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1. Lee SY, Hwang SS, Kim HJ, Jung JH: Eccrine acrospiroma of inguinal area: Computed tomography findings. J Comput Assist Tomogr; 2006 Mar-Apr;30(2):223-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Eccrine acrospiroma of inguinal area: Computed tomography findings.
  • Eccrine acrospiroma is a tumor originating from the sweat glands.
  • The computed tomography findings of eccrine acrospiroma in the right inguinal area are presented.
  • Eccrine acrospiroma should be considered in the differential diagnosis of a subcutaneous cystic mass with an internal solid nodule.
  • [MeSH-major] Acrospiroma / radiography. Sweat Gland Neoplasms / radiography. Tomography, X-Ray Computed

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  • (PMID = 16628036.001).
  • [ISSN] 0363-8715
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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2. Mebazaa A, Trabelsi S, Denguezli M, Sriha B, Belajouza C, Nouira R: Chondroid syringoma of the arm: an unusual localization. Dermatol Online J; 2006;12(1):14
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  • Chondroid syringoma (CS) is an uncommon, benign, sweat-gland tumor.
  • We present a case of a CS located in the right arm of a 43-year-old woman.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Arm. Sweat Gland Neoplasms / pathology

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  • (PMID = 16638382.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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3. Collman DR, Blasko M, Alonzo J, Stess R: Clear cell hidradenoma of the ankle. J Foot Ankle Surg; 2007 Sep-Oct;46(5):387-93
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  • [Title] Clear cell hidradenoma of the ankle.
  • Clear cell hidradenoma is a relatively common, benign eccrine neoplasm with rare presentations in the foot and ankle.
  • Variable clinical and histopathologic characteristics of the tumor warrant careful consideration over primary and recurrent malignancy, particularly eccrine carcinoma.
  • The first known case of primary benign clear cell hidradenoma of the ankle is presented with imaging studies, surgical management, and clinicopathologic correlation, distinguishing the neoplasm from its malignant counterparts.
  • [MeSH-major] Adenoma, Sweat Gland / diagnosis. Ankle / pathology. Foot Diseases / diagnosis. Sweat Gland Neoplasms / diagnosis

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  • (PMID = 17761324.001).
  • [ISSN] 1067-2516
  • [Journal-full-title] The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
  • [ISO-abbreviation] J Foot Ankle Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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4. Singh A, Sharma S, Verma S, Khanna A: Malignant nodular hidradenoma with angiolymphatic invasion: a case report. Indian J Pathol Microbiol; 2007 Jul;50(3):548-9
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  • [Title] Malignant nodular hidradenoma with angiolymphatic invasion: a case report.
  • Malignant nodular hidradenomas are rare variants of sweat gland carcinomas characterized by aggressive clinical behaviour.
  • [MeSH-major] Adenoma, Sweat Gland / diagnosis. Sweat Gland Neoplasms / diagnosis
  • [MeSH-minor] Aneuploidy. Humans. Lymph Nodes / pathology. Lymphatic Metastasis. Skin Neoplasms / secondary

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  • (PMID = 17883130.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
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5. Monteagudo B, Antón-Badiola IM, Muñoz MJ, Paredes-Suárez C, Vázquez-Blanco M: [Pigmented apocrine hidradenoma]. Actas Dermosifiliogr; 2005 Jan-Feb;96(1):50-1
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  • [Title] [Pigmented apocrine hidradenoma].
  • Apocrine hidradenoma is a benign adnexal neoplasm.
  • The same as other tumors of the sweat glands, there is a pigmented variety.
  • We present the case of a 92-year-old male who consulted his physician for a slow-growing asymptomatic lesion in the right groin which had been developing for 2 years.
  • After the histopathological study, the diagnosis was established as pigmented apocrine hidradenoma.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Hyperpigmentation / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 16476334.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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6. Turhan-Haktanir N, Sahin O, Bukulmez A, Demir Y: Chondroid syringoma in a child. Pediatr Dermatol; 2007 Sep-Oct;24(5):505-7
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  • Chondroid syringoma is a myxoid tumor of the skin, which has a reported incidence of <0.01% among primary skin tumors.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Nose Neoplasms / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 17958797.001).
  • [ISSN] 1525-1470
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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7. Beals TC, Nickisch F, Teman C, Florell SR, Layfield LJ: Chondroid syringoma: case report of a highly unusual foot tumor. Foot Ankle Int; 2010 Apr;31(4):333-5
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  • [Title] Chondroid syringoma: case report of a highly unusual foot tumor.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Adenoma, Pleomorphic / radiography. Sweat Gland Neoplasms / pathology. Sweat Gland Neoplasms / radiography

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  • (PMID = 20371021.001).
  • [ISSN] 1071-1007
  • [Journal-full-title] Foot & ankle international
  • [ISO-abbreviation] Foot Ankle Int
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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8. Gouiaa N, Abbes K, Fakhfekh I, Ayadi L, Bahri I, Chaari C, Ellouze S, Chtourou I, Makni S, Sellami-Boudawara T: [Hidradenocarcinoma arising from pre-existing hidradenoma]. Ann Dermatol Venereol; 2008 Oct;135(10):714-5
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  • [Title] [Hidradenocarcinoma arising from pre-existing hidradenoma].
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma, Sweat Gland / pathology. Cell Transformation, Neoplastic / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 18929928.001).
  • [ISSN] 0151-9638
  • [Journal-full-title] Annales de dermatologie et de vénéréologie
  • [ISO-abbreviation] Ann Dermatol Venereol
  • [Language] fre
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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9. Kazakov DV, Bisceglia M, Calonje E, Hantschke M, Kutzner H, Mentzel T, Michal M, Mukensnabl P, Spagnolo DV, Rütten A, Rose C, Urso C, Vazmitel M, Zelger B: Tubular adenoma and syringocystadenoma papilliferum: a reappraisal of their relationship. An interobserver study of a series, by a panel of dermatopathologists. Am J Dermatopathol; 2007 Jun;29(3):256-63
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  • [Title] Tubular adenoma and syringocystadenoma papilliferum: a reappraisal of their relationship. An interobserver study of a series, by a panel of dermatopathologists.
  • Tubular adenoma (TA) and syringocystadenoma papilliferum (SCAP) may show histopathological overlap, with some lesions having features of both neoplasms (SCAP + TA).
  • Four observers blindly assessed 67 cases of TA, SCAP, and their lookalikes (poroma, apocrine adenoma, apocrine carcinoma; all lesions focally featuring a pseudopapillary pattern), and classified the lesions into one of four categories:.
  • Lesions were also classified as benign or malignant.
  • All observers agreed that the lesions were benign; the only apocrine carcinoma included was recognized as such by all observers.
  • [MeSH-major] Adenoma, Sweat Gland / diagnosis. Cystadenoma / diagnosis. Neoplasms, Multiple Primary / diagnosis. Sweat Gland Neoplasms / diagnosis

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  • (PMID = 17519623.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
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10. Gönül M, Soylu S, Gül U, Kaya I, Albayrak L, Unal T: Linear syringocystadenoma papilliferum of the arm: a rare localization of an uncommon tumour. Acta Derm Venereol; 2008;88(5):528-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 18779904.001).
  • [ISSN] 0001-5555
  • [Journal-full-title] Acta dermato-venereologica
  • [ISO-abbreviation] Acta Derm. Venereol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Sweden
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11. Schadt CR, Boyd AS: Eccrine syringofibroadenoma with co-existent squamous cell carcinoma. J Cutan Pathol; 2007 Dec;34 Suppl 1:71-4
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  • [Title] Eccrine syringofibroadenoma with co-existent squamous cell carcinoma.
  • Eccrine syringofibroadenoma (ESFA) is a rare, benign adnexal tumor arising most often on the extremities of elderly individuals.
  • The cords contain scattered ductal structures lined with cuboidal cells resembling eccrine ducts.
  • The co-existence of ESFA with squamous cell carcinoma has been described, eliciting the term eccrine syringofibroadenoma.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Carcinoma, Squamous Cell / pathology. Eccrine Glands / pathology. Fibroadenoma / pathology. Neoplasms, Multiple Primary / pathology. Sweat Gland Neoplasms / pathology
  • [MeSH-minor] Acanthoma / diagnosis. Acrospiroma / diagnosis. Adenocarcinoma / diagnosis. Diagnosis, Differential. Female. Humans. Middle Aged. Neoplasms, Fibroepithelial / diagnosis

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  • (PMID = 17997744.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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12. Yavel R, Hinshaw M, Rao V, Hartig GK, Harari PM, Stewart D, Snow SN: Hidradenomas and a hidradenocarcinoma of the scalp managed using Mohs micrographic surgery and a multidisciplinary approach: case reports and review of the literature. Dermatol Surg; 2009 Feb;35(2):273-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Adenoma, Sweat Gland / surgery. Head and Neck Neoplasms / pathology. Head and Neck Neoplasms / surgery. Scalp / surgery. Sweat Gland Neoplasms / pathology. Sweat Gland Neoplasms / surgery

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  • (PMID = 19215270.001).
  • [ISSN] 1524-4725
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 36
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13. Barker-Griffith AE, Streeten BW, Charles NC: Moll gland neoplasms of the eyelid: a clinical and pathological spectrum in 5 cases. Arch Ophthalmol; 2006 Nov;124(11):1645-9
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  • [Title] Moll gland neoplasms of the eyelid: a clinical and pathological spectrum in 5 cases.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Apocrine Glands / pathology. Eyelid Neoplasms / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 17102015.001).
  • [ISSN] 0003-9950
  • [Journal-full-title] Archives of ophthalmology (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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14. El-Naggar AK: Clear cell hidradenoma of the skin--a third tumor type with a t(11;19)-associated TORC1-MAML2 gene fusion: Genes Chromosomes Cancer. 2005;43:202-205. Adv Anat Pathol; 2006 Mar;13(2):80-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clear cell hidradenoma of the skin--a third tumor type with a t(11;19)-associated TORC1-MAML2 gene fusion: Genes Chromosomes Cancer. 2005;43:202-205.
  • [MeSH-major] Adenoma, Sweat Gland / genetics. DNA-Binding Proteins / genetics. Nuclear Proteins / genetics. Sweat Gland Neoplasms / genetics. Transcription Factors / genetics. Translocation, Genetic

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  • (PMID = 16670462.001).
  • [ISSN] 1072-4109
  • [Journal-full-title] Advances in anatomic pathology
  • [ISO-abbreviation] Adv Anat Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CRTC1 protein, human; 0 / DNA-Binding Proteins; 0 / MAML2 protein, human; 0 / Nuclear Proteins; 0 / Transcription Factors
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15. Qiu RX, Gu LL, Zhang Q: [A case of nasal adenoma apocrine]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2008 Dec;43(12):959-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of nasal adenoma apocrine].
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Nose Neoplasms / pathology

