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1. Singh S, Shivamurthy DM, Agarwal R: Pleomorphic adenoma of the soft palate. J Maxillofac Oral Surg; 2010 Mar;9(1):76-7
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  • [Title] Pleomorphic adenoma of the soft palate.
  • Pleomorphic adenoma is the commonest benign salivary gland tumour, accounting for almost three fourths of all such tumours.
  • Pleomorphic adenoma most commonly occurs in the parotid gland; however it is also encountered in the submandibular, sublingual and minor salivary glands.Almost half of all salivary gland tumours are malignant, pleomorphic adenoma is the commonest benign lesion.A case of pleomorphic adenoma arising denovo in the minor salivary glands is discussed.

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  • [Cites] Oral Surg Oral Med Oral Pathol. 1988 Sep;66(3):323-33 [2845326.001]
  • [Cites] Int J Oral Maxillofac Surg. 1986 Dec;15(6):777-9 [3027209.001]
  • [Cites] Head Neck Surg. 1986 Jan-Feb;8(3):177-84 [3744850.001]
  • (PMID = 23139574.001).
  • [ISSN] 0972-8279
  • [Journal-full-title] Journal of maxillofacial and oral surgery
  • [ISO-abbreviation] J Maxillofac Oral Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3453680
  • [Keywords] NOTNLM ; Minor salivary gland tumours / Pleomorphic adenoma
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2. Hervieu V, Scoazec JY: [Mixed endocrine tumors]. Ann Pathol; 2005 Dec;25(6):511-28
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  • [Title] [Mixed endocrine tumors].
  • Mixed endocrine tumors are tumors composed of at least two distinct tumor populations, one of which is endocrine.
  • Because of their rarity and unusual presentation, endocrine mixed tumors raise many problems of diagnosis, management and therapy.
  • Three main types of endocrine mixed tumors are recognized: The existence of these various types has been confirmed by recent molecular studies, even if the same studies have also shown that the histogenesis of a mixed endocrine tumor cannot be predicted from its histological features.
  • Composite tumors are the less rare mixed tumors.
  • The recent WHO classification recommends to restrict the term of composite endocrine tumor to the epithelial tumors containing at least 30% of obviously tumoral endocrine cells; some authors recommend to use higher thresholds, of at least 50%, in order to avoid overdiagnosis.
  • The endocrine component is usually well differentiated, easily identified by its suggestive histological features; the endocrine nature of tumor cells is confirmed by the immunodetection of specific endocrine and neuro-endocrine markers (such as chromogranin A and synaptophysin).
  • Mixed tumors can occur in every anatomical site; they are more frequent in organs containing endocrine cells in the normal state (especially the digestive tract and the pancreas), but they can also be observed in organs devoid of endocrine cells (such as the mammary gland).
  • The management of mixed endocrine tumors must take into account the more aggressive component.
  • Mixed tumors containing a well differentiated endocrine component and an adenocarcinomatous component are to be treated like adenocarcinomas.
  • Mixed tumors containing a poorly differentiated endocrine component must be considered as poorly differentiated endocrine carcinomas.
  • [MeSH-major] Digestive System Neoplasms / pathology. Endocrine Gland Neoplasms / pathology

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  • (PMID = 16735976.001).
  • [ISSN] 0242-6498
  • [Journal-full-title] Annales de pathologie
  • [ISO-abbreviation] Ann Pathol
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 128
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3. Driemel O, Kraft K, Hemmer J: Flow cytometric S-phase fraction contributes to diagnosis of diploid malignant salivary gland tumours. Int J Oral Maxillofac Surg; 2006 Oct;35(10):947-50
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  • [Title] Flow cytometric S-phase fraction contributes to diagnosis of diploid malignant salivary gland tumours.
  • DNA ploidy studies on salivary gland tumours have shown that the proportion of aneuploid cases, although confined to the malignant entities, is considerably lower than for other solid malignancies.
  • To analyse whether the S-phase fraction (SPF) may contribute to discrimination of diploid malignant from benign tumours, DNA flow cytometric data from 45 different malignant salivary gland tumours was compared with that of 121 pleomorphic adenomas.
  • All benign tumours were diploid.
  • The SPF values for diploid malignancies ranged between 0.9% and 11.0% (mean 3.9%), and between 0.5% and 7.9% (mean 2.7%) for pleomorphic adenomas.
  • A 4% cut-off value gained statistical significance for discriminating diploid malignant tumours from pleomorphic adenomas (P<0.01).
  • These results show that DNA flow cytometry may contribute to diagnostic assessment in salivary gland tumours.
  • [MeSH-major] DNA, Neoplasm / analysis. Diploidy. Flow Cytometry / methods. S Phase. Salivary Gland Neoplasms / diagnosis
  • [MeSH-minor] Adenoma, Pleomorphic / diagnosis. Adenoma, Pleomorphic / genetics. Adenoma, Pleomorphic / pathology. Adult. Aged. Aged, 80 and over. Aneuploidy. Diagnosis, Differential. Epidemiologic Methods. Female. Humans. Male. Middle Aged. Salivary Glands / pathology

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  • (PMID = 16829041.001).
  • [ISSN] 0901-5027
  • [Journal-full-title] International journal of oral and maxillofacial surgery
  • [ISO-abbreviation] Int J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / DNA, Neoplasm
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4. Benoit MM, Handzel O, McKenna MJ, Deschler DG: A 42-year-old man with facial nerve weakness and multiple recurrent pleomorphic adenoma. Otol Neurotol; 2010 Sep;31(7):1157-9
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  • [Title] A 42-year-old man with facial nerve weakness and multiple recurrent pleomorphic adenoma.
  • OBJECTIVE: To describe a case and discuss the differential diagnosis of facial nerve paresis presenting years after resection of multiple recurrent parotid pleomorphic adenoma.
  • PATIENTS: Case report of a patient on immunosuppressive therapy with facial nerve weakness 3 years after last resection for multiple recurrent pleomorphic adenoma.
  • RESULTS: Final diagnosis of recurrent pleomorphic adenoma causing compression of the facial nerve at the stylomastoid foramen.
  • CONCLUSION: Facial nerve weakness caused by a benign salivary gland tumor is rare.
  • Although alternate diagnoses must be considered, recurrent pleomorphic adenoma alone may impair facial function by impinging on the nerve in the stylomastoid foramen.
  • [MeSH-major] Adenoma, Pleomorphic / complications. Facial Paralysis / etiology. Parotid Neoplasms / complications

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  • (PMID = 20657328.001).
  • [ISSN] 1537-4505
  • [Journal-full-title] Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • [ISO-abbreviation] Otol. Neurotol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Immunosuppressive Agents
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5. Poetsch M, Zimmermann A, Wolf E, Kleist B: Loss of heterozygosity occurs predominantly, but not exclusively, in the epithelial compartment of pleomorphic adenoma. Neoplasia; 2005 Jul;7(7):688-95
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  • [Title] Loss of heterozygosity occurs predominantly, but not exclusively, in the epithelial compartment of pleomorphic adenoma.
  • Pleomorphic adenoma (PA), being the most common benign tumor of the salivary glands, is composed of epithelial and mesenchymal compartments.
  • In this study, we analyzed 19 microsatellite markers from chromosomal arms 6q, 8q, 9p, 12q, and 17p in 31 PAs and 3 carcinoma ex pleomorphic adenomas (CXPAs) as well as 11 other non-PA-related carcinomas of the salivary gland for comparison.
  • LOH could not only be detected in the epithelial, but also in the mesenchymal, compartments of a subset of PAs, especially at chromosomal arm 8q.
  • Concerning the CXPAs, we were able to demonstrate allelic losses not only in the malignant epithelial compartment, but also in the residual adenoma parts.
  • [MeSH-major] Adenoma, Pleomorphic / genetics. Adenoma, Pleomorphic / pathology. Loss of Heterozygosity. Microsatellite Repeats. Salivary Gland Neoplasms / genetics
  • [MeSH-minor] Adolescent. Adult. Aged. Alleles. Chromosomes, Human, Pair 12. Chromosomes, Human, Pair 8. DNA / metabolism. Epithelium / pathology. Female. Humans. Male. Mesoderm / pathology. Middle Aged. Salivary Glands / pathology

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  • [Cites] Genes Chromosomes Cancer. 2000 Feb;27(2):162-8 [10612804.001]
  • [Cites] Int J Oral Maxillofac Surg. 2001 Dec;30(6):538-44 [11829237.001]
  • [Cites] Cancer Genet Cytogenet. 2001 Feb;125(1):21-6 [11297763.001]
  • [Cites] Virchows Arch. 2002 Jan;440(1):77-84 [11942580.001]
  • [Cites] J Pathol. 2002 Nov;198(3):326-34 [12375265.001]
  • [Cites] Virchows Arch. 2002 Nov;441(5):428-36 [12447671.001]
  • [Cites] Mol Pathol. 2003 Jun;56(3):141-9 [12782760.001]
  • [Cites] Cancer Sci. 2003 Jun;94(6):530-5 [12824879.001]
  • [Cites] Genes Chromosomes Cancer. 2004 Jan;39(1):93-8 [14603447.001]
  • [Cites] J Oral Pathol Med. 2004 Feb;33(2):96-101 [14720195.001]
  • [Cites] J Oral Pathol Med. 2004 Aug;33(7):435-40 [15250837.001]
  • [Cites] Histopathology. 2004 Aug;45(2):187-92 [15279638.001]
  • [Cites] Cancer. 1978 Nov;42(5):2407-11 [719617.001]
  • [Cites] Hum Pathol. 1983 Sep;14(9):780-97 [6309645.001]
  • [Cites] Am J Surg Pathol. 1984 Nov;8(11):803-20 [6209992.001]
  • [Cites] Anticancer Res. 1986 Mar-Apr;6(2):299-308 [3707067.001]
  • [Cites] Cytogenet Cell Genet. 1987;45(3-4):187-90 [3691185.001]
  • [Cites] Genetica. 1987 Jun 15;72(2):85-92 [3505884.001]
  • [Cites] Virchows Arch A Pathol Anat Histopathol. 1992;421(2):95-104 [1325089.001]
  • [Cites] Genes Chromosomes Cancer. 1992 Jul;5(1):35-9 [1384660.001]
  • [Cites] Pathol Annu. 1993;28 Pt 1:279-328 [8380049.001]
  • [Cites] Cancer Genet Cytogenet. 1993 Jan;65(1):27-31 [8381711.001]
  • [Cites] J Pathol. 1993 Nov;171(3):173-81 [7506306.001]
  • [Cites] Cancer Res. 1996 Mar 1;56(5):1151-4 [8640776.001]
  • [Cites] Hum Pathol. 1996 Aug;27(8):782-6 [8760010.001]
  • [Cites] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1996 Aug;82(2):187-92 [8863309.001]
  • [Cites] Am J Surg Pathol. 1997 Jun;21(6):691-7 [9199647.001]
  • [Cites] Cancer Res. 1997 Jul 15;57(14):3010-5 [9230216.001]
  • [Cites] Otolaryngol Head Neck Surg. 1997 Nov;117(5):448-52 [9374165.001]
  • [Cites] Oncogene. 1998 Jan 8;16(1):83-8 [9467946.001]
  • [Cites] Cancer Genet Cytogenet. 1998 Apr 1;102(1):19-24 [9530335.001]
  • [Cites] Diagn Mol Pathol. 1998 Aug;7(4):224-31 [9917133.001]
  • [Cites] Int J Pancreatol. 1999 Apr;25(2):97-102 [10360221.001]
  • [Cites] Oncol Rep. 2004 Dec;12(6):1263-8 [15547748.001]
  • [Cites] Oral Oncol. 2005 Feb;41(2):161-9 [15695118.001]
  • [Cites] Int J Oncol. 2001 Aug;19(2):401-5 [11445859.001]
  • [Cites] Neoplasia. 2001 May-Jun;3(3):173-8 [11494110.001]
  • [Cites] Head Neck. 2001 Dec;23(12):1037-42 [11774388.001]
  • [Cites] Laryngoscope. 2001 Dec;111(12):2195-200 [11802025.001]
  • [Cites] Oral Oncol. 2000 Jul;36(4):360-4 [10899675.001]
  • (PMID = 16026648.001).
  • [ISSN] 1522-8002
  • [Journal-full-title] Neoplasia (New York, N.Y.)
  • [ISO-abbreviation] Neoplasia
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 9007-49-2 / DNA
  • [Other-IDs] NLM/ PMC1501429
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6. Hara H, Oyama T, Saku T: Fine needle aspiration cytology of basal cell adenoma of the salivary gland. Acta Cytol; 2007 Sep-Oct;51(5):685-91
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  • [Title] Fine needle aspiration cytology of basal cell adenoma of the salivary gland.
  • OBJECTIVE: To formulate cytologic features for differential diagnosis of basal cell adenoma (BCA).
  • The 5 items in 8 BCA and 22 non-BCA cases (adenoid cystic carcinoma [ADCC], basal cell adenocarcinoma, myoepithelioma, pleomorphic adenoma and polymorphous low-grade adenocarcinoma) that displayed mimicking cytology were examined cytologically.
  • [MeSH-major] Adenoma / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands / pathology

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  • (PMID = 17910337.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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7. Shelekhova KV, Kazakov DV, Hes O, Treska V, Michal M: Phosphaturic mesenchymal tumor (mixed connective tissue variant): a case report with spectral analysis. Virchows Arch; 2006 Feb;448(2):232-5
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  • [Title] Phosphaturic mesenchymal tumor (mixed connective tissue variant): a case report with spectral analysis.
  • We present a further case of a rare mesenchymal neoplasm termed phosphaturic mesenchymal tumor (mixed connective tissue variant).
  • The patient was a 42-year-old man with a long history of osteomalacia of unknown etiology with pathological bone fracture, abnormality of parathyroid glands, kyphosis, scoliosis, and spondylosis.
  • The tumor was surgically removed.
  • Grossly, the tumor was well circumscribed, unencapsulated, and had soft to dense consistency.
  • Histologically, the tumor was composed of primitive mesenchymal cells, osteoclast-like cells, and cells showing myofibroblastic features without cytologic atypia.
  • Unusual and hitherto unpublished prominent features were flower-like, slate-gray crystals, widespread hemosiderin deposits and large areas of hemorrhages, with the latter comprising approximately 60% of the tumor.

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  • [Cites] Cancer. 1987 Apr 15;59(8):1442-54 [3545439.001]
  • [Cites] Tumori. 1988 Oct 31;74(5):599-607 [3217995.001]
  • [Cites] Am J Med. 1987 Aug;83(2):350-4 [3303928.001]
  • [Cites] Am J Med. 1985 Apr;78(4):669-73 [2984933.001]
  • [Cites] Am J Surg Pathol. 2004 Jan;28(1):1-30 [14707860.001]
  • [Cites] Acta Oncol. 1994;33(8):975-6 [7818934.001]
  • [Cites] Ultrastruct Pathol. 1991 Jul-Oct;15(4-5):317-33 [1755097.001]
  • [Cites] Korean J Intern Med. 1997 Jan;12 (1):89-95 [9159046.001]
  • [Cites] J Clin Pathol. 1987 Apr;40(4):446-53 [3584490.001]
  • (PMID = 16447065.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Calcium Phosphates; 0 / Nitrates; 8M4L3H2ZVZ / sodium nitrate; EC 3.1.3.1 / Alkaline Phosphatase; SY7Q814VUP / Calcium
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8. Ogawa R, Mitsuhashi K, Oki K, Hyakusoku H: A rare case of chondroid syringoma arising from the lower eyelid with ectropion. Plast Reconstr Surg; 2006 Nov;118(6):137e-140e
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  • [Title] A rare case of chondroid syringoma arising from the lower eyelid with ectropion.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Eyelids. Sweat Gland Neoplasms / diagnosis

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  • (PMID = 17051093.001).
  • [ISSN] 1529-4242
  • [Journal-full-title] Plastic and reconstructive surgery
  • [ISO-abbreviation] Plast. Reconstr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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9. Uğuz MZ, Onal HK, Eroğlu OO, Etit D: [Sensitivity and specificity of fine needle aspiration biopsy in parotid masses]. Kulak Burun Bogaz Ihtis Derg; 2007;17(2):96-9
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  • RESULTS: The results of FNAB were reported as benign in 21 patients (72.4%), malignant in six patients (20.7%), and suspicious in two patients (6.9%).
  • Postoperative histopathologic diagnoses were reported as benign in 17 patients (58.6%) and malignant in 12 patients (41.4%).
  • The most common histopathological diagnosis was pleomorphic adenoma (n=7, 24.1%), followed by mucoepidermoid carcinoma (n=4, 13.8%), and Warthin's tumor (n=3, 10.3%).
  • [MeSH-minor] Adenolymphoma / diagnosis. Adenolymphoma / pathology. Adenoma, Pleomorphic / diagnosis. Adenoma, Pleomorphic / pathology. Adult. Aged. Aged, 80 and over. Carcinoma, Mucoepidermoid / diagnosis. Carcinoma, Mucoepidermoid / pathology. Female. Humans. Male. Middle Aged. Predictive Value of Tests. Sensitivity and Specificity

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  • (PMID = 17527061.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] tur
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] Turkey
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10. Pagni F, Fuertes Zàrate A, Ren S: Neural invasion in pleomorphic adenoma of the salivary gland. Int J Surg Pathol; 2010 Apr;18(2):151-2
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  • [Title] Neural invasion in pleomorphic adenoma of the salivary gland.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Neoplasms, Second Primary / pathology. Peripheral Nerves / pathology. Submandibular Gland Neoplasms / pathology

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  • (PMID = 19948638.001).
  • [ISSN] 1940-2465
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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11. Furuse C, Miguita L, Rosa AC, Soares AB, Martinez EF, Altemani A, de Araújo VC: Study of growth factors and receptors in carcinoma ex pleomorphic adenoma. J Oral Pathol Med; 2010 Aug 1;39(7):540-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Study of growth factors and receptors in carcinoma ex pleomorphic adenoma.
  • Carcinoma ex pleomorphic adenoma (CXPA) is a rare malignant salivary gland tumor derived from a pre-existing pleomorphic adenoma.
  • Slides were qualitatively and semi-quantitatively evaluated according to the percentage of stained tumor cells from 0 to 3 (0 = less than 10%; 1 = 10-25%; 2 = 25-50%; 3 = more than 50% of cells).
  • Malignant epithelial cells starting with in situ areas showed stronger expression than luminal cells of pleomorphic adenoma for all antibodies.
  • Altogether this data infers that these factors may contribute to cell proliferation during initial phases of the tumor.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma, Pleomorphic / pathology. Intercellular Signaling Peptides and Proteins / analysis. Parotid Neoplasms / pathology. Receptors, Growth Factor / analysis
  • [MeSH-minor] Adult. Aged. Carcinoma in Situ / pathology. Cell Proliferation. Coloring Agents. Disease Progression. Epithelial Cells / pathology. Female. Fibroblast Growth Factors / analysis. Hepatocyte Growth Factor / analysis. Humans. Male. Middle Aged. Neoplasm Invasiveness. Protein-Serine-Threonine Kinases / analysis. Proto-Oncogene Proteins c-met / analysis. Receptor, Epidermal Growth Factor / analysis. Receptor, Fibroblast Growth Factor, Type 1 / analysis. Receptor, Fibroblast Growth Factor, Type 2 / analysis. Receptor, IGF Type 1 / analysis. Receptors, Transforming Growth Factor beta / analysis. Submandibular Gland Neoplasms / pathology. Transforming Growth Factor beta1 / analysis

