[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 100 of about 318
1. Yantiss RK, Oh KY, Chen YT, Redston M, Odze RD: Filiform serrated adenomas: a clinicopathologic and immunophenotypic study of 18 cases. Am J Surg Pathol; 2007 Aug;31(8):1238-45
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Filiform serrated adenomas: a clinicopathologic and immunophenotypic study of 18 cases.
  • In this study, we describe a previously uncharacterized type of adenomatous polyp of the colorectum that shows prominent, thin, elongated projections of neoplastic epithelium with a serrated contour, which we have termed "filiform serrated adenoma" (SA).
  • Four (22%) filiform SAs also contained nonserrated adenomatous elements with a villous (3 cases) or tubular (1 case) growth pattern.

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17667549.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Neoplasm; 0 / Genetic Markers; EC 2.7.11.1 / BRAF protein, human; EC 2.7.11.1 / Proto-Oncogene Proteins B-raf
  •  go-up   go-down


2. Yang SY, Kim YS, Chung SJ, Song JH, Choi SY, Park MJ, Yim JY, Lim SH, Kim D, Kim CH, Kim JS, Song IS: Association between colorectal adenoma and coronary atherosclerosis detected by CT coronary angiography in Korean men; a cross-sectional study. J Gastroenterol Hepatol; 2010 Nov;25(11):1795-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Association between colorectal adenoma and coronary atherosclerosis detected by CT coronary angiography in Korean men; a cross-sectional study.
  • BACKGROUND: Colorectal adenoma and coronary artery disease (CAD) appear to share common risk factors, such as male gender, diabetes mellitus, smoking, and obesity.
  • We investigated the relationship between colorectal adenoma and coronary atherosclerosis, as a risk factor for colorectal adenoma.
  • The subjects were 488 men (217 colorectal adenoma and 271 normal colonoscopic findings) who underwent colonoscopy and coronary computed tomography angiography (CTA) on the same day as a screening examination.
  • Advanced colonic lesion was defined as a presence of adenoma with villous component, high-grade dysplasia, and/or with size of ≥1 cm.
  • RESULTS: Patients with abnormal CTA findings were more likely to have colorectal adenoma compared with those with normal CTA findings (P < 0.005).
  • Furthermore, presence of advanced adenoma was significantly associated with significant CAD (P < 0.01).
  • On multivariate analyses, abnormal CTA findings (OR = 1.66, 95% CI: 1.14-2.41, P < 0.01) and significant CAD (OR = 1.96, 95% CI: 1.15-3.35, P < 0.05) were found to be independent risk factors for colorectal adenoma after adjusting for age, current smoking, and metabolic syndrome.
  • CONCLUSIONS: In this study, in the population who underwent CTA and colonoscopy for health check-up, prevalence of colorectal adenoma was greater in subjects with low-grade coronary atherosclerosis or significant CAD.
  • The presence of advanced adenoma was significantly associated with significant CAD.
  • [MeSH-major] Adenoma / complications. Adenoma / epidemiology. Colorectal Neoplasms / complications. Colorectal Neoplasms / epidemiology. Coronary Artery Disease / complications. Coronary Artery Disease / epidemiology

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Coronary Artery Disease.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] © 2010 Journal of Gastroenterology and Hepatology Foundation and Blackwell Publishing Asia Pty Ltd.
  • (PMID = 21039843.001).
  • [ISSN] 1440-1746
  • [Journal-full-title] Journal of gastroenterology and hepatology
  • [ISO-abbreviation] J. Gastroenterol. Hepatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
  •  go-up   go-down


3. Lieberman D, Moravec M, Holub J, Michaels L, Eisen G: Polyp size and advanced histology in patients undergoing colonoscopy screening: implications for CT colonography. Gastroenterology; 2008 Oct;135(4):1100-5
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Advanced histology was defined as an adenoma with villous or serrated histology, high-grade dysplasia, or an invasive cancer.

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • COS Scholar Universe. author profiles.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • Faculty of 1000. commentaries/discussion - See the articles recommended by F1000Prime's Faculty of more than 8,000 leading experts in Biology and Medicine. (subscription/membership/fee required).
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Gastroenterology. 2007 Oct;133(4):1077-85 [17698067.001]
  • [Cites] N Engl J Med. 2007 Oct 4;357(14):1403-12 [17914041.001]
  • [Cites] N Engl J Med. 2000 Jul 20;343(3):162-8 [10900274.001]
  • [Cites] N Engl J Med. 2000 Jul 20;343(3):169-74 [10900275.001]
  • [Cites] Gastroenterology. 2003 Feb;124(2):544-60 [12557158.001]
  • [Cites] N Engl J Med. 2003 Dec 4;349(23):2191-200 [14657426.001]
  • [Cites] Gastroenterology. 1990 Feb;98(2):371-9 [2403953.001]
  • [Cites] Am J Gastroenterol. 1993 Apr;88(4):496-500 [8470627.001]
  • [Cites] N Engl J Med. 1993 Dec 30;329(27):1977-81 [8247072.001]
  • [Cites] CA Cancer J Clin. 2008 May-Jun;58(3):130-60 [18322143.001]
  • [Cites] Gastrointest Endosc. 1996 Jan;43(1):25-8 [8903813.001]
  • [Cites] Gastrointest Endosc. 1997 Dec;46(6):492-6 [9434214.001]
  • [Cites] Gastrointest Endosc. 1997 Dec;46(6):497-502 [9434215.001]
  • [Cites] Gastrointest Endosc. 1999 Sep;50(3):314-21 [10462649.001]
  • [Cites] N Engl J Med. 2005 May 19;352(20):2061-8 [15901859.001]
  • [Cites] Gastrointest Endosc. 2006 Jan;63(1):121-33 [16377329.001]
  • [Cites] Clin Gastroenterol Hepatol. 2006 Mar;4(3):343-8 [16527698.001]
  • [Cites] Gastroenterology. 2006 May;130(6):1872-85 [16697750.001]
  • [Cites] N Engl J Med. 2006 Nov 2;355(18):1863-72 [17079760.001]
  • [Cites] AJR Am J Roentgenol. 2007 Apr;188(4):940-4 [17377027.001]
  • [Cites] Hepatogastroenterology. 2007 Mar;54(74):418-21 [17523287.001]
  • [CommentIn] Gastroenterology. 2009 Mar;136(3):1121-2; author reply 122-3 [19167389.001]
  • (PMID = 18691580.001).
  • [ISSN] 1528-0012
  • [Journal-full-title] Gastroenterology
  • [ISO-abbreviation] Gastroenterology
  • [Language] ENG
  • [Grant] United States / NIDDK NIH HHS / DK / R33 DK061778; United States / NIDDK NIH HHS / DK / U01 DK057132-10; United States / NIDDK NIH HHS / DK / UO1 DK57132; United States / NIDDK NIH HHS / DK / U01 DK057132; None / None / / R33 DK061778-01; United States / NIDDK NIH HHS / DK / R33 DK061778-01; United States / NIDDK NIH HHS / DK / R33-DK61778-01; United States / NIDDK NIH HHS / DK / DK057132-10
  • [Publication-type] Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS73580; NLM/ PMC2581902
  •  go-up   go-down


Advertisement
4. Kawakami H, Kuwatani M, Onodera M, Asaka M, Hirano S, Kondo S: Villous adenoma arising in choledochocele. Gastrointest Endosc; 2007 Dec;66(6):1231-2; discussion 1232
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Villous adenoma arising in choledochocele.
  • [MeSH-major] Adenoma, Villous / etiology. Choledochal Cyst / complications. Common Bile Duct Neoplasms / etiology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17681500.001).
  • [ISSN] 0016-5107
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


5. Zorzi M, Grazzini G, Senore C, Vettorazzi M: Screening for colorectal cancer in Italy: 2004 survey. Epidemiol Prev; 2006 Jan-Feb;30(1 Suppl 3):41-50
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • At first screening, the detection rate (DR) per 1000 screened subjects was 2.8 and 11.6 for cancer (CRC) and "high-risk" adenomas (HRA) (> or =3 adenomas, 1 adenoma > or =1 cm, or with villous component >20%, or with high grade dysplasia) respectively; the corresponding figures at repeat screening were 1.2 for CRC and 4.9 for HRA.
  • The DR of CRC and adenomas increased with age and it was higher among men than among women; 51% of screen-detected CRCs were at TNM stage 1.

  • Genetic Alliance. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16937845.001).
  • [ISSN] 1120-9763
  • [Journal-full-title] Epidemiologia e prevenzione
  • [ISO-abbreviation] Epidemiol Prev
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study
  • [Publication-country] Italy
  •  go-up   go-down


6. Cueto J, Benotto JA, Catalina R, Vazquez-Frias JA: Large duodenal villous adenoma requiring head of the pancreas and pylorus-preserving total duodenectomy. Surg Laparosc Endosc Percutan Tech; 2005 Aug;15(4):230-2; discussion 232-3
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Large duodenal villous adenoma requiring head of the pancreas and pylorus-preserving total duodenectomy.
  • Villous adenomas of the duodenum (VAD) are infrequent lesions of the gastrointestinal tract but have a high risk of recurrence and malignancy.
  • PPTD should be an excellent option in patients with large adenomas because it allows preservation of the pancreas, gastrointestinal function is maintained, the possibility of a recurrence and of an invasive carcinoma of the ampulla is eliminated, and finally because it permits an adequate endoscopic follow-up.
  • [MeSH-major] Adenoma, Villous / surgery. Duodenal Neoplasms / surgery. Duodenum / surgery

  • MedlinePlus Health Information. consumer health - Intestinal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16082312.001).
  • [ISSN] 1530-4515
  • [Journal-full-title] Surgical laparoscopy, endoscopy & percutaneous techniques
  • [ISO-abbreviation] Surg Laparosc Endosc Percutan Tech
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


7. Li FE, Ye HJ, Li J, Wang JP, Liu YG, Yu GY, Yin WH: [Clinical, enteroscopic, and pathological characteristics of 796 cases of colorectal polyps]. Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2005 Aug;30(4):463-6
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The canceration rates in villous, mixed and tubular adenomas were 29.73%, 11.11%, and 4.86%.
  • There is a high canceration of polyps in the left colon, villous adenomas and > or = 2.0 cm polyps.
  • [MeSH-minor] Adenoma / pathology. Adolescent. Adult. Aged. Aged, 80 and over. Cell Transformation, Neoplastic / pathology. Child. Child, Preschool. Female. Humans. Male

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16190400.001).
  • [ISSN] 1672-7347
  • [Journal-full-title] Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
  • [ISO-abbreviation] Zhong Nan Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  •  go-up   go-down


8. Qiu HZ, Wu B, Lin GL, Xiao Y: [Therapeutic effects of transsphincteric surgery in treating rectal tumors: a report of 97 cases]. Zhonghua Wai Ke Za Zhi; 2007 Sep 1;45(17):1167-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Pathological examination showed rectal villous adenoma in 35 cases, rectal cancer in 50, rectal carcinoid and others in 12.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18067707.001).
  • [ISSN] 0529-5815
  • [Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]
  • [ISO-abbreviation] Zhonghua Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  •  go-up   go-down


9. Bedoui R, Najah H, Ben AJ, Bouasker I, Hani MA, Nouira R, Zoghlami A, Najah N: [Local transanal excision of large lower rectal villous adenoma]. Tunis Med; 2009 May;87(5):363-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Local transanal excision of large lower rectal villous adenoma].
  • [Transliterated title] Excision locale trans-anale d'un volumineux adénome villeux du bas rectum.
  • [MeSH-major] Adenoma, Villous / surgery. Rectal Neoplasms / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19927774.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Tunisia
  •  go-up   go-down


10. Huang Y, Gong W, Su B, Zhi F, Liu S, Bai Y, Jiang B: Recurrence and surveillance of colorectal adenoma after polypectomy in a southern Chinese population. J Gastroenterol; 2010 Aug;45(8):838-45
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Recurrence and surveillance of colorectal adenoma after polypectomy in a southern Chinese population.
  • BACKGROUND AND AIM: Repeat colonoscopy is often performed within a short time after polypectomy due to the fear that colorectal adenomas were missed during the initial colonoscopy or that new adenomas have developed.
  • The aim of this study was to estimate the actual recurrence rate of adenoma and its association with the length of the surveillance interval after polypectomy in a southern Chinese population.
  • The recurrence rates of adenoma and advanced adenoma and surveillance intervals after polypectomy were identified based on the features of adenomas detected on initial colonoscopy.
  • RESULTS: The recurrence rates of advanced adenoma in patients with non-advanced adenoma on the initial colonoscopy were 0.9, 3.9, 5.8, and 29.2% during surveillance intervals of 1-3, 3-5, 5-10, and 10-20 years post-initial colonoscopy; for patients with advanced adenoma on the initial colonoscopy, the recurrence rates were 3.8, 13.1, 34.7, and 52.0% during the same surveillance intervals, respectively.
  • Older age (p < 0.05 for trend) and male sex [hazard ratio (HR) 2.11, 95% confidence interval (CI) 1.27-3.53] were significantly associated with recurrence for advanced adenoma, as were the size and number of baseline adenoma (p < 0.05 for trend), tubulovillous, villous adenoma (HR 2.57, 95% CI 1.24-5.32), and high-grade dysplasia (HR 1.61, 95% CI 1.07-2.42).
  • When 5% of patients had recurring advanced adenoma, the surveillance interval was estimated to be 6.9 (95% CI 6.3-12.2) years in the low-risk group and 3.0 (95% CI 2.7-3.2) years in the high-risk group.
  • CONCLUSIONS: Among our patient group, the recurrence of advanced adenoma after polypectomy increased with the length of the surveillance interval.
  • Based on our results, a 3-year follow-up of patients after polypectomy could be effective in preventing the recurrence of advanced adenoma in high-risk patients.
  • [MeSH-major] Adenoma / diagnosis. Colonic Polyps / surgery. Colonoscopy / methods. Colorectal Neoplasms / diagnosis

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Am J Gastroenterol. 2009 Aug;104(8):2028-34 [19455125.001]
  • [Cites] BMC Med Res Methodol. 2009 Sep 29;9:66 [19788750.001]
  • [Cites] Gut. 2001 Jun;48(6):753-4 [11358886.001]
  • [Cites] Ann Intern Med. 2008 Mar 18;148(6):419-26 [18347350.001]
  • [Cites] N Engl J Med. 2003 Mar 6;348(10):891-9 [12621133.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2003 Oct;12(10):1006-11 [14578135.001]
  • [Cites] Gastroenterology. 2007 Jan;132(1):96-102 [17241863.001]
  • [Cites] Am J Gastroenterol. 2001 May;96(5):1601-4 [11374706.001]
  • [Cites] Arch Intern Med. 2006 Mar 27;166(6):629-34 [16567601.001]
  • [Cites] Gut. 2002 Sep;51(3):424-8 [12171968.001]
  • [Cites] N Engl J Med. 2004 Mar 4;350(10):991-1004 [14999111.001]
  • [Cites] Gastrointest Endosc. 2010 Jan;71(1):111-7 [19647250.001]
  • [Cites] N Engl J Med. 1993 Dec 30;329(27):1977-81 [8247072.001]
  • [Cites] Cancer Causes Control. 2005 Nov;16(9):1021-33 [16184467.001]
  • [Cites] Gastroenterology. 2001 Apr;120(5):1077-83 [11266371.001]
  • [Cites] Int J Cancer. 2004 Aug 10;111(1):147-51 [15185356.001]
  • [Cites] N Engl J Med. 1993 Apr 1;328(13):901-6 [8446136.001]
  • [Cites] N Engl J Med. 2000 Apr 20;342(16):1149-55 [10770979.001]
  • [Cites] Gastroenterology. 2009 Mar;136(3):832-41 [19171141.001]
  • [Cites] Clin Gastroenterol Hepatol. 2009 Jan;7(1):86-92 [18829395.001]
  • [Cites] Endoscopy. 2008 Apr;40(4):284-90 [18389446.001]
  • [Cites] Gastroenterology. 2006 May;130(6):1865-71 [16697749.001]
  • [Cites] Gastroenterology. 2007 Oct;133(4):1077-85 [17698067.001]
  • [Cites] Gastrointest Endosc. 2000 Apr;51(4 Pt 1):433-7 [10744815.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2005 Sep;14(9):2082-6 [16172213.001]
  • [Cites] CA Cancer J Clin. 2006 May-Jun;56(3):143-59; quiz 184-5 [16737947.001]
  • [Cites] Int J Cancer. 2003 May 20;105(1):82-7 [12672034.001]
  • [Cites] Am J Gastroenterol. 2006 Feb;101(2):343-50 [16454841.001]
  • [Cites] Gastroenterology. 1997 Jan;112(1):24-8 [8978338.001]
  • [Cites] Gastrointest Endosc. 2005 Mar;61(3):385-91 [15758908.001]
  • (PMID = 20336471.001).
  • [ISSN] 1435-5922
  • [Journal-full-title] Journal of gastroenterology
  • [ISO-abbreviation] J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


11. Sasahira T, Akama Y, Fujii K, Kuniyasu H: Expression of receptor for advanced glycation end products and HMGB1/amphoterin in colorectal adenomas. Virchows Arch; 2005 Apr;446(4):411-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of receptor for advanced glycation end products and HMGB1/amphoterin in colorectal adenomas.
  • We studied the expression of RAGE in colorectal adenomas to elucidate the role of RAGE in cancer development.
  • Expressions of RAGE and high-mobility group box-1 (HMGB1)/amphoterin RAGE ligand were examined in 96 colorectal adenomas using immunohistochemistry and in situ hybridization, respectively.
  • Of 96 adenomas, 34 (35%) showed RAGE expression.
  • RAGE positivity was significantly higher in adenomas with severe atypia (18/20, P<0.0001) and large-sized adenomas (-15 mm) (18/22, P<0.0001).
  • Membranous pattern was associated with severe atypia, villous histological type, and co-expression with overexpressed HMGB1/amphoterin.
  • These results suggest that RAGE expression, especially with membranous pattern, is associated with malignant potential of colorectal adenomas.
  • [MeSH-major] Adenoma / metabolism. Colorectal Neoplasms / metabolism. HMGB1 Protein / metabolism. Receptors, Immunologic / metabolism

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Nature. 2000 May 18;405(6784):354-60 [10830965.001]
  • [Cites] J Pathol. 2002 Feb;196(2):163-70 [11793367.001]
  • [Cites] J Cell Sci. 2000 Feb;113 ( Pt 4):611-20 [10652254.001]
  • [Cites] Pathol Int. 1997 Jul;47(7):470-7 [9234386.001]
  • [Cites] Dis Colon Rectum. 1979 Mar;22(2):82-6 [428282.001]
  • [Cites] Biochem Biophys Res Commun. 2004 Apr 9;316(3):949-59 [15033494.001]
  • [Cites] CA Cancer J Clin. 1985 Nov-Dec;35(6):322-44 [3931866.001]
  • [Cites] J Clin Invest. 2001 Oct;108(7):949-55 [11581294.001]
  • [Cites] Oncol Rep. 2003 Mar-Apr;10(2):445-8 [12579287.001]
  • [Cites] Int J Cancer. 2003 May 10;104(6):722-7 [12640679.001]
  • [Cites] Oncol Rep. 2003 Nov-Dec;10(6):1863-8 [14534709.001]
  • [Cites] Semin Thromb Hemost. 2000;26(5):485-93 [11129404.001]
  • [Cites] N Engl J Med. 1988 Sep 1;319(9):525-32 [2841597.001]
  • [Cites] Nature. 1996 Aug 22;382(6593):685-91 [8751438.001]
  • [Cites] J Invest Dermatol. 2004 Feb;122(2):461-7 [15009731.001]
  • (PMID = 15789216.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Advanced Glycosylation End Product-Specific Receptor; 0 / Biomarkers, Tumor; 0 / HMGB1 Protein; 0 / Neoplasm Proteins; 0 / Receptors, Immunologic
  •  go-up   go-down


12. Koning GG, Rensma PL, van Milligen de Wit AW, van Laarhoven CJ: In-one-continuity rectal excision and anal mucosectomy of a giant villous adenoma: an alternative surgical approach. Case Rep Gastroenterol; 2008;2(2):175-80
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] In-one-continuity rectal excision and anal mucosectomy of a giant villous adenoma: an alternative surgical approach.
  • BACKGROUND: The authors present a woman suffering from McKittrick-Wheelock syndrome (MKWS) with a giant rectal villous adenoma.
  • The most frequently reported tumors are villous adenomas.
  • At colonoscopy an 8-cm villous adenoma was seen in the rectum.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Br J Surg. 1980 Sep;67(9):651-2 [7427065.001]
  • [Cites] Rom J Gastroenterol. 2005 Mar;14(1):63-6 [15800695.001]
  • [Cites] Medicina (Kaunas). 2003;39 Suppl 1:48-50 [12761420.001]
  • [Cites] Gastroenterology. 1981 Jun;80(6):1562-6 [7227779.001]
  • [Cites] Prostaglandins. 1992 Jun;43(6):567-72 [1410521.001]
  • [Cites] Med Klin (Munich). 2002 Oct 15;97(10):619-23 [12386796.001]
  • (PMID = 21490885.001).
  • [ISSN] 1662-0631
  • [Journal-full-title] Case reports in gastroenterology
  • [ISO-abbreviation] Case Rep Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Other-IDs] NLM/ PMC3075139
  • [Keywords] NOTNLM ; Dehydration / Electrolyte disorders / McKittrick-Wheelock syndrome / Rectal surgery / Rectal villous adenoma / Renal failure
  •  go-up   go-down


13. Bretagne JF, Manfredi S, Piette C, Hamonic S, Durand G, Riou F: Yield of high-grade dysplasia based on polyp size detected at colonoscopy: a series of 2295 examinations following a positive fecal occult blood test in a population-based study. Dis Colon Rectum; 2010 Mar;53(3):339-45
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE: The aim was to determine the rate of high-grade dysplasia among patients with all adenomas, and its prevalence in patients with adenomas of different sizes in a well-defined population-based study.
  • The rates of high-grade dysplasia were calculated for 3 size categories of adenoma (diminutive, <or=5 mm; small, 6-9 mm; large, >or=10 mm).
  • RESULTS: A total of 1284 adenomas were detected in 784 subjects.
  • High-grade dysplasia was present in 32.1% of the 784 subjects and in 2.7%, 16.0%, and 51.1% of those whose adenomas were diminutive, small, and large, respectively.
  • Among subjects with no more than 2 small adenomas, the proportion of those with high-grade dysplasia was 12.4%.
  • Both adenoma size and a villous component within adenomas were found to be independent predictive factors for high-grade dysplasia by multivariate analysis.
  • CONCLUSIONS: Because of the high rate of high-grade dysplasia among small adenomas, our results reinforce the need to remove all small adenomas detected at colonoscopy.
  • [MeSH-major] Adenoma / pathology. Colonic Polyps / pathology. Colonoscopy

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20173483.001).
  • [ISSN] 1530-0358
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


14. Okamoto M, Kawabe T, Yamaji Y, Kato J, Ikenoue T, Togo G, Yoshida H, Shiratori Y, Omata M: Rectosigmoid findings are not associated with proximal colon cancer: analysis of 6 196 consecutive cases undergoing total colonoscopy. World J Gastroenterol; 2005 Apr 21;11(15):2249-54
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: We estimated the risk of advanced proximal adenomas and cancers in 6 196 consecutive patients that underwent colonoscopy (mean age 60 years, 65% males, without prior history of colorectal examination).
  • Neoplasms were classified as diminutive adenoma (5 mm or less), small adenoma (6-9 mm), advanced adenoma (10 mm or more, with villous component or high-grade dysplasia) and cancer (invasive adenocarcinoma).
  • RESULTS: The trend of the prevalence of advanced proximal adenoma was to increase with severe rectosigmoid findings, while the prevalence of proximal colon cancer did not increase with severe rectosigmoid findings.
  • Multivariate logistic-regression analysis revealed that age was the main predictor of proximal colon cancer and existence of rectosigmoid adenoma was not a predictor of proximal colon cancer.
  • [MeSH-major] Adenoma / epidemiology. Adenoma / pathology. Colonic Neoplasms / epidemiology. Colonic Neoplasms / pathology. Colonoscopy

  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15818734.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC4305807
  •  go-up   go-down


15. Hodadoostan MK, Reza F, Elham M, Mohammad Alizade AH, Molaie M, Mashaiekhy R, Doagoo SZ, Moosavy M, Malek FN, Zali MR: Clinical and pathology characteristics of colorectal polyps in Iranian population. Asian Pac J Cancer Prev; 2010;11(2):557-60
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Adenomas were present in 727 (85%) cases, of these 411 (56%) were left-sided and 316 (44% ) were right-sided.
  • Of the total, 354 were advance polyp (>1cm, villous type, high grade dysplasia), 87(34%) being found in patients under 50 years of age and 149 (58.6 %) being right sided.
  • CONCLUSION: This study showed a significant number of adenomas and carcinomas to lie proximal to the splenic flexure.
  • [MeSH-major] Adenoma / pathology. Colon / pathology. Colonic Polyps / pathology. Colorectal Neoplasms / pathology. Rectum / pathology

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20843151.001).
  • [ISSN] 2476-762X
  • [Journal-full-title] Asian Pacific journal of cancer prevention : APJCP
  • [ISO-abbreviation] Asian Pac. J. Cancer Prev.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Thailand
  •  go-up   go-down


16. Cafferty FH, Wong JM, Yen AM, Duffy SW, Atkin WS, Chen TH: Findings at follow-up endoscopies in subjects with suspected colorectal abnormalities: effects of baseline findings and time to follow-up. Cancer J; 2007 Jul-Aug;13(4):263-70
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Multivariate logistic regression was used to identify risk factors for the following 4 outcomes: any positive findings; multiple (> or =3) polyps; large (> or =10 mm) polyp(s); or villous adenoma(s) or cancer.
  • The number of baseline polyps was a significant risk factor for both positive results and multiple polyps, more severe baseline histology was a risk factor for large polyps and villous adenomas/cancer, and larger baseline polyps were a risk factor for large polyps at follow-up.
  • Interval time was only an independent risk factor for villous adenomas/cancer, which tended to be found at shorter follow-up times.
  • CONCLUSIONS: Results suggest that, with the possible exception of subjects with villous adenomas at baseline, most reexaminations can safely be delayed for > or =5 years.


