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1. Takami HE, Ikeda Y: Minimally invasive thyroidectomy. Curr Opin Oncol; 2006 Jan;18(1):43-7
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  • Minimally invasive procedures have recently been adopted for the surgical treatment of thyroid disease as a means of preventing prominent scars, hypesthesia and paresthesia.
  • Our procedure differs from conventional thyroidectomy in requiring a 3-cm skin incision, and in not raising of a skin flap and not dissecting the sternohyoid muscle.
  • SUMMARY: Endoscopic thyroidectomy is the procedure of choice in well selected patients with thyroid disease.
  • The present indications for this procedure include benign follicular adenomas less than 4 cm in diameter, low-risk papillary carcinomas less than 10 mm, oxyphilic cell tumors less than 4 cm and Graves' disease as imaged on preoperative ultrasonography.
  • Total thyroidectomy and bilateral modified neck dissection is possible, if the tumor is not large.

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  • (PMID = 16357563.001).
  • [ISSN] 1040-8746
  • [Journal-full-title] Current opinion in oncology
  • [ISO-abbreviation] Curr Opin Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 3K9958V90M / Ethanol
  • [Number-of-references] 17
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2. Picken MM, Chyna B, Flanigan RC, Lee JM: Analysis of chromosome 1p abnormalities in renal oncocytomas by loss of heterozygosity studies: correlation with conventional cytogenetics and fluorescence in situ hybridization. Am J Clin Pathol; 2008 Mar;129(3):377-82
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  • We previously showed by cytogenetics and fluorescence in situ hybridization (FISH) that the most common chromosomal abnormality in renal oncocytomas is loss of chromosome 1 or 1p.
  • [MeSH-major] Adenoma, Oxyphilic / genetics. Chromosomes, Human, Pair 1 / genetics. Kidney Neoplasms / genetics
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Chromosome Aberrations. DNA, Neoplasm / analysis. Female. Humans. In Situ Hybridization, Fluorescence. Loss of Heterozygosity. Male. Microsatellite Repeats. Middle Aged. Polymerase Chain Reaction

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  • (PMID = 18285259.001).
  • [ISSN] 0002-9173
  • [Journal-full-title] American journal of clinical pathology
  • [ISO-abbreviation] Am. J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm
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3. Alshumrani G, O'Malley M, Ghai S, Metser U, Kachura J, Finelli A, Mattar K, Panzarella T: Small (< or = 4 cm) cortical renal tumors: characterization with multidetector CT. Abdom Imaging; 2010 Aug;35(4):488-93
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  • Two radiologists reviewed CT studies blinded to pathology results and recorded the morphologic and enhancement features of the tumors.
  • [MeSH-minor] Adenoma, Oxyphilic / pathology. Adenoma, Oxyphilic / radiography. Adult. Aged. Aged, 80 and over. Angiomyolipoma / pathology. Angiomyolipoma / radiography. Carcinoma, Renal Cell / pathology. Carcinoma, Renal Cell / radiography. Female. Granuloma, Plasma Cell / pathology. Granuloma, Plasma Cell / radiography. Humans. Kidney Diseases / pathology. Kidney Diseases / radiography. Male. Middle Aged

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  • (PMID = 19536589.001).
  • [ISSN] 1432-0509
  • [Journal-full-title] Abdominal imaging
  • [ISO-abbreviation] Abdom Imaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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4. Roy C Sr, El Ghali S, Buy X, Lindner V, Lang H, Saussine C, Jacqmin D: Significance of the pseudocapsule on MRI of renal neoplasms and its potential application for local staging: a retrospective study. AJR Am J Roentgenol; 2005 Jan;184(1):113-20
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  • MR images exhibited a pseudocapsule in 90% of cases as a hypointense rim surrounding the tumor on T2-weighted images.
  • It is more likely to predict that the tumor can be removed by partial surgery.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Carcinoma, Renal Cell / pathology. Kidney Neoplasms / pathology. Magnetic Resonance Imaging. Neoplasm Staging / methods

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  • (PMID = 15615960.001).
  • [ISSN] 0361-803X
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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5. Landry CS, Grubbs EG, Perrier ND: Bilateral robotic-assisted transaxillary surgery. Arch Surg; 2010 Aug;145(8):717-20
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  • RESULTS: Right thyroid lobectomy was performed via RATS to remove a 2.2-cm Hurthle cell neoplasm of the thyroid gland per cytologic analysis.
  • [MeSH-major] Adenoma, Oxyphilic / surgery. Robotics. Thyroid Neoplasms / surgery. Thyroidectomy / methods

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  • (PMID = 20713921.001).
  • [ISSN] 1538-3644
  • [Journal-full-title] Archives of surgery (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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6. Hes O, Michal M, Kuroda N, Martignoni G, Brunelli M, Lu Y, Adley BP, Alvarado-Cabrero I, Yang XJ: Vimentin reactivity in renal oncocytoma: immunohistochemical study of 234 cases. Arch Pathol Lab Med; 2007 Dec;131(12):1782-8
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  • CONTEXT: The expression of vimentin in benign renal oncocytomas has been controversial.
  • RESULTS: We found that the focal vimentin immunoreactivity can be seen in most (72.6%) renal oncocytomas with vimentin-positive tumor cells usually found in the edge of a central scar or in small clusters scattered throughout the tumor.
  • Because the vimentin staining patterns in renal oncocytomas are different from those seen in clear cell or papillary renal cell carcinomas, we consider vimentin staining to be helpful in the differential diagnosis of oncocytoma from other renal tumor mimics.
  • Furthermore, strong vimentin positivity in a renal cell neoplasm does not exclude the diagnosis of renal oncocytoma, particularly in a limited biopsy specimen.
  • [MeSH-major] Adenoma, Oxyphilic / metabolism. Kidney Neoplasms / metabolism. Vimentin / biosynthesis

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  • (PMID = 18081436.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Vimentin
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7. Tamaskar I, Choueiri TK, Sercia L, Rini B, Bukowski R, Zhou M: Differential expression of caveolin-1 in renal neoplasms. Cancer; 2007 Aug 15;110(4):776-82
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  • Both membranous and cytoplasmic caveolin-1 expression levels were measured and were correlated with tumor size, Fuhrman nuclear grade, and pathologic stage.
  • Only membranous caveolin-1 expression was correlated with tumor size (Pearson correlation = 0.266; P = .043).
  • There was no correlation between membranous or cytoplasmic caveolin-1 expression and other pathologic parameters, including Fuhrman nuclear grade and staging according to the American Joint Committee on Cancer tumor, lymph node, metastasis classification system.
  • [MeSH-minor] Adenocarcinoma, Clear Cell / metabolism. Adenocarcinoma, Clear Cell / pathology. Adenoma, Oxyphilic / metabolism. Adenoma, Oxyphilic / pathology. Adult. Aged. Aged, 80 and over. Carcinoma, Papillary / metabolism. Carcinoma, Papillary / pathology. Carcinoma, Renal Cell / metabolism. Carcinoma, Renal Cell / pathology. Cohort Studies. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Kidney / chemistry. Kidney / pathology. Male. Middle Aged. Tissue Array Analysis

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  • (PMID = 17594718.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Caveolin 1
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8. Saqi A, Giorgadze TA, Eleazar J, Remotti F, Vazquez MF: Clear cell and eosinophilic oncocytomas of salivary gland: cytological variants or parallels? Diagn Cytopathol; 2007 Mar;35(3):158-63
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  • [Title] Clear cell and eosinophilic oncocytomas of salivary gland: cytological variants or parallels?
  • Oncocytomas are uncommon tumors of the salivary gland.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Eosinophils / pathology. Salivary Gland Neoplasms / pathology

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  • (PMID = 17415919.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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9. Müller-Höcker J, Babaryka G, Schmid I, Jung A: Overexpression of cyclin D1, D3, and p21 in an infantile renal carcinoma with Xp11.2 TFE3-gene fusion. Pathol Res Pract; 2008;204(8):589-97
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  • 2 translocations/TFE3-gene fusion represent a special type of renal neoplasm showing deregulation of specific cell cycle components.
  • [MeSH-major] Adenoma, Oxyphilic. Basic Helix-Loop-Helix Leucine Zipper Transcription Factors / genetics. Carcinoma, Renal Cell. Cell Cycle Proteins / analysis. Chromosomes, Human, X. Gene Fusion. Kidney Neoplasms. Neoplasm Proteins / genetics

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  • (PMID = 18358634.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; 0 / CCND3 protein, human; 0 / CDKN1A protein, human; 0 / Cell Cycle Proteins; 0 / Cyclin D; 0 / Cyclin D3; 0 / Cyclin-Dependent Kinase Inhibitor p21; 0 / Cyclins; 0 / Neoplasm Proteins; 0 / PRCC protein, human; 0 / TFE3 protein, human
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10. Kim JY, Park HY, Paik JS, Kim DC, Yang SW: Oncocytoma of the lacrimal gland: an Asian case. Jpn J Ophthalmol; 2010 May;54(3):239-41
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  • [Title] Oncocytoma of the lacrimal gland: an Asian case.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Eye Neoplasms / pathology. Lacrimal Apparatus / pathology

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  • [Cites] Klin Monbl Augenheilkd. 1983 Jun;182(6):544-8 [6876649.001]
  • [Cites] Orbit. 2006 Sep;25(3):243-7 [16987774.001]
  • [Cites] Diagn Cytopathol. 2009 Jun;37(6):443-5 [19217061.001]
  • [Cites] Arch Ophthalmol. 1977 Mar;95(3):474-8 [843279.001]
  • [Cites] Acta Ophthalmol Scand. 2007 Aug;85(5):576-7 [17590206.001]
  • (PMID = 20577859.001).
  • [ISSN] 1613-2246
  • [Journal-full-title] Japanese journal of ophthalmology
  • [ISO-abbreviation] Jpn. J. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Japan
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11. Bisceglia M, Fisher C, Suster S, Kazakov DV, Cooper K, Michal M: Tumoral, quasitumoral and pseudotumoral lesions of the superficial and somatic soft tissue: new entities and new variants of old entities recorded during the last 25 years. Part IX: excerpta VII. Pathologica; 2005 Oct;97(5):343-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adenoma, Oxyphilic / chemistry. Adenoma, Oxyphilic / diagnosis. Adenoma, Oxyphilic / pathology. Adenoma, Pleomorphic / chemistry. Adenoma, Pleomorphic / diagnosis. Adenoma, Pleomorphic / pathology. Adult. Aged. Biomarkers, Tumor / analysis. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Myoepithelioma / chemistry. Myoepithelioma / classification. Myoepithelioma / diagnosis. Myoepithelioma / pathology. Neoplasms, Germ Cell and Embryonal / chemistry. Neoplasms, Germ Cell and Embryonal / diagnosis. Neoplasms, Germ Cell and Embryonal / pathology. Retrospective Studies. Skin Neoplasms / chemistry. Skin Neoplasms / diagnosis. Skin Neoplasms / pathology

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  • (PMID = 16480035.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 117
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12. Yamashita R, Nakamura M, Matsuzaki M, Matsui T, Yamaguchi R, Niwakawa M, Tobisu K, Asakura K, Ito I: [Clinical factors associated with benign renal tumors]. Nihon Hinyokika Gakkai Zasshi; 2009 Nov;100(7):679-85
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  • [Title] [Clinical factors associated with benign renal tumors].
  • OBJECTIVES: In this study, we sought to define the incidence of benign renal tumors in our institute and to clarify the clinical factors associated with benign renal tumors, in order to assist in forming preoperative differential diagnoses.
  • We also compared clinical factors, including age, sex and tumor size, between the benign and malignant renal tumors.
  • RESULTS: The patient's median age was 67 years (mean age, 63 years), and the median tumor diameter was 3.0 cm (mean, 3.2 cm).
  • Benign renal tumors were found in 10 (12%) of the 81 tumors; these included seven cases of oncocytoma and three cases of angiomyolipoma with minimal fat.
  • Several factors were significant clinical determinants of differentiation between benign and malignant renal tumors: homogeneity in CT, female gender, and small tumor size all predominated in cases of benign tumors.
  • CONCLUSIONS: When a patient, especially a female, presents with a small and homogeneous renal tumor, careful consideration should be given to the possibility of a benign process, which needs further consideration before performing excessive surgery.
  • [MeSH-major] Adenoma, Oxyphilic. Angiomyolipoma. Kidney Neoplasms

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  • (PMID = 19999132.001).
  • [ISSN] 0021-5287
  • [Journal-full-title] Nihon Hinyōkika Gakkai zasshi. The japanese journal of urology
  • [ISO-abbreviation] Nippon Hinyokika Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Japan
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13. Monchik JM, DeLellis RA: Re-operative neck surgery for well-differentiated thyroid cancer of follicular origin. J Surg Oncol; 2006 Dec 15;94(8):714-8
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  • This review focuses on the pathologic criteria for completion thyroidectomy in well differentiated thyroid cancer as well the diagnosis and treatment of recurrent disease.
  • The roles of ultrasound in the diagnosis of a cervical recurrence, its value in determining the extent of lymph node dissection in the lateral compartment, and the importance of intra-operative ultrasound in re-operative thyroid surgery are discussed.
  • [MeSH-major] Neck Dissection. Neoplasm Recurrence, Local / surgery. Thyroid Neoplasms / pathology. Thyroid Neoplasms / surgery. Thyroidectomy
  • [MeSH-minor] Adenocarcinoma, Follicular / surgery. Adenoma, Oxyphilic / surgery. Carcinoma, Papillary / surgery. Catheter Ablation. Humans. Neoplasm, Residual. Reoperation


14. Antic T, Venkataraman G, Oshima K: Oncocytic epithelial-myoepithelial carcinoma: an evolving new variant with comparative immunohistochemistry. Pathology; 2008 Jun;40(4):415-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Biomarkers, Tumor / analysis. Myoepithelioma / pathology. Parotid Neoplasms / pathology


15. Rocca PC, Brunelli M, Gobbo S, Eccher A, Bragantini E, Mina MM, Ficarra V, Zattoni F, Zamò A, Pea M, Scarpa A, Chilosi M, Menestrina F, Bonetti F, Eble JN, Martignoni G: Diagnostic utility of S100A1 expression in renal cell neoplasms: an immunohistochemical and quantitative RT-PCR study. Mod Pathol; 2007 Jul;20(7):722-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adenoma, Oxyphilic / diagnosis. Adenoma, Oxyphilic / genetics. Adenoma, Oxyphilic / metabolism. Diagnosis, Differential. Humans. Immunohistochemistry. Kidney / chemistry. Kidney / metabolism. Kidney / pathology. RNA, Messenger / genetics. RNA, Messenger / metabolism. Reverse Transcriptase Polymerase Chain Reaction. Sensitivity and Specificity

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  • (PMID = 17483815.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / RNA, Messenger; 0 / S100 Proteins; 0 / S100A1 protein
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16. Camargo RS, Maeda MY, di Loreto C, Shirata NK, Anselmo Garcia E, Filho AL: Is agNOR and DNA ploidy analysis useful for evaluating thyroid neoplasms? Anal Quant Cytol Histol; 2005 Jun;27(3):157-61
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  • DNA analysis correlated with histologic type of the tumor (p = 0.032).

