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3. Odashiro M, Lima MG, Miiji LN, Odashiro DN, Carvalho GV, Prates Campos JC, Odashiro AN: Infiltrating syringomatous adenoma of the nipple. Breast J; 2009 Jul-Aug;15(4):414-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Infiltrating syringomatous adenoma of the nipple.
  • Infiltrating syringomatous adenoma of the nipple is a rare, benign, locally invasive tumor with recurrence potential, showing sweat duct differentiation.
  • Histopathologically, it must be distinguished from florid papillomatosis, adenosquamous carcinoma, adenoid cystic carcinoma and sclerosing syringomatous carcinoma.
  • A 44-year-old woman presented with pain on the right nipple for 7 days.
  • On physical exam there was an irregular nodule on nipple area with edema.
  • The ultrasound showed a hypoechoic irregular nodule measuring 7.5 mm in the nipple area.
  • At the periphery, the ducts invaded muscular fibers of the nipple.
  • [MeSH-major] Adenoma / surgery. Breast Neoplasms / pathology. Breast Neoplasms / surgery. Nipples / pathology. Syringoma / surgery

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  • (PMID = 19470133.001).
  • [ISSN] 1524-4741
  • [Journal-full-title] The breast journal
  • [ISO-abbreviation] Breast J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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4. Riaz N, Khan SM, Idrees R, Kayani N: Infiltrating syringomatous adenoma of nipple. J Coll Physicians Surg Pak; 2008 Jul;18(7):438-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Infiltrating syringomatous adenoma of nipple.
  • Infiltrating syringomatous adenoma of the nipple is a rare, benign lesion with distinct clinical and histological features.
  • Important differential diagnosis include nipple adenoma, tubular carcinoma and adenosquamous carcinoma.
  • [MeSH-major] Adenoma / pathology. Breast Neoplasms / pathology. Nipples

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  • (PMID = 18760070.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
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5. Ishii N, Kusuhara M, Yasumoto S, Hashimoto T: Adenoma of the nipple in a Japanese man. Clin Exp Dermatol; 2007 Jul;32(4):448-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenoma of the nipple in a Japanese man.
  • [MeSH-major] Adenoma / pathology. Breast Neoplasms / pathology. Breast Neoplasms, Male / pathology. Nipples / pathology

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  • (PMID = 17362232.001).
  • [ISSN] 0307-6938
  • [Journal-full-title] Clinical and experimental dermatology
  • [ISO-abbreviation] Clin. Exp. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
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6. Kijima Y, Matsukita S, Yoshinaka H, Owaki T, Aikou T: Adenoma of the nipple: report of a case. Breast Cancer; 2006;13(1):95-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenoma of the nipple: report of a case.
  • We report a case of an adenoma of the nipple in a 33-year-old Japanese woman who presented with a 2-year history of itching, eczema, and discharge from the left nipple.
  • We performed a tumor resection with preservation of the nipple.
  • The histological diagnosis was adenoma of the nipple.
  • The patient was left with a cosmetically well-preserved nipple.
  • [MeSH-major] Adenoma / pathology. Breast Neoplasms / pathology. Nipples / pathology

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  • (PMID = 16518068.001).
  • [ISSN] 1340-6868
  • [Journal-full-title] Breast cancer (Tokyo, Japan)
  • [ISO-abbreviation] Breast Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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7. Tao W, Kai F, Yue Hua L: Nipple adenoma in an adolescent. Pediatr Dermatol; 2010 Jul-Aug;27(4):399-401
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  • [Title] Nipple adenoma in an adolescent.
  • Nipple adenoma is a rare tumor of the breast which usually appears in middle age women and rarely in adolescents.
  • We describe a 15-year-old female diagnosed with nipple adenoma.
  • Nipple adenoma is a benign neoplasia which should be recognized to avoid confusion with breast cancer.