17. Rubio CA, Nesi G, Messerini L, Zampi GC, Mandai K, Itabashi M, Takubo K: The Vienna classification applied to colorectal adenomas. J Gastroenterol Hepatol; 2006 Nov;21(11):1697-703
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The Vienna classification applied to colorectal adenomas.
  • In this study, that classification is applied to colorectal adenomas.
  • METHODS: Colorectal adenomas from 1552 patients were histologically classified according to the categories listed in Vienna: category 3, low-grade dysplasia; 4.1, high-grade dysplasia; 4.2, carcinoma in situ; 4.3, suspicious of intramucosal carcinoma; 5.1, intramucosal carcinoma; and 5.2, submucosal carcinoma.
  • Adenomas with dysplasia (categories 3 and 4.1) or with carcinoma (categories 4.2, 4.3, 5.1 and 5.2) were analyzed separately.
  • On basis of their configuration, adenomas were classified into tubular, tubulovillous, villous, serrated, microtubular and combined phenotypes (i.e. other than tubulovillous).
  • RESULTS: The highest percentage of adenomas with carcinoma was found amongst villous adenomas (29.6%), followed by combined adenomas (27.8%).
  • Villous adenoma with carcinoma was the most frequent neoplasia at all ages; combined adenomas with carcinoma were more frequent among younger patients.
  • In elderly patients (> or = 60 years of age) the highest percentage of adenomas with carcinoma was recorded in villous adenomas (28.1%), followed by serrated adenomas (19.2%).
  • Villous adenomas and combined adenomas with carcinoma were more frequent in males.
  • CONCLUSION: The Vienna classification of colorectal adenomas seems to be influenced by parameters inherent to the patient such as age and sex and by the histological phenotype of the adenoma.
  • [MeSH-major] Adenoma / classification. Colorectal Neoplasms / classification

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16984592.001).
  • [ISSN] 0815-9319
  • [Journal-full-title] Journal of gastroenterology and hepatology
  • [ISO-abbreviation] J. Gastroenterol. Hepatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
  •  go-up   go-down


18. Hol L, van Leerdam ME, van Ballegooijen M, van Vuuren AJ, van Dekken H, Reijerink JC, van der Togt AC, Habbema JD, Kuipers EJ: Screening for colorectal cancer: randomised trial comparing guaiac-based and immunochemical faecal occult blood testing and flexible sigmoidoscopy. Gut; 2010 Jan;59(1):62-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Colonoscopy was indicated for screenees with a positive gFOBT or FIT, and for those in whom FS revealed a polyp with a diameter > or = 10 mm; adenoma with > or = 25% villous component or high grade dysplasia; serrated adenoma; > or = 3 adenomas; > or = 20 hyperplastic polyps; or CRC.
  • [MeSH-minor] Adenoma / diagnosis. Age Distribution. Aged. Female. Guaiac. Humans. Indicators and Reagents. Male. Middle Aged. Patient Participation / statistics & numerical data. Sex Distribution. Social Class


19. Sonwalkar S, Rotimi O, Rembacken BJ: Characterization of colonic polyps at conventional (nonmagnifying) colonoscopy after spraying with 0.2 % indigo carmine dye. Endoscopy; 2006 Dec;38(12):1218-23
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND AND STUDY AIMS: Japanese endoscopists have devised a classification system based on mucosal crypt patterns which is helpful for distinguishing between hyperplastic polyps, adenomas, and invasive cancers at colonoscopy.
  • Of the 467 adenomas, 377 were tubular, 77 were tubulovillous, 8 were villous and 5 were serrated; 423/467 were correctly identified (sensitivity 91 %).
  • A total of 343 of the 377 tubular lesions were correctly identified as tubular adenomas (sensitivity 90 %), and 46 of the 77 tubulovillous lesions were correctly identified.
  • This finding could result in resource savings in colonoscopic screening.

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • Hazardous Substances Data Bank. INDIGO .
  • Hazardous Substances Data Bank. Indigotindisulfonate sodium .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Endoscopy. 2007 May;39(5):476; author reply 477 [17516357.001]
  • (PMID = 17163322.001).
  • [ISSN] 0013-726X
  • [Journal-full-title] Endoscopy
  • [ISO-abbreviation] Endoscopy
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Coloring Agents; 0 / Indoles; D3741U8K7L / Indigo Carmine
  •  go-up   go-down


20. Hurlstone DP, Sanders DS, Cross SS, George R, Shorthouse AJ, Brown S: A prospective analysis of extended endoscopic mucosal resection for large rectal villous adenomas: an alternative technique to transanal endoscopic microsurgery. Colorectal Dis; 2005 Jul;7(4):339-44
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A prospective analysis of extended endoscopic mucosal resection for large rectal villous adenomas: an alternative technique to transanal endoscopic microsurgery.
  • Patients with T2 or node positive disease were referred for surgery.
  • [MeSH-major] Adenoma, Villous / surgery. Colonoscopy / methods. Intestinal Mucosa / surgery. Rectal Neoplasms / surgery

  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • COS Scholar Universe. author profiles.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15932555.001).
  • [ISSN] 1462-8910
  • [Journal-full-title] Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
  • [ISO-abbreviation] Colorectal Dis
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  •  go-up   go-down


21. Iordache S, Săftoiu A, Ciurea T, Georgescu CV, Ghiluşi M: Predictive parameters for advanced neoplastic adenomas and colorectal cancer in patients with colonic polyps--a study in a tertiary medical centre in the South-West region of Romania. Rom J Morphol Embryol; 2006;47(3):239-43
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Predictive parameters for advanced neoplastic adenomas and colorectal cancer in patients with colonic polyps--a study in a tertiary medical centre in the South-West region of Romania.
  • Although many papers had described the role of colo-rectal adenomas and the risk for colon cancer, there is a lack of data about epidemiological factors, the histological type, the pit-pattern and type of polyps in Romania.
  • In polypoid adenomas the risk of malignant transformation is well known and is increasing over time, with size and villous architecture.
  • In this paper we evaluate the predictive parameters that allowed us to establish a correlation between the macroscopical aspect and histological architecture of adenomas in our geographical area (South-West region of Romania).
  • The morphology of adenomas and multiplicity of polyps also have a prognostic value.
  • In our study the main localization of polyps was in the left colon, while the main histological type was tubulo-villous adenomas.
  • We consider that the significant parameters for dysplasia and malignant lesions are the size of lesions, multiplicity of polyps and villous architecture.
  • [MeSH-major] Adenoma / diagnosis. Colonic Polyps / diagnosis. Colorectal Neoplasms / diagnosis

  • Genetic Alliance. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17308682.001).
  • [ISSN] 1220-0522
  • [Journal-full-title] Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
  • [ISO-abbreviation] Rom J Morphol Embryol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Romania
  •  go-up   go-down


22. Zorzi M, Fedato C, Naldoni C, Sassatelli R, Sassoli De' Bianchi P, Senore C, Visioli CB, Cogo C: Screening for colorectal cancer in Italy: 2007 survey. Epidemiol Prev; 2009 May-Jun;33(3 Suppl 2):57-74
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Among the 914,029 subjects attending screening for the first time, the detection rate (DR) per 1,000 screened subjects was 2.7 for invasive cancer and 12.2 for advanced adenomas (AA, adenomas with a diameter >/=1 cm, with villous/tubulovillous type or with high-grade dysplasia).
  • The DR of cancer and adenomas increased with age and was higher among males; 25% of screen-detected cancers were in TNM stage III+.
  • [MeSH-major] Adenoma / diagnosis. Carcinoma / diagnosis. Colorectal Neoplasms / diagnosis. Mass Screening / statistics & numerical data

  • Genetic Alliance. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19776487.001).
  • [ISSN] 1120-9763
  • [Journal-full-title] Epidemiologia e prevenzione
  • [ISO-abbreviation] Epidemiol Prev
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


23. Tohmé C, Chakhtoura G, Abboud B, Noun R, Sarkis R, Ingea H, Farah P, Ghossain A: [Subtotal or total colectomy as surgical treatment of left-sided occlusive colon cancer]. J Med Liban; 2008 Oct-Dec;56(4):198-202
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • There were five synchronous colon carcinomas (7.5%) and 23 (343%) synchronous tubulous and tubulo-villous adenomas.
  • [MeSH-major] Adenoma / complications. Adenoma / surgery. Adenoma, Villous / complications. Adenoma, Villous / surgery. Colectomy / methods. Colonic Neoplasms / complications. Colonic Neoplasms / surgery. Intestinal Obstruction / surgery. Neoplasms, Multiple Primary / complications. Neoplasms, Multiple Primary / surgery

  • MedlinePlus Health Information. consumer health - Intestinal Obstruction.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19115592.001).
  • [ISSN] 0023-9852
  • [Journal-full-title] Le Journal médical libanais. The Lebanese medical journal
  • [ISO-abbreviation] J Med Liban
  • [Language] fre
  • [Publication-type] Comparative Study; English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] Lebanon
  •  go-up   go-down


24. Lepur D, Klinar I, Mise B, Himbele J, Vranjican Z, Barsić B: McKittrick-Wheelock syndrome: a rare cause of diarrhoea. Eur J Gastroenterol Hepatol; 2006 May;18(5):557-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The most frequently reported tumours are villous adenomas.

  • MedlinePlus Health Information. consumer health - Diarrhea.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Eur J Gastroenterol Hepatol. 2006 Oct;18(10):1047-51 [16957509.001]
  • (PMID = 16607156.001).
  • [ISSN] 0954-691X
  • [Journal-full-title] European journal of gastroenterology & hepatology
  • [ISO-abbreviation] Eur J Gastroenterol Hepatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Isotonic Solutions
  •  go-up   go-down


25. Zuo ZG, Song HY, Xu C, Li J, Ni SC, Chen SQ: [Combination of trans-anal intersphincteric resection and trans-abdominal total mesorectal excision for anus-retained ultra-low rectal tumors]. Zhonghua Wai Ke Za Zhi; 2009 Jul 1;47(13):988-91
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • For pathological types, there were 23 cases of adenocarcinoma (9 well differentiated and 14 moderately differentiated), 1 papillary carcinoma, 2 rectal stromal tumor, 5 rectal villous adenoma with neoplasia and 3 giant villous adenoma.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19957808.001).
  • [ISSN] 0529-5815
  • [Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]
  • [ISO-abbreviation] Zhonghua Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  •  go-up   go-down


26. Popescu A, Orban-Schiopu AM, Becheanu G, Diculescu M: McKittrick-Wheelock syndrome - a rare cause of acute renal failure. Rom J Gastroenterol; 2005 Mar;14(1):63-6
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • AIM: Fluid and electrolyte hypersecretion in the villous adenoma of the rectum is presented in the case of a 74 year old man presenting with a severe fluid imbalance.
  • At sigmoidoscopy, a 6/4 cm villous adenoma of the rectum was found.
  • The surgical removal of the adenoma led to complete recovery of the symptoms.
  • [MeSH-major] Acute Kidney Injury / etiology. Adenoma / complications. Rectal Neoplasms / complications

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15800695.001).
  • [ISSN] 1221-4167
  • [Journal-full-title] Romanian journal of gastroenterology
  • [ISO-abbreviation] Rom J Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Romania
  • [Chemical-registry-number] 0 / Electrolytes
  •  go-up   go-down


27. Bonelli L, Sciallero S, Senore C, Zappa M, Aste H, Andreoni B, Angioli D, Ferraris R, Gasperoni S, Malfitana G, Pennazio M, Atkin W, Segnan N, SCORE Working Group: History of negative colorectal endoscopy and risk of rectosigmoid neoplasms at screening flexible sigmoidoscopy. Int J Colorectal Dis; 2006 Mar;21(2):105-13
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This study is aimed at estimating the risk of distal advanced adenomas (diameter >/=10 mm, villous component >20%, high-grade dysplasia) and cancer at screening flexible sigmoidoscopy in subjects aged 55-64 years who reported pre-screening negative colorectal endoscopy.
  • RESULTS: Eight hundred eighty three of 8,202 subjects (10.8%) reported at least one prescreening negative endoscopy: among them, after 3-5 years, 6-10 years and >10 years intervals between last reported examination and screening endoscopy, the Absolute Risk of advanced adenomas was 1.5%, 0.9% and 0.9%; one cancer was detected (0.1%).
  • Among the 7,319 subjects who did not report prescreening endoscopy the risks of advanced adenoma and cancer were 3.2% and 0.4%, respectively.
  • Subjects with a previous colorectal examination had a 65% decreased risk of advanced adenomas (OR=0.35, 95%CI 0.18-0.66) and a 71% decreased risk of cancer (OR=0.29, 95%CI 0.04-1.12) as compared to those who did not.
  • [MeSH-major] Adenoma, Villous / diagnosis. Colorectal Neoplasms / diagnosis. Mass Screening / methods. Sigmoidoscopy / methods

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Med J Aust. 2002 Apr 15;176(8):371-3 [12041631.001]
  • [Cites] Gastroenterology. 1987 Nov;93(5):1009-13 [3653628.001]
  • [Cites] Eur J Surg Oncol. 2002 Dec;28(8):827-31 [12477473.001]
  • [Cites] Gastroenterology. 1993 Sep;105(3):781-90 [8359649.001]
  • [Cites] Br J Cancer. 2003 Jun 16;88(12):1866-73 [12799628.001]
  • [Cites] J Natl Cancer Inst. 2003 Apr 16;95(8):622-5 [12697855.001]
  • [Cites] Hepatogastroenterology. 2001 Mar-Apr;48(38):437-9 [11379327.001]
  • [Cites] BMJ. 1992 Jan 11;304(6819):87-90 [1737146.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2004 Apr;13(4):654-7 [15066933.001]
  • [Cites] Am J Gastroenterol. 2001 May;96(5):1601-4 [11374706.001]
  • [Cites] Tumori. 1998 May-Jun;84(3):312-34 [9678613.001]
  • [Cites] Lancet. 1993 Mar 20;341(8847):736-40 [8095636.001]
  • [Cites] Eur J Cancer. 2004 Jan;40(2):245-52 [14728939.001]
  • [Cites] Recenti Prog Med. 1989 May;80(5):241-4 [2762661.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2000 Feb;9(2):229-32 [10698488.001]
  • [Cites] BMJ. 1995 Aug 19;311(7003):486-8 [7647645.001]
  • [Cites] N Engl J Med. 1993 Dec 30;329(27):1977-81 [8247072.001]
  • [Cites] Cancer Causes Control. 1998 Aug;9(4):455-62 [9794179.001]
  • [Cites] N Engl J Med. 1992 Mar 5;326(10):658-62 [1736104.001]
  • [Cites] J Natl Cancer Inst. 1992 Oct 21;84(20):1572-5 [1404450.001]
  • [Cites] N Engl J Med. 1992 Mar 5;326(10):653-7 [1736103.001]
  • [Cites] Cancer. 1987 Dec 1;60(11):2848-59 [3677018.001]
  • [Cites] Int J Cancer. 1993 Sep 30;55(3):415-8 [8375925.001]
  • [Cites] J Natl Cancer Inst. 2002 Dec 4;94(23):1763-72 [12464648.001]
  • [Cites] Int J Cancer. 1988 Apr 15;41(4):513-7 [3356486.001]
  • [Cites] J Fam Pract. 2002 Sep;51(9):761-6 [12366896.001]
  • [Cites] Int J Cancer. 1999 Sep 24;83(1):18-29 [10449602.001]
  • [Cites] J Natl Cancer Inst. 1990 Nov 21;82(22):1769-72 [2231773.001]
  • [Cites] Gut. 1999 Mar;44(3):372-6 [10026323.001]
  • [Cites] JAMA. 2003 Jul 2;290(1):41-8 [12837710.001]
  • [Cites] Int J Epidemiol. 1997 Oct;26(5):924-32 [9363511.001]
  • [Cites] Ann Intern Med. 1995 Dec 15;123(12):904-10 [7486484.001]
  • [Cites] Gastroenterology. 2003 Feb;124(2):544-60 [12557158.001]
  • [Cites] Dig Dis Sci. 2003 Dec;48(12):2278-83 [14714613.001]
  • [Cites] Gastroenterology. 1996 Nov;111(5):1178-81 [8898630.001]
  • [Cites] Scand J Gastroenterol. 1999 Apr;34(4):414-20 [10365903.001]
  • [Cites] Gastroenterology. 1997 Jan;112(1):24-8 [8978338.001]
  • [Cites] J Natl Cancer Inst. 1993 Apr 7;85(7):566-70 [8455203.001]
  • [Cites] Cancer. 1975 Dec;36(6):2251-70 [1203876.001]
  • [Cites] Br J Cancer. 2001 Sep 28;85(7):972-6 [11592768.001]
  • [Cites] Lancet. 2002 Apr 13;359(9314):1291-300 [11965274.001]
  • (PMID = 15864604.001).
  • [ISSN] 0179-1958
  • [Journal-full-title] International journal of colorectal disease
  • [ISO-abbreviation] Int J Colorectal Dis
  • [Language] eng
  • [Grant] United Kingdom / Medical Research Council / / G9615910
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  •  go-up   go-down


28. Imperiale TF, Glowinski EA, Lin-Cooper C, Larkin GN, Rogge JD, Ransohoff DF: Five-year risk of colorectal neoplasia after negative screening colonoscopy. N Engl J Med; 2008 Sep 18;359(12):1218-24
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: We identified persons with no adenomas on baseline screening colonoscopy who returned at 5 years for follow-up colonoscopy.
  • Findings were categorized according to the most advanced lesion present: no polyp, a hyperplastic polyp, a tubular adenoma less than 1 cm in diameter, an advanced adenoma (a tubular adenoma > or = 1 cm in diameter or a polyp with villous histologic features or high-grade dysplasia), or a cancer.
  • RESULTS: Baseline screening colonoscopy had identified 2436 persons with no adenomas; 1256 of them (51.6%) were rescreened a mean (+/-SD) of 5.34+/-1.34 years later.
  • One or more adenomas were found in 201 persons (16.0%).
  • A total of 19 advanced adenomas, of which 10 (52.6%) were distal to the splenic flexure, were found in 16 persons (1.3%).
  • The risk of an advanced adenoma did not differ significantly between persons with no polyps at baseline and those with hyperplastic polyps at baseline (1.1% [12 of 1057] and 2.0% [4 of 199], respectively; P=0.30).
  • Men were more likely than women to have any adenoma (tubular less than 1 cm in diameter or advanced) (relative risk, 1.88; 95% CI, 1.42 to 2.51) and to have an advanced adenoma (relative risk, 3.31; 95% CI, 1.02 to 10.8).
  • The risk of advanced adenoma is also low, although it is higher among men than among women.
  • [MeSH-major] Adenocarcinoma / epidemiology. Adenoma / epidemiology. Colonic Polyps / epidemiology. Colonoscopy. Colorectal Neoplasms / epidemiology

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • COS Scholar Universe. author profiles.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] 2008 Massachusetts Medical Society
  • [CommentIn] N Engl J Med. 2008 Dec 11;359(24):2611; author reply 2612 [19090029.001]
  • [CommentIn] N Engl J Med. 2008 Dec 11;359(24):2611; author reply 2612 [19073983.001]
  • [CommentIn] N Engl J Med. 2008 Sep 18;359(12):1285-7 [18799563.001]
  • [CommentIn] N Engl J Med. 2008 Dec 11;359(24):2611-2; author reply 2612 [19090030.001]
  • [ErratumIn] N Engl J Med. 2009 Nov 12;361(20):2004
  • (PMID = 18799558.001).
  • [ISSN] 1533-4406
  • [Journal-full-title] The New England journal of medicine
  • [ISO-abbreviation] N. Engl. J. Med.
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / K24 DK02756
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  •  go-up   go-down