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  • (PMID = 16121637.001).
  • [ISSN] 0884-6812
  • [Journal-full-title] Analytical and quantitative cytology and histology
  • [ISO-abbreviation] Anal. Quant. Cytol. Histol.
  • [Language] ENG
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Nuclear; 0 / Nuclear Proteins; 0 / nucleolar organizer region associated proteins
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17. Borota OC, Scheithauer BW, Fougner SL, Hald JK, Ramm-Pettersen J, Bollerslev J: Spindle cell oncocytoma of the adenohypophysis: report of a case with marked cellular atypia and recurrence despite adjuvant treatment. Clin Neuropathol; 2009 Mar-Apr;28(2):91-5
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  • [Title] Spindle cell oncocytoma of the adenohypophysis: report of a case with marked cellular atypia and recurrence despite adjuvant treatment.
  • Spindle cell oncocytoma (SCO) of the adenohypophysis is a recently defined pituitary tumor mimicking a non-functioning macroadenoma and composed of mitochondrion rich tumor cells, positive for S-100, vimentin, epithelial membrane antigen and galectin-3 but lacking cytokeratins, pituitary hormones, and neuroendocrine markers.
  • 10 cases of SCO have been reported to date; of these, 8 underwent a benign clinical course and 2 recurred.
  • Despite the benign course of most reported cases, additional experience with longer follow-up are needed to assess clinical, histopathologic, and proliferative indices and their relevance to optimal therapy for this rare pituitary tumor.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Pituitary Gland, Anterior. Pituitary Neoplasms / pathology
  • [MeSH-minor] Female. Galectin 3 / analysis. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Middle Aged. Mucin-1 / analysis. Neoplasm Recurrence, Local. Radiotherapy, Adjuvant. S100 Proteins / analysis. Treatment Outcome

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  • (PMID = 19353839.001).
  • [ISSN] 0722-5091
  • [Journal-full-title] Clinical neuropathology
  • [ISO-abbreviation] Clin. Neuropathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Galectin 3; 0 / Mucin-1; 0 / S100 Proteins
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18. Brunelli M, Gobbo S, Cossu-Rocca P, Cheng L, Ficarra V, Novara G, Menestrina F, Chilosi M, Martignoni G: Fluorescent cytogenetics of renal cell neoplasms. Pathologica; 2008 Dec;100(6):454-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adenocarcinoma, Mucinous / diagnosis. Adenocarcinoma, Mucinous / genetics. Adenocarcinoma, Mucinous / pathology. Adenoma / diagnosis. Adenoma / genetics. Adenoma / pathology. Adenoma, Oxyphilic / diagnosis. Adenoma, Oxyphilic / genetics. Adenoma, Oxyphilic / pathology. Adult. Aneuploidy. Carcinoma, Papillary / diagnosis. Carcinoma, Papillary / genetics. Carcinoma, Papillary / pathology. Child. Chromosome Aberrations. Chromosomes, Human / ultrastructure. Chromosomes, Human, X / ultrastructure. Humans. Kidney Failure, Chronic / complications. Translocation, Genetic

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  • (PMID = 19475886.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 54
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19. Eldahshan S, Celia A, Zeccolini G, Guerini A, Breda G: Laparoscopic transperitoneal adrenalectomy for adrenocortical oncocytoma. Arch Ital Urol Androl; 2008 Jun;80(2):82-4
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  • [Title] Laparoscopic transperitoneal adrenalectomy for adrenocortical oncocytoma.
  • A middle aged male patient (39 year old) presented with right renal pain.
  • During evaluation a small renal stone was found in the right kidney, and a mass 6 cm in diameter related to the upper pole of the left kidney was discovered.
  • An endocrinologic evaluation was negative and a laparoscopic transperitoneal adrenalectomy was performed.
  • Final pathology was adrenocortical oncocytoma with malignant potential.

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  • (PMID = 18683814.001).
  • [ISSN] 1124-3562
  • [Journal-full-title] Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica
  • [ISO-abbreviation] Arch Ital Urol Androl
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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20. Park BK: Comments on "Distribution of renal tumor growth rates determined by using serial volumetric CT measurements". Radiology; 2009 Jul;252(1):314; author reply 314-5
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  • [Title] Comments on "Distribution of renal tumor growth rates determined by using serial volumetric CT measurements".
  • [MeSH-minor] Adenoma, Oxyphilic / pathology. Adenoma, Oxyphilic / radiography. Adenoma, Oxyphilic / surgery. Adult. Aged. Aged, 80 and over. Angiomyolipoma / pathology. Angiomyolipoma / radiography. Angiomyolipoma / surgery. Carcinoma, Papillary / pathology. Carcinoma, Papillary / radiography. Carcinoma, Papillary / surgery. Carcinoma, Renal Cell / pathology. Carcinoma, Renal Cell / radiography. Carcinoma, Renal Cell / surgery. Disease Progression. Female. Humans. Male. Mathematical Computing. Middle Aged. Neoplasm Staging

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  • [CommentOn] Radiology. 2009 Jan;250(1):137-44 [19092093.001]
  • (PMID = 19561267.001).
  • [ISSN] 1527-1315
  • [Journal-full-title] Radiology
  • [ISO-abbreviation] Radiology
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] United States
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21. Brennan C, Srigley JR, Whelan C, Cooper J, Delahunt B: Type 2 and clear cell papillary renal cell carcinoma, and tubulocystic carcinoma: a unifying concept. Anticancer Res; 2010 Feb;30(2):641-4
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  • The clinical and pathological features of multiple different renal neoplasms arising in a setting of end-stage renal disease in a 72-year-old male are described.
  • The occurrence of these three tumours in a setting of end-stage kidney disease is unique and suggests a common pathogenesis.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Carcinoma, Papillary / pathology. Carcinoma, Renal Cell / pathology. Kidney Neoplasms / pathology. Kidney Tubules / pathology. Neoplasms, Multiple Primary / pathology


22. Sakuma T, Nishimura K, Deturmeny J, Kawano K: [Functioning oxyphil cell adenoma of parathyroid diagnosed with ureteral stone]. Prog Urol; 2009 Oct;19(9):636-8
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  • [Title] [Functioning oxyphil cell adenoma of parathyroid diagnosed with ureteral stone].
  • A case of oxyphil cell adenoma of parathyroid is presented.
  • Left hydronephrosis, elevated serum calcium-parathyroid hormone and a nodule in the right neck suggested functioning parathyroid adenoma.
  • Resected adenoma (15 mm x 10 mm x 5 mm) was exclusively composed of oxyphil cell.
  • This case was found to be the smallest parathyroid oxyphil cell adenoma hitherto reported that caused urolithiasis.
  • [MeSH-major] Adenoma, Oxyphilic / complications. Adenoma, Oxyphilic / diagnosis. Parathyroid Neoplasms / complications. Parathyroid Neoplasms / diagnosis. Ureteral Calculi / complications

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  • (PMID = 19800555.001).
  • [ISSN] 1166-7087
  • [Journal-full-title] Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie
  • [ISO-abbreviation] Prog. Urol.
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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23. Pobes Martínez De Salinas A, Suárez Laurés AM, Quiñones Ortiz L, Menéndez Fernández CL: [Renal oncocytoma and papillary microcarcinoma coexisting with cystic disease acquired before dialysis]. Nefrologia; 2008;28(3):356-7
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  • [Title] [Renal oncocytoma and papillary microcarcinoma coexisting with cystic disease acquired before dialysis].
  • [MeSH-major] Adenoma, Oxyphilic / complications. Carcinoma, Papillary / complications. Kidney Diseases, Cystic / complications. Kidney Neoplasms / complications. Neoplasms, Multiple Primary / complications

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  • (PMID = 18590511.001).
  • [ISSN] 0211-6995
  • [Journal-full-title] Nefrología : publicación oficial de la Sociedad Española Nefrologia
  • [ISO-abbreviation] Nefrologia
  • [Language] spa
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Spain
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24. Pezzolla A, Lattarulo S, Milella M, Barile G, Pascazio B, Ciampolillo A, Fabiano G, Palasciano N: [Incidental carcinoma in thyroid pathology: our experience and review of the literature]. Ann Ital Chir; 2010 May-Jun;81(3):165-9
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  • The diagnosis of incidental thyroid carcinoma in patients submitted to thyroidectomy for a benign disease is quite frequent.
  • One hundred sixty five patients (68.75%) were affected by benign disease (132 multinodular goiter, 30 uninodular goiter, 2 Plummer and 1 Basedow) and 75 (31.25%) by carcinoma.
  • In 30 of 165 patients (18.2 %), affected by benign disease, occurred a histological diagnosis of thyroid carcinoma, (18 papillary carcinoma, 6 follicular carcinoma, 5 papillary carcinoma follicular variant and 1 oncocytic carcinoma).
  • Actually these patients are still in a follow up program and no recurrency of disease is occasionally observed.
  • This study shows that the only way to put doubts on the real benignity of the disease is the fine needle aspiration; there are no other instruments that could let think about the occurrence of the carcinoma.
  • [MeSH-minor] Adenoma, Oxyphilic / pathology. Adolescent. Adult. Aged. Aged, 80 and over. Biopsy, Fine-Needle. Diagnosis, Differential. Female. Goiter, Nodular / pathology. Graves Disease / pathology. Humans. Incidence. Italy / epidemiology. Male. Middle Aged. Plummer-Vinson Syndrome / pathology. Predictive Value of Tests. Retrospective Studies. Sensitivity and Specificity

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  • (PMID = 21105480.001).
  • [ISSN] 0003-469X
  • [Journal-full-title] Annali italiani di chirurgia
  • [ISO-abbreviation] Ann Ital Chir
  • [Language] ita
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Italy
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25. Bałdys-Waligórska A, Gołkowski F, Krzentowska-Korek A, Hubalewska-Dydejczyk A: Radioiodine ablation of thyroid remnants in patients with differentiated thyroid carcinoma (DTC) following administration of rhTSH - a comparison with L-thyroxine withdrawal. Endokrynol Pol; 2010 Sep-Oct;61(5):474-9
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  • [MeSH-minor] Adenocarcinoma, Follicular. Adenoma, Oxyphilic. Female. Humans. Lymph Node Excision. Male. Middle Aged. Neoplasm Staging. Neoplasm, Residual. Postoperative Care. Thyroid Neoplasms / pathology. Thyroid Neoplasms / radiotherapy. Thyroid Neoplasms / surgery. Thyroidectomy. Thyroxine / administration & dosage

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  • (PMID = 21049461.001).
  • [ISSN] 0423-104X
  • [Journal-full-title] Endokrynologia Polska
  • [ISO-abbreviation] Endokrynol Pol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Iodine Radioisotopes; 9002-71-5 / Thyrotropin; Q51BO43MG4 / Thyroxine; Thyroid cancer, Hurthle cell
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26. Walsh CA, Quinlan DM: Oncocytoma and synchronous urothelial carcinoma in same kidney: previously unreported association. Urology; 2005 Jul;66(1):194
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  • We report the first case of a benign oncocytoma and a urothelial carcinoma occurring synchronously in the same kidney in a man who underwent radical nephrectomy for a suspicious renal mass.
  • [MeSH-major] Adenoma, Oxyphilic / surgery. Carcinoma, Transitional Cell / surgery. Kidney Neoplasms / surgery. Neoplasms, Multiple Primary / surgery

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  • (PMID = 15921729.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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27. Park HS, Jang KY, Kang MJ, Song KJ, Lee KB: Oncocytoma of the spinal cord causing paraplegia - a case report. Spinal Cord; 2007 Feb;45(2):183-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenoma, Oxyphilic / complications. Paraplegia / etiology. Spinal Cord Neoplasms / complications
  • [MeSH-minor] Adult. Antigens, Neoplasm. Female. Humans. Immunohistochemistry / methods. Melanoma-Specific Antigens. Neoplasm Proteins / metabolism

