[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 100 of about 127
1. Kitoh T, Yanai H, Matsubara Y, Nakamura Y, Okamoto T, Hirano A, Yoshida T, Okita K: Endoscopic findings potentially predictive of gastric cancer in borderline lesions diagnosed by forceps biopsy. Hepatogastroenterology; 2005 Mar-Apr;52(62):404-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic findings potentially predictive of gastric cancer in borderline lesions diagnosed by forceps biopsy.
  • BACKGROUND/AIMS: When a benign-malignant borderline lesion is diagnosed by the usual small gastric biopsy, there is sometimes difficulty in making a clinical decision.
  • To clarify potentially useful findings to predict the existence of gastric cancer in borderline lesions diagnosed by forceps biopsy, we retrospectively analyzed endoscopic features.
  • METHODOLOGY: We diagnosed 68 consecutive gastric benign-malignant borderline lesions (57 cases) by forceps biopsy and endoscopically resected them.
  • The final diagnosis for 24 lesions (35.3%) was adenocarcinoma (adenocarcinoma group), and for 40 lesions (58.8%) was adenoma (adenoma group).
  • RESULTS: We found six endoscopic findings (distal location, reddish surface color, lack of smoothness, lack of glossiness, focal roughness, and focal redness) having statistically significant relationships with adenocarcinoma at the final pathological diagnosis.
  • In multivariate analysis, focal redness (p<0.01) and lack of glossiness (p<0.05) were found to have a significant relationship to gastric cancer.
  • CONCLUSIONS: Endoscopic findings such as focal redness and lack of glossiness were potentially predictive of gastric cancer in borderline lesions diagnosed by forceps biopsy.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma / pathology. Biopsy / methods. Gastroscopy. Stomach Neoplasms / pathology. Surgical Instruments

  • MedlinePlus Health Information. consumer health - Biopsy.
  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15816445.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Greece
  •  go-up   go-down


2. Lee JH, Cho JY, Choi MG, Kim JS, Choi KD, Lee YC, Jang JY, Chun HJ, Seol SY: Usefulness of autofluorescence imaging for estimating the extent of gastric neoplastic lesions: a prospective multicenter study. Gut Liver; 2008 Dec;2(3):174-9
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Usefulness of autofluorescence imaging for estimating the extent of gastric neoplastic lesions: a prospective multicenter study.
  • BACKGROUND/AIMS: The aim of this study was to determine whether the margin of early to be detected gastric cancer (EGC) and gastric adenoma is easier to be detected with autofluorescence imaging (AFI) than with white-light endoscopy (WLE).
  • METHODS: A total of 102 lesions (48 EGCs and 54 gastric adenomas) found in 98 patients were removed endoscopically or surgically.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Hepatogastroenterology. 2006 Jul-Aug;53(70):643-7 [16995480.001]
  • [Cites] Gastrointest Endosc. 2006 Aug;64(2):176-85 [16860064.001]
  • [Cites] Endoscopy. 1988 Mar;20(2):78-82 [3383798.001]
  • [Cites] Endoscopy. 1994 May;26(4):352-8 [8076567.001]
  • [Cites] Endoscopy. 1993 Sep;25(7):445-50 [8261986.001]
  • [Cites] Endoscopy. 1998 May;30(4):379-86 [9689513.001]
  • [Cites] Endoscopy. 2000 Apr;32(4):281-6 [10774966.001]
  • [Cites] Gut. 2001 Feb;48(2):225-9 [11156645.001]
  • [Cites] Cancer Lett. 2001 Apr 26;165(2):155-9 [11275364.001]
  • [Cites] Gastrointest Endosc. 2001 May;53(6):642-50 [11323596.001]
  • [Cites] Gastrointest Endosc. 2002 Apr;55(4):562-71 [11923776.001]
  • [Cites] Gastrointest Endosc. 2003 Apr;57(4):498-504 [12665759.001]
  • [Cites] Endoscopy. 2003 Aug;35(8):663-8 [12929061.001]
  • [Cites] Respiration. 2003 Jul-Aug;70(4):395-8 [14512675.001]
  • [Cites] IARC Sci Publ. 2004;(157):311-26 [15055304.001]
  • [Cites] Endoscopy. 2004 Jun;36(6):515-21 [15202048.001]
  • [Cites] Gastric Cancer. 2004;7(4):221-32 [15616770.001]
  • [Cites] Gastrointest Endosc. 2005 May;61(6):679-85 [15855971.001]
  • [Cites] J Clin Oncol. 2005 Jul 10;23(20):4490-8 [16002839.001]
  • [Cites] Gastrointest Endosc. 2005 Oct;62(4):521-8 [16185965.001]
  • [Cites] Best Pract Res Clin Gastroenterol. 2005 Dec;19(6):833-56 [16338645.001]
  • [Cites] J Gastroenterol. 2006 Apr;41(4):332-8 [16741612.001]
  • [Cites] Eur J Gastroenterol Hepatol. 2006 Aug;18(8):817-9 [16825896.001]
  • [Cites] Eur J Gastroenterol Hepatol. 2006 Aug;18(8):831-8 [16825898.001]
  • [Cites] Curr Opin Gastroenterol. 2002 Sep;18(5):581-6 [17033337.001]
  • (PMID = 20485643.001).
  • [ISSN] 2005-1212
  • [Journal-full-title] Gut and liver
  • [ISO-abbreviation] Gut Liver
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2871640
  • [Keywords] NOTNLM ; Adenoma / Fluorescence / Gastric cancer / Imaging / Resection
  •  go-up   go-down


3. Chang HJ, Oh SN, Park MY, Rha SE, Choi BG: Fraudulent retouching of digital radiographic images--a potential risk. Clin Radiol; 2010 Dec;65(12):967-73
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • MATERIALS AND METHODS: Ten representative key images were selected of aortic dissection, hepatocellular carcinoma, renal cell carcinoma, colon cancer, liver metastasis, hepatic cyst, gallbladder stones, splenic artery aneurysm, adrenal adenoma, and stomach cancer from abdominal computed tomography (CT) imaging performed in 2008.
  • Radiologists were requested to make a diagnosis for the 10 images, and were then asked to identify possible retouched images.
  • None of the reviewers recognized that some images were retouched during diagnosis.
  • The rate of correct diagnosis was 90% (range 71.7-100%).
  • The time to diagnosis and the time to detection of the retouched images were 15 (14-17) and 6 (5-7) min, respectively.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2010 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 21070899.001).
  • [ISSN] 1365-229X
  • [Journal-full-title] Clinical radiology
  • [ISO-abbreviation] Clin Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  •  go-up   go-down


Advertisement
4. Jang CR, Choi SR, Cho JH, Koo YH, Han SH, Ryu SH, Lee DH, Jang JS, Lee JH, Roh MH, Cho JH: [A case of giant gastric villous tumor with carcinomatous change]. Korean J Gastroenterol; 2005 Jun;45(6):431-5
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of giant gastric villous tumor with carcinomatous change].
  • Villous tumors of the stomach are somewhat rare with approximately 100 cases only reported in the literatures and have tendency to undergo malignant transformation as high as 72%.
  • Thirty percent of them are associated with an independent gastric carcinoma.
  • Gastric villous tumor has certain radiologic characteristics that may permit a preoperative diagnosis and also some distinctive clinicopathologic features which make early diagnosis and proper treatment possible.
  • Esophagogastroduodenoscopy and barium study of upper gastrointestinal tract demonstrated typical, irregular, frond-like surfaced villous tumor occupying nearly whole gastric lumen and located eccentrically along the lesser curvature side.
  • Endoscopic biopsy of the tumor revealed a gastric villous tumor with carcinomatous change.
  • [MeSH-major] Stomach Neoplasms / pathology
  • [MeSH-minor] Adenoma, Villous / diagnostic imaging. Adenoma, Villous / pathology. Carcinoma / diagnostic imaging. Carcinoma / pathology. Humans. Male. Middle Aged. Radiography

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15973078.001).
  • [ISSN] 1598-9992
  • [Journal-full-title] The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
  • [ISO-abbreviation] Korean J Gastroenterol
  • [Language] kor
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  •  go-up   go-down


5. Uemura N: [Gastric adenoma, hyperlastic polyp and fundic gland polyp]. Nihon Rinsho; 2005 Nov;63 Suppl 11:560-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Gastric adenoma, hyperlastic polyp and fundic gland polyp].
  • [MeSH-major] Adenoma. Polyps. Stomach Neoplasms
  • [MeSH-minor] Diagnosis, Differential. Diagnostic Imaging. Gastroscopy. Humans

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16363601.001).
  • [ISSN] 0047-1852
  • [Journal-full-title] Nihon rinsho. Japanese journal of clinical medicine
  • [ISO-abbreviation] Nippon Rinsho
  • [Language] jpn
  • [Publication-type] Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 8
  •  go-up   go-down


6. Hotta K, Oyama T, Akamatsu T, Tomori A, Hasebe O, Nakamura N, Kojima E, Suga T, Miyabayashi H, Ohta H: A comparison of outcomes of endoscopic submucosal dissection (ESD) For early gastric neoplasms between high-volume and low-volume centers: multi-center retrospective questionnaire study conducted by the Nagano ESD Study Group. Intern Med; 2010;49(4):253-9
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A comparison of outcomes of endoscopic submucosal dissection (ESD) For early gastric neoplasms between high-volume and low-volume centers: multi-center retrospective questionnaire study conducted by the Nagano ESD Study Group.
  • OBJECTIVE: Outcomes of endoscopic submucosal dissection (ESD) for early gastric neoplasms at low-volume centers have been unknown, because all previous reports have studied in advanced single centers.
  • Early gastric cancer (EGC) was divided into three categories on the basis of pathological diagnosis-standard indication (SI), expanded indication (EI) and out-of-indication (OI).
  • RESULTS: A total of 703 early gastric neoplasms (586 EGCs, 117 gastric adenomas) were treated with ESD from January to December 2005.
  • CONCLUSION: There were no significant difference in the outcomes of ESD for early gastric neoplasms between high- and low volume centers.
  • [MeSH-major] Endoscopy, Gastrointestinal. Stomach Neoplasms / surgery
  • [MeSH-minor] Adenocarcinoma / surgery. Adenoma / surgery. Dissection. Gastric Mucosa / surgery. Humans. Japan. Postoperative Complications / etiology. Retrospective Studies. Surveys and Questionnaires. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Intern Med. 2010;49(4):251-2 [20154427.001]
  • (PMID = 20154428.001).
  • [ISSN] 1349-7235
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study
  • [Publication-country] Japan
  •  go-up   go-down


7. Fujishiro M, Yahagi N, Nakamura M, Kakushima N, Kodashima S, Ono S, Kobayashi K, Hashimoto T, Yamamichi N, Tateishi A, Shimizu Y, Oka M, Ogura K, Kawabe T, Ichinose M, Omata M: Endoscopic submucosal dissection for rectal epithelial neoplasia. Endoscopy; 2006 May;38(5):493-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND AND STUDY AIMS: The technique of endoscopic submucosal dissection (ESD) has recently been developed for en-bloc resection of gastric tumors.
  • PATIENTS AND METHODS: Thirty-five consecutive patients with rectal neoplasia who had a preoperative diagnosis of large intraepithelial neoplasias with submucosal fibrosis or located on the rectal folds were enrolled.
  • ESD was carried out with the same technique previously described for the stomach, with some modifications.
  • The exception was a patient in whom a multiple-piece resection was required; the recurrent (residual) tumor, found 2 months after ESD, was a small adenoma that was again treated endoscopically.

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16767585.001).
  • [ISSN] 0013-726X
  • [Journal-full-title] Endoscopy
  • [ISO-abbreviation] Endoscopy
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


8. Kato M, Kaise M, Yonezawa J, Yoshida Y, Tajiri H: Autofluorescence endoscopy versus conventional white light endoscopy for the detection of superficial gastric neoplasia: a prospective comparative study. Endoscopy; 2007 Nov;39(11):937-41
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Autofluorescence endoscopy versus conventional white light endoscopy for the detection of superficial gastric neoplasia: a prospective comparative study.
  • BACKGROUND AND STUDY AIMS: Preliminary studies have suggested autofluorescence endoscopy (AFE) to be accurate in the diagnosis of gastric tumors.
  • Our prospective blinded study systematically compared AFE with white light endoscopy (WLE) for the detection of superficial gastric neoplasia.
  • PATIENTS AND METHODS: An enriched population included 33 patients with superficial gastric neoplasia referred for endoscopic submucosal dissection (ESD), and 18 control patients undergoing follow-up endoscopy after curative ESD.
  • RESULTS: 39 gastric neoplasias were histologically confirmed and 52 non-neoplastic lesions were found to be either WLE- and/or AFE-positive.
  • CONCLUSIONS: Although one quarter of elevated gastric neoplasias were detected only by AFE, its specificity is poor; therefore its clinical value is limited.
  • [MeSH-major] Gastroscopes. Gastroscopy / methods. Stomach Neoplasms / pathology
  • [MeSH-minor] Adenoma / pathology. Adenoma / surgery. Aged. Biopsy, Needle. Carcinoma / pathology. Carcinoma / surgery. Case-Control Studies. False Negative Reactions. False Positive Reactions. Female. Fluorescence. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Staging. Probability. Prospective Studies. Sensitivity and Specificity

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Endoscopy. 2007 Nov;39(11):1021-2 [18008209.001]
  • (PMID = 18008201.001).
  • [ISSN] 1438-8812
  • [Journal-full-title] Endoscopy
  • [ISO-abbreviation] Endoscopy
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


9. Jeong HK, Park CH, Jun CH, Lee GH, Kim HI, Kim HS, Choi SK, Rew JS: A prospective randomized trial of either famotidine or pantoprazole for the prevention of bleeding after endoscopic submucosal dissection. J Korean Med Sci; 2007 Dec;22(6):1055-9
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In a prospective trial, patients undergoing ESD due to gastric adenoma or adenocarcinoma were randomly assigned to pantoprazole or famotidine.
  • [MeSH-major] 2-Pyridinylmethylsulfinylbenzimidazoles / therapeutic use. Anti-Ulcer Agents / therapeutic use. Famotidine / therapeutic use. Gastric Mucosa / surgery. Gastrointestinal Hemorrhage / prevention & control. Gastroscopy. Postoperative Hemorrhage / prevention & control. Stomach Neoplasms / surgery

  • MedlinePlus Health Information. consumer health - Gastrointestinal Bleeding.
  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • Hazardous Substances Data Bank. PANTOPRAZOLE .
  • Hazardous Substances Data Bank. FAMOTIDINE .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] N Engl J Med. 2000 Aug 3;343(5):310-6 [10922420.001]
  • [Cites] Gastrointest Endosc. 2006 Dec;64(6):877-83 [17140890.001]
  • [Cites] Gastrointest Endosc. 2002 Mar;55(3):390-6 [11868015.001]
  • [Cites] Gastrointest Endosc. 2002 Apr;55(4):576-81 [11923778.001]
  • [Cites] Gastrointest Endosc. 2002 Oct;56(4):507-12 [12297765.001]
  • [Cites] Gastrointest Endosc. 2003 Apr;57(4):567-79 [12665775.001]
  • [Cites] Gastrointest Endosc. 2003 May;57(6):687-90 [12709698.001]
  • [Cites] Endoscopy. 2003 Jul;35(7):611-2 [12822098.001]
  • [Cites] Endoscopy. 2003 Aug;35(8):690-4 [12929067.001]
  • [Cites] Am J Gastroenterol. 2003 Dec;98(12):2635-41 [14687809.001]
  • [Cites] Endoscopy. 2004 Sep;36(9):788-801 [15326574.001]
  • [Cites] Endoscopy. 2004 Sep;36(9):808-10 [15326576.001]
  • [Cites] Gastroenterology. 1978 Jan;74(1):38-43 [21830.001]
  • [Cites] Scand J Gastroenterol Suppl. 1987;134:55-60 [2889260.001]
  • [Cites] Arch Intern Med. 1998 Jan 12;158(1):54-8 [9437379.001]
  • [Cites] Endoscopy. 1999 Jan;31(1):47-55 [10082409.001]
  • [Cites] Gastrointest Endosc. 1999 Aug;50(2):251-6 [10425422.001]
  • [Cites] Aliment Pharmacol Ther. 1999 Aug;13 Suppl 3:18-26 [10491725.001]
  • [Cites] Intern Med. 2004 Dec;43(12):1120-5 [15645644.001]
  • [Cites] Aliment Pharmacol Ther. 2005 Jun;21 Suppl 2:111-5 [15943857.001]
  • [Cites] Dig Dis Sci. 2006 Jan;51(1):123-31 [16416224.001]
  • [Cites] Gastrointest Endosc. 2006 Feb;63(2):243-9 [16427929.001]
  • [Cites] World J Gastroenterol. 2005 Dec 14;11(46):7335-9 [16437638.001]
  • [Cites] Aliment Pharmacol Ther. 2006 Sep 1;24(5):837-43 [16918888.001]
  • [Cites] Endoscopy. 2001 Mar;33(3):221-6 [11293753.001]
  • (PMID = 18162722.001).
  • [ISSN] 1011-8934
  • [Journal-full-title] Journal of Korean medical science
  • [ISO-abbreviation] J. Korean Med. Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial
  • [Publication-country] Korea (South)
  • [Chemical-registry-number] 0 / 2-Pyridinylmethylsulfinylbenzimidazoles; 0 / Anti-Ulcer Agents; 5QZO15J2Z8 / Famotidine; D8TST4O562 / pantoprazole
  • [Other-IDs] NLM/ PMC2694634
  •  go-up   go-down


10. Karam SM, Tomasetto C, Rio MC: Amplification and invasiveness of epithelial progenitors during gastric carcinogenesis in trefoil factor 1 knockout mice. Cell Prolif; 2008 Dec;41(6):923-935
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Amplification and invasiveness of epithelial progenitors during gastric carcinogenesis in trefoil factor 1 knockout mice.
  • OBJECTIVE: It is not known whether or not epithelial progenitors of the pyloric antrum are involved in gastric carcinogenesis.
  • This study was designed to examine the changes that occur in pyloric antral mucous cell lineages and their progenitors during development of gastric adenoma and carcinoma in trefoil factor 1 (TFF1) knockout mice.
  • CONCLUSION: This study shows that the progenitors of pit and gland mucous cells contribute to gastric carcinogenesis in the pyloric antrum of TFF1 knockout mice, strongly supporting the concept of stem cell origin of cancer.
  • [MeSH-major] Epithelial Cells / pathology. Peptides / deficiency. Stem Cells / pathology. Stomach Neoplasms / pathology
  • [MeSH-minor] Aging / pathology. Animals. Cell Differentiation. Cell Division. Cell Lineage. Cell Proliferation. Gastric Mucosa / pathology. Gastric Mucosa / ultrastructure. Lectins / metabolism. Mice. Mice, Inbred C57BL. Mice, Knockout. Neoplasm Invasiveness. Pyloric Antrum / pathology. Pyloric Antrum / ultrastructure. Pylorus / pathology. Pylorus / ultrastructure. Trefoil Factor-1

  • MedlinePlus Health Information. consumer health - Stem Cells.
  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19040570.001).
  • [ISSN] 1365-2184
  • [Journal-full-title] Cell proliferation
  • [ISO-abbreviation] Cell Prolif.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Lectins; 0 / Peptides; 0 / Tff1 protein, mouse; 0 / Trefoil Factor-1
  •  go-up   go-down


11. Kurland J, DuBois S, Behling C, Savides T: Severe upper-GI bleed caused by gastritis cystica profunda. Gastrointest Endosc; 2006 Apr;63(4):716-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenoma / complications. Gastritis / complications. Gastrointestinal Hemorrhage / etiology. Stomach Neoplasms / complications
  • [MeSH-minor] Aged. Biopsy. Diagnosis, Differential. Gastrectomy. Humans. Male

  • MedlinePlus Health Information. consumer health - Gastrointestinal Bleeding.
  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16564886.001).
  • [ISSN] 0016-5107
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


12. Kushima R, Vieth M, Borchard F, Stolte M, Mukaisho K, Hattori T: Gastric-type well-differentiated adenocarcinoma and pyloric gland adenoma of the stomach. Gastric Cancer; 2006;9(3):177-84
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gastric-type well-differentiated adenocarcinoma and pyloric gland adenoma of the stomach.
  • Since 1985, when gastric-type well-differentiated adenocarcinomas were demonstrated in hyperplastic polyps of the stomach, we have studied phenotypic expression in gastrointestinal epithelial lesions.
  • The disease entity of gastric-type well-differentiated adenocarcinoma has recently been accepted, especially in Japan and Europe.
  • Even under these circumstances, the term "gastric adenoma" usually means flat adenoma of the intestinal type.
  • Gastric-type adenomas have been regarded as exceptional until recently.
  • Although gastric-type adenomas could theoretically be classified into foveolar type and pyloric-gland type, foveolar-type adenoma is, in practice, difficult to distinguish from gastric-foveolar-type adenocarcinoma.
  • In 2003, we first reported systematic clinicopathological analyses of pyloric gland adenoma, demonstrating its unstable and precancerous nature.
  • In this article, we review and discuss the clinicopathological and molecular pathological aspects of gastric-type well-differentiated adenocarcinomas and pyloric gland adenomas, mainly based on our published and unpublished data.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenoma / diagnosis. Gastric Mucosa / pathology. Stomach Neoplasms / diagnosis
  • [MeSH-minor] Chromosome Aberrations. Humans. Molecular Diagnostic Techniques. Nucleic Acid Hybridization / methods. Stomach / cytology. Stomach / pathology

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Oncology. 2001;61(1):1-9 [11474241.001]
  • [Cites] Hum Pathol. 2002 Jan;33(1):80-6 [11823976.001]
  • [Cites] Pathologe. 2001 Jan;22(1):44-55 [11225445.001]
  • [Cites] Mod Pathol. 2003 Aug;16(8):786-95 [12920223.001]
  • [Cites] Int J Cancer. 2001 Oct 15;94(2):166-70 [11668493.001]
  • [Cites] Pathol Int. 2004 Nov;54(11):854-60 [15533229.001]
  • [Cites] Nihon Shokakibyo Gakkai Zasshi. 1995 Apr;92(4):761-8 [7739127.001]
  • [Cites] Am J Pathol. 1999 Jan;154(1):77-82 [9916921.001]
  • [Cites] Am J Surg Pathol. 1995;19 Suppl 1:S37-43 [7762738.001]
  • [Cites] Int J Cancer. 2002 Apr 10;98(5):737-40 [11920644.001]
  • [Cites] Acta Pathol Microbiol Scand. 1965;64:31-49 [14320675.001]
  • [Cites] J Clin Pathol. 1985 Jun;38(6):622-30 [4008664.001]
  • [Cites] J Biol Chem. 2001 May 25;276(21):18327-36 [11278439.001]
  • [Cites] Virchows Arch. 2005 May;446(5):542-5 [15838648.001]
  • [Cites] Oncol Rep. 2001 Jan-Feb;8(1):17-26 [11115563.001]
  • [Cites] Virchows Arch. 2003 Apr;442(4):317-21 [12715167.001]
  • [Cites] Virchows Arch. 2002 Feb;440(2):205-8 [11964052.001]
  • [Cites] Virchows Arch. 2005 May;446(5):537-41 [15838649.001]
  • [Cites] Acta Pathol Jpn. 1982;32 Suppl 2:329-47 [6765003.001]
  • [Cites] Virchows Arch. 1999 Oct;435(4):452-7 [10526011.001]
  • [Cites] Cancer Res. 1999 Mar 1;59(5):1003-7 [10070955.001]
  • [Cites] Gan. 1968 Jun;59(3):251-8 [5726267.001]
  • [Cites] Am J Surg Pathol. 2002 Oct;26(10):1276-85 [12360042.001]
  • [Cites] Pathol Int. 1996 Nov;46(11):908-17 [8970203.001]
  • [Cites] J Cancer Res Clin Oncol. 1993;120(1-2):103-11 [7903667.001]
  • [Cites] Verh Dtsch Ges Pathol. 2000;84:50-61 [11217449.001]
  • [Cites] Pathol Int. 2004 May;54(5):311-21 [15086835.001]
  • [Cites] Acta Pathol Jpn. 1990 Jul;40(7):494-504 [2220396.001]
  • [Cites] Crit Rev Oncol Hematol. 1994 Dec;17(3):153-80 [7865137.001]
  • [Cites] J Natl Cancer Inst. 1991 May 1;83(9):640-3 [2023282.001]
  • [Cites] Pathol Res Pract. 1996 Sep;192(9):963-9; discussion 970-1 [8950764.001]
  • (PMID = 16952035.001).
  • [ISSN] 1436-3291
  • [Journal-full-title] Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
  • [ISO-abbreviation] Gastric Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 42
  •  go-up   go-down


13. Matsuda A, Kato S, Furuya M, Shimizu Y, Okino T, Sasaki J, Tajiri T: Multiple early gastric cancer with duodenal invasion. World J Surg Oncol; 2007;5:125
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multiple early gastric cancer with duodenal invasion.
  • BACKGROUND: Early gastric cancers with duodenal invasion are rare, and no previous case of multiple early gastric cancer, one invading the duodenal bulb, has been reported.
  • Biopsy revealed a tubular adenoma for the antrum lesion and a well-differentiated tubular adenocarcinoma for the prepyloric lesion.
  • CONCLUSION: Here, we present an unusual case of multiple early gastric cancer, one of which invaded the duodenum with relative wide mucosal spreading.
  • This case illustrates that even early stage cancers located in the gastric antrum, particularly in the prepyloric area can invade the duodenum directly.
  • [MeSH-major] Adenocarcinoma, Papillary / secondary. Duodenal Neoplasms / secondary. Neoplasm Invasiveness / pathology. Neoplasms, Multiple Primary / pathology. Stomach Neoplasms / pathology
  • [MeSH-minor] Abdominal Pain / diagnosis. Abdominal Pain / etiology. Aged. Biopsy, Needle. Female. Follow-Up Studies. Gastrectomy / methods. Humans. Immunohistochemistry. Laparotomy / methods. Neoplasm Staging. Risk Assessment. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Intestinal Cancer.
  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Surgery. 2001 Jun;129(6):714-9 [11391370.001]
  • [Cites] Shujutsu. 1966 Nov;20(11):986-96 [5981650.001]
  • [Cites] Cancer. 1991 Jul 15;68(2):380-4 [2070336.001]
  • [Cites] Am Surg. 2005 Apr;71(4):366-8 [15943416.001]
  • [Cites] Kurume Med J. 1996;43(3):189-98 [8942138.001]
  • [Cites] Gastroenterology. 1957 Jun;32(6):1095-103 [13438166.001]
  • [Cites] J Surg Oncol. 1995 Aug;59(4):215-9 [7630166.001]
  • (PMID = 17971200.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2173897
  •  go-up   go-down


