar organizer regions in benign and malignant mesothelial lesions. Georgian Med News; 2005 Nov;(128):91-3
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  • [Title] Argyrophilic nucleolar organizer regions in benign and malignant mesothelial lesions.
  • The aim our study was to assess the usefulness of AgNOR stain in distinguishing between benign and malignant mesothelial lesions.
  • The patients were divided into three groups: group I -- reactive mesothelium (71 cases), group II -- hyperplastic mesothelium (66 cases), group III -- epithelial type mesothelioma (52 cases).
  • Our results show that AgNOR staining is useful to differentiate epithelial type mesothelioma and benign mesothelial lesions such as reactive and hyperplastic mesothelium.
  • AgNOR is highly sensitive, specific and cost-effective technology which can be used as an ancillary diagnostic approach for distinguishing between reactive and/or hyperplastic changes of mesothelium as well as in differential diagnosis of epithelial type mesothelioma.
  • [MeSH-major] Antigens, Nuclear / metabolism. Lung Diseases / metabolism. Lung Diseases / pathology. Neoplasms, Mesothelial / metabolism. Neoplasms, Mesothelial / pathology. Nuclear Proteins / metabolism

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  • (PMID = 16369075.001).
  • [ISSN] 1512-0112
  • [Journal-full-title] Georgian medical news
  • [ISO-abbreviation] Georgian Med News
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Georgia (Republic)
  • [Chemical-registry-number] 0 / Antigens, Nuclear; 0 / Nuclear Proteins; 0 / nucleolar organizer region associated proteins
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33. Kallel R, Ayadi L, Gouiaa N, Chaabouni S, Karray F, Daoud E, Chaari C, Khabir A, Makni S, Boudawara T: [Extrafollicular adenomatoid odontogenic tumour: report of two cases]. Rev Med Brux; 2009 Sep-Oct;30(5):511-4
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  • [Title] [Extrafollicular adenomatoid odontogenic tumour: report of two cases].
  • [Transliterated title] Tumeur odontogène adénomatoïde extrafolliculaire: à propos de deux cas.
  • The purpose of this study was to analysis the clinicopathological features of adenomatoid odontogenic tumour extrafollicular and to discuss the diagnosis pitfull.
  • An exploratory surgical approach was chosen and the final diagnosis was microscopically confirmed to be an extrafollicular variant of adenomatoid odontogenic tumour.
  • The two cases described illustrate clinical and radiographic features of the extrafollicular variant of adenomatoid odontogenic tumour.
  • [MeSH-major] Mandibular Neoplasms / radiography. Odontogenic Tumors / radiography

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  • (PMID = 19998797.001).
  • [ISSN] 0035-3639
  • [Journal-full-title] Revue médicale de Bruxelles
  • [ISO-abbreviation] Rev Med Brux
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Belgium
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34. Bierry G, Riehm S, Marcellin L, Stierlé JL, Veillon F: Middle ear adenomatous tumor: a not so rare glomus tympanicum-mimicking lesion. J Neuroradiol; 2010 May;37(2):116-21
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  • [Title] Middle ear adenomatous tumor: a not so rare glomus tympanicum-mimicking lesion.
  • BACKGROUND AND PURPOSE: Middle ear adenomatous tumors (MEAT) are rare tumors which can be begin or malignant and can present a neuroendocrine differentiation.
  • Tumor location, size, extension, signal intensity, and enhancement were analysed.
  • A close relationship between the tumor and the Jacobson's nerve or its branches was identified in all cases of GT.
  • [MeSH-major] Adenomatoid Tumor / diagnosis. Ear Neoplasms / diagnosis. Ear, Middle / pathology. Glomus Tympanicum Tumor / diagnosis

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  • [Copyright] Copyright 2009 Elsevier Masson SAS. All rights reserved.
  • (PMID = 19573921.001).
  • [ISSN] 0150-9861
  • [Journal-full-title] Journal of neuroradiology. Journal de neuroradiologie
  • [ISO-abbreviation] J Neuroradiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] France
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35. Lehsnau M, Hecht L: [Adenomatoid tumor of the testes--a rare entity. Clinical, diagnostic and therapeutic aspects]. Urologe A; 2006 Nov;45(11):1431-4
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  • [Title] [Adenomatoid tumor of the testes--a rare entity. Clinical, diagnostic and therapeutic aspects].
  • [Transliterated title] Adenomatoidtumor des Hodens--eine seltene Entität. Klinische, diagnostische und therapeutische Aspekte.
  • Adenomatoid tumor with intra-testicular localization is rare.
  • Adenomatoid tumors occur in both sexes and are also found in the uterus, ovary and fallopian tubes of the female genital tract.
  • Adenomatoid tumors are benign proliferations of mesothelial origin.
  • We report the case of a 50-year-old male with an adenomatoid tumor of the left testis.
  • [MeSH-major] Adenomatoid Tumor / diagnosis. Testicular Neoplasms / diagnosis
  • [MeSH-minor] Biomarkers, Tumor / analysis. Biopsy. Calbindin 2. Diagnosis, Differential. Humans. Keratins / analysis. Male. Middle Aged. Orchiectomy. Prognosis. S100 Calcium Binding Protein G / analysis. Testis / pathology. Tomography, X-Ray Computed. Ultrasonography. Vimentin / analysis

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  • (PMID = 16933122.001).
  • [ISSN] 0340-2592
  • [Journal-full-title] Der Urologe. Ausg. A
  • [ISO-abbreviation] Urologe A
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Calbindin 2; 0 / S100 Calcium Binding Protein G; 0 / Vimentin; 68238-35-7 / Keratins
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36. Garriga V, Serrano A, Marin A, Medrano S, Roson N, Pruna X: US of the tunica vaginalis testis: anatomic relationships and pathologic conditions. Radiographics; 2009 Nov;29(7):2017-32
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  • Most lesions originate from or depend on the tunica vaginalis, a mesothelium-lined sac with a visceral layer and a parietal layer.
  • Lesions of mesothelial origin, such as adenomatoid tumor, tunica cyst, and mesothelioma, may involve the tunica vaginalis.
  • Entrapped mesenchymal cells can lead to lipoma, leiomyoma, or sarcoma, although these tumors are uncommon in the tunica vaginalis.
  • US is not useful for differentiating between benign and malignant tumors; however, some characteristic findings may help in planning the best surgical approach.

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  • (PMID = 19926760.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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37. Poomsawat S, Punyasingh J, Vejchapipat P: Expression of basement membrane components in odontogenic tumors. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2007 Nov;104(5):666-75
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  • [Title] Expression of basement membrane components in odontogenic tumors.
  • OBJECTIVE: The objective was to characterize the expression of BMCs (laminins 1 and 5, collagen type IV, and fibronectin) in ameloblastomas, calcifying cystic odontogenic tumors (CCOTs), and adenomatoid odontogenic tumors (AOTs).
  • RESULTS: In normal oral mucosa, linear deposits of these proteins were found at the epithelial-mesenchymal junction, but not in epithelial cytoplasm.
  • In all tumors studied, linear deposits of all proteins were found at the epithelial-mesenchymal junction; laminin 1 was expressed in all tumor cells, regardless of cell types.
  • For AOTs, laminin 5 strongly decorated tumor cells adjacent to mineralization.
  • [MeSH-major] Ameloblastoma / pathology. Basement Membrane / pathology. Jaw Neoplasms / pathology. Odontogenic Cyst, Calcifying / pathology. Odontogenic Tumors / pathology

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  • (PMID = 17150384.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cell Adhesion Molecules; 0 / Collagen Type IV; 0 / Fibronectins; 0 / Laminin; 0 / kalinin; 0 / laminin 1
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38. Ghossain MA, Chucrallah A, Kanso H, Aoun NJ, Abboud J: Multilocular adenomatoid tumor of the ovary: ultrasonographic findings. J Clin Ultrasound; 2005 Jun;33(5):233-6
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  • [Title] Multilocular adenomatoid tumor of the ovary: ultrasonographic findings.
  • We report the sonographic findings of a rare benign ovarian tumor in a 69-year-old woman.
  • Surgery revealed an adenomatoid tumor.
  • Adenomatoid tumors are benign lesions of mesothelial origin, usually solid in nature and rarely located in the ovaries. (c) 2005 Wiley Periodicals, Inc.
  • [MeSH-major] Adenomatoid Tumor / ultrasonography. Ovarian Neoplasms / ultrasonography

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  • [Copyright] (c) 2005 Wiley Periodicals, Inc. J Clin Ultrasound 33:233-236, 2005.
  • (PMID = 16047378.001).
  • [ISSN] 0091-2751
  • [Journal-full-title] Journal of clinical ultrasound : JCU
  • [ISO-abbreviation] J Clin Ultrasound
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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39. Nagata S, Aishima S, Fukuzawa K, Takagi H, Yonemasu H, Iwashita Y, Kinoshita T, Wakasugi K: Adenomatoid tumour of the liver. J Clin Pathol; 2008 Jun;61(6):777-80
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  • [Title] Adenomatoid tumour of the liver.
  • An unusual primary adenomatoid tumour arising in the normal liver is described.
  • Hepatectomy was performed, and the patient is alive and free of disease 1 year postsurgery.
  • Grossly, the tumour showed a haemorrhagic cut surface with numerous microcystic structures.
  • Immunohistochemical studies showed that the epithelioid cells were strongly positive for a broad spectrum of cytokeratins (AE1/AE3, CAM5.2, epithelial membrane antigen and cytokeratin 7) and mesothelial markers (calretinin, Wilms' tumour 1 and D2-40).
  • Atypically, abundant capillaries were observed; however, the cystic proliferation of epithelioid cells with vacuoles and immunohistochemical profile of the epithelioid element were consistent with hepatic adenomatoid tumour.
  • [MeSH-major] Adenomatoid Tumor / pathology. Liver Neoplasms / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Calbindin 2. Hepatectomy. Humans. Immunohistochemistry. Keratins / analysis. Male. Neovascularization, Pathologic. S100 Calcium Binding Protein G / analysis. Tomography, X-Ray Computed

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  • (PMID = 18505892.001).
  • [ISSN] 1472-4146
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CALB2 protein, human; 0 / Calbindin 2; 0 / S100 Calcium Binding Protein G; 68238-35-7 / Keratins
  • [Other-IDs] NLM/ PMC2569191
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40. Pich A, Galliano D: Pure (non-papillary) serous cystadenoma of the epididymis: a histologic and immunohistochemical study. Pathol Res Pract; 2005;201(1):65-9
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  • A cystic tumor strictly attached to the head of the epididymis was surgically resected.
  • Immunohistochemical staining was positive for epithelial membrane antigen, low- and high molecular weight cytokeratins, progesterone receptor, vimentin, and S-100 protein, but was negative for carcinoembryonic antigen, CD10, p53 protein, and calretinin.
  • The differential diagnosis to spermatocele and adenomatoid tumor of the epididymis is discussed.