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  • (PMID = 16505829.001).
  • [ISSN] 1362-4393
  • [Journal-full-title] Spinal cord
  • [ISO-abbreviation] Spinal Cord
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
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28. Akiyama T, Sadahira Y, Irei I, Nishimura H, Hida AI, Notohara K, Hamazaki S: Pancreatic serous microcystic adenoma with extensive oncocytic change. Pathol Int; 2009 Feb;59(2):102-6
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  • [Title] Pancreatic serous microcystic adenoma with extensive oncocytic change.
  • Herein is reported a case of pancreatic serous microcystic adenoma with extensive oncocytic change in a 73-year-old woman.
  • Histologically the tumor consisted of numerous small cysts, separated by thin or broad fibrous septa.
  • Immunohistochemically, the cyst-lining cells were positive for cytokeratin (CK) 7, CK19, MUC1, MUC6, alpha-inhibin, and neuron-specific enolase (NSE), and negative for CK8, CK20, MUC2, and MUC5AC; these immunoprofiles coincide with those of serous microcystic adenoma.
  • Thus, this case is considered a variant of serous microcystic adenoma characterized by extensive oncocytic change.
  • [MeSH-major] Adenoma / pathology. Adenoma, Oxyphilic / pathology. Oxyphil Cells / pathology. Pancreatic Neoplasms / pathology
  • [MeSH-minor] Aged. Autoantibodies / analysis. Biomarkers, Tumor / analysis. Cytoplasm / chemistry. Female. Humans. Mitochondria / immunology. Pancreaticoduodenectomy. Treatment Outcome


29. Etit D, Tan A, Bayol U, Altinel D, Cumurcu S, Cukurova I: Oncocytic carcinoma ex pleomorphic adenoma. Head Neck Pathol; 2010 Mar;4(1):49-52
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  • [Title] Oncocytic carcinoma ex pleomorphic adenoma.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Adenoma, Pleomorphic / pathology. Neoplasms, Multiple Primary / pathology. Parotid Gland / pathology. Parotid Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Combined Modality Therapy. Disease-Free Survival. Humans. Immunohistochemistry. Male. Middle Aged

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  • [Cites] Hum Pathol. 2001 Jun;32(6):596-604 [11431714.001]
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  • (PMID = 20237989.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ PMC2825533
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30. Flanagan JN, Pineda P, Knapp PE, De Las Morenas A, Lee SL, Braverman LE: Expression of cytokeratin 19 in the diagnosis of thyroid papillary carcinoma by quantitative polymerase chain reaction. Endocr Pract; 2008 Mar;14(2):168-74
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  • Tissue sections were stained for CK19 expression with use of a specific monoclonal antibody. qPCR was performed on synthesized complementary DNA with sequence-specific primers for human CK19 in conjunction with ribonucleoprotein S18 for normalization.
  • HT and Hürthle cell adenoma were essentially negative for CK19 immunostaining, except for weak staining in focal areas.
  • Hürthle cell adenoma (n = 5) and HT (n = 7) lesions were similar to MNG in CK19 expression, with some overlap of CK19 between HT and PC.
  • [MeSH-minor] Adenoma, Oxyphilic / diagnosis. Adenoma, Oxyphilic / genetics. Adenoma, Oxyphilic / metabolism. Diagnosis, Differential. Gene Expression Regulation, Neoplastic. Goiter, Nodular / diagnosis. Goiter, Nodular / genetics. Goiter, Nodular / metabolism. Hashimoto Disease / diagnosis. Hashimoto Disease / genetics. Hashimoto Disease / metabolism. Humans. Immunohistochemistry

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  • (PMID = 18308654.001).
  • [ISSN] 1934-2403
  • [Journal-full-title] Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
  • [ISO-abbreviation] Endocr Pract
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Keratin-19
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31. Milas M, Barbosa GF, Mitchell J, Berber E, Siperstein A, Gupta M: Effectiveness of peripheral thyrotropin receptor mRNA in follow-up of differentiated thyroid cancer. Ann Surg Oncol; 2009 Feb;16(2):473-80
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  • TSHR mRNA levels were correlated to thyroglobulin (Tg), imaging studies, and disease status during follow-up.
  • Advanced-stage disease occurred in 24% at presentation, and 11 (32%) developed cervical node metastases or recurrence requiring reoperation during follow-up.
  • TSHR mRNA missed disease in 21% patients, but was better than Tg in 27%, including all those with Tg antibodies.
  • TSHR mRNA concurred with whole-body scan detectable disease for 11/14 patients (79%) and accurately predicted overall TC disease status in 77% patients.
  • [MeSH-minor] Adenocarcinoma, Follicular / blood. Adenocarcinoma, Follicular / secondary. Adenocarcinoma, Follicular / surgery. Adenoma, Oxyphilic / blood. Adenoma, Oxyphilic / secondary. Adenoma, Oxyphilic / surgery. Adult. Aged. Autoantibodies / blood. Biomarkers, Tumor / blood. Carcinoma, Papillary / blood. Carcinoma, Papillary / secondary. Carcinoma, Papillary / surgery. Cell Differentiation. Female. Follow-Up Studies. Humans. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Recurrence, Local / blood. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / surgery. Positron-Emission Tomography. Prospective Studies. Reverse Transcriptase Polymerase Chain Reaction. Thyroglobulin / blood. Thyroglobulin / genetics. Thyroglobulin / immunology. Thyroidectomy. Thyrotropin / pharmacology. Young Adult

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  • (PMID = 19015922.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Autoantibodies; 0 / Biomarkers, Tumor; 0 / RNA, Messenger; 0 / Receptors, Thyrotropin; 9002-71-5 / Thyrotropin; 9010-34-8 / Thyroglobulin
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32. Buckley O, Feeney J, Geoghegan T, Torreggiani WC: Oncocytoma in a horseshoe kidney. Br J Hosp Med (Lond); 2006 Oct;67(10):547
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenoma, Oxyphilic / diagnosis. Kidney / abnormalities. Kidney Neoplasms / diagnosis

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  • (PMID = 17069135.001).
  • [ISSN] 1750-8460
  • [Journal-full-title] British journal of hospital medicine (London, England : 2005)
  • [ISO-abbreviation] Br J Hosp Med (Lond)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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33. Saillant J, Fontana L, Biat I, Boudet G, Maublant C, Chamoux A: Report of three cases of renal oncocytoma in the same French chemical industrial factory. J Occup Environ Med; 2009 Oct;51(10):1113-5
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  • [Title] Report of three cases of renal oncocytoma in the same French chemical industrial factory.

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  • (PMID = 19820548.001).
  • [ISSN] 1536-5948
  • [Journal-full-title] Journal of occupational and environmental medicine
  • [ISO-abbreviation] J. Occup. Environ. Med.
  • [Language] ENG
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
  • [Chemical-registry-number] WD06X94M2D / Vinyl Chloride
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34. Jayaratna I, Munver R, Disick G, Han MW, Sawczuk I: Paraneoplastic hypertension associated with renal oncocytoma: management with cryoablation. Urology; 2009 Jan;73(1):209.e9-11
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  • We report a unique case of a patient with multidrug-resistant hypertension who was found to have a solitary renal mass.
  • To our knowledge, this is the first report of hypertension in the setting of a renal oncocytoma, with subsequent improvement of this paraneoplastic syndrome after cryoablation.
  • [MeSH-major] Adenoma, Oxyphilic / complications. Adenoma, Oxyphilic / surgery. Cryosurgery. Hypertension / etiology. Hypertension / surgery. Kidney Neoplasms / complications. Kidney Neoplasms / surgery. Paraneoplastic Syndromes / etiology. Paraneoplastic Syndromes / surgery


35. Hruby GW, Fine JK, Landman J: Ultrasound-guided percutaneous ablation of a renal mass in a renal allograft. Urology; 2006 Oct;68(4):891.e5-6
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  • [Title] Ultrasound-guided percutaneous ablation of a renal mass in a renal allograft.
  • The final histopathologic examination of the needle biopsy was consistent with an oncocytic neoplasm.
  • The 9-month follow-up contrast-enhanced magnetic resonance imaging scan showed no residual tumor.
  • [MeSH-major] Adenoma, Oxyphilic / surgery. Cryosurgery / methods. Kidney Neoplasms / surgery. Kidney Transplantation / pathology. Transplantation, Homologous / pathology


36. Widziszowska A, Namysłowski G, Hajduk A, Lange D: [Parapharyngeal oncocytoma of the parotid gland--case report]. Otolaryngol Pol; 2007;61(2):195-7
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  • [Title] [Parapharyngeal oncocytoma of the parotid gland--case report].
  • Oncocytoma is a rare, benign salivary gland tumour with slowly course.
  • It usually occurs in the parotid gland, seldom in submandibular gland.
  • This report presents a case of parapharyngeal oncocytoma of the left parotid gland in 77-year-old patient, treated in 2nd ENT Department of Medical University of Silesia in Zabrze.
  • The removal of a whole tumour was performed through a cervical--transpharyngeal approach with midline mandibulotomy.
  • [MeSH-major] Adenoma, Oxyphilic / diagnosis. Adenoma, Oxyphilic / surgery. Parotid Neoplasms / diagnosis. Parotid Neoplasms / surgery
  • [MeSH-minor] Aged. Female. Humans. Magnetic Resonance Imaging. Parotid Gland / radiography. Parotid Gland / surgery. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 17668810.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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37. Blankenship DR, Chin E, Terris DJ: Contemporary management of thyroid cancer. Am J Otolaryngol; 2005 Jul-Aug;26(4):249-60
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  • Thyroid cancer is a relatively common and frequently curable malignant neoplasm, accounting for nearly 2% of all new cancers diagnosed annually in the United States.
  • In addition to reviewing well-established approaches to diagnosis and management, emphasis is placed on newer techniques, including minimally invasive thyroidectomy, molecular detection of disease propensity, and the use of recombinant thyrotropin prior to radioiodine ablation.
  • [MeSH-minor] Adenocarcinoma, Follicular / diagnosis. Adenocarcinoma, Follicular / pathology. Adenocarcinoma, Follicular / therapy. Adenocarcinoma, Papillary / diagnosis. Adenocarcinoma, Papillary / pathology. Adenocarcinoma, Papillary / therapy. Adenoma, Oxyphilic / diagnosis. Adenoma, Oxyphilic / pathology. Adenoma, Oxyphilic / therapy. Biopsy, Fine-Needle. Carcinoma / diagnosis. Carcinoma / pathology. Carcinoma / therapy. Carcinoma, Medullary / diagnosis. Carcinoma, Medullary / pathology. Carcinoma, Medullary / therapy. Evidence-Based Medicine. Humans. Lymphoma / diagnosis. Lymphoma / pathology. Lymphoma / therapy. Thyroid Gland / anatomy & histology. Thyroid Gland / embryology. Thyroid Gland / radionuclide imaging. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 15991091.001).
  • [ISSN] 0196-0709
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 90
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38. Rowsell C, Fleshner N, Marrano P, Squire J, Evans A: Papillary renal cell carcinoma within a renal oncocytoma: case report of an incidental finding of a tumour within a tumour. J Clin Pathol; 2007 Apr;60(4):426-8
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  • [Title] Papillary renal cell carcinoma within a renal oncocytoma: case report of an incidental finding of a tumour within a tumour.
  • The most common renal tumours are clear cell, papillary, chromophobe and collecting duct renal cell carcinomas (RCCs), and benign oncocytomas and angiomyolipomas.
  • The incidental finding of a papillary RCC located in an oncocytoma in a nephrectomy specimen from a 75-year-old man is described.
  • To our knowledge, this is the first report of a papillary RCC being identified within an oncocytoma.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Carcinoma, Renal Cell / pathology. Kidney Neoplasms / pathology. Mixed Tumor, Malignant / pathology


39. Caplan RH: Radioactive iodine scanning and treatment in management of Hürthle cell thyroid carcinoma. Endocr Pract; 2006 May-Jun;12(3):342; author reply 342
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenoma, Oxyphilic / radionuclide imaging. Adenoma, Oxyphilic / therapy. Iodine Radioisotopes / therapeutic use. Thyroid Neoplasms / radionuclide imaging. Thyroid Neoplasms / therapy

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  • [CommentOn] Endocr Pract. 2005 Jul-Aug;11(4):285-9 [16006295.001]
  • (PMID = 16772210.001).
  • [ISSN] 1530-891X
  • [Journal-full-title] Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
  • [ISO-abbreviation] Endocr Pract
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Iodine Radioisotopes
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40. Allory Y: [Practical approach to a kidney tumor with papillary architecture in the adult]. Ann Pathol; 2009 Nov;29 Spec No 1:S55-8
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  • [Title] [Practical approach to a kidney tumor with papillary architecture in the adult].
  • [MeSH-major] Adenoma / pathology. Adenoma, Oxyphilic / pathology. Carcinoma, Renal Cell / pathology. Kidney Neoplasms / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Carcinoma / secondary. Carcinoma, Transitional Cell / chemistry. Carcinoma, Transitional Cell / pathology. Chromosomes, Human, X / genetics. Chromosomes, Human, X / ultrastructure. Humans. Neoplasm Proteins / analysis. Translocation, Genetic

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  • (PMID = 19887252.001).
  • [ISSN] 0242-6498
  • [Journal-full-title] Annales de pathologie
  • [ISO-abbreviation] Ann Pathol
  • [Language] fre
  • [Publication-type] Journal Article; Review
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
  • [Number-of-references] 9
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41. Gobbo S, Eble JN, Delahunt B, Grignon DJ, Samaratunga H, Martignoni G, Zhang S, Wang M, Brunelli M, Cossu-Rocca P, Cheng L: Renal cell neoplasms of oncocytosis have distinct morphologic, immunohistochemical, and cytogenetic profiles. Am J Surg Pathol; 2010 May;34(5):620-6
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  • [Title] Renal cell neoplasms of oncocytosis have distinct morphologic, immunohistochemical, and cytogenetic profiles.
  • In summary, the renal cell neoplasms of oncocytosis seem to have distinct morphologic, immunohistochemical, and cytogenetic profiles and likely are a distinct entity, not closely related to oncocytoma or chromophobe renal cell carcinoma.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Carcinoma, Renal Cell / pathology. Kidney Neoplasms / pathology. Neoplasms, Multiple Primary / pathology
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Centromere / genetics. Chromosome Deletion. Female. Humans. Immunohistochemistry. In Situ Hybridization, Fluorescence. Keratin-7 / analysis. Male. Middle Aged. Parvalbumins / analysis. S100 Proteins / analysis. X Chromosome Inactivation / genetics

