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Items 1 to 65 of about 65
1. Vera Sempere FJ, Artes Martínez MJ, Vera Sirera B, Bonet Marco J: Follicular adenomatoid odontogenic tumor: immunohistochemical study. Med Oral Patol Oral Cir Bucal; 2006 Jul;11(4):E305-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Follicular adenomatoid odontogenic tumor: immunohistochemical study.
  • Adenomatoid odontogenic tumor (AOT) is an uncommon benign odontogenic lesion that affects young patients, with female predominance, mainly in second decade, showing a radiolucent unilocular image associated with an unerupted tooth, usually a canine.
  • In spite of previous and confusing denominations, such as adenoameloblastoma or adenomatoid ameloblastic tumor, AOT is a benign tumor with a very low rate of recurrence, that show a peculiar morphological picture (basaloid appearance with glandular-like structures, calcifying areas, and amiloid-like material) that allow its histopathological recognition.
  • [MeSH-major] Mandibular Neoplasms / pathology. Odontogenic Tumors / pathology

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  • (PMID = 16816813.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng; spa
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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2. Batra P, Prasad S, Parkash H: Adenomatoid odontogenic tumour: review and case report. J Can Dent Assoc; 2005 Apr;71(4):250-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumour: review and case report.
  • Adenomatoid odontogenic tumour is a benign (hamartomatous), noninvasive lesion with slow but progressive growth.
  • This report describes a patient with a large adenomatoid odontogenic tumour in the mandible, with the involved mandibular canine being pushed to the contralateral side.
  • The paper also provides a refresher for general dental practitioners about various diagnostic aspects of this tumour and highlights the controversies regarding its origin and management in light of recent findings.
  • [MeSH-major] Mandibular Neoplasms / pathology. Odontogenic Tumors / pathology

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  • (PMID = 15871773.001).
  • [ISSN] 1488-2159
  • [Journal-full-title] Journal (Canadian Dental Association)
  • [ISO-abbreviation] J Can Dent Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Canada
  • [Number-of-references] 29
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3. Avinash Tejasvi ML, Prashanth Shenai K, Chatra L: Atypical case of periapical adenomatoid odontogenic tumour. J Maxillofac Oral Surg; 2010 Mar;9(1):99-101

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Atypical case of periapical adenomatoid odontogenic tumour.
  • The Adenomatoid Odontogenic Tumour (AOT) is a progressively growing asymptomatic benign non-invasive lesion.

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  • [Cites] J Clin Pediatr Dent. 1995 Winter;19(2):139-42 [7577734.001]
  • [Cites] Oral Surg Oral Med Oral Pathol. 1994 Jun;77(6):662-8 [8065735.001]
  • [Cites] Oral Oncol. 1999 Mar;35(2):125-31 [10435145.001]
  • [Cites] J Exp Med. 1905 Feb 1;6(4-6):377-89 [19866977.001]
  • [Cites] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002 Aug;94(2):246-8 [12221394.001]
  • (PMID = 23139581.001).
  • [ISSN] 0972-8279
  • [Journal-full-title] Journal of maxillofacial and oral surgery
  • [ISO-abbreviation] J Maxillofac Oral Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3453703
  • [Keywords] NOTNLM ; AOT / Extrafollicular / Periapical type / Superimposed extrafollicular AOT
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4. Nonaka CF, de Souza LB, Quinderé LB: Adenomatoid odontogenic tumour associated with dentigerous cyst--unusual case report. Braz J Otorhinolaryngol; 2007 Jan-Feb;73(1):129-31

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumour associated with dentigerous cyst--unusual case report.
  • The adenomatoid odontogenic tumor is a relatively uncommon lesion which mainly affects females in their second decade of life, exhibiting predilection for the anterior region of the maxilla.
  • In this paper we present a case of adenomatoid odontogenic tumor associated with a dentigerous cyst affecting the left maxillary region in a 13-year-old female.
  • [MeSH-major] Dentigerous Cyst / pathology. Maxillary Neoplasms / pathology. Odontogenic Tumors / pathology

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  • (PMID = 17505612.001).
  • [ISSN] 1808-8694
  • [Journal-full-title] Brazilian journal of otorhinolaryngology
  • [ISO-abbreviation] Braz J Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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5. Bhandari N, Kothari M: Adenomatoid odontogenic tumour mimicking a periapical cyst in pregnant woman. Singapore Dent J; 2010 Jun;31(1):26-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumour mimicking a periapical cyst in pregnant woman.
  • Adenomatoid odontogenic tumours (AOT) are uncommon odontogenic lesions characterized histologi-cally by duct-like structures derived from the epithelial component of the lesion and can be distinctly classified into follicular, extrafollicular and extraosseous variants (Neville BW, Damm DD, Allen CM, et al.
  • Adenomatoid Odontogenic Tumor.
  • Adenomatoid odontogenic tumor presenting as periapical disease.
  • [MeSH-major] Odontogenic Tumors. Radicular Cyst

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  • [Copyright] Copyright © 2010 Elsevier. Published by Elsevier B.V. All rights reserved.
  • (PMID = 23739254.001).
  • [ISSN] 0377-5291
  • [Journal-full-title] Singapore dental journal
  • [ISO-abbreviation] Singapore Dent J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
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6. Motamedi MH, Shafeie HA, Azizi T: Salvage of an impacted canine associated with an adenomatoid odontogenic tumour: a case report. Br Dent J; 2005 Jul 23;199(2):89-90

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Salvage of an impacted canine associated with an adenomatoid odontogenic tumour: a case report.
  • The adenomatoid odontogenic tumour (AOT) has been known by a number of descriptive names (adenoameloblastoma, ameloblastic adenomatoid tumour, glandular ameloblastoma, and adenomatoid ameloblastoma) since it was first reported and later recognised as a distinct odontogenic lesion unrelated to ameloblastoma.
  • Although it was considered to be a variant of ameloblastoma at one time leading surgeons to perform unduly aggressive surgery, the treatment outcome experience has borne out the benign, nonaggressive nature of this lesion.
  • Thus, it appears needless to extract involved anterior teeth associated with the tumour, especially in children.
  • We have not found such a procedure to have been done for this tumour in the literature.
  • [MeSH-major] Cuspid / pathology. Mandibular Neoplasms / complications. Odontogenic Tumors / complications. Tooth Movement / methods. Tooth, Impacted / etiology

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  • (PMID = 16041334.001).
  • [ISSN] 0007-0610
  • [Journal-full-title] British dental journal
  • [ISO-abbreviation] Br Dent J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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7. Farah-Klibi F, Ferchichi L, Beyâa Rassou H, Zairi I, Rameh S, Adouani A, Ben Jilani SB, Zermani R: [Adenomatoid odontogenic tumor: two cases]. Rev Stomatol Chir Maxillofac; 2007 Feb;108(1):61-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Adenomatoid odontogenic tumor: two cases].
  • INTRODUCTION: Adenomatoid odontogenic tumor, initially referred to as adenoameloblastoma, is a rare and benign odontogenic tumor.
  • CASE REPORTS: We report two cases of adenomatoid odontogenic tumor, which illustrate the radiological and anatomic features of this tumor.
  • DISCUSSION: The clinical, radiological and histological features of adenomatoid odontogenic tumor are distinct from those of ameloblastoma.
  • This tumor is frequently misdiagnosed as other odontogenic cysts or tumors.
  • We discuss the anatomoclinical features and the histogenesis of this rare tumor.
  • [MeSH-major] Mandibular Neoplasms / pathology. Maxillary Neoplasms / pathology. Odontogenic Tumors / pathology

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  • (PMID = 17275864.001).
  • [ISSN] 0035-1768
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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8. Friedrich RE, Zustin J, Scheuer HA: Adenomatoid odontogenic tumour of the mandible. Anticancer Res; 2010 May;30(5):1787-92

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumour of the mandible.
  • Adenomatoid odontogenic tumour (AOT) is a benign tumour of odontogenic origin.
  • Some areas of the tumour were alpha-smooth-muscle-actin positive, indicating a myoepithelial differentiation.
  • Differential diagnosis of AOT to other odontogenic tumours, such as ameloblastoma, is crucial for therapy.
  • [MeSH-major] Mandibular Neoplasms / diagnosis. Odontogenic Tumors / diagnosis

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  • (PMID = 20592380.001).
  • [ISSN] 1791-7530
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Actins; 68238-35-7 / Keratins
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9. Gadewar DR, Srikant N: Adenomatoid odontogenic tumour: tumour or a cyst, a histopathological support for the controversy. Int J Pediatr Otorhinolaryngol; 2010 Apr;74(4):333-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumour: tumour or a cyst, a histopathological support for the controversy.
  • Adenomatoid odontogenic tumour (AOT) is a well-established odontogenic tumour with various clinicopathological variants.
  • AOT quite frequently mimics an odontogenic cyst commonly a dentigerous cyst.
  • In the present paper we review the literature for the AOTs arising in an odontogenic cyst and add to the literature a case of cystic AOT.
  • [MeSH-major] Adenomatoid Tumor / pathology. Maxillary Neoplasms / pathology. Odontogenic Tumors / pathology
  • [MeSH-minor] Child. Humans. Male. Maxillary Diseases / pathology. Odontogenic Cysts / pathology