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  • (PMID = 20149060.001).
  • [ISSN] 1600-0714
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Coloring Agents; 0 / Intercellular Signaling Peptides and Proteins; 0 / Receptors, Growth Factor; 0 / Receptors, Transforming Growth Factor beta; 0 / Transforming Growth Factor beta1; 62031-54-3 / Fibroblast Growth Factors; 67256-21-7 / Hepatocyte Growth Factor; EC 2.7.10.1 / FGFR1 protein, human; EC 2.7.10.1 / FGFR2 protein, human; EC 2.7.10.1 / Proto-Oncogene Proteins c-met; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; EC 2.7.10.1 / Receptor, Fibroblast Growth Factor, Type 1; EC 2.7.10.1 / Receptor, Fibroblast Growth Factor, Type 2; EC 2.7.10.1 / Receptor, IGF Type 1; EC 2.7.11.1 / Protein-Serine-Threonine Kinases; EC 2.7.11.30 / transforming growth factor-beta type II receptor
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12. Oda E, Nakamura Y, Yamamoto M, Kojiro M: Immunohistochemical distribution of tubulin beta II in human normal and neoplastic tissues. Kurume Med J; 2005;52(4):117-25
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  • In neoplastic tissues, tubulin beta II immunoreactivity was detected in various nervous system neoplasms and other neoplasms such as pancreatic solid cystic carcinoma, pleomorphic adenoma, Warthin's tumor, nephroblastoma, basal cell carcinoma and malignant mesothelioma.
  • We conclude that our monoclonal antibody, KNY379, may be useful as a marker of nervous system neoplasm, pancreatic solid cystic carcinoma, pleomorphic adenoma, Warthin's tumor, nephroblastoma, basal cell carcinoma and malignant mesothelioma.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / analysis. Blotting, Western. Child, Preschool. Humans. Immunohistochemistry. Infant. Mesothelioma / chemistry. Middle Aged. Protein Isoforms

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  • (PMID = 16639982.001).
  • [ISSN] 0023-5679
  • [Journal-full-title] The Kurume medical journal
  • [ISO-abbreviation] Kurume Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Protein Isoforms; 0 / Tubulin
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13. Gamboa-Dominguez A, Dominguez-Fonseca C, Chavarri-Guerra Y, Vargas R, Reyes-Gutierrez E, Green D, Quintanilla-Martinez L, Luber B, Busch R, Becker KF, Becker I, Höfler H, Fend F: E-cadherin expression in sporadic gastric cancer from Mexico: exon 8 and 9 deletions are infrequent events associated with poor survival. Hum Pathol; 2005 Jan;36(1):29-35
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  • Aberrant expression and mutation of E-cadherin is frequent in gastric carcinoma (GC) especially of the diffuse type.
  • One hundred seventy-seven gastrectomies from Mexican mestizo patients with intestinal (53), mixed (55), or diffuse (69) GC were included.
  • Immunohistochemistry against wild-type E-cadherin (clone 36) and against 2 mutation-specific antibodies (MSA) recognizing mutant CDH1 lacking exon-8 (del 8) or exon-9 (del 9) were performed.
  • Staining was correlated with histotype, tumor node metastasis stage, and follow-up.
  • Abnormal or absent E-cadherin expression (clone 36) was identified in 84% GC, predominantly in diffuse or mixed tumors (P = 0.004) in advanced stages (P = 0.003).
  • No survival differences at 1 and 2 years were observed among patients showing normal, abnormal, or absent wild type E-cadherin expression.
  • In 140 patients, dead from the disease or alive with the disease, the survival at 1 and 2 years was 37% versus 17% and 14% versus 0 for patients without and with del 8/9 positivity, respectively (log rank P = 0.01).
  • However, exon 8 or 9 deletions were observed in only 5.3% tumors in this series from Mexico, at a lower rate than previously published, but associated with a worse prognosis.

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  • (PMID = 15712179.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cadherins; EC 1.1.- / Carbohydrate Dehydrogenases; EC 1.1.99.18 / cellobiose-quinone oxidoreductase
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14. Trepp R, Padberg BC, Varga Z, Cathomas R, Inauen R, Reinhart WH: Extensive extranodal metastases of basal-like breast cancer with predominant myoepithelial spindle cell differentiation. Pathol Res Pract; 2010 May 15;206(5):334-7
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  • These include multifocal myoepitheliomatosis, the rare mixed tumor or pleomorphic adenoma, adenoid cystic carcinoma, adenomyoepithelioma and myoepithelial carcinoma (malignant myoepithelioma).
  • All these tumors are benign and/or of low-grade malignancy, with the exception of malignant myoepithelioma.
  • The presented case of a breast carcinoma with dominant myoepithelial/spindle cell differentiation in a 58-year-old woman is an excellent example to document the highly aggressive biological behavior of this tumor phenotype.
  • Despite an extensive chemotherapy and radiotherapy, the tumor was rapidly progressive, forming a finally exulcerating local tumor relapse and widespread metastases to the myocardium, lungs, liver, kidneys and skin.
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Cell Transformation, Neoplastic / pathology. Fatal Outcome. Female. Humans. Middle Aged


15. Teymoortash A, Schrader C, Shimoda H, Kato S, Werner JA: Evidence of lymphangiogenesis in Warthin's tumor of the parotid gland. Oral Oncol; 2007 Jul;43(6):614-8
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  • [Title] Evidence of lymphangiogenesis in Warthin's tumor of the parotid gland.
  • The details of the pathogenesis of cystadenolymphoma (Warthin's tumor) of the parotid gland are still unclear.
  • Neovascularization is considered to be a pivotal factor for solid tumor progression and biological behavior of the tumor.
  • Using double-labeling immunohistochemistry for LYVE-1 and CD34 (specific markers for lymphatic and vascular endothelial cells, respectively) this study analyzes lymphatic vessel density (LVD) and blood vessel density (BVD) in 10 Warthin's tumors and 10 pleomorphic adenomas of the parotid gland as well as in 5 normal parotid glands and 5 normal parotid lymph nodes.
  • There was no significant difference in the intratumoral LVD and BVD among pleomorphic adenoma and normal parotid gland tissue.
  • In contrast, the intratumoral LVD and BVD were significantly higher in Warthin's tumor than pleomorphic adenoma, normal parotid gland and parotid lymph node (P<0.0001 versus P<0.004).
  • The increase in lymphatic vessels in Warthin's tumor suggests that epithelial tumor cells might promote lymphangiogenesis in this kind of lesions.
  • [MeSH-minor] Adenoma, Pleomorphic / blood supply. Adenoma, Pleomorphic / pathology. Antigens, CD34 / metabolism. Endothelial Cells / metabolism. Female. Humans. Immunohistochemistry. Lymph Nodes / blood supply. Male. Middle Aged. Neovascularization, Pathologic / metabolism. Neovascularization, Pathologic / pathology. Vesicular Transport Proteins / metabolism

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  • (PMID = 16996778.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / LYVE1 protein, human; 0 / Vesicular Transport Proteins
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16. Katayam N, Tokuda A, Nakatsumi Y, Oribe Y, Fujimura M: [A case of malignant mesothelioma presenting with recurrent pneumothorax]. Nihon Kokyuki Gakkai Zasshi; 2006 Nov;44(11):807-11
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  • Although pneumothorax was treated successfully, increased pleural effusion, pleural thickening and subcutaneal tumor at the thoracic drainage suture site developed.
  • The histological examination of the biopsied subcutaneous tumor showed mixed type malignant pleural mesothelioma.
  • [MeSH-minor] Aged. Antineoplastic Agents / therapeutic use. Disease Progression. Fatal Outcome. Humans. Male. Picibanil / therapeutic use. Recurrence

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  • (PMID = 17144577.001).
  • [ISSN] 1343-3490
  • [Journal-full-title] Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
  • [ISO-abbreviation] Nihon Kokyuki Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 39325-01-4 / Picibanil
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17. Ethunandan M, Davies B, Pratt CA, Puxeddu R, Brennan PA: Primary epithelial submandibular salivary gland tumours--review of management in a district general hospital setting. Oral Oncol; 2009 Feb;45(2):173-6
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  • [Title] Primary epithelial submandibular salivary gland tumours--review of management in a district general hospital setting.
  • Primary epithelial submandibular gland (SMG) tumours are uncommon, accounting for 8-12% of all salivary gland neoplasms, and most studies come from large specialised centres.
  • Seventeen benign (68%) and eight malignant (32%) tumours were included.
  • Pleomorphic adenoma accounted for all 17 benign tumours and adenoid cystic carcinoma was the commonest malignant tumour.
  • Fine needle aspiration cytology (FNAC) accurately identified 78% of the benign tumours but none of the malignant tumours.
  • Pre-operative imaging was also unable to distinguish malignant from benign tumours.
  • It may be difficult to distinguish benign from malignant SMG tumours on clinical examination and pre-operative investigations.
  • Any suspected submandibular tumour should be considered for early treatment even when FNAC is suggestive of a benign tumour.
  • [MeSH-major] Neoplasms, Glandular and Epithelial / diagnosis. Submandibular Gland Neoplasms / diagnosis

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  • (PMID = 18676173.001).
  • [ISSN] 1879-0593
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] England
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18. Kunimura T: Noninvasive carcinoma ex pleomorphic adenoma of the parotid gland. Otolaryngol Head Neck Surg; 2007 Oct;137(4):687-8
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  • [Title] Noninvasive carcinoma ex pleomorphic adenoma of the parotid gland.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma, Pleomorphic / pathology. Neoplasms, Multiple Primary / pathology. Parotid Neoplasms / pathology

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  • (PMID = 17903596.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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19. Ansari MH: Salivary gland tumors in an Iranian population: a retrospective study of 130 cases. J Oral Maxillofac Surg; 2007 Nov;65(11):2187-94
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  • [Title] Salivary gland tumors in an Iranian population: a retrospective study of 130 cases.
  • PURPOSE: Tumors of the salivary glands are uncommon, comprising 3% to 10% of head and neck neoplasia.
  • PATIENTS AND METHODS: The medical records and case notes of all patients with histologically confirmed salivary gland tumors were reviewed retrospectively from February 1984 to March 2003.
  • This review found 89 patients with benign tumors and 41 patients with malignant tumors.
  • The collection of data included gender, age, location, and histopathology of the tumor.
  • Patients with benign and malignant tumors presented with a mean age of 41.3 and 47 years, respectively.
  • The frequency of benign tumors was 68.4% (n = 89) and 31.6% for malignant tumors (n = 41).
  • Tumors were localized in the parotid gland (63%; n = 82), the submandibular gland (23%; n = 30), and in the minor salivary glands (14%; n = 18).
  • The most common benign tumor was pleomorphic adenoma (65.4%; n = 85).
  • Among malignant tumors, mucoepidermoid carcinoma was the most frequent (11.5%; n = 15), followed by adenocarcinoma (10%; n = 13).
  • Greater than 63% of malignant tumors were treated surgically, and the remaining with combined therapy.
  • Seven patients died over the follow-up period (6 with persistent disease), 5 were lost to follow-up, and 23 remained cancer-free.
  • CONCLUSION: Between benign and malignant salivary gland tumors, frequency of pleomorphic adenoma and mucoepidermoid carcinoma was in keeping with studies reported previously.
  • In other salivary gland tumors, however, diversity was obvious and showed significant difference, requiring further studies.
  • [MeSH-major] Salivary Gland Neoplasms / epidemiology
  • [MeSH-minor] Adenocarcinoma / epidemiology. Adenoma, Pleomorphic / epidemiology. Adolescent. Adult. Aged. Carcinoma, Mucoepidermoid / epidemiology. Disease-Free Survival. Female. Follow-Up Studies. Humans. Iran / epidemiology. Male. Middle Aged. Neoadjuvant Therapy. Parotid Neoplasms / epidemiology. Retrospective Studies. Salivary Glands, Minor / pathology. Submandibular Gland Neoplasms / epidemiology. Survival Rate

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  • (PMID = 17954313.001).
  • [ISSN] 0278-2391
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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20. Olajide TG, Alabi BS, Badmos BK, Bello OT: Pleomorphic adenoma of the lateral nasal wall--a case report. Niger Postgrad Med J; 2009 Sep;16(3):227-9
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  • [Title] Pleomorphic adenoma of the lateral nasal wall--a case report.
  • AIM/BACKGROUND: We report a rare case of pleomorphic adenoma arising from the lateral nasal wall.
  • The microscopic finding showed a lobular duct-like structure within a loose chondromyxoid stroma, which are histological characteristics of pleomorphic adenoma.
  • CONCLUSIONS: Her post-operative clinic visits were uneventful, and she is currently disease-free; nine months after surgery.
  • The diagnosis, clinical behaviour and treatment of pleomorphic adenoma of the lateral nasal wall are discussed from a review of the literature.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Nasal Cavity / radiography. Nose Neoplasms / pathology

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  • (PMID = 19767912.001).
  • [ISSN] 1117-1936
  • [Journal-full-title] The Nigerian postgraduate medical journal
  • [ISO-abbreviation] Niger Postgrad Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Nigeria
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21. Kurokawa H, Yoshida M, Igawa K, Sakoda S: Extensive necrosis of pleomorphic adenoma in the soft palate: a case report and review of the literature. J Oral Maxillofac Surg; 2008 Apr;66(4):797-800
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  • [Title] Extensive necrosis of pleomorphic adenoma in the soft palate: a case report and review of the literature.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Palatal Neoplasms / pathology. Palate, Soft / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands, Minor / pathology

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  • (PMID = 18355608.001).
  • [ISSN] 1531-5053
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 10
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22. Manjunatha BS, Pateel GS, Shah V: Oral fibrolipoma-a rare histological entity: report of 3 cases and review of literature. J Dent (Tehran); 2010;7(4):226-31
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  • Lipomas are rare benign soft tissue mesenchymal neoplasms in the oral cavity, representing 1% of all benign oral tumors.
  • To the best of our knowledge a review of the English literature showed 33 cases of FL affecting the oral cavity.The diagnosis and differentiation of FL with clinically similar lesions such as fibroma, mucocele and pleomorphic adenoma are very essential for a correct treatment plan and complete follow-up.

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  • (PMID = 21998799.001).
  • [ISSN] 2008-2185
  • [Journal-full-title] Journal of dentistry (Tehran, Iran)
  • [ISO-abbreviation] J Dent (Tehran)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Iran
  • [Other-IDs] NLM/ PMC3184759
  • [Keywords] NOTNLM ; Adipocytes / Adipose Tissue Neoplasms / Buccal Mucosa / Lipoma
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23. Kerimoglu U, Aydingoz U, Ozkaya O, Aksu AE, Ergen FB: MRI of a benign chondroid syringoma. Br J Radiol; 2006 Aug;79(944):e59-61
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  • [Title] MRI of a benign chondroid syringoma.
  • Chondroid syringoma, also known as mixed tumour of the skin, is a relatively rare, usually benign tumour.
  • A few malignant cases, especially in the lower extremities, have been published, but most of them behave in a benign fashion.
  • A case of a middle-aged woman with surgically proved chondroid syringoma in the pretibial region is presented in this report with MRI and histological findings.
  • Despite rapid growth over a short period of time and a location reportedly associated with malignancy, the histological features were benign.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Sweat Gland Neoplasms / diagnosis

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  • (PMID = 16861320.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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24. Cho NP, Han HS, Soh Y, Son HJ: Overexpression of cyclooxygenase-2 correlates with cytoplasmic HuR expression in salivary mucoepidermoid carcinoma but not in pleomorphic adenoma. J Oral Pathol Med; 2007 May;36(5):297-303
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  • [Title] Overexpression of cyclooxygenase-2 correlates with cytoplasmic HuR expression in salivary mucoepidermoid carcinoma but not in pleomorphic adenoma.
  • Although COX-2 expression has been shown to be up-regulated in carcinomas of the salivary gland, its mechanisms are not completely understood.
  • METHODS: The expression of COX-2 and HuR was determined by immunohistochemistry in 28 cases of salivary pleomorphic adenoma and 18 cases of salivary mucoepidermoid carcinoma.
  • RESULTS: 28.6% and 72.2% of the pleomorphic adenomas and mucoepidermoid carcinomas showed high COX-2 expression respectively.
  • 35.7% of pleomorphic adenomas and 72.2% of mucoepidermoid carcinomas were tested positive for HuR in the cytoplasm of tumor cells.
  • There was a correlation between a high COX-2 immunoreactivity and cytoplasmic HuR expression in mucoepidermoid carcinomas but not in pleomorphic adenomas.
  • CONCLUSION: This study suggests that cytoplasmic HuR is correlated with COX-2 expression in salivary mucoepidermoid carcinomas.
  • In addition, the immunoreactivity of COX-2 and cytoplasmic HuR might be used to evaluate the nature of a borderline malignancy in the salivary glands.
  • [MeSH-major] Adenoma, Pleomorphic / metabolism. Antigens, Surface / metabolism. Carcinoma, Mucoepidermoid / metabolism. Cyclooxygenase 2 / metabolism. Neoplasm Proteins / metabolism. RNA-Binding Proteins / metabolism. Salivary Gland Neoplasms / metabolism

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  • (PMID = 17448140.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, Surface; 0 / ELAV Proteins; 0 / ELAV-Like Protein 1; 0 / ELAVL1 protein, human; 0 / Neoplasm Proteins; 0 / RNA-Binding Proteins; EC 1.14.99.1 / Cyclooxygenase 2
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25. Villalón G, Monteagudo C, Martín JM, Ramón D, Alonso V, Jordá E: [Chondroid syringoma: a clinical and histological review of eight cases]. Actas Dermosifiliogr; 2006 Nov;97(9):573-7
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  • [Title] [Chondroid syringoma: a clinical and histological review of eight cases].
  • [Transliterated title] Siringoma condroide: revisión clínica e histológica de ocho casos.
  • INTRODUCTION: Chondroid syringoma is a rare skin tumor that presents as a slow growing, indolent lesion, that is more frequent in male adults and is usually benign.
  • MATERIAL AND METHODS: Eight cases diagnosed of chondroid syringoma in our Department in the last eight years were reevaluated clinically and histologically and the epiluminiscence microscopy was used in one of them.
  • All the cases had a myxoid matrix and most also had a chondroid one.
  • DISCUSSION: The chondroid syringoma is usually a small-sized skin tumor, frequently on the head and neck.
  • The microscopic examination of these lesions reveals tubuloalveolar and glandular type structures positioned as islets within a fibroadipose, chondroid, myxoid or hyaline stroma.
  • The final treatment of these tumors is surgical.
  • As a general rule, it is a benign tumor.
  • Some authors have proposed the term of atypical mixed tumor of the skin for those chondroid syringomas with histological traits of malignancy but without evidence of metastasis.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 17173760.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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26. Ogawa R, Akaishi S, Hyakusoku H: Differential and exclusive diagnosis of diseases that resemble keloids and hypertrophic scars. Ann Plast Surg; 2009 Jun;62(6):660-4
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  • Previous articles suggested the presence of various kinds of malignant tumors that resemble keloid or hypertrophic scar, including dermatofibrosarcoma protuberans, trichilemmal carcinoma, and keloidal basal cell carcinoma.
  • All tumors were benign: apocrine cystadenoma, adult-onset juvenile xanthogranuloma, mixed tumor, and chronic folliculitis.
  • (1) biopsy should be conducted in anomalous cases because malignant disease may be the original or secondary problem, (2) steroid injection should be performed only after careful consideration because malignancy or infections may be present, (3) careful differential diagnosis is particularly challenging in African-Americans because skin and tumor color are often similar, and (4) the presence of bacterial or fungal infection should be investigated.
  • [MeSH-minor] Adenoma, Pleomorphic / pathology. Adult. Cystadenoma / pathology. Diagnosis, Differential. Folliculitis / pathology. Humans. Male. Middle Aged. Sweat Gland Neoplasms / pathology. Xanthogranuloma, Juvenile / pathology. Young Adult

