[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 100 of about 1099
1. Imelda F, Bandar IN, Setiyohadi B, Suwondo P, Nasar IM, Darwito: Postural shortening due to primary hyperparathyroidism caused by parathyroid adenoma. Acta Med Indones; 2006 Apr-Jun;38(2):89-91
Genetic Alliance. consumer health - Hyperparathyroidism, primary.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Postural shortening due to primary hyperparathyroidism caused by parathyroid adenoma.
  • Osteoporosis can be primary or secondary.
  • Secondary osteoporosis is the result of an underlying disease such as an endocrine abnormality, and an example of such is primary hyperparathyroidism.
  • The most common cause of primary hyperparathyroidism is parathyroid gland adenoma.
  • The diagnosis of primary hyperparathyroidism is based on the following biochemical examinations: parathyroid hormone, serum calcium, creatinine clearance, 24 hour urinary calcium, and another examination such as parathyroid gland scan.
  • The patient was diagnosed with primary hyperparathyroidism caused by parathyroid gland adenoma.
  • We found high levels of parathyroid hormone and low levels of serum calcium caused by secondary hyperparathyroidism.
  • [MeSH-major] Adenoma / diagnosis. Body Height / physiology. Hyperparathyroidism, Primary / physiopathology. Parathyroid Neoplasms / diagnosis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16799210.001).
  • [ISSN] 0125-9326
  • [Journal-full-title] Acta medica Indonesiana
  • [ISO-abbreviation] Acta Med Indones
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Indonesia
  •  go-up   go-down


2. Oliveira MA, Maeda SS, Dreyer P, Lobo A, Andrade VP, Hoff AO, Biscolla RP, Smanio P, Brandão CM, Vieira JG: [Importance of parathyroid SPECT and 99mTc scintigraphy, and of clinical, laboratorial, ultrasonographic and citologic correlation in the pre-operative localization of the parathyroid adenoma - pictorial assay]. Arq Bras Endocrinol Metabol; 2010 Jun;54(4):352-61

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Importance of parathyroid SPECT and 99mTc scintigraphy, and of clinical, laboratorial, ultrasonographic and citologic correlation in the pre-operative localization of the parathyroid adenoma - pictorial assay].
  • [Transliterated title] Importância da complementação com SPECT e 99mTc na cintilografia das paratiroides e da correlação clínica, laboratorial, ultrassonográfica e citológica na localização pré-operatória do adenoma de paratiroide - ensaio pictórico.
  • OBJECTIVE: In patients with primary hyperparathyroidism, candidates for surgical intervention, the parathyroid pre-operative localization is of fundamental importance in planning the appropriate surgical approach.
  • MATERIALS AND METHODS: The additional acquisition of SPECT and Technetium-99m images, during parathyroid scintigraphy with Sestamibi, is not common practice.
  • RESULTS: In our experience, the complete protocol in parathyroid scintigraphy increases the accuracy of pre-operative parathyroid localization.
  • CONCLUSION: The complete utilization of all available nuclear medicine methods (SPECT e 99mTc) and image interpretation in a multidisciplinary context can improve the accuracy of parathyroid scintigraphy.
  • [MeSH-major] Adenoma / pathology. Adenoma / radionuclide imaging. Parathyroid Neoplasms / pathology. Parathyroid Neoplasms / radionuclide imaging. Radiopharmaceuticals. Technetium Tc 99m Sestamibi. Tomography, Emission-Computed, Single-Photon / standards

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Arq Bras Endocrinol Metabol. 2010 Jun;54(4):343-4 [20625644.001]
  • (PMID = 20625646.001).
  • [ISSN] 1677-9487
  • [Journal-full-title] Arquivos brasileiros de endocrinologia e metabologia
  • [ISO-abbreviation] Arq Bras Endocrinol Metabol
  • [Language] por
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Brazil
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


3. Zhu X, Zhai H, Tang SF, Cheng Y: Intrathyroidal parathyroid adenoma presenting with neuromuscular manifestation. Neurol India; 2009 May-Jun;57(3):340-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intrathyroidal parathyroid adenoma presenting with neuromuscular manifestation.
  • Primary hyperparathyroidism (PHPT) is not an uncommon endocrine disorder.
  • Serum calcium, alkaline phosphatase, and parathyroid hormone were elevated and serum phosphorus was low.
  • The right lobectomy examination confirmed the diagnosis of an intrathyroidal parathyroid adenoma of the right gland.
  • [MeSH-major] Hyperparathyroidism / etiology. Neuromuscular Junction Diseases / etiology. Parathyroid Neoplasms / complications

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19587481.001).
  • [ISSN] 0028-3886
  • [Journal-full-title] Neurology India
  • [ISO-abbreviation] Neurol India
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


Advertisement
4. Szende B, Arvai K, Peták I, Nagy K, Végsô G, Perner F: [Changes in gene expression in the course of proliferative processes in the parathyroid gland]. Magy Onkol; 2006;50(2):137-40
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Changes in gene expression in the course of proliferative processes in the parathyroid gland].
  • The aim of this study was to investigate the changes in expression pattern of the most important genes connected with apoptosis in proliferative apoptotic lesions (hyperplasia, adenoma), applying cDNA microarray technique, in order to promote the possible diagnostic or therapeutic utilisation of any difference in gene expression compared to the healthy (normal) parathyroid gland.
  • Samples were taken from surgically removed 2 hyperplasias, 2 adenomas and 2 normal parathyroid glands.
  • The samples deriving from hyperplasia or adenoma were compared to samples from normal parathyroid glands.
  • The following genes were overexpressed in both hyperplasia and adenoma: CHEK1, ATM, BCL-XL, FAS, TNF, cIAP1, TRAIL, FADD, CASP 4,5,6,8, CD120b, CD137, LTA, TANK, TARF2, CAD, LIGHTR, DR3LG.
  • CASP1,10, BFAR, BOD, BCL2L2, TRANCE were underexpressed in both hyperplasia and adenoma.
  • Overexpressed only in adenoma: APOLLON, RIPK1, LTB, LTBR, CASP2,13, cIAP2, CIDEB.
  • Underexpressed only in adenoma: TRAF4 and FASLG.
  • As a result of this study, both pro-apoptotic and antiapoptotic genes were identified in hyperplasia and adenoma of the parathyroid gland.
  • [MeSH-major] Adenoma / genetics. Apoptosis / genetics. Gene Expression. Gene Expression Regulation, Neoplastic. Parathyroid Glands / metabolism. Parathyroid Neoplasms / genetics


5. Chang MC, Tsai SC, Lin WY: Dual-phase 99mTc-MIBI parathyroid imaging reveals synchronous parathyroid adenoma and papillary thyroid carcinoma: a case report. Kaohsiung J Med Sci; 2008 Oct;24(10):542-7
MedlinePlus Health Information. consumer health - Thyroid Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dual-phase 99mTc-MIBI parathyroid imaging reveals synchronous parathyroid adenoma and papillary thyroid carcinoma: a case report.
  • The possibility of a coincidental appearance of hyperparathyroidism and thyroid cancer is not often considered because of its low incidence.
  • Here, we present a case of a 49-year-old woman with a parathyroid adenoma coexisting with two sites of papillary thyroid carcinoma.
  • Dual-phase 99mTc-methoxyisobutylisonitrile (MIBI) parathyroid imaging before the operation correctly visualized the site of the parathyroid adenoma.
  • Total thyroidectomy and parathyroidectomy of a solitary parathyroid adenoma were performed.
  • This case illustrates the need for clinical awareness of concomitant hyperparathyroidism and thyroid cancer.
  • Dual-phase 99mTc- MIBI parathyroid imaging may be useful for detecting indolent thyroid cancer before it becomes a distinct disease.
  • [MeSH-major] Carcinoma, Papillary / diagnosis. Neoplasms, Multiple Primary / diagnosis. Parathyroid Neoplasms / diagnosis. Technetium Tc 99m Sestamibi. Thyroid Neoplasms / diagnosis
  • [MeSH-minor] Female. Humans. Hyperparathyroidism / diagnosis. Middle Aged

  • Genetic Alliance. consumer health - Parathyroid carcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19181586.001).
  • [ISSN] 1607-551X
  • [Journal-full-title] The Kaohsiung journal of medical sciences
  • [ISO-abbreviation] Kaohsiung J. Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
  • [Chemical-registry-number] 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


6. Sakuma T, Nishimura K, Deturmeny J, Kawano K: [Functioning oxyphil cell adenoma of parathyroid diagnosed with ureteral stone]. Prog Urol; 2009 Oct;19(9):636-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Functioning oxyphil cell adenoma of parathyroid diagnosed with ureteral stone].
  • A case of oxyphil cell adenoma of parathyroid is presented.
  • Left hydronephrosis, elevated serum calcium-parathyroid hormone and a nodule in the right neck suggested functioning parathyroid adenoma.
  • Resected adenoma (15 mm x 10 mm x 5 mm) was exclusively composed of oxyphil cell.
  • Production of parathyroid hormone by oxyphil cells was confirmed by immunohistochemistry.
  • This case was found to be the smallest parathyroid oxyphil cell adenoma hitherto reported that caused urolithiasis.
  • [MeSH-major] Adenoma, Oxyphilic / complications. Adenoma, Oxyphilic / diagnosis. Parathyroid Neoplasms / complications. Parathyroid Neoplasms / diagnosis. Ureteral Calculi / complications

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19800555.001).
  • [ISSN] 1166-7087
  • [Journal-full-title] Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie
  • [ISO-abbreviation] Prog. Urol.
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  •  go-up   go-down


