[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 100 of about 2624
1. Cuthbertson DJ, Ritchie D, Crooks D, Main G, Smith C, Vora J, Eljamel MS, Leese GP: Lymphocytic hypophysitis occurring simultaneously with a functioning pituitary adenoma. Endocr J; 2008 Aug;55(4):729-35
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lymphocytic hypophysitis occurring simultaneously with a functioning pituitary adenoma.
  • Lymphocytic Hypophysitis (LH) is a rare and previously under-recognised disorder, most commonly affecting young females in the post-partum period.
  • It presents clinically with symptoms and signs related to either a pituitary mass or hypopituitarism, frequently mimicking a pituitary adenoma; the diagnosis of LH can only be made histologically with the presence of a dense lymphocytic infiltration usually confined to the anterior pituitary.
  • We present two case histories of patients who presented with symptoms suggestive of a functioning pituitary adenoma who also had concomitant LH confirmed histologically.
  • In both patients, magnetic resonance (MR) imaging of the pituitary demonstrated an enlarged partially cystic pituitary mass with slight suprasellar extension.
  • Both patients were treated surgically with transphenoidal drainage and excision and histological examination of the surgical specimens demonstrated a mixture of pathologies with fragments of adenohypophyseal tissue (staining positive for ACTH and prolactin respectively) with a dense chronic inflammatory cell infiltrate suggestive of LH in nearby normal anterior pituitary.
  • In both cases a joint diagnosis of a functioning pituitary adenoma with LH was made.
  • [MeSH-major] Adenoma / complications. Pituitary Diseases / complications. Pituitary Neoplasms / complications

  • Genetic Alliance. consumer health - Lymphocytic hypophysitis.
  • MedlinePlus Health Information. consumer health - Pituitary Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18497455.001).
  • [ISSN] 1348-4540
  • [Journal-full-title] Endocrine journal
  • [ISO-abbreviation] Endocr. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


2. Georgitsi M, Raitila A, Karhu A, Tuppurainen K, Mäkinen MJ, Vierimaa O, Paschke R, Saeger W, van der Luijt RB, Sane T, Robledo M, De Menis E, Weil RJ, Wasik A, Zielinski G, Lucewicz O, Lubinski J, Launonen V, Vahteristo P, Aaltonen LA: Molecular diagnosis of pituitary adenoma predisposition caused by aryl hydrocarbon receptor-interacting protein gene mutations. Proc Natl Acad Sci U S A; 2007 Mar 6;104(10):4101-5
SciCrunch. Clinical Genomic Database: Data: Gene Annotation .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Molecular diagnosis of pituitary adenoma predisposition caused by aryl hydrocarbon receptor-interacting protein gene mutations.
  • Pituitary adenomas are common neoplasms of the anterior pituitary gland.
  • Germ-line mutations in the aryl hydrocarbon receptor-interacting protein (AIP) gene cause pituitary adenoma predisposition (PAP), a recent discovery based on genetic studies in Northern Finland.
  • Typically, PAP patients were of a young age at diagnosis but did not display a strong family history of pituitary adenomas.
  • To evaluate the role of AIP in pituitary adenoma susceptibility in other populations and to gain insight into patient selection for molecular screening of the condition, we investigated the possible contribution of AIP mutations in pituitary tumorigenesis in patients from Europe and the United States.
  • A total of 460 patients were investigated by AIP sequencing: young acromegaly patients, unselected acromegaly patients, unselected pituitary adenoma patients, and endocrine neoplasia-predisposition patients who were negative for MEN1 mutations.
  • Because many of the patients displayed no family history of pituitary adenomas, detection of the condition appears challenging.
  • Feasibility of AIP immunohistochemistry (IHC) as a prescreening tool was tested in 50 adenomas: 12 AIP mutation-positive versus 38 mutation-negative pituitary tumors.
  • [MeSH-major] Acromegaly / genetics. Founder Effect. Genetic Predisposition to Disease. Mutation. Pituitary Neoplasms / genetics. Proteins / genetics

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • SciCrunch. OMIM: Data: Gene Annotation .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Nat Rev Cancer. 2005 May;5(5):367-75 [15864278.001]
  • [Cites] J Clin Endocrinol Metab. 1998 Oct;83(10):3419-26 [9768641.001]
  • [Cites] N Engl J Med. 2005 May 5;352(18):1851-60 [15872200.001]
  • [Cites] Horm Metab Res. 2005 Jun;37(6):347-54 [16001326.001]
  • [Cites] J Clin Endocrinol Metab. 2005 Jul;90(7):4081-6 [15886256.001]
  • [Cites] Eur J Endocrinol. 2005 Aug;153(2):187-93 [16061822.001]
  • [Cites] Gene. 2006 Feb 1;366(2):219-27 [16226402.001]
  • [Cites] Science. 2006 May 26;312(5777):1228-30 [16728643.001]
  • [Cites] J Biol Chem. 2006 Aug 25;281(34):24721-7 [16807248.001]
  • [Cites] J Clin Endocrinol Metab. 2006 Sep;91(9):3316-23 [16787992.001]
  • [Cites] J Clin Endocrinol Metab. 2000 Jan;85(1):168-74 [10634382.001]
  • [Cites] J Clin Endocrinol Metab. 2000 Feb;85(2):526-9 [10690849.001]
  • [Cites] Clin Endocrinol (Oxf). 2000 Apr;52(4):509-18 [10762295.001]
  • [Cites] J Biol Chem. 2000 Nov 17;275(46):36407-14 [10961990.001]
  • [Cites] Endocr Relat Cancer. 2001 Dec;8(4):287-305 [11733226.001]
  • [Cites] J Clin Endocrinol Metab. 2001 Dec;86(12):5658-71 [11739416.001]
  • [Cites] Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15558-63 [17030811.001]
  • [Cites] J Clin Endocrinol Metab. 2006 Dec;91(12):5126-9 [17018653.001]
  • [Cites] Chem Biol Interact. 2002 Sep 20;141(1-2):25-40 [12213383.001]
  • [Cites] J Biol Chem. 2003 Feb 14;278(7):4467-73 [12482853.001]
  • [Cites] J Med Genet. 2003 May;40(5):e72 [12746426.001]
  • [Cites] J Biol Chem. 2003 Aug 29;278(35):33351-63 [12810716.001]
  • [Cites] J Clin Invest. 2003 Dec;112(11):1603-18 [14660734.001]
  • [Cites] J Clin Endocrinol Metab. 2004 Feb;89(2):667-74 [14764779.001]
  • [Cites] Endocr Rev. 2004 Feb;25(1):102-52 [14769829.001]
  • [Cites] Nat Rev Cancer. 2004 Apr;4(4):285-95 [15057288.001]
  • [Cites] Growth Horm IGF Res. 2004 Jun;14 Suppl A:S90-6 [15135786.001]
  • [Cites] Eur J Endocrinol. 2004 Oct;151(4):431-2 [15476440.001]
  • [Cites] J Mol Biol. 1991 Jul 5;220(1):49-65 [2067018.001]
  • [Cites] Nucleic Acids Res. 1996 Sep 1;24(17):3439-52 [8811101.001]
  • [Cites] J Biol Chem. 1997 Apr 25;272(17):11452-6 [9111057.001]
  • [Cites] J Clin Endocrinol Metab. 2005 May;90(5):2731-9 [15741257.001]
  • (PMID = 17360484.001).
  • [ISSN] 0027-8424
  • [Journal-full-title] Proceedings of the National Academy of Sciences of the United States of America
  • [ISO-abbreviation] Proc. Natl. Acad. Sci. U.S.A.
  • [Language] eng
  • [Databank-accession-numbers] GENBANK/ EF203234/ EF203235/ EF203236/ EF203237/ EF203238/ EF203239/ EF203240
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Intracellular Signaling Peptides and Proteins; 0 / Proteins; 0 / aryl hydrocarbon receptor-interacting protein
  • [Other-IDs] NLM/ PMC1820715
  •  go-up   go-down


3. Rao S, Rajkumar A, Kuruvilla S: Sellar lesion: not always a pituitary adenoma. Indian J Pathol Microbiol; 2008 Apr-Jun;51(2):269-70
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sellar lesion: not always a pituitary adenoma.
  • Inflammatory lesions of the hypophysis account for 0.5% of all symptomatic diseases of the pituitary, which include lymphocytic hypophysitis, granulomatous hypophysitis with or without specific etiology and pituitary abscess.
  • Based on preliminary investigations, a clinical diagnosis of pituitary adenoma was made and the pituitary gland was surgically excised.
  • Histopathological examination showed caseating granulomas, along with normal areas of preserved pituitary gland and a final diagnosis of tuberculous hypophysitis was made.
  • This case is being documented due to the extremely rare involvement of the pituitary gland by granulomatous lesions such as tuberculosis and to emphasize the role of intraoperative consultation to obviate the need for radical surgery in such lesions.
  • [MeSH-major] Adenoma / diagnosis. Pituitary Diseases / diagnosis. Pituitary Neoplasms / diagnosis. Tuberculosis, Endocrine / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged. Sella Turcica / pathology. Tuberculoma / diagnosis. Tuberculoma / pathology

  • MedlinePlus Health Information. consumer health - Pituitary Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18603706.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article
  • [Publication-country] India
  •  go-up   go-down


Advertisement
4. Er U, Gürses L, Saka C, Belen D, Yiğitkanli K, Simşek S, Akin I, Bavbek M: Sublabial transseptal approach to pituitary adenomas with special emphasis on rhinological complications. Turk Neurosurg; 2008 Oct;18(4):425-30
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sublabial transseptal approach to pituitary adenomas with special emphasis on rhinological complications.
  • OBJECTIVE: The aim of this presentation is to show that the sublabial transseptal transsphenoidal approach to pituitary adenomas is the least invasive anatomic route with the lowest postoperative complication rates.
  • PATIENTS AND METHOD: This study was based on a retrospective analysis of 276 patients with a diagnosis of pituitary adenoma who were surgically treated via the sublabial transsphenoidal route.
  • [MeSH-major] Adenoma / surgery. Neurosurgical Procedures / methods. Nose Diseases / epidemiology. Nose Diseases / etiology. Pituitary Neoplasms / surgery. Postoperative Complications / epidemiology
  • [MeSH-minor] ACTH-Secreting Pituitary Adenoma / surgery. Adult. Aged. Diabetes Insipidus / epidemiology. Diabetes Insipidus / etiology. Female. Growth Hormone-Secreting Pituitary Adenoma / surgery. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Nasal Mucosa / injuries. Nasal Mucosa / pathology. Nasal Septum / injuries. Nasal Septum / pathology. Neoplasm Recurrence, Local / epidemiology. Prolactinoma / surgery. Retrospective Studies. Thyrotropin / metabolism. Tomography, X-Ray Computed. Treatment Outcome. Water-Electrolyte Imbalance / epidemiology. Water-Electrolyte Imbalance / etiology. Young Adult

  • MedlinePlus Health Information. consumer health - After Surgery.
  • MedlinePlus Health Information. consumer health - Nose Injuries and Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19107694.001).
  • [ISSN] 1019-5149
  • [Journal-full-title] Turkish neurosurgery
  • [ISO-abbreviation] Turk Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Turkey
  • [Chemical-registry-number] 9002-71-5 / Thyrotropin
  •  go-up   go-down


5. Picozzi P, Losa M, Mortini P, Valle MA, Franzin A, Attuati L, da Passano CF, Giovanelli M: Radiosurgery and the prevention of regrowth of incompletely removed nonfunctioning pituitary adenomas. J Neurosurg; 2005 Jan;102(s_supplement):71-74

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radiosurgery and the prevention of regrowth of incompletely removed nonfunctioning pituitary adenomas.
  • OBJECT: The authors studied the efficacy of gamma knife radiosurgery (GKS) in the prevention of regrowth of nonfunctioning pituitary adenomas (NPA).
  • All patients had undergone surgery in our department and recurrent or residual adenoma was demonstrated on postoperative MR imaging.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 28306434.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; gamma knife surgery / nonfunctioning pituitary adenoma / pituitary
  •  go-up   go-down


6. Nakahara K, Oka H, Utsuki S, Iida H, Kurita M, Mochizuki T, Fujii K: Pituitary apoplexy manifesting as diffuse subarachnoid hemorrhage. Neurol Med Chir (Tokyo); 2006 Dec;46(12):594-7
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pituitary apoplexy manifesting as diffuse subarachnoid hemorrhage.
  • A 46-year-old woman presented with hemorrhage from a non-functioning pituitary adenoma manifesting as sudden onset of severe headache.
  • The patient underwent transnasal transsphenoidal removal of the pituitary adenoma.
  • This type of SAH with intratumoral hematoma simulates rupture of an anterior cerebral artery aneurysm.
  • [MeSH-major] Adenoma / complications. Pituitary Apoplexy / complications. Pituitary Neoplasms / complications. Subarachnoid Hemorrhage / etiology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17185885.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


7. Walsh MT, Couldwell WT: Symptomatic cystic degeneration of a clinically silent corticotroph tumor of the pituitary gland. Skull Base; 2010 Sep;20(5):367-70
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Symptomatic cystic degeneration of a clinically silent corticotroph tumor of the pituitary gland.
  • Clinically silent corticotroph tumors of the pituitary gland are those tumors that stain for adrenocorticotropic hormone (ACTH) but do not manifest with clinical or laboratory features of Cushing disease.
  • These tumors have been described as exhibiting more aggressive behavior than other nonfunctional pituitary tumors.
  • We present an unusual case of a clinically silent corticotropic adenoma of the pituitary gland that underwent cystic degeneration following recurrence after transsphenoidal surgery and radiation therapy.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Nucleic Acids Res. 1983 Oct 25;11(20):7191-203 [6634412.001]
  • (PMID = 21359002.001).
  • [ISSN] 1532-0065
  • [Journal-full-title] Skull base : official journal of North American Skull Base Society ... [et al.]
  • [ISO-abbreviation] Skull Base
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3023327
  • [Keywords] NOTNLM ; Cortisol / Cushing disease / adrenocorticotropic hormone / corticotroph cells / cystic degeneration / nonfunctional pituitary adenoma
  •  go-up   go-down


8. González-Tortosa J, Poza-Poza M, Ruiz-Espejo-Vilar A: [Pituitary adenoma apoplexy after spinal anaesthesia. Report of two cases and review of the literature]. Neurocirugia (Astur); 2009 Oct;20(5):484-93
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pituitary adenoma apoplexy after spinal anaesthesia. Report of two cases and review of the literature].
  • [Transliterated title] Apoplejía de adenoma hipofi sario no funcionante tras anestesia espinal. A propósito de dos casos.
  • Two cases of pituitary apoplexy occurring after spinal anaesthesia are described.
  • We propose the arterial hypotension as a possible pathogenetic mechanism of pituitary adenoma apoplexy.
  • [MeSH-major] Adenoma / diagnosis. Anesthesia, Spinal / adverse effects. Pituitary Apoplexy / etiology. Pituitary Neoplasms / diagnosis. Postoperative Complications / etiology
  • [MeSH-minor] Blood Pressure. Diabetes Insipidus, Neurogenic / etiology. Diagnosis, Differential. Erectile Dysfunction / etiology. Humans. Hyponatremia / etiology. Hypopituitarism / etiology. Incidental Findings. Intracranial Hemorrhages / etiology. Intracranial Pressure. Male. Menisci, Tibial / surgery. Middle Aged. Oculomotor Nerve Diseases / etiology. Vision Disorders / etiology

  • MedlinePlus Health Information. consumer health - After Surgery.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19830374.001).
  • [ISSN] 1130-1473
  • [Journal-full-title] Neurocirugía (Asturias, Spain)
  • [ISO-abbreviation] Neurocirugia (Astur)
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 72
  •  go-up   go-down


9. Tlachacova D, Schmitt M, Novotny J Jr, Novotny J, Majali M, Liscak R: A comparison of the gamma knife model C and the Automatic Positioning System with Leksell model B. J Neurosurg; 2005 Jan;102(s_supplement):25-28
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Data were analyzed in patients in whom the following diagnoses had been made: vestibular schwannoma, pituitary adenoma, meningioma, solitary metastasis, and other benign and malignant solitary tumors.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 28306471.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; conformity index / extracranial exposure / staff exposure / stereotactic radiosurgery
  •  go-up   go-down


10. Killory BD, Kresl JJ, Wait SD, Ponce FA, Porter R, White WL: Hypofractionated Cyberknife Radiosurgery for Perichiasmatic Pituitary Adenomas: Early Results. Neurosurgery; 2009 Feb 01;64(suppl_2):A19-A25

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hypofractionated Cyberknife Radiosurgery for Perichiasmatic Pituitary Adenomas: Early Results.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 28175597.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


11. Pollock BE: Radiotherapy and Radiosurgery for Hormone Secreting Pituitary Adenomas. Neurosurgery; 2010 May 01;66(5):E1030

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radiotherapy and Radiosurgery for Hormone Secreting Pituitary Adenomas.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 28173407.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


12. Scheithauer BW, Gaffey TA, Lloyd RV, Sebo TJ, Kovacs KT, Horvath E, Yapıcıer Ö, Young WF, Meyer FB, Kuroki T, Riehle DL, Laws ER: Pathobiology of Pituitary Adenomas and Carcinomas. Neurosurgery; 2006 Aug 01;59(2):341-353

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pathobiology of Pituitary Adenomas and Carcinomas.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 28180650.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


13. Kobayashi T, Mori Y, Uchiyama Y, Kida Y, Fujitani S: Long-term results of gamma knife surgery for growth hormone-producing pituitary adenoma: is the disease difficult to cure? J Neurosurg; 2005 Jan;102(s_supplement):119-123

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term results of gamma knife surgery for growth hormone-producing pituitary adenoma: is the disease difficult to cure?
  • OBJECT: The authors conducted a study to determine the long-term results of gamma knife surgery for residual or recurrent growth hormine (GH)-producing pituitary adenomas and to compare the results with those after treatment of other pituitary adenomas.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 28306435.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; gamma knife surgery / growth hormone—producing pituitary adenoma / insulin-like growth factor
  •  go-up   go-down


14. Chibbaro S, Benvenuti L, Carnesecchi S, Faggionato F, Gagliardi R: An interesting case of a pituitary adenoma apoplexy mimicking an acute meningitis. Case report. J Neurosurg Sci; 2007 Jun;51(2):65-9; discussion 68-9
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An interesting case of a pituitary adenoma apoplexy mimicking an acute meningitis. Case report.
  • Apoplexy of a pituitary adenoma is a rare and under-diagnosed clinical occurrence.
  • It results from either infarction or haemorrhage into an adenoma of the pituitary gland.
  • A 33-year-old male suffered a pituitary macroadenoma apoplexy, clinically indistinguishable from an infectious meningitis at presentation.
  • In conclusion the authors believe that, despite many reports in the literature, encouraging conservative management in pituitary apoplexy by administering intravenous steroids, surgery should be undertaken in order to avoid eventual visual field defects, relieve pituitary gland compression and prevent a possible recurrent apoplectic episode or tumor re-growth.
  • [MeSH-major] Adenoma / complications. Meningitis / diagnosis. Pituitary Apoplexy / diagnosis. Pituitary Gland / pathology. Pituitary Neoplasms / complications
  • [MeSH-minor] Acute Disease. Adult. Brain Infarction / complications. Brain Infarction / etiology. Brain Infarction / pathology. Diagnosis, Differential. Headache / etiology. Humans. Hydrocortisone / therapeutic use. Hypopituitarism / drug therapy. Hypopituitarism / etiology. Hypopituitarism / pathology. Magnetic Resonance Imaging. Male. Neck Pain / etiology. Neurosurgical Procedures / methods. Oculomotor Nerve Diseases / etiology. Postoperative Complications / etiology. Tomography, X-Ray Computed. Treatment Outcome. Unconsciousness / etiology. Vomiting / etiology