29. Arslan N, Dehdashti F, Siegel BA: FDG uptake in colonic villous adenomas. Ann Nucl Med; 2005 Jun;19(4):331-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] FDG uptake in colonic villous adenomas.
  • Colonic adenomas constitute 70-80% of all colorectal polyps, and their clinical significance relates primarily to their relationship with colorectal cancer.
  • The purpose of this study was to investigate the rate of FDG-PET positivity within colonic villous adenomas.
  • A pathology database search was performed to identify all patients diagnosed with colonic villous adenoma between June 1, 1996 and December 1, 2000.
  • Patients with a pathologic diagnosis of colonic villous adenoma and who also had a FDG-PET study up to 1 month before colonoscopy were included in this study.
  • Of more than 4,000 patients, six patients were diagnosed with colonic adenoma on subsequent colonoscopy following FDG-PET study.
  • Based on the pathological findings, these 6 patients had a total of 2 villous and 9 tubulovillous adenomas.
  • Five of the 6 patients showed foci of increased FDG uptake in the region of the colon that corresponded to the villous adenoma(s) detected on colonoscopy, which accounted for a true-positive rate of 83.3% (5/6 subjects).
  • Focal lesions in the colon seen on FDG-PET examinations need to be investigated further, even though some of these will prove to be villous adenomas rather than colorectal carcinomas.
  • [MeSH-major] Adenoma, Villous / radionuclide imaging. Colorectal Neoplasms / radionuclide imaging. Fluorodeoxyglucose F18 / pharmacokinetics. Positron-Emission Tomography / methods

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16097645.001).
  • [ISSN] 0914-7187
  • [Journal-full-title] Annals of nuclear medicine
  • [ISO-abbreviation] Ann Nucl Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
  •  go-up   go-down


30. Mattar W, Rex DK: Large sessile adenomas are associated with a high prevalence of synchronous advanced adenomas. Clin Gastroenterol Hepatol; 2008 Aug;6(8):877-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Large sessile adenomas are associated with a high prevalence of synchronous advanced adenomas.
  • BACKGROUND & AIMS: The prevalence of synchronous neoplasia in patients with large sessile colorectal adenomas is uncertain.
  • METHODS: We conducted a retrospective single-center review of synchronous neoplastic findings in 190 consecutive patients with intact colons and single large sessile adenomas resected endoscopically.
  • Synchronous polyps were those removed at the colonoscopy that discovered the large sessile adenoma or at any follow-up endoscopic examination within 12 months of discovery of the large sessile adenoma.
  • RESULTS: Seventy-five percent of patients had at least 1 synchronous adenoma, and the 190 patients had a mean of 4 synchronous adenomas.
  • Thirty percent of patients had > or =1 synchronous advanced adenoma (adenoma > or =1 cm in size or with high-grade dysplasia or villous elements).
  • There were a total of 116 synchronous advanced adenomas, including 89 adenomas 10-19 mm in size and 8 that were > or =20 mm in size.
  • CONCLUSIONS: Colonoscopists should be aware that patients with large sessile adenomas have a high prevalence of synchronous advanced neoplasia.
  • [MeSH-major] Adenoma / epidemiology. Adenoma / pathology. Colorectal Neoplasms / epidemiology. Colorectal Neoplasms / pathology. Neoplasms, Multiple Primary / epidemiology. Neoplasms, Multiple Primary / pathology

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18585969.001).
  • [ISSN] 1542-7714
  • [Journal-full-title] Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • [ISO-abbreviation] Clin. Gastroenterol. Hepatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


31. Augoff K, Rabczynski J, Tabola R, Czapla L, Ratajczak K, Grabowski K: Immunohistochemical study of decorin expression in polyps and carcinomas of the colon. Med Sci Monit; 2008 Oct;14(10):CR530-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • It was hypothesized that physiological expression of decorin may be associated with cellular senescence of the colorectal mucosa and that its down-regulation, promoting an increase in cellular proliferation, could participate in the progression of adenoma to adenocarcinoma.
  • MATERIAL/METHODS: Tissue samples were obtained from 41 patients with different types of colonic polyps (6 hyperplastic adenomas, 34 neoplastic adenomas, and 1 adenomatous polyp with focal carcinoma) and 12 patients with colon cancer.
  • RESULTS: Normal and hyperplastic tissues and the majority of tubular adenomas showed strong expression of decorin in the stroma.
  • Adenomas with a villous component showed moderate and very low decorin immunoreactivity.
  • The decrease in decorin reactivity in tubulo-villous adenomas was significant as compared with other polyps and controls.

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18830193.001).
  • [ISSN] 1643-3750
  • [Journal-full-title] Medical science monitor : international medical journal of experimental and clinical research
  • [ISO-abbreviation] Med. Sci. Monit.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / DCN protein, human; 0 / Decorin; 0 / Extracellular Matrix Proteins; 0 / Proteoglycans
  •  go-up   go-down


32. Shih CM, Wu SC, Lee CC, Pan CC: Villous adenoma of the ureter with manifestation of mucus hydroureteronephrosis. J Chin Med Assoc; 2007 Jan;70(1):33-5
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Villous adenoma of the ureter with manifestation of mucus hydroureteronephrosis.
  • Villous adenoma is most frequently found in the colon and rectum, seldom in the urinary tract and even more rarely in the ureter or pelvis.
  • The ureteral tumor proved to be villous adenoma by pathologic examination.
  • It should be noted that ureteral villous adenoma may be related to previous enteric-type metaplastic mucosa or ureteritis glandularis, demonstrates profuse production of mucus, and may eventually undergo malignant transformation.
  • [MeSH-major] Adenoma, Villous / complications. Hydronephrosis / etiology. Ureteral Neoplasms / complications

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17276931.001).
  • [ISSN] 1726-4901
  • [Journal-full-title] Journal of the Chinese Medical Association : JCMA
  • [ISO-abbreviation] J Chin Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
  •  go-up   go-down


33. Rainis T, Keren D, Goldstein O, Stermer E, Lavy A: Diagnostic yield and safety of colonoscopy in Israeli patients in an open access referral system. J Clin Gastroenterol; 2007 Apr;41(4):394-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • 2336 polyps were removed, including 18% hyperplastic, 26% tubular adenomata, 13% villous adenomata, 11% tubulovillous adenomata.
  • Advanced disease was found in 41% of pathologic findings, 11% were invasive cancer.

  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17413609.001).
  • [ISSN] 0192-0790
  • [Journal-full-title] Journal of clinical gastroenterology
  • [ISO-abbreviation] J. Clin. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


34. Mila R, Grille S, Laurini M, Lapiedra D, Bagattini JC: [McKittrick- Wheelock syndrome: report of one case]. Rev Med Chil; 2008 Jul;136(7):900-4
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Villous colorectal adenomas are common tumors that normally provoke scarce symptomatology.
  • Colonoscopy confirmed the presence of a villous adenoma that was excised surgically.
  • In this patient, the fluid and electrolyte hypersecretion of the rectal villous adenoma provoked a depletion syndrome with serious hydroelectrolytic alterations, acute renal failure and hypovolemic shock.
  • [MeSH-major] Adenoma, Villous / complications. Colonic Neoplasms / complications. Water-Electrolyte Imbalance / etiology

  • MedlinePlus Health Information. consumer health - Fluid and Electrolyte Balance.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18949168.001).
  • [ISSN] 0034-9887
  • [Journal-full-title] Revista médica de Chile
  • [ISO-abbreviation] Rev Med Chil
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Chile
  •  go-up   go-down


35. Koebrugge B, Bosscha K, Ernst MF: Transanal endoscopic microsurgery for local excision of rectal lesions: is there a learning curve? Dig Surg; 2009;26(5):372-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • All patients undergoing TEM for tubulovillous adenoma or carcinoma between 2002 and 2007 were included.
  • Postoperative staging revealed 77 tubulovillous adenomas, 22 stage T1, 5 stage T2 and 1 stage T3 carcinomas; tumor resection was radical in 86%.
  • [MeSH-major] Adenoma, Villous / surgery. Carcinoma / surgery. Microsurgery / methods. Proctoscopy / methods. Rectal Neoplasms / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2009 S. Karger AG, Basel.
  • (PMID = 19923824.001).
  • [ISSN] 1421-9883
  • [Journal-full-title] Digestive surgery
  • [ISO-abbreviation] Dig Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  •  go-up   go-down


36. Einspahr JG, Martinez ME, Jiang R, Hsu CH, Rashid A, Bhattacharrya AK, Ahnen DJ, Jacobs ET, Houlihan PS, Webb CR, Alberts DS, Hamilton SR: Associations of Ki-ras proto-oncogene mutation and p53 gene overexpression in sporadic colorectal adenomas with demographic and clinicopathologic characteristics. Cancer Epidemiol Biomarkers Prev; 2006 Aug;15(8):1443-50
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Associations of Ki-ras proto-oncogene mutation and p53 gene overexpression in sporadic colorectal adenomas with demographic and clinicopathologic characteristics.
  • In colorectal tumorigenesis, Ki-ras proto-oncogene mutation often occurs early in the adenoma-adenocarcinoma sequence, whereas mutation of the p53 gene is associated with late progression to carcinoma.
  • We evaluated the relationship of demographic and clinicopathologic characteristics to Ki-ras mutation and p53 gene product overexpression in 1,093 baseline sporadic colorectal adenomas from 926 individuals enrolled in a phase III recurrence prevention trial.
  • Multivariate analysis found older age, rectal location, and villous histology to be independently associated with Ki-ras mutation.
  • Individuals with an advanced adenoma (>or=1 cm or high-grade dysplasia or villous histology) had a 4-fold higher likelihood of Ki-ras mutation [odds ratios (OR), 3.96; 95% confidence intervals (CI), 2.54-6.18].
  • Ki-ras mutations in codon 12 and of the G-to-A transition type were more frequent in older individuals, whereas G-to-T transversion was more frequent in rectal adenomas than in the colon.
  • Large adenoma size (>or=1 cm), high-grade dysplasia, and villous histology were independently associated with p53 overexpression, with the strongest association for advanced adenomas (OR, 7.20; 95% CI, 3.01-17.22).
  • Individuals with a Ki-ras mutated adenoma were more likely to overexpress p53 (OR, 2.46; 95% CI, 1.36-4.46), and 94.8% of adenomas with both alterations were classified as advanced (P <or= 0.0001).
  • Our large cross-sectional study supports the role of both Ki-ras and p53 in the progression of adenomas and shows that their molecular pathogenesis differs by anatomic location, age, and mucosal predisposition as evidenced by previous history of a polyp.

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Int J Cancer. 2002 Feb 20;97(6):823-7 [11857362.001]
  • [Cites] Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9433-8 [12093899.001]
  • [Cites] Annu Rev Genomics Hum Genet. 2002;3:101-28 [12142355.001]
  • [Cites] Carcinogenesis. 2003 Apr;24(4):703-10 [12727799.001]
  • [Cites] CA Cancer J Clin. 2004 Jan-Feb;54(1):8-29 [14974761.001]
  • [Cites] Proc R Soc Med. 1974 Jun;67(6 Pt 1):451-7 [4853754.001]
  • [Cites] Nature. 1987 May 28-Jun 3;327(6120):293-7 [3587348.001]
  • [Cites] Mutat Res. 1988 May;195(3):255-71 [3283542.001]
  • [Cites] N Engl J Med. 1988 Sep 1;319(9):525-32 [2841597.001]
  • [Cites] J Pathol. 1989 Mar;157(3):193-9 [2926561.001]
  • [Cites] Cell. 1990 Jun 1;61(5):759-67 [2188735.001]
  • [Cites] Proc Natl Acad Sci U S A. 1990 Oct;87(19):7555-9 [1699228.001]
  • [Cites] Am J Pathol. 1991 Apr;138(4):807-13 [1707233.001]
  • [Cites] Cancer Res. 1991 Aug 15;51(16):4436-42 [1868464.001]
  • [Cites] FASEB J. 1992 Mar;6(6):2302-10 [1544541.001]
  • [Cites] Int J Cancer. 1992 Mar 12;50(5):683-8 [1347513.001]
  • [Cites] Am J Clin Pathol. 1992 Feb;97(2):244-9 [1546693.001]
  • [Cites] Cancer Res. 1992 Apr 1;52(7):1974-80 [1551126.001]
  • [Cites] Science. 1992 Jan 10;255(5041):159 [1553541.001]
  • [Cites] Cancer Res. 1992 Jul 15;52(14):3965-71 [1319835.001]
  • [Cites] FASEB J. 1992 Jul;6(10):2783-90 [1321771.001]
  • [Cites] Gastroenterology. 1993 Jan;104(1):57-64 [8419262.001]
  • [Cites] Am J Pathol. 1993 Jan;142(1):87-93 [7678722.001]
  • [Cites] Gut. 1993 Mar;34(3):392-6 [8472989.001]
  • [Cites] Science. 1993 May 7;260(5109):816-9 [8484122.001]
  • [Cites] Int J Cancer. 1993 May 8;54(2):249-54 [8486427.001]
  • [Cites] Gut. 1993 May;34(5):621-4 [8504962.001]
  • [Cites] Anticancer Res. 1993 May-Jun;13(3):667-70 [8317895.001]
  • [Cites] Cell. 1993 Dec 17;75(6):1215-25 [8261515.001]
  • [Cites] Br J Cancer. 1994 Feb;69(2):367-71 [8297737.001]
  • [Cites] Jpn J Cancer Res. 1994 Feb;85(2):147-51 [8144396.001]
  • [Cites] Oncology. 1994 May-Jun;51(3):224-7 [7910956.001]
  • [Cites] Cancer Res. 1994 Sep 1;54(17):4798-804 [8062281.001]
  • [Cites] Cancer Detect Prev. 1994;18(3):187-95 [8076381.001]
  • [Cites] J Pathol. 1994 Jan;172(1):5-12 [7931827.001]
  • [Cites] Cancer. 1995 Feb 15;75(4):953-7 [7842415.001]
  • [Cites] Int J Cancer. 1995 Feb 20;64(1):47-51 [7665248.001]
  • [Cites] Diagn Mol Pathol. 1995 Sep;4(3):198-202 [7493139.001]
  • [Cites] Biotech Histochem. 1995 Mar;70(2):90-4 [7578594.001]
  • [Cites] Am J Surg. 1996 Jan;171(1):41-6 [8554149.001]
  • [Cites] Br J Cancer. 1996 Jul;74(1):99-108 [8679466.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 1996 Apr;5(4):285-91 [8722220.001]
  • [Cites] Hum Pathol. 1996 Oct;27(10):1042-9 [8892588.001]
  • [Cites] J Pathol. 1996 Dec;180(4):357-63 [9014854.001]
  • [Cites] Br J Cancer. 1997;75(3):341-7 [9020477.001]
  • [Cites] Cell. 1997 Feb 7;88(3):323-31 [9039259.001]
  • [Cites] Anticancer Res. 1996 Nov-Dec;16(6B):3839-44 [9042267.001]
  • [Cites] J Pathol. 1997 Mar;181(3):281-6 [9155713.001]
  • [Cites] Cancer Res. 1997 Jun 15;57(12):2485-92 [9192830.001]
  • [Cites] Dis Colon Rectum. 1997 Oct;40(10 Suppl):S16-22 [9378006.001]
  • [Cites] Scand J Gastroenterol. 1997 Oct;32(10):1035-41 [9361177.001]
  • [Cites] Cancer Res. 1998 Mar 15;58(6):1149-58 [9515799.001]
  • [Cites] J Natl Cancer Inst. 1998 May 6;90(9):675-84 [9586664.001]
  • [Cites] Am J Gastroenterol. 1998 Jun;93(6):980-4 [9647033.001]
  • [Cites] Anticancer Res. 1998 May-Jun;18(3A):1677-82 [9673389.001]
  • [Cites] Eur J Cancer. 1998 Mar;34(4):518-21 [9713302.001]
  • [Cites] Gut. 1999 Jun;44(6):826-33 [10323885.001]
  • [Cites] Clin Chem Lab Med. 1999 Jul;37(7):723-7 [10510729.001]
  • [Cites] J Natl Cancer Inst. 2005 Sep 21;97(18):1330-8 [16174854.001]
  • [Cites] Jpn J Cancer Res. 1991 Mar;82(3):245-9 [1708754.001]
  • [Cites] Cancer Res. 1999 Oct 15;59(20):5181-5 [10537295.001]
  • [Cites] Carcinogenesis. 2000 Mar;21(3):387-95 [10688859.001]
  • [Cites] Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2225-8 [10681434.001]
  • [Cites] N Engl J Med. 2000 Apr 20;342(16):1156-62 [10770980.001]
  • [Cites] Eur J Cancer Prev. 2000 Feb;9(1):41-7 [10777009.001]
  • [Cites] Dig Dis. 1999;17(4):225-9 [10754362.001]
  • [Cites] Gastroenterology. 2000 Jun;118(6):1045-50 [10833479.001]
  • [Cites] Eur J Cancer. 2000 May;36(8):1008-15 [10885605.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2000 Nov;9(11):1193-7 [11097226.001]
  • [Cites] Physiol Rev. 2001 Jul;81(3):1031-64 [11427691.001]
  • [Cites] Gastroenterology. 2001 Aug;121(2):302-9 [11487539.001]
  • [Cites] Gastroenterology. 2001 Sep;121(3):599-611 [11522744.001]
  • [Cites] Br J Cancer. 2001 Sep 1;85(5):692-6 [11531254.001]
  • [Cites] Mutat Res. 2001 Nov 1;483(1-2):73-81 [11600135.001]
  • [Cites] Cancer. 2002 Jan 1;94(1):219-27 [11815980.001]
  • [ErratumIn] Cancer Epidemiol Biomarkers Prev. 2006 Oct;15(10):2016. Rashid, Asif [added]
  • (PMID = 16896030.001).
  • [ISSN] 1055-9965
  • [Journal-full-title] Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
  • [ISO-abbreviation] Cancer Epidemiol. Biomarkers Prev.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P30 CA023074; United States / NCI NIH HHS / CA / P30 CA016672; United States / NCI NIH HHS / CA / CA16672; United States / NCI NIH HHS / CA / P01 CA041108; United States / NCI NIH HHS / CA / CA23074; United States / NCI NIH HHS / CA / CA41108
  • [Publication-type] Clinical Trial, Phase III; Comparative Study; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS430412; NLM/ PMC3547362
  •  go-up   go-down


37. Avanesian AA, Shcherbakov AM: [An experience with clinical endoscopy and argon-plasma coagulation for removal of large bowel polyps]. Vopr Onkol; 2005;51(5):592-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Polyp diameter ranged 1.0-1.9 cm (12 adenomas), 2-2.9 (18) or 3-5 cm (21).
  • Complete destruction of adenomas was achieved by 1-6 coagulations (mean - 1.4) performed at an interval of 3-4 weeks.
  • During follow-up (6-24 months), out of 40 patients with 51 polyps, histologically identifiable villous adenoma was detected in 3 (during 12 months).

  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • Hazardous Substances Data Bank. Argon, Elemental .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16756019.001).
  • [ISSN] 0507-3758
  • [Journal-full-title] Voprosy onkologii
  • [ISO-abbreviation] Vopr Onkol
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
  • [Chemical-registry-number] 67XQY1V3KH / Argon
  •  go-up   go-down


38. Jacobs ET, Martínez ME, Alberts DS, Ashbeck EL, Gapstur SM, Lance P, Thompson PA: Plasma insulin-like growth factor I is inversely associated with colorectal adenoma recurrence: a novel hypothesis. Cancer Epidemiol Biomarkers Prev; 2008 Feb;17(2):300-5
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Plasma insulin-like growth factor I is inversely associated with colorectal adenoma recurrence: a novel hypothesis.
  • Using cross-sectional and prospective study designs within the same cohort of men who had at least one adenoma at baseline, we investigated whether plasma IGF-I, IGF-I binding protein 1, and IGF-I binding protein 3 were associated with colorectal adenoma characteristics at baseline and whether their levels were related to odds for adenoma recurrence.
  • In cross-sectional analyses, plasma IGF-I was significantly positively associated with the presence of adenomas with any villous features (P = 0.04).
  • In contrast, IGF-I levels were inversely associated with odds of colorectal adenoma recurrence, with adjusted odds ratios (95% confidence interval) of 0.55 (0.29-1.01) and 0.49 (0.26-0.91) for the second and third tertiles of IGF-I, respectively, compared with the first tertile (P(trend) = 0.02).
  • The inverse association was stronger for advanced adenoma recurrence (P(trend) = 0.02) than for nonadvanced recurrence (P(trend) = 0.10).
  • These results suggest that, once an adenoma is removed, higher IGF-I levels reduce the odds of the formation of new lesions in the colorectum.
  • [MeSH-major] Adenoma / blood. Colorectal Neoplasms / blood. Insulin-Like Growth Factor I / metabolism. Neoplasm Recurrence, Local / blood

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • COS Scholar Universe. author profiles.
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18250342.001).
  • [ISSN] 1055-9965
  • [Journal-full-title] Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
  • [ISO-abbreviation] Cancer Epidemiol. Biomarkers Prev.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / 1K07CA10629-01A1; United States / NCI NIH HHS / CA / CA23074; United States / NCI NIH HHS / CA / CA41108; United States / NCI NIH HHS / CA / CA77145; United States / NCI NIH HHS / CA / CA95060
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Insulin-Like Growth Factor Binding Protein 1; 0 / Insulin-Like Growth Factor Binding Protein 3; 67763-96-6 / Insulin-Like Growth Factor I
  •  go-up   go-down


39. Herszényi L, Farinati F, Cardin R, István G, Molnár LD, Hritz I, De Paoli M, Plebani M, Tulassay Z: Tumor marker utility and prognostic relevance of cathepsin B, cathepsin L, urokinase-type plasminogen activator, plasminogen activator inhibitor type-1, CEA and CA 19-9 in colorectal cancer. BMC Cancer; 2008;8:194
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Protease, CEA and CA 19-9 serum or plasma levels were determined in 56 patients with colorectal cancer, 25 patients with ulcerative colitis, 26 patients with colorectal adenomas and 35 tumor-free control patients.
  • [MeSH-major] Adenoma, Villous / genetics. Biomarkers, Tumor / blood. Colorectal Neoplasms / genetics