7. Prasad KK, Agarwal G, Mishra SK, Krishnani N: Oxyphilic cell adenoma of parathyroid resulting in primary hyperparathyroidism and osteitis fibrosa cystica--a case report. Indian J Pathol Microbiol; 2006 Jul;49(3):448-50
Genetic Alliance. consumer health - Hyperparathyroidism, primary.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Oxyphilic cell adenoma of parathyroid resulting in primary hyperparathyroidism and osteitis fibrosa cystica--a case report.
  • Adenomas of the parathyroid gland, the majority of which are of the solitary chief cell type, are the most frequent cause of primary hyperparathyroidism (pHPT).
  • Parathyroid adenomas composed predominantly or exclusively of oxyphil cells are rare and most oxyphil cell adenomas of this organ remain clinically silent.
  • We present here a case of hyperfunctioning oxyphil cell adenoma of the parathyroid gland resulting in pHPT, osteitis fibrosa cystica and simultaneous bilateral fractures upper shafts of femora.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Hyperparathyroidism, Primary / etiology. Osteitis Fibrosa Cystica / etiology. Parathyroid Glands / pathology. Parathyroid Neoplasms / complications. Parathyroid Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17001919.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  •  go-up   go-down


8. Knezević-Obad A, Tomić-Brzac H, Zarković K, Dodig D, Stromar IK: Diagnostic pitfalls in parathyroid gland cytology. Coll Antropol; 2010 Mar;34(1):25-9
Hazardous Substances Data Bank. METHYLENE BLUE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diagnostic pitfalls in parathyroid gland cytology.
  • The aim of this study is to establish possibilities of using cytology in the diagnosis of parathyroid gland adenoma.
  • 475 patients, all suspected to have parathyroid gland disease, were examined over a three-year period (from 1 of January 2006 to 31 of December 2008) in the Clinical Department of Nuclear Medicine and Radiation Protection, University Hospital Center Zagreb, Croatia.
  • The parathyroid hormone (PTH) analysis was made for all punctates.
  • The adenoma was diagnosed via morphological characteristics in 71 out of 288 punctates that were proven adequate for cytological analysis.
  • Increased PTH levels were later on established in all diagnosed adenomas.
  • All patients with cytology-based diagnosis of parathyroid gland adenoma were sent to surgery, and the cytological diagnosis was confirmed by pathohistology.
  • In three cases, the parathyroid gland adenoma was established by pathohistology, although in these cases the cytological diagnosis was negative.
  • The cytological diagnosis of parathyroid gland adenoma can be considered reliable in 96% of cases, provided that the echosonographic structure and localisation of the punctured node is noted, and assuming that material adequate for cytological analysis is obtained by FNAB.
  • Possible pitfalls are oncocytic types of parathyroid adenoma, intranuclear inclusions and papillary formation of epithelial cells, and cystic degeneration of nodules.
  • [MeSH-major] Adenoma / pathology. Biopsy, Fine-Needle / standards. Parathyroid Glands / pathology. Parathyroid Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Cell Nucleus / pathology. Eosine Yellowish-(YS). Epithelial Cells / pathology. False Negative Reactions. Female. Humans. Inclusion Bodies / pathology. Male. Methylene Blue. Middle Aged. Parathyroid Hormone / blood. Reproducibility of Results. Young Adult

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20432729.001).
  • [ISSN] 0350-6134
  • [Journal-full-title] Collegium antropologicum
  • [ISO-abbreviation] Coll Antropol
  • [Language] eng
  • [Publication-type] Journal Article; Validation Studies
  • [Publication-country] Croatia
  • [Chemical-registry-number] 0 / May-Grunwald Giemsa; 0 / Parathyroid Hormone; T42P99266K / Methylene Blue; TDQ283MPCW / Eosine Yellowish-(YS)
  •  go-up   go-down


9. Abboud B, Sleilaty G, Ayoub S, Hachem K, Smayra T, Ghorra C, Abadjian G: Intrathyroid parathyroid adenoma in primary hyperparathyroidism: can it be predicted preoperatively? World J Surg; 2007 Apr;31(4):817-23
Genetic Alliance. consumer health - Hyperparathyroidism, primary.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intrathyroid parathyroid adenoma in primary hyperparathyroidism: can it be predicted preoperatively?
  • INTRODUCTION: The role of cervical ultrasonography (US)-guided surgery for intrathyroid parathyroid adenoma in primary hyperparathyroidism is rarely reported.
  • METHODS: From 1996 to 2003, cervical explorations were performed in 178 patients (mean age 57 years) with primary hyperparathyroidism.
  • Patients' characteristics were reviewed to identify predictive factors for intrathyroid adenoma.
  • RESULTS: Cervical US identified abnormal parathyroid glands in 163 of 178 patients, with a positive predictive value (PPV) of 100%.
  • Six patients (3.4%) were found to have intrathyroid parathyroid adenomas (two in the superior parathyroid and four in the inferior parathyroid).
  • Cervical US predicted this anomaly in four of six patients (67%) in whom the thyroid gland was not nodular and allowed total enucleation of the adenoma to be performed in three and subtotal thyroid loboisthmectomy in three; these operations were performed uneventfully and rapidly.
  • On multivariable analysis, no factor predicted intrathyroid localization of parathyroid adenoma.
  • CONCLUSIONS: The PPV of high-resolution cervical US for identifying an abnormal parathyroid gland was 100% in this series.
  • It was 80% for predicting intrathyroid localization of the adenoma.
  • This method allows us to shorten the operating time by guiding the exploration immediately toward the thyroid gland.
  • [MeSH-major] Hyperparathyroidism, Primary / etiology. Parathyroid Neoplasms / surgery. Parathyroid Neoplasms / ultrasonography

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17354026.001).
  • [ISSN] 0364-2313
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


10. Kucera T, Veselý D, Pácová H, Martínek J, Astl J: Expression of nitric oxide synthases in parathyroid gland adenoma and parathyroid gland hyperplasia. Neuro Endocrinol Lett; 2005 Aug;26(4):373-6
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of nitric oxide synthases in parathyroid gland adenoma and parathyroid gland hyperplasia.
  • OBJECTIVE: The aim of the presented study was to perform the immunohistochemical detection of endothelial (eNOS) and inducible (iNOS) isoform of nitric oxide synthase in the adenomatous and hyperplastic parathyroid gland in relation to the apoptotic process.
  • DESIGN AND SETTING: Tissue samples from 12 patients with parathyroid gland adenoma (PGA) and 10 patients with secondary parathyroid gland hyperplasia (PGH) were collected during surgery at the Department of Otorhinolaryngology and Head and Neck Surgery of The First Faculty of Medicine in Prague.
  • RESULTS: The immunoreactivity to eNOS antibody was observed in the endothelial lining of vessels in PGA, PGH and in the rim of normal parathyroid gland adjacent to PGA sample.
  • CONCLUSION: eNOS observed in the vasculature of the enlarged parathyroid glands can serve as a factor that contributes to the viability of hypertrophic pathologic tissue.
  • [MeSH-major] Adenoma / metabolism. Nitric Oxide Synthase Type II / metabolism. Nitric Oxide Synthase Type III / metabolism. Parathyroid Glands / enzymology. Parathyroid Neoplasms / metabolism

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16136006.001).
  • [ISSN] 0172-780X
  • [Journal-full-title] Neuro endocrinology letters
  • [ISO-abbreviation] Neuro Endocrinol. Lett.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Sweden
  • [Chemical-registry-number] EC 1.14.13.39 / NOS3 protein, human; EC 1.14.13.39 / Nitric Oxide Synthase Type II; EC 1.14.13.39 / Nitric Oxide Synthase Type III
  •  go-up   go-down


11. Târcoveanu E, Niculescu D, Cotea E, Moldovanu R, Vasilescu A, Crumpei F, Zbranca E, Zugun F, Rusu V, Ferariu D: [Parathyroid glands involvement in multiple endocrine neoplasia]. Rev Med Chir Soc Med Nat Iasi; 2009 Apr-Jun;113(2):482-96
MedlinePlus Health Information. consumer health - Pancreatic Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Parathyroid glands involvement in multiple endocrine neoplasia].
  • Parathyroid gland involvement is usually noted in Multiple Endocrine Neoplasia (MEN) type I and type II.
  • Parathyroid glands tumor associated with endocrine pancreatic tumor, as well as pituitary tumors is the typical pattern of MEN I.
  • The parathyroid gland is the most frequent abnormality in MEN I.
  • CASES REPORTS: We presented five cases with MEN I and parathyroid glands involvement.
  • In three cases with young ages (28-33 years old) and familial setting, the MEN I syndrome was "complete" (parathyroid adenoma, gastrinoma or insulinoma and pituitary adenoma--prolactinoma or GH-secreting tumors), and, in the other two cases, with 57 and 68 years old respectively, the MEN I syndrome was "incomplete" with parathyroid glands and pituitary gland involvement.
  • Unfortunately one patients died due to severe endocrine disorder.
  • During the necropsy, the pituitary adenoma has been diagnosed.
  • The imagistic and laboratory test diagnosed a tumor situated into the pancreatic body, and an parathyroid adenoma.
  • The resection of pancreatic tumor associated with resection of the parathyroid adenoma, in the same time, were performed.
  • The other two cases with "incomplete" MEN were older then the first patients, and were diagnosed with hyperparathyrodism and pituitary gland tumor.
  • The resection of parathyroid gland adenoma has been performed in both cases, with uneventful postoperative course.
  • CONCLUSIONS: The parathyroid glands involvement in MEN is common.
  • There are two kinds of MEN associated with parathyroid gland involvement: the "complete" form, especially in young patients, with diffuse involvement of the parathyroid glands, and the subtotal parathyroidy is the best choice, and the "incomplete" form, especially in elderly, with the involvement of a single parathyroid gland; in this way, the resection of the adenoma associated with biopsy from the other parathyroid gland is the best approach.
  • [MeSH-major] Adenoma / surgery. Gastrinoma / surgery. Insulinoma / surgery. Multiple Endocrine Neoplasia Type 1 / surgery. Pancreatectomy. Pancreatic Neoplasms / surgery. Parathyroid Neoplasms / surgery. Parathyroidectomy
  • [MeSH-minor] Adult. Aged. Fatal Outcome. Female. Humans. Hyperparathyroidism, Secondary / diagnosis. Hyperparathyroidism, Secondary / etiology. Male. Middle Aged. Multiple Endocrine Neoplasia / surgery. Pituitary Neoplasms / diagnosis. Pituitary Neoplasms / surgery. Prolactinoma / diagnosis. Prolactinoma / surgery. Treatment Outcome