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  • (PMID = 20305535.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Keratin-7; 0 / Parvalbumins; 0 / S100 Proteins; 0 / S100A1 protein
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42. DeWitt J, Gress FG, Levy MJ, Hernandez LV, Eloubeidi MA, Mishra G, Sherman S, Al-Haddad MA, LeBlanc JK: EUS-guided FNA aspiration of kidney masses: a multicenter U.S. experience. Gastrointest Endosc; 2009 Sep;70(3):573-8
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  • To date, only 3 known cases of EUS-guided FNA (EUS-FNA) of a renal mass have been reported.
  • OBJECTIVE: To describe a multicenter experience with the indications, yield, and complications from attempted EUS-FNA of a kidney mass.
  • PATIENTS: Consecutive subjects undergoing attempted EUS-FNA of a kidney mass.
  • INTERVENTIONS: EUS-FNA of a kidney mass.
  • Results of EUS-FNA (median 3 passes; range 2-4 passes) in 13 (87%) procedures were diagnostic of (n = 7) or highly suspicious for (n = 1) renal cell carcinoma (RCC), atypical cells (n = 2), oncocytoma (n = 1), benign cyst (n = 1), and nondiagnostic (n = 1).
  • [MeSH-minor] Adenoma, Oxyphilic / pathology. Adenoma, Oxyphilic / ultrasonography. Aged. Aged, 80 and over. Carcinoma, Renal Cell / pathology. Carcinoma, Renal Cell / ultrasonography. Cohort Studies. Confidence Intervals. Female. Follow-Up Studies. Hospitals, Teaching. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Staging. Probability. Retrospective Studies. Risk Assessment. Sensitivity and Specificity. United States

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  • (PMID = 19560139.001).
  • [ISSN] 1097-6779
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
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43. Kauffman EC, Barocas DA, Chen YT, Yang XJ, Scherr DS, Tu JJ: Differential expression of KAI1 metastasis suppressor protein in renal cell tumor histological subtypes. J Urol; 2009 May;181(5):2305-11
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  • [Title] Differential expression of KAI1 metastasis suppressor protein in renal cell tumor histological subtypes.
  • PURPOSE: The similar appearance of renal tumor histological subtypes can complicate differential diagnoses.
  • This problem is most notable for the chromophobe subtype of renal cell carcinoma, which can be histologically indistinguishable from oncocytoma with investigational molecular markers failing to provide reliable differentiation.
  • KAI1 is a metastasis suppressor gene whose expression correlates inversely with the metastatic potential of most solid tumor cancer types.
  • We tested the hypothesis that KAI1 is differentially expressed among renal tumor histological subtypes.
  • MATERIALS AND METHODS: Immunohistochemical staining for KAI1 protein was performed in 152 nephrectomy specimens, including 48 clear cell, 35 papillary and 31 chromophobe renal cell carcinoma samples, 28 oncocytomas and 10 tumor-free kidneys.
  • RESULTS: In all 10 tumor-free kidneys KAI1 protein was detected exclusively in distal tubule cell membranes.
  • Of the tumor specimens KAI1 protein was absent in all papillary renal cell carcinoma specimens.
  • [MeSH-major] Adenoma, Oxyphilic / genetics. Carcinoma, Renal Cell / genetics. Carcinoma, Renal Cell / pathology. Extracellular Matrix Proteins / metabolism. Kidney Neoplasms / genetics. Kidney Neoplasms / pathology. Nerve Tissue Proteins / metabolism
  • [MeSH-minor] Biomarkers, Tumor / genetics. Biopsy, Needle. Case-Control Studies. Diagnosis, Differential. Female. Gene Expression Regulation, Neoplastic. Humans. Immunohistochemistry. Male. Nephrectomy. Prognosis. Reference Values. Risk Assessment. Sampling Studies. Sensitivity and Specificity

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  • (PMID = 19303095.001).
  • [ISSN] 1527-3792
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Extracellular Matrix Proteins; 0 / KAL1 protein, human; 0 / Nerve Tissue Proteins
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44. Bonora E, Porcelli AM, Gasparre G, Biondi A, Ghelli A, Carelli V, Baracca A, Tallini G, Martinuzzi A, Lenaz G, Rugolo M, Romeo G: Defective oxidative phosphorylation in thyroid oncocytic carcinoma is associated with pathogenic mitochondrial DNA mutations affecting complexes I and III. Cancer Res; 2006 Jun 15;66(12):6087-96
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  • [MeSH-major] Adenoma, Oxyphilic / genetics. Adenoma, Oxyphilic / metabolism. DNA, Mitochondrial / genetics. Electron Transport Complex I / genetics. Electron Transport Complex III / genetics. Thyroid Neoplasms / genetics. Thyroid Neoplasms / metabolism
  • [MeSH-minor] Adenosine Triphosphate / metabolism. Bone Neoplasms / enzymology. Bone Neoplasms / genetics. Bone Neoplasms / metabolism. Bone Neoplasms / pathology. Cell Line, Tumor. Cell Survival / physiology. Humans. Osteosarcoma / enzymology. Osteosarcoma / genetics. Osteosarcoma / metabolism. Osteosarcoma / pathology. Oxidative Phosphorylation. Reactive Oxygen Species / metabolism


45. Lallu S, Naran S, Bethwaite P: Fine needle aspiration cytology of unsuspected metastatic hurthle cell carcinoma of the thyroid and its pitfalls: a report of two cases. Diagn Cytopathol; 2007 Jul;35(7):439-43
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  • These cases are of interest as the bland cytologic features may lead to an erroneous benign diagnosis.
  • Immunohistochemistry aids the definitive diagnosis of metastatic Hurthle cell carcinoma of thyroid especially when the presence of a previous thyroid lesion is not communicated to the laboratory.
  • [MeSH-major] Adenoma, Oxyphilic / secondary. Biopsy, Fine-Needle. Bone Neoplasms / secondary. Skin Neoplasms / secondary. Thyroid Neoplasms / pathology

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  • (PMID = 17580356.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Historical Article; Journal Article
  • [Publication-country] United States
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46. Picken MM: Editorial comment from Dr Picken to Molecular pathology of renal oncocytoma: a review. Int J Urol; 2010 Jul;17(7):613-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenoma, Oxyphilic. Kidney Neoplasms

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  • [CommentOn] Int J Urol. 2010 Jul;17(7):602-12 [20590944.001]
  • (PMID = 20590946.001).
  • [ISSN] 1442-2042
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] Australia
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47. Petrolla AA, MacLennan GT: Renal cell carcinoma and other concurrent renal neoplasms. J Urol; 2007 Nov;178(5):2163
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Angiomyolipoma / pathology. Carcinoma, Renal Cell / pathology. Kidney Neoplasms / pathology. Neoplasms, Multiple Primary / pathology

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  • (PMID = 17870118.001).
  • [ISSN] 0022-5347
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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48. Yuen HK, Cheuk W, Cheng AC, Anh C, Chan N: Malignant oncocytoma of the lacrimal sac as an unusual cause of epiphora. Ophthal Plast Reconstr Surg; 2007 Jan-Feb;23(1):70-2
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  • CT revealed an extensive inferomedial orbital tumor connected to the lacrimal sac and duct.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Eye Neoplasms / pathology. Lacrimal Apparatus Diseases / pathology
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Combined Modality Therapy. Humans. Immunoenzyme Techniques. Male. Ophthalmologic Surgical Procedures. Tomography, X-Ray Computed

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  • (PMID = 17237701.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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49. Zhuang Z, Huang S, Kowalak JA, Shi Y, Lei J, Furuta M, Lee YS, Lubensky IA, Rodgers GP, Cornelius AS, Weil RJ, Teh BT, Vortmeyer AO: From tissue phenotype to proteotype: sensitive protein identification in microdissected tumor tissue. Int J Oncol; 2006 Jan;28(1):103-10
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  • [Title] From tissue phenotype to proteotype: sensitive protein identification in microdissected tumor tissue.
  • Correlation of disease phenotype with protein profile (proteotype) is a significant challenge for biomedical research.
  • We obtained reliable and highly consistent results in phenotypically similar tumors of each individual subtype by performing strict morphological control of the analyzed tumor cells without physical or chemical alteration of the frozen tissue samples.
  • This new combination of techniques allows not only for sensitive identification of specific protein patterns that correspond to a histological tumor phenotype, but also for identification of specific disease-associated protein targets.
  • [MeSH-minor] Adenoma, Oxyphilic / genetics. Carcinoma, Papillary / genetics. Carcinoma, Renal Cell / genetics. Humans. Kidney Neoplasms / genetics. Microdissection. Phenotype. Sensitivity and Specificity. Specimen Handling. Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization. Wilms Tumor / genetics

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  • (PMID = 16327985.001).
  • [ISSN] 1019-6439
  • [Journal-full-title] International journal of oncology
  • [ISO-abbreviation] Int. J. Oncol.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Proteins
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50. Bahrami A, Schwartz MR, Ayala AG, Goldfarb RA, Brady JR, Takei H, Ro JY: Concurrent angiomyolipoma and two oncocytomas in the same kidney. Ann Diagn Pathol; 2007 Apr;11(2):132-6
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  • We report on a rare case of synchronous angiomyolipoma (AML) and 2 oncocytomas (OCs) in the same kidney of a 73-year-old woman.
  • During the course of a follow-up for a long-standing staghorn calculus in the left kidney, a 4-cm right suprarenal mass and a small solid nodule adjacent to a cyst in the midportion of the right kidney were radiographically discovered.
  • The suprarenal tumor was found to be an AML, and the small nodule was an OC (1.5 cm).
  • Among reported cases, conventional renal cell carcinoma, possibly reflecting its higher incidence, has been the most common concurrent tumor with AML.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Angiomyolipoma / pathology. Kidney Neoplasms / pathology. Neoplasms, Multiple Primary / pathology
  • [MeSH-minor] Aged. Antigens, Neoplasm. Biomarkers, Tumor / metabolism. Female. Humans. Melanoma-Specific Antigens. Neoplasm Proteins / metabolism. Nephrectomy. Tomography, X-Ray Computed

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  • (PMID = 17349574.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
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51. Lai G, Nemolato S, Lecca S, Parodo G, Medda C, Faa G: The role of immunohistochemistry in the diagnosis of hyalinizing clear cell carcinoma of the minor salivary gland: a case report. Eur J Histochem; 2008 Oct-Dec;52(4):251-4
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  • [Title] The role of immunohistochemistry in the diagnosis of hyalinizing clear cell carcinoma of the minor salivary gland: a case report.
  • [MeSH-major] Adenocarcinoma, Clear Cell / diagnosis. Immunohistochemistry / methods. Salivary Gland Neoplasms / diagnosis. Salivary Glands, Minor / pathology
  • [MeSH-minor] Adenoma, Oxyphilic / diagnosis. Biomarkers, Tumor / analysis. Carcinoma, Mucoepidermoid / diagnosis. Carcinoma, Renal Cell / diagnosis. Carcinoma, Renal Cell / secondary. Diagnosis, Differential. Female. Humans. Hyalin / metabolism. Keratins / analysis. Melanoma / diagnosis. Melanoma / secondary. Middle Aged. Myoepithelioma / diagnosis

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  • (PMID = 19109100.001).
  • [ISSN] 1121-760X
  • [Journal-full-title] European journal of histochemistry : EJH
  • [ISO-abbreviation] Eur J Histochem
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 68238-35-7 / Keratins
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52. Hornsby CD, Cohen C, Amin MB, Picken MM, Lawson D, Yin-Goen Q, Young AN: Claudin-7 immunohistochemistry in renal tumors: a candidate marker for chromophobe renal cell carcinoma identified by gene expression profiling. Arch Pathol Lab Med; 2007 Oct;131(10):1541-6
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  • This differential diagnosis is important because chromophobe RCC is malignant, whereas oncocytoma is benign.
  • OBJECTIVE: In a previous gene expression microarray analysis of renal tumor subtypes, we found the distal nephron markers claudin-7 and claudin-8 to be overexpressed in chromophobe RCC versus oncocytoma and other tumor subtypes.
  • CONCLUSIONS: Based on microarray and immunohistochemical data, we propose claudin-7 to be a candidate expression marker for distinguishing chromophobe RCC from other renal tumor subtypes, including the morphologically similar oncocytoma.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Carcinoma, Renal Cell / metabolism. Gene Expression. Gene Expression Profiling / methods. Kidney Neoplasms / metabolism. Membrane Proteins / metabolism
  • [MeSH-minor] Adenoma, Oxyphilic / diagnosis. Claudins. Diagnosis, Differential. Immunohistochemistry. RNA, Messenger / metabolism. RNA, Neoplasm / analysis

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  • (PMID = 17922590.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / 1 U54 CA119338-02
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Validation Studies
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CLDN7 protein, human; 0 / Claudins; 0 / Membrane Proteins; 0 / RNA, Messenger; 0 / RNA, Neoplasm
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53. Bernardini FP, Orcioni GF, Croxatto JO: Oncocytic carcinoma of the lacrimal gland in a patient with neurofibromatosis. Ophthal Plast Reconstr Surg; 2010 Nov-Dec;26(6):486-8
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  • [Title] Oncocytic carcinoma of the lacrimal gland in a patient with neurofibromatosis.
  • Oncocytic carcinoma (OCA) is rare, and although its occurrence in the lacrimal gland has been documented, clinical and histologic data are lacking.
  • The authors report the first case of OCA of the lacrimal gland histologically proven in a patient with neurofibromatosis (NF).
  • Orbital CT scan showed a mass in the lacrimal gland fossa infiltrating the globe, lateral rectus muscle, and bone.
  • Six months after the operation, the patient was alive, without evidence of recurrent or metastatic disease.
  • OCA is a high-grade neoplasm with infiltrative growth pattern and tendency to recur and metastasize.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Eye Neoplasms / pathology. Lacrimal Apparatus Diseases / pathology. Neurofibromatoses / pathology