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  • [CommentIn] Int J Pediatr Otorhinolaryngol. 2010 Jul;74(7):836-7; author reply 837 [20413165.001]
  • (PMID = 20079941.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Ireland
  • [Number-of-references] 34
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10. de Macedo LG, de Macedo NL, do Socorro Ferreira Monteiro A: Fresh-frozen human bone graft for repair of defect after adenomatoid odontogenic tumour removal. Cell Tissue Bank; 2009 Aug;10(3):221-6
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  • [Title] Fresh-frozen human bone graft for repair of defect after adenomatoid odontogenic tumour removal.
  • The aim of this paper was report the clinical, radiographic, and histological case of adenomatoid odontogenic tumour (AOT) in adolescent woman as well as present the reconstructive treatment of AOT using fresh-frozen human bone graft with guided bone regeneration.
  • [MeSH-major] Adenomatoid Tumor / surgery. Bone Regeneration / physiology. Bone Transplantation. Guided Tissue Regeneration, Periodontal. Odontogenic Tumors / surgery

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  • (PMID = 19132551.001).
  • [ISSN] 1573-6814
  • [Journal-full-title] Cell and tissue banking
  • [ISO-abbreviation] Cell Tissue Bank
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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11. Mohamed A, Singh AS, Raubenheimer EJ, Bouckaert MM: Adenomatoid odontogenic tumour: review of the literature and an analysis of 33 cases from South Africa. Int J Oral Maxillofac Surg; 2010 Sep;39(9):843-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumour: review of the literature and an analysis of 33 cases from South Africa.
  • The adenomatoid odontogenic tumour (AOT) is a benign lesion of odontogenic origin.
  • It is a slow growing tumour that results in a painless expansion of the jaws.
  • Of the 746 odontogenic tumours diagnosed, 4% were AOTs.
  • [MeSH-major] Adenoma / ethnology. Mandibular Neoplasms / epidemiology. Maxillary Neoplasms / epidemiology. Odontogenic Tumors / ethnology

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  • [Copyright] Copyright © 2010 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 20638244.001).
  • [ISSN] 1399-0020
  • [Journal-full-title] International journal of oral and maxillofacial surgery
  • [ISO-abbreviation] Int J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Denmark
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12. Kallel R, Ayadi L, Gouiaa N, Chaabouni S, Karray F, Daoud E, Chaari C, Khabir A, Makni S, Boudawara T: [Extrafollicular adenomatoid odontogenic tumour: report of two cases]. Rev Med Brux; 2009 Sep-Oct;30(5):511-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Extrafollicular adenomatoid odontogenic tumour: report of two cases].
  • The purpose of this study was to analysis the clinicopathological features of adenomatoid odontogenic tumour extrafollicular and to discuss the diagnosis pitfull.
  • An exploratory surgical approach was chosen and the final diagnosis was microscopically confirmed to be an extrafollicular variant of adenomatoid odontogenic tumour.
  • The two cases described illustrate clinical and radiographic features of the extrafollicular variant of adenomatoid odontogenic tumour.
  • [MeSH-major] Mandibular Neoplasms / radiography. Odontogenic Tumors / radiography

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  • (PMID = 19998797.001).
  • [ISSN] 0035-3639
  • [Journal-full-title] Revue médicale de Bruxelles
  • [ISO-abbreviation] Rev Med Brux
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Belgium
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13. Leon JE, Mata GM, Fregnani ER, Carlos-Bregni R, de Almeida OP, Mosqueda-Taylor A, Vargas PA: Clinicopathological and immunohistochemical study of 39 cases of Adenomatoid Odontogenic Tumour: a multicentric study. Oral Oncol; 2005 Sep;41(8):835-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinicopathological and immunohistochemical study of 39 cases of Adenomatoid Odontogenic Tumour: a multicentric study.
  • Adenomatoid Odontogenic Tumour (AOT) is a relatively uncommon odontogenic lesion and few studies describing its cytokeratin profile have been reported in the English-language literature.
  • Calcifying epithelial odontogenic tumour (CEOT)-like areas were found in 36 out of 39 cases, and 10 cases showed positivity for Congo red in polarized light.
  • Vimentin was also expressed in 27 cases and this profile may indicate the existence of a variable phenotype in certain areas of the tumour.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Keratins / metabolism. Mandibular Neoplasms / pathology. Maxillary Neoplasms / pathology. Odontogenic Tumors / pathology

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  • (PMID = 15979930.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 68238-35-7 / Keratins
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14. Philipsen HP, Reichart PA, Siar CH, Ng KH, Lau SH, Zhang X, Dhanuthai K, Swasdison S, Jainkittivong A, Meer S, Jivan V, Altini M, Hazarey V, Ogawa I, Takata T, Taylor AA, Godoy H, Delgado WA, Carlos-Bregni R, Macias JF, Matsuzaka K, Sato D, Vargas PA, Adebayo ET: An updated clinical and epidemiological profile of the adenomatoid odontogenic tumour: a collaborative retrospective study. J Oral Pathol Med; 2007 Aug;36(7):383-93

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An updated clinical and epidemiological profile of the adenomatoid odontogenic tumour: a collaborative retrospective study.
  • BACKGROUND: Adenomatoid odontogenic tumour (AOT) is a benign odontogenic jaw lesion.
  • [MeSH-major] Jaw Neoplasms / epidemiology. Odontogenic Tumors / epidemiology

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  • (PMID = 17617830.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] Denmark
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15. Effiom OA, Odukoya O: Adenomatoid odontogenic tumour: a clinico-pathological analysis and melanin pigmentation study of 31 Nigerian cases. Niger Postgrad Med J; 2005 Jun;12(2):131-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumour: a clinico-pathological analysis and melanin pigmentation study of 31 Nigerian cases.
  • AIM: Clinicopathological analysis and melanin pigmentation occurrence in adenomatoid odontogenic tumour (AOT) diagnosed and managed at the Lagos University Teaching Hospital during a 29- year period.
  • RESULTS: AOT is an uncommon type of odontogenic tumour that is commoner in younger age group (8-35 years) with site predilection for the anterior maxilla (64.5%).
  • [MeSH-major] Jaw Neoplasms / pathology. Odontogenic Tumors / pathology. Skin Pigmentation

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  • (PMID = 15997264.001).
  • [ISSN] 1117-1936
  • [Journal-full-title] The Nigerian postgraduate medical journal
  • [ISO-abbreviation] Niger Postgrad Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nigeria
  • [Chemical-registry-number] 0 / Melanins
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16. Cudney N, Persico J, Cordell KG, D'Silva NJ: Adenomatoid odontogenic tumor developing in association with an odontoma: report of a case. Quintessence Int; 2008 Sep;39(8):693-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumor developing in association with an odontoma: report of a case.
  • The adenomatoid odontogenic tumor is an unusual lesion that usually presents in the anterior maxilla.
  • In contrast, the odontoma is the most common odontogenic tumor.
  • The histopathologic findings were consistent with concurrent occurrence of an odontoma and adenomatoid odontogenic tumor.
  • [MeSH-major] Mandibular Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Odontogenic Tumors / pathology

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  • (PMID = 19107257.001).
  • [ISSN] 1936-7163
  • [Journal-full-title] Quintessence international (Berlin, Germany : 1985)
  • [ISO-abbreviation] Quintessence Int
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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17. Crivelini MM, Soubhia AM, Felipini RC: Study on the origin and nature of the adenomatoid odontogenic tumor by immunohistochemistry. J Appl Oral Sci; 2005 Dec;13(4):406-12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Study on the origin and nature of the adenomatoid odontogenic tumor by immunohistochemistry.
  • The adenomatoid odontogenic tumor (AOT) is a clinically benign lesion.
  • Discussions about the AOT hamartomatous or neoplastic nature, and the probable odontogenic epithelial cell it originates from still exist.
  • This research aimed to study and discuss the subject by the immunohistochemical detection of cytokeratins, laminin, collagen IV, PCNA and p53 in 8 tumor samples and 8 dental follicle samples containing reduced enamel epithelium.
  • The results have shown that CK14 labelling indicated differentiation grades for secreting ameloblasts or ameloblasts in the post-secreting stage in the adenomatoid structure of AOT.
  • Laminin, found on the luminal surface of adenomatoid structures, was compatible with the reduced enamel epithelium during the "protective stage of amelogenesis".
  • PCNA specifically labelled the spindled areas and peripheral cords of the AOT, indicating that these areas are responsible for tumor growth.

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  • (PMID = 20865228.001).
  • [ISSN] 1678-7757
  • [Journal-full-title] Journal of applied oral science : revista FOB
  • [ISO-abbreviation] J Appl Oral Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
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18. Friedrich RE, Scheuer HA, Zustin J: Adenomatoid odontogenic tumor (AOT) of maxillary sinus: case report with respect to immunohistochemical findings. In Vivo; 2009 Jan-Feb;23(1):111-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumor (AOT) of maxillary sinus: case report with respect to immunohistochemical findings.
  • This report describes the surgical therapy, clinical course and morphological characteristics of an adenomatoid odontogenic tumor that developed in the maxilla of a 16-year-old patient.
  • The cystic tumor filled the maxillary sinus and was removed with the retained tooth.
  • The tumor showed immunoreactivity for certain types of cytokeratins, vimentin and p63, and was focally immunoreactive for alpha smooth muscle actin and epithelial membrane antigen.
  • [MeSH-major] Maxillary Sinus / pathology. Maxillary Sinus Neoplasms / pathology. Odontogenic Tumors / pathology
  • [MeSH-minor] Adolescent. Biomarkers, Tumor / metabolism. Humans. Male. Treatment Outcome