14. Imaeda H, Hosoe N, Kashiwagi K, Ida Y, Saito Y, Suzuki H, Aiura K, Ogata H, Kumai K, Hibi T: Autofluorescence videoendoscopy system using the SAFE-3000 for assessing superficial gastric neoplasia. J Gastroenterol Hepatol; 2010 Apr;25(4):706-11
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Autofluorescence videoendoscopy system using the SAFE-3000 for assessing superficial gastric neoplasia.
  • BACKGROUND: Autofluorescence (AF) videoendoscopy has an advantage over ordinary videoendoscopy in the diagnosis of gastric neoplasias, and the aim of the present study was to evaluate the effectiveness of using the SAFE-3000 videoendoscopy system to diagnose superficial gastric neoplasias.
  • METHODS: Ordinary videoendoscopy, AF videoendoscopy, and chromoendoscopy (CE) were used to diagnose the tumor existence and extent in 14 patients with gastric adenoma, 40 patients with intestinal-type early gastric cancer (EGC) (10 protruded, and 30 depressed), and nine patients with diffuse-type EGC.
  • RESULTS: For gastric adenomas the diagnostic accuracy between the AF images and white light (WL) images did not differ significantly, and for protruded intestinal-type EGCs and diffuse-type EGCs the diagnostic accuracy did not differ significantly between any of the types of images.
  • The detection rate of pink or orange color in AF images was significantly higher for protruded intestinal-type EGCs than gastric adenomas (P = 0.005), depressed intestinal-type EGCs (P < 0.001), and diffuse-type EGCs (P = 0.027).
  • CONCLUSIONS: Autofluorescence videoendoscopy using the SAFE-3000 system for gastric neoplasias might be useful for diagnosing depressed intestinal-type early gastric cancers.
  • The detection of orange or pink color in AF images may be efficacious in discriminating protruded intestinal-type early gastric cancers from gastric adenomas.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma / pathology. Endoscopes, Gastrointestinal. Endoscopy, Gastrointestinal. Stomach Neoplasms / pathology. Video Recording
  • [MeSH-minor] Aged. Cell Differentiation. Diagnosis, Differential. Equipment Design. Female. Fluorescence. Humans. Male. Middle Aged. Neoplasm Staging. Predictive Value of Tests

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20492326.001).
  • [ISSN] 1440-1746
  • [Journal-full-title] Journal of gastroenterology and hepatology
  • [ISO-abbreviation] J. Gastroenterol. Hepatol.
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Australia
  •  go-up   go-down


15. Kushima R, Vieth M: [Tubular adenoma of the stomach with special reference to the Japanese criteria and pyloric gland adenoma]. Pathologe; 2010 May;31(3):177-81
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Tubular adenoma of the stomach with special reference to the Japanese criteria and pyloric gland adenoma].
  • [Transliterated title] Das tubuläre Magenadenom. Mit Darstellung der Japanischen Kriterien unter Berücksichtigung des "pyloric gland adenoma"
  • The term gastric adenoma usually refers to a flat adenoma of the intestinal type.
  • Adenomas of the gastric type, so-called pyloric gland adenomas (PGA), which was first characterized by German and Japanese pathologists in 1990, have been regarded as exceptional until recently.
  • In this article we introduce the Japanese criteria of the gastric adenoma and review and discuss the clinical pathological and molecular aspects of PGAs.
  • [MeSH-major] Adenoma / pathology. Gastric Mucosa / pathology. Intestinal Neoplasms / genetics. Intestinal Neoplasms / pathology. Stomach Neoplasms / genetics. Stomach Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Mod Pathol. 2003 Aug;16(8):786-95 [12920223.001]
  • [Cites] Int J Cancer. 2001 Oct 15;94(2):166-70 [11668493.001]
  • [Cites] Gut. 2000 Aug;47(2):251-5 [10896917.001]
  • [Cites] Virchows Arch. 2005 May;446(5):542-5 [15838648.001]
  • [Cites] Virchows Arch. 2003 Apr;442(4):317-21 [12715167.001]
  • [Cites] Virchows Arch. 2002 Feb;440(2):205-8 [11964052.001]
  • [Cites] Virchows Arch. 2005 May;446(5):537-41 [15838649.001]
  • [Cites] Virchows Arch. 1999 Oct;435(4):452-7 [10526011.001]
  • [Cites] Am J Surg Pathol. 2002 Oct;26(10):1276-85 [12360042.001]
  • [Cites] Pathol Int. 1996 Nov;46(11):908-17 [8970203.001]
  • [Cites] Pathol Res Pract. 1996 Sep;192(9):963-9; discussion 970-1 [8950764.001]
  • [Cites] Gastric Cancer. 2006;9(3):177-84 [16952035.001]
  • (PMID = 20349063.001).
  • [ISSN] 1432-1963
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


16. Futagami S, Hiratsuka T, Shindo T, Horie A, Hamamoto T, Suzuki K, Kusunoki M, Miyake K, Gudis K, Crowe SE, Tsukui T, Sakamoto C: Expression of apurinic/apyrimidinic endonuclease-1 (APE-1) in H. pylori-associated gastritis, gastric adenoma, and gastric cancer. Helicobacter; 2008 Jun;13(3):209-18
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of apurinic/apyrimidinic endonuclease-1 (APE-1) in H. pylori-associated gastritis, gastric adenoma, and gastric cancer.
  • However, little is known about the localization of APE-1 in Helicobacter pylori-infected gastric mucosa or its role in the development of gastric cancer.
  • To investigate the role of APE-1 in the development of gastric cancer, we examined APE-1 expression and localization in cultured cells and gastric biopsies from patients with H. pylori-infected gastritis or gastric adenoma, and from surgically resected gastric cancer.
  • METHODS: APE-1 mRNA and protein expression were determined in H. pylori (CagA+) water-extract protein (HPWEP)-stimulated MKN-28 cells, gastric adenocarcinoma cell-line (AGS) cells, and human peripheral macrophages by real-time polymerase chain reaction and Western blot analysis.
  • Localization of APE-1 and IkappaBalpha phosphorylation in gastric adenoma and gastric cancer tissues were evaluated by single- and double-label immunohistochemistry.
  • Eradication therapy significantly reduced both APE-1 and 8-OHdG expression levels in the gastric mucosa.
  • APE-1 expression was mainly localized in epithelial cells within gastric adenoma and in mesenchymal cells of gastric cancer tissues.
  • APE-1 expression in gastric cancer tissues was significantly reduced compared to that in H. pylori-infected gastric adenoma, while 8-OHdG index and IkappaBalpha phosphorylation levels did not differ between these two neoplastic tissue types.
  • Co-localization of APE-1 and IkappaBalpha phosphorylation was observed not in gastric cancer cells but in gastric adenoma cells.
  • CONCLUSION: H. pylori infection is associated with increased APE-1 expression in human cell lines and in gastric tissues from subjects with gastritis and gastric adenomas.
  • The observed distinct expression patterns of APE-1 and 8-OHdG in gastric adenoma and gastric cancer tissues may provide insight into the progression of these conditions and warrants further investigation.
  • [MeSH-major] DNA-(Apurinic or Apyrimidinic Site) Lyase / metabolism. Gastritis / enzymology. Gastritis / microbiology. Helicobacter Infections / enzymology. Helicobacter pylori. Stomach Neoplasms / enzymology. Stomach Neoplasms / microbiology
  • [MeSH-minor] Adenoma / enzymology. Adenoma / genetics. Adenoma / microbiology. Adult. Aged. Cells, Cultured. Female. Gastric Mucosa / metabolism. Gastric Mucosa / microbiology. Humans. Male. Middle Aged. RNA, Messenger / metabolism

  • MedlinePlus Health Information. consumer health - Helicobacter Pylori Infections.
  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18466396.001).
  • [ISSN] 1523-5378
  • [Journal-full-title] Helicobacter
  • [ISO-abbreviation] Helicobacter
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / R01 DK061769
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / RNA, Messenger; EC 4.2.99.18 / APEX1 protein, human; EC 4.2.99.18 / DNA-(Apurinic or Apyrimidinic Site) Lyase
  •  go-up   go-down


17. Tanaka K, Toyoda H, Kadowaki S, Kosaka R, Shiraishi T, Imoto I, Shiku H, Adachi Y: Features of early gastric cancer and gastric adenoma by enhanced-magnification endoscopy. J Gastroenterol; 2006 Apr;41(4):332-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Features of early gastric cancer and gastric adenoma by enhanced-magnification endoscopy.
  • BACKGROUND: Changes to the mucosal surface of early gastric carcinomas and gastric adenomas as viewed by enhanced-magnification endoscopy with acetic acid have not been investigated thoroughly.
  • Using this technology, we investigated the appearance of the gastric surface patterns of neoplastic and surrounding nonneoplastic mucosa.
  • METHODS: Forty-seven consecutive patients with early gastric carcinomas or gastric adenomas underwent enhanced-magnification endoscopy following 1.5% acetic acid instillation.
  • RESULTS: Surface patterns of gastric tumors and the surrounding mucosa were classified into five types: type I, small round pits of uniform size and shape; type II, slit-like pits; type III, gyrus and villous patterns; type IV, irregular arrangements and sizes of pattern types I, II and III; type V, destructive patterns of types I, II and III.
  • CONCLUSIONS: Enhanced-magnification endoscopy may be useful for identifying gastric tumors and determining the extent of horizontal spread, especially in tumors of the depressed type.
  • [MeSH-major] Adenoma / pathology. Carcinoma / pathology. Endoscopy, Gastrointestinal / methods. Image Enhancement. Stomach Neoplasms / pathology
  • [MeSH-minor] Biopsy. Diagnosis, Differential. Follow-Up Studies. Humans. Neoplasm Staging. Prospective Studies. Video Recording

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] J Gastroenterol. 2006 Apr;41(4):397-8 [16741625.001]
  • [Cites] Endoscopy. 2004 Feb;36(2):165-9 [14765314.001]
  • [Cites] Gastrointest Endosc. 2004 Jan;59(1):15-21 [14722541.001]
  • [Cites] Am J Surg Pathol. 1995;19 Suppl 1:S37-43 [7762738.001]
  • [Cites] Gastrointest Endosc. 2001 May;53(6):559-65 [11323579.001]
  • [Cites] Gastrointest Endosc. 2003 Apr;57(4):498-504 [12665759.001]
  • [Cites] Gastrointest Endosc. 2002 Aug;56(2):279-84 [12145613.001]
  • [Cites] Endoscopy. 2003 May;35(5):437-45 [12701018.001]
  • [Cites] Endoscopy. 2002 Oct;34(10):772-7 [12244497.001]
  • [Cites] Endoscopy. 1978 Nov;10(4):269-74 [738222.001]
  • [Cites] Endoscopy. 2004 Dec;36(12):1080-4 [15578298.001]
  • [Cites] Aliment Pharmacol Ther. 2002 Mar;16 Suppl 1:3-15 [11849122.001]
  • (PMID = 16741612.001).
  • [ISSN] 0944-1174
  • [Journal-full-title] Journal of gastroenterology
  • [ISO-abbreviation] J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


18. Kim KM: [Is streoscopic finding valuable for the pathologic diagnosis of endoscopic submucosal dissection specimen?]. Korean J Gastroenterol; 2010 Nov;56(5):334-5
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Is streoscopic finding valuable for the pathologic diagnosis of endoscopic submucosal dissection specimen?].
  • [MeSH-major] Dissection / methods. Gastric Mucosa / pathology. Gastroscopy / methods
  • [MeSH-minor] Adenoma / pathology. Humans. Stomach Neoplasms / pathology. Stomach Neoplasms / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentOn] Korean J Gastroenterol. 2010 Nov;56(5):293-8 [21099236.001]
  • (PMID = 21099243.001).
  • [ISSN] 1598-9992
  • [Journal-full-title] The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
  • [ISO-abbreviation] Korean J Gastroenterol
  • [Language] kor
  • [Publication-type] Comment; Editorial
  • [Publication-country] Korea (South)
  •  go-up   go-down


19. Minematsu H, Saito Y, Kakinoki R, Andoh A, Kushima R, Fujiyama Y: Evaluation of mucin expression patterns in gastric borderline (group III) lesions. J Gastroenterol; 2006 Jun;41(6):547-53
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Evaluation of mucin expression patterns in gastric borderline (group III) lesions.
  • BACKGROUND: Recommendations for diagnosis and treatment of gastric borderline (group III) lesions remain controversial.
  • METHODS: Sixty-three gastric lesions were histopathologically identified as belonging to group III on the basis of an endoscopic forceps biopsy.
  • All of the patients underwent endoscopic resection, and the lesions were classified into group A (final diagnosis, adenocarcinoma) or group B (final diagnosis, adenoma).
  • RESULTS: The proportion of complete gastric (positive for MUC5AC and MUC6) plus gastric-predominant phenotypes was significantly higher in group A (58.0%) than in group B (18.7%) lesions (P < 0.05).
  • CONCLUSIONS: Immunostaining of forceps biopsy samples for the mucin phenotype may be helpful for diagnosing gastric borderline (group III) lesions.
  • [MeSH-major] Mucins / biosynthesis. Stomach Neoplasms / classification. Stomach Neoplasms / metabolism

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Glycoconj J. 1996 Oct;13(5):693-707 [8909996.001]
  • [Cites] Clin Gastroenterol Hepatol. 2005 Jul;3(7 Suppl 1):S74-6 [16013004.001]
  • [Cites] Int J Cancer. 2001 Oct 15;94(2):166-70 [11668493.001]
  • [Cites] Gut. 2000 Aug;47(2):251-5 [10896917.001]
  • [Cites] Anticancer Res. 2005 Sep-Oct;25(5):3513-6 [16101171.001]
  • [Cites] Virchows Arch. 2003 Apr;442(4):317-21 [12715167.001]
  • [Cites] Oncology. 2001;61(3):212-20 [11574777.001]
  • [Cites] Cancer. 1994 Dec 1;74(11):2896-907 [7954254.001]
  • [Cites] Cancer Res. 1999 Mar 1;59(5):1003-7 [10070955.001]
  • [Cites] Virchows Arch. 2002 Mar;440(3):304-10 [11889602.001]
  • [Cites] J Cancer Res Clin Oncol. 1998;124(9):497-502 [9808424.001]
  • [Cites] Endoscopy. 1993 May;25(4):265-8 [8330543.001]
  • [Cites] Cancer. 2001 Sep 15;92(6):1427-34 [11745219.001]
  • [Cites] Pathol Int. 2004 May;54(5):311-21 [15086835.001]
  • [Cites] Gut. 1995 Jun;36(6):848-52 [7615272.001]
  • [Cites] Eur J Cancer. 1996 Feb;32A(2):215-20 [8664030.001]
  • [Cites] Chin J Dig Dis. 2005;6(3):119-21 [16045601.001]
  • [Cites] Hum Pathol. 1999 Jul;30(7):826-32 [10414502.001]
  • (PMID = 16868802.001).
  • [ISSN] 0944-1174
  • [Journal-full-title] Journal of gastroenterology
  • [ISO-abbreviation] J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Mucins
  •  go-up   go-down


20. Haziri A, Juniku-Shkololli A, Gashi Z, Berisha D, Haziri A: Helicobacter pylori infection and precancerous lesions of the stomach. Med Arh; 2010;64(4):248-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Helicobacter pylori infection and precancerous lesions of the stomach.
  • INTRODUCTION: Chronic atrophic gastritis, intestinal metaplasia, hereditary non-polyposos colon cancer, gastric dysplasia, gastric adenoma, Barrett esophagitis and familiar adenomatous polyposis are confirmed precancerous lesions of the stomach.
  • -in patients with intestinal metaplasia: 71.7%, with gastric dysplasia: 71.4%, with gastric ulcer: 68.4%, with atrophic gastritis: 66.0% and with Barrett esophagitis: 55.0%.
  • CONCLUSIONS: Precancerous lesions of stomach are associated with high percentage of Helicobacter pylori infection.
  • [MeSH-major] Helicobacter Infections / complications. Helicobacter pylori. Precancerous Conditions / microbiology. Stomach Neoplasms / microbiology

  • MedlinePlus Health Information. consumer health - Helicobacter Pylori Infections.
  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21246927.001).
  • [Journal-full-title] Medicinski arhiv
  • [ISO-abbreviation] Med Arh
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Bosnia and Herzegovina
  •  go-up   go-down


21. Saito S, Hosoya Y, Togashi K, Kurashina K, Haruta H, Hyodo M, Koinuma K, Horie H, Yasuda Y, Nagai H: Prevalence of synchronous colorectal neoplasms detected by colonoscopy in patients with gastric cancer. Surg Today; 2008;38(1):20-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Prevalence of synchronous colorectal neoplasms detected by colonoscopy in patients with gastric cancer.
  • PURPOSE: Our purpose was to study the characteristics of colorectal neoplasms in patients with gastric cancer (GC).
  • Synchronous colorectal adenoma and cancer were detected in 182 (39%) and 18 (4%) patients, respectively.
  • [MeSH-major] Colonoscopy / methods. Colorectal Neoplasms / epidemiology. Neoplasms, Multiple Primary / epidemiology. Stomach Neoplasms / epidemiology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Japan / epidemiology. Male. Middle Aged. Neoplasm Staging / methods. Prevalence. Retrospective Studies. Risk Factors


22. Wu CP, Jiang JT, Tan M, Zhu YB, Ji M, Xu KF, Zhao JM, Zhang GB, Zhang XG: Relationship between co-stimulatory molecule B7-H3 expression and gastric carcinoma histology and prognosis. World J Gastroenterol; 2006 Jan 21;12(3):457-9
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Relationship between co-stimulatory molecule B7-H3 expression and gastric carcinoma histology and prognosis.
  • AIM: To investigate the expression of co-stimulatory molecule B7-H3 in gastric carcinoma and adenoma tissue as well as normal gastric tissue and to explore the relationship between B7-H3 expression and pathological features and prognosis of gastric carcinoma.
  • METHODS: B7-H3 expression was detected in 102 samples of human gastric carcinoma and 10 samples of gastric adenoma and 10 samples of normal gastric tissue by immunohistochemical assay.
  • Correlation between the expression of B7-H3 and the patients' age, sex, gastric carcinoma locus, tumor size, tissue type, tumor infiltration depth, differentiation degree, lymph node metastasis, and survival time was analyzed.
  • RESULTS: B7-H3 was expressed in all gastric adenoma samples and in 58.8% samples of gastric carcinoma.
  • B7-H3 expression in gastric carcinoma samples was not related with the patients' age, sex, lymph node metastasis, and tumor size (P>0.05), but with the survival time, infiltration depth of tumor and tissue type.
  • CONCLUSION: Detection of B7-H3 expression in gastric carcinoma tissue is beneficial to the judgment of the prognosis of gastric carcinoma patients and the choice of treatment.
  • [MeSH-major] Adenoma / metabolism. Carcinoma / metabolism. Stomach Neoplasms / metabolism
  • [MeSH-minor] Antigens, CD. Antigens, CD80 / metabolism. B7 Antigens. Gastric Mucosa / cytology. Gastric Mucosa / metabolism. Humans. Immunohistochemistry. Prognosis. Receptors, Immunologic. Retrospective Studies. Survival Rate

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Nat Med. 1999 Dec;5(12):1365-9 [10581077.001]
  • [Cites] J Exp Med. 2001 Apr 2;193(7):839-46 [11283156.001]
  • [Cites] Nat Rev Immunol. 2002 Apr;2(4):227-38 [12001994.001]
  • [Cites] J Immunol. 2004 Feb 15;172(4):2352-9 [14764704.001]
  • [Cites] Genomics. 2003 Sep;82(3):365-77 [12906861.001]
  • [Cites] Gene Ther. 2003 Sep;10(20):1728-34 [12939639.001]
  • [Cites] Nat Immunol. 2003 Sep;4(9):899-906 [12925852.001]
  • [Cites] Protein Expr Purif. 2003 Jun;29(2):148-55 [12767803.001]
  • (PMID = 16489649.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD80; 0 / B7 Antigens; 0 / CD276 protein, human; 0 / Receptors, Immunologic
  • [Other-IDs] NLM/ PMC4066068
  •  go-up   go-down


23. Imaeda H, Hosoe N, Ida Y, Kashiwagi K, Morohoshi Y, Suganuma K, Nagakubo S, Komatsu K, Suzuki H, Saito Y, Aiura K, Ogata H, Iwao Y, Kumai K, Kitagawa Y, Hibi T: Novel technique of endoscopic submucosal dissection using an external grasping forceps for superficial gastric neoplasia. Dig Endosc; 2009 Apr;21(2):122-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Novel technique of endoscopic submucosal dissection using an external grasping forceps for superficial gastric neoplasia.
  • Endoscopic submucosal dissection (ESD) for early stage gastric cancer (EGC) has improved the success rate of en bloc resection but results in perforation more often than does endoscopic mucosal resection.
  • A total of 265 lesions with EGC or gastric adenoma were enrolled in this study.
  • Sixteen lesions were located in the upper third portion of the stomach, 114 in the middle third portion, and 135 in the lower third portion.
  • It was difficult to carry out this procedure when the lesions were located in the cardia, lesser curvature, or posterior wall of the upper third of the gastric body.
  • The endoscopic submucosal dissection using an external grasping forceps for superficial gastric neoplasia is efficacious and safe.
  • [MeSH-major] Gastric Mucosa / surgery. Gastroscopy / methods. Stomach Neoplasms / surgery

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19691787.001).
  • [ISSN] 1443-1661
  • [Journal-full-title] Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society
  • [ISO-abbreviation] Dig Endosc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
  •  go-up   go-down


24. Kim JH, Kim SS, Byun SW, Chang YJ, Kim JS, Kim JK, Cho HJ, Lim KW, Jung ES: [Double strand break of DNA in gastric adenoma and adenocarcinoma]. Korean J Gastroenterol; 2010 Jan;55(1):19-25
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Double strand break of DNA in gastric adenoma and adenocarcinoma].
  • The aim of this study was to define the differences in expression of 53BP1 and gamma-H2AX, the markers of DSB, among normal, gastric adenoma, and gastric adenocarcinoma tissues.
  • METHODS: Tissue microarray was made with the tissues taken from 121 patients who underwent gastrectomy for gastric adenocarcinoma, and 51 patients who underwent endoscopic mucosal resection for gastric adenoma.
  • The normal tissues were collected from histologically confirmed tissues with no cellular atypia obtained from the patients with gastric adenocarcinoma.
  • RESULTS: In gastric carcinoma cells, 53BP1 and gamma-H2AX were highly expressed as compared to normal epithelial cells and gastric adenoma (p<0.01).
  • There were no differences in the expression of 53BP1 and gamma-H2AX between normal epithelium and gastric adenoma.
  • The expression of 53BP1 in the adenoma with grade II and III atypism was more elevated than in those with grade I atypism.
  • The expression of 53BP1 and gamma-H2AX were not significantly different according to the clinicopathologic parameters in the patients with gastric adenocarcinoma.
  • CONCLUSIONS: The DSB in DNA seems to be associated with the development of gastric adenocarcinoma, but does not affect the premalignant adenoma cells.
  • [MeSH-major] Adenocarcinoma / metabolism. Adenoma / metabolism. DNA Breaks, Double-Stranded. Stomach Neoplasms / metabolism

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20098063.001).
  • [ISSN] 1598-9992
  • [Journal-full-title] The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
  • [ISO-abbreviation] Korean J Gastroenterol
  • [Language] kor
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Chemical-registry-number] 0 / H2AFX protein, human; 0 / Histones; 0 / Intracellular Signaling Peptides and Proteins; 0 / TP53BP1 protein, human; 0 / Tumor Suppressor p53-Binding Protein 1
  •  go-up   go-down


25. Szalóki T, Tóth V, Tiszlavicz L, Czakó L: Flat gastric polyps: results of forceps biopsy, endoscopic mucosal resection, and long-term follow-up. Scand J Gastroenterol; 2006 Sep;41(9):1105-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Flat gastric polyps: results of forceps biopsy, endoscopic mucosal resection, and long-term follow-up.
  • OBJECTIVE: Histological examination of specimens obtained by forceps biopsy sampling of gastric polyps is of limited accuracy, and their management on this basis is therefore controversial.
  • The aim of this prospective study was to assess the value of forceps biopsy sampling in establishing the correct diagnosis revealed by endoscopic mucosal resection (EMR).
  • MATERIAL AND METHODS: Subjects with gastric polyps of epithelial origin, of at least 0.5 cm in diameter, and not associated with polyposis syndromes, were included in the study.
  • Between 1994 and 2004, 56 gastric polyps in 44 patients (30 F, 14 M, mean age 67 years) met the inclusion criteria.
  • RESULTS: The initial forceps biopsies identified in situ carcinoma in 3 cases, adenoma with no dysplasia in 19, adenoma with low-grade dysplasia in 2, adenoma with moderate-grade dysplasia in 6, adenoma with high-grade dysplasia in 7, and hyperplastic lesions in 19 cases.
  • The histological examination of the resected polyps revealed in situ carcinoma in 5 cases, carcinoid in 1, gastrointestinal stromal tumor in 1, adenoma with no dysplasia in 14, adenoma with low-grade dysplasia in 3, adenoma with moderate-grade dysplasia in 9, adenoma with high-grade dysplasia in 1, hyperplastic lesions in 21, and no diagnosis in 1 case.
  • CONCLUSIONS: Forceps biopsy is not sufficiently reliable for the identification of gastric polyps.
  • These lesions should be fully resected by EMR for a final diagnosis and (depending on the lesion size and type) possibly definitive treatment.
  • [MeSH-major] Endoscopy, Gastrointestinal / methods. Polyps / pathology. Polyps / surgery. Stomach Neoplasms / pathology. Stomach Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biopsy / methods. Diagnosis, Differential. Female. Follow-Up Studies. Gastric Mucosa / surgery. Gastric Mucosa / ultrastructure. Humans. Male. Microscopy, Electron. Middle Aged. Prospective Studies. Time Factors. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16938725.001).
  • [ISSN] 0036-5521
  • [Journal-full-title] Scandinavian journal of gastroenterology
  • [ISO-abbreviation] Scand. J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] Norway
  •  go-up   go-down