  • Genetic Alliance. consumer health - Colorectal Cancer.
  • Genetic Alliance. consumer health - Colorectal cancer 1.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] World J Gastroenterol. 2006 Mar 7;12(9):1458-62 [16552821.001]
  • [Cites] Cancer. 2006 Mar 1;106(5):1026-35 [16435385.001]
  • [Cites] Biol Chem. 2006 Aug;387(8):1121-8 [16895483.001]
  • [Cites] BMC Cancer. 2006;6:211 [16916471.001]
  • [Cites] J Clin Oncol. 2006 Nov 20;24(33):5313-27 [17060676.001]
  • [Cites] Cancer Sci. 2006 May;97(5):395-9 [16630137.001]
  • [Cites] Cancer. 1999 Nov 1;86(9):1675-81 [10547539.001]
  • [Cites] Cancer. 1999 Dec 15;86(12):2602-11 [10594855.001]
  • [Cites] Ann Surg Oncol. 2000 Sep;7(8):617-23 [11005561.001]
  • [Cites] Int J Cancer. 2000 Sep 20;89(5):431-9 [11008205.001]
  • [Cites] Clin Chem. 2001 Apr;47(4):624-30 [11274010.001]
  • [Cites] Anticancer Res. 2000 Nov-Dec;20(6D):5195-8 [11326694.001]
  • [Cites] Clin Cancer Res. 2001 Sep;7(9):2757-64 [11555589.001]
  • [Cites] Int J Cancer. 2002 Oct 20;101(6):545-8 [12237895.001]
  • [Cites] Dis Colon Rectum. 2003 Nov;46(11):1538-44 [14605576.001]
  • [Cites] Cancer Res. 2004 Jan 15;64(2):659-64 [14744782.001]
  • [Cites] Cancer Lett. 2004 Mar 8;205(1):97-106 [15036666.001]
  • [Cites] Eur J Cancer. 2004 Jul;40(10):1610-6 [15196548.001]
  • [Cites] Ann Surg. 1967 Sep;166(3):420-7 [6039601.001]
  • [Cites] Cancer Res. 1983 Nov;43(11):5489-92 [6193872.001]
  • [Cites] Gut. 1986 Feb;27(2):117-22 [3949243.001]
  • [Cites] Cancer Res. 1987 Sep 1;47(17):4654-7 [3621160.001]
  • [Cites] Int J Biol Markers. 1988 Apr-Jun;3(2):101-6 [2977396.001]
  • [Cites] Semin Cancer Biol. 1990 Apr;1(2):137-52 [2103490.001]
  • [Cites] Cancer Res. 1991 Sep 15;51(18 Suppl):5054s-5059s [1884381.001]
  • [Cites] Gut. 1993 Jan;34(1):80-5 [8432457.001]
  • [Cites] Cancer Res. 1993 Apr 15;53(8):1788-93 [8467497.001]
  • [Cites] Cancer Lett. 1993 Jun 15;70(1-2):41-4 [8330299.001]
  • [Cites] Ann N Y Acad Sci. 1992 Dec 4;667:1-12 [1339240.001]
  • [Cites] Cancer Res. 1994 Jun 1;54(11):2900-7 [8187075.001]
  • [Cites] Gastroenterology. 1994 Nov;107(5):1449-56 [7926508.001]
  • [Cites] Cancer Lett. 1995 Sep 25;96(2):267-75 [7585467.001]
  • [Cites] Cancer. 1995 Aug 1;76(3):367-75 [8625115.001]
  • [Cites] Cancer. 1996 Mar 15;77(6):1035-43 [8635120.001]
  • [Cites] Carcinogenesis. 1996 Dec;17(12):2581-7 [9006092.001]
  • [Cites] Am J Gastroenterol. 1997 May;92(5):843-7 [9149198.001]
  • [Cites] Br J Cancer. 1997;75(12):1793-801 [9192984.001]
  • [Cites] Clin Exp Metastasis. 1997 Jul;15(4):418-25 [9219730.001]
  • [Cites] Clin Cancer Res. 1998 Jun;4(6):1511-6 [9626470.001]
  • [Cites] Br J Cancer. 1998 Nov;78(10):1346-9 [9823977.001]
  • [Cites] Dis Colon Rectum. 1999 Jul;42(7):921-9 [10411440.001]
  • [Cites] Cancer. 1999 Oct 1;86(7):1135-42 [10506696.001]
  • [Cites] J Surg Oncol. 2005 Mar 15;89(4):211-7 [15726622.001]
  • [Cites] Anticancer Res. 2004 Nov-Dec;24(6):4147-61 [15736466.001]
  • [Cites] J Cell Sci. 2005 Apr 1;118(Pt 7):1493-503 [15769846.001]
  • [Cites] Thromb Haemost. 2005 Apr;93(4):676-81 [15841311.001]
  • [Cites] Anticancer Res. 2005 Mar-Apr;25(2B):1377-84 [15865094.001]
  • [Cites] Cancer Lett. 2005 Jun 8;223(2):313-22 [15896466.001]
  • [Cites] Scand J Gastroenterol. 2005 Jul;40(7):783-93 [16109653.001]
  • [Cites] Br J Cancer. 2005 Oct 3;93(7):799-803 [16091756.001]
  • [Cites] J Clin Oncol. 2005 Dec 1;23(34):8706-12 [16314630.001]
  • [Cites] J Exp Ther Oncol. 2006;5(3):223-9 [16528972.001]
  • [Cites] Oncol Rep. 2007 Feb;17(2):361-7 [17203175.001]
  • [Cites] World J Gastroenterol. 2007 Feb 7;13(5):676-82 [17278189.001]
  • [Cites] Lung Cancer. 2007 Apr;56(1):43-50 [17207889.001]
  • [Cites] Head Neck. 2007 Apr;29(4):341-50 [17163465.001]
  • [Cites] Crit Rev Clin Lab Sci. 2007;44(2):179-201 [17364692.001]
  • [Cites] Eur J Cancer. 2007 Jun;43(9):1348-60 [17512720.001]
  • [Cites] J Cell Biochem. 2006 Apr 15;97(6):1230-40 [16315320.001]
  • (PMID = 18616803.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CA-19-9 Antigen; 0 / Carcinoembryonic Antigen; EC 3.4.- / Cathepsins; EC 3.4.21.73 / Urokinase-Type Plasminogen Activator; EC 3.4.22.- / Cysteine Endopeptidases; EC 3.4.22.1 / Cathepsin B; EC 3.4.22.15 / CTSL1 protein, human; EC 3.4.22.15 / Cathepsin L
  • [Other-IDs] NLM/ PMC2474636
  •  go-up   go-down


40. Khoo RE: Transanal excision of a rectal adenoma using single-access laparoscopic port. Dis Colon Rectum; 2010 Jul;53(7):1078-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Transanal excision of a rectal adenoma using single-access laparoscopic port.
  • Through this port, insufflation with gas maintained exposure of the surgical site, a 30-degree 5-mm camera, a grasper, and electrocautery were used to remove a large villous adenoma.
  • [MeSH-major] Adenoma, Villous / surgery. Colectomy / methods. Laparoscopes. Laparoscopy / methods. Rectal Neoplasms / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20551763.001).
  • [ISSN] 1530-0358
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


41. de Decker S, Bovy C, Deflandre J, Moonen M, Van Nes MC: Treatment of a nephrotic syndrome by endoscopic removal of a villous adenoma of the duodenum. Gastroenterol Clin Biol; 2010 Nov;34(11):625-8
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Treatment of a nephrotic syndrome by endoscopic removal of a villous adenoma of the duodenum.
  • We report the case of a patient diagnosed with a villous adenoma of the duodenum showing high degree dysplasia who developed a nephrotic syndrome (NS) due to a membranous nephropathy (MN), demonstrated by renal biopsy.
  • Only the endoscopic resection of the duodenal adenoma could control the NS.
  • [MeSH-major] Adenoma, Villous / surgery. Duodenal Neoplasms / surgery. Duodenoscopy. Nephrotic Syndrome / surgery

  • MedlinePlus Health Information. consumer health - Intestinal Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20850233.001).
  • [ISSN] 0399-8320
  • [Journal-full-title] Gastroentérologie clinique et biologique
  • [ISO-abbreviation] Gastroenterol. Clin. Biol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
  •  go-up   go-down


42. Kinney TP, Merel N, Hart J, Joseph L, Waxman I: Microsatellite analysis of sporadic flat and depressed lesions of the colon. Dig Dis Sci; 2005 Feb;50(2):327-30
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Of these specimens, eight were tubular adenomas, three were tubulovillous adenomas, and five were carcinomas in situ.
  • [MeSH-major] Adenoma, Villous / genetics. Colonic Neoplasms / genetics. Microsatellite Repeats

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Am Surg. 1992 Jun;58(6):383-6 [1596041.001]
  • [Cites] Endoscopy. 2001 Dec;33(12):1042-64 [11740647.001]
  • [Cites] Gut. 2002 Oct;51(4):550-5 [12235079.001]
  • [Cites] Dis Colon Rectum. 1994 May;37(5):450-5 [8181406.001]
  • [Cites] Surg Clin North Am. 2002 Oct;82(5):891-904 [12507199.001]
  • [Cites] Cancer Res. 2001 Mar 15;61(6):2676-83 [11289147.001]
  • [Cites] Cancer Res. 1998 Nov 15;58(22):5248-57 [9823339.001]
  • [Cites] Cancer Res. 1994 Jun 1;54(11):2841-4 [8187064.001]
  • [Cites] Cancer Res. 1994 Sep 1;54(17):4798-804 [8062281.001]
  • [Cites] Dis Colon Rectum. 1996 Feb;39(2):143-7 [8620779.001]
  • [Cites] Cancer. 1989 Sep 1;64(5):1138-46 [2758387.001]
  • [Cites] Gastrointest Endosc. 1995 Aug;42(2):109-13 [7590044.001]
  • [Cites] Gastrointest Endosc. 2002 Sep;56(3):333-8 [12196768.001]
  • [Cites] Am J Gastroenterol. 2003 Nov;98 (11):2543-9 [14638361.001]
  • [Cites] Br J Cancer. 2000 Jan;82(1):9-15 [10638959.001]
  • [Cites] Cancer. 1992 May 15;69(10):2406-10 [1568163.001]
  • [Cites] Anticancer Res. 1997 Jan-Feb;17(1B):737-42 [9066612.001]
  • [Cites] Dis Colon Rectum. 1985 Nov;28(11):847-51 [4053897.001]
  • [Cites] Gastroenterology. 2001 Jun;120(7):1657-65 [11375947.001]
  • [Cites] Gastrointest Endosc. 2002 Nov;56(5):663-71 [12397273.001]
  • [Cites] Gastrointest Endosc. 1995 Aug;42(2):184-7 [7590061.001]
  • [Cites] Dis Colon Rectum. 1991 Nov;34(11):981-6 [1935477.001]
  • [Cites] Gut. 1994 Sep;35(9):1258-61 [7959233.001]
  • (PMID = 15745095.001).
  • [ISSN] 0163-2116
  • [Journal-full-title] Digestive diseases and sciences
  • [ISO-abbreviation] Dig. Dis. Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


43. Targarona EM, Hernandez PM, Balague C, Martinez C, Hernández J, Pulido D, Berindoague R, Trias M: McKittrick-Wheelock syndrome treated by laparoscopy: report of 3 cases. Surg Laparosc Endosc Percutan Tech; 2008 Oct;18(5):536-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • AIM: To present 3 cases of secreting villous adenoma (McKittrick-Wheelock syndrome) successfully treated with laparoscopic surgery.
  • Owing to the extension and location of the adenomas, laparoscopic surgery (low anterior resection or procto-sigmoidectomy resection) was performed after medical treatment and endoscopic diagnosis.
  • CONCLUSIONS: When colonoscopic resection is not feasible in cases of secreting villous adenomas owing to their size or location, laparoscopic surgery in expert hands is a safe, effective, and complete option, further enhanced by the benefits of minimally invasion surgery.
  • [MeSH-major] Adenoma, Villous / surgery. Colorectal Neoplasms / surgery. Laparoscopy. Rectum / surgery. Water-Electrolyte Imbalance / etiology

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Fluid and Electrolyte Balance.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18936686.001).
  • [ISSN] 1534-4908
  • [Journal-full-title] Surgical laparoscopy, endoscopy & percutaneous techniques
  • [ISO-abbreviation] Surg Laparosc Endosc Percutan Tech
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


44. Kung JW, Levine MS, Glick SN, Lakhani P, Rubesin SE, Laufer I: Colorectal cancer: screening double-contrast barium enema examination in average-risk adults older than 50 years. Radiology; 2006 Sep;240(3):725-35
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The remaining 14 patients had a total of 21 neoplastic lesions 1 cm or larger, including 11 tubular adenomas, seven tubulovillous adenomas, one villous adenoma with marked dysplasia, and two cancers.

  • Genetic Alliance. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • Hazardous Substances Data Bank. Barium sulfate .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) RSNA, 2006.
  • (PMID = 16837671.001).
  • [ISSN] 0033-8419
  • [Journal-full-title] Radiology
  • [ISO-abbreviation] Radiology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 25BB7EKE2E / Barium Sulfate
  •  go-up   go-down


45. Cole BF, Baron JA, Sandler RS, Haile RW, Ahnen DJ, Bresalier RS, McKeown-Eyssen G, Summers RW, Rothstein RI, Burke CA, Snover DC, Church TR, Allen JI, Robertson DJ, Beck GJ, Bond JH, Byers T, Mandel JS, Mott LA, Pearson LH, Barry EL, Rees JR, Marcon N, Saibil F, Ueland PM, Greenberg ER, Polyp Prevention Study Group: Folic acid for the prevention of colorectal adenomas: a randomized clinical trial. JAMA; 2007 Jun 6;297(21):2351-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Folic acid for the prevention of colorectal adenomas: a randomized clinical trial.
  • OBJECTIVE: To assess the safety and efficacy of folic acid supplementation for preventing colorectal adenomas.
  • Participants included 1021 men and women with a recent history of colorectal adenomas and no previous invasive large intestine carcinoma.
  • MAIN OUTCOME MEASURES: The primary outcome measure was occurrence of at least 1 colorectal adenoma.
  • Secondary outcomes were the occurrence of advanced lesions (> or =25% villous features, high-grade dysplasia, size > or =1 cm, or invasive cancer) and adenoma multiplicity (0, 1-2, or > or =3 adenomas).
  • RESULTS: During the first 3 years, 987 participants (96.7%) underwent colonoscopic follow-up, and the incidence of at least 1 colorectal adenoma was 44.1% for folic acid (n = 221) and 42.4% for placebo (n = 206) (unadjusted risk ratio [RR], 1.04; 95% confidence interval [CI], 0.90-1.20; P = .58).
  • A total of 607 participants (59.5%) underwent a second follow-up, and the incidence of at least 1 colorectal adenoma was 41.9% for folic acid (n = 127) and 37.2% for placebo (n = 113) (unadjusted RR, 1.13; 95% CI, 0.93-1.37; P = .23); and incidence of at least 1 advanced lesion was 11.6% for folic acid (n = 35) and 6.9% for placebo (n = 21) (unadjusted RR, 1.67; 95% CI, 1.00-2.80; P = .05).
  • Folic acid was associated with higher risks of having 3 or more adenomas and of noncolorectal cancers.
  • CONCLUSIONS: Folic acid at 1 mg/d does not reduce colorectal adenoma risk.


46. Xu HX, Chen LD: Villous adenoma of extrahepatic bile duct: contrast-enhanced sonography findings. J Clin Ultrasound; 2008 Jan;36(1):39-41
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Villous adenoma of extrahepatic bile duct: contrast-enhanced sonography findings.
  • We report a case of villous adenoma in the extrahepatic bile duct that was successfully diagnosed with contrast-enhanced sonography (CEUS) before surgical resection.
  • Surgical resection was performed, and pathologic examination confirmed a villous adenoma of the bile duct epithelium with mild dysplasia.
  • [MeSH-major] Adenoma, Villous / ultrasonography. Bile Duct Neoplasms / ultrasonography. Bile Ducts, Extrahepatic / ultrasonography

  • MedlinePlus Health Information. consumer health - Bile Duct Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2007 Wiley Periodicals, Inc.
  • (PMID = 17565756.001).
  • [ISSN] 0091-2751
  • [Journal-full-title] Journal of clinical ultrasound : JCU
  • [ISO-abbreviation] J Clin Ultrasound
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
  •  go-up   go-down


47. Ghidirim G, Mişin I, Istrate V, Cazacu S: Endoscopic papillectomy into the treatment of neoplastic lesions of vater papilla. Curr Health Sci J; 2009 Apr;35(2):92-7
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Adenomas of the duodenal papilla are rare.
  • The frequency of malignant adenomas is 15-30%.
  • Villous adenoma is a premalignant lesion with the highest rate of transformation.
  • AIM: Evaluation of the efficacy and safety of endoscopic papillectomy for ampullary adenomas.
  • MATERIAL AND METHOD: 12 patients were selected (F:M, 5:7, age range 37 - 68 years) with ampullary adenoma, treated by endoscopic papillectomy.
  • Pathology examination has show: tubulo-villous adenoma (5 patients); villous adenoma (4 patients), tubular adenoma (2 cases), adenocarcinoma (one case).
  • CONCLUSION: Endoscopic papillectomy is a safe and well-tolerated alternative to surgical treatment of ampullary adenoma.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 24778815.001).
  • [ISSN] 2067-0656
  • [Journal-full-title] Current health sciences journal
  • [ISO-abbreviation] Curr Health Sci J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Romania
  • [Other-IDs] NLM/ PMC3945241
  • [Keywords] NOTNLM ; Vater papilla / ampullary adenoma / bleeding / endoscopic papillectomy / pancreatitis / sphyncterotomy
  •  go-up   go-down


48. Al-Enezi SA, Alsurayei SA, Ismail AE, Aly NY, Ismail WA, Abou-Bakr AA: Adenomatous colorectal polyps in patients referred for colonoscopy in a regional hospital in Kuwait. Saudi J Gastroenterol; 2010 Jul-Sep;16(3):188-93
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Histopathological examination of the most significant polyp in each patient revealed that 40 (74%) polyps were tubular adenomas (TAs); 11 (20%), tubulovillous (TV) adenomas; and 3 (6%), villous adenomas.
  • High-grade dysplasia was noticed in 4 (10%) adenomas.
  • Logistic regression analysis of some variables and their association with ACPs found that age (P < 0.001; OR, 1.9; CI, 1.5-2.3), history of adenoma (P=0.001; OR, 6.4; CI, .2.1-19.4) and being Kuwaitis (P=0.029; OR, 2.1; CI, 1.1-4.1) to be independently associated with ACPs.
  • CONCLUSION: The most common histological type of ACPs was tubular adenoma.

  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Gastroenterology. 1998 Jul;115(1):13-8 [9649453.001]
  • [Cites] Gastrointest Endosc. 2005 Apr;61(4):547-53 [15812407.001]
  • [Cites] Am J Gastroenterol. 2005 Dec;100(12):2749-55 [16393230.001]
  • [Cites] Asian Pac J Cancer Prev. 2005 Oct-Dec;6(4):537-40 [16436008.001]
  • [Cites] Gastrointest Endosc. 2006 Apr;63(4):546-57 [16564851.001]
  • [Cites] Gastrointest Endosc. 2006 Nov;64(5):751-9 [17055869.001]
  • [Cites] AJR Am J Roentgenol. 2007 Mar;188(3):619-21 [17312044.001]
  • [Cites] Gastrointest Endosc. 2007 Jun;65(7):1015-22 [17531636.001]
  • [Cites] World J Gastroenterol. 2007 Jul 28;13(28):3873-7 [17657845.001]
  • [Cites] Indian J Gastroenterol. 2007 May-Jun;26(3):127-9 [17704579.001]
  • [Cites] CA Cancer J Clin. 2008 Mar-Apr;58(2):71-96 [18287387.001]
  • [Cites] Ann Intern Med. 2008 Mar 18;148(6):419-26 [18347350.001]
  • [Cites] Gastroenterology. 2008 May;134(5):1311-5 [18471508.001]
  • [Cites] Gut. 2008 Aug;57(8):1166-76 [18628378.001]
  • [Cites] Jpn J Clin Oncol. 2009 Mar;39(3):196-8 [19233893.001]
  • [Cites] JAMA. 2000 Oct 18;284(15):1954-61 [11035892.001]
  • [Cites] N Engl J Med. 2000 Jul 20;343(3):162-8 [10900274.001]
  • [Cites] N Engl J Med. 2000 Jul 20;343(3):169-74 [10900275.001]
  • [Cites] Gastrointest Endosc. 2002 Apr;55(4):548-51 [11923770.001]
  • [Cites] Endoscopy. 2003 Jan;35(1):27-35 [12510223.001]
  • [Cites] J Formos Med Assoc. 2002 Oct;101(10):685-90 [12517041.001]
  • [Cites] Arch Intern Med. 2003 Feb 24;163(4):413-20 [12588199.001]
  • [Cites] Gastroenterology. 2003 Mar;124(3):608-14 [12612899.001]
  • [Cites] JAMA. 2003 Dec 10;290(22):2959-67 [14665657.001]
  • [Cites] Ann Intern Med. 2003 Dec 16;139(12):959-65 [14678915.001]
  • [Cites] Nutr Health. 2003;17(3):185-97 [14703151.001]
  • [Cites] Int J Cancer. 2004 May 1;109(5):777-81 [14999789.001]
  • [Cites] Am J Gastroenterol. 2004 Mar;99(3):472-7 [15056088.001]
  • [Cites] Cancer Detect Prev. 2004;28(4):260-8 [15350629.001]
  • [Cites] Am J Surg Pathol. 2004 Nov;28(11):1460-5 [15489649.001]
  • [Cites] N Engl J Med. 1988 Sep 1;319(9):533-7 [2841598.001]
  • [Cites] Gastroenterology. 1990 Feb;98(2):371-9 [2403953.001]
  • [Cites] Am J Gastroenterol. 1990 Aug;85(8):969-74 [2375325.001]
  • [Cites] Am J Gastroenterol. 1993 Jun;88(6):825-31 [8503374.001]
  • [Cites] Gastrointest Endosc. 1996 Aug;44(2):112-7 [8858314.001]
  • [Cites] N Engl J Med. 1997 Jan 2;336(1):8-12 [8970934.001]
  • [Cites] Br J Surg. 2005 Apr;92(4):478-81 [15609377.001]
  • [Cites] Lancet Oncol. 2005 Nov;6(11):871-6 [16257795.001]
  • (PMID = 20616414.001).
  • [ISSN] 1998-4049
  • [Journal-full-title] Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
  • [ISO-abbreviation] Saudi J Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Saudi Arabia
  • [Other-IDs] NLM/ PMC3003207
  •  go-up   go-down


49. Osunkoya AO, Epstein JI: Primary mucin-producing urothelial-type adenocarcinoma of prostate: report of 15 cases. Am J Surg Pathol; 2007 Sep;31(9):1323-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Prostatic urothelial-type adenocarcinoma arises through a process of glandular metaplasia of the prostatic urethral urothelium and subsequent in situ adenocarcinoma sometimes associated with villous adenoma.
  • Four men (26.7%) developed metastatic disease and 8 (53.3%) died of disease.
  • Multiple histologic patterns were observed including dissection of the stroma by mucin pools 15/15 (100%), villous features 7/15 (47%), necrosis 2/15 (13.3%), signet ring cells 3/15 (20%), perineural invasion 1/15 (6.7%), focal squamous differentiation 1/15 (6.7%), and a granulomatous inflammatory response 1/15 (6.7%).