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  • (PMID = 20653865.001).
  • [ISSN] 1525-1470
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Carcinoembryonic Antigen
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8. Page RN, Dittrich L, King R, Boulos F, Page DL: Syringomatous adenoma of the nipple occurring within a supernumerary breast: a case report. J Cutan Pathol; 2009 Nov;36(11):1206-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Syringomatous adenoma of the nipple occurring within a supernumerary breast: a case report.
  • Originally described by Rosen in 1983, syringomatous nipple adenoma (SAN) is a tumor of disputed histogenesis, which can be problematic both diagnostically and therapeutically.
  • [MeSH-major] Adenoma / pathology. Breast Neoplasms / pathology. Nipples / pathology. Sweat Gland Neoplasms / pathology. Syringoma / pathology

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  • (PMID = 19469876.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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9. Parajuly SS, Peng YL, Zhu M, Gang YZ, Gyawali S: Nipple adenoma of the breast: sonographic imaging findings. South Med J; 2010 Dec;103(12):1280-1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nipple adenoma of the breast: sonographic imaging findings.
  • [MeSH-major] Adenoma / ultrasonography. Breast Neoplasms / ultrasonography. Nipples / ultrasonography

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  • (PMID = 21037518.001).
  • [ISSN] 1541-8243
  • [Journal-full-title] Southern medical journal
  • [ISO-abbreviation] South. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
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10. Da Costa D, Taddese A, Cure ML, Gerson D, Poppiti R Jr, Esserman LE: Common and unusual diseases of the nipple-areolar complex. Radiographics; 2007 Oct;27 Suppl 1:S65-77
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Common and unusual diseases of the nipple-areolar complex.
  • The nipple-areolar complex is often best evaluated as a separate region of the breast.
  • Because of the intricacy of the anatomic structures and their superficial position, the diagnostic techniques required for optimal evaluation of the nipple-areolar complex differ from those routinely used to evaluate the whole breast.
  • For accurate diagnosis, familiarity with a wide range of appearances of the normal anatomy, including congenital anomalies (eg, supernumerary nipples), is necessary, as is a thorough knowledge of the features of the benign and malignant processes that commonly occur in the nipple-areolar complex.
  • Benign abnormalities may include mammary duct ectasia, nipple calcifications, cutaneous horn of the nipple, abscess of the Montgomery gland, and nipple adenoma.
  • Some conditions, such as nipple retraction and inversion, may have either a benign or a malignant cause.

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  • [Copyright] Copyright RSNA, 2007.
  • (PMID = 18180236.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 33
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11. Sarma DP, Stevens T: Infiltrating syringomatous eccrine adenoma of the nipple: a case report. Cases J; 2009;2:9118
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Infiltrating syringomatous eccrine adenoma of the nipple: a case report.
  • BACKGROUND: Differential diagnosis for a nodule in the nipple or subareolar area of woman includes both primary neoplasms of breast as well as those from skin and adnexae.
  • CASE PRESENTATION: A 32-year-old woman presented with a painless 0.5 cm subareolar nodule of her left nipple that she had noticed for several months, with no associated nipple discharge.
  • The infiltrating syringomatous adenoma of the nipple occurs almost exclusively in women of all ages and is cured by simple excision.
  • Microscopic appearance of such a rare benign infiltrating neoplasm of eccrine duct origin occurring in woman's breast should not be misinterpreted as more common infiltrating primary breast carcinoma.
  • CONCLUSION: Infiltrating eccrine syringomatous adenoma should be included in the differential diagnosis of a nipple or subareolar nodule occurring in woman.

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  • [Cites] Surg Gynecol Obstet. 1966 Jun;122(6):1289-94 [5941852.001]
  • [Cites] Breast J. 2004 Sep-Oct;10(5):443-7 [15327500.001]
  • [Cites] Am J Surg Pathol. 1983 Dec;7(8):739-45 [6660349.001]
  • [Cites] Clin Radiol. 1993 Jan;47(1):62-4 [8381340.001]
  • [Cites] Arch Pathol Lab Med. 2003 Mar;127(3):e155-6 [12653606.001]
  • (PMID = 20062695.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2803915
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12. Sato T, Muto I, Hasegawa M, Aono T, Okada T, Tamura T, Sakai T: A rare case of invasive ductal carcinoma with hyperprolactinemia. Breast Cancer; 2007;14(3):302-6
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  • We report here a rare form of invasive ductal carcinoma composed of a mass protruding from the tip of the nipple in a 43-year-old woman with hyperprolactinemia.
  • She presented with a mass on the left nipple that had been growing for 6 months.
  • Morphologically, the mass resembled adenoma of the nipple.
  • Another mass was located in the subareolar region.
  • Histopathologically, the tumor of the nipple was invasive ductal carcinoma, which had extended intraductally from another invasive ductal carcinoma in the subareolar region, and had infiltrated the epidermis of the nipple (Paget's disease).
  • Postoperatively, the plasma prolactin level was abnormally high, while the plasma estradiol level was quite low, although macro-pituitary adenoma was not detected by MRI.