26. Yao K, Iwashita A, Tanabe H, Nishimata N, Nagahama T, Maki S, Takaki Y, Hirai F, Hisabe T, Nishimura T, Matsui T: White opaque substance within superficial elevated gastric neoplasia as visualized by magnification endoscopy with narrow-band imaging: a new optical sign for differentiating between adenoma and carcinoma. Gastrointest Endosc; 2008 Sep;68(3):574-80
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] White opaque substance within superficial elevated gastric neoplasia as visualized by magnification endoscopy with narrow-band imaging: a new optical sign for differentiating between adenoma and carcinoma.
  • BACKGROUND: The microvascular pattern (MVP) as visualized by magnification endoscopy (ME) is a reliable marker for differentiating between benign and malignant gastric flat lesions.
  • However, in cases of gastric neoplasia of 0-IIa type, it is sometimes impossible to visualize the MVP because a white opaque substance (WOS) obscures the subepithelial MVP.
  • OBJECTIVE: To investigate whether the morphology of the WOS could be a useful optical sign for discriminating between adenoma and carcinoma.
  • MATERIALS: Forty-six gastric neoplasias of only 0-IIa type (18 adenomas and 28 early carcinomas) were evaluated.
  • INTERVENTION: The prevalence and the morphology of the WOS as visualized by ME with narrow-band imaging (NBI) according to histologic type (adenoma vs carcinoma).
  • RESULTS: In cases in which a neoplasia of 0-IIa type showed either WOS with a regular distribution or a regular MVP, the sensitivity and specificity for discriminating adenoma from carcinoma were 94% and 96%, respectively.
  • CONCLUSION: In cases in which the WOS is observed, rather than assessing the MVP, morphologic analysis of the WOS could be an alternative new optical sign for discriminating adenoma from carcinoma when using ME with NBI.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma / pathology. Gastroscopy / methods. Radiographic Magnification. Stomach Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biopsy, Needle. Cohort Studies. Diagnosis, Differential. Female. Gastric Mucosa / blood supply. Gastric Mucosa / pathology. Humans. Image Enhancement / methods. Immunohistochemistry. Male. Microcirculation. Middle Aged. Neoplasm Staging. Probability. Sensitivity and Specificity

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Gastrointest Endosc. 2009 Aug;70(2):402; author reply 402-3 [19631809.001]
  • (PMID = 18656862.001).
  • [ISSN] 1097-6779
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


27. Jang JS, Lee EJ, Lee SW, Lee JH, Roh MH, Han SY, Choi SR, Jeong JS: [Endoscopic submucosal dissection for early gastric cancer and gastric adenoma]. Korean J Gastroenterol; 2007 Jun;49(6):356-63
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Endoscopic submucosal dissection for early gastric cancer and gastric adenoma].
  • The aims of this study were to assess the therapeutic efficacy and the safety of ESD in gastric adenoma and in early gastric cancer (EGC).
  • CONCLUSIONS: ESD with IT knife is effective for the treatment of EGC and gastric adenoma even in large or in malignant lesions without definite increased risk of complications.
  • [MeSH-major] Adenoma / surgery. Gastric Mucosa / surgery. Gastroscopy. Stomach Neoplasms / surgery

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17641553.001).
  • [ISSN] 1598-9992
  • [Journal-full-title] The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
  • [ISO-abbreviation] Korean J Gastroenterol
  • [Language] kor
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Korea (South)
  •  go-up   go-down


28. Nagasaka T, Tanaka N, Cullings HM, Sun DS, Sasamoto H, Uchida T, Koi M, Nishida N, Naomoto Y, Boland CR, Matsubara N, Goel A: Analysis of fecal DNA methylation to detect gastrointestinal neoplasia. J Natl Cancer Inst; 2009 Sep 16;101(18):1244-58
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: We first analyzed methylation of the RASSF2 and SFRP2 gene promoters from 788 primary gastric and colorectal tissue specimens to determine whether methylation patterns could act as stage-dependent biomarkers of gastrointestinal tumorigenesis.
  • Methylation of the RASSF2 and SFRP2 promoters was analyzed in 296 fecal samples obtained from a variety of patients, including 21 with gastric tumors, 152 with colorectal tumors, and 10 with non-neoplastic or inflammatory lesions in the gastrointestinal lumen.
  • RESULTS: Analysis of DNA from tissues showed presence of extensive methylation in both gene promoters exclusively in advanced gastric and colorectal tumors.
  • The assay successfully identified one or more methylated markers in fecal DNA from 57.1% of patients with gastric cancer, 75.0% of patients with colorectal cancer, and 44.4% of patients with advanced colorectal adenomas, but only 10.6% of subjects without neoplastic or active diseases (difference, gastric cancer vs undiseased = 46.5%, 95% confidence interval (CI) = 24.6% to 68.4%, P < .001; difference, colorectal cancer vs undiseased = 64.4%, 95% CI = 53.5% to 75.2%, P < .001; difference, colorectal adenoma vs undiseased = 33.8%, 95% CI = 14.2% to 53.4%, P < .001).
  • Our novel fecal DNA methylation assay provides a possible means to noninvasively screen not only for colorectal tumors but also for gastric tumors.

  • MedlinePlus Health Information. consumer health - Bowel Movement.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] CA Cancer J Clin. 2005 Mar-Apr;55(2):74-108 [15761078.001]
  • [Cites] Gastroenterology. 1997 Feb;112(2):594-642 [9024315.001]
  • [Cites] Nat Cell Biol. 1999 Sep;1(5):E131-8 [10559956.001]
  • [Cites] Pathol Int. 2000 Apr;50(4):273-9 [10849312.001]
  • [Cites] Gastroenterology. 2000 Nov;119(5):1219-27 [11054379.001]
  • [Cites] N Engl J Med. 2000 Nov 30;343(22):1603-7 [11096167.001]
  • [Cites] J Natl Cancer Inst. 2001 Jun 6;93(11):858-65 [11390535.001]
  • [Cites] Curr Opin Cell Biol. 2001 Oct;13(5):555-62 [11544023.001]
  • [Cites] N Engl J Med. 2002 Jan 31;346(5):311-20 [11821507.001]
  • [Cites] Nat Genet. 2002 Jun;31(2):141-9 [11992124.001]
  • [Cites] Lancet. 2003 Feb 8;361(9356):512-9 [12583961.001]
  • [Cites] N Engl J Med. 2003 Nov 20;349(21):2042-54 [14627790.001]
  • [Cites] J Biol Chem. 2003 Dec 26;278(52):52401-5 [14561758.001]
  • [Cites] Lancet. 2004 Apr 17;363(9417):1283-5 [15094274.001]
  • [Cites] Biometrics. 1988 Sep;44(3):837-45 [3203132.001]
  • [Cites] Science. 1992 Apr 3;256(5053):102-5 [1566048.001]
  • [Cites] Int J Cancer. 1992 Sep 30;52(3):347-50 [1383164.001]
  • [Cites] Virchows Arch. 1998 May;432(5):415-26 [9645440.001]
  • [Cites] Nat Genet. 1999 Feb;21(2):163-7 [9988266.001]
  • [Cites] N Engl J Med. 2004 Dec 23;351(26):2704-14 [15616205.001]
  • [Cites] Gastroenterology. 2005 Jan;128(1):192-206 [15633136.001]
  • [Cites] Clin Gastroenterol Hepatol. 2005 Feb;3(2):142-9 [15704048.001]
  • [Cites] Clin Cancer Res. 2005 Feb 1;11(3):1203-9 [15709190.001]
  • [Cites] Nat Rev Cancer. 2005 Mar;5(3):223-31 [15719030.001]
  • [Cites] Nucleic Acids Res. 1997 Jun 15;25(12):2532-4 [9171110.001]
  • [Cites] Gastroenterology. 2005 Jul;129(1):156-69 [16012945.001]
  • [Cites] J Natl Cancer Inst. 2005 Aug 3;97(15):1124-32 [16077070.001]
  • [Cites] Gastroenterology. 2005 Aug;129(2):422-8 [16083699.001]
  • [Cites] J Natl Cancer Inst. 2005 Sep 21;97(18):1330-8 [16174854.001]
  • [Cites] Br J Cancer. 2005 Dec 12;93(12):1395-9 [16265349.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2006 Jun;15(6):1115-9 [16775168.001]
  • [Cites] Clin Gastroenterol Hepatol. 2007 Jan;5(1):111-7 [17161655.001]
  • [Cites] Ann Intern Med. 2007 Feb 20;146(4):244-55 [17310048.001]
  • [Cites] Oncogene. 2007 Jul 12;26(32):4699-713 [17297461.001]
  • [Cites] Dig Dis Sci. 2007 Sep;52(9):2287-91 [17410438.001]
  • [Cites] J Natl Cancer Inst. 2007 Oct 3;99(19):1462-70 [17895475.001]
  • [Cites] Int J Colorectal Dis. 2008 Jan;23(1):15-9 [17639423.001]
  • [Cites] Int J Cancer. 2008 Jun 1;122(11):2429-36 [18240147.001]
  • [Cites] Gastroenterology. 2008 Jun;134(7):1950-60, 1960.e1 [18435933.001]
  • [Cites] Ann Intern Med. 2008 Oct 7;149(7):441-50, W81 [18838724.001]
  • [Cites] Am J Gastroenterol. 2008 Nov;103(11):2862-70 [18759824.001]
  • [Cites] Gastroenterology. 2009 Feb;136(2):459-70 [19026650.001]
  • [Cites] Cancer Res. 2009 Jun 1;69(11):4691-9 [19435926.001]
  • [Cites] J Natl Cancer Inst. 2009 Jul 1;101(13):916-27 [19535783.001]
  • [Cites] N Engl J Med. 1993 May 13;328(19):1365-71 [8474513.001]
  • [Cites] Cancer Res. 1995 May 1;55(9):1811-6 [7728743.001]
  • [Cites] Lancet. 1996 Nov 30;348(9040):1467-71 [8942774.001]
  • [Cites] Lancet. 1996 Nov 30;348(9040):1472-7 [8942775.001]
  • [CommentIn] J Natl Cancer Inst. 2009 Sep 16;101(18):1225-7 [19700654.001]
  • [CommentIn] J Natl Cancer Inst. 2010 Jun 2;102(11):830; author reply 831 [20431085.001]
  • (PMID = 19700653.001).
  • [ISSN] 1460-2105
  • [Journal-full-title] Journal of the National Cancer Institute
  • [ISO-abbreviation] J. Natl. Cancer Inst.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / R01 CA072851; United States / NCI NIH HHS / CA / R01 CA 129286; United States / NCI NIH HHS / CA / R01 CA 72851
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Membrane Proteins; 0 / RASSF2 protein, human; 0 / SFRP2 protein, human; 0 / Sulfites; 0 / Tumor Suppressor Proteins; OJ9787WBLU / hydrogen sulfite
  • [Other-IDs] NLM/ PMC2762745
  •  go-up   go-down


29. Carmack SW, Genta RM, Graham DY, Lauwers GY: Management of gastric polyps: a pathology-based guide for gastroenterologists. Nat Rev Gastroenterol Hepatol; 2009 Jun;6(6):331-41
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Management of gastric polyps: a pathology-based guide for gastroenterologists.
  • 1-4% of patients who undergo gastric biopsy have gastric polyps.
  • Hyperplastic polyps, which arise in patients with underlying gastritis, and fundic-gland polyps, which are associated with PPI therapy, are the most common gastric polyps; however, prevalence varies widely relative to the local prevalence of Helicobacter pylori infection and use of PPI therapy.
  • Approximately 20% of biopsy specimens identified endoscopically as polyps have no definite pathological diagnosis.
  • Evaluation of the phenotype of the gastric mucosa that surrounds a lesion will provide significant information crucial to the evaluation, diagnosis and management of a patient.
  • The presence of a gastric adenoma should prompt the search for a coexistent carcinoma.
  • The endoscopic characteristics, histopathology, pathogenesis, and management recommendations of polyps and common polypoid lesions in the stomach are discussed in this Review.
  • [MeSH-major] Adenoma / pathology. Adenoma / therapy. Polyps / pathology. Polyps / therapy. Stomach Neoplasms / pathology. Stomach Neoplasms / therapy
  • [MeSH-minor] Biopsy. Education, Medical, Continuing. Gastritis / epidemiology. Gastritis / pathology. Gastritis / therapy. Gastroenterology. Helicobacter Infections / epidemiology. Helicobacter Infections / pathology. Helicobacter Infections / therapy. Humans. Stomach / pathology

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19421245.001).
  • [ISSN] 1759-5053
  • [Journal-full-title] Nature reviews. Gastroenterology & hepatology
  • [ISO-abbreviation] Nat Rev Gastroenterol Hepatol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 84
  •  go-up   go-down


30. Mine T: The role of magnifying endoscopy in the diagnosis of early gastric carcinoma. J Gastroenterol; 2006 Apr;41(4):397-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The role of magnifying endoscopy in the diagnosis of early gastric carcinoma.
  • [MeSH-major] Adenoma / pathology. Carcinoma / pathology. Endoscopy, Gastrointestinal / methods. Image Enhancement. Stomach Neoplasms / pathology
  • [MeSH-minor] Biopsy. Diagnosis, Differential. Humans. Neoplasm Staging. Video Recording

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentOn] J Gastroenterol. 2006 Apr;41(4):332-8 [16741612.001]
  • [Cites] Gut. 2003 Jan;52(1):24-7 [12477754.001]
  • [Cites] Endoscopy. 2005 Dec;37(12):1215-9 [16329020.001]
  • [Cites] Gastrointest Endosc. 2001 May;53(6):559-65 [11323579.001]
  • [Cites] Gastrointest Endosc. 2003 Apr;57(4):498-504 [12665759.001]
  • [Cites] J Gastroenterol. 2006 Apr;41(4):332-8 [16741612.001]
  • [Cites] Gastrointest Endosc. 2000 Dec;52(6):864-6 [11203485.001]
  • [Cites] Endoscopy. 2002 Oct;34(10):772-7 [12244497.001]
  • [Cites] Gastrointest Endosc. 2004 Jul;60(1):79-84 [15229430.001]
  • [Cites] J Gastroenterol. 2005 May;40(5):443-52 [15942708.001]
  • [Cites] Gastrointest Endosc. 2005 Jul;62(1):48-54 [15990819.001]
  • (PMID = 16741625.001).
  • [ISSN] 0944-1174
  • [Journal-full-title] Journal of gastroenterology
  • [ISO-abbreviation] J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Comment; Editorial
  • [Publication-country] Japan
  •  go-up   go-down


31. Tate G, Suzuki T, Endo Y, Mitsuya T: A novel mutation of the PTEN gene in a Japanese patient with Cowden syndrome and bilateral breast cancer. Cancer Genet Cytogenet; 2008 Jul;184(1):67-71
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In one patient, who suffered from bilateral breast cancer, thyroid adenoma, and gastric malignant lymphoma, we found a single-base substitution in exon 2 (115G>C) of the PTEN gene.
  • [MeSH-minor] Adenoma / complications. Adenoma / genetics. Base Sequence. DNA Primers. Female. Humans. Polymerase Chain Reaction. Thyroid Neoplasms / complications. Thyroid Neoplasms / genetics


32. Joo MK, Park JJ, Lee WW, Lee BJ, Hwang JK, Kim SH, Jung W, Kim JH, Yeon JE, Kim JS, Byun KS, Bak YT: Differences in the prevalence of colorectal polyps in patients undergoing endoscopic removal of gastric adenoma or early gastric cancer and in healthy individuals. Endoscopy; 2010 Feb;42(2):114-20
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Differences in the prevalence of colorectal polyps in patients undergoing endoscopic removal of gastric adenoma or early gastric cancer and in healthy individuals.
  • BACKGROUND AND AIMS: We compared the prevalence of adenomatous and cancerous colon polyps in patients who underwent endoscopic removal of gastric neoplasms and in healthy controls.
  • MATERIALS AND METHODS: This retrospective study reviewed the medical records of 186 patients with gastric neoplasms and 186 healthy subjects from January 2002 to October 2008.
  • The gastric neoplasm group was comprised of patients undergoing endoscopic removal of gastric adenomas or early gastric cancers and serial fiberoptic colonoscopy (FCS) for checkups.
  • The control group was comprised of subjects undergoing fiberoptic esophagogastroduodenoscopy (FEGD) and FCS for general checkup and was matched for age and sex with the gastric neoplasm group.
  • The overall prevalence of adenomatous or cancerous polyps ("all polyps") and the prevalence of advanced colonic neoplasms were significantly higher in the gastric neoplasm group than in the control group (all polyps: 40.9 % in the gastric neoplasm group vs. 25.8 % in the control group, P = 0.002; advanced colonic neoplasms: 15.6 % vs. 8.1 %, P = 0.025).
  • The risk factors for all polyps were age, male sex, diabetes mellitus, and being assigned to the gastric neoplasm group, and those for advanced colonic neoplasms were age and being assigned to the gastric neoplasm group.
  • Confining the analysis to the gastric neoplasm group, the risk factors for all polyps were identical with those for the total group; however, those for advanced colonic neoplasm were different (age vs. diabetes and hypertriglyceridemia).
  • CONCLUSION: Endoscopists should consider performing routine FCS in patients undergoing endoscopic removal of gastric neoplasms.
  • [MeSH-major] Adenoma / surgery. Colonic Polyps / epidemiology. Gastrectomy / methods. Gastroscopy / methods. Stomach Neoplasms / surgery

  • Genetic Alliance. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Colonic Polyps.
  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) Georg Thieme Verlag KG Stuttgart . New York.
  • (PMID = 20140828.001).
  • [ISSN] 1438-8812
  • [Journal-full-title] Endoscopy
  • [ISO-abbreviation] Endoscopy
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


33. Sakai Y, Eto R, Kasanuki J, Kondo F, Kato K, Arai M, Suzuki T, Kobayashi M, Matsumura T, Bekku D, Ito K, Nakamoto S, Tanaka T, Yokosuka O: Chromoendoscopy with indigo carmine dye added to acetic acid in the diagnosis of gastric neoplasia: a prospective comparative study. Gastrointest Endosc; 2008 Oct;68(4):635-41
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Chromoendoscopy with indigo carmine dye added to acetic acid in the diagnosis of gastric neoplasia: a prospective comparative study.
  • BACKGROUND: Conventional endoscopy and chromoendoscopy with indigo carmine dye are usually performed for recognizing adequate tumor-negative lateral margins for successful endoscopic resection of gastric neoplasia.
  • PATIENTS: Forty-seven consecutive patients (53 lesions) with early gastric cancer and gastric adenomas who underwent endoscopic submucosal dissection (ESD) from April 2006 to July 2007 were studied.
  • The applicability of this method for gastric neoplasia merits further investigation.
  • [MeSH-major] Acetic Acid. Endoscopy / methods. Indigo Carmine. Stomach Neoplasms / pathology
  • [MeSH-minor] Adenoma / surgery. Adult. Aged. Aged, 80 and over. Female. Gastroscopy / methods. Humans. Male. Middle Aged. Observer Variation. Prospective Studies

  • MedlinePlus Health Information. consumer health - Endoscopy.
  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • Hazardous Substances Data Bank. INDIGO .
  • Hazardous Substances Data Bank. ACETIC ACID .
  • Hazardous Substances Data Bank. Indigotindisulfonate sodium .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Gastrointest Endosc. 2009 Jun;69(7):1407-8 [19481666.001]
  • (PMID = 18561923.001).
  • [ISSN] 1097-6779
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] D3741U8K7L / Indigo Carmine; Q40Q9N063P / Acetic Acid
  •  go-up   go-down


34. Wheeler YY, Stoll LM, Sheth S, Li QK: Metastatic signet ring cell carcinoma presenting as a thyroid nodule: report of a case with fine-needle aspiration cytology. Diagn Cytopathol; 2010 Aug;38(8):597-602
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Herein, we report a case of metastatic gastric signet ring cell carcinoma to the thyroid.
  • These cytological features may be seen in cases of papillary thyroid carcinoma or signet ring cell follicular adenoma; however, the presence of the signet ring cells is unusual in primary thyroid lesions and raises the possibility of a metastatic lesion to the thyroid.
  • The patient was also found to have a 3.7-cm mass in the distal esophagus/proximal stomach.
  • The purpose of our study is to discuss the cytological features and the differential diagnosis of this unusual thyroid FNA case.
  • [MeSH-minor] Aged. Biopsy, Fine-Needle. Humans. Immunohistochemistry. Male. Stomach Neoplasms / pathology

  • Genetic Alliance. consumer health - Signet ring cell carcinoma.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] 2009 Wiley-Liss, Inc.
  • (PMID = 20014306.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


35. Kang HJ, Park DY, Kim KH, Song GA, Lauwers GY: [Pathologic diagnosis of gastric epithelial neoplasia]. Korean J Gastroenterol; 2008 Nov;52(5):273-80
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pathologic diagnosis of gastric epithelial neoplasia].
  • Gastric epithelial neoplasia is a very common disease entity in Korea, encompassing gastric adenoma and adenocarcinoma.
  • There are still discrepancies in pathologic diagnosis of gastric epithelial neoplasia between Western and Japanese pathologists after Vienna consensus classification.
  • With increasing use of endoscopic therapy such as endoscopic mucosal resection and endoscopic submucosal dissection, it is very important to agree on the consensus criteria in the diagnosis of gastric epithelial neoplasia among pathologists in Korea.
  • On this background, the current concepts, and contemporary issues of definition, diagnostic and classification criteria of gastric epithelial neoplasia were reviewed.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma / pathology. Stomach Neoplasms / pathology. Terminology as Topic

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19077472.001).
  • [ISSN] 1598-9992
  • [Journal-full-title] The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
  • [ISO-abbreviation] Korean J Gastroenterol
  • [Language] kor
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Korea (South)
  • [Number-of-references] 25
  •  go-up   go-down


36. Lee SW, Kang SB, Kim YS, Nam SW, Lee DS, Lee HK, Han SW: [Expression of c-erbB-2 and c-met proteins in gastric adenoma and adenocarcinoma]. Korean J Gastroenterol; 2007 Mar;49(3):152-7
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Expression of c-erbB-2 and c-met proteins in gastric adenoma and adenocarcinoma].
  • BACKGROUND/AIMS: The aim of this study was to investigate the immunohistochemical overexpression of c-erbB-2 and c-met proteins according to the histopathological parameters such as grade of dysplasia, histological type, depth of invasion, lymph node metastasis, and TNM stage in gastric adenoma and gastric adenocarcinoma.
  • In adenoma, the expression rate of c-met was higher in high grade dysplasia (94%) than in low grade dysplasia (22%).
  • CONCLUSIONS: c-erbB-2 would be involved in the development of relatively early stage gastric carcinogenesis. c-erbB-2 is related with histologic type and c-met with lymph node metastasis in gastric carcinomas.
  • Although meaning for the expression of these proteins in gastric carcinomas would be different, these proteins may play as important oncogenes in gastric carcinogenesis.
  • [MeSH-major] Adenocarcinoma / metabolism. Adenoma / metabolism. Proto-Oncogene Proteins c-met / metabolism. Receptor, ErbB-2 / metabolism. Stomach Neoplasms / metabolism


37. Li WB, Zuo XL, Zuo F, Gu XM, Yu T, Zhao YA, Zhang TG, Zhang JP, Li YQ: Characterization and identification of gastric hyperplastic polyps and adenomas by confocal laser endomicroscopy. Surg Endosc; 2010 Mar;24(3):517-24
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Characterization and identification of gastric hyperplastic polyps and adenomas by confocal laser endomicroscopy.
  • BACKGROUND: Management of gastric polyps depends on their histologic composition.
  • A real-time in vivo histologic diagnosis would be valuable to an "on table" management decision.
  • This study aimed to assess the feasibility and practicability of using CLE to identify and differentiate gastric hyperplastic polyps and adenomas.
  • The CLE imaging of hyperplastic polyps and adenomas was performed, and the CLE diagnosis was compared with the gold standard of histopathologic diagnosis.
  • RESULTS: Imaging by CLE was successfully performed for 60 lesions of gastric hyperplastic polyps and 27 lesions of gastric adenomas.
  • Compared with the surrounding background mucosa, gastric hyperplastic polyps and adenomas showed typical distinct appearances, respectively, by CLE.
  • The overall accuracy of the in vivo CLE diagnosis of gastric hyperplastic polyps and adenomas during ongoing endoscopy was 90% (95% confidence interval [CI], 83-96%), and the overall accuracy of differentiating gastric hyperplastic polyps and adenomas by CLE was 97% (95% CI, 90-99%) after endoscopy.
  • CONCLUSIONS: This study characterized confocal images of gastric hyperplastic polyps and adenomas as well as the high accuracy of differentiating hyperplastic polyps and adenomas using CLE.
  • [MeSH-major] Adenoma / pathology. Gastric Mucosa / pathology. Microscopy, Confocal. Polyps / pathology. Stomach Neoplasms / pathology
  • [MeSH-minor] Acriflavine. Adolescent. Adult. Aged. Aged, 80 and over. Confidence Intervals. Diagnosis, Differential. Female. Fluorescent Dyes. Gastroscopy. Humans. Male. Metaplasia / pathology. Middle Aged. Precancerous Conditions / pathology. Risk Factors

