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1. Sangoi AR, McKenney JK, Schwartz EJ, Rouse RV, Longacre TA: Adenomatoid tumors of the female and male genital tracts: a clinicopathological and immunohistochemical study of 44 cases. Mod Pathol; 2009 Sep;22(9):1228-35
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid tumors of the female and male genital tracts: a clinicopathological and immunohistochemical study of 44 cases.
  • Adenomatoid tumors of the female and male genital tracts are well characterized as mesothelial in origin, but a detailed histological and immunohistochemical analysis comparing both traditional and newer mesothelial markers across gender and site has not been formally conducted.
  • A variety of morphologic features previously described as characteristic of adenomatoid tumors were evaluated in 44 adenomatoid tumors from the male and female genital tracts.
  • All (n=44) the adenomatoid tumors from both the female and male genital tracts demonstrated a distinctive thread-like bridging strand pattern.
  • Lymphoid aggregates were seen in all 12 adenomatoid tumors of male patients, but in only 4 of 32 (13%) tumors in female patients (P<0.0001).
  • The remaining morphologic features were variably present with no clear sex predilection.
  • Pankeratin, calretinin, and D2-40 reactivity were identified in all female (n=32) and male (n=12) genital tract adenomatoid tumors.
  • Adenomatoid tumors expressed WT-1 in 11/12 (92%) male patients and in 31/32 (97%) female patients.
  • In male patients, reactivity for CK5/6 and caldesmon was found in 1/12 (8%) and 0/12 (0%) adenomatoid tumors (respectively), whereas reactivity in female patients was found in 5/32 (16%) and 1/32 (3%); respectively.
  • Female tumors differ from their male counterparts by the frequent absence of lymphoid aggregates and the presence of a circumscribed margin when occurring in the fallopian tube.
  • Of the putative mesothelial markers evaluated, calretinin, D2-40, and WT-1 show a similar immunoprofile and have a higher sensitivity than CK5/6 and caldesmon in genital tract adenomatoid tumors.
  • [MeSH-major] Adenomatoid Tumor / pathology. Biomarkers, Tumor / analysis. Genital Neoplasms, Female / pathology. Genital Neoplasms, Male / pathology

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  • (PMID = 19543245.001).
  • [ISSN] 1530-0285
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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2. Barry P, Chan KG, Hsu J, Quek ML: Adenomatoid tumor of the tunica albuginea. Int J Urol; 2005 May;12(5):516-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid tumor of the tunica albuginea.
  • Adenomatoid tumors are benign mesothelial tumors most commonly found in the paratesticular structures, especially the epididymis.
  • Herein, we report a case of adenomatoid tumor originating in the tunica albuginea and mimicking an intratesticular neoplasm.
  • We review the ultrasonographic presentation and literature regarding adenomatoid tumors originating in the tunica albuginea and testicular parenchyma.
  • [MeSH-major] Adenomatoid Tumor / pathology. Testicular Neoplasms / pathology

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  • (PMID = 15948758.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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3. Amin W, Parwani AV: Adenomatoid tumor of testis. Clin Med Pathol; 2009;2:17-22

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid tumor of testis.
  • Adenomatoid tumors are responsible for 30% of all paratesticular masses.
  • They are benign tumors comprising of cords and tubules of cuboidal to columnar cells with vacuolated cytoplasm and fibrous stroma.
  • They are considered to be of mesothelial origin supported by histochemical studies and genetic analysis of Wilms tumor 1 gene expression.
  • Diagnostic studies include serum tumor markers (negative alpha fetoprotein, beta HCG, LDH) ultrasonography (hypoechoic and homogenous appearance) and frozen section.

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  • (PMID = 21151545.001).
  • [ISSN] 1178-1181
  • [Journal-full-title] Clinical medicine. Pathology
  • [ISO-abbreviation] Clin Med Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] New Zealand
  • [Other-IDs] NLM/ PMC2990235
  • [Keywords] NOTNLM ; adenomatoid tumor / paratesticluar masses
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4. Di Pierro GB, Sciarra A, Innocenzi M, Cristini C: [Rare case of multiple adenomatoid tumors arising from tunica vaginalis of testis and epididymis]. Actas Urol Esp; 2010 Jun;34(6):560-1
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  • [Title] [Rare case of multiple adenomatoid tumors arising from tunica vaginalis of testis and epididymis].
  • [Transliterated title] Raro caso de tumores adenomatoides múltiples derivados de la túnica vaginal de testículo y epidídimo.
  • [MeSH-major] Adenomatoid Tumor / pathology. Epididymis. Genital Neoplasms, Male / pathology. Neoplasms, Multiple Primary / pathology. Testicular Neoplasms / pathology

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  • (PMID = 20510121.001).
  • [ISSN] 1699-7980
  • [Journal-full-title] Actas urologicas españolas
  • [ISO-abbreviation] Actas Urol Esp
  • [Language] spa
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Spain
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5. Yeh HC, Wu WJ, Lee YC, Chang TH, Huang CH, Li CC: Leiomyoma of the epididymis: a case report. Kaohsiung J Med Sci; 2006 Oct;22(10):519-23

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Tumors of the epididymis, both primary and secondary, and whether benign or malignant, are very rare.
  • Adenomatoid tumors and leiomyoma are the most frequently diagnosed benign tumors of the epididymis.
  • In a review of the American and European literature, leiomyoma was the second most common neoplasm of the epididymis, representing 6% of primary epididymal tumors.
  • The patient presented with a 4-year history of a painless mass in the left scrotum.
  • There were no bother some symptoms except gradual enlargement of the tumor.
  • A fresh frozen section showed a benign lesion, and conservative excision of the tumor was performed without any difficulty.

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  • (PMID = 17098685.001).
  • [ISSN] 1607-551X
  • [Journal-full-title] The Kaohsiung journal of medical sciences
  • [ISO-abbreviation] Kaohsiung J. Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
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6. Yeh CJ, Chuang WY, Chou HH, Jung SM, Hsueh S: Multiple extragenital adenomatoid tumors in the mesocolon and omentum. APMIS; 2008 Nov;116(11):1016-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multiple extragenital adenomatoid tumors in the mesocolon and omentum.
  • Adenomatoid tumors are benign mesothelial neoplasms most commonly found in the male and female genital tracts.
  • Extragenital adenomatoid tumors are rare, most of them being solitary tumors.
  • To our knowledge, only one case of multiple extragenital adenomatoid tumors, involving the liver and peritoneum, has been reported to date.
  • Here we report another case of multiple extragenital adenomatoid tumors involving the mesocolon and omentum.
  • The patient was transferred to our hospital without resection due to the intraoperative finding of multiple peritoneal tumors.
  • At our hospital, an 8.0x7.5x6.0 cm tumor at the mesocolon of the sigmoid colon and three omental nodules measuring up to 2.5x2.0x1.7 cm were resected.
  • Immunohistochemically, the tumor cells were positive for pan-cytokeratin AE1/AE3, vimentin, cytokeratin 5/6 and calretinin.
  • Despite their rarity, adenomatoid tumors should be included in the differential diagnosis of multiple intra-abdominal tumors.
  • [MeSH-major] Adenomatoid Tumor / pathology. Mesocolon / pathology. Neoplasms, Multiple Primary / pathology. Omentum / pathology. Peritoneal Neoplasms / pathology

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  • (PMID = 19133002.001).
  • [ISSN] 1600-0463
  • [Journal-full-title] APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
  • [ISO-abbreviation] APMIS
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / CALB2 protein, human; 0 / Calbindin 2; 0 / S100 Calcium Binding Protein G; 0 / Vimentin; 68238-35-7 / Keratins
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7. Kontos S, Fokitis I, Karakosta A, Koritsiadis G, Mitsios K, Koutsikos S, Koritsiadis S: Adenomatoid tumor of epididymidis: A case report. Cases J; 2008;1(1):206

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid tumor of epididymidis: A case report.
  • BACKGROUND: Adenomatoid tumors are regarded as distinctive benign mesothelial neoplasms of the paratesticular region, most commonly occuring at the tail of the epididymidis.Because of its rarity, the clinical and histopathological aspects are discussed.
  • CASE PRESENTATION: We present the case of a 41-year-old patient with an adenomatoid tumour located in the tail of the left epididymis that referred to our department with gradual enlarged intrascrotal mass.

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  • (PMID = 18831762.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2566564
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8. Alvarez Maestro M, Tur Gonzalez R, Alonso Dorrego JM, Jesus De la Peña Barthel J, Nistal Martin De Serrano M: [Adenomatoid tumors of the epididymis and testicle: report of 9 cases and bibliographic review]. Arch Esp Urol; 2009 Mar;62(2):137-41
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  • [Title] [Adenomatoid tumors of the epididymis and testicle: report of 9 cases and bibliographic review].
  • [Transliterated title] Tumor adenomatoide de epidídimo intratesticular: A proposito de nueve casos y revisión de la literatura.
  • BACKGROUND: To report the cases of adenomatoid tumors seen at Hospital Universitario La Paz in the last 15 years.
  • METHODS: A clinical, pathological, and surgical study was conducted of males with testicular or paratesticular tumors with a histological report of adenomatoid tumor.
  • RESULTS: Among the nine cases studied, seven had paratesticular and two intratesticular adenomatoid tumors.
  • Treatment of choice was mass removal for epididymal tumors and orchidectomy for intratesticular tumors.
  • CONCLUSIONS: Adenomatoid tumors are uncommon benign neoplasms of a possible mesothelial origin.
  • Because of their benign nature, the treatment of choice is local excision (conservative surgery), but orchidectomy was performed in two cases due to tumor location.
  • [MeSH-major] Adenomatoid Tumor. Epididymis. Genital Neoplasms, Male. Testicular Neoplasms

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  • (PMID = 19448282.001).
  • [ISSN] 0004-0614
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 10
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9. Garg K, Lee P, Ro JY, Qu Z, Troncoso P, Ayala AG: Adenomatoid tumor of the adrenal gland: a clinicopathologic study of 3 cases. Ann Diagn Pathol; 2005 Feb;9(1):11-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid tumor of the adrenal gland: a clinicopathologic study of 3 cases.
  • Adenomatoid tumors are relatively uncommon benign neoplasms of mesothelial origin, usually occurring in the male and female genital tracts.
  • Rare extragenital adenomatoid tumors have been identified in the adrenal glands, heart, mesentery, pleura, and lymph nodes.
  • In the adrenal gland, adenomatoid tumors may pose a diagnostic challenge.
  • Because of its glandular pattern, an adenomatoid tumor may be confused with an adenocarcinoma.
  • We present 3 cases of adrenal adenomatoid tumors, including one with a concurrent large hemorrhagic vascular adrenal cyst.
  • The adenomatoid tumors were unilateral, appeared solid and white, and varied from 1.7 to 4.2 cm in diameter.
  • One patient presented with abdominal pain due to the presence of a concurrent large adrenal cyst.
  • The tumor was an incidental radiological finding in another case and was discovered during the course of a workup for hypertension in the third case.
  • The light microscopic appearances were consistent with those of typical adenomatoid tumors.
  • Immunohistochemical stains for calretinin and cytokeratin 5/6 were positive, confirming the tumors' mesothelial origin.
  • In our experience, the key to the diagnosis of this rare benign tumor is to consider adenomatoid tumor in the differential diagnosis of any glandular tumor occurring in the adrenal gland.
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adult. Biomarkers, Tumor / metabolism. Calbindin 2. Carcinoma, Signet Ring Cell / diagnosis. Carcinoma, Signet Ring Cell / secondary. Cysts / complications. Cysts / metabolism. Cysts / pathology. Diagnosis, Differential. Humans. Immunohistochemistry. Keratins / metabolism. Male. Middle Aged. S100 Calcium Binding Protein G / metabolism. Treatment Outcome

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  • (PMID = 15692945.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CALB2 protein, human; 0 / Calbindin 2; 0 / S100 Calcium Binding Protein G; 68238-35-7 / Keratins
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10. Leaha C, Opris I, Macé P, Resch B, Sabourin JC: [Cystic adenomatoid tumor of the uterus]. Ann Pathol; 2009 Apr;29(2):134-7
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  • [Title] [Cystic adenomatoid tumor of the uterus].
  • [Transliterated title] Tumeur adénomatoïde kystique utérine.
  • Adenomatoid tumors are benign neoplasms of mesothelial origin, which involve the feminine and masculine genital tracts.
  • Our study presents an adenomatoid tumour, of cystic shape, which enables discussion of the histogenesis of this tumour and enlightenment of differential diagnoses which can at times result in an incorrect malignant diagnosis.
  • [MeSH-major] Adenomatoid Tumor / pathology. Uterine Neoplasms / pathology

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  • (PMID = 19364588.001).
  • [ISSN] 0242-6498
  • [Journal-full-title] Annales de pathologie
  • [ISO-abbreviation] Ann Pathol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Calbindin 2; 0 / S100 Calcium Binding Protein G
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11. Füredi G, Szilágyi A, Bencsik Z, Altorjay A: [Adenomatoid tumor of the adrenal gland. Case report and review of the literature]. Orv Hetil; 2007 Aug 19;148(33):1563-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Adenomatoid tumor of the adrenal gland. Case report and review of the literature].
  • [Transliterated title] A mellékvese adenomatoid tumora, avagy irodalmi barangolás egy igen ritka mesothelialis daganat nyomán.
  • Adenomatoid tumors of the adrenal gland are rather rare, asymptomatic neoplasias with benign behavior and usually are diagnosed incidentally.
  • The authors report a case of an adenomatoid tumor of the right adrenal gland in a 32-year-old man who sought evaluation because of fever and renal pain.
  • During investigation a tumor, localized in right adrenal gland, was identified by ultrasonography and CT.
  • The patient underwent adrenalectomy with histopathological and immunohistochemical diagnosis of adenomatoid tumor of the adrenal gland.
  • Based on literature data the epidemiology, symptoms, differential diagnosis, treatments, histopathology and prognosis of adenomatoid tumors of the adrenal gland are discussed.
  • [MeSH-major] Adenomatoid Tumor. Adrenal Gland Neoplasms
  • [MeSH-minor] Adrenalectomy. Adult. Biomarkers, Tumor / analysis. Diagnosis, Differential. Fever / etiology. Humans. Immunohistochemistry. Male. Pain / etiology. Tomography, X-Ray Computed

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  • (PMID = 17686675.001).
  • [ISSN] 0030-6002
  • [Journal-full-title] Orvosi hetilap
  • [ISO-abbreviation] Orv Hetil
  • [Language] hun
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Hungary
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 11
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12. Lehsnau M, Hecht L: [Adenomatoid tumor of the testes--a rare entity. Clinical, diagnostic and therapeutic aspects]. Urologe A; 2006 Nov;45(11):1431-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Adenomatoid tumor of the testes--a rare entity. Clinical, diagnostic and therapeutic aspects].
  • [Transliterated title] Adenomatoidtumor des Hodens--eine seltene Entität. Klinische, diagnostische und therapeutische Aspekte.
  • Adenomatoid tumor with intra-testicular localization is rare.
  • Adenomatoid tumors occur in both sexes and are also found in the uterus, ovary and fallopian tubes of the female genital tract.
  • Adenomatoid tumors are benign proliferations of mesothelial origin.
  • We report the case of a 50-year-old male with an adenomatoid tumor of the left testis.
  • [MeSH-major] Adenomatoid Tumor / diagnosis. Testicular Neoplasms / diagnosis
  • [MeSH-minor] Biomarkers, Tumor / analysis. Biopsy. Calbindin 2. Diagnosis, Differential. Humans. Keratins / analysis. Male. Middle Aged. Orchiectomy. Prognosis. S100 Calcium Binding Protein G / analysis. Testis / pathology. Tomography, X-Ray Computed. Ultrasonography. Vimentin / analysis

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  • (PMID = 16933122.001).
  • [ISSN] 0340-2592
  • [Journal-full-title] Der Urologe. Ausg. A
  • [ISO-abbreviation] Urologe A
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Calbindin 2; 0 / S100 Calcium Binding Protein G; 0 / Vimentin; 68238-35-7 / Keratins
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13. Canedo-Patzi AM, León-Bojorge B, de Ortíz-Hidalgo C: [Adenomatoid tumor of the genital tract. Clinical, pathological and immunohistochemical study in 9 cases]. Gac Med Mex; 2006 Jan-Feb;142(1):59-66
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Adenomatoid tumor of the genital tract. Clinical, pathological and immunohistochemical study in 9 cases].
  • [Transliterated title] Tumor adenomatoide del aparato genital, Estudio clinicopatológico e inmunohistoquímico de 9 casos.
  • OBJECTIVE: [corrected] Describe the histological andimmunohistochemicalfeatures of nine genital tract adenomatoid tumors.
  • MATERIAL AND METHODS: Nine cases of adenomatoid tumors were collected from the files of the Pathology department at a private hospital (ABC Hospital).
  • Tumors were studied from a histological and inmunohistochemical perspective.
  • Tumors were located in the uterus (seven),fallopian tube (one) and epididymis (one).
  • Tumor size ranged from 0.4 to 5.8 cm.
  • Arrangement of the neoplastic tubules around fascicles of smooth muscle; angiomatoidpattern with a peripheral location, and solid and adenoidpatterns with a central location in the tumor were some of the observed histological features.
  • Immunohistochemically all tumors exhibited strong and diffuse positivity for calretinin and AE1/AE3.
  • Thrombomodulin was positive in all tumors (focal and weak in angiomatoid pattern and diffuse and strong in adenoid and solid patterns).
  • The CK5/6 antibody was positive in seven tumors (diffuse in three and focal in four).
  • Two tumors were negative for this marker.
  • All tumors were negative for CD31.
  • CONCLUSIONS: The immunopheno type of the adenomatoid tumors in our series confirms their mesothelial origin.
  • [MeSH-major] Adenomatoid Tumor / pathology. Epididymis. Fallopian Tube Neoplasms / pathology. Genital Neoplasms, Male / pathology. Uterine Neoplasms / pathology

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  • (PMID = 16548294.001).
  • [ISSN] 0016-3813
  • [Journal-full-title] Gaceta médica de México
  • [ISO-abbreviation] Gac Med Mex
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Mexico
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14. Pauser U, Kosmahl M, Sipos B, Klöppel G: [Mesenchymal tumors of the pancreas. Surprising, but not uncommon]. Pathologe; 2005 Feb;26(1):52-8
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  • [Title] [Mesenchymal tumors of the pancreas. Surprising, but not uncommon].
  • Mesenchymal tumors of the pancreas are rare.
  • They are resected because a solid or cystic pancreatic tumor is suspected.
  • Benign mesenchymal tumors comprise lymphangiomas, hemangiomas, schwannomas, solitary fibrous tumors, adenomatoid tumors, clear cell tumors, and hamartomas.
  • Malignant mesenchymal tumors include leiomyosarcomas, malignant peripheral nerve sheath tumors (MPNST), liposarcomas, malignant fibrous histiocytomas, Ewing's sarcomas, and primitive neuroectodermal tumors (PNET).
  • It is important to differentiate these tumors from anaplastic carcinomas and retroperitoneal tumors that infiltrate pancreatic tissue.