  • MedlinePlus Health Information. consumer health - Meningitis.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. HYDROCORTISONE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17571037.001).
  • [ISSN] 0390-5616
  • [Journal-full-title] Journal of neurosurgical sciences
  • [ISO-abbreviation] J Neurosurg Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] WI4X0X7BPJ / Hydrocortisone
  •  go-up   go-down


15. Ma CY, Shi JX: [Male infertility caused by pituitary adenoma]. Zhonghua Nan Ke Xue; 2006 Jan;12(1):75-7, 79
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Male infertility caused by pituitary adenoma].
  • Pituitary adenoma is one of the important etiologies of male infertility.
  • The early diagnosis of pituitary adenoma that caused infertility is not difficult with the help of modem incretion examination and imaging technique.
  • The treatment focused on pituitary adenoma is no doubt the optimal choice of this kind of male infertility.
  • [MeSH-major] Growth Hormone-Secreting Pituitary Adenoma / complications. Infertility, Male / etiology. Pituitary Neoplasms / complications

  • Genetic Alliance. consumer health - infertility.
  • MedlinePlus Health Information. consumer health - Male Infertility.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16483168.001).
  • [ISSN] 1009-3591
  • [Journal-full-title] Zhonghua nan ke xue = National journal of andrology
  • [ISO-abbreviation] Zhonghua Nan Ke Xue
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] China
  • [Number-of-references] 20
  •  go-up   go-down


16. Harzallah L, Boudabbous S, Migaw H, Harzallah F, Ach K, Hamdi I, Bakir D, Chaieb L, Kraiem C: [MRI and pituitary adenoma]. Ann Endocrinol (Paris); 2006 Sep;67(4):325-30
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [MRI and pituitary adenoma].
  • Pituitary is the most important gland of the organism which can be affected by many diseases, especially by adenomatous processes.
  • Classically macroadenoma, microadenoma and picoadenoma are described, according to the size of the pituitary adenoma.
  • The diagnosis of microadenoma was long considered a highly difficult task and that of picoadenoma was impossible by computed tomography.
  • Recently, the high resolution of multiplanar MRI has enabled the diagnosis of microadenomas measuring less than 3 mm (picoadenoma).
  • For macroadenoma, MRI not only contributes to diagnosis but is particularly important to assess the extension and to detect possible complications.
  • The aim of our study is to illustrate MRI features in pituitary adenoma.
  • [MeSH-major] Adenoma / diagnosis. Pituitary Neoplasms / diagnosis
  • [MeSH-minor] Humans. Magnetic Resonance Imaging / methods. Pituitary Gland / anatomy & histology. Sensitivity and Specificity

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17072237.001).
  • [ISSN] 0003-4266
  • [Journal-full-title] Annales d'endocrinologie
  • [ISO-abbreviation] Ann. Endocrinol. (Paris)
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
  •  go-up   go-down


17. Alexander AA, Niktash N, Kardon DE, Sadeghi N: Ectopic nasopharyngeal pituitary adenoma resected with endoscopic technique. Ear Nose Throat J; 2008 Jul;87(7):E8-10
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ectopic nasopharyngeal pituitary adenoma resected with endoscopic technique.
  • Although initially the mass was suspected to be a minor salivary gland tumor, histopathologic analysis led to a diagnosis of pituitary adenoma.
  • The ectopic tumor was removed via transnasal en bloc resection with partial adjacent septal resection.
  • Final pathology confirmed the diagnosis.
  • [MeSH-major] Adenoma / surgery. Endoscopy. Nasopharyngeal Neoplasms / surgery. Pituitary Neoplasms / surgery

  • MedlinePlus Health Information. consumer health - Endoscopy.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18633921.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


18. Cohn-Zurita F, Guinto-Balanzar G, Pérez-Cerdán H: [Neurocysticercosis associated with pituitary adenoma. Case report and literature review]. Cir Cir; 2006 Jan-Feb;74(1):47-9
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Neurocysticercosis associated with pituitary adenoma. Case report and literature review].
  • [Transliterated title] Cisticercosis cerebral asociada con adenoma pituitario. Reporte de un caso y revisión de la literatura.
  • However, the clinical association between pituitary adenoma and suprasellar cysts is unknown.
  • Imaging studies including CT and MRI revealed a moderate size pituitary adenoma along with multiple cysts located in the subarachnoid cisterns in the Sylvian fissure and around the suprasellar cistern.
  • The patient subsequently underwent surgical exploration by means of a right frontotemporal craniotomy with pituitary adenoma resection and cyst removal.
  • The histopathological exam was consistent with non-functioning pituitary adenoma and racemosus cysticercosis.
  • CONCLUSIONS: There are no reports of a clinical association between pituitary adenoma and racemosus cysticercosis.
  • [MeSH-major] Adenoma / complications. Neurocysticercosis / complications. Pituitary Neoplasms / complications

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17257488.001).
  • [ISSN] 0009-7411
  • [Journal-full-title] Cirugía y cirujanos
  • [ISO-abbreviation] Cir Cir
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Mexico
  • [Number-of-references] 5
  •  go-up   go-down


19. De Witte O, Makiese O, Wikler D, Levivier M, Vandensteene A, Pandin P, Balériaux D, Brotchi J: [Transsphenoidal approach with low field MRI for pituitary adenoma]. Neurochirurgie; 2005 Dec;51(6):577-83
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Transsphenoidal approach with low field MRI for pituitary adenoma].
  • [Transliterated title] Apport de la résonance magnétique per-opératoire à bas champs dans la chirurgie de l'adénome hypophysaire.
  • INTRODUCTION: Appropriate evaluation of resection remains one of the major difficulties of surgical treatment of pituitary adenoma.
  • Endoscopy provides useful information but may no distinguish well residual adenoma from the pituitary gland.
  • We report our experience with low field intraoperative MRI in surgical treatment of pituitary adenoma.
  • POPULATION: Intraoperative MRI (Polestar N10, 30 patients and Polestar N20, 17 patients) was performed in 45 consecutive patients undergoing surgery for pituitary adenoma.
  • RESULTS: Intraoperative images were unavailable for two patients due to small size of the neck and the pituitary glands which were not in the middle in the field of view.
  • For the others, the pituitary glands were in the field of view and the intraoperative scans could be used for comparison.
  • A control showed no residual adenoma but hemostatic tissue.
  • CONCLUSION: Low field intraoperative MRI is an excellent technique for controlling the size of pituitary adenoma resection.
  • [MeSH-major] Adenoma / diagnosis. Magnetic Resonance Imaging. Neurosurgical Procedures / methods. Pituitary Neoplasms / diagnosis

  • MedlinePlus Health Information. consumer health - MRI Scans.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16553330.001).
  • [ISSN] 0028-3770
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] Clinical Trial; English Abstract; Journal Article
  • [Publication-country] France
  •  go-up   go-down


20. Mittelbronn M, Meyermann R, Honegger J: Atypical pituitary adenoma exhibiting densely secretory granules and basophilia without hormone production. Neuro Endocrinol Lett; 2006 Feb-Apr;27(1-2):93-6
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Atypical pituitary adenoma exhibiting densely secretory granules and basophilia without hormone production.
  • Radiological examination revealed a pituitary tumor.
  • Endocrinological investigations showed no pathological alterations of anterior pituitary function.
  • Neuropathological examinations revealed a pituitary gland adenoma with an elevated proliferation rate (MIB-1 index 4-5 %) as well as an elevated p53 expression leading to the diagnosis of an atypical pituitary adenoma.
  • This discrepancy might be due to a production of unfunctional pre-stages of pituitary gland proteins in this fast growing neoplasm.
  • [MeSH-major] Adenoma / metabolism. Adenoma / pathology. Pituitary Hormones / metabolism. Pituitary Neoplasms / metabolism. Pituitary Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • Hazardous Substances Data Bank. HYDROCORTISONE .
  • Hazardous Substances Data Bank. Corticotropin .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16648809.001).
  • [ISSN] 0172-780X
  • [Journal-full-title] Neuro endocrinology letters
  • [ISO-abbreviation] Neuro Endocrinol. Lett.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Sweden
  • [Chemical-registry-number] 0 / Pituitary Hormones; 0 / Tumor Suppressor Protein p53; 12629-01-5 / Human Growth Hormone; 67763-96-6 / Insulin-Like Growth Factor I; 9002-60-2 / Adrenocorticotropic Hormone; 9002-62-4 / Prolactin; WI4X0X7BPJ / Hydrocortisone
  •  go-up   go-down


21. Wang SJ, Hung CW, Fuh JL, Lirng JF, Hwu CM: Cranial autonomic symptoms in patients with pituitary adenoma presenting with headaches. Acta Neurol Taiwan; 2009 Jun;18(2):104-12
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cranial autonomic symptoms in patients with pituitary adenoma presenting with headaches.
  • Different types of symptomatic trigeminal autonomic cephalalgias (TACs) have been reported in patients with pituitary adenoma.
  • We investigated the significance of the presence of cranial autonomic symptoms (CAS) in patients with pituitary adenoma presenting with headaches.
  • The records of patients with pituitary adenoma from 1998 to 2004 in our headache clinic were reviewed including headache profile, presence or absence of CAS, and the characteristics of the pituitary adenoma.
  • CAS were ascertained if one or more autonomic symptoms defined for the diagnosis of TACs in the International Classification of Headache Disorders, 2nd edition (ICHD-2) was identified.
  • Thirty-three patients (24F/9M) with pituitary adenoma presenting with headache were recruited for this study: 18 with CAS (55%) and 15 without.
  • The presence and absence of CAS in pituitary adenoma-associated headache were associated with different characteristics of the underlying pituitary adenomas including side concordance and incidence of acromegaly and macroadenoma.
  • [MeSH-major] Adenoma / complications. Autonomic Nervous System Diseases / complications. Cranial Nerve Diseases / complications. Headache / etiology. Pituitary Neoplasms / complications

  • MedlinePlus Health Information. consumer health - Autonomic Nervous System Disorders.
  • MedlinePlus Health Information. consumer health - Headache.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19673362.001).
  • [ISSN] 1028-768X
  • [Journal-full-title] Acta neurologica Taiwanica
  • [ISO-abbreviation] Acta Neurol Taiwan
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China (Republic : 1949- )
  •  go-up   go-down


22. Gallelli MF, Cabrera Blatter MF, Castillo V: A comparative study by age and gender of the pituitary adenoma and ACTH and alpha-MSH secretion in dogs with pituitary-dependent hyperadrenocorticism. Res Vet Sci; 2010 Feb;88(1):33-40
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A comparative study by age and gender of the pituitary adenoma and ACTH and alpha-MSH secretion in dogs with pituitary-dependent hyperadrenocorticism.
  • Pituitary-dependent hyperadrenocorticism (PDH) is frequent in dogs.
  • Using magnetic resonance, pituitary tumours were intra-sellar (IS) in 30.8% and extra-sellar (ES) in 62.6% and the pars intermedia (PI) was affected in 6.5%.
  • Differences in adenoma size according to gender and their age-related frequency of apparition could be because of different origins of the corticotrophinoma.
  • [MeSH-major] ACTH-Secreting Pituitary Adenoma / veterinary. Adrenocortical Hyperfunction / veterinary. Adrenocorticotropic Hormone / secretion. Dog Diseases / pathology. Pituitary Neoplasms / veterinary. alpha-MSH / secretion
  • [MeSH-minor] Age Factors. Animals. Dogs. Female. Magnetic Resonance Imaging. Male. Pituitary Gland / pathology. Pituitary Gland / physiopathology. Pituitary Gland / secretion. Retrospective Studies. Sex Factors

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • Hazardous Substances Data Bank. Corticotropin .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2009 Elsevier Ltd. All rights reserved.
  • (PMID = 19683322.001).
  • [ISSN] 1532-2661
  • [Journal-full-title] Research in veterinary science
  • [ISO-abbreviation] Res. Vet. Sci.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 581-05-5 / alpha-MSH; 9002-60-2 / Adrenocorticotropic Hormone
  •  go-up   go-down


23. Alons K, Bergé SJ, Rieu PN, Meijer GJ: [Treatment of macroglossia due to acromegaly]. Ned Tijdschr Tandheelkd; 2010 Jun;117(6):321-4
Genetic Alliance. consumer health - Macroglossia.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • At the age of 55 years she was diagnosed with acromegaly induced by a adenoma of the pituitary gland, which had been removed surgically.

  • Genetic Alliance. consumer health - Acromegaly.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20614796.001).
  • [ISSN] 0028-2200
  • [Journal-full-title] Nederlands tijdschrift voor tandheelkunde
  • [ISO-abbreviation] Ned Tijdschr Tandheelkd
  • [Language] dut
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Netherlands
  •  go-up   go-down


24. Yoshino A, Katayama Y, Watanabe T, Ogino A, Ohta T, Komine C, Yokoyama T, Fukushima T, Hirota H: Apoplexy accompanying pituitary adenoma as a complication of preoperative anterior pituitary function tests. Acta Neurochir (Wien); 2007 Jun;149(6):557-65; discussion 565
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Apoplexy accompanying pituitary adenoma as a complication of preoperative anterior pituitary function tests.
  • Pituitary apoplexy occurs as a very rare complication of the pituitary function test.
  • We have experienced two cases of pituitary apoplexy following anterior pituitary function tests for preoperative assessment: a triple bolus test and a TRH test.
  • The combined data suggest that pituitary function tests have the potential to precipitate pituitary apoplexy, and its manifestations range from a clinically benign event to a catastrophic presentation with permanent neurological deficits or even death, although most patients may fortunately have a good outcome.
  • We suggest that the pituitary function test should not be done as a routine test, and when such a test is planned, the patient should be observed with caution for any symptomatic changes for at least 2 hours following the test for appropriate treatment.
  • Further, MRI, especially enhanced studies, may provide an earlier diagnosis of the pituitary apoplexy since CT scan images often fail to demonstrate either density changes or obvious enlargement of the pituitary adenoma at the acute stage.
  • [MeSH-major] Adenoma, Acidophil / surgery. Gonadotropin-Releasing Hormone / adverse effects. Pituitary Apoplexy / chemically induced. Pituitary Function Tests / adverse effects. Pituitary Neoplasms / surgery. Thyrotropin-Releasing Hormone / adverse effects
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Diagnosis, Differential. Female. Humans. Hypophysectomy. Magnetic Resonance Imaging. Male. Middle Aged. Pituitary Gland / pathology. Preoperative Care. Reoperation. Tomography, X-Ray Computed

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17468811.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Austria
  • [Chemical-registry-number] 33515-09-2 / Gonadotropin-Releasing Hormone; 5Y5F15120W / Thyrotropin-Releasing Hormone
  • [Number-of-references] 32
  •  go-up   go-down


25. Huang WY, Chien YY, Wu CL, Weng WC, Peng TI, Chen HC: Pituitary adenoma apoplexy with initial presentation mimicking bacterial meningoencephalitis: a case report. Am J Emerg Med; 2009 May;27(4):517.e1-4
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pituitary adenoma apoplexy with initial presentation mimicking bacterial meningoencephalitis: a case report.
  • Pituitary apoplexy is a rare but life-threatening disorder.
  • To the best of our knowledge, pituitary apoplexy with an initial presentation mimicking infectious meningoencephalitis had rarely been reported in the literature.
  • Further examinations indicated a diagnosis of pituitary adenoma with apoplexy.
  • [MeSH-major] Adenoma / diagnosis. Meningoencephalitis / diagnosis. Pituitary Apoplexy / diagnosis. Pituitary Neoplasms / diagnosis
  • [MeSH-minor] Biomarkers / blood. Biomarkers / cerebrospinal fluid. Diagnosis, Differential. Diagnostic Errors / prevention & control. Humans. Male. Middle Aged

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19555639.001).
  • [ISSN] 1532-8171
  • [Journal-full-title] The American journal of emergency medicine
  • [ISO-abbreviation] Am J Emerg Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers
  • [Number-of-references] 14
  •  go-up   go-down


26. Gul S, Bahadir B, Dusak A, Kalayci M, Edebali N, Acikgoz B: Spherical amyloid deposition in a prolactin-producing pituitary adenoma. Neuropathology; 2009 Feb;29(1):81-4
Hazardous Substances Data Bank. C.I. DIRECT RED 28 .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spherical amyloid deposition in a prolactin-producing pituitary adenoma.
  • MRI demonstrated a mass arising from the pituitary gland.
  • The patient underwent trans-sphenoidal resection of the pituitary adenoma.
  • Histological examination revealed an adenoma with spheroid amyloid deposits adjacent to prolactin-staining adenoma cells.
  • [MeSH-major] Adenoma / pathology. Amyloid / metabolism. Pituitary Neoplasms / pathology
  • [MeSH-minor] Adult. Birefringence. Congo Red. Humans. Immunohistochemistry. Keratins / metabolism. Magnetic Resonance Imaging. Male. Pituitary Hormones, Anterior / metabolism. Prolactin / metabolism

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [ErratumIn] Neuropathology. 2009 Apr;29(2):208
  • (PMID = 18498287.001).
  • [ISSN] 1440-1789
  • [Journal-full-title] Neuropathology : official journal of the Japanese Society of Neuropathology
  • [ISO-abbreviation] Neuropathology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Amyloid; 0 / Pituitary Hormones, Anterior; 3U05FHG59S / Congo Red; 68238-35-7 / Keratins; 9002-62-4 / Prolactin
  •  go-up   go-down


27. López Hernández N, García Escrivá A, Moltó Jordá JM, García Barragán N: [Massive cerebral infarction secondary to apoplexy due to pituitary adenoma]. Neurologia; 2008 May;23(4):248-55
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Massive cerebral infarction secondary to apoplexy due to pituitary adenoma].
  • [Transliterated title] Infarto cerebral masivo secundario a apoplejía de un adenoma hipofisario.
  • INTRODUCTION: Pituitary apoplexy is a rare clinical entity.
  • It may initially begin as a meningeal syndrome, in which neuroimaging techniques may be fundamental, above all resonance magnetic imaging for a correct diagnosis of the disease and its complications.
  • CASE REPORT: We report the case of a 23 year-old male who suffered a massive stroke due to bilateral carotid compression in its intracavernous portion due to apoplexy of a previously unknown pituitary tumor.
  • An exhaustive review of cases and series of patients with pituitary apoplexy related stroke is also presented.
  • [MeSH-major] Adenoma / complications. Cerebral Infarction / etiology. Pituitary Apoplexy / complications. Pituitary Neoplasms / complications

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18516746.001).
  • [ISSN] 0213-4853
  • [Journal-full-title] Neurología (Barcelona, Spain)
  • [ISO-abbreviation] Neurologia
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 32
  •  go-up   go-down


28. De Menis E, Roncaroli F, Calvari V, Chiarini V, Pauletto P, Camerino G, Cremonini N: Corticotroph adenoma of the pituitary in a patient with X-linked adrenal hypoplasia congenita due to a novel mutation of the DAX-1 gene. Eur J Endocrinol; 2005 Aug;153(2):211-5
Hazardous Substances Data Bank. Corticotropin .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Corticotroph adenoma of the pituitary in a patient with X-linked adrenal hypoplasia congenita due to a novel mutation of the DAX-1 gene.
  • We report the occurrence of an ACTH-secreting adenoma in a patient with X-linked congenital adrenal hypoplasia.
  • DESIGN AND METHODS: Detailed clinical, radiological and pathological investigation of the pituitary adenoma.
  • ACTH was 24 980 pg/ml and nuclear magnetic resonance disclosed a huge pituitary adenoma.
  • Histologically, the adenoma was composed of chromophobic and basophilic neoplastic cells with positive immunostaining for ACTH.
  • CONCLUSIONS: This case suggests that in adrenal hypoplasia congenita the development of a pituitary adenoma should be considered when a sudden rise of ACTH occurs despite adequate steroid substitution.