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  • (PMID = 19368134.001).
  • [ISSN] 0258-851X
  • [Journal-full-title] In vivo (Athens, Greece)
  • [ISO-abbreviation] In Vivo
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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19. Ribeiro BF, Iglesias DP, Nascimento GJ, Galvão HC, Medeiros AM, Freitas RA: Immunoexpression of MMPs-1, -2, and -9 in ameloblastoma and odontogenic adenomatoid tumor. Oral Dis; 2009 Oct;15(7):472-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Immunoexpression of MMPs-1, -2, and -9 in ameloblastoma and odontogenic adenomatoid tumor.
  • OBJECTIVE: The aim of this study was to evaluate and compare the expression of metalloproteinases-1, -2, and -9 in solid ameloblastoma and adenomatoid odontogenic tumor.
  • METHODS: A total of 20 cases of solid ameloblastoma and 10 cases of adenomatoid odontogenic tumors were selected and immunohistochemically assessed.
  • For MMP-2, there was a varied expression, with 80% and 60% of immunoreactive tumor cells in ameloblastoma and adenomatoid odontogenic tumor respectively.
  • Regarding stromal cells, 65% of ameloblastomas and 80% of adenomatoid odontogenic tumors showed positivity.
  • CONCLUSION: The results suggest that these metalloproteinases are related to growth and progression of tumors analyzed, and particularly in ameloblastoma, its highest aggressiveness may be, in part, a result of the active participation of the stromal cells and their products, such as the MMPs studied.
  • [MeSH-major] Ameloblastoma / metabolism. Matrix Metalloproteinase 1 / biosynthesis. Matrix Metalloproteinase 2 / biosynthesis. Matrix Metalloproteinase 9 / biosynthesis. Odontogenic Tumors / metabolism

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  • (PMID = 19522745.001).
  • [ISSN] 1601-0825
  • [Journal-full-title] Oral diseases
  • [ISO-abbreviation] Oral Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] EC 3.4.24.24 / Matrix Metalloproteinase 2; EC 3.4.24.35 / Matrix Metalloproteinase 9; EC 3.4.24.7 / Matrix Metalloproteinase 1
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20. Yilmaz N, Acikgoz A, Celebi N, Zengin AZ, Gunhan O: Extrafollicular adenomatoid odontogenic tumor of the mandible: report of a case. Eur J Dent; 2009 Jan;3(1):71-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extrafollicular adenomatoid odontogenic tumor of the mandible: report of a case.
  • The purpose of this study was to report an extrafollicular adenomatoid odontogenic tumor in the mandibular anterior region in a patient.
  • The rarity of adenomatoid odontogenic tumor may be associated with its slowly growing pattern and symptomless behavior.
  • Therefore, it should be distinguished from more common lesions of odontogenic origin in routine dental examinations.

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  • [Cites] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002 Aug;94(2):246-8 [12221394.001]
  • [Cites] J Oral Pathol Med. 2003 Jan;32(1):55-62 [12558960.001]
  • [Cites] Med Oral Patol Oral Cir Bucal. 2006 Jul;11(4):E305-8 [16816813.001]
  • [Cites] Braz Dent J. 2005;16(3):251-3 [16429194.001]
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  • [Cites] Head Face Med. 2005;1:3 [16270916.001]
  • [Cites] Br Dent J. 2005 Jul 23;199(2):89-90 [16041334.001]
  • [Cites] J Can Dent Assoc. 2005 Apr;71(4):250-3 [15871773.001]
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  • [Cites] Aust Dent J. 1997 Oct;42(5):315-8 [9409047.001]
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  • (PMID = 19262735.001).
  • [ISSN] 1305-7456
  • [Journal-full-title] European journal of dentistry
  • [ISO-abbreviation] Eur J Dent
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Turkey
  • [Other-IDs] NLM/ PMC2647963
  • [Keywords] NOTNLM ; Extrafollicular / Odontogenic / Tumor
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21. Bravo M, White D, Miles L, Cotton R: Adenomatoid odontogenic tumor mimicking a dentigerous cyst. Int J Pediatr Otorhinolaryngol; 2005 Dec;69(12):1685-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumor mimicking a dentigerous cyst.
  • Adenomatoid odontogenic tumor (AOT) is a slow-growing, asymptomatic and uncommon lesion that arises from odontogenic epithelium with inductive effects on connective tissue.
  • [MeSH-major] Dentigerous Cyst / diagnosis. Maxillary Diseases / diagnosis. Maxillary Neoplasms / diagnosis. Odontogenic Tumors / diagnosis. Tooth, Unerupted

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  • (PMID = 15996761.001).
  • [ISSN] 0165-5876
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ireland
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22. Durrani F, Singh R: Intraosseous follicular adenomatoid odontogenic tumour-a case report. Int J Dent; 2009;2009:597483

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intraosseous follicular adenomatoid odontogenic tumour-a case report.
  • The adenomatoid odontogenic tumour is a relatively uncommon lesion which mainly affects females in their second decade of life.
  • In this paper, we present a case of adenomatoid odontogenic tumor affecting the left maxillary region in a 24-year-old female.

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  • [Cites] Aust Dent J. 1997 Oct;42(5):315-8 [9409047.001]
  • [Cites] Oral Oncol. 1999 Mar;35(2):125-31 [10435145.001]
  • [Cites] J Oral Pathol Med. 2003 Jan;32(1):55-62 [12558960.001]
  • [Cites] Int J Oral Maxillofac Surg. 2007 Jan;36(1):20-5 [17156974.001]
  • [Cites] Int J Pediatr Otorhinolaryngol. 2005 Dec;69(12):1685-8 [15996761.001]
  • [Cites] Braz Dent J. 2005;16(3):251-3 [16429194.001]
  • [Cites] J Can Dent Assoc. 2005 Apr;71(4):250-3 [15871773.001]
  • (PMID = 20339578.001).
  • [ISSN] 1687-8736
  • [Journal-full-title] International journal of dentistry
  • [ISO-abbreviation] Int J Dent
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2837896
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23. Modolo F, Biz MT, Martins MT, Machado de Sousa SO, de Araújo NS: Expression of extracellular matrix proteins in adenomatoid odontogenic tumor. J Oral Pathol Med; 2010 Mar;39(3):230-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of extracellular matrix proteins in adenomatoid odontogenic tumor.
  • Altered expression of extracellular matrix (ECM) components has been reported in several pathologies; however, few ECM proteins have been evaluated in adenomatoid odontogenic tumor (AOT).
  • In conclusion, the low expression of the components studied in neoplastic epithelial cells suggests that the epithelial cells act probably as stimulators of the expression by the stroma, which in turn can act as agonist or antagonist of the tumor growth.
  • [MeSH-major] Extracellular Matrix Proteins / analysis. Odontogenic Tumors / pathology

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  • (PMID = 20070486.001).
  • [ISSN] 1600-0714
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / BGN protein, human; 0 / Biglycan; 0 / DCN protein, human; 0 / Decorin; 0 / Extracellular Matrix Proteins; 0 / IBSP protein, human; 0 / Integrin-Binding Sialoprotein; 0 / Osteonectin; 0 / Proteoglycans; 0 / Sialoglycoproteins; 104982-03-8 / Osteocalcin; 106441-73-0 / Osteopontin
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24. Chuan-Xiang Z, Yan G: Adenomatoid odontogenic tumor: a report of a rare case with recurrence. J Oral Pathol Med; 2007 Aug;36(7):440-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumor: a report of a rare case with recurrence.
  • Adenomatoid odontogenic tumor (AOT) is an uncommon tumor of odontogenic origin, composed of odontogenic epithelium in a variety of histoarchitectural patterns, and characterized by slow but progressive growth.
  • The tumor was diagnosed as AOT with well-defined unilocular radiolucency shown in X-ray graphs and solid nodule of cuboidal or columnar cells of odontogenic epithelium forming typical nests or rosette-like structures as well as characteristic duct-like spaces in histologic findings.
  • [MeSH-major] Maxillary Neoplasms / pathology. Neoplasm Recurrence, Local / pathology. Odontogenic Tumors / pathology

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  • (PMID = 17617839.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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25. Jivan V, Altini M, Meer S, Mahomed F: Adenomatoid odontogenic tumor (AOT) originating in a unicystic ameloblastoma: a case report. Head Neck Pathol; 2007 Dec;1(2):146-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumor (AOT) originating in a unicystic ameloblastoma: a case report.
  • The follicular variant of the adenomatoid odontogenic tumor (AOT) is thought to originate from the reduced enamel epithelium of the dental follicle.
  • This paper presents a case of an extra-follicular AOT, which we believe originated from the epithelial lining of a unicystic ameloblastoma, and reviews the literature.
  • The available evidence seems to indicate that some extra-follicular AOTs might arise as secondary phenomena within pre-existing odontogenic cysts or cystic tumors.
  • [MeSH-major] Adenomatoid Tumor / pathology. Ameloblastoma / pathology. Jaw Neoplasms / pathology. Odontogenic Tumors / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / metabolism. Calbindin 2. Humans. Male. Neoplasms, Multiple Primary. S100 Calcium Binding Protein G / metabolism

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  • [Cites] Oral Dis. 2003 Jan;9(1):1-6 [12617250.001]
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  • (PMID = 20614266.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Calbindin 2; 0 / S100 Calcium Binding Protein G
  • [Other-IDs] NLM/ PMC2807512
  • [Keywords] NOTNLM ; Adenomatoid odontogenic tumor / Extra-follicular / Unicystic ameloblastoma
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26. Martínez A, Mosqueda-Taylor A, Marchesani FJ, Brethauer U, Spencer ML: Adenomatoid odontogenic tumor concomitant with cystic complex odontoma: case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2009 Oct;108(4):e25-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumor concomitant with cystic complex odontoma: case report.
  • This case report describes a 10-year-old female patient with an adenomatoid odontogenic tumor developing together with a cystic complex odontoma.
  • [MeSH-major] Mandibular Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Odontogenic Tumors / pathology. Odontoma / pathology