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  • (PMID = 19141253.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
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16. Smiri KH, Fenniche S, Marrak H, Daoud L, Debbiche A, Ben Ayed M, Mokhtar I: [Chondroid syringoma]. Tunis Med; 2005 Jun;83(6):372-4
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  • All patients presented with a single painless skin lesion of about 1,5 cm on the face, lasting for 14 months on average.
  • Chondroid syringoma is a benign sweat gland tumor.
  • This lesion is electively located in the craniofacial area, made of a subcutaneous painless tumor measuring from 0.5 to 3 cm.
  • Diagnosis can always be confirmed by histology which shows tubuloalveolar and gland like structures with two or more cuboidal cell lines in a fibroadipoid or chondroid stroma that is positively stained for Alcian blue.
  • [MeSH-major] Adenoma, Pleomorphic / surgery. Salivary Gland Neoplasms / surgery
  • [MeSH-minor] Adult. Disease Progression. Humans. Male. Middle Aged. Patient Satisfaction. Prognosis. Retrospective Studies. Treatment Outcome

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  • (PMID = 16156416.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Tunisia
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17. Nemoto N, Suzukawa K, Shimizu S, Shinagawa A, Takei N, Taki T, Hayashi Y, Kojima H, Kawakami Y, Nagasawa T: Identification of a novel fusion gene MLL-MAML2 in secondary acute myelogenous leukemia and myelodysplastic syndrome with inv(11)(q21q23). Genes Chromosomes Cancer; 2007 Sep;46(9):813-9
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  • [Title] Identification of a novel fusion gene MLL-MAML2 in secondary acute myelogenous leukemia and myelodysplastic syndrome with inv(11)(q21q23).
  • The inv(11)(q21q23) results in the creation of a chimeric RNA encoding a putative fusion protein containing 1,408 amino acids from the NH2-terminal part of MLL and 952 amino acids from the COOH-terminal part of MAML2.
  • MLL-MAML2 in secondary AML/MDS and MECT1-MAML2 in mucoepithelioid carcinoma, benign Wartin's tumor, and clear cell hidradenoma consist of the same COOH-terminal part of MAML2.


18. Kazakov DV, Vanecek T, Belousova IE, Mukensnabl P, Kollertova D, Michal M: Skin-type hidradenoma of the breast parenchyma with t(11;19) translocation: hidradenoma of the breast. Am J Dermatopathol; 2007 Oct;29(5):457-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Skin-type hidradenoma of the breast parenchyma with t(11;19) translocation: hidradenoma of the breast.
  • Skin adnexal type tumors situated in the parenchyma of the breast are very rare.
  • We report herein a case of solid-cystic hidradenoma of the breast.
  • The tumor was situated in the parenchyma of the breast of a 55-year-old female and showed no connection to the overlying skin on ultrasound and radiology investigations, grossly and microscopically.
  • This t(11;19) translocation has been reported in approximately 50% of hidradenomas of the skin.
  • [MeSH-major] Adenoma, Sweat Gland / genetics. Breast Neoplasms / genetics. Chromosomes, Human, Pair 11. Chromosomes, Human, Pair 19. Translocation, Genetic / genetics

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  • (PMID = 17890914.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / MECT1-MAML2 fusion protein, human; 0 / Oncogene Proteins, Fusion
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19. Agrawal A, Kumar A, Sinha AK, Kumar B, Sabira KC: Chondroid syringoma. Singapore Med J; 2008 Feb;49(2):e33-4
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  • Pleomorphic adenoma, or chondroid syringoma (CS), is a rare, benign, skin appendageal tumour.
  • We present a case of a CS located over the forehead of a 32-year-old man.
  • In the evaluation of a middle-aged male patient with a small cutaneous nodule in the head and neck region, chondroid syringoma should also be considered in the differential diagnosis.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Forehead / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 18301822.001).
  • [ISSN] 0037-5675
  • [Journal-full-title] Singapore medical journal
  • [ISO-abbreviation] Singapore Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
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20. Gatti A, di Meo N, Trevisan G: Dermoscopy of eccrine acrospiroma masquerading as nodular malignant melanoma. Acta Dermatovenerol Alp Pannonica Adriat; 2010 Dec;19(4):23-5
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  • [Title] Dermoscopy of eccrine acrospiroma masquerading as nodular malignant melanoma.
  • Eccrine acrospiroma, better known as eccrine poroma, is a benign adnexal neoplasm of the skin.
  • [MeSH-major] Acrospiroma / pathology. Dermoscopy. Melanoma / pathology. Skin Neoplasms / pathology. Sweat Gland Neoplasms / pathology


21. Bollée G, Patey N, Cazajous G, Robert C, Goujon JM, Fakhouri F, Bruneval P, Noël LH, Knebelmann B: Thrombotic microangiopathy secondary to VEGF pathway inhibition by sunitinib. Nephrol Dial Transplant; 2009 Feb;24(2):682-5
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  • A 44-year-old woman with a history of malignant skin hidradenoma was started on sunitinib for refractory disease.
  • [MeSH-minor] Adenoma, Sweat Gland / drug therapy. Adult. Antineoplastic Agents / adverse effects. Female. Humans. Protein Kinase Inhibitors / adverse effects. Skin Neoplasms / drug therapy

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  • [CommentIn] Nephrol Dial Transplant. 2009 Jun;24(6):2002-3 [19332867.001]
  • (PMID = 19054798.001).
  • [ISSN] 1460-2385
  • [Journal-full-title] Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
  • [ISO-abbreviation] Nephrol. Dial. Transplant.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Indoles; 0 / Protein Kinase Inhibitors; 0 / Pyrroles; 0 / VEGFA protein, human; 0 / Vascular Endothelial Growth Factor A; 0 / sunitinib
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22. Ryu JK, Jin W, Kim GY, Lee JH: Sonographic and magnetic resonance imaging findings of a chondroid syringoma of the heel: case report and literature review. J Ultrasound Med; 2007 Oct;26(10):1435-9
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  • [Title] Sonographic and magnetic resonance imaging findings of a chondroid syringoma of the heel: case report and literature review.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Foot. Magnetic Resonance Imaging. Sweat Gland Neoplasms / diagnosis

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  • (PMID = 17901146.001).
  • [ISSN] 0278-4297
  • [Journal-full-title] Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
  • [ISO-abbreviation] J Ultrasound Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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23. Knoedler D, Susnik B, Gonyo MB, Osipov V: Giant apocrine hidradenoma of the breast. Breast J; 2007 Jan-Feb;13(1):91-3
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  • [Title] Giant apocrine hidradenoma of the breast.
  • We report a case of a 26-year-old woman with an 8.0-cm tumor of the left breast.
  • The pathologic evaluation of the core biopsy and the subsequent excision specimen revealed a benign sclerosing, cystic, and papillary adnexal tumor with apocrine and clear cell morphology.
  • The final diagnosis was apocrine hidradenoma.
  • [MeSH-major] Adenoma, Sweat Gland / diagnosis. Breast Neoplasms / diagnosis. Sweat Gland Neoplasms / diagnosis

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  • (PMID = 17214802.001).
  • [ISSN] 1075-122X
  • [Journal-full-title] The breast journal
  • [ISO-abbreviation] Breast J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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24. Novak NP, Kaić G, Tomasović-Loncarić C, Zic R, Skoro M, Ostović KT: Fine-needle aspiration cytology of apocrine hidradenoma. Coll Antropol; 2010 Jun;34(2):671-4
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  • [Title] Fine-needle aspiration cytology of apocrine hidradenoma.
  • An apocrine hidradenoma is a benign adnexal neoplasm, usually covered by intact skin, but may show superficial ulceration and serous discharge.
  • We described cytomorphologic features of cutaneous nodule that might be a lead to the cytologic diagnosis of hidradenoma, but primary or secondary malignant tumour has been ruled out first.
  • [MeSH-major] Acrospiroma / pathology. Sweat Gland Neoplasms / pathology
  • [MeSH-minor] Aged. Biopsy, Fine-Needle. Diagnosis, Differential. Humans. Male. Skin Neoplasms / pathology. Skin Neoplasms / surgery

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  • (PMID = 20698151.001).
  • [ISSN] 0350-6134
  • [Journal-full-title] Collegium antropologicum
  • [ISO-abbreviation] Coll Antropol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Croatia
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25. Sington J, Chandrapala R, Manek S, Hollowood K: Mitotic count is not predictive of clinical behavior in hidradenoma papilliferum of the vulva: a clinicopathologic study of 19 cases. Am J Dermatopathol; 2006 Aug;28(4):322-6
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  • [Title] Mitotic count is not predictive of clinical behavior in hidradenoma papilliferum of the vulva: a clinicopathologic study of 19 cases.
  • Although it is generally recognized that some benign sweat gland neoplasms may show appreciable mitotic activity, there are few reports of its quantitative analysis in specific tumor types or of its correlation with clinical behavior.
  • The presence of a large number of mitoses in a sweat gland tumor for which the histologic criteria of malignancy are not well defined, particularly in association with nuclear abnormalities, may produce a considerable diagnostic challenge.
  • We recently encountered such a problem in a putative case of hidradenoma papilliferum.
  • Therefore, we have undertaken a retrospective clinicopathologic study of 19 cases originally diagnosed as hidradenoma papilliferum or probable hidradenoma papilliferum, with a particular emphasis on the relationship of the mitotic index to clinical behavior.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Mitosis. Vulvar Diseases / pathology

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  • (PMID = 16871035.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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26. Petersson F, Kutzner H, Spagnolo DV, Bisceglia M, Kacerovska D, Vazmitel M, Michal M, Kazakov DV: Adenoid cystic carcinoma-like pattern in spiradenoma and spiradenocylindroma: a rare feature in sporadic neoplasms and those associated with Brooke-Spiegler syndrome. Am J Dermatopathol; 2009 Oct;31(7):642-8
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  • Spiradenoma is a benign, morphologically well-defined cutaneous adnexal neoplasm that is closely related to cylindroma.
  • The ACC-like areas were typified by cribriform formations of epithelial cells concentrically arranged around gland-like spaces filled with mucin, homogeneous eosinophilic material, or granular basophilic material.
  • It is concluded that the ACC-like pattern, although a rare feature and of no clinical consequence, is a distinctive finding in a minority of cases and extends the morphological spectrum of spiradenoma and spiradenocylindroma occurring sporadically or in the setting of Brooke-Spiegler syndrome.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Carcinoma, Adenoid Cystic / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 19633533.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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27. Angulo J, González-Guerra E, Vargas-Machuca I, Fariña MC, Martín L, Requena L: [Multiple linear spiradenoma with a linear distribution]. Actas Dermosifiliogr; 2006 Jan-Feb;97(1):31-4
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  • We report the case of a 32-year old woman who presented with multiple nodules in the left arm and breast that had been present for 15 years.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 16540048.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 18
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28. Mellanby RJ, Craig R, Evans H, Herrtage ME: Plasma concentrations of parathyroid hormone-related protein in dogs with potential disorders of calcium metabolism. Vet Rec; 2006 Dec 16;159(25):833-8
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  • The plasma concentrations of total calcium, ionised calcium, albumin, parathyroid hormone and parathyroid hormone-related protein (PTHrp) were measured in 25 dogs with lymphoma, nine dogs with primary hyperparathyroidism and seven dogs with adenocarcinoma of the apocrine gland of the anal sac.
  • The concentration of PTHrp was high in 12 of the 14 dogs that were hypercalcaemic because of an underlying malignancy but was within the reference range in all the control dogs, in the 17 normocalcaemic dogs with lymphoma and in the seven dogs which were hypercalcaemic because of a parathyroid adenoma.
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / veterinary. Anal Sacs. Animals. Case-Control Studies. Dogs. Hyperparathyroidism / diagnosis. Hyperparathyroidism / veterinary. Lymphoma / diagnosis. Lymphoma / veterinary. Predictive Value of Tests. Sensitivity and Specificity. Sweat Gland Neoplasms / diagnosis. Sweat Gland Neoplasms / veterinary