  • Genetic Alliance. consumer health - Multiple Endocrine Neoplasia.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21495355.001).
  • [ISSN] 0048-7848
  • [Journal-full-title] Revista medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti din Iaş̧i
  • [ISO-abbreviation] Rev Med Chir Soc Med Nat Iasi
  • [Language] rum
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Romania
  •  go-up   go-down


12. Cappelli C, Pelizzari G, Pirola I, Gandossi E, De Martino E, Delbarba A, Agosti B, Agabiti Rosei E, Castellano M: Modified percutaneous ethanol injection of parathyroid adenoma in primary hyperparathyroidism. QJM; 2008 Aug;101(8):657-62
Hazardous Substances Data Bank. ETHANOL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Modified percutaneous ethanol injection of parathyroid adenoma in primary hyperparathyroidism.
  • Surgery is the treatment of choice for symptomatic primary hyperparathyroidism; unlikely few patients do not meet established surgical criteria or have comorbid conditions that prohibit surgery.
  • It is currently in use for the treatment of secondary or tertiary hyperparathyroidism, however, few studies or case reports suggest it for the treatment of primary hyperparathyroidism.
  • [MeSH-major] Adenoma / therapy. Ethanol / administration & dosage. Hyperparathyroidism, Primary / therapy. Parathyroid Neoplasms / therapy. Solvents / administration & dosage

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18499732.001).
  • [ISSN] 1460-2393
  • [Journal-full-title] QJM : monthly journal of the Association of Physicians
  • [ISO-abbreviation] QJM
  • [Language] eng
  • [Publication-type] Case Reports; Evaluation Studies; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Solvents; 3K9958V90M / Ethanol
  •  go-up   go-down


13. Calbo L, Campennì A, Calbo E, Catalfamo A, Sciglitano P, Niceta M, Borzì R, Lizio R, Gorgone S: [Hyperparathyroidism from mediastinal parathyroid adenoma. Case report]. G Chir; 2008 Jun-Jul;29(6-7):295-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Hyperparathyroidism from mediastinal parathyroid adenoma. Case report].
  • [Transliterated title] Iperparatiroidismo da adenoma paratiroideo a localizzazione mediastinica. Caso clinico.
  • The authors, after reviewing parathyroid gland diseases, their location, and the modern strategies that can be used for their pre-operative detection, describe a case of primary hyperparathyroidism which recently came to their attention.
  • The use of a combination of instrumental techniques (US, scintigraphy and SPEcT) enabled them to establish, prior to surgery, the mediastinal ectopic site of the parathyroid adenoma.
  • [MeSH-major] Adenoma / complications. Choristoma / complications. Hyperparathyroidism, Primary / etiology. Mediastinal Neoplasms / complications. Parathyroid Neoplasms / complications
  • [MeSH-minor] Adult. Female. Humans. Parathyroid Glands / radionuclide imaging. Parathyroidectomy. Tomography, Emission-Computed, Single-Photon. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18544269.001).
  • [ISSN] 0391-9005
  • [Journal-full-title] Il Giornale di chirurgia
  • [ISO-abbreviation] G Chir
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


14. Schachter PP, Ayesh S, Matouk I, Schneider T, Czerniak A, Hochberg A: Differential expression of kinase genes in primary hyperparathyroidism: adenoma versus normal and hyperplastic parathyroid tissue. Arch Pathol Lab Med; 2007 Jan;131(1):126-30
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Differential expression of kinase genes in primary hyperparathyroidism: adenoma versus normal and hyperplastic parathyroid tissue.
  • CONTEXT: Differentiation between adenoma and hyperplasia or even normal parathyroid tissue is difficult and based mainly on the surgeon's skill.
  • Exploration of genes that express differentially in these various tissues using microarrays and other sophisticated research tools will enable identification and perhaps development of new methods of perioperative diagnosis.
  • OBJECTIVE: To assemble a panel of kinase genes to differentiate parathyroid adenoma from normal and hyperplastic parathyroid tissue.
  • DESIGN: RNA was extracted from adenoma, hyperplasia, and normal parathyroid tissue and hybridized to a microarray containing 359 human cDNAs of known kinase genes.
  • RESULTS: The ratio values considered significant (<0.5 or >1.5) suggest that genes up-regulated in parathyroid adenoma are those responsible for blood vessel angiogenesis and genes belonging to the cyclin-dependent kinase inhibitor groups.
  • Genes down-regulated in parathyroid adenoma are related to cellular growth and apoptosis--genes from the mitogen-activated protein kinase group and DNA-dependent protein kinase group.
  • An interesting gene down-regulated in the parathyroid adenoma samples is related to the serine/threonine protein kinases that exert a key function in calcium handling.
  • CONCLUSIONS: The kinase genes panel presented can be used to differentiate parathyroid adenoma from normal and hyperplastic parathyroid tissue in particular when histopathology fails to provide a decisive diagnosis.
  • [MeSH-major] Adenoma / genetics. Hyperparathyroidism, Primary / genetics. Parathyroid Neoplasms / genetics. Phosphotransferases / genetics

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17227113.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] EC 2.7.- / Phosphotransferases
  •  go-up   go-down


15. Benhammou A, Meziane M, Dib N, Nazih N, Boulaadas M, Essakali L, Kzadri M: [Maxilla-mandibular brown tumors as a first sign of parathyroid adenoma]. Ann Otolaryngol Chir Cervicofac; 2009 Sep;126(4):216-20
Hazardous Substances Data Bank. PHOSPHORUS, ELEMENTAL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Maxilla-mandibular brown tumors as a first sign of parathyroid adenoma].
  • OBJECTIVES: Through a novel observation of parathyroid adenoma revealed by brown tumors of the jaws and a review of the literature, the authors describe this rare mode of primary hyperparathyroidism discovery.
  • The etiologic search consisted of a MRI of the neck, which showed a mass behind the thyroid gland, suggesting a parathyroid adenoma.
  • The diagnosis was confirmed at surgical exploration.
  • CONCLUSION: Brown tumors are a rare mode of parathyroid adenoma discovery, and the jaw location is exceptional.
  • The diagnosis is based on the parathormone rate, and radiological exams generally find the etiology.
  • Treatment is based on surgery of the parathyroid adenoma.
  • [MeSH-major] Adenoma / diagnosis. Giant Cell Tumor of Bone / diagnosis. Hyperparathyroidism, Primary / diagnosis. Mandibular Neoplasms / diagnosis. Maxillary Neoplasms / diagnosis. Parathyroid Neoplasms / diagnosis
  • [MeSH-minor] Biomarkers, Tumor / blood. Calcium / blood. Diagnosis, Differential. Female. Humans. Parathyroid Hormone / blood. Parathyroidectomy. Phosphorus / blood. Treatment Outcome. Young Adult

  • Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19524874.001).
  • [ISSN] 0003-438X
  • [Journal-full-title] Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Société d'oto-laryngologie des hôpitaux de Paris
  • [ISO-abbreviation] Ann Otolaryngol Chir Cervicofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Parathyroid Hormone; 27YLU75U4W / Phosphorus; SY7Q814VUP / Calcium
  •  go-up   go-down


16. Souza ER, Scrignoli JA, Bezerra FC, Ribeiro SL, Passos LF: Devastating skeletal effects of delayed diagnosis of complicated primary hyperparathyroidism because of ectopic adenoma. J Clin Rheumatol; 2008 Oct;14(5):281-4
Genetic Alliance. consumer health - Hyperparathyroidism, primary.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Devastating skeletal effects of delayed diagnosis of complicated primary hyperparathyroidism because of ectopic adenoma.
  • Primary hyperparathyroidism is a disease caused by exaggerated secretion of the parathyroid gland hormone, produced by an adenoma in 80% of cases.
  • Ectopic adenomas occur in a small proportion of cases.
  • Herein, the authors report a 72-year-old woman with a delayed diagnosis of primary hyperparathyroidism, produced by an intrathoracic adenoma, with a longstanding course, presenting with severe osteoporosis, multiple fractures, bone deformities, and neurologic impairments.
  • Persistent hypercalcemia, high levels of alkaline phosphatase, and parathyroid hormone were documented and a paratracheal mass was found on a helicoidal tomography of the thorax.
  • After surgical removal, the histopathological examination confirmed an ectopic adenoma of the parathyroid gland and the patient achieved some improvement in her clinical picture.
  • [MeSH-major] Adenoma / complications. Bone Diseases, Endocrine / etiology. Hyperparathyroidism, Primary / complications. Hyperparathyroidism, Primary / diagnosis. Parathyroid Neoplasms / complications
  • [MeSH-minor] Aged. Choristoma. Female. Fractures, Bone / etiology. Humans. Hypercalcemia / etiology. Nephrocalcinosis / etiology. Nephrolithiasis / etiology. Osteoporosis / etiology. Parathyroid Glands. Tracheal Diseases / etiology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18824925.001).
  • [ISSN] 1536-7355
  • [Journal-full-title] Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases
  • [ISO-abbreviation] J Clin Rheumatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