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Gut. 2002 Jul;51(1):130-1 [12077106.001]
  • [Cites] Gastroenterology. 2004 Sep;127(3):706-13 [15362025.001]
  • [Cites] Clin Gastroenterol Hepatol. 2006 Aug;4(8):979-87 [16843068.001]
  • [Cites] Virchows Arch. 2000 Dec;437(6):581-90 [11193468.001]
  • [Cites] Endoscopy. 2006 Sep;38(9):886-90 [16981104.001]
  • [Cites] Curr Opin Ophthalmol. 2000 Aug;11(4):241-7 [10977768.001]
  • [Cites] Gut. 2002 Apr;50(4):465-70 [11889063.001]
  • [Cites] Scand J Gastroenterol. 2006 Sep;41(9):1105-9 [16938725.001]
  • [Cites] Am J Gastroenterol. 1995 Dec;90(12):2152-9 [8540506.001]
  • [Cites] Endoscopy. 2008 Jul;40(7):547-53 [18618938.001]
  • [Cites] Endoscopy. 2006 Nov;38(11):1110-4 [17111332.001]
  • [Cites] Am J Clin Pathol. 1986 Oct;86(4):498-503 [3020962.001]
  • [Cites] Virchows Arch. 2003 Feb;442(2):99-106 [12596058.001]
  • [Cites] Endoscopy. 1994 Oct;26(8):659-65 [7859674.001]
  • [Cites] J Clin Gastroenterol. 1989 Feb;11(1):110-5 [2921485.001]
  • [Cites] Gastrointest Endosc. 2008 May;67(6):843-53 [18440377.001]
  • [Cites] Endoscopy. 1981 Nov;13(6):234-7 [7297511.001]
  • [Cites] J Formos Med Assoc. 1991 Apr;90(4):371-4 [1680966.001]
  • [Cites] J Clin Gastroenterol. 2003 May-Jun;36(5):399-402 [12702980.001]
  • [Cites] Arch Pathol Lab Med. 2008 Apr;132(4):633-40 [18384215.001]
  • [Cites] Nature. 1963 Nov 9;200:534-6 [14082218.001]
  • [Cites] Endoscopy. 1981 Sep;13(5):192-6 [7274167.001]
  • [Cites] Gastrointest Endosc. 1992 Jul-Aug;38(4):481-4 [1511825.001]
  • [Cites] J Gastroenterol Hepatol. 2008 Jan;23(1):56-61 [18028347.001]
  • (PMID = 19597774.001).
  • [ISSN] 1432-2218
  • [Journal-full-title] Surgical endoscopy
  • [ISO-abbreviation] Surg Endosc
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Fluorescent Dyes; 1T3A50395T / Acriflavine
  •  go-up   go-down


38. Tamai N, Kaise M, Nakayoshi T, Katoh M, Sumiyama K, Gohda K, Yamasaki T, Arakawa H, Tajiri H: Clinical and endoscopic characterization of depressed gastric adenoma. Endoscopy; 2006 Apr;38(4):391-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical and endoscopic characterization of depressed gastric adenoma.
  • BACKGROUND AND STUDY AIM: Depressed gastric adenoma remains poorly characterized because it is rare, and is infrequently detected by endoscopy.
  • The aim of this study was to elucidate clinical and endoscopic characteristics of depressed adenoma of the stomach.
  • PATIENTS AND METHODS: 95 consecutive patients who underwent endoscopic resection of gastric adenomas were studied.
  • Gastric adenomas, diagnosed according to the Vienna classification, were endoscopically classified into two types: depressed and protruding adenomas.
  • In order to clarify endoscopic features of gastric adenomas, we performed indigo carmine chromoendoscopy as well as magnifying endoscopy with narrow band imaging, which yields clear images of mucosal microvasculature.
  • RESULTS: 12% of 100 gastric adenomas resected from 95 patients were depressed adenomas.
  • [MeSH-major] Adenoma / pathology. Endoscopy, Gastrointestinal / methods. Gastric Mucosa / pathology. Stomach Neoplasms / pathology
  • [MeSH-minor] Aged. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Male. Middle Aged. Retrospective Studies

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16680640.001).
  • [ISSN] 0013-726X
  • [Journal-full-title] Endoscopy
  • [ISO-abbreviation] Endoscopy
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


39. Jung JT, Lee CH, You SS, Ha HK, Bae JS, Kwon JG, Kim EY, Kim HG, Cho CH, Shin IH: [Grading of histology, expression of apoptosis and cell proliferation in gastric mucosa adjacent to gastric adenoma or adenocarcinoma]. Korean J Gastroenterol; 2005 Oct;46(4):269-75
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Grading of histology, expression of apoptosis and cell proliferation in gastric mucosa adjacent to gastric adenoma or adenocarcinoma].
  • BACKGROUND/AIMS: Helicobacter pylori (H. pylori) infection can lead to gastric adenoma and carcinoma through atrophic gastritis and intestinal metaplasia.
  • Imbalance between apoptosis and proliferation may play a role in gastric carcinogenesis.
  • We tried to investigate H. pylori infection rate, grade of gastritis, environmental risk factors, expression rate of apoptosis and cell proliferation in mucosa adjacent to tumor, and we also tried to find significant factors associated with gastric carcinogenesis.
  • METHODS: Endoscopically diagnosed twenty cases of intestinal type gastric carcinoma, 20 cases of gastric adenoma, and 40 cases of control (normal or gastritis) were enrolled. H. pylori infection rate, histologic grading, apoptosis and immunohistochemical stain (Ki-67 and p53) to check mucosal proliferation were done in endoscopically biopsied tissues at antrum and body at least 2 cm apart from adenoma or carcinoma.
  • In the multivariate analysis, only atrophy of gland was a significant risk factor for adenoma compared to control group (OR 3.7).
  • CONCLUSIONS: Intestinal metaplasia in antrum and alcohol drinking are significant risk factors for gastric carcinoma.
  • Degree of mucosal proliferation and apoptosis in gastric mucosa adjacent to tumor are not significantly different in three groups.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma / pathology. Apoptosis. Cell Proliferation. Gastric Mucosa / pathology. Stomach Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16247270.001).
  • [ISSN] 1598-9992
  • [Journal-full-title] The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
  • [ISO-abbreviation] Korean J Gastroenterol
  • [Language] kor
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Korea (South)
  •  go-up   go-down


40. Nakamura M, Shibata T, Tahara T, Yoshioka D, Okubo M, Mizoguchi Y, Kuroda M, Arisawa T, Hirata I: The usefulness of magnifying endoscopy with narrow-band imaging to distinguish carcinoma in flat elevated lesions in the stomach diagnosed as adenoma by using biopsy samples. Gastrointest Endosc; 2010 May;71(6):1070-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The usefulness of magnifying endoscopy with narrow-band imaging to distinguish carcinoma in flat elevated lesions in the stomach diagnosed as adenoma by using biopsy samples.
  • BACKGROUND: Therapeutic strategies for flat elevated (0-IIa) lesions in the stomach diagnosed as adenoma by biopsy are currently not established, because some difficulties have previously been reported in the evaluation of vascular patterns alone for the differential diagnosis between adenoma and carcinoma.
  • OBJECTIVE: We attempted to evaluate the 0-IIa lesions diagnosed as adenoma by using magnifying endoscopy with narrow-band imaging (MENBI) to distinguish them as either adenoma or carcinoma.
  • MAIN OUTCOME MEASUREMENTS: The rate of SSs and IMVPs in adenoma and carcinoma.
  • RESULTS: Significant SSs were tubular in the adenoma and unclear in the carcinoma.
  • CONCLUSIONS: Our combined evaluation method using MENBI offers the ability to establish proper therapeutic strategies for lesions that are difficult to identify as adenoma or carcinoma.
  • [MeSH-major] Adenoma / diagnosis. Gastroscopy / methods. Stomach / pathology. Stomach Neoplasms / diagnosis
  • [MeSH-minor] Biopsy. Diagnosis, Differential. Dissection. Gastric Mucosa / surgery. Humans. Image Enhancement. Retrospective Studies

  • Genetic Alliance. consumer health - Stomach carcinoma.
  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] 2010 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved.
  • (PMID = 20438898.001).
  • [ISSN] 1097-6779
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


41. Swain JM, Adams RB, Farnell MB, Que FG, Sarr MG: Gastric and pancreatoduodenal resection for malignant lesions after previous gastric bypass--diagnosis and methods of reconstruction. Surg Obes Relat Dis; 2010 Nov-Dec;6(6):670-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gastric and pancreatoduodenal resection for malignant lesions after previous gastric bypass--diagnosis and methods of reconstruction.
  • BACKGROUND: The diagnosis and treatment of gastric and pancreatoduodenal neoplasms after previous gastric bypass has been limited.
  • The diagnosis and resection of these neoplasms and restoration of biliopancreatic intestinal continuity pose challenges.
  • We present a 2-institutional experience of diagnosis and reconstruction after resection of gastric and pancreatoduodenal neoplasms and discuss the technical options for reconstruction.
  • METHODS: The medical records were reviewed retrospectively from 2003 to 2009 for patients with previous gastric bypass who developed a gastric or pancreatoduodenal neoplasm.
  • RESULTS: Of the available patients, 7 were identified with 2 remnant gastric cancers (2 signet ring cell adenocarcinomas), 4 pancreatic neoplasms (2 adenocarcinomas and 2 neuroendocrine cancers), and 1 ampullary cancer.
  • The gastric neoplasms required complete remnant gastrectomy but did not require additional gastrointestinal reconstruction.
  • CONCLUSION: Gastric and pancreatoduodenal neoplasms after previous gastric bypass, although rare, will most likely increase as the number of bariatric operations increases.
  • Resection is feasible and safe but could require complex gastric and pancreatobiliary reconstruction.
  • [MeSH-major] Digestive System Surgical Procedures / methods. Duodenal Neoplasms / surgery. Gastrectomy / methods. Gastric Bypass. Pancreatic Neoplasms / surgery. Pancreaticoduodenectomy / methods. Stomach Neoplasms / surgery
  • [MeSH-minor] Adenoma, Islet Cell / diagnosis. Adenoma, Islet Cell / epidemiology. Adenoma, Islet Cell / surgery. Aged. Carcinoma, Neuroendocrine / diagnosis. Carcinoma, Neuroendocrine / epidemiology. Carcinoma, Neuroendocrine / surgery. Common Bile Duct Neoplasms / diagnosis. Common Bile Duct Neoplasms / epidemiology. Common Bile Duct Neoplasms / surgery. Female. Humans. Male. Middle Aged. Retrospective Studies

  • MedlinePlus Health Information. consumer health - Intestinal Cancer.
  • MedlinePlus Health Information. consumer health - Pancreatic Cancer.
  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2010 American Society for Metabolic and Bariatric Surgery. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20627707.001).
  • [ISSN] 1878-7533
  • [Journal-full-title] Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
  • [ISO-abbreviation] Surg Obes Relat Dis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


42. Rocco A, Caruso R, Toracchio S, Rigoli L, Verginelli F, Catalano T, Neri M, Curia MC, Ottini L, Agnese V, Bazan V, Russo A, Pantuso G, Colucci G, Mariani-Costantini R, Nardone G: Gastric adenomas: relationship between clinicopathological findings, Helicobacter pylori infection, APC mutations and COX-2 expression. Ann Oncol; 2006 Jun;17 Suppl 7:vii103-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gastric adenomas: relationship between clinicopathological findings, Helicobacter pylori infection, APC mutations and COX-2 expression.
  • Gastric adenomas are rare neoplastic growths characterized by localized polypoid proliferations of dysplastic epithelium that tend to progress to infiltrating adenocarcinoma.
  • In this study we investigated, in a series of gastric adenoma specimens from an area at high risk of gastric cancer, the relationship between clinicopathological characteristics of adenoma and Helicobacter pylori infection, APC mutational status, and COX-2 and the down-stream enzyme mPGES1 expression.
  • Pathogenetic mutations of MCR region (codons 1269-1589) of the APC gene were detected only in one case corresponding to a single, small size, low grade, H. pylori-negative adenoma.
  • In conclusion, COX-2 may play a key role in the development and progression of gastric adenoma and could be an attractive target in the management of gastric adenoma at major risk of cancer development.

  • MedlinePlus Health Information. consumer health - Helicobacter Pylori Infections.
  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16760271.001).
  • [ISSN] 1569-8041
  • [Journal-full-title] Annals of oncology : official journal of the European Society for Medical Oncology
  • [ISO-abbreviation] Ann. Oncol.
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] EC 1.14.99.1 / Cyclooxygenase 2; EC 5.3.- / Intramolecular Oxidoreductases; EC 5.3.99.3 / prostaglandin-E synthase
  •  go-up   go-down


43. Wang SY, Cheng MF, Tzen KY, Yen RF: F-18 fluorodeoxyglucose uptake in gastric adenoma after stomach distention by water. Clin Nucl Med; 2008 Sep;33(9):643-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] F-18 fluorodeoxyglucose uptake in gastric adenoma after stomach distention by water.
  • [MeSH-major] Adenoma / metabolism. Adenoma / physiopathology. Fluorodeoxyglucose F18 / metabolism. Stomach / physiopathology. Stomach Neoplasms / metabolism. Stomach Neoplasms / physiopathology. Water / pharmacology

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • Hazardous Substances Data Bank. Water .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18716520.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 059QF0KO0R / Water; 0Z5B2CJX4D / Fluorodeoxyglucose F18
  •  go-up   go-down


44. Lee HS, Choe G, Park KU, Park DJ, Yang HK, Lee BL, Kim WH: Altered expression of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) during gastric carcinogenesis and its clinical implications on gastric cancer. Int J Oncol; 2007 Oct;31(4):859-66
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Altered expression of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) during gastric carcinogenesis and its clinical implications on gastric cancer.
  • To determine the protein expression and clinical implications of DNA-PKcs in gastric carcinogenesis and cancer progression, we evaluated its expression status by immunohistochemistry in 122 non-neoplastic gastric mucosa samples, and in 115 gastric adenomas and 564 consecutive gastric cancers.
  • In addition, we evaluated the clinicopathologic characteristics of gastric cancers showing altered DNA-PKcs expression, and performed microsatellite instability (MSI) analysis at BAT-26 and frameshift mutation analysis of DNA-PKcs.
  • DNA-PKcs expression was negative in foveolar epithelium of normal gastric mucosal tissues, but was positive in most Helicobacter pylori-associated gastritis, intestinal metaplasia and gastric adenoma tissues.
  • In gastric cancers, negative expression of DNA-PKcs was found in 114 of the 564 (20.2%) cancers and was significantly associated with intratumoral neutrophils, MSI-high (H) phenotype, tumor progression, and poor patient survival (p<0.05).
  • Frameshift mutations of (A)10 mononucleotide repeats in DNA-PKcs were found in 24.3% of MSI-H gastric cancers and these were associated with negative expression of DNA-PKcs.
  • Although patients with MSI-H gastric cancers were found to have a lower risk of lymph node metastasis, gastric cancers harboring the (A)10 mutation of DNA-PKcs were found to have a higher risk of lymph node metastasis.
  • In conclusion, the expression of DNA-PKcs was found to be altered during gastric carcinogenesis and negative DNA-PKcs expression was associated with gastric cancer progression.
  • The (A)10 frameshift mutation of DNA-PKcs in gastric cancers was a target of defective mismatch repair, and was associated with lymph node metastasis.
  • [MeSH-major] Adenocarcinoma / enzymology. DNA-Activated Protein Kinase / genetics. DNA-Activated Protein Kinase / metabolism. Stomach Neoplasms / enzymology
  • [MeSH-minor] Adenocarcinoma, Mucinous / enzymology. Adenocarcinoma, Mucinous / genetics. Adenocarcinoma, Mucinous / virology. Adenoma / enzymology. Adenoma / genetics. Adenoma / virology. DNA Mismatch Repair. Female. Frameshift Mutation. Gastric Mucosa / enzymology. Gastric Mucosa / pathology. Gene Expression Regulation, Neoplastic. Helicobacter Infections / complications. Helicobacter Infections / genetics. Helicobacter Infections / virology. Helicobacter pylori / pathogenicity. Humans. Intestinal Neoplasms / enzymology. Intestinal Neoplasms / genetics. Intestinal Neoplasms / virology. Lymphatic Metastasis / genetics. Male. Metaplasia / enzymology. Metaplasia / genetics. Metaplasia / virology. Microsatellite Instability. Middle Aged. Neoplasm Invasiveness / genetics

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17786318.001).
  • [ISSN] 1019-6439
  • [Journal-full-title] International journal of oncology
  • [ISO-abbreviation] Int. J. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] EC 2.7.11.1 / DNA-Activated Protein Kinase
  •  go-up   go-down


45. Winkler A, Hinterleitner TA, Högenauer C, Hauser H, Langner C: Juvenile polyposis of the stomach causing recurrent upper gastrointestinal bleeding. Eur J Gastroenterol Hepatol; 2007 Jan;19(1):87-90
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Juvenile polyposis of the stomach causing recurrent upper gastrointestinal bleeding.
  • Endoscopy showed multiple glassy polyps in the stomach, which corresponded to a diffuse mucosal thickening detected by endosonography.
  • The resection specimen showed the gastric mucosa carpeted by numerous glassy pedunculated polyps, measuring 2 cm in largest diameter.
  • Colonoscopy including the terminal ileum revealed a single tubulovillous adenoma, but no hamartomatous polyps, rendering a final diagnosis of juvenile polyposis of the stomach.
  • This case represents the first description of juvenile polyposis causing life-threatening gastric haemorrhage.
  • Thus, although rare, the disease has to be considered in the differential diagnosis of patients with acute upper gastrointestinal tract bleeding.
  • [MeSH-major] Adenomatous Polyposis Coli / complications. Gastrointestinal Hemorrhage / etiology. Polyps / complications. Stomach Neoplasms / complications
  • [MeSH-minor] Adult. Gastric Mucosa / pathology. Humans. Male. Recurrence

  • MedlinePlus Health Information. consumer health - Gastrointestinal Bleeding.
  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17206083.001).
  • [ISSN] 0954-691X
  • [Journal-full-title] European journal of gastroenterology & hepatology
  • [ISO-abbreviation] Eur J Gastroenterol Hepatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  •  go-up   go-down


46. Park JH, Lee BL, Yoon J, Kim J, Kim MA, Yang HK, Kim WH: Focal adhesion kinase (FAK) gene amplification and its clinical implications in gastric cancer. Hum Pathol; 2010 Dec;41(12):1664-73
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Focal adhesion kinase (FAK) gene amplification and its clinical implications in gastric cancer.
  • Because the clinical implications of focal adhesion kinase overexpression in gastric cancer have been inconsistent, we extended previous studies and evaluated focal adhesion kinase gene amplification as well as its protein expression.
  • Immunohistochemical tissue array analysis showed that focal adhesion kinase immunoreactivity was present in both the cytoplasm and membrane of gastric cancer cells.
  • Regarding focal adhesion kinase gene amplification, fluorescence in situ hybridization analysis showed focal adhesion kinase gene amplification in 34 (8.9%) of 384 gastric cancer specimens, whereas there was no amplification in any case of atrophy, intestinal metaplasia, or adenoma/dysplasia.
  • In conclusion, our results showed that either focal adhesion kinase protein expression or focal adhesion kinase gene amplification was significantly correlated with cancer progression and poor prognosis in gastric cancer.
  • Thus, focal adhesion kinase gene amplification could supplement its protein expression for the diagnosis and treatment of gastric cancer.
  • [MeSH-major] Adenocarcinoma / genetics. Focal Adhesion Kinase 1 / genetics. Gene Amplification. Stomach Neoplasms / genetics

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20869748.001).
  • [ISSN] 1532-8392
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm; EC 2.7.10.2 / Focal Adhesion Kinase 1; EC 2.7.10.2 / PTK2 protein, human
  •  go-up   go-down


47. Vieth M, Kushima R, de Jonge JP, Borchard F, Oellig F, Stolte M: Adenoma with gastric differentiation (so-called pyloric gland adenoma) in a heterotopic gastric corpus mucosa in the rectum. Virchows Arch; 2005 May;446(5):542-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenoma with gastric differentiation (so-called pyloric gland adenoma) in a heterotopic gastric corpus mucosa in the rectum.
  • In a 46-year-old man, a pedunculated rectal polyp measuring 3.0x3.0x2.0 cm was diagnosed histologically as a pyloric gland-type adenoma arising in heterotopic gastric corpus mucosa.
  • The luminal site was covered by glands of the gastric foveolar type, displaying focal marked proliferation interpreted as low-grade intraepithelial neoplasia.
  • A bidirectional gastric differentiation was found: most lower glandular structures showed positivity for the deep gastric mucin core protein Muc 6 and superficial positivity for gastric foveolar epithelium mucin core protein Muc 5AC.
  • Pyloric gland adenoma has so far been described in one larger series only and a few case reports of the stomach, gallbladder, pancreatic duct and within heterotopic gastric corpus mucosa of the duodenal bulb.
  • The present case report is the first case of a pyloric gland-type adenoma within a gastric corpus heterotopia of the rectal mucosa.
  • [MeSH-major] Adenoma / pathology. Choristoma. Gastric Mucosa. Intestinal Polyps / pathology. Rectal Neoplasms / pathology
  • [MeSH-minor] Cell Division. Humans. Intestinal Mucosa / pathology. Male. Middle Aged. Mucin 5AC. Mucin-6. Mucins / analysis. Stomach Neoplasms / chemistry. Stomach Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Dig Dis Sci. 2003 Nov;48(11):2153-8 [14705821.001]
  • [Cites] Gastrointest Endosc. 2002 Sep;56(3):441-4 [12196793.001]
  • [Cites] Endoscopy. 1995 Jan;27(1):32-7; discussion 59-60 [7601032.001]
  • [Cites] Cancer Res. 1993 Oct 15;53(20):4791-6 [8402663.001]
  • [Cites] Gastric Cancer. 2001;4(4):185-91 [11846061.001]
  • [Cites] Am J Surg Pathol. 1999 Feb;23(2):227-31 [9989851.001]
  • [Cites] Virchows Arch. 2003 Apr;442(4):317-21 [12715167.001]
  • [Cites] Proc Natl Acad Sci U S A. 1999 Jun 22;96(13):7318-23 [10377412.001]
  • [Cites] Virchows Arch. 2002 Feb;440(2):205-8 [11964052.001]
  • [Cites] J Clin Gastroenterol. 1994 Jul;19(1):41-5 [7930432.001]
  • [Cites] Endoscopy. 1986 Jan;18(1):34 [3948806.001]
  • [Cites] Virchows Arch. 1999 Oct;435(4):452-7 [10526011.001]
  • [Cites] Int J Colorectal Dis. 1993 Mar;8(1):9-12 [8492046.001]
  • [Cites] Gastroenterology. 1987 Jan;92(1):243-53 [3536653.001]
  • [Cites] Am J Clin Pathol. 1971 May;55(5):604-16 [5090217.001]
  • [Cites] Gut. 1988 Jun;29(6):848-51 [3290067.001]
  • [Cites] Pathologe. 1987 Jan;8(1):52-5 [3562411.001]
  • [Cites] Histopathology. 1983 Nov;7(6):931-8 [6662511.001]
  • [Cites] Endoscopy. 1994 Oct;26(8):659-65 [7859674.001]
  • [Cites] Pathol Res Pract. 1996 Sep;192(9):963-9; discussion 970-1 [8950764.001]
  • [Cites] Beitr Pathol. 1975 Dec;156(4):343-58 [1220670.001]
  • (PMID = 15838648.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / MUC5AC protein, human; 0 / MUC6 protein, human; 0 / Mucin 5AC; 0 / Mucin-6; 0 / Mucins
  •  go-up   go-down


48. Ding XW, Luo HS, Jin X, Yan JJ, Ai YW: Aberrant expression of Eag1 potassium channels in gastric cancer patients and cell lines. Med Oncol; 2007;24(3):345-50
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Aberrant expression of Eag1 potassium channels in gastric cancer patients and cell lines.
  • The aim of this study is to investigate expression of Eag1 potassium channel in gastric cancer and its role in cancer cells growth.
  • The expression of Eag1 for gasric cancer patients and cell lines as well as gastric adenoma was investigated by immunohistochemistry and reverse transcription polymerase chain reaction.
  • Frequency of positive expression of Eag1 protein was 70.5% (67/95) and Eag1 mRNA was 68.2% (15/22) in gastric cancer primary tissues.
  • Eag1 mRNA was positively expressed in two gastric cell lines.
  • Eag1 protein and mRNA were negatively expressed in paired non-cancerous matched tissues and 5 cases of adenoma tissues.
  • The study indicates Eag1 is aberrantly expressed in gastric cancer tissues and cell lines and associated with cancer lymph node metastasis and stage and play an important role in the proliferation of gastric cancer cells.
  • [MeSH-major] Adenoma / metabolism. Ether-A-Go-Go Potassium Channels / metabolism. Gene Expression Regulation, Neoplastic. Stomach Neoplasms / metabolism
  • [MeSH-minor] Adult. Aged. Case-Control Studies. Cell Line, Tumor. Cell Proliferation. Chi-Square Distribution. Female. Humans. Immunohistochemistry. Lymphatic Metastasis / diagnosis. Male. Matched-Pair Analysis. Middle Aged. Neoplasm Metastasis / physiopathology. RNA, Messenger / analysis. Reference Values