13. Aftab K, Idrees R: Nipple adenoma of breast: a masquerader of malignancy. J Coll Physicians Surg Pak; 2010 Jul;20(7):472-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nipple adenoma of breast: a masquerader of malignancy.
  • ABSTRACT Nipple adenoma is a benign condition simulating malignancy such as breast carcinoma and/or Paget's disease clinically.
  • In this study 19 cases diagnosed as nipple adenoma over a period of 14 years are described.
  • [MeSH-major] Adenoma / diagnosis. Breast Neoplasms / diagnosis. Nipples

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  • (PMID = 20642949.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Pakistan
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14. Sanati S, Leonard M, Khamapirad T, Eltorky MA: Nodular mucinosis of the breast: a case report with pathologic, ultrasonographic, and clinical findings and review of the literature. Arch Pathol Lab Med; 2005 Mar;129(3):e58-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This benign mass usually presents clinically as a poorly circumscribed, subareolar, myxoid mass in young female patients.
  • Clinical breast examination demonstrated a 1 cm "rubbery" mass directly under and continuous with the left nipple.
  • The skin that covered the mass had an edematous and irregular appearance without erythema or drainage from the nipple.
  • Ultrasonography demonstrated a 1-cm, nonintraductal, circumscribed, homogeneous, isoechoic mass that was continuous or part of the base of the left nipple.
  • These findings suggested a benign breast lesion, including a fibroadenoma or nipple adenoma.

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  • (PMID = 15737051.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 15
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15. Clune JE, Kozakewich HP, VanBeek CA, Labow BI, Greene AK: Nipple adenoma in infancy. J Pediatr Surg; 2009 Nov;44(11):2219-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nipple adenoma in infancy.
  • We report the first patient with a nipple adenoma presenting in infancy.
  • Nipple adenoma is a benign lesion typically affecting women between 45 and 55 years of age.
  • Management of children with nipple adenoma requires consideration for breast development; excision before maturity may cause nipple-areola deformity or injury to the breast bud.
  • [MeSH-major] Adenoma / pathology. Adenoma / surgery. Breast Neoplasms / pathology. Breast Neoplasms / surgery. Nipples / pathology

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  • (PMID = 19944237.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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16. Oo KZ, Xiao PQ: Infiltrating syringomatous adenoma of the nipple: clinical presentation and literature review. Arch Pathol Lab Med; 2009 Sep;133(9):1487-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Infiltrating syringomatous adenoma of the nipple: clinical presentation and literature review.
  • Infiltrating syringomatous adenoma of the nipple is a rare neoplasm of the breast.
  • Syringomatous adenoma of the nipple is often misdiagnosed because clinical examination and mammographic findings of syringomatous adenoma of the nipple mimic carcinoma.
  • Despite its benign behavior, syringomatous adenoma of the nipple usually shows infiltrative expansile proliferation into adjacent tissue and underlying breast tissue.
  • Histologically and clinically, syringomatous adenoma of the nipple is often confused with tubular carcinoma as well as low-grade adenosquamous carcinoma of the breast.

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  • (PMID = 19722761.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 16
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17. Yang GZ, Li J, Ding HY: [Nipple adenoma: report of 18 cases with review of literatures]. Zhonghua Bing Li Xue Za Zhi; 2009 Sep;38(9):614-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Nipple adenoma: report of 18 cases with review of literatures].
  • OBJECTIVE: To investigate the clinicopathological and immunohistochemical features, diagnosis and differential diagnosis of nipple adenoma of the breast.
  • METHODS: Morphological observation and immunohistochemistry were applied to 18 cases of nipple adenoma with a review of the related literatures.
  • CONCLUSIONS: Nipple adenoma is an infrequent type of benign breast neoplasm, presenting as sclerosing papilloma, papillomatosis or florid sclerosing adenosis.
  • [MeSH-major] Adenoma / pathology. Breast Neoplasms / pathology. Nipples / pathology