17. Erbil Y, Barbaros U, Tükenmez M, Işsever H, Salmaslioğlu A, Adalet I, Ozarmağan S, Tezelman S: Impact of adenoma weight and ectopic location of parathyroid adenoma on localization study results. World J Surg; 2008 Apr;32(4):566-71
Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Impact of adenoma weight and ectopic location of parathyroid adenoma on localization study results.
  • Although the sensitivity of preoperative localization techniques is high for solitary parathyroid adenomas, negative imaging study results are inevitable.
  • The weight and location of the parathyroid adenoma may contribute to the negative results.
  • We aimed to study the impact of adenoma weight and ectopic location of the parathyroid adenoma on ultrasonography and sestamibi scan results.
  • The patients were divided into two groups according to adenoma location.
  • Parathyroid adenoma weight and the results of imaging studies were determined in all patients.
  • Of 185 patients operated on for hyperparathyroidism, 36 (19.4%) had ectopic parathyroid glands.
  • There was a positive correlation between adenoma weight and positive imaging studies, whereas ectopic location did not correlate with negative imaging study results.
  • There was no significant difference between the ectopic adenoma ratio of patients with negative and positive imaging study results.
  • The weight of the ectopic parathyroid adenoma was significantly lower in patients with negative imaging study results than in patients with positive imaging study results (p = 0.001).
  • According to the analysis of variance, patients with higher-weight adenomas have positive imaging study results irrespective of ectopic location.
  • For both normal and ectopic adenoma locations, adenoma weight was found only to be a factor that positively influences imaging study results.
  • [MeSH-major] Adenoma / pathology. Choristoma / pathology. Parathyroid Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Analysis of Variance. Calcium / blood. Female. Follow-Up Studies. Humans. Male. Middle Aged. Organ Size. Parathyroid Hormone / blood. Retrospective Studies

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18210183.001).
  • [ISSN] 0364-2313
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Parathyroid Hormone; SY7Q814VUP / Calcium
  •  go-up   go-down


18. Harimaya A, Tsubota H, Hoki K, Sato J, Kondo A, Yamada T, Seki N, Ikeda H, Himi T: Ossifying fibroma of the mandible with primary hyperparathyroidism due to non-familial parathyroid adenoma. J Laryngol Otol; 2007 Mar;121(3):281-4
Genetic Alliance. consumer health - Hyperparathyroidism, primary.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ossifying fibroma of the mandible with primary hyperparathyroidism due to non-familial parathyroid adenoma.
  • The neoplasm sometimes presents with hyperparathyroidism, most of which cases are due to familial parathyroid tumours.
  • We report a rare case of ossifying fibroma of the mandible which showed very rapid growth and presented with primary hyperparathyroidism due to non-familial parathyroid adenoma.
  • Despite improvement of parathyroid dysfunction after removal of the parathyroid adenoma, the tumour continued to grow very aggressively.
  • [MeSH-major] Adenoma / diagnosis. Fibroma, Ossifying / diagnosis. Hyperparathyroidism, Primary / etiology. Mandibular Neoplasms / diagnosis. Parathyroid Neoplasms / diagnosis
  • [MeSH-minor] Adult. Humans. Male. Neoplasms, Multiple Primary / diagnosis

  • Genetic Alliance. consumer health - Hyperparathyroidism, familial, primary.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17134536.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  •  go-up   go-down


19. Bharadwaj R, Nema SK, Pujahari AK, Patkar N: Parathyroid adenoma with ectopic intrathymic parathyroid--a case report. Indian J Pathol Microbiol; 2005 Jan;48(1):37-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Parathyroid adenoma with ectopic intrathymic parathyroid--a case report.
  • Relevant investigations suggested a parathyroid adenoma.
  • The adenoma was excised along with a suprasternal swelling.
  • Histopathological examination confirmed the parathyroid adenoma of the mixed chief and oxyphil type.
  • An incidental finding of an intrathymic parathyroid was also made.
  • They are also subject to functional activity and hence necessitate removal by the surgeon at the first sitting, having detected these abnormally located parathyroid tissues.
  • [MeSH-major] Adenoma / pathology. Mediastinal Neoplasms / pathology. Parathyroid Glands / pathology. Parathyroid Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16758787.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  •  go-up   go-down


20. Agarwal AM, Bentz JS, Hungerford R, Abraham D: Parathyroid fine-needle aspiration cytology in the evaluation of parathyroid adenoma: cytologic findings from 53 patients. Diagn Cytopathol; 2009 Jun;37(6):407-10

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Parathyroid fine-needle aspiration cytology in the evaluation of parathyroid adenoma: cytologic findings from 53 patients.
  • This study was designed to assess the utility of fine-needle aspiration cytology (FNAC) in the preoperative localization of parathyroid adenoma (PA).
  • Parathyroid hormone (PTH) estimation was performed on the supernatant of the aspirated fluid on all cases.
  • Parathyroid cells were seen in 23 samples (40.4%).
  • Majority of the samples with parathyroid cells showed moderate cellularity with monomorphous round to slightly oval cells predominantly arranged in loose two-dimensional clusters with occasional papillary fragments.
  • In conclusion, US-guided FNAC has its limitations because of low sensitivity in primary localization of the parathyroid adenoma in cases of primary hyperparathyroidism and is not a useful mode of investigation in cases of PA.
  • [MeSH-major] Parathyroid Glands / pathology. Parathyroid Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2009 Wiley-Liss, Inc.
  • (PMID = 19283690.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Chromatin
  •  go-up   go-down


21. Doğan R, Kara M, Yazicioğlu A, Kaynaroğlu V: The use of gamma probe for the intraoperative localization of an ectopic parathyroid adenoma. Tuberk Toraks; 2009;57(2):208-11

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The use of gamma probe for the intraoperative localization of an ectopic parathyroid adenoma.
  • The most common etiologic factor of primary hyperparathyroidism is a solitary parathyroid adenoma that might be located in the mediastinum.
  • The mediastinally located ectopic parathyroid adenomas are often out of reach with a cervical incision and require a thoracic approach.
  • We present a case of 55 year-old female patient with a parathyroid adenoma located anterior to the ascending aorta within the thymus resulting in primary hyperparathyroidism.
  • The patient underwent an extended thymectomy with intraoperative use of a gamma probe as an adjunct to surgical resection which provided the accurate localization of the parathyroid adenoma.
  • Histologic diagnosis confirmed the tumor to be an ectopic parathyroid adenoma.
  • The patient showed an uneventful postoperative period with decreased levels of both calcium and parathyroid hormone.
  • We emphasize that the gamma probe serves as a very useful device to differentiate the ectopic parathyroid adenoma from surrounding tissues for complete surgical excision.
  • [MeSH-major] Adenoma / diagnosis. Choristoma / diagnosis. Mediastinal Diseases / diagnosis. Parathyroid Neoplasms / diagnosis. Sodium Pertechnetate Tc 99m
  • [MeSH-minor] Female. Humans. Hyperparathyroidism, Primary / diagnosis. Hyperparathyroidism, Primary / etiology. Middle Aged. Parathyroidectomy. Radiopharmaceuticals. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19714514.001).
  • [ISSN] 0494-1373
  • [Journal-full-title] Tüberküloz ve toraks
  • [ISO-abbreviation] Tuberk Toraks
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; A0730CX801 / Sodium Pertechnetate Tc 99m
  •  go-up   go-down


22. Malinvaud D, Potard G, Martins-Carvalho C, Jézéquel JA, Marianowski R: [Parathyroid adenoma: surgical strategy]. Ann Otolaryngol Chir Cervicofac; 2006 Dec;123(6):333-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Parathyroid adenoma: surgical strategy].
  • OBJECTIVES: The purpose of this study is to reach a better understanding in the handling of parathyroid adenomas, and to emphasize the importance of pre-operatory explorations in order to establish the best surgical approach and its cost.
  • MATERIAL AND METHODS: We are using a retrospective study of 51 patients that underwent surgery in our department between the years 1997 and 2002, for the treatment of primary hyperparathyroidism.
  • Every patient received to a pre-operatory exploration in order to localize the parathyroid tumors, including cervical echography in 51 of the cases, and a sestamibi scintigraphy in 49 of the cases.
  • [MeSH-major] Adenoma / radionuclide imaging. Adenoma / surgery. Adenoma / ultrasonography. Parathyroid Neoplasms / radionuclide imaging. Parathyroid Neoplasms / surgery. Parathyroid Neoplasms / ultrasonography

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17202992.001).
  • [ISSN] 0003-438X
  • [Journal-full-title] Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Société d'oto-laryngologie des hôpitaux de Paris
  • [ISO-abbreviation] Ann Otolaryngol Chir Cervicofac
  • [Language] fre
  • [Publication-type] Comparative Study; English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


23. Wani S, Hao Z: Atypical cystic adenoma of the parathyroid gland: case report and review of literature. Endocr Pract; 2005 Nov-Dec;11(6):389-93