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] EMBO J. 1999 Oct 15;18(20):5540-7 [10523298.001]
  • [Cites] J Gen Physiol. 2004 Oct;124(4):301-17 [15365094.001]
  • [Cites] J Biol Chem. 2006 May 12;281(19):13030-7 [16537547.001]
  • [Cites] Nature. 2006 Mar 23;440(7083):440-7 [16554803.001]
  • [Cites] FEBS Lett. 2006 May 22;580(12):2850-2 [16783874.001]
  • [Cites] Pharmacol Rev. 2005 Dec;57(4):473-508 [16382104.001]
  • [Cites] J Membr Biol. 2002 Jul 15;188(2):137-49 [12172639.001]
  • [Cites] Cancer Lett. 2006 Feb 20;233(1):1-9 [16473665.001]
  • [Cites] FEBS Lett. 1998 Aug 28;434(1-2):177-82 [9738473.001]
  • [Cites] J Membr Biol. 2005 Jun;205(3):115-24 [16362499.001]
  • [Cites] Mol Cancer. 2006 Oct 05;5:42 [17022811.001]
  • [Cites] J Membr Biol. 2001 Jul 1;182(1):1-15 [11426295.001]
  • [Cites] Proc Natl Acad Sci U S A. 1994 Apr 12;91(8):3438-42 [8159766.001]
  • [Cites] Cancer Res. 2004 Oct 1;64(19):6996-7001 [15466192.001]
  • [Cites] Receptors Channels. 2001;7(5):345-56 [11697078.001]
  • [Cites] J Physiol. 1998 Apr 1;508 ( Pt 1):49-56 [9490815.001]
  • [Cites] J Membr Biol. 2005 Jun;205(3):175-84 [16362505.001]
  • (PMID = 17873312.001).
  • [ISSN] 1357-0560
  • [Journal-full-title] Medical oncology (Northwood, London, England)
  • [ISO-abbreviation] Med. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Ether-A-Go-Go Potassium Channels; 0 / KCNH1 protein, human; 0 / RNA, Messenger
  •  go-up   go-down


49. Mohan H, Garg S, Punia RP, Dalal A: Combined serous cystadenoma and pancreatic endocrine neoplasm. A case report with a brief review of the literature. JOP; 2007;8(4):453-7
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This mass went beyond the stomach and above the lesser curvature of the stomach.
  • The diagnosis of combined microcystic adenoma and pancreatic endocrine neoplasm was made.
  • The coexistence of pancreatic endocrine neoplasms with potential malignant behavior may be overshadowed by obvious benign tumors such as a microcystic serous cystadenoma.
  • [MeSH-major] Carcinoma, Pancreatic Ductal / complications. Cystadenoma, Serous / complications. Neoplasms, Multiple Primary / diagnosis. Pancreatic Neoplasms / complications

  • MedlinePlus Health Information. consumer health - Pancreatic Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17625299.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 13
  •  go-up   go-down


50. Rio Frio T, Lavoie J, Hamel N, Geyer FC, Kushner YB, Novak DJ, Wark L, Capelli C, Reis-Filho JS, Mai S, Pastinen T, Tischkowitz MD, Marcus VA, Foulkes WD: Homozygous BUB1B mutation and susceptibility to gastrointestinal neoplasia. N Engl J Med; 2010 Dec 30;363(27):2628-37
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A patient received a diagnosis of adenocarcinoma of the ampulla of Vater at 34 years of age.
  • Two decades later, adenomatous polyps were found, followed by multiple primary invasive adenocarcinomas of both the colon and the stomach.
  • [MeSH-minor] Adenocarcinoma / genetics. Adenoma / genetics. Adenomatous Polyposis Coli Protein / genetics. Adenomatous Polyposis Coli Protein / metabolism. Aged. Chromosome Disorders / genetics. DNA Mutational Analysis. Female. Genomic Instability. Homozygote. Humans. Karyotyping. Male. Mosaicism. Oligonucleotide Array Sequence Analysis. Pedigree. Phenotype. Spindle Apparatus


51. Aretz S, Uhlhaas S, Goergens H, Siberg K, Vogel M, Pagenstecher C, Mangold E, Caspari R, Propping P, Friedl W: MUTYH-associated polyposis: 70 of 71 patients with biallelic mutations present with an attenuated or atypical phenotype. Int J Cancer; 2006 Aug 15;119(4):807-14
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • To determine the frequency, mutation spectrum and phenotype of the recently described autosomal recessive MUTYH-associated polyposis (MAP), we performed a systematic search for MUTYH (MYH) mutations by sequencing the complete coding region of the gene in 329 unselected APC mutation-negative index patients with the clinical diagnosis of familial adenomatous polyposis (FAP) or attenuated FAP (AFAP).
  • Fifty percentage of the MAP patients had colorectal cancer at diagnosis.
  • Duodenal polyposis was found in 18%, thyroid and stomach cancer in 1 case, other extraintestinal manifestations associated with FAP were not observed.
  • [MeSH-minor] Adenoma / genetics. Adolescent. Adult. Aged. Child. Child, Preschool. Colorectal Neoplasms / genetics. Humans. Middle Aged. Phenotype

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2006 Wiley-Liss, Inc.
  • (PMID = 16557584.001).
  • [ISSN] 0020-7136
  • [Journal-full-title] International journal of cancer
  • [ISO-abbreviation] Int. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] EC 3.2.2.- / DNA Glycosylases; EC 3.2.2.- / mutY adenine glycosylase
  •  go-up   go-down


52. Kuroki T, Tajima Y, Tsutsumi R, Mishima T, Kitasato A, Adachi T, Kanematsu T: Inferior branch-preserving superior head resection of the pancreas with gastric wall-covering method for intraductal papillary mucinous adenoma. Am J Surg; 2006 Jun;191(6):823-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Inferior branch-preserving superior head resection of the pancreas with gastric wall-covering method for intraductal papillary mucinous adenoma.
  • We describe a surgical technique of superior head resection of the pancreas with inferior branch preservation followed by a gastric wall-covering method for the prevention of pancreatic leakage in patients with IPMN of the pancreas head.
  • [MeSH-major] Adenocarcinoma, Mucinous / surgery. Carcinoma, Pancreatic Ductal / surgery. Pancreatectomy / methods. Pancreatic Neoplasms / surgery. Stomach / surgery
  • [MeSH-minor] Abdominal Pain / diagnosis. Abdominal Pain / etiology. Aged. Anastomosis, Surgical. Cholangiopancreatography, Endoscopic Retrograde / methods. Follow-Up Studies. Humans. Immunohistochemistry. Male. Neoplasm Staging. Risk Assessment. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Pancreatic Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16720158.001).
  • [ISSN] 0002-9610
  • [Journal-full-title] American journal of surgery
  • [ISO-abbreviation] Am. J. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


53. Kim YJ, Park JC, Kim JH, Shin SK, Lee SK, Lee YC, Chung JB: Histologic diagnosis based on forceps biopsy is not adequate for determining endoscopic treatment of gastric adenomatous lesions. Endoscopy; 2010 Aug;42(8):620-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Histologic diagnosis based on forceps biopsy is not adequate for determining endoscopic treatment of gastric adenomatous lesions.
  • BACKGROUND AND STUDY AIMS: Controversy persists around the treatment of gastric low-grade dysplasia (LGD).
  • The aim of this study was to investigate possible indications for the endoscopic resection of gastric LGD through analysis of the histologic discrepancies between specimens of gastric LGD obtained by forceps biopsy and by endoscopic mucosal resection (EMR), and of their clinicopathologic characteristics.
  • PATIENTS AND METHODS: The study involved 293 gastric LGD that were histologically proven on the basis of forceps biopsy in Severance Hospital between January 2004 and December 2007.
  • CONCLUSIONS: We should consider endoscopic resection for gastric LGD that are 2 cm or more in size and do not have whitish discoloration.
  • [MeSH-major] Adenoma / pathology. Biopsy / methods. Gastric Mucosa / pathology. Gastroscopy. Precancerous Conditions / pathology. Stomach Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Biopsy.
  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Georg Thieme Verlag KG Stuttgart . New York.
  • (PMID = 20623445.001).
  • [ISSN] 1438-8812
  • [Journal-full-title] Endoscopy
  • [ISO-abbreviation] Endoscopy
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


54. Cohen J: Optical contrast endoscopy: is it ready for routine use? Gastroenterology; 2009 Jan;136(1):52-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adenoma / diagnosis. Barrett Esophagus / diagnosis. Biopsy. Colonic Neoplasms / diagnosis. Colonic Polyps / pathology. Esophagus / pathology. Humans. Image Enhancement. Inflammatory Bowel Diseases / diagnosis. Stomach Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Endoscopy.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19063888.001).
  • [ISSN] 1528-0012
  • [Journal-full-title] Gastroenterology
  • [ISO-abbreviation] Gastroenterology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


55. Yagi K, Aruga Y, Nakamura A, Sekine A, Umezu H: The study of dynamic chemical magnifying endoscopy in gastric neoplasia. Gastrointest Endosc; 2005 Dec;62(6):963-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The study of dynamic chemical magnifying endoscopy in gastric neoplasia.
  • BACKGROUND: We assessed the usefulness of acetic acid-enhanced magnifying endoscopy in the diagnosis of gastric neoplasia.
  • METHODS: Forty-five patients (27 men, 18 women; median age 61.6 years) with gastric carcinoma or adenoma were enrolled in a prospective trial of enhanced magnifying endoscopy after instillation of 1.5% acetic acid.
  • Acetic acid-enhanced magnified views of carcinoma or adenoma and the surrounding non-neoplastic mucosa were observed, and the duration of whitening time of each lesion was recorded.
  • The mean duration of whitening differed with each histologic type: low-grade adenoma, 94 seconds; high-grade adenoma, 24.3 seconds; noninvasive carcinoma, 20.1 seconds; invasive intramucosal carcinoma, 3.5 seconds; and submucosal carcinoma or beyond, 2.5 seconds.
  • CONCLUSIONS: Acetic acid-enhanced magnifying endoscopy was useful for the diagnosis of gastric adenocarcinoma.
  • [MeSH-major] Acetic Acid. Gastric Mucosa / pathology. Gastroscopy. Stomach Neoplasms / diagnosis
  • [MeSH-minor] Adenoma / diagnosis. Adenoma / pathology. Carcinoma / diagnosis. Carcinoma / pathology. Female. Humans. Indicators and Reagents. Male

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • Hazardous Substances Data Bank. ACETIC ACID .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16301045.001).
  • [ISSN] 0016-5107
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Indicators and Reagents; Q40Q9N063P / Acetic Acid
  •  go-up   go-down


56. Katsube T, Konnno S, Hamaguchi K, Shimakawa T, Naritaka Y, Ogawa K, Aiba M: The efficacy of endoscopic mucosal resection in the diagnosis and treatment of group III gastric lesions. Anticancer Res; 2005 Sep-Oct;25(5):3513-6
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The efficacy of endoscopic mucosal resection in the diagnosis and treatment of group III gastric lesions.
  • The final diagnosis after EMR broadly classified the lesions as adenocarcinoma or adenoma.
  • RESULTS: Adenocarcinoma was identified in 16 patients (37.2%) and adenoma in 27 patients (62.8%).
  • [MeSH-major] Adenocarcinoma / surgery. Stomach Neoplasms / surgery
  • [MeSH-minor] Adenoma / diagnosis. Adenoma / pathology. Adenoma / surgery. Aged. Biopsy. Endoscopy, Gastrointestinal. Female. Gastric Mucosa / pathology. Gastric Mucosa / surgery. Humans. Male

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16101171.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Greece
  •  go-up   go-down


57. Takasu N, Kimura W, Moriya T, Takeshita A, Murayama S, Hirai I, Ogata S: A pancreatobiliary-type carcinoma in situ at the periphery of a mural nodule developed from a gastric adenoma in an intraductal papillary mucinous neoplasm. Clin J Gastroenterol; 2010 Aug;3(4):209-13
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A pancreatobiliary-type carcinoma in situ at the periphery of a mural nodule developed from a gastric adenoma in an intraductal papillary mucinous neoplasm.
  • We report a rare case of an intraductal papillary mucinous neoplasm (IPMN) with a pancreatobiliary-type carcinoma in situ (CIS) that originated around a mural nodule formed in a gastric-type adenoma.
  • Histopathologic examination showed an intraductal papillary mucinous carcinoma arising from an adenoma.
  • Hematoxylin and eosin (H&E) staining revealed that most of the tumor components, including the mural nodule, had adenomatous changes, indicating the tumor to be of the gastric type; however, immunohistochemistry showed positive MUC2 expression.

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Virchows Arch. 2005 Nov;447(5):794-9 [16088402.001]
  • [Cites] Oncol Rep. 2008 Jun;19(6):1435-43 [18497948.001]
  • [Cites] Br J Surg. 2003 Oct;90(10):1244-9 [14515294.001]
  • [Cites] Pancreatology. 2006;6(1-2):17-32 [16327281.001]
  • [Cites] Virchows Arch. 2006 Jul;449(1):112-6 [16639605.001]
  • [Cites] Gut. 2007 Aug;56(8):1086-90 [17127707.001]
  • [Cites] J Hepatobiliary Pancreat Surg. 2002;9(3):328-41 [12353144.001]
  • [Cites] Am J Surg Pathol. 2004 Jul;28(7):839-48 [15223952.001]
  • [Cites] J Pathol. 2002 Jun;197(2):201-10 [12015744.001]
  • [Cites] Hepatogastroenterology. 1999 Jan-Feb;46(25):483-91 [10228848.001]
  • [Cites] Ann Surg Oncol. 2008 Jan;15(1):199-205 [17909912.001]
  • [Cites] Pancreas. 1998 Apr;16(3):363-9 [9548680.001]
  • (PMID = 26190249.001).
  • [ISSN] 1865-7257
  • [Journal-full-title] Clinical journal of gastroenterology
  • [ISO-abbreviation] Clin J Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Keywords] NOTNLM ; Growth pattern / Intraductal papillary mucinous neoplasm / Mural nodule / Subtype
  •  go-up   go-down


58. Sanada Y, Oue N, Mitani Y, Yoshida K, Nakayama H, Yasui W: Down-regulation of the claudin-18 gene, identified through serial analysis of gene expression data analysis, in gastric cancer with an intestinal phenotype. J Pathol; 2006 Apr;208(5):633-42
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Down-regulation of the claudin-18 gene, identified through serial analysis of gene expression data analysis, in gastric cancer with an intestinal phenotype.
  • Gastric cancer (GC) is one of the most common malignancies worldwide.
  • Immunostaining showed that normal gastric mucosa and Paneth cells of the duodenum expressed claudin-18 on cell membranes.
  • Expression of claudin-18 was reduced in several intestinal metaplasias of the stomach.
  • Of 20 samples of gastric adenoma, 18 (90.0%) showed decreased claudin-18 expression.
  • In addition, expression of the gastric and intestinal phenotypes of GC was examined by immunostaining for MUC5AC, MUC6, MUC2, and CD10.
  • Down-regulation of claudin-18 may be involved in GCs with an intestinal phenotype, and may be an early event in gastric carcinogenesis.
  • [MeSH-major] Adenocarcinoma / metabolism. Biomarkers, Tumor / biosynthesis. Down-Regulation. Membrane Proteins / biosynthesis. Stomach Neoplasms / metabolism
  • [MeSH-minor] Claudins. Duodenum / metabolism. Gastric Mucosa / metabolism. Gene Expression Regulation, Neoplastic. Humans. Immunoenzyme Techniques. Neoplasm Proteins / biosynthesis. Neoplasm Proteins / genetics. Neoplasm Staging. Phenotype. RNA, Messenger / genetics. RNA, Neoplasm / genetics. Reverse Transcriptase Polymerase Chain Reaction / methods. Survival Analysis. Tumor Cells, Cultured

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16435283.001).
  • [ISSN] 0022-3417
  • [Journal-full-title] The Journal of pathology
  • [ISO-abbreviation] J. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CLDN18 protein, human; 0 / Claudins; 0 / Membrane Proteins; 0 / Neoplasm Proteins; 0 / RNA, Messenger; 0 / RNA, Neoplasm
  •  go-up   go-down


59. Jung MK, Jeon SW, Park SY, Cho CM, Tak WY, Kweon YO, Kim SK, Choi YH, Bae HI: Endoscopic characteristics of gastric adenomas suggesting carcinomatous transformation. Surg Endosc; 2008 Dec;22(12):2705-11
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic characteristics of gastric adenomas suggesting carcinomatous transformation.
  • BACKGROUND: Currently, endoscopic resections, including endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD), are widely performed for the management of gastric neoplasia.
  • Gastric adenoma was diagnosed initially for all the patients.
  • These variables were analyzed and compared between an adenoma group (51 cases) and a carcinoma group (63 cases) on the basis of postresection diagnosis.
  • The diameter of the lesions was 14.6 +/- 8.2 mm in the adenoma group and 15.4 +/- 7.4 mm in the carcinoma group.
  • Characteristics of gastric adenomas such as a depressed type, red color, and ulceration that may have foci of carcinomas in other parts of the adenomas also should be considered for endoscopic resection.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma / pathology. Cell Transformation, Neoplastic / pathology. Gastroscopy. Stomach Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biopsy. Diagnosis, Differential. Disease Progression. Dissection / methods. Female. Gastric Mucosa / pathology. Humans. Male. Middle Aged. Risk Factors. Stomach Ulcer / etiology. Stomach Ulcer / pathology

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Endoscopy. 2006 Oct;38(10):991-5 [17058163.001]
  • [Cites] Gastrointest Endosc. 1993 Jan-Feb;39(1):58-62 [8454147.001]
  • [Cites] Cancer. 1965 Jun;18:721-6 [14297468.001]
  • [Cites] Endoscopy. 2004 May;36(5):390-6 [15100945.001]
  • [Cites] Gut. 2000 Aug;47(2):251-5 [10896917.001]
  • [Cites] Cancer. 1990 May 1;65(9):2078-85 [2372773.001]
  • [Cites] Surg Clin North Am. 1989 Dec;69(6):1205-25 [2688151.001]
  • [Cites] Endoscopy. 2006 Oct;38(10):1001-6 [17058165.001]
  • [Cites] Surgery. 1956 Jan;39(1):114-9 [13298958.001]
  • [Cites] Cancer. 1971 Jun;27(6):1346-55 [5088211.001]
  • [Cites] Scand J Gastroenterol Suppl. 1990;178:7-12 [2277971.001]
  • [Cites] World J Gastroenterol. 2006 Jul 7;12(25):4029-32 [16810753.001]
  • [Cites] Semin Surg Oncol. 1994 Mar-Apr;10 (2):100-6 [8052776.001]
  • [Cites] J Gastroenterol Hepatol. 2007 Mar;22(3):311-4 [17295759.001]
  • [Cites] Hepatogastroenterology. 1998 Mar-Apr;45(20):579-82 [9638455.001]
  • [Cites] Clin Gastroenterol Hepatol. 2005 Jul;3(7 Suppl 1):S71-3 [16013003.001]
  • [Cites] Am J Gastroenterol. 1987 Oct;82(10):1016-25 [3661508.001]
  • [Cites] Endoscopy. 2006 Oct;38(10):987-90 [17058162.001]
  • [Cites] Am J Surg Pathol. 2006 Jan;30(1):114-8 [16330950.001]
  • [Cites] Endoscopy. 1993 Sep;25(7):445-50 [8261986.001]
  • [Cites] Curr Top Pathol. 1976;63:77-93 [795617.001]
  • [Cites] Endoscopy. 1993 May;25(4):261-4 [8330542.001]
  • [Cites] Gut. 2002 Apr;50(4):465-70 [11889063.001]
  • [Cites] J Clin Pathol. 1985 Jul;38(7):754-64 [4019798.001]
  • [Cites] Scand J Gastroenterol. 2006 Sep;41(9):1105-9 [16938725.001]
  • [Cites] Gastroenterology. 1994 Nov;107(5):1288-96 [7926493.001]
  • [Cites] Endoscopy. 2001 Jun;33(6):501-6 [11437043.001]
  • [Cites] J Gastroenterol. 2006 Apr;41(4):397-8 [16741625.001]
  • [Cites] Scand J Gastroenterol Suppl. 1979;54:104-5 [295493.001]
  • [Cites] Semin Diagn Pathol. 2002 Feb;19(1):20-30 [11936263.001]
  • [Cites] Endoscopy. 1978 Feb;10(1):63-5 [631098.001]
  • [Cites] Endoscopy. 1993 May;25(4):265-8 [8330543.001]
  • [Cites] Endoscopy. 1994 Oct;26(8):659-65 [7859674.001]
  • [Cites] Minerva Med. 1972 Oct 27;63(76):4145-7 [4634553.001]
  • [Cites] Intern Med. 2005 Feb;44(2):85-6 [15750264.001]
  • [Cites] J Gastroenterol. 2006 Oct;41(10):929-42 [17096062.001]
  • [Cites] Rev Gastroenterol Peru. 2005 Jan-Mar;25(1):76-92 [15818423.001]
  • [Cites] Intern Med. 2005 Oct;44(10):1033-8 [16293912.001]
  • [Cites] Endoscopy. 2003 Feb;35(2):118-26 [12561005.001]
  • [Cites] Cancer. 1982 Dec 1;50(11):2496-503 [7139542.001]
  • [Cites] Chin J Dig Dis. 2005;6(3):119-21 [16045601.001]
  • [Cites] Lancet. 1997 Jun 14;349(9067):1725-9 [9193382.001]
  • (PMID = 18401651.001).
  • [ISSN] 1432-2218
  • [Journal-full-title] Surgical endoscopy
  • [ISO-abbreviation] Surg Endosc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


60. Yoshida S, Tanaka S, Hirata M, Mouri R, Kaneko I, Oka S, Yoshihara M, Chayama K: Optical biopsy of GI lesions by reflectance-type laser-scanning confocal microscopy. Gastrointest Endosc; 2007 Jul;66(1):144-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Twenty-two areas of 15 untreated specimens from the esophagus (normal mucosa, n=1; dysplasia, n=1), stomach (normal mucosa, n=3; cancer, n=5), and colon (normal mucosa, n=3; adenoma, n=8; cancer, n=1) were examined.
  • Irregular nuclei were visualized in 3 of 5 gastric-cancer specimens and in cells around the crypt of the colonic-cancer specimen.
  • Nuclei were visualized in 5 of 8 colonic-adenoma specimens.
  • Nuclei were not visualized in 2 of 3 normal gastric-mucosa specimens or in normal colonic-mucosa specimens.
  • CONCLUSIONS: LCM provides instant microscopic images, and, with further technical improvement, in the future this novel method will aid in immediate diagnosis under endoscopy without the need for tissue biopsy.
  • [MeSH-major] Adenocarcinoma / pathology. Barrett Esophagus / pathology. Biopsy / methods. Colonic Neoplasms / pathology. Microscopy, Confocal. Stomach Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Biopsy.
  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Gastrointest Endosc. 2007 Jul;66(1):150-3 [17591489.001]
  • (PMID = 17591488.001).
  • [ISSN] 0016-5107
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Controlled Clinical Trial; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


61. Kikuchi S, Nemoto Y, Katada N, Sakuramoto S, Kobayashi N, Shimao H, Watanabe M: Results of follow-up endoscopy in patients who underwent proximal gastrectomy with jejunal interposition for gastric cancer. Hepatogastroenterology; 2007 Jan-Feb;54(73):304-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Results of follow-up endoscopy in patients who underwent proximal gastrectomy with jejunal interposition for gastric cancer.
  • BACKGROUND/AIMS: The present study evaluates the findings of long-term follow-up endoscopy in patients who underwent proximal gastrectomy with jejunal interposition for gastric cancer.
  • Tumors of the remnant stomach, early gastric cancer and gastric adenoma, were identified in 2 patients (3.6%) at 24 months and 69 months, respectively.
  • CONCLUSIONS: Jejunal interposition combined with proximal gastrectomy does not always prevent complications related to regurgitation of gastric content, and may not be a suitable treatment in view of postoperative endoscopic surveillance.
  • Further studies are required to identify an appropriate surgical approach to proximal gastrectomy for gastric cancer.
  • [MeSH-major] Endoscopy, Gastrointestinal. Gastrectomy / methods. Jejunum / transplantation. Stomach Neoplasms / surgery

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17419280.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  •  go-up   go-down


62. Yang MH, Son HJ, Lee JH, Kim MH, Kim JY, Kim YH, Chang DK, Rhee PL, Kim JJ, Rhee JC: Do we need colonoscopy in patients with gastric adenomas? The risk of colorectal adenoma in patients with gastric adenomas. Gastrointest Endosc; 2010 Apr;71(4):774-81
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Do we need colonoscopy in patients with gastric adenomas? The risk of colorectal adenoma in patients with gastric adenomas.
  • BACKGROUND: Gastric polyps are found frequently in various colonic polyposis syndromes.
  • Genetic alterations of several genes occur in gastric adenomas and colorectal adenomas.
  • However, it is unknown whether patients with gastric adenomas are at higher risk for colorectal adenomas.
  • OBJECTIVE: To investigate the prevalence rate of colorectal adenoma in patients with gastric adenomas and to determine the association between the presence of gastric adenomas and synchronous colorectal adenomas.
  • PATIENTS: This study involved 87 patients with gastric adenomas and 174 sex-matched and age-matched controls among 19,019 participants who underwent EGD and colonoscopy simultaneously or within 6 months of each other from January 2001 to December 2008 at the Center for Health Promotion of Samsung Medical Center.
  • MAIN OUTCOME MEASUREMENTS: The prevalence rate of colorectal adenoma in patients with gastric adenomas.
  • RESULTS: The 87 gastric adenoma patients included 72 men and 15 women.
  • The prevalence of colorectal adenoma was significantly higher in the gastric adenoma group than in the control group.
  • The majority of colorectal adenomas were located in distal colonic segments in the gastric adenoma group in contrast with proximal colonic segments in the control group.
  • Multivariate logistic regression analysis revealed that independent risk factors for colorectal adenoma were the presence of gastric adenomas (odds ratio [OR], .915; 95% confidence interval [CI], 1.044-3.513) and increasing age over 55 years (OR, 2.943; 95% CI, 1.558-5.560).
  • CONCLUSION: The risk of colorectal adenoma increases significantly in patients with gastric adenomas and in patients over age 55.
  • A screening colonoscopy may be necessary for patients with gastric adenomas to detect colorectal adenomas.
  • [MeSH-major] Adenoma / diagnosis. Colonoscopy. Colorectal Neoplasms / diagnosis. Gastroscopy. Neoplasms, Multiple Primary / diagnosis. Stomach Neoplasms / diagnosis

  • MedlinePlus Health Information. consumer health - Colonoscopy.
  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2010 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved.
  • (PMID = 20363417.001).
  • [ISSN] 1097-6779
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


