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1. Agrawal A, Kumar A, Sinha AK, Kumar B, Sabira KC: Chondroid syringoma. Singapore Med J; 2008 Feb;49(2):e33-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chondroid syringoma.
  • Pleomorphic adenoma, or chondroid syringoma (CS), is a rare, benign, skin appendageal tumour.
  • Because of the unremarkable clinical presentation of this rare tumour, the diagnosis is made on microscopic examination.
  • We present a case of a CS located over the forehead of a 32-year-old man.
  • In the evaluation of a middle-aged male patient with a small cutaneous nodule in the head and neck region, chondroid syringoma should also be considered in the differential diagnosis.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Forehead / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 18301822.001).
  • [ISSN] 0037-5675
  • [Journal-full-title] Singapore medical journal
  • [ISO-abbreviation] Singapore Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
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2. Nagata S, Jin YF, Yoshizato K, Kitamura M, Iizuka N, Song M, Tomoeda M, Yuki M, Kubo C, Yoshizawa H, Outani H, Hamada K, Araki N, Funauchi M, Tomita Y: Early uptake and continuous accumulation of thallium-201 chloride in a benign mixed tumor of soft tissue: case report. Diagn Pathol; 2010;5:34
Hazardous Substances Data Bank. THALLOUS CHLORIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Early uptake and continuous accumulation of thallium-201 chloride in a benign mixed tumor of soft tissue: case report.
  • A case of benign mixed tumor of the soft tissue in a 64-year-old Japanese male is presented.
  • The patient underwent a resection of tumor, and the pathological diagnosis was a benign mixed tumor of soft tissue without high vascularity, characterized by histological features similar to pleomorphic adenomas in the salivary glands.
  • Immunohistochemical study proved expression of Na+/K+-ATPase of tumor cells.
  • Overexpression of Na+/K+-ATPase of the tumor might be responsible for the early uptake of Tl-201, and poor vascular structure in this tumor might lead to continuous accumulation.
  • The Tl-201 scintigraphic features of mixed tumor of soft tissue are assessed to resemble those of malignant soft tissue tumors.
  • [MeSH-major] Neoplasms, Complex and Mixed / radionuclide imaging. Radiopharmaceuticals. Soft Tissue Neoplasms / radionuclide imaging. Thallium. Tomography, Emission-Computed

  • Hazardous Substances Data Bank. THALLIUM, ELEMENTAL .
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  • [Cites] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001 Aug;92(2):228-35 [11505272.001]
  • [Cites] J Orthop Sci. 2002;7(3):304-12 [12077654.001]
  • [Cites] Am J Surg Pathol. 2003 Sep;27(9):1183-96 [12960802.001]
  • [Cites] Brain Res. 1989 Feb 20;480(1-2):259-67 [2469513.001]
  • [Cites] Biochem Pharmacol. 1992 Feb 18;43(4):803-7 [1311590.001]
  • [Cites] Am J Physiol. 1994 Feb;266(2 Pt 1):C515-23 [8141265.001]
  • [Cites] Ann Diagn Pathol. 2007 Jun;11(3):190-8 [17498593.001]
  • [Cites] J Nucl Med. 1996 Jun;37(6):955-8 [8683319.001]
  • [Cites] Am J Surg Pathol. 1997 Jan;21(1):13-22 [8990137.001]
  • [Cites] J Orthop Sci. 1998;3(6):297-303 [9811980.001]
  • [Cites] Virchows Arch. 1999 May;434(5):393-400 [10389622.001]
  • [Cites] Dentomaxillofac Radiol. 2005 Jul;34(4):212-7 [15961594.001]
  • [Cites] Ann Nucl Med. 2005 Sep;19(6):461-8 [16248382.001]
  • [Cites] J Cell Physiol. 1994 Jul;160(1):113-20 [8021291.001]
  • (PMID = 20509963.001).
  • [ISSN] 1746-1596
  • [Journal-full-title] Diagnostic pathology
  • [ISO-abbreviation] Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 7791-12-0 / thallium chloride; AD84R52XLF / Thallium; EC 3.6.3.9 / Sodium-Potassium-Exchanging ATPase
  • [Other-IDs] NLM/ PMC2887811
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3. Shimosawa H, Susa M, Honma T, Hiraishi E, Sakihara H: Soft tissue mixed tumor of the hand. Rare Tumors; 2009;1(2):e30

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Soft tissue mixed tumor of the hand.
  • Mixed tumors are relatively common in the skin and salivary glands, but extremely rare in soft tissues, often resulting in diagnostic problems.
  • The occurrence of these tumors in the hand is especially limited.
  • In this article we report the clinical, radiological, and histological features of a mixed tumor of the hypothenar region of the right hand.

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  • (PMID = 21139909.001).
  • [ISSN] 2036-3613
  • [Journal-full-title] Rare tumors
  • [ISO-abbreviation] Rare Tumors
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2994479
  • [Keywords] NOTNLM ; hand / immunohistochemistry. / mixed tumor / soft tissue
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4. Varsori M, Dettwiler S, Chaloupka K: [Eyelid chondroid syringoma: a case report]. J Fr Ophtalmol; 2007 Jan;30(1):e3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Eyelid chondroid syringoma: a case report].
  • [Transliterated title] Syringome chondroïde de la paupière: à propos d'un cas.
  • Chondroid syringoma is a rare benign skin tumor of the head and neck.
  • The lesion was surgically removed, and the histopathological examination showed a chondroid syringoma.
  • Knowledge of this disease is important because malignant transformations do occur.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Eyelid Neoplasms / diagnosis

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  • (PMID = 17287665.001).
  • [ISSN] 1773-0597
  • [Journal-full-title] Journal français d'ophtalmologie
  • [ISO-abbreviation] J Fr Ophtalmol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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5. Smiri KH, Fenniche S, Marrak H, Daoud L, Debbiche A, Ben Ayed M, Mokhtar I: [Chondroid syringoma]. Tunis Med; 2005 Jun;83(6):372-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Chondroid syringoma].
  • [Transliterated title] Le syringome chondroïde.
  • Chondroid syringoma is a benign sweat gland tumor.
  • This lesion is electively located in the craniofacial area, made of a subcutaneous painless tumor measuring from 0.5 to 3 cm.
  • Diagnosis can always be confirmed by histology which shows tubuloalveolar and gland like structures with two or more cuboidal cell lines in a fibroadipoid or chondroid stroma that is positively stained for Alcian blue.
  • Mixed tumors have a slow course; their progress to malignancy is rare but possible.
  • [MeSH-major] Adenoma, Pleomorphic / surgery. Salivary Gland Neoplasms / surgery
  • [MeSH-minor] Adult. Disease Progression. Humans. Male. Middle Aged. Patient Satisfaction. Prognosis. Retrospective Studies. Treatment Outcome

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  • (PMID = 16156416.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Tunisia
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6. Kim H, Nakaichi M, Itamoto K, Taura Y: Malignant mixed tumor in the salivary gland of a cat. J Vet Sci; 2008 Sep;9(3):331-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant mixed tumor in the salivary gland of a cat.
  • The presence of a malignant mixed tumor, also known as a carcinosarcoma, in the salivary gland is very rare.
  • Such tumors, which are typically aggressive, are characterized by the presence of carcinomatous and sarcomatous components.
  • Histopathological analysis of the mass revealed that it was a malignant mixed tumor.
  • [MeSH-major] Adenocarcinoma / veterinary. Cat Diseases / pathology. Cat Diseases / radiography. Chondrosarcoma / veterinary. Salivary Gland Neoplasms / veterinary

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  • [Cites] AJNR Am J Neuroradiol. 1995 Sep;16(8):1733-5 [7502984.001]
  • [Cites] AJNR Am J Neuroradiol. 1997 Nov-Dec;18(10):1944-8 [9403459.001]
  • [Cites] J Otolaryngol. 2005 Feb;34(1):66-9 [15966481.001]
  • [Cites] Otolaryngol Head Neck Surg. 1999 Nov;121(5):627-32 [10547484.001]
  • [Cites] Australas Radiol. 1999 Nov;43(4):520-2 [10901971.001]
  • [Cites] Pathol Annu. 1993;28 Pt 1:279-328 [8380049.001]
  • [Cites] J Am Anim Hosp Assoc. 2001 Sep-Oct;37(5):478-82 [11563448.001]
  • [Cites] Auris Nasus Larynx. 2003 Dec;30(4):439-42 [14656574.001]
  • [Cites] J Comp Pathol. 1975 Jan;85(1):77-85 [165225.001]
  • [Cites] Arch Otolaryngol. 1984 Mar;110(3):172-6 [6322732.001]
  • [Cites] Oral Surg Oral Med Oral Pathol. 1986 Jun;61(6):597-602 [3014420.001]
  • [Cites] Arch Pathol Lab Med. 2001 Jun;125(6):812-5 [11371238.001]
  • (PMID = 18716455.001).
  • [ISSN] 1229-845X
  • [Journal-full-title] Journal of veterinary science
  • [ISO-abbreviation] J. Vet. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2811847
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7. Darling MR, Jackson-Boeters L, Daley TD, Diamandis EP: [Human kallikrein 13 expression in salivary gland tumors]. Int J Biol Markers; 2006 Apr-Jun;21(2):106-110

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Human kallikrein 13 expression in salivary gland tumors].
  • Petraki et al have previously described presence of hK13 in salivary gland tissue, localized to duct epithelia and some acinar cells.
  • The aim of this study was to determine whether hK13 is expressed in salivary gland tissues and salivary gland tumors (both benign and malignant), in order to compare normal with tumor tissues.
  • Pleomorphic adenomas (PA), adenoid cystic carcinomas (ACC), polymorphous low grade adenocarcinomas (PLGA), acinic cell carcinomas (ACI), mucoepidermoid carcinomas (MEC) and adenocarcinomas not otherwise specified (ANOS) of both minor and major salivary glands were examined.
  • The results of this study indicate that most salivary gland tumors show high levels of expression of hK13.
  • Overall, staining in PA was significantly less than that seen in normal salivary gland tissue.
  • PLGA, ACC and ANOS each stained significantly more than normal salivary gland tissue while MEC and ACI did not.
  • Ductal cells and cells lining duct-like structures showed a higher intensity of staining than non-ductal cells in most tumors.
  • Tumors which exhibited only non-ductal cells also exhibited cytoplasmic staining.
  • In conclusion, we demonstrate the high expression of hK13 in several common salivary gland tumors.

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  • (PMID = 28207129.001).
  • [ISSN] 1724-6008
  • [Journal-full-title] The International journal of biological markers
  • [ISO-abbreviation] Int. J. Biol. Markers
  • [Language] ita
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Italy
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8. López Campos D, Campos Bañales ME, López Aguado D: [Primary pleomorphic adenoma (chondroid syringoma) of the external auditory canal. Case report and literature review]. Acta Otorrinolaringol Esp; 2008 May;59(5):252-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary pleomorphic adenoma (chondroid syringoma) of the external auditory canal. Case report and literature review].
  • [Transliterated title] Adenoma pleomórfico primario (siringoma condroide) del conducto auditivo externo. A propósito de un caso y revisión de la literatura.
  • Chondroid syringoma of the external auditory canal is an extremely rare neoplasm, representing the cutaneous counterpart of pleomorphic adenoma of salivary glands.
  • This tumour is thought to derive from the apocrine duct of the folliculo-sebaceous-apocrine unit.
  • We report the case of a 68-year-old male in whom the clinical and radiological examinations showed a well-circumscribed tumour limited to the external auditory canal.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Ear Neoplasms / pathology. Ear, External / pathology

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  • (PMID = 18501163.001).
  • [ISSN] 0001-6519
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 12
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9. Vicioso L, Gallego E, Sanz A: Cutaneous mixed tumor with lipomatous stroma. J Cutan Pathol; 2006 Sep;33 Suppl 2:35-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous mixed tumor with lipomatous stroma.
  • AIM: Mixed tumors are usually composed of two components, one epithelial and the other mesenchymal.
  • To date, only two cases of mixed tumor of the skin have been reported with this type of stroma.
  • METHODS AND RESULTS: We report the case of a 61-year-old man with a mixed tumor situated on the hand, an unusual site for these tumors, with over 90% of the tumor composed of adipose tissue.
  • The tumor was a well-circumscribed, 4.5-cm mass, with the gross appearance of a lipoma.
  • Immunohistochemical study showed findings similar to those seen in classic mixed tumors.
  • CONCLUSION: Together with a few other cases in the skin and parotid gland, this report shows how massive adipose differentiation can arise in a mixed tumor of the skin.
  • [MeSH-major] Adipose Tissue / pathology. Fibroma / pathology. Mixed Tumor, Malignant / pathology. Skin Neoplasms / pathology

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  • (PMID = 16972952.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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10. Sato K, Ueda Y, Shimasaki M, Ozaki M, Nitta N, Chada K, Ishikawa Y, Katsuda S: Pleomorphic adenoma (benign mixed tumor) of the breast: a case report and review of the literature. Pathol Res Pract; 2005;201(4):333-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pleomorphic adenoma (benign mixed tumor) of the breast: a case report and review of the literature.
  • We report a case of pleomorphic adenoma (benign mixed tumor) of the breast, which is an extremely rare location for this tumor.
  • Examination of a 55-year-old woman unexpectedly revealed a mass measuring 0.8 cm in diameter in the subareolar region of the right breast.
  • Excisional biopsy was performed, and the tumor histologically showed pleomorphic adenoma composed of duct epithelial cells, myoepithelial cells, and a myxochondroid matrix.
  • The nuclei of the spindle and myoepithelial cells were immunoreactive for HMGI-C and HMGI(Y) proteins, indicating a histogenesis similar to pleomorphic adenoma of the salivary glands.
  • Sixty-nine cases of this type of tumor arising in the breast have been described previously.
  • Using imaging procedures, the tumor has occasionally been misdiagnosed as malignant clinically and even pathologically in frozen section diagnosis.
  • Careful diagnosis based on paraffin sections is required to avoid unnecessary aggressive surgery, and pathologists should include pleomorphic adenoma in the differential diagnosis of a demarcated, juxtaareolar, small hard mass.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Breast Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Female. HMGA1a Protein / analysis. HMGA2 Protein / analysis. Humans. Immunoenzyme Techniques. In Situ Hybridization, Fluorescence. Middle Aged. Receptors, Estrogen / analysis

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  • (PMID = 15991841.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / HMGA2 Protein; 0 / Receptors, Estrogen; 124544-67-8 / HMGA1a Protein
  • [Number-of-references] 32
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11. Chimona TS, Koutsopoulos AV, Malliotakis P, Nikolidakis A, Skoulakis C, Bizakis JG: Malignant mixed tumor of the nasal cavity. Auris Nasus Larynx; 2006 Mar;33(1):63-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant mixed tumor of the nasal cavity.
  • Parotid gland is the most common location of malignant mixed tumors.
  • Three different subtypes of these tumors exist: carcinoma ex pleomorphic adenoma, carcinosarcoma, and metastasizing mixed tumor.
  • Carcinoma ex-pleomorphic adenoma is by far the most common subtype.
  • Although unusual sites of these tumors have been published, we report an extremely rare case of a malignant mixed tumor located in the nasal cavity.
  • [MeSH-major] Mixed Tumor, Malignant / pathology. Nasal Cavity / pathology. Nose Neoplasms / pathology

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  • (PMID = 16188415.001).
  • [ISSN] 0385-8146
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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12. Sivamani R, Wadhera A, Craig E: Chondroid syringoma: case report and review of the literature. Dermatol Online J; 2006;12(5):8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chondroid syringoma: case report and review of the literature.
  • The lesion had been excised 4 years prior and was diagnosed as chondroid syringoma, but had gradually regrown.
  • Histopathological examination was again consistent with chondroid syringoma, and showed the following:.
  • 1) a chondroid matrix, 2) tubuloalveolar structures lined by a double epithelium, 3) ductal structures lined by a single epithelium, 4) nests of polygonal cells, and 5) the presence of keratinous cysts.
  • Chondroid syringoma is a rare mixed tumor of the skin that was first described by Hirsch and Helwig.
  • Characteristically, it is composed of a proliferation of epithelial cells set in a myxoid and chondroid matrix.
  • Although chondroid syringomas are predominantly benign, malignant forms have been reported.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Facial Neoplasms / pathology. Neoplasm Recurrence, Local / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 16962023.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 24
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13. Kerimoglu U, Aydingoz U, Ozkaya O, Aksu AE, Ergen FB: MRI of a benign chondroid syringoma. Br J Radiol; 2006 Aug;79(944):e59-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] MRI of a benign chondroid syringoma.
  • Chondroid syringoma, also known as mixed tumour of the skin, is a relatively rare, usually benign tumour.
  • A few malignant cases, especially in the lower extremities, have been published, but most of them behave in a benign fashion.
  • A case of a middle-aged woman with surgically proved chondroid syringoma in the pretibial region is presented in this report with MRI and histological findings.
  • Despite rapid growth over a short period of time and a location reportedly associated with malignancy, the histological features were benign.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Sweat Gland Neoplasms / diagnosis

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  • (PMID = 16861320.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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14. Davidson JA, Wong V, Fraser R, Hirsh V: Comparison of primary tumor maximal standardized uptake value (SUV<sub>max</sub>) on preoperative [18F]fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) and histological subtype in patients with non-small cell lung cancer (NSCLC). J Clin Oncol; 2009 May 20;27(15_suppl):7571

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comparison of primary tumor maximal standardized uptake value (SUV<sub>max</sub>) on preoperative [18F]fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) and histological subtype in patients with non-small cell lung cancer (NSCLC).
  • The SUV<sub>max</sub> is a semiquantitative measure of metabolic activity that can distinguish benign from malignant tissue but published data are conflicting regarding its ability to discriminate between major histological subtypes.
  • The SUV<sub>max</sub> values for each histological subtype, along with primary tumor sizes, were compared using F test and t-test analyses.
  • RESULTS: The 15 patients with SC and 5 with LC histology were found to have significantly greater preoperative SUV<sub>max</sub> values than the 19 patients with AC (mean 12.7 and 17.2 vs. 9.4, respectively, P < 0.05), despite the fact that no significant differences in tumor size were observed between histological subtypes.
  • CONCLUSIONS: These data suggest that SC pulmonary tumors have significantly greater uptake on PET/CT than AC tumors.
  • This finding may be helpful in the future when sufficient tissue cannot be obtained for pathological diagnosis or to identify the predominant pathology of mixed tumors.