54. Zhou CX, Gao Y: Oncocytoma of the salivary glands: a clinicopathologic and immunohistochemical study. Oral Oncol; 2009 Dec;45(12):e232-8
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  • We present a clinicopathologic and immunohistochemical study of 21 Chinese patients with oncocytoma of salivary gland origin, a rare benign tumour composed exclusively of large epithelial cells with eosinophilic granular cytoplasm (oncocytes).
  • In summary, clinical diagnosis for an oncocytoma is challenging for its similar features to other benign tumours.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Antibodies, Antinuclear / metabolism. Antibodies, Monoclonal / metabolism. Palatal Neoplasms / pathology. Parotid Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Child. China. Diagnosis, Differential. Female. Humans. Male. Microscopy, Electron. Middle Aged. Neoplasm Proteins / metabolism

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  • (PMID = 19796983.001).
  • [ISSN] 1879-0593
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies, Antinuclear; 0 / Antibodies, Monoclonal; 0 / MIB-1 antibody; 0 / Neoplasm Proteins
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55. Demasi AP, Furuse C, Altemani A, Junqueira JL, Oliveira PR, Araújo VC: Peroxiredoxin I is overexpressed in oncocytic lesions of salivary glands. J Oral Pathol Med; 2009 Jul;38(6):514-7
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  • RESULTS: Our results showed that Prx I is overexpressed in oncocytes regardless of the salivary gland lesion where they appear.
  • [MeSH-minor] Adenocarcinoma / enzymology. Adenocarcinoma / pathology. Adenolymphoma / enzymology. Adenolymphoma / pathology. Adenoma, Oxyphilic / enzymology. Adenoma, Oxyphilic / pathology. Antioxidants / analysis. Biomarkers / analysis. Carcinoma, Mucoepidermoid / enzymology. Carcinoma, Mucoepidermoid / pathology. Free Radical Scavengers / analysis. Gene Expression Regulation, Enzymologic. Granular Cell Tumor / enzymology. Granular Cell Tumor / pathology. Humans. Hydrogen Peroxide / analysis. Hyperplasia. Lysosomes / pathology. Metaplasia. Mitochondria / pathology. Reactive Oxygen Species / analysis. Salivary Gland Neoplasms / enzymology. Salivary Gland Neoplasms / pathology. Thyroid Gland / pathology

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  • (PMID = 19298244.001).
  • [ISSN] 1600-0714
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antioxidants; 0 / Biomarkers; 0 / Free Radical Scavengers; 0 / Reactive Oxygen Species; BBX060AN9V / Hydrogen Peroxide; EC 1.11.1.15 / Peroxiredoxins
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56. Zhang J, Kang SK, Wang L, Touijer A, Hricak H: Distribution of renal tumor growth rates determined by using serial volumetric CT measurements. Radiology; 2009 Jan;250(1):137-44
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  • [Title] Distribution of renal tumor growth rates determined by using serial volumetric CT measurements.
  • PURPOSE: To retrospectively determine the distribution of growth rates across different sizes and subtypes of renal cortical tumors by assessing tumor volume and maximum tumor diameter at serial volumetric computed tomographic (CT) examinations.
  • Fifty-three of 2304 patients (34 men, 19 women; mean age, 67 years +/- 10 [standard deviation; range, 39-88 years) who underwent nephrectomy from 1989 to 2006 did not receive preoperative chemotherapy or radiation therapy and underwent at least two preoperative contrast material-enhanced CT examinations (at least 3 months apart) with identical section thickness that was no more than one-fifth of longitudinal tumor diameter.
  • Tumor volume and maximum diameter were measured on CT scans.
  • Median tumor size was 2.9 cm (range, 1-12 cm).
  • No significant correlation was found between RDT and tumor initial volume, subtype, or grade.
  • Small renal tumors (<or=3.5 cm) were similar to larger tumors in subtype and growth rate.
  • Age at diagnosis correlated negatively with renal tumor growth rate (P = .03).
  • [MeSH-minor] Adenoma, Oxyphilic / pathology. Adenoma, Oxyphilic / radiography. Adenoma, Oxyphilic / surgery. Adult. Aged. Aged, 80 and over. Angiomyolipoma / pathology. Angiomyolipoma / radiography. Angiomyolipoma / surgery. Carcinoma, Papillary / pathology. Carcinoma, Papillary / radiography. Carcinoma, Papillary / surgery. Carcinoma, Renal Cell / pathology. Carcinoma, Renal Cell / radiography. Carcinoma, Renal Cell / surgery. Disease Progression. Female. Humans. Male. Mathematical Computing. Middle Aged. Neoplasm Staging. Prognosis. Retrospective Studies. Tumor Burden

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  • [Copyright] (c) RSNA, 2009.
  • [CommentIn] Radiology. 2013 Dec;269(3):949-50 [24261507.001]
  • [CommentIn] Radiology. 2009 Jul;252(1):314; author reply 314-5 [19561267.001]
  • [ErratumIn] Radiology. 2013 Dec;269(3):950
  • [ErratumIn] Radiology. 2009 Jul;252(1):318
  • (PMID = 19092093.001).
  • [ISSN] 1527-1315
  • [Journal-full-title] Radiology
  • [ISO-abbreviation] Radiology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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57. Barnabei A, Ferretti E, Baldelli R, Procaccini A, Spriano G, Appetecchia M: Hurthle cell tumours of the thyroid. Personal experience and review of the literature. Acta Otorhinolaryngol Ital; 2009 Dec;29(6):305-11
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  • The prognosis of the malignant type of the tumour is still under debate as some Authors have reported that Hurthle cell adenoma occasionally behaves like Hurthle cell carcinoma.
  • Aim of the present study was to evaluate previously reported data and personal experience on the clinical and pathological features of patients affected by Hurthle cell tumour that may predict disease progression and death.
  • In the literature, factors potentially associated with decreased survival were identified and include: age, disease stage, tumour size, extra-glandular invasion, lymph node disease, distant metastases, extensive surgery, radioiodine treatment.
  • From 1992 to 2003, the Authors identified 28 patients affected by Hurthle cell tumour, 9 with Hurthle cell adenoma and 19 with Hurthle cell carcinoma.
  • Mean age of patients affected by adenoma was 49.7 years (range 30-72) vs. 49.3 years (range 15-72) in Hurthle cell carcinoma patients.
  • At histology, 9 adenomas, 5 "minimally invasive" and 14 invasive carcinomas were found.
  • Relapse was not observed in any of the cases with adenoma.
  • None of the patients with Hurthle cell adenoma showed a relapse or death caused by the tumour.

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  • (PMID = 20463834.001).
  • [ISSN] 1827-675X
  • [Journal-full-title] Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale
  • [ISO-abbreviation] Acta Otorhinolaryngol Ital
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Italy
  • [Chemical-registry-number] Thyroid cancer, Hurthle cell
  • [Other-IDs] NLM/ PMC2868205
  • [Keywords] NOTNLM ; Hurthle cell adenoma / Hurthle cell carcinoma / Thyroid
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58. Suh I, Vriens MR, Guerrero MA, Griffin A, Shen WT, Duh QY, Clark OH, Kebebew E: Serum thyroglobulin is a poor diagnostic biomarker of malignancy in follicular and Hurthle-cell neoplasms of the thyroid. Am J Surg; 2010 Jul;200(1):41-6
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  • We compared Tg in malignant versus benign tumors by univariate and receiver-operator characteristic analyses.
  • There were no differences between malignant (n = 16) and benign (n = 23) lesions in Tg or any of the normalized indexes.
  • [MeSH-major] Adenocarcinoma, Follicular / pathology. Adenoma, Oxyphilic / pathology. Thyroglobulin / blood. Thyroid Neoplasms / blood. Thyroid Neoplasms / pathology

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  • [Copyright] Copyright (c) 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20637335.001).
  • [ISSN] 1879-1883
  • [Journal-full-title] American journal of surgery
  • [ISO-abbreviation] Am. J. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers; 9010-34-8 / Thyroglobulin
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59. McGinnis M: Metastatic Hurthle cell carcinoma and medical certification. Aviat Space Environ Med; 2007 Nov;78(11):1078-9
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  • Thyroglobulin can be a useful tumor marker for disease surveillance.
  • Disease impact on safety of flight is the primary aeromedical concern.
  • [MeSH-major] Adenoma, Oxyphilic / surgery. Thyroid Neoplasms / surgery. Work Capacity Evaluation

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  • (PMID = 18018444.001).
  • [ISSN] 0095-6562
  • [Journal-full-title] Aviation, space, and environmental medicine
  • [ISO-abbreviation] Aviat Space Environ Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 9010-34-8 / Thyroglobulin
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60. Jarząb M, Lange D: Endogenous avidin biotin activity (EABA) in thyroid pathology: immunohistochemical study. Thyroid Res; 2009 Apr 08;2(1):5
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  • MATERIALS AND METHODS: The immunohistochemical study was performed on paraffin-embedded specimens of surgically resected thyroid tissue from 97 patients with thyroid diseases: 65 patients with papillary carcinoma (PTC), 11 patients with nodular goiter in whom features of benign papillary hyperplasia were found, 9 with lymphocytic thyroiditis (LT), 8 with follicular adenoma, and 4 patients with follicular carcinoma.
  • RESULTS: Strong cytoplasmic EABA was observed in 56 of 65 (87.5%) PTC and in oxyphilic cells in 8 of 9 cases of LT.
  • Significant correlation between EABA in primary PTC tumor and EABA in lymph node metastases was stated.

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  • (PMID = 19351422.001).
  • [ISSN] 1756-6614
  • [Journal-full-title] Thyroid research
  • [ISO-abbreviation] Thyroid Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2678080
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61. Gorgone S, Campennì A, Calbo E, Catalfamo A, Sciglitano P, Sofia L, Niceta M, Borzì R, Calbo L: [Differentiated thyroid cancers]. G Chir; 2009 Jan-Feb;30(1-2):26-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adenoma, Oxyphilic / epidemiology. Adenoma, Oxyphilic / radiotherapy. Adenoma, Oxyphilic / secondary. Adenoma, Oxyphilic / surgery. Cell Differentiation. Combined Modality Therapy. Follow-Up Studies. Humans. Iodine Radioisotopes / therapeutic use. Italy / epidemiology. Lymph Node Excision. Lymphatic Metastasis. Prognosis. Retrospective Studies. Thyroidectomy. Thyroxine / therapeutic use

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  • (PMID = 19272228.001).
  • [ISSN] 0391-9005
  • [Journal-full-title] Il Giornale di chirurgia
  • [ISO-abbreviation] G Chir
  • [Language] ita
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Iodine Radioisotopes; Q51BO43MG4 / Thyroxine
  • [Number-of-references] 12
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62. Schachter LR, Cookson MS, Chang SS, Smith JA Jr, Dietrich MS, Jayaram G, Herrell SD: Second prize: frequency of benign renal cortical tumors and histologic subtypes based on size in a contemporary series: what to tell our patients. J Endourol; 2007 Aug;21(8):819-23
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  • [Title] Second prize: frequency of benign renal cortical tumors and histologic subtypes based on size in a contemporary series: what to tell our patients.
  • MATERIALS AND METHODS: Our prospectively collected database of all 482 patients who underwent partial or radical nephrectomy for a unilateral, unifocal, suspicious renal cortical tumor between January 2001 and October 2005 was reviewed.
  • The frequency of benign and malignant lesions was determined according to size, as was the incidence of the various histologic subtypes.
  • Of all lesions <or=4 cm, 26.3% were benign, whereas only 8.3% of the lesions >4 cm were benign.
  • For larger lesions, 10.9% of those between 4 and 7 cm and only 5.6% of those >7 cm were benign (P < 0.001).
  • Approximately one fourth (26.3%) of lesions <or=4 cm and 16.8% of lesions overall were benign, percentages higher than those reported in older series.
  • Importantly, there was a higher incidence of benign and papillary lesions and a lower incidence of clear-cell histology in smaller lesions.