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  • (PMID = 15807314.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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41. Gupta B, Ponniah I: The pattern of odontogenic tumors in a government teaching hospital in the southern Indian state of Tamil Nadu. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Jul;110(1):e32-9
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  • [Title] The pattern of odontogenic tumors in a government teaching hospital in the southern Indian state of Tamil Nadu.
  • OBJECTIVE: This hospital-based study was designed to provide demographic data on odontogenic tumors from the southern Indian population in the state of Tamil Nadu for comparison with pertinent series from other geographic regions.
  • STUDY DESIGN: A total of 489 cases of odontogenic tumors registered over a period of 38 years (February 1970-March 2008) in the Department of Oral and Maxillofacial Pathology of Tamil Nadu Government Dental College and Hospital, Chennai, India, were retrieved from the files of histopathology registers and were retrospectively analyzed.
  • RESULTS: Odontogenic tumors in the present study constituted 4.13% of all the 11,843 registered biopsies.
  • Ameloblastoma with a predilection for posterior mandible was the most frequent odontogenic tumor (67.69%), followed by adenomatoid odontogenic tumor (9%), odontoma (7.77%), and calcifying odontogenic cyst (5.52%).
  • CONCLUSION: The relative frequency of 4.13% of odontogenic tumors observed in this study, which is the largest series from this part of the world.
  • Ameloblastoma formed the single most common tumor of all odontogenic tumors.
  • This study observed both regional and geographic variations in the frequency and distribution of odontogenic tumors.
  • [MeSH-major] Odontogenic Tumors / epidemiology

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  • [Copyright] Copyright (c) 2010 Mosby, Inc. All rights reserved.
  • (PMID = 20610293.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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42. Bandier PC, Hansen A, Thorelius L: [Adenomatoid tumour of the adrenal gland]. Ugeskr Laeger; 2009 Jan 26;171(5):306-8
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  • [Title] [Adenomatoid tumour of the adrenal gland].
  • [Transliterated title] Adenomatoid tumor i binyre.
  • An adenomatoid tumour in the right suprarenal gland was discovered during clinical cancer staging of a 73-year-old woman.
  • Adenomatoid tumours in the suprarenal glands are rare and are most often found incidentally.
  • Differential diagnoses comprise malignant vascular neoplasm or adenocarcinoma.
  • Immunohistochemistry or electron microscopy allows uncomplicated distinction between these tumours.
  • [MeSH-major] Adenomatoid Tumor / pathology. Adrenal Gland Neoplasms / pathology

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  • [CommentIn] Ugeskr Laeger. 2009 Mar 16;171(12):1015; author reply 1015 [19306484.001]
  • (PMID = 19176156.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Denmark
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43. Serrano Frago P, Medrano Llorente P, Borque Fernando A, Pascual Llorente M, Allue López M: [Consults by scrotum mass: epididymo lesions]. Actas Urol Esp; 2007 Apr;31(4):420-2
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  • In this review we try to update the knowledge about the tumors of epididymis, describing problems in diagnosis and treatment.
  • We present a case of a 39 years old patient who consults by left testicular mass, before the sonogarphy suspect of tumor was made magnetic resonance imaging , wich aimed towards tumorlike injury.
  • Excision of the injury via inguinal was made and the pathologic diagnosis was of adenomatoid tumor.
  • Owing to the few series that appear in literature, and being the commentaries of these tumors about isolated cases, we expose the characteristics of this illustrated case to value the characteristics in diagnosis and treatment to compare them with other cases.
  • [MeSH-major] Adenomatoid Tumor / diagnosis. Epididymis. Genital Neoplasms, Male / diagnosis. Scrotum

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  • (PMID = 17633931.001).
  • [ISSN] 0210-4806
  • [Journal-full-title] Actas urologicas españolas
  • [ISO-abbreviation] Actas Urol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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44. Varkarakis IM, Mufarrij P, Studeman KD, Jarrett TW: Adenomatoid of the adrenal gland. Urology; 2005 Jan;65(1):175
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  • [Title] Adenomatoid of the adrenal gland.
  • Adenomatoid tumors are common in the genital tract but rare in the adrenal gland.
  • These tumors can be difficult to diagnose when present in extragenital sites.
  • This type of adrenal tumor lacks specific radiographic features and can be confused preoperatively with more common adrenal gland tumors.
  • We present the case of a 54-year-old man with an incidental right adrenal mass with calcified components and elevated urinary levels of homovanillic acid that was found to be an adenomatoid tumor of the adrenal gland.
  • [MeSH-major] Adenomatoid Tumor / radiography. Adrenal Gland Neoplasms / radiography. Calcinosis / radiography
  • [MeSH-minor] Biomarkers, Tumor / analysis. Calbindin 2. Homovanillic Acid / urine. Humans. Incidental Findings. Kidney Calculi / complications. Kidney Calculi / radiography. Male. Middle Aged. Neoplasm Proteins / analysis. S100 Calcium Binding Protein G / analysis

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  • (PMID = 15667895.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Calbindin 2; 0 / Neoplasm Proteins; 0 / S100 Calcium Binding Protein G; X77S6GMS36 / Homovanillic Acid
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45. Shima M, Takahashi S, Maeda T, Masumori N, Itoh N, Tsukamoto T: [Adenomatoid tumor of the testis with testicular pain: a case report]. Hinyokika Kiyo; 2009 May;55(5):285-6
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  • [Title] [Adenomatoid tumor of the testis with testicular pain: a case report].
  • The intraoperative findings showed a small, white, elastic solid, a smooth surface tumor that originated from the tunica albuginea of the right testis.
  • It seemed to be benign macroscopically and partial orchiectomy was performed.
  • Pathohistological examination revealed an adenomatoid tumor of the testis which originated from the rete testis.
  • Adenomatoid tumor of the testis is a rare benign tumor.
  • Therefore, we should be aware that an adenomatoid tumor of the testis can be one of the differential diagnoses of acute scrotum.
  • [MeSH-major] Adenomatoid Tumor / complications. Adenomatoid Tumor / surgery. Pain / etiology. Scrotum. Testicular Neoplasms / complications. Testicular Neoplasms / surgery
  • [MeSH-minor] Acute Disease. Adult. Diagnosis, Differential. Humans. Male. Orchiectomy

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  • (PMID = 19507549.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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46. Ide F, Mishima K, Saito I, Kusama K: Rare peripheral odontogenic tumors: report of 5 cases and comprehensive review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2008 Oct;106(4):e22-8
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  • [Title] Rare peripheral odontogenic tumors: report of 5 cases and comprehensive review of the literature.
  • Peripheral odontogenic tumor (POT) is a rarely encountered lesion.
  • We report 5 cases of POT including adenomatoid odontogenic tumor (AOT), keratocystic odontogenic tumor (KCOT), ameloblastic fibroma (AF), developing odontoma (DO), and calcifying cystic odontogenic tumor (CCOT), and also provide a review of relevant literature to define the tumor profile.
  • [MeSH-major] Mandibular Neoplasms / pathology. Maxillary Neoplasms / pathology. Odontogenic Tumors / pathology

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  • (PMID = 18718792.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 44
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47. Taheri ZM, Mehrafza M, Mohammadi F, Khoddami M, Bahadori M, Masjedi MR: The diagnostic value of Ki-67 and repp86 in distinguishing between benign and malignant mesothelial proliferations. Arch Pathol Lab Med; 2008 Apr;132(4):694-7
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  • [Title] The diagnostic value of Ki-67 and repp86 in distinguishing between benign and malignant mesothelial proliferations.
  • CONTEXT: The differentiation of benign mesothelial proliferations from malignant mesotheliomas may be difficult, especially when evaluating small specimens from pleural biopsies.
  • OBJECTIVE: To explore the potential value of 2 proliferative cell markers, Ki-67 and restrictedly expressed proliferation-associated protein 86 kDa (repp86), in distinguishing between malignant mesothelioma (MM) and benign reactive mesothelial hyperplasia (MH).
  • DESIGN: Thirty-six cases of MM from 26 men and 10 women with a mean age of 62.9 years (range, 36-80 years) and 22 cases of benign reactive MH from 14 male and 8 female patients with a mean age of 51.5 years (range, 15- 88 years) were included in this study.
  • RESULTS: The mean labeling indexes for Ki-67 in MM and benign reactive MH were 24.6% (range, 1%-66%) and 6.23% (range, 0%-25%), respectively.
  • The mean labeling indexes for repp86 in MM and benign reactive MH were 26.3% (range, 0%-50%) and 3.26% (range, 0%- 21%), respectively.
  • The average proliferative cell count was significantly higher in MM compared with benign reactive MH (P < .001).
  • Furthermore, both markers showed a significant correlation in their expression in MM and benign reactive MH (r = 77.5, P < .001).
  • CONCLUSIONS: Used in combination, Ki-67 and repp86 appear to be useful markers in differentiating MM from benign reactive MH.
  • [MeSH-major] Epithelium / metabolism. Ki-67 Antigen / metabolism. Mesothelioma / diagnosis. Mesothelioma / metabolism. Neoplasms, Mesothelial / diagnosis. Neoplasms, Mesothelial / metabolism. Nuclear Proteins / metabolism
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Antibodies, Monoclonal / immunology. Biomarkers / metabolism. Biomarkers, Tumor / metabolism. Cell Proliferation. Diagnosis, Differential. Female. Humans. Hyperplasia / diagnosis. Hyperplasia / metabolism. Hyperplasia / pathology. Male. Middle Aged. Sensitivity and Specificity