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  • (PMID = 15592845.001).
  • [ISSN] 0172-8113
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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15. Burel-Vandenbos F, Cardot-Leccia N, Effi B, Varini JP, Saint-Paul MC, Michiels JF: [An unusual tumor of the adrenal gland]. Ann Pathol; 2005 Oct;25(5):386-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [An unusual tumor of the adrenal gland].
  • [Transliterated title] Une tumeur inhabituelle de la surrénale.
  • Adenomatoid tumors are benign mesothelial tumors that usually affect the genital tract.
  • We report the case of a 65-year-old man with an adenomatoid tumor of the adrenal gland.
  • This uncommon location and its histological heterogeneity can lead to a mistaken diagnosis of malignant tumor.
  • Positive cells with mesothelial markers in immunohistochemistry improve diagnosis.
  • The proper identification of this benign tumor in the adrenal gland and the knowledge of its differential diagnosis deserve attention to avoid invasive treatment.
  • [MeSH-major] Adenomatoid Tumor / pathology. Adrenal Gland Neoplasms / pathology
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adrenalectomy. Aged. Biomarkers, Tumor / analysis. Diagnosis, Differential. Humans. Lymphangioma / diagnosis. Male. Neoplasm Proteins / analysis

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  • (PMID = 16498291.001).
  • [ISSN] 0242-6498
  • [Journal-full-title] Annales de pathologie
  • [ISO-abbreviation] Ann Pathol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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16. Ghossain MA, Chucrallah A, Kanso H, Aoun NJ, Abboud J: Multilocular adenomatoid tumor of the ovary: ultrasonographic findings. J Clin Ultrasound; 2005 Jun;33(5):233-6
MedlinePlus Health Information. consumer health - Ovarian Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multilocular adenomatoid tumor of the ovary: ultrasonographic findings.
  • We report the sonographic findings of a rare benign ovarian tumor in a 69-year-old woman.
  • Surgery revealed an adenomatoid tumor.
  • Adenomatoid tumors are benign lesions of mesothelial origin, usually solid in nature and rarely located in the ovaries. (c) 2005 Wiley Periodicals, Inc.
  • [MeSH-major] Adenomatoid Tumor / ultrasonography. Ovarian Neoplasms / ultrasonography

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  • [Copyright] (c) 2005 Wiley Periodicals, Inc. J Clin Ultrasound 33:233-236, 2005.
  • (PMID = 16047378.001).
  • [ISSN] 0091-2751
  • [Journal-full-title] Journal of clinical ultrasound : JCU
  • [ISO-abbreviation] J Clin Ultrasound
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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17. Bhatt S, Rubens DJ, Dogra VS: Sonography of benign intrascrotal lesions. Ultrasound Q; 2006 Jun;22(2):121-36
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sonography of benign intrascrotal lesions.
  • Ultrasound plays an important role and adds essential information in diagnosing benign intrascrotal lesions.
  • Characterization of benign intrascrotal lesions with sonography, in combination with clinical assessment, can lead to nonsurgical management or testicular sparing surgery.
  • We present important sonographic features of benign intrascrotal lesions, including extratesticular lesions: adenomatoid tumors, papillary cystadenomas, spermatoceles, hydroceles, varicoceles, hernias; and intratesticular lesions: tunica albuginea cysts, testicular simple cysts, epidermoid cysts, tubular ectasia of the rete testis, intratesticular varicoceles, adrenal rest tumors, and splenogonadal fusion.
  • The goal of this review is to provide the radiologist with a better understanding of benign lesions that occur in the scrotum.

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  • (PMID = 16783242.001).
  • [ISSN] 0894-8771
  • [Journal-full-title] Ultrasound quarterly
  • [ISO-abbreviation] Ultrasound Q
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 73
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18. Varkarakis IM, Mufarrij P, Studeman KD, Jarrett TW: Adenomatoid of the adrenal gland. Urology; 2005 Jan;65(1):175
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid of the adrenal gland.
  • Adenomatoid tumors are common in the genital tract but rare in the adrenal gland.
  • These tumors can be difficult to diagnose when present in extragenital sites.
  • This type of adrenal tumor lacks specific radiographic features and can be confused preoperatively with more common adrenal gland tumors.
  • We present the case of a 54-year-old man with an incidental right adrenal mass with calcified components and elevated urinary levels of homovanillic acid that was found to be an adenomatoid tumor of the adrenal gland.
  • [MeSH-major] Adenomatoid Tumor / radiography. Adrenal Gland Neoplasms / radiography. Calcinosis / radiography
  • [MeSH-minor] Biomarkers, Tumor / analysis. Calbindin 2. Homovanillic Acid / urine. Humans. Incidental Findings. Kidney Calculi / complications. Kidney Calculi / radiography. Male. Middle Aged. Neoplasm Proteins / analysis. S100 Calcium Binding Protein G / analysis

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  • (PMID = 15667895.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Calbindin 2; 0 / Neoplasm Proteins; 0 / S100 Calcium Binding Protein G; X77S6GMS36 / Homovanillic Acid
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19. Ordóñez NG: Value of estrogen and progesterone receptor immunostaining in distinguishing between peritoneal mesotheliomas and serous carcinomas. Hum Pathol; 2005 Nov;36(11):1163-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Value of estrogen and progesterone receptor immunostaining in distinguishing between peritoneal mesotheliomas and serous carcinomas.
  • The differential diagnosis between peritoneal mesotheliomas and serous carcinomas involving the peritoneum may be difficult, but it can be facilitated by the use of immunohistochemistry.
  • To determine whether estrogen receptors (ER) or progesterone receptors (PR) may have any value as immunohistochemical markers for discriminating between these malignancies, 40 serous carcinomas of the ovary metastatic to the peritoneum, 7 primary peritoneal serous carcinomas, 30 epithelioid peritoneal malignant mesotheliomas, 5 well-differentiated papillary mesotheliomas, and 4 adenomatoid tumors were immunostained for ER and PR.
  • None of the mesotheliomas or adenomatoid tumors expressed ER or PR.
  • It is concluded that, because of its high sensitivity for serous carcinomas, ER immunostaining could be very useful in distinguishing between serous carcinomas and peritoneal mesotheliomas.
  • [MeSH-major] Biomarkers, Tumor / analysis. Cystadenocarcinoma, Serous / diagnosis. Mesothelioma / diagnosis. Peritoneal Neoplasms / diagnosis. Receptors, Estrogen / metabolism. Receptors, Progesterone / metabolism

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  • [CommentIn] Hum Pathol. 2005 Nov;36(11):1153 [16260266.001]
  • (PMID = 16260268.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
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20. Acikalin MF, Tanir HM, Ozalp S, Dundar E, Ciftci E, Ozalp E: Diffuse uterine adenomatoid tumor in a patient with chronic hepatitis C virus infection. Int J Gynecol Cancer; 2009 Feb;19(2):242-4
MedlinePlus Health Information. consumer health - Uterine Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diffuse uterine adenomatoid tumor in a patient with chronic hepatitis C virus infection.
  • Uterine adenomatoid tumors are usually solitary lesions.
  • Adenomatoid tumors diffusely infiltrating the entire myometrium have rarely been reported in the literature.
  • A feature common to half of the reported cases of diffuse uterine adenomatoid tumor was an immunocompromised status of the patient caused by the medications for renal transplantation.
  • In this article, we describe an unusual case of diffuse uterine adenomatoid tumor in a patient with chronic hepatitis C virus infection.
  • Pathological examination showed, in addition to multiple leiomyomas, diffuse uterine adenomatoid tumor.
  • [MeSH-major] Adenomatoid Tumor / immunology. Hepatitis C, Chronic / immunology. Immunocompromised Host. Uterine Neoplasms / immunology

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  • (PMID = 19396001.001).
  • [ISSN] 1525-1438
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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21. González Resina R, Carranza Carranza A, Congregado Córdoba J, Conde Sánchez JM, Congregado Ruiz CB, Medina López R: [Paratesticular adenomatoid tumor: a report of nine cases]. Actas Urol Esp; 2010 Jan;34(1):95-100

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Paratesticular adenomatoid tumor: a report of nine cases].
  • [Transliterated title] Tumor adenomatoide paratesticular: una serie de nueve casos.
  • INTRODUCTION: Paratesticular tumors are rare.
  • Most of them are benign, and adenomatoid tumors are most common.
  • These tumors sometimes infiltrate the testicular parenchyma and require differential diagnosis with malignant tumors.
  • MATERIALS AND METHODS: A retrospective study of nine patients with paratesticular adenomatoid tumors seen during a nine-year period (2000-2008) is reported.
  • The tumor most commonly occurred as a small, usually oval, nodule in the tail of epididymis.
  • Our series included a case each of intraparenchymal tumor of the testis and tumor of the tunica vaginalis.
  • [MeSH-major] Adenomatoid Tumor / pathology. Epididymis / pathology. Genital Neoplasms, Male / pathology
  • [MeSH-minor] Adult. Calbindin 2. Diagnosis, Differential. Humans. Keratins / analysis. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Proteins / analysis. Retrospective Studies. S100 Calcium Binding Protein G / analysis. Testis / pathology

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  • (PMID = 20223139.001).
  • [ISSN] 1699-7980
  • [Journal-full-title] Actas urologicas españolas
  • [ISO-abbreviation] Actas Urol Esp
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Calbindin 2; 0 / Neoplasm Proteins; 0 / S100 Calcium Binding Protein G; 68238-35-7 / Keratins
  • [Number-of-references] 13
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22. Lee JC, Bhatt S, Dogra VS: Imaging of the epididymis. Ultrasound Q; 2008 Mar;24(1):3-16

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Ultrasonography performed with a high-frequency transducer is the modality of choice for evaluating acute and nonacute scrotal disease.
  • Features of benign and malignant epididymal lesions, including epididymal cysts, spermatoceles and tubular ectasia, sperm granulomas, adenomatoid tumors, leiomyomas, papillary cyst adenomas, lymphoma, and metastases are also presented.

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  • (PMID = 18362528.001).
  • [ISSN] 0894-8771
  • [Journal-full-title] Ultrasound quarterly
  • [ISO-abbreviation] Ultrasound Q
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 69
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23. Sieunarine K, Cowie AS, Bartlett JD, Lindsay I, Smith JR: A novel approach in the management of a recurrent adenomatoid tumor of the uterus utilizing a Strassman technique. Int J Gynecol Cancer; 2005 Jul-Aug;15(4):671-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A novel approach in the management of a recurrent adenomatoid tumor of the uterus utilizing a Strassman technique.
  • Adenomatoid tumors of the uterus are uncommon benign lesions derived from mesothelium, with a prevalence of 1.2% in one study of 1 000 unselected hysterectomy specimens.
  • They are usually small and near the serosal surface; however, they may be large and diffuse (giant adenomatoid tumors).
  • This transpired to be an adenomatoid tumor, and she underwent three transcervical resections of the tumor (TCRT) over a period of 12 months for tumor recurrence and failure of symptom resolution.
  • A specialist opinion on the suitability of vascular embolization of the tumor judged that it would be ineffective for this lesion.
  • She then underwent a Strassman procedure and removal of the adenomatoid tumor.
  • This involved dissection of ureters and pelvic vasculature, selective temporary ligation of uterine arteries, hemisection of the uterus, and excision of the tumor with frozen sections to ensure clear tumor margins and resuturing of the uterine halves.
  • Temporary vascular occlusion of the uterine arteries and ovarian vessels allowed a Strassman procedure, which resulted in successful resection of a recurrent giant adenomatoid tumor of the uterus, with fertility preservation in a young nulliparous woman.
  • Two and a half years on there is no evidence of tumor recurrence.
  • [MeSH-major] Adenomatoid Tumor / surgery. Gynecologic Surgical Procedures / methods. Neoplasm Recurrence, Local / surgery. Uterine Neoplasms / surgery. Uterus / blood supply

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  • (PMID = 16014122.001).
  • [ISSN] 1048-891X
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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24. Soini Y, Talvensaari-Mattila A: Expression of claudins 1, 4, 5, and 7 in ovarian tumors of diverse types. Int J Gynecol Pathol; 2006 Oct;25(4):330-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of claudins 1, 4, 5, and 7 in ovarian tumors of diverse types.
  • Strong expression of claudins 1, 4, and 7 was seen in benign and malignant epithelial ovarian tumors.
  • Expression of claudin 5, reported to be mainly present in endothelial cells, was seen in ovarian epithelial tumors, but with a significantly lower frequency than claudins 1, 4, and 7.
  • On the contrary, sex-cord stromal tumors and cysts, such as fibromas/thecomas, Sertoli-Leydig cell tumors, granulosa cell tumors, and follicular and luteinized cysts were mainly negative for claudins 1, 4, 5, and 7.
  • Interestingly, adenomatoid tumors did not express claudin 5, which is in agreement with their non-endothelial nature.
  • They were also negative for claudin 4, but expressed claudins 1 and 7, but to a lesser degree than epithelial lesions.
  • In immature teratomas, the epithelial component was usually positive whereas other components were negative for these claudins.
  • The results show that claudins 1, 4, and 7 are mainly expressed in ovarian epithelial tumors and can thus be used to indicate epithelial differentiation in them.
  • Eventhough considered an endothelial marker, claudin 5 was also present in a subset of epithelial lesions.
  • However, this claudin can be used to differentiate adenomatoid tumors from vascular lesions.
  • No significant difference was seen between epithelial benign and malignant lesions, except for claudin 5, which seemed stronger in malignant epithelial tumors.
  • [MeSH-minor] Adenomatoid Tumor / chemistry. Brenner Tumor / chemistry. Carcinoma / chemistry. Claudin-1. Claudin-4. Claudin-5. Claudins. Dysgerminoma / chemistry. Female. Humans. Immunohistochemistry. Krukenberg Tumor / chemistry. Ovarian Cysts. Sex Cord-Gonadal Stromal Tumors / chemistry. Teratoma / chemistry