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  • (PMID = 17867935.001).
  • [ISSN] 0892-7790
  • [Journal-full-title] Journal of endourology
  • [ISO-abbreviation] J. Endourol.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
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63. Sukov WR, Ketterling RP, Lager DJ, Carlson AW, Sinnwell JP, Chow GK, Jenkins RB, Cheville JC: CCND1 rearrangements and cyclin D1 overexpression in renal oncocytomas: frequency, clinicopathologic features, and utility in differentiation from chromophobe renal cell carcinoma. Hum Pathol; 2009 Sep;40(9):1296-303
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  • SUMMARY: Renal oncocytoma is a benign tumor occurring singly or as multiple synchronous lesions.
  • Of the 25 patients whose original tumor showed no cyclin D1 overexpression, 8 (32%) developed a subsequent renal oncocytoma.
  • None of 15 patients whose original tumor showed cyclin D1 overexpression had a subsequent renal oncocytoma (P = .016).
  • [MeSH-major] Adenoma, Oxyphilic / genetics. Carcinoma, Renal Cell / genetics. Cyclin D1 / genetics. Gene Rearrangement. Kidney Neoplasms / genetics
  • [MeSH-minor] Case-Control Studies. Chromosomes, Human, Pair 11 / metabolism. Cytogenetic Analysis / methods. Diagnosis, Differential. Female. Humans. Immunohistochemistry. In Situ Hybridization, Fluorescence. Karyotyping. Male. Nephrectomy. Translocation, Genetic. Tumor Cells, Cultured


64. Blanco L, Larrinaga G, Pérez I, López JI, Gil J, Agirregoitia E, Varona A: Acid, basic, and neutral peptidases present different profiles in chromophobe renal cell carcinoma and in oncocytoma. Am J Physiol Renal Physiol; 2008 Apr;294(4):F850-8
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  • Now, to gain insight into the reasons that lead the various RCC types to behave very differently with regard to aggressiveness and response to anticancer treatments, we analyzed subsets of chromophobe renal cell carcinoma (ChRCC), and renal oncocytoma (RO), a benign tumor; as well as different grades and stages of CCRCCs.
  • Particulate APN, APB, and APA activities were decreased in both ChRCC and RO (tumor vs. nontumor tissues).
  • Interestingly, activities were downregulated in a tumor-type specific way and the intensities of the decreases were stronger in the benign tumor than in the malignant type.
  • Moreover, when two key histopathological parameters for tumor prognosis (high vs. low stage and grade) were analyzed, increases of activity were also observed in several of these cell surface peptidases (APN, APB).
  • [MeSH-major] Adenoma, Oxyphilic / genetics. Carcinoma, Renal Cell / genetics. Kidney Neoplasms / genetics. Peptide Hydrolases / genetics
  • [MeSH-minor] Aged. Aged, 80 and over. DNA Primers. Female. Gene Expression Profiling. Humans. Hydrogen-Ion Concentration. Kinetics. Male. Middle Aged. Neoplasm Staging. Polymerase Chain Reaction


65. Terui K, Sakihara S, Kageyama K, Nigawara T, Takayasu S, Matsuhashi Y, Kon A, Yamamoto H, Ohyama C, Sasano H, Suda T: A case of adrenocortical oncocytoma occurring with aldosteronoma. J Clin Endocrinol Metab; 2010 Aug;95(8):3597-8
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  • [MeSH-major] Adenoma, Oxyphilic / pathology. Adrenal Cortex Neoplasms / pathology. Adrenocortical Adenoma / pathology. Neoplasms, Multiple Primary / pathology

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  • (PMID = 20685888.001).
  • [ISSN] 1945-7197
  • [Journal-full-title] The Journal of clinical endocrinology and metabolism
  • [ISO-abbreviation] J. Clin. Endocrinol. Metab.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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66. Hes O, Brunelli M, Michal M, Cossu Rocca P, Hora M, Chilosi M, Mina M, Boudova L, Menestrina F, Martignoni G: Oncocytic papillary renal cell carcinoma: a clinicopathologic, immunohistochemical, ultrastructural, and interphase cytogenetic study of 12 cases. Ann Diagn Pathol; 2006 Jun;10(3):133-9
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  • [MeSH-minor] Adenoma, Oxyphilic / diagnosis. Adult. Aged. Aged, 80 and over. Aneuploidy. Biomarkers, Tumor / analysis. Chromosome Deletion. Chromosomes, Human, Pair 17. Chromosomes, Human, Pair 7. Chromosomes, Human, Y / genetics. Cytoplasm / ultrastructure. Diagnosis, Differential. Female. Humans. In Situ Hybridization, Fluorescence. Interphase / genetics. Male. Middle Aged


67. Lin CC, Tsai MH, Huang CC, Hua CH, Tseng HC, Huang ST: Parotid tumors: a 10-year experience. Am J Otolaryngol; 2008 Mar-Apr;29(2):94-100
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  • Data including age, sex, clinical signs and symptoms, histologic findings, complications, malignant tumor stage, and prognosis were collected from medical charts.
  • RESULTS: Of the 271 patients who underwent parotidectomy, 229 (85%) had benign tumors, 33 (12%) had malignant tumors, and 9 had chronic inflammatory disease (3%).
  • The most common benign tumor was pleomorphic adenoma (51%), and the most common malignant tumor was mucoepidermoid carcinoma (3%).
  • The 5-year overall survival rate was 42%, and the disease-specific survival rate for malignant tumor was 72%.
  • Only disease stage was the statistically significant prognostic factor of malignancy.
  • Management of malignant tumors depends on tumor stage and histologic grade.
  • Advanced tumor stage is a predictor of poor outcome.
  • [MeSH-minor] Adenolymphoma / mortality. Adenolymphoma / pathology. Adenolymphoma / therapy. Adenoma, Oxyphilic / mortality. Adenoma, Oxyphilic / pathology. Adenoma, Oxyphilic / therapy. Adenoma, Pleomorphic / mortality. Adenoma, Pleomorphic / pathology. Adenoma, Pleomorphic / therapy. Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma / mortality. Carcinoma / pathology. Carcinoma / therapy. Child. Facial Paralysis / etiology. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neck Dissection. Neoplasm Recurrence, Local. Neoplasm Staging. Postoperative Complications. Prognosis. Radiotherapy, Adjuvant. Reoperation. Retrospective Studies

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  • (PMID = 18314019.001).
  • [ISSN] 0196-0709
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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68. Chang SL, Gonzalgo ML: Editorial comment. J Urol; 2010 Feb;183(2):459; discussion 459
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  • [MeSH-minor] Adenoma, Oxyphilic / classification. Adenoma, Oxyphilic / epidemiology. Adenoma, Oxyphilic / pathology. Humans. Incidence

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  • [CommentOn] J Urol. 2010 Feb;183(2):455-8 [20006852.001]
  • (PMID = 20006881.001).
  • [ISSN] 1527-3792
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Comment; Editorial
  • [Publication-country] United States
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69. Elliott DD, Pitman MB, Bloom L, Faquin WC: Fine-needle aspiration biopsy of Hurthle cell lesions of the thyroid gland: A cytomorphologic study of 139 cases with statistical analysis. Cancer; 2006 Apr 25;108(2):102-9
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  • [Title] Fine-needle aspiration biopsy of Hurthle cell lesions of the thyroid gland: A cytomorphologic study of 139 cases with statistical analysis.
  • BACKGROUND: Lesions of the thyroid gland composed of Hurthle cells encompass pathologic entities ranging from hyperplastic nodules with Hurthle cell metaplasia to Hurthle cell carcinomas.
  • Many cytologic features of Hurthle cell lesions that distinguish neoplastic Hurthle cell lesions requiring surgery from those that are benign and nonneoplastic have been described, but with variable usefulness.
  • A morphologic study was made of 139 Hurthle cell lesions of the thyroid gland and statistical analysis applied to identify a set of cytomorphologic features that distinguish benign Hurthle cell lesions (BHCL) from Hurthle cell neoplasms (HCN).
  • [MeSH-major] Adenoma / pathology. Adenoma, Oxyphilic / pathology. Oxyphil Cells / pathology. Thyroid Gland / pathology. Thyroid Neoplasms / pathology

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  • [Copyright] Copyright 2006 American Cancer Society.
  • (PMID = 16453320.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Colloids
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70. Shen SS, Krishna B, Chirala R, Amato RJ, Truong LD: Kidney-specific cadherin, a specific marker for the distal portion of the nephron and related renal neoplasms. Mod Pathol; 2005 Jul;18(7):933-40
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  • [MeSH-minor] Adenocarcinoma, Clear Cell / metabolism. Adenocarcinoma, Clear Cell / pathology. Adenoma, Oxyphilic / metabolism. Adenoma, Oxyphilic / pathology. Biomarkers / analysis. Carcinoma, Papillary / metabolism. Carcinoma, Papillary / pathology. Carcinoma, Renal Cell / metabolism. Carcinoma, Renal Cell / pathology. Diagnosis, Differential. Humans. Immunohistochemistry. Kidney Tubules / chemistry

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  • (PMID = 15696118.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Cadherins; 0 / FAT1 protein, human
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71. Sarma DP, Santos EE: Oncocytoma of the parotid gland. Ear Nose Throat J; 2009 May;88(5):914
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  • [Title] Oncocytoma of the parotid gland.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Parotid Gland / pathology. Parotid Neoplasms / pathology

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  • (PMID = 19444786.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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72. Brunelli M, Delahunt B, Gobbo S, Tardanico R, Eccher A, Bersani S, Cossu-Rocca P, Parolini C, Balzarini P, Menestrina F, Cheng L, Eble JN, Martignoni G: Diagnostic usefulness of fluorescent cytogenetics in differentiating chromophobe renal cell carcinoma from renal oncocytoma: a validation study combining metaphase and interphase analyses. Am J Clin Pathol; 2010 Jan;133(1):116-26
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  • [MeSH-major] Adenoma, Oxyphilic / diagnosis. Carcinoma, Renal Cell / diagnosis. Chromosome Aberrations. In Situ Hybridization, Fluorescence. Kidney Neoplasms / diagnosis
  • [MeSH-minor] DNA, Neoplasm / analysis. Diagnosis, Differential. Humans. Interphase / genetics. Metaphase / genetics. Tissue Array Analysis


73. Rubello D, Pelizzo MR, Casara D, Piotto A, Toniato A, Fig L, Gross M: Radio-guided surgery for non-131I-avid thyroid cancer. Thyroid; 2006 Nov;16(11):1105-11
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  • Sixty-six discrete nodules ranging from 6 to 45mm (mean tumor diameter, 18.4 +/- 8.5mm) were identified by both high-resolution ultrasound and (99m)Tc-sestamibi probe-guided RGS.
  • CONCLUSION: These data confirm our earlier observations that a (99m)Tc-sestamibi intraoperative gamma probe can be used to identify and guide resection of recurrent tumor and involved lymph nodes in locoregional metastases of nonradioiodine-avid thyroid cancer.
  • [MeSH-minor] Adenocarcinoma, Follicular / radionuclide imaging. Adenocarcinoma, Follicular / secretion. Adenocarcinoma, Follicular / surgery. Adenoma, Oxyphilic / radionuclide imaging. Adenoma, Oxyphilic / secretion. Adenoma, Oxyphilic / surgery. Adolescent. Adult. Aged. Female. Humans. Iodine Radioisotopes. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Recurrence, Local / radionuclide imaging. Neoplasm Recurrence, Local / surgery. Radiopharmaceuticals. Technetium Tc 99m Sestamibi. Thyroglobulin / blood

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  • (PMID = 17123337.001).
  • [ISSN] 1050-7256
  • [Journal-full-title] Thyroid : official journal of the American Thyroid Association
  • [ISO-abbreviation] Thyroid
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Iodine Radioisotopes; 0 / Radiopharmaceuticals; 9010-34-8 / Thyroglobulin; 971Z4W1S09 / Technetium Tc 99m Sestamibi
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74. Imaizumi M, Nakatsuka K: Oncocytoma of the peripunctum. Int Ophthalmol; 2005 Jun;26(3):111-3
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  • The tumor was completely excised including the lacrimal punctum and part of the canaliculus.
  • Histologically, the tumor had tubulo-papillary architecture and was composed of two layers of cuboidal cells.
  • The cytoplasm of the tumor cells was rich in eosinophilic granules.
  • CONCLUSION: Oncocytoma should be considered in differential diagnosis of a peripunctal mass in elderly patients.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Eye Neoplasms / pathology. Lacrimal Apparatus

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  • [Cites] Ophthalmologica. 1994;208(1):54-7 [8145989.001]
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  • (PMID = 17091220.001).
  • [ISSN] 0165-5701
  • [Journal-full-title] International ophthalmology
  • [ISO-abbreviation] Int Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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75. Gatto A, Falvo L, Sebastiani S, Roncolini G, Pinna G: Triple synchronous tumours of the urinary system with different histologies: a case report. Chir Ital; 2009 May-Jun;61(3):381-5
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  • We present the case report of a male patient with a diagnosis of synchronous kidney, bladder and prostate tumours with different histologies: renal oncocytoma, urothelial carcinoma of the bladder, and adenocarcinoma of the prostate.
  • [MeSH-minor] Adenocarcinoma / pathology. Adenoma, Oxyphilic / pathology. Aged. Carcinoma / pathology. Humans. Male. Risk Factors. Smoking / adverse effects. Treatment Outcome


76. Rosenkrantz AB, Hindman N, Fitzgerald EF, Niver BE, Melamed J, Babb JS: MRI features of renal oncocytoma and chromophobe renal cell carcinoma. AJR Am J Roentgenol; 2010 Dec;195(6):W421-7
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  • A central scar and segmental enhancement inversion (a recently described finding in which early contrast-enhanced images show relatively more enhanced and less enhanced intralesional components with inversion of their relative enhancement on later images) were observed by both readers in at least 10% of cases of both renal oncocytoma and of chromophobe RCC with no significant difference between the two entities (p = 0.2092-0.2960).
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Carcinoma, Renal Cell / pathology. Kidney Neoplasms / pathology. Magnetic Resonance Imaging / methods


77. Clark JR, Lai P, Hall F, Borglund A, Eski S, Freeman JL: Variables predicting distant metastases in thyroid cancer. Laryngoscope; 2005 Apr;115(4):661-7
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  • We present a series of patients with distant metastases to determine which patients are at risk of developing distant disease and to examine the significant prognostic variables.
  • Variables that predicted for development of distant disease were male sex, age, size, extrathyroidal extension, regional metastases, and elevated thyroglobulin.
  • Survival in patients without distant disease was significantly better than those with distant metastases (P < .001).
  • CONCLUSION: Although patients with thyroid cancer and distant metastases may live prolonged periods with disease, it does significantly impact on patient survival.
  • [MeSH-minor] Adenocarcinoma, Follicular / pathology. Adenocarcinoma, Follicular / secondary. Adenoma, Oxyphilic / pathology. Adenoma, Oxyphilic / secondary. Age Factors. Bone Neoplasms / secondary. Brain Neoplasms / secondary. Carcinoma, Papillary / pathology. Carcinoma, Papillary / secondary. Female. Follow-Up Studies. Forecasting. Humans. Lung Neoplasms / secondary. Male. Middle Aged. Neoplasm Recurrence, Local / pathology. Prognosis. Retrospective Studies. Risk Factors. Sex Factors. Survival Rate. Thyroglobulin / analysis