63. Vallot T: [Gastric polyps]. Presse Med; 2007 Oct;36(10 Pt 2):1412-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Gastric polyps].
  • Gastric polyps exist in a wide variety of types, most often benign.
  • Endoscopic discovery of gastric polyps necessitates biopsies - not only of the lesion but also of the antral and fundic mucosa to determine the therapeutic strategy and subsequent surveillance.
  • These polyps are associated with an elevated frequency of precancerous alterations of the gastric mucosa and consequently by an elevated risk of synchronous or metachronous cancer.
  • Eradication of Helicobacter pylorus may reduce the risk of metachronous gastric cancer and recurrence after resection.
  • The advantages and procedures for endoscopic surveillance of patients with a precancerous condition of the gastric mucosa have not yet been clearly established in populations with a low incidence of cancer.
  • [MeSH-major] Adenocarcinoma. Adenoma. Carcinoid Tumor. Polyps. Precancerous Conditions. Stomach Diseases. Stomach Neoplasms
  • [MeSH-minor] Aged. Biopsy. Diagnosis, Differential. Endoscopy. Helicobacter Infections / complications. Helicobacter Infections / prevention & control. Helicobacter pylori. Humans. Incidence. Lymphatic Metastasis. Neoplasm Metastasis. Prevalence. Risk Factors. Stomach / pathology

  • MedlinePlus Health Information. consumer health - Carcinoid Tumors.
  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • MedlinePlus Health Information. consumer health - Stomach Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17482791.001).
  • [ISSN] 0755-4982
  • [Journal-full-title] Presse medicale (Paris, France : 1983)
  • [ISO-abbreviation] Presse Med
  • [Language] fre
  • [Publication-type] Comparative Study; English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 35
  •  go-up   go-down


64. Kimura T, Muguruma N, Ito S, Okamura S, Imoto Y, Miyamoto H, Kaji M, Kudo E: Infrared fluorescence endoscopy for the diagnosis of superficial gastric tumors. Gastrointest Endosc; 2007 Jul;66(1):37-43
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Infrared fluorescence endoscopy for the diagnosis of superficial gastric tumors.
  • We developed an IR fluorescence endoscope (IRFE) to observe superficial gastric tumors and assessed its clinical usefulness.
  • OBJECTIVE: To evaluate the clinical usefulness of an IRFE for the assessment of superficial gastric tumors.
  • PATIENTS: Thirty patients with gastric tumors were enrolled in this study, and their lesions were subjected to endoscopic submucosal dissection (ESD), or laparoscopic gastrectomy after observation with the IRFE.
  • METHODS: Gastric lesions were subjected to conventional observation, followed by IR fluorescence observation before and after intravenous ICG (0.01 mg/kg) injection.
  • RESULTS: Fluorescence was positive in 8 of 10 gastric cancers with submucosal invasion (80%) and 1 of 20 adenomas or intramucosal gastric cancers (5%); the difference was statistically significant (P<.01).
  • CONCLUSION: IRFE is a useful diagnostic tool for estimating the invasivity of gastric tumors.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma / pathology. Endoscopy, Gastrointestinal / methods. Fluorescence. Infrared Rays. Stomach Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • Hazardous Substances Data Bank. INDOCYANINE GREEN .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Gastrointest Endosc. 2008 Feb;67(2):386; author reply 386-7 [18226708.001]
  • (PMID = 17591472.001).
  • [ISSN] 0016-5107
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Coloring Agents; IX6J1063HV / Indocyanine Green
  •  go-up   go-down


65. Golger D, Probst A, Wagner T, Messmann H: Pyloric-gland adenoma of the stomach: case report of a rare tumor successfully treated with endoscopic submucosal dissection. Endoscopy; 2008 Sep;40 Suppl 2:E110-1
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pyloric-gland adenoma of the stomach: case report of a rare tumor successfully treated with endoscopic submucosal dissection.
  • [MeSH-major] Adenoma / surgery. Precancerous Conditions / surgery. Stomach Neoplasms / surgery
  • [MeSH-minor] Aged. Dissection. Female. Gastric Mucosa. Gastroscopy. Humans

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19085711.001).
  • [ISSN] 1438-8812
  • [Journal-full-title] Endoscopy
  • [ISO-abbreviation] Endoscopy
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


66. Köklü S, Başar O, Akbal E, Ibiş M: Gastric serrated adenoma polyp treated with endoscopic band ligation (with video). Surg Laparosc Endosc Percutan Tech; 2010 Dec;20(6):e204-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gastric serrated adenoma polyp treated with endoscopic band ligation (with video).
  • Serrated adenoma of the stomach has been very rarely reported.
  • A 34-year-old woman underwent upper gastrointestinal endoscopy showing a serrated adenoma polyp at the posterior wall of the junction of the fundus and body of the stomach.
  • At the follow-up, the base of the polyp was free of adenoma.
  • Beside several other polypectomy techniques, the band ligation technique may be used in removing of the gastric polyps, which is cheap, safe and technically easy to perform.
  • [MeSH-major] Adenoma / surgery. Stomach Neoplasms / surgery
  • [MeSH-minor] Adult. Female. Gastric Fundus. Humans. Ligation

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21150403.001).
  • [ISSN] 1534-4908
  • [Journal-full-title] Surgical laparoscopy, endoscopy & percutaneous techniques
  • [ISO-abbreviation] Surg Laparosc Endosc Percutan Tech
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Video-Audio Media
  • [Publication-country] United States
  •  go-up   go-down


67. Araki A, Shinohara M, Yamakawa J, Tanaka M, Natsui S, Izumi Y: Gastric diverticulum preoperatively diagnosed as one of two left adrenal adenomas. Int J Urol; 2006 Jan;13(1):64-6
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gastric diverticulum preoperatively diagnosed as one of two left adrenal adenomas.
  • Continued surgical exploration detected another mass between the spleen and the stomach, which was demonstrated to be continuous with the stomach and was eventually diagnosed as a gastric diverticulum.
  • [MeSH-major] Adrenocortical Adenoma / diagnosis. Diverticulum, Stomach / diagnosis. Preoperative Care
  • [MeSH-minor] Adrenalectomy / methods. Diagnosis, Differential. Humans. Hyperaldosteronism / diagnosis. Hyperaldosteronism / etiology. Laparoscopy. Male. Middle Aged. Tomography, X-Ray Computed

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16448434.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  •  go-up   go-down


68. Vieth M, Kushima R, Mukaisho K, Sakai R, Kasami T, Hattori T: Immunohistochemical analysis of pyloric gland adenomas using a series of Mucin 2, Mucin 5AC, Mucin 6, CD10, Ki67 and p53. Virchows Arch; 2010 Nov;457(5):529-36
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A pyloric gland adenoma (PGA) of the stomach was first described in a book chapter in 1976 by Kurt Elster and has been rarely reported in the literature.
  • A transition from gastric to intestinal differentiation can be observed focally as depicted by Mucin 2 and CD10 in 65% of the cases.
  • The gastric corpus mucosa of elderly patients with either Helicobacter pylori gastritis or autoimmune gastritis is highly affected.
  • The diagnosis of PGA can be confirmed immunohistochemically by staining against apomucin 6 and apomucin 5AC.
  • Focal intestinal differentiation supports the hypothesis that gastric adenocarcinomas can initially develop from carcinomas of the gastric type and transform into intestinal type later on.
  • [MeSH-major] Adenoma / metabolism. Biomarkers, Tumor / analysis. Gastric Mucosa / metabolism. Stomach Neoplasms / metabolism

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Int J Cancer. 1993 Dec 2;55(6):904-8 [8253526.001]
  • [Cites] Virchows Arch. 2000 Dec;437(6):581-90 [11193468.001]
  • [Cites] Am J Surg Pathol. 2009 Feb;33(2):186-93 [18830123.001]
  • [Cites] Virchows Arch. 1996 Jul;428(4-5):223-7 [8764930.001]
  • [Cites] Z Gastroenterol. 1989 Apr;27(4):212-7 [2543151.001]
  • [Cites] Pathologe. 1987 May;8(3):138-40 [3303008.001]
  • [Cites] Am J Surg Pathol. 1999 Feb;23(2):227-31 [9989851.001]
  • [Cites] Pathologe. 2001 Mar;22(2):97-104 [11321735.001]
  • [Cites] Virchows Arch. 2003 Apr;442(4):317-21 [12715167.001]
  • [Cites] Virchows Arch. 2002 Feb;440(2):205-8 [11964052.001]
  • [Cites] Pathol Int. 1996 May;46(5):333-40 [8809879.001]
  • [Cites] Virchows Arch. 1999 Oct;435(4):452-7 [10526011.001]
  • [Cites] Pathol Int. 1996 Nov;46(11):908-17 [8970203.001]
  • [Cites] Pathol Int. 2004 May;54(5):311-21 [15086835.001]
  • [Cites] Gynecol Oncol. 1999 Sep;74(3):504-11 [10479521.001]
  • [Cites] Virchows Arch. 2001 Jan;438(1):49-56 [11213835.001]
  • [Cites] Pathol Res Pract. 1996 Sep;192(9):963-9; discussion 970-1 [8950764.001]
  • [Cites] Pathologe. 2010 May;31(3):177-81 [20349063.001]
  • [Cites] Gastric Cancer. 2006;9(3):177-84 [16952035.001]
  • [Cites] Ultrastruct Pathol. 1999 Nov-Dec;23(6):375-81 [10626687.001]
  • (PMID = 20827489.001).
  • [ISSN] 1432-2307
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 0 / Mucin 5AC; 0 / Mucin-2; 0 / Tumor Suppressor Protein p53; EC 3.4.24.11 / Neprilysin
  •  go-up   go-down


69. Lee SY, Han HS, Lee KY, Hwang TS, Kim JH, Sung IK, Park HS, Jin CJ, Choi KW: Sonic hedgehog expression in gastric cancer and gastric adenoma. Oncol Rep; 2007 May;17(5):1051-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sonic hedgehog expression in gastric cancer and gastric adenoma.
  • Here, we analyzed the degree of hedgehog expression in gastric cancer and precancerous tissue.
  • From August 2005 to May 2006, 52 gastric cancers and 16 gastric adenomas were obtained from surgically or endoscopically resected specimens.
  • Although Shh expression was not related to the location, size, metastatic status, or mucin phenotype of the gastric cancer, the expression was stronger in the tubular type of gastric cancer than in the mucinous and signet-ring cell types (p=0.001).
  • Shh expression was stronger in gastric adenoma than in the diffuse-type gastric cancer (p<0.001), but revealed no difference with that of the intestinal-type gastric cancer (p=0.30).
  • Shh expression is related to the intestinal type of gastric cancer.
  • The stronger Shh expression in intestinal metaplasia and gastric adenoma indicates that hedgehog protein is involved at an early phase of gastric carcinogenesis.
  • [MeSH-major] Adenoma / metabolism. Hedgehog Proteins / biosynthesis. Stomach Neoplasms / metabolism

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17390043.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Hedgehog Proteins; 0 / SHH protein, human
  •  go-up   go-down


70. Nagano Y, Sekido H, Matsuoi K, Ohtsuki K, Gorai K, Kunisaki C, Ike H, Imada T, Shimada H: Successful pancreatoduodenectomy for carcinoma of the ampulla of vater after esophagectomy with remnant gastrectomy. Hepatogastroenterology; 2005 May-Jun;52(63):933-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In his past history, he had undergone distal gastrectomy for a gastric adenoma 17 years before.
  • [MeSH-major] Adenocarcinoma / surgery. Ampulla of Vater / surgery. Common Bile Duct Neoplasms / surgery. Esophageal Neoplasms / surgery. Esophagectomy. Gastrectomy. Gastric Stump / surgery. Neoplasms, Multiple Primary / surgery. Pancreaticoduodenectomy. Postoperative Complications / surgery
  • [MeSH-minor] Adenoma / surgery. Humans. Lymph Node Excision. Middle Aged. Neoplasm Invasiveness. Reoperation. Stomach Neoplasms / surgery

  • MedlinePlus Health Information. consumer health - After Surgery.
  • MedlinePlus Health Information. consumer health - Esophageal Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15966235.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  •  go-up   go-down


71. Lee SA, Choi SR, Jang JS, Lee JH, Roh MH, Kim SO, Kim MC, Kim SJ, Jeong JS: Expression of VEGF, EGFR, and IL-6 in gastric adenomas and adenocarcinomas by endoscopic submucosal dissection. Dig Dis Sci; 2010 Jul;55(7):1955-63
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of VEGF, EGFR, and IL-6 in gastric adenomas and adenocarcinomas by endoscopic submucosal dissection.
  • BACKGROUND: The degree of intratumoral microvascular density is thought to affect tumor metastasis and prognosis in various human cancers, including gastric cancer.
  • Despite recent medical advancements, gastric adenoma or adenocarcinoma remains a considerable therapeutic challenge.
  • Endoscopic submucosal dissection (ESD) is a more recent approach that is now commonly used for radical resection of gastric adenoma and adenocarcinoma.
  • AIM AND METHODS: The expression of vascular endothelial growth factor (VEGF), epidermal growth factor receptor (EGFR), and interleukin-6 (IL-6) are related to the prognosis of gastric adenocarcinoma.
  • However, the expression of these factors in gastric adenoma/adenocarcinoma following ESD has not been clearly evaluated.
  • Here, we report on our study of the expression of VEGF, EGFR, and IL-6 by immunohistochemical staining in extracted tissue from adenoma or adenocarcinoma of the stomach by ESD and subsequent evaluation of the correlation of VEGF, EGFR, and IL-6 with other clinicopathological parameters.
  • The patient cohort consisted of 102 patients with adenoma or adenocarcinoma of the stomach.
  • CONCLUSION: The immunohistochemical expression of IL-6 and VEGF can be considered to be useful for clinical diagnosis and follow-up of adenoma or adenocarcinoma of the stomach.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma / pathology. Interleukin-6 / metabolism. Receptor, Epidermal Growth Factor / metabolism. Stomach Neoplasms / pathology. Vascular Endothelial Growth Factor A / metabolism
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / analysis. Biomarkers, Tumor / metabolism. Biopsy, Needle. Cohort Studies. Female. Gastric Mucosa / pathology. Gastric Mucosa / surgery. Gastroscopy / methods. Humans. Immunohistochemistry. Male. Middle Aged. Prognosis. Sensitivity and Specificity

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Br J Cancer. 2004 Jan 12;90(1):206-15 [14710231.001]
  • [Cites] Virchows Arch. 2004 Apr;444(4):324-31 [14991403.001]
  • [Cites] J Gastroenterol Hepatol. 2002 Nov;17(11):1165-9 [12453275.001]
  • [Cites] J Pathol. 2000 Jul;191(3):239-44 [10878544.001]
  • [Cites] Mol Cancer Ther. 2007 Mar;6(3):1123-32 [17363505.001]
  • [Cites] Cancer Res. 1990 Mar 15;50(6):1774-8 [2155059.001]
  • [Cites] J Biomed Sci. 2004 Jul-Aug;11(4):517-27 [15153787.001]
  • [Cites] Histol Histopathol. 2000 Apr;15(2):455-62 [10809364.001]
  • [Cites] Cancer. 1999 Jun 1;85(11):2340-6 [10357403.001]
  • [Cites] World J Surg. 2007 Jul;31(7):1458-68 [17516110.001]
  • [Cites] Clin Gastroenterol Hepatol. 2003 Nov;1(6):438-45 [15017643.001]
  • [Cites] J Clin Oncol. 2005 Apr 10;23(11):2445-59 [15753456.001]
  • [Cites] J Clin Oncol. 2003 Jul 15;21(14):2787-99 [12860957.001]
  • [Cites] Cancer. 1996 Mar 1;77(5):858-63 [8608475.001]
  • [Cites] Endocr Rev. 1997 Feb;18(1):4-25 [9034784.001]
  • [Cites] Ann Surg Oncol. 2003 Apr;10(3):234-41 [12679307.001]
  • [Cites] Dig Liver Dis. 2008 Jul;40(7):504-9 [18486572.001]
  • [Cites] Clin Cancer Res. 1999 Jul;5(7):1823-9 [10430087.001]
  • [Cites] J Natl Cancer Inst. 1990 Jan 3;82(1):4-6 [1688381.001]
  • [Cites] Mod Pathol. 2004 May;17(5):579-87 [15073595.001]
  • [Cites] Am J Obstet Gynecol. 1991 Apr;164(4):1038-42; discussion 1042-3 [2014824.001]
  • [Cites] J Surg Oncol. 2006 Dec 1;94(7):624-30 [17111394.001]
  • [Cites] Oncology. 1995 May-Jun;52(3):182-8 [7715901.001]
  • [Cites] J Clin Invest. 1989 Dec;84(6):2008-11 [2592570.001]
  • [Cites] Cancer. 1997 Jan 15;79(2):206-13 [9010092.001]
  • [Cites] Blood. 1989 Sep;74(4):1360-7 [2788466.001]
  • [Cites] Lancet. 1994 Dec 3;344(8936):1576-7 [7983975.001]
  • [Cites] J Urol. 1992 Dec;148(6):1778-81; discussion 1781-2 [1433606.001]
  • [Cites] J Clin Invest. 1989 Nov;84(5):1470-8 [2478587.001]
  • [Cites] Cancer. 1997 Jul 1;80(1):98-106 [9210714.001]
  • [Cites] Jpn J Cancer Res. 1994 Oct;85(10):1045-9 [7525523.001]
  • [Cites] J Surg Oncol. 2001 Oct;78(2):132-7 [11579392.001]
  • [Cites] Immunol Today. 1990 Dec;11(12):443-9 [2127356.001]
  • [Cites] Clin Cancer Res. 1997 Jun;3(6):861-5 [9815760.001]
  • [Cites] Carcinogenesis. 2000 Jun;21(6):1111-5 [10836997.001]
  • [Cites] Anticancer Res. 2006 Sep-Oct;26(5A):3547-50 [17094480.001]
  • [Cites] Am J Gastroenterol. 1996 Jul;91(7):1417-22 [8678006.001]
  • [Cites] J Urol. 1992 Sep;148(3):791-4 [1512827.001]
  • [Cites] Dig Liver Dis. 2008 Aug;40(8):641-9 [18424243.001]
  • [Cites] Science. 1988 Aug 5;241(4866):708-12 [3041594.001]
  • (PMID = 19757047.001).
  • [ISSN] 1573-2568
  • [Journal-full-title] Digestive diseases and sciences
  • [ISO-abbreviation] Dig. Dis. Sci.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Interleukin-6; 0 / Vascular Endothelial Growth Factor A; EC 2.7.10.1 / Receptor, Epidermal Growth Factor
  •  go-up   go-down


72. Lee SH, Cheon JH, Kim JH, Park JP, Lee SK, Lee YC: [Non-healing iatrogenic gastric ulcers after endoscopic mucosal resection for gastric epithelial neoplasia: report of two cases]. Korean J Gastroenterol; 2008 Feb;51(2):127-31
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Non-healing iatrogenic gastric ulcers after endoscopic mucosal resection for gastric epithelial neoplasia: report of two cases].
  • Endoscopic mucosal resection (EMR) is widely accepted as a standard treatment for early gastric cancer or gastric adenoma.
  • Although the characteristics of EMR-induced ulceration are not fully understood, this type of ulcer is thought to heal faster and to recur less often than non-iatrogenic gastric ulcer.
  • Herein, we report two cases of non-healing persistent gastric ulcers after EMR.
  • One is a case of gastric carcinoma which developed at the same site of previous EMR site for the low grade dysplasia.
  • [MeSH-major] Gastric Mucosa / surgery. Stomach Neoplasms / surgery. Stomach Ulcer / etiology

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18349575.001).
  • [ISSN] 1598-9992
  • [Journal-full-title] The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
  • [ISO-abbreviation] Korean J Gastroenterol
  • [Language] kor
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Korea (South)
  •  go-up   go-down


73. Yoshida T, Kawachi H, Sasajima K, Shiokawa A, Kudo SE: The clinical meaning of a nonstructural pattern in early gastric cancer on magnifying endoscopy. Gastrointest Endosc; 2005 Jul;62(1):48-54
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The clinical meaning of a nonstructural pattern in early gastric cancer on magnifying endoscopy.
  • Since en bloc EMR was developed, differentiation between mucosal and submucosal cancer is a critical issue in the management of gastric cancer.
  • Compared with histologic findings, the clinical meaning of the presence of a nonstructural pattern on the gastric neoplastic lesion was evaluated.
  • CONCLUSIONS: The presence of a nonstructural pattern appeared to be a useful marker to not proceed with EMR of gastric cancer.
  • [MeSH-major] Adenoma / pathology. Gastroscopy / methods. Image Enhancement. Stomach Neoplasms / pathology
  • [MeSH-minor] Aged. Biopsy. Diagnosis, Differential. Female. Follow-Up Studies. Gastric Mucosa / pathology. Gastric Mucosa / surgery. Humans. Male. Middle Aged. Retrospective Studies

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15990819.001).
  • [ISSN] 0016-5107
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


74. Bajbouj M, von Weyhern C, Becker V, Seidl S, Ott R, Schatke W, Fend F, Schmid RM, Meining A: True adenomas of the cardia: a case series of 3 patients. Digestion; 2008;77(1):65-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS AND RESULTS: Three patients with polypoid masses at the cardia below the Z-line were submitted to a tertiary referral center for further diagnosis and therapy.
  • In 2 of the 3 cases the final histopathological diagnosis of low-grade adenoma of the cardia could only be established after complete removal of the polypoid masses.
  • CONCLUSIONS: Adenomas of the cardia can be mistaken for dysplasia arising from Barrett's esophagus, if the diagnosis is based on endoscopic biopsies only.
  • [MeSH-major] Adenomatous Polyps / pathology. Cardia / pathology. Stomach Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2008 S. Karger AG, Basel.
  • (PMID = 18349540.001).
  • [ISSN] 1421-9867
  • [Journal-full-title] Digestion
  • [ISO-abbreviation] Digestion
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
  •  go-up   go-down


75. Thomas D, Alexandraki K, Nikolaou A, Antoniou S, Kanakis G, Zilos A, Sougioultzis S, Kaltsas G: Primary hyperparathyroidism in patients with gastric carcinoid tumors type 1: an unusual coexistence. Neuroendocrinology; 2010;92(4):252-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary hyperparathyroidism in patients with gastric carcinoid tumors type 1: an unusual coexistence.
  • The aim of this study is to investigate the prevalence of PHP in our group of patients with gastric carcinoid (GC) type 1 tumors.
  • The diagnosis of PHP was suspected following elevated or high-normal serum calcium levels and elevated or inappropriate normal parathyroid hormone levels.
  • Four control groups were also studied: two age- and sex-matched groups of individuals with (n = 49) and without (n = 34) thyroid autoimmunity and normal endoscopy of the stomach, a third group with nongastric neuroendocrine tumors (n = 68), and a fourth group with atrophic gastritis and hypergastrinemia, without gastric endocrine tumors (n = 30).
  • Three of the 4 patients with PHP were operated and proved to have a parathyroid adenoma.
  • [MeSH-major] Carcinoid Tumor / complications. Hyperparathyroidism, Primary / complications. Stomach Neoplasms / complications
  • [MeSH-minor] Adenoma / complications. Adenoma / epidemiology. Adult. Aged. Aged, 80 and over. Case-Control Studies. Female. Humans. Incidence. Male. Middle Aged. Parathyroid Neoplasms / complications. Parathyroid Neoplasms / epidemiology. Retrospective Studies. Young Adult


76. Buffart TE, Carvalho B, Mons T, Reis RM, Moutinho C, Silva P, van Grieken NC, Vieth M, Stolte M, van de Velde CJ, Schrock E, Matthaei A, Ylstra B, Carneiro F, Meijer GA: DNA copy number profiles of gastric cancer precursor lesions. BMC Genomics; 2007;8:345
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] DNA copy number profiles of gastric cancer precursor lesions.
  • BACKGROUND: Chromosomal instability (CIN) is the most prevalent type of genomic instability in gastric tumours, but its role in malignant transformation of the gastric mucosa is still obscure.
  • In the present study, we set out to study whether two morphologically distinct categories of gastric cancer precursor lesions, i.e. intestinal-type and pyloric gland adenomas, would carry different patterns of DNA copy number changes, possibly reflecting distinct genetic pathways of gastric carcinogenesis in these two adenoma types.
  • The most frequent aberrations in intestinal-type gastric adenoma were gains on 11q, 9q and 8, and losses on chromosomes 5q, 6, 10 and 13, whereas in pyloric gland gastric adenomas these were gains on chromosome 20 and losses on 5q and 6.
  • However, no significant differences were observed between the two adenoma types.
  • CONCLUSION: The results suggest that gains on chromosomes 8, 9q, 11q and 20, and losses on chromosomes 5q, 6, 10 and 13, likely represent early events in gastric carcinogenesis.
  • [MeSH-major] DNA, Neoplasm / genetics. Precancerous Conditions / genetics. Stomach Neoplasms / genetics