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  • (PMID = 20079190.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] China
  • [Chemical-registry-number] 0 / CK-34 beta E12; 0 / Keratin-5; 68238-35-7 / Keratins
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18. Niu Y, Fu XL, Yu Y, Wang PP, Cao XC: Intra-operative frozen section diagnosis of breast lesions: a retrospective analysis of 13,243 Chinese patients. Chin Med J (Engl); 2007 Apr 20;120(8):630-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Six types (false invasion, peri-papilloma, adenoma of nipple duct, florid adenosis, sclerosing adenosis, and granulose cell tumor) of lesions may lead to false positive, and four types (morphological changes responding chemotherapy, well differentiated papillary carcinoma, invasive lobular carcinoma, and tubular carcinoma) to a false negative.
  • Gross and microscopic findings may be inconsistent in two types of lesions (radial scar and florid adenosis) microscopic and clinical findings in three types (ganulomatous mastitis mammary, duct ectasia, and fat necrosis), and three types (abundant fat or sclerous tissues; borderline lesions and changes of post-chemotherapy) were likely wrongly classified.

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  • (PMID = 17517175.001).
  • [ISSN] 0366-6999
  • [Journal-full-title] Chinese medical journal
  • [ISO-abbreviation] Chin. Med. J.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
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19. Singh SS, Velusami SD: Syringomatous adenoma of the nipple: report of a case. Indian J Pathol Microbiol; 2007 Oct;50(4):808-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Syringomatous adenoma of the nipple: report of a case.
  • Syringomatous adenoma of the nipple is a rarely encountered neoplasm of the breast with histological features similar to eccrine syringoma of the skin.
  • We report a case of syringomatous adenoma of the nipple in a postmenopausal diabetic woman who was incidentally found to have a subareolar mass in her right breast.
  • Histopathological examination showed features of syringomatous adenoma of the nipple.

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  • (PMID = 18306564.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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20. Kadowaki M, Nagashima T, Sakata H, Sakakibara M, Sangai T, Nakamura R, Fujimoto H, Arai M, Onai Y, Nagai Y, Miyazawa Y, Miyazaki M: Ectopic breast tissue in axillary lymph node. Breast Cancer; 2007;14(4):425-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The patient is a 48-year-old woman who had an adenoma of the nipple removed 10 years previously.

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  • (PMID = 17986810.001).
  • [ISSN] 1880-4233
  • [Journal-full-title] Breast cancer (Tokyo, Japan)
  • [ISO-abbreviation] Breast Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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21. Matsubayashi RN, Adachi A, Yasumori K, Muranaka T, Ikejiri K, Yahara T, Takeshita M: Adenoma of the nipple: correlation of magnetic resonance imaging findings with histologic features. J Comput Assist Tomogr; 2006 Jan-Feb;30(1):148-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenoma of the nipple: correlation of magnetic resonance imaging findings with histologic features.
  • Adenoma of the nipple (nipple adenoma) is a rare breast tumor that can show various histologic features.
  • We present magnetic resonance (MR) and other imaging findings of a case of nipple adenoma and correlate them with detailed histologic features of the tumor.
  • [MeSH-major] Adenoma / diagnosis. Breast Neoplasms / diagnosis. Magnetic Resonance Imaging. Nipples / pathology

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  • (PMID = 16365591.001).
  • [ISSN] 0363-8715
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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22. Dillon DA, Lester SC: Lesions of the Nipple. Surg Pathol Clin; 2009 Jun;2(2):391-412
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lesions of the Nipple.
  • Because of the singular anatomic structure of the nipple, some breast lesions only occur at this site.
  • The overlying skin includes normal Toker cells near the duct orifices.
  • Ductal carcinoma in situ (DCIS) may involve nipple skin by direct extension from the underlying ducts (Paget disease of the nipple).
  • The numerous skin appendages (eg, sebaceous, apocrine, and eccrine glands(1)) in the nipple and areola are the likely origin of syringomatous adenomas.
  • At the duct orifices, the normal squamous epithelium dips into the breast for a short distance and abruptly transitions to glandular luminal and myoepithelial cells.
  • With age, the lactiferous sinuses are subject to weakened duct walls, inspissated secretions, and rupture, which result in the inflammatory masses or nipple discharge associated with duct ectasia.
  • Superficial epithelial proliferations within the large lactiferous sinuses form nipple adenomas, and deeper proliferations often result in large-duct papillomas.
  • The proximity of these lesions to the skin results in the majority of them presenting as palpable masses, skin changes, or nipple discharge.
  • Biopsy specimens from these lesions may be small, superficial, or fragmented because of concern about maintaining the cosmetic appearance of the nipple and areola.

