[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 100 of about 826
1. Silverberg SJ: Vitamin D deficiency and primary hyperparathyroidism. J Bone Miner Res; 2007 Dec;22 Suppl 2:V100-4
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Vitamin D deficiency and primary hyperparathyroidism.
  • Temporally associated with the improvement in vitamin D nutrition in many Western countries in the mid-20th century, there was a change in many characteristics of primary hyperparathyroidism.
  • At the same time, in patients with the disease, levels of PTH and parathyroid adenoma weights have fallen dramatically.
  • In view of these observations and others, an association between vitamin D deficiency and severity of primary hyperparathyroidism has been proposed.
  • First, regardless of the clinical severity of primary hyperparathyroidism, the disease seems to be more severe in those with concomitant vitamin D deficiency.
  • Second, vitamin D deficiency and insufficiency seem to be more prevalent in patients with primary hyperparathyroidism than in geographically matched populations.
  • The association between vitamin D deficiency and primary hyperparathyroidism has clear implications.
  • With regard to management, preliminary data on vitamin D repletion in patients with mild primary hyperparathyroidism suggest that, in some cases, correction of vitamin D deficiency may be accomplished without worsening the underlying hypercalcemia.
  • Vitamin D-deficient patients undergoing parathyroidectomy are also at increased risk of postoperative hypocalcemia and "hungry bone syndrome," which underscores the importance of preoperative assessment of vitamin D status in all patients with primary hyperparathyroidism.
  • [MeSH-major] Hyperparathyroidism, Primary / complications. Vitamin D Deficiency / complications
  • [MeSH-minor] Humans. Parathyroid Hormone / blood. Vitamin D / analogs & derivatives. Vitamin D / blood

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • MedlinePlus Health Information. consumer health - Vitamin D Deficiency.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18290710.001).
  • [ISSN] 1523-4681
  • [Journal-full-title] Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
  • [ISO-abbreviation] J. Bone Miner. Res.
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / DK074457; United States / NIDDK NIH HHS / DK / DK32333; United States / NIDDK NIH HHS / DK / K24 DK074457
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Parathyroid Hormone; 1406-16-2 / Vitamin D; 64719-49-9 / 25-hydroxyvitamin D
  • [Number-of-references] 37
  •  go-up   go-down


2. Lin SD, Tu ST, Hsu SR, Chang JH, Yang KT, Yang LH: Synchronous parathyroid and papillary thyroid carcinoma. J Chin Med Assoc; 2005 Feb;68(2):87-91
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Synchronous parathyroid and papillary thyroid carcinoma.
  • Concomitant thyroid disease is not unusual among patients with primary hyperparathyroidism.
  • However, the simultaneous occurrence of parathyroid and thyroid carcinoma is extremely rare.
  • We report a 38-year-old man with primary hyperparathyroidism who presented with osteitis fibrosa cystica complicated with pathologic femoral neck fracture.
  • Preoperative investigation for exclusion of multiple endocrine neoplasia did not find evidence of medullary thyroid carcinoma or pheochromocytoma, but imaging studies revealed the presence of nodules in the right lobe and a parathyroid lesion over the left inferior pole of the thyroid gland.
  • The resected specimens were pathologically identified as papillary thyroid carcinoma and parathyroid carcinoma, respectively.
  • Although parathyroid carcinoma is an uncommon cause of parathyroid hormone-dependent hypercalcemia, it should nonetheless be given due consideration because its surgical approach differs from that of parathyroid adenoma.
  • As the coexistence of parathyroid and non-medullary thyroid carcinoma has previously been reported, the possibility of both malignancies must also be considered in the setting of primary hyperparathyroidism with thyroid nodules.
  • If confirmed with preoperative parathyroid scintigraphic and other laboratory studies, an optimal outcome may be achieved with complete resection of both tumors at the time of initial operation, followed by adjunctive therapy.
  • [MeSH-major] Carcinoma, Papillary / complications. Neoplasms, Multiple Primary / complications. Parathyroid Neoplasms / complications. Thyroid Neoplasms / complications
  • [MeSH-minor] Adult. Humans. Hyperparathyroidism / etiology. Male. Parathyroid Glands / pathology. Parathyroid Glands / surgery. Parathyroidectomy. Thyroid Gland / pathology. Thyroid Gland / surgery. Thyroidectomy. Treatment Outcome. Urinary Calculi / etiology

  • Genetic Alliance. consumer health - Parathyroid carcinoma.
  • MedlinePlus Health Information. consumer health - Thyroid Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15759821.001).
  • [ISSN] 1726-4901
  • [Journal-full-title] Journal of the Chinese Medical Association : JCMA
  • [ISO-abbreviation] J Chin Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
  •  go-up   go-down


3. Mehrotra PK, Agarwal A, Kumar N, Mishra A, Agarwal G, Verma AK, Mishra SK: Comments on 'Technetium-99m-sestamibi subtraction scintigraphy vs. ultrasonography combined with a rapid parathyroid hormone assay in parathyroid aspirates in preoperative localization of parathyroid adenomas and in directing surgical approach'. Clin Endocrinol (Oxf); 2007 Jun;66(6):899
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comments on 'Technetium-99m-sestamibi subtraction scintigraphy vs. ultrasonography combined with a rapid parathyroid hormone assay in parathyroid aspirates in preoperative localization of parathyroid adenomas and in directing surgical approach'.
  • [MeSH-major] Parathyroid Neoplasms / diagnosis
  • [MeSH-minor] Humans. Minimally Invasive Surgical Procedures. Parathyroid Hormone / blood. Radiopharmaceuticals. Technetium Tc 99m Sestamibi

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentOn] Clin Endocrinol (Oxf). 2006 Jul;65(1):106-13 [16817828.001]
  • (PMID = 17388797.001).
  • [ISSN] 0300-0664
  • [Journal-full-title] Clinical endocrinology
  • [ISO-abbreviation] Clin. Endocrinol. (Oxf)
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] England
  • [Chemical-registry-number] 0 / PTH protein, human; 0 / Parathyroid Hormone; 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


Advertisement
4. Gannagé-Yared MH, Abboud B, Amm-Azar M, Saab A, Khalife S, Halaby G, Atallah C, Medlej R, Jambart S: Predictors of intra-operative parathyroid hormone decline in subjects operated for primary hyperparathyroidism by minimally invasive parathyroidectomy. J Endocrinol Invest; 2009 Feb;32(2):160-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Predictors of intra-operative parathyroid hormone decline in subjects operated for primary hyperparathyroidism by minimally invasive parathyroidectomy.
  • BACKGROUND: The predictors of intra-operative PTH (IOPTH) decline during minimally invasive parathyroidectomy (MIP) for primary hyperparathyroidism have been but poorly studied.
  • MATERIALS AND METHODS: This retrospective study included 108 patients who underwent MIP for a single adenoma.
  • IOPTH was measured before (intra-operative preincision or PTHt0) and 10 min after removal of the adenoma (PTHt10).
  • The weight of the adenoma was assessed in all the subjects.
  • The PTH dropped from a mean value of 184.8 to 50.8 pg/ml 10 min after adenoma resection with a mean drop of 69.7%.
  • In a bivariate analysis, age, an MDRD<60 ml/min and weight of adenoma were inversely associated with IOPTH fall (p=0.009, p=0.004, and p<0.001, respectively) while gender, body mass index, hypertension, diabetes, pre-operative phosphorus and calcium had no significant effects.
  • In the multivariate analysis, age, weight of adenoma, and MDRD were still independent negative predictors of the IOPTH fall (p=0.01, p=0.018, and p<0.001, respectively).
  • CONCLUSION: Our results suggest that during MIP the presence of a parathyroid adenoma with a high weight, in an elderly subject or in a subject with altered renal function, will result in a lesser degree of IOPTH fall.
  • [MeSH-major] Adenoma / surgery. Monitoring, Intraoperative. Parathyroid Hormone / blood. Parathyroid Neoplasms / surgery. Parathyroidectomy / methods
  • [MeSH-minor] Aged. Calcium / blood. Female. Humans. Hyperparathyroidism, Primary / surgery. Male. Middle Aged. Minimally Invasive Surgical Procedures. Phosphorus / blood. Retrospective Studies

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .
  • Hazardous Substances Data Bank. PHOSPHORUS, ELEMENTAL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Clin Endocrinol Metab. 1999 Nov;84(11):4287-90 [10566687.001]
  • [Cites] World J Surg. 2002 Aug;26(8):926-30 [11965444.001]
  • [Cites] Surgery. 2003 Dec;134(6):910-7; discussion 917 [14668722.001]
  • [Cites] Clin Chem. 2004 Jul;50(7):1126-35 [15117855.001]
  • [Cites] World J Surg. 2006 Mar;30(3):321-6 [16467981.001]
  • [Cites] Surg Clin North Am. 2004 Jun;84(3):717-34 [15145230.001]
  • [Cites] World J Surg. 2006 Feb;30(2):156-61 [16425080.001]
  • [Cites] Ann Surg. 2005 Sep;242(3):375-80; discussion 380-3 [16135923.001]
  • [Cites] J Am Coll Surg. 2002 Feb;194(2):126-30 [11848628.001]
  • [Cites] Am J Surg. 1992 Mar;163(3):301-4 [1539763.001]
  • [Cites] Arch Surg. 2005 May;140(5):472-8; discussion 478-9 [15897443.001]
  • [Cites] World J Surg. 2002 Aug;26(8):1074-7 [12016487.001]
  • [Cites] Arch Pathol Lab Med. 2003 Nov;127(11):1424-42 [14567726.001]
  • [Cites] J Am Coll Surg. 2006 Jul;203(1):1-6 [16798481.001]
  • [Cites] World J Surg. 2005 Jun;29(6):785-8 [15883666.001]
  • [Cites] Arch Surg. 2002 Sep;137(9):1055-9 [12215160.001]
  • [Cites] Clin Otolaryngol. 2007 Jun;32(3):179-84 [17550505.001]
  • [Cites] Laryngoscope. 2007 Nov;117(11):1957-60 [17891053.001]
  • [Cites] J Am Coll Surg. 2004 Aug;199(2):229-33 [15275878.001]
  • [Cites] Surgery. 2005 Oct;138(4):583-7; discussion 587-90 [16269285.001]
  • [Cites] Surgery. 1999 Dec;126(6):1016-21; discussion 1021-2 [10598182.001]
  • [Cites] Surgery. 1993 Dec;114(6):1019-22; discussion 1022-3 [8256205.001]
  • [Cites] Clin Chem. 2001 May;47(5):919-25 [11325897.001]
  • [Cites] Clin Chim Acta. 2007 Apr;379(1-2):14-28; discussion 29-30 [17270169.001]
  • [Cites] Surgery. 2003 Dec;134(6):973-9; discussion 979-81 [14668730.001]
  • [Cites] Ann Surg Oncol. 2008 Feb;15(2):493-8 [18026797.001]
  • [Cites] World J Surg. 1991 Nov-Dec;15(6):688-92 [1767534.001]
  • [Cites] J Am Coll Surg. 1997 Feb;184(2):126-36 [9022630.001]
  • [Cites] Clin Endocrinol (Oxf). 2005 Nov;63(5):506-13 [16268801.001]
  • [Cites] J Clin Endocrinol Metab. 2000 Mar;85(3):1054-8 [10720039.001]
  • [Cites] Surgery. 2007 Dec;142(6):930-5; discussion 930-5 [18063078.001]
  • [Cites] J Am Coll Surg. 2004 Dec;199(6):849-53; discussion 853-5 [15555964.001]
  • [Cites] Eur J Endocrinol. 2006 Aug;155(2):237-44 [16868136.001]
  • [Cites] Surgery. 1999 Dec;126(6):1132-7; discussion 1137-8 [10598198.001]
  • [Cites] Head Neck. 2002 Nov;24(11):1000-3 [12410535.001]
  • [Cites] Clin Endocrinol (Oxf). 2007 Jun;66(6):878-85 [17437518.001]
  • [Cites] Ann Surg. 2002 May;235(5):665-70; discussion 670-2 [11981212.001]
  • [Cites] Clin Chem. 2000 Oct;46(10):1662-8 [11017947.001]
  • [Cites] Am J Surg. 2007 Mar;193(3):368-72; discussion 372-3 [17320537.001]
  • [Cites] ANZ J Surg. 2006 Oct;76(10):882-5 [17007616.001]
  • [Cites] World J Surg. 2004 Dec;28(12):1287-92 [15517474.001]
  • (PMID = 19411816.001).
  • [ISSN] 1720-8386
  • [Journal-full-title] Journal of endocrinological investigation
  • [ISO-abbreviation] J. Endocrinol. Invest.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / PTH protein, human; 0 / Parathyroid Hormone; 27YLU75U4W / Phosphorus; SY7Q814VUP / Calcium
  •  go-up   go-down


5. Yeh MW, Barraclough BM, Sidhu SB, Sywak MS, Barraclough BH, Delbridge LW: Two hundred consecutive parathyroid ultrasound studies by a single clinician: the impact of experience. Endocr Pract; 2006 May-Jun;12(3):257-63
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Two hundred consecutive parathyroid ultrasound studies by a single clinician: the impact of experience.
  • OBJECTIVE: To assess the ability of ultrasound studies, performed by an experienced clinician, to predict surgical findings and provide precise anatomic localization of abnormal parathyroid glands.
  • METHODS: We retrospectively examined 200 consecutive parathyroid ultrasound studies performed by a single experienced clinician in our unit.
  • All patients subsequently underwent parathyroidectomy, with histopathologic confirmation of abnormal parathyroid tissue.
  • Ultrasound studies correctly predicted the surgical findings in 88% of patients, including 168 of 180 (93%) with single gland disease and 7 of 20 (35%) with multiple gland disease (MGD).
  • In all cases in which a single adenoma was identified, precise information regarding its location relative to adjacent anatomic structures was provided.
  • Ectopic and descended superior adenomas were most frequently missed.
  • CONCLUSION: In experienced hands, parathyroid ultrasonography is a highly sensitive technique that provides both localization of enlarged parathyroid glands and precise anatomic detail.
  • Nonlocalizing studies should alert the surgeon to a high probability of MGD and prompt the performance of 4-gland exploration.
  • [MeSH-major] Adenoma / ultrasonography. Clinical Competence. Parathyroid Diseases / ultrasonography. Parathyroid Glands / ultrasonography. Parathyroid Neoplasms / ultrasonography

  • MedlinePlus Health Information. consumer health - Parathyroid Disorders.
  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16772196.001).
  • [ISSN] 1530-891X
  • [Journal-full-title] Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
  • [ISO-abbreviation] Endocr Pract
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] SY7Q814VUP / Calcium
  •  go-up   go-down


6. Kiverniti E, Kazi R, Rhys-Evans P, Nippah R: Airway obstruction due to giant non-parathyroid hormone-producing parathyroid adenoma. J Cancer Res Ther; 2008 Oct-Dec;4(4):197-9
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Airway obstruction due to giant non-parathyroid hormone-producing parathyroid adenoma.
  • Parathyroid gland tumors are unusual in the differential diagnosis of mediastinal tumors.
  • The eventual diagnosis on histology was parathyroid adenoma.
  • The patient had no clinical evidence of metabolic abnormalities and her pre- and postoperative calcium and postoperative parathyroid hormone (PTH) levels were within normal limits.
  • This case poses the interesting question of whether identification of elevated PTH levels is an absolute prerequisite for diagnosing parathyroid adenomas.
  • [MeSH-major] Parathyroid Neoplasms / complications
  • [MeSH-minor] Adenoma. Adult. Airway Obstruction. Esophagus / metabolism. Female. Humans. Mediastinal Neoplasms / metabolism. Medical Oncology / methods. Parathyroid Hormone / metabolism. Tomography, X-Ray Computed / methods. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19052395.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Parathyroid Hormone
  •  go-up   go-down


7. Berri RN, Lloyd LR: Detection of parathyroid adenoma in patients with primary hyperparathyroidism: the use of office-based ultrasound in preoperative localization. Am J Surg; 2006 Mar;191(3):311-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Detection of parathyroid adenoma in patients with primary hyperparathyroidism: the use of office-based ultrasound in preoperative localization.
  • BACKGROUND: The purpose of this investigation is to show that preoperative localization of the parathyroid gland using office-based ultrasound (US) and Tc-99m sestamibi scan is superior to all other approaches in detecting a parathyroid adenoma.
  • METHODS: We performed a retrospective analysis of 43 patients who underwent parathyroidectomy for primary hyperparathyroidism.
  • RESULTS: In 42 of 43 patients, office-based US performed by a surgeon and sestamibi scintigraphy successfully detected the location of a parathyroid abnormality (42/43 cases, sensitivity = 98%, P < .05 =.0001).
  • Office-based US localized the abnormal gland to the specific side (right/left) in 36 of 43 cases (84%).
  • US localized the abnormal gland to the specific quadrant (34/43 cases [79%] sensitivity versus 23/43 cases [53%] sensitivity using sestamibi scan alone to localize to the specific quadrant, P = .03).
  • CONCLUSION: It is clear that the combined modalities of office-based US and sestamibi scintigraphy in preoperative localization have a high success rate and should be considered in parathyroid surgery.
  • [MeSH-major] Adenoma / ultrasonography. Hyperparathyroidism, Primary / ultrasonography. Parathyroid Neoplasms / ultrasonography

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16490537.001).
  • [ISSN] 0002-9610
  • [Journal-full-title] American journal of surgery
  • [ISO-abbreviation] Am. J. Surg.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


8. Zhou JP, Zhang H, Dong M, Kong FM, Tian YL, Liu YF: [Surgical treatment of asymptomatic primary hyperparathyroidism]. Zhonghua Wai Ke Za Zhi; 2008 Oct 1;46(19):1483-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Surgical treatment of asymptomatic primary hyperparathyroidism].
  • OBJECTIVE: To discuss the diagnosis and management of asymptomatic primary hyperparathyroidism (PHPT).
  • METHODS: Clinical data of 46 cases of primary hyperparathyroidism from January 1990 to December 2006 were retrospectively analyzed.
  • Three out of the 5 cases obtained the diagnosis by routine health examination and 1 case was misdiagnosed as thyroid tumor before surgery, but was conformed as parathyroid adenoma by intraoperative biopsy.
  • The serum calcium and the parathyroid hormone (PTH) levels were elevated in 4 cases, while only 1 being normal range.
  • All patients had the same pathological diagnosis as parathyroid adenomas.
  • CONCLUSIONS: Asymptomatic primary hyperparathyroidism could be diagnosed according to co-elevated serum calcemia and PTH without typical symptoms.
  • [MeSH-major] Hyperparathyroidism, Primary / diagnosis. Hyperparathyroidism, Primary / surgery

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19094627.001).
  • [ISSN] 0529-5815
  • [Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]
  • [ISO-abbreviation] Zhonghua Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  •  go-up   go-down


9. Rodosskaia NK, Orlova II, Brazhnikova VV: [Hyperparathyroidism in patients on long-term hemodialysis]. Klin Med (Mosk); 2009;87(4):68-70
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Hyperparathyroidism in patients on long-term hemodialysis].
  • The author presents case reports of parathyroid adenomas in patients receiving long-term hemodialysis and emphasizes the necessity of dynamic monitoring phosphorus-calcium and bone metabolism starting from the pre-dialysis phase of chronic renal insufficiency.
  • Preventive treatment and therapy of secondary hyperparathyroidism should be based on calcium-containing and phosphate-binding preparations and alfacalcidol at doses adjusted to individual requirements of the patients.
  • [MeSH-major] Hyperparathyroidism, Secondary / etiology. Renal Dialysis. Renal Insufficiency, Chronic / complications

  • MedlinePlus Health Information. consumer health - Chronic Kidney Disease.
  • MedlinePlus Health Information. consumer health - Dialysis.
  • Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .
  • Hazardous Substances Data Bank. PHOSPHORUS, ELEMENTAL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19514326.001).
  • [ISSN] 0023-2149
  • [Journal-full-title] Klinicheskaia meditsina
  • [ISO-abbreviation] Klin Med (Mosk)
  • [Language] rus
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
  • [Chemical-registry-number] 27YLU75U4W / Phosphorus; SY7Q814VUP / Calcium
  •  go-up   go-down


10. Hunt JL, Carty SE, Yim JH, Murphy J, Barnes L: Allelic loss in parathyroid neoplasia can help characterize malignancy. Am J Surg Pathol; 2005 Aug;29(8):1049-55
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Allelic loss in parathyroid neoplasia can help characterize malignancy.
  • Parathyroid carcinoma can be difficult to diagnose, and the final pathologic diagnosis relies on clinicopathologic correlation.
  • Clinical features of malignancy include high preoperative calcium levels and an intraoperative impression that the gland is adherent to local structures.
  • This study used molecular genotyping to assess parathyroid neoplasia for loss of heterozygosity across a panel of known tumor suppressor genes that have been previously identified as being important in the pathogenesis of parathyroid diseases.
  • Parathyroid adenomas, hyperplasia, and carcinomas were included in the study, and a fractional allelic loss was calculated for each lesion.
  • In addition, almost all adenomas and carcinomas had loss of the markers for 1p.
  • The benign parathyroid diseases (adenomas and hyperplasia) had low mean fractional allelic loss (11% and 15%, respectively).
  • The parathyroid carcinomas, in contrast, showed high mean fractional allelic loss (63%).
  • This difference in the mutational profile suggests that this type of assay may be useful as an adjunctive diagnostic test in cases of parathyroid neoplasia.
  • [MeSH-major] Loss of Heterozygosity / genetics. Parathyroid Neoplasms / genetics
  • [MeSH-minor] Adenoma / genetics. Carcinoma / genetics. Humans. Hyperparathyroidism / genetics. Hyperparathyroidism / pathology. Hyperplasia. Neoplasm Invasiveness

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16006799.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


11. Sugino K, Ito K, Nagahama M, Kitagawa W, Shibuya H, Ohkuwa K, Yano Y, Ito K: Minimally invasive surgery for primary hyperparathyroidism with or without intraoperative parathyroid hormone monitoring. Endocr J; 2010;57(11):953-8
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Minimally invasive surgery for primary hyperparathyroidism with or without intraoperative parathyroid hormone monitoring.
  • We analyzed the utility of intraoperative parathyroid hormone (IOPTH) monitoring in minimally invasive surgery for primary hyperparathyroidism (pHPT).
  • A group who underwent surgery without IOPTH monitoring (Group 1; n=87), and a group who underwent surgery with IOPTH monitoring (Group 2; n=80), in which IOPTH was measured at 5, 10, 15 minutes after excision of the abnormal parathyroid gland.
  • An enlarged parathyroid gland that was consistent with the results of a preoperative imaging study was found in 84 patients (96.6%).
  • Two of these patients were found to have had double adenomas, one on each side, during the initial surgery.
  • [MeSH-major] Hyperparathyroidism, Primary / blood. Hyperparathyroidism, Primary / surgery. Parathyroid Hormone / blood. Parathyroidectomy / methods

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20823623.001).
  • [ISSN] 1348-4540
  • [Journal-full-title] Endocrine journal
  • [ISO-abbreviation] Endocr. J.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Parathyroid Hormone
  •  go-up   go-down


12. Choi H, Kim S, Moon JH, Lee YH, Rhee Y, Kang ES, Ahn CW, Cha BS, Lee EJ, Kim KR, Lee HC, Jeong SY, Kim HJ, Lim SK: Multiple endocrine neoplasia type 1 with multiple leiomyomas linked to a novel mutation in the MEN1 gene. Yonsei Med J; 2008 Aug 30;49(4):655-61
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • MEN1 is characterized by the presence of functioning and nonfunctioning tumors or hyperplasia of the pituitary gland, parathyroid glands, and pancreatic islet cells.
  • Biochemical abnormalities included hypercalcemia with elevated parathyroid hormone.
  • This is the first case of MEN1 accompanied with multiple leiomyomas, parathyroid adenoma, pituitary adenoma, pancreatic tumor, and adrenal tumor.


13. Rubello D, Gross MD, Mariani G, AL-Nahhas A: Scintigraphic techniques in primary hyperparathyroidism: from pre-operative localisation to intra-operative imaging. Eur J Nucl Med Mol Imaging; 2007 Jun;34(6):926-33
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Scintigraphic techniques in primary hyperparathyroidism: from pre-operative localisation to intra-operative imaging.
  • INTRODUCTION: Primary hyperparathyroidism (PHPT) is an increasingly diagnosed disease worldwide.
  • In most cases, PHPT is related to the presence of a solitary parathyroid adenoma (PA).
  • [MeSH-major] Hyperparathyroidism, Primary / diagnosis. Hyperparathyroidism, Primary / diagnostic imaging. Radionuclide Imaging / methods
  • [MeSH-minor] Adenoma / metabolism. Diffusion. Humans. Image Processing, Computer-Assisted. Neck / pathology. Parathyroid Glands / metabolism. Parathyroid Neoplasms / metabolism. Parathyroidectomy. Radiopharmaceuticals / pharmacology. Sensitivity and Specificity. Technetium Tc 99m Sestamibi / pharmacology. Tomography, Emission-Computed, Single-Photon / methods

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • MedlinePlus Health Information. consumer health - Nuclear Scans.
  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Eur J Nucl Med Mol Imaging. 2008 Jan;35(1):219-20 [17926034.001]
  • [Cites] Eur J Nucl Med. 2001 Sep;28(9):1351-9 [24578055.001]
  • [Cites] Surgery. 1997 Dec;122(6):1107-14; discussion 1114-6 [9426426.001]
  • [Cites] Eur J Surg Oncol. 2000 Dec;26(8):785-8 [11087646.001]
  • [Cites] Radiology. 2000 Feb;214(2):393-402 [10671586.001]
  • [Cites] World J Surg. 1996 Sep;20(7):835-9; discussion 839-40 [8678959.001]
  • [Cites] Eur J Nucl Med. 1997 Mar;24(3):246-51 [9143460.001]
  • [Cites] Radiology. 2001 Mar;218(3):783-90 [11230657.001]
  • [Cites] J Nucl Med. 1998 Sep;39(9):1617-20 [9744355.001]
  • [Cites] Eur J Nucl Med. 2000 Sep;27(9):1300-4 [11007510.001]
  • [Cites] Int J Mol Med. 2005 Aug;16(2):215-9 [16012752.001]
  • [Cites] J Nucl Med. 1998 Feb;39(2):320-4 [9476944.001]
  • [Cites] Eur J Nucl Med. 1995 Jun;22(6):556-8 [7556303.001]
  • [Cites] Surg Clin North Am. 1995 Jun;75(3):483-98 [7747254.001]
  • [Cites] Nucl Med Commun. 2003 Feb;24(2):133-40 [12548037.001]
  • [Cites] J Nucl Med. 1998 Oct;39(10):15N, 24N [9776261.001]
  • [Cites] Nucl Med Commun. 2005 Feb;26(2):133-6 [15657506.001]
  • [Cites] J Nucl Med. 1992 Oct;33(10 ):1801-7 [1328564.001]
  • [Cites] Surgery. 2001 Dec;130(6):1011-8 [11742331.001]
  • [Cites] Clin Radiol. 2004 Nov;59(11):967-76 [15488844.001]
  • [Cites] J Nucl Med. 1992 Mar;33(3):313-8 [1531500.001]
  • [Cites] Panminerva Med. 2002 Jun;44(2):99-105 [12032427.001]
  • [Cites] Ann Surg. 2000 May;231(5):732-42 [10767795.001]
  • [Cites] J Nucl Med. 1998 Jun;39(6):1100-5 [9627353.001]
  • [Cites] Eur J Nucl Med. 2000 May;27(5):485-9 [10853801.001]
  • [Cites] N Engl J Med. 1980 Jan 24;302(4):189-93 [7350459.001]
  • [Cites] Surgery. 1998 Dec;124(6):1088-92; discussion 1092-3 [9854588.001]
  • [Cites] Laryngoscope. 1998 May;108(5):627-9 [9591536.001]
  • [Cites] Q J Nucl Med. 2003 Jun;47(2):129-38 [12865873.001]
  • [Cites] J Nucl Med. 1996 Nov;37(11):1809-15 [8917180.001]
  • [Cites] Clin Radiol. 1990 Apr;41(4):239-43 [2187649.001]
  • [Cites] J Nucl Med. 1996 Nov;37(11):1766-70 [8917171.001]
  • [Cites] Thyroid. 2002 Jan;12 (1):53-61 [11838731.001]
  • [Cites] Nucl Med Commun. 1989 Nov;10 (11):791-4 [2532313.001]
  • [Cites] Int J Mol Med. 2004 Oct;14(4):595-9 [15375587.001]
  • [Cites] J Nucl Med. 1996 May;37(5):798-804 [8965148.001]
  • [Cites] J Nucl Med. 2005 Feb;46(2):248-52 [15695783.001]
  • [Cites] J Clin Endocrinol Metab. 2002 Mar;87(3):1024-9 [11889156.001]
  • [Cites] J Am Coll Surg. 1998 Mar;186(3):293-305 [9510260.001]
  • [Cites] Invest Radiol. 2000 Aug;35(8):453-9 [10946972.001]
  • [Cites] Arch Surg. 2002 Sep;137(9):1055-9 [12215160.001]
  • [Cites] Radiol Clin North Am. 2000 Sep;38(5):1105-29 [11054972.001]
  • [Cites] Eur J Nucl Med Mol Imaging. 2003 Feb;30(2):193-6 [12552335.001]
  • [Cites] Surgery. 1999 Dec;126(6):1016-21; discussion 1021-2 [10598182.001]
  • [Cites] Mayo Clin Proc. 1984 Aug;59(8):534-7 [6087039.001]
  • [Cites] Ann Acad Med Singapore. 1998 Mar;27(2):192-5 [9663308.001]
  • [Cites] Endocrinol Metab Clin North Am. 1989 Sep;18(3):659-700 [2673767.001]
  • [Cites] AJR Am J Roentgenol. 1997 Dec;169(6):1671-4 [9393188.001]
  • [Cites] Postgrad Med J. 1990 Jun;66(776):441-5 [2170959.001]
  • [Cites] J Nucl Med. 2004 Jan;45(1):40-8 [14734671.001]
  • [Cites] Surgery. 1997 Dec;122(6):998-1003; discussion 1003-4 [9426412.001]
  • [Cites] J Nucl Med. 1995 Feb;36(2):241-3 [7830122.001]
  • [Cites] AJR Am J Roentgenol. 1998 Apr;170(4):1097-103 [9530067.001]
  • [Cites] Eur J Nucl Med Mol Imaging. 2003 Feb;30(2):189-2 [12643287.001]
  • [Cites] J Nucl Med. 1996 Nov;37(11):1773-8 [8917173.001]
  • [Cites] Eur J Nucl Med. 1994 Jan;21(1):17-22 [8088281.001]
  • [Cites] Arch Surg. 2004 Dec;139(12):1331-8 [15613292.001]
  • [Cites] J Am Coll Surg. 2000 Jul;191(1):24-31 [10898180.001]
  • [Cites] Clin Nucl Med. 2000 Jul;25(7):527-31 [10885694.001]
  • [Cites] Radiology. 1987 Jan;162(1 Pt 1):133-7 [3538145.001]
  • [Cites] Acta Chir Scand. 1990 Jan;156(1):29-35 [2108524.001]
  • [Cites] Br J Radiol. 1997 May;70(833):459-64 [9227226.001]
  • [Cites] Invest Radiol. 1997 Aug;32(8):459-65 [9258734.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 1996 Apr;122(4):369-74 [8600920.001]
  • [Cites] Eur J Nucl Med. 2001 Sep;28(9):1409-20 [11585302.001]
  • [Cites] Int J Mol Med. 2006 May;17(5):779-83 [16596260.001]
  • [Cites] Surgery. 1999 Dec;126(6):993-7 [10598178.001]
  • [Cites] Ann Surg. 1992 Apr;215(4):300-17 [1558410.001]
  • (PMID = 17351774.001).
  • [ISSN] 1619-7070
  • [Journal-full-title] European journal of nuclear medicine and molecular imaging
  • [ISO-abbreviation] Eur. J. Nucl. Med. Mol. Imaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