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Cancer Genet Cytogenet. 2000 Mar;117(2):97-103 [10704677.001]
  • [Cites] Mol Pathol. 1999 Oct;52(5):243-51 [10748872.001]
  • [Cites] J Pathol. 2000 Nov;192(3):301-6 [11054712.001]
  • [Cites] Bioinformatics. 2000 Aug;16(8):685-98 [11099255.001]
  • [Cites] Genes Chromosomes Cancer. 2001 Jan;30(1):80-6 [11107179.001]
  • [Cites] Virchows Arch. 2000 Dec;437(6):581-90 [11193468.001]
  • [Cites] Am J Pathol. 2001 Feb;158(2):655-62 [11159202.001]
  • [Cites] Cytometry. 2001 Feb 15;46(1):57-62 [11241508.001]
  • [Cites] Am J Pathol. 2001 Jun;158(6):1961-7 [11395372.001]
  • [Cites] Nat Genet. 2001 Nov;29(3):263-4 [11687795.001]
  • [Cites] Genes Chromosomes Cancer. 2002 Nov;35(3):219-31 [12353264.001]
  • [Cites] Gastroenterology. 2002 Oct;123(4):1109-19 [12360473.001]
  • [Cites] Endoscopy. 1994 Oct;26(8):659-65 [7859674.001]
  • [Cites] Endoscopy. 1995 Jan;27(1):32-7; discussion 59-60 [7601032.001]
  • [Cites] Genes Chromosomes Cancer. 1995 Sep;14(1):28-34 [8527381.001]
  • [Cites] Gastrointest Endosc Clin N Am. 1997 Jan;7(1):29-46 [8995111.001]
  • [Cites] Eur J Cancer. 1997 Jun;33(7):1075-107 [9376190.001]
  • [Cites] Cancer Genet Cytogenet. 1998 Nov;107(1):32-6 [9809031.001]
  • [Cites] Nature. 1998 Dec 17;396(6712):643-9 [9872311.001]
  • [Cites] Br J Cancer. 1999 Jan;79(2):211-3 [9888459.001]
  • [Cites] Genes Chromosomes Cancer. 1999 Apr;24(4):299-305 [10092127.001]
  • [Cites] CA Cancer J Clin. 1999 Jan-Feb;49(1):33-64, 1 [10200776.001]
  • [Cites] Genes Chromosomes Cancer. 1999 Sep;26(1):29-34 [10441002.001]
  • [Cites] Virchows Arch. 1999 Oct;435(4):452-7 [10526011.001]
  • [Cites] Bioinformatics. 2004 Dec 12;20(18):3636-7 [15201182.001]
  • [Cites] Cell Oncol. 2004;26(5-6):307-17 [15623941.001]
  • [Cites] Cancer Sci. 2005 Feb;96(2):100-10 [15723654.001]
  • [Cites] Bioinformatics. 2005 Jul 15;21(14):3193-4 [15879450.001]
  • [Cites] J Pathol. 2007 Jan;211(1):45-51 [17117405.001]
  • [Cites] J Pathol. 2003 Feb;199(2):157-65 [12533828.001]
  • [Cites] Oncogene. 2003 Mar 27;22(12):1872-9 [12660823.001]
  • [Cites] Int J Oncol. 2003 May;22(5):1155-9 [12684685.001]
  • [Cites] Virchows Arch. 2003 Apr;442(4):317-21 [12715167.001]
  • [Cites] Virchows Arch. 2003 May;442(5):437-43 [12695913.001]
  • [Cites] Mol Pathol. 2003 Oct;56(5):293-8 [14514924.001]
  • [Cites] J Pathol. 2003 Nov;201(3):439-50 [14595756.001]
  • [Cites] Diagn Mol Pathol. 2003 Dec;12(4):193-200 [14639105.001]
  • [Cites] Mod Pathol. 2004 Nov;17(11):1328-37 [15154013.001]
  • [Cites] Lancet. 1975 Jul 12;2(7924):58-60 [49653.001]
  • (PMID = 17908304.001).
  • [ISSN] 1471-2164
  • [Journal-full-title] BMC genomics
  • [ISO-abbreviation] BMC Genomics
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DNA, Neoplasm
  • [Other-IDs] NLM/ PMC2147033
  •  go-up   go-down


77. Gutiérrez-Grobe Y, Gavilanes-Espinar JG, Uribe M, Kobashi-Margáin RA, Méndez-Sánchez N: Pyloric gland adenoma: case report. Rev Gastroenterol Mex; 2010;75(3):360-2
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pyloric gland adenoma: case report.
  • Pyloric gland adenoma (PGA), also called adenoma with gastric differentiation, is a rare neoplasm of the gastric mucosa that can appear as gastric heterotopia in several organs.
  • A 49-year-old woman presented with gastric reflux and chronic elevation of liver enzymes.
  • A few polyps were found and resected from the gastric fundus; histopathology revealed a pyloric gland adenoma.
  • [MeSH-major] Adenoma / pathology. Gastric Mucosa / pathology. Stomach Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20959193.001).
  • [ISSN] 0375-0906
  • [Journal-full-title] Revista de gastroenterología de México
  • [ISO-abbreviation] Rev Gastroenterol Mex
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Mexico
  • [Chemical-registry-number] 0 / MUC5AC protein, human; 0 / MUC6 protein, human; 0 / Mucin 5AC; 0 / Mucin-6
  •  go-up   go-down


78. Lee DS, Kang SB, Baek JT, Nam SW, Lee KM, Ahn BM, Lee EH, Han SW, Chung IS: [Immunohistochemical expression of bcl-2, bcl-xL, bax, p53 proteins in gastric adenoma and adenocarcinoma]. Korean J Gastroenterol; 2005 Jun;45(6):394-400
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Immunohistochemical expression of bcl-2, bcl-xL, bax, p53 proteins in gastric adenoma and adenocarcinoma].
  • BACKGROUND/AIMS: The aim of this study was to investigate the immunohistochemical expression of bcl-2, bcl-xL, bax, and p53 proteins according to the pathological parameters such as grade of dysplasia, histological type, depth of invasion, lymph node metastasis, and TNM stage in the gastric adenoma and gastric adenocarcinoma.
  • METHODS: Immunohistochemical staining using monoclonal bcl-2, bcl-xL, bax, p53 antibodies were performed on paraffin embedded specimens from forty-one gastric adenomas and 100 gastric adenocarcinomas.
  • CONCLUSIONS: Bcl-2 protein would be related with the development of gastric adenoma, especially with high grade dysplasia.
  • Bcl-xL and p53 proteins would be involved in the development of relatively early stage of gastric adenocarcinoma but not in tumor progression.
  • Bax protein would be involved in the development of gastric adenocarcinoma and related with depth of invasion, lymph node metastasis, and TNM stage.
  • [MeSH-major] Adenocarcinoma / metabolism. Adenoma / metabolism. Proto-Oncogene Proteins c-bcl-2 / metabolism. Stomach Neoplasms / metabolism. Tumor Suppressor Protein p53 / metabolism. bcl-2-Associated X Protein / metabolism. bcl-X Protein / metabolism

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15973073.001).
  • [ISSN] 1598-9992
  • [Journal-full-title] The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
  • [ISO-abbreviation] Korean J Gastroenterol
  • [Language] kor
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Korea (South)
  • [Chemical-registry-number] 0 / Proto-Oncogene Proteins c-bcl-2; 0 / Tumor Suppressor Protein p53; 0 / bcl-2-Associated X Protein; 0 / bcl-X Protein
  •  go-up   go-down


79. Zurac S, Micu G, Bastian A, Grămadă E, Lavric L, Andrei R, Stăniceanu F, Voiosu R, Croitoru A: Malignancy and overdiagnosis of malignancy in Peutz Jeghers polyposis. Rom J Intern Med; 2008;46(2):179-84
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Despite their benign nature there is a certain increased risk of progression to malignancy in some cases, justifying a sustained follow-up of the patients.
  • Two of these cases were related (mother and daughter); both of them were operated in another hospital for small bowel tumors with a subsequent diagnosis of adenocarcinoma.
  • The daughter (28 years old) was referred to our hospital for endoscopic follow-up; a small polyp of the transverse large bowel was excised by colonoscopy with a histopathologic diagnosis of PJ polyp; a careful histopathologic reevaluation of both specimens of enterectomy (slides and paraffin blocks) revealed an overdiagnosis of cancer due to the epithelial cystic dilatation and pseudoinvasion in both patients.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma / pathology. Intestinal Neoplasms / pathology. Intestinal Polyps / pathology. Peutz-Jeghers Syndrome / diagnosis. Stomach Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19284092.001).
  • [ISSN] 1220-4749
  • [Journal-full-title] Romanian journal of internal medicine = Revue roumaine de médecine interne
  • [ISO-abbreviation] Rom J Intern Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Romania
  •  go-up   go-down


80. Gheorghe C, Iacob R, Dumbrava M, Becheanu G, Ionescu M: Confocal laser endomicroscopy and ultrasound endoscopy during the same endoscopic session for diagnosis and staging of gastric neoplastic lesions. Chirurgia (Bucur); 2009 Jan-Feb;104(1):17-24
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Confocal laser endomicroscopy and ultrasound endoscopy during the same endoscopic session for diagnosis and staging of gastric neoplastic lesions.
  • We describe for the first time the use of both techniques during the same endoscopic session, in a pilot study, in order to increase the diagnostic yield of histological assessment and provide the staging of the gastric neoplastic lesions thus decreasing the time to therapeutic decision.
  • The indication of CLE/EUS exploration was the presence of a gastric polypoid lesion in 37% of cases, atypical gastric ulcer in 27% of patients, gastric lymphoma 18%, suspicion of gastric cancer recurrence after resection 9% and infiltrating type gastric cancer 9%.
  • Histological assessment after targeted biopsy has established the diagnosis of gastric adenocarcinoma in 55% of cases, gastric lymphoma in 18% of cases, gastric adenoma, gastric GIST and gastric foveolar hyperplasia in 9% of cases respectively.
  • In 2 patients - one case with suspected recurrent gastric cancer after surgery and one case of gastric lymphoma, CLE has indicated normal gastric mucosa.
  • The EUS evaluation showed in one gastric lymphoma patient a lesion interesting the mucosa and submucosa with regional adenopathy and a submucosal lesion with regional adenopathy in the other gastric lymphoma case.
  • [MeSH-major] Endosonography. Microscopy, Confocal. Stomach Neoplasms / pathology. Stomach Neoplasms / ultrasonography
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biopsy. Diagnosis, Differential. Female. Gastric Mucosa / pathology. Gastric Mucosa / ultrasonography. Humans. Male. Middle Aged. Neoplasm Staging. Pilot Projects. Reproducibility of Results. Sensitivity and Specificity

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19388564.001).
  • [ISSN] 1221-9118
  • [Journal-full-title] Chirurgia (Bucharest, Romania : 1990)
  • [ISO-abbreviation] Chirurgia (Bucur)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Romania
  •  go-up   go-down


81. Baba Y, Iyama K, Ikeda K, Ishikawa S, Hayashi N, Miyanari N, Honda Y, Sado Y, Ninomiya Y, Baba H: Differential expression of basement membrane type IV collagen alpha chains in gastric intramucosal neoplastic lesions. J Gastroenterol; 2007 Nov;42(11):874-80
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Differential expression of basement membrane type IV collagen alpha chains in gastric intramucosal neoplastic lesions.
  • BACKGROUND: The histological diagnosis of gastric intramucosal neoplastic lesions (GINLs) is controversial among experienced pathologists.
  • We examined the immunohistochemical expression of alpha(IV) chains in GINLs and investigated whether the expression pattern was a diagnostic marker of gastric intramucosal carcinoma.
  • RESULTS: In normal gastric epithelium, alpha1(IV), alpha2(IV), alpha5(IV), and alpha6(IV) chains were expressed continuously in the BM.
  • CONCLUSIONS: The loss of alpha5/alpha6(IV) chains might be a useful diagnostic finding for gastric intramucosal carcinoma in GINL cases.
  • [MeSH-major] Adenocarcinoma / metabolism. Basement Membrane / metabolism. Collagen Type IV / metabolism. Gastric Mucosa / metabolism. Stomach Neoplasms / metabolism
  • [MeSH-minor] Adenoma / diagnosis. Adenoma / metabolism. Adenoma / pathology. Epithelium / metabolism. Epithelium / pathology. Humans. Immunohistochemistry. Ki-67 Antigen / metabolism

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Biol Chem. 2000 Jul 14;275(28):21340-8 [10766752.001]
  • [Cites] Gastric Cancer. 2006;9(4):262-70 [17235627.001]
  • [Cites] Biochim Biophys Acta. 1990 Jun 1;1032(1):89-118 [1694687.001]
  • [Cites] Histochem Cell Biol. 1998 Oct;110(4):359-66 [9792414.001]
  • [Cites] Gastric Cancer. 2003;6(2):71-9 [12861397.001]
  • [Cites] J Gastroenterol Hepatol. 2002 Sep;17(9):980-6 [12167119.001]
  • [Cites] J Pathol. 2001 Aug;194(4):420-7 [11523049.001]
  • [Cites] Acta Pathol Microbiol Scand. 1965;64:31-49 [14320675.001]
  • [Cites] Lab Invest. 1999 Mar;79(3):281-92 [10092064.001]
  • [Cites] J Cell Biol. 1995 Sep;130(5):1219-29 [7657706.001]
  • [Cites] Biochem Biophys Res Commun. 2004 May 28;318(2):354-60 [15120609.001]
  • [Cites] Cancer. 1999 Oct 15;86(8):1449-54 [10526272.001]
  • [Cites] Am J Pathol. 2006 Mar;168(3):856-65 [16507901.001]
  • [Cites] Gastric Cancer. 2000 Dec;3(4):219-225 [11984739.001]
  • [Cites] J Biol Chem. 2000 Jan 14;275(2):1209-15 [10625665.001]
  • [Cites] Ann Surg. 2007 Jan;245(1):68-72 [17197967.001]
  • [Cites] Histopathology. 1998 Sep;33(3):197-202 [9777384.001]
  • [Cites] J Gastroenterol. 2006 Jun;41(6):547-53 [16868802.001]
  • [Cites] Gastric Cancer. 1998 Dec;1(1):10-24 [11957040.001]
  • [Cites] Lab Invest. 2001 Feb;81(2):167-75 [11232638.001]
  • [Cites] Gut. 1999 Jul;45 Suppl 1:I5-8 [10457028.001]
  • [Cites] Eur J Biochem. 1989 Apr 1;180(3):487-502 [2653817.001]
  • [Cites] Histochem J. 2002 Oct;34(10):479-86 [12945730.001]
  • [Cites] Exp Cell Res. 2004 Dec 10;301(2):251-65 [15530861.001]
  • [Cites] Histochem Cell Biol. 1995 Oct;104(4):267-75 [8548560.001]
  • [Cites] J Gastroenterol. 2006 Oct;41(10):929-42 [17096062.001]
  • [Cites] Pathol Int. 2002 Mar;52(3):224-33 [11972866.001]
  • [Cites] Dev Dyn. 1998 Jul;212(3):437-47 [9671947.001]
  • [Cites] J Biochem. 1998 May;123(5):767-76 [9562604.001]
  • [Cites] J Biol Chem. 1994 Sep 16;269(37):23013-7 [8083201.001]
  • [Cites] Cancer Res. 1991 Jul 1;51(13):3503-6 [2054789.001]
  • [Cites] Histochem J. 1997 Jul;29(7):563-70 [9279559.001]
  • [Cites] Virchows Arch. 2004 Jul;445(1):54-62 [15138813.001]
  • [Cites] Lab Invest. 1983 Dec;49(6):636-49 [6317982.001]
  • [Cites] Lancet. 1997 Jun 14;349(9067):1725-9 [9193382.001]
  • [Cites] Pathol Int. 2004 Jun;54(6):425-35 [15144402.001]
  • [Cites] J Biol Chem. 2000 Mar 17;275(11):8051-61 [10713126.001]
  • (PMID = 18008031.001).
  • [ISSN] 0944-1174
  • [Journal-full-title] Journal of gastroenterology
  • [ISO-abbreviation] J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Collagen Type IV; 0 / Ki-67 Antigen
  •  go-up   go-down


82. Yao T: [Clinicopathological features of small intestinal tumors]. Gan To Kagaku Ryoho; 2010 Aug;37(8):1436-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The prognosis of small intestinal cancer is poor, because preoperative diagnosis is difficult and it is usually discovered at the advanced stage.
  • In addition, it is thought that there are few small intestinal cancers of an adenoma origin, but dysplasia is considered to be associated with that complicated by Crohn's disease.
  • Among malignant lymphomas of the small intestine, the incidence of MALT lymphoma is lower, and those of T cell and follicular ones are higher than in the stomach.
  • Lymphomas with minimal cellular atypia are often encountered, and in such cases biopsy diagnosis is difficult.
  • The prognosis of malignant small intestinal disease will improve through early diagnosis with the recent progress in the procedures for detecting small intestinal disease.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20716865.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


83. Kimura M, Irie A, Minei S, Ishii J, Okawa A, Takashima R, Kadowaki K, Morinaga S, Baba S: [A case of adrenocortical adenoma coexisting with gastrointestinal stromal tumor]. Hinyokika Kiyo; 2007 Aug;53(8):551-5
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of adrenocortical adenoma coexisting with gastrointestinal stromal tumor].
  • A 48-year-old man was referred to our institute for the evaluation of a concomitant gastric submucosal tumor and right adrenal tumor, incidentally found by ultrasound examination.
  • Computed tomography showed a mass with a diameter of 6 cm adjacent to the stomach and the right adrenal tumor with a diameter of 3 cm.
  • On the other hand, the gastric submucosal tumor showed low intensity in T1 weighted images and high intensity in T2 weighted images.
  • Pathological diagnosis of the adrenal tumor was a cortical adenoma, and that of the gastric submucosal tumor was gastrointestinal stromal tumor (GIST).
  • The gastric tumor was immunohistochemically stained positive with the C-kit and CD34 and negative for s-100 protein and desmin.
  • Histopathological diagnosis was coincident with gastric GIST and right adrenocortical adenoma, and the GIST was diagnosed as a high risk tumor because its diameter was over 5 cm.
  • [MeSH-major] Adrenal Cortex Neoplasms / surgery. Adrenocortical Adenoma / surgery. Gastrointestinal Stromal Tumors / surgery. Laparoscopy. Stomach Neoplasms / surgery

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17874546.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


84. Tajima Y, Yamazaki K, Makino R, Nishino N, Aoki S, Kato M, Morohara K, Kaetsu T, Kusano M: Gastric and intestinal phenotypic marker expression in early differentiated-type tumors of the stomach: clinicopathologic significance and genetic background. Clin Cancer Res; 2006 Nov 1;12(21):6469-79
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gastric and intestinal phenotypic marker expression in early differentiated-type tumors of the stomach: clinicopathologic significance and genetic background.
  • PURPOSE: Gastric and intestinal phenotypic cell markers are expressed in gastric carcinomas, irrespective of their histologic type.
  • In the present study, we determined the clinicopathologic significance of phenotypic marker expression in early-stage gastric differentiated-type tumors and the association between marker expression and genetic alterations.
  • EXPERIMENTAL DESIGN: Phenotypic marker expression was determined by examining the expressions of human gastric mucin (HGM), MUC6, MUC2, and CD10 in 63 gastric adenomas, 133 early differentiated-type carcinomas, and 24 follow-up cases with gastric adenoma.
  • Tumors were classified into gastric, gastric and intestinal mixed, or intestinal phenotypes according to the immunopositivity of the above markers.
  • RESULTS: The expressions of HGM and MUC6, representing gastric or gastric and intestinal mixed phenotypes, were significantly associated with high-grade atypia in the 63 gastric adenomas.
  • A multivariate analysis revealed that gastric adenomas were significantly associated with the intestinal phenotype and were inversely associated with p53 mutation compared with early differentiated-type carcinomas.
  • Malignant transformation from gastric adenoma to carcinoma was shown in 5 of the 24 follow-up cases of gastric adenoma.
  • The malignant transformation was significantly associated with the gastric and intestinal mixed phenotype and was inversely associated with APC mutation.
  • No malignant transformation was found in intestinal phenotype gastric adenomas with APC mutation.
  • CONCLUSIONS: Our present findings show that phenotypic marker expression is associated with tumor aggressiveness during the early stage of gastric differentiated-type tumors.
  • Differences in the biological behavior of tumors with different phenotypes may result from differences in the genetic backgrounds during the incipient phase of gastric tumorigenesis.
  • [MeSH-major] Adenoma / genetics. Adenoma / metabolism. Biomarkers, Tumor / genetics. Stomach Neoplasms / genetics. Stomach Neoplasms / metabolism
  • [MeSH-minor] DNA Mutational Analysis. Gastric Mucins / biosynthesis. Genes, APC. Genes, p53. Genes, ras. Humans. Immunohistochemistry. Microsatellite Instability. Microsatellite Repeats. Mucin-2. Mucin-6. Mucins / biosynthesis. Mutation. Neprilysin / biosynthesis. Phenotype. Polymerase Chain Reaction

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17085661.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Gastric Mucins; 0 / MUC2 protein, human; 0 / MUC6 protein, human; 0 / Mucin-2; 0 / Mucin-6; 0 / Mucins; EC 3.4.24.11 / Neprilysin
  •  go-up   go-down


85. Srivastava A, Lauwers GY: Gastric epithelial dysplasia: the Western perspective. Dig Liver Dis; 2008 Aug;40(8):641-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gastric epithelial dysplasia: the Western perspective.
  • The need for early diagnosis of gastric cancer is emphasized by the fact that gastric cancer remains the second most common cause of cancer related deaths worldwide.
  • Most cases of gastric dysplasia have an "intestinal" phenotype referred to as adenomatous dysplasia.
  • A diagnosis of indefinite for dysplasia should also prompt endoscopic surveillance.
  • A diagnosis of high-grade dysplasia is more ominous, since it progress to cancer in most cases.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma / pathology. Gastric Mucosa / pathology. Precancerous Conditions / pathology. Stomach Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18424243.001).
  • [ISSN] 1878-3562
  • [Journal-full-title] Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
  • [ISO-abbreviation] Dig Liver Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  •  go-up   go-down


86. Park DI, Park SH, Yoo TW, Kim HS, Yang SK, Byeon JS, Koh BM, Kim JO, Shim KN, Jeen YT, Lee BI, Choi KY, Lee HL, Han DS, Baek I, Park CH, Park SJ: The prevalence of colorectal neoplasia in patients with gastric cancer: a Korean Association for the Study of Intestinal Disease (KASID) Study. J Clin Gastroenterol; 2010 Feb;44(2):102-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The prevalence of colorectal neoplasia in patients with gastric cancer: a Korean Association for the Study of Intestinal Disease (KASID) Study.
  • GOALS: The goal of this study was to determine the prevalence of colorectal neoplasia, using colonoscopy surveillance, in a cohort of patients with gastric cancers.
  • BACKGROUND: The association between gastric cancer and colorectal cancer has been conflicting.
  • STUDY: A total of 543 patients (males, 362; females, 181) with gastric cancer were matched with 2 persons from the population without a diagnosis of gastric cancer as confirmed by endoscopy according to age (+/-2 y), sex, date of colonoscopy examination (+/-2 wk), and endoscopist.
  • RESULTS: A significantly higher colorectal cancer prevalence was found in the gastric cancer group, that is, 19 of 543 (3.5%) versus 14 of 1086 (1.3%; P<0.001).
  • The odds of developing colorectal cancer were higher in the presence of gastric cancer (odds ratios, 3.46; 95% confidence interval: 1.51-7.91).
  • Four of the 119 (3.4%) gastric cancer patients below 50 years of age had colorectal cancer in contrast with no cases in the matched controls.
  • The prevalence of colorectal adenoma was higher in the gastric cancer group, with a prevalence of 215 in 543 (39.6%) versus 311 in 1086 (28.6%; P<0.001).
  • The risk of adenoma was also greater among gastric cancer patients (odds ratios, 1.76; 95% confidence interval: 1.34-2.25).
  • CONCLUSIONS: Our data reveal a higher prevalence and risk of colorectal cancer in patients diagnosed with gastric cancer, particularly in patients below 50 years of age.
  • Additional studies are needed to explore the geographical differences in the association between gastric cancer and colon cancer.
  • [MeSH-major] Adenoma / epidemiology. Colorectal Neoplasms / epidemiology. Stomach Neoplasms / pathology


87. Lindtner RA, Schreiber F, Langner C: Cytokeratin 7 immunostaining facilitates recognition of pancreatic heterotopia in gastric biopsies. Pathol Int; 2007 Aug;57(8):548-50
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytokeratin 7 immunostaining facilitates recognition of pancreatic heterotopia in gastric biopsies.
  • [MeSH-major] Choristoma / metabolism. Keratin-7 / metabolism. Pancreas. Stomach Diseases / metabolism
  • [MeSH-minor] Adenocarcinoma / pathology. Adenoma / pathology. Aged. Biopsy. Diagnosis, Differential. Gastrointestinal Stromal Tumors / pathology. Humans. Male. Middle Aged. Neoplasm Metastasis / pathology. Stomach Neoplasms / pathology. Stomach Neoplasms / secondary

  • MedlinePlus Health Information. consumer health - Stomach Disorders.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17610481.001).
  • [ISSN] 1320-5463
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Letter
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Keratin-7
  •  go-up   go-down


88. Yu JY: [Pathologic diagnosis and clinical significance of gastrointestinal epithelial dysplasia in biopsy specimens]. Zhonghua Bing Li Xue Za Zhi; 2009 Feb;38(2):77-80
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pathologic diagnosis and clinical significance of gastrointestinal epithelial dysplasia in biopsy specimens].
  • [MeSH-major] Colorectal Neoplasms / diagnosis. Gastric Mucosa / pathology. Intestinal Mucosa / pathology. Precancerous Conditions / diagnosis. Stomach Neoplasms / diagnosis
  • [MeSH-minor] Adenoma / pathology. Biopsy. Carcinoma in Situ / pathology. Cell Transformation, Neoplastic. Colitis, Ulcerative / pathology. Crohn Disease / pathology. Humans

  • MedlinePlus Health Information. consumer health - Colorectal Cancer.
  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19573349.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] Journal Article
  • [Publication-country] China
  •  go-up   go-down


89. Ogata M, Maejima K, Chihara N, Mizutani S, Komine O, Bo H, Shioya T, Watanabe M, Tokunaga A, Tajiri T: Successful use of endoscopic argon plasma coagulation for patients with early gastric cancer and diabetes mellitus. J Nippon Med Sch; 2007 Jun;74(3):246-50
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Successful use of endoscopic argon plasma coagulation for patients with early gastric cancer and diabetes mellitus.
  • We report on two patients with gastric tumors (early cancer and adema) and diabetes mellitus who were treated with argon plasma coagulation (APC) therapy. Case 1.
  • An early gastric cancer (IIc) in the anterior wall of the gastric antrum was diagnosed on the basis of the results of a gastric endoscopy examination.
  • A 61-year-old man was referred to our hospital because of a gastric tumor.
  • A gastric adenoma in the anterior of the gastric antrum was diagnosed on the basis of the results of a gastric endoscopy examination.
  • Endoscopic APC was performed in both patients to remove the gastric tumors.
  • APC therapy appears to be a safe and useful treatment for patients with diabetes and gastric mucosal lesions.
  • [MeSH-major] Diabetes Complications. Gastroscopy. Laser Coagulation / methods. Stomach Neoplasms / surgery
  • [MeSH-minor] Adenoma / surgery. Aged. Argon. Female. Humans. Male. Middle Aged

  • Genetic Alliance. consumer health - Diabetes.
  • MedlinePlus Health Information. consumer health - Diabetes Complications.
  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • Hazardous Substances Data Bank. Argon, Elemental .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17625375.001).
  • [ISSN] 1345-4676
  • [Journal-full-title] Journal of Nippon Medical School = Nippon Ika Daigaku zasshi
  • [ISO-abbreviation] J Nippon Med Sch
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 67XQY1V3KH / Argon
  •  go-up   go-down


90. Zheng H, Takahashi H, Murai Y, Cui Z, Nomoto K, Tsuneyama K, Takano Y: Low expression of FHIT and PTEN correlates with malignancy of gastric carcinomas: tissue-array findings. Appl Immunohistochem Mol Morphol; 2007 Dec;15(4):432-40
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Low expression of FHIT and PTEN correlates with malignancy of gastric carcinomas: tissue-array findings.
  • To clarify the roles of FHIT (fragile histidine triad) and PTEN (phosphatase and tensin homology deleted from human chromosome 10) expression in the genesis and progression of gastric cancers, we examined expression of FHIT and PTEN on tissue microarray containing gastric normal mucosa (n=49), adenoma (n=49), noncancerous mucosa adjacent to carcinoma (n=84) and carcinoma (n=249) by immunohistochemistry.
  • The results showed expression of FHIT and PTEN were lower in gastric carcinoma than those in normal mucosa, noncancerous mucosa adjacent to carcinoma and adenoma of the stomach (P<0.05).
  • FHIT and PTEN expression showed a significantly negative association with depth of invasion, lymphatic invasion, and lymph node metastasis, liver metastasis, and Union Internationale Contre le Cancer staging of gastric carcinoma (P<0.05).
  • Intestinal-type gastric carcinomas highly expressed FHIT and PTEN protein, compared with diffuse-type ones (P<0.05).
  • Expression of FHIT and PTEN were positively related with expression of p53 and cysteine protease protein 32 in gastric carcinoma (P<0.05), as well as favorable prognosis of the patients with the tumors (P<0.05).
  • There was positive relationship between FHIT and PTEN expression in gastric carcinoma (P<0.05).
  • It was suggested that down-regulated expression of FHIT and PTEN contributed to gastric carcinogenesis possibly by involving in the imbalance between apoptosis and proliferation of cells.
  • Their altered expression underlay the molecular basis of invasion, metastasis, differentiation of gastric carcinoma.