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  • (PMID = 27963356.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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15. Piulats JM Sr, Nadal M, Martinez-Iniesta M, Puertas S, Gonzalez S, Vidal A, Condom E, Germa-Lluch J, Garcia Del Muro X, Villanueva A: Nude mice model of primary human nonseminoma germ cell tumors to study biology and resistance to cisplatin treatment. J Clin Oncol; 2009 May 20;27(15_suppl):e16143

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nude mice model of primary human nonseminoma germ cell tumors to study biology and resistance to cisplatin treatment.
  • : e16143 Testicular germ cell tumors (TGCTs) are the most common malignancy in young men.
  • Recently, our group has reported the development of a model of human nonseminoma (NSE) after orthotopic nude mice implantation (Piulats et al, Amer Assoc Cancer Res. 2006).
  • Pure and mix NSE anatomies were represented and they reproduce the main histological, genetic and epigenetic characteristics of paired primary tumors.
  • Xenografts mimic distal dissemination patterns and cisplatin (CDDP) tumor behavior responses.
  • We have generated in vivo five tumors showing increased resistance to CDDP by exposition to repetitive cycles and increasing the dose applied through different passages (1 yolk-sac; 1 choriocarcinoma; 2 embrional carcinoma; 1 mix tumor).
  • A shortness time elipse between pasajes was observed for each tumor through CDDP treatments.
  • To confirm increasin resistance, a parallel assay of chemotherapy response was performed between nontreated and CDDP resistant tumors.
  • Whole genome analysis of tour xenografted tumors and their paired CDDP resistant tumor (#3 and #5 passage) were analyzed by CGH NimbeGen arrays using 60 Kb average windows.
  • Few differential genomic changes were identified some of them were consistent across resistant tumors including gain of 9q21.11-9q33.3, 15q23-15q24.1, and 15q26.3 regions and loss of Xp22.33.
  • In one tumour showing strong CDDP resistance compared with its sensitive counterpart it occur in absence of new genomic changes.
  • No changes in the MSI or mutational TP53 status were observed in resisant tumors.
  • Our data suggest that acquisition of tumor resistance to CDDP in TGCTs may proably depend of a combination of different mechanisms, including cromosomal imbalances.

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  • (PMID = 27963427.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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16. Price PM, Asselin M, Koetz B, Dickinson C, Charnley N, Lorigan P, Valle J, Stratford M, Rustin G, Saleem A: A PET imaging study of the vascular disruptive agent OXi4503 to confirm in vivo mechanism of action in a phase I trial. J Clin Oncol; 2009 May 20;27(15_suppl):e14510

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • 2 pts with MM (3.8 & 6.5 mg/m<sup>2</sup>) achieved stable disease.
  • Sustained tumour blood perfusion reduction (50% at 90min & 24hr) was seen in all metastases in the CRC pt treated at 15.4 mg/m<sup>2</sup> after just one dose & resulted in FDG reduction (23% in all 5 mets) & tumor marker response.
  • Doses between 1.9 & 11.0 mg/m<sup>2</sup> produced dose independent reductions in tumour perfusion which were more variable & less marked with 3/8 pts showing a reduction in tumour FDG uptake.
  • The 1pt studied at 28 days (8.5 g/m<sup>2</sup>) showed further sustained reduction in tumour blood flow (40%).
  • Characterisation of the mixed tumour perfusion response at lower doses will aid planning & assessing combination studies.

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  • (PMID = 27963518.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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17. Rauso R, Santagata M, Tartaro G, Filipi M, Colella G: Chondroid syringoma: a rare tumor of orofacial region. Minerva Stomatol; 2009 Jul-Aug;58(7-8):383-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chondroid syringoma: a rare tumor of orofacial region.
  • Chondroid syringoma is a rare tumor arising from the major and minor salivary glands.
  • The incidence of chondroid syringoma is reported to be <0.01% among the primary skin tumors.
  • Eighty percent of the chondroid syringomas are seen in older patients , commonly on head and neck region and mostly on the cheek and nose.
  • The authors report a case discussing the surgical management of a chondroid syringoma and pointing out the importance of including this tumor in the differential diagnosis of small subcutaneous nodules in the head and neck region, in middle-age male patients.
  • [MeSH-major] Adenoma, Pleomorphic. Facial Neoplasms. Mouth Neoplasms

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  • (PMID = 19633639.001).
  • [ISSN] 0026-4970
  • [Journal-full-title] Minerva stomatologica
  • [ISO-abbreviation] Minerva Stomatol
  • [Language] eng; ita
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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18. Constantinescu MB, Chan JB, Cassarino DS: Chondroid syringoma with tyrosine crystals: case report and review of the literature. Am J Dermatopathol; 2010 Apr;32(2):171-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chondroid syringoma with tyrosine crystals: case report and review of the literature.
  • Chondroid syringoma (CS) is a relatively rare cutaneous mixed tumor arising from sweat glands.
  • CSs share morphologic similarities with their salivary gland counterparts, pleomorphic adenomas (benign mixed tumors).
  • Although the presence of tyrosine-rich crystalloids in mixed tumors of the salivary gland is well recognized, to our knowledge, this finding has not been previously described in mixed tumors of the skin.
  • [MeSH-major] Sweat Gland Neoplasms / diagnosis. Sweat Gland Neoplasms / metabolism. Syringoma / diagnosis. Syringoma / metabolism. Tyrosine / metabolism

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  • (PMID = 19851085.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 42HK56048U / Tyrosine
  • [Number-of-references] 29
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19. Villalón G, Monteagudo C, Martín JM, Ramón D, Alonso V, Jordá E: [Chondroid syringoma: a clinical and histological review of eight cases]. Actas Dermosifiliogr; 2006 Nov;97(9):573-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Chondroid syringoma: a clinical and histological review of eight cases].
  • [Transliterated title] Siringoma condroide: revisión clínica e histológica de ocho casos.
  • INTRODUCTION: Chondroid syringoma is a rare skin tumor that presents as a slow growing, indolent lesion, that is more frequent in male adults and is usually benign.
  • MATERIAL AND METHODS: Eight cases diagnosed of chondroid syringoma in our Department in the last eight years were reevaluated clinically and histologically and the epiluminiscence microscopy was used in one of them.
  • All the cases had a myxoid matrix and most also had a chondroid one.
  • DISCUSSION: The chondroid syringoma is usually a small-sized skin tumor, frequently on the head and neck.
  • The microscopic examination of these lesions reveals tubuloalveolar and glandular type structures positioned as islets within a fibroadipose, chondroid, myxoid or hyaline stroma.
  • The final treatment of these tumors is surgical.
  • As a general rule, it is a benign tumor.
  • Some authors have proposed the term of atypical mixed tumor of the skin for those chondroid syringomas with histological traits of malignancy but without evidence of metastasis.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 17173760.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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20. Karnwal A, Pakalapati S, Tzifa K, Raut V: Chondroid syringoma of the external ear canal presenting as a cyst. Kulak Burun Bogaz Ihtis Derg; 2006;16(2):80-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chondroid syringoma of the external ear canal presenting as a cyst.
  • Chondroid syringoma of the external ear canal is a rare, usually firm or polypoid tumor, representing the cutaneous counterpart of pleomorphic adenoma of salivary glands.
  • We report a very rare case of chondroid syringoma in a 40-year-old man who presented with a fluid-containing cyst in the external ear canal.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Ear Neoplasms / diagnosis. Ear, External / pathology

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  • (PMID = 16763421.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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21. Magro G, Floridia F, Geraci G, Marino B: Lipomatous apocrine mixed tumor of the skin: an unusual giant lesion occurring in the breast. J Cutan Pathol; 2009 Jun;36(6):692-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lipomatous apocrine mixed tumor of the skin: an unusual giant lesion occurring in the breast.
  • Cutaneous mixed tumors (MTs), also known as chondroid syringomas, usually arise as small nodules in the head and neck region.
  • We describe an unusual case of a giant MT measuring 9 cm in its greatest diameter, occurring as a slowly growing pedunculated mass on the breast of a 74-year-old woman.
  • Apart this unusual clinical presentation, another intriguing feature of tumor was the histological picture, being composed of an extensive mature fatty stromal component closely intermingling with the epithelial structures.
  • As adipocytes were variable in size and focally showed a lipoblast-like appearance, some tumor areas were reminiscent of a well-differentiated liposarcoma, lipoma-like.
  • Based on the histological features, the term 'lipomatous mixed tumor, apocrine type' was proposed for such a lesion.
  • Histogenetic considerations about the lipomatous stromal component of the tumor are provided.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Breast Neoplasms / pathology. Lipoma / pathology. Neoplasms, Complex and Mixed / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adult. Alzheimer Disease / complications. Female. Humans

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  • (PMID = 19515050.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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22. Hafezi-Bakhtiari S, Al-Habeeb A, Ghazarian D: Benign mixed tumor of the skin, hypercellular variant: a case report. J Cutan Pathol; 2010 Sep;37(9):e46-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign mixed tumor of the skin, hypercellular variant: a case report.
  • Microscopic examination showed a well-circumscribed dermally located tumor composed of ductal elements lined by double to multiple cell layers of bland cuboidal inner cells and elongated spindled outer cells with areas showing cribriform and solid growth patterns.
  • The overall morphology and immunohistochemical profile are that of a benign cutanoues mixed tumor (chondroid syringoma).
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Aged. Biomarkers, Tumor / metabolism. Cell Nucleus / metabolism. Cell Nucleus / pathology. Diagnosis, Differential. Epidermal Cyst / diagnosis. Humans. Immunohistochemistry. Male. Scalp

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  • (PMID = 19614993.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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23. Gündüz K, Demirel S, Heper AO, Günalp I: A rare case of atypical chondroid syringoma of the lower eyelid and review of the literature. Surv Ophthalmol; 2006 May-Jun;51(3):280-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A rare case of atypical chondroid syringoma of the lower eyelid and review of the literature.
  • Histopathologic and immunohistochemical findings were consistent with atypical chondroid syringoma with eccrine differentiation.
  • Chondroid syringoma is a rare skin tumor that occurs, very rarely, in the eyelids, especially the lower eyelid.
  • Only 26 cases of chondroid syringoma in the periorbital area, including our case, have been reported, with various characteristics.
  • Chondroid syringomas are classified as two types, the apocrine type characterized by tubular and cystic branching lumina lined by two layers of epithelial cells, and the eccrine type, which has small tubular lumina lined by a single layer of epithelial cells.
  • The tumor can have benign, atypical, and malignant variants.
  • Our patient had the atypical variant, which is characterized by benign cytological features, as well as the presence of infiltrative margins and/or satellite nodules.
  • Even benign chondroid syringomas, if incompletely excised, can recur with malignant transformation; thus, complete excision and regular follow-up is recommended for all chondroid syringomas.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Eyelid Neoplasms / pathology

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  • (PMID = 16644368.001).
  • [ISSN] 0039-6257
  • [Journal-full-title] Survey of ophthalmology
  • [ISO-abbreviation] Surv Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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24. Dalati T, Hussein MR: Juvenile pleomorphic adenoma of the cheek: a case report and review of literature. Diagn Pathol; 2009;4:32

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Juvenile pleomorphic adenoma of the cheek: a case report and review of literature.
  • Pleomorphic adenoma, also called benign mixed tumor, is the most common tumor of the salivary glands.
  • About 90% of these tumors occur in the parotid gland and 10% in the minor salivary glands.
  • The most common sites of pleomorphic adenoma of the minor salivary glands are the palates followed by lips and cheeks.
  • In children, intraoral pleomorphic adenomas of the cheek are extremely rare with only three cases reported to date.
  • Here we report a case of pleomorphic adenoma of minor salivary glands of the cheek in a 17-year-old girl.
  • To conclude, pleomorphic adenoma should be considered in the differential diagnosis of cheek masses in youngsters.

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  • [Cites] Diagn Pathol. 2009;4:16 [19497106.001]
  • [Cites] J Oral Maxillofac Surg. 2009 Jul;67(7):1539-42 [19531432.001]
  • [Cites] Med Oral Patol Oral Cir Bucal. 2009 Feb;14(2):E73-5 [19179953.001]
  • [Cites] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Jul;104(1):94-100 [17577550.001]
  • [Cites] Int J Oral Maxillofac Surg. 2005 Jul;34(5):528-32 [16053873.001]
  • [Cites] J Craniofac Surg. 2004 Nov;15(6):1056-60 [15547405.001]
  • [Cites] Pathologe. 1999 Mar;20(2):125-9 [10321001.001]
  • [Cites] Oral Surg Oral Med Oral Pathol. 1991 May;71(5):579-82 [1646427.001]
  • [Cites] J Laryngol Otol. 1988 Apr;102(4):382-3 [2838561.001]
  • [Cites] Int J Oral Maxillofac Surg. 1986 Aug;15(4):474-7 [3018105.001]
  • [Cites] Int J Oral Maxillofac Surg. 1986 Dec;15(6):777-9 [3027209.001]
  • [Cites] J Oral Pathol Med. 2004 Jan;33(1):53-5 [14675141.001]
  • [Cites] J Okla Dent Assoc. 2003 Fall;94(2):31-3 [14619233.001]
  • [Cites] Int J Oral Maxillofac Surg. 2002 Jun;31(3):273-5 [12190133.001]
  • [Cites] Otolaryngol Pol. 2002;56(3):385-7 [12162034.001]
  • [Cites] An Otorrinolaringol Ibero Am. 2000;27(4):333-40 [11105334.001]
  • [Cites] Kurume Med J. 2000;47(4):307-23 [11197153.001]
  • [Cites] Hum Pathol. 2000 Apr;31(4):498-503 [10821498.001]
  • (PMID = 19772659.001).
  • [ISSN] 1746-1596
  • [Journal-full-title] Diagnostic pathology
  • [ISO-abbreviation] Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2759908
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25. Khadse P, Prabhash K, Pramesh CS, Chaturvedi P, Shet T: Fine-needle aspiration biopsy of pleural metastases from a carcinosarcoma or true malignant mixed tumor of the parotid gland mimicking a mesothelioma. Diagn Cytopathol; 2009 Sep;37(9):680-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fine-needle aspiration biopsy of pleural metastases from a carcinosarcoma or true malignant mixed tumor of the parotid gland mimicking a mesothelioma.
  • Malignant mixed tumor of the parotid is known to have odd sites for metastases.
  • We describe the fine-needle aspiration cytology (FNAC) findings of pleural metastasis from a malignant mixed tumor misdiagnosed as a mesothelioma on cytology at the onset.A 47-year-old man presented to us with breathlessness and a massive pleural effusion with pleural-based nodules.
  • He had been operated 2 years before for a pleomorphic adenoma of the parotid and had a healthy scar at that site.
  • These cells in contrast to the usual mesothelial cells were not arranged in sheets but rather were huddled in places and formed a pseudoacinar pattern and blended with the myxoid substance.After the diagnosis of a mesothelioma, patient received pemetrexed and cisplatin based chemotherapy with partial response.
  • While on chemotherapy tumor recurred at the primary site in parotid and was confirmed to be a carcinosarcoma on a FNAC and biopsy.To conclude, pleural metastases from a true malignant mixed tumor of the parotid gland can be misdiagnosed as mesothelioma and could occur in the absence of uncontrolled disease at primary site.
  • Both mesotheliomas and pleomorphic adenomas metastatic to the pleura are biphasic tumors, but in a patient with history of pleomorphic adenoma, the latter should be kept as a foremost possibility.
  • Attention to the cytomorphology of tumor cells will also assist in confirming the diagnosis.
  • [MeSH-major] Carcinosarcoma / secondary. Mesothelioma / pathology. Neoplasms, Complex and Mixed / secondary. Parotid Neoplasms / pathology. Pleural Neoplasms / secondary