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  • (PMID = 16990707.001).
  • [ISSN] 0277-1691
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CLDN1 protein, human; 0 / CLDN4 protein, human; 0 / CLDN5 protein, human; 0 / CLDN7 protein, human; 0 / Claudin-1; 0 / Claudin-4; 0 / Claudin-5; 0 / Claudins; 0 / Membrane Proteins
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25. Ordóñez NG: D2-40 and podoplanin are highly specific and sensitive immunohistochemical markers of epithelioid malignant mesothelioma. Hum Pathol; 2005 Apr;36(4):372-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] D2-40 and podoplanin are highly specific and sensitive immunohistochemical markers of epithelioid malignant mesothelioma.
  • The observation that both of these markers are also expressed in normal and reactive mesothelial cells prompted an investigation into their potential value in the diagnosis of mesotheliomas.
  • To determine whether podoplanin and D2-40 had any use in the diagnosis of these tumors, 40 mesotheliomas (29 epithelioid, 5 biphasic, and 6 sarcomatoid), 34 carcinomas of the lung (24 adenocarcinomas, 10 squamous carcinomas), 80 nonpulmonary adenocarcinomas (17 ovary, 10 breast, 10 colon, 10 kidney, 5 endometrium, 5 stomach, 5 pancreas, 5 prostate, 3 thyroid), 12 synovial sarcomas (6 biphasic and 6 monophasic), 5 angiosarcomas, and 2 adenomatoid tumors were immunostained with a monoclonal antibody to podoplanin and with the D2-40 antibody.
  • Reactivity for both D2-40 and podoplanin was obtained in 25 (86%) of the 29 epithelioid mesotheliomas but in none of the carcinomas or sarcomatoid mesotheliomas.
  • Positivity for D2-40 and podoplanin was also seen in the epithelioid components of 4 of 5 biphasic mesotheliomas and 4 of 6 synovial sarcomas, whereas the spindle cell components of these tumors were negative as were the monophasic synovial sarcomas.
  • Both of the adenomatoid tumors were also positive for D2-40 and podoplanin, a finding which provides further support for the mesothelial derivation of these tumors.
  • It is concluded that, because of their high specificity and sensitivity for epithelioid mesotheliomas, D2-40 and podoplanin are very useful markers for the diagnosis of these tumors.
  • [MeSH-major] Antibodies, Monoclonal / analysis. Membrane Glycoproteins / analysis. Mesothelioma / diagnosis
  • [MeSH-minor] Antibodies, Monoclonal, Murine-Derived. Antigens, Neoplasm / immunology. Biomarkers, Tumor. Female. Humans. Immunohistochemistry. Male. Sensitivity and Specificity

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  • (PMID = 15891998.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Membrane Glycoproteins; 0 / PDPN protein, human; 0 / monoclonal antibody D2-40; 0 / oncofetal antigens
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26. Garrido Abad P, Jiménez Gálvez M, Herranz Fernández LM, Bocardo Fajardo G, Arellano Gañán R, Pereira Sanz I: [Adenomatoid tumor of the epididymis. Report of two cases]. Arch Esp Urol; 2007 Jul-Aug;60(6):700-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Adenomatoid tumor of the epididymis. Report of two cases].
  • [Transliterated title] Tumor adenomatoide de epidídimo. Aportación de dos casos.
  • OBJECTIVE: Tumors of the epididymis are rare.
  • They are unusually benign and adenomatoid tumors are the most frequent.
  • Report of two cases of this kind of tumor of the epididymis.
  • METHODS/RESULTS: We report two cases of adenomatoid tumor of the epididymis diagnosed at our hospital during last year.
  • Pathological diagnosis was adenomatoid tumor.
  • CONCLUSIONS: The majority of epididymal tumors follow a benign course.
  • In the finding of an epididymal mass, after palpation and imaging tests, organ sparing surgery (epididymectomy) is recommended.
  • [MeSH-major] Adenomatoid Tumor. Epididymis. Genital Neoplasms, Male

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  • (PMID = 17847749.001).
  • [ISSN] 0004-0614
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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27. Tursi M, Martinetti M, Gili S, Muscio M, Gay L, Crudelini M, Cenacchi G, Pucci A: Myocardial adenomatoid tumor in eight cattle: evidence for mesothelial origin of bovine myocardial epithelial inclusions. Vet Pathol; 2009 Sep;46(5):897-903
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Myocardial adenomatoid tumor in eight cattle: evidence for mesothelial origin of bovine myocardial epithelial inclusions.
  • The adenomatoid tumor is an uncommon benign lesion, thus far described only in humans.
  • Adenomatoid tumors typically arise in the genital tract, exceptionally in the heart, and usually represent an incidental finding.
  • Mesothelial origin of these lesions is suggested by their immunohistochemical characteristics.
  • In cattle, previously reported myocardial epithelial inclusions are morphologically similar in that the cells are immunoreactive for both cytokeratins and vimentin, and bear surface microvilli.
  • Myocardial lesions found incidentally at slaughter in 8 cattle histologically resembled the so-called bovine myocardial epithelial inclusions and had morphologic and immunohistochemical features consistent with human adenomatoid tumor.
  • All lesions were in the left ventricular myocardium, adjacent to the epicardium, and composed of epithelioid cells that formed cords and tubules, and were immunoreactive for pan-cytokeratins, cytokeratin 5/6, vimentin, calretinin, Wilms' tumor 1 suppressor gene, and CD30 antigen.
  • The immunohistochemical and ultrastructural features were considered consistent with mesothelial origin.
  • These lesions, corresponding to the previously described myocardial epithelial inclusions in cattle, might be considered embryologic rests and could represent the bovine counterpart of the human adenomatoid tumor.
  • [MeSH-major] Adenomatoid Tumor / veterinary. Cattle Diseases / pathology. Heart Neoplasms / veterinary. Neoplasms, Mesothelial / veterinary

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  • (PMID = 19430001.001).
  • [ISSN] 1544-2217
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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28. Bestard Vallejo JE, Tremps Velázquez E, Blázquez Mañá C, Celma Doménech A, de Torres Ramírez I, Morote Robles J: [Adenomatoid tumour of epididymis: the most common tumour of the paratesticular structures]. Actas Urol Esp; 2008 Jun;32(6):611-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Adenomatoid tumour of epididymis: the most common tumour of the paratesticular structures].
  • [Transliterated title] Tumor adenomatoide de epididimo: el tumor más frecuente de las estructuras paratesticulares.
  • INTRODUCTION: Paratesticular tumours are rare but generally benign neoplasms, usually treated by local excission.
  • Adenomatoid tumours of epididymis are the most common of these tumours.
  • OBJECTIVES: Analyze paratesticular tumours treated in our center and describe dyagnosis and treatment of adenomatoid tumours of epididymis.
  • MATERIAL AND METHODS: We retrospectively review 8 patients with paratesticular tumours treated from July 1997 to July 2007.
  • RESULTS: Patients median age was 44.1 years (22-69), presenting most of them subacute scrotal tumour with median size by ultrasound of 2.8 cm (1.5-7).
  • All of them were locally extirpated except one with suspicion of a malignant polyorchidism and another one with an apparently intratesticular lesion of great size.
  • Dyagnosis was in 4 cases adenomatoid tumour of epididymis, in two cases fibrous pseudotumour of epididymis, in one case leiomyoma of epididymis and in one case angiolipoma of spermatic cord.
  • Just in one case diagnosed of adenomatoid tumour of epididymis ultrasound confirmed solid tumour suggesting the final dyagnosis.
  • CONCLUSIONS: Adenomatoid tumors of epididymis are rare tumours which may present at any age.
  • Benignity of adenomatoid tumour of epididymis as well as most of the other paratesticular tumours should make local excission the treatment of choice and, when any doubt existed, peroperatory biopsy should be performed.
  • [MeSH-major] Adenomatoid Tumor. Epididymis. Genital Neoplasms, Male

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  • (PMID = 18655344.001).
  • [ISSN] 0210-4806
  • [Journal-full-title] Actas urologicas españolas
  • [ISO-abbreviation] Actas Urol Esp
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 19
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29. Bisceglia M, Carosi I, Scillitani A, Pasquinelli G: Cystic lymphangioma-like adenomatoid tumor of the adrenal gland: Case presentation and review of the literature. Adv Anat Pathol; 2009 Nov;16(6):424-32
The Weizmann Institute of Science GeneCards and MalaCards databases. gene/protein/disease-specific - MalaCards for adenomatoid tumor .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cystic lymphangioma-like adenomatoid tumor of the adrenal gland: Case presentation and review of the literature.
  • Adenomatoid tumors (AT) are usually found in the genital tract of both sexes.
  • Thirty-four cases have been reported so far, more often presenting grossly as solid tumors, rarely as solid with cystic areas, and 5 cases were almost entirely cystic.
  • On light microscopy the diagnosis may be very difficult if the tumor is rich in vacuolated cells, mimicking metastatic signet ring-cell adenocarcinoma.
  • Immunophenotyping and/or electron microscopy are paramount in helping to ascertain their mesothelial lineage.
  • Lymphangioma is the main histologic mimic of solid-cystic and cystic AT-AG, but lymphangioma is immunopositive for endothelial markers and negative for cytokeratins and mesothelial markers.
  • The adrenal tumor was 5.5 cm in size and was fully investigated immunohistochemically and ultrastructurally.
  • [MeSH-major] Adenomatoid Tumor / pathology. Adrenal Gland Neoplasms / pathology. Lymphangioma, Cystic / pathology

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  • (PMID = 19851133.001).
  • [ISSN] 1533-4031
  • [Journal-full-title] Advances in anatomic pathology
  • [ISO-abbreviation] Adv Anat Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 39
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30. Arunaa S, Ponniah I: Distribution pattern of the adenomatoid odontogenic tumor: a retrospective study from the files of a government teaching hospital, Tamil Nadu, Chennai, India. J Investig Clin Dent; 2010 Aug;1(1):23-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Distribution pattern of the adenomatoid odontogenic tumor: a retrospective study from the files of a government teaching hospital, Tamil Nadu, Chennai, India.
  • AIM: To determine the distribution and clinicopathologic characteristics of adenomatoid odontogenic tumors from Tamil Nadu, India, to provide meaningful data for comparison among different population groups, mainly in the Asian context.
  • METHODS: Forty-three adenomatoid odontogenic tumors were reviewed from 493 odontogenic tumors recorded between 1970 and 2008.
  • The data pertaining to age, sex, anatomic site, associated impacted teeth and radiographic details, provisional diagnoses, and macroscopic and microscopic details of the 43 odontogenic tumors were reviewed.
  • RESULTS: The relative frequency of adenomatoid tumors comprised 8.72% of the total odontogenic tumors.
  • The age range was 9-30 years, with a mean age of 16.88 years for combined adenomatoid odontogenic tumors.
  • The mean age for other variants of adenomatoid odontogenic tumors assessed in this study differed slightly between sexes.
  • For combined adenomatoid odontogenic tumors, the male-to-female ratio was 1:1.26, and the maxilla-to-mandible ratio was 2.9:1.
  • CONCLUSION: The present study shows variations in the distribution of adenomatoid odontogenic tumors within the population assessed, but no definite conclusion emerged with regard to regional or ethnic effect.
  • [MeSH-major] Odontogenic Tumors / epidemiology

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  • [Copyright] © 2010 Blackwell Publishing Asia Pty Ltd.
  • (PMID = 25427183.001).
  • [ISSN] 2041-1626
  • [Journal-full-title] Journal of investigative and clinical dentistry
  • [ISO-abbreviation] J Investig Clin Dent
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
  • [Keywords] NOTNLM ; Asian / Dravidian / India / Tamil Nadu / adenomatoid odontogenic tumor
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31. Inamoto T, Yamada T, Ohnuma K, Kina S, Takahashi N, Yamochi T, Inamoto S, Katsuoka Y, Hosono O, Tanaka H, Dang NH, Morimoto C: Humanized anti-CD26 monoclonal antibody as a treatment for malignant mesothelioma tumors. Clin Cancer Res; 2007 Jul 15;13(14):4191-200
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Humanized anti-CD26 monoclonal antibody as a treatment for malignant mesothelioma tumors.
  • PURPOSE: CD26 is a 110-kDa cell surface antigen with a role in tumor development.
  • In this report, we show that CD26 is highly expressed on the cell surface of malignant mesothelioma and that a newly developed humanized anti-CD26 monoclonal antibody (mAb) has an inhibitory effect on malignant mesothelioma cells in both in vitro and in vivo experiments.
  • EXPERIMENTAL DESIGN: Using immunohistochemistry, 12 patients' surgical specimens consisting of seven malignant mesothelioma, three reactive mesothelial cells, and two adenomatoid tumors were evaluated for expression of CD26.
  • The effects of CD26 on malignant mesothelioma cells were assessed in the presence of transfection of CD26-expressing plasmid, humanized anti-CD26 mAb, or small interfering RNA against CD26.
  • The in vivo growth inhibitory effect of humanized anti-CD26 mAb was assessed in human malignant mesothelioma cell mouse xenograft models.
  • RESULTS: In surgical specimens, CD26 is highly expressed in malignant mesothelioma but not in benign mesothelial tissues.
  • Moreover, our in vitro data indicate that humanized anti-CD26 mAb induces cell lysis of malignant mesothelioma cells via antibody-dependent cell-mediated cytotoxicity in addition to its direct anti-tumor effect via p27(kip1) accumulation.
  • In vivo experiments with mouse xenograft models involving human malignant mesothelioma cells show that humanized anti-CD26 mAb treatment drastically inhibits tumor growth in tumor-bearing mice, resulting in enhanced survival.
  • CONCLUSIONS: Our data strongly suggest that humanized anti-CD26 mAb treatment may have potential clinical use as a novel cancer therapeutic agent in CD26-positive malignant mesothelioma.
  • [MeSH-major] Antibodies, Monoclonal / therapeutic use. Dipeptidyl Peptidase 4 / immunology. Lung Neoplasms / immunology. Mesothelioma / immunology
  • [MeSH-minor] Antigens, CD / genetics. Antigens, CD / immunology. Humans. Immunity, Cellular. Immunohistochemistry. Immunotherapy. Tumor Cells, Cultured

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  • (PMID = 17634548.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antigens, CD; EC 3.4.14.5 / Dipeptidyl Peptidase 4
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32. Cao D, Li J, Guo CC, Allan RW, Humphrey PA: SALL4 is a novel diagnostic marker for testicular germ cell tumors. Am J Surg Pathol; 2009 Jul;33(7):1065-77
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] SALL4 is a novel diagnostic marker for testicular germ cell tumors.
  • The diagnosis of testicular germ cell tumors (GCTs) sometimes can be challenging without ancillary markers.
  • Here we performed an immunohistochemical study of a novel stem cell marker SALL4 in a large series of 110 primary testicular GCTs (65 pure and 45 mixed) containing the following types of tumors and/or tumor components: 50 intratubular germ cell neoplasias (ITGCNs), 62 classic seminomas, 2 spermatocytic seminomas, 39 embryonal carcinomas (EC), 5 pediatric and 26 postpubertal yolk sac tumors (YST), 7 pediatric and 25 postpubertal teratomas, and 5 choriocarcinomas.
  • To test SALL4 specificity, 23 testicular non-GCTs (10 Leydig cell tumors, 4 Sertoli cell tumors, 3 adenomatoid tumors, 3 paratesticular rhabdomyosarcomas, 2 diffuse large B-cell lymphomas, and 1 rete testis papillary cystadenoma) and 275 nontesticular tumors (158 metastatic carcinomas, 12 metastatic melanomas, 11 primary and 2 metastatic mesotheliomas, and 72 primary and 20 metastatic sarcomas) were also stained for SALL4.
  • All ITGCNs, classic seminomas, and ECs demonstrated strong SALL4 and OCT4 staining in more than 90% tumor cells.
  • All 31 YSTs (5 pediatric and 26 postpubertal) showed strong positive SALL4 staining in more than 90% tumor cells but had negative OCT4 staining.
  • Both spermatocytic seminomas showed positive SALL4 staining in 80% to 95% tumor cells in all 3 types of tumor cells with weak-to-moderate staining intensity.
  • Of 275 nontesticular tumors, only 10 carcinomas and 1 sarcoma showed focal (<25% tumor cells) weak SALL4 staining.
  • Although all 31 YSTs showed glypican-3 staining, 14 (45%) show staining in less than 30% tumor cells.
  • [MeSH-major] Biomarkers, Tumor / analysis. Neoplasms, Germ Cell and Embryonal / diagnosis. Testicular Neoplasms / diagnosis. Transcription Factors / biosynthesis

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  • (PMID = 19390421.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / SALL4 protein, human; 0 / Transcription Factors
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33. Sollami S, Ben Salah I, Chelif M, Hafsia G, Ben Rhouma S, Nouira Y, Horchani A: [Intrascrotal adenomatoid tumors]. Tunis Med; 2008 Jun;86(6):626

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Intrascrotal adenomatoid tumors].
  • [MeSH-major] Adenomatoid Tumor / pathology. Epididymis. Genital Neoplasms, Male / pathology. Scrotum