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  • (PMID = 19461281.001).
  • [ISSN] 1536-3708
  • [Journal-full-title] Annals of plastic surgery
  • [ISO-abbreviation] Ann Plast Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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27. Lambros MB, Simpson PT, Jones C, Natrajan R, Westbury C, Steele D, Savage K, Mackay A, Schmitt FC, Ashworth A, Reis-Filho JS: Unlocking pathology archives for molecular genetic studies: a reliable method to generate probes for chromogenic and fluorescent in situ hybridization. Lab Invest; 2006 Apr;86(4):398-408
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  • CISH provides a spatial distribution of gene copy number changes in tumour tissue and allows a direct correlation between copy number changes and the morphological features of neoplastic cells.
  • To demonstrate the reliability of the probes generated with this protocol, four strategies were employed: (i) probes mapping to cyclin D1 (CCND1) were generated and their performance was compared with that of a commercially available probe for the same gene in a series of 10 FFPETS of breast cancer samples of which five harboured CCND1 amplification;.
  • (ii) probes targeting cyclin-dependent kinase 4 were used to validate an amplification identified by microarray-based comparative genomic hybridization (aCGH) in a pleomorphic adenoma;.
  • [MeSH-minor] Adenoma, Pleomorphic / genetics. Adenoma, Pleomorphic / pathology. Biological Specimen Banks. Breast Neoplasms / genetics. Breast Neoplasms / pathology. Carcinoma, Ductal, Breast / genetics. Carcinoma, Ductal, Breast / pathology. Carcinoma, Lobular / genetics. Carcinoma, Lobular / pathology. Chromogenic Compounds. Chromosomes, Artificial, Bacterial. Female. Humans. Oligonucleotide Array Sequence Analysis. Paraffin Embedding. Salivary Gland Neoplasms / genetics. Salivary Gland Neoplasms / pathology. Sensitivity and Specificity. Tissue Fixation. Translocation, Genetic

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  • (PMID = 16446704.001).
  • [ISSN] 0023-6837
  • [Journal-full-title] Laboratory investigation; a journal of technical methods and pathology
  • [ISO-abbreviation] Lab. Invest.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Chromogenic Compounds; 0 / DNA Probes
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28. Laxmisha C, Thappa DM, Jayanthi S: Chondroid syringoma of the ear lobe. J Eur Acad Dermatol Venereol; 2007 Feb;21(2):276-7
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  • [Title] Chondroid syringoma of the ear lobe.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Carcinoma, Skin Appendage / diagnosis. Ear Neoplasms / diagnosis. Ear, External / pathology

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  • (PMID = 17243982.001).
  • [ISSN] 0926-9959
  • [Journal-full-title] Journal of the European Academy of Dermatology and Venereology : JEADV
  • [ISO-abbreviation] J Eur Acad Dermatol Venereol
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Netherlands
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29. Lourenço SV, Lima DM: Pleomorphic adenoma and adenoid cystic carcinoma: in vitro study of the impact of TGFbeta1 on the expression of integrins and cytoskeleton markers of cell differentiation. Int J Exp Pathol; 2007 Jun;88(3):191-8
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  • [Title] Pleomorphic adenoma and adenoid cystic carcinoma: in vitro study of the impact of TGFbeta1 on the expression of integrins and cytoskeleton markers of cell differentiation.
  • Pleomorphic adenoma (PA) and adenoid cystic carcinoma (ACC) are the commonest benign and malignant salivary gland tumours respectively.
  • PA cells showed increased expression of integrins and de novo expression of differentiation markers upon TGFbeta1 stimulation.
  • This may reflect important differences in the biological behaviour of benign and malignant cells.
  • [MeSH-major] Adenoma, Pleomorphic / metabolism. Carcinoma, Adenoid Cystic / metabolism. Integrins / metabolism. Parotid Neoplasms / metabolism. Transforming Growth Factor beta1 / pharmacology
  • [MeSH-minor] Adult. Antigens, CD29 / analysis. Antigens, CD29 / metabolism. Antigens, Differentiation / analysis. Cell Differentiation / drug effects. Cell Proliferation / drug effects. Cytoskeleton / metabolism. Enzyme-Linked Immunosorbent Assay / methods. Female. Fluorescent Antibody Technique. Humans. Integrin beta3 / analysis. Integrin beta3 / metabolism. Integrin beta4 / analysis. Integrin beta4 / metabolism. Middle Aged. Stimulation, Chemical. Tumor Cells, Cultured

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  • [Cites] Genes Dev. 2000 Mar 15;14(6):627-44 [10733523.001]
  • [Cites] Cancer Lett. 1996 Dec 3;109(1-2):91-9 [9020907.001]
  • [Cites] J Cell Sci. 2000 Oct;113 ( Pt 20):3563-71 [11017872.001]
  • [Cites] Cell. 2000 Oct 13;103(2):295-309 [11057902.001]
  • [Cites] Am J Physiol Cell Physiol. 2002 Apr;282(4):C873-84 [11880276.001]
  • [Cites] Fertil Steril. 2002 Jul;78(1):154-61 [12095506.001]
  • [Cites] Am J Pathol. 2002 Jul;161(1):3-6 [12107082.001]
  • [Cites] Am J Pathol. 2002 Jul;161(1):183-93 [12107103.001]
  • [Cites] J Orthop Res. 2002 Sep;20(5):1042-9 [12382972.001]
  • [Cites] Mol Biol Cell. 2003 Jan;14(1):54-66 [12529426.001]
  • [Cites] J Biol Chem. 2003 Apr 4;278(14):12384-9 [12531888.001]
  • [Cites] J Oral Pathol Med. 2003 May;32(5):305-9 [12694355.001]
  • [Cites] Mol Cell Proteomics. 2004 May;3(5):466-77 [14766930.001]
  • [Cites] J Oral Pathol Med. 2004 Oct;33(9):574-80 [15357679.001]
  • [Cites] J Biol Chem. 1989 Jan 5;264(1):380-8 [2491849.001]
  • [Cites] Annu Rev Cell Biol. 1990;6:597-641 [2177343.001]
  • [Cites] J Biol Chem. 1991 Dec 5;266(34):23505-9 [1744142.001]
  • [Cites] Cell. 1992 Apr 3;69(1):11-25 [1555235.001]
  • [Cites] J Cell Biol. 1995 May;129(3):853-65 [7537276.001]
  • [Cites] Histopathology. 2000 Aug;37(2):118-23 [10931234.001]
  • (PMID = 17504449.001).
  • [ISSN] 0959-9673
  • [Journal-full-title] International journal of experimental pathology
  • [ISO-abbreviation] Int J Exp Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD29; 0 / Antigens, Differentiation; 0 / Integrin beta3; 0 / Integrin beta4; 0 / Integrins; 0 / Transforming Growth Factor beta1
  • [Other-IDs] NLM/ PMC2517303
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30. Kebebew F, Kotisso B: A rare case of squamous cell ex-pleomorphic adenoma of the submandibular salivary gland. Ethiop Med J; 2008 Oct;46(4):415-8
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  • [Title] A rare case of squamous cell ex-pleomorphic adenoma of the submandibular salivary gland.
  • We herein report a case of Carcinoma ex pleomorphic adenoma, a rare neoplasm of the submandibular salivary gland.
  • Histopathologic study confirmed squamous cell ex pleomorphic adenoma of the submandibular salivary gland.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Submandibular Gland Neoplasms / pathology

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  • (PMID = 19271409.001).
  • [ISSN] 0014-1755
  • [Journal-full-title] Ethiopian medical journal
  • [ISO-abbreviation] Ethiop. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ethiopia
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31. Schmutzhard J, Schwentner IM, Andrle J, Gunkel AR, Sprinzl GM: Resection of accessory parotid gland tumors through a peroral approach with facial nerve monitoring. J Craniofac Surg; 2007 Nov;18(6):1419-21
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  • [Title] Resection of accessory parotid gland tumors through a peroral approach with facial nerve monitoring.
  • Pathologic alterations, which occur in these tissues, are related to those found in the parotid gland.
  • In this report, we give an account of a minimally invasive surgical alternative through a peroral approach with facial nerve monitoring.
  • The histologically secured pleomorphic adenoma was completely removed.
  • We are confident that the peroral resection, supported by active and passive facial nerve monitoring, is a discussable alternative for well-selected tumors of accessory parotid glands.
  • [MeSH-major] Adenoma, Pleomorphic / surgery. Facial Nerve. Monitoring, Intraoperative. Oral Surgical Procedures / methods. Parotid Neoplasms / surgery

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  • (PMID = 17993893.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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32. Gaissert HA, Mark EJ: Tracheobronchial gland tumors. Cancer Control; 2006 Oct;13(4):286-94
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  • [Title] Tracheobronchial gland tumors.
  • BACKGROUND: Tracheal tumors are uncommon, making up only 0.2% of all respiratory malignancies in the United States.
  • Bronchial gland tumors demonstrate oncologic diversity and include benign, low-grade, and high-grade malignant tumors.
  • METHODS: We reviewed the present knowledge of bronchial gland tumors of the trachea, carina, and bronchi, including the epidemiology, presentation, evaluation, tumor types, and treatment options.
  • RESULTS: The malignant bronchial gland tumors, adenoid cystic carcinoma and mucoepidermoid carcinoma, are far more common than benign mucinous cystadenoma or pleomorphic adenoma.
  • Complete resection of localized tumors has excellent long-term results in symptomatic benign tumors.
  • The disease-free survival after resection of malignant tumors is limited by distant metastasis and regional disease, while local recurrence is uncommon.
  • CONCLUSIONS: Expanding knowledge of diagnostic evaluation and surgical therapy can improve the long-term survival of patients with tracheobronchial gland tumors.
  • [MeSH-minor] Clinical Trials as Topic. Humans. Neoplasm Staging. Salivary Gland Neoplasms / pathology. Salivary Gland Neoplasms / therapy. Thoracic Surgical Procedures. United States / epidemiology

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  • (PMID = 17075566.001).
  • [ISSN] 1073-2748
  • [Journal-full-title] Cancer control : journal of the Moffitt Cancer Center
  • [ISO-abbreviation] Cancer Control
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 49
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33. Yilmaz AD, Unlü E, Orbay H, Sensöz O: Giant pleomorphic adenoma of soft palate leading to obstruction of the nasopharyngeal port. J Craniofac Surg; 2006 Sep;17(5):1001-4
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  • [Title] Giant pleomorphic adenoma of soft palate leading to obstruction of the nasopharyngeal port.
  • Pleomorphic adenoma is the most common tumor of minor salivary glands, but it is rarely located in the soft palate.
  • In this paper, we present a case of an unusually large pleomorphic adenoma of the soft palate leading to snoring and hypernasal speech.
  • [MeSH-major] Adenoma, Pleomorphic / surgery. Palate, Soft / surgery. Salivary Gland Neoplasms / surgery

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  • (PMID = 17003633.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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34. De Backer A, Madern GC, Hakvoort-Cammel FG, Haentjens P, Oosterhuis JW, Hazebroek FW: Study of the factors associated with recurrence in children with sacrococcygeal teratoma. J Pediatr Surg; 2006 Jan;41(1):173-81; discussion 173-81
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  • PURPOSE: The aim of this study was to explore effects of (1) histological involvement of resection margins with microscopic residue, (2) incomplete removal of coccyx, and (3) tumor spillage on recurrence and on survival in children operated upon for sacrococcygeal teratoma (SCT).
  • Thirty-six percent of tumors were Altman type I, 27% type II, 18% type III, and 18% type IV.
  • Histologically, mature teratoma was observed in 48 patients, immature teratoma in 11, yolk sac tumor (YST) in 9, embryonal carcinoma in one, and mixed tumor in one.
  • Tumor recurrence was observed in 5 patients, 2 of whom died.
  • Of 2 patients with initially immature teratoma grade I, one relapsed with a benign lesion and one with YST leading to death.
  • Histological analysis of resection margins showed tumoral involvement in 11 patients (and also in one patient after resection of a recurrent tumor).
  • Intraoperative tumor spillage presented in 2 patients, who both died of metastatic disease.
  • One of 5 patients whose coccyx had not been removed died of metastatic disease.
  • One with immature teratoma developed a benign recurrent tumor.
  • Spillage of cyst fluid was never associated with recurrence, unlike spillage of tumor and absence of removal of coccyx.

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  • (PMID = 16410129.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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35. Zhang QQ, Song XC, Zhang H: [Resection of the pleomorphic adenoma in trachea by tracheotomy (Report of 2 cases).]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2009 Dec;44(12):1039
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  • [Title] [Resection of the pleomorphic adenoma in trachea by tracheotomy (Report of 2 cases).].
  • [MeSH-major] Adenoma, Pleomorphic. Tracheotomy

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  • (PMID = 20193623.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] Journal Article
  • [Publication-country] China
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36. Zhu X, Li C, Sun X, Mao Y, Li G, Liu X, Zhang Y, Qiu X: Immunoglobulin mRNA and protein expression in human oral epithelial tumor cells. Appl Immunohistochem Mol Morphol; 2008 May;16(3):232-8
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  • [Title] Immunoglobulin mRNA and protein expression in human oral epithelial tumor cells.
  • In the present study, we extended our investigation to study the frequencies of expression of IgG and IgA in some types of oral epithelial tumor cells, and analyzed the oral tumor-derived V regions characteristic of Ig gamma chain gene transcripts by immunohistochemistry, in situ hybridization, laser capture microdissection-correlated reverse-transcription polymerase chain reaction, and sequencing.
  • IgG and IgA immunoreactivity was prominent in the cytoplasmic or plasma membrane or secretion of malignant cells, pleomorphic adenoma tumor cells, and some normal glandular epithelial cells or squamous cells adjacent to tumors.
  • More importantly, rearranged Ig gene transcripts were identified in these tumor cells, and in some normal glandular epithelial cells, the V-D-J region sequences revealed that IgG transcripts in 2 tested oral tumors were oligoclonal.
  • These results support that the phenomenon of Ig could also be expressed in oral cavity epithelial tumor cells.

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  • (PMID = 18301247.001).
  • [ISSN] 1533-4058
  • [Journal-full-title] Applied immunohistochemistry & molecular morphology : AIMM
  • [ISO-abbreviation] Appl. Immunohistochem. Mol. Morphol.
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Immunoglobulin A; 0 / Immunoglobulin G; 0 / RNA, Messenger
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37. Auluck A, Pai KM: In reply: Pleomorphic adenoma with extensive necrosis report of two cases. Oral Diseases 2004; 10: 54-59. Oral Dis; 2005 May;11(3):194
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  • [Title] In reply: Pleomorphic adenoma with extensive necrosis report of two cases. Oral Diseases 2004; 10: 54-59.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Palate / pathology. Salivary Gland Neoplasms / pathology

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  • [CommentOn] Oral Dis. 2004 Jan;10(1):54-9 [14996296.001]
  • (PMID = 15888114.001).
  • [ISSN] 1354-523X
  • [Journal-full-title] Oral diseases
  • [ISO-abbreviation] Oral Dis
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] Denmark
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38. Kawabata A, Okano K, Uchida K, Yamaguchi R, Hayashi T, Tateyama S: Co-localization of chondromodulin-I (ChM-I) and bone morphogenetic protein-6 (BMP-6) in myoepithelial cells of canine mammary tumors. J Vet Med Sci; 2005 Nov;67(11):1097-102
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  • [Title] Co-localization of chondromodulin-I (ChM-I) and bone morphogenetic protein-6 (BMP-6) in myoepithelial cells of canine mammary tumors.
  • To compare the roles of chondromodulin-I (ChM-I) and bone morphogenetic protein-6 (BMP-6) in ectopic mesenchymal tissue formation in canine mammary gland tumors, 33 tumors and 2 normal mammary glands were examined.
  • Immunohistochemical analysis revealed co-expression of ChM-I and BMP-6 in canine mammary tumors.
  • In mixed tumors, newly formed woven bone with ossified cartilage matrix was observed in 4/9 cases.
  • The immunoreactivity to ChM-I and BMP-6 of the interstitial myoepithelial cells in the myxomatous stroma varied in each focus of mixed tumors.
  • Similar findings were found in complex adenomas.
  • In simple adenomas, hyperplasic myoepithelial cells within the basement membrane showed moderate immunoreactivity to both markers.
  • Western blot analysis detected a 25 kDa band of ChM-I in fresh tissue samples from three mixed tumors.
  • Our results support the hypothesis that proliferating myoepithelial cells with ChM-I and BMP-6 expression play important roles in mesenchymal metaplasia in canine mammary tumors.

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  • (PMID = 16327219.001).
  • [ISSN] 0916-7250
  • [Journal-full-title] The Journal of veterinary medical science
  • [ISO-abbreviation] J. Vet. Med. Sci.
  • [Language] ENG
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Bone Morphogenetic Protein 6; 0 / Bone Morphogenetic Proteins; 0 / Proteins
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39. Witt RL: Minimally invasive surgery for parotid pleomorphic adenoma. Ear Nose Throat J; 2005 May;84(5):308, 310-1
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  • [Title] Minimally invasive surgery for parotid pleomorphic adenoma.
  • Compared with total parotidectomy and complete superficial parotidectomy for the removal of a parotid pleomorphic adenoma, partial superficial parotidectomy with dissection and preservation of the facial nerve--defined as the excision of a tumor with a 2-cm margin of normal parotid parenchyma except at the point where the tumor abuts the facial nerve--is associated with a lower incidence of transient facial nerve dysfunction, facial contour disfigurement, and subsequent Frey's syndrome.
  • The author hypothesized that the use of this procedure to remove a benign pleomorphic adenoma might result in even less morbidity (transient or permanent facial nerve dysfunction, facial contour disfigurement, Frey's syndrome, and hypoesthesia) without increasing the risk of recurrence if only a 1-cm margin of normal parotid parenchyma was removed and if the posterior branches of the great auricular nerve were preserved To test this hypothesis, the author conducted a retrospective study of 30 patients--15 who had undergone the standard partial procedure (2-cm margin with great auricular nerve sacrifice) and 15 who had undergone the modified version (1-cm margin with great auricular nerve preservation).
  • Although a 1-cm area of normal parotid parenchyma around a benign pleomorphic adenoma was a safe margin, it was no better than a 2-cm margin in terms ofmorbidity and recurrence.
  • [MeSH-major] Adenoma, Pleomorphic / surgery. Parotid Neoplasms / surgery

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  • (PMID = 15971755.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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40. Precetti FA, Prieto Mde C, Pietrantonio A, González B: [Mixed carcinoid-adenocarcinoma in transverse colon]. Acta Gastroenterol Latinoam; 2010 Dec;40(4):357-60
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  • [Title] [Mixed carcinoid-adenocarcinoma in transverse colon].
  • [Transliterated title] Tumor mixto carcinoide-adenocarcinoma de colon transverso.
  • The following case is a 69-year-old woman with a presumptive diagnosis of adenocarcinoma in transverse colon, which was diagnosed by pathology as a mixed carcinoid-adenocarcinoma tumor after surgery.
  • We have found very few cases published of this type of tumor in the colon (around 20) but not cases in the transverse colon.
  • We point out with particular consideration that, due to the lack of information related to the functional behaviour and clinical characteristics of these mixed tumors, more studies, analysis, follow-up and descriptions are necessary to perform future diagnosis and therapeutic procedures.
  • [MeSH-major] Adenocarcinoma / diagnosis. Carcinoid Tumor / diagnosis. Colon, Transverse / pathology. Colonic Neoplasms / diagnosis. Mixed Tumor, Malignant / diagnosis

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  • (PMID = 21381410.001).
  • [ISSN] 0300-9033
  • [Journal-full-title] Acta gastroenterologica Latinoamericana
  • [ISO-abbreviation] Acta Gastroenterol. Latinoam.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Argentina
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; U3P01618RT / Fluorouracil
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41. Sciarretta V, Pasquini E, Frank G, Modugno GC, Cantaroni C, Mazzatenta D, Farneti G: Endoscopic treatment of benign tumors of the nose and paranasal sinuses: a report of 33 cases. Am J Rhinol; 2006 Jan-Feb;20(1):64-71
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  • [Title] Endoscopic treatment of benign tumors of the nose and paranasal sinuses: a report of 33 cases.
  • BACKGROUND: The endoscopic approach can be used successfully for the treatment of benign tumors such as fibroosseous and vascular lesions, pleomorphic adenoma, glioma, meningioma, and schwannoma.
  • METHODS: Thirty-three patients diagnosed with benign tumors of the nasal cavity and paranasal sinuses and treated using an endoscopic approach were reviewed retrospectively.
  • The endoscopic approach was simple in 28 cases and associated with an external approach in 5 cases (because of an intracranial extension of the tumor in four patients and its location at the level of the anterior wall of the frontal sinus in the last case).
  • CONCLUSION: In selected cases, endoscopic surgery can be considered an effective treatment for the resection of benign tumors involving the sinonasal tract.