  • MedlinePlus Health Information. consumer health - Prostate Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17721186.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CDX2 protein, human; 0 / CTNNB1 protein, human; 0 / Homeodomain Proteins; 0 / KRT20 protein, human; 0 / KRT7 protein, human; 0 / Keratin-20; 0 / Keratin-7; 0 / Mucins; 0 / beta Catenin; EC 3.1.3.2 / Acid Phosphatase; EC 3.1.3.2 / prostatic acid phosphatase; EC 3.1.3.48 / Protein Tyrosine Phosphatases; EC 3.4.21.77 / Prostate-Specific Antigen
  •  go-up   go-down


50. Parfitt JR, Driman DK: Survivin and hedgehog protein expression in serrated colorectal polyps: an immunohistochemical study. Hum Pathol; 2007 May;38(5):710-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Sessile serrated adenomas and traditional serrated adenomas are pathogenetically related to inhibition of apoptosis.
  • This study compares survivin and hedgehog protein expression in serrated polyps and tubulovillous adenomas.
  • Biopsies of sessile serrated adenomas (48) and traditional serrated adenomas (10) diagnosed during 2005 were retrieved from our files.
  • Biopsies of normal mucosa (10), hyperplastic polyps (14), and tubulovillous adenomas (22) were used for comparison.
  • Traditional serrated adenomas were also compared to sessile serrated adenomas with foci of cytological dysplasia (11 cases) with respect to MLH1 and p53 expression.
  • Sessile serrated adenomas showed high-grade nuclear and cytoplasmic expression of survivin at the bottom of crypts more frequently than tubulovillous adenomas (60% versus 18%, P = .001 [nuclear]; 54% versus 18%, P = .005 [cytoplasm]), the latter showing a top-heavy pattern of staining.
  • Survivin expression in hyperplastic polyps was similar to sessile serrated adenomas, being bottom-heavy, whereas traditional serrated adenomas showed diffuse staining throughout crypts.
  • Although traditional serrated adenomas showed high-grade expression of sonic hedgehog more frequently than tubulovillous adenomas (90% versus 18%; P < .001), sonic hedgehog, patched, and smoothened expression was low grade among normal mucosa, hyperplastic polyps, and sessile serrated adenomas.
  • All cytological dysplasias showed increased p53 expression within dysplastic foci, and MLH1 was also lost within dysplastic foci in 4 cases; traditional serrated adenomas showed intact MLH1 expression and minimal p53 expression throughout.
  • Survivin expression is localized to the bottom of crypts in sessile serrated adenomas and hyperplastic polyps, whereas tubulovillous adenomas show top-heavy expression.
  • Traditional serrated adenomas express survivin throughout crypts, suggesting intersection between the serrated and conventional adenoma-cancer pathways.
  • Sonic hedgehog up-regulation is characteristic of traditional serrated adenomas, distinguishing this entity from other colorectal polyps.
  • [MeSH-major] Adenoma, Villous / metabolism. Hedgehog Proteins / metabolism. Intestinal Polyps / metabolism. Microtubule-Associated Proteins / metabolism. Neoplasm Proteins / metabolism
  • [MeSH-minor] Adaptor Proteins, Signal Transducing. Adenoma / metabolism. Carrier Proteins / metabolism. Humans. Immunohistochemistry. Inhibitor of Apoptosis Proteins. Nuclear Proteins / metabolism. Tumor Suppressor Protein p53 / metabolism

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17391730.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Adaptor Proteins, Signal Transducing; 0 / BIRC5 protein, human; 0 / Carrier Proteins; 0 / Hedgehog Proteins; 0 / Inhibitor of Apoptosis Proteins; 0 / MLH1 protein, human; 0 / Microtubule-Associated Proteins; 0 / Neoplasm Proteins; 0 / Nuclear Proteins; 0 / Tumor Suppressor Protein p53
  •  go-up   go-down


51. Rex DK, Overhiser AJ, Chen SC, Cummings OW, Ulbright TM: Estimation of impact of American College of Radiology recommendations on CT colonography reporting for resection of high-risk adenoma findings. Am J Gastroenterol; 2009 Jan;104(1):149-53
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Estimation of impact of American College of Radiology recommendations on CT colonography reporting for resection of high-risk adenoma findings.
  • The aim of the study was to determine the impact of ACR recommendations on resection of high-risk adenoma findings using an endoscopic polyp/histology database.
  • METHODS: Excluding patients with inflammatory bowel disease (IBD) and polyposis, 10,034 patients underwent colonoscopy and 10,780 polyps were removed from 5,079 patients over a 5-year interval.
  • High-risk adenoma findings were defined as an advanced adenoma (> or =1 cm in size, high-grade dysplasia (HGD), or villous elements) or 3 or more adenomas of any size, per postpolypectomy surveillance recommendations.
  • RESULTS: A total of 5,079 patients (51%) had at least 1 polyp, 2,907 (29%) had at least 1 adenoma, and 1,001 (10%) had high-risk adenoma findings, of these, 293 (29%) had either 3 adenomas < or =5 mm in size (n=267) or an advanced adenoma < or =5 mm in size (or both) and no polyp of any histology > or =6 mm in size.
  • Of these patients 184 (18% of the patients with high-risk adenomas) had either 3 or more adenomas < or =9 mm in size (n=149) or an advanced adenoma < or =9 mm in size (or both findings).
  • There were 2,174 patients age > or =50 years with the primary indication of screening of whom 326 (15%) had high-risk adenoma findings.
  • Of these, 108 (33%) had either > or =3 adenomas < or =5 mm in size or an advanced adenoma < or =5 mm in size and no polyps > or =6 mm in size.
  • An additional 75 (23%) had no polyp > or =10 mm in size, 1 or 2 polyps 6-9 mm in size and > or =3 adenomas < or =9 mm in size or an advanced adenoma < or =9 mm in size.
  • CONCLUSIONS: If computed tomographic colonography (CTC) rather than colonoscopy were used in this population, assuming 100% sensitivity of CTC for polyps > or =6 mm and ACR interpretation recommendations, then 29% of all patients and 33% of screening patients age > or =50 years with high-risk adenoma findings would be interpreted as normal, and an additional 18-23% of these groups with high-risk adenoma findings, respectively, could have polypectomy delayed at least 3 years.
  • [MeSH-major] Adenoma / surgery. Colonic Neoplasms / surgery. Colonic Polyps / surgery. Colonography, Computed Tomographic. Colonoscopy

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • COS Scholar Universe. author profiles.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Am J Gastroenterol. 2009 Jun;104(6):1598-9; author reply 1600 [19436285.001]
  • [CommentIn] Am J Gastroenterol. 2009 Jun;104(6):1599-600; author reply 1600 [19436290.001]
  • [CommentIn] Gastroenterology. 2009 Jun;136(7):2395-6; discussion 2396-7 [19406132.001]
  • (PMID = 19098863.001).
  • [ISSN] 1572-0241
  • [Journal-full-title] The American journal of gastroenterology
  • [ISO-abbreviation] Am. J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


52. Segnan N, Senore C, Andreoni B, Azzoni A, Bisanti L, Cardelli A, Castiglione G, Crosta C, Ederle A, Fantin A, Ferrari A, Fracchia M, Ferrero F, Gasperoni S, Recchia S, Risio M, Rubeca T, Saracco G, Zappa M, SCORE3 Working Group-Italy: Comparing attendance and detection rate of colonoscopy with sigmoidoscopy and FIT for colorectal cancer screening. Gastroenterology; 2007 Jun;132(7):2304-12
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Screenees with "high-risk" distal polyps (villous component >20%, high-grade dysplasia, CRC, size >or=10 mm, >2 adenomas) at FS, or with positive FIT, were referred for TC.
  • FIT detected 2 patients with CRC (0.1%) and 21 with an advanced adenoma (1.1%).
  • [MeSH-minor] Adenoma / diagnosis. Disease Progression. Female. Humans. Male. Middle Aged. Patient Compliance. Patient Selection. Prevalence


53. Artifon EL, Sakai P, Baracat R, Moura EG: Endoscopic ampullectomy in a patient with a duodenal diverticulum. A challenging procedure. Rev Gastroenterol Mex; 2010;75(2):199-202
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Biopsy of the ampulla was positive for villous adenoma.
  • [MeSH-major] Adenoma, Villous / surgery. Ampulla of Vater / surgery. Common Bile Duct Neoplasms / surgery. Endoscopy, Digestive System

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20615792.001).
  • [ISSN] 0375-0906
  • [Journal-full-title] Revista de gastroenterología de México
  • [ISO-abbreviation] Rev Gastroenterol Mex
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Mexico
  •  go-up   go-down


54. Sato K, Tachibana H, Tsuzuki T, Ueda Y, Katsuda S: Prostatic ductal adenocarcinoma mimicking villous adenoma of the urethra. Virchows Arch; 2006 Nov;449(5):597-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Prostatic ductal adenocarcinoma mimicking villous adenoma of the urethra.

  • MedlinePlus Health Information. consumer health - Prostate Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Cancer. 1991 Apr 15;67(8):2118-24 [2004331.001]
  • [Cites] Cancer. 1973 Aug;32(2):402-9 [4124700.001]
  • [Cites] Cancer. 1967 Oct;20(10):1715-22 [4168340.001]
  • [Cites] Urology. 1994 May;43(5):737-42 [7513110.001]
  • (PMID = 16988838.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Germany
  •  go-up   go-down


55. Decker CJ: Transanal excision of rectal villous adenomas by laparoscopic methods. J Laparoendosc Adv Surg Tech A; 2005 Feb;15(1):23-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Transanal excision of rectal villous adenomas by laparoscopic methods.
  • Large villous adenomas of the rectum are not uncommon and will be encountered often by general and colorectal surgeons in their practices.
  • The approach to large adenomas can be via the colonoscope either transabdominally or transanally.
  • The method is simple and allows access to lesions up to 15 cm from the anal verge with a low incidence of complications, residual disease, and recurrence.
  • [MeSH-major] Adenoma, Villous / surgery. Laparoscopy / methods. Rectal Neoplasms / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15772472.001).
  • [ISSN] 1092-6429
  • [Journal-full-title] Journal of laparoendoscopic & advanced surgical techniques. Part A
  • [ISO-abbreviation] J Laparoendosc Adv Surg Tech A
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


56. Perçinel S, Savaş B, Ensari A, Kuzu I, Kuzu MA, Bektaş M, Cetinkaya H, Kurşun N: Mucins in the colorectal neoplastic spectrum with reference to conventional and serrated adenomas. Turk J Gastroenterol; 2007 Dec;18(4):230-8
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mucins in the colorectal neoplastic spectrum with reference to conventional and serrated adenomas.
  • BACKGROUND/AIMS: Alterations in expression of mucins and aberrant expression of various types of mucin genes were observed in colorectal adenomas and carcinomas, though their significance in neoplastic transformation of colorectal epithelium is yet to be determined.
  • The aim of this study was to determine expression of MUC1, MUC2, MUC5AC, and MUC6 through conventional adenoma-carcinoma sequence and polyps involved in the "serrated" pathway of the colorectum using tissue array technique.
  • METHODS: In this study, a total of 172 cases including 100 colorectal polyps [8 hyperplastic polyps, 10 sessile serrated adenomas, 19 tubular, 37 tubulovillous, and 26 villous adenomas], 16 adenomas with intramucosal carcinoma, 28 conventional colorectal cancers, and 28 normal mucosae were examined.
  • Sessile serrated adenomas exhibited the highest MUC5AC expression while adenomatous polyps showed an increase in MUC5AC expression in parallel with neoplastic progression (p<0.001).
  • Hyperplastic polyps seemed to lie between normal mucosa and sessile serrated adenomas in terms of mucin expression, suggesting that they are morphologically and histogenetically linked.
  • CONCLUSIONS: Upregulation of MUC1 and MUC6 through the adenoma-carcinoma sequence together with downregulation of MUC2 and MUC5AC at the neoplastic end of the spectrum seem to follow the steps of malignant transformation.
  • [MeSH-major] Adenoma / metabolism. Colonic Polyps / metabolism. Colorectal Neoplasms / metabolism. Mucins / metabolism


57. Cubuk R, Tasali N, Arslan G, Midi A, Manukyan MN, Guney S: A giant villous adenoma: case mimicking rectosigmoid malignancy; radiological survey to diagnosis. Prague Med Rep; 2010;111(1):76-81
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A giant villous adenoma: case mimicking rectosigmoid malignancy; radiological survey to diagnosis.
  • Villous adenomas are benign lesions, which are difficult to interpret because of their malignancy potential.
  • Usually, villous adenomas are asymptomatic although they may cause rectal bleeding like malignant tumours.
  • We present a case of giant villous adenoma to evaluate the contribution of its radiological features including double contrast barium enema, computed tomography and magnetic resonance imaging examinations for the differential diagnosis.
  • [MeSH-major] Adenoma, Villous / diagnosis. Colorectal Neoplasms / diagnosis

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20359441.001).
  • [ISSN] 1214-6994
  • [Journal-full-title] Prague medical report
  • [ISO-abbreviation] Prague Med Rep
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Czech Republic
  •  go-up   go-down


58. Qiu HZ, Lin GL, Xiao Y, Wu B: The use of posterior trans-sphincteric approach in surgery of the rectum: a Chinese 16-year experience. World J Surg; 2008 Aug;32(8):1776-82
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Data were collected retrospectively from clinical records of 102 patients with mid- to low-lying rectal neoplastic disease treated by a single surgeon using a posterior trans-sphincteric approach to the rectum at Peking Union Medical College Hospital, China, between August 1990 and August 2006.
  • Indications for surgery were rectal villous adenoma in 36, early rectal carcinoma in 43, advanced rectal carcinoma in 10, and rectal submucosal neoplastic disease in 13.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Lancet. 1991 Nov 9;338(8776):1166-9 [1682591.001]
  • [Cites] Zhonghua Wai Ke Za Zhi. 1993 Feb;31(2):124-6 [8223007.001]
  • [Cites] Prog Surg. 1974;13:66-97 [4445516.001]
  • [Cites] Dig Surg. 2005;22(1-2):86-90 [15849468.001]
  • [Cites] Proc R Soc Med. 1970;63 Suppl:91-4 [4947872.001]
  • [Cites] Ultrasound Med Biol. 2006 Apr;32(4):469-72 [16616592.001]
  • [Cites] Asian J Surg. 2006 Oct;29(4):227-32 [17098653.001]
  • [Cites] Zhonghua Wai Ke Za Zhi. 2007 Sep 1;45(17):1167-9 [18067707.001]
  • [Cites] Zhonghua Wei Chang Wai Ke Za Zhi. 2006 Mar;9(2):114-6 [16555147.001]
  • [Cites] Surg Annu. 1977;9:171-94 [882892.001]
  • [Cites] Dis Colon Rectum. 1987 Dec;30(12):939-41 [3691265.001]
  • [Cites] J Pediatr Surg. 1993 Jun;28(6):773-8 [8331501.001]
  • [Cites] Ann Surg. 1972 Nov;176(5):605-12 [5079820.001]
  • [Cites] Dig Surg. 2005;22(1-2):6-15 [15761225.001]
  • [Cites] Dis Colon Rectum. 1959 Sep-Oct;2:446-51 [14414212.001]
  • [Cites] Zhonghua Wai Ke Za Zhi. 1995 Mar;33(3):170-2 [7555388.001]
  • (PMID = 18560934.001).
  • [ISSN] 0364-2313
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


59. Khodadoostan M, Fatemi R, Maserat E, Hooshang A, Alizade M, Molaie M, Mashaiekhy R, Moaddab Y, Poor SY, Hashemy A, Zali MR: Clinical and pathological characteristics of colorectal polyps in Iranian population. East Afr J Public Health; 2010 Jun;7(2):157-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Adenomas were present in 727 (85%) cases, of these 411 (56% of adenomas) were left-sided and 316 (44% of adenomas) were right-sided.
  • Of them 354 were advance polyp (> 1 cm, villous type, high grade dysplasia).
  • CONCLUSION: This study has shown that a significant number of adenomas and carcinomas lie proximal to the splenic flexure.

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21413595.001).
  • [ISSN] 0856-8960
  • [Journal-full-title] East African journal of public health
  • [ISO-abbreviation] East Afr J Public Health
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Tanzania
  •  go-up   go-down


60. Valentí V, Hernández-Lizoáin JL, Gil A, Cervera M, Pastor C, Poveda I, Moncada R, Cienfuegos JA: [Secreting villous adenoma. Diagnosis and treatment]. Rev Esp Enferm Dig; 2005 Mar;97(3):215-6
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Secreting villous adenoma. Diagnosis and treatment].
  • [Transliterated title] Adenoma velloso hipersecretor de recto. Diagnóstico y tratamiento.
  • [MeSH-major] Adenoma, Villous / diagnosis. Colonic Neoplasms / diagnosis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentOn] Rev Esp Enferm Dig. 2003 Feb;95(2):159-60 [12760724.001]
  • (PMID = 15942989.001).
  • [ISSN] 1130-0108
  • [Journal-full-title] Revista española de enfermedades digestivas : organo oficial de la Sociedad Española de Patología Digestiva
  • [ISO-abbreviation] Rev Esp Enferm Dig
  • [Language] spa
  • [Publication-type] Case Reports; Comment; Letter
  • [Publication-country] Spain
  •  go-up   go-down


61. Lee SE, Park NH, Park IA, Kang SB, Lee HP: Tubulo-villous adenoma of the vagina. Gynecol Oncol; 2005 Feb;96(2):556-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tubulo-villous adenoma of the vagina.
  • BACKGROUND: Tubulo-villous adenomas are common in the colon and rectum, but extremely rare in the vagina.
  • As far as we know, only two cases of tubulo-villous adenoma have ever been reported.
  • We report the third case of enteric-type tubulo-villous adenoma of the vagina.
  • The tumor was excised and pathologically confirmed as a tubulo-villous adenoma.
  • CONCLUSION: Because some tubulo-villous adenomas in the colon and rectum can progress to the cancer, this case requires long-term follow-up to detect recurrence and malignant transformation.
  • [MeSH-major] Adenoma, Villous / pathology. Vaginal Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Vaginal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15661252.001).
  • [ISSN] 0090-8258
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 17
  •  go-up   go-down


62. Terhaar sive Droste JS, van Wanrooij RL, Morsink LM, van der Hulst RW, Craanen ME, Bartelsman JW, Meijer GA, Mulder CJ: [Diagnosis of colorectal tumours in daily clinical practice: comparison of colonoscopy and sigmoidoscopy]. Ned Tijdschr Geneeskd; 2009;153:A731
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Advanced neoplasm was defined as adenoma >or=10 mm in size, an adenoma with any villous features, or high-grade dysplasia or adenocarcinoma.

  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20003556.001).
  • [ISSN] 1876-8784
  • [Journal-full-title] Nederlands tijdschrift voor geneeskunde
  • [ISO-abbreviation] Ned Tijdschr Geneeskd
  • [Language] dut
  • [Publication-type] Comparative Study; English Abstract; Journal Article; Multicenter Study
  • [Publication-country] Netherlands
  •  go-up   go-down


63. Polydorides AD, Mukherjee B, Gruber SB, McKenna BJ, Appelman HD, Greenson JK: Adenoma-infiltrating lymphocytes (AILs) are a potential marker of hereditary nonpolyposis colorectal cancer. Am J Surg Pathol; 2008 Nov;32(11):1661-6
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenoma-infiltrating lymphocytes (AILs) are a potential marker of hereditary nonpolyposis colorectal cancer.
  • However, histologic features that are characteristic of and can perhaps distinguish colorectal adenomas in HNPCC patients from those occurring in the general population have not been previously reported.
  • We compared 16 adenomas endoscopically removed from patients with genetically proven HNPCC to 32 control adenomas, group-matched for patient age and sex, along with endoscopic size, shape, anatomic location, and presence of high-grade dysplasia.
  • Adenomas from HNPCC patients were more likely to contain high numbers of adenoma-infiltrating lymphocytes (AILs) with 12 of 16 (75%) adenomas having >or=5 AILs per high-power field (HPF) as opposed to 4 of 32 (12%) adenomas in the control group (P=0.00003).
  • HNPCC adenomas were also less likely to contain increased numbers of apoptotic bodies: 7 of 16 (44%) contained >or=5 apoptoses per HPF, compared with 27 of 36 (84%) control adenomas (P=0.006).
  • The presence of necrosis or serrated architecture, percent villous component, and numbers of mitotic figures per HPF did not differ significantly between the 2 groups.
  • Therefore, increased numbers of AILs and decreased numbers of apoptoses in colorectal adenomas are simple and inexpensive markers that raise the possibility of HNPCC.
  • [MeSH-major] Adenoma / immunology. Biomarkers, Tumor / immunology. Colorectal Neoplasms / immunology. Colorectal Neoplasms, Hereditary Nonpolyposis / immunology. Lymphocytes, Tumor-Infiltrating / immunology

  • Genetic Alliance. consumer health - Colorectal Cancer.
  • Genetic Alliance. consumer health - Hereditary Cancer.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Natl Cancer Inst. 1997 Dec 3;89(23):1758-62 [9392616.001]
  • [Cites] Semin Surg Oncol. 1995 Nov-Dec;11(6):406-10 [8607009.001]
  • [Cites] Am J Pathol. 1999 Jun;154(6):1805-13 [10362805.001]
  • [Cites] Am J Gastroenterol. 2005 Jan;100(1):139-43 [15654793.001]
  • [Cites] Oncogene. 2005 Apr 7;24(15):2525-35 [15735733.001]
  • [Cites] Am J Gastroenterol. 2005 May;100(5):1143-9 [15842591.001]
  • [Cites] Am J Gastroenterol. 2005 May;100(5):1150-3 [15842592.001]
  • [Cites] Gastroenterology. 2000 May;118(5):829-34 [10784581.001]
  • [Cites] Gut. 2000 Jul;47(1):37-42 [10861262.001]
  • [Cites] Virchows Arch. 2000 Jul;437(1):17-24 [10963375.001]
  • [Cites] Am J Pathol. 2001 Feb;158(2):527-35 [11159189.001]
  • [Cites] Gut. 2001 Mar;48(3):360-6 [11171826.001]
  • [Cites] Cancer. 2001 Jun 15;91(12):2417-22 [11413533.001]
  • [Cites] Gut. 2002 Feb;50(2):228-34 [11788565.001]
  • [Cites] Gut. 2002 Mar;50(3):382-6 [11839719.001]
  • [Cites] Am J Surg Pathol. 2003 May;27(5):563-70 [12717242.001]
  • [Cites] Am J Surg Pathol. 2003 Nov;27(11):1407-17 [14576473.001]
  • [Cites] Gastroenterology. 2004 Jan;126(1):42-8 [14699485.001]
  • [Cites] Gut. 1995 Mar;36(3):385-90 [7698698.001]
  • [Cites] J Pathol. 1995 May;176(1):37-44 [7616355.001]
  • [Cites] J Mol Diagn. 2005 May;7(2):160-70 [15858139.001]
  • [Cites] N Engl J Med. 2005 May 5;352(18):1851-60 [15872200.001]
  • [Cites] Mod Pathol. 2005 Aug;18(8):1095-101 [15731775.001]
  • [Cites] Dis Colon Rectum. 2006 Jan;49(1):80-93; discussion 94-5 [16284887.001]
  • [Cites] Hum Pathol. 2006 Jul;37(7):831-8 [16784982.001]
  • [Cites] Int J Colorectal Dis. 2006 Oct;21(7):632-41 [16511680.001]
  • [Cites] JAMA. 2006 Sep 27;296(12):1507-17 [17003399.001]
  • [Cites] Int J Colorectal Dis. 2007 Jul;22(7):739-48 [17109103.001]
  • [Cites] Gastroenterology. 2007 Oct;133(4):1093-8 [17919485.001]
  • [Cites] Dig Dis Sci. 2008 Jun;53(6):1660-8 [17999188.001]
  • [Cites] Anticancer Res. 1999 Jul-Aug;19(4B):3221-7 [10652615.001]
  • [Cites] In Vivo. 1995 May-Jun;9(3):173-6 [8562876.001]
  • [Cites] Cancer. 1996 Feb 15;77(4):627-34 [8616753.001]
  • [Cites] In Vivo. 1997 Sep-Oct;11(5):393-4 [9427041.001]
  • (PMID = 18753941.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / R01 CA081488
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ NIHMS417252; NLM/ PMC3500084
  •  go-up   go-down


64. van Rossum LG, van Rijn AF, Laheij RJ, van Oijen MG, Fockens P, Jansen JB, Verbeek AL, Dekker E: Cutoff value determines the performance of a semi-quantitative immunochemical faecal occult blood test in a colorectal cancer screening programme. Br J Cancer; 2009 Oct 20;101(8):1274-81
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The detection rate was the percentage of participants with CRC or advanced adenomas (>or=10 mm, >or=20% villous, high-grade dysplasia).
  • The number needed to scope (NNTScope) was the number of colonoscopies to be carried out to find one person with CRC or advanced adenomas.
  • The detection rate for advanced lesions (28 CRC and 161 with advanced adenomas) was 3.1% (95% confidence interval: 2.6-3.5%) and the NNTScope was 2.3.