14. Koulouris G, Pianta M, Stuckey S: The 'sentinel clot' sign in spontaneous retropharyngeal hematoma secondary to parathyroid apoplexy. Ear Nose Throat J; 2006 Sep;85(9):606-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The 'sentinel clot' sign in spontaneous retropharyngeal hematoma secondary to parathyroid apoplexy.
  • Spontaneous retropharyngeal hemorrhage from a cervical parathyroid adenoma is a rare complication of primary hyperparathyroidism.
  • Awareness of a possible thyroid or parathyroid etiology may expedite treatment and prevent unnecessary interventions.
  • [MeSH-major] Adenoma / complications. Hematoma / etiology. Parathyroid Neoplasms / complications. Retroperitoneal Space

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17044430.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


15. Yun JS, Nam KH, Chung WY, Park CS: Giant posterior mediastinal parathyroid adenoma. Thyroid; 2008 Apr;18(4):475-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant posterior mediastinal parathyroid adenoma.
  • [MeSH-major] Adenoma / diagnosis. Mediastinum / pathology. Parathyroid Neoplasms / diagnosis
  • [MeSH-minor] Calcium / metabolism. Female. Humans. Middle Aged. Parathyroid Hormone / metabolism. Parathyroidectomy. Technetium Tc 99m Sestamibi / pharmacology. Time Factors. Tomography, Emission-Computed, Single-Photon / methods. Tomography, X-Ray Computed / methods. Treatment Outcome

  • Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18399771.001).
  • [ISSN] 1050-7256
  • [Journal-full-title] Thyroid : official journal of the American Thyroid Association
  • [ISO-abbreviation] Thyroid
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Parathyroid Hormone; 971Z4W1S09 / Technetium Tc 99m Sestamibi; SY7Q814VUP / Calcium
  •  go-up   go-down


16. Toniato A, Pelizzo MR: Letter 1: Intraoperative diagnosis and treatment of parathyroid cancer and atypical parathyroid adenoma (Br J Surg 2007; 94: 566-570). Br J Surg; 2007 Aug;94(8):1042-3; author reply 1043-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Letter 1: Intraoperative diagnosis and treatment of parathyroid cancer and atypical parathyroid adenoma (Br J Surg 2007; 94: 566-570).
  • [MeSH-major] Adenoma / diagnosis. Parathyroid Neoplasms / diagnosis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentOn] Br J Surg. 2007 May;94(5):566-70 [17380564.001]
  • (PMID = 17636521.001).
  • [ISSN] 0007-1323
  • [Journal-full-title] The British journal of surgery
  • [ISO-abbreviation] Br J Surg
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] England
  •  go-up   go-down


17. Guerrero MA, Wray CJ, Kee SS, Frenzel JC, Perrier ND: Minimally invasive parathyroidectomy complicated by pneumothoraces: a report of 4 cases. J Surg Educ; 2007 Mar-Apr;64(2):101-7; discussion 113
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The traditional approach to primary hyperparathyroidism has been a bilateral neck exploration for evaluation of all four parathyroid glands.
  • With the advent of minimally invasive surgery, minimally invasive parathyroidectomy has become a popular approach for the treatment of parathyroid adenomas.
  • Additional risks in three patients were dissection in the superior mediastinum, traction on the thyrothymic ligament, and a low-lying inferior parathyroid gland.
  • [MeSH-minor] Adenoma / surgery. Adult. Aged. Anesthesia, Intravenous. Dissection. Electrocoagulation. Female. Humans. Hyperparathyroidism / surgery. Intraoperative Complications. Ligaments / injuries. Mediastinum / surgery. Middle Aged. Minimally Invasive Surgical Procedures. Parathyroid Glands / pathology. Parathyroid Neoplasms / surgery. Postoperative Complications. Posture. Respiration. Risk Factors

  • MedlinePlus Health Information. consumer health - Collapsed Lung.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17462211.001).
  • [ISSN] 1931-7204
  • [Journal-full-title] Journal of surgical education
  • [ISO-abbreviation] J Surg Educ
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


18. Papathanassiou D, Flament JB, Pochart JM, Patey M, Marty H, Liehn JC, Schvartz C: SPECT/CT in localization of parathyroid adenoma or hyperplasia in patients with previous neck surgery. Clin Nucl Med; 2008 Jun;33(6):394-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] SPECT/CT in localization of parathyroid adenoma or hyperplasia in patients with previous neck surgery.
  • It has proved useful for localization of abnormal parathyroid glands, especially in the case of an ectopic gland.
  • MATERIALS AND METHODS: Four patients with prior neck surgery and hyperparathyroidism underwent parathyroid Tc-99m MIBI scintigraphy with SPECT/CT.
  • Two patients had undergone surgery for hyperparathyroidism and 2 had undergone thyroidectomy, 1 for thyroid cancer and 1 for multinodular goiter.
  • Parathyroid hormone levels were assessed during surgery, and patients were followed several months after treatment.
  • RESULTS: SPECT/CT successfully localized the abnormal gland, including an uncommon anterior situation for which previous surgery guided by planar imagery failed to cure the hyperparathyroidism.
  • It allowed efficient surgical treatment, as confirmed by parathyroid hormone level normalization, without complications and with a relatively short operation time in those challenging cases.
  • CONCLUSIONS: SPECT/CT seems to be a useful tool for presurgical assessment in hyperparathyroidism, not only for ectopic glands but also for patients with previous neck surgery.
  • [MeSH-major] Adenoma / diagnosis. Adenoma / surgery. Parathyroid Neoplasms / diagnosis. Parathyroid Neoplasms / surgery. Thyroidectomy. Tomography, Emission-Computed, Single-Photon / methods. Tomography, X-Ray Computed / methods

  • MedlinePlus Health Information. consumer health - CT Scans.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18496444.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


19. Chien D, Jacene H: Imaging of parathyroid glands. Otolaryngol Clin North Am; 2010 Apr;43(2):399-415, x
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Imaging of parathyroid glands.
  • Preoperative imaging studies have an important role in facilitating successful localization of adenomas for surgeons.
  • Based on findings that scintigraphy is reported to have the highest accuracy for localization of adenomas when compared with anatomic imaging techniques, this article discusses the current role and limitations of imaging, with a focus on scintigraphy, in the evaluation of patients before surgery for hyperparathyroidism.
  • [MeSH-major] Adenoma / diagnosis. Diagnostic Imaging. Parathyroid Neoplasms / diagnosis
  • [MeSH-minor] Humans. Hyperparathyroidism, Primary / diagnosis. Hyperparathyroidism, Primary / pathology. Hyperparathyroidism, Primary / surgery. Minimally Invasive Surgical Procedures. Parathyroid Glands / pathology. Parathyroidectomy. Sensitivity and Specificity. Surgery, Computer-Assisted

  • MedlinePlus Health Information. consumer health - Diagnostic Imaging.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20510723.001).
  • [ISSN] 1557-8259
  • [Journal-full-title] Otolaryngologic clinics of North America
  • [ISO-abbreviation] Otolaryngol. Clin. North Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 94
  •  go-up   go-down


20. Schachter PP, Ayesh S, Matouk I, Schneider T, Czerniak A, Hochberg A: Differential expression of kinase genes in primary hyperparathyroidism: adenoma versus normal and hyperplastic parathyroid tissue. Arch Pathol Lab Med; 2007 Jan;131(1):126-30
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Differential expression of kinase genes in primary hyperparathyroidism: adenoma versus normal and hyperplastic parathyroid tissue.
  • CONTEXT: Differentiation between adenoma and hyperplasia or even normal parathyroid tissue is difficult and based mainly on the surgeon's skill.
  • Exploration of genes that express differentially in these various tissues using microarrays and other sophisticated research tools will enable identification and perhaps development of new methods of perioperative diagnosis.
  • OBJECTIVE: To assemble a panel of kinase genes to differentiate parathyroid adenoma from normal and hyperplastic parathyroid tissue.
  • DESIGN: RNA was extracted from adenoma, hyperplasia, and normal parathyroid tissue and hybridized to a microarray containing 359 human cDNAs of known kinase genes.
  • RESULTS: The ratio values considered significant (<0.5 or >1.5) suggest that genes up-regulated in parathyroid adenoma are those responsible for blood vessel angiogenesis and genes belonging to the cyclin-dependent kinase inhibitor groups.
  • Genes down-regulated in parathyroid adenoma are related to cellular growth and apoptosis--genes from the mitogen-activated protein kinase group and DNA-dependent protein kinase group.
  • An interesting gene down-regulated in the parathyroid adenoma samples is related to the serine/threonine protein kinases that exert a key function in calcium handling.
  • CONCLUSIONS: The kinase genes panel presented can be used to differentiate parathyroid adenoma from normal and hyperplastic parathyroid tissue in particular when histopathology fails to provide a decisive diagnosis.
  • [MeSH-major] Adenoma / genetics. Hyperparathyroidism, Primary / genetics. Parathyroid Neoplasms / genetics. Phosphotransferases / genetics

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17227113.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] EC 2.7.- / Phosphotransferases
  •  go-up   go-down


21. Johnson NA, Yip L, Tublin ME: Cystic parathyroid adenoma: sonographic features and correlation with 99mTc-sestamibi SPECT findings. AJR Am J Roentgenol; 2010 Dec;195(6):1385-90
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cystic parathyroid adenoma: sonographic features and correlation with 99mTc-sestamibi SPECT findings.
  • OBJECTIVE: The purpose of this study was to describe the typical ultrasound features of cystic parathyroid adenoma.
  • MATERIALS AND METHODS: A review of a surgical database and electronic medical records from 2006 to 2009 identified the cases of 15 patients who underwent preoperative cervical sonography for primary hyperparathyroidism with subsequent resection of pathologically proven parathyroid adenoma with predominantly cystic components.
  • Technetium-99m-sestamibi SPECT findings, surgical and pathologic reports, and the results of parathyroid hormone assay of the cyst fluid also were reviewed.
  • RESULTS: Most of the cystic adenomas (14/15, 93%) were deep or inferolateral to the adjacent thyroid.
  • An echogenic border separating the adenoma from the overlying thyroid was identified in 9 of 15 patients (60%).
  • Six of 14 patients underwent preoperative or intraoperative sampling of cyst fluid, and the assay showed the parathyroid hormone levels ranged from 1,198 to greater than 5,000 pg/mL.
  • Fourteen of 15 patients underwent preoperative sestamibi SPECT, and the adenoma was definitively localized in four patients (29%).
  • CONCLUSION: Awareness of typical sonographic features (location, color Doppler vascularity) may aid radiologists in preoperative localization of parathyroid adenomas, even when cystic degeneration occurs.
  • In cases in which imaging or clinical features are equivocal, the results of cyst fluid sampling and parathyroid hormone assay are confirmatory.
  • [MeSH-major] Adenoma / radionuclide imaging. Adenoma / ultrasonography. Parathyroid Neoplasms / radionuclide imaging. Parathyroid Neoplasms / ultrasonography. Tomography, Emission-Computed, Single-Photon. Ultrasonography, Doppler, Color
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Hyperparathyroidism, Primary / etiology. Male. Middle Aged. Radiopharmaceuticals. Retrospective Studies. Technetium Tc 99m Sestamibi

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21098199.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


22. Shah S, Win Z, Al-Nahhas A: Multimodality imaging of the parathyroid glands in primary hyperparathyroidism. Minerva Endocrinol; 2008 Sep;33(3):193-202
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multimodality imaging of the parathyroid glands in primary hyperparathyroidism.
  • Primary hyperparathyroidism is a common endocrine disorder, affecting approximately 1 in 500 women and 1 in 2,000 men.
  • Surgical removal of the hyperfunctioning parathyroid gland is the primary curative treatment.
  • The last decade has witnessed the development of minimally invasive parathyroidectomy, which is based on the fact that the vast majority of cases are caused by single adenomas.
  • However, the success of this technique relies on accurate preoperative localisation of the parathyroid lesions.
  • Ultrasound and 99mTc sestamibi scintigraphy, particularly when complemented by single photon emission computed tomography (SPECT), are currently the imaging techniques of choice for preoperative localisation of parathyroid adenomas; a combination of the two methods further improves the sensitivity and accuracy of detection.
  • MRI appears to be useful in patients with persistent or recurrent hyperparathyroidism, who have previously undergone surgery.
  • [MeSH-major] Adenoma / radionuclide imaging. Diagnostic Imaging / methods. Hyperparathyroidism / radionuclide imaging. Parathyroid Neoplasms / radionuclide imaging
  • [MeSH-minor] Female. Humans. Magnetic Resonance Imaging. Male. Parathyroid Glands / embryology. Parathyroid Glands / physiopathology. Parathyroidectomy. Preoperative Care. Radiopharmaceuticals. Sensitivity and Specificity. Subtraction Technique. Technetium Tc 99m Sestamibi. Tomography, Emission-Computed, Single-Photon. Tomography, X-Ray Computed

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • MedlinePlus Health Information. consumer health - Diagnostic Imaging.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18846025.001).
  • [ISSN] 0391-1977
  • [Journal-full-title] Minerva endocrinologica
  • [ISO-abbreviation] Minerva Endocrinol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  • [Number-of-references] 55
  •  go-up   go-down


23. Yip L, Pryma DA, Yim JH, Virji MA, Carty SE, Ogilvie JB: Can a lightbulb sestamibi SPECT accurately predict single-gland disease in sporadic primary hyperparathyroidism? World J Surg; 2008 May;32(5):784-92; discussion 793-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Can a lightbulb sestamibi SPECT accurately predict single-gland disease in sporadic primary hyperparathyroidism?
  • BACKGROUND: Technetium-99m sestamibi scintigraphy with single photon emission computed tomography (SPECT) is widely used to guide minimally invasive exploration in patients with sporadic primary hyperparathyroidism (SPH), although its sensitivity in multiglandular disease is limited.
  • METHODS: Prospectively entered data from 764 patients with SPH treated with initial parathyroid exploration from March 5, 2000, to December 31, 2006, were reviewed.
  • Clinical findings were compared among LBS patients with a single adenoma (true positive) and LBS patients with multiglandular disease (false negative).
  • RESULTS: One hundred fifty of 167 (89.8%) LBS patients had a single adenoma and 3 (1.8%) had carcinoma.
  • Parathyroid hyperplasia occurred less frequently in LBS patients [5/167 (3%)] compared with non-LBS patients [36/418 (8.6%)], (p=0.02), while double adenomas occurred equally often in LBS patients [9/167 (5.4%)] compared with non-LBS patients [24/418 (5.7%)], (p=0.87).
  • Double adenomas in LBS patients were more likely ipsilateral (7/9, p=0.005) and left-sided (7/7, p=0.008).
  • To avoid unacceptable rates of failure at initial parathyroid exploration, the expert surgeon should use validated adjuncts such as intraoperative PTH monitoring or four-gland exploration.
  • [MeSH-major] Adenoma / diagnostic imaging. Hyperparathyroidism, Primary / diagnostic imaging. Parathyroid Neoplasms / diagnostic imaging. Radiopharmaceuticals. Technetium Tc 99m Sestamibi. Tomography, Emission-Computed, Single-Photon

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Surgery. 1997 Dec;122(6):1107-14; discussion 1114-6 [9426426.001]
  • [Cites] J Nucl Med. 2007 Jul;48(7):1084-9 [17574983.001]
  • [Cites] Surgery. 1994 Dec;116(6):954-7; discussion 957-8 [7985102.001]
  • [Cites] Surgery. 2003 Dec;134(6):995-1003; discussion 1003-4 [14668733.001]
  • [Cites] Surgery. 2006 Sep;140(3):418-22 [16934604.001]
  • [Cites] Surg Oncol Clin N Am. 1998 Oct;7(4):721-48 [9735131.001]
  • [Cites] Surgery. 2002 Dec;132(6):1086-92; discussion 1092-3 [12490859.001]
  • [Cites] Semin Nucl Med. 2005 Oct;35(4):266-76 [16150247.001]
  • [Cites] Ann Surg. 2005 Sep;242(3):375-80; discussion 380-3 [16135923.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 2005 Jun;131(6):493-8 [15967881.001]
  • [Cites] Surgery. 2004 Oct;136(4):872-80 [15467674.001]
  • [Cites] J Nucl Med. 1996 May;37(5):798-804 [8965148.001]
  • [Cites] World J Surg. 2004 Nov;28(11):1132-8 [15490068.001]
  • [Cites] Arch Surg. 2004 May;139(5):501-6; discussion 506-7 [15136350.001]
  • [Cites] Arch Surg. 2007 Apr;142(4):381-6 [17441292.001]
  • [Cites] J Am Coll Surg. 2003 Nov;197(5):739-46 [14585407.001]
  • [Cites] Arch Surg. 2006 Aug;141(8):777-82; discussion 782 [16924085.001]
  • [Cites] World J Surg. 2004 Nov;28(11):1127-31 [15490069.001]
  • [Cites] Surgery. 2002 Feb;131(2):149-57 [11854692.001]
  • [Cites] World J Surg. 1991 Nov-Dec;15(6):688-92 [1767534.001]
  • [Cites] Surgery. 2006 Dec;140(6):856-63; discussion 863-5 [17188131.001]
  • [Cites] J Nucl Med. 1996 Nov;37(11):1773-8 [8917173.001]
  • [Cites] Surgery. 2001 Jun;129(6):720-9 [11391371.001]
  • [Cites] Br J Radiol. 1991 Jan;64(757):1-4 [1847837.001]
  • [Cites] Surgery. 2004 Dec;136(6):1154-9 [15657570.001]
  • [Cites] World J Surg. 2006 Jan;30(1):76-83 [16369710.001]
  • [Cites] Arch Surg. 2002 Aug;137(8):967-70 [12147000.001]
  • [Cites] Ann Surg. 2002 May;235(5):665-70; discussion 670-2 [11981212.001]
  • [Cites] J Am Coll Surg. 2006 May;202(5):715-22 [16648010.001]
  • [Cites] Radiology. 1996 Oct;201(1):85-91 [8816526.001]
  • [Cites] World J Surg. 2006 May;30(5):697-704 [16680585.001]
  • [Cites] Ann Surg. 1992 Apr;215(4):300-17 [1558410.001]
  • [Cites] J Am Coll Surg. 2006 Jan;202(1):18-24 [16377493.001]
  • [Cites] J Am Coll Surg. 2007 Feb;204(2):286-90 [17254933.001]
  • (PMID = 18324345.001).
  • [ISSN] 0364-2313
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


24. Takashima S, Nakano H, Minamoto K, Misao T, Shiota K: A thoracoscopically resected case of mediastinal parathyroid cyst. Acta Med Okayama; 2005 Aug;59(4):165-70
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A thoracoscopically resected case of mediastinal parathyroid cyst.
  • The pathological findings were compatible with benign parathyroid cyst, which was suspected to be the cystic degeneration of a parathyroid adenoma.
  • [MeSH-major] Mediastinal Neoplasms / surgery. Parathyroid Neoplasms / surgery. Thoracoscopy

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16155643.001).
  • [ISSN] 0386-300X
  • [Journal-full-title] Acta medica Okayama
  • [ISO-abbreviation] Acta Med. Okayama
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


25. Yeşilkaya E, Cinaz P, Bideci A, Camurdan O, Demirel F, Demircan S: Hungry bone syndrome after parathyroidectomy caused by an ectopic parathyroid adenoma. J Bone Miner Metab; 2009;27(1):101-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hungry bone syndrome after parathyroidectomy caused by an ectopic parathyroid adenoma.
  • Hungry bone syndrome (HBS), i.e., persistent hypocalcemia and hypophosphatemia as a result of extensive remineralization, is rarely encountered in children after parathyroid surgery.
  • Herein, we report a 12-year-old girl who was diagnosed to have an ectopic parathyroid adenoma, and HBS was observed in the postsurgical follow-up.
  • The diagnosis and the risk factors are discussed in the light of the literature.
  • [MeSH-major] Hypocalcemia / etiology. Hypophosphatemia / etiology. Parathyroid Neoplasms / complications. Parathyroid Neoplasms / surgery. Parathyroidectomy / adverse effects
  • [MeSH-minor] Child. Female. Humans. Syndrome. Thymus Gland / pathology. Thymus Gland / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] N Engl J Med. 2007 Jul 19;357(3):266-81 [17634462.001]
  • [Cites] Medicine (Baltimore). 1992 Jul;71(4):197-205 [1518393.001]
  • [Cites] J Bone Miner Res. 2002 Aug;17(8):1498-511 [12162504.001]
  • [Cites] World J Surg Oncol. 2004 Nov 30;2:41 [15571624.001]
  • [Cites] Endocr J. 2004 Feb;51(1):75-81 [15004412.001]
  • [Cites] J Radiol. 2003 Dec;84(12 Pt 1):1969-73 [14710047.001]
  • [Cites] J Pediatr Surg. 1992 Dec;27(12 ):1502-3 [1469551.001]
  • [Cites] Am J Kidney Dis. 2005 Jun;45(6):e109-14 [15957122.001]
  • [Cites] J Clin Endocrinol Metab. 1995 Mar;80(3):729-34 [7883824.001]
  • [Cites] Eur J Surg. 2002;168(12):747-9 [15362589.001]
  • [Cites] Am J Manag Care. 2007 Dec;13 Suppl 11:S290-308; quiz S309-12 [18095779.001]
  • [Cites] J Bone Miner Metab. 2006;24(4):349-52 [16816931.001]
  • [Cites] J Clin Densitom. 2006 Jan-Mar;9(1):84-90 [16731436.001]
  • [Cites] Am J Med. 1988 Apr;84(4):654-60 [3400660.001]
  • [Cites] Ann Surg. 1981 Jun;193(6):805-9 [7247524.001]
  • [Cites] Osteoporos Int. 2005 Jul;16(7):713-6 [15776217.001]
  • [Cites] Clin Endocrinol (Oxf). 1998 Apr;48(4):435-43 [9640410.001]
  • [Cites] Arch Surg. 1988 Sep;123(9):1096-100 [3415460.001]
  • (PMID = 19057842.001).
  • [ISSN] 0914-8779
  • [Journal-full-title] Journal of bone and mineral metabolism
  • [ISO-abbreviation] J. Bone Miner. Metab.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


26. Gómez Palacios A, Gómez Zábala J, Gutiérrez MT, Expósito A, Barrios B, Zorraquino A, Taibo MA, Iturburu I: [Utility of methoxy isobutyl isonitrile (MIBI) scintigraphy, ultrasound and computerized axial tomography in preoperative topographic diagnosis of hiperparathyroidism]. Cir Esp; 2006 Dec;80(6):378-84
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Utility of methoxy isobutyl isonitrile (MIBI) scintigraphy, ultrasound and computerized axial tomography in preoperative topographic diagnosis of hiperparathyroidism].
  • [Transliterated title] Utilidad del MIBI, la ecografía y la tomografía computarizada en el diagnóstico topográfico preoperatorio del hiperparatiroidismo.
  • 3. To use its diagnostic reliability to determine whether selective approaches can be used to treat hyperparathyroidism (HPT).
  • The diagnosis was correct in all of the single images.
  • Multiple images were due to hyperplasia and parathyroid adenomas with thyroid disease (5.2%).
  • The sensitivity of US was 63% and allowed detection of three MIBI-negative adenomas (4%).
  • CAT was less sensitive (55%), but detected a further three MIBI-negative adenomas (4%).
  • [MeSH-major] Adenoma / diagnosis. Hyperparathyroidism / diagnosis. Parathyroid Neoplasms / diagnosis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biopsy. Diagnosis, Differential. Diagnostic Errors. Female. Humans. Hyperplasia / diagnosis. Male. Middle Aged. Neck / ultrasonography. Parathyroid Diseases. Parathyroid Glands / pathology. Radiopharmaceuticals / therapeutic use. Sensitivity and Specificity. Technetium Tc 99m Sestamibi. Tomography, X-Ray Computed. Whole Body Imaging

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17192222.001).
  • [ISSN] 0009-739X
  • [Journal-full-title] Cirugía española
  • [ISO-abbreviation] Cir Esp
  • [Language] spa
  • [Publication-type] Comparative Study; English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


27. Dinçer SI, Demir A, Kara HV, Günlüoglu MZ: Thoracoscopic removal of a maternal mediastinal ectopic parathyroid adenoma causing neonatal hypocalcemia: a case report. Ann Thorac Cardiovasc Surg; 2008 Oct;14(5):325-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Thoracoscopic removal of a maternal mediastinal ectopic parathyroid adenoma causing neonatal hypocalcemia: a case report.
  • Most parathyroid glands in hyperparathyroidism can be resected through a cervical approach.
  • In approximately 2% of cases, the ectopic gland is in the mediastinum in a location that requires a thoracic approach.
  • We describe a case involving a 29-year-old woman with hyperparathyroidism resulting from an ectopic mediastinal parathyroid adenoma that caused neonatal hypocalcemia, which was removed through VATS.
  • [MeSH-major] Adenoma / surgery. Choristoma / surgery. Hypocalcemia / etiology. Infant, Newborn, Diseases / etiology. Mediastinal Neoplasms / surgery. Parathyroid Glands. Parathyroid Neoplasms / surgery. Pregnancy Complications, Neoplastic / surgery. Thoracic Surgery, Video-Assisted
  • [MeSH-minor] Adult. Female. Humans. Hyperparathyroidism, Primary / etiology. Hyperparathyroidism, Primary / surgery. Infant, Newborn. Magnetic Resonance Imaging. Pregnancy. Tomography, Emission-Computed, Single-Photon. Treatment Outcome


28. Pai SI, Goldstein BJ, Studeman KD, Westra WH, Tufano RP: Concurrent sporadic parathyroid adenoma and carcinoma. Am J Otolaryngol; 2006 Sep-Oct;27(5):346-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Concurrent sporadic parathyroid adenoma and carcinoma.
  • [MeSH-major] Adenoma / diagnosis. Carcinoma / diagnosis. Neoplasms, Multiple Primary / diagnosis. Parathyroid Neoplasms / diagnosis
  • [MeSH-minor] Aged. Calcium / blood. Diagnosis, Differential. Humans. Male. Parathyroid Hormone / blood. Parathyroidectomy

  • Genetic Alliance. consumer health - Parathyroid carcinoma.
  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16935182.001).
  • [ISSN] 0196-0709
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Parathyroid Hormone; SY7Q814VUP / Calcium
  •  go-up   go-down


29. von Breitenbuch P, Iesalnieks I, Piso P, Schlitt HJ, Agha A: [Primary hyperparathyroidism: clinical symptoms, diagnostic significance and localisation--a retrospective analysis]. Zentralbl Chir; 2007 Dec;132(6):497-503
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary hyperparathyroidism: clinical symptoms, diagnostic significance and localisation--a retrospective analysis].
  • BACKGROUND: The primary hyperparathyroidism (pHPT) is one of the most frequent metabolic diseases.
  • Moreover, the question of the best localisation-diagnostics and the most frequent localisation of the adenoma is not yet clarified.
  • New operation strategies and more cost-efficient strategies for diagnostic and therapy could be developed due to the clinically established electrochemiluminescence immunoassay for intraoperative monitoring of intact parathyroid hormone (iPTH).
  • The best preoperative diagnostic procedure for localisation of the adenoma of the parathyroid gland, in non preoperated patients, seemed to be the combination of ultrasound and scintigraphy.
  • The most common localisation of the adenoma was caudal, on the left side.
  • Today, the combination of iPTH-monitoring and minimal invasive unilateral cervical exploration should be considered as standard in the surgery of the adrenal gland.
  • Due to our data we recommend an exploration of the left caudal parathyroid gland first if the localisation of the adenoma could not be clarified preoperatively.
  • [MeSH-major] Adenoma / diagnosis. Electrodiagnosis. Hyperparathyroidism, Primary / diagnosis. Luminescent Measurements. Monitoring, Intraoperative. Parathyroid Hormone / blood. Parathyroid Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Diagnostic Imaging. Female. Humans. Hyperparathyroidism, Secondary / blood. Hyperparathyroidism, Secondary / diagnosis. Hyperparathyroidism, Secondary / surgery. Male. Minimally Invasive Surgical Procedures. Postoperative Complications / blood. Postoperative Complications / etiology. Retrospective Studies

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [ErratumIn] Zentralbl Chir. 2008 Feb;133(1):85. Pompiliu, P [corrected to Piso, P]
  • (PMID = 18098076.001).
  • [ISSN] 0044-409X
  • [Journal-full-title] Zentralblatt für Chirurgie
  • [ISO-abbreviation] Zentralbl Chir
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Parathyroid Hormone
  •  go-up   go-down


30. Huang SC, Wu VC, Chou G, Huang TY, Lin SY, Sheu WH: Benign parathyroid adenoma presenting with unusual parathyroid crisis, anemia and myelofibrosis. J Formos Med Assoc; 2007 Feb;106(2 Suppl):S13-6
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign parathyroid adenoma presenting with unusual parathyroid crisis, anemia and myelofibrosis.
  • Although the clinical symptoms of patients with benign parathyroid adenoma are usually nonspecific and benign, a malignant presentation of the benign disease may sometimes occur.
  • Acute hypercalcemic crisis manifested and primary hyperparathyroidism was diagnosed together with myelofibrosis on account of the result of bone marrow biopsy.
  • Excision of a parathyroid adenoma was performed, and the anemia and bone marker regressed later.
  • These findings suggested that benign parathyroid adenoma may mimic the clinical presentation of parathyroid carcinoma, releasing excess parathyroid hormone and resulting in hyperparathyroid crisis.
  • In addition, primary hyperparathyroidism can be associated with anemia and myelofibrosis.