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  • [Copyright] 2009 Wiley-Liss, Inc.
  • (PMID = 19373913.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Glutamates; 04Q9AIZ7NO / Pemetrexed; 5Z93L87A1R / Guanine; Q20Q21Q62J / Cisplatin
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26. Nowak K: [Carcinosarcoma arising from a preexisting pleomorphic adenoma--true malignant mixed tumor of the parotid gland]. Otolaryngol Pol; 2007;61(6):1024-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Carcinosarcoma arising from a preexisting pleomorphic adenoma--true malignant mixed tumor of the parotid gland].
  • [Transliterated title] Miesakorak rozwijajacy sie w obrebie gruczolaka wielopostaciowego--"prawdziwy" zlośliwy guz mieszany ślinianki przyusznej.
  • Carcinosarcoma (true malignant mixed tumor) is rare in salivary gland neoplasms.
  • Even rarer is a carcinosarcoma arising from a preexisting pleomorphic adenoma.
  • Computed tomography and USG-examination revealed a mass originating from left parotid gland.
  • Clinical and histologic date revealed it had developed from a preexisting pleomorphic adenoma.
  • This tumor seemed to consist of two histogenetically different populations of cells.
  • We also review the literature and dicuss the histogenetic origin of the carcinosarcoma of salivary gland.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Carcinosarcoma / pathology. Mixed Tumor, Malignant / pathology. Parotid Neoplasms / pathology

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  • (PMID = 18546958.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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27. Okuda H, Tei N, Shimizu K, Imazu T, Yoshimura K, Kiyohara H: Chondroid syringoma of the scrotum. Int J Urol; 2008 Oct;15(10):944-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chondroid syringoma of the scrotum.
  • A 70-year-old Japanese man complained of a nodular, non-tender scrotal mass, which had been gradually increasing in size over the last 10 years.
  • Excisional biopsy of the scrotal specimen revealed chondroid syringoma, a very rare benign tumor, more likely to occur in the head and neck region.
  • This is the eighth such case reported, and is an important type of scrotal tumor.
  • [MeSH-major] Adenoma, Pleomorphic. Genital Neoplasms, Male. Scrotum

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  • (PMID = 19138288.001).
  • [ISSN] 1442-2042
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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28. Borman H, Deniz LM, Ertas NM, Arikan U, Colak A: Chondroid syringoma of the hand. Scand J Plast Reconstr Surg Hand Surg; 2009;43(5):291-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chondroid syringoma of the hand.
  • Chondroid syringoma is a rare cutaneous tumour that usually arises in the head and neck region and is rarely seen on the hands; it is rarely malignant at sites other than the head and neck.
  • We present a 56-year-old man with a chondroid syringoma of the hand that clinically resembled a vascular tumour.

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  • (PMID = 19863434.001).
  • [ISSN] 1651-2073
  • [Journal-full-title] Scandinavian journal of plastic and reconstructive surgery and hand surgery
  • [ISO-abbreviation] Scand J Plast Reconstr Surg Hand Surg
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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29. Kazakov DV, Belousova IE, Bisceglia M, Calonje E, Emberger M, Grayson W, Hantschke M, Kempf W, Kutzner H, Michal M, Spagnolo DV, Virolainen S, Zelger B: Apocrine mixed tumor of the skin ("mixed tumor of the folliculosebaceous-apocrine complex"). Spectrum of differentiations and metaplastic changes in the epithelial, myoepithelial, and stromal components based on a histopathologic study of 244 cases. J Am Acad Dermatol; 2007 Sep;57(3):467-83
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Apocrine mixed tumor of the skin ("mixed tumor of the folliculosebaceous-apocrine complex"). Spectrum of differentiations and metaplastic changes in the epithelial, myoepithelial, and stromal components based on a histopathologic study of 244 cases.
  • BACKGROUND: A systematic analysis of the entire spectrum of various forms of differentiation and metaplastic epiphenomena in cutaneous apocrine mixed tumor (AMT) has never been performed.
  • OBJECTIVE: The purpose of our study was to study a large number of cutaneous mixed tumors so as to fully characterize the entire spectrum of differentiations and metaplastic changes that may occur in the epithelial, myoepithelial, and stromal components of AMT.
  • Stromal alterations included chondroid metaplasia, osseous metaplasia, and adipose metaplasia.
  • We propose that the most appropriate name for these lesions is "mixed tumor of the folliculosebaceous-apocrine complex. "
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Apocrine Glands. Skin Neoplasms / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 17707152.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 104
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30. Dubb M, Michelow P: Cytologic features of chondroid syringoma in fine needle aspiration biopsies: a report of 3 cases. Acta Cytol; 2010 Mar-Apr;54(2):183-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytologic features of chondroid syringoma in fine needle aspiration biopsies: a report of 3 cases.
  • However, most clinicians prefer to diagnose suspected skin tumors by excisional biopsy as they are easily accessible, with the result that benign skin adnexal tumors are rarely encountered on FNA, often leading to misdiagnosis and mismanagement of patients.
  • We describe the cytologic features of chondroid syringoma in 3 cases in order to facilitate cytologic diagnosis of this lesion.
  • CASES: Three patients each presented with a mass lesion in the head and neck region and on FNA were diagnosed as having chondroid syringomas.
  • CONCLUSION: Knowledge of the cytologic features of chondroid syringoma will allow definitive diagnosis and correct management of the patient.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Salivary Gland Neoplasms / diagnosis

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  • (PMID = 20391975.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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31. Qureshi A: True malignant mixed tumor of parotid. J Coll Physicians Surg Pak; 2007 Nov;17(11):697-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] True malignant mixed tumor of parotid.
  • Carcinosarcoma is a rare malignant neoplasm of salivary glands that manifests both carcinomatous and sarcomatous components.
  • Specimen of a recurrent parotid tumor of a 55-year-old male was received for histopathology.
  • Diagnosis of a biphasic malignant neoplasm was made.
  • Morphology and immunohistochemical profile were consistent with carcinosarcoma i.e. true malignant mixed tumor.

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  • (PMID = 18070582.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Pakistan
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32. Mebazaa A, Trabelsi S, Denguezli M, Sriha B, Belajouza C, Nouira R: Chondroid syringoma of the arm: an unusual localization. Dermatol Online J; 2006;12(1):14
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chondroid syringoma of the arm: an unusual localization.
  • Chondroid syringoma (CS) is an uncommon, benign, sweat-gland tumor.
  • We present a case of a CS located in the right arm of a 43-year-old woman.
  • This tumor developed slowly over 8 years.
  • The diagnosis of CS was made by histopathological examination; it showed an abundant chondroid stroma intermingled with a fibro-adipoid tissue.
  • There was no recurrence after total excision of the tumor with a 2-year followup.
  • The unusual localization of chondroid syringoma made an accurate preoperative diagnosis difficult and diagnosis was achieved only by microscopy.
  • Surgical tumor excision remains the best therapeutic option to avoid relapses of this tumor.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Arm. Sweat Gland Neoplasms / pathology

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  • (PMID = 16638382.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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33. Stomeo F, Rocca PC, Bozzo C, Bianchini C, Meloni F, Pastore A: Laryngeal true malignant mixed tumor. Head Neck; 2009 Apr;31(4):556-60

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laryngeal true malignant mixed tumor.
  • BACKGROUND: True malignant mixed tumor, also known as carcinosarcoma, is a salivary gland type malignant neoplasm, which is extremely rare, and only a few cases arising in the larynx have been previously reported.
  • METHODS AND RESULTS: We report a case of true malignant mixed tumor arising in the larynx of a 65-year-old woman successfully treated with surgery.
  • Histologically, the neoplasm was composed of variably mixed, neoplastic glandular, spindle, and chondroid tissues.
  • CONCLUSION: These results strengthen the hypothesis that these neoplasms may develop from a divergent differentiation of a totipotent, myoepithelial precursor cell.
  • [MeSH-major] Carcinosarcoma / pathology. Laryngeal Neoplasms / pathology. Mixed Tumor, Malignant / pathology

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  • (PMID = 18972426.001).
  • [ISSN] 1097-0347
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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34. Biernat W: Lipomatous mixed tumor of the skin. Am J Dermatopathol; 2008 Jun;30(3):284-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lipomatous mixed tumor of the skin.
  • An unusual tumor of the neck in a 56-year-old female is reported.
  • The tumor was composed of tubules and small cords of epithelial cells dispersed in the fibromyxoid and adipose stroma.
  • At the periphery, the tumor was not encapsulated and its border was intermingled with the subcutaneous fat.
  • Lack of decapitation secretion and the absence of long tubules suggested an eccrine origin; however, in some of the tumor areas, the cells showed brightly eosinophilic copious cytoplasm that may indicate an apocrine differentiation.
  • As an area of chondroid metaplasia was identified, the diagnosis of a mixed tumor was rendered.
  • This unusual type of skin adnexal neoplasm with unique relation of the epithelial component to the surrounding adipose tissue requires differentiation with the primary cutaneous and metastatic carcinomas.
  • [MeSH-major] Adipose Tissue / pathology. Head and Neck Neoplasms / diagnosis. Lipoma / pathology. Neoplasms, Complex and Mixed / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Adipocytes / pathology. Biomarkers, Tumor / analysis. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Keratins / analysis. Middle Aged. Neoplasm Metastasis / diagnosis

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  • (PMID = 18496435.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 68238-35-7 / Keratins
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35. Turhan-Haktanir N, Sahin O, Bukulmez A, Demir Y: Chondroid syringoma in a child. Pediatr Dermatol; 2007 Sep-Oct;24(5):505-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chondroid syringoma in a child.
  • Chondroid syringoma is a myxoid tumor of the skin, which has a reported incidence of <0.01% among primary skin tumors.
  • The majority of these tumors occur in the head and neck regions of adult males.
  • We present the first instance of chondroid syringoma in a child, which, to the best of our knowledge, has not been reported previously in the English language literature.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Nose Neoplasms / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 17958797.001).
  • [ISSN] 1525-1470
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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36. Nath AK, Kumari R, Thappa DM: Eccrine spiradenoma with chondroid syringoma in Blaschkoid distribution. Indian J Dermatol Venereol Leprol; 2009 Nov-Dec;75(6):600-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Eccrine spiradenoma with chondroid syringoma in Blaschkoid distribution.
  • It may be associated with foci of various other appendageal tumors.
  • Histopathology revealed dermal lobules of ES with smaller foci of chondroid syringoma.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Adenoma, Sweat Gland / pathology. Neoplasms, Multiple Primary / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 19915242.001).
  • [ISSN] 0973-3922
  • [Journal-full-title] Indian journal of dermatology, venereology and leprology
  • [ISO-abbreviation] Indian J Dermatol Venereol Leprol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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37. Tokyol C, Aktepe F, Yavas BD, Yildiz H, Aycicek A: Chondroid syringoma: a case report. Acta Cytol; 2010 Sep-Oct;54(5 Suppl):973-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chondroid syringoma: a case report.
  • BACKGROUND: Chondroid syringoma is a benign skin adnexal tumor.
  • The reported incidence of chondroid syringoma among primary skin tumors is low and has been reported at 0.01-0.098%.
  • CASE: A 57-year-old woman presented with a 10-year history of a slowly growing lump on her philtrum.
  • A diagnosis of benign appendageal tumor of the skin was made.
  • Surgical excision of tumor was done.
  • Histopathologic examination was consistent with chondroid syringoma.
  • CONCLUSION: Chondroid syringoma should be included in the differential diagnosis of a slowly growing nodule on the head or neck.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Lip Neoplasms / pathology

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  • (PMID = 21053580.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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38. Kasashima S, Hiroshi M, Toshinori M, Yoshio O: Lipomatous mixed tumor with follicular differentiation of the skin. J Cutan Pathol; 2006 May;33(5):389-94
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lipomatous mixed tumor with follicular differentiation of the skin.
  • A very rare case of cutaneous mixed tumor with numerous adipose tissue and hair follicular structures in a 67-year-old Japanese male was reported.
  • A well-circumscribed tumor was in the subcutaneous tissue of the cheek and far from the parotid gland.
  • Histologically, the tumor consisted of an admixture of the adipose tissue, fibromyxoid tissue with spindle cells, and branching tubular structures.
  • Outer layers of ductal epithelial cells and single spindle cells were often in a transition, likely as typical mixed tumor.
  • No chondroid stroma was seen.
  • To our knowledge, this tumor is the first case of a lipomatous mixed tumor with hair follicular differentiation.
  • The case indicates an additional wide spectrum of histologic appearances of cutaneous mixed tumor.
  • [MeSH-major] Adipose Tissue / pathology. Hair Follicle / pathology. Mixed Tumor, Malignant / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Aged. Apocrine Glands / pathology. Biomarkers, Tumor / analysis. Hair Diseases / metabolism. Hair Diseases / pathology. Humans. Immunohistochemistry. Male

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  • (PMID = 16640549.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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39. Sirivella S, Gielchinsky I: Chondroid syringoma: a rare tumor of the chest wall. Ann Thorac Surg; 2010 Mar;89(3):983-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chondroid syringoma: a rare tumor of the chest wall.
  • Chondroid syringoma, an uncommon, slow-growing, benign, sweat-gland tumor located on the upper right chest wall of a 66-year-old woman is presented.
  • This skin adenexal tumor is typically located on the head and neck region.
  • The unusual location of chondroid syringoma made an accurate preoperative diagnosis difficult, and diagnosis was achieved only by excisional biopsy and histopathologic examination.
  • Total surgical excision remains the best therapeutic option to avoid tumor recurrence and close follow-up is recommended because of a rare possibility of malignant transformation and visceral metastases.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Sweat Gland Neoplasms / diagnosis

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  • [Copyright] 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20172178.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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40. Choudhury M, Agarwal C, Aggarwal M, Pathania OP, Goel N: Clinicopathological profile of an unusual case of chondroid syringoma: a case report. Indian J Pathol Microbiol; 2007 Apr;50(2):349-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinicopathological profile of an unusual case of chondroid syringoma: a case report.
  • Chondroid syringoma or mixed tumor of the skin is an uncommon tumor that typically presents as small, solitary, slow growing, firm, subcutaneous or intracutaneous nodule.
  • FNAC and excision biopsy revealed benign chondroid syringoma.
  • This is a rare case of chondroid syringoma exhibiting large size, multiplicity and unusual locations in flank, chest wall and thigh.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 17883069.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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41. Bekler H, Gokce A, Beyzadeoglu T: Chondroid syringoma of the hand: a rare localization. Handchir Mikrochir Plast Chir; 2007 Dec;39(6):430-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chondroid syringoma of the hand: a rare localization.
  • Chondroid syringoma is a rare benign neoplasm of the sweat glands that usually occurs in the head and neck region.
  • We describe a 18-year-old male patient with a benign chondroid syringoma that occurred at an unusual site, leading to compression symptoms of the ulnar nerve causing symptoms at the hypothenar region of the right hand.
  • Although it is a rare tumor at an unusual site, it should be included in the differential diagnosis of the hand tumors.
  • [MeSH-major] Adenoma, Pleomorphic / surgery. Soft Tissue Neoplasms / surgery

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  • (PMID = 18058676.001).
  • [ISSN] 0722-1819
  • [Journal-full-title] Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Mikrochirurgie der Peripheren Nerven und Gefässe : Organ der Vereinigung der Deutschen Plastischen Chirurgen
  • [ISO-abbreviation] Handchir Mikrochir Plast Chir
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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42. Kumar B: Chondroid syringoma diagnosed by fine needle aspiration cytology. Diagn Cytopathol; 2010 Jan;38(1):38-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chondroid syringoma diagnosed by fine needle aspiration cytology.
  • Chondroid syringoma is a rare benign skin adnexal tumor of eccrine/apocrine origin affecting commonly the head and neck region.
  • It used to be previously called as mixed tumor of skin because of the presence of both the epithelial and mesenchymal components.
  • There are only few case reports describing the fine needle aspiration cytologic features of chondroid syringoma for diagnosis.
  • On the basis of these cytologic features, a diagnosis of chondroid syringoma was made.
  • We concluded that Chondroid syringoma may be considered as a rare differential diagnosis in the swelling of head and neck region and the diagnosis can be easily confirmed or ruled out by means of fine needle aspiration cytology.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Adenoma, Pleomorphic / pathology. Salivary Gland Neoplasms / diagnosis. Salivary Gland Neoplasms / pathology