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  • (PMID = 16539297.001).
  • [ISSN] 1050-6586
  • [Journal-full-title] American journal of rhinology
  • [ISO-abbreviation] Am J Rhinol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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42. Pistorio V, Teggi R, Bussi M: Simultaneous pleomorphic adenoma of the parapharyngeal space and contralateral submandibular gland. Case report. Acta Otorhinolaryngol Ital; 2008 Oct;28(5):257-60
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  • [Title] Simultaneous pleomorphic adenoma of the parapharyngeal space and contralateral submandibular gland. Case report.
  • Herein the case is reported of a synchronous parapharyngeal space pleomorphic adenoma arising from the pharyngeal prolongation of the parotid gland and the contralateral submandibular gland, diagnosed in a young Caucasian female.
  • Palpating the left submandibular region, a painless, mobile, rounded mass, 10 mm in diameter, apparently located in the submandibular gland, was detected.
  • Cytological diagnosis was that of a typical pleomorphic adenoma.
  • To the best of our knowledge this is the second case report in the English literature of a concomitant pleomorphic adenoma located both in the parapharyngeal space and the submandibular gland.
  • [MeSH-major] Adenoma, Pleomorphic. Neoplasms, Multiple Primary. Parotid Neoplasms. Submandibular Gland Neoplasms

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  • [Cites] J Laryngol Otol. 1987 Jun;101(6):595-600 [3598361.001]
  • [Cites] Radiology. 1987 Apr;163(1):195-204 [3823435.001]
  • [Cites] J Pathol. 1985 May;146(1):51-8 [4009321.001]
  • [Cites] Am J Otolaryngol. 1985 Mar-Apr;6(2):92-7 [3993863.001]
  • [Cites] Ann Otol Rhinol Laryngol Suppl. 1981 Jan-Feb;90(1 Pt 4):3-15 [6258468.001]
  • [Cites] Diagn Cytopathol. 2005 Jan;32(1):11-5 [15584054.001]
  • [Cites] Ann Otol Rhinol Laryngol. 1959 Dec;68:1082-96 [13826893.001]
  • [Cites] J Oral Maxillofac Surg. 1998 Feb;56(2):272-6 [9461160.001]
  • [Cites] Head Neck. 1996 Jan-Feb;18(1):67-77 [8774924.001]
  • [Cites] Ann Otol Rhinol Laryngol. 1989 Apr;98(4 Pt 1):320-1 [2650597.001]
  • [Cites] Cancer. 1993 Oct 15;72(8):2306-11 [8402443.001]
  • [Cites] Clin Orthop Relat Res. 1994 Nov;(308):192-8 [7955683.001]
  • [Cites] Otolaryngol Head Neck Surg. 1995 Apr;112(4):612-5 [7700673.001]
  • [Cites] Head Neck. 1995 Mar-Apr;17(2):124-30 [7558809.001]
  • (PMID = 19186457.001).
  • [ISSN] 0392-100X
  • [Journal-full-title] Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale
  • [ISO-abbreviation] Acta Otorhinolaryngol Ital
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2689530
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43. Jakubowski M, Hunt JL: BRAF mutational analysis in papillary carcinomas with mixed follicular and papillary growth patterns. Am J Surg Pathol; 2009 Nov;33(11):1590-3
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  • [Title] BRAF mutational analysis in papillary carcinomas with mixed follicular and papillary growth patterns.
  • Tumors with mixed patterns of growth, including distinctive area of follicular and papillary growth, have not been well studied for the presence of the BRAF gene mutation.
  • The tumor stage was obtained, along with demographic information.
  • Seventy percent of the tumors were positive for the BRAF mutation.
  • These molecular data support the common diagnostic decision that a tumor with any amount of conventional papillary growth should be designated as a conventional papillary carcinoma, regardless of the presence of follicular growth pattern areas.

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  • (PMID = 19738460.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm; EC 2.7.11.1 / BRAF protein, human; EC 2.7.11.1 / Proto-Oncogene Proteins B-raf
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44. Kano H, Kondziolka D, Niranjan A, Flickinger JC, Lunsford LD: Stereotactic radiosurgery for pilocytic astrocytomas part 1: outcomes in adult patients. J Neurooncol; 2009 Nov;95(2):211-218
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  • Localized solid tumor progression was seen in two patients.
  • Cyst progression was noted in three of nine patients with cystic tumors and mixed solid and cyst progression was noted in two with cystic tumors.
  • The progression free survival after SRS (including tumor growth and cyst enlargement) for the entire series was 83.9%, 31.5% and 31.5% at 1, 3 and 5 years, respectively.
  • Despite their purported benign nature, pilocytic astrocytomas in adult patients often do not behave benignly.
  • Delayed cyst progression contributes to late loss of tumor control.

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  • [Cites] J Neurosurg. 2002 Jul;97(1):56-64 [12134933.001]
  • [Cites] Cancer. 1993 Aug 15;72(4):1335-42 [8339223.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1990 Apr;18(4):971-3 [2323983.001]
  • [Cites] J Neurosurg. 1973 Dec;39(6):777-9 [4759666.001]
  • [Cites] J Neurooncol. 2006 Jan;76(1):55-8 [16132503.001]
  • [Cites] Br J Neurosurg. 2004 Dec;18(6):613-6 [15799194.001]
  • [Cites] Br J Ophthalmol. 1969 Dec;53(12):793-8 [5386369.001]
  • [Cites] J Neurosurg. 2003 Jun;98(6):1170-4 [12816259.001]
  • [Cites] Cancer. 1985 Oct 1;56(7 Suppl):1841-6 [4027923.001]
  • [Cites] J Neurosurg. 2002 Dec;97(5 Suppl):677-80 [12507119.001]
  • [Cites] Cancer. 2007 Dec 15;110(12 ):2799-808 [17973253.001]
  • [Cites] Pediatr Neurosurg. 1996 Sep;25(3):109-15 [9144708.001]
  • [Cites] Neurosurgery. 1994 Jan;34(1):68-78 [8121571.001]
  • [Cites] Acta Neurochir (Wien). 1986;81(1-2):11-26 [3728086.001]
  • [Cites] Neurosurgery. 1990 Feb;26(2):242-6; discussion 246-7 [2308672.001]
  • [Cites] Neurosurg Rev. 1990;13(4):315-20 [2280843.001]
  • [Cites] Arch Neurol. 1968 Jan;18(1):14-9 [5634368.001]
  • [Cites] J Neurosurg. 1985 Sep;63(3):382-6 [4020465.001]
  • [Cites] Acta Neurochir (Wien). 1986;81(3-4):90-3 [3751698.001]
  • [Cites] Arch Neurol. 1971 Feb;24(2):125-35 [5540377.001]
  • [Cites] Radiology. 1993 Oct;189(1):221-5 [8372197.001]
  • [Cites] Neuro Oncol. 2007 Apr;9(2):161-8 [17347491.001]
  • [Cites] Neurosurgery. 1993 Dec;33(6):964-71 [8134009.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2004 Mar 15;58(4):1153-60 [15001258.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1990 Apr;18(4):815-8 [2323970.001]
  • [Cites] Cancer. 1993 Aug 1;72(3):856-69 [8334640.001]
  • [Cites] Pediatr Neurosurg. 1990-1991;16(4-5):219-21 [2135190.001]
  • [Cites] Childs Brain. 1983;10(2):79-91 [6839871.001]
  • (PMID = 19468691.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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45. Gütgemann I, Lehman NL, Jackson PK, Longacre TA: Emi1 protein accumulation implicates misregulation of the anaphase promoting complex/cyclosome pathway in ovarian clear cell carcinoma. Mod Pathol; 2008 Apr;21(4):445-54
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  • Clear cell carcinoma is a clinically and pathologically distinct entity among surface epithelial ovarian neoplasms, recognized for its resistance to standard platinum-based chemotherapy at advanced stage disease and poor prognosis.
  • We investigated Emi1 protein expression in ovarian neoplasms using a tissue microarray constructed from 339 primary ovarian surface epithelial (serous, endometrioid, clear cell, and mucinous) and peritoneal (serous) neoplasms, stromal and mesenchymal tumors, germ cell tumors, and normal ovarian tissue.
  • Significant overexpression of Emi1 protein was present in 82% (27/33) clear cell carcinoma, including one borderline tumor in a diffuse, granular cytoplasmic and perinuclear staining pattern, independent of patient age, presence of ovarian and/or pelvic endometriosis, and FIGO stage.
  • Emi1 protein expression was present in mixed endometrioid/clear cell tumors but absent in tumors with mixed serous/clear cell histology.

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  • (PMID = 18204430.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cell Cycle Proteins; 0 / Cyclin E; 0 / F-Box Proteins; 0 / FBXO5 protein, human; 0 / Ki-67 Antigen; 0 / Receptors, Estrogen; EC 6.3.2.19 / Anaphase-Promoting Complex-Cyclosome; EC 6.3.2.19 / Ubiquitin-Protein Ligase Complexes
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46. Peersman B, Vanhoenacker FM, Heyman S, Van Herendael B, Stam M, Brys P, Verstraete KL, Samson I, Sybers J, Van Dyck P, Parizel PM, De Schepper AM: Ewing's sarcoma: imaging features. JBR-BTR; 2007 Sep-Oct;90(5):368-76
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  • MATERIALS AND METHODS: Sixty-four patients with a histopathologically and/or genetically proven diagnosis of ES were analyzed for clinical parameters (age, gender and location), radiographic and CT appearance (distribution, matrix, margins, periosteal reaction, articular extension, cortical reaction and the presence of a pathologic fracture).
  • Most tumors were mixed lytic-sclerotic (75%), and purely lytic in 25%.
  • ES is mostly mixed sclerotic-lytic.
  • The most characteristic finding on MRI is the presence of a large soft tissue mass.

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  • (PMID = 18085191.001).
  • [ISSN] 0302-7430
  • [Journal-full-title] JBR-BTR : organe de la Société royale belge de radiologie (SRBR) = orgaan van de Koninklijke Belgische Vereniging voor Radiologie (KBVR)
  • [ISO-abbreviation] JBR-BTR
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Belgium
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47. Ryska A: [What is your diagnosis? Answer: Noninvasive (intracapsular) carcinoma in pleomorphic adenoma]. Cesk Patol; 2008 Jul;44(3):79, 85
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  • [Title] [What is your diagnosis? Answer: Noninvasive (intracapsular) carcinoma in pleomorphic adenoma].
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Carcinoma / pathology. Salivary Gland Neoplasms / pathology

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  • (PMID = 18783140.001).
  • [ISSN] 1210-7875
  • [Journal-full-title] Československá patologie
  • [ISO-abbreviation] Cesk Patol
  • [Language] cze
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Czech Republic
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48. Baek CH, Jeong HS: Endoscope-assisted submandibular sialadenectomy: a new minimally invasive approach to the submandibular gland. Am J Otolaryngol; 2006 Sep-Oct;27(5):306-9
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  • [Title] Endoscope-assisted submandibular sialadenectomy: a new minimally invasive approach to the submandibular gland.
  • MATERIALS AND METHODS: We performed EASS on 5 patients, 3 of whom had intraparenchymal sialolithiasis and 2 of whom had pleomorphic adenomas.
  • [MeSH-major] Adenoma, Pleomorphic / surgery. Endoscopy / methods. Salivary Gland Calculi / surgery. Submandibular Gland / surgery. Submandibular Gland Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Cranial Nerve Diseases / etiology. Cranial Nerve Diseases / prevention & control. Feasibility Studies. Female. Humans. Lingual Nerve / physiopathology. Male. Minimally Invasive Surgical Procedures. Submandibular Gland Diseases / complications. Tissue Adhesions / complications. Treatment Outcome

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  • (PMID = 16935172.001).
  • [ISSN] 0196-0709
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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49. Dubb M, Michelow P: Cytologic features of chondroid syringoma in fine needle aspiration biopsies: a report of 3 cases. Acta Cytol; 2010 Mar-Apr;54(2):183-6
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  • [Title] Cytologic features of chondroid syringoma in fine needle aspiration biopsies: a report of 3 cases.
  • However, most clinicians prefer to diagnose suspected skin tumors by excisional biopsy as they are easily accessible, with the result that benign skin adnexal tumors are rarely encountered on FNA, often leading to misdiagnosis and mismanagement of patients.
  • We describe the cytologic features of chondroid syringoma in 3 cases in order to facilitate cytologic diagnosis of this lesion.
  • CASES: Three patients each presented with a mass lesion in the head and neck region and on FNA were diagnosed as having chondroid syringomas.
  • CONCLUSION: Knowledge of the cytologic features of chondroid syringoma will allow definitive diagnosis and correct management of the patient.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Salivary Gland Neoplasms / diagnosis

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  • (PMID = 20391975.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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50. Rodríguez-Fernández J, Mateos-Micas M, Martínez-Tello FJ, Berjón J, Montalvo JJ, Forteza-González G, Galan-Hernández R: Metastatic benign pleomorphic adenoma. Report of a case and review of the literature. Med Oral Patol Oral Cir Bucal; 2008 Mar;13(3):E193-6
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  • [Title] Metastatic benign pleomorphic adenoma. Report of a case and review of the literature.
  • Pleomorphic adenoma (PA), originally called mixed tumour, is the most common neoplasm of the salivary glands and is generally accepted as benign biologically.
  • The metastasis may develop in a PA in which a malignant transformation occurs, either arising a carcinoma in the PA (carcinoma ex-mixed tumour) or as a carcinosarcoma (so-called true malignant mixed tumour).
  • However, very rare benign PA eventually metastasise, usually after having a previous recurrence, displaying benign histological features as well in the primary tumour as in the metastasis.
  • These tumours have been termed metastatic PA or metastatic mixed tumours.
  • The aim of this paper is to report one case of metastatic histological benign pleomorphic adenoma, and to consider the clinical, pathological and therapeutic consequences of these rare tumours as well as its possible causes and mechanisms for its behaviour.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Lung Neoplasms / secondary. Salivary Gland Neoplasms / pathology

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  • (PMID = 18305442.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 29
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51. Tanno T, Tanaka Y, Sugiura T, Akiyoshi H, Takenaka S, Kuwamura M, Yamate J, Ohashi F, Kubo K, Tsuyama S: Expression patterns of the slit subfamily mRNA in canine malignant mammary tumors. J Vet Med Sci; 2006 Nov;68(11):1173-7
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  • [Title] Expression patterns of the slit subfamily mRNA in canine malignant mammary tumors.
  • In humans, slit2 protein attracts endothelial cells and promotes tube formation in the tumor angiogenic mechanism.
  • In this study, we cloned a part of the canine slit subfamily and examined the expression of slit subfamily mRNAs in 3 normal canine mammary glands and 11 mammary tumor samples by RT-PCR.
  • The mRNAs were expressed at low levels in the normal mammary gland.
  • The expression levels of slit1 mRNA were low in both the normal and tumor tissues.
  • In contrast, the expression of slit2 mRNA increased in most of the malignant mammary tumors, and an increase in slit3 mRNA expression was observed in 2 of the malignant mixed tumors.
  • These results suggest that the expression of slit2 plays an important role in tumor angiogenesis in canine mammary gland tumors and that slit2 can be a putative marker for malignancy diagnosis of these tumors.

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  • (PMID = 17146174.001).
  • [ISSN] 0916-7250
  • [Journal-full-title] The Journal of veterinary medical science
  • [ISO-abbreviation] J. Vet. Med. Sci.
  • [Language] ENG
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / DNA Primers; 0 / Glycoproteins; 0 / Nerve Tissue Proteins; 0 / RNA, Messenger; 0 / slit protein, vertebrate
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52. Sirohi D, Sharma R, Sinha R, Suresh Menon P: Salivary gland neoplasms: an analysis of 74 cases. J Maxillofac Oral Surg; 2009 Jun;8(2):164-6
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  • [Title] Salivary gland neoplasms: an analysis of 74 cases.
  • Between 2006 and 2009, 74 cases of salivary gland neoplasms were analyzed retrospectively, of which 44 (60%) were benign and 30 (40%) malignant.
  • 61 % percent of neoplasms were in the parotid gland, 22% in the minor salivary glands including sublingual salivary glands, and 17% in the submandibular glands.
  • The most common benign neoplasm was pleomorphic adenoma (64%), and the most common malignant neoplasm were adenoid cystic carcinoma (17%) and mucoepidermoid carcinoma (23%).
  • We analyze the incidence and distribution of all types of salivary gland neoplasms in our series, and provide data for comparison with other epidemiological studies from different geographical sites and races.
  • Demographic data from these studies help us to a better understanding of the biological and clinical characteristics of the disease.
  • Further epidemiological surveys should be encouraged for better understanding of the disease and to provide early and better treatment of salivary gland neoplasms.

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  • [Cites] J Craniomaxillofac Surg. 2000 Feb;28(1):56-61 [10851675.001]
  • [Cites] Int J Oral Maxillofac Surg. 2002 Jun;31(3):257-61 [12190130.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 2002 Dec;128(12):1400-3 [12479728.001]
  • [Cites] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Jul;104(1):94-100 [17577550.001]
  • [Cites] Br J Oral Maxillofac Surg. 2008 Dec;46(8):635-8 [18620785.001]
  • [Cites] Int J Oral Maxillofac Surg. 2003 Aug;32(4):373-7 [14505619.001]
  • [Cites] Indian J Cancer. 2001 Mar;38(1):38-45 [14758884.001]
  • [Cites] Int J Oral Maxillofac Surg. 2005 Jul;34(5):528-32 [16053873.001]
  • [Cites] Int J Oral Maxillofac Surg. 2005 Jul;34(5):533-6 [16053874.001]
  • [Cites] Int J Oral Maxillofac Surg. 2006 Feb;35(2):150-4 [16181771.001]
  • [Cites] Oral Dis. 2005 Nov;11(6):386-91 [16269031.001]
  • (PMID = 23139498.001).
  • [ISSN] 0972-8279
  • [Journal-full-title] Journal of maxillofacial and oral surgery
  • [ISO-abbreviation] J Maxillofac Oral Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3453927
  • [Keywords] NOTNLM ; Parotid / Pleomorphic adenoma / Sublingual / Submandibular / mucoepidermoid carcinoma
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53. Kinkor Z, Hes O: [Pleomorphic epithelioid/clear cell malignant tumor of the uterus exhibiting both myoid and melanocytic differentiation--leiomyosarcoma or PEComa? A case report and a review of the literature]. Cesk Patol; 2007 Jul;43(3):103-8
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  • [Title] [Pleomorphic epithelioid/clear cell malignant tumor of the uterus exhibiting both myoid and melanocytic differentiation--leiomyosarcoma or PEComa? A case report and a review of the literature].
  • [Transliterated title] Pleomorfni epiteloidni a svetlobunecný maligní tumor delohy s myoidní a melanocytární diferenciací--leiomyosarkom nebo PECom? Kazuistika a prehled literatury.
  • Microscopically, the tumor displayed solid mosaic pattern and consisted of large epithelioid cells with ample eosinophilic, finely granular cytoplasm ongoing apparent clear cell change elsewhere.
  • No obvious stigmata of tuberous sclerosis were found and a five months follow-up after chemotherapy indicated no progression of disease.
  • With some uncertainty the tumor was finally rendered as pleomorphic leiomyosarcoma with peculiar melanocytic differentiation.
  • Expressed are both difficulty in explaining the histogenesis and ambiguity of the existing terminology of the uterine tumors with mixed myoid and melanocytic phenotype.