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  • (PMID = 19778732.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Keratin-1; 0 / Keratin-14; 0 / Keratin-19; 0 / Keratin-3; 0 / Keratin-5; 0 / Keratin-8; 0 / Ki-67 Antigen; 147785-83-9 / Keratin-10
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27. Barboza CA, Pereira Pinto L, Freitas Rde A, Costa Ade L, Souza LB: Proliferating cell nuclear antigen (PCNA) and p53 protein expression in ameloblastoma and adenomatoid odontogenic tumor. Braz Dent J; 2005;16(1):56-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Proliferating cell nuclear antigen (PCNA) and p53 protein expression in ameloblastoma and adenomatoid odontogenic tumor.
  • In this study, proliferating cell nuclear antigen (PCNA) and p53 protein expressions were analyzed in 16 cases of ameloblastoma and 8 cases of adenomatoid odontogenic tumor (AOT).
  • The cases of ameloblastoma consisted of solid type tumors and histologic arrangements of different subtypes were observed.
  • In some specimens, more than one histologic subtype was identified in the same lesion, and each tumor was categorized according to the predominant cell pattern.
  • The odontogenic tumors were grouped as follows: follicular ameloblastoma (n=7), plexiform ameloblastoma (n=4), acanthomatous + follicular ameloblastoma (n=3), basal cell ameloblastoma (n=2), adenomatoid odontogenic tumor (n=8).
  • PCNA immunohistochemical expression revealed stronger quantitative labeling index for the follicular ameloblastoma, while for p53 protein the strongest quantitative labeling index was detected in the plexiform type.
  • Nevertheless, statistical analysis using ANOVA and Tukey's test did not detect significant differences (p>0.05) among the histologic subtypes of ameloblastoma.
  • The findings of this study suggest that the different histologic patterns of ameloblastoma did not show a direct correlation with their clinical behavior and consequently with the prognosis of the cases.
  • The results also indicated that the ameloblastoma has greater proliferative potential than the AOT, which can contribute to explain its more aggressive and invasive characteristics.
  • [MeSH-major] Ameloblastoma / metabolism. Odontogenic Tumors / metabolism. Proliferating Cell Nuclear Antigen / biosynthesis. Tumor Suppressor Protein p53 / biosynthesis
  • [MeSH-minor] Analysis of Variance. Humans. Immunoenzyme Techniques. Neoplasm Invasiveness. Statistics, Nonparametric

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  • (PMID = 16113935.001).
  • [ISSN] 0103-6440
  • [Journal-full-title] Brazilian dental journal
  • [ISO-abbreviation] Braz Dent J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
  • [Chemical-registry-number] 0 / Proliferating Cell Nuclear Antigen; 0 / Tumor Suppressor Protein p53
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28. Souza Andrade ES, da Costa Miguel MC, Pinto LP, de Souza LB: Ameloblastoma and adenomatoid odontogenic tumor: the role of alpha2beta1, alpha3beta1, and alpha5beta1 integrins in local invasiveness and architectural characteristics. Ann Diagn Pathol; 2007 Jun;11(3):199-205

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ameloblastoma and adenomatoid odontogenic tumor: the role of alpha2beta1, alpha3beta1, and alpha5beta1 integrins in local invasiveness and architectural characteristics.
  • Ameloblastoma is an odontogenic neoplasm characterized by local invasiveness and a tendency toward recurrence, whereas adenomatoid odontogenic tumor (AOT) is an indolent neoplasm.
  • A difference in the pattern of integrin expression was observed between the various histologic types of ameloblastoma.
  • [MeSH-major] Ameloblastoma / pathology. Integrin alpha2beta1 / physiology. Integrin alpha3beta1 / physiology. Integrin alpha5beta1 / physiology. Jaw Neoplasms / pathology. Odontogenic Tumors / pathology
  • [MeSH-minor] Cell Communication. Gene Expression Regulation, Neoplastic. Humans. Neoplasm Invasiveness. Neoplasm Recurrence, Local / pathology

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  • (PMID = 17498594.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Integrin alpha2beta1; 0 / Integrin alpha3beta1; 0 / Integrin alpha5beta1
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29. Jivan V, Altini M, Meer S: Secretory cells in adenomatoid odontogenic tumour: tissue induction or metaplastic mineralisation? Oral Dis; 2008 Jul;14(5):445-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Secretory cells in adenomatoid odontogenic tumour: tissue induction or metaplastic mineralisation?
  • OBJECTIVE: To undertake a detailed histological investigation of a large series of adenomatoid odontogenic tumours (AOT) to document the frequency and histomorphology of secretory cells which might indicate an inductive capacity.
  • [MeSH-major] Adenoma / pathology. Calcinosis / metabolism. Dental Enamel Proteins / metabolism. Odontogenic Tumors / pathology. Secretory Vesicles / metabolism

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  • (PMID = 18938270.001).
  • [ISSN] 1354-523X
  • [Journal-full-title] Oral diseases
  • [ISO-abbreviation] Oral Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Dental Enamel Proteins
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30. Garg D, Palaskar S, Shetty VP, Bhushan A: Adenomatoid odontogenic tumor - hamartoma or true neoplasm: a case report. J Oral Sci; 2009 Mar;51(1):155-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumor - hamartoma or true neoplasm: a case report.
  • Adenomatoid odontogenic tumor (AOT) is an uncommon tumor of odontogenic origin with a relative frequency of 2.2 - 7.1%.
  • As the histogenesis of AOT is still uncertain, it is sometimes categorized as a hamartomatous lesion rather than a true neoplasm.
  • The tumor showed some unusual and aggressive features that suggested it was a true neoplasm.
  • [MeSH-major] Hamartoma / diagnosis. Maxillary Diseases / diagnosis. Maxillary Neoplasms / diagnosis. Odontogenic Tumors / diagnosis

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  • (PMID = 19325215.001).
  • [ISSN] 1343-4934
  • [Journal-full-title] Journal of oral science
  • [ISO-abbreviation] J Oral Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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31. Kaminagakura E, Costa MS, Lopes MC, de Almeida OP: Extrafollicular adenomatoid odontogenic tumor: a case report. Gen Dent; 2007 Mar-Apr;55(2):141-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extrafollicular adenomatoid odontogenic tumor: a case report.
  • The adenomatoid odontogenic tumor (AOT) is a benign, non-invasive lesion with a slow but progressive growth.
  • This tumor has three variants: follicular, extrafollicular, and peripheral.
  • [MeSH-major] Mandibular Neoplasms / pathology. Odontogenic Tumors / pathology

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  • (PMID = 17333988.001).
  • [ISSN] 0363-6771
  • [Journal-full-title] General dentistry
  • [ISO-abbreviation] Gen Dent
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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32. Handschel JG, Depprich RA, Zimmermann AC, Braunstein S, Kübler NR: Adenomatoid odontogenic tumor of the mandible: review of the literature and report of a rare case. Head Face Med; 2005;1:3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumor of the mandible: review of the literature and report of a rare case.
  • Adenomatoid odontogenic tumor (AOT) is a rare odontogenic tumor which is often misdiagnosed as odontogenic cyst.
  • AOT accounts for about 1% until 9% of all odontogenic tumors.
  • However, AOT frequently resemble other odontogenic lesions such as dentigerous cysts or ameloblastoma.
  • [MeSH-major] Adenomatoid Tumor / diagnosis. Mandibular Neoplasms / diagnosis. Odontogenic Tumors / diagnosis

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  • [Cites] Indian J Dent Res. 1994 Jul-Sep;5(3):89-95 [9495104.001]
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  • (PMID = 16270916.001).
  • [ISSN] 1746-160X
  • [Journal-full-title] Head & face medicine
  • [ISO-abbreviation] Head Face Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1266042
  • [General-notes] NLM/ Original DateCompleted: 20080519
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33. John JB, John RR: Adenomatoid odontogenic tumor associated with dentigerous cyst in posterior maxilla: A case report and review of literature. J Oral Maxillofac Pathol; 2010 Jul;14(2):59-62

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumor associated with dentigerous cyst in posterior maxilla: A case report and review of literature.
  • Adenomatoid odontogenic tumor (AOT)-a benign (hamartomatous) lesion of odontogenic origin-is an uncommon tumor which affects young individuals with a female predominance, mainly in the second decade.

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  • [Cites] J Clin Pediatr Dent. 1998 Fall;23(1):55-8 [10023235.001]
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  • (PMID = 21731264.001).
  • [ISSN] 1998-393X
  • [Journal-full-title] Journal of oral and maxillofacial pathology : JOMFP
  • [ISO-abbreviation] J Oral Maxillofac Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3125061
  • [Keywords] NOTNLM ; Adenomatoid odontogenic tumor / dentigerous cyst / impacted tooth
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34. Sandhu SV, Narang RS, Jawanda M, Rai S: Adenomatoid odontogenic tumor associated with dentigerous cyst of the maxillary antrum: A rare entity. J Oral Maxillofac Pathol; 2010 Jan;14(1):24-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumor associated with dentigerous cyst of the maxillary antrum: A rare entity.
  • Adenomatoid odontogenic tumor (AOT) is an uncommon tumor of odontogenic origin composed of odontogenic epithelium in a variety of histoarchitectural patterns.