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  • (PMID = 15805877.001).
  • [ISSN] 0023-852X
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 9010-34-8 / Thyroglobulin
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78. Subramaniam RM, Durnick DK, Peller PJ: F-18 FDG PET/CT imaging of submandibular gland oncocytoma. Clin Nucl Med; 2008 Jul;33(7):472-4
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  • [Title] F-18 FDG PET/CT imaging of submandibular gland oncocytoma.
  • F-18 FDG PET/CT is used to evaluate head and neck malignancies, including salivary gland tumors.
  • We describe the FDG PET/CT features of a submandibular gland oncocytoma.
  • There was an intensely hypermetabolic left submandibular gland lesion that was suspected for a metastasis.
  • Ultrasound-guided fine needle aspirate of the lesion proved to be a submandibular gland oncocytoma.
  • [MeSH-major] Adenoma, Oxyphilic / diagnosis. Adenoma, Oxyphilic / radionuclide imaging. Fluorodeoxyglucose F18. Positron-Emission Tomography / methods. Radiopharmaceuticals. Submandibular Gland Neoplasms / diagnosis. Submandibular Gland Neoplasms / radionuclide imaging. Tomography, X-Ray Computed / methods
  • [MeSH-minor] Aged, 80 and over. Biopsy, Fine-Needle. Carcinoma, Squamous Cell / complications. Carcinoma, Squamous Cell / pathology. Humans. Lip Neoplasms / complications. Lip Neoplasms / pathology. Lung Neoplasms / complications. Lung Neoplasms / pathology. Male. Neoplasm Metastasis. Neoplasm Staging / methods

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  • (PMID = 18580232.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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79. Ong SC, Ng DC, Sundram FX: Initial experience in use of fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography in thyroid carcinoma patients with elevated serum thyroglobulin but negative iodine-131 whole body scans. Singapore Med J; 2005 Jun;46(6):297-301
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adenoma, Oxyphilic / radionuclide imaging. Adult. Aged. Aged, 80 and over. Carcinoma, Papillary / radionuclide imaging. Carcinoma, Papillary, Follicular / radionuclide imaging. Female. Humans. Iodine Radioisotopes. Male. Middle Aged. Neoplasm Recurrence, Local / radionuclide imaging. Retrospective Studies. Sensitivity and Specificity. Thyroglobulin / blood

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  • [CommentIn] Singapore Med J. 2005 Jun;46(6):257-8 [15902352.001]
  • (PMID = 15902358.001).
  • [ISSN] 0037-5675
  • [Journal-full-title] Singapore medical journal
  • [ISO-abbreviation] Singapore Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Singapore
  • [Chemical-registry-number] 0 / Iodine Radioisotopes; 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18; 9010-34-8 / Thyroglobulin
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80. Fontaine A, Thuret R, Garrigues V, Taourel P: [Post-transplant renal tumors: a report of three cases]. J Radiol; 2010 Apr;91(4):491-4
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  • Tumorectomy was undertaken for all three patients with successful results in two cases and return to hemodialysis in the third patient with a 4 cm tumor with mass effect on the collecting system.
  • [MeSH-minor] Adenoma, Oxyphilic / diagnosis. Adenoma, Oxyphilic / ultrasonography. Adult. Aged. Biopsy, Needle. Carcinoma, Renal Cell / diagnosis. Carcinoma, Renal Cell / ultrasonography. Early Detection of Cancer. Female. Follow-Up Studies. Humans. Male. Renal Dialysis. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 20514005.001).
  • [ISSN] 0221-0363
  • [Journal-full-title] Journal de radiologie
  • [ISO-abbreviation] J Radiol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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81. Arias LF, Bruneval P, Blanco J: Renin expression in adult renal epithelial tumors with granular cells. Pathol Res Pract; 2010 Nov 15;206(11):731-4
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  • After tumor resection, patients with renin expression and high blood pressure showed no hypertension remission.
  • [MeSH-minor] Adenoma, Oxyphilic / complications. Adenoma, Oxyphilic / metabolism. Adenoma, Oxyphilic / pathology. Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / metabolism. Cytoplasm / metabolism. Cytoplasm / pathology. Cytoplasmic Granules / metabolism. Female. Humans. Hypertension / complications. Immunoenzyme Techniques. Kidney / metabolism. Kidney / surgery. Kidney Tubules, Collecting / metabolism. Kidney Tubules, Collecting / pathology. Male. Middle Aged

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  • [Copyright] Copyright © 2010 Elsevier GmbH. All rights reserved.
  • (PMID = 20619546.001).
  • [ISSN] 1618-0631
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 3.4.23.15 / Renin; Oncocytoma, renal
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82. Sippel RS, Elaraj DM, Khanafshar E, Kebebew E, Duh QY, Clark OH: Does the presence of additional thyroid nodules on ultrasound alter the risk of malignancy in patients with a follicular neoplasm of the thyroid? Surgery; 2007 Dec;142(6):851-7; discussion 857.e1-2
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  • [Title] Does the presence of additional thyroid nodules on ultrasound alter the risk of malignancy in patients with a follicular neoplasm of the thyroid?
  • We sought to determine whether the presence of additional thyroid nodules on preoperative ultrasound decreased the risk of malignancy in a patient with a follicular neoplasm.
  • METHODS: Between January 2000 and November 2006, 325 patients underwent thyroidectomy with a fine needle aspiration diagnosis of either follicular neoplasm, Hürthle cell neoplasm, or indeterminate (not including suspicious for papillary thyroid cancer).
  • RESULTS: The rate of malignancy in our patient population was 20% (23% in follicular neoplasm, 19% in Hürthle cell neoplasm, 9% in indeterminate).
  • CONCLUSIONS: The presence of additional thyroid nodules on preoperative ultrasound is associated with a lower risk of malignancy in a patient with a follicular neoplasm.
  • [MeSH-minor] Adenoma, Oxyphilic / epidemiology. Adenoma, Oxyphilic / surgery. Adenoma, Oxyphilic / ultrasonography. Adult. Carcinoma, Papillary / epidemiology. Carcinoma, Papillary / surgery. Carcinoma, Papillary / ultrasonography. Female. Humans. Male. Middle Aged. Preoperative Care. Risk Assessment. Risk Factors. Thyroidectomy

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  • [ErratumIn] Surgery. 2008 Feb;143(2):302
  • (PMID = 18063067.001).
  • [ISSN] 1532-7361
  • [Journal-full-title] Surgery
  • [ISO-abbreviation] Surgery
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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83. Fiorini F: [A 'pretty' surprise...]. G Ital Nefrol; 2005 Jul-Aug;22(4):372-5
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  • The possibility of performing routine echography permitted the precocious diagnosis of bilateral kidney neoplasm and urothelial cancer.
  • [MeSH-minor] Adenoma, Oxyphilic / ultrasonography. Aged. Carcinoma / ultrasonography. Diagnosis, Differential. Humans. Male. Treatment Outcome. Ultrasonography, Doppler, Color. Urologic Neoplasms / ultrasonography

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  • (PMID = 16267798.001).
  • [ISSN] 0393-5590
  • [Journal-full-title] Giornale italiano di nefrologia : organo ufficiale della Società italiana di nefrologia
  • [ISO-abbreviation] G Ital Nefrol
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Italy
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84. Pusiol T, Franceschetti I, Scialpi M, Piscioli I, Tardio ML: Electron microscopy: the gold standard in the differential diagnosis of chromophobe renal cell carcinoma and oncocytoma. Anal Quant Cytol Histol; 2010 Feb;32(1):58-60
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  • [Title] Electron microscopy: the gold standard in the differential diagnosis of chromophobe renal cell carcinoma and oncocytoma.


85. Neuzillet Y, Lechevallier E, André M, de Fromont M, Nahon O, Coulange C: [Renal oncocytoma associated with renal cell carcinoma]. Prog Urol; 2005 Apr;15(2):312-4
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  • Renal oncocytoma is a benign tumour that can be associated with renal cell carcinoma in rare genetic syndromes.
  • The authors report the case of a 62-year-old patient with no medical history, in whom assessment of low back pain in 1999 demonstrated a 40 mm tumour of the lower pole of the left kidney.
  • [MeSH-major] Adenoma, Oxyphilic / diagnosis. Carcinoma, Renal Cell / diagnosis. Kidney Neoplasms / diagnosis. Neoplasms, Multiple Primary / diagnosis

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  • (PMID = 15999615.001).
  • [ISSN] 1166-7087
  • [Journal-full-title] Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie
  • [ISO-abbreviation] Prog. Urol.
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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86. Costa-Guda J, Tokura T, Roth SI, Arnold A: Mitochondrial DNA mutations in oxyphilic and chief cell parathyroid adenomas. BMC Endocr Disord; 2007 Oct 04;7:8
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  • [Title] Mitochondrial DNA mutations in oxyphilic and chief cell parathyroid adenomas.
  • We hypothesized that benign tumorigenesis of a slowly replicating tissue like the human parathyroid might constitute an especially fertile ground on which a selective advantage conferred by mtDNA mutation could be manifested and might contribute to the oxyphilic phenotype observed in a subset of parathyroid tumors.
  • METHODS: We sought acquired mitochondrial DNA mutations by sequencing the entire 16.6 kb mitochondrial genome of each of thirty sporadic parathyroid adenomas (18 chief cell and 12 oxyphil cell), eight independent, polyclonal, parathyroid primary chief cell hyperplasias plus corresponding normal control samples, five normal parathyroid glands, and one normal thyroid gland.
  • RESULTS: Twenty-seven somatic mutations were identified in 15 of 30 (9 of 12 oxyphil adenomas, 6 of 18 chief cell) parathyroid adenomas studied.
  • CONCLUSION: Features of the somatic mutations suggest that they may confer a selective advantage and contribute to the molecular pathogenesis of parathyroid adenomas.
  • Importantly, the statistically significant differences in mutation prevalence in oxyphil vs. chief cell adenomas also suggest that mtDNA mutations may contribute to the oxyphil phenotype.

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  • (PMID = 17916247.001).
  • [ISSN] 1472-6823
  • [Journal-full-title] BMC endocrine disorders
  • [ISO-abbreviation] BMC Endocr Disord
  • [Language] ENG
  • [Grant] United States / NIDCR NIH HHS / DE / T32 DE007302
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2099428
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87. Yamaguchi T, Kuroda N, Imamura Y, Hes O, Michal M, Sima R, Nakayama K, Sato N: Imprint cytologic features of chromophobe renal cell carcinoma morphologically resembling renal oncocytoma: is this an oncocytic variant of chromophobe renal cell carcinoma? Diagn Cytopathol; 2010 Jul;38(7):509-13
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  • Cytologically, renal tumor cells obtained from imprint cytology were isolated or arranged in small or monotonous population cells with abundant granular cytoplasm.
  • Immunocytochemically, the cytoplasm of almost all tumor cells was diffusely positive for vimentin and CK 7.
  • Additionally, tumor cells showed infiltration into some small renal veins covered by a single layer of endothelial cells.
  • Finally, we present a case of renal tumor morphologically resembling renal oncocytoma but genetically showing CRCC.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Carcinoma, Renal Cell / pathology. Cytological Techniques / methods. Kidney / pathology. Kidney Neoplasms / pathology
  • [MeSH-minor] Aged. Chromosomes, Human / genetics. Female. Humans. In Situ Hybridization, Fluorescence. Loss of Heterozygosity / genetics. Mutation / genetics. Von Hippel-Lindau Tumor Suppressor Protein / genetics


88. Prasad SR, Surabhi VR, Menias CO, Raut AA, Chintapalli KN: Benign renal neoplasms in adults: cross-sectional imaging findings. AJR Am J Roentgenol; 2008 Jan;190(1):158-64
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  • [Title] Benign renal neoplasms in adults: cross-sectional imaging findings.
  • OBJECTIVE: A broad spectrum of benign renal neoplasms in adults shows characteristic ontogeny, histology, and tumor biology.
  • Benign renal tumors are classified into renal cell tumors, metanephric tumors, mesenchymal tumors, and mixed epithelial and mesenchymal tumors.
  • Select benign tumors show characteristic anatomic distribution and imaging features.
  • However, because of overlapping of findings between benign and malignant renal tumors, histologic evaluation may be required to establish a definitive diagnosis.
  • CONCLUSION: We attempt to provide a comprehensive, contemporary review of benign renal neoplasms that occur in adults, focusing on cross-sectional imaging characteristics.
  • [MeSH-minor] Adenofibroma / diagnosis. Adenoma / diagnosis. Adenoma, Oxyphilic / diagnosis. Adult. Aged. Angiomyolipoma / diagnosis. Carcinoma, Renal Cell / diagnosis. Cross-Sectional Studies. Diagnosis, Differential. Female. Hemangioma / diagnosis. Humans. Leiomyoma / diagnosis. Magnetic Resonance Imaging. Male. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 18094306.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 62
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89. Giovanella L, Ceriani L, Ghelfo A, Maffioli M, Keller F: Preoperative undetectable serum thyroglobulin in differentiated thyroid carcinoma: incidence, causes and management strategy. Clin Endocrinol (Oxf); 2007 Oct;67(4):547-51
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  • [MeSH-major] Carcinoma, Papillary / blood. Neoplasm Recurrence, Local / blood. Thyroglobulin / blood. Thyroid Neoplasms / blood
  • [MeSH-minor] Adenocarcinoma, Follicular / blood. Adenocarcinoma, Follicular / radiotherapy. Adenocarcinoma, Follicular / surgery. Adenoma, Oxyphilic / blood. Adenoma, Oxyphilic / radiotherapy. Adenoma, Oxyphilic / surgery. Adult. Aged. Biomarkers / blood. Case-Control Studies. Female. Follow-Up Studies. Humans. Immunoradiometric Assay / methods. Incidence. Iodine Radioisotopes / therapeutic use. Male. Middle Aged. Radiopharmaceuticals / therapeutic use. Retrospective Studies. Sensitivity and Specificity. Thyroidectomy