  • Genetic Alliance. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Eur J Cancer Prev. 1997 Feb;6(1):38-43 [9161811.001]
  • [Cites] J Med Screen. 1996;3(2):66-71 [8849762.001]
  • [Cites] Kaohsiung J Med Sci. 2006 May;22(5):223-8 [16793557.001]
  • [Cites] Eur J Cancer Prev. 2006 Oct;15(5):384-90 [16912566.001]
  • [Cites] Int J Biol Markers. 2006 Jul-Sep;21(3):157-61 [17013797.001]
  • [Cites] N Engl J Med. 2006 Nov 2;355(18):1863-72 [17079760.001]
  • [Cites] J Epidemiol. 2006 Nov;16(6):240-8 [17085874.001]
  • [Cites] Gut. 2007 Feb;56(2):210-4 [16891354.001]
  • [Cites] Ann Intern Med. 2007 Feb 20;146(4):244-55 [17310048.001]
  • [Cites] Ann Oncol. 2007 Mar;18(3):581-92 [17287242.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2007 Mar;16(3):526-31 [17372248.001]
  • [Cites] Gastroenterology. 2007 Jun;132(7):2304-12 [17570205.001]
  • [Cites] Gastroenterology. 2008 Jul;135(1):82-90 [18482589.001]
  • [Cites] Br J Cancer. 2009 Jan 27;100(2):259-65 [19142185.001]
  • [Cites] Ann Intern Med. 2009 Feb 3;150(3):162-9 [19189905.001]
  • [Cites] Gut. 2000 Aug;47(2):251-5 [10896917.001]
  • [Cites] J Med Screen. 2002;9(3):99-103 [12370319.001]
  • [Cites] Am J Gastroenterol. 2003 Dec;98(12):2648-54 [14687811.001]
  • [Cites] Eur J Cancer Prev. 2004 Feb;13(1):19-26 [15075784.001]
  • [Cites] Gastroenterology. 2004 Jun;126(7):1674-80 [15188160.001]
  • [Cites] J Natl Cancer Inst. 2004 Oct 6;96(19):1420-5 [15467030.001]
  • [Cites] Methods Inf Med. 1987 Jan;26(1):53-8 [3561259.001]
  • [Cites] Am J Gastroenterol. 2005 Nov;100(11):2519-25 [16279909.001]
  • (PMID = 19755997.001).
  • [ISSN] 1532-1827
  • [Journal-full-title] British journal of cancer
  • [ISO-abbreviation] Br. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2768446
  •  go-up   go-down


65. Edden Y, Shussman N, Amir G, Pruss D, Rojansky N, Pikarsky AJ: Villous adenoma after appendiceal uterine transplantation. Int J Gynaecol Obstet; 2008 Jan;100(1):83-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Villous adenoma after appendiceal uterine transplantation.
  • [MeSH-major] Adenoma, Villous / complications. Appendiceal Neoplasms / complications. Appendix / pathology. Transplants / adverse effects

  • Genetic Alliance. consumer health - Transplantation.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17888436.001).
  • [ISSN] 0020-7292
  • [Journal-full-title] International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
  • [ISO-abbreviation] Int J Gynaecol Obstet
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


66. Shivaprakash HN, Jayashree K, Girish M: Villous adenoma: a rare tumor of vaginal vault. Indian J Pathol Microbiol; 2008 Apr-Jun;51(2):265-6
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Villous adenoma: a rare tumor of vaginal vault.
  • Villous adenomas are extremely rare tumors in the vagina and are indistinguishable from their colonic counterparts.
  • We present a case of villous adenoma of vaginal vault, a rare site of presentation in a 30-year-old female.
  • [MeSH-major] Adenoma, Villous / pathology. Vaginal Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Vaginal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18603704.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  •  go-up   go-down


67. Barry EL, Baron JA, Grau MV, Wallace K, Haile RW: K-ras mutations in incident sporadic colorectal adenomas. Cancer; 2006 Mar 1;106(5):1036-40
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] K-ras mutations in incident sporadic colorectal adenomas.
  • In the current study, the authors investigated associations with K-ras mutation in incident sporadic colorectal adenomas that occurred during a chemoprevention trial of calcium supplementation.
  • METHODS: K-ras genotyping was performed on 303 colorectal adenomas that were removed from 207 participants during the follow-up phase of the Calcium Polyp Prevention Study.
  • RESULTS: The adenomas analyzed had a mean estimated size of 0.5 cm, and 3.0% were identified with mutations (95% confidence interval [95% CI], 1.3-4.4%).
  • These mutations were more common in larger adenomas (risk ratio [RR], 12.7 for tumors that measured > 0.5 cm vs. < or = 0.5 cm; 95% CI, 2.7-59.7), in adenomas with more advanced histology (RR, 20.6 for tubulovillous/villous vs. tubular; 95% CI, 4.4-96.0), and in adenomas that were located in the rectum compared with the colon (RR, 8.4; 95% CI, 2.3-30.5).
  • CONCLUSIONS: Compared with previous studies, the current analysis was novel, because it focused on incident adenomas that were diagnosed within a few years of a previous "clean" colonoscopy.
  • The results provided evidence for a very low rate of K-ras mutation among these small, early adenomas and strong support for a role of K-ras mutations in adenoma progression.

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16456810.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / U01 CA046927; United States / NCI NIH HHS / CA / CA-046927
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  •  go-up   go-down


68. Anderson JC, Messina CR, Dakhllalah F, Abraham B, Alpern Z, Martin C, Hubbard PM, Grimson R, Shaw RD: Body mass index: a marker for significant colorectal neoplasia in a screening population. J Clin Gastroenterol; 2007 Mar;41(3):285-90
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Our outcome was the endoscopic detection of significant colorectal neoplasia which included adenocarcinoma, high-grade dysplasia, villous tissue, adenomas 1 cm or greater and multiple (>2) adenomas of any size.

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] J Clin Gastroenterol. 2007 Mar;41(3):229-30 [17426458.001]
  • (PMID = 17426468.001).
  • [ISSN] 0192-0790
  • [Journal-full-title] Journal of clinical gastroenterology
  • [ISO-abbreviation] J. Clin. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers
  •  go-up   go-down


69. Rubio CA, Nesi G, Messerini L, Zampi G: Serrated and microtubular colorectal adenomas in Italian patients. A 5-year survey. Anticancer Res; 2005 Mar-Apr;25(2B):1353-9
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Serrated and microtubular colorectal adenomas in Italian patients. A 5-year survey.
  • Colorectal adenomas from 1552 Italian patients were histologically classified into tubular (TAs), tubulo-villous (TVAs), villous (VAs), serrated (SAs) and microtubular (MTAs).
  • The purpose was to compare the results to those in 3135 colorectal adenomas from Swedish patients.
  • Of the 1552 adenomas, 827 (53%) were TAs, 352 (23%) TVAs, 196 (12%) VAs, 102 (7%), SAs and 14 (0.9%) MTAs.
  • The diameter of the largest section was used to define the size of the largest adenoma in individual patients.
  • SAs and MTAs are special adenoma phenotypes with particular morphological and cell proliferative attributes at variance from those of TAs, VAs or TVAs.
  • In the light of the present results, it is proposed that SAs and MTAs are included in future reports of colorectal adenomas in order to compare their frequency worldwide.
  • [MeSH-major] Adenoma / pathology. Colorectal Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15865091.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  •  go-up   go-down


70. Zorzi M, Baracco S, Fedato C, Grazzini G, Naldoni C, Sassoli dé Bianchi P, Senore C, Visioli CB, Cogo C: Screening for colorectal cancer in Italy: 2008 survey. Epidemiol Prev; 2010 Sep-Dec;34(5-6 Suppl 4):53-72
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Among the 665,264 subjects attending screening for the first time, the detection rate (DR) per 1,000 screened subjects was 2.7 for invasive cancer and 13.1 for advanced adenomas (AA, adenomas with a diameter ≥1 cm, with villous/ tubulo-villous type or with high-grade dysplasia).
  • The DR of cancer and adenomas increased with age and was higher among males.

  • Genetic Alliance. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21220837.001).
  • [ISSN] 1120-9763
  • [Journal-full-title] Epidemiologia e prevenzione
  • [ISO-abbreviation] Epidemiol Prev
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


71. Wang TD, Friedland S, Sahbaie P, Soetikno R, Hsiung PL, Liu JT, Crawford JM, Contag CH: Functional imaging of colonic mucosa with a fibered confocal microscope for real-time in vivo pathology. Clin Gastroenterol Hepatol; 2007 Nov;5(11):1300-5
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND & AIMS: Histologic interpretation of disease currently is performed with static images of excised tissues, and is limited by processing artifact, sampling error, and interpretive variability.
  • RESULTS: Normal mucosa showed circular crypts with uniform size, hyperplasia revealed proliferative glands with serrated lumens, and adenomas displayed distorted elongated glands.
  • For t greater than 5 seconds, high sensitivity, specificity, and accuracy was achieved using a discriminant function to evaluate the contrast ratio to distinguish normal from lesional mucosa (91%, 87%, and 89%, respectively; P < .001), hyperplasia from adenoma (97%, 96%, and 96%, respectively; P < .001), and tubular from villous adenoma (100%, 92%, and 93%, respectively; P < .001).

  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. FLUORESCEIN .
  • Hazardous Substances Data Bank. D&C Yellow No. 8 .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Biochem Pharmacol. 2002 Jan 1;63(1):81-8 [11754877.001]
  • [Cites] Endoscopy. 2007 Feb;39 Suppl 1:E145 [17611888.001]
  • [Cites] Appl Opt. 2002 Jan 1;41(1):182-92 [11900434.001]
  • [Cites] Br J Nutr. 2003 May;89(5):639-47 [12720584.001]
  • [Cites] Cancer Res. 2004 Sep 1;64(17):6247-51 [15342411.001]
  • [Cites] Gastroenterology. 2004 Sep;127(3):706-13 [15362025.001]
  • [Cites] Hum Pathol. 1983 Nov;14(11):931-68 [6629368.001]
  • [Cites] Hum Pathol. 1988 Feb;19(2):166-78 [3343032.001]
  • [Cites] Appl Opt. 2004 Nov 1;43(31):5763-71 [15540433.001]
  • [Cites] J Vasc Res. 2004 Sep-Oct;41(5):400-11 [15467299.001]
  • [Cites] Gastroenterology. 2005 Jun;128(7):2119-23 [15940642.001]
  • [Cites] Gastrointest Endosc. 2005 Nov;62(5):686-95 [16246680.001]
  • [Cites] Cancer Immunol Immunother. 2006 Jan;55(1):47-55 [15868166.001]
  • [Cites] Radiology. 2006 Feb;238(2):405-22 [16436809.001]
  • [Cites] J Pharm Sci. 2006 Jun;95(6):1393-401 [16625653.001]
  • [Cites] Clin Gastroenterol Hepatol. 2006 May;4(5):566-72 [16630761.001]
  • [Cites] Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):11003-8 [16835297.001]
  • [Cites] Clin Gastroenterol Hepatol. 2006 Aug;4(8):979-87 [16843068.001]
  • [Cites] Biochem Pharmacol. 2006 Sep 14;72(6):729-38 [16844096.001]
  • [Cites] Endoscopy. 2006 Sep;38(9):886-90 [16981104.001]
  • [Cites] Nature. 2006 Oct 19;443(7113):765 [17051200.001]
  • [Cites] Clin Gastroenterol Hepatol. 2006 Nov;4(11):1309-13 [17110299.001]
  • [Cites] Endoscopy. 2006 Nov;38(11):1110-4 [17111332.001]
  • [Cites] Neurosci Lett. 2007 Jan 3;411(1):1-5 [17110033.001]
  • [Cites] Am J Respir Crit Care Med. 2007 Jan 1;175(1):22-31 [17023733.001]
  • [Cites] Cell Tissue Res. 2007 Apr;328(1):77-84 [17165089.001]
  • [Cites] Gastrointest Endosc. 2007 Aug;66(2):398-99, discussion 400 [17521648.001]
  • [CommentIn] Clin Gastroenterol Hepatol. 2007 Nov;5(11):1259-60 [17936080.001]
  • (PMID = 17936692.001).
  • [ISSN] 1542-7714
  • [Journal-full-title] Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • [ISO-abbreviation] Clin. Gastroenterol. Hepatol.
  • [Language] ENG
  • [Grant] United States / NIDDK NIH HHS / DK / K08 DK067618-04; United States / NIDDK NIH HHS / DK / K08 DK067618; United States / NCI NIH HHS / CA / U54 CA105296; United States / NIDDK NIH HHS / DK / K08 DK067618-05; United States / NIDDK NIH HHS / DK / DK067618-04
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; TPY09G7XIR / Fluorescein
  • [Other-IDs] NLM/ NIHMS34014; NLM/ PMC2104519
  •  go-up   go-down


72. Korula A, Thomas M, Noronha J: Acquired perforating dermatosis: an innocuous lesion with possibly ominous implications. Cutis; 2010 Nov;86(5):242-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Acquired perforating dermatosis encompasses several specific disease entities occurring in adults that often have overlapping clinical and histologic features.
  • We describe a case of acquired perforating dermatosis presenting as the first symptom in a 64-year-old man who also was diagnosed to have mild obstructive jaundice due to a periampullary villous adenoma with high-grade dysplasia.
  • [MeSH-major] Adenoma, Villous / diagnosis. Duodenal Neoplasms / diagnosis. Skin Diseases / diagnosis

  • MedlinePlus Health Information. consumer health - Intestinal Cancer.
  • MedlinePlus Health Information. consumer health - Skin Conditions.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21214124.001).
  • [ISSN] 0011-4162
  • [Journal-full-title] Cutis
  • [ISO-abbreviation] Cutis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


73. Psofaki V, Kalogera C, Tzambouras N, Stephanou D, Tsianos E, Seferiadis K, Kolios G: Promoter methylation status of hMLH1, MGMT, and CDKN2A/p16 in colorectal adenomas. World J Gastroenterol; 2010 Jul 28;16(28):3553-60
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Promoter methylation status of hMLH1, MGMT, and CDKN2A/p16 in colorectal adenomas.
  • METHODS: DNA of healthy individuals, adenoma (tubular or villous/tubulovillous) patients, and colorectal carcinoma patients who underwent colonoscopy was used for assessing the prevalence of aberrant DNA methylation of human DNA mismatch repair gene mutator L homologue 1 (hMLH1), Cyclin-dependent kinase inhibitor 2A (CDKN2A/p16), and O-6-methylguanine DNA methyltransferase (MGMT), as well as their relation to MSI.
  • RESULTS: The frequency of promoter methylation for each locus increased in the sequence healthy tissue/adenoma/carcinoma.
  • MGMT and CDKN2A/p16 presented a statistically significant increase in promoter methylation between the less and more tumorigenic forms of colorectal adenomas (tubular vs tubullovillous and villous adenomas).
  • All patients with tubulovillous/villous adenomas, as well as all colorectal cancer patients, showed promoter methylation in at least one of the examined loci.
  • These findings suggest a potentially crucial role for methylation in the polyp/adenoma to cancer progression in colorectal carcinogenesis.
  • CONCLUSION: Methylation analysis of hMLH1, CDKN2A/p16, and MGMT revealed specific methylation profiles for tubular adenomas, tubulovillous/villous adenomas, and colorectal cancers, supporting the use of these alterations in assessment of colorectal tumorigenesis.
  • [MeSH-major] Adaptor Proteins, Signal Transducing / genetics. Adenoma / genetics. Colorectal Neoplasms / genetics. Cyclin-Dependent Kinase Inhibitor p16 / genetics. DNA Methylation / physiology. DNA Modification Methylases / genetics. DNA Repair Enzymes / genetics. Nuclear Proteins / genetics. Promoter Regions, Genetic / genetics. Tumor Suppressor Proteins / genetics
  • [MeSH-minor] Aged. CpG Islands / genetics. Disease Progression. Female. Humans. Male. Microsatellite Repeats / genetics. Middle Aged

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Clin Cancer Res. 2005 Feb 1;11(3):1203-9 [15709190.001]
  • [Cites] Hum Pathol. 2008 Jan;39(1):30-6 [17950780.001]
  • [Cites] J Clin Pathol. 1999 Jun;52(6):455-60 [10562815.001]
  • [Cites] Cancer Res. 2001 Feb 1;61(3):827-30 [11221863.001]
  • [Cites] Cancer Res. 2001 Feb 1;61(3):900-2 [11221878.001]
  • [Cites] Gastroenterology. 2001 Apr;120(5):1077-83 [11266371.001]
  • [Cites] Cancer Res. 2001 Jun 1;61(11):4545-9 [11389088.001]
  • [Cites] Am J Pathol. 2001 Sep;159(3):1129-35 [11549606.001]
  • [Cites] Eur J Cancer. 2000 Dec;36(18):2294-300 [11094302.001]
  • [Cites] Cancer Res. 2002 Feb 15;62(4):1166-70 [11861399.001]
  • [Cites] Am J Pathol. 2002 May;160(5):1823-30 [12000733.001]
  • [Cites] Oncogene. 2002 Aug 12;21(35):5427-40 [12154405.001]
  • [Cites] Annu Rev Genomics Hum Genet. 2002;3:101-28 [12142355.001]
  • [Cites] Cancer Res. 2003 Feb 15;63(4):787-92 [12591727.001]
  • [Cites] Am J Pathol. 2003 Mar;162(3):815-22 [12598316.001]
  • [Cites] Am J Pathol. 2003 Apr;162(4):1361-71 [12651628.001]
  • [Cites] Oncogene. 2003 Apr 17;22(15):2223-5 [12700658.001]
  • [Cites] Gut. 2004 Apr;53(4):573-80 [15016754.001]
  • [Cites] Cancer Biol Ther. 2004 Jan;3(1):73-8 [14726676.001]
  • [Cites] Lab Invest. 2004 Jul;84(7):884-93 [15122305.001]
  • [Cites] N Engl J Med. 1992 Mar 5;326(10):658-62 [1736104.001]
  • [Cites] Nature. 1993 Jun 10;363(6429):558-61 [8505985.001]
  • [Cites] Proc Natl Acad Sci U S A. 1996 Sep 3;93(18):9821-6 [8790415.001]
  • [Cites] Cancer Res. 1997 Mar 1;57(5):808-11 [9041175.001]
  • [Cites] Adv Cancer Res. 1998;72:141-96 [9338076.001]
  • [Cites] Cancer Res. 1997 Nov 1;57(21):4749-56 [9354436.001]
  • [Cites] Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):6870-5 [9618505.001]
  • [Cites] Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8698-702 [9671741.001]
  • [Cites] Cancer Res. 1998 Nov 15;58(22):5248-57 [9823339.001]
  • [Cites] Gastroenterology. 1999 May;116(5):1063-71 [10220498.001]
  • [Cites] J Clin Pathol. 1999 Jan;52(1):5-9 [10343605.001]
  • [Cites] Proc Natl Acad Sci U S A. 1999 Jul 20;96(15):8681-6 [10411935.001]
  • [Cites] Nat Rev Cancer. 2004 Dec;4(12):988-93 [15573120.001]
  • [Cites] Eur J Cancer. 2005 Feb;41(3):416-22 [15691642.001]
  • [Cites] Genes Chromosomes Cancer. 2006 Aug;45(8):781-9 [16708352.001]
  • [Cites] J Gastroenterol Hepatol. 2005 Dec;20(12):1920-6 [16336454.001]
  • (PMID = 20653064.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Adaptor Proteins, Signal Transducing; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / MLH1 protein, human; 0 / Nuclear Proteins; 0 / Tumor Suppressor Proteins; EC 2.1.1.- / DNA Modification Methylases; EC 2.1.1.63 / MGMT protein, human; EC 6.5.1.- / DNA Repair Enzymes
  • [Other-IDs] NLM/ PMC2909555
  •  go-up   go-down


74. Eisele R, Vogelsang E, Kraft K, Baumgarten U, Schick RR: Screening for colorectal lesions with high-resolution video colonoscopes in a German male average-risk population at 40 to 59 years of age. Z Gastroenterol; 2007 Sep;45(9):952-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • An advanced lesion was defined as an adenoma of at least 1 cm in diameter, a polyp with villous histological features or high-grade intraepithelial neoplasms or a cancer.
  • The question whether screening colonoscopy should therefore not only aim at detecting early colorectal cancer but also at identifying and removing precursor adenomas at younger ages clearly deserves further attention.

  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17874357.001).
  • [ISSN] 0044-2771
  • [Journal-full-title] Zeitschrift für Gastroenterologie
  • [ISO-abbreviation] Z Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  •  go-up   go-down


75. Zorzi M, Falcini F, Fedato C, Grazzini G, de' Bianchi PS, Senore C, Vettorazzi M, Visioli C, Zappa M: Screening for colorectal cancer in Italy: 2006 survey. Epidemiol Prev; 2008 Mar-Apr;32(2 Suppl 1):55-68
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • At first screening, the detection rate (DR) per 1,000 screened subjects was 3.1 and 14.6 for invasive cancer and advanced adenomas (AA--adenomas with a diameter > or =1 cm, with villous/tubulo-villous type or with high-grade dysplasia), respectively; the corresponding figures at repeat screening were 1.3 per thousand for cancer and 7.7 per thousand for AA.
  • The DR of cancer and adenomas increased with age and was higher among males; 25% of screen-detected cancers were in TNM stage III+.