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  • (PMID = 21180455.001).
  • [ISSN] 1998-393X
  • [Journal-full-title] Journal of oral and maxillofacial pathology : JOMFP
  • [ISO-abbreviation] J Oral Maxillofac Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2996001
  • [Keywords] NOTNLM ; Adenomatoid odontogenic tumor / dentigerous cyst / maxillary antrum
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35. Santos JN, Lima FO, Romério P, Souza VF: Adenomatoid odontogenic tumor: an unusual case exhibiting cribriform aspect. Quintessence Int; 2008 Oct;39(9):777-81

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumor: an unusual case exhibiting cribriform aspect.
  • The occurrence of areas exhibiting cribriform morphology in odontogenic tumors is not a very frequent finding.
  • Histopathologically, the lesion consisted of a cystic wall exhibiting an odontogenic epithelium lining composed of oval, angular, and elongated cells forming a cribriform pattern.
  • [MeSH-major] Maxillary Neoplasms / pathology. Odontogenic Tumors / pathology

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  • (PMID = 19093052.001).
  • [ISSN] 1936-7163
  • [Journal-full-title] Quintessence international (Berlin, Germany : 1985)
  • [ISO-abbreviation] Quintessence Int
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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36. de Souza Andrade ES, Miguel MC, de Almeida Freitas R, Pereira Pinto L, Batista de Souza L: Immunoexpression of integrins in ameloblastoma, adenomatoid odontogenic tumor, and human tooth germs. Int J Surg Pathol; 2008 Jul;16(3):277-85

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Immunoexpression of integrins in ameloblastoma, adenomatoid odontogenic tumor, and human tooth germs.
  • The expression of integrins alpha2beta1, alpha3beta1, and alpha5beta1 in 30 ameloblastomas (20 solid and 10 unicystic tumors), 12 adenomatoid odontogenic tumors (AOTs), and 5 human tooth germs in different stages of odontogenesis was analyzed.
  • When these two ameloblastoma types were pooled into a single group, the following significant differences were found: immunoexpression of integrin alpha2beta1 was stronger in ameloblastomas than in AOTs and tooth germs, and the expression of integrin alpha5beta1 was stronger in ameloblastomas than in AOTs.
  • The lack of detection of integrin alpha3beta1 in tooth germs and its detection in the odontogenic tumors studied suggest that this integrin might be used as a marker of neoplastic transformation in odontogenic tissues.
  • [MeSH-major] Ameloblastoma / metabolism. Biomarkers, Tumor / metabolism. Jaw Neoplasms / metabolism. Receptors, Collagen / metabolism. Tooth Germ / metabolism

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  • (PMID = 18573784.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Integrin alpha2beta1; 0 / Integrin alpha3beta1; 0 / Integrin alpha5beta1; 0 / Receptors, Collagen
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37. Bartake AR, Punnya VA, Sudeendra P, Rekha K: Two adenomatoid odontogenic tumours of the maxilla: a case report. Br J Oral Maxillofac Surg; 2009 Dec;47(8):638-40

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Two adenomatoid odontogenic tumours of the maxilla: a case report.
  • An adenomatoid odontogenic tumour (AOT) is a well-recognised benign tumour that enlarges slowly.
  • [MeSH-major] Maxillary Neoplasms / diagnosis. Neoplasms, Multiple Primary / diagnosis. Odontogenic Tumors / diagnosis

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  • (PMID = 19131147.001).
  • [ISSN] 1532-1940
  • [Journal-full-title] The British journal of oral & maxillofacial surgery
  • [ISO-abbreviation] Br J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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38. Ladeinde AL, Ajayi OF, Ogunlewe MO, Adeyemo WL, Arotiba GT, Bamgbose BO, Akinwande JA: Odontogenic tumors: a review of 319 cases in a Nigerian teaching hospital. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2005 Feb;99(2):191-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Odontogenic tumors: a review of 319 cases in a Nigerian teaching hospital.
  • OBJECTIVE: This study sought to determine the relative frequency of odontogenic tumors in a Nigerian population and to compare these data with previous reports.
  • STUDY DESIGN: Records of patients seen at the Lagos University Teaching Hospital between January 1980 and December 2003, with histologic diagnosis of odontogenic tumors (based on World Health Organisation classification, 1992), were analyzed.
  • RESULTS: Odontogenic tumors constituted 9.6% of all the biopsies of oral and jaw lesions seen within the period under study.
  • Three hundred and eight (96.6%) were intraosseous, and 11 (3.4%) were peripheral (peripheral odontogenic fibroma=7; peripheral myxoma=3; peripheral ameloblastoma=1).
  • Ameloblastoma with predilection for the mandible was the most frequent odontogenic tumor (63%), followed by adenomatoid odontogenic tumor (AOT) (7.5%), myxoma (6.5%), calcifying epithelial odontogenic cyst (5.3%), and odontogenic fibroma (5.3%).
  • More cases of malignant odontogenic tumors were seen than cases of calcifying epithelial odontogenic tumor and odontomas.
  • The mean ages of patients with AOT, ameloblastic fibroma, and odontoma were significantly lower than those with ameloblastoma ( P<.05).
  • No significant difference was found between the mean ages of patients with benign odontogenic tumors and those with malignant odontogenic tumors ( P=.058).
  • CONCLUSIONS: Odontogenic tumors, especially ameloblastoma, are not considered rare among Nigerians, whereas odontoma, regarded as the most frequent odontogenic tumor in North and South America, is rare.
  • [MeSH-major] Odontogenic Tumors / epidemiology
  • [MeSH-minor] Adolescent. Adult. Age Factors. Aged. Aged, 80 and over. Ameloblastoma / epidemiology. Child. Child, Preschool. Female. Hospitals, Teaching / statistics & numerical data. Humans. Jaw Neoplasms / epidemiology. Male. Mandibular Neoplasms / epidemiology. Middle Aged. Myxoma / epidemiology. Nigeria / epidemiology. Odontogenic Cyst, Calcifying / epidemiology. Odontoma / epidemiology. Retrospective Studies

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  • (PMID = 15660091.001).
  • [ISSN] 1079-2104
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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39. Ide F, Mishima K, Saito I, Kusama K: Diagnostically challenging epithelial odontogenic tumors: a selective review of 7 jawbone lesions. Head Neck Pathol; 2009 Mar;3(1):18-26

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diagnostically challenging epithelial odontogenic tumors: a selective review of 7 jawbone lesions.
  • Considerable variation in the clinicopathologic presentation of epithelial odontogenic tumors can sometimes be confusing and increase the chance of misdiagnosis.
  • There were 2 cases of mistaken identity in our ameloblastoma file.
  • The other globulomaxillary lesion was managed under the erroneous diagnosis of adenomatoid odontogenic tumor and recurred 4 times over an 11-year period.
  • This tumor was found in retrospect to be consistent with an adenoid ameloblastoma with dentinoid.
  • The diagnosis of cystic squamous odontogenic tumor (SOT) occurring as a radicular lesion of an impacted lower third molar was one of exclusion.
  • Of two unsuspected keratocystic odontogenic tumors, one depicted deceptive features of pericoronitis, while the other case has long been in our files with the diagnosis of globulomaxillary SOT.
  • [MeSH-major] Jaw Neoplasms / diagnosis. Odontogenic Tumors / diagnosis
  • [MeSH-minor] Adult. Aged. Diagnostic Errors. Female. Humans. Male. Middle Aged. Odontogenic Cysts / diagnosis. Periodontal Cyst / diagnosis. Retrospective Studies

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  • (PMID = 20596984.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 41
  • [Other-IDs] NLM/ PMC2807539
  • [Keywords] NOTNLM ; Clinicopathologic correlation / Diagnostic pitfall / Epithelial odontogenic tumor / Jawbone
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40. Ide F, Mishima K, Saito I, Kusama K: Rare peripheral odontogenic tumors: report of 5 cases and comprehensive review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2008 Oct;106(4):e22-8
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rare peripheral odontogenic tumors: report of 5 cases and comprehensive review of the literature.
  • Peripheral odontogenic tumor (POT) is a rarely encountered lesion.
  • We report 5 cases of POT including adenomatoid odontogenic tumor (AOT), keratocystic odontogenic tumor (KCOT), ameloblastic fibroma (AF), developing odontoma (DO), and calcifying cystic odontogenic tumor (CCOT), and also provide a review of relevant literature to define the tumor profile.
  • [MeSH-major] Mandibular Neoplasms / pathology. Maxillary Neoplasms / pathology. Odontogenic Tumors / pathology

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  • (PMID = 18718792.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 44
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41. Ernst LM, Quinn PD, Alawi F: Novel oral findings in Schimmelpenning syndrome. Am J Med Genet A; 2007 Apr 15;143A(8):881-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report a patient with Schimmelpenning syndrome with two previously unreported oral manifestations: multiple pigmented malformed teeth and an adenomatoid odontogenic tumor of the anterior mandible.
  • [MeSH-minor] Child, Preschool. Female. Humans. Mandibular Neoplasms / diagnosis. Nevus, Pigmented / diagnosis. Odontogenic Tumors / diagnosis. Syndrome. Tooth Abnormalities / diagnosis

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  • [Copyright] Copyright 2007 Wiley-Liss, Inc.
  • (PMID = 17366580.001).
  • [ISSN] 1552-4825
  • [Journal-full-title] American journal of medical genetics. Part A
  • [ISO-abbreviation] Am. J. Med. Genet. A
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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42. Yeo JF, Rosnah BZ, Ti LS, Zhao YY, Ngeow WC: Clinicopathological study of dentigerous cysts in Singapore and Malaysia. Malays J Pathol; 2007 Jun;29(1):41-7
MedlinePlus Health Information. consumer health - Jaw Injuries and Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Odontogenic keratocysts were observed in 5.0% of cases.
  • One case of adenomatoid odontogenic tumour was also observed.
  • Histopathologically, odontogenic keratocyst and adenomatoid odontogenic tumour were observed in dentigerous cysts.