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  • (PMID = 17172477.001).
  • [ISSN] 0042-4900
  • [Journal-full-title] The Veterinary record
  • [ISO-abbreviation] Vet. Rec.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Parathyroid Hormone-Related Protein
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29. Teschner M, Buhr T, Donnerstag F, Lenarz T, Majdani O: [Expansion of an ceruminous adenoma into the middle ear]. Laryngorhinootologie; 2006 Jun;85(6):444-7
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  • [Title] [Expansion of an ceruminous adenoma into the middle ear].
  • Pathohistology revealed a ceruminal gland adenoma.
  • They are a rare phenomenon and should be distinguished from middle ear adenomas, pleomorph ceruminal gland adenomas, ceruminal gland adenocarcinomas and cylindromas of the ceruminal glands.
  • Despite its rare occurrence, a ceruminal gland adenoma must be taken into consideration in the differential diagnosis of individual cholesteatoma cases.
  • [MeSH-major] Adenoma / diagnosis. Apocrine Glands / pathology. Carcinoma, Squamous Cell / diagnosis. Cerumen. Ear Canal / pathology. Ear Neoplasms / diagnosis. Ear, Middle / pathology. Sweat Gland Neoplasms / diagnosis

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  • (PMID = 16770841.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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30. Toulemonde A, Croue A, Rodien P, Verret JL: [Malignant nodular hidradenoma and multiple nodular hidradenomas in a hypogonadic patient]. Ann Dermatol Venereol; 2006 Dec;133(12):1005-8
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  • [Title] [Malignant nodular hidradenoma and multiple nodular hidradenomas in a hypogonadic patient].
  • BACKGROUND: We report a case of multiple benign nodular hidradenomas associated with malignant nodular hidradenoma in a hypogonadic patient.
  • CASE-REPORT: A 49 year-old man presented 11 benign nodular hidradenomas in the pectoral region.
  • A malignant nodular hidradenoma had recently appeared in this region some distance from the pre-existing benign modular hidradenomas.
  • Large numbers of estrogen receptors were demonstrated in each of the benign nodular hidradenomas.
  • The malignant nodular hidradenoma mass was unavailable and screening for these receptors was not possible.
  • DISCUSSION: Cases of multiple nodular hidradenoma are extremely rare: we have seen only two.
  • To the best of our knowledge, there have been no reports to date of combined malignant nodular hidradenoma and multiple benign nodular hidradenoma.
  • However, the presence of estrogen receptors has occasionally been demonstrated in benign nodular hidradenomas.
  • Our patient's endocrine disease may have played a role in the presentation of multiple hidradenomas, but this cannot be demonstrated.
  • [MeSH-major] Adenoma, Sweat Gland / complications. Hypogonadism / complications. Sweat Gland Neoplasms / complications

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  • (PMID = 17185934.001).
  • [ISSN] 0151-9638
  • [Journal-full-title] Annales de dermatologie et de vénéréologie
  • [ISO-abbreviation] Ann Dermatol Venereol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Receptors, Estrogen
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31. Sivamani R, Wadhera A, Craig E: Chondroid syringoma: case report and review of the literature. Dermatol Online J; 2006;12(5):8
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  • Chondroid syringoma is a rare mixed tumor of the skin that was first described by Hirsch and Helwig.
  • Characteristically, it is composed of a proliferation of epithelial cells set in a myxoid and chondroid matrix.
  • Although chondroid syringomas are predominantly benign, malignant forms have been reported.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Facial Neoplasms / pathology. Neoplasm Recurrence, Local / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 16962023.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 24
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32. Rodríguez-Martín M, Sánchez González R, Sáez-Rodríguez M, García-Bustínduy M, Martín-Herrera A, Noda-Cabrera A: An unusual case of congenital linear eccrine spiradenoma. Pediatr Dermatol; 2009 Mar-Apr;26(2):180-3
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  • [Title] An unusual case of congenital linear eccrine spiradenoma.
  • Eccrine spiradenoma (ES) is a benign uncommon tumor of skin adnexa with a characteristic clinical and histopathological presentation.
  • [MeSH-major] Adenoma, Sweat Gland / congenital. Eccrine Glands / pathology. Neoplasms, Multiple Primary / congenital. Sweat Gland Neoplasms / congenital

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  • (PMID = 19419467.001).
  • [ISSN] 1525-1470
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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33. Page RN, Dittrich L, King R, Boulos F, Page DL: Syringomatous adenoma of the nipple occurring within a supernumerary breast: a case report. J Cutan Pathol; 2009 Nov;36(11):1206-9
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  • [Title] Syringomatous adenoma of the nipple occurring within a supernumerary breast: a case report.
  • Originally described by Rosen in 1983, syringomatous nipple adenoma (SAN) is a tumor of disputed histogenesis, which can be problematic both diagnostically and therapeutically.
  • It is a benign primary tumor of breast epithelium with histology similar to that of the syringoma.
  • This case represents, to our knowledge, the first such reported case, and represents a significant finding as its presence could lend some confusion as to whether or not this represents a benign primary process of breast or a potentially infiltrative tumor of the skin.
  • [MeSH-major] Adenoma / pathology. Breast Neoplasms / pathology. Nipples / pathology. Sweat Gland Neoplasms / pathology. Syringoma / pathology

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  • (PMID = 19469876.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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34. Mathiasen RA, Rasgon BM, Rumore G: Malignant chondroid syringoma of the face: a first reported case. Otolaryngol Head Neck Surg; 2005 Aug;133(2):305-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Facial Neoplasms / pathology. Neoplasm Invasiveness / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Biopsy, Needle. Dermatology / methods. Female. Follow-Up Studies. Humans. Immunohistochemistry. Middle Aged. Neoplasm Staging. Rare Diseases. Risk Assessment. Sweat Gland Neoplasms / pathology. Sweat Gland Neoplasms / surgery. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 16087034.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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35. Kakitsubata Y, Theodorou SJ, Theodorou DJ, Nakahara M, Yuki Y, Yokouchi T: Giant chondroid syringoma presenting as a growing subcutaneous mass in the upper arm: MRI findings with pathologic correlation. Joint Bone Spine; 2009 Dec;76(6):711-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Chondroid syringoma of skin is a rare type of soft tissue tumor originating from the sweat glands.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Magnetic Resonance Imaging / methods. Sweat Gland Neoplasms / diagnosis

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  • (PMID = 19793672.001).
  • [ISSN] 1778-7254
  • [Journal-full-title] Joint, bone, spine : revue du rhumatisme
  • [ISO-abbreviation] Joint Bone Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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36. Stokes J, Ironside J, Smith C, Dhillon B: Tubular apocrine adenoma--an unusual eyelid tumour. Eye (Lond); 2005 Feb;19(2):237-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tubular apocrine adenoma--an unusual eyelid tumour.
  • [MeSH-major] Adenoma / pathology. Eyelid Neoplasms / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 15105822.001).
  • [ISSN] 0950-222X
  • [Journal-full-title] Eye (London, England)
  • [ISO-abbreviation] Eye (Lond)
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
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37. Magliulo G, Bertin S: Adenoma of the ceruminous gland. Otolaryngol Head Neck Surg; 2010 Sep;143(3):459-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenoma of the ceruminous gland.
  • [MeSH-major] Adenoma / pathology. Cerumen. Ear Canal. Ear Neoplasms / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 20723789.001).
  • [ISSN] 1097-6817
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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38. MacNeill KN, Riddell RH, Ghazarian D: Perianal apocrine adenocarcinoma arising in a benign apocrine adenoma; first case report and review of the literature. J Clin Pathol; 2005 Feb;58(2):217-9
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  • [Title] Perianal apocrine adenocarcinoma arising in a benign apocrine adenoma; first case report and review of the literature.
  • Benign apocrine lesions have been described in the anogenital region, although according to the World Health Organisation convincing examples of anal apocrine adenocarcinomas have not been published.
  • This report describes the case of an invasive apocrine adenocarcinoma arising in a benign adenoma in the perianal region of a 45 year old woman.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma, Sweat Gland / pathology. Anus Neoplasms / pathology. Apocrine Glands / pathology. Sweat Gland Neoplasms / pathology


39. Martinelli PT, Cohen PR, Schulze KE, Tschen JA, Nelson BR: Mohs micrographic surgery for tubular apocrine adenoma. Int J Dermatol; 2006 Nov;45(11):1377-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mohs micrographic surgery for tubular apocrine adenoma.
  • [MeSH-major] Adenoma, Sweat Gland / surgery. Apocrine Glands / surgery. Mohs Surgery. Sweat Gland Neoplasms / surgery

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  • (PMID = 17076735.001).
  • [ISSN] 0011-9059
  • [Journal-full-title] International journal of dermatology
  • [ISO-abbreviation] Int. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
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40. Yamamoto T, Mamada A: Syringocystadenoma papilliferum arising on the thigh without connection to the overlying epidermis. Am J Dermatopathol; 2008 Feb;30(1):84-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Epidermis / pathology. Sweat Gland Neoplasms / pathology. Thigh / pathology

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  • (PMID = 18212554.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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41. Bumgardner AC, Hsu S, Nunez-Gussman JK, Schwartz MR: Trichoepitheliomas and eccrine spiradenomas with spiradenoma/cylindroma overlap. Int J Dermatol; 2005 May;44(5):415-7
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  • [Title] Trichoepitheliomas and eccrine spiradenomas with spiradenoma/cylindroma overlap.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Carcinoma, Adenoid Cystic / pathology. Neoplasms, Basal Cell / pathology. Neoplasms, Multiple Primary / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 15869542.001).
  • [ISSN] 0011-9059
  • [Journal-full-title] International journal of dermatology
  • [ISO-abbreviation] Int. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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42. Brewer NH, Bridges MA: Chondroid syringoma of the nasal soft tissue triangle. Otolaryngol Head Neck Surg; 2009 Apr;140(4):606-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Nose Neoplasms / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 19328357.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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43. Arias D, Castellano VM, Córdoba S, Miñano R, Martínez D, Borbujo JM: [Atypical presentation of syringocystoadenoma papilliferum]. Actas Dermosifiliogr; 2006 Dec;97(10):647-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Siringocistoadenoma papilífero de presentación atípica.
  • Syringocystoadenoma papilliferum is benign adnexal tumor derived from the sweat glands that is located in the head and neck in 70-80% of patients, and commonly presents as a papule or a solitary nodule.
  • [MeSH-major] Adenoma, Sweat Gland / diagnosis. Neoplasms, Second Primary / diagnosis. Sweat Gland Neoplasms / diagnosis

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  • (PMID = 17173827.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 18
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44. Akcay EK, Simsek S, Cagil N, Belenli O, Gumus M: Apocrine adenocarcinoma of the right eyelid and apocrine adenoma of the left maxillary sinus. Can J Ophthalmol; 2008 Oct;43(5):609-10
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  • [Title] Apocrine adenocarcinoma of the right eyelid and apocrine adenoma of the left maxillary sinus.