  • Genetic Alliance. consumer health - X-linked adrenal hypoplasia congenita.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16061826.001).
  • [ISSN] 0804-4643
  • [Journal-full-title] European journal of endocrinology
  • [ISO-abbreviation] Eur. J. Endocrinol.
  • [Language] ENG
  • [Grant] Italy / Telethon / / B.38
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DAX-1 Orphan Nuclear Receptor; 0 / DNA-Binding Proteins; 0 / NR0B1 protein, human; 0 / Receptors, Retinoic Acid; 0 / Repressor Proteins; 9002-60-2 / Adrenocorticotropic Hormone
  •  go-up   go-down


29. Kageyama K, Ikeda H, Sakihara S, Nigawara T, Terui K, Tsutaya S, Matsuda E, Shoji M, Yasujima M, Suda T: A case of thyrotropin-producing pituitary adenoma, accompanied by an increase in anti-thyrotropin receptor antibody after tumor resection. J Endocrinol Invest; 2007 Dec;30(11):957-61
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of thyrotropin-producing pituitary adenoma, accompanied by an increase in anti-thyrotropin receptor antibody after tumor resection.
  • We describe a rare, but interesting, case of TSH-producing adenoma (TSHoma), accompanied by increases in both anti-TSH receptor antibody (TRAb) and thyroid-stimulating antibody (TSAb) after tumor resection.
  • A 21-yr-old woman was referred to our department for further evaluation of pituitary tumor.
  • In a nearby hospital, she had been diagnosed as having pituitary tumor.
  • On the basis of a diagnosis of pituitary adenoma with TSH production, transsphenoidal resection of the pituitary adenoma was performed.
  • [MeSH-major] Adenoma / metabolism. Antibodies, Anti-Idiotypic / blood. Pituitary Neoplasms / metabolism. Receptors, Thyrotropin / immunology. Thyrotropin / metabolism

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18250618.001).
  • [ISSN] 1720-8386
  • [Journal-full-title] Journal of endocrinological investigation
  • [ISO-abbreviation] J. Endocrinol. Invest.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Antibodies, Anti-Idiotypic; 0 / Immunoglobulins, Thyroid-Stimulating; 0 / Receptors, Thyrotropin; 0 / Thyroid Hormones; 9002-71-5 / Thyrotropin
  •  go-up   go-down


30. Ke C, Deng Z, Lei T, Zhou S, Guo DS, Wan J, Wu S: Pituitary prolactin producing adenoma with ossification: a rare histological variant and review of literature. Neuropathology; 2010 Apr;30(2):165-9
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pituitary prolactin producing adenoma with ossification: a rare histological variant and review of literature.
  • Pituitary adenoma with ossification is a rare histological variant.
  • Here a case of pituitary prolactin-producing adenoma with bone formation in a 21-year-old woman is described.
  • The cytoplasm of the adenoma cells was slightly eosinophilic and the myelo-adipose metaplastic foci were also found within the parenchyma.
  • Meanwhile, negative expressions of S-100, epithelial membrane antigen, GFAP and other pituitary hormones were also demonstrated.
  • As a rare histological variant of pituitary adenoma, the current case of pituitary prolactin producing adenoma with ossification is reported.
  • The bony shell structure may limit the growth of pituitary adenoma.
  • [MeSH-major] Ossification, Heterotopic / pathology. Pituitary Gland / pathology. Pituitary Neoplasms / pathology. Prolactinoma / pathology

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19737358.001).
  • [ISSN] 1440-1789
  • [Journal-full-title] Neuropathology : official journal of the Japanese Society of Neuropathology
  • [ISO-abbreviation] Neuropathology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  •  go-up   go-down


31. Balarini Lima GA, Machado Ede O, Dos Santos Silva CM, Filho PN, Gadelha MR: Pituitary apoplexy during treatment of cystic macroprolactinomas with cabergoline. Pituitary; 2008;11(3):287-92
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pituitary apoplexy during treatment of cystic macroprolactinomas with cabergoline.
  • Pituitary apoplexy is a rare and life-threatening clinical condition caused by hemorrhage and/or infarction of the pituitary gland or adenoma.
  • Although pituitary apoplexy is usually spontaneous, it has been associated with numerous precipitating factors, such as bromocriptine use.
  • However, reports of pituitary apoplexy during cabergoline therapy are scarce.
  • We report three patients with cystic macroprolactinomas who developed pituitary apoplexy during cabergoline treatment.
  • [MeSH-major] Antineoplastic Agents / adverse effects. Dopamine Agonists / adverse effects. Ergolines / adverse effects. Pituitary Apoplexy / chemically induced. Pituitary Neoplasms / drug therapy. Prolactinoma / drug therapy

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17570067.001).
  • [ISSN] 1386-341X
  • [Journal-full-title] Pituitary
  • [ISO-abbreviation] Pituitary
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Dopamine Agonists; 0 / Ergolines; LL60K9J05T / cabergoline
  •  go-up   go-down


32. Inagawa H, Ishizawa K, Mitsuhashi T, Shimizu M, Adachi J, Nishikawa R, Matsutani M, Hirose T: Giant invasive pituitary adenoma extending into the sphenoid sinus and nasopharynx: report of a case with intraoperative cytologic diagnosis. Acta Cytol; 2005 Jul-Aug;49(4):452-6
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant invasive pituitary adenoma extending into the sphenoid sinus and nasopharynx: report of a case with intraoperative cytologic diagnosis.
  • BACKGROUND: Invasive pituitary adenomas involving the skull base are difficult to distinguish from other, more aggressive tumors.
  • Because of the lack of endocrine abnormalities and lack of an apparent rise in pituitary hormones, preoperative diagnoses included chordoma, chondrosarcoma, meningioma and pituitary adenoma.
  • The cytologic features indicated a probable diagnosis of pituitary adenoma and excluded other possibilities.
  • Immunohistochemical demonstration of prolactin and ultrastructural features established the final diagnosis of prolactinoma.
  • As compared to frozen sections, cytologic preparations are more effective for the intraoperative diagnosis of pituitary adenomas.
  • Such neoplasms should always be included in the differential diagnosis of tumors involving the skull base.
  • [MeSH-major] Nasopharynx / pathology. Pituitary Neoplasms / diagnosis. Prolactinoma / diagnosis. Sphenoid Sinus / pathology
  • [MeSH-minor] Adult. Bromocriptine / therapeutic use. Diagnosis, Differential. Hormone Antagonists / therapeutic use. Humans. Magnetic Resonance Imaging. Male. Microscopy, Electron, Transmission. Neoplasm Invasiveness. Pituitary Gland / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16124180.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Hormone Antagonists; 3A64E3G5ZO / Bromocriptine
  •  go-up   go-down


33. Jha S, Kumar S: TSH secreting pituitary adenoma. J Assoc Physicians India; 2009 Jul;57:537-9
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] TSH secreting pituitary adenoma.
  • Thyrotropin (TSH) secreting pituitary adenomas are a very rare cause of hyperthyroidism.
  • TSH secreting tumors account for 1 percent of all pituitary adenoma.
  • They are a rare cause of thyrotoxicosis in which adenomas completely or partially lose feedback regulation of thyroid hormones and lead to sustained stimulation of thyroid gland.
  • The most definitive treatment of thyrotropin (TSH)-secreting pituitary adenomas is transsphenoidal removal of tumor after restoring euthyroidism.
  • We report a case of pituitary adenoma associated with elevated serum free thyroid hormones and non-suppressed TSH levels.
  • [MeSH-major] Adenoma / secretion. Pituitary Neoplasms / secretion. Thyrotropin / secretion
  • [MeSH-minor] Aged. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Thyroid Function Tests. Treatment Refusal

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20329419.001).
  • [ISSN] 0004-5772
  • [Journal-full-title] The Journal of the Association of Physicians of India
  • [ISO-abbreviation] J Assoc Physicians India
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 9002-71-5 / Thyrotropin
  •  go-up   go-down


34. Poggi M, Monti S, Pascucci C, Toscano V: A rare case of follicular thyroid carcinoma in a patient with thyrotropin-secreting pituitary adenoma. Am J Med Sci; 2009 Jun;337(6):462-5
MedlinePlus Health Information. consumer health - Thyroid Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A rare case of follicular thyroid carcinoma in a patient with thyrotropin-secreting pituitary adenoma.
  • OBJECTIVE: To report a rare case of a thyrotropin (TSH)-secreting pituitary adenoma associated with thyroid carcinoma.
  • METHODS: We report the clinical history, imaging studies, and laboratory and pathologic data in a male patient affected by TSH-secreting pituitary adenoma and goiter; histologic evaluation revealed thyroid carcinoma.
  • The thyroid morphologic study using Doppler ultrasonography showed a gland of increased volume with multiple nodular lesions bilaterally.
  • The nuclear magnetic resonance of the pituitary gland described a microadenoma.
  • A total thyroidectomy was performed followed by neurosurgical treatment of the pituitary lesion.
  • The patient firmly refused surgical removal of the pituitary adenoma.
  • The pituitary nuclear magnetic resonance showed a stable lesion without difference in size.
  • CONCLUSION: The clinical association between thyroid carcinoma and TSH-producing adenoma is rare, with the removal of the pituitary lesion being mandatory.
  • Pituitary surgery, in this case, is impossible, showing that TSH-producing microadenoma could seldom have an indolent behavior.
  • [MeSH-major] Adenoma / complications. Pituitary Neoplasms / complications. Thyroid Neoplasms / complications. Thyrotropin / secretion

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19390430.001).
  • [ISSN] 0002-9629
  • [Journal-full-title] The American journal of the medical sciences
  • [ISO-abbreviation] Am. J. Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 9002-71-5 / Thyrotropin
  •  go-up   go-down


35. Elston MS, Conaglen JV: Clinical and biochemical characteristics of patients with thyroid-stimulating hormone-secreting pituitary adenomas from one New Zealand centre. Intern Med J; 2010 Mar;40(3):214-9
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical and biochemical characteristics of patients with thyroid-stimulating hormone-secreting pituitary adenomas from one New Zealand centre.
  • BACKGROUND: Thyroid-stimulating hormone (TSH)-secreting pituitary adenomas (TSHoma) are a rare cause of thyrotoxicosis and need to be distinguished from the syndrome of resistance to thyroid hormone.
  • Patients with TSHoma may also be misdiagnosed as having primary hyperthyroidism and receive inappropriate treatment directed towards the thyroid gland.
  • The median age at presentation was 43 years and the median time from symptom onset to correct diagnosis was 3 years (range 0.25-12 years).
  • Five patients had a macroadenoma at the time of diagnosis.
  • Three patients received octreotide as primary treatment with two of these patients later undergoing transsphenoidal resection of the pituitary adenoma.
  • CONCLUSION: With increased awareness and earlier diagnosis of TSH-secreting pituitary adenomas, management can be appropriately directed towards the pituitary.
  • [MeSH-major] Adenoma / secretion. Adenoma / therapy. Hospitals, Special. Pituitary Neoplasms / secretion. Pituitary Neoplasms / therapy. Thyrotropin / secretion

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19849747.001).
  • [ISSN] 1445-5994
  • [Journal-full-title] Internal medicine journal
  • [ISO-abbreviation] Intern Med J
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 9002-71-5 / Thyrotropin
  •  go-up   go-down


36. Pawlikowski M, Kunert-Radek J, Radek M: Plurihormonality of pituitary adenomas in light of immunohistochemical studies. Endokrynol Pol; 2010 Jan-Feb;61(1):63-6
Hazardous Substances Data Bank. MENOTROPINS .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Plurihormonality of pituitary adenomas in light of immunohistochemical studies.
  • INTRODUCTION: Plurihormonality of pituitary adenomas can be defined as the ability of an adenoma to express more than one pituitary hormone.
  • The application of immunohistochemistry to diagnose surgically removed pituitary tumours revealed that a great number of pituitary adenomas are in fact plurihormonal.
  • However, data on the incidence and the clinical relevance of the pituitary adenoma plurihormonality are still scarce and controversial.
  • MATERIAL AND METHODS: Hundred fifty-five pituitary adenomas, surgically removed, were studied immunohistochemically with the antibodies against pituitary hormones or their subunits.
  • Additionally, 40 adenomas were immunostained with Ki-67 antibody to evaluate the proliferative potential.
  • Even with this limitation, plurihormonality was found to be a frequent finding in both hormonally active and clinically non-functioning pituitary adenomas.
  • It was shown that over one-third (36.1%) of the investigated adenomas expressed more than one hormone.
  • Plurihormonal adenomas also possess higher Ki-67 indices, as compared to monohormonal tumours.
  • CONCLUSIONS: Plurihormonality is a frequent phenomenon in both hormonally active and clinically non-functioning pituitary adenomas.
  • [MeSH-major] Adenoma / metabolism. Neoplasm Recurrence, Local / metabolism. Pituitary Hormones / metabolism. Pituitary Neoplasms / metabolism
  • [MeSH-minor] Adrenocorticotropic Hormone / metabolism. Follicle Stimulating Hormone / metabolism. Human Growth Hormone / metabolism. Humans. Immunohistochemistry. Ki-67 Antigen / metabolism. Luteinizing Hormone / metabolism. Pituitary ACTH Hypersecretion / complications. Pituitary ACTH Hypersecretion / metabolism. Prolactin / metabolism

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • Hazardous Substances Data Bank. Corticotropin .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20205106.001).
  • [ISSN] 0423-104X
  • [Journal-full-title] Endokrynologia Polska
  • [ISO-abbreviation] Endokrynol Pol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Ki-67 Antigen; 0 / Pituitary Hormones; 12629-01-5 / Human Growth Hormone; 9002-60-2 / Adrenocorticotropic Hormone; 9002-62-4 / Prolactin; 9002-67-9 / Luteinizing Hormone; 9002-68-0 / Follicle Stimulating Hormone
  •  go-up   go-down


37. Norberg L, Johansson R, Rasmuson T: Intracranial tumours after external fractionated radiotherapy for pituitary adenomas in northern Sweden. Acta Oncol; 2010 Nov;49(8):1276-82
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intracranial tumours after external fractionated radiotherapy for pituitary adenomas in northern Sweden.
  • We analysed the incidence of second primary intracranial tumours in patients with pituitary adenomas treated with radiotherapy compared to the risk of patients not exposed to irradiation and to the general population.
  • MATERIALS AND METHODS: This retrospective cohort study includes 298 patients with pituitary adenomas that received radiotherapy to the pituitary from 1960 to 2007.
  • Only patients with ≥12 months follow-up after diagnosis of pituitary adenoma were included.
  • A cohort of 131 patients with pituitary adenomas not treated with radiotherapy was used as reference.
  • RESULTS: The median observation time after diagnosis of pituitary adenoma in 298 patients treated with radiotherapy was 14 years, and the total number of person-years at risk was 4 784.
  • DISCUSSION: The results indicate an increased risk of second primary intracranial tumours in patients treated with radiotherapy for pituitary adenomas, compared to patients not exposed to irradiation and to the general population.
  • [MeSH-major] Adenoma / radiotherapy. Brain Neoplasms / epidemiology. Neoplasms, Radiation-Induced / epidemiology. Neoplasms, Second Primary / epidemiology. Pituitary Neoplasms / radiotherapy

  • MedlinePlus Health Information. consumer health - Brain Tumors.
  • MedlinePlus Health Information. consumer health - Childhood Brain Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20429723.001).
  • [ISSN] 1651-226X
  • [Journal-full-title] Acta oncologica (Stockholm, Sweden)
  • [ISO-abbreviation] Acta Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  •  go-up   go-down


38. Kim JP, Park BJ, Kim SB, Lim YJ: Pituitary Apoplexy due to Pituitary Adenoma Infarction. J Korean Neurosurg Soc; 2008 May;43(5):246-9
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pituitary Apoplexy due to Pituitary Adenoma Infarction.
  • Cause of pituitary apoplexy has been known as hemorrhage, hemorrhagic infarction or infarction of pituitary adenoma or adjacent tissues of pituitary gland.
  • However, pituitary apoplexy caused by pure infarction of pituitary adenoma has been rarely reported.
  • Here, we present the two cases pituitary apoplexies caused by pituitary adenoma infarction that were confirmed by transsphenoidal approach (TSA) and pathologic reports.
  • Pathologic report of first case revealed total tumor infarction of a nonfunctioning pituitary macroadenoma and second case partial tumor infarction of ACTH secreting pituitary macroadenoma.
  • Patients with pituitary apoplexy which was caused by pituitary adenoma infarction unrelated to hemorrhage or hemorrhagic infarction showed good response to TSA treatment.
  • Further study on the predisposing factors of pituitary apoplexy and the mechanism of infarction in pituitary adenoma is necessary.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] AJNR Am J Neuroradiol. 2007 Nov-Dec;28(10):2023-9 [17898201.001]
  • [Cites] J Neurol Neurosurg Psychiatry. 2001 Oct;71(4):542-5 [11561045.001]
  • [Cites] J Neurosurg. 2006 Jun;104(6):931-7 [16776337.001]
  • [Cites] J Neurosurg. 2006 Jun;104(6):892-8 [16776332.001]
  • [Cites] Pituitary. 2005;8(2):81-7 [16195779.001]
  • [Cites] Medicine (Baltimore). 2005 May;84(3):188-96 [15879908.001]
  • [Cites] Neurosurgery. 2005;56(1):65-72; discussion 72-3 [15617587.001]
  • [Cites] J Clin Endocrinol Metab. 2004 Nov;89(11):5649-54 [15531524.001]
  • [Cites] J Neurosurg. 1950 Sep;7(5):421-39 [14774761.001]
  • [Cites] Acta Anaesthesiol Scand. 1999 Feb;43(2):236-8 [10027037.001]
  • [Cites] Endocr J. 1999 Feb;46(1):147-51 [10426579.001]
  • [Cites] Postgrad Med J. 1996 Mar;72(845):172-3 [8731710.001]
  • [Cites] Neurosurgery. 1984 Mar;14(3):363-73 [6369168.001]
  • [Cites] J Neurosurg. 1981 Aug;55(2):187-93 [7252541.001]
  • [Cites] AJNR Am J Neuroradiol. 2002 Aug;23(7):1240-5 [12169486.001]
  • [Cites] Endocr J. 2001 Aug;48(4):493-8 [11603573.001]
  • [Cites] J Clin Neurosci. 2006 Dec;13(10):1057-62 [17071092.001]
  • (PMID = 19096606.001).
  • [ISSN] 2005-3711
  • [Journal-full-title] Journal of Korean Neurosurgical Society
  • [ISO-abbreviation] J Korean Neurosurg Soc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2588219
  • [Keywords] NOTNLM ; Pituitary adenoma infarction / Pituitary apoplexy
  •  go-up   go-down