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  • (PMID = 19105328.001).
  • [ISSN] 0126-8635
  • [Journal-full-title] The Malaysian journal of pathology
  • [ISO-abbreviation] Malays J Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Malaysia
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43. Gomes CC, Oliveira Cda S, Castro WH, de Lacerda JC, Gomez RS: Clonal nature of odontogenic tumours. J Oral Pathol Med; 2009 Apr;38(4):397-400

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clonal nature of odontogenic tumours.
  • BACKGROUND: Although clonal origin is an essential step in the comprehension of neoplasias, there have been no studies to examine whether odontogenic tumours are derived from a single somatic progenitor cell.
  • The purpose of this study was to investigate the clonal origin of odontogenic tumours.
  • METHODS: Fresh samples of seven ameloblastomas, two odontogenic mixomas, two adenomatoid odontogenic tumour, one calcifying odontogenic cyst, one calcifying epithelial odontogenic tumour (CEOT) and six odontogenic keratocyst (OKC) of female patients were included in this study.
  • RESULTS: Most of the informative odontogenic lesions studied (12 out of 16) showed a monoclonal pattern.
  • Among the polyclonal cases, two were OKC, one CEOT and one odontogenic mixoma.
  • CONCLUSIONS: Our results suggest that most odontogenic tumours are monoclonal.
  • [MeSH-major] Odontogenic Tumors / genetics. Odontogenic Tumors / pathology
  • [MeSH-minor] Clone Cells. DNA Methylation. DNA, Neoplasm / analysis. Epigenesis, Genetic. Female. Humans

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  • (PMID = 19298504.001).
  • [ISSN] 1600-0714
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / DNA, Neoplasm
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44. Sriram G, Shetty RP: Odontogenic tumors: a study of 250 cases in an Indian teaching hospital. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2008 Jun;105(6):e14-21

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Odontogenic tumors: a study of 250 cases in an Indian teaching hospital.
  • OBJECTIVE: Studies on odontogenic tumors published from many parts of the world show a distinct geographic variation.
  • But there is little information available in the English-language literature on the relative frequency of odontogenic tumors in India.
  • This retrospective study was designed to determine the relative frequency of odontogenic tumors in an Indian teaching hospital and compare them with various reports from other parts of the world.
  • STUDY DESIGN: The pathology records of the Department of Oral Pathology, Nair Hospital Dental College, from January 1971 to December 2006 were reviewed retrospectively, and based on World Health Organization classifications, 1992, we reclassified and analyzed the odontogenic tumors.
  • The mandible and maxilla were divided into 7 anatomic regions, and the distribution of each odontogenic tumor among these regions was recorded and analyzed.
  • RESULTS: A total of 250 cases of odontogenic tumors were reported in the 36-year period.
  • The most frequent histologic type was ameloblastoma (61.5%), followed by adenomatoid odontogenic tumor (12.4%) and myxomas (6%).
  • Odontomas, which are reported as the most frequent odontogenic tumor in American and European case reports, only accounted for 6%.
  • In general, the odontogenic tumors showed a predilection for the mandible and the posterior regions of the jaws.
  • But adenomatoid odontogenic tumor showed predilection for the maxilla, anterior regions of the jaws, and young females.
  • CONCLUSIONS: Odontogenic tumors show a definite geographic variation.
  • In India, ameloblastoma and adenomatoid odontogenic tumor are the most frequent odontogenic tumors, with distinct anatomic predilections.
  • [MeSH-major] Jaw Neoplasms / epidemiology. Odontogenic Tumors / epidemiology

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  • (PMID = 18417378.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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45. Arunaa S, Ponniah I: Distribution pattern of the adenomatoid odontogenic tumor: a retrospective study from the files of a government teaching hospital, Tamil Nadu, Chennai, India. J Investig Clin Dent; 2010 Aug;1(1):23-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Distribution pattern of the adenomatoid odontogenic tumor: a retrospective study from the files of a government teaching hospital, Tamil Nadu, Chennai, India.
  • AIM: To determine the distribution and clinicopathologic characteristics of adenomatoid odontogenic tumors from Tamil Nadu, India, to provide meaningful data for comparison among different population groups, mainly in the Asian context.
  • METHODS: Forty-three adenomatoid odontogenic tumors were reviewed from 493 odontogenic tumors recorded between 1970 and 2008.
  • The data pertaining to age, sex, anatomic site, associated impacted teeth and radiographic details, provisional diagnoses, and macroscopic and microscopic details of the 43 odontogenic tumors were reviewed.
  • RESULTS: The relative frequency of adenomatoid tumors comprised 8.72% of the total odontogenic tumors.
  • The age range was 9-30 years, with a mean age of 16.88 years for combined adenomatoid odontogenic tumors.
  • The mean age for other variants of adenomatoid odontogenic tumors assessed in this study differed slightly between sexes.
  • For combined adenomatoid odontogenic tumors, the male-to-female ratio was 1:1.26, and the maxilla-to-mandible ratio was 2.9:1.
  • CONCLUSION: The present study shows variations in the distribution of adenomatoid odontogenic tumors within the population assessed, but no definite conclusion emerged with regard to regional or ethnic effect.
  • [MeSH-major] Odontogenic Tumors / epidemiology

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  • [Copyright] © 2010 Blackwell Publishing Asia Pty Ltd.
  • (PMID = 25427183.001).
  • [ISSN] 2041-1626
  • [Journal-full-title] Journal of investigative and clinical dentistry
  • [ISO-abbreviation] J Investig Clin Dent
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
  • [Keywords] NOTNLM ; Asian / Dravidian / India / Tamil Nadu / adenomatoid odontogenic tumor
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46. Moreira PR, Guimarães MM, Gomes CC, Diniz MG, Brito JA, de Castro WH, Gomez RS: Methylation frequencies of cell-cycle associated genes in epithelial odontogenic tumours. Arch Oral Biol; 2009 Oct;54(10):893-7
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Methylation frequencies of cell-cycle associated genes in epithelial odontogenic tumours.
  • OBJECTIVE: The benign epithelial odontogenic tumours constitute a group of lesions derived from epithelial elements of the tooth-forming apparatus.
  • This group includes lesions of different biological behaviour, such as ameloblastoma, calcifying cystic odontogenic tumour (CCOT) and adenomatoid odontogenic tumour (AOT).
  • The aim of this study was to investigate the methylation status of P16, P21, P27, P53 and RB1 genes in epithelial odontogenic tumours.
  • DESIGN: Methylation-specific polymerase chain reaction (MSP) was used to evaluate the presence of methylation in 13 samples of ameloblastoma, six samples of CCOT, three samples of AOT and 14 samples of dental follicles, included as control.
  • In ameloblastoma, the highest methylated genes were P16 and P21, while in CCOT the P21 and RB1 genes were the most commonly methylated genes.
  • A high percentage of the odontogenic tumours analysed showed methylation of the P21 gene, in contrast to dental follicles.
  • CONCLUSIONS: Epithelial odontogenic tumours show a distinct methylation profile in cell-cycle associated genes.
  • In addition to this, the current findings show that epigenetic alterations are common events in epithelial odontogenic tumours.
  • [MeSH-major] Cell Cycle Proteins / genetics. DNA Methylation / genetics. DNA, Neoplasm / metabolism. Neoplasm Proteins / genetics. Odontogenic Tumors / genetics
  • [MeSH-minor] Adenoma / genetics. Adenoma / metabolism. Ameloblastoma / genetics. Ameloblastoma / metabolism. Dental Sac / metabolism. Epithelial Cells / metabolism. Humans. Odontogenic Cyst, Calcifying / genetics. Odontogenic Cyst, Calcifying / metabolism. Polymerase Chain Reaction / methods

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  • (PMID = 19679296.001).
  • [ISSN] 1879-1506
  • [Journal-full-title] Archives of oral biology
  • [ISO-abbreviation] Arch. Oral Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Cell Cycle Proteins; 0 / DNA, Neoplasm; 0 / Neoplasm Proteins
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47. Nigam S, Gupta SK, Chaturvedi KU: Adenomatoid odontogenic tumor--a rare cause of jaw swelling. Braz Dent J; 2005;16(3):251-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumor--a rare cause of jaw swelling.
  • Adenomatoid odontogenic tumor (AOT) is an uncommon tumor of odontogenic origin, characterized histologically by the formation of ductlike structures with amyloid-like deposits.
  • Histogenesis of AOT is still uncertain and it is often considered as a hamartomatous lesion rather than a true neoplasm.
  • [MeSH-major] Maxillary Neoplasms / diagnosis. Odontogenic Tumors / diagnosis

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  • (PMID = 16429194.001).
  • [ISSN] 1806-4760
  • [Journal-full-title] Brazilian dental journal
  • [ISO-abbreviation] Braz Dent J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Brazil
  • [Number-of-references] 8
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48. Andrade FR, Sousa DP, Mendonça EF, Silva TA, Lara VS, Batista AC: Expression of bone resorption regulators (RANK, RANKL, and OPG) in odontogenic tumors. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2008 Oct;106(4):548-55
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of bone resorption regulators (RANK, RANKL, and OPG) in odontogenic tumors.
  • OBJECTIVE: To investigate the expression of bone resorption regulators (receptor activator of nuclear factor kappa B [RANK], RANK ligand [RANKL], and osteoprotegerin [OPG]) in calcifying cystic odontogenic tumor (CCOT), adenomatoid odontogenic tumor (AOT), calcifying epithelial odontogenic tumor (CEOT), odontogenic myxoma (OM), and ameloblastic fibroma (AF).
  • CONCLUSION: Our data indicate that the CCOT, AOT, CEOT, OM, and AF cell constituents express key regulators of bone metabolism that might locally modulate tumor-associated bone resorption.
  • [MeSH-major] Jaw Neoplasms / metabolism. Odontogenic Tumors / metabolism. Osteoprotegerin / biosynthesis. RANK Ligand / biosynthesis. Receptor Activator of Nuclear Factor-kappa B / biosynthesis