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  • [Copyright] (c) 2009 Wiley-Liss, Inc.
  • (PMID = 19693940.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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43. Nistal M, Yébenes-Gregorio L, Esteban-Rodríguez I, Bernáldez R, Regadera J: Malignant mixed tumor of the larynx. Head Neck; 2005 Feb;27(2):166-70

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant mixed tumor of the larynx.
  • BACKGROUND: Malignant mixed tumor of the larynx is a very rare neoplasm; only five cases have been reported, three in the English-language literature.
  • METHODS: We report the case of a 69-year-old man with a 2-month history of hoarseness and a left laterocervical palpable mass.
  • The tumor involved the glottic and subglottic regions and thyroid cartilage and extended to the anterior side of the larynx.
  • Microscopically, the tumor was composed of three cellular types: epithelial cells, chondrocytes, and spindle cells.
  • The tumor metastasized to a cervical lymph node, with the three described components.
  • CONCLUSIONS: The lesion in this case was considered to be a malignant mixed tumor.
  • Differences between this tumor and that of laryngeal chondrosarcoma are discussed.
  • [MeSH-major] Laryngeal Neoplasms / pathology. Mixed Tumor, Malignant / pathology

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  • [Copyright] 2005 Wiley Periodicals, Inc.
  • (PMID = 15641103.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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44. Lin WC, Li CS, Lin CK, Hsu HH, Chang TH, Chen TY, Huang GS: Atypical pulmonary metastases from a true malignant mixed tumor of the parotid gland. Korean J Radiol; 2009 Mar-Apr;10(2):202-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Atypical pulmonary metastases from a true malignant mixed tumor of the parotid gland.
  • A 58-year-old male patient presented with a recurrent true malignant mixed tumor of the parotid gland.
  • This abnormality was confirmed to be the result of a metastatic true malignant mixed tumor by using CT-guided biopsy.
  • The current case demonstrated an extremely rare example of atypical pulmonary metastases from a true malignant mixed tumor of the parotid gland showing an air-space pattern and calcification.
  • [MeSH-major] Lung Neoplasms / secondary. Mixed Tumor, Malignant / pathology. Parotid Neoplasms / pathology

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  • [Cites] Arch Pathol Lab Med. 2001 Jun;125(6):812-5 [11371238.001]
  • [Cites] Histopathology. 1980 Sep;4(5):567-77 [6253382.001]
  • [Cites] Cancer. 1981 Jun 1;47(11):2595-602 [7260854.001]
  • [Cites] Ann Otol Rhinol Laryngol. 1982 May-Jun;91(3 Pt 1):342-3 [6284009.001]
  • [Cites] Pathol Annu. 1993;28 Pt 1:279-328 [8380049.001]
  • [Cites] Radiographics. 2001 Mar-Apr;21(2):403-17 [11259704.001]
  • [Cites] Oral Oncol. 2006 Mar;42(3):323-6 [16253544.001]
  • [Cites] Ann Otol Rhinol Laryngol. 2007 Sep;116(9):702-4 [17926594.001]
  • [Cites] Pediatr Radiol. 2008 May;38(5):551-8 [18246342.001]
  • [Cites] J Comput Assist Tomogr. 1996 Mar-Apr;20(2):300-4 [8606242.001]
  • [CommentIn] Korean J Radiol. 2014 May-Jun;15(3):399-400 [24843247.001]
  • (PMID = 19270869.001).
  • [ISSN] 2005-8330
  • [Journal-full-title] Korean journal of radiology
  • [ISO-abbreviation] Korean J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2651446
  • [Keywords] NOTNLM ; Atypical pulmonary metastases / Computed tomography (CT) / Parotid gland, true malignant mixed tumor
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45. Li ZL, Sun D, Kong CZ: [Diagnosis and treatment for the corticomedullary mixed tumor of adrenal gland]. Zhonghua Wai Ke Za Zhi; 2009 Aug 15;47(16):1239-41
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Diagnosis and treatment for the corticomedullary mixed tumor of adrenal gland].
  • OBJECTIVE: To study and summarize the diagnosis and treatment for the corticomedullary mixed tumor of adrenal gland.
  • METHODS: The clinical data of 25 cases of adrenal corticomedullary mixed tumor from January 2000 to April 2008 were analyzed retrospectively, which including 9 males and 16 females.
  • All of the cases had blood pressure fluctuation during dissection of the adrenal tumors, with the highest blood pressure reached to 230/140 mm Hg (1 mm Hg = 0.133 kPa).
  • Postoperative histopathological study revealed that the pathological changes was corticomedullary mixed tumor of adrenal gland, which was supported by immunohistochemical study.
  • CONCLUSIONS: In cases with complex phenomenon that can't explain with single cortical or medullary changes, it must beware of the mixed pathological changes in adrenal gland.
  • [MeSH-major] Adrenal Gland Neoplasms / diagnosis. Adrenal Gland Neoplasms / surgery

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  • (PMID = 19781172.001).
  • [ISSN] 0529-5815
  • [Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]
  • [ISO-abbreviation] Zhonghua Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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46. Kaushik V, Bhalla RK, Nicholson C, de Carpentier JP: The chondroid syringoma: report of a case arising from the external auditory canal. Eur Arch Otorhinolaryngol; 2005 Oct;262(10):868-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The chondroid syringoma: report of a case arising from the external auditory canal.
  • Chondroid syringoma is an uncommon, benign skin adnexal tumour.
  • A rare case of chondroid syringoma arising from the external auditory canal is reported.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Ear Canal. Ear Neoplasms / diagnosis. Sweat Gland Neoplasms / diagnosis

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  • (PMID = 15739085.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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47. Skoro M, Ostović KT, Cikara I, Müller D, Novak NP, Virag M: Fine needle aspiration cytology of chondroid syringoma. Coll Antropol; 2010 Jun;34(2):687-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fine needle aspiration cytology of chondroid syringoma.
  • Chondroid syringoma (CS) is a rare, benign, appendageal tumor with diagnostic feature of myxochondroid stroma supporting eccrine and apocrine epithelial structures.
  • It should be included in the differential diagnosis of cutaneous head and neck tumors, especially in middle-aged men.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Head and Neck Neoplasms / pathology

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  • (PMID = 20698155.001).
  • [ISSN] 0350-6134
  • [Journal-full-title] Collegium antropologicum
  • [ISO-abbreviation] Coll Antropol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Croatia
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48. Laspas F, Roussakis A, Papadopoulos S, Fanariotis I, Kritikos N, Kehagias D: Mixed tumor of the vagina: sonographic and magnetic resonance imaging findings. Ultrasound Obstet Gynecol; 2010 May;35(5):617-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mixed tumor of the vagina: sonographic and magnetic resonance imaging findings.
  • Mixed tumor of the vagina is a rare benign neoplasm that is composed of epithelial and mesenchymal cells.
  • The majority of tumors are asymptomatic and simple tumor excision is curative.

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  • [Copyright] Copyright 2009 ISUOG. Published by John Wiley & Sons, Ltd.
  • (PMID = 20069660.001).
  • [ISSN] 1469-0705
  • [Journal-full-title] Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology
  • [ISO-abbreviation] Ultrasound Obstet Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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49. Urbaniec P, Namysłowski G, Lange D, Urbaniec N: [Pleomorphic adenoma of the nasal septum]. Otolaryngol Pol; 2005;59(3):425-7
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  • [Title] [Pleomorphic adenoma of the nasal septum].
  • [Transliterated title] Gruczolak wielopostaciowy przegrody nosa.
  • The authors described the case of mixed salivary gland tumour in the nasal septum.
  • [MeSH-major] Adenoma, Pleomorphic. Nasal Septum / pathology. Nose Neoplasms

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  • (PMID = 16117402.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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50. Kakitsubata Y, Theodorou SJ, Theodorou DJ, Nakahara M, Yuki Y, Yokouchi T: Giant chondroid syringoma presenting as a growing subcutaneous mass in the upper arm: MRI findings with pathologic correlation. Joint Bone Spine; 2009 Dec;76(6):711-4
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  • [Title] Giant chondroid syringoma presenting as a growing subcutaneous mass in the upper arm: MRI findings with pathologic correlation.
  • Chondroid syringoma of skin is a rare type of soft tissue tumor originating from the sweat glands.
  • We report a documented case of giant chondroid syringoma occurring in the upper arm, which developed over the course of one year.
  • The radiographic, sonographic, MR imaging, gross pathologic, and histologic findings of the tumor are described.
  • Because the clinical suggestion of such a tumor was low, we present the imaging appearances of chondroid syringoma that could be used to make a presumptive diagnosis, and discuss the many entertained differential diagnostic possibilities.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Magnetic Resonance Imaging / methods. Sweat Gland Neoplasms / diagnosis

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  • (PMID = 19793672.001).
  • [ISSN] 1778-7254
  • [Journal-full-title] Joint, bone, spine : revue du rhumatisme
  • [ISO-abbreviation] Joint Bone Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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51. Akbulut M, Zekioglu O, Terek MC, Ozdemir N: Lipoadenofibroma of the endometrium: a rare variant of benign mullerian mixed tumor. Arch Gynecol Obstet; 2008 Sep;278(3):283-6

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  • [Title] Lipoadenofibroma of the endometrium: a rare variant of benign mullerian mixed tumor.
  • OBJECTIVE: Adenofibroma is a form of mixed mesodermal tumor in which epithelial and stromal components are benign, and usually arises in the endometrium of postmenopausal women.
  • CONCLUSION: We suggest that uterine adenofibromas with lipomatous areas belong to the family of mixed tumor of Mullerian origin.
  • [MeSH-major] Adenofibroma / pathology. Endometrial Neoplasms / pathology. Mixed Tumor, Mullerian / pathology

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  • (PMID = 18236054.001).
  • [ISSN] 1432-0711
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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52. Kuroda N, Moriki T, Oguri H, Maeda N, Toi M, Miyazaki E, Hiroi M, Fukaya T, Enzan H: Malignant müllerian mixed tumor (carcinosarcoma) of the fallopian tube: an immunohistochemical study of neoplastic cells. APMIS; 2005 Sep;113(9):643-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant müllerian mixed tumor (carcinosarcoma) of the fallopian tube: an immunohistochemical study of neoplastic cells.
  • Histologically, proliferation of undifferentiated neoplastic cells with marked cytological atypia predominated in the tumor.
  • A diagnosis of malignant müllerian mixed tumor (MMMT) was made.

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  • (PMID = 16218942.001).
  • [ISSN] 0903-4641
  • [Journal-full-title] APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
  • [ISO-abbreviation] APMIS
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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53. Steele NP, Wenig BM, Sessions RB: A case of pleomorphic adenoma of the parotid gland metastasizing to a mediastinal lymph node. Am J Otolaryngol; 2007 Mar-Apr;28(2):130-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of pleomorphic adenoma of the parotid gland metastasizing to a mediastinal lymph node.
  • OBJECTIVE: Pleomorphic adenomas are the most common salivary gland tumors and are typically cured with complete surgical excision.
  • There are rare reports, however, in which these histologically benign tumors have inexplicably metastasized to distant sites.
  • We present a case of a patient who presented, 27 years after excision of a parotid pleomorphic adenoma, with a recurrence in the parotid bed and a mediastinal metastasis.
  • METHODS: A 43-year-old woman presented with a mass in the right parotid bed 27 years after excision of a pleomorphic adenoma of the parotid.
  • The patient's presentation, workup, and final diagnosis of benign metastasizing pleomorphic adenoma will be discussed, along with a pertinent review of the literature.
  • RESULTS: A diagnosis of recurrent pleomorphic adenoma was made from a fine needle aspiration biopsy of the right parotid mass.
  • On subsequent computed tomographic scan, chest images revealed an incidental left mediastinal mass, which also proved to be a pleomorphic adenoma on computed tomography-guided fine needle aspiration biopsy.
  • Examination of the pathology specimens confirmed a diagnosis of pleomorphic adenoma in both the parotid bed and the mediastinum.
  • No histologic characteristics of malignancy were seen in either specimen; therefore, a diagnosis of benign metastasizing mixed tumor was rendered.
  • CONCLUSION: Benign metastasizing pleomorphic adenoma is a rare and controversial but distinct clinical entity.
  • Although the definition of the term benign precludes metastatic disease, these tumors do not demonstrate any malignant features yet metastasize to distant sites.
  • It remains to be determined whether these benign metastasizing pleomorphic adenomas are really low-grade salivary malignancies.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Parotid Neoplasms / pathology

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  • (PMID = 17362821.001).
  • [ISSN] 0196-0709
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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54. Shono Y, Tsuji T, Horiuchi T, Nakai T, Uchiyama K, Nakatani Y, Kinoshita H, Tabuse K, Yamaue H: Nonhepatocytic malignant mixed tumor of the liver in adults: report of a long surviving case. Int Surg; 2008 Jan-Feb;93(1):55-8
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  • [Title] Nonhepatocytic malignant mixed tumor of the liver in adults: report of a long surviving case.
  • A primary nonhepatocytic malignant mixed tumor in the liver contains both epithelial and mesenchymal components, and the incidence in adults is extremely rare.
  • Abdominal imaging studies revealed a huge cystic tumor with a mural nodule in the right lobe.
  • The patient is still alive 11 years after surgery, and to our knowledge is the longest surviving patient with a primary nonhepatocytic malignant mixed primary tumor of the liver.
  • [MeSH-major] Cystadenocarcinoma / pathology. Liver Neoplasms / pathology. Mixed Tumor, Malignant / pathology

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  • (PMID = 18543556.001).
  • [ISSN] 0020-8868
  • [Journal-full-title] International surgery
  • [ISO-abbreviation] Int Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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55. Mortelé KJ, Peters HE, Odze RD, Glickman JN, Jajoo K, Banks PA: An unusual mixed tumor of the pancreas: sonographic and MDCT features. JOP; 2009;10(2):204-8
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  • [Title] An unusual mixed tumor of the pancreas: sonographic and MDCT features.
  • CONTEXT: Mixed tumors of the pancreas are exceedingly rare.
  • Right upper quadrant ultrasound and multidetector-row CT scan showed a well-defined unilocular cystic tumor located in the head of the pancreas and surrounded, in part, by a hypervascular solid mass.
  • CONCLUSION: Although mixed exocrine/endocrine pancreatic tumors have been described previously, to the best of our knowledge, this is the first case of a pancreatic mixed intraductal papillary mucinous neoplasm/endocrine tumor with illustration of its ultrasound and CT features.
  • [MeSH-major] Mixed Tumor, Malignant / pathology. Pancreatic Neoplasms / pathology

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  • (PMID = 19287120.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / MUC2 protein, human; 0 / Mucin-2; 0 / Synaptophysin
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56. Kajor M, Gierek T, Markowski J, Pajak J: Schwannomalike mixed tumor of the parotid gland: a case report. Acta Cytol; 2006 Sep-Oct;50(5):529-30

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Schwannomalike mixed tumor of the parotid gland: a case report.
  • BACKGROUND: Schwannomalike mixed tumor is a rare benign tumor of the parotid glands.
  • CASE: A 75-year-old woman presented with a tumor 3 cm in diameter localized in her left parotid gland.
  • Morphologic examinations were performed.
  • CONCLUSION: FNA cytology was very useful in the diagnosis of this rare tumor of the parotid gland.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Neurilemmoma / diagnosis. Parotid Gland / pathology. Parotid Neoplasms / diagnosis
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Biomarkers, Tumor / metabolism. Biopsy, Fine-Needle. Diagnosis, Differential. Digestive System Surgical Procedures. Epithelial Cells / metabolism. Epithelial Cells / pathology. Female. Humans. Immunohistochemistry. Predictive Value of Tests. Schwann Cells / metabolism. Schwann Cells / pathology. Treatment Outcome

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  • (PMID = 17017438.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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57. Baran JL, Hoang MP: Apocrine mixed tumor of the skin with a prominent pilomatricomal component. J Cutan Pathol; 2009 Aug;36(8):882-6
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  • [Title] Apocrine mixed tumor of the skin with a prominent pilomatricomal component.
  • Pilomatrical differentiation within an apocrine mixed tumor (AMT) when present is only focal and has not been reported to be extensive.
  • Histologic sections revealed, underneath a neurofibroma, a well-circumscribed tumor composed of nodules of branching epithelial elements and occasional keratinous cysts within a myxoid and lipomatous stroma.
  • In approximately 50% of the tumor, eosinophilic ghost/shadow cells associated with a foreign body giant cell reaction formed a nodule resembling a pilomatricoma.
  • The presence of follicular and apocrine differentiation within our tumor reinforces the common embryologic derivation of these elements.
  • [MeSH-major] Apocrine Glands / pathology. Facial Neoplasms / pathology. Mixed Tumor, Malignant / pathology. Pilomatrixoma / pathology. Skin Neoplasms / pathology