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  • (PMID = 18384222.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Biomarkers; 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 0 / Nuclear Proteins; 0 / SND1 protein, human
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48. Di Pierro GB, Sciarra A, Innocenzi M, Cristini C: [Rare case of multiple adenomatoid tumors arising from tunica vaginalis of testis and epididymis]. Actas Urol Esp; 2010 Jun;34(6):560-1
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  • [Title] [Rare case of multiple adenomatoid tumors arising from tunica vaginalis of testis and epididymis].
  • [Transliterated title] Raro caso de tumores adenomatoides múltiples derivados de la túnica vaginal de testículo y epidídimo.
  • [MeSH-major] Adenomatoid Tumor / pathology. Epididymis. Genital Neoplasms, Male / pathology. Neoplasms, Multiple Primary / pathology. Testicular Neoplasms / pathology

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  • (PMID = 20510121.001).
  • [ISSN] 1699-7980
  • [Journal-full-title] Actas urologicas españolas
  • [ISO-abbreviation] Actas Urol Esp
  • [Language] spa
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Spain
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49. Vasconcelos BC, Frota R, Cardoso AB, Porto GG, Carneiro SC: Adenomatoid odontogenic tumor. Braz J Otorhinolaryngol; 2008 Mar-Apr;74(2):315
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  • [Title] Adenomatoid odontogenic tumor.
  • [MeSH-major] Mandibular Neoplasms / diagnostic imaging. Maxillary Sinus Neoplasms / diagnostic imaging. Odontogenic Tumors / diagnostic imaging

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  • (PMID = 18568215.001).
  • [ISSN] 1808-8694
  • [Journal-full-title] Brazilian journal of otorhinolaryngology
  • [ISO-abbreviation] Braz J Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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50. Piccin A, Conneally E, Lynch M, McMenamin ME, Langabeer S, McCann S: Adenomatoid tumor of the testis in a patient on imatinib therapy for chronic myeloid leukemia. Leuk Lymphoma; 2006 Jul;47(7):1394-6
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  • [Title] Adenomatoid tumor of the testis in a patient on imatinib therapy for chronic myeloid leukemia.
  • [MeSH-major] Adenomatoid Tumor / diagnosis. Adenomatoid Tumor / drug therapy. Antineoplastic Agents / pharmacology. Leukemia, Myelogenous, Chronic, BCR-ABL Positive / diagnosis. Leukemia, Myelogenous, Chronic, BCR-ABL Positive / drug therapy. Piperazines / pharmacology. Pyrimidines / pharmacology. Testicular Neoplasms / diagnosis. Testicular Neoplasms / drug therapy


51. Hayes SJ, Clark P, Mathias R, Formela L, Vickers J, Armstrong GR: Multiple adenomatoid tumours in the liver and peritoneum. J Clin Pathol; 2007 Jun;60(6):722-4
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  • [Title] Multiple adenomatoid tumours in the liver and peritoneum.
  • [MeSH-major] Adenomatoid Tumor / pathology. Liver Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Peritoneal Neoplasms / pathology

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  • (PMID = 17483249.001).
  • [ISSN] 0021-9746
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1955065
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52. Farah-Klibi F, Ferchichi L, Beyâa Rassou H, Zairi I, Rameh S, Adouani A, Ben Jilani SB, Zermani R: [Adenomatoid odontogenic tumor: two cases]. Rev Stomatol Chir Maxillofac; 2007 Feb;108(1):61-4
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  • [Title] [Adenomatoid odontogenic tumor: two cases].
  • [Transliterated title] La tumeur odontogénique adénomatoïde: deux cas.
  • INTRODUCTION: Adenomatoid odontogenic tumor, initially referred to as adenoameloblastoma, is a rare and benign odontogenic tumor.
  • CASE REPORTS: We report two cases of adenomatoid odontogenic tumor, which illustrate the radiological and anatomic features of this tumor.
  • DISCUSSION: The clinical, radiological and histological features of adenomatoid odontogenic tumor are distinct from those of ameloblastoma.
  • This tumor is frequently misdiagnosed as other odontogenic cysts or tumors.
  • We discuss the anatomoclinical features and the histogenesis of this rare tumor.
  • [MeSH-major] Mandibular Neoplasms / pathology. Maxillary Neoplasms / pathology. Odontogenic Tumors / pathology

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  • (PMID = 17275864.001).
  • [ISSN] 0035-1768
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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53. van Bijsterveldt C, Willemsen W, Bulten J: Peritoneal benign mesothelioma during and after two pregnancies. Eur J Obstet Gynecol Reprod Biol; 2006 Aug;127(2):265-6
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  • [Title] Peritoneal benign mesothelioma during and after two pregnancies.
  • [MeSH-major] Mesothelioma / diagnosis. Peritoneal Neoplasms / diagnosis. Pregnancy Complications, Neoplastic / diagnosis. Pseudomyxoma Peritonei / diagnosis

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  • (PMID = 16527388.001).
  • [ISSN] 0301-2115
  • [Journal-full-title] European journal of obstetrics, gynecology, and reproductive biology
  • [ISO-abbreviation] Eur. J. Obstet. Gynecol. Reprod. Biol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Ireland
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54. Sangoi AR, McKenney JK, Schwartz EJ, Rouse RV, Longacre TA: Adenomatoid tumors of the female and male genital tracts: a clinicopathological and immunohistochemical study of 44 cases. Mod Pathol; 2009 Sep;22(9):1228-35
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  • [Title] Adenomatoid tumors of the female and male genital tracts: a clinicopathological and immunohistochemical study of 44 cases.
  • Adenomatoid tumors of the female and male genital tracts are well characterized as mesothelial in origin, but a detailed histological and immunohistochemical analysis comparing both traditional and newer mesothelial markers across gender and site has not been formally conducted.
  • A variety of morphologic features previously described as characteristic of adenomatoid tumors were evaluated in 44 adenomatoid tumors from the male and female genital tracts.
  • All (n=44) the adenomatoid tumors from both the female and male genital tracts demonstrated a distinctive thread-like bridging strand pattern.
  • Lymphoid aggregates were seen in all 12 adenomatoid tumors of male patients, but in only 4 of 32 (13%) tumors in female patients (P<0.0001).
  • The remaining morphologic features were variably present with no clear sex predilection.
  • Pankeratin, calretinin, and D2-40 reactivity were identified in all female (n=32) and male (n=12) genital tract adenomatoid tumors.
  • Adenomatoid tumors expressed WT-1 in 11/12 (92%) male patients and in 31/32 (97%) female patients.
  • In male patients, reactivity for CK5/6 and caldesmon was found in 1/12 (8%) and 0/12 (0%) adenomatoid tumors (respectively), whereas reactivity in female patients was found in 5/32 (16%) and 1/32 (3%); respectively.
  • Female tumors differ from their male counterparts by the frequent absence of lymphoid aggregates and the presence of a circumscribed margin when occurring in the fallopian tube.
  • Of the putative mesothelial markers evaluated, calretinin, D2-40, and WT-1 show a similar immunoprofile and have a higher sensitivity than CK5/6 and caldesmon in genital tract adenomatoid tumors.
  • [MeSH-major] Adenomatoid Tumor / pathology. Biomarkers, Tumor / analysis. Genital Neoplasms, Female / pathology. Genital Neoplasms, Male / pathology

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  • (PMID = 19543245.001).
  • [ISSN] 1530-0285
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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55. Füredi G, Szilágyi A, Bencsik Z, Altorjay A: [Adenomatoid tumor of the adrenal gland. Case report and review of the literature]. Orv Hetil; 2007 Aug 19;148(33):1563-5
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  • [Title] [Adenomatoid tumor of the adrenal gland. Case report and review of the literature].
  • [Transliterated title] A mellékvese adenomatoid tumora, avagy irodalmi barangolás egy igen ritka mesothelialis daganat nyomán.
  • Adenomatoid tumors of the adrenal gland are rather rare, asymptomatic neoplasias with benign behavior and usually are diagnosed incidentally.
  • The authors report a case of an adenomatoid tumor of the right adrenal gland in a 32-year-old man who sought evaluation because of fever and renal pain.
  • During investigation a tumor, localized in right adrenal gland, was identified by ultrasonography and CT.
  • The patient underwent adrenalectomy with histopathological and immunohistochemical diagnosis of adenomatoid tumor of the adrenal gland.
  • Based on literature data the epidemiology, symptoms, differential diagnosis, treatments, histopathology and prognosis of adenomatoid tumors of the adrenal gland are discussed.
  • [MeSH-major] Adenomatoid Tumor. Adrenal Gland Neoplasms
  • [MeSH-minor] Adrenalectomy. Adult. Biomarkers, Tumor / analysis. Diagnosis, Differential. Fever / etiology. Humans. Immunohistochemistry. Male. Pain / etiology. Tomography, X-Ray Computed

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  • (PMID = 17686675.001).
  • [ISSN] 0030-6002
  • [Journal-full-title] Orvosi hetilap
  • [ISO-abbreviation] Orv Hetil
  • [Language] hun
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Hungary
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 11
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56. Nortjé CJ: General practitioner's radiology case 78. Adenomatoid odontogenic tumour. SADJ; 2009 Oct;64(9):414
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  • [Title] General practitioner's radiology case 78. Adenomatoid odontogenic tumour.
  • [MeSH-major] Maxillary Neoplasms / radiography. Odontogenic Tumors / radiography

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  • (PMID = 20411838.001).
  • [ISSN] 1029-4864
  • [Journal-full-title] SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging
  • [ISO-abbreviation] SADJ
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] South Africa
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57. Weinreb I: Low grade glandular lesions of the sinonasal tract: a focused review. Head Neck Pathol; 2010 Mar;4(1):77-83
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  • While most biopsies or resections encountered routinely consist of common diagnoses such as inflammatory polyps and papillomas, occasional cases are more difficult, and separating reactive or benign from malignancy can be challenging.
  • Possible diagnoses such as reactive lesions, respiratory epithelial adenomatoid hamartoma (REAH), seromucinous (glandular) hamartoma (SH) and low grade sinonasal adenocarcinomas (LGSNAC) must be entertained.
  • REAH is composed of respiratory epithelial lined submucosal glands with variable connection to the surface and periglandular hyalinization.
  • LGSNAC is a diverse group of bland tubular and/or papillary tumors, which have a recurrence potential but an as yet uncertain potential for metastasis or mortality.
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Diagnosis, Differential. Humans. Nasal Cavity / metabolism. Nasal Cavity / pathology