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  • (PMID = 18928898.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Osteoprotegerin; 0 / RANK Ligand; 0 / Receptor Activator of Nuclear Factor-kappa B
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49. Buchner A, Merrell PW, Carpenter WM: Relative frequency of central odontogenic tumors: a study of 1,088 cases from Northern California and comparison to studies from other parts of the world. J Oral Maxillofac Surg; 2006 Sep;64(9):1343-52

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Relative frequency of central odontogenic tumors: a study of 1,088 cases from Northern California and comparison to studies from other parts of the world.
  • PURPOSE: To determine the relative frequency of central odontogenic tumors in relation to all biopsy specimens and to one another in an oral pathology biopsy service and to compare the data with previous studies from different parts of the world.
  • Files were systematically searched for all cases of central (intraosseous) odontogenic tumors during a 20-year period.
  • RESULTS: Central odontogenic tumors were identified in 1,088 (1.2%) cases out of the 91,178 accessed.
  • Individually, of all odontogenic tumors, 75.9% were odontomas.
  • The second most common was ameloblastoma (11.7%), followed by odontogenic myxoma (2.2%).
  • When excluded from the list of individual odontogenic tumors, ameloblastoma is the most common (48.5%), followed by odontogenic myxoma (9.2%), adenomatoid odontogenic tumor (7.3%), ameloblastic fibro-odontoma (7.3%), ameloblastic fibroma (6.5%), calcifying odontogenic cyst (6.5%), and odontogenic fibroma (6.1%).
  • Each remaining tumor comprises less than 4%.
  • CONCLUSIONS: Studies related to the relative frequency of individual odontogenic tumors from different parts of the world are difficult to compare because most studies are outdated, the list of tumors is limited, and new entities are not included.
  • To determine the real relative frequency, further studies should be conducted, especially in Western societies, by experienced pathologists in the field of odontogenic tumors.
  • [MeSH-major] Jaw Neoplasms / epidemiology. Odontogenic Tumors / epidemiology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Ameloblastoma / epidemiology. California / epidemiology. Child. Child, Preschool. Global Health. Hamartoma / epidemiology. Humans. Infant. Jaw Diseases / epidemiology. Middle Aged. Odontogenic Cyst, Calcifying / epidemiology. Odontoma / epidemiology. Prevalence. Retrospective Studies. San Francisco / epidemiology

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  • (PMID = 16916667.001).
  • [ISSN] 0278-2391
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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50. Zhong Y, Wang L, Chen XM: [Expression of p-p38MARK, uPA and Ki-67 in epithelial odontogenic tumour]. Zhonghua Kou Qiang Yi Xue Za Zhi; 2010 Sep;45(9):535-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Expression of p-p38MARK, uPA and Ki-67 in epithelial odontogenic tumour].
  • METHODS: the specimens of ameloblastoma (AB), keratocystic odontogenic tumour (KCOT), calcifying epithelial odontogenic tumor (CEOT), adenomatoid odontogenic tumour (AOT), calcifying cystic odontogenic tumour (CCOT) and 5 tooth germs were examined immunohistochemically for the expression of p-p38MAPK, uPA and Ki-67.
  • RESULTS: p-p38MAPK was detected both in the cytoplasm and the nucleus of the epithelial odontogenic tumour cells and uPA in the cytoplasm of the epithelial odontogenic tumour cells.
  • Furthermore, there was a statistically significant difference in the expression of p-p38MAPK, uPA and Ki-67 between epithelial odontogenic tumor group and tooth germ group (P < 0.05).
  • CONCLUSIONS: the p38MAPK-signaling pathway could promote tumour growth and invasion in epithelial odontogenic tumour by up-regulating uPA protein expression and may play a role in oncogenesis, invasion and proliferation of epithelial odontogenic tumour.
  • [MeSH-major] Cell Transformation, Neoplastic. Odontogenic Cyst, Calcifying / metabolism. Odontogenic Tumors / metabolism. Signal Transduction. Skin Neoplasms / metabolism. Urokinase-Type Plasminogen Activator / biosynthesis. p38 Mitogen-Activated Protein Kinases / biosynthesis
  • [MeSH-minor] Ameloblastoma. Epithelial Cells. Humans. Phosphorylation. Tooth Germ

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  • (PMID = 21122446.001).
  • [ISSN] 1002-0098
  • [Journal-full-title] Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
  • [ISO-abbreviation] Zhonghua Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] EC 2.7.11.24 / p38 Mitogen-Activated Protein Kinases; EC 3.4.21.73 / Urokinase-Type Plasminogen Activator; Adenoameloblastoma; Calcifying Epithelial Odontogenic Tumor
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51. Ghasemi-Moridani S, Yazdi I: Adenoid ameloblastoma with dentinoid: a case report. Arch Iran Med; 2008 Jan;11(1):110-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenoid ameloblastoma with dentinoid: a case report.
  • Adenoid ameloblastoma with dentinoid is a rare odontogenic tumor showing histopathologic features similar to ameloblastoma and adenomatoid odontogenic tumor along with hard tissue formation.
  • In this report, a 19-year-old female with a maxillary tumor, microscopically consistent with previously reported cases of adenoid ameloblastoma with dentinoid is presented.
  • [MeSH-major] Ameloblastoma / pathology. Dentin / pathology. Maxillary Neoplasms / pathology

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  • (PMID = 18154432.001).
  • [ISSN] 1029-2977
  • [Journal-full-title] Archives of Iranian medicine
  • [ISO-abbreviation] Arch Iran Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Iran
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52. Jones AV, Franklin CD: An analysis of oral and maxillofacial pathology found in children over a 30-year period. Int J Paediatr Dent; 2006 Jan;16(1):19-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In all, there were 114 benign tumours of nonodontogenic origin, 43 odontogenic tumours and 31 malignant tumours.
  • Odontogenic tumours are relatively rare in this age group; however, certain lesions such as adenomatoid odontogenic tumour and ameloblastic fibroma occur predominantly in children and, therefore, remain an important diagnostic consideration.

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  • (PMID = 16364089.001).
  • [ISSN] 0960-7439
  • [Journal-full-title] International journal of paediatric dentistry
  • [ISO-abbreviation] Int J Paediatr Dent
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] England
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53. Swasdison S, Dhanuthai K, Jainkittivong A, Philipsen HP: Adenomatoid odontogenic tumors: an analysis of 67 cases in a Thai population. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2008 Feb;105(2):210-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumors: an analysis of 67 cases in a Thai population.
  • OBJECTIVE: The aim of this study was to determine the biologic profile of the adenomatoid odontogenic tumor (AOT) in a Thai population.
  • Adenomatoid odontogenic tumors were observed more often on the left side of jaws (50.7% vs. 38.8%).
  • [MeSH-major] Jaw Neoplasms / epidemiology. Jaw Neoplasms / pathology. Odontogenic Tumors / epidemiology. Odontogenic Tumors / pathology

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  • (PMID = 17613261.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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54. Schirmer I, Reichart PA: [Adenomatoid odontogenic tumor (AOT) of the mandible: a surgical follow-up]. Mund Kiefer Gesichtschir; 2007 Nov;11(5):291-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Adenomatoid odontogenic tumor (AOT) of the mandible: a surgical follow-up].
  • [Transliterated title] Chirurgische Verlaufsbeobachtung eines adenomatoid odontogenen Tumors (AOT) im Unterkiefer: Ein Fallbericht.
  • The AOT is a relative rare benign odontogenic tumor.
  • The histological diagnosis of AOT is characterised by odontogenic epithelium, ductlike structures, amyloid-like material and calcifying areas.
  • The histological diagnosis of an AOT was only revealed after a second operation including tumor removal.
  • [MeSH-major] Mandibular Neoplasms / surgery. Odontogenic Tumors / surgery

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  • (PMID = 17828424.001).
  • [ISSN] 1432-9417
  • [Journal-full-title] Mund-, Kiefer- und Gesichtschirurgie : MKG
  • [ISO-abbreviation] Mund Kiefer Gesichtschir
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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55. Saghravanian N, Jafarzadeh H, Bashardoost N, Pahlavan N, Shirinbak I: Odontogenic tumors in an Iranian population: a 30-year evaluation. J Oral Sci; 2010 Sep;52(3):391-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Odontogenic tumors in an Iranian population: a 30-year evaluation.
  • Although the prevalence of odontogenic tumors varies in different geographic sites, there are no reports in English on the relative frequency of odontogenic tumors in Iran.
  • Subsequently, all lesions diagnosed as odontogenic tumors were subjected to microscopic reevaluation.
  • Among 8,766 patients, only 165 odontogenic tumors (1.9%) were found, with a mean age of 26.3 years (range 6-81 years).
  • Malignant transformation was seen in three cases as malignant ameloblastoma (1.8%).
  • The most common tumor was ameloblastoma, followed by odontoma, odontogenic myxoma, and adenomatoid odontogenic tumor.
  • Nevertheless, odontogenic tumors occurred more in females in the third decade with affinity for the posterior mandible in this study.
  • [MeSH-major] Jaw Neoplasms / epidemiology. Odontogenic Tumors / epidemiology