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  • (PMID = 18982051.001).
  • [ISSN] 0008-4182
  • [Journal-full-title] Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
  • [ISO-abbreviation] Can. J. Ophthalmol.
  • [Language] ENG
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
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45. Kazakov DV, Grossmann P, Spagnolo DV, Vanecek T, Vazmitel M, Kacerovska D, Zelger B, Calonje E, Michal M: Expression of p53 and TP53 mutational analysis in malignant neoplasms arising in preexisting spiradenoma, cylindroma, and spiradenocylindroma, sporadic or associated with Brooke-Spiegler syndrome. Am J Dermatopathol; 2010 May;32(3):215-21
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  • We performed immunohistochemical assessment of p53 expression and TP53 mutational analysis of 15 malignant neoplasms arising from preexisting benign cylindroma, spiradenoma, and spiradenocylindroma, sporadic or associated with Brooke-Spiegler syndrome.
  • None of the 12 benign control group cases harbored a TP53 mutation, whereas all 12 demonstrated single nucleotide polymorphisms identical to those detected in the malignant tumor group.
  • In conclusion, we found a fairly high rate of p53 expression in malignant neoplasms arising from preexisting benign spiradenomas, cylindromas, and spiradenocylindromas.
  • Whereas immunostaining for p53 has been suggested as an adjunct tool to differentiate benign spiradenoma, cylindroma, and spiradenocylindroma from their malignant counterparts, its utility is limited by its heterogeneous pattern of expression, especially the sometimes lack of staining in clearly malignant areas and the occurrence of focal, weak positivity in the benign residua or in unequivocally benign neoplasms.
  • [MeSH-major] Adenoma / genetics. Carcinoma, Adenoid Cystic / genetics. Neoplasms, Multiple Primary / genetics. Point Mutation. Sweat Gland Neoplasms / genetics. Tumor Suppressor Protein p53 / genetics

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  • (PMID = 20075707.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm; 0 / TP53 protein, human; 0 / Tumor Suppressor Protein p53
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46. Tronnier M, Vogelbruch M: Atypical fibroxanthoma arising in an area of syringocystadenoma papilliferum associated with nevus sebaceus: positivity of the atypical fibroxanthoma component for CD31. J Cutan Pathol; 2007 Dec;34 Suppl 1:58-63
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Cystadenoma / pathology. Hamartoma / pathology. Sweat Gland Neoplasms / pathology. Xanthomatosis / pathology

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  • (PMID = 17997741.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD31; 0 / Biomarkers, Tumor
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47. Premalata CS, Kumar RV, Malathi M, Shenoy AM, Nanjundappa N: Cutaneous leiomyosarcoma, trichoblastoma, and syringocystadenoma papilliferum arising from nevus sebaceus. Int J Dermatol; 2007 Mar;46(3):306-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • X-Ray of the skull was normal and no evidence of metastatic disease was identified.
  • The specimen of the initial surgery consisted of skin-covered tissue with an exophytic firm growth measuring 6 x 5 x 4 cm.
  • The skin surface was rough with areas of ulceration.
  • The third lesion was a spindle cell sarcoma which formed the major part of the lesion, diffusely infiltrating the dermis and subcutaneous tissue, elevating and ulcerating the overlying skin.
  • The tumor cells were seen encircling the sweat glands, without destroying them (Fig. 3).
  • A small area of epidermal hyperplasia with acanthosis and papillomatosis overlying malformed highly placed sebaceous glands was the only evidence of a pre-existing nevus sebaceus.
  • The wide excision specimen of the recurrent swelling consisted of a skin-covered nodule with ulceration, measuring 3 x 4 x 3 cm, with a gray-white whorled cut surface.
  • Multiple sections showed only spindle cell sarcoma infiltrating the skin and subcutaneous tissue, morphologically similar to the earlier tumor, with ulceration of the overlying skin.
  • The patient received postoperative radiotherapy and is disease free 8 months after diagnosis.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Head and Neck Neoplasms / pathology. Leiomyosarcoma / pathology. Neoplasms, Multiple Primary / pathology. Nevus / pathology. Scalp. Skin Neoplasms / pathology. Sweat Gland Neoplasms / pathology


48. El Demellawy D, Daya D, Alowami S: Clear cell hidradenoma: an unusual vulvar tumor. Int J Gynecol Pathol; 2008 Jul;27(3):457-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clear cell hidradenoma: an unusual vulvar tumor.
  • Clear cell hidradenoma (CCH) is a benign skin appendageal tumor.
  • Most cases occur in the skin of the head and face.
  • Although most cases are benign, occasional cases with malignant transformation have been reported.
  • Although rare, inclusion of CCH should be included in the differential diagnosis of benign solid and clear cell tumors of the vulvar skin.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Vulvar Neoplasms / pathology

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  • (PMID = 18580328.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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49. Cho KE, Son EJ, Kim JA, Youk JH, Kim EK, Kwak JY, Jeong J: Clear cell hidradenoma of the axilla: a case report with literature review. Korean J Radiol; 2010 Jul-Aug;11(4):490-2
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  • [Title] Clear cell hidradenoma of the axilla: a case report with literature review.
  • Clear cell hidradenoma is an uncommon benign skin appendageal tumor that typically involves the dermal layer of the head, face, and extremities.
  • We present a case of clear cell hidradenoma of the axillary tail with radiological findings and a literature review.
  • [MeSH-major] Adenoma, Sweat Gland / radiography. Adenoma, Sweat Gland / ultrasonography. Axilla. Sweat Gland Neoplasms / radiography. Sweat Gland Neoplasms / ultrasonography

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  • [Cites] Br J Radiol. 2007 Jan;80(949):e27-9 [17267467.001]
  • [Cites] Breast Cancer. 2007;14(3):307-11 [17690510.001]
  • [Cites] Skeletal Radiol. 2007 Dec;36(12):1185-90 [17624528.001]
  • [Cites] Clin Radiol. 2004 Dec;59(12):1142-4 [15556599.001]
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  • (PMID = 20592936.001).
  • [ISSN] 2005-8330
  • [Journal-full-title] Korean journal of radiology
  • [ISO-abbreviation] Korean J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2893323
  • [Keywords] NOTNLM ; Axilla mass / Hidradenoma / Ultrasonography
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50. Behboudi A, Winnes M, Gorunova L, van den Oord JJ, Mertens F, Enlund F, Stenman G: Clear cell hidradenoma of the skin-a third tumor type with a t(11;19)--associated TORC1-MAML2 gene fusion. Genes Chromosomes Cancer; 2005 Jun;43(2):202-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clear cell hidradenoma of the skin-a third tumor type with a t(11;19)--associated TORC1-MAML2 gene fusion.
  • Recent studies have shown that the t(11;19)(q21;p13) translocation in mucoepidermoid carcinomas and benign Warthin's tumors results in a fusion of the N-terminal CREB-binding domain of the cAMP coactivator TORC1 (a.k.a.
  • Here we show that a third tumor type, clear cell hidradenoma of the skin, also expresses this gene fusion.
  • RT-PCR analysis of a clear cell hidradenoma with a t(11;19)(q21;p13) translocation revealed expression of a TORC1-MAML2 fusion transcript consisting of exon 1 of TORC1 fused to exons 2-5 of MAML2.
  • These results demonstrate that the t(11;19) in mucoepidermoid carcinoma, Warthin's tumor, and clear cell hidradenoma targets the same genes and results in identical gene fusions, indicating that at least subgroups of these glandular tumors evolve through activation of the same molecular pathways.
  • [MeSH-major] Chromosomes, Human, Pair 11. Chromosomes, Human, Pair 19. Nuclear Proteins / genetics. Skin Neoplasms / genetics. Transcription Factors / genetics. Translocation, Genetic

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  • [Copyright] Copyright 2005 Wiley-Liss, Inc.
  • (PMID = 15729701.001).
  • [ISSN] 1045-2257
  • [Journal-full-title] Genes, chromosomes & cancer
  • [ISO-abbreviation] Genes Chromosomes Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CRTC1 protein, human; 0 / DNA Primers; 0 / DNA-Binding Proteins; 0 / MAML2 protein, human; 0 / Nuclear Proteins; 0 / Transcription Factors
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51. Monteagudo B, Iglesias B, de la Torre C, Paredes C, Vázquez-Blanco M, Ginarte M, Labandeira J: [Poroid hidradenoma]. Actas Dermosifiliogr; 2005 Jul-Aug;96(6):398-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Poroid hidradenoma].
  • Poroid hidradenoma is a recently described variant of eccrine poroma.
  • This neoplasm presents structural findings of hidradenoma (solid and cystic areas) and cytological characteristics of poromas (poroid and cuticular cells, the latter showing ductal differentiation).
  • We present a case of poroid hidradenoma in a 74-year-old woman, who consulted her physician because of a nodular lesion on the left buttock.
  • [MeSH-major] Acrospiroma / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 16476263.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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52. Dubb M, Michelow P: Cytologic features of hidradenoma in fine needle aspiration biopsies. Acta Cytol; 2009 Mar-Apr;53(2):179-82
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytologic features of hidradenoma in fine needle aspiration biopsies.
  • OBJECTIVE: To review the cytologic features of hidradenoma to describe criteria that may aid in identification of these tumors at the time of aspiration and allow for a more specific diagnosis than the umbrella term of benign skin adnexal tumor.
  • Fine needle aspiration (FNA) of these lesions showed the presence of benign skin adnexal tumors.
  • RESULTS: The following cytomorphologic findings are consistent with the diagnosis of hidradenoma: a cystic component to the aspirate as represented by amorphous background material with or without foam cells and epithelial duct-like cells and tubular structures.
  • CONCLUSION: Knowledge of the cytologic features of hidradenoma will allow for correct management of the patient and prevent misdiagnosis as a malignant tumor.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Head and Neck Neoplasms / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 19365971.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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53. Chase DM, Basu T, Saffari B, Ries S, Berman ML: Malignant eccrine spiradenoma of the vulva: a case report and review of the literature. Int J Gynecol Cancer; 2006 May-Jun;16(3):1465-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant eccrine spiradenoma of the vulva: a case report and review of the literature.
  • Malignant eccrine spiradenoma is a rare skin tumor of sweat gland origin.
  • The present case is that of a 41-year-old woman with malignant eccrine spiradenoma of the periclitoral region.
  • She had an 18-month history of a recurrent, painful mass adjacent to the clitoris.
  • As malignant eccrine spiradenoma is a rare tumor, no standard care exists for treatment and postoperative management.
  • Therefore, these patients require close postoperative follow-up for recurrent disease.
  • [MeSH-major] Acrospiroma / diagnosis. Sweat Gland Neoplasms / diagnosis. Vulvar Neoplasms / diagnosis
  • [MeSH-minor] Adenoma, Sweat Gland / diagnosis. Adult. Female. Humans. Neoplasm Recurrence, Local / prevention & control. Sentinel Lymph Node Biopsy / methods