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Atypical cystic adenoma of the parathyroid gland: case report and review of literature.
  • OBJECTIVE: To describe the clinical course of a patient with atypical cystic parathyroid adenoma manifesting as hypercalcemic parathyroid crisis.
  • METHODS: We present a case report and review the relevant literature on parathyroid cysts and atypical cystic parathyroid adenomas.
  • She had severe hypercalcemia (calcium level, 18.3 mg/dL) in conjunction with an elevated parathyroid hormone level of 1,472 pg/mL.
  • Intraoperatively, 25 mL of fluid was aspirated from the cystic mass, and the parathyroid hormone level in the fluid was 7,400,000 pg/mL.
  • The final pathologic diagnosis was an atypical cystic parathyroid adenoma.
  • CONCLUSION: Parathyroid cysts are uncommon and should be considered in the differential diagnosis of a neck mass.
  • Although most parathyroid cysts are nonfunctional, 10% to 15% of such cysts are functional and can rarely manifest as acute parathyroid crisis.
  • Atypical cystic parathyroid adenomas are rare and have an unpredictable clinical course.
  • Treatment options for parathyroid cysts include aspiration, injection of sclerosing agents, and surgical excision.
  • [MeSH-major] Follicular Cyst / diagnosis. Parathyroid Neoplasms / diagnosis
  • [MeSH-minor] Aged. Female. Humans. Parathyroid Hormone / blood

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16638726.001).
  • [ISSN] 1530-891X
  • [Journal-full-title] Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
  • [ISO-abbreviation] Endocr Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Parathyroid Hormone
  • [Number-of-references] 21
  •  go-up   go-down


24. Pino Rivero V, Pantoja Hernández CG, González Palomino A, Mora Santos ME, Pardo Romero R, Trinidad Ramos G, Montero García C, Blasco Huelva A: [Reoperation because of ectopic parathyroid adenoma with previous removal of lipothymoma. Importance of intraoperative PTH]. An Otorrinolaringol Ibero Am; 2006;33(6):565-71
MedlinePlus Health Information. consumer health - Thymus Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Reoperation because of ectopic parathyroid adenoma with previous removal of lipothymoma. Importance of intraoperative PTH].
  • [Transliterated title] Reintervención por adenoma ectópico de paratiroides con extirpación previa de lipotimoma. Importancia de la PTH intraoperatoria.
  • Sometimes the surgery of hyperparathyroidism is not easy and the surgical team find difficulties to locate the pathological gland or glands.
  • We report a case of primary hyperparathyroidism due to an ectopic parathyroid adenoma which required two interventions.
  • First we removed what it seems an adenoma but resulted to be a lipotimoma.
  • In the reintervention practiced one week later, having then the rapid or turbo intraoperative PTH and previous digital scintigraphy, it was possible to remove an adenoma histologically confirmed, with 3,5 cm diameter located in depth to right thyroid lobe towards the superior mediastinal straits.
  • [MeSH-major] Adenoma / surgery. Parathyroid Neoplasms / surgery. Thymoma / surgery. Thymus Neoplasms / surgery
  • [MeSH-minor] Adult. Female. Humans. Hyperparathyroidism / etiology. Hyperparathyroidism / pathology. Hyperparathyroidism / surgery. Intraoperative Care. Neoplasms, Multiple Primary. Parathyroid Glands / pathology. Parathyroid Glands / surgery. Parathyroid Hormone / blood. Parathyroidectomy. Reoperation

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17233271.001).
  • [ISSN] 0303-8874
  • [Journal-full-title] Anales otorrinolaringológicos ibero-americanos
  • [ISO-abbreviation] An Otorrinolaringol Ibero Am
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Parathyroid Hormone
  •  go-up   go-down


25. Moncet D, Isaac G, Staltari D, Tomasello A, Boronat S: [Ectopic mediastinal parathyroid adenoma. Detection with a radioisotopic probe and resolution with videothoracoscopy]. Medicina (B Aires); 2006;66(5):457-60
Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Ectopic mediastinal parathyroid adenoma. Detection with a radioisotopic probe and resolution with videothoracoscopy].
  • [Transliterated title] Adenoma paratiroideo ectópico mediastinal. Diagnóstico por sonda de detección gamma y resección por videotoracoscopia.
  • We report a 66 years old woman with a diagnosis of primary hyperparathyroidism.
  • Localization to mediastinum was obtained with parathyroid scintigraphy using 99mtc-methoxy-isobutyl-isonitrite (Tc99-MIBI).
  • An attempt to detect the precise site of the adenoma with a Tc99-MIBI probe was unsuccessful because of its proximity to the myocardium, but radioactivity was confirmed on the surgical specimen after resection.
  • [MeSH-major] Adenoma / radionuclide imaging. Hyperparathyroidism, Primary / radionuclide imaging. Mediastinal Neoplasms / radionuclide imaging. Parathyroid Neoplasms / radionuclide imaging. Radiopharmaceuticals. Technetium Tc 99m Sestamibi
  • [MeSH-minor] Aged. Calcium / blood. Calcium / urine. Female. Humans. Monitoring, Intraoperative / methods. Parathyroid Hormone / blood. Parathyroidectomy / methods. Preoperative Care. Sensitivity and Specificity. Thoracic Surgery, Video-Assisted / methods. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [ErratumIn] Medicina (B Aires). 2007;67(1):31
  • (PMID = 17137179.001).
  • [ISSN] 0025-7680
  • [Journal-full-title] Medicina
  • [ISO-abbreviation] Medicina (B Aires)
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Argentina
  • [Chemical-registry-number] 0 / Parathyroid Hormone; 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi; SY7Q814VUP / Calcium
  •  go-up   go-down


26. von Breitenbuch P, Iesalnieks I, Piso P, Schlitt HJ, Agha A: [Primary hyperparathyroidism: clinical symptoms, diagnostic significance and localisation--a retrospective analysis]. Zentralbl Chir; 2007 Dec;132(6):497-503
Genetic Alliance. consumer health - Hyperparathyroidism, primary.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary hyperparathyroidism: clinical symptoms, diagnostic significance and localisation--a retrospective analysis].
  • BACKGROUND: The primary hyperparathyroidism (pHPT) is one of the most frequent metabolic diseases.
  • Moreover, the question of the best localisation-diagnostics and the most frequent localisation of the adenoma is not yet clarified.
  • New operation strategies and more cost-efficient strategies for diagnostic and therapy could be developed due to the clinically established electrochemiluminescence immunoassay for intraoperative monitoring of intact parathyroid hormone (iPTH).
  • The best preoperative diagnostic procedure for localisation of the adenoma of the parathyroid gland, in non preoperated patients, seemed to be the combination of ultrasound and scintigraphy.
  • The most common localisation of the adenoma was caudal, on the left side.
  • Today, the combination of iPTH-monitoring and minimal invasive unilateral cervical exploration should be considered as standard in the surgery of the adrenal gland.
  • Due to our data we recommend an exploration of the left caudal parathyroid gland first if the localisation of the adenoma could not be clarified preoperatively.
  • [MeSH-major] Adenoma / diagnosis. Electrodiagnosis. Hyperparathyroidism, Primary / diagnosis. Luminescent Measurements. Monitoring, Intraoperative. Parathyroid Hormone / blood. Parathyroid Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Diagnostic Imaging. Female. Humans. Hyperparathyroidism, Secondary / blood. Hyperparathyroidism, Secondary / diagnosis. Hyperparathyroidism, Secondary / surgery. Male. Minimally Invasive Surgical Procedures. Postoperative Complications / blood. Postoperative Complications / etiology. Retrospective Studies

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [ErratumIn] Zentralbl Chir. 2008 Feb;133(1):85. Pompiliu, P [corrected to Piso, P]
  • (PMID = 18098076.001).
  • [ISSN] 0044-409X
  • [Journal-full-title] Zentralblatt für Chirurgie
  • [ISO-abbreviation] Zentralbl Chir
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Parathyroid Hormone
  •  go-up   go-down


27. Oztürk M, Ustek D, Akbas F, Kösem M, Abaci N, Alagöl F, Oztürk G, Kotan C: The presence of erythropoietin receptor in parathyroid cells. J Endocrinol Invest; 2007 Dec;30(11):RC35-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The presence of erythropoietin receptor in parathyroid cells.
  • CONTEXT: Effects of erythropoietin on parathyroid cell function has not been studied before.
  • OBJECTIVE: We aimed to demonstrate whether erythropoietin receptor present in parathyroid cells.
  • DESIGN: The specimens of normal parathyroid gland, parathyroid adenoma and hyperplasia were retrieved from our pathology archives.
  • Its density was higher in normal parathyroid, followed by parathyroid adenoma and hyperplasia.
  • CONCLUSION: Erythropoietin receptor is present in normal parathyroid, parathyroid adenoma, and hyperplasia.
  • [MeSH-major] Adenoma / metabolism. Parathyroid Glands / metabolism. Parathyroid Neoplasms / metabolism. Receptors, Erythropoietin / metabolism

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18250608.001).
  • [ISSN] 1720-8386
  • [Journal-full-title] Journal of endocrinological investigation
  • [ISO-abbreviation] J. Endocrinol. Invest.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Receptors, Erythropoietin; 11096-26-7 / Erythropoietin
  •  go-up   go-down


28. Prasad B, Fleming RM: Intrathyroidal parathyroid adenoma. Clin Nucl Med; 2005 Jul;30(7):467-9
MedlinePlus Health Information. consumer health - Thyroid Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intrathyroidal parathyroid adenoma.
  • During surgery, the patient underwent a left thyroid lobectomy for an intrathyroidal parathyroid adenoma.
  • [MeSH-major] Adenoma / diagnosis. Adenoma / surgery. Hyperparathyroidism / diagnosis. Parathyroid Neoplasms / diagnosis. Parathyroid Neoplasms / surgery. Thyroid Neoplasms / diagnosis. Thyroid Neoplasms / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15965320.001).
  • [ISSN] 0363-9762
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


29. Mallya SM, Wu HI, Saria EA, Corrado KR, Arnold A: Tissue-specific regulatory regions of the PTH gene localized by novel chromosome 11 rearrangement breakpoints in a parathyroid adenoma. J Bone Miner Res; 2010 Dec;25(12):2606-12
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tissue-specific regulatory regions of the PTH gene localized by novel chromosome 11 rearrangement breakpoints in a parathyroid adenoma.
  • Parathyroid adenomas can contain clonal rearrangements of chromosome 11 that activate the cyclin D1 oncogene through juxtaposition with the PTH gene.
  • Southern blot analyses of the parathyroid adenoma revealed rearrangement in the PTH gene locus.
  • Thus, PTH-cyclin D1 gene rearrangement breakpoints in parathyroid tumors can be located far from those previously recognized.