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  • (PMID = 19216473.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Tunisia
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34. Moyano Calvo JL, Giraldez Puig J, Sánchez de la Vega J, Dávalos Casanova G, Morales López A: [Adenomatoid tumor of the epididymis]. Actas Urol Esp; 2007 Apr;31(4):417-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Adenomatoid tumor of the epididymis].
  • [Transliterated title] Tumor adenomatoide de epididimo.
  • OBJECTIVE: Paratesticular tumors are very rare and mostly bening.
  • Wa aport a new case of adenomatoid tumor of epididymis METHOD: Male of 40 years old with solid lesion in epidididymis tale treated with mass exéresis RESULTS: Adenoamotid tumor of the epididymis confirmed with hystopathologic technique CONCLUSION: Adenomatoid tumor of epididymis is the most frequent paratesticular tumors and when is suspected, conservative surgery must be performed.
  • [MeSH-major] Adenomatoid Tumor. Epididymis. Genital Neoplasms, Male

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  • (PMID = 17633930.001).
  • [ISSN] 0210-4806
  • [Journal-full-title] Actas urologicas españolas
  • [ISO-abbreviation] Actas Urol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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35. Pila Pérez R, Rosales Torres P, Pila Peláez R, Holguín Prieto V, Torres Vargas E: [Adenomatoid tumor of the epididymis: an infrequent case]. Arch Esp Urol; 2009 Oct;62(8):656-60

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Adenomatoid tumor of the epididymis: an infrequent case].
  • [Transliterated title] Tumor adenomatoide del epidídimo: una infrecuente observación.
  • OBJECTIVES: To present a new case of adenomatoid tumor of the epididymis, the first report in our hospital since 1962.
  • METHODS: We report a clinical case with a brief bibliographic review about adenomatoid tumor of the epididymis.
  • Physical examination and ultrasound study demonstrated a tumor of 5x5x2 cm.
  • It was removed and the histopathological study was compatible with adenomatoid tumor of the epididymis.
  • CONCLUSION: The adenomatoid tumor of the epididymis is a neoplasm located in the paratesticular region, however it can be found infrequently in other sites.
  • Mesothelial origin has been mentioned and inflammation has played some role in the development of these tumors.
  • It can minimally invade adjacent structures, though it is benign without metastatic potential.
  • [MeSH-major] Adenomatoid Tumor. Epididymis. Genital Neoplasms, Male

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  • (PMID = 19893140.001).
  • [ISSN] 1576-8260
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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36. Ribeiro BF, Iglesias DP, Nascimento GJ, Galvão HC, Medeiros AM, Freitas RA: Immunoexpression of MMPs-1, -2, and -9 in ameloblastoma and odontogenic adenomatoid tumor. Oral Dis; 2009 Oct;15(7):472-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Immunoexpression of MMPs-1, -2, and -9 in ameloblastoma and odontogenic adenomatoid tumor.
  • OBJECTIVE: The aim of this study was to evaluate and compare the expression of metalloproteinases-1, -2, and -9 in solid ameloblastoma and adenomatoid odontogenic tumor.
  • METHODS: A total of 20 cases of solid ameloblastoma and 10 cases of adenomatoid odontogenic tumors were selected and immunohistochemically assessed.
  • RESULTS: Matrix metalloproteinase (MMP)-1 showed a predominant expression in both tumors and was found in stroma and parenchyma.
  • For MMP-2, there was a varied expression, with 80% and 60% of immunoreactive tumor cells in ameloblastoma and adenomatoid odontogenic tumor respectively.
  • Regarding stromal cells, 65% of ameloblastomas and 80% of adenomatoid odontogenic tumors showed positivity.
  • There was immunoexpression of the MMP-9 in parenchymal and stromal cells in all cases of both tumors analyzed.
  • CONCLUSION: The results suggest that these metalloproteinases are related to growth and progression of tumors analyzed, and particularly in ameloblastoma, its highest aggressiveness may be, in part, a result of the active participation of the stromal cells and their products, such as the MMPs studied.
  • [MeSH-major] Ameloblastoma / metabolism. Matrix Metalloproteinase 1 / biosynthesis. Matrix Metalloproteinase 2 / biosynthesis. Matrix Metalloproteinase 9 / biosynthesis. Odontogenic Tumors / metabolism

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  • (PMID = 19522745.001).
  • [ISSN] 1601-0825
  • [Journal-full-title] Oral diseases
  • [ISO-abbreviation] Oral Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] EC 3.4.24.24 / Matrix Metalloproteinase 2; EC 3.4.24.35 / Matrix Metalloproteinase 9; EC 3.4.24.7 / Matrix Metalloproteinase 1
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37. Timonera ER, Paiva ME, Lopes JM, Eloy C, van der Kwast T, Asa SL: Composite adenomatoid tumor and myelolipoma of adrenal gland: report of 2 cases. Arch Pathol Lab Med; 2008 Feb;132(2):265-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Composite adenomatoid tumor and myelolipoma of adrenal gland: report of 2 cases.
  • Adenomatoid tumor and myelolipoma are benign, hormonally inactive tumors that are often incidental findings in the adrenal glands.
  • Myelolipoma is more common than adenomatoid tumor in this location but both are rare, and as yet, the pathogenesis of both remains unclear.
  • We report 2 cases of composite adenomatoid tumor and myelolipoma, incidentally found in the adrenal gland on investigation for other diseases.
  • To our knowledge, composite adenomatoid tumor and myelolipoma of adrenal gland has not been previously reported.

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  • (PMID = 18251587.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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38. Schirmer I, Reichart PA: [Adenomatoid odontogenic tumor (AOT) of the mandible: a surgical follow-up]. Mund Kiefer Gesichtschir; 2007 Nov;11(5):291-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Adenomatoid odontogenic tumor (AOT) of the mandible: a surgical follow-up].
  • [Transliterated title] Chirurgische Verlaufsbeobachtung eines adenomatoid odontogenen Tumors (AOT) im Unterkiefer: Ein Fallbericht.
  • The AOT is a relative rare benign odontogenic tumor.
  • The histological diagnosis of an AOT was only revealed after a second operation including tumor removal.
  • [MeSH-major] Mandibular Neoplasms / surgery. Odontogenic Tumors / surgery

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  • [Cites] Oral Oncol. 1999 Mar;35(2):125-31 [10435145.001]
  • [Cites] J Oral Pathol Med. 2007 Aug;36(7):383-93 [17617830.001]
  • [Cites] J Oral Pathol Med. 1991 Apr;20(4):149-58 [2061853.001]
  • [Cites] Acta Pathol Microbiol Scand. 1969;75(3):375-98 [5801660.001]
  • (PMID = 17828424.001).
  • [ISSN] 1432-9417
  • [Journal-full-title] Mund-, Kiefer- und Gesichtschirurgie : MKG
  • [ISO-abbreviation] Mund Kiefer Gesichtschir
  • [Language] ger
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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39. Monappa V, Rao AC, Krishnanand G, Mathew M, Garg S: Adenomatoid tumor of tunica albuginea mimicking seminoma on fine needle aspiration cytology: a case report. Acta Cytol; 2009 May-Jun;53(3):349-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid tumor of tunica albuginea mimicking seminoma on fine needle aspiration cytology: a case report.
  • BACKGROUND: Adenomatoid tumor is one of the most common primary neoplasms of the paratesticular area.
  • Review of the literature showed very few reports on the cytologic features of adenomatoid tumor.
  • We report the cytologic features of a case of adenomatoid tumor arising from testicular tunica albuginea.
  • Histopathologic examination confirmed the diagnosis as adenomatoid tumor of tunica albuginea.
  • CONCLUSION: FNAC of an adenomatoid tumor poses a diagnostic challenge when the tumor arises from sites other than the epididymis because they can be mistaken for intratesticular tumors.
  • It is thus important to consider this tumor in the differential diagnosis of scrotal swellings.
  • [MeSH-major] Adenomatoid Tumor / pathology. Seminoma / pathology. Testicular Neoplasms / pathology
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / secondary. Adult. Biopsy, Fine-Needle. Cystadenoma, Papillary / diagnosis. Diagnosis, Differential. Epithelium / pathology. Humans. Hyperplasia / diagnosis. Male. Mesothelioma / diagnosis. Orchiectomy

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  • (PMID = 19534283.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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40. Rappa F, Ternullo MP: [Adenomatoid tumor]. Pathologica; 2006 Apr;98(2):164-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Adenomatoid tumor].
  • [Transliterated title] Tumore adenomatoide.
  • Adenomatoid tumour is a neoplastic process of discussed origin, but the immunohistochemical phenotype leads a mesothelial derivation.
  • In the present report we described a case of Adenomatoid tumour of the uterus body in a 46 years old patient.
  • [MeSH-major] Adenomatoid Tumor / pathology. Uterine Neoplasms / pathology
  • [MeSH-minor] Actins / analysis. Calbindin 2. Diagnosis, Differential. Female. Humans. Immunoenzyme Techniques. Keratins / analysis. Leiomyoma / diagnosis. Middle Aged. Neoplasm Proteins / analysis. S100 Calcium Binding Protein G / analysis. Staining and Labeling

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  • (PMID = 16929792.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Actins; 0 / Calbindin 2; 0 / Neoplasm Proteins; 0 / S100 Calcium Binding Protein G; 68238-35-7 / Keratins
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41. Bandier PC, Hansen A, Thorelius L: [Adenomatoid tumour of the adrenal gland]. Ugeskr Laeger; 2009 Jan 26;171(5):306-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Adenomatoid tumour of the adrenal gland].
  • [Transliterated title] Adenomatoid tumor i binyre.
  • An adenomatoid tumour in the right suprarenal gland was discovered during clinical cancer staging of a 73-year-old woman.
  • Adenomatoid tumours in the suprarenal glands are rare and are most often found incidentally.
  • Differential diagnoses comprise malignant vascular neoplasm or adenocarcinoma.
  • Immunohistochemistry or electron microscopy allows uncomplicated distinction between these tumours.
  • [MeSH-major] Adenomatoid Tumor / pathology. Adrenal Gland Neoplasms / pathology

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  • [CommentIn] Ugeskr Laeger. 2009 Mar 16;171(12):1015; author reply 1015 [19306484.001]
  • (PMID = 19176156.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Denmark
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42. Phillips V, McCluggage WG, Young RH: Oxyphilic adenomatoid tumor of the ovary: a case report with discussion of the differential diagnosis of ovarian tumors with vacuoles and related spaces. Int J Gynecol Pathol; 2007 Jan;26(1):16-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Oxyphilic adenomatoid tumor of the ovary: a case report with discussion of the differential diagnosis of ovarian tumors with vacuoles and related spaces.
  • We describe an unusual example of ovarian adenomatoid tumor that was an incidental finding in the ovary of a 52-year-old woman and was characterized by cells with abundant eosinophilic cytoplasm, an occasional feature of the adenomatoid tumor but one that, in an ovarian example, may cause added diagnostic confusion to that already engendered by the rarity of this neoplasm in the ovary.
  • The typical numerous small vacuoles of the neoplasm sometimes had the appearance of signet ring cells.
  • Tumor cells were positive with broad-spectrum cytokeratins as well as mesothelial markers CK5/6, WT1, and calretinin.
  • [MeSH-major] Adenomatoid Tumor / diagnosis. Ovarian Neoplasms / diagnosis

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  • (PMID = 17197891.001).
  • [ISSN] 0277-1691
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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43. Vargas PA, Carlos-Bregni R, Mosqueda-Taylor A, Cuairan-Ruidíaz V, Lopes MA, de Almeida OP: Adenomatoid dentinoma or adenomatoid odontogenic hamartoma: what is the better term to denominate this uncommon odontogenic lesion? Oral Dis; 2006 Mar;12(2):200-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid dentinoma or adenomatoid odontogenic hamartoma: what is the better term to denominate this uncommon odontogenic lesion?
  • We report two cases of an uncommon odontogenic lesion, previously described as adenomatoid dentinoma.
  • Odontogenic epithelium formed adenomatoid-like structures, and by scanning electron microscopy a layer of enamel was seen in contact with the dentin.
  • Based on these clinical, radiographic, histological and electron microscopical features we proposed the diagnosis of adenomatoid odontogenic hamartoma.
  • [MeSH-major] Hamartoma / classification. Mandibular Diseases / classification. Mandibular Neoplasms / classification. Odontogenic Tumors / classification. Terminology as Topic

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  • (PMID = 16476044.001).
  • [ISSN] 1354-523X
  • [Journal-full-title] Oral diseases
  • [ISO-abbreviation] Oral Dis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
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44. Batra P, Prasad S, Parkash H: Adenomatoid odontogenic tumour: review and case report. J Can Dent Assoc; 2005 Apr;71(4):250-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumour: review and case report.
  • Adenomatoid odontogenic tumour is a benign (hamartomatous), noninvasive lesion with slow but progressive growth.
  • This report describes a patient with a large adenomatoid odontogenic tumour in the mandible, with the involved mandibular canine being pushed to the contralateral side.
  • The paper also provides a refresher for general dental practitioners about various diagnostic aspects of this tumour and highlights the controversies regarding its origin and management in light of recent findings.
  • [MeSH-major] Mandibular Neoplasms / pathology. Odontogenic Tumors / pathology

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  • (PMID = 15871773.001).
  • [ISSN] 1488-2159
  • [Journal-full-title] Journal (Canadian Dental Association)
  • [ISO-abbreviation] J Can Dent Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Canada
  • [Number-of-references] 29
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45. Reichart PA, Jundt G: [Benign epithelial odontogenic tumors]. Pathologe; 2008 May;29(3):175-6, 178-88

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Benign epithelial odontogenic tumors].
  • [Transliterated title] Benigne epitheliale odontogene Tumoren.
  • The group of benign epithelial odontogenic tumors consists of the four member types of the ameloblastoma family (solid/multicystic, extraosseous/peripheral, desmoplastic, unicystic), squamous odontogenic tumors, calcifying odontogenic tumors, adenomatoid odontogenic tumors, and keratocystic odontogenic tumors, the former "keratocysts" that were recently reclassified by the World Health Organization and are now regarded as tumors.
  • The latter are by far the most frequent tumors in this group, followed by solid/multicystic ameloblastoma.
  • Although the etiology of these lesions is still unknown, a close relationship to normal tooth development is obvious, which is partially imitated by some tumors.
  • [MeSH-major] Jaw Neoplasms / pathology. Odontogenic Cyst, Calcifying / pathology. Odontogenic Tumor, Squamous / pathology. Odontoma / pathology

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  • (PMID = 18389236.001).
  • [ISSN] 1432-1963
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] Adenoameloblastoma
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46. Swasdison S, Dhanuthai K, Jainkittivong A, Philipsen HP: Adenomatoid odontogenic tumors: an analysis of 67 cases in a Thai population. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2008 Feb;105(2):210-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumors: an analysis of 67 cases in a Thai population.
  • OBJECTIVE: The aim of this study was to determine the biologic profile of the adenomatoid odontogenic tumor (AOT) in a Thai population.
  • Age, sex, variants of AOT, site and extent of tumors, associated impacted teeth, initial clinical diagnoses, clinical presentations, and duration of symptoms were analyzed.
  • Adenomatoid odontogenic tumors were observed more often on the left side of jaws (50.7% vs. 38.8%).
  • [MeSH-major] Jaw Neoplasms / epidemiology. Jaw Neoplasms / pathology. Odontogenic Tumors / epidemiology. Odontogenic Tumors / pathology

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  • (PMID = 17613261.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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47. Souza Freitas V, Ferreira de Araújo CR, Alves PM, de Souza LB, Galvão HC, de Almeida Freitas R: Immunohistochemical expression of matrilysins (MMP-7 and MMP-26) in ameloblastomas and adenomatoid odontogenic tumors. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2009 Sep;108(3):417-24

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Immunohistochemical expression of matrilysins (MMP-7 and MMP-26) in ameloblastomas and adenomatoid odontogenic tumors.
  • OBJECTIVE: The aim was to evaluate the expression of matrix metalloproteinases (MMPs) 7 and 26 in ameloblastomas and adenomatoid odontogenic tumors (AOTs).
  • CONCLUSION: The marked expression of these matrilysins suggests their role in the process of tissue remodeling and growth in the studied tumors, but it does not relate to the their distinct patterns of aggressiveness.
  • [MeSH-major] Ameloblastoma / enzymology. Matrix Metalloproteinase 7 / analysis. Matrix Metalloproteinases, Secreted / analysis. Odontogenic Tumors / enzymology
  • [MeSH-minor] Connective Tissue / enzymology. Endothelial Cells / enzymology. Epithelial Cells / enzymology. Epithelium / enzymology. Fibroblasts / enzymology. Humans. Immunohistochemistry

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  • (PMID = 19570695.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] EC 3.4.24.- / MMP26 protein, human; EC 3.4.24.- / Matrix Metalloproteinases, Secreted; EC 3.4.24.23 / MMP7 protein, human; EC 3.4.24.23 / Matrix Metalloproteinase 7
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48. Friedrich RE, Zustin J, Scheuer HA: Adenomatoid odontogenic tumour of the mandible. Anticancer Res; 2010 May;30(5):1787-92