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  • (PMID = 16803551.001).
  • [ISSN] 1048-891X
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 13
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54. Kazakov DV, Soukup R, Mukensnabl P, Boudova L, Michal M: Brooke-Spiegler syndrome: report of a case with combined lesions containing cylindromatous, spiradenomatous, trichoblastomatous, and sebaceous differentiation. Am J Dermatopathol; 2005 Feb;27(1):27-33
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Brooke-Spiegler syndrome: report of a case with combined lesions containing cylindromatous, spiradenomatous, trichoblastomatous, and sebaceous differentiation.
  • Brooke-Spiegler syndrome is an autosomal dominantly inherited disease with predisposition to cutaneous adnexal neoplasms, most commonly cylindromas and trichoepitheliomas.
  • The histopathological survey revealed a plethora of benign adnexal neoplasms showing apocrine, follicular, and sebaceous differentiation occurring independently and conjointly.
  • The occurrence of sebaceous and trichoblastic differentiation in spiradenocylindromas is a further proof that spiradenoma and cylindroma are not eccrine tumors but neoplasms of the folliculosebaceousapocrine unit.
  • [MeSH-major] Carcinoma, Skin Appendage / pathology. Neoplasms, Multiple Primary / pathology. Neoplastic Syndromes, Hereditary / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adenoma, Sweat Gland / metabolism. Adenoma, Sweat Gland / pathology. Adenoma, Sweat Gland / surgery. Aged. Biomarkers, Tumor / metabolism. Carcinoma, Adenoid Cystic / metabolism. Carcinoma, Adenoid Cystic / pathology. Carcinoma, Adenoid Cystic / surgery. Hair Diseases / metabolism. Hair Diseases / pathology. Hair Diseases / surgery. Hair Follicle / metabolism. Hair Follicle / pathology. Humans. Immunoenzyme Techniques. Male. Sebaceous Glands / metabolism. Sebaceous Glands / pathology. Syndrome

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  • (PMID = 15677973.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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55. Lee CK, Jang KT, Cho YS: Tubular apocrine adenoma with syringocystadenoma papilliferum arising from the external auditory canal. J Laryngol Otol; 2005 Dec;119(12):1004-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tubular apocrine adenoma with syringocystadenoma papilliferum arising from the external auditory canal.
  • Tubular apocrine adenoma (TAA) is a very rare sweat gland tumour.
  • [MeSH-major] Adenoma / pathology. Ear Canal / pathology. Ear Neoplasms / pathology. Neoplasms, Multiple Primary / pathology

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  • (PMID = 16354370.001).
  • [ISSN] 0022-2151
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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56. Ogawa R, Mitsuhashi K, Oki K, Hyakusoku H: A rare case of chondroid syringoma arising from the lower eyelid with ectropion. Plast Reconstr Surg; 2006 Nov;118(6):137e-140e
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Eyelids. Sweat Gland Neoplasms / diagnosis

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  • (PMID = 17051093.001).
  • [ISSN] 1529-4242
  • [Journal-full-title] Plastic and reconstructive surgery
  • [ISO-abbreviation] Plast. Reconstr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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57. Gilaberte Y, Grasa MP, Carapeto FJ: Clear cell hidradenoma. J Am Acad Dermatol; 2006 May;54(5 Suppl):248-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clear cell hidradenoma.
  • [MeSH-major] Acrospiroma / pathology. Leg. Sweat Gland Neoplasms / pathology

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  • [CommentOn] J Am Acad Dermatol. 2000 Apr;42(4):693-5 [10727324.001]
  • (PMID = 16631962.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Comment; Letter
  • [Publication-country] United States
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58. Siegel HJ, Said-Al-Naief N, Long J, Lopez-Ben RR, Klein M: Giant eccrine spiradenoma of the hand. Am J Orthop (Belle Mead NJ); 2008 Aug;37(8):E141-3
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  • [Title] Giant eccrine spiradenoma of the hand.
  • [MeSH-major] Adenoma, Sweat Gland. Hand

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  • (PMID = 18836612.001).
  • [ISSN] 1934-3418
  • [Journal-full-title] American journal of orthopedics (Belle Mead, N.J.)
  • [ISO-abbreviation] Am J. Orthop.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 15
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59. Goodden JR, Marven SS, Cohen M, de Ville McMullan PJ, Smith MF: Congenital apocrine tumour: a rare scalp tumour. Eur J Pediatr Surg; 2008 Aug;18(4):282-4
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  • We report a rare congenital scalp tumour with histological diagnosis of a congenital apocrine adenoma with features of a tubular adenoma.
  • [MeSH-major] Apocrine Glands. Head and Neck Neoplasms / congenital. Scalp. Skin Neoplasms / congenital. Sweat Gland Neoplasms / congenital

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  • (PMID = 18629773.001).
  • [ISSN] 0939-7248
  • [Journal-full-title] European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift für Kinderchirurgie
  • [ISO-abbreviation] Eur J Pediatr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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60. Ko CJ, Cochran AJ, Eng W, Binder SW: Hidradenocarcinoma: a histological and immunohistochemical study. J Cutan Pathol; 2006 Nov;33(11):726-30
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  • The diagnosis of hidradenocarcinoma is difficult due to a combination of factors including inconsistent nomenclature/ classification, rarity of the neoplasm, and variable morphology of cells composing the neoplasm.
  • We evaluated six cases of hidradenocarcinoma histologically and immunohistochemically using antibodies to gross cystic disease fluid protein-15 (GCDFP-15), carcino-embryonic antigen (CEA), epithelial membrane antigen (EMA), S-100 protein, keratin AE1/3, cytokeratin 5/6, p53, bcl-1, bcl-2, and Ki67.
  • Histology suggested concurrent eccrine and apocrine differentiation of the cases.
  • In making the diagnosis of hidradenocarcinoma, it may be unnecessary to separate hidradenocarcinoma into eccrine and apocrine categories, and although Ki67 and p53 may be helpful, histological parameters remain paramount.
  • [MeSH-major] Adenoma, Sweat Gland / metabolism. Adenoma, Sweat Gland / pathology. Ki-67 Antigen / metabolism. Sweat Gland Neoplasms / metabolism. Sweat Gland Neoplasms / pathology. Tumor Suppressor Protein p53 / metabolism

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  • (PMID = 17083691.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Carcinoembryonic Antigen; 0 / Ki-67 Antigen; 0 / Mucin-1; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / S100 Proteins; 0 / Tumor Suppressor Protein p53; 136601-57-5 / Cyclin D1; 68238-35-7 / Keratins
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61. Kazakov DV, Magro G, Kutzner H, Spagnolo DV, Yang Y, Zaspa O, Mukensnabl P, Michal M: Spiradenoma and spiradenocylindroma with an adenomatous or atypical adenomatous component: a clinicopathological study of 6 cases. Am J Dermatopathol; 2008 Oct;30(5):436-41
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  • [MeSH-major] Adenoma / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 18806484.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Keratin-14
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62. Kuwabara H, Haginomori S, Takamaki A, Ito K, Takenaka H, Kurisu Y, Tsuji M, Mori H: Lipomatous pleomorphic adenoma of the ceruminous gland. Pathol Int; 2006 Jan;56(1):51-3
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  • [Title] Lipomatous pleomorphic adenoma of the ceruminous gland.
  • A case of lipomatous pleomorphic adenoma in the ceruminous gland is reported.
  • This case demonstrates the peculiar location of a lipomatous pleomorphic adenoma in the external auditory canal.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Adenoma, Pleomorphic / pathology. Ear Canal. Ear Neoplasms / diagnosis. Sweat Gland Neoplasms / diagnosis

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  • (PMID = 16398681.001).
  • [ISSN] 1320-5463
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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63. Alkatan HM: Nodular hidradenoma of the lower eyelid. Can J Ophthalmol; 2007 Feb;42(1):149-50
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  • [Title] Nodular hidradenoma of the lower eyelid.

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  • (PMID = 17361265.001).
  • [ISSN] 0008-4182
  • [Journal-full-title] Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
  • [ISO-abbreviation] Can. J. Ophthalmol.
  • [Language] ENG
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
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64. Cashell AW: Apocrine adenoma of the breast. W V Med J; 2008 Mar-Apr;104(2):16-9
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  • [Title] Apocrine adenoma of the breast.
  • A case of apocrine adenoma, a rare benign tumor of the breast is reported.
  • Apocrine adenomas have been reported arising in a variety of sites including the breast, (1-5) perianal region, (6,7) eyelid, (8) and axilla. (9) Their appearance has similarities to the apocrine metaplasia commonly seen in fibrocystic change of the breast but they are well-circumscribed tumors with closely packed tubular and papillary structures.
  • [MeSH-major] Adenoma, Sweat Gland / diagnosis. Apocrine Glands / pathology. Breast Neoplasms / diagnosis

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  • (PMID = 18491794.001).
  • [ISSN] 0043-3284
  • [Journal-full-title] The West Virginia medical journal
  • [ISO-abbreviation] W V Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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65. Kazakov DV, Requena L, Kutzner H, Fernandez-Figueras MT, Kacerovska D, Mentzel T, Schwabbauer P, Michal M: Morphologic diversity of syringocystadenocarcinoma papilliferum based on a clinicopathologic study of 6 cases and review of the literature. Am J Dermatopathol; 2010 Jun;32(4):340-7
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  • [Title] Morphologic diversity of syringocystadenocarcinoma papilliferum based on a clinicopathologic study of 6 cases and review of the literature.
  • The purpose of our investigation was to study a series of syringocystadenocarcinoma papilliferum to document morphologic variations of the neoplasm.
  • It is concluded that morphologic diversity of syringocystadenocarcinoma papilliferum is substantial.
  • Its association with the benign counterpart and ductal changes suggests a transformation that may involve usual ductal hyperplasia-atypical ductal hyperplasia-(ductal) adenocarcinoma in situ-invasive adenocarcinoma pathway.
  • [MeSH-major] Cystadenocarcinoma, Papillary / pathology. Sweat Gland Neoplasms / pathology
  • [MeSH-minor] Adenoma, Sweat Gland / pathology. Aged. Aged, 80 and over. Carcinoma in Situ / pathology. Carcinoma, Ductal / pathology. Carcinoma, Squamous Cell / pathology. Female. Humans. Male. Middle Aged

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  • (PMID = 20216201.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 25
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66. Kamakura T, Horii A, Mishiro Y, Takashima S, Kubo T: Magnetic resonance imaging of syringocystadenoma papilliferum of the external auditory canal. Auris Nasus Larynx; 2006 Mar;33(1):53-6
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  • Signal intensities on T2-weighted images of this tumor were low compared to those of pleomorphic adenoma.
  • All ceruminous gland tumors including SCAP are thought to be potentially malignant; therefore, pre-operative biopsy should not be performed.
  • [MeSH-major] Ear Neoplasms / pathology. Ear, External / pathology. Magnetic Resonance Imaging. Sweat Gland Neoplasms / pathology. Syringoma / pathology