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  • (PMID = 19586498.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Neoplasm Proteins
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58. Mieno H, Kuroda K, Tajima S: Bone morphogenetic protein-mediated type II collagen expression in pilomatricoma and cutaneous mixed tumor. J Cutan Pathol; 2005 Mar;32(3):206-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bone morphogenetic protein-mediated type II collagen expression in pilomatricoma and cutaneous mixed tumor.
  • BACKGROUND: We have previously reported that type II collagen deposition in overlying dermo-epidermal junction (DEJ) of pilomatricoma is mediated by bone morphogenetic protein 2/4 (BMP 2/4) expressed by shadow cells (SCs) of pilomatricoma.
  • OBJECTIVE: This time, we studied the expression of type II collagen and BMP in a large number of cases of pilomatricoma and extended our study to cutaneous mixed tumor (CMT).
  • RESULTS: We found type II collagen deposition in the overlying DEJ (16 of 50 cases) and in the SCs (19/50) of pilomatricoma.
  • The number of case of type II collagen deposition in DEJ (DEJ(+)) and in SCs (SC(+)) of pilomatricoma correlated to the chronological stage of pilomatricoma.
  • We also found type II collagen deposition in overlying DEJ (two of 11) and in the stromal chondroid tissue (four of 11) of CMT.
  • CONCLUSIONS: The expression of type II collagen in pilomatricoma is dependent upon the chronological stage of pilomatricoma.
  • Type II collagen expression in the overlying DEJ and chondroid matrix in CMT may be induced by BMP via the same mechanism as in pilomatricoma.
  • [MeSH-major] Bone Morphogenetic Proteins / metabolism. Collagen Type II / metabolism. Hair Diseases / metabolism. Mixed Tumor, Malignant / metabolism. Pilomatrixoma / metabolism. Skin Neoplasms / metabolism
  • [MeSH-minor] Adolescent. Adult. Aged. Biomarkers, Tumor / metabolism. Child. Dermis / metabolism. Dermis / pathology. Epidermis / metabolism. Epidermis / pathology. Female. Humans. Immunohistochemistry. Intercellular Junctions / metabolism. Intercellular Junctions / pathology. Male. Middle Aged

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  • (PMID = 15701082.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Bone Morphogenetic Proteins; 0 / Collagen Type II
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59. Kuroda N, Inui Y, Ohara M, Hirouchi T, Mizuno K, Kubo A, Hayashi Y, Enzan H, Lee GH: Hyaline globule-like structures in undifferentiated sarcoma cells of malignant müllerian mixed tumor of the fallopian tube. Med Mol Morphol; 2007 Mar;40(1):46-9
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  • [Title] Hyaline globule-like structures in undifferentiated sarcoma cells of malignant müllerian mixed tumor of the fallopian tube.
  • Malignant müllerian mixed tumors (MMMTs) of the fallopian tube are very rare neoplasms, and we present such a case with unusual findings here.
  • At the time of operation, the main tumor was present predominantly in the fallopian tube.
  • Microscopically, the tumor consisted of carcinoma and sarcoma components.
  • [MeSH-major] Adenocarcinoma / pathology. Fallopian Tube Neoplasms / pathology. Hyalin / ultrastructure. Mixed Tumor, Mullerian / pathology. Rhabdomyosarcoma / pathology
  • [MeSH-minor] Cell Differentiation. Cytoplasm / metabolism. Cytoplasm / ultrastructure. Eosine Yellowish-(YS) / metabolism. Fallopian Tubes / pathology. Female. Humans. Lysosomes / metabolism. Lysosomes / ultrastructure. Microscopy, Electron, Transmission. Middle Aged. Mixed Tumor, Malignant / pathology. Mixed Tumor, Malignant / ultrastructure

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  • (PMID = 17384990.001).
  • [ISSN] 1860-1480
  • [Journal-full-title] Medical molecular morphology
  • [ISO-abbreviation] Med Mol Morphol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] TDQ283MPCW / Eosine Yellowish-(YS)
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60. Hong KH, Yang YS: Intraoral approach for the treatment of submandibular salivary gland mixed tumors. Oral Oncol; 2008 May;44(5):491-5
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  • [Title] Intraoral approach for the treatment of submandibular salivary gland mixed tumors.
  • Pleomorphic adenoma represents a most common benign neoplasm of major salivary glands.
  • Most occurrences of this benign tumor in the submandibular gland have been treated surgically without difficulty via transcervical approach.
  • In this study, we introduced the intraoral approach for the removal of the submandibular mixed tumor.
  • In total, 12 cases of pleomorphic adenoma of the submandibular gland were treated via intraoral approach.
  • During surgery the tumor and submandibular gland are easily dissected from surrounding tissue and removed through intraoral incision.
  • All patients were followed up for the recurrence of the tumor from 20 months to 10 years.
  • One patient showed a tumor recurrence at the early stage of this approach.
  • We propose that the benign mixed tumor of the submandibular gland could be removed easily via intraoral route without an external scar or nerve injury.
  • [MeSH-major] Adenoma, Pleomorphic / surgery. Postoperative Complications / prevention & control. Submandibular Gland / surgery. Submandibular Gland Neoplasms / surgery

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  • (PMID = 17827052.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] England
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61. Tamiolakis D, Chimona TS, Georgiou G, Proimos E, Nikolaidou S, Perogamvrakis G, Papadakis CE: Accessory parotid gland carcinoma ex pleomorphic adenoma. Case study diagnosed by fine needle aspiration. Stomatologija; 2009;11(1):37-40

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Accessory parotid gland carcinoma ex pleomorphic adenoma. Case study diagnosed by fine needle aspiration.
  • OBJECTIVE: The accessory parotid gland is salivary tissue separated from the main parotid gland and lying on masseter muscle.
  • The accessory parotid gland exists in 21-61% of individuals.
  • However, the appearance of an accessory parotid tumor is rare, with a reported frequency of 1-7.7% of all parotid gland tumors.
  • Carcinoma ex pleomorphic adenoma arises from a pre-existing benign mixed tumor.
  • Most of these tumors will have malignant epithelial component, but not malignant stromal component.
  • Reports of Fine Needle Aspiration Cytological (FNAC) diagnosis of malignant mixed tumor are uncommon and have been limited to cases arising in the parotid.
  • We report a case of carcinoma ex pleomorphic adenoma of the accessory lobe of the parotid, and address the cytopathology features and pitfalls of this condition.
  • FNA was performed and the smears demonstrated features indicative of pleomorphic adenoma admixed with findings indicative of a poorly differentiated carcinoma.
  • CONCLUSION: FNAC can accurately diagnose carcinoma ex pleomorphic adenoma when strongly fixed requirements are implemented.

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  • (PMID = 19423970.001).
  • [ISSN] 1392-8589
  • [Journal-full-title] Stomatologija
  • [ISO-abbreviation] Stomatologija
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Lithuania
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62. van Heerden M, Everaert D, Vangeel L, Chiers K, van Loon G, Van Brantegem L, Ducatelle R: Tracheal carcinosarcoma (true malignant mixed tumour) in a Belgian Blue heifer. J Comp Pathol; 2005 Feb-Apr;132(2-3):237-41

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tracheal carcinosarcoma (true malignant mixed tumour) in a Belgian Blue heifer.
  • This report describes a case of a carcinosarcoma or true malignant mixed tumour (salivary gland type) of the trachea in a Belgian Blue heifer.
  • Histologically the tumour was biphasic, with varying proportions of epithelial elements dispersed throughout a matrix showing varying degrees of myxo-chondroid and cartilaginous differentiation.
  • The histological features of the tumour were consistent with a combination of an adenoid cystic carcinoma and a chondrosarcoma.
  • Immunolabelling demonstrated smooth muscle actin in the cytoplasm of both the epithelial and mesenchymal components, thus fulfilling the diagnostic criteria for a mixed tumour.
  • To our knowledge this is the first report of a mixed tumour of the trachea in a domestic animal.
  • [MeSH-minor] Actins / analysis. Animals. Biomarkers, Tumor / analysis. Cattle. Fatal Outcome. Female. Immunohistochemistry / methods. Immunohistochemistry / veterinary

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  • (PMID = 15737352.001).
  • [ISSN] 0021-9975
  • [Journal-full-title] Journal of comparative pathology
  • [ISO-abbreviation] J. Comp. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Actins; 0 / Biomarkers, Tumor
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63. Honda T, Yamamoto Y, Isago T, Nakazawa H, Nozaki M, Hirayama T: Giant pleomorphic adenoma of the parotid gland with malignant transformation. Ann Plast Surg; 2005 Nov;55(5):524-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant pleomorphic adenoma of the parotid gland with malignant transformation.
  • A 72-year-old female is described who was admitted to the hospital with a giant mixed tumor of the left parotid gland that had grown to a weight of 6051 g within 20 years and ultimately underwent resection of the mass.
  • Histopathological examination revealed adenocarcinoma cells with hyperchromatic nuclei and mitotic figures proliferated in pleomorphic adenoma.
  • Many authors have reported giant tumors weighing more than a few kilograms of the parotid glands, and most were benign.
  • The present tumor was the sixth largest among all the parotid tumors, including both benign and malignant, which were reported.
  • The tumor was successfully resected with no marked facial nerve paralysis.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Adenoma, Pleomorphic / surgery. Cell Transformation, Neoplastic / pathology. Parotid Neoplasms / pathology. Parotid Neoplasms / surgery

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  • (PMID = 16258307.001).
  • [ISSN] 0148-7043
  • [Journal-full-title] Annals of plastic surgery
  • [ISO-abbreviation] Ann Plast Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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64. Yao J, Chen RJ, Sun XH: [Analysis of the relationship between pathology and recurrence of primary lacrimal epithelial tumors]. Zhonghua Yan Ke Za Zhi; 2006 Jul;42(7):590-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Analysis of the relationship between pathology and recurrence of primary lacrimal epithelial tumors].
  • OBJECTIVE: To analyze the relationship between pathology and recurrence of primary lacrimal epithelial tumors.
  • METHODS: 128 cases of primary lacrimal epithelial tumors including benign mixed tumor (74 cases, 57.8%), adenoid cystic carcinoma (22 cases, 17.2%) and malignant mixed tumor (18 cases, 14.1%) were subjected in the study.
  • RESULTS: The recurrent rate of benign mixed tumor, adenoid cystic carcinoma and malignant mixed tumor was 23.0%, 18.2% and 27.8%, respectively.
  • The recurrence of benign mixed tumor was statistically related to pathological classification and encapsulates.
  • CONCLUSIONS: Primary lacrimal epithelial tumors show variant types and high recurrent rate.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Eye Neoplasms / pathology. Lacrimal Apparatus Diseases / pathology. Neoplasms, Complex and Mixed / pathology

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  • (PMID = 17081415.001).
  • [ISSN] 0412-4081
  • [Journal-full-title] [Zhonghua yan ke za zhi] Chinese journal of ophthalmology
  • [ISO-abbreviation] Zhonghua Yan Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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65. Schmidt LA, Olsen SH, McHugh JB: Cutaneous adnexal differentiation and stromal metaplasia in palate pleomorphic adenomas: a potential diagnostic pitfall that may be mistaken for malignancy. Am J Surg Pathol; 2010 Aug;34(8):1205-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous adnexal differentiation and stromal metaplasia in palate pleomorphic adenomas: a potential diagnostic pitfall that may be mistaken for malignancy.
  • Cutaneous adnexal differentiation is well-recognized in benign mixed tumors occurring in cutaneous sites.
  • The incidence of this histologic finding in salivary gland sites is not known.
  • We sought to describe the incidence of cutaneous adnexal differentiation in benign mixed tumors of the palate, lip, and parotid gland.
  • Benign mixed tumors of the palate (n=30), lip (n=13), and parotid gland (n=37) resected between 1980 and 2009 at a single academic medical institution were reviewed.
  • After confirming the diagnosis of benign mixed tumor, we evaluated for morphologic evidence of cutaneous adnexal differentiation and metaplastic epithelial and stromal changes.
  • Cutaneous adnexal differentiation was seen in 20% of palate and 39% of lip benign mixed tumors but in no parotid tumors.
  • The most frequent features of cutaneous adnexal differentiation were tricholemmal differentiation (20% of palate and 39% of lip tumors), infundibulocystic structures (17% and 31%), and trichohyalin granules (13% and 31%).
  • Sebaceous differentiation was seen in only one palate tumor.
  • Varying amounts of stromal adipose were seen in 62, 37, and 22% of lip, palate, and parotid tumors.
  • Osseous metaplasia was seen in one tumor from each site.
  • When cutaneous adnexal differentiation occurs in salivary gland pleomorphic adenomas, it can present a diagnostic pitfall that must not be misinterpreted as carcinoma at biopsy, fine needle aspiration, or frozen section.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Carcinoma / pathology. Cell Differentiation. Diagnostic Errors / prevention & control. Epithelial Cells / pathology. Mouth Neoplasms / pathology. Stromal Cells / pathology

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  • (PMID = 20661019.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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66. Kandasamy J, Smith A, Diaz S, Rose B, O'Brien C: Heterogeneity of PLAG1 gene rearrangements in pleomorphic adenoma. Cancer Genet Cytogenet; 2007 Aug;177(1):1-5
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  • [Title] Heterogeneity of PLAG1 gene rearrangements in pleomorphic adenoma.
  • Pleomorphic adenoma (PA), a benign mixed salivary gland tumor, has been associated with abnormal karyotypes in up to 70% of cases, with nonrandom involvement of 8q12, the locus of the pleomorphic adenoma (PLAG1) gene.
  • Samples of parotid gland tissue from the tumor sites, set up as solid tumor cultures, showed a normal karyotype in two cases [46,XY;46,XX] and cytogenetic abnormalities in five cases (71%).
  • In addition, genomic instability was seen in two cases, one with PLAG1 amplification in the form of a homogeneously staining region, and the other in der(8) ring formation.
  • [MeSH-major] Adenoma, Pleomorphic / genetics. DNA-Binding Proteins / genetics. Gene Rearrangement. Genetic Variation. Salivary Gland Neoplasms / genetics

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  • (PMID = 17693184.001).
  • [ISSN] 0165-4608
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA-Binding Proteins; 0 / PLAG1 protein, human
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67. Orzechowska-Wylegała B, Jedrzejewski P, Wylegała E, Steplewska K: Recurrent benign pleomorphic adenoma of the lacrimal gland--a case report. Klin Oczna; 2008;110(7-9):301-3

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  • [Title] Recurrent benign pleomorphic adenoma of the lacrimal gland--a case report.
  • Benign pleomorphic adenoma (mixed tumor) is the most frequently occurring tumor of epithelial origin.
  • It occurs in serous glands, most frequently in parotid glands and rarely in small palatine glands, cheek glands, palatine tonsils and the lacrimal gland.
  • This study is a description of the therapeutic management of a patient with recurrent pleomorphic adenoma of the lacrimal gland.
  • In 1996, a 35 year old male patient underwent surgery to remove a tumor of the left orbit.
  • Histopathological examination revealed pleomorphic adenoma.
  • In 2005, from a cut along the upper-outer edge of the left orbit, an elastic and soft tumor 1 cm in diameter was removed from soft tissues of the upper eyelid.
  • An eyelid nodule of 0.8 mm in diameter was removed together with an elastic and hard tumor of size 2.5 x 1 cm.
  • The result of the histopathological examination of the palpebral tumor was pseudocystic tumor and of the orbital tumor was pleomorphic adenoma.
  • CONCLUSION: patients resected for pleomorphic adenoma of the lacrimal gland require a long period of postoperative observation and periodic ophthalmologic examination.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Adenoma, Pleomorphic / surgery. Lacrimal Apparatus / pathology. Orbital Neoplasms / pathology. Orbital Neoplasms / surgery

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  • (PMID = 19112866.001).
  • [ISSN] 0023-2157
  • [Journal-full-title] Klinika oczna
  • [ISO-abbreviation] Klin Oczna
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
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68. Olajide TG, Alabi BS, Badmos BK, Bello OT: Pleomorphic adenoma of the lateral nasal wall--a case report. Niger Postgrad Med J; 2009 Sep;16(3):227-9
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  • [Title] Pleomorphic adenoma of the lateral nasal wall--a case report.
  • AIM/BACKGROUND: We report a rare case of pleomorphic adenoma arising from the lateral nasal wall.
  • The microscopic finding showed a lobular duct-like structure within a loose chondromyxoid stroma, which are histological characteristics of pleomorphic adenoma.
  • CONCLUSIONS: Her post-operative clinic visits were uneventful, and she is currently disease-free; nine months after surgery.
  • The diagnosis, clinical behaviour and treatment of pleomorphic adenoma of the lateral nasal wall are discussed from a review of the literature.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Nasal Cavity / radiography. Nose Neoplasms / pathology