  • Genetic Alliance. consumer health - Anemia.
  • Genetic Alliance. consumer health - Myelofibrosis.
  • MedlinePlus Health Information. consumer health - Anemia.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17493890.001).
  • [ISSN] 0929-6646
  • [Journal-full-title] Journal of the Formosan Medical Association = Taiwan yi zhi
  • [ISO-abbreviation] J. Formos. Med. Assoc.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
  •  go-up   go-down


31. Casella C, Di Fabio F, Di Betta E, Nascimbeni R, Salerni B: [Surgical treatment of primary hyperparathyroidism: our experience]. Ann Ital Chir; 2008 Mar-Apr;79(2):121-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Surgical treatment of primary hyperparathyroidism: our experience].
  • The Authors report their experience on 136 patients with primary hyperparathyroidism.
  • Acute primary hyperparathyroidism was detected in 12 cases (8.8%).
  • 91.3% of the lesions were single adenoma, 7.3% double adenomas and 1.4% hyperplasia in MEN 1.
  • Surgical treatment was successful in 93.4% of cases ( 127/136 patients), increasing to 97.0% (132/136patients) if only recurrent hyperparathyroidism was considered, with no mortality and morbidity of 4.4%.
  • [MeSH-major] Hyperparathyroidism, Primary / surgery. Parathyroidectomy
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Parathyroid Glands / pathology. Parathyroid Hormone / blood

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18727275.001).
  • [ISSN] 0003-469X
  • [Journal-full-title] Annali italiani di chirurgia
  • [ISO-abbreviation] Ann Ital Chir
  • [Language] ita
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Parathyroid Hormone
  •  go-up   go-down


32. Goldstein RE, Carter WM 2nd, Fleming M, Bumpous J, Lentsch E, Rice M, Flynn M: Unilateral cervical surgical exploration aided by intraoperative parathyroid hormone monitoring in patients with primary hyperparathyroidism and equivocal sestamibi scan results. Arch Surg; 2006 Jun;141(6):552-7; discussion 557-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unilateral cervical surgical exploration aided by intraoperative parathyroid hormone monitoring in patients with primary hyperparathyroidism and equivocal sestamibi scan results.
  • HYPOTHESIS: Equivocal parathyroid technetium Tc 99m sestamibi scan results are likely to demonstrate the correct location for parathyroid adenomas.
  • DESIGN: Patients with primary hyperparathyroidism prospectively consented to participate in an institutional review board-approved study.
  • The parathyroid technetium Tc 99m sestamibi scan results were classified as positive, negative, or equivocal.
  • PATIENTS: Technetium Tc 99m sestamibi imaging was performed for 464 patients with primary hyperparathyroidism.
  • Eighty-four of these patients had scan results considered equivocal for unilateral adenomas.
  • The algorithm for this group of patients specified that they should receive an injection with technetium Tc 99m sestamibi prior to parathyroidectomy and that an intraoperative parathyroid hormone (iPTH) level decrease of more than 50% be used to define intraoperative success.
  • MAIN OUTCOME MEASURE: Correlation of equivocal scan interpretation with operative findings and biochemical cure of hyperparathyroidism.
  • Two failures were associated with a false-positive iPTH level decrease and 2 with failure to find the adenoma.
  • Of the other 22 patients, in addition to the 3 failures, 7 had 4-gland hyperplasia, 4 had double adenomas, and 6 had false-negative iPTH level results with iPTH level decreases of less than 50%.
  • [MeSH-major] Adenoma / surgery. Hyperparathyroidism / surgery. Monitoring, Intraoperative. Parathyroid Hormone / blood. Parathyroid Neoplasms / surgery

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • COS Scholar Universe. author profiles.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16785355.001).
  • [ISSN] 0004-0010
  • [Journal-full-title] Archives of surgery (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Parathyroid Hormone; 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


33. Taïeb D, Hassad R, Sebag F, Colavolpe C, Guedj E, Hindié E, Henry JF, Mundler O: Tomoscintigraphy improves the determination of the embryologic origin of parathyroid adenomas, especially in apparently inferior glands: imaging features and surgical implications. J Nucl Med Technol; 2007 Sep;35(3):135-9
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tomoscintigraphy improves the determination of the embryologic origin of parathyroid adenomas, especially in apparently inferior glands: imaging features and surgical implications.
  • Identification of the embryologic origin of hyperfunctioning parathyroid adenomas in primary hyperparathyroidism (PHPT) could determine the most suitable approach for minimally invasive surgery.
  • The aim of this study was to prospectively evaluate the reliability of a new, combined protocol for the preoperative localization and determination of the embryologic origin of parathyroid adenomas.
  • On the basis of anatomic considerations, adenomas were classified as superior (P4 derived) if they were located above the isthmus or posterior to the thyroid on SPECT images, despite their apparently middle to inferior position, and as inferior (P3 derived) if the foci were located in inferior and anterior positions or along the thyrothymic tract.
  • Parathyroid ultrasonography was performed on all patients.
  • RESULTS: A total of 36 adenomas were removed: 34 solitary adenomas and 1 double adenoma (for totals of 19 P3-derived and 17 P4-derived adenomas).
  • Pinhole subtraction imaging, SPECT, and ultrasonography sensitivities for detecting adenomas were 86%, 78%, and 77%, respectively.
  • Positive SPECT results were associated with higher gland weights.
  • Only 2 corresponded to large P3-derived adenomas (>2 g).
  • CONCLUSION: By reclassifying apparently inferior adenomas as P4-derived adenomas prolapsed behind the thyroid gland, SPECT provides information about the most suitable surgical approach for avoiding recurrent laryngeal nerve injury.
  • Additional pinhole images should increase the detection of small adenomas.
  • [MeSH-major] Adenoma / radiography. Adenoma / surgery. Parathyroid Neoplasms / radiography. Parathyroid Neoplasms / surgery. Parathyroidectomy / methods. Technetium Tc 99m Sestamibi. Tomography, Emission-Computed, Single-Photon / methods

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17702904.001).
  • [ISSN] 0091-4916
  • [Journal-full-title] Journal of nuclear medicine technology
  • [ISO-abbreviation] J Nucl Med Technol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


34. Summers SH, Foo FJ, Varadarajan S: Hypercalcaemia in breast cancer patients: not always bony metastases. BMJ Case Rep; 2009;2009
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Sestamibi scan revealed the cause to be a large parathyroid adenoma which was then removed.
  • Primary hyperparathyroidism is one of the most frequent causes of benign hypercalcaemia, but is often not considered in oncology patients.
  • This case illustrates the importance of considering two primary pathologies.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] N Engl J Med. 2005 Jan 27;352(4):373-9 [15673803.001]
  • [Cites] JAMA. 1995 Aug 2;274(5):402-7 [7616636.001]
  • [Cites] Acta Med Scand. 1986;220(5):455-63 [3812029.001]
  • [Cites] Am J Med. 1976 Jul;61(1):136-9 [937366.001]
  • [Cites] Cancer. 1950 Jan;3(1):74-85 [15405683.001]
  • [Cites] Semin Oncol. 1990 Apr;17(2 Suppl 5):3-9 [2185551.001]
  • [Cites] J Bone Miner Res. 2002 Nov;17 Suppl 2:N18-23 [12412773.001]
  • [Cites] Int J Clin Pract. 2003 Oct;57(8):729-30 [14627187.001]
  • [Cites] Arch Surg. 1981 May;116(5):545-52 [7235946.001]
  • (PMID = 21686968.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3029300
  •  go-up   go-down


35. Ypsilantis E, Charfare H, Wassif WS: Intraoperative PTH Assay during Minimally Invasive Parathyroidectomy May Be Helpful in the Detection of Double Adenomas and May Minimise the Risk of Recurrent Surgery. Int J Endocrinol; 2010;2010:178671
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intraoperative PTH Assay during Minimally Invasive Parathyroidectomy May Be Helpful in the Detection of Double Adenomas and May Minimise the Risk of Recurrent Surgery.
  • Background. Minimally invasive parathyroidectomy (MIP) is increasingly replacing the traditional bilateral neck exploration in the treatment of primary hyperparathyroidism (PHP).
  • Intraoperative PTH (IOPTH) measurement has recently been introduced as a useful adjunct in confirming successful excision of abnormal parathyroid gland. Aims.
  • Results. All patients had successful removal of the abnormal parathyroid gland.
  • The concordance rate between ultrasound and sestamibi scan in localising the parathyroid adenoma was 82%.
  • IOPTH measurement confirmed the removal of adenoma in all cases and, in one case, led to identification of a second adenoma, not localised preoperatively.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Clin Endocrinol (Oxf). 1999 Feb;50(2):191-6 [10396361.001]
  • [Cites] Br J Biomed Sci. 2003;60(1):35-6 [12680632.001]
  • [Cites] Laryngoscope. 2005 Jun;115(6):1128-31 [15933536.001]
  • [Cites] Eur J Nucl Med. 2001 Jun;28(6):736-42 [11440034.001]
  • [Cites] Am J Surg. 2001 Jul;182(1):15-9 [11532408.001]
  • [Cites] Surgery. 2001 Dec;130(6):963-70 [11742324.001]
  • [Cites] J Clin Endocrinol Metab. 2002 Mar;87(3):1024-9 [11889156.001]
  • [Cites] Age Ageing. 2003 Nov;32(6):571-8 [14599996.001]
  • [Cites] Ann R Coll Surg Engl. 1992 Jan;74(1):19-22 [1736788.001]
  • [Cites] Arch Surg. 2002 Aug;137(8):896-9; discussion 899-900 [12146987.001]
  • [Cites] Clin Chem. 2002 Oct;48(10):1731-8 [12324490.001]
  • [Cites] J Am Coll Surg. 2003 Apr;196(4):535-40 [12691927.001]
  • [Cites] BMJ. 2004 Apr 10;328(7444):849-50 [15073054.001]
  • [Cites] Surg Clin North Am. 2004 Jun;84(3):717-34 [15145230.001]
  • [Cites] Arch Surg. 2005 Feb;140(2):146-9; discussion 150 [15723995.001]
  • [Cites] Arch Surg. 2005 Apr;140(4):371-3 [15841560.001]
  • [Cites] Ann Surg. 2005 Sep;242(3):375-80; discussion 380-3 [16135923.001]
  • [Cites] Surgery. 2005 Dec;138(6):1130-5; discussion 1135-6 [16360400.001]
  • [Cites] Surgery. 1997 Mar;121(3):287-94 [9092129.001]
  • [Cites] Am J Surg. 1991 Oct;162(4):299-302 [1683177.001]
  • [Cites] Surgery. 2007 Dec;142(6):930-5; discussion 930-5 [18063078.001]
  • [Cites] World J Surg. 2010 Mar;34(3):538-43 [20052470.001]
  • [Cites] Nucl Med Commun. 1989 Nov;10(11):791-4 [2532313.001]
  • [Cites] Arch Surg. 1989 Mar;124(3):331-5 [2919966.001]
  • [Cites] J Clin Endocrinol Metab. 1993 Dec;77(6):1485-9 [7903311.001]
  • [Cites] Ann Surg. 2009 Mar;249(3):469-72 [19247036.001]
  • [Cites] Br J Surg. 1996 Jul;83(7):989-91 [8813796.001]
  • [Cites] World J Surg. 2002 Aug;26(8):926-30 [11965444.001]
  • [Cites] Ann Surg. 2002 Nov;236(5):543-51 [12409657.001]
  • [Cites] Surg Clin North Am. 2000 Oct;80(5):1399-426 [11059711.001]
  • (PMID = 21197437.001).
  • [ISSN] 1687-8345
  • [Journal-full-title] International journal of endocrinology
  • [ISO-abbreviation] Int J Endocrinol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3010640
  •  go-up   go-down


36. Sendt W, Spieker K, Michael G, Jandt K, Altendorf-Hofmann A: Radio-guided parathyroidectomy in patients with primary hyperparathyroidism and concomitant multinodular goiter. Surg Today; 2010 Sep;40(9):825-30
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radio-guided parathyroidectomy in patients with primary hyperparathyroidism and concomitant multinodular goiter.
  • PURPOSE: We investigated possible instances where the standard bilateral neck exploration for parathyroid adenoma may be omitted in primary hyperparathyroidism (pHPT) if preoperative diagnostics for the location have been performed.
  • Identification of the parathyroid adenomas' location with cervical ultrasound and (99m)technetium-sestamibi nuclear scanning ((99m)Tc-MIBI) was not possible in any of these patients.
  • An extirpation of the parathyroid adenomas was performed with intraoperative use of the (99m)Tc-MIBI-guided probe technique.
  • RESULTS: Ten patients underwent an elective operation for solitary (n = 9) or dual (n = 1) parathyroid adenomas and concomitant thyroid disease.
  • Definitive proof of the parathyroid adenomas was achieved in all of the patients without further neck exploration.
  • The adenomas were 1.3 cm (range 1-2) in diameter.
  • Calcium and parathyroid hormonal levels were reduced on the first postoperative day (P = 0.003).
  • CONCLUSION: The intraoperative probe technique is feasible in patients with pHPT and limited diagnostics for the location of parathyroid adenomas with concomitant goiter.
  • This diagnostic technique identified the parathyroid adenoma in all cases, and thus rendered a bilateral neck exploration obsolete.
  • [MeSH-major] Adenoma / diagnostic imaging. Adenoma / surgery. Goiter, Nodular / surgery. Hyperparathyroidism, Primary / surgery. Parathyroid Neoplasms / diagnostic imaging. Parathyroid Neoplasms / surgery. Parathyroidectomy

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Radiology. 2000 Feb;214(2):393-402 [10671586.001]
  • [Cites] Eur J Nucl Med. 1997 Feb;24(2):143-9 [9021111.001]
  • [Cites] Surg Today. 2008;38(3):222-6 [18306995.001]
  • [Cites] Head Neck. 2002 Jan;24(1):1-5 [11774396.001]
  • [Cites] Ann Surg. 2003 May;237(5):722-30; discussion 730-1 [12724639.001]
  • [Cites] Am Surg. 2006 Sep;72 (9):785-9; discussion 790 [16986387.001]
  • [Cites] World J Surg. 2003 Mar;27(3):339-42 [12607063.001]
  • [Cites] World J Surg. 2002 Jan;26(1):29-34 [11898030.001]
  • [Cites] J Otolaryngol. 1993 Aug;22(4):307-10 [8230383.001]
  • [Cites] World J Surg. 1997 Mar-Apr;21(3):287-90; discussion 290-1 [9015172.001]
  • [Cites] Zentralbl Chir. 1995;120(1):43-6 [7887038.001]
  • [Cites] J Nucl Med. 1997 Jan;38(1):62-5 [8998152.001]
  • [Cites] Nucl Med Commun. 2003 Feb;24(2):121-4 [12548035.001]
  • [Cites] J Am Coll Surg. 2003 Apr;196 (4):541-8 [12691928.001]
  • [Cites] J Nucl Med. 1992 Oct;33(10 ):1801-7 [1328564.001]
  • [Cites] Br J Surg. 2007 Jan;94(1):42-7 [17083106.001]
  • [Cites] J Nucl Med. 2003 Sep;44(9):1443-58 [12960191.001]
  • [Cites] Semin Nucl Med. 2005 Oct;35(4):266-76 [16150247.001]
  • [Cites] World J Surg. 2000 Dec;24(12 ):1573-8 [11193726.001]
  • [Cites] Thyroid. 2002 Jan;12 (1):53-61 [11838731.001]
  • [Cites] J Endocrinol Invest. 2004 Jan;27(1):24-30 [15053239.001]
  • [Cites] J Am Coll Surg. 1998 Mar;186(3):293-305 [9510260.001]
  • [Cites] Surg Oncol Clin N Am. 1999 Jul;8(3):555-64 [10448697.001]
  • [Cites] Nuklearmedizin. 2008;47(1):1-7 [18278205.001]
  • [Cites] Chirurg. 2003 Jun;74(6):593-615; quiz 615-6 [12883812.001]
  • [Cites] Arch Surg. 2000 May;135(5):550-5; discussion 555-7 [10807279.001]
  • [Cites] World J Surg. 1998 Mar;22(3):301-7; discussion 307-8 [9494424.001]
  • [Cites] Arch Surg. 2005 Jul;140(7):656-60 [16027330.001]
  • [Cites] Surgery. 2000 Jul;128(1):29-35 [10876182.001]
  • [Cites] J Nucl Med. 1995 Feb;36(2):241-3 [7830122.001]
  • [Cites] Ann Surg. 2000 Jan;231(1):31-7 [10636099.001]
  • [Cites] Clin Endocrinol (Oxf). 2002 Aug;57(2):241-9 [12153604.001]
  • [Cites] Laryngoscope. 2006 Apr;116(4):580-5 [16585862.001]
  • [Cites] Surgery. 1999 Dec;126(6):1023-8; discussion 1028-9 [10598183.001]
  • [Cites] J Am Coll Surg. 2000 Jul;191(1):24-31 [10898180.001]
  • [Cites] Br J Surg. 2007 Dec;94(12 ):1491-5 [17929232.001]
  • [Cites] Surgery. 2003 Oct;134(4):713-7; discussion 717-9 [14605634.001]
  • [Cites] Chirurg. 1999 Oct;70(10):1102-12 [10550339.001]
  • [Cites] Am J Clin Pathol. 1994 Sep;102(3):365-73 [8085562.001]
  • [Cites] Ann Surg. 1984 Dec;200(6):776-84 [6508409.001]
  • [Cites] Br J Surg. 2006 Apr;93(4):418-21 [16392100.001]
  • [Cites] Ann Surg. 1992 Apr;215(4):300-17 [1558410.001]
  • [Cites] Arch Surg. 2004 Nov;139(11):1175-9 [15545562.001]
  • (PMID = 20740344.001).
  • [ISSN] 1436-2813
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


37. Gates JD, Benavides LC, Shriver CD, Peoples GE, Stojadinovic A: Preoperative thyroid ultrasound in all patients undergoing parathyroidectomy? J Surg Res; 2009 Aug;155(2):254-60
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Coexisting thyroid nodules are the most common cause of false positive localization by radioscintigraphy in the preoperative evaluation for MIPS in patients with primary hyperparathyroidism (pHPT).
  • MATERIALS AND METHODS: Twenty-four patients with biochemically confirmed pHPT were evaluated with thyroid US after localizing (99m)Tc-sestamibi scintigraphy prior to parathyroid operation.
  • RESULTS: Of the 24 patients, 38% (n = 9) had their operations altered from a planned MIPS or four-gland exploration due to coexisting thyroid nodule(s).
  • All but one patient had parathyroid adenoma as the cause of pHPT.
  • CONCLUSION: The routine use of preoperative thyroid US in patients with pHPT undergoing parathyroid surgery may aid in the timely diagnosis and treatment of coexisting thyroid disease.
  • [MeSH-major] Hyperparathyroidism / surgery. Parathyroidectomy. Preoperative Care / methods. Thyroid Gland / ultrasonography

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19482296.001).
  • [ISSN] 1095-8673
  • [Journal-full-title] The Journal of surgical research
  • [ISO-abbreviation] J. Surg. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  •  go-up   go-down


38. Levy MT, Braun JT, Pennant M, Thompson LD: Primary paraganglioma of the parathyroid: a case report and clinicopathologic review. Head Neck Pathol; 2010 Mar;4(1):37-43
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary paraganglioma of the parathyroid: a case report and clinicopathologic review.
  • It is exceedingly uncommon to develop a primary intraparathyroid paraganglioma.
  • Our patient was a 69 year old woman who presented with a thyroid gland mass, with extension into the substernal space.
  • The parathyroid tissue showed a very well defined zellballen arrangement of paraganglion cells within the parenchyma of the parathyroid gland.
  • Isolated paraganglioma within the parathyroid is rare, and should be separated from parathyroid adenoma, hyperplasia or metastatic disease to assure appropriate management.
  • [MeSH-major] Paraganglioma, Extra-Adrenal / pathology. Parathyroid Neoplasms / pathology

  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Thyroid. 2007 Jun;17(6):575-8 [17614779.001]
  • [Cites] Am J Surg Pathol. 2002 May;26(5):551-66 [11979086.001]
  • [Cites] Cancer. 1977 Feb;39(2):397-409 [837327.001]
  • [Cites] Hum Pathol. 1979 Mar;10(2):191-218 [422190.001]
  • [Cites] Clin Nucl Med. 2006 Apr;31(4):234-6 [16550027.001]
  • [Cites] Histopathology. 1993 Jan;22(1):85-7 [8436348.001]
  • [Cites] Ann Vasc Surg. 1994 Nov;8(6):595-8 [7865400.001]
  • [Cites] J Laryngol Otol. 1996 Feb;110(2):196-9 [8729515.001]
  • [Cites] Am J Surg Pathol. 1997 Jul;21(7):748-53 [9236830.001]
  • [Cites] Am Surg. 1987 Jun;53(6):337-8 [2883923.001]
  • (PMID = 20237987.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD56; 0 / Biomarkers, Tumor; 0 / CCND1 protein, human; 0 / Chromogranins; 0 / Synaptophysin; 136601-57-5 / Cyclin D1
  • [Number-of-references] 11
  • [Other-IDs] NLM/ PMC2825535
  •  go-up   go-down


39. Davenport C, Agha A: The role of menin in parathyroid tumorigenesis. Adv Exp Med Biol; 2009;668:79-86
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The role of menin in parathyroid tumorigenesis.
  • Primary hyperparathyroidism is a common disorder that involves the pathological enlargement of one or more parathyroid glands resulting in excessive production of parathyroid hormone (PTH).
  • In vitro experimentation has demonstrated that the presence of menin is required for TGF-beta to effectively inhibit parathyroid cell proliferation and PTH production.
  • This observation correlates with the almost universal occurrence of parathyroid tumors accompanying the inactivation of menin in multiple endocrine neoplasia Type 1 (MEN1) syndrome and the high rate of somatic menin gene mutations seen in sporadic parathyroid adenomas.
  • This chapter aims to review the role of menin in primary hyperparathyroidism and parathyroid hormone-regulation, including the influences of MEN1 gene mutations on parathyroid cell proliferation, differentiation and tumorigenesis.
  • [MeSH-major] Hyperparathyroidism, Primary / metabolism. Parathyroid Neoplasms / metabolism. Proto-Oncogene Proteins / metabolism
  • [MeSH-minor] Humans. Multiple Endocrine Neoplasia Type 1 / genetics. Multiple Endocrine Neoplasia Type 1 / metabolism. Multiple Endocrine Neoplasia Type 1 / physiopathology. Mutation. Parathyroid Glands / metabolism. Parathyroid Glands / pathology. Parathyroid Hormone / metabolism. Signal Transduction / physiology. Smad Proteins / metabolism. Transforming Growth Factor beta / metabolism

  • Genetics Home Reference. consumer health - MEN1 gene.
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20175455.001).
  • [ISSN] 0065-2598
  • [Journal-full-title] Advances in experimental medicine and biology
  • [ISO-abbreviation] Adv. Exp. Med. Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / MEN1 protein, human; 0 / Parathyroid Hormone; 0 / Proto-Oncogene Proteins; 0 / Smad Proteins; 0 / Transforming Growth Factor beta
  • [Number-of-references] 26
  •  go-up   go-down


40. Cayo A, Chen H: Radioguided reoperative parathyroidectomy for persistent primary hyperparathyroidism. Clin Nucl Med; 2008 Oct;33(10):668-70
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radioguided reoperative parathyroidectomy for persistent primary hyperparathyroidism.
  • We report a case of reoperative radioguided parathyroidectomy in a patient with primary hyperparathyroidism.
  • A 58-year-old man presented to our center with persistent hypercalcemia and hyperparathyroidism after 2 previous parathyroid explorations at an outside facility.
  • Despite the use of preoperative and intraoperative localization, identification of the hyperfunctioning gland was unsuccessful during the initial operations.
  • Repeat Tc-99m sestamibi parathyroid scan showed an inferior right parathyroid adenoma.
  • With the intraoperative guidance of a hand-held gamma probe, an enlarged parathyroid gland was localized on the spine behind the esophagus on the right, and successfully removed.
  • Intraoperative parathyroid hormone testing confirmed a surgical cure.
  • The use of radioguidance and intraoperative parathyroid hormone testing were essential to the successful resection.
  • [MeSH-major] Hyperparathyroidism, Primary / radionuclide imaging. Hyperparathyroidism, Primary / surgery. Parathyroidectomy / methods. Surgery, Computer-Assisted / methods. Technetium Tc 99m Sestamibi

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18806564.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