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumour of the mandible.
  • Adenomatoid odontogenic tumour (AOT) is a benign tumour of odontogenic origin.
  • The 23-year old male patient presented in this case study was referred to the maxillofacial surgery clinic due to the incidental radiological finding of a large osteolytic lesion of the anterior mandible with a retained permanent canine at the base of the bone.
  • Some areas of the tumour were alpha-smooth-muscle-actin positive, indicating a myoepithelial differentiation.
  • Differential diagnosis of AOT to other odontogenic tumours, such as ameloblastoma, is crucial for therapy.
  • [MeSH-major] Mandibular Neoplasms / diagnosis. Odontogenic Tumors / diagnosis

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  • (PMID = 20592380.001).
  • [ISSN] 1791-7530
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Actins; 68238-35-7 / Keratins
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49. Kallel R, Ayadi L, Gouiaa N, Chaabouni S, Karray F, Daoud E, Chaari C, Khabir A, Makni S, Boudawara T: [Extrafollicular adenomatoid odontogenic tumour: report of two cases]. Rev Med Brux; 2009 Sep-Oct;30(5):511-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Extrafollicular adenomatoid odontogenic tumour: report of two cases].
  • [Transliterated title] Tumeur odontogène adénomatoïde extrafolliculaire: à propos de deux cas.
  • The purpose of this study was to analysis the clinicopathological features of adenomatoid odontogenic tumour extrafollicular and to discuss the diagnosis pitfull.
  • An exploratory surgical approach was chosen and the final diagnosis was microscopically confirmed to be an extrafollicular variant of adenomatoid odontogenic tumour.
  • The two cases described illustrate clinical and radiographic features of the extrafollicular variant of adenomatoid odontogenic tumour.
  • [MeSH-major] Mandibular Neoplasms / radiography. Odontogenic Tumors / radiography

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  • (PMID = 19998797.001).
  • [ISSN] 0035-3639
  • [Journal-full-title] Revue médicale de Bruxelles
  • [ISO-abbreviation] Rev Med Brux
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Belgium
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50. Farah-Klibi F, Ferchichi L, Beyâa Rassou H, Zairi I, Rameh S, Adouani A, Ben Jilani SB, Zermani R: [Adenomatoid odontogenic tumor: two cases]. Rev Stomatol Chir Maxillofac; 2007 Feb;108(1):61-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Adenomatoid odontogenic tumor: two cases].
  • [Transliterated title] La tumeur odontogénique adénomatoïde: deux cas.
  • INTRODUCTION: Adenomatoid odontogenic tumor, initially referred to as adenoameloblastoma, is a rare and benign odontogenic tumor.
  • CASE REPORTS: We report two cases of adenomatoid odontogenic tumor, which illustrate the radiological and anatomic features of this tumor.
  • DISCUSSION: The clinical, radiological and histological features of adenomatoid odontogenic tumor are distinct from those of ameloblastoma.
  • This tumor is frequently misdiagnosed as other odontogenic cysts or tumors.
  • We discuss the anatomoclinical features and the histogenesis of this rare tumor.
  • [MeSH-major] Mandibular Neoplasms / pathology. Maxillary Neoplasms / pathology. Odontogenic Tumors / pathology

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  • (PMID = 17275864.001).
  • [ISSN] 0035-1768
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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51. Cudney N, Persico J, Cordell KG, D'Silva NJ: Adenomatoid odontogenic tumor developing in association with an odontoma: report of a case. Quintessence Int; 2008 Sep;39(8):693-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumor developing in association with an odontoma: report of a case.
  • The adenomatoid odontogenic tumor is an unusual lesion that usually presents in the anterior maxilla.
  • In contrast, the odontoma is the most common odontogenic tumor.
  • The concurrent occurrence of these tumors in a single lesion is extremely rare.
  • Such a lesion occurred in the mandibular canine region of a 13-year-old boy.
  • The histopathologic findings were consistent with concurrent occurrence of an odontoma and adenomatoid odontogenic tumor.
  • [MeSH-major] Mandibular Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Odontogenic Tumors / pathology

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  • (PMID = 19107257.001).
  • [ISSN] 1936-7163
  • [Journal-full-title] Quintessence international (Berlin, Germany : 1985)
  • [ISO-abbreviation] Quintessence Int
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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52. Friedrich RE, Scheuer HA, Zustin J: Adenomatoid odontogenic tumor (AOT) of maxillary sinus: case report with respect to immunohistochemical findings. In Vivo; 2009 Jan-Feb;23(1):111-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumor (AOT) of maxillary sinus: case report with respect to immunohistochemical findings.
  • This report describes the surgical therapy, clinical course and morphological characteristics of an adenomatoid odontogenic tumor that developed in the maxilla of a 16-year-old patient.
  • The cystic tumor filled the maxillary sinus and was removed with the retained tooth.
  • The tumor showed immunoreactivity for certain types of cytokeratins, vimentin and p63, and was focally immunoreactive for alpha smooth muscle actin and epithelial membrane antigen.
  • [MeSH-major] Maxillary Sinus / pathology. Maxillary Sinus Neoplasms / pathology. Odontogenic Tumors / pathology
  • [MeSH-minor] Adolescent. Biomarkers, Tumor / metabolism. Humans. Male. Treatment Outcome

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  • (PMID = 19368134.001).
  • [ISSN] 0258-851X
  • [Journal-full-title] In vivo (Athens, Greece)
  • [ISO-abbreviation] In Vivo
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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53. Bravo M, White D, Miles L, Cotton R: Adenomatoid odontogenic tumor mimicking a dentigerous cyst. Int J Pediatr Otorhinolaryngol; 2005 Dec;69(12):1685-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumor mimicking a dentigerous cyst.
  • Adenomatoid odontogenic tumor (AOT) is a slow-growing, asymptomatic and uncommon lesion that arises from odontogenic epithelium with inductive effects on connective tissue.
  • Histopathologic examination demonstrates cuboidal or spindle-shaped epithelial cells forming aggregates or rosette-like structures with minimal connective tissue, and cuboidal or low columnar cells forming glandular duct-like structures.
  • [MeSH-major] Dentigerous Cyst / diagnosis. Maxillary Diseases / diagnosis. Maxillary Neoplasms / diagnosis. Odontogenic Tumors / diagnosis. Tooth, Unerupted

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  • (PMID = 15996761.001).
  • [ISSN] 0165-5876
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ireland
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54. Kayser K, Kosjerina Z, Goldmann T, Kayser G, Kazmierczak B, Vollmer E: Lung carcinoma-associated atypical adenomatoid hyperplasia, squamous cell dysplasia, and chromosome alterations in non-neoplastic bronchial mucosa. Lung Cancer; 2005 Feb;47(2):205-14
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lung carcinoma-associated atypical adenomatoid hyperplasia, squamous cell dysplasia, and chromosome alterations in non-neoplastic bronchial mucosa.
  • The frequency of phenotype preneoplastic lesions (atypical adenomatoid hyperplasia (AAH) and squamous cell dysplasia (SCD)) was analyzed at distinct distances from the tumor boundary in 150 lung carcinomas.
  • The degree of cellular atypia decreased with increasing distance from tumor boundary in both AAH and SCD.
  • At similar distances, genotype (chromosome) alterations of surrounding bronchial mucosa were studied in additional 55 primary and secondary lung tumors by karyotype analysis.
  • Losses of y chromosome were seen in both malignancy and adjacent bronchial mucosa, and interpreted as "tumor related", losses of chromosome 21 in adjacent bronchial mucosa were non-tumor related in adenocarcinoma and metastases, losses of chromosome 19 in adjacent bronchial mucosa occurred independently in squamous cell and large cell carcinomas.
  • The data suggest the hypothesis that preneoplastic lesions in the lung might be partly induced by the tumor itself.

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  • (PMID = 15639719.001).
  • [ISSN] 0169-5002
  • [Journal-full-title] Lung cancer (Amsterdam, Netherlands)
  • [ISO-abbreviation] Lung Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
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55. Vera Sempere FJ, Artes Martínez MJ, Vera Sirera B, Bonet Marco J: Follicular adenomatoid odontogenic tumor: immunohistochemical study. Med Oral Patol Oral Cir Bucal; 2006 Jul;11(4):E305-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Follicular adenomatoid odontogenic tumor: immunohistochemical study.
  • Adenomatoid odontogenic tumor (AOT) is an uncommon benign odontogenic lesion that affects young patients, with female predominance, mainly in second decade, showing a radiolucent unilocular image associated with an unerupted tooth, usually a canine.
  • In spite of previous and confusing denominations, such as adenoameloblastoma or adenomatoid ameloblastic tumor, AOT is a benign tumor with a very low rate of recurrence, that show a peculiar morphological picture (basaloid appearance with glandular-like structures, calcifying areas, and amiloid-like material) that allow its histopathological recognition.
  • We present a clinicopathological analysis of a case of follicular AOT affecting the mandible in a 9 years-old female patient associated with unerupted lower left canine.
  • According to its benign character and low potential for recurrence, AOT revealed a scant proliferative activity (2-3% nuclei showed Ki-67 positivity) limited to some epithelial nodules (AE1-3 +) of fusiform appearance.
  • [MeSH-major] Mandibular Neoplasms / pathology. Odontogenic Tumors / pathology

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  • (PMID = 16816813.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng; spa
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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56. Roffman E, Baredes S, Mirani N: Respiratory epithelial adenomatoid hamartomas and chondroosseous respiratory epithelial hamartomas of the sinonasal tract: a case series and literature review. Am J Rhinol; 2006 Nov-Dec;20(6):586-90

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Respiratory epithelial adenomatoid hamartomas and chondroosseous respiratory epithelial hamartomas of the sinonasal tract: a case series and literature review.
  • BACKGROUND: Respiratory epithelial adenomatoid hamartomas (REAH) and chondroosseous respiratory epithelial (CORE) hamartomas are rare sinonasal/nasopharyngeal lesions first characterized in 1995.
  • Although REAH and CORE hamartomas are benign, nonneoplastic lesions, awareness and recognition of these lesions are important because they can be confused grossly and microscopically with more threatening sinonasal tumors.
  • METHODS: This report presents two cases of REAH and one case of a CORE hamartoma.

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  • (PMID = 17181098.001).
  • [ISSN] 1050-6586
  • [Journal-full-title] American journal of rhinology
  • [ISO-abbreviation] Am J Rhinol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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57. de Medeiros AM, Nonaka CF, Galvão HC, de Souza LB, Freitas Rde A: Expression of extracellular matrix proteins in ameloblastomas and adenomatoid odontogenic tumors. Eur Arch Otorhinolaryngol; 2010 Feb;267(2):303-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of extracellular matrix proteins in ameloblastomas and adenomatoid odontogenic tumors.
  • This study evaluated the expression of fibronectin, tenascin and type I collagen in ameloblastomas and adenomatoid odontogenic tumors (AOTs) aiming to contribute with the comprehension of the differences in the biological behavior of these tumors.
  • All tumors presented moderate fibronectin expression in the stroma.
  • Solid ameloblastomas showed intense expression of fibronectin at the epithelial-mesenchymal interface, whereas desmoplastic ameloblastomas revealed no immunoexpression of fibronectin at this site.
  • Ameloblastomas presented stronger immunoreactivity to tenascin than AOTs, especially at the epithelial-mesenchymal interface.
  • [MeSH-major] Adenomatoid Tumor / metabolism. Ameloblastoma / metabolism. Collagen Type I / biosynthesis. Fibronectins / biosynthesis. Jaw Neoplasms / metabolism. Odontogenic Tumors / metabolism. Tenascin / biosynthesis
  • [MeSH-minor] Biomarkers, Tumor / biosynthesis. Extracellular Matrix Proteins / biosynthesis. Humans. Immunohistochemistry. Prognosis

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  • [Cites] Int J Biochem Cell Biol. 2004 Jun;36(6):986-90 [15094113.001]
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  • (PMID = 19466441.001).
  • [ISSN] 1434-4726
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Collagen Type I; 0 / Extracellular Matrix Proteins; 0 / Fibronectins; 0 / Tenascin
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58. Nigam S, Gupta SK, Chaturvedi KU: Adenomatoid odontogenic tumor--a rare cause of jaw swelling. Braz Dent J; 2005;16(3):251-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumor--a rare cause of jaw swelling.
  • Adenomatoid odontogenic tumor (AOT) is an uncommon tumor of odontogenic origin, characterized histologically by the formation of ductlike structures with amyloid-like deposits.
  • Histogenesis of AOT is still uncertain and it is often considered as a hamartomatous lesion rather than a true neoplasm.
  • AOT has a benign behavior and conservative surgical enucleation or curettage is sufficient.
  • [MeSH-major] Maxillary Neoplasms / diagnosis. Odontogenic Tumors / diagnosis

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  • (PMID = 16429194.001).
  • [ISSN] 1806-4760
  • [Journal-full-title] Brazilian dental journal
  • [ISO-abbreviation] Braz Dent J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Brazil
  • [Number-of-references] 8
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59. Nonaka CF, de Souza LB, Quinderé LB: Adenomatoid odontogenic tumour associated with dentigerous cyst--unusual case report. Braz J Otorhinolaryngol; 2007 Jan-Feb;73(1):129-31

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumour associated with dentigerous cyst--unusual case report.
  • The adenomatoid odontogenic tumor is a relatively uncommon lesion which mainly affects females in their second decade of life, exhibiting predilection for the anterior region of the maxilla.
  • In this paper we present a case of adenomatoid odontogenic tumor associated with a dentigerous cyst affecting the left maxillary region in a 13-year-old female.
  • [MeSH-major] Dentigerous Cyst / pathology. Maxillary Neoplasms / pathology. Odontogenic Tumors / pathology

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  • (PMID = 17505612.001).
  • [ISSN] 1808-8694
  • [Journal-full-title] Brazilian journal of otorhinolaryngology
  • [ISO-abbreviation] Braz J Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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60. Jivan V, Altini M, Meer S: Secretory cells in adenomatoid odontogenic tumour: tissue induction or metaplastic mineralisation? Oral Dis; 2008 Jul;14(5):445-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Secretory cells in adenomatoid odontogenic tumour: tissue induction or metaplastic mineralisation?
  • OBJECTIVE: To undertake a detailed histological investigation of a large series of adenomatoid odontogenic tumours (AOT) to document the frequency and histomorphology of secretory cells which might indicate an inductive capacity.
  • [MeSH-major] Adenoma / pathology. Calcinosis / metabolism. Dental Enamel Proteins / metabolism. Odontogenic Tumors / pathology. Secretory Vesicles / metabolism

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  • (PMID = 18938270.001).
  • [ISSN] 1354-523X
  • [Journal-full-title] Oral diseases
  • [ISO-abbreviation] Oral Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Dental Enamel Proteins
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61. Bartake AR, Punnya VA, Sudeendra P, Rekha K: Two adenomatoid odontogenic tumours of the maxilla: a case report. Br J Oral Maxillofac Surg; 2009 Dec;47(8):638-40

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Two adenomatoid odontogenic tumours of the maxilla: a case report.
  • An adenomatoid odontogenic tumour (AOT) is a well-recognised benign tumour that enlarges slowly.
  • We report here the rare occurrence of two separate tumours in the anterior maxillary region that have not been documented previously.
  • [MeSH-major] Maxillary Neoplasms / diagnosis. Neoplasms, Multiple Primary / diagnosis. Odontogenic Tumors / diagnosis

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  • (PMID = 19131147.001).
  • [ISSN] 1532-1940
  • [Journal-full-title] The British journal of oral & maxillofacial surgery
  • [ISO-abbreviation] Br J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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62. Philipsen HP, Reichart PA, Siar CH, Ng KH, Lau SH, Zhang X, Dhanuthai K, Swasdison S, Jainkittivong A, Meer S, Jivan V, Altini M, Hazarey V, Ogawa I, Takata T, Taylor AA, Godoy H, Delgado WA, Carlos-Bregni R, Macias JF, Matsuzaka K, Sato D, Vargas PA, Adebayo ET: An updated clinical and epidemiological profile of the adenomatoid odontogenic tumour: a collaborative retrospective study. J Oral Pathol Med; 2007 Aug;36(7):383-93

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An updated clinical and epidemiological profile of the adenomatoid odontogenic tumour: a collaborative retrospective study.
  • BACKGROUND: Adenomatoid odontogenic tumour (AOT) is a benign odontogenic jaw lesion.
  • RESULTS: 550 new cases were retrieved, and of a total of 1082 cases analysed, 87.2% were found in the second and third decades.
  • The M:F ratio was 1:1.9.
  • CONCLUSIONS: This updated review based on the largest number of AOT cases ever presented, confirms the distinctive, although not pathognomonic clinicopathological profile of the AOT, its worldwide occurrence, and its consistently benign behaviour.
  • [MeSH-major] Jaw Neoplasms / epidemiology. Odontogenic Tumors / epidemiology