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  • [Cites] Virchows Arch. 2003 Aug;443(2):152-8 [12827515.001]
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  • (PMID = 20237993.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 18
  • [Other-IDs] NLM/ PMC2825529
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58. Yeh CJ, Chuang WY, Chou HH, Jung SM, Hsueh S: Multiple extragenital adenomatoid tumors in the mesocolon and omentum. APMIS; 2008 Nov;116(11):1016-9
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  • [Title] Multiple extragenital adenomatoid tumors in the mesocolon and omentum.
  • Adenomatoid tumors are benign mesothelial neoplasms most commonly found in the male and female genital tracts.
  • Extragenital adenomatoid tumors are rare, most of them being solitary tumors.
  • To our knowledge, only one case of multiple extragenital adenomatoid tumors, involving the liver and peritoneum, has been reported to date.
  • Here we report another case of multiple extragenital adenomatoid tumors involving the mesocolon and omentum.
  • The patient was transferred to our hospital without resection due to the intraoperative finding of multiple peritoneal tumors.
  • At our hospital, an 8.0x7.5x6.0 cm tumor at the mesocolon of the sigmoid colon and three omental nodules measuring up to 2.5x2.0x1.7 cm were resected.
  • Immunohistochemically, the tumor cells were positive for pan-cytokeratin AE1/AE3, vimentin, cytokeratin 5/6 and calretinin.
  • Despite their rarity, adenomatoid tumors should be included in the differential diagnosis of multiple intra-abdominal tumors.
  • [MeSH-major] Adenomatoid Tumor / pathology. Mesocolon / pathology. Neoplasms, Multiple Primary / pathology. Omentum / pathology. Peritoneal Neoplasms / pathology

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  • (PMID = 19133002.001).
  • [ISSN] 1600-0463
  • [Journal-full-title] APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
  • [ISO-abbreviation] APMIS
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / CALB2 protein, human; 0 / Calbindin 2; 0 / S100 Calcium Binding Protein G; 0 / Vimentin; 68238-35-7 / Keratins
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59. Langer J, Cohen HL: Case 1: Diagnosis: Paratesticular adenomatoid tumor. Ultrasound Q; 2006 Jun;22(2):101-4
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  • [Title] Case 1: Diagnosis: Paratesticular adenomatoid tumor.
  • [MeSH-major] Adenomatoid Tumor / ultrasonography. Testicular Neoplasms / ultrasonography

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  • (PMID = 16783220.001).
  • [ISSN] 0894-8771
  • [Journal-full-title] Ultrasound quarterly
  • [ISO-abbreviation] Ultrasound Q
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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60. Ordóñez NG: Value of estrogen and progesterone receptor immunostaining in distinguishing between peritoneal mesotheliomas and serous carcinomas. Hum Pathol; 2005 Nov;36(11):1163-7
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  • [Title] Value of estrogen and progesterone receptor immunostaining in distinguishing between peritoneal mesotheliomas and serous carcinomas.
  • The differential diagnosis between peritoneal mesotheliomas and serous carcinomas involving the peritoneum may be difficult, but it can be facilitated by the use of immunohistochemistry.
  • To determine whether estrogen receptors (ER) or progesterone receptors (PR) may have any value as immunohistochemical markers for discriminating between these malignancies, 40 serous carcinomas of the ovary metastatic to the peritoneum, 7 primary peritoneal serous carcinomas, 30 epithelioid peritoneal malignant mesotheliomas, 5 well-differentiated papillary mesotheliomas, and 4 adenomatoid tumors were immunostained for ER and PR.
  • None of the mesotheliomas or adenomatoid tumors expressed ER or PR.
  • It is concluded that, because of its high sensitivity for serous carcinomas, ER immunostaining could be very useful in distinguishing between serous carcinomas and peritoneal mesotheliomas.
  • [MeSH-major] Biomarkers, Tumor / analysis. Cystadenocarcinoma, Serous / diagnosis. Mesothelioma / diagnosis. Peritoneal Neoplasms / diagnosis. Receptors, Estrogen / metabolism. Receptors, Progesterone / metabolism

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  • [CommentIn] Hum Pathol. 2005 Nov;36(11):1153 [16260266.001]
  • (PMID = 16260268.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
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61. Barboza CA, Pereira Pinto L, Freitas Rde A, Costa Ade L, Souza LB: Proliferating cell nuclear antigen (PCNA) and p53 protein expression in ameloblastoma and adenomatoid odontogenic tumor. Braz Dent J; 2005;16(1):56-61
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  • [Title] Proliferating cell nuclear antigen (PCNA) and p53 protein expression in ameloblastoma and adenomatoid odontogenic tumor.
  • In this study, proliferating cell nuclear antigen (PCNA) and p53 protein expressions were analyzed in 16 cases of ameloblastoma and 8 cases of adenomatoid odontogenic tumor (AOT).
  • The cases of ameloblastoma consisted of solid type tumors and histologic arrangements of different subtypes were observed.
  • In some specimens, more than one histologic subtype was identified in the same lesion, and each tumor was categorized according to the predominant cell pattern.
  • The odontogenic tumors were grouped as follows: follicular ameloblastoma (n=7), plexiform ameloblastoma (n=4), acanthomatous + follicular ameloblastoma (n=3), basal cell ameloblastoma (n=2), adenomatoid odontogenic tumor (n=8).
  • [MeSH-major] Ameloblastoma / metabolism. Odontogenic Tumors / metabolism. Proliferating Cell Nuclear Antigen / biosynthesis. Tumor Suppressor Protein p53 / biosynthesis
  • [MeSH-minor] Analysis of Variance. Humans. Immunoenzyme Techniques. Neoplasm Invasiveness. Statistics, Nonparametric

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  • (PMID = 16113935.001).
  • [ISSN] 0103-6440
  • [Journal-full-title] Brazilian dental journal
  • [ISO-abbreviation] Braz Dent J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
  • [Chemical-registry-number] 0 / Proliferating Cell Nuclear Antigen; 0 / Tumor Suppressor Protein p53
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62. Lee JC, Bhatt S, Dogra VS: Imaging of the epididymis. Ultrasound Q; 2008 Mar;24(1):3-16
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  • Ultrasonography performed with a high-frequency transducer is the modality of choice for evaluating acute and nonacute scrotal disease.
  • Features of benign and malignant epididymal lesions, including epididymal cysts, spermatoceles and tubular ectasia, sperm granulomas, adenomatoid tumors, leiomyomas, papillary cyst adenomas, lymphoma, and metastases are also presented.

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  • (PMID = 18362528.001).
  • [ISSN] 0894-8771
  • [Journal-full-title] Ultrasound quarterly
  • [ISO-abbreviation] Ultrasound Q
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 69
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63. Swasdison S, Dhanuthai K, Jainkittivong A, Philipsen HP: Adenomatoid odontogenic tumors: an analysis of 67 cases in a Thai population. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2008 Feb;105(2):210-5
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  • [Title] Adenomatoid odontogenic tumors: an analysis of 67 cases in a Thai population.
  • OBJECTIVE: The aim of this study was to determine the biologic profile of the adenomatoid odontogenic tumor (AOT) in a Thai population.
  • Age, sex, variants of AOT, site and extent of tumors, associated impacted teeth, initial clinical diagnoses, clinical presentations, and duration of symptoms were analyzed.
  • Adenomatoid odontogenic tumors were observed more often on the left side of jaws (50.7% vs. 38.8%).
  • [MeSH-major] Jaw Neoplasms / epidemiology. Jaw Neoplasms / pathology. Odontogenic Tumors / epidemiology. Odontogenic Tumors / pathology

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  • (PMID = 17613261.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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64. Tursi M, Martinetti M, Gili S, Muscio M, Gay L, Crudelini M, Cenacchi G, Pucci A: Myocardial adenomatoid tumor in eight cattle: evidence for mesothelial origin of bovine myocardial epithelial inclusions. Vet Pathol; 2009 Sep;46(5):897-903
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  • [Title] Myocardial adenomatoid tumor in eight cattle: evidence for mesothelial origin of bovine myocardial epithelial inclusions.
  • The adenomatoid tumor is an uncommon benign lesion, thus far described only in humans.
  • Adenomatoid tumors typically arise in the genital tract, exceptionally in the heart, and usually represent an incidental finding.
  • Mesothelial origin of these lesions is suggested by their immunohistochemical characteristics.
  • In cattle, previously reported myocardial epithelial inclusions are morphologically similar in that the cells are immunoreactive for both cytokeratins and vimentin, and bear surface microvilli.
  • Myocardial lesions found incidentally at slaughter in 8 cattle histologically resembled the so-called bovine myocardial epithelial inclusions and had morphologic and immunohistochemical features consistent with human adenomatoid tumor.
  • All lesions were in the left ventricular myocardium, adjacent to the epicardium, and composed of epithelioid cells that formed cords and tubules, and were immunoreactive for pan-cytokeratins, cytokeratin 5/6, vimentin, calretinin, Wilms' tumor 1 suppressor gene, and CD30 antigen.
  • The immunohistochemical and ultrastructural features were considered consistent with mesothelial origin.
  • These lesions, corresponding to the previously described myocardial epithelial inclusions in cattle, might be considered embryologic rests and could represent the bovine counterpart of the human adenomatoid tumor.
  • [MeSH-major] Adenomatoid Tumor / veterinary. Cattle Diseases / pathology. Heart Neoplasms / veterinary. Neoplasms, Mesothelial / veterinary

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  • (PMID = 19430001.001).
  • [ISSN] 1544-2217
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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65. Saghravanian N, Jafarzadeh H, Bashardoost N, Pahlavan N, Shirinbak I: Odontogenic tumors in an Iranian population: a 30-year evaluation. J Oral Sci; 2010 Sep;52(3):391-6
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  • [Title] Odontogenic tumors in an Iranian population: a 30-year evaluation.
  • Although the prevalence of odontogenic tumors varies in different geographic sites, there are no reports in English on the relative frequency of odontogenic tumors in Iran.
  • Subsequently, all lesions diagnosed as odontogenic tumors were subjected to microscopic reevaluation.
  • Among 8,766 patients, only 165 odontogenic tumors (1.9%) were found, with a mean age of 26.3 years (range 6-81 years).
  • One hundred and fifty-eight tumors were central with high frequency in the posterior region of both jaws especially in the mandible and seven were peripheral tumors, including five in the posterior mandible and two in anterior maxilla.
  • The most common tumor was ameloblastoma, followed by odontoma, odontogenic myxoma, and adenomatoid odontogenic tumor.
  • Nevertheless, odontogenic tumors occurred more in females in the third decade with affinity for the posterior mandible in this study.
  • [MeSH-major] Jaw Neoplasms / epidemiology. Odontogenic Tumors / epidemiology