39. Steele CA, MacFarlane IA, Blair J, Cuthbertson DJ, Didi M, Mallucci C, Javadpour M, Daousi C: Pituitary adenomas in childhood, adolescence and young adulthood: presentation, management, endocrine and metabolic outcomes. Eur J Endocrinol; 2010 Oct;163(4):515-22
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pituitary adenomas in childhood, adolescence and young adulthood: presentation, management, endocrine and metabolic outcomes.
  • OBJECTIVE: To elucidate the long-term outcomes of pituitary adenomas diagnosed in childhood and adolescence, knowledge of which remains sparse.
  • DESIGN AND METHODS: A retrospective review of patients aged ≤21 years at diagnosis of pituitary adenoma, attending a neuroendocrine service in Liverpool, UK, between 1984-2009.
  • RESULTS: There were 41 patients (33 female), mean age at diagnosis 17.3 years (range 11-21) and mean follow-up 9.6 years; 29 patients had prolactinomas (15 macroprolactinomas), 6 non-functioning pituitary adenomas (NFPAs), 5 Cushing's disease (CD) and 1 acromegaly.
  • All prolactinoma patients received dopamine agonists (DAs) and three also underwent pituitary surgery.
  • Thirteen patients gained significant weight (body mass index (BMI) increase >2 kg/m(2)) since diagnosis and 16 in total are now obese (BMI>30 kg/m(2)).
  • CONCLUSIONS: This is one of the largest reviews of patients aged 21 or younger at diagnosis of pituitary adenoma followed up by a single service.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20685833.001).
  • [ISSN] 1479-683X
  • [Journal-full-title] European journal of endocrinology
  • [ISO-abbreviation] Eur. J. Endocrinol.
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Dopamine Agonists
  •  go-up   go-down


40. Ebner FH, Hauser TK, Honegger J: SIADH following pituitary adenoma apoplexy. Neurol Sci; 2010 Apr;31(2):217-8
Hazardous Substances Data Bank. SODIUM .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] SIADH following pituitary adenoma apoplexy.
  • The rare case of a patient with SIADH following pituitary adenoma apoplexy is reported.
  • Since apoplexy did not exert any mass effect on surrounding structures, the patient was treated conservatively and the anterior pituitary gland insufficiency has been substituted adequately.
  • Diagnosis of SIADH was made.
  • It is essential to be aware of this rare syndrome in patients with pituitary adenoma apoplexy.
  • [MeSH-major] Inappropriate ADH Syndrome / complications. Pituitary Apoplexy / complications. Pituitary Neoplasms / complications
  • [MeSH-minor] Aged, 80 and over. Humans. Magnetic Resonance Imaging. Male. Pituitary Gland / pathology. Sodium / blood. Time Factors

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20119738.001).
  • [ISSN] 1590-3478
  • [Journal-full-title] Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
  • [ISO-abbreviation] Neurol. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 9NEZ333N27 / Sodium
  •  go-up   go-down


41. Ma J, Qiao M, Li L, Hu W: [Endoscopic transseptal transsphenoidal pituitary adenoma microsurgery]. Lin Chuang Er Bi Yan Hou Ke Za Zhi; 2006 Jan;20(2):58-9, 63
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Endoscopic transseptal transsphenoidal pituitary adenoma microsurgery].
  • OBJECTIVE: To introduce the approach and technique of endoscopic transseptal transsphenoidal pituitary adenoma microsurgery.
  • METHOD: Endoscopic transseptal transsphenoidal pituitary adenoma microsurgery were performed in 23 patients.
  • CONCLUSION: Compared with transsphenoidal pituitary adenoma microsurgery and endoscopic transsphenoidal pituitary adenoma surgery, endoscopic transseptal transsphenoidal pituitary adenoma microsurgery could combine the benefits of the two approaches.
  • [MeSH-major] Hypophysectomy / methods. Nasal Septum / surgery. Pituitary Neoplasms / surgery. Sphenoid Sinus / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16570813.001).
  • [Journal-full-title] Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology
  • [ISO-abbreviation] Lin Chuang Er Bi Yan Hou Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] China
  •  go-up   go-down


42. Lindholm J, Nielsen EH, Bjerre P, Christiansen JS, Hagen C, Juul S, Jørgensen J, Kruse A, Laurberg P, Stochholm K: Hypopituitarism and mortality in pituitary adenoma. Clin Endocrinol (Oxf); 2006 Jul;65(1):51-8
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hypopituitarism and mortality in pituitary adenoma.
  • BACKGROUND AND OBJECTIVE: Previous studies on hypopituitarism and mortality have concluded that insufficient pituitary function is associated with decreased survival.
  • The purpose was to assess the relationship between mortality and pituitary function.
  • PATIENTS AND DESIGN: One hundred and sixty consecutive patients (99 men and 61 women) with functionless, suprasellar pituitary adenoma.
  • RESULTS: Postoperatively 30% of the patients had normal pituitary function (normal adrenocortical, thyroid and gonadal function), 26% were panhypopituitary and 36% had partial pituitary insufficiency.
  • SMR in patients with normal pituitary function, panhypopituitarism and partial insufficiency were not different from that in the general population.
  • SMR in hypopituitary women was substantially higher than in men with pituitary insufficiency.
  • CONCLUSION: Pituitary surgery for nonfunctioning adenoma and subsequent pituitary insufficiency had no effect on mortality in men, but was associated with significantly increased mortality in women.
  • [MeSH-major] Adenoma / mortality. Hypopituitarism / mortality. Pituitary Neoplasms / mortality

  • Genetic Alliance. consumer health - Hypopituitarism.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16817819.001).
  • [ISSN] 0300-0664
  • [Journal-full-title] Clinical endocrinology
  • [ISO-abbreviation] Clin. Endocrinol. (Oxf)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 9002-72-6 / Growth Hormone
  •  go-up   go-down


43. Clarke MJ, Erickson D, Castro MR, Atkinson JL: Thyroid-stimulating hormone pituitary adenomas. J Neurosurg; 2008 Jul;109(1):17-22
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Thyroid-stimulating hormone pituitary adenomas.
  • OBJECT: Thyroid-stimulating hormone (TSH)-secreting pituitary adenomas are rare, representing < 2% of all pituitary adenomas.
  • METHODS: The authors conducted a retrospective analysis of patients with TSH-secreting or clinically silent TSH-immunostaining pituitary tumors among all pituitary adenomas followed at their institution between 1987 and 2003.
  • Of these, 10 patients had a history of clinical hyperthyroidism, of whom 7 had undergone ablative thyroid procedures (thyroid surgery/(131)I ablation) prior to the diagnosis of pituitary adenoma.
  • Patients with TSH-secreting tumors were defined as in remission after surgery if they had no residual adenoma on imaging and had biochemical evidence of hypo-or euthyroidism.
  • Eleven patients (61%) ultimately required thyroid hormone replacement therapy, and 5 (24%) required additional pituitary hormone replacement.
  • Of these, 2 patients required treatment for new anterior pituitary dysfunction as a complication of surgery, and 2 patients with preoperative partial anterior pituitary dysfunction developed complete panhypopituitarism.
  • The remainder had no change in pituitary function from their preoperative state.
  • CONCLUSIONS: Thyroid-stimulating hormone-secreting pituitary lesions are often delayed in diagnosis, are frequently macroadenomas and plurihormonal in terms of their pathological characteristics, have a heterogeneous clinical picture, and are difficult to treat.
  • [MeSH-major] Adenoma / diagnosis. Adenoma / surgery. Pituitary Neoplasms / diagnosis. Pituitary Neoplasms / surgery. Thyrotropin / secretion

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18590428.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 9002-71-5 / Thyrotropin
  •  go-up   go-down


44. Miyakoshi T, Takei M, Kajiya H, Egashira N, Takekoshi S, Teramoto A, Osamura RY: Expression of Wnt4 in human pituitary adenomas regulates activation of the beta-catenin-independent pathway. Endocr Pathol; 2008;19(4):261-73
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of Wnt4 in human pituitary adenomas regulates activation of the beta-catenin-independent pathway.
  • A member of the Wnt family of genes, Wnt4, has been known to regulate proliferation of anterior pituitary cell types in the mouse during embryonic development.
  • In order to elucidate the roles of Wnt signaling in human pituitary adenomas, we examined the expression of Wnt4 and its putative receptor Frizzled6 (Fzd6) by immunohistochemistry in pituitary adenomas and normal pituitaries.
  • Expression of Wnt4 was higher in growth hormone-producing adenomas (GHomas), prolactin-producing adenomas (PRLomas), and thyroid-stimulating hormone-producing adenomas (TSHomas) than in the normal pituitary.
  • Fzd6 was widely expressed in GHomas, PRLomas, TSHomas, and gonadotropin subunit (GnSU)-positive adenomas.
  • In normal pituitary glands, Wnt4 and Fzd6 were colocalized predominantly in follicle-stimulating hormone-, luteinizing hormone-, and alpha-subunits of glycoprotein hormone-positive cells.
  • The canonical Wnt/beta-catenin signaling pathway was analyzed by beta-catenin immunohistochemistry. beta-Catenin was localized at the cell membrane in all pituitary adenomas, but not in the nuclei.
  • These results suggested that activation of Wnt4/Fzd6 signaling through a "beta-catenin-independent" pathway played a role in proliferation and survival of the pituitary adenoma cells.
  • [MeSH-major] Adenoma / metabolism. Biomarkers, Tumor / metabolism. Pituitary Neoplasms / metabolism. Wnt Proteins / metabolism. beta Catenin / metabolism
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Fluorescent Antibody Technique, Indirect. Frizzled Receptors / genetics. Frizzled Receptors / metabolism. Gene Expression Profiling. Gene Expression Regulation, Neoplastic. Humans. Immunoenzyme Techniques. Male. Middle Aged. Pituitary Gland / metabolism. Receptors, G-Protein-Coupled / genetics. Receptors, G-Protein-Coupled / metabolism. Signal Transduction / genetics. Wnt4 Protein. Young Adult

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • Guide to Pharmacology. gene/protein/disease-specific - FZD6 - data and references .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19034702.001).
  • [ISSN] 1046-3976
  • [Journal-full-title] Endocrine pathology
  • [ISO-abbreviation] Endocr. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CTNNB1 protein, human; 0 / FZD6 protein, human; 0 / Frizzled Receptors; 0 / Receptors, G-Protein-Coupled; 0 / WNT4 protein, human; 0 / Wnt Proteins; 0 / Wnt4 Protein; 0 / Wnt4 protein, mouse; 0 / beta Catenin
  •  go-up   go-down


45. Pollard RE, Reilly CM, Uerling MR, Wood FD, Feldman EC: Cross-sectional imaging characteristics of pituitary adenomas, invasive adenomas and adenocarcinomas in dogs: 33 cases (1988-2006). J Vet Intern Med; 2010 Jan-Feb;24(1):160-5
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cross-sectional imaging characteristics of pituitary adenomas, invasive adenomas and adenocarcinomas in dogs: 33 cases (1988-2006).
  • BACKGROUND: Pituitary tumors in dogs can be adenomas, invasive adenomas, or adenocarcinomas.
  • In people, invasive adenomas and pituitary adenocarcinomas carry a worse prognosis than adenomas.
  • HYPOTHESIS/OBJECTIVE: To identify differentiating features on cross-sectional imaging in dogs with pituitary adenomas, invasive adenomas, and adenocarcinomas.
  • ANIMALS: Thirty-three dogs that had computed tomography (CT) or magnetic resonance imaging (MRI) performed and a necropsy diagnosis of pituitary adenoma (n = 20), invasive adenoma (n = 11), or adenocarcinoma (n = 2).
  • METHODS: Medical records were retrospectively reviewed for signalment, history, and diagnosis.
  • CT and MR images were reviewed for characteristics of pituitary tumors.
  • RESULTS: Mean (+/- standard deviation) age for dogs with pituitary adenomas (10.6 +/- 2.9 years) was greater than that of those with invasive adenomas (8.3 +/- 2.7 years, P = .04).
  • Eighteen out of 20 (90%) dogs with adenomas had contrast-enhancing masses.
  • Mean adenoma height was 1.2 +/- 0.7cm.
  • Eight out of 20 (40%) adenomas were round and 8/20 (40%) compressed surrounding brain.
  • Eleven out of 11 dogs (100%) with invasive adenomas had contrast-enhancing masses.
  • Mean invasive adenoma height was 1.8 +/- 0.7 cm, which was significantly greater than adenomas (P = .03).
  • CONCLUSIONS AND CLINICAL RELEVANCE: Invasive adenoma should be suspected if a dog with a pituitary tumor is <7.7 years of age and has a mass > 1.9 cm in vertical height.

  • MedlinePlus Health Information. consumer health - CT Scans.
  • MedlinePlus Health Information. consumer health - MRI Scans.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19925577.001).
  • [ISSN] 0891-6640
  • [Journal-full-title] Journal of veterinary internal medicine
  • [ISO-abbreviation] J. Vet. Intern. Med.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
  •  go-up   go-down


46. Losa M, Mortini P, Minelli R, Giovanelli M: Coexistence of TSH-secreting pituitary adenoma and autoimmune hypothyroidism. J Endocrinol Invest; 2006 Jun;29(6):555-9
Hazardous Substances Data Bank. LEVOTHYROXINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Coexistence of TSH-secreting pituitary adenoma and autoimmune hypothyroidism.
  • OBJECTIVE: TSH-secreting pituitary adenomas account for about 1-2% of all pituitary adenomas.
  • Their diagnosis may be very difficult when coexistence of other diseases masquerades the clinical and biochemical manifestations of TSH-hypersecretion.
  • Eight yr before, the patient had been given a diagnosis of subclinical autoimmune hypothyroidism because of slightly elevated TSH levels and low-normal free T4 (FT4).
  • Gonadotropins were normal, whereas PRL level was elevated at 70 microg/l and magnetic resonance imaging (MRI) of the hypothalamic- pituitary region revealed a pituitary lesion with slight suprasellar extension.
  • The tumor was surgically removed and histological examinations revealed a pituitary adenoma strongly positive for TSH.
  • MRI of the hypothalamic-pituitary region showed no evidence of residual tumor.
  • CONCLUSIONS: Coexistence of autoimmune hypothyroidism and TSH-secreting pituitary adenoma may cause further delays in the diagnosis of the latter.
  • In patients with autoimmune hypothyroidism, one should be aware of the possible presence of a TSH-secreting pituitary adenoma when TSH levels do not adequately suppress in the face of high doses of L-T4 replacement therapy and elevated serum thyroid hormone levels.
  • [MeSH-major] Adenoma / complications. Adenoma / secretion. Autoimmune Diseases / complications. Hypothyroidism / complications. Pituitary Neoplasms / complications. Pituitary Neoplasms / secretion. Thyrotropin / secretion

  • MedlinePlus Health Information. consumer health - Autoimmune Diseases.
  • MedlinePlus Health Information. consumer health - Hypothyroidism.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16840835.001).
  • [ISSN] 0391-4097
  • [Journal-full-title] Journal of endocrinological investigation
  • [ISO-abbreviation] J. Endocrinol. Invest.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 9002-71-5 / Thyrotropin; Q51BO43MG4 / Thyroxine
  •  go-up   go-down


47. Scheithauer BW, Silva AI, Atkinson JL, Nippoldt TB, Kaufmann TJ, Kovacs K, Horvath E, Lloyd R: Pituitary adenoma with tumoral granulomatous reaction. Endocr Pathol; 2007;18(2):86-90
Hazardous Substances Data Bank. TESTOSTERONE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pituitary adenoma with tumoral granulomatous reaction.
  • Herein, we report a unique case of an adult male with a corticotrophic pituitary adenoma of silent subtype 1 exhibiting conspicuous idiopathic tumoral noncaseating granulomatous inflammation.
  • [MeSH-major] ACTH-Secreting Pituitary Adenoma / pathology. Adenoma / pathology. Granuloma / pathology. Pituitary Neoplasms / pathology
  • [MeSH-minor] Blood Pressure. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Male. Microscopy, Electron. Middle Aged. Pituitary Hormones / blood. Reverse Transcriptase Polymerase Chain Reaction. Testosterone / blood. Thyrotropin / blood. Thyroxine / blood. Vision Disorders / etiology

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • Hazardous Substances Data Bank. LEVOTHYROXINE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17916998.001).
  • [ISSN] 1046-3976
  • [Journal-full-title] Endocrine pathology
  • [ISO-abbreviation] Endocr. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Pituitary Hormones; 3XMK78S47O / Testosterone; 9002-71-5 / Thyrotropin; Q51BO43MG4 / Thyroxine
  •  go-up   go-down


48. Zatelli MC, degli Uberti EC: MicroRNAs and possible role in pituitary adenoma. Semin Reprod Med; 2008 Nov;26(6):453-60
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] MicroRNAs and possible role in pituitary adenoma.
  • This review reports the current knowledge of microRNA (miRNA) expression in pituitary adenomas, focusing on recent microarray data.
  • Moreover, a discussion is provided concerning the possible role of validated and putative targets of the most dysregulated miRNA in pituitary adenoma pathogenesis.
  • [MeSH-major] Adenoma / genetics. MicroRNAs / physiology. Pituitary Neoplasms / genetics

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18951327.001).
  • [ISSN] 1526-4564
  • [Journal-full-title] Seminars in reproductive medicine
  • [ISO-abbreviation] Semin. Reprod. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / MicroRNAs
  • [Number-of-references] 59
  •  go-up   go-down


49. Zhong J, Li ST, Yao XH, Jin B, Wan L: An intrasellar rhabdomyosarcoma misdiagnosed as pituitary adenoma. Surg Neurol; 2007;68 Suppl 2:S29-33; discussion S33
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An intrasellar rhabdomyosarcoma misdiagnosed as pituitary adenoma.
  • The patient was preoperatively diagnosed as pituitary adenoma, which was confirmed pathologically as rhabdomyosarcoma after the operation.
  • CONCLUSIONS: Our findings suggest that rhabdomyosarcoma should be considered in the differential diagnosis of a primary intrasellar neoplasm.
  • [MeSH-major] Adenoma / diagnosis. Diagnostic Errors. Pituitary Neoplasms / diagnosis. Rhabdomyosarcoma / diagnosis. Sella Turcica. Skull Neoplasms / diagnosis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18037040.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