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  • (PMID = 17617830.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] Denmark
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63. Fitzhugh VA, Mirani N: Respiratory epithelial adenomatoid hamartoma: a review. Head Neck Pathol; 2008 Sep;2(3):203-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Respiratory epithelial adenomatoid hamartoma: a review.
  • Respiratory epithelial adenomatoid hamartoma (REAH) is an uncommon lesion of the upper aerodigestive tract first described by Wenig and Heffner in 1995 as prominent glandular proliferations lined by ciliated respiratory epithelium originating from the surface epithelium.
  • While REAH is benign, awareness and recognition of the lesion is important because it can be easily confused grossly and microscopically with more threatening tumors such as inverted papilloma and sinonasal carcinoma.
  • [MeSH-minor] Biomarkers / metabolism. Epithelial Cells / metabolism. Epithelial Cells / pathology. Female. Humans. Loss of Heterozygosity. Male

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  • [Cites] J Laryngol Otol. 2002 Apr;116(4):317-8 [11945202.001]
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  • (PMID = 20614315.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers
  • [Other-IDs] NLM/ PMC2807563
  • [Keywords] NOTNLM ; Inverted papilloma / Nasopharynx / Respiratory epithelial adenomatoid hamartoma / Sinonasal adenocarcinoma / Upper aerodigestive tract
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64. Argeitis J, Botsis D, Kairi-Vassilatou E, Hasiakos D, Papakonstantinou K, Kondi-Pafiti A: Congenital cystic adenomatoid lung malformation: report of two cases and literature review. Clin Exp Obstet Gynecol; 2008;35(1):76-80

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Congenital cystic adenomatoid lung malformation: report of two cases and literature review.
  • Congenital cystic adenomatoid malformations of the fetal lung (CCAM) are rare embryonic developmental abnormalities.
  • They are considered as benign hamartomatous or dysplastic lung tumors characterized by overgrowth of the terminal respiratory bronchioles at the expense of the saccular spaces.
  • Two cases of congenital cystic adenomatoid malformation of the fetal lung diagnosed in our institution during the last four years are reported.
  • [MeSH-major] Cystic Adenomatoid Malformation of Lung, Congenital / pathology. Cystic Adenomatoid Malformation of Lung, Congenital / ultrasonography. Ultrasonography, Prenatal

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  • (PMID = 18390089.001).
  • [ISSN] 0390-6663
  • [Journal-full-title] Clinical and experimental obstetrics & gynecology
  • [ISO-abbreviation] Clin Exp Obstet Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 11
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65. de Souza Andrade ES, Miguel MC, de Almeida Freitas R, Pereira Pinto L, Batista de Souza L: Immunoexpression of integrins in ameloblastoma, adenomatoid odontogenic tumor, and human tooth germs. Int J Surg Pathol; 2008 Jul;16(3):277-85

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Immunoexpression of integrins in ameloblastoma, adenomatoid odontogenic tumor, and human tooth germs.
  • The expression of integrins alpha2beta1, alpha3beta1, and alpha5beta1 in 30 ameloblastomas (20 solid and 10 unicystic tumors), 12 adenomatoid odontogenic tumors (AOTs), and 5 human tooth germs in different stages of odontogenesis was analyzed.
  • The lack of detection of integrin alpha3beta1 in tooth germs and its detection in the odontogenic tumors studied suggest that this integrin might be used as a marker of neoplastic transformation in odontogenic tissues.
  • [MeSH-major] Ameloblastoma / metabolism. Biomarkers, Tumor / metabolism. Jaw Neoplasms / metabolism. Receptors, Collagen / metabolism. Tooth Germ / metabolism

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  • (PMID = 18573784.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Integrin alpha2beta1; 0 / Integrin alpha3beta1; 0 / Integrin alpha5beta1; 0 / Receptors, Collagen
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66. Chuan-Xiang Z, Yan G: Adenomatoid odontogenic tumor: a report of a rare case with recurrence. J Oral Pathol Med; 2007 Aug;36(7):440-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumor: a report of a rare case with recurrence.
  • Adenomatoid odontogenic tumor (AOT) is an uncommon tumor of odontogenic origin, composed of odontogenic epithelium in a variety of histoarchitectural patterns, and characterized by slow but progressive growth.
  • The tumor was diagnosed as AOT with well-defined unilocular radiolucency shown in X-ray graphs and solid nodule of cuboidal or columnar cells of odontogenic epithelium forming typical nests or rosette-like structures as well as characteristic duct-like spaces in histologic findings.
  • [MeSH-major] Maxillary Neoplasms / pathology. Neoplasm Recurrence, Local / pathology. Odontogenic Tumors / pathology

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  • (PMID = 17617839.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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67. Kumamoto H, Ooya K: Expression of bone morphogenetic proteins and their associated molecules in ameloblastomas and adenomatoid odontogenic tumors. Oral Dis; 2006 Mar;12(2):163-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of bone morphogenetic proteins and their associated molecules in ameloblastomas and adenomatoid odontogenic tumors.
  • OBJECTIVE: To further clarify the roles of regulators of embryonic development, bone morphogenetic protein (BMPs) and their associated molecules, in oncogenesis and cytodifferentiation of odontogenic tumors, the expression of these regulator molecules were analyzed in epithelial odontogenic tumors as well as in tooth germs.
  • MATERIALS AND METHODS: Tooth germs, ameloblastomas, adenomatoid odontogenic tumors, and malignant ameloblastomas were examined by RT-PCR and immunohistochemistry for detection of BMP-2, -4, -7, BMP receptors I and II (BMPR-I, BMPR-II), core-binding factor alpha1 (CBFA1), and osterix.
  • Immunohistochemical reactivity for BMPs, BMPRs, and CBFA1 was detected in both epithelial and mesenchymal cells of tooth germs and epithelial odontogenic tumors.
  • BMPs and BMPRs were evidently expressed in odontogenic epithelial cells in tooth germs and epithelial odontogenic tumors.
  • Nuclear CBFA1 expression was detected scatteredly in odontogenic epithelial cells in normal and neoplastic odontogenic tissues, as well as in some mesenchymal cells in tooth germs and in some stromal cells in epithelial odontogenic tumors.
  • CONCLUSION: BMPs and their associated molecules might play a role in cytodifferentiation of normal and neoplastic odontogenic epithelium via epithelial-mesenchymal interactions.
  • [MeSH-major] Ameloblastoma / pathology. Bone Morphogenetic Proteins / analysis. Odontogenic Tumors / pathology
  • [MeSH-minor] Bone Morphogenetic Protein 2. Bone Morphogenetic Protein 4. Bone Morphogenetic Protein 7. Bone Morphogenetic Protein Receptors, Type I / analysis. Bone Morphogenetic Protein Receptors, Type II / analysis. Cell Differentiation. Cell Nucleus / ultrastructure. Cell Transformation, Neoplastic / pathology. Core Binding Factor Alpha 1 Subunit / analysis. Epithelial Cells / pathology. Epithelium / pathology. Humans. Immunohistochemistry. Mesoderm / pathology. Reverse Transcriptase Polymerase Chain Reaction. Stromal Cells / pathology. Tooth Germ / pathology. Transcription Factors / analysis. Transforming Growth Factor beta / analysis

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  • (PMID = 16476038.001).
  • [ISSN] 1354-523X
  • [Journal-full-title] Oral diseases
  • [ISO-abbreviation] Oral Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / BMP2 protein, human; 0 / BMP4 protein, human; 0 / BMP7 protein, human; 0 / Bone Morphogenetic Protein 2; 0 / Bone Morphogenetic Protein 4; 0 / Bone Morphogenetic Protein 7; 0 / Bone Morphogenetic Proteins; 0 / Core Binding Factor Alpha 1 Subunit; 0 / Sp7 protein, human; 0 / Transcription Factors; 0 / Transforming Growth Factor beta; EC 2.7.11.30 / Bone Morphogenetic Protein Receptors, Type I; EC 2.7.11.30 / Bone Morphogenetic Protein Receptors, Type II
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68. Motamedi MH, Shafeie HA, Azizi T: Salvage of an impacted canine associated with an adenomatoid odontogenic tumour: a case report. Br Dent J; 2005 Jul 23;199(2):89-90

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Salvage of an impacted canine associated with an adenomatoid odontogenic tumour: a case report.
  • The adenomatoid odontogenic tumour (AOT) has been known by a number of descriptive names (adenoameloblastoma, ameloblastic adenomatoid tumour, glandular ameloblastoma, and adenomatoid ameloblastoma) since it was first reported and later recognised as a distinct odontogenic lesion unrelated to ameloblastoma.
  • Although it was considered to be a variant of ameloblastoma at one time leading surgeons to perform unduly aggressive surgery, the treatment outcome experience has borne out the benign, nonaggressive nature of this lesion.
  • The AOT is now considered to be a hamartoma with completely benign behaviour.
  • Thus, it appears needless to extract involved anterior teeth associated with the tumour, especially in children.
  • We have not found such a procedure to have been done for this tumour in the literature.
  • [MeSH-major] Cuspid / pathology. Mandibular Neoplasms / complications. Odontogenic Tumors / complications. Tooth Movement / methods. Tooth, Impacted / etiology

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  • (PMID = 16041334.001).
  • [ISSN] 0007-0610
  • [Journal-full-title] British dental journal
  • [ISO-abbreviation] Br Dent J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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69. Santos JN, Lima FO, Romério P, Souza VF: Adenomatoid odontogenic tumor: an unusual case exhibiting cribriform aspect. Quintessence Int; 2008 Oct;39(9):777-81

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumor: an unusual case exhibiting cribriform aspect.
  • The occurrence of areas exhibiting cribriform morphology in odontogenic tumors is not a very frequent finding.
  • This report describes the case of a 22-year-old man who presented with swelling in the left anterior maxilla.
  • Histopathologically, the lesion consisted of a cystic wall exhibiting an odontogenic epithelium lining composed of oval, angular, and elongated cells forming a cribriform pattern.
  • [MeSH-major] Maxillary Neoplasms / pathology. Odontogenic Tumors / pathology

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  • (PMID = 19093052.001).
  • [ISSN] 1936-7163
  • [Journal-full-title] Quintessence international (Berlin, Germany : 1985)
  • [ISO-abbreviation] Quintessence Int
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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70. El-Daly H, Rao P, Palazzo F, Gudi M: A rare entity of an unusual site: adenomatoid tumour of the adrenal gland: a case report and review of the literature. Patholog Res Int; 2010;2010:702472
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A rare entity of an unusual site: adenomatoid tumour of the adrenal gland: a case report and review of the literature.
  • This is a case report of a 51 year old male who was found to have an incidental left sided non-functioning adrenal mass on routine medical examination and which was confirmed by CT and MRI scans.
  • On gross examination the tumour was a solitary well circumscribed solid-cystic mass with a homogenous pinkish white cut surface.
  • On microscopic examination, the tumour was composed of variably sized tubules and fenestrated channels lined by bland cuboidal cells to epithelioid cells.
  • Immunohistochemically the tumour cells stained with calretinin, Cam5.2, CK7, vimentin and focally with EMA.
  • A diagnosis of an adenomatoid tumour as made.
  • Adenomatoid tumours are rare benign tumours of mesothelial derivation.
  • The adrenal gland is devoid of a mesothelial lining and the most accepted hypothesis for an adenomatoid tumour originating in the adrenal gland is derivation from mesothelial rests.
  • As the adrenal gland is an extremely rare site of occurrence for an adenomatoid tumour, it is frequently mistaken for adrenocortical tumours or a pheochromocytoma clinically and radiologically.

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  • (PMID = 21151721.001).
  • [ISSN] 2042-003X
  • [Journal-full-title] Pathology research international
  • [ISO-abbreviation] Patholog Res Int
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2990199
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71. Gadewar DR, Srikant N: Adenomatoid odontogenic tumour: tumour or a cyst, a histopathological support for the controversy. Int J Pediatr Otorhinolaryngol; 2010 Apr;74(4):333-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumour: tumour or a cyst, a histopathological support for the controversy.
  • Adenomatoid odontogenic tumour (AOT) is a well-established odontogenic tumour with various clinicopathological variants.
  • [MeSH-major] Adenomatoid Tumor / pathology. Maxillary Neoplasms / pathology. Odontogenic Tumors / pathology

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  • [CommentIn] Int J Pediatr Otorhinolaryngol. 2010 Jul;74(7):836-7; author reply 837 [20413165.001]
  • (PMID = 20079941.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Ireland
  • [Number-of-references] 34
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72. de Macedo LG, de Macedo NL, do Socorro Ferreira Monteiro A: Fresh-frozen human bone graft for repair of defect after adenomatoid odontogenic tumour removal. Cell Tissue Bank; 2009 Aug;10(3):221-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fresh-frozen human bone graft for repair of defect after adenomatoid odontogenic tumour removal.
  • The aim of this paper was report the clinical, radiographic, and histological case of adenomatoid odontogenic tumour (AOT) in adolescent woman as well as present the reconstructive treatment of AOT using fresh-frozen human bone graft with guided bone regeneration.
  • AOT is a benign, noninvasive lesion with slow but progressive growth.
  • [MeSH-major] Adenomatoid Tumor / surgery. Bone Regeneration / physiology. Bone Transplantation. Guided Tissue Regeneration, Periodontal. Odontogenic Tumors / surgery

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  • (PMID = 19132551.001).
  • [ISSN] 1573-6814
  • [Journal-full-title] Cell and tissue banking
  • [ISO-abbreviation] Cell Tissue Bank
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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73. Jivan V, Altini M, Meer S, Mahomed F: Adenomatoid odontogenic tumor (AOT) originating in a unicystic ameloblastoma: a case report. Head Neck Pathol; 2007 Dec;1(2):146-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumor (AOT) originating in a unicystic ameloblastoma: a case report.
  • The follicular variant of the adenomatoid odontogenic tumor (AOT) is thought to originate from the reduced enamel epithelium of the dental follicle.
  • This paper presents a case of an extra-follicular AOT, which we believe originated from the epithelial lining of a unicystic ameloblastoma, and reviews the literature.
  • The available evidence seems to indicate that some extra-follicular AOTs might arise as secondary phenomena within pre-existing odontogenic cysts or cystic tumors.
  • [MeSH-major] Adenomatoid Tumor / pathology. Ameloblastoma / pathology. Jaw Neoplasms / pathology. Odontogenic Tumors / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / metabolism. Calbindin 2. Humans. Male. Neoplasms, Multiple Primary. S100 Calcium Binding Protein G / metabolism

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  • [Cites] Oral Dis. 2003 Jan;9(1):1-6 [12617250.001]
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  • (PMID = 20614266.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Calbindin 2; 0 / S100 Calcium Binding Protein G
  • [Other-IDs] NLM/ PMC2807512
  • [Keywords] NOTNLM ; Adenomatoid odontogenic tumor / Extra-follicular / Unicystic ameloblastoma
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74. Garg D, Palaskar S, Shetty VP, Bhushan A: Adenomatoid odontogenic tumor - hamartoma or true neoplasm: a case report. J Oral Sci; 2009 Mar;51(1):155-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumor - hamartoma or true neoplasm: a case report.
  • Adenomatoid odontogenic tumor (AOT) is an uncommon tumor of odontogenic origin with a relative frequency of 2.2 - 7.1%.
  • As the histogenesis of AOT is still uncertain, it is sometimes categorized as a hamartomatous lesion rather than a true neoplasm.
  • The tumor showed some unusual and aggressive features that suggested it was a true neoplasm.
  • [MeSH-major] Hamartoma / diagnosis. Maxillary Diseases / diagnosis. Maxillary Neoplasms / diagnosis. Odontogenic Tumors / diagnosis

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  • (PMID = 19325215.001).
  • [ISSN] 1343-4934
  • [Journal-full-title] Journal of oral science
  • [ISO-abbreviation] J Oral Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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75. Ladeinde AL, Ajayi OF, Ogunlewe MO, Adeyemo WL, Arotiba GT, Bamgbose BO, Akinwande JA: Odontogenic tumors: a review of 319 cases in a Nigerian teaching hospital. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2005 Feb;99(2):191-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Odontogenic tumors: a review of 319 cases in a Nigerian teaching hospital.
  • OBJECTIVE: This study sought to determine the relative frequency of odontogenic tumors in a Nigerian population and to compare these data with previous reports.
  • STUDY DESIGN: Records of patients seen at the Lagos University Teaching Hospital between January 1980 and December 2003, with histologic diagnosis of odontogenic tumors (based on World Health Organisation classification, 1992), were analyzed.
  • RESULTS: Odontogenic tumors constituted 9.6% of all the biopsies of oral and jaw lesions seen within the period under study.
  • Among these cases, 96.6% of the tumors were benign and 3.4% were malignant.
  • Ameloblastoma with predilection for the mandible was the most frequent odontogenic tumor (63%), followed by adenomatoid odontogenic tumor (AOT) (7.5%), myxoma (6.5%), calcifying epithelial odontogenic cyst (5.3%), and odontogenic fibroma (5.3%).
  • More cases of malignant odontogenic tumors were seen than cases of calcifying epithelial odontogenic tumor and odontomas.
  • No significant difference was found between the mean ages of patients with benign odontogenic tumors and those with malignant odontogenic tumors ( P=.058).
  • CONCLUSIONS: Odontogenic tumors, especially ameloblastoma, are not considered rare among Nigerians, whereas odontoma, regarded as the most frequent odontogenic tumor in North and South America, is rare.
  • [MeSH-major] Odontogenic Tumors / epidemiology