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  • (PMID = 20881331.001).
  • [ISSN] 1880-4926
  • [Journal-full-title] Journal of oral science
  • [ISO-abbreviation] J Oral Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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66. Arsene D, Georgescu A, Dănăilă L, Ardeleanu C: Giant intracranial endolymphatic sac tumor (ELST). Case presentation and histogenetic considerations. Rom J Morphol Embryol; 2008;49(1):85-90
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  • [Title] Giant intracranial endolymphatic sac tumor (ELST). Case presentation and histogenetic considerations.
  • We present a giant tumor of the skull base compressing the brain in a 40-years-old man.
  • The tumor was policystic at imaging.
  • Its histopathology, immunohistochemical profile and long evolution suggest an endolymphatic sac tumor (ELST), a rare case of neoplasia.
  • This could be from either the organ of Corti or some local cells that generate a resemblance with a systemic tumor, the so-called benign mesothelioma.
  • [MeSH-minor] Adult. Biomarkers, Tumor / metabolism. Humans. Male. Tumor Burden

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  • (PMID = 18273509.001).
  • [ISSN] 1220-0522
  • [Journal-full-title] Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
  • [ISO-abbreviation] Rom J Morphol Embryol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Romania
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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67. Alvarez Maestro M, Tur Gonzalez R, Alonso Dorrego JM, Jesus De la Peña Barthel J, Nistal Martin De Serrano M: [Adenomatoid tumors of the epididymis and testicle: report of 9 cases and bibliographic review]. Arch Esp Urol; 2009 Mar;62(2):137-41
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  • [Title] [Adenomatoid tumors of the epididymis and testicle: report of 9 cases and bibliographic review].
  • [Transliterated title] Tumor adenomatoide de epidídimo intratesticular: A proposito de nueve casos y revisión de la literatura.
  • BACKGROUND: To report the cases of adenomatoid tumors seen at Hospital Universitario La Paz in the last 15 years.
  • METHODS: A clinical, pathological, and surgical study was conducted of males with testicular or paratesticular tumors with a histological report of adenomatoid tumor.
  • RESULTS: Among the nine cases studied, seven had paratesticular and two intratesticular adenomatoid tumors.
  • Treatment of choice was mass removal for epididymal tumors and orchidectomy for intratesticular tumors.
  • CONCLUSIONS: Adenomatoid tumors are uncommon benign neoplasms of a possible mesothelial origin.
  • Because of their benign nature, the treatment of choice is local excision (conservative surgery), but orchidectomy was performed in two cases due to tumor location.
  • [MeSH-major] Adenomatoid Tumor. Epididymis. Genital Neoplasms, Male. Testicular Neoplasms

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  • (PMID = 19448282.001).
  • [ISSN] 0004-0614
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 10
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68. Fan SQ, Jiang Y, Li D, Wei QY: Adenomatoid tumour of the left adrenal gland with concurrent left nephrolithiasis and left kidney cyst. Pathology; 2005 Oct;37(5):398-400
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  • [Title] Adenomatoid tumour of the left adrenal gland with concurrent left nephrolithiasis and left kidney cyst.
  • [MeSH-major] Adenomatoid Tumor / pathology. Adrenal Gland Neoplasms / pathology. Cysts / pathology. Kidney Calculi / pathology. Kidney Diseases / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Calcinosis / pathology. Humans. Immunohistochemistry. Male. Tomography, X-Ray Computed

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  • (PMID = 16194858.001).
  • [ISSN] 0031-3025
  • [Journal-full-title] Pathology
  • [ISO-abbreviation] Pathology
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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69. Santos JN, Lima FO, Romério P, Souza VF: Adenomatoid odontogenic tumor: an unusual case exhibiting cribriform aspect. Quintessence Int; 2008 Oct;39(9):777-81
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  • [Title] Adenomatoid odontogenic tumor: an unusual case exhibiting cribriform aspect.
  • The occurrence of areas exhibiting cribriform morphology in odontogenic tumors is not a very frequent finding.
  • This report describes the case of a 22-year-old man who presented with swelling in the left anterior maxilla.
  • Histopathologically, the lesion consisted of a cystic wall exhibiting an odontogenic epithelium lining composed of oval, angular, and elongated cells forming a cribriform pattern.
  • [MeSH-major] Maxillary Neoplasms / pathology. Odontogenic Tumors / pathology

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  • (PMID = 19093052.001).
  • [ISSN] 1936-7163
  • [Journal-full-title] Quintessence international (Berlin, Germany : 1985)
  • [ISO-abbreviation] Quintessence Int
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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70. Friedrich RE, Scheuer HA, Zustin J: Adenomatoid odontogenic tumor (AOT) of maxillary sinus: case report with respect to immunohistochemical findings. In Vivo; 2009 Jan-Feb;23(1):111-6
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  • [Title] Adenomatoid odontogenic tumor (AOT) of maxillary sinus: case report with respect to immunohistochemical findings.
  • This report describes the surgical therapy, clinical course and morphological characteristics of an adenomatoid odontogenic tumor that developed in the maxilla of a 16-year-old patient.
  • The cystic tumor filled the maxillary sinus and was removed with the retained tooth.
  • The tumor showed immunoreactivity for certain types of cytokeratins, vimentin and p63, and was focally immunoreactive for alpha smooth muscle actin and epithelial membrane antigen.
  • [MeSH-major] Maxillary Sinus / pathology. Maxillary Sinus Neoplasms / pathology. Odontogenic Tumors / pathology
  • [MeSH-minor] Adolescent. Biomarkers, Tumor / metabolism. Humans. Male. Treatment Outcome

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  • (PMID = 19368134.001).
  • [ISSN] 0258-851X
  • [Journal-full-title] In vivo (Athens, Greece)
  • [ISO-abbreviation] In Vivo
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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71. Schwartz A, Peycru T, Tardat E, Dufau JP, Jarry J, Durand-Dastes F: [Peritoneal cystic mesothelioma: benign or malignant?]. J Chir (Paris); 2008 Sep-Oct;145(5):511-2
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  • [Title] [Peritoneal cystic mesothelioma: benign or malignant?].
  • [MeSH-major] Mesothelioma, Cystic / pathology. Peritoneal Neoplasms / pathology

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  • (PMID = 19106878.001).
  • [ISSN] 0021-7697
  • [Journal-full-title] Journal de chirurgie
  • [ISO-abbreviation] J Chir (Paris)
  • [Language] fre
  • [Publication-type] Case Reports; Letter
  • [Publication-country] France
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72. Minhas K, Barakzai A, Qureshi A: Fibromatous periorchitis. J Pak Med Assoc; 2009 Jan;59(1):47-9
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  • Although fibrous pseudotumours of this region are uncommon, they are reported to be the second most common benign paratesticular lesion after adenomatoid tumours.

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  • (PMID = 19213380.001).
  • [ISSN] 0030-9982
  • [Journal-full-title] JPMA. The Journal of the Pakistan Medical Association
  • [ISO-abbreviation] J Pak Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
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73. Sollami S, Ben Salah I, Chelif M, Hafsia G, Ben Rhouma S, Nouira Y, Horchani A: [Intrascrotal adenomatoid tumors]. Tunis Med; 2008 Jun;86(6):626
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  • [Title] [Intrascrotal adenomatoid tumors].
  • [MeSH-major] Adenomatoid Tumor / pathology. Epididymis. Genital Neoplasms, Male / pathology. Scrotum

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  • (PMID = 19216473.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Tunisia
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74. Liu YQ, Zhang HX, Wang GL, Ma LL, Huang Y: A giant cystic adenomatoid tumor of the adrenal gland: a case report. Chin Med J (Engl); 2010 Feb 5;123(3):372-4
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  • [Title] A giant cystic adenomatoid tumor of the adrenal gland: a case report.
  • [MeSH-major] Adenomatoid Tumor / diagnosis. Adrenal Gland Neoplasms / diagnosis

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  • (PMID = 20193264.001).
  • [ISSN] 0366-6999
  • [Journal-full-title] Chinese medical journal
  • [ISO-abbreviation] Chin. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
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75. McGuff HS, Alderson GL, Jones AC, Edgin WA: Oral and maxillofacial pathology case of the month. Adenomatoid odontogenic tumor. Tex Dent J; 2008 Dec;125(12):1192-5
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  • [Title] Oral and maxillofacial pathology case of the month. Adenomatoid odontogenic tumor.
  • [MeSH-major] Mandibular Neoplasms / diagnosis. Odontogenic Tumors / diagnosis

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  • (PMID = 19227115.001).
  • [ISSN] 0040-4284
  • [Journal-full-title] Texas dental journal
  • [ISO-abbreviation] Tex Dent J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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76. Roffman E, Baredes S, Mirani N: Respiratory epithelial adenomatoid hamartomas and chondroosseous respiratory epithelial hamartomas of the sinonasal tract: a case series and literature review. Am J Rhinol; 2006 Nov-Dec;20(6):586-90
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  • [Title] Respiratory epithelial adenomatoid hamartomas and chondroosseous respiratory epithelial hamartomas of the sinonasal tract: a case series and literature review.
  • BACKGROUND: Respiratory epithelial adenomatoid hamartomas (REAH) and chondroosseous respiratory epithelial (CORE) hamartomas are rare sinonasal/nasopharyngeal lesions first characterized in 1995.
  • Although REAH and CORE hamartomas are benign, nonneoplastic lesions, awareness and recognition of these lesions are important because they can be confused grossly and microscopically with more threatening sinonasal tumors.
  • METHODS: This report presents two cases of REAH and one case of a CORE hamartoma.