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18091387.001).
  • [ISSN] 1541-2016
  • [Journal-full-title] Applied immunohistochemistry & molecular morphology : AIMM
  • [ISO-abbreviation] Appl. Immunohistochem. Mol. Morphol.
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Neoplasm Proteins; 0 / fragile histidine triad protein; EC 3.1.3.48 / PTEN protein, human; EC 3.1.3.67 / PTEN Phosphohydrolase; EC 3.6.- / Acid Anhydride Hydrolases
  •  go-up   go-down


91. Kristick KL, Ranck RS, Fink M: What is your diagnosis? Biliary cystadenoma of the liver causing deviation of the stomach to the left. J Am Vet Med Assoc; 2010 May 15;236(10):1065-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] What is your diagnosis? Biliary cystadenoma of the liver causing deviation of the stomach to the left.
  • [MeSH-major] Adenoma, Bile Duct / veterinary. Bile Duct Neoplasms / veterinary. Bile Ducts, Intrahepatic. Cat Diseases / radiography. Stomach / radiography
  • [MeSH-minor] Animals. Cats. Diagnosis, Differential. Male

  • MedlinePlus Health Information. consumer health - Bile Duct Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20470066.001).
  • [ISSN] 0003-1488
  • [Journal-full-title] Journal of the American Veterinary Medical Association
  • [ISO-abbreviation] J. Am. Vet. Med. Assoc.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


92. Park SY, Yoo EJ, Cho NY, Kim N, Kang GH: Comparison of CpG island hypermethylation and repetitive DNA hypomethylation in premalignant stages of gastric cancer, stratified for Helicobacter pylori infection. J Pathol; 2009 Dec;219(4):410-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comparison of CpG island hypermethylation and repetitive DNA hypomethylation in premalignant stages of gastric cancer, stratified for Helicobacter pylori infection.
  • CpG island hypermethylation and genomic DNA hypomethylation are found not only in gastric cancers but also in associated premalignant lesions.
  • Helicobacter pylori infection induces aberrant CpG island hypermethylation in gastric mucosae.
  • The present study characterized methylation changes in a subset of genes and repetitive DNA elements (ALU, LINE-1, SAT2) and examined their relationship with H. pylori infection in premalignant lesions of gastric cancers.
  • We performed MethyLight analysis of 25 genes and SAT2 and COBRA analysis of ALU and LINE-1 in 212 gastric tissue samples. H. pylori infection was closely associated with enhanced hypermethylation of CpG island loci in chronic gastritis samples, but this association was not found among intestinal metaplasias, gastric adenomas and gastric cancers.
  • The number of methylated genes was greater in intestinal metaplasia and gastric adenoma samples than in chronic gastritis samples, regardless of H. pylori infection.
  • Methylation of repetitive DNA elements in gastric lesions generally decreased with progression of the gastric lesion along the multistep carcinogenesis.
  • No difference was noted in the number of methylated genes in chronic gastritis or intestinal metaplasia between gastric cancer patients and non-cancer subjects.
  • In conclusion, we found that there was no enhanced CpG island hypermethylation in gastric cancer and premalignant lesions in association with H. pylori infection and our findings suggest that CpG island hypermethylation and repetitive DNA hypomethylation are enhanced with progression of the gastric lesion through the multistep carcinogenesis, regardless of the status of H. pylori infection.
  • [MeSH-major] CpG Islands / genetics. DNA Methylation / genetics. DNA, Neoplasm / genetics. Precancerous Conditions / genetics. Stomach Neoplasms / genetics
  • [MeSH-minor] Adenoma / genetics. Adenoma / microbiology. Cell Transformation, Neoplastic / genetics. Chronic Disease. Disease Progression. Female. Gastric Mucosa / pathology. Gastritis / genetics. Gastritis / microbiology. Helicobacter Infections / complications. Helicobacter Infections / genetics. Helicobacter pylori. Humans. Male. Metaplasia / genetics. Metaplasia / microbiology

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19639607.001).
  • [ISSN] 1096-9896
  • [Journal-full-title] The Journal of pathology
  • [ISO-abbreviation] J. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DNA, Neoplasm
  •  go-up   go-down


93. Noji S, Takayanagi K: A case of laughter therapy that helped improve advanced gastric cancer. Jpn Hosp; 2010 Jul;(29):59-64
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of laughter therapy that helped improve advanced gastric cancer.
  • We have reported the case of a patient diagnosed as having advanced gastric cancer at the age of 88 years old.
  • An endoscopy revealed a type-2 gastric cancer of 25 x 30 mm in the lesser curvature of the middle stomach body and an IIa gastric cancer with T2 SS and cardiac accessory lesions.
  • One year and seven months later, an endoscopy of the lesser curvature of the middle stomach body indicated that the lesions clearly improved with a morphological reduction into IIa + IIc masses.
  • A tissue biopsy revealed that nucleus abnormality clearly improved from the initial diagnosis, with no irregularity in size.
  • The suspected lesion was localized to a limited area near the stomach wall.
  • Although partial gastric adenocarcinoma was suspected, the cancers turned into gastric adenoma, atrophic gastritis, and enteroepithelium metaplastic carcinoma.
  • Now, five years after the initial diagnosis, she maintains a good condition.
  • [MeSH-major] Laughter Therapy. Stomach Neoplasms

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21706962.001).
  • [ISSN] 0910-1004
  • [Journal-full-title] Japan-hospitals : the journal of the Japan Hospital Association
  • [ISO-abbreviation] Jpn Hosp
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


94. Sargan I, Motoc A, Vaida MA, Bolintineanu S: Benign gastric tumors. Anatomopathological aspects of the gastric wall. Rev Med Chir Soc Med Nat Iasi; 2007 Oct-Dec;111(4):996-1000
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign gastric tumors. Anatomopathological aspects of the gastric wall.
  • Benign tumours of the stomach are quite rare and are discovered accidentally during routine endoscopy or necroscopy.
  • They represent less than 20 per cent of gastric tumours, and their clinical picture consists in pain, bleeding and antropyloric stenosis.
  • RESULTS: Benign tumoural pathology was present in 73 cases, 43 (58.9%) in women, 30 (42.1%) in men.
  • The material for study consisted in gastric resection pieces and specimens of needle biopsy.
  • In order to establish the histopathological diagnosis and to define the specific type of the damage, the first specimens were stained using morphological methods.
  • [MeSH-major] Biopsy, Needle. Precancerous Conditions / pathology. Stomach Neoplasms / pathology
  • [MeSH-minor] Adenoma / pathology. Adult. Aged. Aged, 80 and over. Cardia / pathology. Diagnosis, Differential. Female. Hemangioma / pathology. Hospitals, General. Humans. Leiomyoma / pathology. Male. Middle Aged. Neurilemmoma / pathology. Polyps / pathology. Pyloric Antrum / pathology. Retrospective Studies. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18389794.001).
  • [ISSN] 0048-7848
  • [Journal-full-title] Revista medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti din Iaş̧i
  • [ISO-abbreviation] Rev Med Chir Soc Med Nat Iasi
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Romania
  •  go-up   go-down


95. Kim SG, Song HJ, Choi IJ, Cho JY, Jung HY, Keum B, Cheon JH, Lee YC, Kim JG, Park SK, Park BJ, Jung HC, Korean College of Helicobacter and Upper Gastrointestinal Research: A Planned Prospective, Randomized, Placebo-Controlled Multicenter Trial Assessing the Effect of Helicobacter pylori Eradication on the Healing of Iatrogenic Ulcer after Endoscopic Resection of Gastric Neoplasm. Gut Liver; 2010 Dec;4(4):514-7
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A Planned Prospective, Randomized, Placebo-Controlled Multicenter Trial Assessing the Effect of Helicobacter pylori Eradication on the Healing of Iatrogenic Ulcer after Endoscopic Resection of Gastric Neoplasm.
  • BACKGROUND/AIMS: Helicobacter pylori eradication may facilitate the healing of iatrogenic ulcer after endoscopic resection of gastric neoplasm.
  • METHODS: We intend to enroll up to 232 patients H.-pylori-positive patients who have gastric adenoma or early gastric cancer after endoscopic resection.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] N Engl J Med. 2001 Sep 13;345(11):784-9 [11556297.001]
  • [Cites] J Gastroenterol Hepatol. 2001 Nov;16(11):1211-6 [11903737.001]
  • [Cites] Gastrointest Endosc. 2003 Apr;57(4):567-79 [12665775.001]
  • [Cites] Aliment Pharmacol Ther. 2006 Sep 1;24(5):837-43 [16918888.001]
  • [Cites] J Gastroenterol Hepatol. 2006 Oct;21(10):1586-9 [16928221.001]
  • [Cites] Am J Gastroenterol. 2003 Oct;98(10):2149-56 [14572560.001]
  • [Cites] Gastrointest Endosc. 2004 Aug;60(2):213-7 [15278047.001]
  • [Cites] Aliment Pharmacol Ther. 2005 Jun;21 Suppl 2:111-5 [15943857.001]
  • [Cites] J Clin Gastroenterol. 2006 Apr;40(4):293-6 [16633099.001]
  • [Cites] Helicobacter. 2008 Dec;13(6):564-71 [19166423.001]
  • (PMID = 21253301.001).
  • [ISSN] 2005-1212
  • [Journal-full-title] Gut and liver
  • [ISO-abbreviation] Gut Liver
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC3021608
  • [Keywords] NOTNLM ; Endoscopic resection / Eradication / Helicobacter pylori / Iatrogenic ulcer / Medical Research Collaboration Center
  •  go-up   go-down


96. Lee JM, Lee HW, Hong YS, Kim ES, Park KS, Cho KB, Hwang JS, Kim HS: [A case of acute myocardial infarction occurred immediately after endoscopic submucosal dissection]. Korean J Gastroenterol; 2010 Oct;56(4):249-54
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Endoscopic methods such as endoscopic mucosal resection or endoscopic submucosal dissection (ESD) have been increasingly used for the treatment of gastric adenoma and early gastric cancer.
  • [MeSH-major] Dissection / adverse effects. Myocardial Infarction / diagnosis
  • [MeSH-minor] Acute Disease. Adenoma / surgery. Aged. Coronary Angiography. Endoscopy, Gastrointestinal. Female. Gastric Mucosa / surgery. Humans. Stomach Neoplasms / surgery

  • MedlinePlus Health Information. consumer health - Heart Attack.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20962561.001).
  • [ISSN] 1598-9992
  • [Journal-full-title] The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
  • [ISO-abbreviation] Korean J Gastroenterol
  • [Language] kor
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  •  go-up   go-down


97. Vieth M, Vogel C, Kushima R, Borchard F, Stolte M: Pyloric gland adenoma-- how to diagnose? Cesk Patol; 2006 Jan;42(1):4-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pyloric gland adenoma-- how to diagnose?
  • The term "pyloric gland adenoma" reflects its etiogenesis from deep mucoid glands in the stomach.
  • The diagnosis can be confirmed by immunohistochemistry.
  • Typically, pyloric gland adenomas are strongly positive for Mucin 6 (deep mucoid gastric glands).
  • Combination or transdifferentiation with ordinary tubular (intestinal differentiation) adenoma can be observed.
  • The gastric corpus mucosa of elderly female patients with autoimmune gastritis is highly affected.
  • The frequency of pyloric gland adenoma is given in the literature being 2.7% of all gastric polyps.
  • Pyloric gland adenomas can arise in gastric heterotopia and gastric metaplasia in the whole gastrointestinal tract.
  • [MeSH-major] Adenoma / diagnosis. Gastric Mucosa. Stomach Neoplasms / diagnosis

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16506593.001).
  • [ISSN] 1210-7875
  • [Journal-full-title] Československá patologie
  • [ISO-abbreviation] Cesk Patol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Czech Republic
  • [Chemical-registry-number] 0 / Mucins
  • [Number-of-references] 24
  •  go-up   go-down


98. Cho YG, Song JH, Kim CJ, Nam SW, Yoo NJ, Lee JY, Park WS: Genetic and epigenetic analysis of the KLF4 gene in gastric cancer. APMIS; 2007 Jul;115(7):802-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Genetic and epigenetic analysis of the KLF4 gene in gastric cancer.
  • In this study, the molecular basis of the KLF4 inactivation in gastric cancer was investigated by analyzing the somatic mutation, the allelic loss with two microsatellite markers, D9S53 and D9S105, and hypermethylation of the KLF4 gene in 47 gastric adenomas and 81 gastric adenocarcinomas.
  • Mutational analysis revealed one mutation of the KLF4 gene in a diffuse-type advanced gastric adenocarcinoma, but not in the gastric adenoma.
  • An allelic loss was found in 7 (22.6%) of the 31 informative gastric adenoma cases and 15 (31.3%) of the 48 informative cancer cases at one or both markers.
  • In addition, promoter hypermethylation of the KLF4 gene was observed in only two gastric cancers.
  • These results suggest that genetic and epigenetic alterations of the KLF4 gene might play a minor role in gastric carcinogenesis.
  • [MeSH-major] Adenocarcinoma / genetics. Epigenesis, Genetic. Gene Expression Regulation. Kruppel-Like Transcription Factors / genetics. Stomach Neoplasms / genetics

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17614846.001).
  • [ISSN] 0903-4641
  • [Journal-full-title] APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
  • [ISO-abbreviation] APMIS
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / GKLF protein; 0 / Kruppel-Like Transcription Factors
  •  go-up   go-down


99. Lee KM, Kim YB, Sin SJ, Jung JY, Hwang JC, Lim SG, Yoo BM, Kim JH, Cho SW: Argon plasma coagulation with submucosal saline injection for gastric adenoma on outpatient basis. Dig Dis Sci; 2009 Dec;54(12):2623-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Argon plasma coagulation with submucosal saline injection for gastric adenoma on outpatient basis.
  • Gastric adenoma with low-grade dysplasia (LGD) is a less progressive disease than with high-grade dysplasia; nevertheless, a certain portion of lesions can progress.
  • The purpose of this study was to evaluate the effectiveness of argon plasma coagulation (APC) with submucosa saline injections (APC-SSI) for gastric adenoma with LGD on an outpatient department (OPD) basis.
  • We included 57 patients with 64 lesions of gastric adenoma with LGD.
  • Twelve lesions were adenoma with LGD and two lesions were intramucosal adenocarcinoma.
  • APC-SSI is an effective and safe treatment modality for gastric adenoma with LGD on an OPD basis and it is recommended for patients with risk factors of endoscopic mucosal resection (EMR).
  • After treatment of gastric adenoma, meticulous follow-up endoscopy is recommended for detection of metachronous lesions.
  • [MeSH-major] Adenoma / therapy. Ambulatory Care. Argon Plasma Coagulation. Gastric Mucosa / surgery. Sodium Chloride / administration & dosage. Stomach Neoplasms / therapy

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • Hazardous Substances Data Bank. SODIUM CHLORIDE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] © Springer Science+Business Media, LLC 2008
  • [Cites] Gut. 2003 Mar;52(3):334-9 [12584212.001]
  • [Cites] Endoscopy. 1997 Mar;29(3):176-81 [9201466.001]
  • [Cites] Gastrointest Endosc. 2005 Dec;62(6):963-9 [16301045.001]
  • [Cites] Gastrointest Endosc. 2006 Jan;63(1):48-54 [16377315.001]
  • [Cites] Gastrointest Endosc. 2003 Apr;57(4):455-61 [12665753.001]
  • [Cites] Endoscopy. 2000 Oct;32(10):773-8 [11068836.001]
  • [Cites] Hepatogastroenterology. 1997 Nov-Dec;44(18):1602-11 [9427030.001]
  • [Cites] Gastrointest Endosc. 2000 Sep;52(3):342-5 [10968847.001]
  • [Cites] Gut. 1999 Nov;45(5):784-90 [10517922.001]
  • [Cites] Am J Gastroenterol. 1993 Oct;88(10):1714-9 [8213713.001]
  • [Cites] Gastrointest Endosc. 2006 May;63(6):776-82 [16650537.001]
  • [Cites] Hepatogastroenterology. 2004 Nov-Dec;51(60):1658-61 [15532798.001]
  • [Cites] Gastroenterology. 1994 Nov;107(5):1288-96 [7926493.001]
  • [Cites] Gastrointest Endosc. 2002 Oct;56(4):467-71 [12297759.001]
  • [Cites] Endoscopy. 2004 Jul;36(7):579-83 [15243878.001]
  • [Cites] J Clin Pathol. 1980 Aug;33(8):711-21 [7430384.001]
  • [Cites] Endoscopy. 1999 Nov;31(9):698-701 [10604609.001]
  • [Cites] Gut. 1990 Sep;31(9):977-83 [2210465.001]
  • [Cites] Gut. 2001 Feb;48(2):151-2 [11156631.001]
  • [Cites] Cancer. 1982 Dec 1;50(11):2496-503 [7139542.001]
  • [Cites] Gastroenterol Clin Biol. 2000 Dec;24(12):1205-10 [11173734.001]
  • [Cites] Endosc Surg Allied Technol. 1994 Feb;2(1):42-6 [8081915.001]
  • [Cites] Gastrointest Endosc. 2005 Jul;62(1):48-54 [15990819.001]
  • [Cites] Dtsch Med Wochenschr. 1997 Apr 4;122(14):432-8 [9138921.001]
  • (PMID = 19082886.001).
  • [ISSN] 1573-2568
  • [Journal-full-title] Digestive diseases and sciences
  • [ISO-abbreviation] Dig. Dis. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 451W47IQ8X / Sodium Chloride
  •  go-up   go-down


100. Vieth M, Stolte M: Elevated risk for gastric adenocarcinoma can be predicted from histomorphology. World J Gastroenterol; 2006 Oct 14;12(38):6109-14
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Elevated risk for gastric adenocarcinoma can be predicted from histomorphology.
  • The number of patients with gastric cancer has more than doubled since 1985 in developing countries.
  • Thus, the questions of whether it can be predicted from gastritis morphology, who is at risk and who has a lower risk of developing gastric carcinoma are raised.
  • The frequency of ulcerations among H pylori-infected individuals is estimated to be 13%, gastric cancer about 1% and MALT lymphoma around 0.1%.
  • Differences in topography, grade and activity of Helicobacter gastritis in the antrum and corpus might be good markers for identifying those who are at risk of developing gastric cancer.
  • It is known that the so-called corpus dominant H pylori gastritis is found more frequently among individuals with early and advanced gastric cancer and within high risk populations.
  • This is valid both for first-degree relatives of gastric cancer patients and for patients with gastric adenoma and hyperplastic polyps.
  • In conclusion, corpus-dominant H pylori gastritis is significantly more common in patients with advanced and early gastric cancer, first-degree relatives of patients with gastric cancer, patients with gastric adenoma and gastric hyperplastic polyps.
  • Therefore, all these patients are at risk of developing gastric cancer.
  • It appears that patients with a low acid output more frequently develop gastric cancer.
  • Large prospective long term studies are necessary to prove this and identify new reliable markers for gastric cancer development.
  • [MeSH-major] Adenocarcinoma / etiology. Gastritis / pathology. Stomach / pathology. Stomach Neoplasms / etiology

  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] World J Gastroenterol. 2001 Apr;7(2):243-7 [11819768.001]
  • [Cites] Tumour Biol. 1997;18(5):311-20 [9276031.001]
  • [Cites] Am J Gastroenterol. 1997 Dec;92(12):2220-4 [9399757.001]
  • [Cites] Virchows Arch. 1998 Apr;432(4):311-4 [9565339.001]
  • [Cites] Br J Cancer. 1998 Jul;78(2):263-6 [9683304.001]
  • [Cites] Aliment Pharmacol Ther. 1998 Aug;12(8):735-40 [9726386.001]
  • [Cites] J Gastroenterol Hepatol. 1998 Oct;13(10):1050-7 [9835323.001]
  • [Cites] Eur J Gastroenterol Hepatol. 1999 Jul;11(7):717-20 [10445789.001]
  • [Cites] Cancer. 1958 Nov-Dec;11(6):1149-55 [13608416.001]
  • [Cites] World J Gastroenterol. 2005 Feb 14;11(6):791-6 [15682469.001]
  • [Cites] World J Gastroenterol. 2005 Feb 21;11(7):976-81 [15742399.001]
  • [Cites] Best Pract Res Clin Gastroenterol. 2005 Dec;19(6):857-69 [16338646.001]
  • [Cites] Gut. 2000 May;46(5):639-44 [10764706.001]
  • [Cites] Gastroenterol Clin North Am. 2000 Dec;29(4):819-27 [11190066.001]
  • [Cites] Virchows Arch. 2000 Dec;437(6):581-90 [11193468.001]
  • [Cites] Digestion. 2001;64(1):30-9 [11549834.001]
  • [Cites] World J Gastroenterol. 2001 Apr;7(2):248-53 [11819769.001]
  • [Cites] Dig Dis Sci. 2002 Jun;47(6):1248-56 [12064799.001]
  • [Cites] J Clin Pathol. 2002 Oct;55(10):770-3 [12354805.001]
  • [Cites] Helicobacter. 2003 Feb;8(1):29-35 [12603614.001]
  • [Cites] Virchows Arch. 2003 Apr;442(4):317-21 [12715167.001]
  • [Cites] JAMA. 2004 Jan 14;291(2):187-94 [14722144.001]
  • [Cites] J Gastroenterol. 2004;39(4):324-8 [15168242.001]
  • [Cites] Eur J Cancer Prev. 2004 Oct;13(5):457-9 [15452460.001]
  • [Cites] Eur J Gastroenterol Hepatol. 2004 Nov;16(11):1183-8 [15489580.001]
  • [Cites] Endoscopy. 1983 Jan;15(1):8-11 [6822229.001]
  • [Cites] Cancer. 1986 Apr 15;57(8):1528-34 [2418943.001]
  • [Cites] Cancer Res. 1988 Jul 1;48(13):3554-60 [3288329.001]
  • [Cites] J Clin Pathol. 1989 Aug;42(8):834-9 [2768523.001]
  • [Cites] Z Gastroenterol. 1990 May;28(5):229-33 [2402931.001]
  • [Cites] Cancer. 1990 Nov 1;66(9):2047-51 [2224804.001]
  • [Cites] Cancer Causes Control. 1991 Jul;2(4):227-33 [1873452.001]
  • [Cites] Gut. 1992 Apr;33(4):429-31 [1582581.001]
  • [Cites] Cancer. 1992 Jul 1;70(1):50-5 [1606546.001]
  • [Cites] Virchows Arch A Pathol Anat Histopathol. 1992;420(6):489-98 [1609509.001]
  • [Cites] Cancer. 1992 Sep 15;70(6 Suppl):1727-31 [1516027.001]
  • [Cites] Cancer. 1993 Sep 15;72(6):1841-5 [8364862.001]
  • [Cites] Zentralbl Bakteriol. 1993 Sep;280(1-2):137-43 [8280935.001]
  • [Cites] Scand J Gastroenterol Suppl. 1994;201:28-34 [8047821.001]
  • [Cites] Virchows Arch. 1994;425(4):339-47 [7820298.001]
  • [Cites] Gut. 1995 Jan;36(1):12-6 [7890214.001]
  • [Cites] Z Gastroenterol. 1995 Feb;33(2):89-93 [7725762.001]
  • [Cites] Eur J Gastroenterol Hepatol. 1995 May;7(5):461-5 [7614109.001]
  • [Cites] Am J Surg Pathol. 1996 Oct;20(10):1161-81 [8827022.001]
  • [Cites] Virchows Arch. 1997 Jul;431(1):11-5 [9247628.001]
  • (PMID = 17036380.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] China
  • [Number-of-references] 47
  • [Other-IDs] NLM/ PMC4088102
  •  go-up   go-down






Advertisement