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  • (PMID = 19767912.001).
  • [ISSN] 1117-1936
  • [Journal-full-title] The Nigerian postgraduate medical journal
  • [ISO-abbreviation] Niger Postgrad Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Nigeria
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69. do Prado RF, Consolaro A, Taveira LA: Expression of betacatenin in carcinoma in pleomorphic adenoma, pleomorphic adenoma and normal salivary gland: an immunohistochemical study. Med Oral Patol Oral Cir Bucal; 2006 May;11(3):E247-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of betacatenin in carcinoma in pleomorphic adenoma, pleomorphic adenoma and normal salivary gland: an immunohistochemical study.
  • OBJECTIVES: Pleomorphic adenomas are the most frequent type of epithelial salivary gland neoplasms, and their malignant counterpart, the carcinoma in pleomorphic adenomas, is much less common.
  • The objective of this study was to detect the expression of beta-catenin in pleomorphic adenomas, carcinomas in pleomorphic adenomas and normal salivary glands to discuss its role in the development of these two lesions.
  • STUDY DESIGN: The expression of beta-catenin (BD Transduction Laboratories) was analyzed by immunohistochemistry in formalin-fixed, paraffin embedded specimens by the avidin-biotin-peroxidase complex method in 16 pleomorphic adenomas (12 from minor salivary glands), 3 carcinomas in pleomorphic adenomas (all from palate) and 10 normal salivary glands as control group (5 from major and 5 from minor salivary glands).
  • RESULTS: All cases of glands, adenomas and carcinomas in pleomorphic adenomas have membranous and cytoplasmic immunostaining.
  • Higher beta-catenin index rates were seen mainly in salivary gland ducts and in ductal structures in the adenomas and carcinomas in pleomorphic adenomas.
  • There was protein loss in pleomorphic adenomas and cytoplasmic accumulation in carcinoma in pleomorphic adenomas.
  • CONCLUSIONS: The present study showed participation of the loss of beta-catenin adhesion molecule in the development of pleomorphic adenoma, and that the cytoplasmic accumulation of the molecule takes part in the malignant transformation of the pleomorphic adenoma into carcinoma in pleomorphic adenoma.
  • [MeSH-major] Adenoma, Pleomorphic / metabolism. Carcinoma / metabolism. Neoplasms, Multiple Primary / metabolism. Salivary Gland Neoplasms / metabolism. Salivary Glands / metabolism. beta Catenin / biosynthesis

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  • (PMID = 16648762.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / beta Catenin
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70. Trimeche Ajmi S, Chadli Chaieb M, Mokni M, Braham R, Ach K, Maaroufi A, Chaieb L: Corticomedullary mixed tumor of the adrenal gland. Ann Endocrinol (Paris); 2009 Dec;70(6):473-6
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  • [Title] Corticomedullary mixed tumor of the adrenal gland.
  • Abdominal magnetic resonance imaging showed a right heterogeneous adrenal mass measuring 4 x 6 cm with mixed component of fat and adrenal tissue suggesting corticosurrenaloma.
  • Histological examination showed a single tumor mass composed of an admixed population of adrenal cortical and medullary cells.
  • [MeSH-major] Adrenal Cortex / pathology. Adrenal Gland Neoplasms / diagnosis. Adrenal Medulla / pathology

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  • (PMID = 19878923.001).
  • [ISSN] 0003-4266
  • [Journal-full-title] Annales d'endocrinologie
  • [ISO-abbreviation] Ann. Endocrinol. (Paris)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Androgens; 0 / Chromogranin A; WI4X0X7BPJ / Hydrocortisone
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71. Ceylan A, Celenk F, Poyraz A, Uslu S: Pleomorphic adenoma of the nasal columella. Pathol Res Pract; 2008;204(4):273-6
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  • [Title] Pleomorphic adenoma of the nasal columella.
  • Pleomorphic adenoma (mixed tumor) is the most common benign neoplasm of the salivary glands.
  • It is considered to occur primarily in the major salivary glands, such as the parotid and submandibular glands.
  • It is much less common in the minor salivary glands, and rarely occurs at other sites, such as larynx, pharynx, trachea, lacrimal gland, and sinonasal tract.
  • We describe a very rare case of recurrent pleomorphic adenoma originating from the columella.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Neoplasm Recurrence, Local. Neoplasm Seeding. Nose Neoplasms / pathology

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  • (PMID = 18295980.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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72. Santos RR, Damasceno RW, de Pontes FS, Cursino SR, Nishiwaki-Dantas MC, Vital Filho J, Dantas PE: Ten-year follow-up of a case series of primary epithelial neoplasms of the lacrimal gland: clinical features, surgical treatment and histopathological findings. Arq Bras Oftalmol; 2010 Jan-Feb;73(1):33-9
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  • [Title] Ten-year follow-up of a case series of primary epithelial neoplasms of the lacrimal gland: clinical features, surgical treatment and histopathological findings.
  • PURPOSE: To describe and analyze the features of a cases series of patients with primary epithelial neoplasms of the lacrimal gland, its surgical treatment, and histopathological findings.
  • METHODS: Retrospective evaluation of files from patients with primary epithelial neoplasms of the lacrimal gland in the period from 1997 to 2007.
  • All patients with primary epithelial tumors of the lacrimal gland were included in this study.
  • The slides with histological sections of the tumors were reviewed by the same pathologist.
  • RESULTS: During the study period, there were 12 patients, 5 (41.7%) with benign tumors, all pleomorphic adenomas (benign mixed tumor) and 7 (58.3%) with malignant neoplasms, thus distributed: four cases of adenoid cystic carcinoma, two of mucoepidermoid carcinoma and one carcinoma expleomorphic adenoma.
  • Globally, patients mean age was 54.1 years-old (ranging from 14 to 70 years-old), with mean age of 52.4 years-old (ranging from 14 to 65 years-old) for benign neoplasms, and 55.3 years-old for malignant neoplasms (ranging from 26 to 70 years-old).
  • Three patients developed distant metastasis and died of disease.
  • CONCLUSIONS: The most frequent primary epithelial neoplasms of the lacrimal gland were pleomorphic adenoma and adenoid cystic carcinoma during the study period.
  • Malignant tumors were more frequent than benign tumors.
  • The histopathological diagnosis and the disease initial stage can play a significant role in patient's survival.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Carcinoma, Adenoid Cystic / pathology. Carcinoma, Mucoepidermoid / pathology. Lacrimal Apparatus / pathology. Lacrimal Apparatus Diseases / pathology

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  • (PMID = 20464111.001).
  • [ISSN] 1678-2925
  • [Journal-full-title] Arquivos brasileiros de oftalmologia
  • [ISO-abbreviation] Arq Bras Oftalmol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
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73. Gibson A, Mavrikakis I, Rootman J, Dolman P: Lacrimal gland pleomorphic adenomas with low-density zones resembling cystic change on computed tomography. Ophthal Plast Reconstr Surg; 2007 May-Jun;23(3):234-5
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  • [Title] Lacrimal gland pleomorphic adenomas with low-density zones resembling cystic change on computed tomography.
  • We report 2 cases of pleomorphic adenoma with unusual radiologic findings.
  • CT showed lacrimal gland masses dominated by low-density areas resembling cysts.
  • Pathology revealed the lesions to be pleomorphic adenomas with myxomatous and/or cartilaginous features.
  • [MeSH-major] Adenoma, Pleomorphic / radiography. Cysts / radiography. Eye Neoplasms / radiography. Lacrimal Apparatus Diseases / radiography. Tomography, X-Ray Computed

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  • (PMID = 17519667.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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74. Nickel J, Briese V, Briese J, Rehda E: Malignant melanoma and fibrothecoma--an ovarian mixed tumor. Anticancer Res; 2005 May-Jun;25(3A):1603-6
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  • [Title] Malignant melanoma and fibrothecoma--an ovarian mixed tumor.
  • Here, we report a rare case of ovarian mixed neoplasm with parts of malignant melanoma and fibrothecoma in a 76-year-old female who was hospitalized for a cataract operation.
  • To our knowledge, cases of a combination of malignant melanoma and fibrothecoma in the ovary have not been described.

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  • (PMID = 16033067.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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75. El Fakiri MM, Aderdour L, Nouri H, Hassani R, Maliki O, Raji A: [Pleomorphic adenoma of the nasal septum]. Rev Stomatol Chir Maxillofac; 2010 Jun;111(3):162-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pleomorphic adenoma of the nasal septum].
  • INTRODUCTION: The pleomorphic adenoma is the most common benign neoplasm of primary salivary glands.
  • We report a case of pleomorphic adenoma of the nasal septum.
  • A facial CT-scan showed a heterogeneous tumor of the nasal septum obstructing the left nasal vestibule.
  • The biopsy analysis proved the histological characteristics of a pleomorphic adenoma, and was further confirmed by immunohistochemical study.
  • DISCUSSION: The treatment of nasal pleomorphic adenomas must take into account lesion localization, esthetic complications, and evolutionary potential of the lesions.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Nasal Septum / pathology. Nose Neoplasms / diagnosis

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  • [Copyright] Copyright 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20416914.001).
  • [ISSN] 1776-257X
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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76. Helmstaedter V, Beutner D, Drebber U, Huttenbrink KB, Streppel M: [Multiple primary pleomorphic adenomas of the unilateral parotid gland]. Laryngorhinootologie; 2007 Jun;86(6):448-50

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  • [Title] [Multiple primary pleomorphic adenomas of the unilateral parotid gland].
  • [Transliterated title] Das unilaterale, primär multilokuläre pleomorphe Adenom der Ohrspeicheldrüse.
  • BACKGROUND: Classical lateral parotidectomy is the standard surgical procedure for the management of lateral lobe parotid pleomorphic adenomas in most clinical centres.
  • CASE: We report on a 20-year-old patient with multiple primary pleomorphic adenomas in the unilateral parotid gland, which preoperatively presented as a solitary tumour node.
  • CONCLUSION: Considering this case we focus on the distinctive surgical procedures for the management of parotid pleomorphic adenomas.
  • We work out, why lateral or even total parotidectomy are justified in the treatment of solitary palpable tumours and why we account lateral parotidectomy as the standard surgical procedure for the management of lateral lobe parotid pleomorphic adenomas.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Neoplasms, Multiple Primary / diagnosis. Parotid Neoplasms / diagnosis
  • [MeSH-minor] Adult. Dissection. Humans. Magnetic Resonance Imaging. Male. Parotid Gland / pathology. Parotid Gland / surgery

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  • (PMID = 17219338.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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77. Eladioui K, Ntima A, Noublanche P, Cucherousset N, Attar A: [Metastasis of a pleomorphic adenoma]. Rev Stomatol Chir Maxillofac; 2008 Jun;109(3):191-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Metastasis of a pleomorphic adenoma].
  • OBSERVATION: A 53-year-old man underwent a right parotidectomy in 1993 for a pleomorphic adenoma.
  • The tumor relapsed locally, three years later, imposing a reoperation.
  • Two years later, the excision of a new local recurrence revealed a histological evolution with intravascular emboli, some cellular atypia and some mitoses.
  • The patient died of a cerebral hemorrhage related to a history of familial autoimmune thrombocytopenia.
  • DISCUSSION: Regional and systemic metastases of pleomorphic adenomas are exceptional.
  • The local recurrence is characteristic of metastatic forms of pleomorphic adenomas; it occurs in 90% of the cases.
  • No clinical or histological criterion allows distinguishing between recurrent metastatic forms and non-recurrent metastatic pleomorphic adenomas.
  • The best treatment for metastases of a pleomorphic adenoma is surgical excision.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Parotid Neoplasms / pathology. Skull Neoplasms / secondary

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  • (PMID = 18533212.001).
  • [ISSN] 0035-1768
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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78. Parwani AV, Lujan G, Ali SZ: Myoepithelial carcinoma arising in a pleomorphic adenoma of the parotid gland: report of a case with cytopathologic findings. Acta Cytol; 2006 Jan-Feb;50(1):93-6
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  • [Title] Myoepithelial carcinoma arising in a pleomorphic adenoma of the parotid gland: report of a case with cytopathologic findings.
  • BACKGROUND: Carcinoma arising in a mixed tumor, or carcinoma ex pleomorphic adenoma (CEPA), is an uncommon primary salivary gland neoplasm.
  • Computed tomography-guide fine needle aspiration (FNA) showed a biphasic neoplasm with epithelial and stromal components consistent with pleomorphic adenoma (PA).
  • However, in addition, a distinct population of discohesive atypical and pleomorphic cells with high nuclear/cytoplasmic ratio was noted in the background.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Carcinoma / diagnosis. Myoepithelioma / diagnosis. Parotid Neoplasms / diagnosis

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  • (PMID = 16514848.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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79. Zhao X, Ren W, Yang W, Wang Y, Kong H, Wang L, Yan L, Xu G, Fei J, Fu J, Zhang C, Wang Z: Wnt pathway is involved in pleomorphic adenomas induced by overexpression of PLAG1 in transgenic mice. Int J Cancer; 2006 Feb 1;118(3):643-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Wnt pathway is involved in pleomorphic adenomas induced by overexpression of PLAG1 in transgenic mice.
  • Pleomorphic adenoma gene 1 (PLAG1) was found frequently rearranged and activated in human salivary gland pleomorphic adenomas.
  • Ectopic overexpression of PLAG1 has been proposed to play a crucial role in tumorigenesis of salivary gland pleomorphic adenomas.
  • In this report, we show that the salivary gland tumors developed in PLAG1 transgenic mice share major histopathologic features with human pleomorphic adenomas.
  • It was found that beta-catenin, the key component of Wnt signaling pathway, was upregulated at transcriptional level in tumors developed in 3 independent transgenic mouse lines.
  • Immunohistochemical staining revealed that expression of beta-catenin as well as c-myc, downstream of beta-catenin in Wnt signaling pathway, was highly upregulated with overexpression of PLAG1 transgene in tumor and normal transgenic salivary gland tissues.
  • Our findings provide the first in vivo evidence for the oncogenic activity of PLAG1 in pleomorphic adenoma tumorigenesis, reveal a valued animal model for human salivary gland tumors and suggest that Wnt signaling pathway may also contribute to the development of pleomorphic adenomas in transgenic mice.
  • [MeSH-major] Adenoma, Pleomorphic / genetics. DNA-Binding Proteins / physiology. Proto-Oncogene Proteins c-myc / metabolism. Salivary Gland Neoplasms / genetics. Signal Transduction. Wnt Proteins / metabolism. beta Catenin / metabolism

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  • [Copyright] Copyright 2005 Wiley-Liss, Inc.
  • (PMID = 16108035.001).
  • [ISSN] 0020-7136
  • [Journal-full-title] International journal of cancer
  • [ISO-abbreviation] Int. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA-Binding Proteins; 0 / Myc protein, mouse; 0 / PLAG1 protein, human; 0 / Proto-Oncogene Proteins c-myc; 0 / Wnt Proteins; 0 / beta Catenin
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80. Wong MH, Dobbins TA, Tseung J, Tran N, Lee CS, O'Brien CJ, Clark J, Rose BR: Oestrogen receptor beta expression in pleomorphic adenomas of the parotid gland. J Clin Pathol; 2009 Sep;62(9):789-93
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Oestrogen receptor beta expression in pleomorphic adenomas of the parotid gland.
  • AIMS: Pleomorphic adenomas of the salivary gland have gender and age distributions suggesting that oestrogen has a causal role.
  • However, oestrogen receptor (ER)alpha is expressed at low levels in normal salivary gland tissues and data from salivary gland tumours are conflicting.
  • There is preliminary evidence that the recently described ERbeta may be the major ER in salivary gland tissue.
  • The aim of this study was to determine the nature and extent of ERbeta expression in pleomorphic adenomas of the salivary gland.
  • METHODS: Pleomorphic adenomas and normal tissues of the parotid gland from 49 patients were tested for ERalpha and ERbeta expression by semiquantitative immunohistochemistry.
  • RESULTS: ERalpha and ERbeta expression was localised mainly to the nuclei of ductal cells in normal tissues and the epithelial components in pleomorphic adenomas.
  • Within each tissue and receptor type there were no associations between ER positivity and patient age or gender.
  • ERbeta was expressed in almost twice as many normal tissues and pleomorphic adenomas as ERalpha.
  • Expression of ERbeta was also significantly higher in tumour compared with normal tissues.
  • CONCLUSIONS: This is thought to be the first study of ERbeta in pleomorphic adenomas of the salivary gland.
  • Findings support ERbeta as the major ER in salivary glands, and provide evidence that ERbeta may have a role in the development of pleomorphic adenomas of the salivary gland.
  • [MeSH-major] Adenoma, Pleomorphic / metabolism. Estrogen Receptor beta / metabolism. Parotid Neoplasms / metabolism
  • [MeSH-minor] Adult. Age Factors. Estrogen Receptor alpha / metabolism. Female. Humans. Immunoenzyme Techniques. Male. Middle Aged. Neoplasm Proteins / metabolism. Parotid Gland / metabolism. Sex Factors