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  • (PMID = 17181098.001).
  • [ISSN] 1050-6586
  • [Journal-full-title] American journal of rhinology
  • [ISO-abbreviation] Am J Rhinol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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77. Scherpereel A, Grigoriu B, Conti M, Gey T, Grégoire M, Copin MC, Devos P, Chahine B, Porte H, Lassalle P: Soluble mesothelin-related peptides in the diagnosis of malignant pleural mesothelioma. Am J Respir Crit Care Med; 2006 May 15;173(10):1155-60
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  • [Title] Soluble mesothelin-related peptides in the diagnosis of malignant pleural mesothelioma.
  • BACKGROUND: Diagnosis of malignant pleural mesothelioma is a challenging issue.
  • Potential markers in mesothelioma diagnosis include soluble mesothelin-related peptides (SMRPs) and osteopontin, but no subsequent validation has been published yet.
  • METHODS: We prospectively evaluated SMRPs in serum and pleural effusion from patients with mesothelioma (n = 74), pleural metastasis of carcinomas (n = 35), or benign pleural lesions associated with asbestos exposure (n = 28), recruited when first suspected for mesothelioma.
  • FINDINGS: Mean serum SMRP level was higher in patients with mesothelioma (2.05 +/- 2.57 nM/L [median +/- interquartile range]) than in patients with metastasis (1.02 +/- 1.79 nM/L) or benign lesions (0.55 +/- 0.59 nM/L).
  • The area under the receiver operating characteristic curve (AUC) for serum SMRP was 0.872 for differentiating mesothelioma and benign lesions, cut-off = 0.93 nM/L (sensitivity = 80%, specificity = 82.6%).
  • The AUC for serum SMRP differentiating metastasis and mesothelioma was 0.693, cut-off = 1.85 nM/L (sensitivity = 58.3%, specificity = 73.3%).
  • SMRP values in pleural fluid were higher than in serum in all groups (mesothelioma: 46.1 +/- 83.2 nM/L; benign lesions: 6.4 +/- 11.1 nM/L; metastasis: 6.36 +/- 21.73 nM/L).
  • The AUC for pleural SMRP-differentiating benign lesions and mesothelioma was 0.831, cut-off = 10.4 nM/L (sensitivity = 76.7%, specificity = 76.2%).
  • The AUC for pleural SMRP-differentiating metastasis and mesothelioma was 0.793.
  • INTERPRETATION: We show that SMRPs may be a promising marker for mesothelioma diagnosis when measured either in serum or pleural fluid.
  • The diagnostic value of SMRPs was similar in both types of samples, but pleural fluid SMRPs may better discriminate mesothelioma from pleural metastasis.
  • [MeSH-major] Asbestosis / pathology. Membrane Glycoproteins / metabolism. Mesothelioma / pathology. Pleural Effusion, Malignant / diagnosis. Pleural Neoplasms / pathology. Sialoglycoproteins / metabolism
  • [MeSH-minor] Aged. Analysis of Variance. Area Under Curve. Biomarkers, Tumor / analysis. Diagnosis, Differential. Disease Progression. Female. GPI-Linked Proteins. Humans. Male. Middle Aged. Neoplasm Staging. Osteopontin. Prognosis. Prospective Studies. Sensitivity and Specificity. Solubility. Survival Analysis

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  • (PMID = 16456138.001).
  • [ISSN] 1073-449X
  • [Journal-full-title] American journal of respiratory and critical care medicine
  • [ISO-abbreviation] Am. J. Respir. Crit. Care Med.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / GPI-Linked Proteins; 0 / Membrane Glycoproteins; 0 / SPP1 protein, human; 0 / Sialoglycoproteins; 0 / mesothelin; 106441-73-0 / Osteopontin
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78. Yildirim H, Metintas M, Entok E, Ak G, Ak I, Dundar E, Erginel S: Clinical value of fluorodeoxyglucose-positron emission tomography/computed tomography in differentiation of malignant mesothelioma from asbestos-related benign pleural disease: an observational pilot study. J Thorac Oncol; 2009 Dec;4(12):1480-4
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  • [Title] Clinical value of fluorodeoxyglucose-positron emission tomography/computed tomography in differentiation of malignant mesothelioma from asbestos-related benign pleural disease: an observational pilot study.
  • In this pilot study, we investigate the role of 18F-FDG positron emission tomography/computed tomography (PET/CT) for differentiating asbestos-related benign pleural disease from malignant mesothelioma.
  • MATERIALS AND METHODS: The study population comprised 31 consecutive patients (17 malignant mesotheliomas, nine benign asbestos pleurisies, and five diffuse pleural fibrosis) with a mean age of 61 years between January 2006 and December 2008.
  • ROCs analyses for standardized uptake value (SUV) adjusted to body weight were calculated between benign and malignant pleural diseases.
  • RESULTS: 18F-FDG PET/CT imaging correctly detected the presence of malignancies in 15 of 17 patients with malignant mesothelioma for sensitivity, specificity, and overall accuracy of 88.2%, 92.9%, and 90.3%, respectively.
  • 18F-FDG PET/CT imaging correctly identified 13 of 14 cases of benign pleural disease.
  • The mean SUV values were 6.5 +/- 3.4 for malignant mesothelioma cases and 0.8 +/- 0.6 for benign pleural diseases (p < 0.001).
  • When we compared the two groups of pleural disease, a cut-off value of 2.2 for SUV gave the best accuracy with 94.1%, 100%, 100%, and 93.3% for sensitivity, specificity, positive predictive value, and negative predictive value, respectively.
  • CONCLUSION: Preliminary results of this trial provide evidence that 18F-FDG PET/CT imaging is a highly accurate and reliable noninvasive test to decide for further investigation of differentiating malignant mesothelioma from benign pleural disease.
  • [MeSH-major] Asbestos / adverse effects. Fluorodeoxyglucose F18. Mesothelioma / radionuclide imaging. Pleural Diseases / radionuclide imaging. Pleural Neoplasms / radionuclide imaging. Positron-Emission Tomography / methods. Radiopharmaceuticals

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  • (PMID = 19875971.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Carcinogens; 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18; 1332-21-4 / Asbestos
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79. Hoffmann M, Yedibela S, Dimmler A, Hohenberger W, Meyer T: Adenomatoid tumor of the adrenal gland mimicking an echinococcus cyst of the liver--a case report. Int J Surg; 2008 Dec;6(6):485-7
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  • [Title] Adenomatoid tumor of the adrenal gland mimicking an echinococcus cyst of the liver--a case report.
  • [MeSH-major] Adenomatoid Tumor / pathology. Adrenal Gland Neoplasms / pathology

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  • (PMID = 19059154.001).
  • [ISSN] 1743-9159
  • [Journal-full-title] International journal of surgery (London, England)
  • [ISO-abbreviation] Int J Surg
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
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80. Llarena Ibarguren R, Rodríguez JG, Olano Grasa I, Azurmendi Arín I, Cantón Aller E, Pertusa Peña C: [Adenomatoid tumor of the epididymis. Report of five cases]. Arch Esp Urol; 2008 Sep;61(7):831-4
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  • [Title] [Adenomatoid tumor of the epididymis. Report of five cases].
  • [Transliterated title] Tumor adenomatoide epididimario. Aportación de 5 casos.
  • OBJECTIVE: Adenomatoid tumor of the epididymis is unfrequent, benign, with no malignant outcomes described.
  • METHODS: We report five cases, with patient's ages varying from 31 to 76 years, and tumor sizes from 6 to 30 mm.
  • Pathology confirmed the benign adenomatoid character in all cases.
  • CONCLUSIONS: Despite the clinical, ultrasound and physical examination findings suggest the localization in the epididymis and its benign character, surgical exploration is mandatory with surgical excision of the paratesticular mass.
  • [MeSH-major] Adenomatoid Tumor. Epididymis. Genital Neoplasms, Male

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  • (PMID = 18972922.001).
  • [ISSN] 0004-0614
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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81. Leon JE, Mata GM, Fregnani ER, Carlos-Bregni R, de Almeida OP, Mosqueda-Taylor A, Vargas PA: Clinicopathological and immunohistochemical study of 39 cases of Adenomatoid Odontogenic Tumour: a multicentric study. Oral Oncol; 2005 Sep;41(8):835-42
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  • [Title] Clinicopathological and immunohistochemical study of 39 cases of Adenomatoid Odontogenic Tumour: a multicentric study.
  • Adenomatoid Odontogenic Tumour (AOT) is a relatively uncommon odontogenic lesion and few studies describing its cytokeratin profile have been reported in the English-language literature.
  • Calcifying epithelial odontogenic tumour (CEOT)-like areas were found in 36 out of 39 cases, and 10 cases showed positivity for Congo red in polarized light.
  • Vimentin was also expressed in 27 cases and this profile may indicate the existence of a variable phenotype in certain areas of the tumour.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Keratins / metabolism. Mandibular Neoplasms / pathology. Maxillary Neoplasms / pathology. Odontogenic Tumors / pathology

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  • (PMID = 15979930.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 68238-35-7 / Keratins
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82. Motamedi MH, Shafeie HA, Azizi T: Salvage of an impacted canine associated with an adenomatoid odontogenic tumour: a case report. Br Dent J; 2005 Jul 23;199(2):89-90
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  • [Title] Salvage of an impacted canine associated with an adenomatoid odontogenic tumour: a case report.
  • The adenomatoid odontogenic tumour (AOT) has been known by a number of descriptive names (adenoameloblastoma, ameloblastic adenomatoid tumour, glandular ameloblastoma, and adenomatoid ameloblastoma) since it was first reported and later recognised as a distinct odontogenic lesion unrelated to ameloblastoma.
  • Although it was considered to be a variant of ameloblastoma at one time leading surgeons to perform unduly aggressive surgery, the treatment outcome experience has borne out the benign, nonaggressive nature of this lesion.
  • The AOT is now considered to be a hamartoma with completely benign behaviour.
  • Thus, it appears needless to extract involved anterior teeth associated with the tumour, especially in children.
  • We have not found such a procedure to have been done for this tumour in the literature.
  • [MeSH-major] Cuspid / pathology. Mandibular Neoplasms / complications. Odontogenic Tumors / complications. Tooth Movement / methods. Tooth, Impacted / etiology

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  • (PMID = 16041334.001).
  • [ISSN] 0007-0610
  • [Journal-full-title] British dental journal
  • [ISO-abbreviation] Br Dent J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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83. Rizkalla HF, Higgins M, Kelehan P, O'Herlihy C: Pathological findings associated with the presence of a mirena intrauterine system at hysterectomy. Int J Gynecol Pathol; 2008 Jan;27(1):74-8
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  • [Title] Pathological findings associated with the presence of a mirena intrauterine system at hysterectomy.
  • Thirty hysterectomy specimens contained benign leiomyomata with associated reduced reactivity in the uterine cavity and incomplete suppression of the endometrium.
  • In addition to leiomyomas, 1 specimen had an atypical polypoid adenomyoma and 1 had a benign adenomatoid tumor.