  • Genetic Alliance. consumer health - Chromosome 11.
  • COS Scholar Universe. author profiles.
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2010 American Society for Bone and Mineral Research.
  • [Cites] Blood. 2000 Apr 15;95(8):2691-8 [10753852.001]
  • [Cites] Nucleic Acids Res. 1990 Oct 11;18(19):5677-83 [1977134.001]
  • [Cites] J Clin Invest. 2001 May;107(9):1093-102 [11342573.001]
  • [Cites] Int J Oncol. 2002 Mar;20(3):463-6 [11836555.001]
  • [Cites] Genome Res. 2002 Apr;12(4):656-64 [11932250.001]
  • [Cites] J Mol Endocrinol. 2002 Oct;29(2):193-203 [12370121.001]
  • [Cites] Nucleic Acids Res. 2003 Jan 1;31(1):51-4 [12519945.001]
  • [Cites] Oncogene. 1991 Mar;6(3):449-53 [2011400.001]
  • [Cites] Nature. 2001 Feb 15;409(6822):860-921 [11237011.001]
  • [Cites] Nature. 1991 Apr 11;350(6318):512-5 [1826542.001]
  • [Cites] J Biol Chem. 1991 Nov 15;266(32):21903-10 [1939213.001]
  • [Cites] Proc Natl Acad Sci U S A. 1991 Nov 1;88(21):9638-42 [1682919.001]
  • [Cites] Proc Natl Acad Sci U S A. 1992 Sep 1;89(17):8097-101 [1325645.001]
  • [Cites] Leukemia. 1993 Feb;7(2):241-5 [8426477.001]
  • [Cites] Int J Cancer. 1994 May 1;57(3):353-61 [8168995.001]
  • [Cites] J Biol Chem. 1994 Nov 11;269(45):27855-62 [7961715.001]
  • [Cites] J Clin Endocrinol Metab. 1996 May;81(5):1736-9 [8626826.001]
  • [Cites] Biochemistry. 1996 Nov 26;35(47):14679-83 [8942627.001]
  • [Cites] Blood. 1997 Jan 1;89(1):349-50 [8978314.001]
  • [Cites] Cancer Genet Cytogenet. 1997 Jul 15;96(2):95-101 [9216713.001]
  • [Cites] Kidney Int. 1999 Apr;55(4):1375-83 [10201002.001]
  • [Cites] Arch Biochem Biophys. 1999 May 1;365(1):123-30 [10222046.001]
  • [Cites] Mod Pathol. 1999 Apr;12(4):412-6 [10229506.001]
  • [Cites] BMC Bioinformatics. 2005;6:79 [15799782.001]
  • [Cites] Endocrinology. 2005 Aug;146(8):3409-16 [15890770.001]
  • [Cites] Mol Endocrinol. 2005 Oct;19(10):2603-9 [15928311.001]
  • [Cites] J Clin Endocrinol Metab. 2006 Feb;91(2):580-3 [16263810.001]
  • [Cites] Genes Chromosomes Cancer. 2008 Aug;47(8):639-48 [18398822.001]
  • [Cites] Prostate. 2009 Apr 1;69(5):559-69 [19142959.001]
  • [Cites] J Bone Miner Res. 2009 Jul;24(7):1173-9 [19257819.001]
  • [Cites] Genome Res. 2003 Jan;13(1):73-80 [12529308.001]
  • [Cites] Endocrinology. 2003 Jul;144(7):3138-47 [12810570.001]
  • [Cites] J Bone Miner Res. 2003 Jul;18(7):1326-31 [12854844.001]
  • [Cites] Cancer Genet Cytogenet. 2004 Mar;149(2):114-9 [15036886.001]
  • [Cites] Cancer Genet Cytogenet. 2004 Mar;149(2):120-4 [15036887.001]
  • [Cites] Endocrinology. 2004 Jun;145(6):2713-20 [15001549.001]
  • [Cites] Proc Natl Acad Sci U S A. 1979 Oct;76(10):4981-5 [388425.001]
  • [Cites] Proc Natl Acad Sci U S A. 1981 Dec;78(12):7365-9 [6950381.001]
  • [Cites] Proc Natl Acad Sci U S A. 1983 Apr;80(8):2127-31 [6220408.001]
  • [Cites] Gene. 1984 Jun;28(3):319-29 [6086460.001]
  • [Cites] N Engl J Med. 1988 Mar 17;318(11):658-62 [3344017.001]
  • [Cites] J Clin Invest. 1989 Jun;83(6):2034-40 [2723071.001]
  • [ErratumIn] J Bone Miner Res. 2011 Feb;26(2):439
  • (PMID = 20641034.001).
  • [ISSN] 1523-4681
  • [Journal-full-title] Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
  • [ISO-abbreviation] J. Bone Miner. Res.
  • [Language] ENG
  • [Grant] United States / NIDCR NIH HHS / DE / R03 DE016337-02; United States / NIDCR NIH HHS / DE / DE016337; United States / NIDCR NIH HHS / DE / DE14773; United States / NIDCR NIH HHS / DE / DE016337-02; United States / NIDCR NIH HHS / DE / R03 DE016337; United States / Howard Hughes Medical Institute / / ; United States / NIDCR NIH HHS / DE / DE014773-05; United States / NIDCR NIH HHS / DE / K22 DE014773; United States / NIDCR NIH HHS / DE / K22 DE014773-05
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Parathyroid Hormone; 0 / Transcription Factors; 136601-57-5 / Cyclin D1
  • [Other-IDs] NLM/ NIHMS301996; NLM/ PMC3119366
  •  go-up   go-down


30. Colognesi A, de Tullio D, Messina F, Ferrocci G, Stano R, Azzena G: Primary hyperparathyroidism related to a parathyroid adenoma: the dramatic clinical evolution of a misdiagnosed patient and its surgical solution. Minerva Chir; 2006 Feb;61(1):51-6
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary hyperparathyroidism related to a parathyroid adenoma: the dramatic clinical evolution of a misdiagnosed patient and its surgical solution.
  • Primary hyperparathyroidism is a clinical condition related to an excessive and abnormally regulated secretion of parathyroid hormone (PTH) from the parathyroid glands which is responsible for an alteration of the calcium and phosphorus metabolism.
  • Parathyroid adenomas are the most important cause of primary hyperparathyroidism (80-85%).
  • A case of parathyroid adenoma observed in a patient aged 47, admitted to the Emergency Medicine Department of our Hospital with a diagnosis of hypertensive crisis, cephalea, vomiting, and a clinical history of recurrent episodes of severe abdominal and renal pain, is presented.
  • The suspect of a primary hyperparathyroidism related to a single adenoma of the parathyroid gland suggested a surgical treatment.
  • The histologycal exam reported a parathyroid adenoma with large areas with haemorrage.
  • Patients affected by primary hyperparathyroidism are often misdiagnosed because their clinical conditions can create differential diagnosis problems with other diseases.
  • [MeSH-major] Adenoma / complications. Hyperparathyroidism, Primary / etiology. Parathyroid Neoplasms / complications

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16568023.001).
  • [ISSN] 0026-4733
  • [Journal-full-title] Minerva chirurgica
  • [ISO-abbreviation] Minerva Chir
  • [Language] eng; ita
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


31. Ashkenazi D, Elmalah I, Rakover Y, Luboshitzky R: Concurrent nonfunctioning parathyroid carcinoma and parathyroid adenoma. Am J Otolaryngol; 2006 May-Jun;27(3):204-6
Genetic Alliance. consumer health - Parathyroid carcinoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Concurrent nonfunctioning parathyroid carcinoma and parathyroid adenoma.
  • Parathyroid carcinoma is a rare etiology of primary hyperparathyroidism characterized by severe clinical symptoms of hypercalcemia and markedly elevated serum parathormone levels.
  • Nonfunctioning parathyroid carcinoma is an inactive form of the disease.
  • There are less than 30 reports of nonfunctioning parathyroid carcinoma in the English literature and the association with parathyroid adenoma has not been described.
  • This report describes a patient with concurrent nonfunctioning parathyroid carcinoma and a functioning parathyroid adenoma.
  • [MeSH-major] Adenoma / surgery. Carcinoma / surgery. Neoplasms, Multiple Primary / surgery. Parathyroid Neoplasms / surgery
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Hypercalcemia / etiology. Middle Aged. Radiopharmaceuticals. Technetium Tc 99m Sestamibi

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16647986.001).
  • [ISSN] 0196-0709
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


32. Sato N, Nakagawa T, Kanno M, Nakamura Y, Kishimoto K, Imai T: [Ectopic mediastinal parathyroid adenoma]. Kyobu Geka; 2010 Aug;63(9):781-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Ectopic mediastinal parathyroid adenoma].
  • We experienced 3 surgical cases with ectopic mediastinal parathyroid adenoma.
  • All patients checked elevated serum calcium levels and parathyroid hormone levels above normal range so we diagnosed their illness as primary hyperparathyroidism.
  • To determine the location of abnormal parathyroid glands, 99mTc-methoxy-isobutyl-isonitrile (MIBI) scintigraphy, chest computed tomography (CT) scan and/or magnetic resonance imaging (MRI) were done, then posterior and anterior mediastinal tumors were revealed.
  • Especially MIBI scintigraphy was very useful as diagnostic procedure for small ectopic parathyroid adenoma.
  • It's considered that large tumor in the posterior mediastinum like case 1 is originated from upper parathyroid gland, and small tumor in the anterior mediastinum like case 2, 3 is originated from lower parathyroid gland.
  • Serum calcium and parathyroid hormone levels were normalized immediately.
  • If we can detect the accurate location of small ectopic parathyroid adenoma using some intraoperative method, the tumor is resected by less invasive procedure.
  • [MeSH-major] Adenoma / diagnosis. Mediastinal Neoplasms / diagnosis. Parathyroid Neoplasms / diagnosis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20715458.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