54. Skálová A, Vanecek T, Sima R, Laco J, Weinreb I, Perez-Ordonez B, Starek I, Geierova M, Simpson RH, Passador-Santos F, Ryska A, Leivo I, Kinkor Z, Michal M: Mammary analogue secretory carcinoma of salivary glands, containing the ETV6-NTRK3 fusion gene: a hitherto undescribed salivary gland tumor entity. Am J Surg Pathol; 2010 May;34(5):599-608
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mammary analogue secretory carcinoma of salivary glands, containing the ETV6-NTRK3 fusion gene: a hitherto undescribed salivary gland tumor entity.
  • We present a series of 16 salivary gland tumors with histomorphologic and immunohistochemical features reminiscent of secretory carcinoma of the breast.
  • This is a hitherto undescribed and distinctive salivary gland neoplasm, with features resembling both salivary acinic cell carcinoma (AciCC) and low-grade cystadenocarcinoma, and displaying strong similarities to breast secretory carcinoma.
  • Microscopically, the tumors have a lobulated growth pattern and are composed of microcystic and glandular spaces with abundant eosinophilic homogenous or bubbly secretory material positive for periodic acid-Schiff, mucicarmine, MUC1, MUC4, and mammaglobin.
  • For this tumor, we propose a designation mammary analogue secretory carcinoma of salivary glands (MASC).
  • Thirteen cases occurred in the parotid gland, and one each in the minor salivary glands of the buccal mucosa, upper lip, and palate.
  • The mean size of the tumors was 2.1 cm (range 0.7 to 5.5 cm).
  • This translocation was not found in any conventional salivary AciCC (12 cases), nor in other tumor types including pleomorphic adenoma (1 case) and low-grade cribriform cystadenocarcinoma (1 case), whereas ETV6-NTRK3 gene rearrangements were proven in all 3 tested cases of mammary secretory carcinoma.
  • [MeSH-major] Cystadenocarcinoma / genetics. Oncogene Proteins, Fusion / genetics. Salivary Gland Neoplasms / genetics
  • [MeSH-minor] Adult. Aged. Biomarkers, Tumor / metabolism. Chromosomes, Human, Pair 12. Chromosomes, Human, Pair 15. Combined Modality Therapy. Female. Gene Rearrangement. Humans. Immunohistochemistry. In Situ Hybridization, Fluorescence. Male. Middle Aged. Neoplasms, Multiple Primary. RNA, Neoplasm / analysis. Reverse Transcriptase Polymerase Chain Reaction. Salivary Glands / surgery. Translocation, Genetic. Treatment Outcome. Young Adult

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  • [CommentIn] Am J Surg Pathol. 2011 Oct;35(10):1600-2 [21934478.001]
  • (PMID = 20410810.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / ETV6-NTRK3 fusion protein, human; 0 / Oncogene Proteins, Fusion; 0 / RNA, Neoplasm
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55. Alibek S, Zenk J, Bozzato A, Lell M, Grunewald M, Anders K, Rabe C, Iro H, Bautz W, Greess H: The value of dynamic MRI studies in parotid tumors. Acad Radiol; 2007 Jun;14(6):701-10
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  • [Title] The value of dynamic MRI studies in parotid tumors.
  • RATIONALE AND OBJECTIVES: To evaluate the ability of dynamic contrast-enhanced magnetic resonance imaging (MRI) to differentiate several tumor entities of the parotid gland in a prospective clinical trial.
  • MATERIALS AND METHODS: A total of 112 patients with parotid tumors were examined with dynamic contrast-enhanced 1.5 T MRI.
  • Signal intensity versus time (SIvT) curves was obtained for all tumors.
  • Finally, all MRIs together with the tumor specific SIvT curves were re-read and correlated with histopathologic diagnosis.
  • RESULTS: Four characteristic intensity-time curves were observed: pleomorphic adenoma showed a gradual increase in signal intensity, followed by a plateau phase on a low intensity level.
  • Statistic significance was found for the time-to-peak values for adenolymphomas and pleomorphic adenomas and for the maximum peak signal intensity values for carcinomas.
  • Together with other morphologic MRI criteria (contrast enhancement, border characteristics) and clinical features, a differentiation between adenolymphoma and carcinoma was possible.
  • CONCLUSIONS: With additional dynamic contrast-enhanced MRI, a more reliable differentiation between common parotid tumors is possible before surgery.
  • [MeSH-major] Adenolymphoma / diagnosis. Adenoma, Pleomorphic / diagnosis. Carcinoma / diagnosis. Magnetic Resonance Imaging / methods. Parotid Gland / pathology. Parotid Neoplasms / diagnosis

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  • (PMID = 17502260.001).
  • [ISSN] 1076-6332
  • [Journal-full-title] Academic radiology
  • [ISO-abbreviation] Acad Radiol
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; AU0V1LM3JT / Gadolinium
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56. Uruga H, Fujii T, Kurosaki A, Hanada S, Takaya H, Miyamoto A, Morokawa N, Kishi K: [A case of pulmonary tumor thrombotic microangiopathy caused by carcinoma (salivary duct carcinoma) ex pleomorphic adenoma]. Nihon Kokyuki Gakkai Zasshi; 2010 Jun;48(6):463-8
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  • [Title] [A case of pulmonary tumor thrombotic microangiopathy caused by carcinoma (salivary duct carcinoma) ex pleomorphic adenoma].
  • A 53-year-old man with carcinoma (salivary duct carcinoma) ex pleomorphic adenoma was admitted to our hospital because of dyspnea.
  • An autopsy was performed, and microscopic examination revealed tumor cell embolism, intimal fibrocellular proliferation of the small arteries, fibrin thrombi and recanalization.
  • A diagnosis of pulmonary tumor thrombotic microangiopathy (PTTM) was made.
  • Immunohistochemical staining of the tumor cells for VEGF was weakly positive.
  • To the best of our knowledge this is the first reported case of PTTM caused by a salivary gland tumor.
  • [MeSH-major] Carcinoma / complications. Lung Neoplasms / complications. Salivary Ducts. Salivary Gland Neoplasms / complications. Thrombotic Microangiopathies / etiology

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  • (PMID = 20608093.001).
  • [ISSN] 1343-3490
  • [Journal-full-title] Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
  • [ISO-abbreviation] Nihon Kokyuki Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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57. Nilsson M, Panagopoulos I, Mertens F, Mandahl N: Fusion of the HMGA2 and NFIB genes in lipoma. Virchows Arch; 2005 Nov;447(5):855-8
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  • In addition, subsets of other benign solid tumors show aberrations of 12q13-15.
  • Among pleomorphic adenomas of the salivary glands, where the preferred recombination partner with 12q13-15 is 9p22-24, an HMGA2/NFIB fusion gene has been reported.
  • It was identical to a transcript that was previously described in salivary gland adenoma and contained a stop codon shortly 3' of the fusion point.
  • The finding of the same fusion gene in different tumors is not unique.
  • For example, HMGA2/LPP has been reported in lipoma, pulmonary chondroid hamartoma, and soft tissue chondroma.
  • Since similar 9;12 translocations have been described also in rare cases of hamartoma and uterine leiomyoma, the occurrence of HMGA2/NFIB could be postulated in these tumors as well.

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  • [Cites] Eur J Obstet Gynecol Reprod Biol. 2003 Sep 10;110(1):58-62 [12932873.001]
  • [Cites] Cancer Genet Cytogenet. 1991 May;53(1):125-36 [2036633.001]
  • [Cites] Oncogene. 1998 Feb 19;16(7):865-72 [9484777.001]
  • [Cites] Cancer Genet Cytogenet. 2003 Jun;143(2):160-8 [12781451.001]
  • [Cites] Cytogenet Genome Res. 2006;112(1-2):60-6 [16276091.001]
  • [Cites] Genes Chromosomes Cancer. 1994 Mar;9(3):207-15 [7515663.001]
  • [Cites] Genes Chromosomes Cancer. 2000 Dec;29(4):363-6 [11066083.001]
  • [Cites] Int J Oncol. 2002 Aug;21(2):321-6 [12118328.001]
  • [Cites] Genomics. 1996 Aug 15;36(1):118-29 [8812423.001]
  • [Cites] Carcinogenesis. 2001 Oct;22(10):1583-91 [11576996.001]
  • [Cites] Mod Pathol. 2003 Nov;16(11):1132-40 [14614053.001]
  • [Cites] Cancer Genet Cytogenet. 1991 Aug;55(1):11-8 [1913597.001]
  • [Cites] Genomics. 1999 May 1;57(3):438-41 [10329012.001]
  • [Cites] Cancer Genet Cytogenet. 1997 May;95(1):9-15 [9140448.001]
  • [Cites] Genes Chromosomes Cancer. 1999 Oct;26(2):125-33 [10469450.001]
  • [Cites] Int J Cancer. 2001 Sep;93(6):769-72 [11519035.001]
  • (PMID = 16133369.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / DNA, Neoplasm; 0 / HMGA2 Protein; 0 / NFI Transcription Factors; 0 / NFIB protein, human
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58. Huang ZQ, Chen WL, Li HG, Li JS, Xu ZY, Lin ZY: Extracellular matrix metalloproteinase inducer expression in salivary gland tumors: a correlation with microvessel density. J Craniofac Surg; 2010 Nov;21(6):1855-60
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  • [Title] Extracellular matrix metalloproteinase inducer expression in salivary gland tumors: a correlation with microvessel density.
  • The purpose of this study was to investigate the expression pattern of extracellular matrix metalloproteinase inducer (EMMPRIN) as well as the correlation between EMMPRIN and microvessel density (MVD) in salivary gland tumors.
  • Extracellular matrix metalloproteinase inducer expression and MVD were examined immunohistochemically on paraffin-embedded tissue specimens from 95 patients with salivary gland tumors, who underwent surgical resection from 1998 to 2006.
  • Extracellular matrix metalloproteinase inducer expression in mucoepidermoid carcinomas and adenoid cystic carcinomas was significantly higher than in normal salivary gland tissues and pleomorphic adenomas (P < 0.05).
  • The MVD of mucoepidermoid carcinomas and adenoid cystic carcinomas was significantly higher compared with pleomorphic adenomas (P < 0.05).
  • Extracellular matrix metalloproteinase inducer mRNA expression in malignant salivary gland tumors was higher than that in pleomorphic adenomas (P < 0.05).
  • This study suggests that EMMPRIN expression is an important feature of malignant salivary gland tumors and can be used as a biologic marker to characterize salivary gland tumors.
  • Extracellular matrix metalloproteinase inducer is also a positive angiogenic factor in salivary gland tumors.
  • [MeSH-major] Antigens, CD147 / analysis. Antigens, Neoplasm / analysis. Microvessels / pathology. Salivary Gland Neoplasms / immunology
  • [MeSH-minor] Adenoma, Pleomorphic / blood supply. Adenoma, Pleomorphic / immunology. Angiogenesis Inducing Agents / analysis. Antigens, CD34 / analysis. Biomarkers, Tumor / analysis. Carcinoma, Adenoid Cystic / blood supply. Carcinoma, Adenoid Cystic / immunology. Carcinoma, Mucoepidermoid / blood supply. Carcinoma, Mucoepidermoid / immunology. Epithelium / blood supply. Epithelium / immunology. Humans. Immunohistochemistry. RNA, Messenger / analysis. Reverse Transcriptase Polymerase Chain Reaction. Salivary Ducts / blood supply. Salivary Ducts / immunology. Salivary Glands / blood supply. Salivary Glands / immunology

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  • (PMID = 21119439.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Angiogenesis Inducing Agents; 0 / Antigens, CD34; 0 / Antigens, Neoplasm; 0 / BSG protein, human; 0 / Biomarkers, Tumor; 0 / RNA, Messenger; 136894-56-9 / Antigens, CD147
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59. Somefun OA, Oyeneyin JO, Abdulkarrem FB, da Lilly-Tariah OB, Nimkur LT, Esan OO: Surgery of parotid gland tumours in lagos: a 12 year review. Niger Postgrad Med J; 2007 Mar;14(1):72-5
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  • [Title] Surgery of parotid gland tumours in lagos: a 12 year review.
  • BACKGROUND/AIM: Tumours of the parotid gland are not common.
  • Forty-two (72.4%) presented with firm preauricular swelling, 1.7% as dumb bell tumour and post surgical recurrence tumour respectively, 6.8% as tail of parotid tumour and 3.5% as bilateral disease.
  • Histological diagnosis confirmed 65.5% as pleomorphic adenoma, 20.72% as carcinomas of which adenoidcystic and mucoepidermoid tumours were the commonest,3.45% as lymphoma and 1.7% as Sjogrens syndrome, oxyphil and Warthins tumour respectively.
  • CONCLUSION: The commonest parotid salivary gland tumour requiring surgery is pleomorphic adenoma, presenting as a pre-auricular mass and the commonest post- surgical complication was facial nerve palsy involving the mandibular branch.
  • A good knowledge of the surgical anatomy of the gland, clinical behaviour and biologic nature of the tumours will ensure better surgical management.
  • [MeSH-major] Parotid Gland. Parotid Neoplasms
  • [MeSH-minor] Adenoma, Pleomorphic. Humans. Nigeria. Retrospective Studies

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  • (PMID = 17356597.001).
  • [ISSN] 1117-1936
  • [Journal-full-title] The Nigerian postgraduate medical journal
  • [ISO-abbreviation] Niger Postgrad Med J
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Nigeria
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60. Wang BB, Pan QH, Zhang YF, Xu YZ, Wu QG, Zhou FS, Yu GY, Sun KH, Peng X, Wu JG: [Application of fourier transform infrared spectroscopy to non-invasive detection of pleomorphic adenoma of salivary gland in vivo]. Guang Pu Xue Yu Guang Pu Fen Xi; 2007 Dec;27(12):2427-31
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  • [Title] [Application of fourier transform infrared spectroscopy to non-invasive detection of pleomorphic adenoma of salivary gland in vivo].
  • In the present work, 20 patients with salivary pleomorphic adenoma were recruited for FTIR spectroscopic measurement.
  • It was found that there were significant differences in the spectral features of the skin covering normal salivary gland, pleomorphic adenoma, and carcinoma change of pleomorphic adenoma, such as the changes in peak position, band shape and relative intensity of the bands in the ranges of 1000-1800 cm(-1) and 2800-3000 cm(-1).
  • Pathological diagnosis demonstrated that 2 of the 20 patients suffered actually carcinoma change of pleomorphic adenoma, which is in good agreement with the result of FTIR spectroscopicmeasurement.
  • FTIR spectroscopic m ethodsuggested that pleomorphic adenoma is the intermediate between normal salivary gland and carcinoma change of pleomorphic adenoma.
  • [MeSH-major] Adenoma, Pleomorphic / chemistry. Salivary Gland Neoplasms / chemistry. Spectroscopy, Fourier Transform Infrared / methods

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  • (PMID = 18330277.001).
  • [ISSN] 1000-0593
  • [Journal-full-title] Guang pu xue yu guang pu fen xi = Guang pu
  • [ISO-abbreviation] Guang Pu Xue Yu Guang Pu Fen Xi
  • [Language] chi
  • [Publication-type] Clinical Trial; English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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61. Gahine R, Sudarshan V, Hussain N, Krishnani C: Pleomorphic adenoma: A diagnostic pitfall in the diagnosis of salivary gland lesions on FNAC: Case reports with review of the literature. Cytojournal; 2010;7:17
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  • [Title] Pleomorphic adenoma: A diagnostic pitfall in the diagnosis of salivary gland lesions on FNAC: Case reports with review of the literature.
  • Fine needle aspiration cytology (FNAC) is commonly being used with increasing frequency for the pre-operative evaluation of salivary gland lesions.
  • The most frequent problems involve variations in the expected cytology of pleomorphic adenoma (PA).
  • Salivary gland FNACs performed at Pt.
  • As PA is the most common salivary gland neoplasm, it should always be considered and ruled out as the first differential in the diagnosis of salivary gland FNACs.
  • To document the same, we advocate liberal use of repeat aspirations with multiple sampling performed from different parts of the tumor.

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  • (PMID = 20976206.001).
  • [ISSN] 1742-6413
  • [Journal-full-title] CytoJournal
  • [ISO-abbreviation] Cytojournal
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2955342
  • [Keywords] NOTNLM ; FNA salivary gland / pitfalls of diagnosis / pleomorphic adenoma / variability of tumor morphology
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62. Beil CM, Keberle M: Oral and oropharyngeal tumors. Eur J Radiol; 2008 Jun;66(3):448-59
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  • [Title] Oral and oropharyngeal tumors.
  • There is a large variability of tumors and tumor-like lesions, which are located in the oral cavity and oropharynx.
  • But more than 90% of all tumors in this area are squamous cell carcinomas (SCCs).
  • About 10% of all oral and oropharyngeal tumors are benign.
  • Acquired lesions can be inflammatory (abscess) or neoplastic (pleomorphic adenoma and hemangioma).