84. Gomes CC, Oliveira Cda S, Castro WH, de Lacerda JC, Gomez RS: Clonal nature of odontogenic tumours. J Oral Pathol Med; 2009 Apr;38(4):397-400
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clonal nature of odontogenic tumours.
  • BACKGROUND: Although clonal origin is an essential step in the comprehension of neoplasias, there have been no studies to examine whether odontogenic tumours are derived from a single somatic progenitor cell.
  • The purpose of this study was to investigate the clonal origin of odontogenic tumours.
  • METHODS: Fresh samples of seven ameloblastomas, two odontogenic mixomas, two adenomatoid odontogenic tumour, one calcifying odontogenic cyst, one calcifying epithelial odontogenic tumour (CEOT) and six odontogenic keratocyst (OKC) of female patients were included in this study.
  • CONCLUSIONS: Our results suggest that most odontogenic tumours are monoclonal.
  • [MeSH-major] Odontogenic Tumors / genetics. Odontogenic Tumors / pathology
  • [MeSH-minor] Clone Cells. DNA Methylation. DNA, Neoplasm / analysis. Epigenesis, Genetic. Female. Humans

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  • (PMID = 19298504.001).
  • [ISSN] 1600-0714
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / DNA, Neoplasm
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85. Chen S, Wang S, Gao J, Zhang S: [Pleuropulmonary blastoma: a clinicopathological analysis]. Zhongguo Fei Ai Za Zhi; 2010 May;13(5):550-3
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  • BACKGROUND AND OBJECTIVE: Pleuropulmonary blastoma (PPB) is a rare malignant tumor with unique clinicopathological features.
  • Histologically, these tumors included 1 case of type I PPB which showed pure cystic architecture; 2 cases were type II PPB which showed cystic and solid masses accompanied with rhabdomyoblastic differentiation and nodules of cartilage; the other 2 cases were type III PPB and characterized by absolute solid masses with anaplastic undifferentiated sarcomatous components.
  • Immunohistochemical studies showed that tumor cells were positive for Vimentin and some for Desmin and Myogenin, the nodules of cartilage were positive for S-100.
  • The tumor cells were negative for PCK, EMA and CD99.
  • This kind of tumor should be distinguished from some benign and malignant diseases such as congenital cystic adenomatoid malformation (CCAM) and embryonal rhabdomyosarcoma.


86. Ide F: Inter-radicular adenomatoid odontogenic tumor of the anterior mandible. J Oral Maxillofac Surg; 2010 Feb;68(2):490-1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Inter-radicular adenomatoid odontogenic tumor of the anterior mandible.
  • [MeSH-major] Mandibular Neoplasms / pathology. Odontogenic Tumors / pathology

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  • [CommentOn] J Oral Maxillofac Surg. 2009 Sep;67(9):1961-5 [19686935.001]
  • (PMID = 20116733.001).
  • [ISSN] 1531-5053
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Comment; Letter
  • [Publication-country] United States
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87. Wojewoda CM, Wasman JK, MacLennan GT: Adenomatoid tumor of the adrenal gland. J Urol; 2008 Sep;180(3):1123
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  • [Title] Adenomatoid tumor of the adrenal gland.
  • [MeSH-major] Adenomatoid Tumor / pathology. Adrenal Gland Neoplasms / pathology

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  • (PMID = 18639286.001).
  • [ISSN] 1527-3792
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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88. Ide F, Mishima K, Saito I, Kusama K: Diagnostically challenging epithelial odontogenic tumors: a selective review of 7 jawbone lesions. Head Neck Pathol; 2009 Mar;3(1):18-26
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diagnostically challenging epithelial odontogenic tumors: a selective review of 7 jawbone lesions.
  • Considerable variation in the clinicopathologic presentation of epithelial odontogenic tumors can sometimes be confusing and increase the chance of misdiagnosis.
  • The other globulomaxillary lesion was managed under the erroneous diagnosis of adenomatoid odontogenic tumor and recurred 4 times over an 11-year period.
  • This tumor was found in retrospect to be consistent with an adenoid ameloblastoma with dentinoid.
  • The diagnosis of cystic squamous odontogenic tumor (SOT) occurring as a radicular lesion of an impacted lower third molar was one of exclusion.
  • Of two unsuspected keratocystic odontogenic tumors, one depicted deceptive features of pericoronitis, while the other case has long been in our files with the diagnosis of globulomaxillary SOT.
  • Two cases of primary intraosseous squamous cell carcinoma appeared benign clinically and exhibited unexpected findings; an impacted third molar began to erupt in association with the growth of carcinoma and another periradicular carcinoma showed dentinoid formation.
  • [MeSH-major] Jaw Neoplasms / diagnosis. Odontogenic Tumors / diagnosis

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  • (PMID = 20596984.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 41
  • [Other-IDs] NLM/ PMC2807539
  • [Keywords] NOTNLM ; Clinicopathologic correlation / Diagnostic pitfall / Epithelial odontogenic tumor / Jawbone
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89. Baughman R: Diagnostic quiz. Case no. 1: adenomatoid odontogenic tumor. Todays FDA; 2006 Aug;18(8):22, 25
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diagnostic quiz. Case no. 1: adenomatoid odontogenic tumor.
  • [MeSH-major] Maxillary Neoplasms / diagnosis. Odontogenic Tumors / diagnosis

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  • (PMID = 19226725.001).
  • [ISSN] 1048-5317
  • [Journal-full-title] Today's FDA : official monthly journal of the Florida Dental Association
  • [ISO-abbreviation] Todays FDA
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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90. Philipsen HP, Reichart PA, Siar CH, Ng KH, Lau SH, Zhang X, Dhanuthai K, Swasdison S, Jainkittivong A, Meer S, Jivan V, Altini M, Hazarey V, Ogawa I, Takata T, Taylor AA, Godoy H, Delgado WA, Carlos-Bregni R, Macias JF, Matsuzaka K, Sato D, Vargas PA, Adebayo ET: An updated clinical and epidemiological profile of the adenomatoid odontogenic tumour: a collaborative retrospective study. J Oral Pathol Med; 2007 Aug;36(7):383-93
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  • [Title] An updated clinical and epidemiological profile of the adenomatoid odontogenic tumour: a collaborative retrospective study.
  • BACKGROUND: Adenomatoid odontogenic tumour (AOT) is a benign odontogenic jaw lesion.
  • RESULTS: 550 new cases were retrieved, and of a total of 1082 cases analysed, 87.2% were found in the second and third decades.
  • The M:F ratio was 1:1.9.
  • CONCLUSIONS: This updated review based on the largest number of AOT cases ever presented, confirms the distinctive, although not pathognomonic clinicopathological profile of the AOT, its worldwide occurrence, and its consistently benign behaviour.
  • [MeSH-major] Jaw Neoplasms / epidemiology. Odontogenic Tumors / epidemiology

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  • (PMID = 17617830.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] Denmark
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91. Carlos-Bregni R, Vargas PA, Santos Silva AR, Chaves-Netto HD, de Moraes M, Lopes MA: Adenomatoid odontogenic hamartoma: concerns about correct nomenclature and 2 additional case reports. J Oral Maxillofac Surg; 2009 Aug;67(8):1779-80; author reply 1780
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  • [Title] Adenomatoid odontogenic hamartoma: concerns about correct nomenclature and 2 additional case reports.
  • [MeSH-major] Hamartoma / pathology. Mandibular Diseases / pathology. Mandibular Neoplasms / pathology. Odontogenic Tumors / pathology. Terminology as Topic

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  • [CommentOn] J Oral Maxillofac Surg. 2008 Jul;66(7):1489-91 [18571036.001]
  • (PMID = 19615603.001).
  • [ISSN] 1531-5053
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Comment; Letter
  • [Publication-country] United States
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92. Kalidindi M, Odejinmi F: Laparoscopic excision of uterine adenomatoid tumour: two cases and literature review. Arch Gynecol Obstet; 2010 Feb;281(2):311-5
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  • [Title] Laparoscopic excision of uterine adenomatoid tumour: two cases and literature review.
  • INTRODUCTION: Adenomatoid tumours are rare, benign neoplasms of the genital tract, occurring most commonly during the reproductive years.
  • These tumours can be associated with fibroids and tend to mimic them clinically and radiologically, making pre-operative diagnosis very difficult.
  • We report two cases of uterine adenomatoid tumours that were excised laparoscopically.
  • Intraoperatively, there was no clear line of demarcation between the uterus and the tumours and laparoscopic manipulation of the tumours was difficult due to their friable nature.
  • CONCLUSION: Adenomatoid tumours should always be included in the differential diagnosis along with adenomyosis and post-GnRH analogue treatment changes, when difficulty is encountered in identification of operative planes during a routine laparoscopic myomectomy.
  • Apart from explaining the operative difficulties, the identification of these tumours also helps in post-operative counselling of these patients as these tumours unlike fibroids do not recur.
  • [MeSH-major] Adenomatoid Tumor / pathology. Uterine Neoplasms / pathology

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  • (PMID = 19434414.001).
  • [ISSN] 1432-0711
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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93. Mitsui Y, Ueda Y, Suzuki T, Shincho M, Higuchi Y, Qiu J, Maruyama T, Kondoh N, Nojima M, Yamamoto S, Hirota S, Shima H: [A case of adenomatoid tumor of the testis treated by testis-sparing surgery: a case report]. Hinyokika Kiyo; 2008 May;54(5):383-6
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  • [Title] [A case of adenomatoid tumor of the testis treated by testis-sparing surgery: a case report].
  • A 44-year-old man was referred to our hospital with a chief complaint of a painless left intrascrotal mass, palpable at the lower portion of the left testis.
  • Serum levels of tumor markers, human choriogenic gonadotropin (hCG), hCG-beta, and alpha fetoprotein were within the normal limits.
  • Ultrasonography revealed a hyperechoic mass 13 mm in diameter, which was demonstrated as a hypovascular tumor by Gadrinium-enhanced magnetic resonance imaging.
  • Since the tumor was diagnosed as a benign tumor by frozen section examination intraoperatively, testis-sparing surgery was performed.
  • Histological examination revealed adenomatoid tumor originating from the tunica alubuginea of testis.
  • Adenomatoid tumor of the testis is a rare benign tumor, and the present case is the 36th one in the Japanese literature.
  • [MeSH-major] Adenomatoid Tumor / surgery

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  • (PMID = 18546867.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 16
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94. Gadewar DR, Srikant N: Adenomatoid odontogenic tumour: tumour or a cyst, a histopathological support for the controversy. Int J Pediatr Otorhinolaryngol; 2010 Apr;74(4):333-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumour: tumour or a cyst, a histopathological support for the controversy.
  • Adenomatoid odontogenic tumour (AOT) is a well-established odontogenic tumour with various clinicopathological variants.
  • [MeSH-major] Adenomatoid Tumor / pathology. Maxillary Neoplasms / pathology. Odontogenic Tumors / pathology

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  • [CommentIn] Int J Pediatr Otorhinolaryngol. 2010 Jul;74(7):836-7; author reply 837 [20413165.001]
  • (PMID = 20079941.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Ireland
  • [Number-of-references] 34
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95. Oepkes D, Devlieger R, Lopriore E, Klumper FJ: Successful ultrasound-guided laser treatment of fetal hydrops caused by pulmonary sequestration. Ultrasound Obstet Gynecol; 2007 Apr;29(4):457-9
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  • The most common of these lesions are microcystic congenital cystic adenomatoid malformations and pulmonary sequestrations (PS).
  • The blood flow to the lung tumor was successfully arrested and hydrops reversed.
  • It is therefore important to utilize color Doppler ultrasound imaging for identification of a systemic feeding blood vessel in solid fetal lung tumors.