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  • (PMID = 16168591.001).
  • [ISSN] 0385-8146
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Contrast Media; K2I13DR72L / Gadolinium DTPA
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67. Chiu HH, Chen PH, Wu CS, Chen GS, Tsai KB, Wen CH, Lan CC: Origin of poroid hidradenoma and pigmentation mechanism of eccrine poroma: critical analysis of an unique presentation. J Eur Acad Dermatol Venereol; 2009 May;23(5):597-9
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  • [Title] Origin of poroid hidradenoma and pigmentation mechanism of eccrine poroma: critical analysis of an unique presentation.
  • [MeSH-major] Adenoma, Sweat Gland / etiology. Eccrine Glands / pathology. Skin Pigmentation

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  • (PMID = 18783473.001).
  • [ISSN] 1468-3083
  • [Journal-full-title] Journal of the European Academy of Dermatology and Venereology : JEADV
  • [ISO-abbreviation] J Eur Acad Dermatol Venereol
  • [Language] eng
  • [Publication-type] Letter
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Endothelin-1
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68. Vazmitel M, Michal M, Mukensnabl P, Kazakov DV: Syringocystadenoma papilliferum with sebaceous differentiation in an intradermal tubular apocrine component. Report of a case. Am J Dermatopathol; 2008 Feb;30(1):51-3
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  • [Title] Syringocystadenoma papilliferum with sebaceous differentiation in an intradermal tubular apocrine component. Report of a case.
  • Syringocystadenoma papilliferum is a benign tumor most commonly located on the scalp or face, and it often arises within a nevus sebaceus of Jadassohn.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Head and Neck Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Nevus, Sebaceous of Jadassohn / pathology. Skin Neoplasms / pathology. Sweat Gland Neoplasms / pathology


69. Hatanaka K, Tanimoto A, Umekita Y, Yoshioka T, Kanekura T: Unusual anogenital apocrine tumor resembling mammary-like gland adenoma in male perineum: a case report. Diagn Pathol; 2010;5:42
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  • [Title] Unusual anogenital apocrine tumor resembling mammary-like gland adenoma in male perineum: a case report.
  • A dermal cystic lesion developed in the region between the anus and scrotum of a 74-year-old Japanese male.
  • A mural nodule, measuring 1 x 1.5 cm in size, protruded into the cystic space and consisted of a solid proliferation of tubular glands with prominent apocrine secretion and basal myoepithelial cells.
  • Immunohistochemical examination showed that the luminal cells were partially positive for gross cystic disease fluid protein 15 and human milk fat globulin 1, and the basal myoepithelial cells were positive for alpha-smooth muscle actin and S-100 protein.
  • Although no mammary-like glands were present in the dermis around the tumor, this unusual apocrine tumor has been suggested to be derived from male anogenital mammary-like glands and mimic a mammary-like gland adenoma in the male perineum.
  • [MeSH-major] Adenoma / pathology. Genital Neoplasms, Male / pathology. Mammary Glands, Human / pathology. Perineum / pathology. Sweat Gland Neoplasms / pathology

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  • [Cites] Clin Exp Dermatol. 2001 Jan;26(1):88-92 [11260187.001]
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  • (PMID = 20576161.001).
  • [ISSN] 1746-1596
  • [Journal-full-title] Diagnostic pathology
  • [ISO-abbreviation] Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ PMC2907321
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70. Missall TA, Burkemper NM, Jensen SL, Hurley MY: Immunohistochemical differentiation of four benign eccrine tumors. J Cutan Pathol; 2009 Feb;36(2):190-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Immunohistochemical differentiation of four benign eccrine tumors.
  • BACKGROUND: The histogenesis and differentiation of eccrine tumors, including cylindroma, poroma, spiradenoma and syringoma, remains controversial.
  • METHODS: Ten examples each of normal eccrine structures and of four benign eccrine tumors are analyzed with antibodies to cytokeratin (CK) 7, CD34, CK6, CK10, smooth muscle actin (SMA) and CD10.
  • These markers represent two different immunohistochemical stains for each part of the eccrine structure; CK7 and CD34 stain the secretory coil, CK6 and CK10 stain the straight duct and SMA and CD10 stain the myoepithelial cells.
  • This redundancy in staining is performed on four benign eccrine tumors to better interpret the existing literature.
  • SMA appears to be a more specific marker for myoepithelial cells surrounding normal eccrine coils, and none of the studied tumors express SMA or CD10.
  • CONCLUSIONS: Our studies suggest that syringomas are tumors of the eccrine duct, while cylindromas and spiradenomas are tumors of the secretory coil.
  • [MeSH-major] Adenoma, Sweat Gland. Antigens, CD34 / biosynthesis. Biomarkers, Tumor / biosynthesis. Keratins / biosynthesis. Neprilysin / biosynthesis. Sweat Gland Neoplasms / metabolism
  • [MeSH-minor] Humans. Sweat Glands / metabolism. Sweat Glands / pathology

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  • (PMID = 18564284.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Biomarkers, Tumor; 68238-35-7 / Keratins; EC 3.4.24.11 / Neprilysin
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71. Villalón G, Monteagudo C, Martín JM, Ramón D, Alonso V, Jordá E: [Chondroid syringoma: a clinical and histological review of eight cases]. Actas Dermosifiliogr; 2006 Nov;97(9):573-7
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  • [Transliterated title] Siringoma condroide: revisión clínica e histológica de ocho casos.
  • INTRODUCTION: Chondroid syringoma is a rare skin tumor that presents as a slow growing, indolent lesion, that is more frequent in male adults and is usually benign.
  • It can be classified as eccrine and apocrine according to its pathological characteristics.
  • DISCUSSION: The chondroid syringoma is usually a small-sized skin tumor, frequently on the head and neck.
  • As a general rule, it is a benign tumor.
  • Some authors have proposed the term of atypical mixed tumor of the skin for those chondroid syringomas with histological traits of malignancy but without evidence of metastasis.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 17173760.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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72. Gonzalez Guemes M, Gonzalez Hermosa R, Calderon Gutierrez MJ, Gonzalez-Perez R, Saracibar Oyon N, Soloeta Arechavala R: Development of multiple tumours arising in a nevus sebaceus of Jadassohn. J Eur Acad Dermatol Venereol; 2005 Sep;19(5):658-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenoma, Sweat Gland / diagnosis. Neoplasms, Multiple Primary / pathology. Nevus, Pigmented / pathology. Skin Neoplasms / pathology

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  • (PMID = 16164741.001).
  • [ISSN] 0926-9959
  • [Journal-full-title] Journal of the European Academy of Dermatology and Venereology : JEADV
  • [ISO-abbreviation] J Eur Acad Dermatol Venereol
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Netherlands
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73. Yu G, Goodloe S Jr, D'Angelis CA, McGrath BE, Chen F: Giant clear cell hidradenoma of the knee. J Cutan Pathol; 2010 Sep;37(9):e37-41
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant clear cell hidradenoma of the knee.
  • Hidradenomas, also referred to as nodular hidradenomas or clear cell hidradenomas (CCH), are benign cutaneous eccrine tumors usually 2-3 cm in dimension.
  • We report a case of an 8.0 x 6.0 x 3.0 cm clear cell hidradenoma of the left knee in a 43-year-old man.
  • Grossly, the resected tumor was unencapsulated and tan, with a solid and cystic cut surface showing papillary excrescences on the cyst wall.
  • [MeSH-major] Acrospiroma / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 19615032.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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74. Yosepovich A, Perelman M, Ayalon S, Papa M, Kopolovic J: Syringomatous adenoma of the nipple: a case report. Pathol Res Pract; 2005;201(5):405-7
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  • [Title] Syringomatous adenoma of the nipple: a case report.
  • We present a case of a 33-year-old woman who underwent excisional breast biopsy due to a left nipple mass.
  • Histological examination revealed the morphologic and immunohistochemical pattern of syringomatous adenoma of the nipple.
  • This is a rare lesion of the breast that can clinically mimic breast carcinoma, but harbors a benign and only locally aggressive course.
  • [MeSH-major] Breast Neoplasms / pathology. Nipples. Sweat Gland Neoplasms / pathology. Syringoma / pathology

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  • (PMID = 16047951.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Actins
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75. Winnes M, Mölne L, Suurküla M, Andrén Y, Persson F, Enlund F, Stenman G: Frequent fusion of the CRTC1 and MAML2 genes in clear cell variants of cutaneous hidradenomas. Genes Chromosomes Cancer; 2007 Jun;46(6):559-63
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  • Here we show that the CRTC1-MAML2 gene fusion is also frequent in benign hidradenomas of the skin.
  • Taken together, the present and previous observations indicate that the CRTC1-MAML2 fusion is etiologically linked to benign and low-grade malignant tumors originating from diverse exocrine glands rather than being linked to a separate tumor entity.
  • [MeSH-major] Adenoma, Sweat Gland / genetics. Adenoma, Sweat Gland / metabolism. Oncogene Proteins, Fusion / metabolism. Sweat Gland Neoplasms / genetics. Sweat Gland Neoplasms / metabolism

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  • [Copyright] (c) 2007 Wiley-Liss, Inc.
  • (PMID = 17334997.001).
  • [ISSN] 1045-2257
  • [Journal-full-title] Genes, chromosomes & cancer
  • [ISO-abbreviation] Genes Chromosomes Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / MECT1-MAML2 fusion protein, human; 0 / Oncogene Proteins, Fusion
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76. Abdulla AN, Covert AA, Grantmyre JE: Scrotal syringocystadenoma papilliferum: case report. Can J Urol; 2009 Jun;16(3):4684-6
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  • Syringocystadenoma papilliferum (SCAP) is a benign rare adnexal skin neoplasm, which in a third of cases arises from a nevus sebaceous and is most commonly found on the head and neck and in very rare instances found on the genitalia.
  • Following excision and histological confirmation of a noninfiltrative process, the patient remains asymptomatic.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Scrotum / pathology. Skin Neoplasms / pathology. Syringoma / pathology

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  • (PMID = 19497181.001).
  • [ISSN] 1195-9479
  • [Journal-full-title] The Canadian journal of urology
  • [ISO-abbreviation] Can J Urol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Canada
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77. Canedo T, de Almeida MP, Cuzzi T, Ramos-e-Silva M: Immunophenotypic aspects of cylindroma and nodular hidradenoma. J Eur Acad Dermatol Venereol; 2010 Feb;24(2):178-85
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  • [Title] Immunophenotypic aspects of cylindroma and nodular hidradenoma.
  • OBJECTIVES: To evaluate the eccrine and/or apocrine differentiation phenotype in cases of cylindroma and clear cell hidradenoma with CD15 and p63 antibodies.
  • METHODOLOGY: Slides and blocks of six cases of cylindroma and seven cases of nodular hidradenoma (clear cells) were analyzed by the technique of immunohistochemistry with CD15 and p63 antibodies.
  • In five of seven cases of nodular hidradenoma (clear cell), we could easily observe clear cells between 20% and 50% of tumour cells.
  • CONCLUSIONS: The present study suggests eccrine origin for both tumours: cylindroma and clear cell hidradenoma.
  • [MeSH-major] Acrospiroma / immunology. Carcinoma, Adenoid Cystic / immunology. Immunophenotyping