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  • (PMID = 18457933.001).
  • [ISSN] 0720-048X
  • [Journal-full-title] European journal of radiology
  • [ISO-abbreviation] Eur J Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Contrast Media
  • [Number-of-references] 18
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63. Affolter A, Helmbrecht S, Finger S, Hörmann K, Götte K: Altered expression of cell cycle regulators p21, p27, and p53 in tumors of salivary glands and paranasal sinuses. Oncol Rep; 2005 Jun;13(6):1089-94
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  • [Title] Altered expression of cell cycle regulators p21, p27, and p53 in tumors of salivary glands and paranasal sinuses.
  • In several human tumors, a loss of these proteins is associated with poor clinical outcome.
  • The role of these cell cycle regulators in tumors of salivary gland and paranasal sinus origin is still unclear.
  • In this study it was intended to demonstrate and compare the expression of p21, p27, and p53 in benign and malignant tumors of salivary glands and paranasal sinuses.
  • Nine adenoid cystic carcinomas, 5 adenocarcinomas, 4 cylindrical cell carcinomas, as well as 30 pleomorphic adenomas and 26 inverted papillomas, were studied.
  • All malignant tumors turned out to be positive for p21 after performing TSA-IHC, although 72% of those samples had shown weak to negative protein levels in conventional immunostaining.
  • The study sheds new light upon the role of CIP/KIP protein family in tumors of salivary glands and paranasal sinuses.
  • Furthermore, it is the first description of p21 and p53 TSA-IHC in these tumor types.
  • [MeSH-major] Adenocarcinoma / metabolism. Carcinoma, Adenoid Cystic / metabolism. Cell Cycle Proteins / metabolism. Paranasal Sinus Neoplasms / metabolism. Paranasal Sinuses / metabolism. Salivary Gland Neoplasms / metabolism. Tumor Suppressor Protein p53 / metabolism. Tumor Suppressor Proteins / metabolism

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  • (PMID = 15870926.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / CDKN1A protein, human; 0 / Cell Cycle Proteins; 0 / Cyclin-Dependent Kinase Inhibitor p21; 0 / Tumor Suppressor Protein p53; 0 / Tumor Suppressor Proteins; 147604-94-2 / Cyclin-Dependent Kinase Inhibitor p27
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64. Miguita L, Martinez EF, de Araújo NS, de Araújo VC: FGF-2, TGFbeta-1, PDGF-A and respective receptors expression in pleomorphic adenoma myoepithelial cells: an in vivo and in vitro study. J Appl Oral Sci; 2010 Jan-Feb;18(1):83-91
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  • [Title] FGF-2, TGFbeta-1, PDGF-A and respective receptors expression in pleomorphic adenoma myoepithelial cells: an in vivo and in vitro study.
  • Myoepithelial cells have an important role in salivary gland tumor development, contributing to a low grade of aggressiveness of these tumors.
  • The importance of stromal cells and growth factors during tumor initiation and progression has been highlighted by recent literature.
  • Many tumors result from the alteration of paracrine growth factors pathways.
  • OBJECTIVES: This study evaluated the expression of fibroblast growth factor-2 (FGF-2), transforming growth factor beta-1 (TGFbeta-1), platelet-derived growth factor-A (PDGF-A) and their respective receptors (FGFR-1, FGFR-2, TGFbetaR-II and PDGFR-alpha) in myoepithelial cells from pleomorphic adenomas (PA) by in vivo and in vitro experiments.
  • Myoepithelial cells were obtained from explants of PA tumors provided by surgery from different donors.
  • CONCLUSIONS: These data suggested that FGF-2 compared to the other studied growth factors has an important role in PA benign myoepithelial cells, probably contributing to proliferation of these cells through the FGFR-1.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Fibroblast Growth Factor 2 / analysis. Platelet-Derived Growth Factor / analysis. Protein-Serine-Threonine Kinases / analysis. Receptor, Fibroblast Growth Factor, Type 1 / analysis. Receptor, Fibroblast Growth Factor, Type 2 / analysis. Receptor, Platelet-Derived Growth Factor alpha / analysis. Receptors, Transforming Growth Factor beta / analysis. Salivary Gland Neoplasms / pathology. Transforming Growth Factor beta1 / analysis

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  • [Cites] J Mammary Gland Biol Neoplasia. 2005 Jul;10(3):249-60 [16807804.001]
  • [Cites] J Oral Pathol Med. 2001 Aug;30(7):413-20 [11488419.001]
  • [Cites] Oral Oncol. 1999 Jan;35(1):98-104 [10211317.001]
  • [Cites] Exp Cell Res. 1993 Feb;204(2):247-59 [8440322.001]
  • [Cites] Exp Mol Pathol. 2003 Apr;74(2):113-22 [12710942.001]
  • [Cites] Hum Pathol. 2009 Mar;40(3):390-7 [18992915.001]
  • [Cites] Oral Oncol. 2006 Nov;42(10):1011-6 [16757205.001]
  • [Cites] EMBO J. 1990 May;9(5):1511-7 [2328724.001]
  • [Cites] DNA Cell Biol. 2007 Dec;26(12):811-26 [18021009.001]
  • [Cites] FEBS Lett. 2000 Feb 18;468(1):6-10 [10683430.001]
  • [Cites] J Biol Chem. 1997 Mar 14;272(11):7211-22 [9054417.001]
  • [Cites] Mech Ageing Dev. 2007 Jan;128(1):17-24 [17118424.001]
  • [Cites] Oncogene. 2000 Aug 3;19(33):3750-6 [10949929.001]
  • [Cites] J Immunol. 2002 Oct 1;169(7):3485-91 [12244137.001]
  • [Cites] Biomed Pharmacother. 1995;49(9):389-99 [8746075.001]
  • [Cites] Differentiation. 2006 Sep;74(7):349-64 [16916374.001]
  • [Cites] J Cell Sci. 1993 Sep;106 ( Pt 1):135-43 [8270619.001]
  • [Cites] Biochim Biophys Acta. 2007 Jan;1775(1):21-62 [16904831.001]
  • [Cites] Nat Genet. 2007 Jan;39(1):52-60 [17143286.001]
  • [Cites] BMC Genomics. 2007 Apr 11;8:98 [17425807.001]
  • [Cites] Bioessays. 1998 May;20(5):400-11 [9670813.001]
  • [Cites] PLoS Med. 2008 Jan 29;5(1):e19 [18232728.001]
  • [Cites] PLoS Biol. 2008 May 6;6(5):e108 [18462018.001]
  • [Cites] Trends Genet. 2004 Nov;20(11):563-9 [15475116.001]
  • [Cites] Mol Cancer Res. 2004 Nov;2(11):643-52 [15561780.001]
  • [Cites] J Oral Pathol Med. 1997 Jan;26(1):17-22 [9021547.001]
  • [Cites] Carcinogenesis. 2008 Dec;29(12):2341-6 [18845558.001]
  • [Cites] Cytokine Growth Factor Rev. 2005 Apr;16(2):159-78 [15863032.001]
  • [Cites] Proc Natl Acad Sci U S A. 2003 Jul 8;100(14 ):8430-5 [12808151.001]
  • [Cites] Med Hypotheses. 1997 Jan;48(1):37-46 [9049988.001]
  • [Cites] Cytokine Growth Factor Rev. 2005 Apr;16(2):179-86 [15863033.001]
  • [Cites] Miner Electrolyte Metab. 1998;24(2-3):111-9 [9525693.001]
  • [Cites] Differentiation. 2007 Nov;75(9):831-42 [17697126.001]
  • [Cites] J Cell Biol. 2001 Mar 19;152(6):1307-12 [11257130.001]
  • [Cites] Oncologist. 2001;6 Suppl 5:4-7 [11700386.001]
  • [Cites] Mayo Clin Proc. 2006 Sep;81(9):1241-57 [16970222.001]
  • [Cites] Nature. 2004 Nov 18;432(7015):332-7 [15549095.001]
  • [Cites] Physiol Rev. 1999 Oct;79(4):1283-316 [10508235.001]
  • [Cites] Exp Cell Res. 2000 Jul 10;258(1):121-34 [10912794.001]
  • [Cites] J Oral Pathol Med. 1998 Aug;27(7):287-92 [9725564.001]
  • [Cites] J Oral Pathol Med. 2001 Mar;30(3):159-67 [11271631.001]
  • [Cites] Traffic. 2005 Oct;6(10):947-54 [16138907.001]
  • [Cites] FEBS J. 2008 Apr;275(7):1579-92 [18312416.001]
  • [Cites] Urology. 2000 Jun;55(6):800-6 [10840080.001]
  • [Cites] Genome Biol. 2001;2(3):REVIEWS3005 [11276432.001]
  • [Cites] Biochem Biophys Res Commun. 2000 Nov 2;277(3):643-9 [11062007.001]
  • [Cites] J Cell Mol Med. 2007 Nov-Dec;11(6):1239-50 [18205698.001]
  • [Cites] J Pathol. 1996 Apr;178(4):429-36 [8691322.001]
  • (PMID = 20379686.001).
  • [ISSN] 1678-7765
  • [Journal-full-title] Journal of applied oral science : revista FOB
  • [ISO-abbreviation] J Appl Oral Sci
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Brazil
  • [Chemical-registry-number] 0 / Actins; 0 / Calcium-Binding Proteins; 0 / Keratin-7; 0 / Microfilament Proteins; 0 / Muscle Proteins; 0 / Platelet-Derived Growth Factor; 0 / Receptors, Transforming Growth Factor beta; 0 / Transforming Growth Factor beta1; 0 / Vimentin; 0 / calponin; 0 / platelet-derived growth factor A; 103107-01-3 / Fibroblast Growth Factor 2; EC 2.7.10.1 / FGFR1 protein, human; EC 2.7.10.1 / FGFR2 protein, human; EC 2.7.10.1 / Receptor, Fibroblast Growth Factor, Type 1; EC 2.7.10.1 / Receptor, Fibroblast Growth Factor, Type 2; EC 2.7.10.1 / Receptor, Platelet-Derived Growth Factor alpha; EC 2.7.11.1 / Protein-Serine-Threonine Kinases; EC 2.7.11.30 / transforming growth factor-beta type II receptor
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65. Vyrupaev SV: [Treatment of giant tumors of the parotid gland]. Vopr Onkol; 2005;51(1):128-30
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  • [Title] [Treatment of giant tumors of the parotid gland].
  • Since large (<<giant>>) benign mixed tumors of the parotid gland are rare, there is insufficient evidence on the modalities of the facial nerve management.
  • Eight patients, aged 29-65, with tumors of more than 15 cm in diameter were operated on.
  • Tumors were located externally of the gland (5), parapharyngeally (2), or both (1).
  • The regularities between the facial nerve location and site of tumor were investigated, and it is suggested that, in difficult cases, search should start from the temporal area since it offers most access.
  • When tumor of parapharyngeal localization is excised, it is desirable to perform double osteotomy in the mental part of the mandible as well as at the point of entry of the lower of the alveolar nerve, to avoid the latter's being traumatized.
  • [MeSH-major] Parotid Gland / pathology. Salivary Gland Neoplasms / surgery

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  • (PMID = 15909823.001).
  • [ISSN] 0507-3758
  • [Journal-full-title] Voprosy onkologii
  • [ISO-abbreviation] Vopr Onkol
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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66. Jeffcoat BT, Pitman KT, Brown AS, Baliga M: Schwannoma of the oral tongue. Laryngoscope; 2010;120 Suppl 4:S154
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  • OBJECTIVE: To present a rare, benign lesion of the oral tongue and its treatment.
  • Fine needle aspiration was consistent with pleomorphic adenoma versus myoepithelioma.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Neurilemmoma / pathology. Tongue Neoplasms / pathology

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  • (PMID = 21225752.001).
  • [ISSN] 1531-4995
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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67. Bellizzi AM, Mills SE: Collagenous crystalloids in myoepithelial carcinoma: report of a case and review of the literature. Am J Clin Pathol; 2008 Sep;130(3):355-62
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  • [Title] Collagenous crystalloids in myoepithelial carcinoma: report of a case and review of the literature.
  • Since the first report of "tyrosine crystals" in a parotid mixed tumor by Bullock in 1953, authors have described several types of crystalloids in association with mixed tumor and related neoplastic and nonneoplastic entities.
  • We report a myoepithelial carcinoma of minor salivary gland origin containing numerous collagenous crystalloids.
  • In addition, we searched our institution's files for cases of pure myoepithelial tumors.
  • We review the literature on salivary-related crystalloids, and we propose the term oncocyte/cyst-associated crystalloids to encompass the aforementioned third class of crystalloid.
  • Given distinct morphologic and histochemical properties and given relatively limited disease associations, we conclude that in the appropriate clinical context, the identification of these crystalloids can be diagnostically useful.
  • [MeSH-major] Collagen / metabolism. Salivary Gland Neoplasms / pathology

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  • (PMID = 18701407.001).
  • [ISSN] 0002-9173
  • [Journal-full-title] American journal of clinical pathology
  • [ISO-abbreviation] Am. J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 9007-34-5 / Collagen
  • [Number-of-references] 31
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68. Lönn S, Ahlbom A, Christensen HC, Johansen C, Schüz J, Edström S, Henriksson G, Lundgren J, Wennerberg J, Feychting M: Mobile phone use and risk of parotid gland tumor. Am J Epidemiol; 2006 Oct 1;164(7):637-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mobile phone use and risk of parotid gland tumor.
  • This makes the Danish and Swedish populations suitable for a study aimed at testing the hypothesis that long-term mobile phone use increases the risk of parotid gland tumors.
  • In this population-based case-control study, the authors identified all cases aged 20-69 years diagnosed with parotid gland tumor during 2000-2002 in Denmark and certain parts of Sweden.
  • Detailed information about mobile phone use was collected from 60 cases of malignant parotid gland tumors (85% response rate), 112 benign pleomorphic adenomas (88% response rate), and 681 controls (70% response rate).
  • For regular mobile phone use, regardless of duration, the risk estimates for malignant and benign tumors were 0.7 (95% confidence interval: 0.4, 1.3) and 0.9 (95% confidence interval: 0.5, 1.5), respectively.
  • The risk estimate did not increase, regardless of type of phone and amount of use.
  • The authors conclude that the data do not support the hypothesis that mobile phone use is related to an increased risk of parotid gland tumors.

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  • [CommentIn] Am J Epidemiol. 2007 Jan 15;165(2):231; author reply 231 [17148495.001]
  • (PMID = 16818464.001).
  • [ISSN] 0002-9262
  • [Journal-full-title] American journal of epidemiology
  • [ISO-abbreviation] Am. J. Epidemiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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69. Sakamoto K, Ono T, Nakamura Y, Harada H, Nakashima T: Expression of cluster of differentiation 9 glycoprotein in benign and malignant parotid gland tumours. J Laryngol Otol Suppl; 2009;(31):58-63
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of cluster of differentiation 9 glycoprotein in benign and malignant parotid gland tumours.
  • OBJECTIVES: This study aimed to clarify the significance of cluster of differentiation 9 glycoprotein gene expression in human parotid gland tumours.
  • METHODS: We retrospectively analysed immunohistochemical staining for cluster of differentiation 9 glycoprotein in parotid gland tumours.
  • RESULTS: Cluster of differentiation 9 glycoprotein was consistently detected in the normal parotid gland.
  • Regarding benign parotid gland tumours, cluster of differentiation 9 glycoprotein was present in 13 of 18 pleomorphic adenomas, in all Warthin tumours tested (21/21) and in all cases of basal cell adenoma tested (four of four).
  • CONCLUSIONS: There was a statistically significantly reduced expression of cluster of differentiation 9 glycoprotein in malignant parotid gland tumours, compared with benign parotid gland tumours (p < 0.05).
  • These results suggest that a low level of cluster of differentiation 9 glycoprotein expression in parotid gland tumours may be associated with malignancy.
  • [MeSH-major] Antigens, CD / analysis. Membrane Glycoproteins / analysis. Neoplasm Proteins / analysis. Parotid Gland / chemistry. Parotid Neoplasms / chemistry

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  • (PMID = 19460206.001).
  • [ISSN] 0144-2945
  • [Journal-full-title] The Journal of laryngology and otology. Supplement
  • [ISO-abbreviation] J Laryngol Otol Suppl
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD9; 0 / CD9 protein, human; 0 / Membrane Glycoproteins; 0 / Neoplasm Proteins
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70. Wang YY, Chen WL, Yang ZH, Huang ZQ, Li JS, Pan CB: [Effects of Ezrin gene on the proliferation and invasion activity of human salivary gland adenoid cystic carcinoma]. Zhonghua Kou Qiang Yi Xue Za Zhi; 2009 Apr;44(4):203-7
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  • [Title] [Effects of Ezrin gene on the proliferation and invasion activity of human salivary gland adenoid cystic carcinoma].
  • OBJECTIVE: To examine the expression of Ezrin in human salivary gland adenoid cystic carcinoma and investigate the effects of Ezrin gene silence on cell proliferation, apoptosis and invasion of adenoid cystic carcinoma (ACC)-M.
  • METHODS: The expression of Ezrin was detected by immunohistochemistry in normal salivary gland tissue (n=15), pleomorphic adenoma (n=40) and salivary gland adenoid cystic carcinoma (n=43).
  • RESULTS: The positive rate of Ezrin expression in ACC was significantly higher than that in normal salivary gland tissue and pleomorphic adenoma (P<0.05).
  • CONCLUSIONS: Over expression of Ezrin in human salivary gland adenoid cystic carcinoma may promote genesis, development and metastasis of tumors.
  • [MeSH-major] Carcinoma, Adenoid Cystic / genetics. Carcinoma, Adenoid Cystic / pathology. Cytoskeletal Proteins / genetics. Salivary Gland Neoplasms / genetics. Salivary Gland Neoplasms / pathology
  • [MeSH-minor] Apoptosis. Cell Line, Tumor. Cell Proliferation. Gene Expression. Humans. Neoplasm Invasiveness. Neoplasm Metastasis

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  • (PMID = 19575999.001).
  • [ISSN] 1002-0098
  • [Journal-full-title] Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
  • [ISO-abbreviation] Zhonghua Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Cytoskeletal Proteins; 0 / ezrin
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76. Heeremans EH, Mastboom WJ: [Subtotal parotidectomy for a parotid gland tumour in two players of wind instruments, with preservation of facial nerve function]. Ned Tijdschr Geneeskd; 2007 Mar 3;151(9):543-7
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  • [Title] [Subtotal parotidectomy for a parotid gland tumour in two players of wind instruments, with preservation of facial nerve function].
  • [Transliterated title] Subtotale parotidectomie wegens een parotistumor bij twee blaasmuzikanten, met behoud van de N.-facialisfuncties.
  • Two professional musicians, a 55-year-old clarinet player and a 58-year-old trumpet player, presented to the surgical outpatient clinic with a Warthin's tumour and a pleomorphic adenoma in the deep lobe of the parotid gland, respectively.
  • The several branches of the facial nerve form the virtual plane between the superficial and deep lobes of the parotid gland.
  • [MeSH-major] Adenolymphoma / surgery. Adenoma, Pleomorphic / surgery. Facial Nerve / physiology. Parotid Neoplasms / surgery

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  • (PMID = 17373397.001).
  • [ISSN] 0028-2162
  • [Journal-full-title] Nederlands tijdschrift voor geneeskunde
  • [ISO-abbreviation] Ned Tijdschr Geneeskd
  • [Language] dut
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Netherlands
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77. Kornevs E, Tars J, Bigestans A, Lauskis G: Treatment of parotid gland tumors in Latvian Oncological Center. Stomatologija; 2005;7(4):110-4
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  • [Title] Treatment of parotid gland tumors in Latvian Oncological Center.
  • A total of 268 patients were treated for parotid gland lesions at department of Head and Neck Surgery of Latvian Oncological Center between 1996 and 2000, and the results were analyzed retrospectively.
  • The objective was to analyze the incidence and factors associated with facial nerve dysfunction after different types of parotidectomies with facial nerve dissection and to compare the changing attitudes towards the pathology and surgical treatment in order to better define prevention and management of pleomorphic adenoma recurrences.
  • Recurences after the surgical treatment of benign diseases were observed in 12 patients (5.2%).