41. Das K, Kendall C, Isabelle M, Fowler C, Christie-Brown J, Stone N: FTIR of touch imprint cytology: a novel tissue diagnostic technique. J Photochem Photobiol B; 2008 Sep 18;92(3):160-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • FTIR spectral profiles of TIC of lymph node and thyroid tissues differ visually when compared with TIC spectra of parathyroid tissue.
  • Parathyroid adenoma showed a marginal shift to lower wavenumbers with decreased amide I and II peak intensities when compared to hyperplasia.
  • Nucleic acid peak positions at 1079cm(-1) and 1244cm(-1) were of higher intensity in adenomas compared to hyperplastic glands possibly demonstrating an increase in cell proliferation and growth.
  • This study demonstrates the feasibility of cytoimprint FTIR for the intraoperative diagnosis of tissue during surgical neck exploration for the management of hyperparathyroidism.
  • There is potential for the application of the technique in sentinel lymph node biopsy diagnosis and tumour margin evaluation.
  • [MeSH-minor] Adenoma / surgery. Esophageal Neoplasms / surgery. Esophagectomy. Frozen Sections. Hyperparathyroidism / surgery. Lymph Node Excision. Parathyroid Neoplasms / surgery. Thyroid Gland / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18640848.001).
  • [ISSN] 1011-1344
  • [Journal-full-title] Journal of photochemistry and photobiology. B, Biology
  • [ISO-abbreviation] J. Photochem. Photobiol. B, Biol.
  • [Language] eng
  • [Grant] United Kingdom / Department of Health / / CSA/03/07/017
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
  •  go-up   go-down


42. Falchetti A, Cilotti A, Vaggelli L, Masi L, Amedei A, Cioppi F, Tonelli F, Brandi ML: A patient with MEN1-associated hyperparathyroidism, responsive to cinacalcet. Nat Clin Pract Endocrinol Metab; 2008 Jun;4(6):351-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A patient with MEN1-associated hyperparathyroidism, responsive to cinacalcet.
  • BACKGROUND: A 30-year-old woman with suspected multiple endocrine neoplasia type 1 (MEN1) was referred to our center in 2001 with primary hyperparathyroidism caused by a multiglandular parathyroid adenoma.
  • The patient underwent a parathyroidectomy with autotransplantation of parathyroid fragments into the nondominant forearm, resulting in resolution of the primary hyperparathyroidism.
  • In 2006 serum calcium and parathyroid hormone (PTH) levels were again found to be high.
  • Ultrasound scan and technetium-99m-labeled hexakis-2-methoxyisobutylisonitrile ((99m)Tc MIBI) scintigraphy evidenced a metabolically active parathyroid nodule in the neck.
  • DIAGNOSIS: Local recurrence of a parathyroid adenoma associated with MEN1.
  • During this time calcium and PTH levels remained normal, morphologically the parathyroid nodular lesion remained unchanged and cinacalcet was well tolerated without the occurrence of adverse events.
  • Cinacalcet could represent an important pharmacological intervention in MEN1-associated primary hyperparathyroidism before surgery and in postsurgical recurrences.
  • [MeSH-major] Hyperparathyroidism, Primary / drug therapy. Multiple Endocrine Neoplasia Type 1 / complications. Naphthalenes / therapeutic use
  • [MeSH-minor] Adult. Calcium / blood. Cinacalcet Hydrochloride. Female. Humans. Parathyroid Hormone / blood

  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [ErratumIn] Nat Clin Pract Endocrinol Metab. 2008 Jul;4(7):420. Vagelli, Luca [corrected to Vaggelli, Luca]
  • (PMID = 18414463.001).
  • [ISSN] 1745-8374
  • [Journal-full-title] Nature clinical practice. Endocrinology & metabolism
  • [ISO-abbreviation] Nat Clin Pract Endocrinol Metab
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Naphthalenes; 0 / Parathyroid Hormone; 1K860WSG25 / Cinacalcet Hydrochloride; SY7Q814VUP / Calcium
  •  go-up   go-down


43. Toi PCh, Varghese RG, Ramdas A, Dasiah SD: Case report of parathyroid carcinoma with raised urinary catecholamines: a diagnostic dilemma. Indian J Pathol Microbiol; 2007 Apr;50(2):389-91
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Case report of parathyroid carcinoma with raised urinary catecholamines: a diagnostic dilemma.
  • Parathyroid carcinoma is often misdiagnosed as thyroid carcinoma clinically and also with fine needle aspiration cytology.
  • Moreover in cases misdiagnosed as thyroid carcinoma pre operatively, raised urinary catecholamines may mislead to a diagnosis of MEN2 A.
  • We report a case of a patient admitted to the surgery department ofour hospital with a swelling in the thyroid region, raised urinary catecholamines and urinary VMA levels, with hypercalciuria and elevated parathyroid hormone levels.
  • It was clinically suspected as thyroid carcinoma with parathyroid adenoma and associated MEN 2A syndrome.
  • [MeSH-major] Catecholamines / urine. Parathyroid Neoplasms / diagnosis. Parathyroid Neoplasms / urine
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged. Multiple Endocrine Neoplasia Type 2a / diagnosis. Thyroid Neoplasms / diagnosis. Vanilmandelic Acid / urine

  • Genetic Alliance. consumer health - Parathyroid carcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17883086.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Catecholamines; 55-10-7 / Vanilmandelic Acid
  •  go-up   go-down


44. Lo CY, Lang BH, Chan WF, Kung AW, Lam KS: A prospective evaluation of preoperative localization by technetium-99m sestamibi scintigraphy and ultrasonography in primary hyperparathyroidism. Am J Surg; 2007 Feb;193(2):155-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A prospective evaluation of preoperative localization by technetium-99m sestamibi scintigraphy and ultrasonography in primary hyperparathyroidism.
  • BACKGROUND: Ultrasonography (USG) and technetium-99m sestamibi (MIBI) scintigraphy are commonly used imaging modalities in the era of minimally invasive parathyroidectomy (MIP) for primary hyperparathyroidism (pHPT).
  • The final pathology included 98 patients with solitary adenoma and 2 patients with multiglandular disease.
  • Correctly localized adenomas were significantly heavier than incorrectly localized ones.
  • Weight of adenoma appeared to be the only clinicopathologic factor determining localization accuracy.
  • [MeSH-major] Adenoma / radionuclide imaging. Adenoma / ultrasonography. Hyperparathyroidism, Primary / etiology. Parathyroid Neoplasms / radionuclide imaging. Technetium Tc 99m Sestamibi
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Female. Humans. Hyperplasia. Male. Middle Aged. Organ Size. Parathyroid Diseases / radionuclide imaging. Parathyroid Diseases / surgery. Parathyroid Diseases / ultrasonography. Parathyroid Glands / pathology. Preoperative Care. Prospective Studies. Sensitivity and Specificity

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17236840.001).
  • [ISSN] 1879-1883
  • [Journal-full-title] American journal of surgery
  • [ISO-abbreviation] Am. J. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


45. Herrmann K, Takei T, Kanegae K, Shiga T, Buck AK, Altomonte J, Schwaiger M, Schuster T, Nishijima K, Kuge Y, Tamaki N: Clinical value and limitations of [11C]-methionine PET for detection and localization of suspected parathyroid adenomas. Mol Imaging Biol; 2009 Sep-Oct;11(5):356-63
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical value and limitations of [11C]-methionine PET for detection and localization of suspected parathyroid adenomas.
  • PURPOSE: The aim of this study was to assess the clinical value of [(11)C]methionine-PET (MET-PET) for detection and localization of parathyroid adenomas in patients without prior thyroidectomy.
  • METHODS: A retrospective analysis of patients with suspected parathyroid adenomas undergoing imaging with MET-PET was performed.
  • Comparison of PET results to other imaging modalities including ultrasound, MIBI scintigraphy, and morphological imaging [computed tomography (CT) and/or magnetic resonance imaging] and subgroup analysis of primary vs. secondary hyperparathyroidism was performed.
  • Validation of PET findings for detection and localization of parathyroid adenomas resulted in an overall sensitivity of MET-PET of 54%, 49%, and 35% on a lesion, side, and location basis, respectively.
  • Subgroup analysis revealed higher sensitivity for MET-PET in secondary HPT (sHPT) than primary HPT (pHPT; 62% vs. 43%; side basis).
  • CONCLUSIONS: In patients with initial diagnosis of hyperparathyroidism and no prior thyroidectomy, the sensitivity of MET-PET for detection and localization of parathyroid adenomas is markedly lower compared to previous reports.
  • The clinical value of MET/PET in patients with hyperparathyroidism should be further investigated in a prospective study utilizing anatometabolic imaging with a PET/CT device.
  • [MeSH-major] Methionine. Parathyroid Neoplasms / diagnostic imaging. Positron-Emission Tomography / methods. Radiopharmaceuticals

  • Hazardous Substances Data Bank. (L)-Methionine .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Ann Surg. 2002 Nov;236(5):543-51 [12409657.001]
  • [Cites] Ann Nucl Med. 2007 Aug;21(6):331-7 [17705012.001]
  • [Cites] Radiology. 2001 Dec;221(3):763-7 [11719674.001]
  • [Cites] Eur J Nucl Med Mol Imaging. 2004 Oct;31(10 ):1405-12 [15278308.001]
  • [Cites] World J Surg. 2001 Jun;25(6):704-7 [11376402.001]
  • [Cites] Nucl Med Commun. 2005 Feb;26(2):133-6 [15657506.001]
  • [Cites] AJR Am J Roentgenol. 2007 Jun;188(6):1706-15 [17515397.001]
  • [Cites] J Nucl Med. 1996 Nov;37(11):1766-70 [8917171.001]
  • [Cites] Eur J Nucl Med. 2001 Feb;28(2):155-64 [11303885.001]
  • [Cites] Ultraschall Med. 2003 Apr;24(2):85-9 [12698372.001]
  • [Cites] Surgery. 1994 Dec;116(6):974-81 [7985105.001]
  • [Cites] World J Surg. 2008 May;32(5):774-81; discussion 782-3 [18335276.001]
  • [Cites] Am J Surg. 1992 Jul;164(1):51-6 [1626607.001]
  • [Cites] Ann Nucl Med. 2004 Sep;18(6):519-26 [15515753.001]
  • [Cites] World J Surg. 2004 Jan;28(1):100-7 [14639488.001]
  • [Cites] Radiology. 2007 Feb;242(2):498-508 [17179397.001]
  • [Cites] Phys Med Biol. 2007 Mar 7;52(5):1505-26 [17301468.001]
  • [Cites] J Nucl Med. 2007 Apr;48(4):501-7 [17401085.001]
  • (PMID = 19340488.001).
  • [ISSN] 1860-2002
  • [Journal-full-title] Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging
  • [ISO-abbreviation] Mol Imaging Biol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 58576-49-1 / carbon-11 methionine; AE28F7PNPL / Methionine
  •  go-up   go-down


46. Torer N, Torun D, Torer N, Micozkadioglu H, Noyan T, Ozdemir FN, Haberal M: Predictors of early postoperative hypocalcemia in hemodialysis patients with secondary hyperparathyroidism. Transplant Proc; 2009 Nov;41(9):3642-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Predictors of early postoperative hypocalcemia in hemodialysis patients with secondary hyperparathyroidism.
  • We sought to investigate predictors of early development of postoperative hypocalcemia in secondary hyperparathyroidism.
  • We recorded preoperative adjusted serum calcium (Ca(+2)), phosphate, alkaline phosphatase, intact parathyroid hormone, and hemoglobin levels; mean systolic and diastolic blood pressure levels; parathyroid ultrasonography and scintigraphic data; and number and weight of the resected adenomas.
  • Age (36.0 +/- 9.7 vs 49.2 +/- 16.6 years; P = .006); levels of preoperative serum Ca(+2) (9.6 +/- 0.7 vs 10.4 +/- 1.1 mg/dL; P = .01), alkaline phosphatase (346.7 +/- 354.7 vs 653.3 +/- 553.7 mg/dL; P = .05), and hemoglobin (10.5 +/- 1.4 vs 12.3 +/- 2.5 g/dL; P = .009); and number (2.0 +/- 1.3 vs 2.9 +/- 0.9; P = .04) and weight (1.9 +/- 2.1 vs 3.2 +/- 1.7; P = .01) of excised parathyroid adenomas were significantly lower among the hypocalcemia than the normocalcemia group.
  • Among hemodialysis patients with secondary hyperparathyroidism, age, levels of preoperative serum Ca(+2) and alkaline phosphatase, and number and weight of adenomas were associated with early development of postoperative hypocalcemia.
  • [MeSH-major] Hyperparathyroidism / physiopathology. Hypocalcemia / etiology. Postoperative Complications / epidemiology. Renal Dialysis. Renal Insufficiency / etiology

  • MedlinePlus Health Information. consumer health - After Surgery.
  • MedlinePlus Health Information. consumer health - Dialysis.
  • Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19917359.001).
  • [ISSN] 1873-2623
  • [Journal-full-title] Transplantation proceedings
  • [ISO-abbreviation] Transplant. Proc.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Hemoglobins; EC 3.1.3.1 / Alkaline Phosphatase; SY7Q814VUP / Calcium
  •  go-up   go-down


47. Muthukrishnan J, Hari Kumar KV, Jha R, Jha S, Modi KD: Distal renal tubular acidosis due to primary hyperparathyroidism. Endocr Pract; 2008 Dec;14(9):1133-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Distal renal tubular acidosis due to primary hyperparathyroidism.
  • OBJECTIVE: To present 4 cases of distal renal tubular acidosis (RTA) in patients with primary hyperparathyroidism (PHPT) and discuss their possible etiopathogenetic correlation.
  • METHODS: We diagnosed distal RTA in 4 patients with symptomatic primary PHPT on the basis of the baseline biochemical variables and the results of the ammonium chloride loading test.
  • Complete resolution of distal RTA was documented after surgical cure of PHPT by removal of a parathyroid adenoma.
  • Inappropriately alkaline fasting urine (pH >5.5) in association with a normal anion gap metabolic acidosis suggested the diagnosis of distal RTA.
  • Cure of distal RTA after surgical treatment of PHPT establishes PHPT as the primary cause of distal RTA in these cases.
  • [MeSH-major] Acidosis, Renal Tubular / etiology. Hyperparathyroidism, Primary / complications
  • [MeSH-minor] Adolescent. Adult. Bone Diseases / diagnosis. Bone Diseases / etiology. Female. Humans. Male. Middle Aged. Muscular Diseases / diagnosis. Muscular Diseases / etiology. Young Adult


48. Sharretts JM, Simonds WF: Clinical and molecular genetics of parathyroid neoplasms. Best Pract Res Clin Endocrinol Metab; 2010 Jun;24(3):491-502
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical and molecular genetics of parathyroid neoplasms.
  • Primary hyperparathyroidism (HPT) results from the excessive secretion of parathyroid hormone from parathyroid tumours.
  • The study of these syndromes has helped define the pathophysiology of both familial and sporadic parathyroid neoplasms.
  • Investigation of kindred with multiple endocrine neoplasia type 1 (MEN1) and the hyperparathyroidism-jaw tumour syndrome (HPT-JT) led to the discovery of the tumour suppressor genes MEN1 and HRPT2.
  • We now recognise that somatic mutations in MEN1 and HRPT2 tumour suppressor genes are frequent events in sporadic parathyroid adenomas and carcinomas, respectively.
  • Parathyroid tumours in the MEN2A syndrome result from mutational activation of the RET oncogene.
  • The CCND1/PRAD1 oncogene was discovered by analysis of sporadic parathyroid tumours.
  • Studies of familial isolated HPT and analysis of chromosomal loss and gain in parathyroid tumours suggest that other genes relevant to parathyroid neoplasia await identification.
  • [MeSH-major] Hyperparathyroidism, Primary / genetics. Parathyroid Neoplasms / genetics
  • [MeSH-minor] Female. Humans. Male. Multiple Endocrine Neoplasia Type 1 / genetics. Multiple Endocrine Neoplasia Type 1 / pathology. Parathyroid Hormone / genetics. Proto-Oncogene Proteins c-ret / genetics. Tumor Suppressor Proteins / genetics

  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Published by Elsevier Ltd.
  • [Cites] Adv Anat Pathol. 2009 Jan;16(1):23-32 [19098464.001]
  • [Cites] J Clin Endocrinol Metab. 2009 May;94(5):1826-34 [19141585.001]
  • [Cites] J Intern Med. 2009 Jul;266(1):84-98 [19522828.001]
  • [Cites] Lancet. 2009 Jul 11;374(9684):145-58 [19595349.001]
  • [Cites] Mol Cell Endocrinol. 2009 Dec 10;313(1-2):1-8 [19729047.001]
  • [Cites] World J Surg. 2009 Nov;33(11):2224-33 [19373510.001]
  • [Cites] J Endocrinol Invest. 2009 Jun;32(6):512-8 [19474519.001]
  • [Cites] Endocr Pract. 2009 Sep-Oct;15(6):567-72 [19491073.001]
  • [Cites] J Clin Endocrinol Metab. 2009 Nov;94(11):4372-9 [19789209.001]
  • [Cites] Endocr Relat Cancer. 2009 Dec;16(4):1313-27 [19620250.001]
  • [Cites] Endocr Relat Cancer. 2010 Mar;17(1):135-46 [19926710.001]
  • [Cites] Eur J Endocrinol. 2000 Jul;143(1):47-54 [10870030.001]
  • [Cites] Am J Pathol. 2000 Aug;157(2):579-86 [10934160.001]
  • [Cites] Hum Mutat. 2000 Oct;16(4):281-96 [11013439.001]
  • [Cites] Cancer Res. 2000 Oct 1;60(19):5553-7 [11034102.001]
  • [Cites] Endocrinol Metab Clin North Am. 2000 Sep;29(3):503-22 [11033758.001]
  • [Cites] N Engl J Med. 2000 Dec 21;343(25):1863-75 [11117980.001]
  • [Cites] Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):1118-23 [11158604.001]
  • [Cites] Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3837-42 [11274402.001]
  • [Cites] Am J Pathol. 2001 Apr;158(4):1355-62 [11290553.001]
  • [Cites] Trends Endocrinol Metab. 2001 May-Jun;12(4):173-8 [11295574.001]
  • [Cites] Cancer Lett. 2002 Jan 25;175(2):175-9 [11741745.001]
  • [Cites] Medicine (Baltimore). 2002 Jan;81(1):1-26 [11807402.001]
  • [Cites] Eur J Endocrinol. 2002 Feb;146(2):209-13 [11834430.001]
  • [Cites] Clin Endocrinol (Oxf). 2002 Apr;56(4):457-64 [11966738.001]
  • [Cites] Endocr Pathol. 2002 Spring;13(1):3-16 [12114746.001]
  • [Cites] Mayo Clin Proc. 2002 Aug;77(8):866-9 [12173721.001]
  • [Cites] Am J Pathol. 2002 Oct;161(4):1299-306 [12368203.001]
  • [Cites] Nat Genet. 2002 Dec;32(4):676-80 [12434154.001]
  • [Cites] J Intern Med. 2003 Jun;253(6):634-42 [12755959.001]
  • [Cites] Cell. 2003 Jun 27;113(7):881-9 [12837246.001]
  • [Cites] J Med Genet. 2003 Sep;40(9):657-63 [12960210.001]
  • [Cites] Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):10770-5 [12960363.001]
  • [Cites] Cancer Res. 2003 Oct 1;63(19):6135-9 [14559791.001]
  • [Cites] N Engl J Med. 2003 Oct 30;349(18):1722-9 [14585940.001]
  • [Cites] Cancer Res. 2003 Nov 15;63(22):8022-8 [14633735.001]
  • [Cites] J Clin Endocrinol Metab. 2004 Jan;89(1):96-102 [14715834.001]
  • [Cites] J Med Genet. 2004 Mar;41(3):155-60 [14985373.001]
  • [Cites] J Med Genet. 2004 Mar;41(3):e32 [14985403.001]
  • [Cites] Mol Cell. 2004 Feb 27;13(4):587-97 [14992727.001]
  • [Cites] Cancer Res. 2004 Mar 15;64(6):2222-8 [15026366.001]
  • [Cites] Mol Cell Biol. 2004 Jul;24(13):5639-49 [15199122.001]
  • [Cites] Cancer Res. 2004 Sep 15;64(18):6791-6 [15374998.001]
  • [Cites] Proc Natl Acad Sci U S A. 1971 Apr;68(4):820-3 [5279523.001]
  • [Cites] Medicine (Baltimore). 1981 Nov;60(6):397-412 [7311809.001]
  • [Cites] Am J Med. 1985 Mar;78(3):467-74 [2858157.001]
  • [Cites] J Clin Invest. 1989 Jun;83(6):2034-40 [2723071.001]
  • [Cites] Surgery. 1990 Dec;108(6):1006-12; discussion 1012-3 [2123361.001]
  • [Cites] Oncogene. 1991 Mar;6(3):449-53 [2011400.001]
  • [Cites] Nature. 1991 Apr 11;350(6318):512-5 [1826542.001]
  • [Cites] Medicine (Baltimore). 1992 Jul;71(4):197-205 [1518393.001]
  • [Cites] Am J Hum Genet. 1993 Jul;53(1):193-200 [8317484.001]
  • [Cites] Cell. 1993 Dec 31;75(7):1297-303 [7916660.001]
  • [Cites] J Clin Endocrinol Metab. 1995 Jan;80(1):254-7 [7829622.001]
  • [Cites] N Engl J Med. 1995 Jul 27;333(4):234-40 [7791841.001]
  • [Cites] Cancer Lett. 1995 Jul 13;93(2):165-70 [7621424.001]
  • [Cites] J Clin Endocrinol Metab. 1995 Nov;80(11):3107-10 [7593409.001]
  • [Cites] J Clin Endocrinol Metab. 1996 May;81(5):1736-9 [8626826.001]
  • [Cites] JAMA. 1996 Nov 20;276(19):1575-9 [8918855.001]
  • [Cites] Science. 1997 Apr 18;276(5311):404-7 [9103196.001]
  • [Cites] Hum Mol Genet. 1997 Jul;6(7):1169-75 [9215689.001]
  • [Cites] J Clin Endocrinol Metab. 1997 Oct;82(10):3481-6 [9329389.001]
  • [Cites] J Clin Endocrinol Metab. 1998 May;83(5):1766-70 [9589690.001]
  • [Cites] J Clin Endocrinol Metab. 1998 Aug;83(8):2627-30 [9709922.001]
  • [Cites] J Clin Endocrinol Metab. 1998 Aug;83(8):2960-3 [9709976.001]
  • [Cites] Cancer Genet Cytogenet. 1998 Oct 1;106(1):30-6 [9772906.001]
  • [Cites] Surgery. 1998 Dec;124(6):993-9 [9854574.001]
  • [Cites] Am J Hum Genet. 1999 Jan;64(1):189-95 [9915958.001]
  • [Cites] Cell. 1999 Jan 8;96(1):143-52 [9989505.001]
  • [Cites] Kidney Int. 1999 Apr;55(4):1375-83 [10201002.001]
  • [Cites] Mod Pathol. 1999 Apr;12(4):412-6 [10229506.001]
  • [Cites] J Bone Miner Res. 1999 Jun;14(6):878-82 [10352095.001]
  • [Cites] J Clin Endocrinol Metab. 1999 Oct;84(10):3775-80 [10523029.001]
  • [Cites] J Clin Endocrinol Metab. 2004 Nov;89(11):5583-91 [15531515.001]
  • [Cites] J Intern Med. 2005 Jan;257(1):18-26 [15606373.001]
  • [Cites] Mol Cell Biol. 2005 Jan;25(2):612-20 [15632063.001]
  • [Cites] Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):749-54 [15640349.001]
  • [Cites] Crit Rev Clin Lab Sci. 2005;42(1):35-70 [15697170.001]
  • [Cites] Adv Anat Pathol. 2005 Mar;12(2):53-61 [15731573.001]
  • [Cites] Otolaryngol Head Neck Surg. 2005 Mar;132(3):359-72 [15746845.001]
  • [Cites] J Endocrinol Invest. 2004 Dec;27(11):1015-21 [15754732.001]
  • [Cites] Nat Rev Cancer. 2005 May;5(5):367-75 [15864278.001]
  • [Cites] J Clin Endocrinol Metab. 2005 Sep;90(9):5015-7 [15956079.001]
  • [Cites] Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14659-64 [16195383.001]
  • [Cites] Clin Endocrinol (Oxf). 2006 Feb;64(2):146-52 [16430712.001]
  • [Cites] Proc Natl Acad Sci U S A. 2006 Jan 24;103(4):1018-23 [16415155.001]
  • [Cites] J Med Genet. 2006 Mar;43(3):e12 [16525030.001]
  • [Cites] Cancer Res. 2006 Sep 1;66(17):8397-403 [16951149.001]
  • [Cites] Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15558-63 [17030811.001]
  • [Cites] J Clin Endocrinol Metab. 2006 Dec;91(12):5019-21 [17003089.001]
  • [Cites] Mol Cancer Res. 2007 Feb;5(2):183-93 [17314275.001]
  • [Cites] Hum Mutat. 2008 Jan;29(1):22-32 [17879353.001]
  • [Cites] Endocr Relat Cancer. 2008 Mar;15(1):267-75 [18310293.001]
  • [Cites] Mol Cell Biol. 2008 May;28(9):2930-40 [18212049.001]
  • [Cites] Genes Chromosomes Cancer. 2008 Aug;47(8):639-48 [18398822.001]
  • [Cites] Cancer Cell. 2008 Jul 8;14(1):36-46 [18598942.001]
  • [Cites] Mol Cancer. 2008;7:65 [18687124.001]
  • [Cites] Proc Natl Acad Sci U S A. 2008 Nov 11;105(45):17420-5 [18987311.001]
  • [Cites] J Bone Miner Res. 2009 Jan;24(1):102-4 [18767934.001]
  • (PMID = 20833339.001).
  • [ISSN] 1878-1594
  • [Journal-full-title] Best practice & research. Clinical endocrinology & metabolism
  • [ISO-abbreviation] Best Pract. Res. Clin. Endocrinol. Metab.
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / / Z01 DK043012-06
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural; Review
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / CDC73 protein, human; 0 / Parathyroid Hormone; 0 / Tumor Suppressor Proteins; EC 2.7.10.1 / Proto-Oncogene Proteins c-ret; EC 2.7.10.1 / RET protein, human
  • [Other-IDs] NLM/ NIHMS172037; NLM/ PMC2939004
  •  go-up   go-down


49. Hultin H, Hellman P, Lundgren E, Olovsson M, Ekbom A, Rastad J, Montgomery SM: Association of parathyroid adenoma and pregnancy with preeclampsia. J Clin Endocrinol Metab; 2009 Sep;94(9):3394-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Association of parathyroid adenoma and pregnancy with preeclampsia.
  • OBJECTIVE: Case reports have described associations between calcium metabolism disturbances and primary hyperparathyroidism with preeclampsia, suggesting parathyroid involvement in preeclampsia etiology.
  • This study examines whether parathyroid adenoma, the main cause of hyperparathyroidism, diagnosed and treated before pregnancy is associated with preeclampsia.
  • DESIGN: We conducted a register-based study to assess the association between parathyroid adenoma and subsequent preeclampsia.
  • POPULATION: The study population included 52 women with a diagnosis of parathyroid adenoma and 519 without, all of whom had a subsequent singleton pregnancy between 1973 and 1997.
  • METHODS: We performed a conditional logistic regression investigating the association of parathyroid adenoma with subsequent preeclampsia in the first singleton pregnancy with adjustment for potential confounding factors.
  • MAIN OUTCOME MEASURE: The main outcome was a diagnosis of preeclampsia that does not include women with prior chronic hypertension.
  • To ensure that treatment of parathyroid adenoma was completed before pregnancy, those with a diagnosis of parathyroid adenoma made less than 2 yr before delivery (and the matched comparison women) were excluded.
  • RESULTS: Statistically, parathyroid adenoma prior to delivery is significantly (P < 0.001) associated with preeclampsia, producing an adjusted odds ratio of 6.89 (95% confidence interval, 2.30, 20.58).
  • CONCLUSION: A history of parathyroid adenoma should be viewed as a risk for preeclampsia.
  • [MeSH-major] Adenoma / complications. Parathyroid Neoplasms / complications. Pre-Eclampsia / etiology. Pregnancy Complications, Neoplastic
  • [MeSH-minor] Adult. Female. Humans. Parathyroid Hormone / blood. Pregnancy

  • Genetic Alliance. consumer health - Preeclampsia.
  • Genetic Alliance. consumer health - Pregnancy.
  • MedlinePlus Health Information. consumer health - Tumors and Pregnancy.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19531594.001).
  • [ISSN] 1945-7197
  • [Journal-full-title] The Journal of clinical endocrinology and metabolism
  • [ISO-abbreviation] J. Clin. Endocrinol. Metab.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Parathyroid Hormone
  •  go-up   go-down