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  • (PMID = 19796089.001).
  • [ISSN] 1468-3083
  • [Journal-full-title] Journal of the European Academy of Dermatology and Venereology : JEADV
  • [ISO-abbreviation] J Eur Acad Dermatol Venereol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antigens, CD15; 0 / CKAP4 protein, human; 0 / Membrane Proteins
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78. Volmar KE, Cummings TJ, Wang WH, Creager AJ, Tyler DS, Xie HB: Clear cell hidradenoma: a mimic of metastatic clear cell tumors. Arch Pathol Lab Med; 2005 May;129(5):e113-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clear cell hidradenoma: a mimic of metastatic clear cell tumors.
  • Clear cell hidradenoma is a benign skin appendage tumor that may mimic conventional-type renal cell carcinoma.
  • Histologically, clear cell hidradenoma contains small ductular lumens, focal apocrine and squamoid change, and a less prominent vascular pattern than renal cell carcinoma.
  • Knowing the cytologic features of primary skin adnexal neoplasms helps distinguish them from cutaneous metastases, which are more commonly referred for fine-needle aspiration biopsy evaluation.
  • We report the rare case of a patient with renal cell carcinoma who underwent excision of an axillary clear cell hidradenoma, which was clinically suggestive of cutaneous metastatic disease.
  • [MeSH-major] Adenoma, Sweat Gland / diagnosis. Carcinoma, Renal Cell / diagnosis. Kidney Neoplasms / diagnosis. Neoplasms, Multiple Primary / diagnosis. Sweat Gland Neoplasms / diagnosis

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  • (PMID = 15859654.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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79. Tey HL: Characterizing the nature of eccrine syringofibroadenoma: illustration with a case showing spontaneous involution. Clin Exp Dermatol; 2009 Jul;34(5):e66-8
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  • [Title] Characterizing the nature of eccrine syringofibroadenoma: illustration with a case showing spontaneous involution.
  • Eccrine syringofibroadenoma (ESFA) is a histological entity.
  • Reactive ESFA represents a hyperplastic and hamartomatous process, and may be more appropriately known as reactive eccrine syringofibroadenomatosis.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Fibroadenoma / pathology. Sweat Gland Neoplasms / pathology
  • [MeSH-minor] Aged. Eccrine Glands. Female. Humans. Leprosy, Lepromatous / complications. Neoplasm Regression, Spontaneous

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  • (PMID = 19438523.001).
  • [ISSN] 1365-2230
  • [Journal-full-title] Clinical and experimental dermatology
  • [ISO-abbreviation] Clin. Exp. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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80. Puri PK, Galan A, Glusac EJ, Cowper SE: Metastatic cutaneous carcinoid tumor mimicking an adnexal poroid neoplasm. J Cutan Pathol; 2008 Jan;35(1):54-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenoma, Sweat Gland / diagnosis. Apocrine Glands / pathology. Carcinoid Tumor / diagnosis. Skin Neoplasms / diagnosis. Sweat Gland Neoplasms / diagnosis

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  • (PMID = 18095995.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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81. Tolland JP, Brenn T, Guldbakke KK, Schanbacher CF: Mohs micrographic surgery, sentinel lymph node mapping, and estrogen receptor analysis for the treatment of malignant nodular hidradenoma. Dermatol Surg; 2006 Oct;32(10):1294-301
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mohs micrographic surgery, sentinel lymph node mapping, and estrogen receptor analysis for the treatment of malignant nodular hidradenoma.
  • [MeSH-major] Adenoma, Sweat Gland. Mohs Surgery / methods. Receptors, Estrogen / metabolism. Sweat Gland Neoplasms

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  • (PMID = 17034384.001).
  • [ISSN] 1076-0512
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Receptors, Estrogen
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82. Scurry J, van der Putte SC, Pyman J, Chetty N, Szabo R: Mammary-like gland adenoma of the vulva: review of 46 cases. Pathology; 2009;41(4):372-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mammary-like gland adenoma of the vulva: review of 46 cases.
  • AIMS: Hidradenoma papilliferum (HP) of the anogenital region, which was previously thought to be an apocrine tumour, is now believed to be derived from anogenital mammary-like glands (MLG) and is more accurately termed MLG adenoma.
  • Unusual architectural patterns resembled breast lesions such as erosive adenomatosis, sclerosing adenosis and ductal adenoma.
  • CONCLUSIONS: MLG adenomas demonstrate a marked diversity in histological pattern and cell morphology.
  • Unusual vulvar tumours, which have been previously reported as erosive adenomatosis, sclerosing adenosis, papillary adenofibroma, syringocystadenoma papilliferans, etc., are variants of MLG adenomas.
  • [MeSH-major] Adenoma / pathology. Mammary Glands, Human / pathology. Vulvar Neoplasms / pathology

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  • (PMID = 19404851.001).
  • [ISSN] 1465-3931
  • [Journal-full-title] Pathology
  • [ISO-abbreviation] Pathology
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 46
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83. Retamar RA, Stengel F, Saadi ME, Kien MC, Della Giovana P, Cabrera H, Chouela EN: Brooke-Spiegler syndrome - report of four families: treatment with CO2 laser. Int J Dermatol; 2007 Jun;46(6):583-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Brooke-Spiegler syndrome is a well known but rare cutaneous disorder characterized by the presence of multiple trichoepitheliomas and cylindromas.
  • [MeSH-major] Adenoma, Sweat Gland / surgery. Carcinoma, Adenoid Cystic / surgery. Laser Therapy. Neoplasms, Adnexal and Skin Appendage / surgery. Neoplasms, Multiple Primary / surgery. Neoplastic Syndromes, Hereditary / surgery. Skin Neoplasms / surgery

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  • (PMID = 17550556.001).
  • [ISSN] 0011-9059
  • [Journal-full-title] International journal of dermatology
  • [ISO-abbreviation] Int. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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84. Guan Y, Xiao Y, Ji HA, Xue CW, Li P: [Poroid hidradenoma: a case report]. Zhonghua Bing Li Xue Za Zhi; 2006 Jun;35(6):378-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Poroid hidradenoma: a case report].
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Skin Neoplasms / pathology

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  • (PMID = 16834920.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
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85. Shah SS, Adelson M, Mazur MT: Adenocarcinoma in situ arising in vulvar papillary hidradenoma: report of 2 cases. Int J Gynecol Pathol; 2008 Jul;27(3):453-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenocarcinoma in situ arising in vulvar papillary hidradenoma: report of 2 cases.
  • Adenocarcinoma in situ rarely occurs in vulvar papillary hidradenoma.
  • We encountered 2 cases of adenocarcinoma in situ arising in a papillary hidradenoma of the vulva.
  • On microscopic examination, the tumors showed focal features of benign hidradenoma at the periphery with transitions into areas of increasing cytologic atypia that fulfilled criteria for adenocarcinoma in situ similar to that seen in the breast.
  • Both lesions show areas strongly immunoreactive for mammaglobin and gross cystic disease fluid protein 15 as well as estrogen and progesterone receptor protein in 1 case.
  • There was no evidence of benign ectopic breast tissue within or adjacent to the neoplasms.
  • The fact that these tumors displayed morphologic and immunohistochemical features that resembled ductal carcinoma in situ of the breast demonstrates the close homology between papillary hidradenoma and breast epithelium.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma, Sweat Gland / pathology. Carcinoma in Situ / pathology. Vulvar Neoplasms / pathology
  • [MeSH-minor] Aged, 80 and over. Disease Progression. Female. Humans

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  • (PMID = 18580327.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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86. Shah BK, Qamruzzaman Y, Serban K, Hire E, Ying SC: First case report of locally advanced malignant nodular hidradenoma of the scrotum. Onkologie; 2010;33(12):701-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] First case report of locally advanced malignant nodular hidradenoma of the scrotum.
  • BACKGROUND: Malignant nodular hidradenoma (MNH) is a malignant tumor of the eccrine glands, and most commonly involves the head, trunk, and extremities.
  • CASE REPORT: We describe the case of a 30-year-old African American man who was diagnosed with locally advanced MNH of the scrotum and treated with surgery.
  • More than 2 years after surgery, the patient is without evidence of disease.
  • [MeSH-major] Acrospiroma / pathology. Genital Neoplasms, Male / pathology. Scrotum / pathology. Sweat Gland Neoplasms / pathology

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  • [Copyright] Copyright © 2010 S. Karger AG, Basel.
  • (PMID = 21124043.001).
  • [ISSN] 1423-0240
  • [Journal-full-title] Onkologie
  • [ISO-abbreviation] Onkologie
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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87. Nibe K, Uchida K, Itoh T, Tateyama S: A case of canine apocrine sweat gland adenoma, clear cell variant. Vet Pathol; 2005 Mar;42(2):215-8
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  • [Title] A case of canine apocrine sweat gland adenoma, clear cell variant.
  • A cutaneous mass at the base of the retroauricular region of a 4-year-old, female Golden Retriever was examined pathologically.
  • Histologically, the mass formed multiple nodules consisting of a proliferation of large clear cells with abundant cytoplasm.
  • On the basis of these findings, the present tumor was diagnosed as apocrine sweat gland adenoma, clear cell variant.
  • There have been few previous reports of canine apocrine adenomas showing a clear cell morphology.
  • [MeSH-major] Adenoma, Sweat Gland / veterinary. Dog Diseases / pathology. Sweat Gland Neoplasms / veterinary

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  • (PMID = 15753476.001).
  • [ISSN] 0300-9858
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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88. Rammeh-Rommani S, Ben Ghanem A, Laatiri N, Jenhani F, Fezaa B, Kammoun MR, Baltagi Ben Jilani S, Zermani R: [Study of the ploidy and cellular cycle of hidradenomas and hidradenocarcinomas: a series of 13 cases]. Tunis Med; 2007 May;85(5):409-12
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  • [Transliterated title] Etude de la ploïdie et du cycle cellulaire des hidradenomes et des hidradenocarcinomes: a propos d'une série de 13 cas.
  • AIMS: To study by flow cytometry (FCM) the ploidy and the cellular cycle of nodular hidradenoma (NH) and hidradenocarcinoma (HC) and to assess the prognostic utility of this technique in such tumors.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Cell Cycle. Ploidies. Sweat Gland Neoplasms / pathology

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  • (PMID = 17657929.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Tunisia
  • [Chemical-registry-number] 0 / DNA, Neoplasm
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89. Biedrzycki OJ, Rufford B, Wilcox M, Barton DP, Jameson C: Malignant clear cell hidradenoma of the vulva: report of a unique case and review of the literature. Int J Gynecol Pathol; 2008 Jan;27(1):142-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant clear cell hidradenoma of the vulva: report of a unique case and review of the literature.
  • Clear cell hidradenoma (CCH) is a rare tumor derived from eccrine sweat glands with a predilection for the head, face, and upper extremities.
  • A previously healthy 39-year-old woman underwent marsupialization of a presumed left-side vulval Bartholin gland cyst.
  • It also highlights the importance of considering MCCH in the differential diagnosis of a lymph node containing a metastatic clear cell tumor or an apparent metastatic clear cell lesion in the skin.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Sweat Gland Neoplasms / pathology. Vulvar Neoplasms / pathology

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  • (PMID = 18156989.001).
  • [ISSN] 0277-1691
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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90. Vazmitel M, Pavlovsky M, Kacerovska D, Michal M, Kazakov DV: Pseudoangiomatous stromal hyperplasia in a complex neoplastic lesion involving anogenital mammary-like glands. J Cutan Pathol; 2009 Oct;36(10):1117-20
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  • Pseudoangiomatous stromal hyperplasia (PASH), a relatively frequent hormonal change associated with different benign and malignant processes in the breast, was only once mentioned in the literature concerning the pathology of AMLG.
  • The present case of PASH is remarkable because of its occurrence within a complex lesion evidencing the changes identical to or reminiscent of blunt duct adenosis, fibroadenoma and hidradenoma papilliferum.