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  • (PMID = 15660091.001).
  • [ISSN] 1079-2104
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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76. Takeda M, Kasai T, Enomoto Y, Takano M, Morita K, Kadota E, Nonomura A: 9p21 deletion in the diagnosis of malignant mesothelioma, using fluorescence in situ hybridization analysis. Pathol Int; 2010 May;60(5):395-9
MedlinePlus Health Information. consumer health - Mesothelioma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] 9p21 deletion in the diagnosis of malignant mesothelioma, using fluorescence in situ hybridization analysis.
  • Homozygous deletion of 9p21, the locus harboring the p16 gene, has been reported as one of the most common genetic alterations in malignant mesotheliomas (MMs).
  • Previous studies showed that this alteration might be useful for differentiating benign from malignant mesothelial tumors in cytology and surgical specimens.
  • The purpose of this study is to evaluate the diagnostic utility of 9p21 homozygous deletion assessed by FISH in mesothelial neoplasm and hyperplasia of Japanese patients using paraffin-embedded tissue.
  • In contrast, no cases of adenomatoid tumor, benign mesothelial multicystic tumor, reactive mesothelial hyperplasia or pleuritis showed 9p21 deletion (P < 0.005).
  • 9p21 homozygous deletion correlated well with p16 protein expression in the tumor cells.
  • Our study suggests that 9p21 homozygous deletion assessed by FISH on paraffin-embedded tissue may be very useful for differentiating MM from reactive mesothelial proliferation.
  • [MeSH-major] Chromosomes, Human, Pair 9. Genes, p16. Heart Neoplasms / diagnosis. In Situ Hybridization, Fluorescence / methods. Mesothelioma / diagnosis. Peritoneal Neoplasms / diagnosis. Pleural Neoplasms / diagnosis
  • [MeSH-minor] Biomarkers, Tumor / genetics. Biomarkers, Tumor / metabolism. DNA, Neoplasm / analysis. Epithelium / pathology. Female. Gene Deletion. Gene Dosage. Humans. Pericardium / metabolism. Pericardium / pathology

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  • (PMID = 20518890.001).
  • [ISSN] 1440-1827
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Neoplasm
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77. Tsolakis AV, Stridsberg M, Grimelius L, Portela-Gomes GM, Falkmer SE, Waldum HL, Janson ET: Ghrelin immunoreactive cells in gastric endocrine tumors and their relation to plasma ghrelin concentration. J Clin Gastroenterol; 2008 Apr;42(4):381-8
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ghrelin immunoreactive cells in gastric endocrine tumors and their relation to plasma ghrelin concentration.
  • GOALS: Our aim was to elucidate the incidence and distribution pattern of ghrelin-immunoreactive (IR) cells in various types of human gastric endocrine tumors, and their surrounding mucosa, and relate the findings to total ghrelin concentrations in plasma.
  • STUDY: Forty-eight gastric endocrine tumors were included in the study: 32 type I ECL-CCs, 3 type II, 9 type III, 1 non-ECL-CC, and 3 poorly differentiated endocrine carcinomas.
  • The tumors were analyzed immunohistochemically with antibodies raised versus chromogranin A, synaptophysin, serotonin, somatostatin, vesicular monoamine transporter 2 and ghrelin.
  • RESULTS: Ghrelin-IR cells were found in all types I and II ECL-CCs but in only a few cases of the other tumors.
  • Ghrelin-IR cells were also found among the hyperplastic endocrine cells in the mucosa surrounding types I and II, where they showed diffuse, linear, nodular and adenomatoid hyperplasia patterns.
  • [MeSH-major] Antibodies, Neoplasm / immunology. Carcinoid Tumor / immunology. Gastric Mucosa / pathology. Ghrelin / immunology. Stomach Neoplasms / immunology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biomarkers, Tumor. Female. Humans. Hyperplasia. Immunohistochemistry. Male. Middle Aged. Prognosis. Radioimmunoassay. Severity of Illness Index

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  • (PMID = 18277901.001).
  • [ISSN] 0192-0790
  • [Journal-full-title] Journal of clinical gastroenterology
  • [ISO-abbreviation] J. Clin. Gastroenterol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Neoplasm; 0 / Biomarkers, Tumor; 0 / Ghrelin
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78. Effiom OA, Odukoya O: Adenomatoid odontogenic tumour: a clinico-pathological analysis and melanin pigmentation study of 31 Nigerian cases. Niger Postgrad Med J; 2005 Jun;12(2):131-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumour: a clinico-pathological analysis and melanin pigmentation study of 31 Nigerian cases.
  • AIM: Clinicopathological analysis and melanin pigmentation occurrence in adenomatoid odontogenic tumour (AOT) diagnosed and managed at the Lagos University Teaching Hospital during a 29- year period.
  • RESULTS: AOT is an uncommon type of odontogenic tumour that is commoner in younger age group (8-35 years) with site predilection for the anterior maxilla (64.5%).
  • [MeSH-major] Jaw Neoplasms / pathology. Odontogenic Tumors / pathology. Skin Pigmentation

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  • (PMID = 15997264.001).
  • [ISSN] 1117-1936
  • [Journal-full-title] The Nigerian postgraduate medical journal
  • [ISO-abbreviation] Niger Postgrad Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nigeria
  • [Chemical-registry-number] 0 / Melanins
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79. Young RH: Testicular tumors--some new and a few perennial problems. Arch Pathol Lab Med; 2008 Apr;132(4):548-64
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Testicular tumors--some new and a few perennial problems.
  • The histopathology of testicular tumors is presented, emphasizing new, unusual, or underemphasized aspects.
  • Within the category of seminoma of the usual type, the recent literature has drawn attention to the presence in occasional tumors of solid or hollow tubules or spaces of varying sizes and shape that may result in cribriform or microcystic patterns, causing potential confusion with other neoplasms, most notably Sertoli cell tumor or yolk sac tumor.
  • Although regions of typical neoplasia and awareness of this phenomenon usually will be diagnostic, immunohistochemistry may play a role in excluding Sertoli cell tumor or yolk sac tumor.
  • Although immunohistochemistry can play an undoubted helpful role in this and selected other areas of testicular tumor evaluation, careful evaluation of the gross and routine microscopic features will solve the vast majority of diagnostic problems.
  • Spermatocytic seminoma remains a crucial pitfall in diagnosis, and the pathologist must always be alert to the possible diagnosis when looking at a seminomatous neoplasm, particularly in an older patient, although about one third of these tumors occur in the usual seminoma age range.
  • The enigmatic and picturesque tumor, polyembryoma, which virtually never occurs in pure form but may be a confusing component of a variety of mixed germ cell tumors, is discussed and illustrated.
  • Within the sex cord-stromal family of neoplasms, recent contributions and elaborations of unusual morphologic features of Leydig cell tumors and Sertoli cell tumors are presented.
  • The peculiar lesion, intratubular large cell hyalinizing Sertoli cell tumor, of young boys with Peutz-Jeghers syndrome, is briefly discussed.
  • Although secondary tumors to the testis have not received the same attention in the literature as the similar phenomenon in the female gonad, remarkable examples of testicular spread of diverse neoplasms, usually carcinoma but rarely melanoma, are seen, and the pathologist should be alert to this possibility, particularly when examining an unusual morphology in an older patient.
  • Finally, a few comments are made on the common paratesticular neoplasm, the adenomatoid tumor, highlighting its varied patterns and recent description of some of the issues that may arise when they undergo total or subtotal infarction.
  • [MeSH-minor] Carcinoma, Embryonal / diagnosis. Carcinoma, Embryonal / pathology. Diagnosis, Differential. Endodermal Sinus Tumor / diagnosis. Endodermal Sinus Tumor / pathology. Humans. Male. Neoplasms, Germ Cell and Embryonal / diagnosis. Neoplasms, Germ Cell and Embryonal / pathology. Seminoma / diagnosis. Seminoma / pathology. Teratoma / diagnosis. Teratoma / pathology

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  • (PMID = 18384207.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 54
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80. Modolo F, Biz MT, Martins MT, Machado de Sousa SO, de Araújo NS: Expression of extracellular matrix proteins in adenomatoid odontogenic tumor. J Oral Pathol Med; 2010 Mar;39(3):230-5
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of extracellular matrix proteins in adenomatoid odontogenic tumor.
  • Altered expression of extracellular matrix (ECM) components has been reported in several pathologies; however, few ECM proteins have been evaluated in adenomatoid odontogenic tumor (AOT).
  • Only the osteonectin was expressed in the epithelial cells.
  • In conclusion, the low expression of the components studied in neoplastic epithelial cells suggests that the epithelial cells act probably as stimulators of the expression by the stroma, which in turn can act as agonist or antagonist of the tumor growth.
  • [MeSH-major] Extracellular Matrix Proteins / analysis. Odontogenic Tumors / pathology
  • [MeSH-minor] Biglycan. Calcinosis / pathology. Connective Tissue / pathology. Cytoplasm / ultrastructure. Decorin. Epithelial Cells / pathology. Gene Expression Regulation, Neoplastic / genetics. Humans. Integrin-Binding Sialoprotein. Osteocalcin / analysis. Osteonectin / analysis. Osteopontin / analysis. Proteoglycans / analysis. Sialoglycoproteins / analysis

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  • (PMID = 20070486.001).
  • [ISSN] 1600-0714
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / BGN protein, human; 0 / Biglycan; 0 / DCN protein, human; 0 / Decorin; 0 / Extracellular Matrix Proteins; 0 / IBSP protein, human; 0 / Integrin-Binding Sialoprotein; 0 / Osteonectin; 0 / Proteoglycans; 0 / Sialoglycoproteins; 104982-03-8 / Osteocalcin; 106441-73-0 / Osteopontin
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81. Ide F, Mishima K, Saito I, Kusama K: Diagnostically challenging epithelial odontogenic tumors: a selective review of 7 jawbone lesions. Head Neck Pathol; 2009 Mar;3(1):18-26

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diagnostically challenging epithelial odontogenic tumors: a selective review of 7 jawbone lesions.
  • Considerable variation in the clinicopathologic presentation of epithelial odontogenic tumors can sometimes be confusing and increase the chance of misdiagnosis.
  • The other globulomaxillary lesion was managed under the erroneous diagnosis of adenomatoid odontogenic tumor and recurred 4 times over an 11-year period.
  • This tumor was found in retrospect to be consistent with an adenoid ameloblastoma with dentinoid.
  • The diagnosis of cystic squamous odontogenic tumor (SOT) occurring as a radicular lesion of an impacted lower third molar was one of exclusion.
  • Of two unsuspected keratocystic odontogenic tumors, one depicted deceptive features of pericoronitis, while the other case has long been in our files with the diagnosis of globulomaxillary SOT.
  • Two cases of primary intraosseous squamous cell carcinoma appeared benign clinically and exhibited unexpected findings; an impacted third molar began to erupt in association with the growth of carcinoma and another periradicular carcinoma showed dentinoid formation.
  • [MeSH-major] Jaw Neoplasms / diagnosis. Odontogenic Tumors / diagnosis

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  • (PMID = 20596984.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 41
  • [Other-IDs] NLM/ PMC2807539
  • [Keywords] NOTNLM ; Clinicopathologic correlation / Diagnostic pitfall / Epithelial odontogenic tumor / Jawbone
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82. Minato H, Nojima T, Kurose N, Kinoshita E: Adenomatoid tumor of the pleura. Pathol Int; 2009 Aug;59(8):567-71

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid tumor of the pleura.
  • A case of adenomatoid tumor of the pleura is reported, and its differential diagnosis from benign and malignant pleural lesions is discussed.
  • A 7 mm, circumscribed tumor had characteristic features of adenomatoid tumor.
  • The tumor was composed of an aggregation of irregularly shaped tubulocystic spaces with fibrous stoma.
  • On immunohistochemistry the tumor cells were positive for AE1/AE3, CAM5.2, vimentin, cytokeratin 5/6, D2-40, calretinin, thrombomodulin, and WT-1, but negative for CEA, Leu M1 (CD15), thyroid transcription factor-1, epithelial membrane antigen, desmin, glucose transporter-1 (GLUT-1), CD31, and CD34.
  • Adenomatoid tumor of the pleura is rare, and the pathogenesis has not been elucidated.
  • Recognition of these benign mesothelial lesions in the pleura is important to avoid misdiagnosis.
  • The immunohistochemistry in the present case supports its mesothelial origin.
  • [MeSH-major] Adenomatoid Tumor / pathology. Neoplasms, Multiple Primary / pathology. Pleural Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Dermatomyositis / complications. Esophageal Neoplasms / complications. Esophageal Neoplasms / pathology. Female. Humans. Immunohistochemistry. Incidental Findings. Liver Cirrhosis, Biliary / complications. Middle Aged

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  • (PMID = 19627540.001).
  • [ISSN] 1440-1827
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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83. Mohamed A, Singh AS, Raubenheimer EJ, Bouckaert MM: Adenomatoid odontogenic tumour: review of the literature and an analysis of 33 cases from South Africa. Int J Oral Maxillofac Surg; 2010 Sep;39(9):843-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumour: review of the literature and an analysis of 33 cases from South Africa.
  • The adenomatoid odontogenic tumour (AOT) is a benign lesion of odontogenic origin.
  • It is a slow growing tumour that results in a painless expansion of the jaws.
  • Of the 746 odontogenic tumours diagnosed, 4% were AOTs.
  • [MeSH-major] Adenoma / ethnology. Mandibular Neoplasms / epidemiology. Maxillary Neoplasms / epidemiology. Odontogenic Tumors / ethnology

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  • [Copyright] Copyright © 2010 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 20638244.001).
  • [ISSN] 1399-0020
  • [Journal-full-title] International journal of oral and maxillofacial surgery
  • [ISO-abbreviation] Int J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Denmark
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84. Leon JE, Mata GM, Fregnani ER, Carlos-Bregni R, de Almeida OP, Mosqueda-Taylor A, Vargas PA: Clinicopathological and immunohistochemical study of 39 cases of Adenomatoid Odontogenic Tumour: a multicentric study. Oral Oncol; 2005 Sep;41(8):835-42
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  • [Title] Clinicopathological and immunohistochemical study of 39 cases of Adenomatoid Odontogenic Tumour: a multicentric study.
  • Adenomatoid Odontogenic Tumour (AOT) is a relatively uncommon odontogenic lesion and few studies describing its cytokeratin profile have been reported in the English-language literature.
  • Calcifying epithelial odontogenic tumour (CEOT)-like areas were found in 36 out of 39 cases, and 10 cases showed positivity for Congo red in polarized light.
  • Vimentin was also expressed in 27 cases and this profile may indicate the existence of a variable phenotype in certain areas of the tumour.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Keratins / metabolism. Mandibular Neoplasms / pathology. Maxillary Neoplasms / pathology. Odontogenic Tumors / pathology

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  • (PMID = 15979930.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 68238-35-7 / Keratins
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85. Manjunath GV, Nandini NM, Sunila: Fine needle aspiration cytology of adenomatoid tumour--a case report with review of literature. Indian J Pathol Microbiol; 2005 Oct;48(4):503-4

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  • [Title] Fine needle aspiration cytology of adenomatoid tumour--a case report with review of literature.
  • Adenomatoid tumours are neoplasms of male and female genital tract with the epididymis being the most common site.
  • These benign tumours are asymptomatic or cause mild symptoms and a palpable mass.
  • Fine needle aspiration of these tumours is very useful to differentiate malignant from benign lesions and helps to avoid unnecessary aggressive surgical procedures.
  • FNAC of these benign epididymal tumours is diagnostic, rapid, reliable, conclusive and cost effective.
  • We are reporting a case of adenomatoid tumour of epididymis in a 41 year old male patient, diagnosed by FNAC and confirmed by histopathology.
  • [MeSH-major] Adenomatoid Tumor / pathology. Epididymis. Genital Neoplasms, Male / pathology