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  • [Copyright] Copyright (c) 2007 ISUOG.
  • (PMID = 17352451.001).
  • [ISSN] 0960-7692
  • [Journal-full-title] Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology
  • [ISO-abbreviation] Ultrasound Obstet Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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96. Modolo F, Biz MT, Martins MT, Machado de Sousa SO, de Araújo NS: Expression of extracellular matrix proteins in adenomatoid odontogenic tumor. J Oral Pathol Med; 2010 Mar;39(3):230-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of extracellular matrix proteins in adenomatoid odontogenic tumor.
  • Altered expression of extracellular matrix (ECM) components has been reported in several pathologies; however, few ECM proteins have been evaluated in adenomatoid odontogenic tumor (AOT).
  • Only the osteonectin was expressed in the epithelial cells.
  • In conclusion, the low expression of the components studied in neoplastic epithelial cells suggests that the epithelial cells act probably as stimulators of the expression by the stroma, which in turn can act as agonist or antagonist of the tumor growth.
  • [MeSH-major] Extracellular Matrix Proteins / analysis. Odontogenic Tumors / pathology
  • [MeSH-minor] Biglycan. Calcinosis / pathology. Connective Tissue / pathology. Cytoplasm / ultrastructure. Decorin. Epithelial Cells / pathology. Gene Expression Regulation, Neoplastic / genetics. Humans. Integrin-Binding Sialoprotein. Osteocalcin / analysis. Osteonectin / analysis. Osteopontin / analysis. Proteoglycans / analysis. Sialoglycoproteins / analysis

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  • (PMID = 20070486.001).
  • [ISSN] 1600-0714
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / BGN protein, human; 0 / Biglycan; 0 / DCN protein, human; 0 / Decorin; 0 / Extracellular Matrix Proteins; 0 / IBSP protein, human; 0 / Integrin-Binding Sialoprotein; 0 / Osteonectin; 0 / Proteoglycans; 0 / Sialoglycoproteins; 104982-03-8 / Osteocalcin; 106441-73-0 / Osteopontin
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97. Weissferdt A, Kalhor N, Suster S, Moran CA: Adenomatoid spindle cell thymomas: a clinicopathological and immunohistochemical study of 20 cases. Am J Surg Pathol; 2010 Oct;34(10):1544-9
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  • [Title] Adenomatoid spindle cell thymomas: a clinicopathological and immunohistochemical study of 20 cases.
  • Twenty cases of adenomatoid spindle cell thymomas are presented.
  • Grossly, the tumors were described as well-defined solid tumor masses surrounded by membranous tissue, which at cut surface show a light tan homogenous surface.
  • Histologically, all tumors showed similar histological features and were characterized by the presence of a spindle cellular proliferation with an "adenomatoid-like" appearance, which at higher magnification showed the presence of cells with a signet-ring cell-like appearance.
  • Seven tumors showed transcapsular invasion, whereas 13 cases were encapsulate.
  • Immunohistochemical studies showed positive staining for broad-spectrum keratin and keratin 7 with only scattered cells positive for calretinin and epithelial membrane antigen.
  • The cases herein described highlight the importance of recognizing this unusual pattern of spindle cell thymomas to avoid misdiagnosis with other tumors, namely, when dealing with small mediastinoscopic biopsies.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / metabolism. Child. Female. Humans. Keratins / metabolism. Male. Middle Aged. Young Adult

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  • (PMID = 20852406.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 68238-35-7 / Keratins
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98. Zhong Y, Wang L, Chen XM: [Expression of p-p38MARK, uPA and Ki-67 in epithelial odontogenic tumour]. Zhonghua Kou Qiang Yi Xue Za Zhi; 2010 Sep;45(9):535-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Expression of p-p38MARK, uPA and Ki-67 in epithelial odontogenic tumour].
  • METHODS: the specimens of ameloblastoma (AB), keratocystic odontogenic tumour (KCOT), calcifying epithelial odontogenic tumor (CEOT), adenomatoid odontogenic tumour (AOT), calcifying cystic odontogenic tumour (CCOT) and 5 tooth germs were examined immunohistochemically for the expression of p-p38MAPK, uPA and Ki-67.
  • RESULTS: p-p38MAPK was detected both in the cytoplasm and the nucleus of the epithelial odontogenic tumour cells and uPA in the cytoplasm of the epithelial odontogenic tumour cells.
  • Furthermore, there was a statistically significant difference in the expression of p-p38MAPK, uPA and Ki-67 between epithelial odontogenic tumor group and tooth germ group (P < 0.05).
  • CONCLUSIONS: the p38MAPK-signaling pathway could promote tumour growth and invasion in epithelial odontogenic tumour by up-regulating uPA protein expression and may play a role in oncogenesis, invasion and proliferation of epithelial odontogenic tumour.
  • [MeSH-major] Cell Transformation, Neoplastic. Odontogenic Cyst, Calcifying / metabolism. Odontogenic Tumors / metabolism. Signal Transduction. Skin Neoplasms / metabolism. Urokinase-Type Plasminogen Activator / biosynthesis. p38 Mitogen-Activated Protein Kinases / biosynthesis
  • [MeSH-minor] Ameloblastoma. Epithelial Cells. Humans. Phosphorylation. Tooth Germ

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  • (PMID = 21122446.001).
  • [ISSN] 1002-0098
  • [Journal-full-title] Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
  • [ISO-abbreviation] Zhonghua Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] EC 2.7.11.24 / p38 Mitogen-Activated Protein Kinases; EC 3.4.21.73 / Urokinase-Type Plasminogen Activator; Adenoameloblastoma; Calcifying Epithelial Odontogenic Tumor
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99. Mihai R, Parker AJ, Roskell D, Sadler GP: One in four patients with follicular thyroid cytology (THY3) has a thyroid carcinoma. Thyroid; 2009 Jan;19(1):33-7
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  • Cytological criteria for benign (THY2) and malignant (THY5) aspirates are well established and reliable.
  • When cytology suggests a follicular neoplasm (THY3), only formal histological assessment can differentiate between benign and malignant lesions.
  • The objective of this study was to determine the factors predictive of malignancy in thyroid nodules when cytological assessment is restricted to euthyroid patients living in an area without endemic goiter who undergo routine diagnostic lobectomy once the FNA raises the suspicion of a follicular neoplasm.
  • Benign tumors were found in 144 patients with follicular adenomas (n = 76), Hurthle cell adenomas (n = 33), multinodular goiter (n = 13), adenomatoid nodules (n = 15), colloid nodules (n = 4), and thyroiditis (n = 3).
  • CONCLUSION: One in four patients with cytological features of a follicular neoplasm has a thyroid carcinoma.

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  • (PMID = 18976164.001).
  • [ISSN] 1557-9077
  • [Journal-full-title] Thyroid : official journal of the American Thyroid Association
  • [ISO-abbreviation] Thyroid
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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100. Cao D, Li J, Guo CC, Allan RW, Humphrey PA: SALL4 is a novel diagnostic marker for testicular germ cell tumors. Am J Surg Pathol; 2009 Jul;33(7):1065-77
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  • [Title] SALL4 is a novel diagnostic marker for testicular germ cell tumors.
  • The diagnosis of testicular germ cell tumors (GCTs) sometimes can be challenging without ancillary markers.
  • Here we performed an immunohistochemical study of a novel stem cell marker SALL4 in a large series of 110 primary testicular GCTs (65 pure and 45 mixed) containing the following types of tumors and/or tumor components: 50 intratubular germ cell neoplasias (ITGCNs), 62 classic seminomas, 2 spermatocytic seminomas, 39 embryonal carcinomas (EC), 5 pediatric and 26 postpubertal yolk sac tumors (YST), 7 pediatric and 25 postpubertal teratomas, and 5 choriocarcinomas.
  • To test SALL4 specificity, 23 testicular non-GCTs (10 Leydig cell tumors, 4 Sertoli cell tumors, 3 adenomatoid tumors, 3 paratesticular rhabdomyosarcomas, 2 diffuse large B-cell lymphomas, and 1 rete testis papillary cystadenoma) and 275 nontesticular tumors (158 metastatic carcinomas, 12 metastatic melanomas, 11 primary and 2 metastatic mesotheliomas, and 72 primary and 20 metastatic sarcomas) were also stained for SALL4.
  • All ITGCNs, classic seminomas, and ECs demonstrated strong SALL4 and OCT4 staining in more than 90% tumor cells.
  • All 31 YSTs (5 pediatric and 26 postpubertal) showed strong positive SALL4 staining in more than 90% tumor cells but had negative OCT4 staining.
  • Both spermatocytic seminomas showed positive SALL4 staining in 80% to 95% tumor cells in all 3 types of tumor cells with weak-to-moderate staining intensity.
  • Of 275 nontesticular tumors, only 10 carcinomas and 1 sarcoma showed focal (<25% tumor cells) weak SALL4 staining.
  • Although all 31 YSTs showed glypican-3 staining, 14 (45%) show staining in less than 30% tumor cells.
  • [MeSH-major] Biomarkers, Tumor / analysis. Neoplasms, Germ Cell and Embryonal / diagnosis. Testicular Neoplasms / diagnosis. Transcription Factors / biosynthesis

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  • (PMID = 19390421.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / SALL4 protein, human; 0 / Transcription Factors
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