50. Oyama K, Yamada S, Usui M, Kovacs K: Sellar neuroblastoma mimicking pituitary adenoma. Pituitary; 2005;8(2):109-14
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sellar neuroblastoma mimicking pituitary adenoma.
  • We present a neuroblastoma that arose in the sellar region and mimicked a non-functioning pituitary adenoma.
  • MRI showed a sellar mass with suprasellar extension mimicking a pituitary adenoma.
  • Detailed histologic examination confirmed the diagnosis of neuroblastoma.
  • CONCLUSION: Neuroblastoma should be considered in the differential diagnosis of patients with sellar lesions.
  • [MeSH-major] Neuroblastoma / diagnosis. Pituitary Neoplasms / diagnosis
  • [MeSH-minor] Adenoma / diagnosis. Adult. Diagnosis, Differential. Humans. Male. Neoplasm Recurrence, Local / radiotherapy. Neoplasm Recurrence, Local / surgery

  • Genetic Alliance. consumer health - Neuroblastoma.
  • MedlinePlus Health Information. consumer health - Neuroblastoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16501893.001).
  • [ISSN] 1386-341X
  • [Journal-full-title] Pituitary
  • [ISO-abbreviation] Pituitary
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


51. Hong J, Ding X, Lu Y: Clinical analysis of 103 elderly patients with pituitary adenomas: transsphenoidal surgery and follow-up. J Clin Neurosci; 2008 Oct;15(10):1091-5
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical analysis of 103 elderly patients with pituitary adenomas: transsphenoidal surgery and follow-up.
  • Our objective was to study the single-center clinical diagnosis and surgical treatment of pituitary adenomas in elderly patients.
  • A retrospective single-center study was performed on 103 patients aged 65 years and over with a diagnosis of pituitary adenoma and with a mean follow-up duration of 6.1+/-1.3 years.
  • The findings of this analysis support the use of TSS as a feasible treatment for pituitary adenomas in elderly patients.
  • [MeSH-major] Neoplasm Recurrence, Local / surgery. Neurosurgical Procedures / methods. Pituitary Neoplasms / surgery. Sphenoid Sinus / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18693113.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
  •  go-up   go-down


52. Wolffenbuttel BH, van den Berg G, Hoving EW, van der Klauw MM: [The natural course of non-functioning pituitary adenomas]. Ned Tijdschr Geneeskd; 2008 Nov 22;152(47):2537-43
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The natural course of non-functioning pituitary adenomas].
  • [Transliterated title] Het natuurlijke beloop van het niet-functionerende hypofyseadenoom.
  • 3 patients presented with non-functioning pituitary adenomas: a 50-year-old woman who had an adenoma that had not increased in size for 3 years; a 68-year-old man with an adenoma that was undiagnosed for 5 years and led to pituitary insufficiency and bitemporal hemianopsia; and a 64-year-old woman, who had refused therapy and follow-up after diagnosis of the adenoma 20 years earlier.
  • She was admitted with a hydrocephalus, pituitary insufficiency, and severe visual loss.
  • The clinical symptoms of pituitary adenomas are caused by the mass effects of the tumour and may vary considerably between patients.
  • The natural course of these adenomas is such that lifelong follow-up is necessary.
  • [MeSH-major] Adenoma / pathology. Pituitary Neoplasms / pathology. Quality of Life

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentOn] Ned Tijdschr Geneeskd. 2008 Nov 22;152(47):2565-70 [19174939.001]
  • (PMID = 19174932.001).
  • [ISSN] 0028-2162
  • [Journal-full-title] Nederlands tijdschrift voor geneeskunde
  • [ISO-abbreviation] Ned Tijdschr Geneeskd
  • [Language] dut
  • [Publication-type] Case Reports; Comment; English Abstract; Journal Article
  • [Publication-country] Netherlands
  •  go-up   go-down


53. Kurtulmus N, Turkmen C, Yarman S, Tokmak H, Mudun A: The value of Tc-99m tetrofosmin in the imaging of pituitary adenomas. J Endocrinol Invest; 2007 Feb;30(2):86-90
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The value of Tc-99m tetrofosmin in the imaging of pituitary adenomas.
  • AIM: Magnetic resonance imaging (MRI) and computerized tomography (CT) are used in the diagnosis and follow-up of pituitary adenoma cases.
  • It has been shown that some radionuclides were taken up by the pituitary adenomas.
  • The aim of this study was to evaluate the uptake of the technetium-99m (Tc-99m) tetrofosmin (TF) in the pituitary adenoma and normal pituitary tissue and assess the ability of Tc-99m TF to predict tumor malignancy in pituitary gland.
  • METHODS: The patients with pituitary adenoma (7 invasive and 8 non-invasive) were compared with control group (no. 13).
  • Single-photon emission computed tomography (SPECT) imaging of pituitary gland was performed in both groups.
  • RESULTS: The average tetrofosmin uptake index of pituitary adenoma is 2.44+/-1.54 for the patients and 1.69+/-0.71 for the control group.
  • The average index was calculated as 3.04+/-2.15 for invasive adenomas and 1.92+/-0.33 for the non-invasive group, and there was no significant difference between the two groups regarding uptake of the agent (p 0.53).
  • Furthermore, it was determined that the invasive and non-invasive adenomas displayed an uptake of Tc-99m TF similar to normal pituitary tissue.
  • CONCLUSIONS: Since the pituitary adenoma and normal pituitary tissue gave similar results regarding Tc-99m TF uptake, it was concluded that this agent would not be useful in the diagnosis of pituitary adenoma.
  • [MeSH-major] Organophosphorus Compounds. Organotechnetium Compounds. Pituitary Neoplasms / radionuclide imaging. Tomography, Emission-Computed, Single-Photon / methods
  • [MeSH-minor] Adult. Aged. Female. Humans. Male. Middle Aged. Pituitary Gland / metabolism. Pituitary Gland / radionuclide imaging

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17392596.001).
  • [ISSN] 1720-8386
  • [Journal-full-title] Journal of endocrinological investigation
  • [ISO-abbreviation] J. Endocrinol. Invest.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Organophosphorus Compounds; 0 / Organotechnetium Compounds; 0 / technetium Tc 99m 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane
  •  go-up   go-down


54. Kim HC, Kang SG, Huh PW, Yoo do S, Cho KS, Kim DS: Pituitary abscess in a pregnant woman. J Clin Neurosci; 2007 Nov;14(11):1135-9
MedlinePlus Health Information. consumer health - Pituitary Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pituitary abscess in a pregnant woman.
  • Pituitary abscess is a rare and potentially lethal condition.
  • Pituitary abscess in a pregnant woman has not been previously described.
  • A 38-year-old pregnant woman (34 weeks gestation) with a pituitary mass complained of a progressive headache and sudden visual impairment.
  • On MRI, the preoperative diagnosis was pituitary adenoma with sphenoid sinusitis.
  • She underwent an uncomplicated transsphenoidal procedure for removal of the pituitary mass.
  • To our knowledge this is the first case of pituitary abscess reported during pregnancy.
  • [MeSH-major] Brain Abscess / microbiology. Brain Abscess / surgery. Pituitary Diseases / microbiology. Pituitary Diseases / surgery. Pregnancy Complications, Infectious

  • MedlinePlus Health Information. consumer health - Infections and Pregnancy.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17420130.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
  •  go-up   go-down


55. Santos J, Paiva I, Gomes L, Batista C, Geraldes E, Rito M, Velez A, Oliveira F, Carvalheiro M: [Recurrent hypercortisolism after removal of an ACTH secretor pituitary adenoma associated with an adrenal macronodule]. Acta Med Port; 2010 Jan-Feb;23(1):107-12
MedlinePlus Health Information. consumer health - Cushing's Syndrome.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Recurrent hypercortisolism after removal of an ACTH secretor pituitary adenoma associated with an adrenal macronodule].
  • [Transliterated title] Hipercortisolismo recorrente após remoção de adenoma hipofisário secretor de ACTH associado a macronódulo da glândula supra-renal.
  • Laboratorial study: High urinary free cortisol (UFC); serum cortisol - 25 microg/dl (8 am) (5-25) and 20 microg/dL (11pm); ACTH - 20 pg/mL (9-52) (8 am) and 14 pg/mL (11 pm); serum cortisol after dexamethasone suppression test: 14,9 mg/dL; CRH test: elevation of ACTH; Pituitary MRI: microadenoma; abdominal CT: nodule on the left adrenal.
  • [MeSH-major] ACTH-Secreting Pituitary Adenoma / complications. ACTH-Secreting Pituitary Adenoma / surgery. Adenoma / complications. Adenoma / surgery. Adrenal Gland Neoplasms / complications. Cushing Syndrome / etiology. Cushing Syndrome / surgery

  • MedlinePlus Health Information. consumer health - Adrenal Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20353713.001).
  • [ISSN] 1646-0758
  • [Journal-full-title] Acta médica portuguesa
  • [ISO-abbreviation] Acta Med Port
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Portugal
  •  go-up   go-down


56. Nielsen EH, Lindholm J, Bjerre P, Christiansen JS, Hagen C, Juul S, Jørgensen J, Kruse A, Laurberg P: Frequent occurrence of pituitary apoplexy in patients with non-functioning pituitary adenoma. Clin Endocrinol (Oxf); 2006 Mar;64(3):319-22
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Frequent occurrence of pituitary apoplexy in patients with non-functioning pituitary adenoma.
  • BACKGROUND AND OBJECTIVE: There is agreement in the literature that pituitary apoplexy is a rare disorder.
  • As our experience differs from this view, we analysed the incidence in patients operated on for a nonfunctioning pituitary adenoma.
  • PATIENTS AND DESIGN: One hundred ninety-two consecutive patients with a suprasellar, clinically inactive adenoma operated on during the period 1985-1996 were retrospectively reviewed.
  • A diagnosis of pituitary apoplexy was made from relevant neurological symptoms together with pertinent findings at operation.
  • RESULTS: Pituitary apoplexy occurred in 41 patients (21%), in 23 patients within 12 days prior to the operation.
  • During this period, 12 patients had died, yielding a standard mortality ratio of 1.09 (95% CI 0.62-1.92), similar to that in the patients who had not sustained pituitary apoplexy.
  • Postoperatively, 24% of the patients had normal pituitary function, 38% were panhypopituitary and partial pituitary insufficiency was present in 38%.
  • CONCLUSION: Most of our findings add little to what is known about pituitary apoplexy.
  • We found a much higher incidence of pituitary apoplexy despite rather rigorous criteria for the diagnosis.
  • The outcome as regards survival and endocrine function was not different from that in patients with a nonfunctioning adenoma who did not suffer pituitary apoplexy.
  • [MeSH-major] Adenoma / complications. Pituitary Apoplexy / etiology. Pituitary Neoplasms / complications
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Male. Middle Aged. Pituitary Gland / physiopathology. Postoperative Period. Prognosis. Retrospective Studies

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16487443.001).
  • [ISSN] 0300-0664
  • [Journal-full-title] Clinical endocrinology
  • [ISO-abbreviation] Clin. Endocrinol. (Oxf)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  •  go-up   go-down


57. Noh SJ, Ahn JY, Lee KS, Kim SH: Pituitary adenoma and concomitant Rathke's cleft cyst. Acta Neurochir (Wien); 2007 Dec;149(12):1223-8
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pituitary adenoma and concomitant Rathke's cleft cyst.
  • Although pituitary adenomas and Rathke's cleft cysts have a shared ancestry, they rarely occur simultaneously.
  • Only 32 reports involving a pituitary adenoma and a concomitant Rathke's cleft cyst were identified upon review of the literature.
  • Next to growth hormone, Prolactin was the most commonly hypersecreted pituitary hormone.
  • Here, we report a patient with a growth hormone- secreting pituitary adenoma associated with a Rathke's cleft cyst.
  • When a non-enhancing cyst-like structure is demonstrated on imaging in a patient with a pituitary adenoma, the possibility of a coexisting Rathke's cleft cyst should be considered.
  • [MeSH-major] Adenoma / surgery. Central Nervous System Cysts / surgery. Growth Hormone-Secreting Pituitary Adenoma / surgery. Neoplasms, Multiple Primary / surgery. Pituitary Neoplasms / surgery
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Image Processing, Computer-Assisted. Magnetic Resonance Imaging. Middle Aged. Neuronavigation. Pituitary Gland / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17914599.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Austria
  • [Number-of-references] 28
  •  go-up   go-down


58. Yang MY, Chen C, Shen CC: Cavernous aneurysm and pituitary adenoma: management of dual intrasellar lesions. J Clin Neurosci; 2005 May;12(4):477-81
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cavernous aneurysm and pituitary adenoma: management of dual intrasellar lesions.
  • A 53-year-old female with a functioning pituitary adenoma was found to also have an unruptured asymptomatic aneurysm in the cavernous sinus portion of the internal carotid artery on MRI.
  • The adenoma had a suprasellar extension with optic chiasm compression and extended into the right cavernous sinus.
  • An aneurysm-like flow-void adjacent to the left internal carotid artery in the sella and embedded in the adenoma was also found.
  • We used a right fronto-pterional approach to clip the aneurysm and to remove the pituitary tumor in a one-stage procedure.
  • [MeSH-major] Adenoma / complications. Arteriovenous Fistula / complications. Pituitary Neoplasms / complications. Sella Turcica / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15925789.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
  •  go-up   go-down


59. Zogheri A, Di Mambro A, Mannelli M, Serio M, Forti G, Peri A: Hyponatremia and pituitary adenoma: think twice about the etiopathogenesis. J Endocrinol Invest; 2006 Sep;29(8):750-3
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hyponatremia and pituitary adenoma: think twice about the etiopathogenesis.
  • Pituitary adenomas may be the cause of the syndrome of inappropriate secretion of antidiuretic hormone (SIADH), although few cases have so far been reported.
  • We described a case of hypotonic hyponatremia in a 76-yr-old man with a pituitary macroadenoma.
  • Thyroid and adrenal function testing did not show any abnormality.
  • Plasma and urinary osmolality (238 and 186 mOsm/kg, respectively) were in agreement with the diagnosis of SIADH.
  • This case very well demonstrates that, in the presence of hyponatremia due to SIADH, more frequently associated co-morbidities (ie mediastinic diseases) have to be searched, even in the presence of a possible, yet rare, cause of this syndrome (ie pituitary adenoma).
  • [MeSH-major] Hyponatremia / etiology. Hyponatremia / radiography. Pituitary Neoplasms / etiology. Pituitary Neoplasms / radiography
  • [MeSH-minor] Aged. Diagnosis, Differential. Humans. Male. Syndrome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17033267.001).
  • [ISSN] 1720-8386
  • [Journal-full-title] Journal of endocrinological investigation
  • [ISO-abbreviation] J. Endocrinol. Invest.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


60. Tunici P, Yu JS: Pituitary adenoma stem cells. Methods Mol Biol; 2009;568:195-201
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pituitary adenoma stem cells.
  • More recently we have isolated tumor stem-like cells also from benign tumors like pituitary adenomas.
  • Cells derived from pituitary adenomas are able to grow as floating aggregates resembling the neurospheres (typical of normal stem cells) in a medium supplemented by growth factors (EGF and bFGF).
  • The immunocytochemical analysis revealed that pituitary tumor stem-like cells are positives for nestin and, when grown for ten days in differentiation medium they express GFAP, BIII tubulin, and S-100.
  • In vitro tumor stem-like cells derived from a patient with a somatotroph adenoma showed high production of growth hormone and prolactin, while cells derived from the same patient but grown in presence of fetal bovine serum showed no production of hormones.
  • [MeSH-major] Cell Culture Techniques / methods. Neoplastic Stem Cells / pathology. Pituitary Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19582428.001).
  • [ISSN] 1064-3745
  • [Journal-full-title] Methods in molecular biology (Clifton, N.J.)
  • [ISO-abbreviation] Methods Mol. Biol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 12629-01-5 / Human Growth Hormone; 9002-62-4 / Prolactin
  •  go-up   go-down


61. Kontogeorgos G: Predictive markers of pituitary adenoma behavior. Neuroendocrinology; 2006;83(3-4):179-88
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Predictive markers of pituitary adenoma behavior.
  • Specific morphologic features may serve as predictive markers of tumor behavior.
  • In the recent World Health Organization classification, the Ki-67 labeling index (LI) represents a major prognostic indicator for pituitary adenomas.
  • Adenomas with more than 3% Ki-67 LI and extensive p53 immunoreactivity are classified as 'atypical adenomas'.
  • A higher apoptotic LI was found in functioning compared with nonfunctioning adenomas, in microadenomas, particularly in corticotrope adenomas, and in untreated adenomas, particularly prolactinomas.
  • Increased chromosome 11 copies are more frequent in functioning, aneuploid pituitary adenomas.
  • Monosomy or partial loss of chromosome 11 in adenomas with a normal or increased DNA LI indicates complex genomic abnormalities of chromosomes, other than chromosome 11.
  • Therefore, morphologic assessment of the somatostatin receptor profile can predict the responsiveness and validate the effectiveness of treatment with somatostatin analogues.
  • [MeSH-major] Adenoma / pathology. Biomarkers, Tumor / metabolism. Pituitary Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17047381.001).
  • [ISSN] 0028-3835
  • [Journal-full-title] Neuroendocrinology
  • [ISO-abbreviation] Neuroendocrinology
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 44
  •  go-up   go-down


62. Yuan Y, You C, Cai B: [Resection of extensive pituitary adenoma via supraorbital keyhole with endoscope-assisted microneurosurgery]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2005 May;19(5):335-7
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Resection of extensive pituitary adenoma via supraorbital keyhole with endoscope-assisted microneurosurgery].
  • OBJECTIVE: To study the methods and techniques of the treatment for extensive suprasellar pituitary adenoma and repairing hole.
  • 2003, 9 patients with extensive suprasellar pituitary adenoma underwent resection via supraorbital keyhole with endoscope-assisted microneurosurgery.
  • Endoscope-assisted microneurosurgery can increase the total-resection and successful rate treatment for extensive suprasellar pituitary adenoma, reduce the possibility of complication, and protect the function of brain from being injured.
  • [MeSH-major] Craniotomy / methods. Neuroendoscopy. Pituitary Neoplasms / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15960431.001).
  • [ISSN] 1002-1892
  • [Journal-full-title] Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
  • [ISO-abbreviation] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  •  go-up   go-down


63. Gokden M, Mrak RE: Pituitary adenoma with craniopharyngioma component. Hum Pathol; 2009 Aug;40(8):1189-93
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pituitary adenoma with craniopharyngioma component.
  • Neoplasms consisting of pituitary adenoma and craniopharyngioma components are rare and are being increasingly recognized.
  • Here, we describe a pituitary adenoma with an intermingled craniopharyngioma component, without forming 2 distinct mass lesions or histologic delineation.
  • It was clinically a nonfunctioning adenoma, which was also negative for pituitary hormones by immunohistochemistry.
  • [MeSH-major] Adenoma / pathology. Craniopharyngioma / pathology. Pituitary Neoplasms / pathology