  • Genetic Alliance. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18770995.001).
  • [ISSN] 1120-9763
  • [Journal-full-title] Epidemiologia e prevenzione
  • [ISO-abbreviation] Epidemiol Prev
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


76. Villanacci V: Diagnostic problems in the evaluation of colorectal adenomas. Am J Gastroenterol; 2008 Dec;103(12):3210-1; author reply 3211-2
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diagnostic problems in the evaluation of colorectal adenomas.
  • [MeSH-major] Adenoma / pathology. Colorectal Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentOn] "Should HGD or Degree of Villous Changes in Colon Polyps Be Reported?"
  • (PMID = 19086977.001).
  • [ISSN] 1572-0241
  • [Journal-full-title] The American journal of gastroenterology
  • [ISO-abbreviation] Am. J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] United States
  •  go-up   go-down


77. Dhamanaskar KP, Thurston W, Wilson SR: Transvaginal sonography as an adjunct to endorectal sonography in the staging of rectal cancer in women. AJR Am J Roentgenol; 2006 Jul;187(1):90-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Forty-nine of the women had rectal carcinoma; nine, tubulovillous adenoma; and two, gastrointestinal stromal tumor confirmed at surgical pathologic examination (n = 41) and biopsy before chemoradiation therapy (n = 19).
  • Four of the nine villous adenomas were overstaged as T1 on Tvs. Gastrointestinal stromal tumors manifested as intramural vascular masses.
  • [MeSH-minor] Adenoma, Villous / pathology. Adenoma, Villous / ultrasonography. Aged. Carcinoma / pathology. Carcinoma / ultrasonography. Female. Humans. Middle Aged. Sensitivity and Specificity. Vagina

  • Genetic Alliance. consumer health - Rectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16794161.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


78. Tanaka K, Toyoda H, Kadowaki S, Kosaka R, Shiraishi T, Imoto I, Shiku H, Adachi Y: Features of early gastric cancer and gastric adenoma by enhanced-magnification endoscopy. J Gastroenterol; 2006 Apr;41(4):332-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Features of early gastric cancer and gastric adenoma by enhanced-magnification endoscopy.
  • BACKGROUND: Changes to the mucosal surface of early gastric carcinomas and gastric adenomas as viewed by enhanced-magnification endoscopy with acetic acid have not been investigated thoroughly.
  • METHODS: Forty-seven consecutive patients with early gastric carcinomas or gastric adenomas underwent enhanced-magnification endoscopy following 1.5% acetic acid instillation.
  • RESULTS: Surface patterns of gastric tumors and the surrounding mucosa were classified into five types: type I, small round pits of uniform size and shape; type II, slit-like pits; type III, gyrus and villous patterns; type IV, irregular arrangements and sizes of pattern types I, II and III; type V, destructive patterns of types I, II and III.
  • Although all elevated adenomas showed type II or type III surface patterns, both depressed adenomas showed type IV.
  • [MeSH-major] Adenoma / pathology. Carcinoma / pathology. Endoscopy, Gastrointestinal / methods. Image Enhancement. Stomach Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] J Gastroenterol. 2006 Apr;41(4):397-8 [16741625.001]
  • [Cites] Endoscopy. 2004 Feb;36(2):165-9 [14765314.001]
  • [Cites] Gastrointest Endosc. 2004 Jan;59(1):15-21 [14722541.001]
  • [Cites] Am J Surg Pathol. 1995;19 Suppl 1:S37-43 [7762738.001]
  • [Cites] Gastrointest Endosc. 2001 May;53(6):559-65 [11323579.001]
  • [Cites] Gastrointest Endosc. 2003 Apr;57(4):498-504 [12665759.001]
  • [Cites] Gastrointest Endosc. 2002 Aug;56(2):279-84 [12145613.001]
  • [Cites] Endoscopy. 2003 May;35(5):437-45 [12701018.001]
  • [Cites] Endoscopy. 2002 Oct;34(10):772-7 [12244497.001]
  • [Cites] Endoscopy. 1978 Nov;10(4):269-74 [738222.001]
  • [Cites] Endoscopy. 2004 Dec;36(12):1080-4 [15578298.001]
  • [Cites] Aliment Pharmacol Ther. 2002 Mar;16 Suppl 1:3-15 [11849122.001]
  • (PMID = 16741612.001).
  • [ISSN] 0944-1174
  • [Journal-full-title] Journal of gastroenterology
  • [ISO-abbreviation] J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


79. Marderstein EL, Church JM: Classic "outlet" rectal bleeding does not require full colonoscopy to exclude significant pathology. Dis Colon Rectum; 2008 Feb;51(2):202-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Of the patients with outlet bleeding, only 47 (6.7 percent) had significant lesions on colonoscopy (adenomas >1 cm, villous adenomas, cancer in situ, or invasive cancer).
  • In 182 patients younger than aged 50 years with outlet bleeding, only 3 (1.6 percent) had adenomas >1 cm and no invasive cancers were detected.
  • [MeSH-minor] Adenoma / complications. Adenoma / epidemiology. Adenoma / pathology. Carcinoma in Situ / complications. Carcinoma in Situ / epidemiology. Carcinoma in Situ / pathology. Colonic Neoplasms / complications. Colonic Neoplasms / epidemiology. Colonic Neoplasms / pathology. Diagnosis, Differential. Follow-Up Studies. Humans. Incidence. Middle Aged. Neoplasm Invasiveness / pathology. Retrospective Studies. Severity of Illness Index. Time Factors

  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • MedlinePlus Health Information. consumer health - Gastrointestinal Bleeding.
  • MedlinePlus Health Information. consumer health - Rectal Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18172728.001).
  • [ISSN] 0012-3706
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


80. Meneghetti AT, Safadi B, Stewart L, Way LW: Local resection of ampullary tumors. J Gastrointest Surg; 2005 Dec;9(9):1300-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Preoperative biopsies (obtained in all patients) showed 18 adenomas, four adenomas with dysplasia, five adenomas with atypia, one adenoma with dysplasia and focal adenocarcinoma, and two tumors seen on endoscopy, whose biopsies showed only duodenal mucosa.
  • The final pathologic diagnosis was 23 villous adenomas, six adenocarcinomas, and one paraganglioma.
  • Among the 23 adenomas, three (13%) recurred (all as adenomas) at a mean of 3.2 years; in only one of these cases was the margin positive at the time of resection.
  • Ampullary adenomas can be resected locally with good results, but the recurrence rate was 13%, so endoscopic surveillance is indicated postoperatively.
  • No adenomas recurred as carcinomas, suggesting that local resection is appropriate for these tumors in the absence of dysplasia or atypia on preoperative biopsies.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Disease-Free Survival. Female. Humans. Male. Middle Aged

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Arch Surg. 1996 Apr;131(4):366-71 [8615720.001]
  • [Cites] Surgery. 2004 Nov;136(5):994-1002 [15523392.001]
  • [Cites] World J Surg. 2002 Jun;26(6):709-14 [12053224.001]
  • [Cites] Ann Surg. 1996 Nov;224(5):621-7 [8916877.001]
  • [Cites] World J Surg. 1996 Jul-Aug;20(6):707-12 [8662157.001]
  • [Cites] Gastrointest Endosc. 2002 Aug;56(2):239-43 [12145603.001]
  • [Cites] Surg Gynecol Obstet. 1993 Oct;177(4):366-70 [8211580.001]
  • [Cites] Ann Surg. 1989 May;209(5):593-8; discussion 598-9 [2650645.001]
  • [Cites] Endoscopy. 1981 Jul;13(4):154-6 [7250083.001]
  • [Cites] Surg Endosc. 1987;1(1):5-10 [3504051.001]
  • [Cites] Surgery. 1995 Mar;117(3):247-53 [7878528.001]
  • [Cites] J Clin Gastroenterol. 1996 Apr;22(3):237-41 [8724267.001]
  • [Cites] Am Surg. 1990 Apr;56(4):214-7 [2194412.001]
  • [Cites] Ann Oncol. 1999 Oct;10(10):1227-31 [10586341.001]
  • [Cites] Endoscopy. 2003 May;35(5):402-6 [12701011.001]
  • [Cites] Gastrointest Endosc. 2004 Feb;59(2):225-32 [14745396.001]
  • [Cites] Arch Surg. 1991 Mar;126(3):353-7 [1998478.001]
  • [Cites] Surgery. 2000 Jun;127(6):628-33 [10840357.001]
  • [Cites] Ann Surg. 1986 Mar;203(3):301-6 [3954483.001]
  • [Cites] J Gastrointest Surg. 2000 Jan-Feb;4(1):13-21, discussion 22-3 [10631358.001]
  • [Cites] Hum Pathol. 1985 Mar;16(3):305-10 [3972407.001]
  • [Cites] Gut. 1981 Dec;22(12):1031-4 [7319287.001]
  • [Cites] Arch Surg. 1999 May;134(5):526-32 [10323425.001]
  • [Cites] Gastrointest Endosc. 1993 Mar-Apr;39(2):127-31 [8495831.001]
  • [Cites] Endoscopy. 2005 May;37(5):444-8 [15844023.001]
  • (PMID = 16332486.001).
  • [ISSN] 1091-255X
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


81. Rudraraju M, Osowo AT, Singh V, Carey EJ: Do patients need more frequent colonoscopic surveillance after liver transplantation? Transplant Proc; 2008 Jun;40(5):1522-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The aim of our study was to determine the risk of development of colon polyps with advanced features and colon carcinoma in liver transplant (LT) recipients when compared to individuals with chronic liver disease (CLD) and individuals without liver disease.
  • METHODS: Case-control analyses of 82 LT recipients who underwent posttransplant colonoscopy, matched for age, gender, and year of colonoscopy, were compared to 82 patients with chronic liver disease and 82 patients without liver disease undergoing screening colonoscopy.
  • Incidence of advanced adenomas (polyps >1 cm, high-grade dysplasia, villous histology) and colon carcinoma was documented.
  • Six patients (7.3%) of the LT group, 3 patients (3.6%) of the chronic liver disease group, and 1 patient (1.2%) of the no-liver-disease group had the outcome of interest, but the P value was not significant.


82. Piana S, Asioli S, Foroni M: Oncocytic adenocarcinoma of the rectum arising on a villous adenoma with oncocytic features. Virchows Arch; 2006 Feb;448(2):228-31
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Oncocytic adenocarcinoma of the rectum arising on a villous adenoma with oncocytic features.
  • We describe a case of oncocytic adenocarcinoma of the rectum, associated with a villous adenoma, arising on a 66-year-old man.
  • Superficially, a villous adenoma with high-grade dysplasia was evident; adenomatous cells showed focal eosinophilic changes, consisting of a large granular cytoplasm, an oval atypical nucleus, and a prominent nucleolus.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma, Villous / pathology. Rectal Neoplasms / pathology

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Hum Pathol. 1999 Aug;30(8):926-33 [10452505.001]
  • [Cites] Cell. 1993 Aug 27;74(4):597-608 [8358789.001]
  • [Cites] Virchows Arch. 1998 Jul;433(1):5-12 [9692819.001]
  • [Cites] Semin Diagn Pathol. 1999 May;16(2):98-104 [10452575.001]
  • [Cites] Virchows Arch. 2000 Aug;437(2):107-15 [10993269.001]
  • [Cites] Virchows Arch. 2000 Jun;436(6):602-7 [10917176.001]
  • [Cites] Int J Surg Pathol. 2005 Jan;13(1):29-35 [15735852.001]
  • [Cites] Semin Diagn Pathol. 1999 May;16(2):82-90 [10452573.001]
  • [Cites] Pathol Oncol Res. 1999;5(4):273-9 [10607921.001]
  • [Cites] Science. 1998 Aug 28;281(5381):1309-12 [9721092.001]
  • [Cites] J Clin Pathol. 1995 Jan;48(1):46-52 [7706518.001]
  • [Cites] Hum Pathol. 1996 Oct;27(10):1071-6 [8892593.001]
  • [Cites] Virchows Arch. 2003 Oct;443(4):579-82 [12955503.001]
  • [Cites] J Pathol. 1994 Apr;172(4):337-42 [8207614.001]
  • [Cites] Am J Surg Pathol. 2002 Apr;26(4):458-65 [11914623.001]
  • [Cites] Am J Surg Pathol. 1994 Oct;18(10):1054-64 [7522412.001]
  • [Cites] Semin Diagn Pathol. 1999 May;16(2):146-61 [10452580.001]
  • [Cites] Hum Pathol. 1996 Feb;27(2):102-10 [8617450.001]
  • [Cites] Virchows Arch Pathol Anat Physiol Klin Med. 1962;335:452-83 [13904234.001]
  • [Cites] Semin Diagn Pathol. 1999 May;16(2):126-34 [10452578.001]
  • [Cites] Hum Pathol. 1989 Jul;20(7):696-700 [2661411.001]
  • [Cites] Virchows Arch. 1997 Aug;431(2):111-7 [9293892.001]
  • [Cites] Virchows Arch. 1997 Feb;430(2):125-30 [9083515.001]
  • [Cites] Semin Diagn Pathol. 1999 May;16(2):117-25 [10452577.001]
  • [Cites] J Pathol. 1993 Apr;169(4):431-7 [8501540.001]
  • [Cites] Semin Diagn Pathol. 1999 May;16(2):135-45 [10452579.001]
  • (PMID = 16450120.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / CDX2 Transcription Factor; 0 / CDX2 protein, human; 0 / Carcinoembryonic Antigen; 0 / Homeodomain Proteins; 0 / Keratin-20; 0 / Ki-67 Antigen; 0 / Tumor Suppressor Protein p53
  •  go-up   go-down


83. Schiessel R, Novi G, Holzer B, Rosen HR, Renner K, Hölbling N, Feil W, Urban M: Technique and long-term results of intersphincteric resection for low rectal cancer. Dis Colon Rectum; 2005 Oct;48(10):1858-65; discussion 1865-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: One hundred seventeen patients had rectal cancers, two had dysplastic villous adenomas, and two had carcinoid tumors.
  • [MeSH-major] Adenocarcinoma / surgery. Adenoma, Villous / surgery. Anal Canal / surgery. Carcinoid Tumor / surgery. Colectomy / methods. Rectal Neoplasms / surgery

  • Genetic Alliance. consumer health - Rectal Cancer.
  • MedlinePlus Health Information. consumer health - Carcinoid Tumors.
  • Hazardous Substances Data Bank. FLUOROURACIL .
  • Hazardous Substances Data Bank. LEUCOVORIN .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16086223.001).
  • [ISSN] 0012-3706
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil
  •  go-up   go-down


84. Nguyen AV, Albers CG, Holcombe RF: Differentiation of tubular and villous adenomas based on Wnt pathway-related gene expression profiles. Int J Mol Med; 2010 Jul;26(1):121-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Differentiation of tubular and villous adenomas based on Wnt pathway-related gene expression profiles.
  • This study was undertaken to define whether differences in the expression of Wnt pathway components are present between normal colonic mucosa, early (tubular) adenomas and villous adenomas which have a higher malignant potential.
  • Normal mucosa, tubular adenomas and villous adenomas were obtained from twelve patients.
  • Fifteen Wnt pathway-related genes showed differential expression between villous adenomas and normal mucosa and villous and tubular adenomas at a significance level of p<0.01.
  • Genes involved in canonical Wnt (beta-catenin) signaling with increased expression in villous adenomas included wnt1, fz2, csnk2A2, pygo2, pygo1, frat2 and myc, the latter confirmed by qRT-PCR and IHC.
  • Myc protein expression was confined primarily to stromal components of villous adenomas.
  • Genes involved in non-canonical Wnt signaling with increased expression in villous adenomas included rho-u, daam1, damm2, cxxc4 and nlk.
  • Successive increases in the expression of ctnnb1 (beta-catenin) from normal to tubular adenomas to villous adenomas was seen.
  • The Wnt pathway gene expression profile can differentiate between tubular and villous adenomas.
  • These data suggest that Wnt signaling regulation changes during the progression from normal mucosa to tubular adenomas to villous adenomas.
  • Expression of Myc in adenoma stroma suggests a dynamic signaling network within adenomas between mucosal and stromal elements.
  • Inhibition of the Wnt pathway may provide a novel approach for cancer prevention in patients with benign tubular adenomas.
  • [MeSH-major] Adenoma / genetics. Adenoma, Villous / genetics. Colonic Neoplasms / genetics. Gene Expression Profiling. Signal Transduction / genetics

  • COS Scholar Universe. author profiles.
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20514431.001).
  • [ISSN] 1791-244X
  • [Journal-full-title] International journal of molecular medicine
  • [ISO-abbreviation] Int. J. Mol. Med.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA82450
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Wnt Proteins
  •  go-up   go-down


85. Soreide K, Buter TC, Janssen EA, van Diermen B, Baak JP: A monotonous population of elongated cells (MPECs) in colorectal adenoma indicates a high risk of metachronous cancer. Am J Surg Pathol; 2006 Sep;30(9):1120-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A monotonous population of elongated cells (MPECs) in colorectal adenoma indicates a high risk of metachronous cancer.
  • We evaluated the prognostic value of classical clinicopathologic features and a monotonous population of elongated cells (MPECs) in colorectal adenomas from 171 consecutively selected population-based patients with long-term follow-up.
  • Ten of 171 adenomas (5.8%) developed metachronous CRC (defined as >24 mo interval and >5 cm from the index adenoma to the cancer).
  • Median follow-up of adenomas with metachronous CRC was 68.4 and without cancer 149.7 months (range: 25 to 192 and 25 to 256, respectively).
  • The most prognostic classical features were the localization of the marker adenoma as proximal (ie, in the cecum through transverse colon) versus distal from the transverse colon [P=0.0003, hazard ratio (HR)=8] and the number of polyps found during colonoscopy (<or=2 vs.>2, P=0.002, HR=6).
  • Of the 171 adenomas, 50 (29%) had MPECs, of which 9 (18%) patients developed metachronous CRC at follow-up, contrasting 1/121 (0.8%) without MPECs (P=0.0003, HR=23).
  • MPECs occurred in both low-grade and high-grade dysplasia, and in tubular and (tubulo) villous adenomas.
  • Adenomas proximally located had additional value but only if they were MPEC positive (which only occurred in 5 adenomas, 3 of which (60%) developed cancer).
  • Having more than 2 polyps also had additional prognostic value but only in MPEC-negative adenomas [10 cases; 1 (10%) developed cancer].
  • Thus, colorectal adenomas with subsequent metachronous cancer development can be identified more accurately with MPECs than with classical prognostic factors.
  • [MeSH-major] Adenoma / pathology. Colorectal Neoplasms / pathology. Neoplasms, Second Primary / pathology

  • Genetic Alliance. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16931957.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


86. Jotautas V, Strupas K, Poskus E, Seinin D: [Treatment of rectal tumors with transanal endoscopic microsurgery]. Medicina (Kaunas); 2005;41(6):470-6
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • MATERIALS AND METHODS: The patients who had rectal adenomas and low-risk T1 carcinomas of good or moderate differentiation, with no lymphatic and vascular invasion were selected for surgery.
  • Overall 25 (52.1%) carcinomas and 23 (47.9%) adenomas were removed.
  • Twenty-six patients were followed up for 3-17 months after operation: 17 after removal of cancer and 9 after removal of adenoma.
  • One (2.1%) recurrence of a tubulovillous adenoma was diagnosed.
  • CONCLUSIONS: Initial results of transanal endoscopic microsurgery obtained while treating rectal adenomas and low-risk T1 cancers are promising.
  • [MeSH-major] Adenoma / surgery. Carcinoma / surgery. Proctoscopy / methods. Rectal Neoplasms / surgery
  • [MeSH-minor] Adenoma, Villous / pathology. Adenoma, Villous / radiotherapy. Adenoma, Villous / surgery. Adult. Aged. Aged, 80 and over. Biopsy. Combined Modality Therapy. Data Interpretation, Statistical. Female. Humans. Male. Microsurgery. Middle Aged. Minimally Invasive Surgical Procedures. Neoplasm Staging. Radiotherapy Dosage. Radiotherapy, Adjuvant. Rectum / pathology. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15998984.001).
  • [ISSN] 1648-9144
  • [Journal-full-title] Medicina (Kaunas, Lithuania)
  • [ISO-abbreviation] Medicina (Kaunas)
  • [Language] lit
  • [Publication-type] Comparative Study; English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] Lithuania
  •  go-up   go-down


87. Rubio CA, Stemme S, Jaramillo E, Lindblom A: Hyperplastic polyposis coli syndrome and colorectal carcinoma. Endoscopy; 2006 Mar;38(3):266-70
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Other colorectal lesions were found as follows: two patients each had one mixed polyp; there were 15 serrated adenomas in eight patients; and there were 30 tubular, tubulovillous, or villous adenomas in eight patients.
  • Of the four villous adenomas, three were associated with a CRC, but only one of the 15 serrated adenomas was associated with a CRC.
  • [MeSH-minor] Adenoma / pathology. Aged. Colonic Neoplasms / pathology. Female. Humans. Hyperplasia. Male. Middle Aged

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16528654.001).
  • [ISSN] 0013-726X
  • [Journal-full-title] Endoscopy
  • [ISO-abbreviation] Endoscopy
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 35
  •  go-up   go-down


88. Tang H, Guo Q, Zhang C, Zhu J, Yang H, Zou YL, Yan Y, Hong D, Sou T, Yan XM: Identification of an intermediate signature that marks the initial phases of the colorectal adenoma-carcinoma transition. Int J Mol Med; 2010 Nov;26(5):631-41
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Identification of an intermediate signature that marks the initial phases of the colorectal adenoma-carcinoma transition.
  • The colorectal adenoma-carcinoma sequence describes the stepwise progression from normal to dysplastic epithelium and then to carcinoma.
  • Only a small proportion of colorectal adenomas (CRAs) progress to colorectal carcinomas (CRCs).
  • Endoscopic intervention is currently being used on patients with high grade dysplasia CRAs, with diameters of >1 cm, or villous components of >25% who are at higher risk than other CRA sufferers.
  • [MeSH-major] Adenoma / genetics. Biomarkers, Tumor / genetics. Carcinoma / genetics. Colorectal Neoplasms / genetics
  • [MeSH-minor] Carcinoma, Transitional Cell / pathology. Cell Line, Tumor. Disease Progression. Gene Expression Profiling. Humans. Immunohistochemistry. Neoplasm Staging. Reverse Transcriptase Polymerase Chain Reaction

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20878084.001).
  • [ISSN] 1791-244X
  • [Journal-full-title] International journal of molecular medicine
  • [ISO-abbreviation] Int. J. Mol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down