33. Pitukcheewanont P, Numbenjapon N, Costin G: Ectopic thymic parathyroid adenoma and vitamin D deficiency rickets: a 5-year-follow-up case report and review of literature. Bone; 2008 Apr;42(4):819-24
Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ectopic thymic parathyroid adenoma and vitamin D deficiency rickets: a 5-year-follow-up case report and review of literature.
  • Sixteen patients with primary hyperparathyroidism presenting as rickets have so far been reported in the English literature.
  • However, no report of an ectopic thymic parathyroid adenoma presenting as rickets has been published.
  • Following the intramuscular administration of 125,000 U ergocalciferol (vitamin D2), he developed hypercalcemia with persistently elevated parathyroid hormone (PTH) levels suggestive of primary hyperparathyroidism.
  • Sestamibi scan demonstrated significant uptake in the superior chest, without uptake at the normal parathyroid glands location.
  • Surgical exploration revealed normal parathyroid glands and a thymic mass, which was removed and confirmed by pathology to be a parathyroid adenoma.
  • To our knowledge, this is the first case of an ectopic thymic parathyroid adenoma in a patient presenting with rickets.
  • Our patient demonstrates that hyperparathyroidism-induced hypercalcemia may be masked by severe vitamin D deficiency.
  • Prolonged treatment with ergocalciferol after removal of the parathyroid adenoma was necessary to normalize iPTH and replenish vitamin D store.
  • [MeSH-major] Parathyroid Neoplasms / pathology. Rickets. Vitamin D Deficiency

  • Genetic Alliance. consumer health - Rickets.
  • MedlinePlus Health Information. consumer health - Rickets.
  • MedlinePlus Health Information. consumer health - Vitamin D Deficiency.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18242158.001).
  • [ISSN] 8756-3282
  • [Journal-full-title] Bone
  • [ISO-abbreviation] Bone
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Ergocalciferols; SY7Q814VUP / Calcium
  •  go-up   go-down


34. Fernandez-Ranvier GG, Khanafshar E, Jensen K, Zarnegar R, Lee J, Kebebew E, Duh QY, Clark OH: Parathyroid carcinoma, atypical parathyroid adenoma, or parathyromatosis? Cancer; 2007 Jul 15;110(2):255-64
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Parathyroid carcinoma, atypical parathyroid adenoma, or parathyromatosis?
  • BACKGROUND: Parathyroid carcinoma, atypical parathyroid adenoma, and parathyromatosis can be differentiated relatively easily from typical parathyroid adenomas, but distinguishing them from each other is more difficult.
  • METHODS: A retrospective study of 28 consecutive patients with parathyroid carcinoma, 7 patients with atypical parathyroid adenoma, and 13 patients with parathyromatosis who were treated at the University of California at San Francisco Medical Center between 1966 and 2005 was performed.
  • RESULTS: Parathyroid carcinoma (19 of 28 patients) and atypical adenoma (4 of 7 patients) were significantly more common in men, whereas parathyromatosis was more common in women (10 of 13 patients) (P = .02).
  • A palpable neck mass and hoarseness were almost exclusively present in patients with parathyroid carcinoma.
  • Prior to the first parathyroid surgery, patients with parathyroid carcinoma were found to have higher blood calcium levels (>/=14 mg/dL in 16 of 26 patients [62%]), whereas only 1 of 6 patients with atypical adenoma (17%) and no patients with parathyromatosis were found to have profound hypercalcemia (P < .01).
  • Intraoperatively, patients with parathyroid carcinoma and atypical adenoma presented with single lesions, whereas patients with parathyromatosis had multiple small lesions.
  • Histopathologic findings were well defined in parathyroid carcinoma, but some findings overlapped in the 3 tumors studied.
  • CONCLUSIONS: Patients with parathyroid carcinoma often differ from those with atypical parathyroid adenoma or parathyromatosis at the time of presentation because patients with parathyroid carcinoma have more profound hypercalcemia as well as invasive tumors.
  • [MeSH-major] Adenoma / pathology. Carcinoma / pathology. Hyperparathyroidism / pathology. Parathyroid Neoplasms / pathology

  • Genetic Alliance. consumer health - Parathyroid carcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17559137.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


35. Chan AP, Wan IY, Wong RH, Hsin MK, Underwood MJ: Robot-assisted excision of ectopic mediastinal parathyroid adenoma. Asian Cardiovasc Thorac Ann; 2010 Feb;18(1):65-7
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Robot-assisted excision of ectopic mediastinal parathyroid adenoma.
  • Robot-assisted excision of an ectopic parathyroid adenoma in the superior mediastinum was performed in a 57-year-old man.
  • Identification of the ectopic parathyroid adenoma was facilitated by the 3-dimensional images of the da Vinci robotic system, and resection was achieved using EndoWrist instruments.
  • Robot-assisted excision of parathyroid adenoma located in the relatively inaccessible superior mediastinum proved to be feasible.
  • [MeSH-major] Adenoma / surgery. Mediastinum / surgery. Parathyroid Neoplasms / surgery. Parathyroidectomy / methods. Robotics / methods

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20124300.001).
  • [ISSN] 1816-5370
  • [Journal-full-title] Asian cardiovascular & thoracic annals
  • [ISO-abbreviation] Asian Cardiovasc Thorac Ann
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
  •  go-up   go-down


36. Smayra T, Abi Khalil S, Abboud B, Halabi G, Slaba S: [Unusual location of a parathyroid adenoma: the carotid sheath]. J Radiol; 2006 Jan;87(1):59-61

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Unusual location of a parathyroid adenoma: the carotid sheath].
  • [Transliterated title] Localisation atypique d'un adénome parathyroïdien: la gaine carotidienne.
  • We report the imaging features of an occult parathyroid adenoma with unusual location in the carotid sheath.
  • Our patient presented with primary hyperparathyroidism.
  • Venous sampling of the neck confirmed the left location of the adenoma and a third surgical intervention found the adenoma embedded in the left carotid sheath.
  • This is an unusual case of parathyroid adenoma that necessitated the use of several imaging techniques.
  • [MeSH-major] Adenoma / diagnosis. Carotid Artery, Common / pathology. Parathyroid Neoplasms / diagnosis. Vascular Neoplasms / diagnosis
  • [MeSH-minor] Adult. Angiography, Digital Subtraction. Female. Humans. Hyperparathyroidism / diagnosis. Magnetic Resonance Imaging. Neck Dissection. Thyroid Gland / blood supply. Thyroidectomy. Tomography, X-Ray Computed

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16415782.001).
  • [ISSN] 0221-0363
  • [Journal-full-title] Journal de radiologie
  • [ISO-abbreviation] J Radiol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  •  go-up   go-down


37. Bal A, Sachdeva MU, Joshi K, Behera A, Arora S, Gupta S: Non-functioning mediastinal parathyroid adenoma with sarcoid-like granulomatous lymphadenopathy. APMIS; 2007 Jun;115(6):784-8
MedlinePlus Health Information. consumer health - Lymphatic Diseases.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Non-functioning mediastinal parathyroid adenoma with sarcoid-like granulomatous lymphadenopathy.
  • Non-secretory parathyroid adenomas arising in an ectopic parathyroid gland are rare.
  • We report a case of non-functioning anterior mediastinal parathyroid adenoma associated with mediastinal lymphadenopathy caused by sarcoid-like granulamatous inflammation.
  • [MeSH-major] Adenoma / pathology. Lymphatic Diseases / complications. Mediastinal Neoplasms / pathology. Parathyroid Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17550391.001).
  • [ISSN] 0903-4641
  • [Journal-full-title] APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
  • [ISO-abbreviation] APMIS
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  •  go-up   go-down


38. Muthukrishnan J, Verma A, Modi KD, Kumaresan K, Jha S: Ectopic parathyroid adenoma--the hidden culprit. J Assoc Physicians India; 2007 Jul;55:515-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ectopic parathyroid adenoma--the hidden culprit.
  • Primary Hyperparathyroidism is known to present with protean manifestations leading to misdiagnosis in the initial stages of the disease.
  • Inability to locate the adenoma in an ectopic parathyroid gland may further delay the diagnosis of these cases.
  • Aberrant migration during development may lead to intrathyroidal or other ectopic locations of parathyroid glands.
  • Similarity in cytological picture between thyroids and parathyroids may further complicate diagnosis by fine needle aspiration cytology.
  • We encountered three such cases with the parathyroid gland adenomas in ectopic locations in which pre-operative nuclear imaging played a major role.
  • [MeSH-major] Hyperparathyroidism, Primary / diagnosis. Parathyroid Glands / pathology. Parathyroid Neoplasms / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Middle Aged

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17907504.001).
  • [ISSN] 0004-5772
  • [Journal-full-title] The Journal of the Association of Physicians of India
  • [ISO-abbreviation] J Assoc Physicians India
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  •  go-up   go-down