50. Lee LS, Canter RJ, Fraker DL: Intraoperative jugular venous sampling AIDS detection of an undescended parathyroid adenoma. World J Surg; 2006 Apr;30(4):620-3
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intraoperative jugular venous sampling AIDS detection of an undescended parathyroid adenoma.
  • INTRODUCTION: A missed parathyroid adenoma is an important cause of persistent or recurrent primary hyperparathyroidism.
  • Despite the widespread use of preoperative localizing tests and the advent of the rapid intact blood parathyroid hormone assay (iPTH), difficult operative cases are encountered when abnormal parathyroid glands cannot be identified.
  • METHODS: Over a 5-year period, 466 neck explorations were performed for primary hyperparathyroidism.
  • This retrospective report describes the use of intraoperative jugular venous sampling to locate and remove successfully undescended parathyroid adenomas in three patients.
  • RESULTS: Intraoperative jugular venous sampling for iPTH analysis was performed when a thorough neck exploration in combination with peripheral iPTH failed to reveal a source of hyperparathyroidism in patients with biochemically confirmed hyperparathyroidism.
  • In all patients, a two- to fourfold iPTH gradient was observed between the affected and unaffected sides, and an undescended adenoma was located near the carotid bifurcation.
  • CONCLUSIONS: Intraoperative jugular venous sampling with iPTH analysis may be a useful technique for successfully detecting an undescended adenoma when other, more routine measures have failed.
  • [MeSH-major] Adenoma / surgery. Hyperparathyroidism / surgery. Monitoring, Intraoperative / methods. Parathyroid Hormone / blood. Parathyroid Neoplasms / surgery. Parathyroidectomy / methods
  • [MeSH-minor] Humans. Jugular Veins. Parathyroid Glands / abnormalities. Retrospective Studies. Sensitivity and Specificity. Tomography, Emission-Computed, Single-Photon

  • Genetic Alliance. consumer health - AIDS-HIV.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Surgery. 1994 Dec;116(6):982-9; discussion 989-90 [7985106.001]
  • [Cites] Otolaryngol Head Neck Surg. 2005 Mar;132(3):359-72 [15746845.001]
  • [Cites] Ann Surg. 1996 Sep;224(3):308-20; discussion 320-1 [8813259.001]
  • [Cites] Arch Surg. 1997 Sep;132(9):969-74; discussion 974-6 [9301609.001]
  • [Cites] J Nucl Med. 2005 Feb;46(2):248-52 [15695783.001]
  • [Cites] J Am Coll Surg. 1998 Mar;186(3):293-305 [9510260.001]
  • [Cites] World J Surg. 1990 May-Jun;14(3):342-8 [2368436.001]
  • [Cites] Arch Surg. 2003 Nov;138(11):1214-8 [14609869.001]
  • [Cites] Clin Chim Acta. 2000 May;295(1-2):193-8 [10767405.001]
  • [Cites] J Am Coll Surg. 2000 May;190(5):540-5 [10801020.001]
  • (PMID = 16555025.001).
  • [ISSN] 0364-2313
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Parathyroid Hormone
  •  go-up   go-down


51. Graff-Baker A, Roman SA, Boffa D, Aslanian H, Sosa JA: Diagnosis of ectopic middle mediastinal parathyroid adenoma using endoscopic ultrasonography-guided fine-needle aspiration with real-time rapid parathyroid hormone assay. J Am Coll Surg; 2009 Sep;209(3):e1-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diagnosis of ectopic middle mediastinal parathyroid adenoma using endoscopic ultrasonography-guided fine-needle aspiration with real-time rapid parathyroid hormone assay.
  • [MeSH-major] Endosonography. Mediastinal Neoplasms / pathology. Parathyroid Glands / pathology. Parathyroid Neoplasms / pathology
  • [MeSH-minor] Aged. Biopsy, Fine-Needle. Diagnosis, Differential. Female. Humans. Thoracic Surgery, Video-Assisted

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19717031.001).
  • [ISSN] 1879-1190
  • [Journal-full-title] Journal of the American College of Surgeons
  • [ISO-abbreviation] J. Am. Coll. Surg.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


52. Shen HC, Li JY, Lo YK: Lithium intoxication-induced acute parkinsonism complicated with hyperparathyroidism and nephrogenic diabetes insipidus: report of a case. Acta Neurol Taiwan; 2007 Dec;16(4):231-3
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lithium intoxication-induced acute parkinsonism complicated with hyperparathyroidism and nephrogenic diabetes insipidus: report of a case.
  • CASE REPORT: We report a case of a 67-year-old woman with a bipolar affective disorder who was treated with lithium for 10 years.
  • She was found to have a high serum level of intact parathyroid hormone: 135.0 pg/ml and a suspicious parathyroid adenoma.
  • CONCLUSIONS: Tremor is the most frequent movement disorder associated with lithium therapy, while severe parkinsonism has been rarely reported.
  • It should be kept in mind in differential diagnosis of acute parkinsonism especially in elder patients who receive a chronic lithium carbonate therapy.
  • [MeSH-major] Diabetes Insipidus, Nephrogenic / chemically induced. Hyperparathyroidism / chemically induced. Lithium Carbonate / poisoning. Parkinsonian Disorders / chemically induced


53. Salman M P, González V G, Grant del R C, González D H, Arteaga U E: [Primary hyperparathyroidism in an adolescent. Report of one case]. Rev Med Chil; 2008 Oct;136(10):1301-6
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary hyperparathyroidism in an adolescent. Report of one case].
  • Bone densitometry showed spine and femur Z scores of -2.9 and -1.6, respectively, kidney ultrasound showed nephrocalcinosis and a MIBI-SPECT scintigram showed a higher uptake in the right lower parathyroid gland.
  • The diagnosis of primary hyperparathyroidism was made and the patient was operated, excising the right lower parathyroid gland.
  • In children, the proportion of cases with parathyroid hyperplasia is higher than in adults.
  • Therefore, during surgery all four parathyroid glands must be explored.
  • There is also a higher frequency of ectopic adenomas.
  • Family history must be explored to discard the presence of a multiple endocrine neoplasia (MEN I or II), a familial hyperparathyroidism or a syndrome of primary hyperparathyroidism associated to mandibular tumor.
  • [MeSH-major] Hyperparathyroidism, Primary / diagnosis
  • [MeSH-minor] Adolescent. Densitometry. Humans. Hyperplasia. Male. Parathyroid Glands / pathology. Parathyroid Glands / radionuclide imaging. Parathyroid Glands / surgery. Tomography, Emission-Computed, Single-Photon

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19194627.001).
  • [ISSN] 0034-9887
  • [Journal-full-title] Revista médica de Chile
  • [ISO-abbreviation] Rev Med Chil
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Chile
  •  go-up   go-down


54. Elisei R, Romei C, Cosci B, Agate L, Bottici V, Molinaro E, Sculli M, Miccoli P, Basolo F, Grasso L, Pacini F, Pinchera A: RET genetic screening in patients with medullary thyroid cancer and their relatives: experience with 807 individuals at one center. J Clin Endocrinol Metab; 2007 Dec;92(12):4725-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Three different syndromes are distinguished: MEN 2A, when medullary thyroid carcinoma (MTC) is associated with pheochromocytoma and/or parathyroid adenomas; MEN 2B, when accompanied by a marfanoid habitus and/or pheochromocytoma; and familial medullary thyroid carcinoma (FMTC), when only MTC is present.


55. Yener S, Saklamaz A, Demir T, Kebapcilar L, Bayraktar F, Canda S, Yesil S: Primary hyperparathyroidism due to atypical parathyroid adenoma presenting with peroneus brevis tendon rupture. J Endocrinol Invest; 2007 May;30(5):442-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary hyperparathyroidism due to atypical parathyroid adenoma presenting with peroneus brevis tendon rupture.
  • [MeSH-major] Adenoma / complications. Hyperparathyroidism, Primary / etiology. Parathyroid Neoplasms / complications. Tendon Injuries / etiology

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Br Heart J. 1985 Nov;54(5):539-42 [2932135.001]
  • [Cites] Am J Med. 1993 Aug;95(2):197-202 [8356983.001]
  • [Cites] JAMA. 1972 Jul 24;221(4):406-7 [5067852.001]
  • [Cites] J Bone Miner Res. 1991 Oct;6 Suppl 2:S85-9; discussion S121-4 [1662460.001]
  • [Cites] Orthopedics. 1999 Dec;22(12):1177-9 [10604812.001]
  • [Cites] Ann Intern Med. 1974 Feb;80(2):182-93 [4811792.001]
  • [Cites] Ann Emerg Med. 1989 Jul;18(7):783-4 [2735601.001]
  • [Cites] J Foot Ankle Surg. 1999 Sep-Oct;38(5):359-62 [10553550.001]
  • [Cites] Rev Fac Cien Med Univ Nac Cordoba. 2004;61(1):37-9 [15366234.001]
  • [Cites] Hum Pathol. 2003 Jan;34(1):54-64 [12605367.001]
  • [Cites] World J Surg. 2000 Jan;24(1):102-7 [10594212.001]
  • [Cites] J Bone Miner Res. 1989 Jun;4(3):283-91 [2763869.001]
  • [Cites] Br J Radiol. 1983 Dec;56(672):915-20 [6652412.001]
  • (PMID = 17598980.001).
  • [ISSN] 1720-8386
  • [Journal-full-title] Journal of endocrinological investigation
  • [ISO-abbreviation] J. Endocrinol. Invest.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Italy
  •  go-up   go-down


56. Erbil Y, Barbaros U, Tükenmez M, Işsever H, Salmaslioğlu A, Adalet I, Ozarmağan S, Tezelman S: Impact of adenoma weight and ectopic location of parathyroid adenoma on localization study results. World J Surg; 2008 Apr;32(4):566-71
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Impact of adenoma weight and ectopic location of parathyroid adenoma on localization study results.
  • Although the sensitivity of preoperative localization techniques is high for solitary parathyroid adenomas, negative imaging study results are inevitable.
  • The weight and location of the parathyroid adenoma may contribute to the negative results.
  • We aimed to study the impact of adenoma weight and ectopic location of the parathyroid adenoma on ultrasonography and sestamibi scan results.
  • The patients were divided into two groups according to adenoma location.
  • Parathyroid adenoma weight and the results of imaging studies were determined in all patients.
  • Of 185 patients operated on for hyperparathyroidism, 36 (19.4%) had ectopic parathyroid glands.
  • There was a positive correlation between adenoma weight and positive imaging studies, whereas ectopic location did not correlate with negative imaging study results.
  • There was no significant difference between the ectopic adenoma ratio of patients with negative and positive imaging study results.
  • The weight of the ectopic parathyroid adenoma was significantly lower in patients with negative imaging study results than in patients with positive imaging study results (p = 0.001).
  • According to the analysis of variance, patients with higher-weight adenomas have positive imaging study results irrespective of ectopic location.
  • For both normal and ectopic adenoma locations, adenoma weight was found only to be a factor that positively influences imaging study results.
  • [MeSH-major] Adenoma / pathology. Choristoma / pathology. Parathyroid Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Analysis of Variance. Calcium / blood. Female. Follow-Up Studies. Humans. Male. Middle Aged. Organ Size. Parathyroid Hormone / blood. Radionuclide Imaging. Retrospective Studies. Ultrasonography

  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Surgery. 1999 Dec;126(6):1123-31 [10598197.001]
  • [Cites] J Clin Ultrasound. 2007 Mar-Apr;35(3):144-55 [17295270.001]
  • [Cites] Clin Nucl Med. 2001 Feb;26(2):139-44 [11201472.001]
  • [Cites] Am J Surg. 2006 Mar;191(3):418-23 [16490559.001]
  • [Cites] Rev Endocr Metab Disord. 2000 Nov;1(4):237-45 [11706737.001]
  • [Cites] Surgery. 2001 Dec;130(6):1039-43 [11742335.001]
  • [Cites] Laryngoscope. 2003 Mar;113(3):567-72 [12616216.001]
  • [Cites] J Nucl Med. 2003 Sep;44(9):1443-58 [12960191.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 2005 Jun;131(6):493-8 [15967881.001]
  • [Cites] Surgery. 2004 Oct;136(4):872-80 [15467674.001]
  • [Cites] Arch Surg. 2007 Apr;142(4):381-6 [17441292.001]
  • [Cites] Trends Endocrinol Metab. 2003 Nov;14 (9):417-22 [14580761.001]
  • [Cites] Arch Surg. 2002 Sep;137(9):1055-9 [12215160.001]
  • [Cites] Mo Med. 1967 Mar;64(3):234-8 [6041537.001]
  • [Cites] J Bone Miner Res. 2002 Nov;17 Suppl 2:N12-7 [12412772.001]
  • [Cites] Am J Surg. 2007 Feb;193(2):155-9 [17236840.001]
  • [Cites] Radiographics. 2004 Jul-Aug;24(4):1101-15 [15256632.001]
  • [Cites] Clin Endocrinol (Oxf). 2002 Aug;57(2):241-9 [12153604.001]
  • [Cites] World J Surg. 2000 Feb;24(2):158-65 [10633142.001]
  • [Cites] Endocr Relat Cancer. 1999 Mar;6(1):123-5 [10732795.001]
  • [Cites] Best Pract Res Clin Endocrinol Metab. 2001 Jun;15(2):139-47 [11472030.001]
  • [Cites] Ultrasound Q. 2006 Dec;22(4):253-62 [17146333.001]
  • [Cites] Ann Surg. 1976 Mar;183(3):271-5 [1259483.001]
  • [Cites] World J Surg. 2006 May;30(5):697-704 [16680585.001]
  • [Cites] Clin Endocrinol (Oxf). 2006 Sep;65(3):340-5 [16918953.001]
  • (PMID = 18210183.001).
  • [ISSN] 0364-2313
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Parathyroid Hormone; SY7Q814VUP / Calcium
  •  go-up   go-down


57. Almquist M, Bergenfelz A, Mårtensson H, Thier M, Nordenström E: Changing biochemical presentation of primary hyperparathyroidism. Langenbecks Arch Surg; 2010 Sep;395(7):925-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Changing biochemical presentation of primary hyperparathyroidism.
  • PURPOSE: Patients with primary hyperparathyroidism, pHPT, present with milder symptoms than previously.
  • Some, but not all studies, suggest that this change in clinical pattern also implies lower preoperative parathyroid hormone (PTH) and/or calcium levels and smaller adenomas.
  • This is important since reports indicate that smaller adenomas are more difficult to detect on preoperative imaging, possibly increasing the risk of surgical failure.
  • METHODS: There were 640 patients with histologically confirmed single-gland pHPT identified in a prospectively collected database.
  • Median values of preoperative calcium, PTH, as well as adenoma weight were compared in three different time periods: 1990-1995, 1996-2000, and 2000-2007.
  • Correlation between the preoperative levels of calcium and PTH and adenoma weight was calculated.
  • There was a positive correlation between preoperative PTH and adenoma weight (r = 0.32, p < 0.001).
  • In women, adenoma weight decreased significantly over time (p = 0.03).
  • Median (25th-75th percentile) adenoma weight in women was 750 (400-1,380) mg, 650 (350-1,205) mg, and 520 (305-1,065) mg in the first, second, and third period, respectively.
  • In women, the adenoma weight decreased.
  • [MeSH-major] Calcium / blood. Hyperparathyroidism, Primary / pathology. Hyperparathyroidism, Primary / surgery. Parathyroid Hormone / blood. Parathyroid Neoplasms / pathology

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Chronic Dis. 1987;40(2):121-30 [3818865.001]
  • [Cites] J Intern Med. 1998 Jun;243(6):581-7 [9681862.001]
  • [Cites] Langenbecks Arch Surg. 2009 Sep;394(5):785-98 [19554347.001]
  • [Cites] Langenbecks Arch Surg. 2009 Sep;394(5):851-60 [19618204.001]
  • [Cites] J Am Coll Surg. 2002 Feb;194(2):126-30 [11848628.001]
  • [Cites] J Clin Endocrinol Metab. 2002 Dec;87(12):5353-61 [12466320.001]
  • [Cites] J Clin Endocrinol Metab. 2003 Jul;88(7):3015-8 [12843136.001]
  • [Cites] Langenbecks Arch Surg. 2009 Sep;394(5):765-84 [19590890.001]
  • [Cites] J Clin Endocrinol Metab. 2008 Sep;93(9):3462-70 [18544625.001]
  • [Cites] Eur J Endocrinol. 2006 Aug;155(2):237-44 [16868136.001]
  • [Cites] Surgery. 1995 Feb;117(2):134-9 [7846616.001]
  • [Cites] Eur J Surg. 1994 Sep;160(9):485-9 [7849167.001]
  • [Cites] Arch Surg. 2004 Jan;139(1):77-82; discussion 82 [14718281.001]
  • [Cites] Surgery. 2006 Apr;139(4):527-34 [16627063.001]
  • [Cites] Arch Surg. 2008 Mar;143(3):260-6 [18347273.001]
  • [Cites] Lancet. 1980 Jun 21;1(8182):1317-20 [6104128.001]
  • (PMID = 20623136.001).
  • [ISSN] 1435-2451
  • [Journal-full-title] Langenbeck's archives of surgery
  • [ISO-abbreviation] Langenbecks Arch Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Parathyroid Hormone; SY7Q814VUP / Calcium
  •  go-up   go-down


58. Enomoto K, Sakurai K, Amano S: [Experience of parathyroid cancer which required a differentiation from adenoma]. Gan To Kagaku Ryoho; 2010 Nov;37(12):2325-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Experience of parathyroid cancer which required a differentiation from adenoma].
  • We noted a thyroid gland mass by examination and referred for a further checkup.
  • The cervical echography evidence showed a mass image of the border regular in the back of inferior pole of left thyroid gland.
  • It also revealed a mass image with the calcification in the inferior pole of left lobe of thyroid gland at the same time.
  • We performed aspiration biopsy cytology for a thyroid gland mass, and it was class IIIa.
  • We also performed parathyroidectomy and left lobe of thyroid gland ablative surgery because of a diagnosis of the hyperparathyroidism confirmed a primary parathyroid adenoma.
  • Preoperative pathological diagnosis was adenoma.
  • However, histopathology laboratory findings showed it to be of adenocarcinoma of the parathyroid, which metastasized into the thyroid.
  • Many times parathyroid cancer preoperative diagnosis is inconclusive.
  • So we are reporting our experience with parathyroid cancer metastases to the thyroid for reference.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenoma / diagnosis. Parathyroid Neoplasms / diagnosis
  • [MeSH-minor] Aged. Diagnosis, Differential. Humans. Hyperparathyroidism / etiology. Hyperparathyroidism / surgery. Male. Parathyroidectomy. Thyroid Neoplasms / secondary. Thyroidectomy

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21224561.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


59. Aloumanis KP, Papapetrou PD: Corpus callosum aplasia in a young patient with a parathyroid adenoma. J Clin Neurosci; 2007 Nov;14(11):1124-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Corpus callosum aplasia in a young patient with a parathyroid adenoma.
  • A young man with primary hyperparathyroidism due to a parathyroid adenoma and aplasia of the corpus callosum is presented.
  • We hypothesize a possible genetic association of the two pathologies: a proportion of the sporadic parathyroid adenomas are associated with genetic abnormalities of chromosome 11 and in some cases of corpus callosum aplasia, aneuploidy or polyploidy of this chromosome has been described.
  • [MeSH-major] Adenoma / complications. Agenesis of Corpus Callosum. Brain Diseases / complications. Hyperparathyroidism, Primary / complications. Parathyroid Neoplasms / complications

  • MedlinePlus Health Information. consumer health - Brain Diseases.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17954377.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
  •  go-up   go-down


60. Hussain R, Zaman MU, Ahmed MN: LOCALIZATION OF A PARATHYROID ADENOMA IN A MULTI-NODULAR GOITER USING SESTAMIBI AND Tc-99m PERTECHNETATE SCANS. J Coll Physicians Surg Pak; 2007 Nov;17(11):712-3
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] LOCALIZATION OF A PARATHYROID ADENOMA IN A MULTI-NODULAR GOITER USING SESTAMIBI AND Tc-99m PERTECHNETATE SCANS.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18070589.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Pakistan
  •  go-up   go-down


61. Deng XL, Liu XY, Xu N: Comparative study on low back pain misdiagnosed as spondyloarthropathy. Clin Rheumatol; 2009 Aug;28(8):893-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This study aims to investigate features of different diseases with low back pain misdiagnosed as spondyloarthropathy so as to improve the accuracy of diagnosis for spondyloarthropathy.
  • The final diagnoses of these 24 cases were listed below: four malignant tumors (retroperitoneal adipose sarcoma, advanced gastric carcinoma, ovarian papillary epithelioma, acute lymphocytic leukemia), six benign tumors (two parathyroid adenoma with hyperparathyroidism, one intraspinal lipoma, intraspinal ependymomas, sacral tubulocyst, and intraspinal schwannoglioma, respectively).
  • [MeSH-major] Diagnostic Errors. Low Back Pain / etiology. Neoplasms / diagnosis. Severity of Illness Index. Spondylarthropathies / complications. Spondylarthropathies / diagnosis
  • [MeSH-minor] Adolescent. Adult. Diagnosis, Differential. Female. HLA-B27 Antigen / analysis. Humans. Male. Medical Audit. Middle Aged. Pain, Referred / etiology. Young Adult

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Bone Joint Surg Am. 2000 Jan;82(1):4-15 [10653079.001]
  • [Cites] Ann Rheum Dis. 2004 May;63(5):535-43 [15082484.001]
  • [Cites] Arthritis Rheum. 1991 Oct;34(10):1218-27 [1930310.001]
  • [Cites] Cancer. 1995 Jun 15;75(12):2954-8 [7773947.001]
  • [Cites] Joint Bone Spine. 2000;67(6):502-3 [11195311.001]
  • [Cites] Lancet. 1999 Aug 14;354(9178):581-5 [10470716.001]
  • [Cites] Arthritis Rheum. 2005 Apr;52(4):1000-8 [15818678.001]
  • [Cites] J Gen Intern Med. 1986 Sep-Oct;1(5):328-38 [2945917.001]
  • [Cites] Proc Soc Exp Biol Med. 2000 Jan;223(1):39-46 [10632959.001]
  • [Cites] Rev Rhum Mal Osteoartic. 1990 Feb;57(2):85-9 [2181618.001]
  • [Cites] Joint Bone Spine. 2000;67(6):516-20 [11195314.001]
  • [Cites] Ann Rheum Dis. 2005 May;64(5):659-63 [15528281.001]
  • [Cites] N Engl J Med. 2001 Feb 1;344(5):363-70 [11172169.001]
  • [Cites] Med Clin North Am. 1986 Mar;70(2):323-36 [3485229.001]
  • (PMID = 19449145.001).
  • [ISSN] 1434-9949
  • [Journal-full-title] Clinical rheumatology
  • [ISO-abbreviation] Clin. Rheumatol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / HLA-B27 Antigen
  •  go-up   go-down


62. Kandil E, Tsai HL, Somervell H, Dackiw AP, Tufano RP, Tufaro AP, Kowalski J, Zeiger MA: African Americans present with more severe primary hyperparathyroidism than non-African Americans. Surgery; 2008 Dec;144(6):1023-6; discussion 1026-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] African Americans present with more severe primary hyperparathyroidism than non-African Americans.
  • BACKGROUND: Similar to other disease states, we postulated that African American patients present with more severe signs of primary hyperparathyroidism than non-African Americans.
  • To test this hypothesis, we compared relevant preoperative laboratory values, sestamibi scan results, and intraoperative findings between African American and non-African American patients with primary hyperparathyroidism who underwent parathyroidectomy between January 2002 and May 2007.
  • A linear model was used to examine the effect of race with respect to mean differences in serum calcium, 25-hydroxyvitamin D (25(OH)D), intact parathyroid hormone (iPTH), alkaline phosphatase (ALKP) levels, gland weight, presence of double adenomas and, sestamibi scan sensitivity.
  • They exhibited significantly lower median serum 25(OH)D (14 [SD = 9.36] vs 23 [SD = 12.160] ng/mL, P < .001), greater gland weight (P < .001), a higher probability of double adenomas (odds ratio = 2.83, 95% confidence interval [CI], 1.36-5.88), and a higher probability of presenting with a positive sestamibi scan (odds ratio = 4.99, 95% CI = 2.44-10.19) compared with non-African Americans.
  • CONCLUSION: African Americans present with more advanced signs of primary hyperparathyroidism than non-African Americans.
  • [MeSH-major] African Americans. Hyperparathyroidism, Primary / diagnosis. Hyperparathyroidism, Primary / ethnology


63. Jackson MB, Guttenberg M, Hedrick H, Moshang T Jr: Multiple endocrine neoplasia type 2A in a kindred with C634Y mutation. Pediatrics; 2005 Sep;116(3):e468-71
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Medullary thyroid carcinoma has occurred before the age of 2, with pheochromocytomas and primary hyperparathyroidism occurring later in childhood.
  • We report cases of 4 siblings with C634Y-positive MEN 2A (all <11 years old): 3 with medullary thyroid carcinoma (1 had nodal metastasis, and another had a parathyroid adenoma) and 1 with C-cell hyperplasia.