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  • (PMID = 16501312.001).
  • [ISSN] 1392-8589
  • [Journal-full-title] Stomatologija
  • [ISO-abbreviation] Stomatologija
  • [Language] ENG
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Lithuania
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78. Mortensen KS, Hjortlund J, Bjørndal K, Krogdal A, Godballe C: [Salivary gland tumors in the County of Funen, 1984-2003]. Ugeskr Laeger; 2008 Feb 11;170(7):545-8
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  • [Title] [Salivary gland tumors in the County of Funen, 1984-2003].
  • INTRODUCTION: The objective of this study is to estimate the incidence of major salivary gland tumors in a geographically well-defined area (the County of Funen, Denmark) and to analyse the demographic data and distribution of histological types.
  • MATERIALS AND METHODS: Patients with salivary gland tumors were identified through a search on pathology and diagnosis codes in the period 1984-2003, which initially resulted in a group of 951 patients.
  • RESULTS: The incidence of major salivary gland tumors for the County of Funen is calculated to 7.3 per 100,000 residents per year.
  • Pleomorphic adenoma (55%) was the most common type, followed by adenolymphoma (29%).
  • 90% of the tumors were found in the parotid gland - 93% benign and 7% malignant.
  • 10% were located in the submandibular gland - 73% benign and 27% malignant.
  • Only one neoplasm was located in the sublingual gland and it was malignant (100%).
  • The occurrence of pleomorphic adenomas among females (66%) was higher than among males (43%), on the other hand more adenolymphomas were found in males (43%) than in females (17%).
  • CONCLUSION: The incidence of major salivary gland tumors in the County of Funen is calculated to 7.3 per 100,000 inhabitants per year which is equivalent to 383 new cases in Denmark per year.
  • [MeSH-major] Adenolymphoma / epidemiology. Adenoma, Pleomorphic / epidemiology. Salivary Gland Neoplasms / epidemiology

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  • (PMID = 18291086.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Denmark
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79. Ilhan HD, Oner FH, Sarioglu S, Lebe B, Saatci AO: Bilateral choroidal metastasis from carcinoma ex pleomorphic adenoma of the parotid gland. Clin Exp Ophthalmol; 2005 Feb;33(1):70-2
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  • [Title] Bilateral choroidal metastasis from carcinoma ex pleomorphic adenoma of the parotid gland.
  • The histological, clinical and angiographic findings are reported of a 34-year-old man with bilateral visual loss who had left parotidectomy with subsequent radiotherapy due to carcinoma ex pleomorphic adenoma of the parotid gland 1 year before.
  • Because of the extent of disease and its poor prognosis, no treatment was offered.
  • Although parotid gland carcinoma usually spreads via lymphatics, choroidal involvement may rarely occur due to haematogenous dissemination.
  • [MeSH-major] Adenocarcinoma / secondary. Adenoma, Pleomorphic / pathology. Choroid Neoplasms / secondary. Parotid Neoplasms / pathology

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  • (PMID = 15670083.001).
  • [ISSN] 1442-6404
  • [Journal-full-title] Clinical & experimental ophthalmology
  • [ISO-abbreviation] Clin. Experiment. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Coloring Agents; IX6J1063HV / Indocyanine Green
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80. Porter N, Sandhu A, O'Connell TB, Selva D, Leibovitch I: Pleomorphic adenoma of the palpebral lobe of the lacrimal gland. Otolaryngol Head Neck Surg; 2007 Feb;136(2):328-9
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  • [Title] Pleomorphic adenoma of the palpebral lobe of the lacrimal gland.
  • [MeSH-major] Adenoma, Pleomorphic / surgery. Eye Neoplasms / surgery. Lacrimal Apparatus

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  • (PMID = 17275570.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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81. Franko A, Magliocco AM, Duan Q, Duggan MA: WT1 immunoprofiling and comparison of malignant Mullerian mixed tumors of the female genital tract. Int J Gynecol Pathol; 2010 Sep;29(5):452-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] WT1 immunoprofiling and comparison of malignant Mullerian mixed tumors of the female genital tract.
  • A malignant Mullerian mixed tumor (MMMT) is a biphasic homologous or heterologous malignancy of the female genital tract.
  • WT1 (Wilms tumor 1) is both a tumor suppressor gene and oncogene overexpressed in the nuclei of some gynecologic carcinomas.
  • There were 7 heterologous and 9 homologous tumors and 10 were endometrial, 5 were ovarian, and 1 was of peritoneal origin.
  • The tissue and cell staining pattern and score (intensity by amount) were evaluated and correlated with the tumor subtype and anatomic location.
  • Among the 16 tumors, 81.3% showed mostly stromal and cytoplasmic staining and a score of 3 or 6.
  • Staining was positive in 80% of the endometrial and ovarian tumors and the 1 peritoneal tumor and in all heterologous and 66.7% of the homologous tumors.
  • The immunoprofile correlated with tumor subtype but not with anatomic location.
  • Stromal and epithelial staining was more frequent (83.3%) in homologous tumors and differed significantly (P=0.009) from the heterologous types where stromal staining prevailed (85.7%).
  • MMMT is another genital tract malignancy which can over express WT1 and the immunoprofile may assist in tumor subtyping.
  • [MeSH-major] Genital Neoplasms, Female / metabolism. Genital Neoplasms, Female / pathology. Mixed Tumor, Mullerian / metabolism. Mixed Tumor, Mullerian / pathology. WT1 Proteins / biosynthesis

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  • (PMID = 20736771.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / WT1 Proteins
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82. Dharan M: Metastatic minor salivary gland colloid carcinoma in the parotid region after parotidectomy for pleomorphic adenoma: a case report. Acta Cytol; 2005 Jan-Feb;49(1):101-4
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  • [Title] Metastatic minor salivary gland colloid carcinoma in the parotid region after parotidectomy for pleomorphic adenoma: a case report.
  • BACKGROUND: Primary colloid or mucinous carcinoma of the salivary glands is extremely rare.
  • Only a few cases have been reported that originated in the minor salivary glands. an even more exceptional presentation is as a metastatic tumor in the parotid region subsequent to superficial parotidectomy for pleomorphic adenoma.
  • The case presented here posed a diagnostic dilemma that could be resolved only after a thorough reevaluation of the previous cytologic and histologic material and detection of the occult primary tumor in the hypopharynx following an extensive clinical and radiologic workup.
  • CASE: A 75-year-old female underwent fine needle aspiration of the left parotid and was diagnosed as having pleomorphic adenoma.
  • A superficial parotidectomy removed the tumor completely, and the diagnosis was confirmed.
  • The clinical and radiologic workup in search of a primary lesion led to an occult tumor in the left hypopharyngeal mucosa.
  • CONCLUSION: Unusual presentations of rare tumors can cause considerable diagnostic difficulties to both the clinician and cytopathologist.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Carcinoma, Mucoepidermoid / diagnosis. Carcinoma, Mucoepidermoid / secondary. Parotid Neoplasms / surgery. Salivary Gland Neoplasms / diagnosis. Salivary Gland Neoplasms / secondary


83. Pirola E, Vergani F, Casiraghi P, Leone EB, Guerra P, Sganzerla EP: Oncogenic osteomalacia caused by a phosphaturic mesenchymal tumor of the thoracic spine. J Neurosurg Spine; 2009 Apr;10(4):329-33
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  • [Title] Oncogenic osteomalacia caused by a phosphaturic mesenchymal tumor of the thoracic spine.
  • Phosphaturic mesenchymal tumors that cause the paraneoplastic syndrome known as oncogenic osteomalacia are rare.
  • The authors report on the case of a 57-year-old man with a history of osteomalacia and in whom was diagnosed a thoracic spine tumor at the T-4 level.
  • Complete tumor resection was accomplished.
  • The histological diagnosis was phosphaturic mesenchymal tumor (mixed connective tissue variant).
  • At the 24-month follow-up, no recurrence of the disease was observed.

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  • (PMID = 19441990.001).
  • [ISSN] 1547-5654
  • [Journal-full-title] Journal of neurosurgery. Spine
  • [ISO-abbreviation] J Neurosurg Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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84. Wang EL, Qian ZR, Yamada S, Rahman MM, Inosita N, Kageji T, Endo H, Kudo E, Sano T: Clinicopathological characterization of TSH-producing adenomas: special reference to TSH-immunoreactive but clinically non-functioning adenomas. Endocr Pathol; 2009;20(4):209-20
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  • [Title] Clinicopathological characterization of TSH-producing adenomas: special reference to TSH-immunoreactive but clinically non-functioning adenomas.
  • Thyrotropin (thyroid-stimulating hormone (TSH))-producing pituitary adenomas have been known to be quite variable in clinical features covering from typical functioning TSH-producing adenomas (FTSHomas) associated with hyperthyroidism to clinically silent TSH cell adenomas (STAs) that are apparently unassociated with hyperthyroidism.
  • It is important to distinguish STAs from other types of clinically non-functioning adenomas for adequate postoperative managements.
  • However, because of rareness of TSH-producing adenomas, their histopathological features linking to the clinical manifestations have not been well characterized.
  • Herein, we investigated clinical and histopathological findings to characterize 29 TSH-producing adenomas including 20 FTSHomas and nine STAs.
  • The average tumor size of STAs was significantly larger than that of FTSHomas (P < 0.05).
  • Chromophobic polygonal or short-spindled tumor cells usually proliferated in a diffuse pattern, while they exhibited globoid or whorl-like appearance with intertwined cytoplasmic processes in both subgroups.
  • Their nuclei were somehow pleomorphic.
  • Six tumors showed only a few TSH-positive cells (1-5%), and three were negative for TSH by conventional method without antigen retrieval.
  • After proteinase K treatment, these tumors turned out TSH positive.
  • As defined, STAs were TSH positive in more than 20% of tumor cells and three of them in more than 50%.
  • MIB-1 labeling index was related to tumor invasiveness and tumor size (P < 0.05, P = 0.09, respectively).
  • Thus, although both STAs and FTSHomas showed unique histopathological features distinct from other type adenomas, these two subgroups were indistinguishable by histopathology.
  • Immunohistochemistry for TSH by use of antigen retrieval, transcription factors, and SSTRs may be useful to confirm STAs and to determine the postoperative therapy among various kinds of clinically non-functioning adenomas.
  • [MeSH-major] Adenoma / pathology. Pituitary Neoplasms / pathology. Thyrotropin / analysis. Thyrotropin / biosynthesis

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  • [Cites] Endocr J. 2005 Oct;52(5):605-11 [16284440.001]
  • [Cites] Endocr J. 2007 Jun;54(3):371-8 [17420609.001]
  • [Cites] Cancer Res. 1988 Dec 15;48(24 Pt 1):6977-85 [2903792.001]
  • [Cites] Eur J Endocrinol. 2007 Dec;157(6):717-24 [18057378.001]
  • [Cites] J Neurosurg. 2000 Aug;93(2):194-200 [10930003.001]
  • [Cites] N Engl J Med. 1996 Jan 25;334(4):246-54 [8532003.001]
  • [Cites] Am J Pathol. 1989 Feb;134(2):345-53 [2464941.001]
  • [Cites] Mod Pathol. 1988 May;1(3):212-5 [3237702.001]
  • [Cites] Mod Pathol. 2002 Jan;15(1):11-7 [11796836.001]
  • [Cites] Acta Morphol Hung. 1991;39(1):53-8 [1684693.001]
  • [Cites] J Clin Endocrinol Metab. 1999 Aug;84(8):2942-50 [10443702.001]
  • [Cites] J Biol Chem. 1997 Sep 26;272(39):24339-47 [9305891.001]
  • [Cites] Pituitary. 1999 May;1(3-4):233-41 [11081203.001]
  • [Cites] Eur J Endocrinol. 2007 Jan;156(1):65-74 [17218727.001]
  • [Cites] Am J Pathol. 1980 Mar;98(3):617-38 [6244736.001]
  • [Cites] J Neurooncol. 2008 Nov;90(2):151-6 [18604474.001]
  • [Cites] Ultrastruct Pathol. 2005 Nov-Dec;29(6):511-24 [16316952.001]
  • [Cites] Endocr Rev. 1996 Dec;17(6):610-38 [8969971.001]
  • [Cites] Am J Med. 1960 Mar;28:497-500 [14406535.001]
  • [Cites] Neurol India. 2000 Dec;48(4):374-7 [11146605.001]
  • [Cites] Int J Cancer. 2008 Nov 15;123(10):2229-38 [18777559.001]
  • [Cites] Ann Oncol. 1999;10 Suppl 2:S17-21 [10399028.001]
  • [Cites] J Clin Pathol. 2006 Mar;59(3):274-9 [16505278.001]
  • [Cites] J Clin Endocrinol Metab. 1993 Nov;77(5):1275-80 [8077321.001]
  • [Cites] Mol Cell Biol. 1994 Aug;14(8):5592-602 [7518566.001]
  • [Cites] Endocr J. 2007 Feb;54(1):133-8 [17159301.001]
  • [Cites] Acta Endocrinol (Copenh). 1988 Aug;118(4):533-7 [2840793.001]
  • [Cites] Mod Pathol. 2002 Dec;15(12):1357-65 [12481018.001]
  • [Cites] J Clin Neurosci. 2005 Apr;12(3):318-20 [15851094.001]
  • [Cites] Pituitary. 2009;12(1):80-6 [18350381.001]
  • (PMID = 19774499.001).
  • [ISSN] 1559-0097
  • [Journal-full-title] Endocrine pathology
  • [ISO-abbreviation] Endocr. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / GATA2 Transcription Factor; 0 / RNA, Messenger; 0 / Receptors, Somatostatin; 0 / Transcription Factor Pit-1; 0 / somatostatin receptor 2; 0 / somatostatin receptor 5; 9002-71-5 / Thyrotropin
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85. Ahn JY, Chang JH, Kim SH, Lee KS: Pleomorphic adenocarcinoma of the lacrimal gland with multiple intracranial and spinal metastases. World J Surg Oncol; 2007;5:29
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  • [Title] Pleomorphic adenocarcinoma of the lacrimal gland with multiple intracranial and spinal metastases.
  • BACKGROUND: Pleomorphic adenoma of the lacrimal gland is known to undergo malignant transformation when incompletely excised.
  • CASE PRESENTATION: A 50-year-old woman presented with malignant transformation associated with both intracranial invasion and multiple intracranial and spinal disseminations in the third recurrence of pleomorphic adenoma of the lacrimal gland, 6 years after initial treatment.
  • CONCLUSION: It is important to recognize that leptomeningeal intracranial and spinal disseminations of pleomorphic adenocarcinoma can occur, although it is extremely rare.
  • To our knowledge, we report the first case of pleomorphic adenocarcinoma of the lacrimal gland presumably metastasizing to the intracranium and spine.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma, Pleomorphic / pathology. Eye Neoplasms / pathology. Lacrimal Apparatus / pathology. Neoplasms, Multiple Primary / pathology. Neoplasms, Multiple Primary / surgery
  • [MeSH-minor] Biopsy, Needle. Brain Neoplasms / pathology. Brain Neoplasms / therapy. Disease Progression. Fatal Outcome. Female. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Middle Aged. Neoplasm Invasiveness / pathology. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Neoplasm Staging. Radiosurgery / methods. Risk Assessment. Spinal Neoplasms / pathology. Spinal Neoplasms / therapy

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  • [Cites] Br J Radiol. 1981 Dec;54(648):1034-8 [7296228.001]
  • [Cites] Am J Surg. 1984 Oct;148(4):539-41 [6486324.001]
  • [Cites] Radiother Oncol. 1987 Jul;9(3):175-83 [2819957.001]
  • [Cites] Int Ophthalmol Clin. 1982 Spring;22(1):99-120 [6277818.001]
  • [Cites] Ophthalmology. 1989 Apr;96(4):431-5 [2726173.001]
  • [Cites] Neurol Med Chir (Tokyo). 1990 Dec;30(13):1038-42 [1714052.001]
  • [Cites] Am J Ophthalmol. 1970 Nov;70(5):767-70 [4097730.001]
  • [Cites] Am J Ophthalmol. 1971 Jan;71(1 Pt 2):178-92 [5542123.001]
  • [Cites] Cancer. 1980 May 15;45(10):2593-2606 [7378993.001]
  • [Cites] Ophthalmology. 1980 Jun;87(6):466-75 [7413135.001]
  • [Cites] Arch Ophthalmol. 1998 May;116(5):613-6 [9596497.001]
  • [Cites] Ann Ophthalmol. 1993 Nov;25(11):422-6 [8109884.001]
  • [Cites] Int Ophthalmol Clin. 1993 Summer;33(3):181-8 [8407184.001]
  • [Cites] Br J Ophthalmol. 1992 Jul;76(7):401-7 [1320924.001]
  • [Cites] Br J Ophthalmol. 1992 Jul;76(7):395-400 [1320923.001]
  • (PMID = 17341319.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1820784
  • [General-notes] NLM/ Original DateCompleted: 20070810
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86. de Ru JA, Plantinga RF, Majoor MH, van Benthem PP, Slootweg PJ, Peeters PH, Hordijk GJ: Warthin's tumour and smoking. B-ENT; 2005;1(2):63-6
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  • [Title] Warthin's tumour and smoking.
  • OBJECTIVE: In an evaluation of our patients with parotid gland neoplasms, we noticed that patients with a Warthin's tumour were heavy smokers.
  • The aim of this study was to confirm earlier findings in the literature concerning a possible association between smoking and the development of a Warthin's tumour.
  • METHODS: A case control study was performed using the clinical records and discharge letters of all consecutive patients with a Warthin's tumour in the pathology database of our hospital covering the last 15 years.
  • Patients with a pleomorphic adenoma and a group of patients visiting our audiology department were used as controls.
  • RESULTS: A smoking history was found in 97.5% of the patients with a Warthin's tumour.
  • Of the patients with a pleomorphic adenoma, 59% had a smoking history; 56.5% of the audiology group had a smoking history.
  • Mean age at the time of the operation was 60.1 years of age in the Warthin's tumour group and 48.6 for the pleomorphic adenoma group.
  • CONCLUSION: The mean age for the development of a Warthin's tumour is ten years older than for a pleomorphic adenoma.
  • [MeSH-minor] Adenoma, Pleomorphic / etiology. Adult. Aged. Case-Control Studies. Female. Humans. Male. Middle Aged. Sex Factors. Time Factors

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  • (PMID = 16044736.001).
  • [ISSN] 1781-782X
  • [Journal-full-title] B-ENT
  • [ISO-abbreviation] B-ENT
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Belgium
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87. Sartorius C, Gille F, Bédrossian-Pfingsten J, Kempf HG: [Salivary duct carcinoma of the sublingual gland--a case report]. Laryngorhinootologie; 2006 Jul;85(7):517-9
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  • [Title] [Salivary duct carcinoma of the sublingual gland--a case report].
  • RATIONALE: Pleomorphic adenoma is the most common neoplasm of major and minor salivary gland origin, followed by infectious reasons and sialolithiasis.
  • The salivary duct carcinoma represents a rare variant of the group of adenocarcinomas originated from the salivary glands, especially extremely rare from minor salivary gland origin.
  • CASE REPORT: We report about a 52 year old male patient presenting with painless, non-ulcerating tumor at the floor of the mouth.
  • A biopsy showed a rare salivary duct carcinoma of comedo-type originated from the left sublingual salivary gland.
  • The patient underwent an operation: the tumor was extirpated in toto, and, as the pathohistological investigation confirmed, in sano.
  • Additionally a neck dissection at the left side was performed, followed by the radiation of the tumor region and the lymphatic neck regions, after sufficient reconvalescence.
  • The tumor-classification was pT3, pN0.
  • Since 3 years no recurrence of the tumor was confirmed.
  • DISCUSSION: Salivary duct carcinoma is a rare, high-grade malignant epithelial neoplasm, which occurs almost exclusively in the parotid.
  • As presented, it can also occur in minor salivary glands.
  • Histologically it is composed of structures that resemble expanded salivary glands.
  • Differential diagnosis comprises adenoid cystic carcinoma, metastases of other adenocarcinomas, such as the carcinoma of the thyroid gland and the comedocarcinoma of the breast.
  • CONCLUSION: A rare case of a salivary duct carcinoma of sublingual salivary gland origin is presented.
  • [MeSH-major] Carcinoma, Ductal. Salivary Ducts. Salivary Gland Neoplasms. Sublingual Gland

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  • (PMID = 16586279.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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88. Gopalan R, Dassoulas K, Rainey J, Sherman JH, Sheehan JP: Evaluation of the role of Gamma Knife surgery in the treatment of craniopharyngiomas. Neurosurg Focus; 2008;24(5):E5
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  • The management of craniopharyngioma involves balancing adequate reduction in tumor volume and prevention of recurrence while minimizing damage to delicate surrounding structures.
  • Gamma Knife surgery (GKS) is now being considered as a viable method of providing tumor control while ensuring minimal side effects.
  • Tumor control was achieved in 75% of cases overall and varied with tumor subtype (cystic, solid, mixed).
  • Control was seen in 90% of solid, 80% of cystic, and 59% of mixed tumors.