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  • [Copyright] Copyright © 2009 Elsevier Inc. All rights reserved.
  • (PMID = 26838328.001).
  • [ISSN] 1875-9181
  • [Journal-full-title] Surgical pathology clinics
  • [ISO-abbreviation] Surg Pathol Clin
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Duct ectasia / Nipple / Nipple adenoma / Paget disease / Papilloma / Squamous metaplasia of lactiferous ducts / Syringomatous adenoma / Toker cells
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23. Kinkor Z, Skálová A, Michal M, Janousek M, Kheck M: [Metastasing and relapsing "low grade" adenosquamous metaplastic breast cancer--is there a really indolent lesion? A description of three cases and review of literature]. Ceska Gynekol; 2005 May;70(3):211-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Low-grade adenosquamous carcinoma, however, has nothing to do with syringomatous adenoma of the nipple, which is a benign tumor of the skin adnexa.


24. Kono S, Kurosumi M, Simooka H, Kawanowa K, Takei H, Suemasu K: Nipple adenoma found in a mastectomy specimen: report of a case with special regard to the proliferation pattern. Breast Cancer; 2007;14(2):234-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nipple adenoma found in a mastectomy specimen: report of a case with special regard to the proliferation pattern.
  • We report a case of nipple adenoma incidentally found in a mastectomy specimen, and describe its unique histological appearance and the immunohistochemical distribution of Ki-67 positive tumor cells.
  • A 45-year-old woman with no symptoms or sign related to the nipple had a left mastectomy for invasive breast cancer.
  • A small nipple adenoma, 7 mm in size, was incidentally recognized in the nipple of the resected breast.
  • Histologically, the tumor in the nipple was composed of numerous proliferative ducts with a tubular and florid papillomatous appearance.
  • Many demarcations between squamous cells of the epidermis and tumor cells were recognized in the summit as well as the lateral wall of the nipple.
  • Based on these proliferative patterns, the symptoms and clinical signs related to the nipple that are often found in patients with nipple adenoma are thought to be associated with the destruction of the epidermis of the nipple by the invasion of benign tumor cells with high proliferative activity.
  • [MeSH-major] Adenoma / pathology. Breast Neoplasms / pathology. Mastectomy. Nipples / pathology

  • MedlinePlus Health Information. consumer health - Breast Cancer.
  • MedlinePlus Health Information. consumer health - Mastectomy.
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  • (PMID = 17485911.001).
  • [ISSN] 1340-6868
  • [Journal-full-title] Breast cancer (Tokyo, Japan)
  • [ISO-abbreviation] Breast Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Ki-67 Antigen
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25. Tuveri M, Calò PG, Mocci C, Nicolosi A: Florid papillomatosis of the male nipple. Am J Surg; 2010 Sep;200(3):e39-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Florid papillomatosis of the male nipple.
  • The authors present a case of an adenoma of the nipple in a 61-year-old man who reported a 6-month history of nodularity and itching at his left nipple.
  • Examination revealed a firm, well-defined, vascularized tumor measuring .8 cm that altered the normal anatomy of the nipple.
  • A total excision of the nipple and areola was performed.
  • The histological diagnosis was adenoma of the nipple.
  • [MeSH-major] Adenoma / surgery. Breast Neoplasms, Male / surgery. Nipples / surgery. Papilloma / surgery

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  • [Copyright] 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20409515.001).
  • [ISSN] 1879-1883
  • [Journal-full-title] American journal of surgery
  • [ISO-abbreviation] Am. J. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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