  • Genetic Alliance. consumer health - Craniopharyngioma.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19427020.001).
  • [ISSN] 1532-8392
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / beta Catenin
  •  go-up   go-down


64. Jia GJ, Wan WQ, Ni M, Jia W, Zhou DB, Zhang BK, Guan SS, Zhang JT: [Preservation of pituitary stalk in the microsurgery of giant pituitary adenoma and its significance]. Zhonghua Yi Xue Za Zhi; 2008 Jun 17;88(23):1627-9
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Preservation of pituitary stalk in the microsurgery of giant pituitary adenoma and its significance].
  • OBJECTIVE: To investigate and elucidate how to preserve the pituitary stalk in the microsurgery of giant pituitary adenoma (GPA) and its clinical significance.
  • METHODS: 45 GPA patients, 23 males and 22 female; aged 40.8, including 12 cases of invasive pituitary adenoma (IPA) underwent craniotomy based on the respective preoperative neuroradiological imaging characteristics.
  • The anatomical relationship between the pituitary stalk and tumor was recorded.
  • The methods to protect the pituitary stalk were summarized.
  • During the surgical proceeding, the pituitary stalk was distinguished from the tumor and preserved well in all 33 cases with non-invasive giant pituitary adenoma.
  • On the contrary, in the 12 cases of invasive giant pituitary adenoma (IPA) the pituitary stalk was visualized in only 7 cases.
  • In the patients with visualized pituitary stalks 4 pituitary stalks were not identified very well.
  • In most cases (91%) the pituitary stalks were located laterally (on the left or right side) or supero-posterior to the tumor, only a few were located anteriorly.
  • CONCLUSION: Pituitary stalk has various anatomical relationships to the entity of GPA; most are located lateral or supero-posterior to the tumor.
  • Identifying and preserving the pituitary stalk well during surgical manipulation will be beneficial to get an excellent outcome.
  • [MeSH-major] Adenoma / surgery. Microsurgery / methods. Pituitary Gland / surgery. Pituitary Neoplasms / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19035104.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  •  go-up   go-down


65. Fontana E, Gaillard R: [Epidemiology of pituitary adenoma: results of the first Swiss study]. Rev Med Suisse; 2009 Oct 28;5(223):2172-4
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Epidemiology of pituitary adenoma: results of the first Swiss study].
  • [Transliterated title] Epidémiologie des adénomes hypophysaires: étude dans une agglomération urbaine de Suisse.
  • Epidemiological data concerning pituitary adenomas are very scarce and in some cases reports are even conflicting.
  • The aim of this study was, therefore, to evaluate in the urban area of Fribourg, the prevalence of relevant clinical pituitary adenoma.
  • General practitioners, endocrinologists and gynaecologists were questioned concerning any patient within this agglomeration presenting with a pituitary micro- or macro-adenoma.
  • Among the 44 adenomas, we observed 13 non secreting macro-adenomas, 16 micro- and 9 macro-prolactinomas, 4 cases of acromegaly and 2 ACTH-dependant Cushing diseases.
  • In the studied area we found a prevalence of 80.5 pituitary adenomas per 100,000, or 1 case per 1241 corroborating a greater prevalence of pituitary adenomas than previously believed.
  • [MeSH-major] Adenoma / epidemiology. Pituitary Neoplasms / epidemiology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19968031.001).
  • [ISSN] 1660-9379
  • [Journal-full-title] Revue médicale suisse
  • [ISO-abbreviation] Rev Med Suisse
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Switzerland
  •  go-up   go-down


66. Vieira JO Jr, Cukiert A, Liberman B: Evaluation of magnetic resonance imaging criteria for cavernous sinus invasion in patients with pituitary adenomas: logistic regression analysis and correlation with surgical findings. Surg Neurol; 2006 Feb;65(2):130-5; discussion 135
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Evaluation of magnetic resonance imaging criteria for cavernous sinus invasion in patients with pituitary adenomas: logistic regression analysis and correlation with surgical findings.
  • BACKGROUND: This study used high-resolution magnetic resonance (MR) imaging (1.5 T) to define and evaluate preoperative imaging criteria for cavernous sinus invasion (CSI) by pituitary adenoma (PA).
  • (1) presence of normal pituitary gland between the adenoma and cavernous sinus (CS), (2) status of the CS venous compartments, (3) CS size, (4) CS lateral wall bulging, (5) displacement of the intracavernous internal carotid artery (ICA) by adenoma, (6) grade of parasellar extension (Knosp-Steiner classification), and (7) percentage of intracavernous ICA encased by the tumor.
  • (1) normal pituitary gland interposed between the adenoma and the CS (PPV, 100.0%), (2) intact medial venous compartment (PPV, 100.0%), and (3) percentage of encasement of the intracavernous ICA lower than 25% (NPV, 100.0%).
  • CONCLUSION: The preoperative diagnosis of CSI by PA is extremely important because endocrinologic remission is rarely obtained after microsurgery alone in patients with invasive tumors.
  • [MeSH-major] Adenoma / pathology. Adenoma / surgery. Cavernous Sinus / pathology. Magnetic Resonance Imaging. Pituitary Neoplasms / pathology. Pituitary Neoplasms / surgery

  • MedlinePlus Health Information. consumer health - MRI Scans.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16427401.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


67. Deniz K, Tanriverdi F, Selçuklu A, Kontaş O, Keleştimur F: Signet ring-like cells in pituitary adenoma. Pathol Res Pract; 2008;204(3):209-12
Hazardous Substances Data Bank. CLOMIPHENE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Signet ring-like cells in pituitary adenoma.
  • We describe a case of non-functioning pituitary adenoma in a 35-year-old woman with a prior history of fertility problems.
  • [MeSH-major] Adenoma / pathology. Pituitary Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18207654.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Chorionic Gonadotropin; 0 / Chromogranins; 0 / Fertility Agents, Female; 0 / Synaptophysin; 1HRS458QU2 / Clomiphene
  •  go-up   go-down


68. Wang H, Li W, Shi D, Ye Z, Qin F, Guo Y, Yuan X: Expression of TGFbeta1 and pituitary adenoma fibrosis. Br J Neurosurg; 2009 Jun;23(3):293-6
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of TGFbeta1 and pituitary adenoma fibrosis.
  • Transsphenoidal approach has been increasingly used in the resection of pituitary adenomas for its minimal invasiveness.
  • In this work, the object is to study the relationship between expression of transforming growth factor beta1 (TGFbeta1) and fibrosis of pituitary adenoma.
  • 38 pituitary adenoma specimens were divided into fibrous group (6 cases) and non-fibrous group (32 cases).
  • Collagen deposition is a significant pathological feature in fibrous pituitary adenomas.
  • TGFbeta1 may play an important role in the fibrosis of adenoma.
  • [MeSH-major] Adenoma. Neoplasm Proteins / metabolism. Peptide Fragments / metabolism. Pituitary Gland / pathology. Pituitary Neoplasms. Transforming Growth Factor beta1 / metabolism

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19533462.001).
  • [ISSN] 1360-046X
  • [Journal-full-title] British journal of neurosurgery
  • [ISO-abbreviation] Br J Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Neoplasm Proteins; 0 / Peptide Fragments; 0 / Transforming Growth Factor beta1; 0 / transforming growth factor beta1 (41-65); 9007-34-5 / Collagen
  •  go-up   go-down


69. Hemminki K, Försti A, Ji J: Incidence and familial risks in pituitary adenoma and associated tumors. Endocr Relat Cancer; 2007 Mar;14(1):103-9
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Incidence and familial risks in pituitary adenoma and associated tumors.
  • We wanted to study incidence trends and familial risks for pituitary adenomas and associated tumors through parental and sibling probands, using the nation-wide Swedish Family-Cancer Database on 10.5 million individuals, containing families with parents and offspring.
  • Cancer data were retrieved from the Swedish Cancer Registry from years 1958 to 2002, including 3239 pituitary tumor patients.
  • The incidence of pituitary adenoma has increased moderately from 1958 to the 1990s and declined thereafter.
  • There were only three offspring-parent pairs with a concordant pituitary tumor, the SIR was not significant.
  • Parental skin cancer (SIR 1.60) and leukemia (1.90, chronic lymphatic leukemia 2.59) were associated with offspring pituitary adenoma diagnosed at any age up to 70 years.
  • There was a strong association of pituitary adenomas with nervous system hemangiopericytomas, SIR 182.
  • The only significant association among siblings was between pituitary tumors and breast cancer (1.46).
  • The risk of pituitary adenoma was marginally increased in individuals whose siblings were diagnosed with colorectal cancer.
  • The results suggest an association of pituitary adenomas with nervous system hemangiopericytomas and breast and colorectal cancers, in addition to some other tumor types.
  • Whether these associations can be explained by the recently identified pituitary adenoma predisposing gene, AIP, remains to be established.
  • [MeSH-major] Adenoma / epidemiology. Genetic Predisposition to Disease. Pituitary Neoplasms / epidemiology

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17395979.001).
  • [ISSN] 1351-0088
  • [Journal-full-title] Endocrine-related cancer
  • [ISO-abbreviation] Endocr. Relat. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  •  go-up   go-down


70. Zhang QH, Liu HS, Yang DZ, Cheng JY: [Image-guided endoscopic transsphenoidal removal of pituitary adenoma]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2005 Jan;40(1):41-4
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Image-guided endoscopic transsphenoidal removal of pituitary adenoma].
  • OBJECTIVE: To assess the role of neuronavigation in assisting endoscopic transsphenoidal surgery for pituitary adenomas.
  • METHODS: Ten endoscopic endonasal transsphenoidal reoperations for pituitary adenomas were selected.
  • Five of 10 patients had gigantic adenoma, 3 microadenoma, 2 large adenoma.
  • Measurements of intraoperative accuracy in the axial, coronal, and.sagittal planes indicated a mean verified system error of 1.5 mm. for pituitary adenomas.
  • [MeSH-major] Hypophysectomy / methods. Pituitary Neoplasms / surgery. Surgery, Computer-Assisted

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15906518.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  •  go-up   go-down


71. Moura FC, Gonçalves AC, Monteiro ML: Seesaw nystagmus caused by giant pituitary adenoma: case report. Arq Neuropsiquiatr; 2006 Mar;64(1):139-41
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Seesaw nystagmus caused by giant pituitary adenoma: case report.
  • Giant pituitary adenomas are uncommonly large tumors, greater than 4 cm in size that can produces endocrine symptoms, visual loss and cranial nerve palsies.
  • We report the rare occurrence of seesaw nystagmus as the presenting sign of giant pituitary adenoma.
  • Perimetry revealed bitemporal hemianopia and magnetic resonance imaging showed a giant pituitary adenoma.
  • [MeSH-major] Adenoma / complications. Hemianopsia / etiology. Nystagmus, Pathologic / etiology. Pituitary Neoplasms / complications

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16622572.001).
  • [ISSN] 0004-282X
  • [Journal-full-title] Arquivos de neuro-psiquiatria
  • [ISO-abbreviation] Arq Neuropsiquiatr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
  •  go-up   go-down


72. Zhang YC, Gao J, Xin T, Zheng ZM, Teng LZ: Expression of survivin in invasive pituitary adenoma. Saudi Med J; 2008 Nov;29(11):1589-92
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of survivin in invasive pituitary adenoma.
  • OBJECTIVE: To investigate the relationship between survivin expression and invasiveness of pituitary adenoma.
  • RESULTS: Survivin was expressed in 46 (69.7%) of the investigated pituitary adenomas.
  • For invasive pituitary adenoma, survivin staining was positive in 35 (89.7%), only 11 (40.7%) specimens were positive in noninvasive tumors.
  • The chi-square test demonstrated a statistically significant difference in survivin expression between invasive and noninvasive pituitary adenoma (chi2=14.309, p=0.0002).
  • CONCLUSION: Survivin was highly associated with invasive pituitary adenoma, it is likely to serve as a useful tool for confirmation of invasive pituitary adenoma and the gene could be an effective target for pituitary adenoma gene therapy.
  • [MeSH-major] Adenoma / metabolism. Microtubule-Associated Proteins / metabolism. Pituitary Neoplasms / metabolism

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18998006.001).
  • [ISSN] 0379-5284
  • [Journal-full-title] Saudi medical journal
  • [ISO-abbreviation] Saudi Med J
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Saudi Arabia
  • [Chemical-registry-number] 0 / BIRC5 protein, human; 0 / Inhibitor of Apoptosis Proteins; 0 / Microtubule-Associated Proteins
  •  go-up   go-down


73. Lonser RR, Kindzelski BA, Mehta GU, Jane JA Jr, Oldfield EH: Acromegaly without imaging evidence of pituitary adenoma. J Clin Endocrinol Metab; 2010 Sep;95(9):4192-6
Faculty of 1000. commentaries/discussion - See the articles recommended by F1000Prime's Faculty of more than 8,000 leading experts in Biology and Medicine. (subscription/membership/fee required).

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Acromegaly without imaging evidence of pituitary adenoma.
  • CONTEXT: GH-secreting pituitary adenomas are nearly always visible on conventional magnetic resonance (MR) imaging.
  • However, management and outcome of acromegalic patients lacking imaging evidence of GH-secreting pituitary adenomas are undefined.
  • OBJECTIVE: The aim was to evaluate surgical exploration for MR-invisible GH-secreting pituitary adenomas.
  • PATIENTS OR OTHER PARTICIPANTS: Consecutive acromegalic patients without imaging evidence of a pituitary adenoma on pre- and postcontrast, spin echo T1-weighted MR imaging and who lacked evidence of an ectopic (nonpituitary) source causing GH excess were included.
  • INTERVENTIONS: Surgical exploration with identification and resection of a pituitary adenoma was performed.
  • RESULTS: Six patients (three males, three females; 3% of all patients) with suspected GH-secreting adenomas did not demonstrate imaging evidence of pituitary adenoma on conventional MR imaging.
  • Three patients underwent a postcontrast, volumetric interpolated breath-hold examination MR-imaging sequence (1.2-mm slice thickness), which revealed a 4-mm pituitary adenoma not seen on the spin echo T1-weighted MR imaging in one patient.
  • A pituitary adenoma was identified and removed in all patients (mean diameter, 5.6 mm; range, 5 to 6.7 mm).
  • Histological analysis confirmed that the lesions were GH-secreting adenomas.
  • CONCLUSION: Acromegaly can be caused by GH-secreting pituitary adenomas that are not evident on conventional MR imaging.
  • Adenomas in some of these patients become evident using volumetric interpolated breath-hold examination MR imaging.
  • Surgical exploration of the pituitary gland in acromegalic patients with endocrine findings consistent with a GH-secreting adenoma but negative MR imaging can lead to identification and removal of an adenoma.

  • Genetic Alliance. consumer health - Acromegaly.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Pituitary. 1999 Jun;2(1):29-41 [11081170.001]
  • [Cites] Pituitary. 2011 Dec;14(4):414-7 [19904612.001]
  • [Cites] J Clin Endocrinol Metab. 2003 Apr;88(4):1565-9 [12679440.001]
  • [Cites] J Clin Endocrinol Metab. 2004 Feb;89(2):667-74 [14764779.001]
  • [Cites] J Clin Endocrinol Metab. 2004 Jul;89(7):3099-102 [15240576.001]
  • [Cites] AJR Am J Roentgenol. 1990 May;154(5):1075-7 [2108545.001]
  • [Cites] AJR Am J Roentgenol. 2005 Jan;184(1):313-9 [15615994.001]
  • [Cites] Eur Radiol. 2005 Mar;15(3):543-8 [15627195.001]
  • [Cites] Eur J Endocrinol. 2005 Mar;152(3):379-87 [15757854.001]
  • [Cites] J Neurosurg. 2006 Jan;104(1):7-19 [16509142.001]
  • [Cites] N Engl J Med. 2006 Dec 14;355(24):2558-73 [17167139.001]
  • [Cites] J Clin Endocrinol Metab. 2008 Jun;93(6):2035-41 [18381584.001]
  • [Cites] Orphanet J Rare Dis. 2008;3:17 [18578866.001]
  • [Cites] Endocr Pract. 2008 Sep;14(6):757-63 [18996799.001]
  • [Cites] J Clin Endocrinol Metab. 2009 May;94(5):1509-17 [19208732.001]
  • [Cites] AJNR Am J Neuroradiol. 2002 Jun-Jul;23(6):995-1002 [12063232.001]
  • (PMID = 20610592.001).
  • [ISSN] 1945-7197
  • [Journal-full-title] The Journal of clinical endocrinology and metabolism
  • [ISO-abbreviation] J. Clin. Endocrinol. Metab.
  • [Language] ENG
  • [Grant] United States / Intramural NIH HHS / /
  • [Publication-type] Case Reports; Journal Article; Multicenter Study; Research Support, N.I.H., Intramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2936064
  •  go-up   go-down


74. Firat AK, Karakas HM, Firat Y, Kahraman B, Erdem G: Spontaneous intracranial hypotension with pituitary adenoma. J Headache Pain; 2006 Feb;7(1):47-50
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spontaneous intracranial hypotension with pituitary adenoma.
  • The characteristic magnetic resonance imaging (MRI) findings are diffuse smooth pachymeningeal thickening and enhancement, downward displacement of posterior fossa structures and pituitary gland enlargement.
  • An unusual case of SIH with pituitary macro-adenoma and subsequent subdural haemorrhage is presented, and its clinical picture, MRI findings and possible pathophysiological mechanism are discussed.
  • [MeSH-major] Adenoma / complications. Intracranial Hypotension / complications. Intracranial Hypotension / pathology. Pituitary Neoplasms / complications. Pituitary Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [ErratumIn] J Headache Pain. 2007 Oct;8(5):317. Firat, Zeynep Y [corrected to Firat, Yezdan]
  • [ErratumIn] J Headache Pain. 2008 Apr;9(2):135
  • (PMID = 16485075.001).
  • [ISSN] 1129-2369
  • [Journal-full-title] The journal of headache and pain
  • [ISO-abbreviation] J Headache Pain
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC3451575
  •  go-up   go-down