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  • (PMID = 18447744.001).
  • [ISSN] 1092-0684
  • [Journal-full-title] Neurosurgical focus
  • [ISO-abbreviation] Neurosurg Focus
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 38
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89. Ballas KD, Rafailidis SF, Demertzidis C, Alatsakis MB, Pantzaki A, Sakadamis AK: Mixed exocrine-endocrine tumor of the pancreas. JOP; 2005 Sep;6(5):449-54
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  • [Title] Mixed exocrine-endocrine tumor of the pancreas.
  • Tumors with mixed exocrine and endocrine components are unusual.
  • We herein describe a case of a mixed ductal-endocrine tumor.
  • Upper gastrointestinal endoscopy revealed gastric fundus varices and CT scan demonstrated an inhomogeneous tumor located in the tail of the pancreas infiltrating the spleen and the splenic vein.
  • Pathological examination revealed a mixed ductal-endocrine tumor.
  • CONCLUSIONS: Because of the rarity and unpredictable biologic behavior of these tumors, the need for adjuvant therapy has not yet been well-defined.
  • The patient has had a follow-up CT scan every six months, and one and a half years later remains disease free.
  • [MeSH-major] Carcinoma, Islet Cell / pathology. Carcinoma, Pancreatic Ductal / pathology. Mixed Tumor, Malignant / pathology. Pancreatic Neoplasms / pathology

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  • (PMID = 16186667.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Chromogranins; 0 / Gastrins; 51110-01-1 / Somatostatin; 9007-92-5 / Glucagon; EC 4.2.1.11 / Phosphopyruvate Hydratase
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90. Yang S, Wang HP, Wang XY, Guo LJ, Tang XF, Gao QH, Xuan M, Loo WT, Chow LW: Expression of CD44V6 in parotid pleomorphic adenoma and carcinoma ex pleomorphic adenoma. Expert Opin Investig Drugs; 2010 Apr;19 Suppl 1:S101-8
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  • [Title] Expression of CD44V6 in parotid pleomorphic adenoma and carcinoma ex pleomorphic adenoma.
  • This pattern of expression might be associated with carcinogenesis of parotid pleomorphic adenoma (PPA) which is not widely studied.
  • METHODS: Expression differences of CD44v6 were detected by immunohistochemistry in samples of non-recurrent PPA, PPA before and after the recurrence, carcinoma in pleomorphic adenoma (CPA) and normal parotid.
  • [MeSH-major] Adenoma, Pleomorphic / genetics. Antigens, CD44 / genetics. Gene Expression Regulation, Neoplastic / genetics. Parotid Neoplasms / genetics

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  • (PMID = 20374021.001).
  • [ISSN] 1744-7658
  • [Journal-full-title] Expert opinion on investigational drugs
  • [ISO-abbreviation] Expert Opin Investig Drugs
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD44; 0 / CD44v6 antigen
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91. Mallina S, Rosalind S, Philip R, Harvinder S, Gurdeep S, Sabaria MN: Nodular fasciitis: a diagnostic dilemma. Med J Malaysia; 2007 Dec;62(5):420-1
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  • A diagnosis of pleomorphic adenoma was reported on fine needle aspiration cytology (FNAC).
  • The tumor was excised and a diagnosis of nodular fasciitis was made.
  • It is important to be aware of this diagnosis and that FNAC reports may mimic that of a pleomorphic adenoma.
  • [MeSH-minor] Adenoma, Pleomorphic / diagnosis. Aged. Diagnosis, Differential. Head and Neck Neoplasms / diagnosis. Humans. Male

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  • (PMID = 18705482.001).
  • [ISSN] 0300-5283
  • [Journal-full-title] The Medical journal of Malaysia
  • [ISO-abbreviation] Med. J. Malaysia
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Malaysia
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92. Fowler MH, Fowler J, Ducatman B, Barnes L, Hunt JL: Malignant mixed tumors of the salivary gland: a study of loss of heterozygosity in tumor suppressor genes. Mod Pathol; 2006 Mar;19(3):350-5
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  • [Title] Malignant mixed tumors of the salivary gland: a study of loss of heterozygosity in tumor suppressor genes.
  • Carcinosarcomas and carcinoma ex pleomorphic adenoma of the salivary glands are rare tumors that fit into the broader category of malignant mixed tumors.
  • Although most evidence has suggested that the different morphologic components arise from a common clonal origin, there are very few studies that have provided molecular evidence for this clonality.
  • In this study, we examined a set of seven carcinosarcomas and four carcinomas ex pleomorphic adenoma for tumor suppressor gene loss of heterozygosity, in order to assess the clonal patterns in the varying components.
  • Microdissection was performed to obtain each morphological component and tumor suppressor gene loci on 3p, 5q, 9p, 17p, 17q, and 18q were analyzed.
  • In carcinosarcomas, the sarcomatous targets had a higher mean FAL than the carcinomatous targets (68 vs 46%, respectively) and in carcinomas ex pleomorphic adenoma, the mean FAL in the benign component was 11 vs 46% seen in the carcinomatous component.
  • Loss of heterozygosity of 17q21 and 9p21 only occurred in carcinosarcomas and not in carcinomas ex pleomorphic adenoma.
  • In carcinomas ex pleomorphic adenoma, loss of heterozygosity was uncommon in the benign component, but the mutations were conserved in the corresponding malignant areas.
  • Furthermore, these data support prior studies that suggest a common clonal origin for the benign and malignant components of carcinomas ex pleomorphic adenoma.
  • [MeSH-major] Genes, Tumor Suppressor. Loss of Heterozygosity / genetics. Mixed Tumor, Malignant / pathology. Salivary Gland Neoplasms / pathology

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  • (PMID = 16400327.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / NM23 Nucleoside Diphosphate Kinases; EC 2.7.4.6 / NME1 protein, human; EC 2.7.4.6 / Nucleoside-Diphosphate Kinase
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93. Seijas R, Ares O, Sierra J, Pérez-Dominguez M: Oncogenic osteomalacia: two case reports with surprisingly different outcomes. Arch Orthop Trauma Surg; 2009 Apr;129(4):533-9
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  • This condition is usually associated with a phosphaturic mesenchymal tumor of mixed connective tissue located in the bone or soft tissue.
  • We present two cases of oncogenic osteomalacia associated with phosphaturic mesenchymal tumors, which were histologically similar, but presented a completely different evolution.
  • In the first patient, the tumor developed on the sole of the foot.
  • However, in the second patient, a liver tumor developed and resection did not resolve the disease.
  • This disease usually remits with complete tumor resection.
  • If scintigraphy of the tumor shows octreotide receptors, patients may respond partially to therapy with somatostatin analogs, with stabilization of the lesion.

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  • (PMID = 19125258.001).
  • [ISSN] 1434-3916
  • [Journal-full-title] Archives of orthopaedic and trauma surgery
  • [ISO-abbreviation] Arch Orthop Trauma Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Indium Radioisotopes; 0 / Receptors, Somatostatin; 51110-01-1 / Somatostatin; G083B71P98 / pentetreotide; RWM8CCW8GP / Octreotide
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94. Tsutsumi S, Kondo A, Yasumoto Y, Ito M: Rapid growth of congenital diffuse brain tumor considered to be teratoma: case report. Neurol Med Chir (Tokyo); 2008 Jul;48(7):322-5
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  • [Title] Rapid growth of congenital diffuse brain tumor considered to be teratoma: case report.
  • Prenatal ultrasonography of a 17-year-old pregnant female detected ventriculomegaly of the fetus at 31 weeks of gestation.
  • Computed tomography performed on postnatal day 5 revealed a massive brain tumor of mixed density, with multiple lobulation and cystic and calcified components.
  • The tumor had rapidly grown with diffuse appearance.
  • The tumor appeared hypervascular and bled profusely on resection maneuver, so the endoscopic procedure for histological verification was abandoned.
  • Neuroimaging performed on postnatal day 11 indicated significant additional tumor growth which occupied nearly the whole cranial cavity.
  • [MeSH-minor] Adolescent. Biopsy. Endoscopy. Fatal Outcome. Female. Humans. Hydrocephalus / pathology. Infant, Newborn. Male. Pregnancy. Tumor Burden. Ventriculostomy

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  • (PMID = 18654054.001).
  • [ISSN] 1349-8029
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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95. Benazzou S, Boulaadas M, Sefiani S, El Kohen A, Essakalli L, Kzadri M: Mucoepidermoid carcinoma arising from pleomorphic adenoma of the soft palate. J Craniofac Surg; 2006 Nov;17(6):1192-4
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  • [Title] Mucoepidermoid carcinoma arising from pleomorphic adenoma of the soft palate.
  • Carcinoma arising in pleomorphic adenoma is a rare entity.
  • A case of mucoepidermoid carcinoma in pleomorphic adenoma occurring in the soft palate of a 40-year-old woman is reported.
  • An intraoral excision of the tumor was performed.
  • Histopathological examination revealed high-grade mucoepidermoid carcinoma proliferated in pleomorphic adenoma with free surgical margin.
  • She remains free of disease 16 months post-treatment.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Carcinoma, Mucoepidermoid / pathology. Neoplasms, Multiple Primary / pathology. Palatal Neoplasms / pathology. Palate, Soft / pathology. Salivary Gland Neoplasms / pathology

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  • (PMID = 17119430.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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96. Fiorella R, Di Nicola V, Fiorella ML, Spinelli DA, Coppola F, Luperto P, Madami L: Major salivary gland diseases. Multicentre study. Acta Otorhinolaryngol Ital; 2005 Jun;25(3):182-90
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  • [Title] Major salivary gland diseases. Multicentre study.
  • This multicentre study involved 28 Italian ORL Centres responding to a questionnaire sent by us which allowed recruitment of a high large number of cases of parotid neoplasms observed over a 10-year period.
  • Benign tumours account for 80% of case histories with a relationship 1:4 M/F, the most frequent being pleomorphic adenoma (57.3% of cases), followed by Warthin's tumour (32.4%), this rating not having been confirmed in case histories (8-10%) in the literature.
  • Surgical treatment of benign tumours consisted, in 50% of cases, in superficial paroditectomy and in approximately 30% of total paroditectomy.
  • Enucleoresection was limited to approximately 15% of neoplasms, enucleation to <10% of cases with only 2% of pleomorph adenoma due to the well-known anatomo-pathological characteristics which may lead to relapse.
  • The lateral neck dissection most frequently carried out was of functional type in 54% and selective type in 46% with removal of levels I-III and II-IV in approximately 60% of cases.
  • When no clinically evident lymph nodes were present (NO) considering the tumour histotype, two thirds of patients underwent surgery or radiotherapy, while in the remainder the wait-and-see attitude was prefered.
  • Oncological results obtained were compared with those reported in the literature: in fact for all benign neoplasms relapse ratings are about 5%, while for malignant tumours the worst prognosis was in squamous cell carcinoma with median of 37.7 on survival and metastasis rate of 16.5%.
  • [MeSH-major] Salivary Gland Neoplasms

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  • [Cites] Australas Radiol. 1999 Nov;43(4):520-2 [10901971.001]
  • [Cites] Laryngoscope. 2001 Nov;111(11 Pt 1):1984-8 [11801983.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2002 Mar 1;52(3):729-38 [11849796.001]
  • [Cites] Atlas Oral Maxillofac Surg Clin North Am. 1998 Mar;6(1):1-28 [11905347.001]
  • [Cites] J Laryngol Otol. 2002 Apr;116(4):285-7 [11945190.001]
  • [Cites] Acta Otorhinolaryngol Ital. 2002 Apr;22(2):80-5 [12068476.001]
  • [Cites] J Laryngol Otol. 2002 May;116(5):359-62 [12080993.001]
  • [Cites] Laryngoscope. 2002 Dec;112(12):2141-54 [12461331.001]
  • [Cites] Mund Kiefer Gesichtschir. 2003 Mar;7(2):94-101 [12664254.001]
  • [Cites] Anticancer Res. 2003 Mar-Apr;23(2A):931-40 [12820326.001]
  • [Cites] Am J Surg. 2003 Jul;186(1):57-62 [12842751.001]
  • [Cites] Laryngoscope. 2003 Aug;113(8):1299-303 [12897549.001]
  • [Cites] Tumori. 2003 Jul-Aug;89(4 Suppl):257-9 [12903612.001]
  • [Cites] J Laryngol Otol. 2003 Aug;117(8):624-9 [12956917.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 2003 Sep;129(9):929-33 [12975263.001]
  • [Cites] World J Surg. 2003 Jul;27(7):863-7 [14509520.001]
  • [Cites] Head Neck. 2003 Nov;25(11):946-52 [14603455.001]
  • [Cites] Chir Ital. 2003 Nov-Dec;55(6):857-64 [14725226.001]
  • [Cites] Eur Arch Otorhinolaryngol. 2004 Mar;261(3):143-6 [12883818.001]
  • [Cites] Otolaryngol Pol. 2004;58(1):109-14 [15101269.001]
  • [Cites] Surg Oncol Clin N Am. 2004 Jan;13(1):113-27 [15062365.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 2004 Jun;130(6):773-8 [15210562.001]
  • [Cites] J Pathol. 1985 May;146(1):51-8 [4009321.001]
  • [Cites] Head Neck Surg. 1986 Jan-Feb;8(3):177-84 [3744850.001]
  • [Cites] Hua Xi Kou Qiang Yi Xue Za Zhi. 2005 Feb;23(1):53-6 [15804023.001]
  • [ErratumIn] Acta Otorhinolaryngol Ital. 2005 Oct;25(5):following 337
  • (PMID = 16450775.001).
  • [ISSN] 0392-100X
  • [Journal-full-title] Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale
  • [ISO-abbreviation] Acta Otorhinolaryngol Ital
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2639866
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97. Rødahl E, Lybaek H, Arnes J, Ness GO: Chromosomal imbalances in some benign orbital tumours. Acta Ophthalmol Scand; 2005 Jun;83(3):385-91
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  • [Title] Chromosomal imbalances in some benign orbital tumours.
  • PURPOSE: To examine benign orbital tumours for chromosomal imbalances.
  • RESULTS: Chromosomal gains or losses were seen in 4/6 pleomorphic adenomas (gains at 8q; losses at 4p, 5p, 8p, 11p and 14q), 2/4 schwannomas (losses at 16p and 22q), and 1/9 cavernous haemangiomas (losses at 13q).
  • Compared to previous studies of pleomorphic adenomas using G-band analysis, chromosomal imbalances were more frequently detected by using CGH.
  • Gains of 8q11-q22 and losses of 4p15-pter, 11p12-p15, and 14q12-q23 in pleomorphic adenomas, losses of 16p12-p13 in schwannomas, and losses of 13q32-qter in cavernous haemangiomas have not been reported previously.
  • The clinical relevance of the abnormalities is uncertain, but they may indicate the position of genes that could play a role in tumour development.
  • [MeSH-major] Adenoma, Pleomorphic / genetics. Chromosome Aberrations. Hemangioma, Cavernous / genetics. Neurilemmoma / genetics. Orbital Neoplasms / genetics

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  • (PMID = 15948796.001).
  • [ISSN] 1395-3907
  • [Journal-full-title] Acta ophthalmologica Scandinavica
  • [ISO-abbreviation] Acta Ophthalmol Scand
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
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98. Miyata S, Gomi A, Yamaguchi T, Tanaka Y, Watanabe E, Tanaka A: Case of unclassified, radiosensitive, malignant neuroepithelial tumor in the temporal lobe of a child. Brain Tumor Pathol; 2010 Apr;27(1):45-50
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  • [Title] Case of unclassified, radiosensitive, malignant neuroepithelial tumor in the temporal lobe of a child.
  • A case of unclassified, pediatric cerebral neuroepithelial tumor in a 10-year-old girl that showed remarkable radiosensitivity is reported.
  • MRI revealed a brain tumor of mixed intensity with heterogeneous enhancement in the medial temporal lobe, extending to the basal ganglia.
  • The tumor was partially removed.
  • On pathology, the main part of the tumor showed immature features: the tumor cells had a chromatin-rich large nucleus and less cytoplasm, and mitoses and fragmentation of the nuclei were frequent.
  • On immunohistochemistry, the tumor cells were negative for glial fibrillary acidic protein (GFAP) and synaptophysin and positive for Olig2.
  • The infiltrating tumor cells were positive for GFAP and less positive for Olig2.
  • After 40 Gy radiation, the residual tumor was markedly reduced.
  • Neuroepithelial tumors rarely show such high radiosensitivity, and the reason for the radiosensitivity in the present case may have been the immaturity of the tumor cells.
  • [MeSH-minor] Astrocytoma. Basic Helix-Loop-Helix Transcription Factors / analysis. Biomarkers, Tumor / analysis. Child. Combined Modality Therapy. Female. Glial Fibrillary Acidic Protein / analysis. Humans. Ki-67 Antigen / analysis. Neoplasm, Residual. Nerve Tissue Proteins / analysis. Radiotherapy Dosage. Synaptophysin / analysis. Treatment Outcome

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  • (PMID = 20425048.001).
  • [ISSN] 1861-387X
  • [Journal-full-title] Brain tumor pathology
  • [ISO-abbreviation] Brain Tumor Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Basic Helix-Loop-Helix Transcription Factors; 0 / Biomarkers, Tumor; 0 / Glial Fibrillary Acidic Protein; 0 / Ki-67 Antigen; 0 / Nerve Tissue Proteins; 0 / OLIG2 protein, human; 0 / Synaptophysin
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99. Allon I, Vered M, Buchner A, Dayan D: Stromal differences in salivary gland tumors of a common histopathogenesis but with different biological behavior: a study with picrosirius red and polarizing microscopy. Acta Histochem; 2006;108(4):259-64
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  • [Title] Stromal differences in salivary gland tumors of a common histopathogenesis but with different biological behavior: a study with picrosirius red and polarizing microscopy.
  • Salivary gland neoplasms - pleomorphic adenoma, polymorphous low-grade adenocarcinoma, and adenoid cystic carcinoma - share a common histogenetic trait, but differ markedly in their biological properties.
  • The objective of the study was to assess the polarization colors of picrosirius red-stained stromal collagen fibers in these salivary gland neoplasms to evaluate their possible role in the histopathogenesis of the tumors and to evaluate the potential usefulness of this approach as a diagnostic tool.
  • Ten cases of each tumor type and 10 cases of mucous extravasation phenomenon (control) were examined using picrosirius red staining and polarizing microscopy.
  • Results showed a similar thin fiber distribution in all tumor types and controls (82-88% green-yellow, 12-18% yellow-orange, p>0.05).
  • Thick fibers showed a different distribution in polymorphous low-grade adenocarcinoma and adenoid cystic carcinoma (approximately 50% green-yellow) compared to pleomorphic adenoma and mucous extravasation phenomenon (approximately 13% green-yellow) (p=0.001).
  • We conclude that with picrosirius red staining and polarizing microscopy, stromal collagen fibers differ significantly in pleomorphic adenoma from those in polymorphous low-grade adenocarcinoma and adenoid cystic carcinoma, but not from mucous extravasation phenomenon.
  • Similarity between polymorphous low-grade adenocarcinoma and adenoid cystic carcinoma may indicate that these tumor types represent a single entity with a broad spectrum of biological behavior.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma, Pleomorphic / pathology. Azo Compounds. Carcinoma, Adenoid Cystic / pathology. Salivary Gland Neoplasms / pathology. Stromal Cells / pathology

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  • (PMID = 16899283.001).
  • [ISSN] 0065-1281
  • [Journal-full-title] Acta histochemica
  • [ISO-abbreviation] Acta Histochem.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Azo Compounds; 0 / Coloring Agents; 0 / Fibrillar Collagens; 1294D5G72N / C.I. direct red 80
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100. Mazumder SM, Tarafder KH, Doulatuzzaman, Sikder A, Sayed S, Alauddin M: Parotidectomy--a prospective study. J Indian Med Assoc; 2008 Jan;106(1):16, 18, 20
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  • Fifty-eight patients were suffering from neoplastic conditions of which 46 had pleomorphic adenoma, 7 had muco-epidermoid carcinoma, 3 had carcinoma ex-pleomorphic adenoma, and 2 had adenoid cystic carcinoma.
  • [MeSH-major] Otorhinolaryngologic Surgical Procedures / methods. Parotid Diseases / surgery. Parotid Gland / surgery

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  • (PMID = 18705263.001).
  • [ISSN] 0019-5847
  • [Journal-full-title] Journal of the Indian Medical Association
  • [ISO-abbreviation] J Indian Med Assoc
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study
  • [Publication-country] India
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