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  • [Copyright] 2009 John Wiley & Sons A/S.
  • (PMID = 19508499.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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91. Nishizawa A, Nakanishi Y, Sasajima Y, Yamazaki N, Yamamoto A: Syringoid eccrine carcinoma with apparently aggressive transformation: case report and review of the literature. Int J Dermatol; 2006 Oct;45(10):1218-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Syringoid eccrine carcinoma with apparently aggressive transformation: case report and review of the literature.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 17040446.001).
  • [ISSN] 0011-9059
  • [Journal-full-title] International journal of dermatology
  • [ISO-abbreviation] Int. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 27
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92. Lin D, Perri AJ 3rd, Weaver JM, Colome MI, Raimer SS: What is your diagnosis? Benign acrospiroma. Cutis; 2009 Jan;83(1):12, 21-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] What is your diagnosis? Benign acrospiroma.
  • [MeSH-major] Acrospiroma / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 19271564.001).
  • [ISSN] 0011-4162
  • [Journal-full-title] Cutis
  • [ISO-abbreviation] Cutis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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93. Ohtsuki Y, Ohtsuka H, Kurabayashi A, Iguchi M, Matsumoto M, Takeuchi T, Lee GH, Furihata M: Immunohistochemical and electron microscopic studies of Langerhans cells in a case of multiple eccrine spiradenomas. Med Mol Morphol; 2007 Dec;40(4):221-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Immunohistochemical and electron microscopic studies of Langerhans cells in a case of multiple eccrine spiradenomas.
  • Multiple eccrine spiradenomas are rare.
  • In the present study, a detailed investigation of eccrine spiradenoma was performed, focusing in particular on the presence of Langerhans cells (LCs) in the tumor, and their immunohistochemical and ultrastructural characterization.
  • They were diagnosed as eccrine spiradenoma and were composed of small and large tumor cells with a dense fibrous capsule in the dermis.
  • In these examinations of eccrine spiradenoma, LCs, approximately 15/HPF in the tumor, were distinctly detected even at light microscopic level as negative for various types of cytokeratin stains, although they were positive for S-100 protein and CD1a, whereas on ultrastructural examination Birbeck granules were demonstrated in their cytoplasm.
  • Determination of the significance of these LCs in eccrine spiradenoma requires further investigation of a larger number of cases.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Adenoma, Sweat Gland / ultrastructure. Eccrine Glands / pathology. Eccrine Glands / ultrastructure. Langerhans Cells / pathology. Langerhans Cells / ultrastructure. Sweat Gland Neoplasms / pathology

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  • [Cites] Pathol Int. 2004 May;54(5):302-10 [15086834.001]
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  • (PMID = 18085383.001).
  • [ISSN] 1860-1480
  • [Journal-full-title] Medical molecular morphology
  • [ISO-abbreviation] Med Mol Morphol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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94. Angulo J, Jaqueti G, Kutzner H, Requena L: Squamous cell apocrine hidradenoma. J Cutan Pathol; 2007 Oct;34(10):801-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Squamous cell apocrine hidradenoma.
  • Apocrine hidradenoma is a benign adnexal neoplasm with apocrine differentiation.
  • We report two cases of apocrine hidradenoma mostly composed of squamous cells.
  • The solid aggregations of neoplastic cells were composed of a peripheral layer of basaloid polygonal cells, whereas squamous cells forming the bulk of the aggregations.
  • The rare cases described in this report are exceptional because most of the neoplastic cells showed squamous appearance and for that reason we think that squamous cell apocrine hidradenoma is the most appropriate name for these neoplasms.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Neoplasms, Squamous Cell / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 17880588.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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95. Gonul M, Cakmak SK, Gul U, Han O, Karagece U: A skin tumor in a young girl. Diagnosis: Clear cell hidradenoma. Indian J Dermatol Venereol Leprol; 2010 Jul-Aug;76(4):445-6
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  • [Title] A skin tumor in a young girl. Diagnosis: Clear cell hidradenoma.
  • [MeSH-major] Acrospiroma / pathology. Skin / pathology. Skin Neoplasms / pathology

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  • (PMID = 20657141.001).
  • [ISSN] 0973-3922
  • [Journal-full-title] Indian journal of dermatology, venereology and leprology
  • [ISO-abbreviation] Indian J Dermatol Venereol Leprol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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96. Kazakov DV, Belousova IE, Bisceglia M, Calonje E, Emberger M, Grayson W, Hantschke M, Kempf W, Kutzner H, Michal M, Spagnolo DV, Virolainen S, Zelger B: Apocrine mixed tumor of the skin ("mixed tumor of the folliculosebaceous-apocrine complex"). Spectrum of differentiations and metaplastic changes in the epithelial, myoepithelial, and stromal components based on a histopathologic study of 244 cases. J Am Acad Dermatol; 2007 Sep;57(3):467-83
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  • [Title] Apocrine mixed tumor of the skin ("mixed tumor of the folliculosebaceous-apocrine complex"). Spectrum of differentiations and metaplastic changes in the epithelial, myoepithelial, and stromal components based on a histopathologic study of 244 cases.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Apocrine Glands. Skin Neoplasms / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 17707152.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 104
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97. Plaza JA, Ortega PF, Stockman DL, Suster S: Value of p63 and podoplanin (D2-40) immunoreactivity in the distinction between primary cutaneous tumors and adenocarcinomas metastatic to the skin: a clinicopathologic and immunohistochemical study of 79 cases. J Cutan Pathol; 2010 Apr;37(4):403-10
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  • [Title] Value of p63 and podoplanin (D2-40) immunoreactivity in the distinction between primary cutaneous tumors and adenocarcinomas metastatic to the skin: a clinicopathologic and immunohistochemical study of 79 cases.
  • The distinction of metastatic carcinomas to the skin from poorly differentiated primary cutaneous carcinomas and sometimes primary benign adnexal tumors can pose a significant diagnostic challenge.
  • The purpose of this study was to evaluate the role of p63 and podoplanin (D2-40) immunoreactivity for separating primary skin tumors vs. cutaneous metastases of carcinomas from internal organs.
  • The 37 primary cutaneous tumors included 14 cases of benign adnexal tumors, 9 malignant skin adnexal neoplasms, and 14 primary squamous and basal cell carcinomas.
  • The 42 metastatic adenocarcinomas all corresponded to metastases from patients with a well-documented history of a primary tumor at another location.
  • We found variable positivity with podoplanin in all primary cutaneous neoplasms including spiradenoma (6/6), hidradenoma (2/4), cylindroma (3/3), desmoplastic trichilemmoma (1/1), poorly differentiated squamous cell carcinoma (4/4), sebaceous carcinoma (1/1), basal cell carcinoma (4/10), trichilemmal carcinoma (2/2), eccrine carcinoma (3/3), microcystic adnexal carcinoma (1/1), adnexal carcinoma NOS (1/1), and porocarcinoma (1/1).
  • Sensitivity, specificity, and positive and negative predictive values of podoplanin and p63 immunoreactivity to separate primary skin neoplasms from metastatic carcinomas were 78.4, 100.0, 100.0 and 84.0% for podoplanin, respectively, and 100.0, 100.0, 100.0 and 100.0% for p63, respectively.
  • The differences in p63 and podoplanin immunohistochemical expression between primary skin tumors and metastatic carcinomas to the skin were statistically significant (p < 0, 0001).
  • The results of our study suggest that the combined expression of p63 and podoplanin are a useful adjunct for the diagnosis of skin tumors in the clinical setting of a questionable metastasis and may be relatively specific for distinguishing primary skin tumors from metastatic carcinomas to the skin.
  • [MeSH-major] Adenocarcinoma / metabolism. Membrane Glycoproteins / metabolism. Membrane Proteins / metabolism. Skin / metabolism. Skin Neoplasms / metabolism

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  • (PMID = 20377670.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / CKAP4 protein, human; 0 / Membrane Glycoproteins; 0 / Membrane Proteins; 0 / PDPN protein, human
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98. Minami S, Sadanobu N, Ito T, Natsuaki M, Yamanishi K: Non-anogenital (ectopic) hidradenoma papilliferum with sebaceous differentiation: a case report and review of reported cases. J Dermatol; 2006 Apr;33(4):256-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Non-anogenital (ectopic) hidradenoma papilliferum with sebaceous differentiation: a case report and review of reported cases.
  • Hidradenoma papilliferum is a benign tumor that usually occurs in the female anogenital region.
  • We present a 52-year-old male with a non-anogenital (ectopic) hidradenoma papilliferum on his face.
  • The lesion contained sebaceous differentiation, which has not been previously documented in the histopathology of hidradenoma papilliferum.
  • We review the published work of non-anogenital (ectopic) hidradenoma papilliferum tumors on the head and neck.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Facial Neoplasms / pathology. Sebaceous Gland Neoplasms / pathology

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  • (PMID = 16674789.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 12
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99. Docimo S Jr, Shon W, Elkowitz DE: Bartholin's abscess arising within hidradenoma papilliferum of the vulva: a case report. Cases J; 2008;1(1):282
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bartholin's abscess arising within hidradenoma papilliferum of the vulva: a case report.
  • BACKGROUND: Hidradenoma papilliferum is an uncommon, benign, cystic, papillary tumor that occurs almost exclusively in the female anogenital region.
  • Concomitant presentation of Bartholin's abscess and Hidradenoma papilliferum is unique.
  • During excision and draining, an additional tan-brown dermal nodule was removed which demonstrated histological features of Hidradenoma papilliferum.
  • CONCLUSION: We present what we believe to be the first case of Bartholin's abscess arising in hidradenoma papilliferum and its clinical significance.

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  • (PMID = 18959791.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2584079
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100. Woestenborghs H, Van Eyken P, Dans A: Syringocystadenocarcinoma papilliferum in situ with pagetoid spread: a case report. Histopathology; 2006 Jun;48(7):869-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Carcinoma in Situ / pathology. Paget Disease, Extramammary / pathology. Sweat Gland Neoplasms / pathology. Syringoma / pathology

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  • (PMID = 16722938.001).
  • [ISSN] 0309-0167
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
  • [Chemical-registry-number] 0 / KRT7 protein, human; 0 / Keratin-7; 68238-35-7 / Keratins
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