75. Lee EJ, Ahn JY, Noh T, Kim SH, Kim TS, Kim SH: Tumor tissue identification in the pseudocapsule of pituitary adenoma: should the pseudocapsule be removed for total resection of pituitary adenoma? Neurosurgery; 2009 Mar;64(3 Suppl):ons62-9; discussion ons69-70
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tumor tissue identification in the pseudocapsule of pituitary adenoma: should the pseudocapsule be removed for total resection of pituitary adenoma?
  • OBJECTIVE: The microsurgical pseudocapsule can be found in the transition zone between an adenoma and the surrounding normal pituitary tissue.
  • Furthermore, we evaluated the remission rate, the changes in pituitary function, and the recurrence rate after intensive resection of the pseudocapsule.
  • METHODS: In 616 patients with pituitary adenomas (Hardy Types I-III) over a period of 14 years, we introduced intensive resection of the microsurgical pseudocapsule to achieve complete tumor removal.
  • A combined pituitary function test and radiological study were performed on the patients before surgery, 1 year after surgery, and at subsequent 1.5-year intervals 2 to 13 years postoperatively.
  • In the 243 patients of the total resection group who underwent combined pituitary function tests more than 2 times after surgery, the surgical remission rate was 99.1% in clinically nonfunctional tumors, 88% in growth hormone-secreting, 70.6% in prolactin-secreting, and 100% in adrenocorticotropic hormone-secreting tumors.
  • There was no statistical difference in improvement or deterioration of pituitary function according to the existence or absence of the pseudocapsule.
  • These results indicate that intensive resection of the pseudocapsule could result in a higher remission rate without deteriorating pituitary function.
  • [MeSH-major] Neurosurgical Procedures / methods. Pituitary Gland / pathology. Pituitary Gland / surgery. Pituitary Neoplasms / pathology. Pituitary Neoplasms / surgery
  • [MeSH-minor] ACTH-Secreting Pituitary Adenoma / surgery. Follow-Up Studies. Growth Hormone-Secreting Pituitary Adenoma / surgery. Humans. Magnetic Resonance Imaging. Microsurgery. Neoplasm Recurrence, Local / epidemiology. Pituitary Function Tests. Postoperative Period. Prolactinoma / surgery. Prospective Studies. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19240574.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


76. Kawamata T, Kubo O, Hori T: Surgical removal of growth hormone-secreting pituitary adenomas with intensive microsurgical pseudocapsule resection results in complete remission of acromegaly. Neurosurg Rev; 2005 Jul;28(3):201-8
MedlinePlus Health Information. consumer health - Brain Aneurysm.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical removal of growth hormone-secreting pituitary adenomas with intensive microsurgical pseudocapsule resection results in complete remission of acromegaly.
  • Although some investigators recommended surgical removal of the borders between pituitary adenoma and the surrounding normal pituitary gland, there is so far little documentation of how intensive dissection of the border zone affects the actual clinical remission rate of pituitary adenomas.
  • We investigated the precise histological characteristics of the boundary, using surgical specimens from patients who underwent intensive resection of "microsurgical pseudocapsule" of growth hormone (GH)-secreting pituitary adenomas.
  • Histologically, most adenomas were in direct contact with normal pituitary gland that formed an increased fibrous component facing the adenoma, without a true histological pseudocapsule.
  • It was impossible to dissect the tumor at exactly the tumor--normal pituitary interface for the whole extent of the pituitary adenoma during surgery, and complete removal of the tumor inevitably included a portion of normal tissue (microsurgical pseudocapsule).
  • The biochemical remission rate was significantly higher in Group 1 than in Group 2 (90.0 vs 61.1%), and Group 1 showed no additional postoperative pituitary hypofunction.
  • The present results suggested that intensive resection of the microsurgical pseudocapsule is essential to accomplish histological and endocrinological total resection of the GH-secreting pituitary adenomas for remission of acromegaly.

  • Genetic Alliance. consumer health - Acromegaly.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15765245.001).
  • [ISSN] 0344-5607
  • [Journal-full-title] Neurosurgical review
  • [ISO-abbreviation] Neurosurg Rev
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


77. Chesnokova V, Zonis S, Ben-Shlomo A, Wawrowsky K, Melmed S: Molecular mechanisms of pituitary adenoma senescence. Front Horm Res; 2010;38:7-14
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Molecular mechanisms of pituitary adenoma senescence.
  • As commonly encountered pituitary adenomas are invariably benign, we examined protective pituitary proliferative mechanisms.
  • In this review we highlight an intrinsic predisposition of pituitary tumors to exhibit senescence-associated molecular pathways and show prospective mechanisms underlying the benign nature of these commonly encountered tumors.
  • [MeSH-major] Adenoma / pathology. Cell Aging. Pituitary Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright (c) 2010 S. Karger AG, Basel.
  • (PMID = 20616490.001).
  • [ISSN] 0301-3073
  • [Journal-full-title] Frontiers of hormone research
  • [ISO-abbreviation] Front Horm Res
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / CDKN1A protein, human; 0 / Cyclin-Dependent Kinase Inhibitor p21; 0 / Neoplasm Proteins; 0 / Securin
  • [Number-of-references] 43
  •  go-up   go-down


78. Heo KW, Park SK: Rhinologic outcomes of concurrent operation for pituitary adenoma and chronic rhinosinusitis: an early experience. Am J Rhinol; 2008 Sep-Oct;22(5):533-6
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rhinologic outcomes of concurrent operation for pituitary adenoma and chronic rhinosinusitis: an early experience.
  • BACKGROUND: The transsphenoidal approach (TSA) is the procedure of choice for the vast majority of pituitary neoplasms.
  • This study was performed to determine if TSA for pituitary tumors could be extended to patients with pituitary adenoma and chronic rhinosinusitis (CRS).
  • METHODS: Medical records, including rhinologic outcomes, were retrospectively assessed in 11 consecutive patients who underwent concurrent TSA and endoscopic sinus surgery (ESS) because of pituitary adenoma and CRS between May 2004 and October 2007.
  • CONCLUSION: Concurrent TSA and ESS can be performed in selected patients with CRS and pituitary adenoma.
  • [MeSH-major] Otorhinolaryngologic Surgical Procedures / methods. Pituitary Neoplasms / surgery. Rhinitis / surgery. Sinusitis / surgery

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • MedlinePlus Health Information. consumer health - Sinusitis.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18954516.001).
  • [ISSN] 1050-6586
  • [Journal-full-title] American journal of rhinology
  • [ISO-abbreviation] Am J Rhinol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


79. Raappana A, Koivukangas J, Pirilä T: 3D modeling-based surgical planning in transsphenoidal pituitary surgery--preliminary results. Acta Otolaryngol; 2008 Sep;128(9):1011-8
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] 3D modeling-based surgical planning in transsphenoidal pituitary surgery--preliminary results.
  • CONCLUSION: The preoperative three-dimensional (3D) modeling of the pituitary adenoma together with pituitary gland, optic nerves, carotid arteries, and the sphenoid sinuses was adopted for routine use in our institution for all pituitary surgery patients.
  • OBJECTIVE: To demonstrate the feasibility of 3D surgical planning for pituitary adenoma surgery using readily available resources.
  • SUBJECTS AND METHODS: The computed tomography (CT) and magnetic resonance imaging (MRI) data of 40 consecutive patients with pituitary adenoma were used to construct 3D models to be used in preoperative planning and during the surgery.
  • [MeSH-major] Adenoma / surgery. Endoscopy / methods. Imaging, Three-Dimensional. Pituitary Neoplasms / surgery. Surgery, Computer-Assisted / methods

  • MedlinePlus Health Information. consumer health - Endoscopy.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19086197.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Controlled Clinical Trial; Journal Article
  • [Publication-country] Norway
  •  go-up   go-down


80. Peker S, Sun I, Kurtkaya-Yapicier O, Elmaci I, Pamir MN: Ectopic pituitary adenoma located at the pituitary stalk. Case report. J Neurosurg Sci; 2005 Mar;49(1):25-9
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ectopic pituitary adenoma located at the pituitary stalk. Case report.
  • Suprasellar located ectopic pituitary adenomas are unusual tumors.
  • The pituitary stalk was preserved.
  • Histopathologic diagnosis was a pituitary adenoma immunoreactive for prolactin.
  • Pituitary hormonal functions returned to normal at 6 months postoperatively.
  • An ectopic adenoma should be suspected in a patient with suprasellar tumor and hyperprolactinemia.
  • Surgical excision of this tumor may result with normal pituitary functions and normal visual acuity.
  • [MeSH-major] Pituitary Gland / pathology. Pituitary Neoplasms / pathology. Prolactinoma / pathology
  • [MeSH-minor] Adult. Craniopharyngioma / pathology. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15990716.001).
  • [ISSN] 0390-5616
  • [Journal-full-title] Journal of neurosurgical sciences
  • [ISO-abbreviation] J Neurosurg Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


81. Mahta A, Haghpanah V, Lashkari A, Heshmat R, Larijani B, Tavangar SM: Non-functioning pituitary adenoma: immunohistochemical analysis of 85 cases. Folia Neuropathol; 2007;45(2):72-7
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Non-functioning pituitary adenoma: immunohistochemical analysis of 85 cases.
  • Pituitary adenomas without clinically active hypersecretion are summarized under the term non-functioning pituitary adenoma (NFPA).
  • Since there are no specific serum markers, the differential diagnosis and treatment imply special difficulties.
  • Eighteen adenomas (21.2%) were immunoreactive to one or two adenohypophysial hormones of which 4 GH positive adenomas had aggressive behaviour (2 significant juxtasellar extensions and 2 recurrences).
  • MIB-1 LI was more than 5% in only 5 cases including 2 invasive adenomas but with no evidence of recurrence.
  • No significant statistical difference between clinical presentations in immunoreactive and non-immunoreactive NFPAs was observed except for unilateral temporal hemianopia which was more common in immunoreactive adenomas (P=0.022).

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17594597.001).
  • [ISSN] 1641-4640
  • [Journal-full-title] Folia neuropathologica
  • [ISO-abbreviation] Folia Neuropathol
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Antibodies, Antinuclear; 0 / Antibodies, Monoclonal; 0 / Ki-67 Antigen; 0 / MIB-1 antibody
  •  go-up   go-down


82. Wolfsberger S, Neubauer A, Bühler K, Wegenkittl R, Czech T, Gentzsch S, Böcher-Schwarz HG, Knosp E: Advanced virtual endoscopy for endoscopic transsphenoidal pituitary surgery. Neurosurgery; 2006 Nov;59(5):1001-9; discussion 1009-10
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Advanced virtual endoscopy for endoscopic transsphenoidal pituitary surgery.
  • This article describes the development of an advanced system of vE for endoscopic transsphenoidal pituitary surgery and its application to teaching, training, and in the routine clinical setting.
  • METHODS: The vE system was applied to a series of 35 patients with pituitary pathology (32 adenomas, three Rathke's cleft cysts) operated endoscopically via the transsphenoidal route at the Department of Neurosurgery of the Medical University Vienna between 2004 and 2006.
  • For planning a safe and tailored opening of the sellar floor, transparent visualization of the pituitary adenoma and the normal gland in relation to the internal carotid arteries was useful.
  • CONCLUSION: According to our experience, vE can be a valuable tool for endoscopic transsphenoidal pituitary surgery for training purposes and preoperative planning.
  • For the experienced pituitary surgeon, vE can depict the individual patient's anatomy, and may, therefore, improve intraoperative orientation.
  • [MeSH-major] Endoscopes. Imaging, Three-Dimensional / instrumentation. Pituitary Neoplasms / pathology. Pituitary Neoplasms / surgery. Surgery, Computer-Assisted / instrumentation. User-Computer Interface

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17143234.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


83. Rocque BG, Herold KA, Salamat MS, Shenker Y, Kuo JS: Symptomatic hyperprolactinemia from an ectopic pituitary adenoma located in the clivus. Endocr Pract; 2009 Mar;15(2):143-8
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Symptomatic hyperprolactinemia from an ectopic pituitary adenoma located in the clivus.
  • OBJECTIVE: To report a case of an ectopic pituitary adenoma in the clivus.
  • METHODS: The clinical, laboratory, and imaging findings of the case are reviewed, and the embryogenesis of the pituitary gland, the pathophysiologic features of this condition, the diagnosis, and the treatment options are discussed.
  • After the resected tissue was examined, the patient was diagnosed as having an ectopic prolactin-producing pituitary adenoma.
  • Surgical resection was undertaken in our patient because of the uncertainty of the diagnosis and the aggressive natural history of more common tumors of the clivus, such as chordomas.
  • Although it is possible that a successful trial of dopaminergic therapy would have obviated surgical intervention, this approach would be associated with additional risks if the diagnosis were incorrect.
  • [MeSH-major] Cranial Fossa, Posterior / pathology. Hyperprolactinemia / diagnosis. Hyperprolactinemia / pathology. Pituitary Neoplasms / diagnosis. Pituitary Neoplasms / pathology

  • Genetic Alliance. consumer health - Galactorrhoea-Hyperprolactinaemia.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19289326.001).
  • [ISSN] 1934-2403
  • [Journal-full-title] Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
  • [ISO-abbreviation] Endocr Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


84. Chen L, Zhuang G, Li W, Liu Y, Zhang J, Tian X: RGD-FasL induces apoptosis of pituitary adenoma cells. Cell Mol Immunol; 2008 Feb;5(1):61-8
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] RGD-FasL induces apoptosis of pituitary adenoma cells.
  • This study was to investigate the cytotoxic effects on pituitary adenoma cell lines GH3/MMQ/AtT20 induced by RGD-FasL and the underlying mechanism.
  • We concluded that RGD-FasL could possibly be considered as a novel therapeutical candidate for the treatment of pituitary adenomas.
  • [MeSH-major] Apoptosis. Fas Ligand Protein / metabolism. Pituitary Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18318996.001).
  • [ISSN] 1672-7681
  • [Journal-full-title] Cellular & molecular immunology
  • [ISO-abbreviation] Cell. Mol. Immunol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, CD95; 0 / Fas Ligand Protein; 0 / Oligopeptides; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / RANK Ligand; 0 / Receptors, Tumor Necrosis Factor, Member 6b; 0 / TNFRSF6B protein, human; 0 / TNFSF11 protein, human; 99896-85-2 / arginyl-glycyl-aspartic acid; EC 2.7.1.24 / Mitogen-Activated Protein Kinase 9; EC 3.4.22.- / Caspases
  • [Other-IDs] NLM/ PMC4072323
  •  go-up   go-down


85. Kılıçlı F, Dökmetaş HS, Gürelik M: Development of pituitary apoplexy during TRH/GnRH test in a patient with pituitary macroadenoma. Singapore Med J; 2010 Nov;51(11):e179-81
Hazardous Substances Data Bank. MENOTROPINS .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Development of pituitary apoplexy during TRH/GnRH test in a patient with pituitary macroadenoma.
  • Pituitary apoplexy occurs as a very rare complication following pituitary function tests.
  • Signs and symptoms are due to the rapid expansion of an infarcted and/or haemorrhagic pituitary adenoma.
  • We report a case of macroadenoma, in which pituitary apoplexy developed 30 minutes after administration of thyrotropin-releasing hormone (TRH) and gonadotropin-releasing hormone (GnRH) injections.
  • MR imaging demonstrated an increase in the size of the pituitary adenoma and several haemorrhagic zones that formed a fluid-fluid level at the centre of the lesion.
  • The pituitary mass was removed using the transsphenoidal approach.
  • Pituitary functions were evaluated by dynamic function tests at six weeks post operation.
  • The patient's pituitary functions and visual acuity were found to be normal.
  • [MeSH-major] Gonadotropin-Releasing Hormone / analysis. Pituitary Apoplexy / etiology. Pituitary Function Tests / adverse effects. Pituitary Neoplasms / pathology. Thyrotropin-Releasing Hormone / analysis

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21140103.001).
  • [ISSN] 0037-5675
  • [Journal-full-title] Singapore medical journal
  • [ISO-abbreviation] Singapore Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
  • [Chemical-registry-number] 33515-09-2 / Gonadotropin-Releasing Hormone; 5Y5F15120W / Thyrotropin-Releasing Hormone; 9002-67-9 / Luteinizing Hormone; 9002-68-0 / Follicle Stimulating Hormone; 9002-71-5 / Thyrotropin
  •  go-up   go-down


86. Kaushik C, Ramakrishnaiah R, Angtuaco EJ: Ectopic pituitary adenoma in persistent craniopharyngeal canal: case report and literature review. J Comput Assist Tomogr; 2010 Jul;34(4):612-4
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ectopic pituitary adenoma in persistent craniopharyngeal canal: case report and literature review.
  • An ectopic location of pituitary adenoma is rare.
  • Nasopharyngeal location of ectopic pituitary adenoma has been attributed to remnants of the Rathke pouch.
  • We describe an interesting case of ectopic pituitary adenoma in the setting of partially persistent craniopharyngeal canal.
  • Embryological basis of ectopic pituitary adenoma and craniopharyngeal canal have been discussed.
  • [MeSH-major] Adenoma / pathology. Adenoma / radiography. Craniopharyngioma / pathology. Craniopharyngioma / radiography. Pituitary Neoplasms / pathology. Pituitary Neoplasms / radiography. Sphenoid Bone / abnormalities
  • [MeSH-minor] Aged. Diagnosis, Differential. Humans. Magnetic Resonance Imaging / methods. Male. Tomography, X-Ray Computed / methods

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20657232.001).
  • [ISSN] 1532-3145
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 8
  •  go-up   go-down


87. Ali R, Noma U, Jansen M, Smyth D: Ectopic pituitary adenoma presenting as midline nasopharyngeal mass. Ir J Med Sci; 2010 Dec;179(4):593-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ectopic pituitary adenoma presenting as midline nasopharyngeal mass.
  • INTRODUCTION: Ectopic pituitary adenomas are extremely rare.
  • We report a case of ectopic pituitary adenoma in the midline of the nasopharynx.
  • This adenoma probably arose from the pharyngeal remnant of Rathke's pouch.
  • An initial diagnosis of Thornwaldt's cyst was made and she underwent upper aerodigestive tract endoscopy and marsupialization of the mass.
  • Histopathological examination revealed ectopic pituitary adenoma.
  • CONCLUSION: Ectopic pituitary adenoma is an important differential diagnosis for a midline nasopharyngeal mass.
  • [MeSH-major] Adenoma / pathology. Craniopharyngioma / pathology. Nasopharyngeal Neoplasms / pathology
  • [MeSH-minor] Female. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Middle Aged. Pituitary Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19129981.001).
  • [ISSN] 1863-4362
  • [Journal-full-title] Irish journal of medical science
  • [ISO-abbreviation] Ir J Med Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ireland
  •  go-up   go-down


88. Jaffe CA: Clinically non-functioning pituitary adenoma. Pituitary; 2006;9(4):317-21
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinically non-functioning pituitary adenoma.
  • Non-functioning pituitary tumors are relatively common.
  • A large number of these tumors are incidentally found pituitary microadenomas (<1 cm) and are usually of no clinical importance.
  • Visual field defects are present in roughly 70% of patients with non-functioning macroadenoma at the time of diagnosis and the majority of these patients have at least growth deficiency and hypogonadism.
  • By immunocytochemistry, the large majority of these tumors are glycoprotein producing and less commonly they are non-functioning somatotroph, lactotroph or corticotoph adenomas.
  • Surgery improves visual defects in the majority of patients and a lesser number will recover pituitary function.
  • In the past, pituitary radiation was commonly administered following pituitary surgery; however the need for routine radiation has recently been reevaluated.
  • Close follow-up with surveillance pituitary scans should be performed after surgery and radiation therapy reserved for patients having significant tumor recurrence.
  • [MeSH-major] Adenoma / diagnosis. Adenoma / therapy. Pituitary Neoplasms / diagnosis. Pituitary Neoplasms / therapy