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  • (PMID = 17561976.001).
  • [ISSN] 0300-0664
  • [Journal-full-title] Clinical endocrinology
  • [ISO-abbreviation] Clin. Endocrinol. (Oxf)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Iodine Radioisotopes; 0 / Radiopharmaceuticals; 9010-34-8 / Thyroglobulin
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90. Al-Saleem T, Balsara BR, Liu Z, Feder M, Testa JR, Wu H, Greenberg RE: Renal oncocytoma with loss of chromosomes Y and 1 evolving to papillary carcinoma in connection with gain of chromosome 7. Coincidence or progression? Cancer Genet Cytogenet; 2005 Nov;163(1):81-5
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  • Previous studies of hybrid renal tumors have been valuable for the understanding of the pathogenesis and progression pathways of renal cell neoplasm.
  • In this paper we describe the morphologic, immunohistochemical, and genetic features of 2 oncocytomas with evolving papillary renal cell carcinoma (PRCC) in a nephrectomy specimen of a 60-year old male.
  • The patient was referred for urologic oncology consultation after the incidental discovery of a renal tumor.
  • Papillary carcinoma nests were highlighted with cytokeratin 7 and vimentin positivity and were more prominent in the larger tumor.
  • [MeSH-major] Adenoma, Oxyphilic / genetics. Carcinoma, Papillary / genetics. Chromosome Aberrations. Chromosome Deletion. Chromosomes, Human, Pair 7. Chromosomes, Human, Y. Kidney Neoplasms / genetics
  • [MeSH-minor] Disease Progression. Humans. In Situ Hybridization, Fluorescence. Karyotyping. Male. Metaphase. Middle Aged

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  • (PMID = 16271962.001).
  • [ISSN] 0165-4608
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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91. Kazakov DV, Mikyskova I, Kutzner H, Simpson RH, Hes O, Mukensnabl P, Bouda J, Zamecnik M, Kinkor Z, Michal M: Hidradenoma papilliferum with oxyphilic metaplasia: a clinicopathological study of 18 cases, including detection of human papillomavirus. Am J Dermatopathol; 2005 Apr;27(2):102-10
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  • [Title] Hidradenoma papilliferum with oxyphilic metaplasia: a clinicopathological study of 18 cases, including detection of human papillomavirus.
  • Reported here are 18 cases of hidradenoma papilliferum with oxyphilic metaplasia.
  • Each presented clinically with a small, solitary tumor in the anogenital region.
  • Microscopically, in addition to classic histopathological features, in every case there was oxyphilic metaplasia of the constituent epithelial cells.
  • This finding could be likened to apocrine metaplasia, a term used in breast pathology.
  • Other histopathological findings observed in this series, analogous to benign breast disease, included sclerosing adenosis-like changes, atypical apocrine adenosis-like changes, changes corresponding to usual ductal epithelial hyperplasia, epitheliomatosis with a streaming growth pattern, lamprocyte-like changes, clear cell change of the myoepithelium, foamy histiocyte reaction, and stromal fibrosis.
  • Immunohistochemistry inferred that in the majority of cases oxyphilic metaplasia resulted from more lysosomes, whereas numerous mitochondria were detected in only 3 cases.
  • Using 2 different PCR methods we identified HPV in 4 of 15 cases of hidradenoma with oxyphilic metaplasia.
  • Oxyphilic metaplasia, areas with solid growth, and changes simulating atypical apocrine adenosis are rare and poorly recognized in hidradenoma papilliferum and may cause diagnostic difficulties; in our cases several submitting pathologists suspected malignancy.
  • The exact role of the HPV in etiology and pathogenesis of this neoplasm has yet to be determined.
  • [MeSH-minor] Adenoma, Sweat Gland / pathology. Adult. Aged. Animals. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Middle Aged. Papillomaviridae. Papillomavirus Infections / complications. Papillomavirus Infections / pathology. Polymerase Chain Reaction

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  • (PMID = 15798433.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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92. Gassler N, Haferkamp A, Flechtenmacher C, Hohenfellner M, Schirmacher P, Autschbach F: [Renal oncocytoma with metastasis from breast carcinoma: a contribution to the differential diagnosis of tumourous lesions of the kidney]. Pathologe; 2006 May;27(3):217-21
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  • The case of a renal oncocytoma involvement by metastasis from breast carcinoma in a 83-year-old woman is reported.
  • In conclusion, metastasis of breast carcinoma to a benign renal tumour is very rare.
  • [MeSH-major] Adenoma, Oxyphilic / secondary. Breast Neoplasms / pathology. Kidney Neoplasms / secondary. Neoplasm Metastasis

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  • (PMID = 16642392.001).
  • [ISSN] 0172-8113
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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93. Caloglu M, Yurut-Caloglu V, Altaner S, Huseyinova G, Unlu E, Karagol H, Uzal C: Oncocytic carcinoma of the parotid gland. Onkologie; 2006 Sep;29(8-9):388-90
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  • [Title] Oncocytic carcinoma of the parotid gland.
  • BACKGROUND: Oncocytic carcinoma is a rare tumor of major salivary glands.
  • Histochemical or electron microscopic confirmation of the oncocytic nature of the tumor cell is needed for differential diagnosis.
  • CASE REPORT: A 58-year old man presented with a recurrent mass in the left parotid gland with a prior diagnosis of monomorphic adenoma in the same localization which had been treated by tumor excision in July 2002.
  • Left superficial parotidectomy followed by radiotherapy into tumor bed and upper neck were carried out in September 2004.
  • CONCLUSION: For an accurate approach in the management of patients, oncocytic adenocarcinoma should be considered in the differential diagnosis of lesions of the parotid gland, most of which are benign.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Adenoma, Oxyphilic / therapy. Parotid Neoplasms / pathology. Parotid Neoplasms / therapy

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  • (PMID = 16974117.001).
  • [ISSN] 0378-584X
  • [Journal-full-title] Onkologie
  • [ISO-abbreviation] Onkologie
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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94. Roncaroli F, Scheithauer BW: Papillary tumor of the pineal region and spindle cell oncocytoma of the pituitary: new tumor entities in the 2007 WHO Classification. Brain Pathol; 2007 Jul;17(3):314-8
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  • [Title] Papillary tumor of the pineal region and spindle cell oncocytoma of the pituitary: new tumor entities in the 2007 WHO Classification.
  • We have reviewed the features of two recently described intracranial tumors, which have been formally recognized as distinct entities by the 2007 WHO Classification of Brain Tumours: Papillary tumor of the pineal region and spindle cell oncocytoma of the pituitary gland.
  • [MeSH-major] Adenoma, Oxyphilic / classification. Papilloma / classification. Pinealoma / classification. Pituitary Neoplasms / classification. Sarcoma / classification. World Health Organization

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  • (PMID = 17598824.001).
  • [ISSN] 1015-6305
  • [Journal-full-title] Brain pathology (Zurich, Switzerland)
  • [ISO-abbreviation] Brain Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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95. Wiseman SM, Melck A, Masoudi H, Ghaidi F, Goldstein L, Gown A, Jones SJ, Griffith OL: Molecular phenotyping of thyroid tumors identifies a marker panel for differentiated thyroid cancer diagnosis. Ann Surg Oncol; 2008 Oct;15(10):2811-26
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  • The objective of this work was to evaluate the molecular phenotype of differentiated thyroid cancer (DTC) and benign thyroid lesions to identify molecular markers that allow for accurate thyroid cancer diagnosis.
  • METHODS: Tissue microarrays consisting of 100 benign and 105 malignant thyroid lesions, plus 24 lymph node samples, were stained for a panel of 57 molecular markers.
  • Significant associations between marker staining and tumor pathology (DTC versus benign) were determined using contingency table and Mann-Whitney U (MU) tests.
  • Of these, in DTC compared with benign thyroid tumors, 8 markers were downregulated and 27 upregulated.
  • Using the entire molecular marker panel, a Random Forests algorithm was able to classify tumors as DTC or benign with an estimated sensitivity of 87.9%, specificity of 94.0%, and an accuracy of 91.0%.
  • CONCLUSION: Evaluation of the DTC and benign thyroid tumor molecular phenotype has allowed for identification of a marker panel, composed of both established and novel markers, useful for thyroid cancer diagnosis.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Thyroid Neoplasms / diagnosis. Thyroid Neoplasms / metabolism
  • [MeSH-minor] Adenocarcinoma, Follicular / diagnosis. Adenocarcinoma, Follicular / metabolism. Adenoma, Oxyphilic / diagnosis. Adenoma, Oxyphilic / metabolism. Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Papillary / diagnosis. Carcinoma, Papillary / metabolism. Cell Differentiation. Female. Humans. Immunoenzyme Techniques. Male. Middle Aged. Phenotype. Prognosis. Tissue Array Analysis

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  • (PMID = 18612701.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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96. Radopoulos D, Tzakas K, Tahmatzopoulos A: A rare case of renal oncocytoma associated with erythrocytosis: case report. BMC Urol; 2006;6:26
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  • BACKGROUND: Oncocytomas are benign tumors of the kidney that are usually diagnosed postoperatively due to differential diagnostic problems from renal cell carcinoma.
  • CASE PRESENTATION: In this case report we present a unique case of a right lower pole oncocytoma associated with erythrocytosis.
  • [MeSH-major] Adenoma, Oxyphilic / complications. Adenoma, Oxyphilic / diagnosis. Kidney Neoplasms / complications. Kidney Neoplasms / diagnosis. Polycythemia / complications. Polycythemia / diagnosis

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  • [Cites] J Urol. 2004 Mar;171(3):1066-70 [14767272.001]
  • [Cites] Eur Urol. 1992;21(2):160-3 [1499617.001]
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  • (PMID = 16995951.001).
  • [ISSN] 1471-2490
  • [Journal-full-title] BMC urology
  • [ISO-abbreviation] BMC Urol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1590043
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97. Kutikov A, Fossett LK, Ramchandani P, Tomaszewski JE, Siegelman ES, Banner MP, Van Arsdalen KN, Wein AJ, Malkowicz SB: Incidence of benign pathologic findings at partial nephrectomy for solitary renal mass presumed to be renal cell carcinoma on preoperative imaging. Urology; 2006 Oct;68(4):737-40
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  • [Title] Incidence of benign pathologic findings at partial nephrectomy for solitary renal mass presumed to be renal cell carcinoma on preoperative imaging.
  • OBJECTIVES: To determine the incidence of benign pathologic findings at partial nephrectomy for a solitary renal lesion when preoperative imaging is reviewed by an experienced team of academic genitourinary radiologists.
  • METHODS: From 1996 to 2004, 143 patients underwent resection of a solitary renal lesion for presumed renal cell carcinoma amenable to partial nephrectomy.
  • RESULTS: Of the 143 solitary masses resected, 23 revealed benign pathologic findings (16.1%).
  • Ten lesions (43.5%) were angiomyolipomas (AMLs), eight (34.8%) were oncocytomas, three (13.0%) were benign Bosniak-type cysts, and one each was a low-grade spindle cell lesion most consistent with mesoblastic nephroma, and a metanephric adenoma.
  • CONCLUSIONS: A significant fraction of small solitary renal masses presumed to be renal cell carcinoma had benign pathologic findings on resection, despite thorough expert radiologic review.
  • [MeSH-minor] Adenoma / epidemiology. Adenoma / pathology. Adenoma, Oxyphilic / epidemiology. Adenoma, Oxyphilic / pathology. Adult. Angiomyolipoma / epidemiology. Angiomyolipoma / pathology. Humans. Incidence. Nephrectomy. Nephroma, Mesoblastic / epidemiology. Nephroma, Mesoblastic / pathology

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  • [CommentIn] Nat Clin Pract Urol. 2007 Jul;4(7):360-1 [17487144.001]
  • (PMID = 17070344.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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98. Argüelles Salido E, Marcilla Plaza D, Medina López R, Congregado Ruiz B, Campoy Martínez P, Cayuela Domínguez A: [Renal oncocytoma. Review of our 22 patients]. Actas Urol Esp; 2006 Jun;30(6):583-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Renal oncocytoma (OR) is a benign tumor.
  • We try to find out the rate of multifocality, bilateralism and other tumor association, and the number of neoplasms originally diagnosed as OR before surgery.
  • Tumor mean size was 4.64 cm (1-12.5 cm).
  • All cases presented a benign evolution.
  • [MeSH-major] Adenoma, Oxyphilic. Kidney Neoplasms

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  • (PMID = 16921835.001).
  • [ISSN] 0210-4806
  • [Journal-full-title] Actas urologicas españolas
  • [ISO-abbreviation] Actas Urol Esp
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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99. Li G, Gentil-Perret A, Lambert C, Genin C, Tostain J: S100A1 and KIT gene expressions in common subtypes of renal tumours. Eur J Surg Oncol; 2005 Apr;31(3):299-303
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Biomarkers, Tumor / analysis. Gene Expression Regulation, Neoplastic. Kidney Neoplasms / chemistry. Proto-Oncogene Proteins c-kit / analysis. S100 Proteins / analysis
  • [MeSH-minor] Adenocarcinoma, Clear Cell / chemistry. Adenoma, Oxyphilic / chemistry. Carcinoma, Papillary / chemistry. Carcinoma, Renal Cell / chemistry. Cell Line, Tumor. Humans. Reverse Transcriptase Polymerase Chain Reaction

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  • (PMID = 15780567.001).
  • [ISSN] 0748-7983
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / S100 Proteins; 146909-89-9 / S100A11 protein, human; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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100. Chamnanrabiabkij E, Welch A, Jayapaul MK, Perros P: Detection of Hurthle cell carcinoma using sestamibi. Thyroid; 2008 May;18(5):575-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenoma, Oxyphilic / radionuclide imaging. Radiopharmaceuticals. Technetium Tc 99m Sestamibi. Thyroid Neoplasms / radionuclide imaging

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  • (PMID = 18044993.001).
  • [ISSN] 1050-7256
  • [Journal-full-title] Thyroid : official journal of the American Thyroid Association
  • [ISO-abbreviation] Thyroid
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
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