  • Genetic Alliance. consumer health - Multiple Endocrine Neoplasia.
  • Genetic Alliance. consumer health - Multiple endocrine neoplasia type 2A.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16099853.001).
  • [ISSN] 1098-4275
  • [Journal-full-title] Pediatrics
  • [ISO-abbreviation] Pediatrics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Codon; EC 2.7.10.1 / Proto-Oncogene Proteins c-ret
  •  go-up   go-down


64. Silberfein EJ, Bao R, Lopez A, Grubbs EG, Lee JE, Evans DB, Perrier ND: Reoperative parathyroidectomy: location of missed glands based on a contemporary nomenclature system. Arch Surg; 2010 Nov;145(11):1065-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVES: To evaluate and categorize the locations of missed parathyroid glands found during reoperative parathyroidectomy and to determine any factors associated with these locations.
  • PATIENTS: Fifty-four patients who underwent reoperative parathyroidectomy for persistent or recurrent hyperparathyroidism from January 1, 2005, through January 1, 2009.
  • MAIN OUTCOME MEASURES: Location of missed parathyroid glands and their association with continuous variables were analyzed using a Kruskal-Wallis test, and associations between gland location and categorical variables were evaluated using the Fisher exact test.
  • RESULTS: Among 54 patients, 50 abnormal parathyroid glands were identified, resected, and classified as follows: 5 (10%) were type A (adherent to the posterior thyroid capsule); 11 (22%), type B (behind the thyroid in the tracheoesophageal groove); 7 (14%), type C (close to the clavicle in the prevertebral space); 3 (6%), type D (directly over the recurrent laryngeal nerve); 9 (18%), type E (easy to identify; near the inferior thyroid pole); 13 (26%), type F (fallen into the thymus); and 2 (4%), type G (gauche, within the thyroid gland).
  • No demographic, biochemical, or pathological factors were significantly associated with gland location.
  • CONCLUSIONS: Missed glands after parathyroidectomy for hyperparathyroidism can be found in standard locations in most cases.
  • A standardized nomenclature system based on the regional anatomy and the embryology of the parathyroid glands can guide a systematic exploration for parathyroid adenomas that are not easily identified and facilitate communication about gland locations.
  • [MeSH-major] Hyperparathyroidism / surgery. Parathyroidectomy
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Parathyroid Glands / pathology. Parathyroid Glands / surgery. Recurrence. Reoperation. Retrospective Studies. Statistics, Nonparametric. Terminology as Topic. Treatment Outcome

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21079094.001).
  • [ISSN] 1538-3644
  • [Journal-full-title] Archives of surgery (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch Surg
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA016672
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


65. Hussein WI, El-Maghraby TA, Al-Sanea O: Hyperfunctioning intrathyroidal parathyroid carcinoma. Saudi Med J; 2006 Aug;27(8):1226-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hyperfunctioning intrathyroidal parathyroid carcinoma.
  • Intrathyroidal parathyroid carcinoma is an exceedingly rare cause of primary hyperparathyroidism with difficulties in the diagnosis and management.
  • We report a case of hypercalcemia from intrathyroidal parathyroid carcinoma in a 63-year-old Saudi female.
  • She was diagnosed 2 years earlier with osteoporosis in a primary care clinic and was on alendronate since then.
  • Parathyroid 99mTc-SestaMIBI scintigraphy revealed parathyroid adenoma in the left inferior parathyroid gland.
  • [MeSH-major] Carcinoma / diagnosis. Hypercalcemia / diagnosis. Hypercalcemia / etiology. Parathyroid Neoplasms / diagnosis
  • [MeSH-minor] Female. Humans. Hyperparathyroidism / complications. Middle Aged. Radiopharmaceuticals. Technetium Tc 99m Sestamibi. Thyroidectomy. Treatment Outcome

  • Genetic Alliance. consumer health - Parathyroid carcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16883457.001).
  • [ISSN] 0379-5284
  • [Journal-full-title] Saudi medical journal
  • [ISO-abbreviation] Saudi Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Saudi Arabia
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


66. McMullen TP, Learoyd DL, Williams DC, Sywak MS, Sidhu SB, Delbridge LW: Hyperparathyroidism in pregnancy: options for localization and surgical therapy. World J Surg; 2010 Aug;34(8):1811-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hyperparathyroidism in pregnancy: options for localization and surgical therapy.
  • BACKGROUND: Hyperparathyroidism in pregnancy is a threat to the health of both mother and fetus.
  • METHODS: This is a case series comprising seven patients with primary hyperparathyroidism in pregnancy.
  • Data collected included symptoms at diagnosis, biochemical abnormalities, pathologic findings, treatment regimes, and subsequent maternal and fetal outcomes.
  • RESULTS: Seven women, aged 20 to 39 years, presented with hyperparathyroidism during pregnancy.
  • All were found to have solitary parathyroid adenomas, of which two were in ectopic locations.
  • Three patients were treated during pregnancy with surgery, and two of these had ectopic glands that required reoperations with a novel approach using Tc-99m sestamibi scanning during pregnancy to assist in localizing the abnormal gland.
  • CONCLUSIONS: Primary hyperparathyroidism in pregnancy represents a significant risk for maternal and fetal complications that cannot be predicted by duration of symptoms or serum calcium levels.
  • [MeSH-major] Hyperparathyroidism / diagnostic imaging. Hyperparathyroidism / surgery. Parathyroid Neoplasms / diagnostic imaging. Parathyroid Neoplasms / surgery. Pregnancy Complications / diagnostic imaging. Pregnancy Complications / surgery

  • Genetic Alliance. consumer health - Pregnancy.
  • MedlinePlus Health Information. consumer health - Health Problems in Pregnancy.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Am J Obstet Gynecol. 1989 Nov;161(5):1178-85 [2589435.001]
  • [Cites] Surg Today. 2008;38(3):222-6 [18306995.001]
  • [Cites] ANZ J Surg. 2006 Dec;76(12 ):1048-50 [17199687.001]
  • [Cites] Am J Surg. 2005 Sep;190(3):467-73 [16105538.001]
  • [Cites] Surgeon. 2007 Oct;5(5):301-8 [17958230.001]
  • [Cites] J Am Soc Nephrol. 2001 Feb;12 Suppl 17:S3-9 [11251025.001]
  • [Cites] Z Geburtshilfe Perinatol. 1994 May-Jun;198(3):96-9 [7941630.001]
  • [Cites] J Gen Intern Med. 1992 Jul-Aug;7(4):448-53 [1506954.001]
  • [Cites] N Engl J Med. 1962 Sep 27;267:637-42 [14467191.001]
  • [Cites] Health Phys. 1997 Nov;73(5):756-69 [9378651.001]
  • [Cites] Surgery. 1991 Dec;110(6):1028-33; discussion 1033-4 [1745971.001]
  • [Cites] Br J Surg. 1984 Mar;71(3):217-8 [6697128.001]
  • [Cites] Am J Surg. 2006 Mar;191(3):418-23 [16490559.001]
  • [Cites] Arch Gynecol Obstet. 1998;261(4):209-14 [9789652.001]
  • [Cites] Dig Surg. 2001;18(5):409-17 [11721118.001]
  • [Cites] Am J Surg. 1999 Jan;177(1):66-8 [10037311.001]
  • [Cites] Acta Endocrinol (Copenh). 1964 Dec;47:549-64 [14250391.001]
  • [Cites] J Reprod Med. 1998 May;43(5):451-4 [9610470.001]
  • [Cites] Br J Surg. 1989 Nov;76(11):1207-8 [2597981.001]
  • [Cites] Am J Med Sci. 2000 Mar;319(3):191-4 [10746832.001]
  • [Cites] Surg Endosc. 2008 Sep;22(9):1917-27 [18553201.001]
  • [Cites] Surgery. 1985 Mar;97(3):326-30 [3975852.001]
  • [Cites] J Obstet Gynaecol. 2004 Apr;24(3):318-9 [15203643.001]
  • [Cites] Endocr Pract. 1999 Nov-Dec;5(6):337-42 [15251655.001]
  • [Cites] Br J Surg. 1998 Dec;85(12 ):1605-16 [9876061.001]
  • [Cites] Clin Endocrinol (Oxf). 1996 Jul;45(1):1-6 [8796131.001]
  • [Cites] J Med Soc N J. 1981 Feb;78(2):113-5 [6938711.001]
  • [Cites] Arch Surg. 2006 Aug;141(8):777-82; discussion 782 [16924085.001]
  • [Cites] Postgrad Med J. 1998 Apr;74(870):233-4 [9683978.001]
  • [Cites] Langenbecks Arch Surg. 2009 Sep;394(5):765-84 [19590890.001]
  • [Cites] Anesthesiology. 1986 Jun;64(6):790-4 [3717642.001]
  • [Cites] Br J Surg. 1979 Sep;66(9):648-50 [497655.001]
  • [Cites] Obstet Gynecol Surv. 2002 Jun;57(6):365-76 [12140371.001]
  • [Cites] Am J Surg. 1976 Mar;131(3):328-37 [769583.001]
  • [Cites] Ann Surg. 1981 Jun;193(6):805-9 [7247524.001]
  • [Cites] Obstet Gynecol Surv. 2005 Oct;60(10):672-82 [16186784.001]
  • [Cites] J Matern Fetal Neonatal Med. 2002 Nov;12(5):349-52 [12607769.001]
  • [Cites] Am J Obstet Gynecol. 1981 Aug 1;140(7):840-2 [7258268.001]
  • [Cites] Gynecol Endocrinol. 2004 Aug;19(2):111-4 [15624273.001]
  • [Cites] J Pediatr Endocrinol Metab. 2001 Jun;14(6):785-7 [11453530.001]
  • [Cites] Obstet Gynecol. 1980 Apr;55(4):431-4 [7366898.001]
  • [Cites] Eur J Nucl Med. 1998 Feb;25(2):193-9 [9473270.001]
  • [Cites] Acta Obstet Gynecol Scand. 1993 Aug;72(6):488-92 [8394630.001]
  • (PMID = 20386905.001).
  • [ISSN] 1432-2323
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


67. Kinoshita Y, Taguchi M, Takeshita A, Miura D, Tomikawa S, Takeuchi Y: 1,25-dihydroxyvitamin D suppresses circulating levels of parathyroid hormone in a patient with primary hyperparathyroidism and coexistent sarcoidosis. J Clin Endocrinol Metab; 2005 Dec;90(12):6727-31
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] 1,25-dihydroxyvitamin D suppresses circulating levels of parathyroid hormone in a patient with primary hyperparathyroidism and coexistent sarcoidosis.
  • CONTEXT: PTH is excessively secreted to develop hypercalcemia and accelerate bone turnover in patients with primary hyperparathyroidism.
  • PTH stimulates the production of 1,25-dihydroxyvitamin D [1,25(OH)2D] that in turn suppresses the synthesis of PTH in parathyroid cells.
  • OBJECTIVE: The objective of the study was to clarify whether 1,25(OH)2D indeed inhibits circulating levels of PTH and influences bone turnover, even in a patient with primary hyperparathyroidism.
  • DESIGN, SETTING, AND PATIENT: We evaluated PTH levels in a patient with primary hyperparathyroidism and coexistent sarcoidosis whose serum 1,25(OH)2D levels were independent of PTH.
  • INTERVENTIONS AND MAIN OUTCOME MEASURES: The present case was treated with prednisolone before and after surgical resection of parathyroid adenoma, and Ca-regulating hormones and bone markers were measured.
  • RESULTS: Serum Ca and PTH levels significantly decreased after parathyroid surgery, whereas serum 1,25(OH)2D levels remained high.
  • Urine N-telopeptides, serum osteocalcin, and bone-type alkaline phosphatase all decreased to physiological ranges after parathyroid surgery.
  • CONCLUSIONS: These results suggest that 1,25(OH)2D indeed inhibits the production of PTH not to exacerbate hypercalcemia in a patient with primary hyperparathyroidism.
  • [MeSH-major] Hyperparathyroidism, Primary / complications. Hyperparathyroidism, Primary / metabolism. Parathyroid Hormone / antagonists & inhibitors. Parathyroid Hormone / blood. Sarcoidosis / complications. Vitamin D / analogs & derivatives


68. Khoo TK, Baker CH, Abu-Lebdeh HS, Wermers RA: Suppressibility of parathyroid hormone in primary hyperparathyroidism. Endocr Pract; 2007 Nov-Dec;13(7):785-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Suppressibility of parathyroid hormone in primary hyperparathyroidism.
  • OBJECTIVE: To describe an unusual case of pathologically confirmed primary hyperparathyroidism in a patient presenting with severe hypercalcemia and an undetectable parathyroid hormone (PTH) level.
  • In addition, the possible causes of low serum PTH levels in the setting of primary hyperparathyroidism are discussed.
  • One week after the patient was dismissed from the hospital, repeated laboratory studies showed a serum calcium value of 11.1 mg/dL, a serum phosphorus level of 2.8 mg/dL, and an elevated PTH concentration of 11.0 pmol/L, consistent with primary hyperparathyroidism.
  • A parathyroid scan showed a parathyroid adenoma in the left lower neck area, and she subsequently underwent successful surgical resection of a pathologically confirmed parathyroid adenoma.
  • CONCLUSION: This case demonstrates that the serum PTH level can be suppressed in patients with primary hyperparathyroidism.
  • [MeSH-major] Hyperparathyroidism, Primary / diagnosis. Parathyroid Hormone / blood
  • [MeSH-minor] Abdominal Pain. Acute Disease. Adenoma / complications. Adenoma / surgery. Adolescent. Amylases / blood. Female. Humans. Hypercalcemia / blood. Hypercalcemia / etiology. Lipase / blood. Nausea. Pancreatitis / complications. Pancreatitis / enzymology. Parathyroid Neoplasms / complications. Parathyroid Neoplasms / surgery. Phosphorus / blood. Thyrotropin / blood. Thyroxine / blood. Triiodothyronine / blood. Vitamin D / analogs & derivatives. Vitamin D / blood. Vomiting

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • Hazardous Substances Data Bank. LEVOTHYROXINE .
  • Hazardous Substances Data Bank. LIOTHYRONINE .
  • Hazardous Substances Data Bank. PHOSPHORUS, ELEMENTAL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18194938.001).
  • [ISSN] 1934-2403
  • [Journal-full-title] Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
  • [ISO-abbreviation] Endocr Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Parathyroid Hormone; 06LU7C9H1V / Triiodothyronine; 1406-16-2 / Vitamin D; 27YLU75U4W / Phosphorus; 66772-14-3 / 1,25-dihydroxyvitamin D; 9002-71-5 / Thyrotropin; EC 3.1.1.3 / Lipase; EC 3.2.1.- / Amylases; Q51BO43MG4 / Thyroxine
  •  go-up   go-down


69. Abikhzer G, Levental M, Rush C: High resolution MRI in the detection of an intrathymic parathyroid adenoma. Br J Radiol; 2006 Sep;79(945):e78-80
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] High resolution MRI in the detection of an intrathymic parathyroid adenoma.
  • The most common cause of primary hyperparathyroidism is parathyroid adenoma.
  • Multiple imaging techniques have been utilized in the detection of ectopic adenoma and are discussed.
  • We report on a case of an intrathymic parathyroid adenoma that was detected through the novel use of a breast coil in performing a high resolution MRI.
  • [MeSH-major] Adenoma / diagnosis. Magnetic Resonance Imaging / methods. Parathyroid Neoplasms / diagnosis
  • [MeSH-minor] Adult. Female. Humans. Hyperparathyroidism, Primary / etiology

  • MedlinePlus Health Information. consumer health - MRI Scans.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16940365.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  •  go-up   go-down


70. Padmanabhan H: Cinacalcet in the treatment of intractable hypercalcemia following two neck exploration surgeries for primary hyperparathyroidism. South Med J; 2010 Mar;103(3):272-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cinacalcet in the treatment of intractable hypercalcemia following two neck exploration surgeries for primary hyperparathyroidism.
  • Primary hyperparathyroidism is commonly due to a single, sporadic parathyroid adenoma, and surgery is considered the treatment of choice based on guidelines established by the National Institutes of Health consensus panel.
  • [MeSH-major] Hypercalcemia / drug therapy. Hyperparathyroidism, Primary / complications. Naphthalenes / therapeutic use. Parathyroid Neoplasms / complications. Receptors, Calcium-Sensing / agonists

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20134376.001).
  • [ISSN] 1541-8243
  • [Journal-full-title] Southern medical journal
  • [ISO-abbreviation] South. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Naphthalenes; 0 / Receptors, Calcium-Sensing; 1K860WSG25 / Cinacalcet Hydrochloride
  •  go-up   go-down


71. Verlaan L, van der Wal B, de Maat GJ, Walenkamp G, Nollen-Lopez L, van Ooij A: Primary hyperparathyroidism and pathological fractures: a review. Acta Orthop Belg; 2007 Jun;73(3):300-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary hyperparathyroidism and pathological fractures: a review.
  • Primary hyperparathyroidism is due most often to a parathyroid adenoma secreting parathyroid hormone.
  • [MeSH-major] Fractures, Spontaneous / etiology. Hyperparathyroidism, Primary / complications

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17715718.001).
  • [ISSN] 0001-6462
  • [Journal-full-title] Acta orthopaedica Belgica
  • [ISO-abbreviation] Acta Orthop Belg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Belgium
  • [Number-of-references] 28
  •  go-up   go-down


72. Westin G, Björklund P, Akerström G: Molecular genetics of parathyroid disease. World J Surg; 2009 Nov;33(11):2224-33
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Molecular genetics of parathyroid disease.
  • BACKGROUND: Primary hyperparathyroidism (HPT) is often caused by a benign parathyroid tumor, adenoma; less commonly by multiglandular parathyroid disease/hyperplasia; and rarely by parathyroid carcinoma.
  • Improved knowledge of the molecular background of parathyroid tumor development may help select patients for appropriate surgical treatment and can eventually provide new means of treatment.
  • The present contribution summarizes more recent knowledge of parathyroid molecular genetics.
  • METHODS: A literature search and review was made to evaluate the level of evidence concerning molecular biology and genetics of primary, secondary, and familial HPT according to criteria proposed by Sackett, with recommendation grading by Heinrich et al.
  • RESULTS: Most parathyroid adenomas and hyperplastic glands are monoclonal lesions.
  • Cyclin D1 gene (CCND1) translocation and oncogene action occur in 8% of adenomas; cyclin D1 overexpression is seen in 20% to 40% of parathyroid adenomas and in 31% of secondary hyperplastic glands.
  • Somatic loss of one MEN1 allele is seen in 25% to 40% of sporadic parathyroid adenomas, half of which have inactivating mutation of the remaining allele.
  • Inactivating somatic HRPT2 mutations are common in parathyroid carcinoma, often causing decreased expression of the protein parafibromin involved in cyclin D1 regulation.
  • Aberrant regulation of Wnt/beta-catenin signaling may be important for parathyroid tumor development.
  • CONCLUSIONS: Molecular genetic studies of parathyroid tumors are well designed basic experimental studies providing strong level III evidence, with data frequently confirmed by subsequent studies.
  • [MeSH-major] Genes, bcl-1 / genetics. Parathyroid Diseases / genetics
  • [MeSH-minor] Animals. Humans. Mice. Parathyroid Neoplasms / genetics

  • MedlinePlus Health Information. consumer health - Parathyroid Disorders.
  • COS Scholar Universe. author profiles.
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Nat Clin Pract Endocrinol Metab. 2007 Feb;3(2):122-33 [17237839.001]
  • [Cites] J Clin Endocrinol Metab. 1996 May;81(5):1736-9 [8626826.001]
  • [Cites] J Surg Oncol. 2005 Mar 1;89(3):136-42 [15719375.001]
  • [Cites] Clin Endocrinol (Oxf). 2002 Jan;56(1):113-7 [11849254.001]
  • [Cites] Cancer Res. 2004 Oct 15;64(20):7405-11 [15492263.001]
  • [Cites] Curr Opin Oncol. 2004 Jan;16(1):1-7 [14685084.001]
  • [Cites] Nat Rev Cancer. 2005 May;5(5):367-75 [15864278.001]
  • [Cites] Lab Invest. 2001 Apr;81(4):527-33 [11304572.001]
  • [Cites] Eur J Endocrinol. 2005 Mar;152(3):459-70 [15757864.001]
  • [Cites] J Clin Endocrinol Metab. 2000 Nov;85(11):4113-7 [11095441.001]
  • [Cites] J Endocrinol. 2000 Jul;166(1):1-9 [10856877.001]
  • [Cites] Nat Genet. 2002 Dec;32(4):676-80 [12434154.001]
  • [Cites] World J Surg. 1996 Sep;20(7):744-50; discussion 750-2 [8678945.001]
  • [Cites] Hum Mutat. 2009 Jan;30(1):85-92 [18712808.001]
  • [Cites] J Am Soc Nephrol. 2002 Jun;13(6):1490-8 [12039978.001]
  • [Cites] Best Pract Res Clin Rheumatol. 2008 Mar;22(1):129-48 [18328986.001]
  • [Cites] J Clin Endocrinol Metab. 1993 Jan;76(1):139-44 [8421078.001]
  • [Cites] Science. 2007 Jun 15;316(5831):1615-8 [17569864.001]
  • [Cites] Cell. 2005 Oct 21;123(2):207-18 [16239140.001]
  • [Cites] J Clin Endocrinol Metab. 2000 Dec;85(12):4789-94 [11134144.001]
  • [Cites] Int J Oncol. 2002 Oct;21(4):727-35 [12239610.001]
  • [Cites] Diagn Mol Pathol. 2001 Dec;10(4):242-7 [11763315.001]
  • [Cites] Nephrol Dial Transplant. 2005 Dec;20(12):2636-45 [16204278.001]
  • [Cites] Nat Clin Pract Endocrinol Metab. 2006 Oct;2(10):562-70 [17024155.001]
  • [Cites] Surgery. 1998 Sep;124(3):484-90 [9736899.001]
  • [Cites] Science. 2007 Aug 10;317(5839):803-6 [17690294.001]
  • [Cites] Curr Opin Genet Dev. 2007 Feb;17(1):45-51 [17208432.001]
  • [Cites] Mol Cancer. 2008 Jun 09;7:53 [18541010.001]
  • [Cites] Nature. 1997 Nov 6;390(6655):45-51 [9363890.001]
  • [Cites] Cancer. 2009 Jan 15;115(2):334-44 [19107770.001]
  • [Cites] Biochem Biophys Res Commun. 2007 Jan 12;352(2):532-6 [17126301.001]
  • [Cites] J Clin Endocrinol Metab. 2002 Jun;87(6):2967-72 [12050281.001]
  • [Cites] Clin Cancer Res. 1998 Jan;4(1):211-4 [9516973.001]
  • [Cites] Semin Surg Oncol. 1997 Mar-Apr;13(2):104-13 [9088066.001]
  • [Cites] J Clin Invest. 2007 Dec;117(12):4003-8 [17992255.001]
  • [Cites] J Clin Endocrinol Metab. 2002 Dec;87(12 ):5826-9 [12466393.001]
  • [Cites] Hum Mutat. 2008 Jan;29(1):22-32 [17879353.001]
  • [Cites] Ann Otol Rhinol Laryngol. 2007 Dec;116(12):928-33 [18217513.001]
  • [Cites] Surgery. 1997 Mar;121(3):287-94 [9092129.001]
  • [Cites] J Clin Endocrinol Metab. 1998 Aug;83(8):2627-30 [9709922.001]
  • [Cites] Curr Opin Oncol. 2006 Jan;18(1):16-22 [16357559.001]
  • [Cites] Oncogene. 2005 Feb 10;24(7):1272-6 [15580289.001]
  • [Cites] N Engl J Med. 1989 Jul 27;321(4):213-8 [2568586.001]
  • [Cites] Mol Endocrinol. 2005 Oct;19(10):2603-9 [15928311.001]
  • [Cites] Eur J Surg. 1997 May;163(5):331-7 [9195165.001]
  • [Cites] Am J Surg Pathol. 2006 Sep;30(9):1140-9 [16931959.001]
  • [Cites] Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):10770-5 [12960363.001]
  • [Cites] J Clin Endocrinol Metab. 1999 Oct;84(10):3775-80 [10523029.001]
  • [Cites] Hum Genet. 1997 Mar;99(3):342-9 [9050920.001]
  • [Cites] Eur J Endocrinol. 2000 Jul;143(1):47-54 [10870030.001]
  • [Cites] Mod Pathol. 1999 Apr;12(4):412-6 [10229506.001]
  • [Cites] Clin Endocrinol (Oxf). 2002 Oct;57(4):501-5 [12354132.001]
  • [Cites] Science. 1997 Apr 18;276(5311):404-7 [9103196.001]
  • [Cites] Nature. 2000 Jul 13;406(6792):199-203 [10910362.001]
  • [Cites] J Clin Endocrinol Metab. 1993 Nov;77(5):1108-12 [8077300.001]
  • [Cites] Nat Genet. 1997 Aug;16(4):375-8 [9241276.001]
  • [Cites] Kidney Int. 1999 Apr;55(4):1375-83 [10201002.001]
  • [Cites] Ann Surg. 2006 Feb;243(2):154-68 [16432347.001]
  • [Cites] PLoS Med. 2007 Nov 27;4(11):e328 [18044981.001]
  • [Cites] Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):749-54 [15640349.001]
  • [Cites] Med Lab Sci. 1987 Apr;44(2):115-8 [3695842.001]
  • [Cites] N Engl J Med. 1977 Sep 29;297(13):696-8 [895789.001]
  • [Cites] Cancer Res. 2000 Oct 1;60(19):5553-7 [11034102.001]
  • [Cites] Eur J Pediatr. 2004 Oct;163(10):589-94 [15241688.001]
  • [Cites] Chest. 1989 Feb;95(2 Suppl):2S-4S [2914516.001]
  • [Cites] Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3837-42 [11274402.001]
  • [Cites] J Pathol. 2004 Jan;202(1):86-94 [14694525.001]
  • [Cites] Endocr Relat Cancer. 2005 Dec;12(4):929-37 [16322332.001]
  • [Cites] Curr Med Chem. 2008;15(2):178-86 [18220773.001]
  • [Cites] J Clin Invest. 1985 Jan;75(1):49-57 [3965511.001]
  • [Cites] J Clin Invest. 1995 May;95(5):2047-53 [7738171.001]
  • [Cites] Science. 2005 Oct 21;310(5747):490-3 [16239475.001]
  • [Cites] Hum Pathol. 1986 May;17(5):520-7 [3699813.001]
  • [Cites] Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14659-64 [16195383.001]
  • [Cites] Cell. 1999 Jan 8;96(1):143-52 [9989505.001]
  • [Cites] Surgery. 2005 Dec;138(6):1111-20; discussion 1120 [16360398.001]
  • [Cites] Nephrol Dial Transplant. 2008 Nov;23(11):3397-402 [18495742.001]
  • [Cites] J Clin Endocrinol Metab. 2000 May;85(5):2000-3 [10843188.001]
  • [Cites] J Biol Chem. 2006 Mar 10;281(10):6120-3 [16436388.001]
  • [Cites] J Biol Chem. 2001 Mar 23;276(12):8727-33 [11118432.001]
  • [Cites] World J Surg. 2006 May;30(5):705-13 [16680586.001]
  • [Cites] J Clin Endocrinol Metab. 2000 May;85(5):2042-7 [10843194.001]
  • [Cites] Clin Cancer Res. 2004 Oct 1;10(19):6629-37 [15475453.001]
  • [Cites] Clin Endocrinol (Oxf). 2008 Feb;68(2):271-7 [17803708.001]
  • [Cites] Neoplasia. 2007 Jul;9(7):533-5 [17710155.001]
  • [Cites] J Clin Endocrinol Metab. 2006 Dec;91(12):5019-21 [17003089.001]
  • [Cites] J Clin Endocrinol Metab. 2007 Jan;92(1):338-44 [17047023.001]
  • [Cites] Ann Surg Oncol. 2005 May;12(5):412-6 [15915376.001]
  • [Cites] J Clin Endocrinol Metab. 1998 Jul;83(7):2255-9 [9661591.001]
  • [Cites] J Med Genet. 2003 Sep;40(9):657-63 [12960210.001]
  • [Cites] J Clin Endocrinol Metab. 2007 Apr;92(4):1564-6 [17284619.001]
  • [Cites] N Engl J Med. 1990 Nov 8;323(19):1324-8 [2215618.001]
  • [Cites] Am J Surg Pathol. 2005 Aug;29(8):1049-55 [16006799.001]
  • [Cites] World J Surg. 1988 Aug;12(4):431-8 [3420928.001]
  • [Cites] J Clin Endocrinol Metab. 2002 Aug;87(8):3911-4 [12161532.001]
  • [Cites] J Endocrinol. 2007 Oct;195(1):125-31 [17911404.001]
  • [Cites] J Bone Miner Res. 1999 Jun;14(6):878-82 [10352095.001]
  • [Cites] J Clin Invest. 2001 May;107(9):1093-102 [11342573.001]
  • [Cites] Clin Endocrinol (Oxf). 2006 Dec;65(6):806-9 [17121534.001]
  • [Cites] Kidney Int. 1997 Jan;51(1):328-36 [8995751.001]
  • [Cites] J Clin Endocrinol Metab. 1989 May;68(5):976-81 [2541161.001]
  • [Cites] Hum Mol Genet. 1997 Jul;6(7):1177-83 [9215690.001]
  • [Cites] Clin Endocrinol (Oxf). 2000 Mar;52(3):339-48 [10718832.001]
  • [Cites] Mol Cell. 2004 Feb 27;13(4):587-97 [14992727.001]
  • [Cites] Nat Med. 1995 Dec;1(12):1309-11 [7489414.001]
  • [Cites] J Clin Endocrinol Metab. 1997 Oct;82(10):3481-6 [9329389.001]
  • [Cites] Endocr Relat Cancer. 2007 Jun;14(2):501-12 [17639063.001]
  • [Cites] Biochim Biophys Acta. 1999 Oct 6;1447(1):51-6 [10500243.001]
  • [Cites] Endocr Relat Cancer. 2008 Mar;15(1):267-75 [18310293.001]
  • [Cites] Br J Surg. 2005 Nov;92(11):1345-53 [16237743.001]
  • [Cites] N Engl J Med. 2003 Oct 30;349(18):1722-9 [14585940.001]
  • [Cites] Oncogene. 2008 Nov 27;27(56):7094-105 [18762812.001]
  • [Cites] Oncogene. 2001 Aug 16;20(36):4917-25 [11526476.001]
  • [Cites] J Cell Biol. 2008 Aug 11;182(3):459-65 [18678710.001]
  • [Cites] J Clin Invest. 1989 Jun;83(6):2034-40 [2723071.001]
  • [Cites] Clin Endocrinol (Oxf). 2000 Sep;53(3):373-81 [10971456.001]
  • [Cites] Genes Chromosomes Cancer. 2008 Aug;47(8):639-48 [18398822.001]
  • [Cites] Clin Chem. 1979 Oct;25(10):1806-9 [476930.001]
  • [Cites] Crit Rev Clin Lab Sci. 2005;42(1):35-70 [15697170.001]
  • [Cites] Trends Endocrinol Metab. 2006 Nov;17(9):357-64 [16997566.001]
  • [Cites] Int J Oncol. 2009 Feb;34(2):481-92 [19148484.001]
  • [Cites] J Clin Endocrinol Metab. 1995 Nov;80(11):3107-10 [7593409.001]
  • [Cites] Surgery. 2004 Dec;136(6):1261-6 [15657585.001]
  • [Cites] Clin J Am Soc Nephrol. 2007 Sep;2(5):898-905 [17702710.001]
  • [Cites] J Endocrinol. 1988 Mar;116(3):457-64 [3351432.001]
  • [Cites] J Clin Endocrinol Metab. 1993 May;76(5):1373-5 [7684395.001]
  • [Cites] Biochem Biophys Res Commun. 2006 Jan 20;339(3):827-32 [16325773.001]
  • [Cites] Eur J Endocrinol. 2007 May;156(5):547-54 [17468190.001]
  • [Cites] Eur J Endocrinol. 2002 Nov;147(5):671-5 [12444900.001]
  • [Cites] Kidney Int. 2008 May;73(10):1137-40 [18288099.001]
  • [Cites] Cancer Res. 2003 Nov 15;63(22):8022-8 [14633735.001]
  • [Cites] Adv Anat Pathol. 2005 Mar;12(2):53-61 [15731573.001]
  • [Cites] Cancer Invest. 2008 Mar;26(2):185-92 [18259951.001]
  • [Cites] Nature. 1991 Apr 11;350(6318):512-5 [1826542.001]
  • [Cites] Cancer Res. 2003 Oct 1;63(19):6135-9 [14559791.001]
  • [Cites] Kidney Int. 1998 Mar;53(3):556-61 [9507199.001]
  • [Cites] J Clin Endocrinol Metab. 1998 Aug;83(8):2960-3 [9709976.001]
  • [Cites] Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3455-60 [18308935.001]
  • [Cites] Eur J Endocrinol. 2001 Oct;145(4):415-20 [11580998.001]
  • [Cites] Am J Pathol. 2002 Oct;161(4):1299-306 [12368203.001]
  • [Cites] Mol Cell Biol. 2005 Jan;25(2):612-20 [15632063.001]
  • [Cites] Cancer Lett. 2002 Jan 25;175(2):175-9 [11741745.001]
  • [Cites] Clin Endocrinol (Oxf). 2007 Mar;66(3):399-404 [17302875.001]
  • [Cites] J Endocrinol Invest. 2002 Jun;25(6):508-12 [12109621.001]
  • [Cites] Nature. 2006 Dec 7;444(7120):770-4 [17086194.001]
  • [Cites] N Engl J Med. 1988 Mar 17;318(11):658-62 [3344017.001]
  • [Cites] J Clin Endocrinol Metab. 2008 Oct;93(10):4152-7 [18682507.001]
  • [Cites] Kidney Int. 2008 Sep;74(6):732-9 [18547997.001]
  • [Cites] Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):4040-5 [9520489.001]
  • [Cites] Cancer. 1985 Oct 1;56(7):1529-33 [4027889.001]
  • [Cites] J Clin Endocrinol Metab. 2002 Aug;87(8):3961-5 [12161540.001]
  • [Cites] Clin Endocrinol (Oxf). 2004 Mar;60(3):389-93 [15009006.001]
  • [Cites] Bone Miner. 1988 Jun;4(2):123-32 [3191276.001]
  • [Cites] Am J Pathol. 2004 Aug;165(2):565-76 [15277230.001]
  • [Cites] J Clin Pathol. 1970 May;23(4):362-9 [5430425.001]
  • [Cites] Arch Pathol Lab Med. 2007 Jan;131(1):126-30 [17227113.001]
  • [Cites] Mol Cell Biol. 2007 May;27(9):3417-28 [17339340.001]
  • [Cites] Clin Endocrinol (Oxf). 2007 Sep;67(3):370-6 [17555500.001]
  • (PMID = 19373510.001).
  • [ISSN] 1432-2323
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  •  go-up   go-down