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  • (PMID = 16366111.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] India
  • [Number-of-references] 7
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86. Ide F, Mishima K, Saito I, Kusama K: Rare peripheral odontogenic tumors: report of 5 cases and comprehensive review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2008 Oct;106(4):e22-8
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  • [Title] Rare peripheral odontogenic tumors: report of 5 cases and comprehensive review of the literature.
  • Peripheral odontogenic tumor (POT) is a rarely encountered lesion.
  • We report 5 cases of POT including adenomatoid odontogenic tumor (AOT), keratocystic odontogenic tumor (KCOT), ameloblastic fibroma (AF), developing odontoma (DO), and calcifying cystic odontogenic tumor (CCOT), and also provide a review of relevant literature to define the tumor profile.
  • [MeSH-major] Mandibular Neoplasms / pathology. Maxillary Neoplasms / pathology. Odontogenic Tumors / pathology

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  • (PMID = 18718792.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 44
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87. Neumann V, Löseke S, Tannapfel A: [Medical insurance aspects of peritoneal tumors with particular attention to peritoneal mesotheliomas]. Med Klin (Munich); 2009 Oct 15;104(10):765-71
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  • [Title] [Medical insurance aspects of peritoneal tumors with particular attention to peritoneal mesotheliomas].
  • [Transliterated title] Versicherungsmedizinische Aspekte bei peritonealen Mesotheliomen und sonstigen peritonealen Tumoren.
  • Malignant peritoneal mesotheliomas arise mainly in male patients and the median age of initial diagnosis is about 56 years.
  • Epitheloid subtype predominates in peritoneal mesotheliomas.
  • Asbestos exposure is the best-known and most common risk factor associated with the development of both pleural and peritoneal mesotheliomas and, therefore, about 90% of cases can be assessed as asbestos-associated.
  • Patients with peritoneal mesotheliomas have distinctly higher asbestos burden of the lungs than patients with pleural mesotheliomas.
  • The mean latency period between exposure and diagnosis of peritoneal mesothelioma ranges from 35 to 40 years and is comparable to that of pleural mesothelioma.
  • Mesothelioma of the tunica vaginalis testis also belongs to the group of peritoneal mesotheliomas.
  • No significant evidence exists for the classification of well-differentiated papillary mesothelioma, solitary fibrous tumor, adenomatoid tumor, primary peritoneal serous borderline tumor, and benign multicystic mesothelioma as asbestos-associated tumors.
  • Except malignant mesotheliomas, the induction of other abdominal tumors is independent of an exposure to asbestos dust.
  • [MeSH-major] Asbestosis / epidemiology. Mesothelioma / epidemiology. National Health Programs / statistics & numerical data. Peritoneal Neoplasms / epidemiology

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  • (PMID = 19856150.001).
  • [ISSN] 1615-6722
  • [Journal-full-title] Medizinische Klinik (Munich, Germany : 1983)
  • [ISO-abbreviation] Med. Klin. (Munich)
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 76
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88. Barboza CA, Pereira Pinto L, Freitas Rde A, Costa Ade L, Souza LB: Proliferating cell nuclear antigen (PCNA) and p53 protein expression in ameloblastoma and adenomatoid odontogenic tumor. Braz Dent J; 2005;16(1):56-61
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  • [Title] Proliferating cell nuclear antigen (PCNA) and p53 protein expression in ameloblastoma and adenomatoid odontogenic tumor.
  • In this study, proliferating cell nuclear antigen (PCNA) and p53 protein expressions were analyzed in 16 cases of ameloblastoma and 8 cases of adenomatoid odontogenic tumor (AOT).
  • The cases of ameloblastoma consisted of solid type tumors and histologic arrangements of different subtypes were observed.
  • In some specimens, more than one histologic subtype was identified in the same lesion, and each tumor was categorized according to the predominant cell pattern.
  • The odontogenic tumors were grouped as follows: follicular ameloblastoma (n=7), plexiform ameloblastoma (n=4), acanthomatous + follicular ameloblastoma (n=3), basal cell ameloblastoma (n=2), adenomatoid odontogenic tumor (n=8).
  • [MeSH-major] Ameloblastoma / metabolism. Odontogenic Tumors / metabolism. Proliferating Cell Nuclear Antigen / biosynthesis. Tumor Suppressor Protein p53 / biosynthesis
  • [MeSH-minor] Analysis of Variance. Humans. Immunoenzyme Techniques. Neoplasm Invasiveness. Statistics, Nonparametric

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  • (PMID = 16113935.001).
  • [ISSN] 0103-6440
  • [Journal-full-title] Brazilian dental journal
  • [ISO-abbreviation] Braz Dent J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
  • [Chemical-registry-number] 0 / Proliferating Cell Nuclear Antigen; 0 / Tumor Suppressor Protein p53
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89. Addis B, Roche H: Problems in mesothelioma diagnosis. Histopathology; 2009 Jan;54(1):55-68
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  • [Title] Problems in mesothelioma diagnosis.
  • Many centres are now seeing increasing numbers of patients with malignant mesothelioma.
  • This presents pathologists involved in making the diagnosis with a number of problems, which can be divided into those encountered in making the distinction between mesothelioma and benign changes and those experienced in separating mesotheliomas from other types of epithelial and connective tissue tumours.
  • Immunohistochemistry plays a major role in helping to make the diagnosis, but it should be interpreted with due regard to the clinical setting and radiological features, and with a knowledge of the wide morphological variations seen in mesothelioma.
  • It includes a discussion of some of the less common variants of mesothelioma and other pleural-based tumours that enter into the differential diagnosis.
  • [MeSH-major] Mesothelioma / diagnosis

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  • (PMID = 19054156.001).
  • [ISSN] 1365-2559
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 101
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90. Crippa S, Di Bella C, Faravelli A: Skin adnexal neoplasm closely resembling adenomatoid tumor: a unique occurrence. Int J Surg Pathol; 2006 Apr;14(2):177-8
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  • [Title] Skin adnexal neoplasm closely resembling adenomatoid tumor: a unique occurrence.
  • We describe a primary skin neoplasm located in the left chest wall that closely resembled adenomatoid tumor of male and female genital tract.
  • The tumor involved the dermis and subcutaneous tissue and measured 0.7 cm in greatest diameter.
  • We are unaware of a previous description of this morphologic pattern in a primary skin tumor, which we have interpreted as of skin adnexal and specifically of eccrine sweat gland origin.
  • [MeSH-minor] Adenomatoid Tumor / pathology. Aged. Breast Neoplasms / surgery. Carcinoma, Ductal / surgery. Diagnosis, Differential. Female. Humans. Immunohistochemistry

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  • (PMID = 16703184.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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91. Minhas K, Barakzai A, Qureshi A: Fibromatous periorchitis. J Pak Med Assoc; 2009 Jan;59(1):47-9
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  • Although fibrous pseudotumours of this region are uncommon, they are reported to be the second most common benign paratesticular lesion after adenomatoid tumours.

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  • (PMID = 19213380.001).
  • [ISSN] 0030-9982
  • [Journal-full-title] JPMA. The Journal of the Pakistan Medical Association
  • [ISO-abbreviation] J Pak Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
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92. Asghar S, Qureshi N, Awan A: Benign mesothelioma of peritoneum presenting as a pelvic mass. J Coll Physicians Surg Pak; 2008 Nov;18(11):723-5
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  • [Title] Benign mesothelioma of peritoneum presenting as a pelvic mass.
  • A large solitary multiloculated pelvic cyst in a 40-year-old woman with chronic pelvic pain was diagnosed to be a Multicystic Benign Mesothelioma (MBM) of peritoneum at laparotomy.
  • [MeSH-major] Mesothelioma, Cystic / diagnosis. Ovarian Neoplasms / diagnosis. Pelvic Neoplasms / diagnosis. Pelvic Pain / diagnosis. Peritoneal Neoplasms / diagnosis

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  • (PMID = 18983801.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
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93. Serrano Frago P, Medrano Llorente P, Borque Fernando A, Pascual Llorente M, Allue López M: [Consults by scrotum mass: epididymo lesions]. Actas Urol Esp; 2007 Apr;31(4):420-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In this review we try to update the knowledge about the tumors of epididymis, describing problems in diagnosis and treatment.
  • We present a case of a 39 years old patient who consults by left testicular mass, before the sonogarphy suspect of tumor was made magnetic resonance imaging , wich aimed towards tumorlike injury.
  • Excision of the injury via inguinal was made and the pathologic diagnosis was of adenomatoid tumor.
  • Owing to the few series that appear in literature, and being the commentaries of these tumors about isolated cases, we expose the characteristics of this illustrated case to value the characteristics in diagnosis and treatment to compare them with other cases.
  • [MeSH-major] Adenomatoid Tumor / diagnosis. Epididymis. Genital Neoplasms, Male / diagnosis. Scrotum

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  • (PMID = 17633931.001).
  • [ISSN] 0210-4806
  • [Journal-full-title] Actas urologicas españolas
  • [ISO-abbreviation] Actas Urol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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94. Handschel JG, Depprich RA, Zimmermann AC, Braunstein S, Kübler NR: Adenomatoid odontogenic tumor of the mandible: review of the literature and report of a rare case. Head Face Med; 2005;1:3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumor of the mandible: review of the literature and report of a rare case.
  • Adenomatoid odontogenic tumor (AOT) is a rare odontogenic tumor which is often misdiagnosed as odontogenic cyst.
  • AOT accounts for about 1% until 9% of all odontogenic tumors.
  • [MeSH-major] Adenomatoid Tumor / diagnosis. Mandibular Neoplasms / diagnosis. Odontogenic Tumors / diagnosis

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  • (PMID = 16270916.001).
  • [ISSN] 1746-160X
  • [Journal-full-title] Head & face medicine
  • [ISO-abbreviation] Head Face Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1266042
  • [General-notes] NLM/ Original DateCompleted: 20080519
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95. Ruiz Liso JM, Ruiz Garcia J, Pardo López ML, Vaillo Vinagre A, Gutiérrez Martín A, Bermúdez Villaverde R: [Epididymis trombosed hemangioma in old patient. Presentation of 1 case with conceptual review and of the literature]. Actas Urol Esp; 2008 May;32(5):533-41
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Hemangioma epididimario trombosado en paciente mayor. Presentación de 1 caso con revisión conceptual y de la literatura.
  • INTRODUCTION: Though theoretically in the paratesticular region one can develop any type of benign tumour of soft tissues, they are the lipomas, leiomyomas and adenomatoid tumours the most usual whereas the hemangiomas are less common.
  • We contribute a new case of epididymis intrascrotal hemangioma (HI), valuing the bibliography that allows us to know the incidence and clinic-pathologic characteristics of these tumours.
  • MATERIAL AND METHOD: A 74-year-old patient includes for study with right scrotal tumour, who is practised orchiectomy.
  • Of equal form there is realized a bibliographical examination of this type of tumours across Medline and of not index-linked search with conceptual review and of the literature.
  • Your hystopathologic diagnosis does not present problems, whereas the clinical one and ultrasonographic study, reaches the whole spectrum of tumours, benign and malignant of soft tissues.
  • CONCLUSIONS: The scrotal tumours are necessary a preoperatory clinical and sonographic study completely, in spite of the fact that they are diagnosed the majority after your surgical removal.
  • The complex system of the tissues on the zone paratesticular implies that the differential enclosed diagnosis does not allow to differentiate, malignant tumours of benign.

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  • (PMID = 18605005.001).
  • [ISSN] 0210-4806
  • [Journal-full-title] Actas urologicas españolas
  • [ISO-abbreviation] Actas Urol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 92
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96. Mourali M, Kedous Z, El Fekih C, Ben Haj Hassine A, Ayadi A, Zineb NB: [Unexpected diagnosis of a cystic pelvic mass: benign mesothelioma of the uterus: case report]. Tunis Med; 2010 Aug;88(8):605-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Unexpected diagnosis of a cystic pelvic mass: benign mesothelioma of the uterus: case report].
  • [Transliterated title] Diagnostic Inattendu devant une masse kystique pelvienne : mésotheliome bénin de l’utérus. A propos d’un cas.
  • BACKGROUND: Benign mesothelioma is a rare tumour mostly found in the genital tract.
  • Histologic exam and immnunochemistry concluded to a benign cystic mesothelioma.
  • CONCLUSION: The benign mesothelioma of the uterus is usually discovered in histology, differential diagnosis for solid forms can be made with leiomyoma or adenomyoma, whereas the cystic forms can be discussed essentially with the ovarian cysts.
  • The presence of mesothelial immunophenotype in immunochemistry improves diagnosis.
  • [MeSH-major] Mesothelioma, Cystic. Uterine Neoplasms

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  • (PMID = 20711970.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] Case Reports; Comparative Study; English Abstract; Journal Article
  • [Publication-country] Tunisia
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97. Bansal A, Zakhour HD: Benign mesothelioma of the appendix: an incidental finding in a case of sigmoid diverticular disease. J Clin Pathol; 2006 Jan;59(1):108-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign mesothelioma of the appendix: an incidental finding in a case of sigmoid diverticular disease.
  • Benign multicystic mesothelioma is a well recognised but rare entity.
  • The aim of this report is to describe a case of a small mesothelial proliferation of the peritoneum.
  • An operation was performed for symptomatic sigmoid diverticular disease.
  • Microscopy revealed a benign mesothelioma.
  • [MeSH-major] Appendiceal Neoplasms / diagnosis. Diverticulum / complications. Mesothelioma / diagnosis. Sigmoid Diseases / complications

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  • (PMID = 16394291.001).
  • [ISSN] 0021-9746
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1860251
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98. Weissferdt A, Kalhor N, Suster S, Moran CA: Adenomatoid spindle cell thymomas: a clinicopathological and immunohistochemical study of 20 cases. Am J Surg Pathol; 2010 Oct;34(10):1544-9
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  • [Title] Adenomatoid spindle cell thymomas: a clinicopathological and immunohistochemical study of 20 cases.
  • Twenty cases of adenomatoid spindle cell thymomas are presented.
  • Grossly, the tumors were described as well-defined solid tumor masses surrounded by membranous tissue, which at cut surface show a light tan homogenous surface.
  • Histologically, all tumors showed similar histological features and were characterized by the presence of a spindle cellular proliferation with an "adenomatoid-like" appearance, which at higher magnification showed the presence of cells with a signet-ring cell-like appearance.
  • Seven tumors showed transcapsular invasion, whereas 13 cases were encapsulate.
  • Immunohistochemical studies showed positive staining for broad-spectrum keratin and keratin 7 with only scattered cells positive for calretinin and epithelial membrane antigen.
  • The cases herein described highlight the importance of recognizing this unusual pattern of spindle cell thymomas to avoid misdiagnosis with other tumors, namely, when dealing with small mediastinoscopic biopsies.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / metabolism. Child. Female. Humans. Keratins / metabolism. Male. Middle Aged. Young Adult

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  • (PMID = 20852406.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 68238-35-7 / Keratins
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99. Yang WZ, Cui ZY, Zhang W, Zhou HY, Wang QS, Zhang YQ, Shi XQ: [Diagnosis and treatment of primary epididymal tumor: a report of 35 cases]. Zhonghua Nan Ke Xue; 2010 Jun;16(6):527-30

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Diagnosis and treatment of primary epididymal tumor: a report of 35 cases].
  • OBJECTIVE: To explore the diagnosis and treatment of primary epididymal tumor.
  • METHODS: We retrospectively analyzed the clinical data of 35 cases of pathologically confirmed primary epididymal tumor.
  • Of the total number of patients, 10 underwent tumor excision, 23 received epididymectomy, 1 was treated by simple orchidoepididymectomy, and by radical orchidoepididymectomy with second-stage retroperitoneal lymph node dissection.
  • RESULTS: Postoperative pathology confirmed 33 cases of benign tumor (including 21 adenomatoid tumor, 7 leiomyoma, 4 fibroma, and 1 papillary cystadenoma), and 2 cases of malignancy (1 malignant fibrous histiocytoma and 1 adenocarcinoma).
  • CONCLUSION: Primary epididymal tumor is difficult to be definitely diagnosed preoperatively.
  • Surgical exploration is the first choice for those highly suspected of the disease.
  • Tumor excision or epididymectomy can be considered for benign cases, while radical orchidoepididymectomy with retroperitoneal lymph node dissection is recommended in case of malignancy.

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  • (PMID = 20608358.001).
  • [ISSN] 1009-3591
  • [Journal-full-title] Zhonghua nan ke xue = National journal of andrology
  • [ISO-abbreviation] Zhonghua Nan Ke Xue
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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100. Pereira Gallardo S, Gómez Torres FJ, Torres Olivera FJ: [Cystic lymphangioma of the adrenal glands. Case report]. Arch Esp Urol; 2007 Mar;60(2):187-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Linfangioma quístico de glándula suprarrenal. A propósito de un caso.
  • RESULTS: Lymphangiomas are multicystic lesions covered by endothelium and with serous content, the differential diagnosis of which is mainly established with hemangioma and adenomatoid tumor.

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  • (PMID = 17484487.001).
  • [ISSN] 0004-0614
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] VTD58H1Z2X / Dopamine; X4W3ENH1CV / Norepinephrine
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