89. van Rossum LG, van Rijn AF, Laheij RJ, van Oijen MG, Fockens P, van Krieken HH, Verbeek AL, Jansen JB, Dekker E: Random comparison of guaiac and immunochemical fecal occult blood tests for colorectal cancer in a screening population. Gastroenterology; 2008 Jul;135(1):82-90
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Advanced adenomas were defined as >or=10 mm, high-grade dysplasia, or >or=20% villous component.
  • Cancer and advanced adenomas were found, respectively, in 11 and 48 of G-FOBTs and in 24 and 121 of I-FOBTs.
  • Differences in positive predictive value for cancer and advanced adenomas and cancer were, respectively, 2.1% (P = .4) and -3.6% (P = .5).
  • However, participation and detection rates for advanced adenomas and cancer were significantly higher for I-FOBT.
  • G-FOBT significantly underestimates the prevalence of advanced adenomas and cancer in the screening population compared with I-FOBT.
  • [MeSH-major] Adenoma / diagnosis. Colorectal Neoplasms / diagnosis. Guaiac. Immunohistochemistry. Mass Screening / methods. Occult Blood

  • Genetic Alliance. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • Hazardous Substances Data Bank. GUM GUAIAC .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Nat Clin Pract Gastroenterol Hepatol. 2009 Mar;6(3):140-1 [19174764.001]
  • (PMID = 18482589.001).
  • [ISSN] 1528-0012
  • [Journal-full-title] Gastroenterology
  • [ISO-abbreviation] Gastroenterology
  • [Language] eng
  • [Databank-accession-numbers] ISRCTN/ ISRCTN57917442
  • [Publication-type] Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Indicators and Reagents; 9000-29-7 / Guaiac
  •  go-up   go-down


90. Lana E, Brun ME, Rivals I, Selves J, Kirzin S, Lutsyk AP, Gordiyuk VV, Bibeau F, Rynditch A, De Sario A: BAGE Hypomethylation Is an Early Event in Colon Transformation and Is Frequent in Histologically Advanced Adenomas. Cancers (Basel); 2009;1(1):3-11
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] BAGE Hypomethylation Is an Early Event in Colon Transformation and Is Frequent in Histologically Advanced Adenomas.
  • In this study, we show that hypomethylation of BAGE loci was an early event that occurred in 43% of colorectal adenomas.
  • Interestingly, hypomethylation of BAGE loci was frequent (50%) in tubulo-villous and villous adenomas, these adenomas having a high probability of being transformed into colorectal cancers.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 24280968.001).
  • [ISSN] 2072-6694
  • [Journal-full-title] Cancers
  • [ISO-abbreviation] Cancers (Basel)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Other-IDs] NLM/ PMC3757347
  •  go-up   go-down


91. Stein B, Anderson JC, Rajapakse R, Alpern ZA, Messina CR, Walker G: Body mass index as a predictor of colorectal neoplasia in ethnically diverse screening population. Dig Dis Sci; 2010 Oct;55(10):2945-52
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • AIMS: We designed a cross-sectional study to further examine the predictive value of obesity for colorectal adenomas in asymptomatic patients.
  • Patients underwent complete colonoscopy using high-definition colonoscope to detect colorectal adenomas.
  • We defined advanced neoplasia as large (≥ 1 cm) adenoma, villous adenoma, high-grade dysplasia or cancer.
  • Overall, 40 patients (6.7%) had advanced neoplasia and 216 (36.3%) had any adenoma.
  • There were 185 obese patients (30.8%), who had a prevalence of 44.3% for any adenoma and 13.0% for advanced neoplasia.
  • [MeSH-major] Adenoma / ethnology. Body Mass Index. Colorectal Neoplasms / ethnology. Ethnic Groups / statistics & numerical data. Mass Screening / statistics & numerical data

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Dig Dis Sci. 2010 Nov;55(11):3292-3; author reply 3293 [20464494.001]
  • [Cites] J Natl Cancer Inst. 2005 Nov 16;97(22):1679-87 [16288121.001]
  • [Cites] JAMA. 2006 Apr 5;295(13):1549-55 [16595758.001]
  • [Cites] J Gen Intern Med. 2004 Apr;19(4):332-8 [15061742.001]
  • [Cites] J Natl Cancer Inst. 2002 Jul 3;94(13):972-80 [12096082.001]
  • [Cites] Gastrointest Endosc. 1997 Dec;46(6):492-6 [9434214.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2003 May;12(5):412-8 [12750235.001]
  • [Cites] Gastrointest Endosc. 2001 Nov;54(5):662-7 [11677497.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 1996 Dec;5(12):1013-5 [8959325.001]
  • [Cites] JAMA. 2003 Dec 10;290(22):2959-67 [14665657.001]
  • [Cites] Br J Cancer. 2001 Feb 2;84(3):417-22 [11161410.001]
  • [Cites] BMC Gastroenterol. 2006 Jan 13;6:5 [16412216.001]
  • [Cites] Am J Med. 2007 Mar;120(3):257-63 [17349449.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2005 Apr;14(4):850-5 [15824155.001]
  • [Cites] Am J Epidemiol. 1999 Aug 15;150(4):390-8 [10453815.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2007 Mar;16(3):526-31 [17372248.001]
  • [Cites] Am J Gastroenterol. 2003 Dec;98(12):2777-83 [14687832.001]
  • [Cites] J Nutr Biochem. 2006 Mar;17(3):145-56 [16426829.001]
  • [Cites] Cancer Causes Control. 1996 Mar;7(2):253-63 [8740738.001]
  • [Cites] J Natl Cancer Inst. 2004 Apr 7;96(7):546-53 [15069117.001]
  • [Cites] Am J Clin Nutr. 2007 Sep;86(3):556-65 [17823417.001]
  • [Cites] JAMA. 2005 Jan 12;293(2):194-202 [15644546.001]
  • [Cites] Am J Gastroenterol. 2009 Mar;104(3):739-50 [19240699.001]
  • [Cites] Int J Obes Relat Metab Disord. 2004 Apr;28(4):559-67 [14770200.001]
  • [Cites] J Cell Physiol. 2000 Apr;183(1):1-9 [10699960.001]
  • [Cites] Gastrointest Endosc. 2008 Oct;68(4 Suppl):S3-47 [18805238.001]
  • [Cites] N Engl J Med. 2000 Jul 20;343(3):162-8 [10900274.001]
  • [Cites] Ann Intern Med. 1995 Mar 1;122(5):327-34 [7847643.001]
  • [Cites] J Clin Gastroenterol. 2007 Mar;41(3):285-90 [17426468.001]
  • [Cites] Am J Gastroenterol. 2005 Dec;100(12):2756-8 [16393231.001]
  • [Cites] J Gastroenterol Hepatol. 2008 Mar;23 (3):411-7 [17725596.001]
  • [Cites] Endocrinology. 2006 Apr;147(4):1830-7 [16410309.001]
  • [Cites] Int J Cancer. 2006 Feb 1;118(3):728-38 [16094628.001]
  • [Cites] J Clin Oncol. 2009 Feb 10;27(5):686-93 [19114701.001]
  • [Cites] World J Gastroenterol. 2007 Aug 21;13(31):4199-206 [17696248.001]
  • [Cites] Am J Gastroenterol. 2006 Feb;101(2):255-62 [16454827.001]
  • [Cites] Am J Gastroenterol. 2003 Dec;98(12):2648-54 [14687811.001]
  • [Cites] Am J Gastroenterol. 2008 Aug;103(8):2061-7 [18796100.001]
  • [Cites] Arch Intern Med. 2006 Sep 25;166(17):1871-7 [17000944.001]
  • (PMID = 20112063.001).
  • [ISSN] 1573-2568
  • [Journal-full-title] Digestive diseases and sciences
  • [ISO-abbreviation] Dig. Dis. Sci.
  • [Language] eng
  • [Grant] United States / NCRR NIH HHS / RR / MO1RR10710
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  •  go-up   go-down


92. Wang LP, Chen J, Ning HY, Zhang XZ, Cheng J, Li L, Wang B, Dai XJ, Zhu HY, Miao JH, Wang L: [Serrated lesions of colon and their malignant potential]. Zhonghua Bing Li Xue Za Zhi; 2010 Jul;39(7):447-51
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To study the serrated lesions of colon and to compare the malignant potential between traditional serrated adenomas (TSA) and conventional adenomas (CAD).
  • One hundred and eighty-seven cases of CAD (including 160 cases of tubular adenoma and 27 cases of villous adenoma) and 36 cases of invasive adenocarcinoma were randomly selected as the controls.
  • RESULTS: Amongst the 5347 colorectal polyps studied, 258 cases (4.8%) of serrated lesions were found, which included 112 cases (43.4%, 112/258) of hyperplastic polyp, 78 cases (30.2%, 78/258) of TSA and 26 cases (10.1%, 26/258) of sessile serrated adenoma.
  • [MeSH-major] Adenoma / pathology. Cell Transformation, Neoplastic / pathology. Colorectal Neoplasms / pathology. Intestinal Polyps / pathology
  • [MeSH-minor] Adenocarcinoma / metabolism. Adenocarcinoma / pathology. Adenoma, Villous / classification. Adenoma, Villous / metabolism. Adenoma, Villous / pathology. Colonic Polyps / metabolism. Colonic Polyps / pathology. Humans. Ki-67 Antigen / metabolism. Precancerous Conditions / metabolism. Precancerous Conditions / pathology. Rectum / pathology. Retrospective Studies. Tumor Suppressor Protein p53 / metabolism. beta Catenin / metabolism

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21055172.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] Comparative Study; English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Ki-67 Antigen; 0 / Tumor Suppressor Protein p53; 0 / beta Catenin
  •  go-up   go-down


93. Thomas AA, Rackley RR, Lee U, Goldman HB, Vasavada SP, Hansel DE: Urethral diverticula in 90 female patients: a study with emphasis on neoplastic alterations. J Urol; 2008 Dec;180(6):2463-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The most common clinical finding was urinary incontinence (29 of 78 women or 37%).
  • Superficial changes associated with invasive carcinoma included villous adenoma in 1 case, intestinal metaplasia in 2 and high grade dysplasia in 3.
  • Of the 90 patients the remaining 82 demonstrated benign findings, including nephrogenic adenoma in 10 (11%).
  • In 2 patients with invasive adenocarcinoma metastatic disease subsequently developed, of which they died.
  • Due to the risk of malignancy in a subset of patients careful clinical examination and followup are warranted in all patients to exclude neoplastic disease.

  • MedlinePlus Health Information. consumer health - Urethral Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18930487.001).
  • [ISSN] 1527-3792
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


94. Schell AJ, Nickel CJ, Isotalo PA: Complex mucinous cystadenoma of undetermined malignant potential of the urachus. Can Urol Assoc J; 2009 Aug;3(4):E39-E41
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Urachal mucinous neoplasms are rare and include both villous adenomas and invasive adenocarcinomas.
  • Rarely described in the English literature, mucinous cystadenomas of the urachus should be treated similarly to their villous adenoma counterparts: with complete surgical excision to prevent local tumour recurrences.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19672436.001).
  • [ISSN] 1911-6470
  • [Journal-full-title] Canadian Urological Association journal = Journal de l'Association des urologues du Canada
  • [ISO-abbreviation] Can Urol Assoc J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
  •  go-up   go-down


95. Fiducia G, Gandolfo L, Bosco V: [Protruding isolated rectal and anal neoplastic polyps removed by local transanal excision: our experience with 16 cases]. Chir Ital; 2008 Mar-Apr;60(2):227-32
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Local transanal excision as primary treatment of rectal and anal canal adenomas in selected patients is supported by the recent literature.
  • Histologically, 2 were tubular adenomas without atypia (12.5%), 3 were tubulo-villous adenomas with moderate atypia (18.75%), 8 were tubulo-villous adenomas (50%) with severe atypia, 2 were tubulo-villous adenomas with locally invasive foci of adenocarcinoma (12.5%), and 1 case was a pT1 cloacogenic carcinoma (6.25%).

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18689170.001).
  • [ISSN] 0009-4773
  • [Journal-full-title] Chirurgia italiana
  • [ISO-abbreviation] Chir Ital
  • [Language] ita
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


96. Neneman B, Gasiorowska A, Małecka-Panas E: The efficacy and safety of argon plasma coagulation (APC) in the management of polyp remnants in stomach and colon. Adv Med Sci; 2006;51:88-93
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: Pathologic examination revealed 10 hyperplastic polyps and 12 tubular adenomas of the stomach.
  • Among colonic polyps there were: 17 hyperplastic, 26 tubular, 8 tubulo-villous, 4 villous adenomas and 3 inflammatory pseudopolyps.
  • A significant positive correlation between the power output and the size, distal location and villous texture of the polyp has been demonstrated.
  • In the case of colonic polyps the application of higher electric power should be recommended in case of large-sized lesions, located in rectum and of villous texture.
  • [MeSH-minor] Adenoma / pathology. Adenoma / surgery. Adult. Aged. Argon / therapeutic use. Colonoscopy. Endoscopy. Female. Humans. Male. Middle Aged. Prospective Studies. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • Hazardous Substances Data Bank. Argon, Elemental .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17357283.001).
  • [ISSN] 1896-1126
  • [Journal-full-title] Advances in medical sciences
  • [ISO-abbreviation] Adv Med Sci
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 67XQY1V3KH / Argon
  •  go-up   go-down


97. Galamb O, Sipos F, Spisák S, Galamb B, Krenács T, Valcz G, Tulassay Z, Molnár B: Potential biomarkers of colorectal adenoma-dysplasia-carcinoma progression: mRNA expression profiling and in situ protein detection on TMAs reveal 15 sequentially upregulated and 2 downregulated genes. Cell Oncol; 2009;31(1):19-29
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Potential biomarkers of colorectal adenoma-dysplasia-carcinoma progression: mRNA expression profiling and in situ protein detection on TMAs reveal 15 sequentially upregulated and 2 downregulated genes.
  • BACKGROUND: As most colorectal cancers (CRC) develop from villous adenomas, studying alterations in gene expression profiles across the colorectal adenoma-dysplasia-carcinoma sequence may yield potential biomarkers of disease progression.
  • METHODS: Total RNA was extracted, amplified, and biotinylated from colonic biopsies of 15 patients with CRC, 15 with villous adenoma and 8 normal controls.
  • Gene expression profiles were evaluated using HGU133Plus2.0 microarrays and disease progression associated data were validated with RT-PCR.
  • RESULTS: 17 genes were validated to show sequentially altered expression at mRNA level through the normal-adenoma-dysplasia-carcinoma progression.
  • CONCLUSIONS: Downregulated AMN and PTGDR and upregulated osteopontin and osteonectin were found as potential biomarkers of colorectal carcinogenesis and disease progression to be utilized for prospective biopsy screening both at mRNA and protein levels.
  • [MeSH-major] Adenoma / genetics. Biomarkers, Tumor / genetics. Colorectal Neoplasms / genetics. Disease Progression. Gene Expression Profiling. Gene Expression Regulation

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19096147.001).
  • [ISSN] 1875-8606
  • [Journal-full-title] Cellular oncology : the official journal of the International Society for Cellular Oncology
  • [ISO-abbreviation] Cell. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / RNA, Messenger
  • [Other-IDs] NLM/ PMC4618585
  •  go-up   go-down


98. Colvin M, Delis A, Bracamonte E, Villar H, Leon LR Jr: Infiltrating adenocarcinoma arising in a villous adenoma of the anal canal. World J Gastroenterol; 2009 Jul 28;15(28):3560-4
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Infiltrating adenocarcinoma arising in a villous adenoma of the anal canal.
  • In particular, adenomas and adenocarcinomas are distinctly rare entities in this region.
  • We describe an infiltrating, well-differentiated adenocarcinoma arising in a villous adenoma from the distal anal canal, in an otherwise healthy patient at low risk for gastrointestinal malignancy.
  • Microscopic evaluation revealed an infiltrating well-differentiated adenocarcinoma, arising from a villous adenoma.
  • Our report is the first describing the possible malignant degeneration of a villous adenoma in the anal canal.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma, Villous / pathology. Anal Canal / pathology
  • [MeSH-minor] Aged, 80 and over. Cell Transformation, Neoplastic / pathology. Disease Progression. Humans. Male. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Am Surg. 2000 Aug;66(8):789-92 [10966042.001]
  • [Cites] Colorectal Dis. 2008 Jul;10(6):621-3 [17949443.001]
  • [Cites] Histopathology. 2002 Mar;40(3):302-4 [11895502.001]
  • [Cites] Dis Colon Rectum. 2003 Oct;46(10):1320-4 [14530668.001]
  • [Cites] Surg Oncol Clin N Am. 2004 Apr;13(2):249-62 [15137955.001]
  • [Cites] Cancer. 1975 Dec;36(6):2251-70 [1203876.001]
  • [Cites] N Engl J Med. 1988 Sep 1;319(9):525-32 [2841597.001]
  • [Cites] N Engl J Med. 1993 Dec 30;329(27):1977-81 [8247072.001]
  • [Cites] Br J Surg. 1994 Apr;81(4):500-8 [8205420.001]
  • [Cites] Br J Surg. 1995 Dec;82(12):1634 [8548224.001]
  • [Cites] J Clin Pathol. 2005 Feb;58(2):217-9 [15677547.001]
  • [Cites] World J Gastroenterol. 2006 Mar 21;12(11):1780-1 [16586552.001]
  • [Cites] Colorectal Dis. 2006 May;8(4):296-301 [16630233.001]
  • [Cites] Eur J Dermatol. 2006 Sep-Oct;16(5):576-8 [17101482.001]
  • [Cites] World J Gastroenterol. 2006 Dec 7;12(45):7304-8 [17143945.001]
  • [Cites] Gan To Kagaku Ryoho. 2006 Nov;33(12):1977-9 [17212165.001]
  • [Cites] Oncologist. 2007 May;12(5):524-34 [17522240.001]
  • [Cites] Surg Today. 2007;37(7):596-9 [17593481.001]
  • [Cites] Tech Coloproctol. 2007 Dec;11(4):340-2 [18060528.001]
  • [Cites] J Am Osteopath Assoc. 2001 Aug;101(8):450-3 [11526879.001]
  • (PMID = 19630115.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2715986
  •  go-up   go-down


99. Balbinotti RA, Ribeiro U Jr, Sakai P, Safatle-Ribeiro AV, Balbinotti SS, Scapulatempo C, Alves VA, Corbett CE, Carrilho FJ: hMLH1, hMSH2 and cyclooxygenase-2 (cox-2) in sporadic colorectal polyps. Anticancer Res; 2007 Nov-Dec;27(6C):4465-71
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: Tubular adenomas were present in 81.4%, tubulous-villous in 15.9%, serrated in 1.8%, and villous in 0.9%.
  • The majority of the adenomas were located in the rectosigmoid region (63.5%), followed by ascendant in 14.2%, cecum in 7.5%, descendent in 8.2% and transverse in 6.7%.
  • Low-grade dysplasia was detected in 59.6% of the adenomas.
  • Loss of hMLH1 and hMLH2 immunoexpression was observed in 20% and 15.5% of the adenomas, respectively.
  • Cox-2 expression was found in 9% of the adenomas, and in 40% of the adenocarcinomas.
  • Moreover, Cox-2 immunoexpression was associated with the multiplicity of adenomas in the same patient (p=0.001).
  • CONCLUSION: Loss of hMLH1 and hMLH2 immunoexpression in adenomas is relatively frequent in patients without colorectal cancer family history.
  • Cox-2 is overexpressed in colorectal adenomatous polyps and adenocarcinomas, and its positivity in adenomas may indicate a higher risk for multiple lesions.

  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18214062.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Adaptor Proteins, Signal Transducing; 0 / MLH1 protein, human; 0 / Nuclear Proteins; EC 1.14.99.1 / Cyclooxygenase 2; EC 3.6.1.3 / MSH2 protein, human; EC 3.6.1.3 / MutS Homolog 2 Protein
  •  go-up   go-down


100. Ciatto S, Martinelli F, Castiglione G, Mantellini P, Rubeca T, Grazzini G, Bonanomi AG, Confortini M, Zappa M: Association of FOBT-assessed faecal Hb content with colonic lesions detected in the Florence screening programme. Br J Cancer; 2007 Jan 29;96(2):218-21
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We assessed the correlation between quantitative results of immunological faecal occult blood testing (I-FOBT) and colonic lesions (191 colorectal cancers, 890 adenomas) detected at colonoscopy in 2597 FOBT+ (cutoff 100 ng ml(-1) Hb) subjects.
  • Among adenomas, higher faecal Hb content was significantly associated with size (P=0.0000), presence of severe dysplasia (P=0.0001), presence of villous component (P=0.0002), and location in the left colon (P=0.003).
  • Immunological FOBT is confirmed to be a specific screening test to detect cancer and adenoma, with a low positivity rate (3.7%) and a high positive predictive value (41.5%).
  • Faecal Hb content is significantly higher for those lesions (cancer and high-risk adenomas) screening is aimed at detecting.

  • MedlinePlus Health Information. consumer health - Bowel Movement.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Eur J Cancer. 1999 Jun;35(6):973-7 [10533481.001]
  • [Cites] Epidemiol Prev. 2006 Jan-Feb;30(1 Suppl 3):41-50 [16937845.001]
  • [Cites] Eur J Cancer. 2000 Aug;36(12):1473-8 [10930794.001]
  • [Cites] N Engl J Med. 2000 Nov 30;343(22):1603-7 [11096167.001]
  • [Cites] J Med Screen. 2002;9(3):99-103 [12370319.001]
  • [Cites] Ann Intern Med. 1993 Jan 1;118(1):1-6 [8416152.001]
  • [Cites] N Engl J Med. 1993 May 13;328(19):1365-71 [8474513.001]
  • [Cites] JAMA. 1994 Apr 6;271(13):1011-3 [8139058.001]
  • [Cites] Int J Cancer. 1995 May 16;61(4):465-9 [7759151.001]
  • [Cites] Br J Cancer. 1996 Jul;74(1):141-4 [8679448.001]
  • [Cites] Lancet. 1996 Nov 30;348(9040):1467-71 [8942774.001]
  • [Cites] Lancet. 1996 Nov 30;348(9040):1472-7 [8942775.001]
  • [Cites] J Natl Cancer Inst. 1997 Oct 1;89(19):1423-8 [9326911.001]
  • [Cites] Int J Cancer. 1997 Oct 9;73(2):208-10 [9335444.001]
  • [Cites] J Med Screen. 1997;4(3):142-6 [9368871.001]
  • [Cites] Am J Gastroenterol. 2005 Nov;100(11):2519-25 [16279909.001]
  • [Cites] Pathology. 2005 Dec;37(6):565-8 [16373240.001]
  • [Cites] J Med Screen. 2000;7(1):35-7 [10807145.001]
  • (PMID = 17211476.001).
  • [ISSN] 0007-0920
  • [Journal-full-title] British journal of cancer
  • [ISO-abbreviation] Br. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Hemoglobins
  • [Other-IDs] NLM/ PMC2359986
  •  go-up   go-down






Advertisement