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17082898.001).
  • [ISSN] 1573-7403
  • [Journal-full-title] Pituitary
  • [ISO-abbreviation] Pituitary
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Hormonal; 0 / Biomarkers
  • [Number-of-references] 17
  •  go-up   go-down


89. Sajko T, Gnjidić I, Talan-Hranilović J: [The importance of the team work in diagnosis of pituitary adenomas: the five-tier World Health Organization classification]. Lijec Vjesn; 2005 May-Jun;127(5-6):134-9
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The importance of the team work in diagnosis of pituitary adenomas: the five-tier World Health Organization classification].
  • [Transliterated title] Vaznost sveukupnog dijagnostickog pristupa u klasifikaciji adenoma hipofize: upute svjetske zdravstvene organizacije.
  • In the last ten years great changes occurred concerning the basic knowledge on pituitary adenomas.
  • Many different classifications of pituitary adenomas were proposed.
  • In 2000 World Health Organization accepted the five-tier classification of pituitary adenomas proposed by Kovacs and Horvath.
  • It is based on clinical and biochemical results, neuroradiological imaging, operative findings, pathohistological examination, immunocytochemistry and electron microscopy studies on more than 10 000 surgically treated pituitary adenomas.
  • Its importance is that it supplies the endocrinologist, neurosurgeon and oncologist with valuable information concerning the biological behavior, growth potential, treatment response and prognosis of pituitary adenomas.
  • Due to the financial restraints, lack of facilities and unavailability of well trained personnel this five-tier classification cannot be fully implemented at our institution.
  • Nonetheless, a perfectly useful diagnosis may be made in instances of limited sources.
  • Together with the novel biological techniques that provide the data on tumor's growth rate, aggressiveness and invasiveness, they ar necessary in establishing the correct diagnosis which will direct patient's future treatment.
  • We strongly advocate in favor of this five-tier classification of pituitary neoplasms and hope it will reach the full implementation.
  • [MeSH-major] Pituitary Neoplasms / classification
  • [MeSH-minor] Adenoma / classification. Adenoma / diagnosis. Humans. World Health Organization

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16281475.001).
  • [ISSN] 0024-3477
  • [Journal-full-title] Lijec̆nic̆ki vjesnik
  • [ISO-abbreviation] Lijec Vjesn
  • [Language] hrv
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Croatia
  •  go-up   go-down


90. Hoellig A, Niehusmann P, Flacke S, Kristof RA: Metastasis to pituitary adenoma: case report and review of the literature. Cent Eur Neurosurg; 2009 Aug;70(3):149-53
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastasis to pituitary adenoma: case report and review of the literature.
  • We present a rare case of a metastasis to a pituitary adenoma and review 14 cases published in the literature to date.
  • Metastases to pituitary adenomas most commonly present with rapidly progressing chiasm compression syndromes, headaches and oculomotor nerve palsies.
  • Metastases to pituitary adenomas have to be considered in the differential diagnosis of sellar tumors.
  • [MeSH-major] ACTH-Secreting Pituitary Adenoma / pathology. ACTH-Secreting Pituitary Adenoma / secondary. Pituitary Neoplasms / pathology. Pituitary Neoplasms / secondary

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Georg Thieme Verlag KG Stuttgart New York.
  • (PMID = 19701874.001).
  • [ISSN] 1868-4912
  • [Journal-full-title] Central European neurosurgery
  • [ISO-abbreviation] Cent Eur Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  •  go-up   go-down


91. Benveniste RJ, King WA, Walsh J, Lee JS, Delman BN, Post KD: Repeated transsphenoidal surgery to treat recurrent or residual pituitary adenoma. J Neurosurg; 2005 Jun;102(6):1004-12
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Repeated transsphenoidal surgery to treat recurrent or residual pituitary adenoma.
  • OBJECT: In this paper the authors describe the indications for and the results and complications of repeated transsphenoidal surgery (RTSS) to treat recurrent or residual pituitary adenoma.
  • METHODS: A retrospective review was conducted of 96 consecutive patients who underwent RTSS to treat recurrent or residual pituitary adenoma.
  • Ninety-six patients underwent RTSS: 42 to treat a recurrent or residual pituitary mass and 54 to treat a recurrent or persistent hormone hypersecretion.
  • [MeSH-major] Adenoma / surgery. Neoplasm Recurrence, Local / surgery. Neoplasm, Residual / surgery. Pituitary Neoplasms / surgery. Sphenoid Bone / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Bromocriptine / therapeutic use. Child. Combined Modality Therapy. Female. Hormone Antagonists / therapeutic use. Humans. Male. Middle Aged. Neurosurgical Procedures. Pituitary ACTH Hypersecretion / mortality. Pituitary ACTH Hypersecretion / surgery. Postoperative Complications / mortality. Postoperative Complications / surgery. Predictive Value of Tests. Radiotherapy. Reoperation. Retrospective Studies. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16028758.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Hormone Antagonists; 3A64E3G5ZO / Bromocriptine
  •  go-up   go-down


92. Hatiboglu MA, Iplikcioglu AC, Ozcan D: Abscess formation within invasive pituitary adenoma. J Clin Neurosci; 2006 Aug;13(7):774-7
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Abscess formation within invasive pituitary adenoma.
  • Pituitary abscess secondary to an adenoma is rare.
  • Magnetic resonance imaging was suggestive of a pituitary abscess with adenoma.
  • Pituitary abscess with adenoma is a serious condition that has a high mortality rate.
  • Therefore, early diagnosis and surgical intervention with antibiotic therapy are necessary.
  • [MeSH-major] Abscess. Pituitary Gland / pathology. Pituitary Neoplasms

  • MedlinePlus Health Information. consumer health - Abscess.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16931019.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
  •  go-up   go-down


93. Cooper O, Geller JL, Melmed S: Ovarian hyperstimulation syndrome caused by an FSH-secreting pituitary adenoma. Nat Clin Pract Endocrinol Metab; 2008 Apr;4(4):234-8
Hazardous Substances Data Bank. MENOTROPINS .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ovarian hyperstimulation syndrome caused by an FSH-secreting pituitary adenoma.
  • Radiological studies included MRI of the pituitary.
  • DIAGNOSIS: Ovarian hyperstimulation syndrome caused by a pituitary adenoma, secreting follicle-stimulating hormone.
  • MANAGEMENT: The patient underwent trans-sphenoidal resection of the adenoma, with subsequent normalization of hormonal values and symptoms.

  • Genetic Alliance. consumer health - Ovarian hyperstimulation syndrome.
  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Mayo Clin Proc. 1996 Jul;71(7):649-56 [8656706.001]
  • [Cites] J Clin Endocrinol Metab. 1996 Jun;81(6):2165-70 [8964846.001]
  • [Cites] Intern Med. 1999 Mar;38(3):266-71 [10337939.001]
  • [Cites] Fertil Steril. 2005 Jan;83(1):208-10 [15652911.001]
  • [Cites] Obstet Gynecol. 2005 May;105(5 Pt 2):1215-8 [15863587.001]
  • [Cites] Gynecol Endocrinol. 2006 Feb;22(2):110-3 [16603438.001]
  • [Cites] Fertil Steril. 2006 Sep;86(3):719.e15-8 [16952513.001]
  • [Cites] Eur J Endocrinol. 2000 Nov;143(5):607-14 [11078984.001]
  • [Cites] Fertil Steril. 2002 Dec;78(6):1311-3 [12477530.001]
  • [Cites] Semin Reprod Med. 2002 Nov;20(4):339-48 [12536357.001]
  • [Cites] J Clin Endocrinol Metab. 2003 May;88(5):1988-93 [12727942.001]
  • [Cites] Endocrinology. 2003 Oct;144(10):4626-36 [12960102.001]
  • [Cites] J Clin Endocrinol Metab. 1984 Dec;59(6):1220-3 [6436289.001]
  • [Cites] Acta Endocrinol (Copenh). 1986 Sep;113(1):29-34 [2945349.001]
  • [Cites] J Clin Endocrinol Metab. 1990 Apr;70(4):859-64 [1690748.001]
  • [Cites] Acta Endocrinol (Copenh). 1990 May;122(5):569-76 [2112813.001]
  • [Cites] J Clin Endocrinol Metab. 1990 Oct;71(4):907-12 [2119391.001]
  • [Cites] J Clin Endocrinol Metab. 1993 Sep;77(3):784-9 [7690365.001]
  • [Cites] Gynecol Oncol. 1995 Mar;56(3):338-44 [7705666.001]
  • [Cites] J Clin Endocrinol Metab. 1998 Oct;83(10):3450-3 [9768644.001]
  • (PMID = 18268519.001).
  • [ISSN] 1745-8374
  • [Journal-full-title] Nature clinical practice. Endocrinology & metabolism
  • [ISO-abbreviation] Nat Clin Pract Endocrinol Metab
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA75979; United States / NIDDK NIH HHS / DK / T32 DK007770; United States / NIDDK NIH HHS / DK / T32 DK007770-06A2; United States / NIDDK NIH HHS / DK / DK007770-06A2; United States / NCI NIH HHS / CA / CA075979-07; United States / NCI NIH HHS / CA / R01 CA075979; United States / NCI NIH HHS / CA / R01 CA075979-07
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 9002-62-4 / Prolactin; 9002-67-9 / Luteinizing Hormone; 9002-68-0 / Follicle Stimulating Hormone
  • [Other-IDs] NLM/ NIHMS117705; NLM/ PMC2777809
  •  go-up   go-down


94. Norberg L, Johansson R, Rasmuson T: Pituitary adenomas in northern Sweden: a study on therapy choices and the risk of second primary tumours. Clin Endocrinol (Oxf); 2008 May;68(5):780-5
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pituitary adenomas in northern Sweden: a study on therapy choices and the risk of second primary tumours.
  • OBJECTIVES: To present the incidence of pituitary adenomas in northern Sweden and to determine whether the incidence of second primary tumours differs from the incidence in the general population or might be related to radiotherapy.
  • PATIENTS: A total of 546 patients with pituitary adenomas were identified in the Cancer Registry of northern Sweden between 1958 and 2004.
  • Only patients with histopathological verification and/or endocrine activity of the adenoma and more than 12 months of follow-up were included, resulting in 376 patients in the study.
  • RESULTS: The total number of person-years at risk for a second primary tumour was 4730.
  • Forty patients had second primary tumours diagnosed more than 12 months after diagnosis of the pituitary adenoma (expected 42.6, SIR 0.94, 95% CI 0.67-1.28).
  • A significantly increased incidence of second primary tumours was seen in 42 men with GH-secreting adenomas.
  • CONCLUSIONS: No significant increase was found in the incidence of second primary tumours in general in patients with pituitary adenomas.
  • An increased incidence of second primary tumours was seen in men with GH-secreting adenomas.
  • [MeSH-major] Adenoma / epidemiology. Growth Hormone-Secreting Pituitary Adenoma / epidemiology. Neoplasms, Second Primary / epidemiology. Pituitary Neoplasms / epidemiology

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17980004.001).
  • [ISSN] 1365-2265
  • [Journal-full-title] Clinical endocrinology
  • [ISO-abbreviation] Clin. Endocrinol. (Oxf)
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  •  go-up   go-down


95. Huang CX, Hou YH, Liu YS: Expression of galectin-3 correlates with apoptosis in pituitary adenoma cells. Neurosci Bull; 2008 Feb;24(1):34-8
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of galectin-3 correlates with apoptosis in pituitary adenoma cells.
  • OBJECTIVE: To investigate the expressions of Galectin-3 (Gal-3), Bcl-2 and Bax in human pituitary adenomas, and to explore the interrelation among them.
  • METHODS: RT-PCR and immunohistochemistry were applied to detect the mRNA and protein expressions of Gal-3, Bcl-2 and Bax in surgically excised human pituitary adenoma tissues, including invasive and non-invasive pituitary adenomas, and the correlation analysis was performed.
  • RESULTS: The Gal-3 and Bcl-2 expressions in the invasive pituitary group were significantly higher than those in the non-invasive group, and the expression of Bax had no significant difference between the two groups.
  • CONCLUSION: Gal-3 may function through a cell death inhibition pathway involving Bcl-2 to enhance cell proliferation, which result in the invasive growth of pituitary adenoma.
  • These results indicate that Gal-3 has an important role in pituitary tumor cell proliferation and may serves as a possible therapeutic target in treatment of pituitary tumors.
  • [MeSH-major] Adenoma / metabolism. Apoptosis. Galectin 3 / metabolism. Pituitary Neoplasms / metabolism

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18273074.001).
  • [ISSN] 1995-8218
  • [Journal-full-title] Neuroscience bulletin
  • [ISO-abbreviation] Neurosci Bull
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Singapore
  • [Chemical-registry-number] 0 / BAX protein, human; 0 / Galectin 3; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / RNA, Messenger; 0 / bcl-2-Associated X Protein
  •  go-up   go-down


96. Liu H, Zhang Q, Yang Z, Sun Y: [The endoscopic extended transsphenoidal surgery for gigantic pituitary adenoma]. Lin Chuang Er Bi Yan Hou Ke Za Zhi; 2005 Jan;19(2):57-9
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The endoscopic extended transsphenoidal surgery for gigantic pituitary adenoma].
  • OBJECTIVE: The purpose of the study is to evaluate the ability of endoscopic extended transsphenoidalapproach for treatment of gigantic pituitary adenoma.
  • METHOD: The clinical data of 13 cases with gigantic pituitary adenoma treated by endoscopic extended transsphenoidalapproach was studied retrospectively.
  • CONCLUSION: The extended transsphenoidalapproach can be used for treatment of gigantic pituitary tumor.
  • [MeSH-major] Adenoma / surgery. Endoscopy. Hypophysectomy / methods. Pituitary Neoplasms / surgery

  • MedlinePlus Health Information. consumer health - Endoscopy.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15844575.001).
  • [Journal-full-title] Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology
  • [ISO-abbreviation] Lin Chuang Er Bi Yan Hou Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  •  go-up   go-down


97. Nielsen EH, Lindholm J, Laurberg P, Bjerre P, Christiansen JS, Hagen C, Juul S, Jørgensen J, Kruse A, Stochholm K: Nonfunctioning pituitary adenoma: incidence, causes of death and quality of life in relation to pituitary function. Pituitary; 2007;10(1):67-73
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nonfunctioning pituitary adenoma: incidence, causes of death and quality of life in relation to pituitary function.
  • The incidence of clinically significant, nonfunctioning pituitary adenoma, requiring surgical treatment, has not been established.
  • According to previous studies, both surgery type and subsequent radiotherapy may have an impact on quality of life (QOL), and some studies have shown increased cardiovascular mortality in patients with pituitary disease.
  • We studied all patients with functionless, suprasellar pituitary adenoma who were operated on during the period 1985-1996 (N = 192; transsphenoidal surgery = 160, craniotomy = 32).
  • Postoperatively, 27% of the patients had normal pituitary function and 27% were panhypopituitary.
  • Death from cardiovascular, cerebrovascular and malignant diseases was not increased.
  • [MeSH-major] Adenoma / mortality. Pituitary Neoplasms / mortality

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17356906.001).
  • [ISSN] 1386-341X
  • [Journal-full-title] Pituitary
  • [ISO-abbreviation] Pituitary
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


98. Platta CS, Mackay C, Welsh JS: Pituitary adenoma: a radiotherapeutic perspective. Am J Clin Oncol; 2010 Aug;33(4):408-19
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pituitary adenoma: a radiotherapeutic perspective.
  • Pituitary adenomas comprise approximately 10% to 20% of all central nervous system neoplasms whereas autopsy series have suggested that the incidence of pituitary adenoma in the general population may approach 25%.
  • Several treatment modalities are used in the treatment of pituitary adenomas, including observation, surgery, medical intervention, and radiotherapy.
  • The treatment modality employed depends greatly on the type of pituitary adenoma and presenting symptoms.
  • This review will discuss the biology of pituitary adenomas and the current management principles for the treatment of prolactinomas, Cushing disease, acromegaly, and nonsecretory adenomas, with an emphasis on the published radiotherapeutic literature.
  • [MeSH-major] Adenoma / radiotherapy. Pituitary Neoplasms / radiotherapy
  • [MeSH-minor] Adult. Follow-Up Studies. Humans. Hypothalamus / physiology. Incidence. Organ Size. Pituitary Gland / anatomy & histology. Pituitary Gland / physiology. Retrospective Studies. United States / epidemiology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19687730.001).
  • [ISSN] 1537-453X
  • [Journal-full-title] American journal of clinical oncology
  • [ISO-abbreviation] Am. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 155
  •  go-up   go-down


99. Liu ZX, Yuan XR, Fang JS, Huang J, Li YB, Luo C, Yang ZQ, Liu YS: [Mononostril-septum-transsphenoidal approach for pituitary adenoma]. Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2006 Apr;31(2):281-3
MedlinePlus Health Information. consumer health - Pituitary Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Mononostril-septum-transsphenoidal approach for pituitary adenoma].
  • OBJECTIVE: To summarize the mononostril-septum-transsphenoidal approach for pituitary adenoma.
  • METHODS: The clinical features, operative techniques, and outcome of 36 patients with pituitary adenoma were analyzed retrospectively.
  • [MeSH-major] Adenoma / surgery. Nasal Septum / surgery. Pituitary Neoplasms / surgery. Sphenoid Sinus / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16706134.001).
  • [ISSN] 1672-7347
  • [Journal-full-title] Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
  • [ISO-abbreviation] Zhong Nan Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  •  go-up   go-down


100. Zhou PZ, Cheng SW, Yang ZC, Ma WC, Dong W, Peng LL, Jiang S: [Repair and reconstruction of diaphragmatic defect during transcranial pituitary adenoma surgery]. Sichuan Da Xue Xue Bao Yi Xue Ban; 2010 Jul;41(4):728-30
MedlinePlus Health Information. consumer health - Plastic and Cosmetic Surgery.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Repair and reconstruction of diaphragmatic defect during transcranial pituitary adenoma surgery].
  • OBJECTIVE: To investigate the application value of titanium-clip and artificial menigeal in the sella diaphragm repair and reconstruction during transcranial pituitary adenoma surgery.
  • METHODS: Thirty eight patients undergoing transcranial pituitary adenoma surgery received sella diaphragmatic defect repair and reconstruction after the removal of tumor, intraoperative diaphragmatic defect was classified as three grades, titanium-clip, artificial menigeal and EC glue were used for the sella diaphragmatic repair and reconstruction.
  • There was no significant difference in pituitary function and vision improvement between the two groups as the occurrence of diabetes insipidus (P > 0.05).
  • CONCLUSION: It is important to repair the sellae diaphragm defect during transcranial pituitary adenoma surgery, which could reduce short-term and long-term complication.
  • [MeSH-major] Adenoma / surgery. Pituitary Neoplasms / surgery. Prosthesis Implantation / methods. Reconstructive Surgical Procedures / methods. Sella Turcica / surgery

  • MedlinePlus Health Information. consumer health - Pituitary Tumors.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20848801.001).
  • [ISSN] 1672-173X
  • [Journal-full-title] Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
  • [ISO-abbreviation] Sichuan Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  •  go-up   go-down






Advertisement