73. Akin M, Atasever T, Kurukahvecioglu O, Dogan M, Gokaslan D, Poyraz A, Koksal H, Taneri F: Preoperative detection of parathyroid adenomas with Tc-99m MIBI and Tc-99m pertechnetate scintigraphy: histopathological and biochemical correlation with Tc-99m MIBI uptake. Bratisl Lek Listy; 2009;110(3):166-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Preoperative detection of parathyroid adenomas with Tc-99m MIBI and Tc-99m pertechnetate scintigraphy: histopathological and biochemical correlation with Tc-99m MIBI uptake.
  • AIM: The objective of this study was to compare the dual phase MIBI scinitgraphy with MIBI and Tc-99m pertechnetate (MIBI + Tc-99m) study in defining the parathyroid adenomas, and to evaluate the effect of histologic and biochemical characteristics on the imaging of parathyroid adenomas with Tc-99m methoxyisobutylisonitrile (MIBI) scintigraphy.
  • METHODS: Thirty-six patients with parathyroid adenomas were studied prospectively.
  • MIBI uptake of adenomas correlated with oxyphill, chief cell and tumour weight of the surgically excised glands.
  • RESULTS: A total of 38 parathyroid adenomas were surgically excised from 36 patients.
  • MIBI + Tc-99m identified 35 of the parathyroid lesions (92%).
  • Whereas, MIBI study detected 30 of the 38 parathyroid adenomas (79% sensitivity) (p=0.0001).
  • Adenoma weight showed significiant correlation with MIBI uptake (p=0.001).
  • CONCLUSION: MIBI + Tc-99m pertechnetate interpretation is more sensitive than only dual MIBI imaging for the detection of parathyroid adenoma.
  • Oxyphill cell content and weight of the lesions proved to be important determinants of 99mTc-MIBI accumulation in parathyroid adenoma.
  • [MeSH-major] Adenoma / radionuclide imaging. Parathyroid Neoplasms / radionuclide imaging. Radiopharmaceuticals. Sodium Pertechnetate Tc 99m. Technetium Tc 99m Sestamibi
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Male. Middle Aged. Parathyroid Glands / radionuclide imaging. Young Adult

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19507637.001).
  • [ISSN] 0006-9248
  • [Journal-full-title] Bratislavské lekárske listy
  • [ISO-abbreviation] Bratisl Lek Listy
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Slovakia
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi; A0730CX801 / Sodium Pertechnetate Tc 99m
  •  go-up   go-down


74. Shim WS, Kim IK, Yoo SD, Kim DH: Non-functional parathyroid adenoma presenting as a massive cervical hematoma: a case report. Clin Exp Otorhinolaryngol; 2008 Mar;1(1):46-8
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Non-functional parathyroid adenoma presenting as a massive cervical hematoma: a case report.
  • Parathyroid adenoma usually manifests with symptoms related to hypercalcemia, such as urinary stone and bone fracture.
  • However, spontaneous cervical hematoma may occur very rarely as a result of extracapsular hemorrhage of a cervical parathyroid adenoma causing acute painful cervical swelling, bruising, dyspnea, hoarseness and dysphagia.
  • We report a 44-year-old woman who manifested as a spontaneous cervical hematoma without any clinical evidence of hyperparathyroidism.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Otolaryngol Head Neck Surg. 2006 Apr;134(4):710-2 [16564403.001]
  • [Cites] Aust N Z J Surg. 1998 Aug;68(8):619-21 [9715147.001]
  • [Cites] Head Neck. 1998 Jul;20(4):350-3 [9588708.001]
  • [Cites] J Laryngol Otol. 1997 Jun;111(6):585-7 [9231101.001]
  • [Cites] Surgery. 1997 Jun;121(6):704-7 [9186472.001]
  • [Cites] Surg Today. 2001;31(3):222-4 [11318124.001]
  • [Cites] Jpn J Clin Oncol. 2004 Mar;34(3):155-8 [15078912.001]
  • [Cites] Surg Today. 2003;33(5):354-7 [12734730.001]
  • [Cites] Surg Today. 2002;32(9):809-11 [12203060.001]
  • [Cites] Intern Med J. 2002 Apr;32(4):179-82 [11951931.001]
  • [Cites] Emerg Radiol. 2004 Feb;10(4):213-5 [15290495.001]
  • (PMID = 19434262.001).
  • [ISSN] 1976-8710
  • [Journal-full-title] Clinical and experimental otorhinolaryngology
  • [ISO-abbreviation] Clin Exp Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2671752
  • [Keywords] NOTNLM ; Hematoma / Neck / Parathyroid neoplasm
  •  go-up   go-down


75. Eloy JA, Mitty H, Genden EM: Preoperative selective venous sampling for nonlocalizing parathyroid adenomas. Thyroid; 2006 Aug;16(8):787-90
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Preoperative selective venous sampling for nonlocalizing parathyroid adenomas.
  • INTRODUCTION: Preoperative parathyroid adenoma localization allows for a minimally invasive surgical approach.
  • Current methods used for adenoma localization include ultrasound, sestamibi scan, and occasionally magnetic resonance imaging (MRI).
  • In cases in which an adenoma is not localized after a radiologic work-up, the surgeon must perform a four-gland exploration.
  • Preoperative selective venous sampling (SVS) has been described as a safe and clinically effective method to localize a parathyroid adenoma after failed exploration.
  • The purpose of this study was to evaluate the efficacy of SVS as a primary localization technique in cases where conventional localization techniques have failed.
  • MATERIALS AND METHODS: Fourteen patients with nonlocalizing parathyroid adenomas after ultrasonography, sestamibi scanning, and MRI were retrospectively reviewed.
  • Eight patients underwent SVS prior to surgery and six patients underwent a four-gland neck exploration without preoperative Svs. The two groups were assessed for accuracy of the SVS in localizing the adenoma, operative time, length of hospitalization, and complications.
  • The SVS proved accurate in preoperatively localizing the adenoma in 7 of 8 patients and allowed for a minimally invasive approach in 87% of patients.
  • CONCLUSION: This study suggests that preoperative SVS may represent a safe and effective method of preoperatively localizing the nonlocalized parathyroid adenoma.
  • In cases where conventional radiologic techniques fail to localize an adenoma, SVS may obviate the need for a four-gland exploration.
  • [MeSH-major] Magnetic Resonance Imaging / methods. Parathyroid Neoplasms / pathology. Parathyroid Neoplasms / radionuclide imaging. Technetium Tc 99m Sestamibi

  • MedlinePlus Health Information. consumer health - MRI Scans.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16910882.001).
  • [ISSN] 1557-9077
  • [Journal-full-title] Thyroid : official journal of the American Thyroid Association
  • [ISO-abbreviation] Thyroid
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


76. Cavallaro G, Cucina A, Coluccia P, Petramala L, Cotesta D, Polistena A, Zinnamosca L, Letizia C, Rosato L, Cavallaro A, De Toma G: Role of growth factors on human parathyroid adenoma cell proliferation. World J Surg; 2010 Jan;34(1):48-54
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Role of growth factors on human parathyroid adenoma cell proliferation.
  • INTRODUCTION: Primary hyperparathyroidism (pHPT) is caused by a single monoclonal adenoma in more than 80% of patients.
  • METHODS: Parathyroid cell cultures were prepared from six human adenomatous parathyroid glands that were surgically removed.
  • CONCLUSIONS: Growth factors seem to play an important role in parathyroid adenoma cell proliferation; IGF-1, bFGF, VEGF, and low-dose TGF-beta1 promote cell proliferation, whereas high-dose TGF-beta1 inhibits these phenomena.
  • [MeSH-major] Adenoma / pathology. Cell Proliferation / drug effects. Fibroblast Growth Factor 2 / pharmacology. Insulin-Like Growth Factor I / pharmacology. Parathyroid Neoplasms / pathology. Transforming Growth Factor beta1 / pharmacology. Vascular Endothelial Growth Factor A / pharmacology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] World J Surg. 1994 Jul-Aug;18(4):635-41; discussion 641-2 [7536995.001]
  • [Cites] Otolaryngol Clin North Am. 2004 Aug;37(4):819-31, x [15262518.001]
  • [Cites] J Clin Endocrinol Metab. 2004 Jun;89(6):2890-6 [15181073.001]
  • [Cites] Eur J Endocrinol. 2006 Jun;154(6):827-33 [16728542.001]
  • [Cites] Physiol Res. 2004;53(1):83-9 [14984318.001]
  • [Cites] World J Surg. 1998 Jun;22(6):520-5 [9597922.001]
  • [Cites] N Engl J Med. 1999 Oct 21;341(17):1249-55 [10528034.001]
  • [Cites] Curr Biol. 1995 May 1;5(5):500-7 [7583099.001]
  • [Cites] Neuro Endocrinol Lett. 2004 Oct;25(5):356-60 [15580170.001]
  • [Cites] APMIS. 2001 Dec;109(12):870-4 [11846729.001]
  • [Cites] Cancer Surv. 1993;16:201-13 [8348536.001]
  • [Cites] J Bone Miner Res. 1998 Mar;13(3):354-62 [9525335.001]
  • [Cites] Cell. 1990 Nov 2;63(3):515-24 [2171777.001]
  • [Cites] Cancer Res. 1995 Jan 15;55(2):249-52 [7812953.001]
  • [Cites] J Surg Res. 2005 Aug;127(2):70-9 [15922362.001]
  • [Cites] WormBook. 2005 Sep 21;:1-16 [18050422.001]
  • [Cites] Metabolism. 2007 Jan;56(1):30-6 [17161223.001]
  • [Cites] Anticancer Res. 1989 Nov-Dec;9(6):1925-35 [2697193.001]
  • [Cites] World J Surg. 2006 May;30(5):714-20 [16680587.001]
  • [Cites] Eur J Clin Invest. 2001 Jul;31(7):610-6 [11454016.001]
  • [Cites] J Bone Miner Metab. 2002;20(4):190-5 [12115063.001]
  • [Cites] Kidney Int. 2003 Dec;64(6):2311-7 [14633156.001]
  • [Cites] Horm Metab Res. 2004 Jul;36(7):480-4 [15305232.001]
  • [Cites] World J Surg. 2006 Mar;30(3):333-45 [16485066.001]
  • [Cites] Horm Metab Res. 2003 Nov-Dec;35(11-12):740-50 [14710353.001]
  • [Cites] Curr Drug Targets Immune Endocr Metabol Disord. 2002 Jul;2(2):167-79 [12476790.001]
  • [Cites] Curr Opin Nephrol Hypertens. 1996 Jan;5(1):35-44 [8834160.001]
  • [Cites] Physiol Rev. 1996 Oct;76(4):1005-26 [8874492.001]
  • [Cites] Ann Intern Med. 1995 Jan 1;122(1):54-9 [7619109.001]
  • (PMID = 20020293.001).
  • [ISSN] 1432-2323
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Transforming Growth Factor beta1; 0 / Vascular Endothelial Growth Factor A; 103107-01-3 / Fibroblast Growth Factor 2; 67763-96-6 / Insulin-Like Growth Factor I
  •  go-up   go-down


77. Starker LF, Delgado-Verdugo A, Udelsman R, Björklund P, Carling T: Expression and somatic mutations of SDHAF2 (SDH5), a novel endocrine tumor suppressor gene in parathyroid tumors of primary hyperparathyroidism. Endocrine; 2010 Dec;38(3):397-401
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression and somatic mutations of SDHAF2 (SDH5), a novel endocrine tumor suppressor gene in parathyroid tumors of primary hyperparathyroidism.
  • To investigate the SDHAF2 gene and its effect on primary hyperparathyroidism.
  • Parathyroid tumors causing primary hyperparathyroidism (pHPT) are one of the more common endocrine neoplasias.
  • Loss of heterozygosity at chromosome 11q13 is the most common chromosomal aberration in parathyroid tumors occurring in about 40% of sporadic tumors.
  • Only 15-19% display somatic mutations in the MEN1 gene, which suggest that this chromosomal region may harbor additional genes of importance in parathyroid tumor development.
  • We demonstrate that the SDHAF2 gene is expressed in parathyroid tissue using RT-PCR.
  • Because detection of inactivating mutations is the major criterion for validating a candidate tumor suppressor, we used automated sequencing of the coding region and intron/exon boundaries in 80 sporadic parathyroid adenomas from patients with pHPT.
  • A known polymorphisms (A to G substitution; rs879647) was identified in 9/80 parathyroid tumors but no tumor-specific somatic mutational aberrations, such as nonsense, frameshift, or other inactivating mutations were identified.
  • The SDHAF2 gene is expressed in parathyroid tissue.
  • However, somatic mutations of the SDHAF2 tumor suppressor gene are unlikely to frequently contribute to parathyroid tumor development in sporadic pHPT.
  • [MeSH-major] Hyperparathyroidism, Primary / genetics. Mitochondrial Proteins / genetics. Mutation. Neuroendocrine Tumors / genetics. Parathyroid Neoplasms / genetics

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Curr Biol. 1999 Jan 28;9(2):R62-5 [10021355.001]
  • [Cites] J Clin Endocrinol Metab. 1989 Sep;69(3):496-9 [2569472.001]
  • [Cites] Nat Genet. 2002 Dec;32(4):676-80 [12434154.001]
  • [Cites] Nat Genet. 2002 Apr;30(4):406-10 [11865300.001]
  • [Cites] Science. 2009 Aug 28;325(5944):1139-42 [19628817.001]
  • [Cites] Surgery. 1997 Mar;121(3):287-94 [9092129.001]
  • [Cites] Lancet Oncol. 2010 Apr;11(4):366-72 [20071235.001]
  • [Cites] J Clin Endocrinol Metab. 1998 Aug;83(8):2627-30 [9709922.001]
  • [Cites] Curr Opin Oncol. 2005 Jan;17(1):7-12 [15608505.001]
  • [Cites] Science. 1997 Apr 18;276(5311):404-7 [9103196.001]
  • [Cites] Nat Genet. 1997 Aug;16(4):375-8 [9241276.001]
  • [Cites] J Clin Endocrinol Metab. 2000 May;85(5):2000-3 [10843188.001]
  • [Cites] N Engl J Med. 2009 Feb 19;360(8):765-73 [19228619.001]
  • [Cites] Nat Med. 1995 Dec;1(12):1309-11 [7489414.001]
  • [Cites] Trends Endocrinol Metab. 2001 Mar;12(2):53-8 [11167122.001]
  • [Cites] Oncogene. 2000 Apr 13;19(16):2060-6 [10803467.001]
  • [Cites] Science. 2000 Feb 4;287(5454):848-51 [10657297.001]
  • [Cites] J Clin Invest. 1989 Jun;83(6):2034-40 [2723071.001]
  • [Cites] N Engl J Med. 2002 May 9;346(19):1459-66 [12000816.001]
  • [Cites] BMC Endocr Disord. 2007 Oct 04;7:8 [17916247.001]
  • [Cites] J Clin Endocrinol Metab. 1998 Aug;83(8):2960-3 [9709976.001]
  • [Cites] J Med Genet. 2008 Nov;45(11):689-94 [18978332.001]
  • (PMID = 20972721.001).
  • [ISSN] 1559-0100
  • [Journal-full-title] Endocrine
  • [ISO-abbreviation] Endocrine
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Mitochondrial Proteins; 0 / SDH5 protein, human
  •  go-up   go-down


78. Chudek J, Nagy A, Kokot F, Podwinski A, Wiecek A, Ritz E, Kovacs G: Phosphatemia is related to chromosomal aberrations of parathyroid glands in patients with hyperparathyroidism. J Nephrol; 2007 Mar-Apr;20(2):164-72
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Phosphatemia is related to chromosomal aberrations of parathyroid glands in patients with hyperparathyroidism.
  • BACKGROUND AND AIMS: It has been well documented that gene and DNA alterations occur frequently in benign primary parathyroid adenomas as well as in parathyroid glands with secondary hyperplasia.
  • METHODS: We analyzed the frequency of chromosomal aberrations in adenomas obtained from 25 patients with primary hyperparathyroidism (pHPT) and 60 parathyroid nodules from 20 uremic patients with secondary hyperparathyroidism (sHPT).
  • The relation of chromosomal aberrations to parathyroid hormone, as well as calcium and phosphate serum concentrations, was assessed.
  • RESULTS: Somatic chromosomal aberrations were found in 23 out of 25 adenomas, in hyperplastic lesions from 16 out of 20 patients.
  • CONCLUSION: Hyperphosphatemia may increase the risk of specific and random chromosomal aberrations due to increasing proliferation rate of parathyroid cells in patients with sHPT.
  • [MeSH-major] Chromosome Aberrations. Hyperparathyroidism / blood. Hyperparathyroidism / genetics. Parathyroid Glands / physiopathology. Phosphates / blood
  • [MeSH-minor] Adenoma / genetics. Adenoma / physiopathology. Adult. Aged. Alleles. Calcium / blood. Female. Humans. Hyperparathyroidism, Primary / blood. Hyperparathyroidism, Primary / genetics. Hyperparathyroidism, Secondary / blood. Hyperparathyroidism, Secondary / genetics. Male. Microsatellite Repeats. Middle Aged. Parathyroid Hormone / blood. Parathyroid Neoplasms / genetics

  • Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17514620.001).
  • [ISSN] 1121-8428
  • [Journal-full-title] Journal of nephrology
  • [ISO-abbreviation] J. Nephrol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Parathyroid Hormone; 0 / Phosphates; SY7Q814VUP / Calcium
  •  go-up   go-down


79. Ippolito G, Palazzo FF, Sebag F, De Micco C, Henry JF: Intraoperative diagnosis and treatment of parathyroid cancer and atypical parathyroid adenoma. Br J Surg; 2007 May;94(5):566-70
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intraoperative diagnosis and treatment of parathyroid cancer and atypical parathyroid adenoma.
  • BACKGROUND: Distinction of parathyroid cancer from atypical parathyroid adenoma (APA) at operation is difficult.
  • The aim of this study was to determine whether parathyroid cancer and APA have different operative findings and long-term outcomes.
  • METHODS: A retrospective review was undertaken of patients with suspicious or malignant parathyroid tumours treated between 1974 and 2005.
  • Parathyroid cancer was defined as a lesion with vascular or tissue invasion, and APA as a neoplasm with broad fibrous bands, trabecular growth, mitosis and nuclear atypia.
  • RESULTS: Twenty-seven patients with suspicious or malignant parathyroid tumours were identified.
  • After histological review, parathyroid cancer was confirmed in 11 patients (group 1) and 16 tumours were classified as APA (group 2).
  • CONCLUSION: Operative findings cannot distinguish APA from parathyroid cancer reliably.
  • [MeSH-major] Adenoma / diagnosis. Parathyroid Neoplasms / diagnosis. Parathyroidectomy / methods
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Diagnosis, Differential. Female. Humans. Intraoperative Period. Male. Middle Aged. Neoplasm Recurrence, Local / etiology. Prognosis. Retrospective Studies. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Br J Surg. 2007 Aug;94(8):1043; author reply 1043-4 [17636522.001]
  • [CommentIn] Br J Surg. 2007 Aug;94(8):1042-3; author reply 1043-4 [17636521.001]
  • (PMID = 17380564.001).
  • [ISSN] 0007-1323
  • [Journal-full-title] The British journal of surgery
  • [ISO-abbreviation] Br J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  •  go-up   go-down


80. Boguszewski CL, Bianchet LC, Raskin S, Nomura LM, Borba LA, Cavalcanti TC: Application of genetic testing to define the surgical approach in a sporadic case of multiple endocrine neoplasia type 1. Arq Bras Endocrinol Metabol; 2010 Nov;54(8):705-10
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report the use of a genetic test for therapeutic decision making in a case of primary hyperparathyroidism associated with Cushing's disease (CD).
  • On follow-up, hypercalcemia with high parathyroid hormone (PTH) levels was detected, associated with nephrolithiasis and low bone mineral density in the spine and hip.
  • Parathyroid scintigraphy showed tracer uptake in the inferior region of the left thyroid lobe, and cervical ultrasound showed a heterogeneous nodule in the same area, suggestive of a parathyroid adenoma (PA).
  • Genetic testing detected mutation in the MEN 1 gene and total parathyroidectomy with the implantation of a fragment of one gland in the forearm was performed.
  • Pathology showed a PA and 3 normal parathyroid glands, without hyperplasia, despite the diagnosis of MEN 1.
  • [MeSH-major] Adenoma / genetics. Genetic Testing / standards. Hyperparathyroidism, Primary / genetics. Multiple Endocrine Neoplasia Type 1 / genetics. Parathyroid Neoplasms / genetics


81. Sammarelli G, Zannoni M, Bonomini S, Delsignore R, Rizzoli V, Sianesi M, Caramatti C: A translocation t(4; 13)(q21;q14) as single clonal chromosomal abnormality in a parathyroid adenoma. Tumori; 2007 Jan-Feb;93(1):97-9
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A translocation t(4; 13)(q21;q14) as single clonal chromosomal abnormality in a parathyroid adenoma.
  • Most of the information about the genetic composition of parathyroid tumors has been obtained by comparative genomic hybridization (CGH) and loss of heterozygosity (LOH) studies, whereas only few conventional cytogenetic investigation results are available.
  • We have performed cytogenetic analysis of short-term cultures from 3 parathyroid adenoma tissue samples.
  • Two cases showed a normal karyotype in all the metaphases obtained from independent primary cultures.
  • Further conventional cytogenetic analysis of more parathyroid tumor specimens would be necessary to identify other specific abnormalities and the involved genes with a potential important role in the diagnosis, prognosis and pathogenesis of parathyroid tumors.
  • [MeSH-major] Adenoma / genetics. Chromosome Aberrations. Chromosomes, Human, Pair 13 / genetics. Chromosomes, Human, Pair 4 / genetics. Parathyroid Neoplasms / genetics. Translocation, Genetic

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17455879.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


82. Kebebew E, Hwang J, Reiff E, Duh QY, Clark OH: Predictors of single-gland vs multigland parathyroid disease in primary hyperparathyroidism: a simple and accurate scoring model. Arch Surg; 2006 Aug;141(8):777-82; discussion 782
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Predictors of single-gland vs multigland parathyroid disease in primary hyperparathyroidism: a simple and accurate scoring model.
  • HYPOTHESIS: Preoperative clinical, biochemical, and imaging studies could be used to reliably select patients with single-gland primary hyperparathyroidism who could undergo minimally invasive parathyroidectomy and to determine whether additional perioperative testing is necessary.
  • PATIENTS: A total of 238 patients who underwent neck surgical exploration and parathyroidectomy for primary hyperparathyroidism from January 7, 2002, to December 23, 2004.
  • MAIN OUTCOME MEASURES: Demographic, clinical, biochemical, and imaging factors that predict single-gland vs multigland parathyroid disease, and biochemical cure.
  • RESULTS: Of the 238 patients, 75.2% had a single adenoma, 21.4% had asymmetric 4-gland hyperplasia, and 3.4% had double adenomas.
  • Preoperative calcium and intact parathyroid hormone levels were significantly higher (P = .03 and .04, respectively) and ultrasound and sestamibi scan results were more likely to be positive (both P<.001) in single-gland primary hyperparathyroidism.
  • A dichotomous scoring model based on preoperative total calcium level (>/=3 mmol/L [>/=12 mg/dL]), intact parathyroid hormone level (>/=2 times the upper limit of normal levels), positive ultrasound and sestamibi scan results for 1 enlarged gland, and concordant ultrasound and sestamibi scan findings reliably distinguished single-gland vs multigland cases (P<.001).
  • The positive predictive value of this scoring model to correctly predict single-gland disease was 100% for a total score of 3 or higher.
  • CONCLUSIONS: Preoperative biochemical and imaging study results reliably distinguished single-gland vs multigland parathyroid disease in primary hyperparathyroidism.
  • Our findings suggest that patients with a score of 3 or higher can undergo a minimally invasive parathyroidectomy without the routine use of intraoperative parathyroid hormone or additional imaging studies, and those with a score of less than 3 should have additional testing to ensure that multigland disease is not overlooked.
  • [MeSH-major] Hyperparathyroidism, Primary / diagnosis. Parathyroidectomy / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Calcium / blood. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Male. Middle Aged. Parathyroid Glands / radionuclide imaging. Parathyroid Glands / surgery. Parathyroid Glands / ultrasonography. Parathyroid Hormone / blood. Preoperative Care. Prognosis. ROC Curve. Retrospective Studies. Severity of Illness Index

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16924085.001).
  • [ISSN] 0004-0010
  • [Journal-full-title] Archives of surgery (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Parathyroid Hormone; SY7Q814VUP / Calcium
  •  go-up   go-down


83. Nanji SS, Roth SI: A parathyroid myxoadenoma observed grossly. Endocr Pathol; 2007;18(1):53-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A parathyroid myxoadenoma observed grossly.
  • We are reporting a case of a patient with primary hyperparathyroidism because of an unusual parathyroid adenoma.
  • Though moderate to extensive myxoid alteration of the stroma has been reported in lipoadenomas, to the best of our knowledge, this is the first parathyroid adenoma in which the myxomatous component was recognized grossly and which lacked a stromal adipose component.
  • [MeSH-major] Adenoma / pathology. Mucins / metabolism. Parathyroid Neoplasms / pathology
  • [MeSH-minor] Alkaline Phosphatase / blood. Biomarkers, Tumor / metabolism. Calcium / blood. Humans. Hyperparathyroidism / etiology. Hyperparathyroidism / pathology. Keratins / metabolism. Male. Middle Aged. Parathyroid Hormone / metabolism. Phosphorus / blood. Thyroidectomy

  • Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .
  • Hazardous Substances Data Bank. PHOSPHORUS, ELEMENTAL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Acta Chir Scand. 1987 Oct;153(10):635-9 [3434106.001]
  • [Cites] Arch Anat Cytol Pathol. 1985;33(4):205-8 [4062378.001]
  • [Cites] Otolaryngol Head Neck Surg. 1996 Feb;114(2):313-6 [8637760.001]
  • [Cites] Surgery. 1983 Dec;94(6):901-5 [6648802.001]
  • [Cites] Pathol Res Pract. 1980 Dec;170(4):420-5 [7220392.001]
  • [Cites] Acta Chir Scand. 1971;137(5):478-82 [5149376.001]
  • [Cites] Acta Chir Scand. 1972;138(6):628-9 [5084308.001]
  • [Cites] Cancer. 1958 May-Jun;11(3):601-6 [13523568.001]
  • [Cites] N Engl J Med. 1962 Jan 18;266:121-3 [13859106.001]
  • [Cites] Presse Med. 1985 Sep 28;14(32):1711 [2932730.001]
  • (PMID = 17652802.001).
  • [ISSN] 1046-3976
  • [Journal-full-title] Endocrine pathology
  • [ISO-abbreviation] Endocr. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Mucins; 0 / Parathyroid Hormone; 27YLU75U4W / Phosphorus; 68238-35-7 / Keratins; EC 3.1.3.1 / Alkaline Phosphatase; SY7Q814VUP / Calcium
  •  go-up   go-down


84. Ahmad S, Mufti TS, Khan AA, Ahmad S: Parathyroid carcinoma. J Ayub Med Coll Abbottabad; 2006 Apr-Jun;18(2):84-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Parathyroid carcinoma.
  • Parathyroid carcinoma is a very rare cause of primary hyperparathyroidism and these tumors are usually hyper-functioning as compared to other malignant endocrine tumors.
  • Surgery is the only effective primary treatment.
  • Parathyroid adenoma was initially diagnosed and localized at left lower gland by Sestamibi scan and ultrasonography.
  • She underwent surgery and enlarged parathyroid gland was removed.
  • [MeSH-major] Adenoma / diagnosis. Parathyroid Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged

  • Genetic Alliance. consumer health - Parathyroid carcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16977824.001).
  • [ISSN] 1025-9589
  • [Journal-full-title] Journal of Ayub Medical College, Abbottabad : JAMC
  • [ISO-abbreviation] J Ayub Med Coll Abbottabad
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
  •  go-up   go-down


85. Su AW, Chen CF, Huang CK, Chen PC, Chen WM, Chen TH: Primary hyperparathyroidism with brown tumor mimicking metastatic bone malignancy. J Chin Med Assoc; 2010 Mar;73(3):177-80
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary hyperparathyroidism with brown tumor mimicking metastatic bone malignancy.
  • We report a case of brown tumor caused by parathyroid adenoma.
  • With a systematic approach and awareness of metabolic bone disease, an accurate diagnosis was finally reached.
  • Appropriate treatments, including preventive internal fixation of the impending femoral fracture and surgical excision of the parathyroid adenoma were performed accordingly.
  • The key treatment for the condition was surgical excision of the parathyroid adenoma.
  • After normalization of serum intact-parathyroid hormone level, the bony lesions resolved and required no further orthopedic surgery.
  • [MeSH-major] Bone Neoplasms / diagnosis. Hyperparathyroidism, Primary / complications. Osteitis Fibrosa Cystica / diagnosis
  • [MeSH-minor] Adenoma / complications. Aged. Diagnosis, Differential. Humans. Male. Parathyroid Neoplasms / complications

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • MedlinePlus Health Information. consumer health - Bone Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2010 Elsevier. Published by Elsevier B.V. All rights reserved.
  • (PMID = 20231005.001).
  • [ISSN] 1728-7731
  • [Journal-full-title] Journal of the Chinese Medical Association : JCMA
  • [ISO-abbreviation] J Chin Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
  •  go-up   go-down


86. Orfanos NF, Mariolis-Sapsakos T, Orfanos FN, Goutas N, Vlachodimitropoulos D, Antoniou AG: Giant parathyroid adenoma with atypical ultrasonographic image. Clin Nucl Med; 2007 Mar;32(3):239-41
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant parathyroid adenoma with atypical ultrasonographic image.
  • [MeSH-major] Adenoma / radionuclide imaging. Adenoma / ultrasonography. Parathyroid Neoplasms / radionuclide imaging. Parathyroid Neoplasms / ultrasonography
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged. Radiopharmaceuticals. Technetium Tc 99m Sestamibi

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17314610.001).
  • [ISSN] 0363-9762
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


87. Wosnitzer B, Gadiraju R: The role of nuclear imaging in multiple endocrine neoplasia 1 (MEN 1). Radiol Case Rep; 2010;5(4):452
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Multiple endocrine neoplasia 1 (MEN 1) is a rare genetic disorder classically characterized by a predisposition to tumors of the parathyroid glands, anterior pituitary gland, and pancreatic islet cells (1).
  • In addition to exhibiting these characteristic tumors, MEN 1 patients also have an increased propensity for other tumors such as carcinoids, adrenal adenomas, angiofibromas, and lipomas (1, 2, 3).
  • Diagnosis of MEN 1 is usually made by a combination of history and physical examination, biochemical serum testing, and various imaging modalities (9, 10).
  • We present a classic case of MEN 1 with unique presentation and diagnosis using predominantly nuclear imaging in order to emphasize the role of nuclear imaging in diagnosing and treating MEN 1.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 27307880.001).
  • [ISSN] 1930-0433
  • [Journal-full-title] Radiology case reports
  • [ISO-abbreviation] Radiol Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Other-IDs] NLM/ PMC4901017
  • [Keywords] NOTNLM ; CT, computed tomography / EGD, esophagogastroduodenoscopy / MEN 1, multiple endocrine neoplasia 1 / MRI, magnetic resonance imaging
  •  go-up   go-down


88. Braun B, Blank W: [Ultrasonography of the thyroid and parathyroid gland]. Internist (Berl); 2006 Jul;47(7):729-46; quiz 747
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Ultrasonography of the thyroid and parathyroid gland].
  • Ultrasonography is the most important imaging tool in the diagnosis of thyroid disease.
  • The results of real-time B-imaging of the thyroid gland along with physical signs and basal TSH can aid in the diagnosis of thyroid dysfunction, of for instance, a small, hypoechogenic gland in Hashimoto's and radiation thyroiditis, or an enlarged, hypoechogenic and pulsating gland in Graves' disease.
  • Highly experienced investigators in ultrasound can assist preoperatively in the localization of parathyroid adenomas in primary and tertiary hyperthyroidism (when followed by (99m)Tc szintigraphy plus SPECT).
  • [MeSH-major] Parathyroid Diseases / diagnostic imaging. Parathyroid Glands / diagnostic imaging. Thyroid Diseases / diagnostic imaging. Thyroid Gland / diagnostic imaging. Ultrasonography / methods

  • MedlinePlus Health Information. consumer health - Parathyroid Disorders.
  • MedlinePlus Health Information. consumer health - Thyroid Diseases.
  • MedlinePlus Health Information. consumer health - Ultrasound.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Clin Endocrinol Metab. 2002 May;87(5):1941-6 [11994321.001]
  • [Cites] Ultraschall Med. 2003 Apr;24(2):85-9 [12698372.001]
  • [Cites] N Engl J Med. 2004 Oct 21;351(17 ):1764-71 [15496625.001]
  • [Cites] Thyroid. 2003 Jun;13(6):547-51 [12930598.001]
  • [Cites] Dtsch Med Wochenschr. 1994 Nov 25;119(47):1607-12 [7982370.001]
  • [Cites] J Clin Endocrinol Metab. 1996 Sep;81(9):3261-4 [8784080.001]
  • [Cites] Exp Clin Endocrinol Diabetes. 2001;109(5):250-60 [11507648.001]
  • [Cites] Dtsch Med Wochenschr. 2003 Oct 31;128(44):2324-8 [14593577.001]
  • (PMID = 16680414.001).
  • [ISSN] 0020-9554
  • [Journal-full-title] Der Internist
  • [ISO-abbreviation] Internist (Berl)
  • [Language] ger
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 15
  •  go-up   go-down


89. Alzahrani AS, Al Sheef M: Severe primary hyperparathyroidism masked by asymptomatic celiac disease. Endocr Pract; 2008 Apr;14(3):347-50
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Severe primary hyperparathyroidism masked by asymptomatic celiac disease.
  • OBJECTIVE: To present a case that illustrates the importance of considering asymptomatic celiac disease (CD) as a possible underlying cause in some cases of normocalcemic primary hyperparathyroidism.
  • METHODS: We describe the clinical presentation, management, and outcome of a case of severe primary hyperparathyroidism manifesting with normocalcemia, likely attributable to the presence of asymptomatic CD.
  • Laboratory data (and reference ranges) were as follows: serum calcium, 2.34 mmol/L (2.1 to 2.6); phosphorus, 0.91 mmol/L (0.90 to 1.50); alkaline phosphatase, 421 U/L (40 to 135); albumin, 37 g/L (35 to 45); parathyroid hormone, 874 ng/L (15 to 65); urine calcium, 3.76 mmol/d (2.5 to 8); and 25-hydroxyvitamin D, <13 nmol/L (22 to 116).
  • The result of antibody screening for CD was highly positive, and a distal duodenal biopsy confirmed the diagnosis of CD.
  • A technetium Tc 99m sestamibi scan revealed uptake in the neck that was consistent with a single parathyroid adenoma, which was surgically removed.
  • CONCLUSION: Asymptomatic CD may be the underlying cause for some cases of normocalcemic primary hyperparathyroidism, and it should be considered in this setting.
  • [MeSH-major] Celiac Disease / complications. Celiac Disease / diagnosis. Hyperparathyroidism, Primary / diagnosis. Hyperparathyroidism, Primary / etiology
  • [MeSH-minor] Adult. Calcium / blood. Diagnosis, Differential. Female. Fractures, Bone / diagnosis. Fractures, Bone / etiology. Humans. Severity of Illness Index. Vitamin D Deficiency / complications. Vitamin D Deficiency / diagnosis

  • Genetic Alliance. consumer health - Celiac Disease.
  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • MedlinePlus Health Information. consumer health - Celiac Disease.
  • Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18463042.001).
  • [ISSN] 1934-2403
  • [Journal-full-title] Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
  • [ISO-abbreviation] Endocr Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] SY7Q814VUP / Calcium
  •  go-up   go-down


90. Newman EM, Bouvet M, Borgehi S, Herold DA, Deftos LJ: Causes of hypercalcemia in a population of military veterans in the United States. Endocr Pract; 2006 Sep-Oct;12(5):535-41
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Of the 212 patients, 59 (28%) had a diagnosis of malignant disease, 38 (18%) had primary hyperparathyroidism, and 114 (54%) had hypercalcemia due to a range of other causes.
  • A single parathyroid adenoma (in 20 of 22 patients who underwent surgical intervention) accounted for the majority of cases of primary hyperparathyroidism.
  • Although the 2 most common causes of hypercalcemia, hyperparathyroidism and malignant disease, were represented in this study, the majority of cases of hypercalcemia in this population of US veterans related to other etiologic factors.
  • [MeSH-minor] Acute Kidney Injury / complications. Acute Kidney Injury / diagnosis. Adult. Aged. Aged, 80 and over. Blood Urea Nitrogen. Calcitonin / blood. Calcitriol / blood. Calcium / blood. Calcium / urine. Creatinine / urine. Dehydration / complications. Female. Follow-Up Studies. Humans. Hyperparathyroidism / complications. Hyperparathyroidism / diagnosis. Male. Middle Aged. Neoplasms / complications. Neoplasms / diagnosis. Parathyroid Hormone / blood. Phosphorus / blood. Retrospective Studies. Sodium / blood. United States / epidemiology

  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. 1,25-DIHYDROXYCHOLECALCIFEROL .
  • Hazardous Substances Data Bank. SODIUM .
  • Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .
  • Hazardous Substances Data Bank. PHOSPHORUS, ELEMENTAL .
  • Hazardous Substances Data Bank. Calcitonin .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17002928.001).
  • [ISSN] 1934-2403
  • [Journal-full-title] Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
  • [ISO-abbreviation] Endocr Pract
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Parathyroid Hormone; 27YLU75U4W / Phosphorus; 9007-12-9 / Calcitonin; 9NEZ333N27 / Sodium; AYI8EX34EU / Creatinine; FXC9231JVH / Calcitriol; SY7Q814VUP / Calcium
  •  go-up   go-down


91. Ruggieri F, Chiesa A, Schorn K, Strobel K, Maggiorini M, Schmid C: Vanishing polyuria and respiratory failure. BMJ Case Rep; 2010;2010
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A large parathyroid adenoma was then removed.
  • [MeSH-major] Adenoma / diagnosis. Hypercalcemia / etiology. Multiple Organ Failure / etiology. Parathyroid Neoplasms / diagnosis. Polyuria / etiology. Respiratory Distress Syndrome, Adult / etiology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Nucl Med. 1996 Mar;37(3):469-71 [8772648.001]
  • [Cites] Intern Med. 1996 May;35(5):392-5 [8797054.001]
  • [Cites] Intensive Care Med. 1998 Mar;24(3):262-4 [9565811.001]
  • [Cites] J Endocrinol Invest. 2006 Jul-Aug;29(7):641-4 [16957413.001]
  • [Cites] Lancet. 2007 Aug 11;370(9586):468-70 [17693163.001]
  • (PMID = 22791497.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3028080
  •  go-up   go-down


92. Chadenat ML, Dalloz MA, D'Anglejean J, Fineyre F, Pico F: [Primary hyperparathyroidism as a differential diagnosis of Creutzfeldt-Jakob disease]. Rev Neurol (Paris); 2009 Feb;165(2):185-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary hyperparathyroidism as a differential diagnosis of Creutzfeldt-Jakob disease].
  • [Transliterated title] Hyperparathyroïdie primitive : un diagnostic différentiel de la maladie de Creutzfeldt-Jakob.
  • We report the case of a 79-years-old woman, hospitalized for a suspicion of Creutzfeldt-Jakob disease because of subacute dementia associated with gait disorder.
  • Laboratory testing revealed elevated serum calcium at 3.51 mmol/l (N=2.25-2.60 mmol/l) caused by a hyperparathyroidism.
  • After symptomatic treatment of hypercalcemia by biphosphonate, cognitive functions as well as the gait disorder improved quickly.
  • A double parathyroid adenoma was removed surgically.
  • Primary hyperparathyroidism is a curable cause of a Creutzfeldt-Jakob like syndrome.
  • [MeSH-major] Creutzfeldt-Jakob Syndrome / diagnosis. Hyperparathyroidism, Primary / etiology
  • [MeSH-minor] Aged. Calcium / blood. Dementia / etiology. Diagnosis, Differential. Electroencephalography. Female. Gait Apraxia / etiology. Humans. Hydrocephalus / etiology


93. Melton GB, Somervell H, Friedman KP, Zeiger MA, Cahid Civelek A: Interpretation of 99mTc sestamibi parathyroid SPECT scan is improved when read by the surgeon and nuclear medicine physician together. Nucl Med Commun; 2005 Jul;26(7):633-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Interpretation of 99mTc sestamibi parathyroid SPECT scan is improved when read by the surgeon and nuclear medicine physician together.
  • OBJECTIVE: Parathyroid gland localization and lateralization are important before surgery, particularly for minimally invasive parathyroidectomy (MIP) and recurrent hyperparathyroidism.
  • RESULTS: There were 120 patients with primary hyperparathyroidism (55 underwent MIP) and seven with secondary or tertiary hyperparathyroidism; seven patients had recurrent hyperparathyroidism.
  • Of 127 patients, 83 had single adenomas; 27, double adenomas; 15, hyperplasia; one, MENIIA; and one, parathyroid cancer.
  • The most common finding interpreted incorrectly by NMP alone and correctly by NMP+S was an ectopic superior parathyroid adenoma in the inferior position.
  • Ninety-eight per cent of patients were cured of their hyperparathyroidism.
  • CONCLUSIONS: Parathyroid sestamibi SPECT scan interpretation by an endocrine surgeon reading with a nuclear medicine attending resulted in improved accuracy of gland localization and lateralization compared to a nuclear medicine attending reading alone.
  • [MeSH-major] General Surgery. Hyperparathyroidism / radionuclide imaging. Image Enhancement / methods. Nuclear Medicine. Preoperative Care / methods. Technetium Tc 99m Sestamibi. Tomography, Emission-Computed, Single-Photon / methods

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15942484.001).
  • [ISSN] 0143-3636
  • [Journal-full-title] Nuclear medicine communications
  • [ISO-abbreviation] Nucl Med Commun
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


94. Spanu A, Schillaci O, Madeddu G: 99mTc labelled cationic lipophilic complexes in malignant and benign tumors: the role of SPET and pinhole-SPET in breast cancer, differentiated thyroid carcinoma and hyperparathyroidism. Q J Nucl Med Mol Imaging; 2005 Jun;49(2):145-69
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] 99mTc labelled cationic lipophilic complexes in malignant and benign tumors: the role of SPET and pinhole-SPET in breast cancer, differentiated thyroid carcinoma and hyperparathyroidism.
  • This review summarizes data on the employment of conventional SPET and P-SPET in breast cancer, differentiated thyroid cancer (DTC) and hyperparathyroidism patients, using the cationic lipophilic complexes [(99m)Tc]metoxy isobutyl isonitrile (sestaMIBI) and [(99m)Tc]tetrofosmin as oncotropic radiotracers.
  • In breast cancer patients, SPET with these radiotracers can play an important complementary role to planar scintimammography in detecting primary tumors, especially when non palpable and small in size, whereas SPET and particularly P-SPET represents the procedure of choice in preoperative axillary lymph node status evaluation in which planar is almost always irrelevant.
  • SPET can also be a useful complementary tool to planar parathyroid scintigraphy in the detection and localization of small and ectopic parathyroid adenomas in the neck or mediastinum, while neck P-SPET seems to also significantly increase planar sensitivity in hyperplastic glands.
  • SPET and P-SPET are indicated in persistent and recurrent hyperparathyroidism including from carcinoma.
  • [MeSH-major] Breast Neoplasms / radionuclide imaging. Hyperparathyroidism / radionuclide imaging. Technetium Compounds. Thyroid Neoplasms / radionuclide imaging. Tomography, Emission-Computed, Single-Photon / methods

  • Genetic Alliance. consumer health - Breast Cancer.
  • Genetic Alliance. consumer health - Thyroid Cancer.
  • MedlinePlus Health Information. consumer health - Breast Cancer.
  • MedlinePlus Health Information. consumer health - Thyroid Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16010252.001).
  • [ISSN] 1824-4785
  • [Journal-full-title] The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of Radiopharmaceutical Chemistry and Biology
  • [ISO-abbreviation] Q J Nucl Med Mol Imaging
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Cations; 0 / Radiopharmaceuticals; 0 / Technetium Compounds
  • [Number-of-references] 161
  •  go-up   go-down


95. Komanapalli CB, Cohen JI, Sukumar MS: Extended transcervical video-assisted thymectomy. Thorac Surg Clin; 2010 May;20(2):235-43
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The video-assisted extended approach is well suited for patients undergoing thymectomy for myasthenia gravis, thymic cysts, small thymoma, or mediastinal parathyroid adenoma.

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Published by Elsevier Inc.
  • (PMID = 20451134.001).
  • [ISSN] 1547-4127
  • [Journal-full-title] Thoracic surgery clinics
  • [ISO-abbreviation] Thorac Surg Clin
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


96. Manetti L, Grasso L, Vignali C, Petruzzi P, Lupi I, Genovesi M, Morselli LL, Cetani F, Acerbi G, Martino E: Undetectable inferior petrosal sinus levels of PTH-related peptide (PTHrP) in patients with ACTH-dependent Cushing's disease. J Endocrinol Invest; 2005 Oct;28(9):819-21
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PTH-related peptide (PTHrP), a member of the PTH family, is widely expressed in foetal and adult tissues, and it has been found in benign and malignant tumors, including GH and PRL-secreting adenomas.
  • In all patients, serum IPS and peripheral ACTH measurement were in keeping with the diagnosis of ACTH-dependent Cushing's disease.
  • [MeSH-major] Adrenocorticotropic Hormone / metabolism. Parathyroid Hormone-Related Protein / blood. Petrosal Sinus Sampling / methods. Pituitary ACTH Hypersecretion / blood

  • Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .
  • Hazardous Substances Data Bank. Corticotropin .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Clin Endocrinol (Oxf). 2002 Mar;56(3):419 [11940056.001]
  • [Cites] J Clin Endocrinol Metab. 1990 Nov;71(5):1112-8 [2229275.001]
  • [Cites] Miner Electrolyte Metab. 1995;21(1-3):148-51 [7565438.001]
  • [Cites] Annu Rev Physiol. 1998;60:431-60 [9558472.001]
  • [Cites] Clin Endocrinol (Oxf). 2001 Apr;54(4):555-7 [11318794.001]
  • [Cites] Annu Rev Med. 1994;45:189-200 [8198376.001]
  • [Cites] Endocrinology. 2003 Feb;144(2):407-11 [12538599.001]
  • [Cites] J Clin Pathol. 1993 Jul;46(7):682-3 [8157764.001]
  • [Cites] Endocr Rev. 1994 Feb;15(1):40-60 [8156938.001]
  • [Cites] J Clin Endocrinol Metab. 1995 Oct;80(10):3036-42 [7559893.001]
  • [Cites] J Endocrinol Invest. 2003;26(7 Suppl):64-73 [14604068.001]
  • [Cites] Endocr Rev. 1989 Nov;10(4):476-95 [2558877.001]
  • (PMID = 16370562.001).
  • [ISSN] 0391-4097
  • [Journal-full-title] Journal of endocrinological investigation
  • [ISO-abbreviation] J. Endocrinol. Invest.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Parathyroid Hormone-Related Protein; 9002-60-2 / Adrenocorticotropic Hormone; 9015-71-8 / Corticotropin-Releasing Hormone; SY7Q814VUP / Calcium
  •  go-up   go-down


97. Zhou G, Wei Y, Chen X, Jiang X, Gu W, Li X, Peng C, Ning G, Li H: Multiple endocrine neoplasia type 1 simultaneous with various types of enteropancreatic endocrine tumors: one case report: lessons learned. Pancreas; 2010 Jul;39(5):680-3
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Multiple endocrine neoplasia type 1 (MEN 1) is an autosomal dominant disorder characterized by the development of parathyroid hyperplasia, pancreatic endocrine tumors, pituitary adenomas, and adrenal adenomas.
  • [MeSH-major] Gastrinoma / surgery. Insulinoma / surgery. Multiple Endocrine Neoplasia Type 1 / surgery. Pancreatic Neoplasms / surgery. Parathyroid Neoplasms / surgery. Pituitary Neoplasms / surgery


98. Harimaya A, Tsubota H, Hoki K, Sato J, Kondo A, Yamada T, Seki N, Ikeda H, Himi T: Ossifying fibroma of the mandible with primary hyperparathyroidism due to non-familial parathyroid adenoma. J Laryngol Otol; 2007 Mar;121(3):281-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ossifying fibroma of the mandible with primary hyperparathyroidism due to non-familial parathyroid adenoma.
  • The neoplasm sometimes presents with hyperparathyroidism, most of which cases are due to familial parathyroid tumours.
  • We report a rare case of ossifying fibroma of the mandible which showed very rapid growth and presented with primary hyperparathyroidism due to non-familial parathyroid adenoma.
  • Despite improvement of parathyroid dysfunction after removal of the parathyroid adenoma, the tumour continued to grow very aggressively.
  • [MeSH-major] Adenoma / diagnosis. Fibroma, Ossifying / diagnosis. Hyperparathyroidism, Primary / etiology. Mandibular Neoplasms / diagnosis. Parathyroid Neoplasms / diagnosis
  • [MeSH-minor] Adult. Humans. Male. Neoplasms, Multiple Primary / diagnosis


99. Lindekleiv H, Due J: [Parathyroid surgery in Norway 1999-2005]. Tidsskr Nor Laegeforen; 2007 May 3;127(9):1181-4
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Parathyroid surgery in Norway 1999-2005].
  • BACKGROUND: A Norwegian study from 1994 reported large regional variations in the surgical treatment of hyperparathyroidism.
  • The aim of the present study was to describe regional variations in the frequency of surgery for hyperparathyroidism in Norway.
  • RESULTS: 29 hospitals performed 2,611 parathyroid operations during the six years assessed.
  • Two-thirds of the operated adenomas were not reported to the Norwegian Cancer Registry.
  • INTERPRETATION: Further studies are needed to explain the large increase and the regional variation in the number of operations for hyperparathyroidism.
  • Adenomas in the parathyroid glands should be exempted from the Norwegian cancer registration, as they do not represent pre-malignancy and are not reported consistently.
  • [MeSH-major] Hyperparathyroidism / surgery
  • [MeSH-minor] Adenoma / epidemiology. Adenoma / surgery. Adult. Aged. Aged, 80 and over. Humans. Middle Aged. Norway / epidemiology. Parathyroid Neoplasms / epidemiology. Parathyroid Neoplasms / surgery. Parathyroidectomy / statistics & numerical data. Practice Guidelines as Topic. Registries

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17479134.001).
  • [ISSN] 0807-7096
  • [Journal-full-title] Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række
  • [ISO-abbreviation] Tidsskr. Nor. Laegeforen.
  • [Language] nor
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Norway
  •  go-up   go-down


100. Goldfarb M, O'Neal P, Shih JL, Hartzband P, Connolly J, Hasselgren PO: Synchronous parathyroid carcinoma, parathyroid adenoma, and papillary thyroid carcinoma in a patient with severe and long-standing hyperparathyroidism. Endocr Pract; 2009 Jul-Aug;15(5):463-8
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Synchronous parathyroid carcinoma, parathyroid adenoma, and papillary thyroid carcinoma in a patient with severe and long-standing hyperparathyroidism.
  • OBJECTIVE: To describe a patient presenting with the rare constellation of synchronous parathyroid carcinoma, parathyroid adenoma, and papillary thyroid carcinoma.
  • RESULTS: The patient was a 59-year-old man who presented with severe clinical manifestations of long-standing primary hyperparathyroidism, a serum calcium concentration of 14.4 mg/dL, and a parathyroid hormone level of 2,023 pg/mL.
  • He was found to have a 3.4-cm parathyroid carcinoma on the left side and a 3.2-cm papillary carcinoma in the right thyroid lobe.
  • In addition, a 917-mg parathyroid adenoma was found on the right side.
  • CONCLUSION: Synchronous parathyroid and thyroid carcinomas are extremely rare.
  • To our knowledge, our patient is the first documented case with a parathyroid adenoma in addition to synchronous parathyroid and thyroid carcinomas.
  • The presence of concurrent parathyroid carcinoma and parathyroid adenoma can cause diagnostic confusion and should be considered in patients presenting with severe hyperparathyroidism.

  • Genetic Alliance. consumer health - Parathyroid carcinoma.
  • MedlinePlus Health Information. consumer health - Thyroid Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Ear Nose Throat J. 2002 Jun;81(6):395-8, 400-1 [12092283.001]
  • [Cites] Cancer. 2007 Jul 15;110(2):255-64 [17559137.001]
  • [Cites] J Clin Endocrinol Metab. 2001 Feb;86(2):485-93 [11157996.001]
  • [Cites] Surg Oncol. 1999 Nov;8(3):155-65 [11113666.001]
  • [Cites] Mayo Clin Proc. 2002 Aug;77(8):866-9 [12173721.001]
  • [Cites] Am J Otolaryngol. 2002 Nov-Dec;23(6):382-5 [12430133.001]
  • [Cites] Hum Pathol. 2003 Jan;34(1):54-64 [12605367.001]
  • [Cites] N Engl J Med. 2003 Oct 30;349(18):1722-9 [14585940.001]
  • [Cites] Cancer. 1973 Mar;31(3):600-5 [4693587.001]
  • [Cites] Nihon Gan Chiryo Gakkai Shi. 1979 Dec 20;14(7):1127-35 [541539.001]
  • [Cites] Br J Surg. 1988 Sep;75(9):873-4 [3179662.001]
  • [Cites] J Chin Med Assoc. 2005 Feb;68(2):87-91 [15759821.001]
  • [Cites] Br J Surg. 2005 Nov;92(11):1345-53 [16237743.001]
  • [Cites] Br J Surg. 2007 May;94(5):566-70 [17380564.001]
  • [Cites] J Endocrinol Invest. 2001 Jan;24(1):42-4 [11227731.001]
  • (PMID = 19491068.001).
  • [ISSN] 1934-2403
  • [Journal-full-title] Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
  • [ISO-abbreviation] Endocr Pract
  • [Language] ENG
  • [Grant] United States / NINR NIH HHS / NR / NR008545-06; United States / NINR NIH HHS / NR / R56 NR008545; United States / NINR NIH HHS / NR / R56 NR008545-06
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS217054; NLM/ PMC2917245
  •  go-up   go-down






Advertisement