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  • (PMID = 19734474.001).
  • [ISSN] 1472-4146
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Estrogen Receptor alpha; 0 / Estrogen Receptor beta; 0 / Neoplasm Proteins
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81. Karakus MF, Ozcan KM, Dere H: Endoscopic resection of pleomorphic adenoma of the nasal septum. Tumori; 2007 May-Jun;93(3):300-1
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  • [Title] Endoscopic resection of pleomorphic adenoma of the nasal septum.
  • Pleomorphic adenomas originating from the minor salivary glands are rare in the nasal cavity.
  • Total surgical excision is the preferred treatment for pleomorphic adenomas.
  • Endoscopic tumor removal produces less morbidity, reduces blood loss during surgery, decreases hospital stay, avoids external scars and excessive unnecessary resection, enables the surgeon to better visualize the tumor margins, and has a low recurrence rate.
  • However, only 3 pleomorphic adenomas of the nasal septum have been removed by the endoscopic approach to date.
  • In this paper we report on a case of pleomorphic adenoma of the nasal septum that was removed successfully by the endoscopic approach without any recurrences.
  • [MeSH-major] Adenoma, Pleomorphic / surgery. Endoscopy. Nasal Septum / surgery. Nose Neoplasms / surgery

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  • (PMID = 17679469.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 11
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82. Chaari C, Ellouze S, Chamli H, Krichen Makni S, Karray F, Sellami Boudawara T: [Squamous cell carcinoma on a pleomorphic adenoma with amyloid stroma of the palate]. Rev Stomatol Chir Maxillofac; 2010 Feb;111(1):53-5
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  • [Title] [Squamous cell carcinoma on a pleomorphic adenoma with amyloid stroma of the palate].
  • INTRODUCTION: Squamous cell carcinoma ex-pleomorphic adenoma (CXAP) is a malignant and rare mixed tumor.
  • The physical examination revealed a hard and large tumor invading all the palate.
  • A histological study confirmed the diagnosis after surgical resection of the tumor, specifying its noninvasive character.
  • DISCUSSION: CXAP is generally located in the parotid gland; it is very rarely located in the palate.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Amyloid / analysis. Carcinoma, Squamous Cell / pathology. Neoplasms, Multiple Primary / pathology. Palatal Neoplasms / pathology

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  • (PMID = 19932498.001).
  • [ISSN] 1776-257X
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Amyloid; 68238-35-7 / Keratins; EC 3.4.24.11 / Neprilysin
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83. Dumitriu D, Dudea SM, Botar-Jid C, Băciuţ G: Ultrasonographic and sonoelastographic features of pleomorphic adenomas of the salivary glands. Med Ultrason; 2010 Sep;12(3):175-83
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  • [Title] Ultrasonographic and sonoelastographic features of pleomorphic adenomas of the salivary glands.
  • AIMS: The typical ultrasound features of pleomorphic adenomas are considered to be the well-defined contour, the regular, sometimes lobulated shape, homogeneous structure and poor vascularization.
  • The goal of our study was to verify the validity of these features and to identify a typical sonoelastographic pattern for pleomorphic adenomas.
  • PATIENTS AND METHODS: Between April 2007 and February 2010, 70 salivary gland masses were examined prospectively (58 in the parotid gland, 12 in the submandibular gland).
  • RESULTS: Of the 70 tumors, 32 (45.7%) were pleomorphic adenomas, 12 (17.1%) Warthin tumors, 9 (12.8%) other benign tumors, 13 (18.5%) primary malignant tumors, 3 metastases from carcinoma, and 1 non-Hodgkin lymphoma.
  • Among pleomorphic adenomas, 15 (46.9%) were inhomogeneous, 7 (21.9%) contained necrotic areas and 14 (43.7%) were well-vascularized.
  • The lobulated contour was identified in 14 pleomorphic adenomas (43.7%), no other benign tumor presented this type of contour, but it was identified in 2 malignant tumors (15.3%).
  • On sonoelastography, most pleomorphic adenomas were heterogeneous.
  • The elastic component represented more than 50% of the tumor tissue in 22 cases (68.7%).
  • This aspect was also identified for 6 malignant tumors (46.1%).
  • CONCLUSIONS: Our results demonstrate that features such as heterogeneous structure, rich vascularization and intra-tumoral necrosis may be identified in a significant number of pleomorphic adenomas.
  • The most specific element in our group was the presence of a lobulated contour, which was not seen in any other benign tumor, but may rarely appear in certain malignant tumors.
  • The elastographic aspect was heterogeneous for most tumors, but the elastic composition identified in most pleomorphic adenomas was also present in a significant proportion of malignant tumors.
  • Therefore, a typical sonoelastographic pattern for pleomorphic adenomas could not be identified.
  • [MeSH-major] Adenolymphoma / ultrasonography. Adenoma, Pleomorphic / ultrasonography. Elasticity Imaging Techniques / methods. Salivary Gland Neoplasms / ultrasonography

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  • (PMID = 21203593.001).
  • [ISSN] 1844-4172
  • [Journal-full-title] Medical ultrasonography
  • [ISO-abbreviation] Med Ultrason
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Romania
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84. Declercq J, Van Dyck F, Van Damme B, Van de Ven WJ: Upregulation of Igf and Wnt signalling associated genes in pleomorphic adenomas of the salivary glands in PLAG1 transgenic mice. Int J Oncol; 2008 May;32(5):1041-7
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  • [Title] Upregulation of Igf and Wnt signalling associated genes in pleomorphic adenomas of the salivary glands in PLAG1 transgenic mice.
  • The Pleomorphic adenoma gene 1 (PLAG1) is involved in various human neoplasias, including pleomorphic adenomas of the salivary glands.
  • MMTV-Cre-mediated targeted overexpression of PLAG1 in the salivary glands of double transgenic offspring mice, referred to as P1-MCre and P2-MCre mice, induced pleomorphic adenomas in this organ.
  • Igf2, a genuine PLAG1 target gene, was highly upregulated in those tumours as well as in human pleomorphic adenomas of the salivary glands.
  • Inactivation of Igf2 in P1-MCre mice leads to a significant delay in tumour development.
  • Since tumour development is not fully abrogated by inactivation of Igf2, other signalling pathways are likely to contribute to PLAG1-induced tumourigenesis as well.
  • In conclusion, we clearly demonstrate upregulation of several genes associated with Igf and Wnt signalling in PLAG1-induced pleomorphic adenomas.
  • [MeSH-major] Adenoma, Pleomorphic / metabolism. DNA-Binding Proteins / metabolism. Gene Expression Regulation, Neoplastic. Insulin-Like Growth Factor II / metabolism. Salivary Gland Neoplasms / metabolism. Signal Transduction / genetics. Wnt Proteins / metabolism

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  • (PMID = 18425330.001).
  • [ISSN] 1019-6439
  • [Journal-full-title] International journal of oncology
  • [ISO-abbreviation] Int. J. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / DNA-Binding Proteins; 0 / IGF2 protein, mouse; 0 / Plag1 protein, mouse; 0 / Wnt Proteins; 67763-97-7 / Insulin-Like Growth Factor II
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85. Nazarian Y, Talmi YP, Wolf M, Horowitz Z, Bedrin L, Pfeffer R, Kronenberg J: [Recurrent pleomorphic adenomas of the parotid gland--treatment and outcome]. Harefuah; 2007 Feb;146(2):82-4, 168
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  • [Title] [Recurrent pleomorphic adenomas of the parotid gland--treatment and outcome].
  • Epithelial tumors of the parotid gland comprise 3% of head and neck tumors, and 70%-80% of those are benign.
  • Pleomorphic adenoma is the most common tumor of the parotid gland.
  • Recurrence rate of pleomorphic adenomas (RPAs) following superficial parotidectomy was reported to be as high as 4%, sometimes associated with inadequate surgical treatment of the primary tumor.
  • These tumors have a very slow growth rate, and a ten-year follow-up period is mandatory.
  • Two patients (10%) had permanent paresis of a single branch of the facial nerve.
  • Seventeen out of 20 patients (85%) treated were disease-free after a follow-up period of 5 years.
  • [MeSH-major] Adenoma / pathology. Neoplasm Recurrence, Local / pathology. Parotid Neoplasms / pathology

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  • (PMID = 17352271.001).
  • [ISSN] 0017-7768
  • [Journal-full-title] Harefuah
  • [ISO-abbreviation] Harefuah
  • [Language] heb
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Israel
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86. Tarakji B, Nassani MZ: Survey of opinions on the management of pleomorphic adenoma among United Kingdom oral and maxillofacial surgeons. Kulak Burun Bogaz Ihtis Derg; 2010 May-Jun;20(3):129-36
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  • [Title] Survey of opinions on the management of pleomorphic adenoma among United Kingdom oral and maxillofacial surgeons.
  • OBJECTIVES: This study aims to highlight the current points of view regarding the management of pleomorphic adenomas among oral and maxillofacial surgeons in the United Kingdom.
  • The survey evaluated the surgical experience of the surgeon, the preferred surgical treatment of a newly diagnosed 3 cm diameter pleomorphic adenoma in the superficial lobe of the parotid gland in an adult and a child, and the treatment options of pleomorphic salivary adenoma (PSA) with the four following scenarios: (i) PSA with complete excision or incomplete excision;.
  • (ii) PSA with carcinoma in situ (atypical pleomorphic adenoma) with complete excision or incomplete excision;.
  • The results showed that there was no significant difference in the opinions of the respondents regarding treatment of pleomorphic adenoma in both adults and children.
  • There was a consensus on complete excision for the treatment of carcinoma in situ (atypical pleomorphic adenoma) or PSA with non-invasive malignant transformation.
  • CONCLUSION: This survey shows that superficial parotidectomy is the standard treatment method for primary pleomorphic adenoma in children and adults.
  • Surgery combined with radiotherapy is the preferred option in the case of multinodular recurrence, and surgery alone is recommended in the case of a solitary recurrence.
  • [MeSH-major] Adenoma, Pleomorphic / surgery. Health Care Surveys. Parotid Neoplasms / surgery
  • [MeSH-minor] Adult. Child. Combined Modality Therapy. Data Collection. Great Britain. Humans. Neoplasm Recurrence, Local / radiotherapy. Neoplasm Recurrence, Local / surgery. Otolaryngology. Salivary Gland Neoplasms / radiotherapy. Salivary Gland Neoplasms / surgery. Societies, Medical. Surgical Procedures, Operative / methods

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  • (PMID = 20465538.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Turkey
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87. Zheng YG, Zhao Y, Wu LY: [Metastasizing pleomorphic adenoma of the submandibular gland: a case report]. Hua Xi Kou Qiang Yi Xue Za Zhi; 2007 Jun;25(3):307-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Metastasizing pleomorphic adenoma of the submandibular gland: a case report].
  • Metastasizing pleomorphic adenomas without histological evidence of malignancy have rarely been reported.
  • A case of 30-year-old woman with a mass which showed a benign pleomorphic adenoma appearanced histologically in the left submandibular gland and right supercollarbone respectively was described.
  • Eight years ago, the patient suffered from pleomorphic adenoma of the left submandibular gland.
  • It revealed histopathologic features consistent with the recurrent and metastasizing tumor.
  • The clinic pathological features, possible mechanism and prevention approach of metastasizing pleomorphic adenoma were discussed based on previously reports in the literature.
  • [MeSH-major] Parotid Neoplasms. Submandibular Gland
  • [MeSH-minor] Adenoma, Pleomorphic. Female. Humans. Salivary Gland Neoplasms

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  • (PMID = 17629216.001).
  • [ISSN] 1000-1182
  • [Journal-full-title] Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology
  • [ISO-abbreviation] Hua Xi Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] Salivary Gland Adenoma, Pleomorphic
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88. Qureshi A, Barakzai A, Sahar NU, Gulzar R, Ahmad Z, Hassan SH: Spectrum of malignancy in mixed tumors of salivary gland: a morphological and immunohistochemical review of 23 cases. Indian J Pathol Microbiol; 2009 Apr-Jun;52(2):150-4
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  • [Title] Spectrum of malignancy in mixed tumors of salivary gland: a morphological and immunohistochemical review of 23 cases.
  • Malignancy arising in mixed tumors of the salivary gland is a distinct entity that can occur sporadically or in association with a background of pleomorphic adenoma.
  • Carcinoma arising with a background of pleomorphic adenoma is well documented.
  • However, there are rare occurrences of aggressive de novo carcinosarcomas of the parotid that have been reported.
  • We report 23 cases of tumors of the salivary gland comprising 18 cases of carcinoma ex pleomorphic adenoma, four cases of carcinosarcoma of the parotid and one case of benign metastasizing pleomorphic adenoma.
  • The occurrence of various malignancies suggests that this phenomenon is not very uncommon and should be looked for when reporting a mixed tumor.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Carcinoma / diagnosis. Carcinosarcoma / diagnosis. Mixed Tumor, Malignant / pathology. Mixed Tumor, Malignant / physiopathology. Salivary Gland Neoplasms / pathology. Salivary Gland Neoplasms / physiopathology

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  • (PMID = 19332899.001).
  • [ISSN] 0974-5130
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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89. Ascani G, Messi M, Balercia P: [Surgical management of pleomorphic adenoma of the salivary glands: our experience]. G Chir; 2008 Aug-Sep;29(8-9):343-6
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  • [Title] [Surgical management of pleomorphic adenoma of the salivary glands: our experience].
  • [Transliterated title] Trattamento dell'adenoma pleomorfo delle ghiandole salivari: nostra esperienza.
  • BACKGROUND: Pleomorphic adenoma is a benign epithelial tumour of adenoid structure preferentially arising from the parotid gland.
  • AIM: To analyse the outcome of patients with pleomorphic adenoma from salivary glands in order to evaluate the surgical strategy.
  • PATIENTS AND METHODS: This is an audit of a 15-year period where 347 pleomorphic adenomas of the salivary glands were treated by the authors.
  • RESULTS: The pleomorphic adenoma preferentially originated in the parotid gland (89.1%), and rarely in other glands.
  • The tumour occurred more often in females than in males (F:M=1.5).
  • CONCLUSION: The epidemiological aspects of pleomorphic adenoma of salivary glands retrieved in our study are similar to those reported in literature; moreover this study demonstrates that pericapsular enucleation is a viable alternative to superficial parotidectomy for the majority of parotid localizations, associated with reduced morbidity without oncological compromise.
  • [MeSH-major] Adenoma, Pleomorphic / surgery. Salivary Gland Neoplasms / surgery

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  • (PMID = 18834565.001).
  • [ISSN] 0391-9005
  • [Journal-full-title] Il Giornale di chirurgia
  • [ISO-abbreviation] G Chir
  • [Language] ita
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Italy
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90. Pelaz AC, Llorente Pendás JL, Bueno GC, Suárez Nieto C: Simultaneous pleomorphic adenomas of the hard palate and parapharyngeal space. J Craniofac Surg; 2009 Jul;20(4):1298-9
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  • [Title] Simultaneous pleomorphic adenomas of the hard palate and parapharyngeal space.
  • We report a very unusual presentation of simultaneous pleomorphic adenomas of 2 different locations, hard palate and parapharyngeal space.
  • Patient age of presentation is rare because these tumors are seen in younger patients.
  • We treated a 70-year-old woman with these 2 tumors, resecting both lesions with intraoral and cervical approaches.
  • Pleomorphic adenomas are frequent lesions, but in the literature reviewed, we have not found articles reporting 2 simultaneous pleomorphic adenomas of these locations.
  • [MeSH-major] Adenoma, Pleomorphic / surgery. Neoplasms, Multiple Primary / surgery. Palatal Neoplasms / surgery. Pharyngeal Neoplasms / surgery