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  • (PMID = 20881331.001).
  • [ISSN] 1880-4926
  • [Journal-full-title] Journal of oral science
  • [ISO-abbreviation] J Oral Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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56. Adebayo ET, Ajike SO, Adekeye EO: A review of 318 odontogenic tumors in Kaduna, Nigeria. J Oral Maxillofac Surg; 2005 Jun;63(6):811-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A review of 318 odontogenic tumors in Kaduna, Nigeria.
  • PURPOSE: To analyze 318 odontogenic tumors seen at a tertiary oral care center in Kaduna, Nigeria for comparison with findings in previous Nigerian and world records.
  • MATERIALS AND METHODS: A retrospective survey of odontogenic tumors based on the classification of Kramer et al was undertaken at the Maxillofacial Unit, Ahmadu Bello University Teaching Hospital, Kaduna, Nigeria, from all histopathologically proven cases of tumors and tumor-like lesions of the oral and perioral structures.
  • RESULTS: There were 990 tumor and tumor-like lesions of the oral and perioral structures, of which 318 were odontogenic tumors (32%).
  • Twelve histopathologic types of odontogenic tumors were found with more benign (n=314; 99%) than malignant (n=4; 1%).
  • Ameloblastoma made up 233 (73%) of the tumors, followed by odontogenic myxoma (n=38; 12%), ameloblastic fibroma (n=9; 3%), and the adenomatoid odontogenic tumor (2%).
  • Three cases of calcifying odontogenic cyst were co-existent with ameloblastoma (2) and ameloblastic fibro-odontoma (1).
  • Among 275 surgically treated odontogenic tumors, enucleation was performed in 64 cases (23%), dentoalveolar segment resection with preservation of lower border of the mandible (n=33; 12%), segmental resection (n=168; 61%), and composite resection (n=9; 3%); 1 case was deemed inoperable.
  • At least 8 cases of ameloblastoma (13%) recurred out of 60 followed up.
  • CONCLUSION: Ameloblastoma is a fairly common tumor of Nigerian Africans accounting for 73% of odontogenic tumors and 24% of all tumors and tumor-like lesions of the oral and perioral structures.
  • Various forms of resection are practiced to eradicate the tumor in view of the late presentation in our environment.
  • A minimum of 5 years of follow-up reviews are necessary after treatment of ameloblastoma.
  • [MeSH-major] Mandibular Neoplasms / pathology. Maxillary Neoplasms / pathology. Odontogenic Tumors / pathology
  • [MeSH-minor] Adolescent. Adult. Age Distribution. Aged. Ameloblastoma / epidemiology. Ameloblastoma / pathology. Child. Female. Fibroma / epidemiology. Fibroma / pathology. Humans. Incidence. Male. Middle Aged. Neoplasm Recurrence, Local. Nigeria / epidemiology. Odontogenic Cyst, Calcifying / epidemiology. Odontogenic Cyst, Calcifying / pathology. Retrospective Studies. Surveys and Questionnaires

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  • [ErratumIn] J Oral Maxillofac Surg. 2005 Dec;63(12):1786
  • (PMID = 15944979.001).
  • [ISSN] 0278-2391
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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57. Gupta B, Ponniah I: The pattern of odontogenic tumors in a government teaching hospital in the southern Indian state of Tamil Nadu. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Jul;110(1):e32-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The pattern of odontogenic tumors in a government teaching hospital in the southern Indian state of Tamil Nadu.
  • OBJECTIVE: This hospital-based study was designed to provide demographic data on odontogenic tumors from the southern Indian population in the state of Tamil Nadu for comparison with pertinent series from other geographic regions.
  • STUDY DESIGN: A total of 489 cases of odontogenic tumors registered over a period of 38 years (February 1970-March 2008) in the Department of Oral and Maxillofacial Pathology of Tamil Nadu Government Dental College and Hospital, Chennai, India, were retrieved from the files of histopathology registers and were retrospectively analyzed.
  • RESULTS: Odontogenic tumors in the present study constituted 4.13% of all the 11,843 registered biopsies.
  • Ameloblastoma with a predilection for posterior mandible was the most frequent odontogenic tumor (67.69%), followed by adenomatoid odontogenic tumor (9%), odontoma (7.77%), and calcifying odontogenic cyst (5.52%).
  • CONCLUSION: The relative frequency of 4.13% of odontogenic tumors observed in this study, which is the largest series from this part of the world.
  • Ameloblastoma formed the single most common tumor of all odontogenic tumors.
  • This study observed both regional and geographic variations in the frequency and distribution of odontogenic tumors.
  • [MeSH-major] Odontogenic Tumors / epidemiology
  • [MeSH-minor] Adolescent. Adult. Age Factors. Aged. Ameloblastoma / epidemiology. Child. Child, Preschool. Female. Hospitals, Public. Hospitals, Teaching. Humans. India / epidemiology. India / ethnology. Male. Mandibular Neoplasms / epidemiology. Maxillary Neoplasms / epidemiology. Middle Aged. Odontogenic Cyst, Calcifying / epidemiology. Odontoma / epidemiology. Population Surveillance. Retrospective Studies. Sex Factors. Young Adult

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  • [Copyright] Copyright (c) 2010 Mosby, Inc. All rights reserved.
  • (PMID = 20610293.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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58. Srikant N: Cystic adenomatoid odontogenic tumour: the master of disguise. Int J Pediatr Otorhinolaryngol; 2010 Jul;74(7):836-7; author reply 837

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cystic adenomatoid odontogenic tumour: the master of disguise.
  • [MeSH-major] Adenomatoid Tumor / pathology. Maxillary Neoplasms / pathology. Odontogenic Tumors / pathology
  • [MeSH-minor] Humans. Odontogenic Cysts / pathology

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  • [CommentOn] Int J Pediatr Otorhinolaryngol. 2010 Apr;74(4):333-7 [20079941.001]
  • (PMID = 20413165.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] Ireland
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59. Nortjé CJ: General practitioner's radiology case 78. Adenomatoid odontogenic tumour. SADJ; 2009 Oct;64(9):414

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] General practitioner's radiology case 78. Adenomatoid odontogenic tumour.
  • [MeSH-major] Maxillary Neoplasms / radiography. Odontogenic Tumors / radiography

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  • (PMID = 20411838.001).
  • [ISSN] 1029-4864
  • [Journal-full-title] SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging
  • [ISO-abbreviation] SADJ
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] South Africa
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60. Ali YH, Hussain AE: Adenomatoid odontogenic tumour of the middle turbinate: case report and literature review. J Otolaryngol Head Neck Surg; 2009 Feb;38(1):E9-13
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumour of the middle turbinate: case report and literature review.
  • [MeSH-major] Adenoma / diagnosis. Bone Neoplasms / diagnosis. Odontogenic Tumors / diagnosis. Turbinates / pathology. Turbinates / radiography

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  • (PMID = 19344604.001).
  • [ISSN] 1916-0216
  • [Journal-full-title] Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
  • [ISO-abbreviation] J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Canada
  • [Number-of-references] 12
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61. Vasconcelos BC, Frota R, Cardoso AB, Porto GG, Carneiro SC: Adenomatoid odontogenic tumor. Braz J Otorhinolaryngol; 2008 Mar-Apr;74(2):315

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid odontogenic tumor.
  • [MeSH-major] Mandibular Neoplasms / diagnostic imaging. Maxillary Sinus Neoplasms / diagnostic imaging. Odontogenic Tumors / diagnostic imaging

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  • (PMID = 18568215.001).
  • [ISSN] 1808-8694
  • [Journal-full-title] Brazilian journal of otorhinolaryngology
  • [ISO-abbreviation] Braz J Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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62. Ide F: Inter-radicular adenomatoid odontogenic tumor of the anterior mandible. J Oral Maxillofac Surg; 2010 Feb;68(2):490-1

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Inter-radicular adenomatoid odontogenic tumor of the anterior mandible.
  • [MeSH-major] Mandibular Neoplasms / pathology. Odontogenic Tumors / pathology

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  • [CommentOn] J Oral Maxillofac Surg. 2009 Sep;67(9):1961-5 [19686935.001]
  • (PMID = 20116733.001).
  • [ISSN] 1531-5053
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Comment; Letter
  • [Publication-country] United States
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63. McGuff HS, Alderson GL, Jones AC, Edgin WA: Oral and maxillofacial pathology case of the month. Adenomatoid odontogenic tumor. Tex Dent J; 2008 Dec;125(12):1192-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Oral and maxillofacial pathology case of the month. Adenomatoid odontogenic tumor.
  • [MeSH-major] Mandibular Neoplasms / diagnosis. Odontogenic Tumors / diagnosis

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  • (PMID = 19227115.001).
  • [ISSN] 0040-4284
  • [Journal-full-title] Texas dental journal
  • [ISO-abbreviation] Tex Dent J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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64. Baughman R: Diagnostic quiz. Case no. 1: adenomatoid odontogenic tumor. Todays FDA; 2006 Aug;18(8):22, 25

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diagnostic quiz. Case no. 1: adenomatoid odontogenic tumor.
  • [MeSH-major] Maxillary Neoplasms / diagnosis. Odontogenic Tumors / diagnosis

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  • (PMID = 19226725.001).
  • [ISSN] 1048-5317
  • [Journal-full-title] Today's FDA : official monthly journal of the Florida Dental Association
  • [ISO-abbreviation] Todays FDA
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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65. Phillips MD, Closmann JJ, Baus MR, Torske KR, Williams SB: Hybrid odontogenic tumor with features of ameloblastic fibro-odontoma, calcifying odontogenic cyst, and adenomatoid odontogenic tumor: a case report and review of the literature. J Oral Maxillofac Surg; 2010 Feb;68(2):470-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hybrid odontogenic tumor with features of ameloblastic fibro-odontoma, calcifying odontogenic cyst, and adenomatoid odontogenic tumor: a case report and review of the literature.
  • [MeSH-major] Mandibular Neoplasms / pathology. Odontogenic Tumors / pathology
  • [MeSH-minor] Adenoma / pathology. Ameloblastoma / pathology. Child. Diagnosis, Differential. Granuloma, Giant Cell / diagnosis. Humans. Male. Odontogenic Cyst, Calcifying / pathology. Odontoma / pathology

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  • (PMID = 20116726.001).
  • [ISSN] 1531-5053
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 15
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