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  • (PMID = 19625855.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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91. Gedlicka C, Item CB, Wögerbauer M, Martinek H, Heiduschka G, Erovic BM, Ch Grasl M, Thurnher D: Transformation of pleomorphic adenoma to carcinoma ex pleomorphic adenoma of the parotid gland is independent of p53 mutations. J Surg Oncol; 2010 Feb 1;101(2):127-30
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  • [Title] Transformation of pleomorphic adenoma to carcinoma ex pleomorphic adenoma of the parotid gland is independent of p53 mutations.
  • BACKGROUND AND OBJECTIVES: This retrospective study was performed to evaluate the status of p53 in pleomorphic adenomas and carcinomas ex pleomorphic adenoma in the parotid gland.
  • As loss or mutation of p53 can cause malignant transformation, the possible degeneration of pleomorphic adenomas to carcinomas ex pleomorhic adenoma was investigated by mutational analysis.
  • METHODS: Twenty-five Patients including 14 patients with pleomorphic adenomas and 11 patients with carcinoma ex pleomorphic adenoma of the parotid gland were examined for p53 status.
  • Denaturing gradient gel electrophoresis (DGGE) was carried out for mutational analysis and DNA sequencing was performed in case of a suspected mutation.
  • RESULTS: Fourteen pleomorphic adenomas and 11 carcinomas ex pleomorphic adenoma were screened for p53 status and potent mutations.
  • CONCLUSION: We could not detect mutations of p53 neither in benign nor malignant parotid tumors and we therefore assume that p53 plays no role in the transformation from pleomorphic adenoma to carcinoma ex pleomorphic adenoma.
  • [MeSH-major] Adenoma, Pleomorphic / genetics. Genes, p53 / genetics. Parotid Neoplasms / genetics

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  • (PMID = 19950209.001).
  • [ISSN] 1096-9098
  • [Journal-full-title] Journal of surgical oncology
  • [ISO-abbreviation] J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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92. Markou K, Karasmanis I, Vlachtsis K, Petridis D, Nikolaou A, Vital V: Primary pleomorphic adenoma of the external ear canal. Report of a case and literature review. Am J Otolaryngol; 2008 Mar-Apr;29(2):142-6
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  • [Title] Primary pleomorphic adenoma of the external ear canal. Report of a case and literature review.
  • INTRODUCTION: Primary neoplasms of the external ear canal are rare, and 5% of these tumors are of glandular origin.
  • Ceruminal glands are modified sweat glands of the skin of the external auditory meatus that may give rise to (a) benign tumors such as ceruminous adenoma, pleomorphic adenoma, and syringocystadenoma papilliferum, and (b) malignant tumors such as ceruminous adenocarcinoma, adenoid cystic carcinoma, and mucoepidermoid carcinoma.
  • An alternative theory holds that pleomorphic adenomas may well arise from ectopic salivary tissue present in the external ear canal.
  • These tumors are very rare and usually have a benign course.
  • In this report, we describe an unusual case of pleomorphic adenoma of the external auditory canal associated with chronic infection of the middle ear.
  • Subsequent biopsy and histologic examination revealed pleomorphic adenoma of the external ear canal, possibly with malignant elements.
  • Magnetic resonance imaging showed no intracranial extension or any association with the adjacent parotid gland.
  • The patient underwent modified radical mastoidectomy and complete resection of the tumor and the entire skin of the external auditory canal.
  • CONCLUSIONS: Pleomorphic adenoma is an extremely rare tumor arising from the ceruminal glands of the external ear canal.
  • Nonspecific presentation and difficult histologic diagnosis characterize this benign neoplasm.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Ear, External / pathology. Salivary Gland Neoplasms / pathology

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  • (PMID = 18314029.001).
  • [ISSN] 0196-0709
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 13
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93. Malinvaud D, Couloigner V, Badoual C, Halimi P, Bonfils P: Pleomorphic adenoma of the nasal septum and its relationship with Epstein-Barr virus. Auris Nasus Larynx; 2006 Dec;33(4):417-21
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  • [Title] Pleomorphic adenoma of the nasal septum and its relationship with Epstein-Barr virus.
  • OBJECTIVES: Pleomorphic adenoma is the most common benign tumor of the major salivary glands, especially of the parotid gland.
  • It is much less common in the minor salivary glands of the oral cavity, and it rarely occurs in others sites in the head and neck.
  • Even if virus involvement in salivary glands tumor has been many times discuted, the etiology of this tumor keeps being unknown.
  • As compared to other nasal tumors, we tried to prove if Epstein-Barr virus (EBV) could be involved in the development of pleomorphic adenoma in this particular nasal localization.
  • METHODS: Three cases of pleomorphic adenomas of the nasal septum (two women and a man in age of 23-59 years) were retrospectively studied.
  • All the patients had undergone endoscopic surgery to remove the complete tumor.
  • We used hybridation technique in the search for EBV-DNA in the three tumors.
  • RESULTS AND CONCLUSION: We had positive EBV-DNA detection in the tumor in one case, which seemed to prove relationship between pleomorphic adenoma and this virus.
  • The literature concerning the subject is reviewed in order to explain EBV involvement in the development of such tumors in this particular localization.
  • [MeSH-major] Adenoma, Pleomorphic / virology. DNA, Viral / analysis. Herpesvirus 4, Human / isolation & purification. Nasal Septum / surgery. Salivary Gland Neoplasms / virology

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  • (PMID = 16895748.001).
  • [ISSN] 0385-8146
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antibodies, Viral; 0 / DNA, Viral
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94. Stodulski D, Rzepko R, Kowalska B, Stankiewicz C: [Carcinoma ex pleomorphic adenoma of major salivary glands--a clinicopathologic review]. Otolaryngol Pol; 2007;61(5):687-93
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  • [Title] [Carcinoma ex pleomorphic adenoma of major salivary glands--a clinicopathologic review].
  • BACKGROUND: Pleomorphic adenoma (PA) is the most common neoplasm of the major salivary glands.
  • There are three subtypes of malignant PA: carcinoma ex pleomorphic adenoma (CXPA); carcinosarcoma (true malignant mixed tumor) and metastasizing pleomorphic adenoma.
  • For proper diagnosis of CXPA, a statement of coexistence of pleomorphic adenoma and carcinoma (or carcinoma after prior PA surgery) is needed.
  • The following clinical factors were evaluated: age, sex, symptoms (time of lasting, evolution), tumor size, invasion of the adjacent structures and facial nerve, neck nodes, clinical stage, treatment outcome.
  • One pathologist reviewed histological material of 18 out of 19 patients who had been operated and pathological factors such as sensitivity and accuracy of fine needle aspiration biopsy, grade, histology and proportion of malignant component in tumor, lymph nodes metastases were analyzed.
  • In 15 cases, tumor was localized in the parotid and in 4 in the submandibular gland.
  • Duration of symptoms of benign PA was from 2 to 40 years (mean 17.8 years).
  • Symptoms of malignant transformation occurred in 15 patients, the most common were rapid enlargement of tumor, pain and facial nerve palsy.
  • Tumor size varied from 2 to 20 cm with a mean of 6 cm.
  • 17 out of 18 tumors reviewed by the pathologist were high grade.
  • The best method of prevention and treatment of CXPA is early and radical removal of all major salivary glands tumors.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Carcinoma / pathology. Neoplasms, Multiple Primary / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands / pathology

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  • (PMID = 18552001.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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95. Rullo R, Festa VM, Accardo M, Ferraraccio F: The immunohistochemical outline of p27kip1, cyclin B1 and cyclin D3 in pleomorphic adenomas. Minerva Stomatol; 2006 Sep;55(9):483-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The immunohistochemical outline of p27kip1, cyclin B1 and cyclin D3 in pleomorphic adenomas.
  • AIM: Pleomorphic adenomas of salivary glands are benign lesions which may sometimes relapse even after complete surgical removal.
  • The authors intend to evaluate the degree of cellular aggression of these tumours by finding prognostic data using the antigens involved in cellular proliferative activity.
  • METHODS: Seventeen mixed tumours, 2 of them relapsed, underwent the direct immunohystochemical PAP technique for the determination of antigens p27kip1, cyclins B1 and D3 of the tissue.
  • CONCLUSIONS: On the basis of the results, the conclusion is drawn that there is no relation between the expressivity of the mentioned antigens and histological characters of pleomorphic adenomas.
  • [MeSH-major] Adenoma, Pleomorphic / chemistry. Biomarkers, Tumor / analysis. Cyclin B / analysis. Cyclin-Dependent Kinase Inhibitor p27 / analysis. Cyclins / analysis. Salivary Gland Neoplasms / chemistry

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  • (PMID = 17146427.001).
  • [ISSN] 0026-4970
  • [Journal-full-title] Minerva stomatologica
  • [ISO-abbreviation] Minerva Stomatol
  • [Language] eng; ita
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CCNB1 protein, human; 0 / CCND3 protein, human; 0 / Cyclin B; 0 / Cyclin B1; 0 / Cyclin D3; 0 / Cyclins; 147604-94-2 / Cyclin-Dependent Kinase Inhibitor p27
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96. Gao P, Zhou GY, Song XR, Hou JX, Zhang CJ, Ma C: [The relationship of abnormal expression of cell glucoprotein with recurrence of pleomorphic adenoma in salivary gland]. Hua Xi Kou Qiang Yi Xue Za Zhi; 2005 Apr;23(2):164-6
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  • [Title] [The relationship of abnormal expression of cell glucoprotein with recurrence of pleomorphic adenoma in salivary gland].
  • OBJECTIVE: To study the relationship of expression of mucin 1 and E-cadherin with recurrence of pleomorphic adenoma in salivary gland, and to investigate the signal to predict the recurrence potential of the tumor.
  • METHODS: ; The capsule of tumor was observed by microscope.
  • The expression of mucin 1 and E-cadherin in 33 cases of primary adenoma, 12 cases of recurrent pleomorphic adenomas and 7 cases of malignant pleomorphic adenomas were detected by immunohistochemistry.
  • RESULTS: There was no significant difference about the status of capsule and the positive rate of mucin 1 expression between primary and recurrent pleomorphic adenoma (P > 0.05).
  • The abnormal distribution of mucin 1 expression was observed in recurrent pleomorphic adenoma (6/8), which was characterized by the positive staining of the whole cytomembrane.
  • On the other hand, positive staining of the primary pleomorphic adenoma was observed on the top of the membrane (19/21).
  • The staining pattern in malignant pleomorphic adenoma was similar with the recurrent ones except higher ratio of positive expression.
  • No significant different was observed among the three kind of tumors on the expression rate of E-cadherin (P > 0.05).
  • CONCLUSION: The status of capsule didn't have much actual usage in predicting the recurrence of pleomorphic adenoma.
  • There was no significant relationship between the expression of E-cd and the recurrence of the tumor.
  • The abnormal distribution of mucin 1 expression contributes to the invasiveness of the tumor and can be used as the predictive signal for recurrence of pleomorphic adenoma.
  • [MeSH-major] Adenoma, Pleomorphic / physiopathology. Cadherins / metabolism. Mucin-1 / metabolism. Salivary Gland Neoplasms / physiopathology

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  • (PMID = 15952635.001).
  • [ISSN] 1000-1182
  • [Journal-full-title] Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology
  • [ISO-abbreviation] Hua Xi Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Cadherins; 0 / Mucin-1
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97. Brunese L, Ciccarelli R, Fucili S, Romeo A, Napolitano G, D'Auria V, Collina A, Califano L, Cappabianca S, Sodano A: Pleomorphic adenoma of parotid gland: delayed enhancement on computed tomography. Dentomaxillofac Radiol; 2008 Dec;37(8):464-9
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  • [Title] Pleomorphic adenoma of parotid gland: delayed enhancement on computed tomography.
  • OBJECTIVES: To assess the efficacy of multiphasic CT with 8 min delayed acquisition in the differential diagnosis between pleomorphic adenomas and other parotid neoplasias.
  • RESULTS: On histological examination, 36 tumours were classified as pleomorphic adenomas and 26 as non-pleomorphic adenomas.
  • On the basis of a statistical comparison, the third phase proved to be the most effective in the differential diagnosis between pleomorphic adenoma and non-pleomorphic adenomas, both for the assessment of the degree of the enhancement (in this phase, strong enhancement showed a sensitivity of 61.11%, specificity of 100%, positive predictive value (PPV) of 100% and negative predictive value (NPV) of 53.33%) and, above all, for the homogeneity of the enhancement (in this phase, indeed, uniform enhancement showed sensitivity, specificity, PPV and NPV of 100%).
  • CONCLUSIONS: Our results seem to indicate that multiphasic CT with 8 min delayed acquisition allows the differential diagnosis between pleomorphic adenomas and other parotid neoplasias.
  • [MeSH-major] Adenoma, Pleomorphic / radiography. Parotid Neoplasms / radiography. Radiographic Image Enhancement / methods. Tomography, X-Ray Computed / methods

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  • (PMID = 19033432.001).
  • [ISSN] 0250-832X
  • [Journal-full-title] Dento maxillo facial radiology
  • [ISO-abbreviation] Dentomaxillofac Radiol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Contrast Media
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98. Clarke LE, Seykora JT: Primary cutaneous adenomyoepithelioma. J Cutan Pathol; 2007 Aug;34(8):654-7
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  • An 83-year-old Caucasian woman presented to her dermatologist with a 5-cm subcutaneous tumor on her right thigh.
  • Incisional biopsy showed a multinodular tumor composed of variably sized glands comprised of a luminal layer of epithelial cells surrounded by one or more layers of myoepithelial cells.
  • Primary cutaneous adenomyoepithelioma is very rare yet shares histopathologic features with common cutaneous lesions such as spiradenomas and benign mixed tumors (chondroid syringomas).
  • Primary cutaneous adenomyoepithelioma is part of the spectrum of epithelial-myoepithelial tumors that includes benign mixed tumor, myoepithelioma and myoepithelial carcinoma.
  • This rare tumor may mimic malignant lesions including metastatic adenocarcinoma.

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  • (PMID = 17640238.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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99. Tarakji B, Nassani MZ: Immunohistochemical expression of p21 in normal tissues of salivary gland, pleomorphic adenoma and carcinoma ex pleomorphic adenoma-(undifferentiated and adenocarcinoma types). Med Oral Patol Oral Cir Bucal; 2010 Sep;15(5):e697-703
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Immunohistochemical expression of p21 in normal tissues of salivary gland, pleomorphic adenoma and carcinoma ex pleomorphic adenoma-(undifferentiated and adenocarcinoma types).
  • OBJECTIVE: Our study aimed to characterize alteration in the immunohistochemical expression of p21 in normal tissue of the salivary gland surrounding pleomorphic adenoma, the tumor cells of pleomorphic adenomas, and carcinoma arising in pleomorphic adenoma.
  • STUDY DESIGN: A selected series of 29 cases of pleomorphic adenomas, and 27 cases of carcinoma ex-pleomorphic adenoma (undifferentiated and adenocarcinoma types) were examined.
  • RESULTS: The results showed that p21 expression was negative in the most components of normal tissue of the salivary gland surrounding pleomorphic adenoma, 24 cases out of 29 of the non tumour duct cells (82.8%), and 28 (96.6%) cases out of 29 of the acinar cells shows negative p21 expression.
  • P21 expression in pleomorphic adenomas shows that 2 cases out of 29 (6.9%) strongly expressed in the duct cells. p21 was strongly expressed in carcinoma cells in 9 (33.3%) cases out of 27.
  • CONCLUSION: Our data suggest that the strong nuclear staining as an indicator for altered p21, then the alteration of p21 expression would increase from pleomorphic adenoma to carcinoma arising in pleomorphic adenomas (6.9% versus 33.3%).
  • [MeSH-major] Adenocarcinoma / metabolism. Adenoma, Pleomorphic / metabolism. Cyclin-Dependent Kinase Inhibitor p21 / biosynthesis. Salivary Gland Neoplasms / metabolism. Salivary Glands / metabolism

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  • (PMID = 20383106.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Cyclin-Dependent Kinase Inhibitor p21
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100. Lee BH: Unilateral agenesis of the parotid gland associated with a pleomorphic adenoma in the ipsilateral buccal space. Jpn J Radiol; 2010 Apr;28(3):224-6

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  • [Title] Unilateral agenesis of the parotid gland associated with a pleomorphic adenoma in the ipsilateral buccal space.
  • Unilateral agenesis of the parotid gland is a rare condition.
  • Although pleomorphic adenomas are the most common benign glandular tumors of the buccal space, to the author's knowledge unilateral agenesis of the parotid gland associated with pleomorphic adenoma in the ipsilatearal buccal space has not been previously described in the literature.
  • [MeSH-major] Adenoma, Pleomorphic / radiography. Cheek. Parotid Gland / abnormalities
  • [MeSH-minor] Aged. Female. Humans. Salivary Gland Neoplasms / radiography. Salivary Glands, Minor. Tomography, X-Ray Computed

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  • (PMID = 20437134.001).
  • [ISSN] 1867-108X
  • [Journal-full-title] Japanese journal of radiology
  • [ISO-abbreviation] Jpn J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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