39. Abbas F, Biyabani SR, Memon A, Talati J: Mediastinal parathyroid adenoma causing primary hyperparathyroidism. J Pak Med Assoc; 2007 Feb;57(2):93-5
MedlinePlus Health Information. consumer health - Thymus Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mediastinal parathyroid adenoma causing primary hyperparathyroidism.
  • An ectopically placed parathyroid adenoma in the anterior mediastinum is a rare cause of persistent or recurrent primary hyperparathyroidism (PHPT) and is recognized as an important cause of failed primary neck exploration.
  • In 2 cases, the offending adenoma could be removed at first exploration whereas in the 3rd case, it was successfully removed with mediastinal exploration after 2 failed neck explorations.
  • In established cases of PHPT with equivocal preoperative localization studies or negative neck explorations, an ectopically placed parathyroid adenoma should be considered and once localized, should be surgically removed for cure.
  • [MeSH-major] Adenoma / pathology. Hyperparathyroidism, Primary / etiology. Parathyroid Neoplasms / pathology. Thymus Neoplasms / pathology

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17370794.001).
  • [ISSN] 0030-9982
  • [Journal-full-title] JPMA. The Journal of the Pakistan Medical Association
  • [ISO-abbreviation] J Pak Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
  •  go-up   go-down


40. Koksal H, Kurukahvecioglu O, Yazicioglu MO, Taneri F: Primary hyperparathyroidism due to parathyroid adenoma. Saudi Med J; 2006 Jul;27(7):1034-7
Hazardous Substances Data Bank. PHOSPHORUS, ELEMENTAL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary hyperparathyroidism due to parathyroid adenoma.
  • OBJECTIVE: To evaluate the clinical characteristics and outcome of patients with parathyroid adenoma.
  • METHODS: We diagnosed and operated 54 patients with primary hyperparathyroidism in the Faculty of Medicine, Gazi University, Turkey from January 2000 to December 2004.
  • In this study, 52 (96.2%) of these patients who had parathyroid adenoma were retrospectively evaluated.
  • RESULTS: There were 46 female, and 6 male patients with a median age of 54.5 years (range, 18-87 years) at diagnosis.
  • Preoperative mean serum level of calcium was 11.09 +/- 0.9 mg/dL, while phosphorus was 2.3 +/- 0.5 mg/mL, and parathyroid hormone (PTH) was 338.99 +/- 416.43 pg/ml.
  • Ultrasound imaging revealed parathyroid adenoma in 38 of the 52 patients (73%), while 27% of the patients were normal.
  • In 29 (69%) of the 42 patients who had sestamibi scanning, results revealed parathyroid adenoma and in the others (31%), sestamibi scanning was normal.
  • CONCLUSION: Parathyroid adenoma is the most common cause of primary hyperparathyroidism.
  • Preoperative serum calcium and PTH levels are the most useful parameters for diagnosis.
  • [MeSH-major] Adenoma / complications. Hyperparathyroidism, Primary / etiology. Parathyroid Neoplasms / complications
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Calcium / blood. Female. Humans. Male. Middle Aged. Parathyroid Hormone / blood. Phosphorus / blood. Retrospective Studies

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Saudi Med J. 2007 Feb;28(2):305; author reply 305-6 [17268723.001]
  • (PMID = 16830026.001).
  • [ISSN] 0379-5284
  • [Journal-full-title] Saudi medical journal
  • [ISO-abbreviation] Saudi Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Saudi Arabia
  • [Chemical-registry-number] 0 / Parathyroid Hormone; 27YLU75U4W / Phosphorus; SY7Q814VUP / Calcium
  •  go-up   go-down


41. Huang SC, Wu VC, Chou G, Huang TY, Lin SY, Sheu WH: Benign parathyroid adenoma presenting with unusual parathyroid crisis, anemia and myelofibrosis. J Formos Med Assoc; 2007 Feb;106(2 Suppl):S13-6
MedlinePlus Health Information. consumer health - Anemia.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign parathyroid adenoma presenting with unusual parathyroid crisis, anemia and myelofibrosis.
  • Although the clinical symptoms of patients with benign parathyroid adenoma are usually nonspecific and benign, a malignant presentation of the benign disease may sometimes occur.
  • Acute hypercalcemic crisis manifested and primary hyperparathyroidism was diagnosed together with myelofibrosis on account of the result of bone marrow biopsy.
  • Excision of a parathyroid adenoma was performed, and the anemia and bone marker regressed later.
  • These findings suggested that benign parathyroid adenoma may mimic the clinical presentation of parathyroid carcinoma, releasing excess parathyroid hormone and resulting in hyperparathyroid crisis.
  • In addition, primary hyperparathyroidism can be associated with anemia and myelofibrosis.

  • Genetic Alliance. consumer health - Anemia.
  • Genetic Alliance. consumer health - Myelofibrosis.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17493890.001).
  • [ISSN] 0929-6646
  • [Journal-full-title] Journal of the Formosan Medical Association = Taiwan yi zhi
  • [ISO-abbreviation] J. Formos. Med. Assoc.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
  •  go-up   go-down


42. Varoglu AO, Aksoy A, Varoglu E: Parathyroid adenoma presenting as tetraparesia. Neuro Endocrinol Lett; 2010;31(4):451-3
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Parathyroid adenoma presenting as tetraparesia.
  • OBJECTIVE: Parathyroid adenomas (PA) are benign tumors.
  • We report an unusual case of delayed diagnosis of a PA and concomitant Vitamin D deficiency presenting as tetraparesia.
  • RESULTS: Laboratory investigations showed the following: creatinine phosphokinase (CK): 37 IU/L (15-130), calcium (Ca): 11.5 mg/dL (9-11), phosphorus (P): 1.5 mg/dL (2.5-5), parathyroid hormone (PTH): 736.1 pq/mL (15-65), 25-hydroxyvitamin D (25-OHvit D): 4 ng/mL (11-43), and alkaline phosphatase (ALP): 1029.5 lU (64-300).
  • Parathyroid scintigraphy revealed PA.
  • CONCLUSION: We suggest that the physicians always keep in mind the primary hyperparathyroidism (HPT) and concomitant Vitamin D deficiency in the differential diagnosis of hypercalcemia when facing atypical neurological symptoms such as tetraparesia.
  • [MeSH-major] Adenoma / complications. Parathyroid Neoplasms / complications. Quadriplegia / etiology. Vitamin D Deficiency / complications

  • MedlinePlus Health Information. consumer health - Vitamin D Deficiency.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20802446.001).
  • [ISSN] 0172-780X
  • [Journal-full-title] Neuro endocrinology letters
  • [ISO-abbreviation] Neuro Endocrinol. Lett.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Sweden
  • [Chemical-registry-number] 1406-16-2 / Vitamin D
  •  go-up   go-down


43. Bäcklund LM, Grandér D, Brandt L, Hall P, Ekbom A: Parathyroid adenoma and primary CNS tumors. Int J Cancer; 2005 Mar 1;113(6):866-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Parathyroid adenoma and primary CNS tumors.
  • Hyperparathyroidism onset at a young age is one feature in multiple endocrine neoplasia (MEN) type 1 and MEN type 2A cancer syndromes.
  • To determine if there is an association between parathyroid adenomas and CNS tumors, we used Swedish registry data to identify all individuals operated on for parathyroid adenomas between 1958-99 (n = 12,468).
  • There were 70 observed cases of a CNS tumor diagnosed after a parathyroid adenoma, to be compared to 35 expected (standard incidence ratio [SIR] = 2.0; 95% confidence interval [CI] = 1.5-2.5).
  • [MeSH-major] Adenoma / epidemiology. Central Nervous System Neoplasms / epidemiology. Parathyroid Neoplasms / epidemiology
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Female. Humans. Male. Middle Aged. Neoplasms, Second Primary / epidemiology. Registries. Retrospective Studies. Sweden / epidemiology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2004 Wiley-Liss, Inc.
  • (PMID = 15515018.001).
  • [ISSN] 0020-7136
  • [Journal-full-title] International journal of cancer
  • [ISO-abbreviation] Int. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


44. Harris B, Bailey D, Roach P, Marshman D, McElduff A, King G: Use of fusion imaging to localize an ectopic thoracic parathyroid adenoma. Ann Thorac Surg; 2006 Aug;82(2):719-21
MedlinePlus Health Information. consumer health - Tumors and Pregnancy.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Use of fusion imaging to localize an ectopic thoracic parathyroid adenoma.
  • We report the use of fused computed tomography and single photon emission computed tomography parathyroid (99m technetium)-sestamibi images to localize an ectopic parathyroid adenoma.
  • [MeSH-major] Adenoma / radionuclide imaging. Choristoma / radionuclide imaging. Mediastinal Diseases / radionuclide imaging. Parathyroid Neoplasms / radionuclide imaging. Pregnancy Complications, Neoplastic / radionuclide imaging. Technetium Tc 99m Sestamibi. Tomography, Emission-Computed, Single-Photon

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16863795.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


45. Kiverniti E, Kazi R, Rhys-Evans P, Nippah R: Airway obstruction due to giant non-parathyroid hormone-producing parathyroid adenoma. J Cancer Res Ther; 2008 Oct-Dec;4(4):197-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Airway obstruction due to giant non-parathyroid hormone-producing parathyroid adenoma.
  • Parathyroid gland tumors are unusual in the differential diagnosis of mediastinal tumors.
  • The eventual diagnosis on histology was parathyroid adenoma.
  • The patient had no clinical evidence of metabolic abnormalities and her pre- and postoperative calcium and postoperative parathyroid hormone (PTH) levels were within normal limits.
  • This case poses the interesting question of whether identification of elevated PTH levels is an absolute prerequisite for diagnosing parathyroid adenomas.
  • [MeSH-major] Parathyroid Neoplasms / complications
  • [MeSH-minor] Adenoma. Adult. Airway Obstruction. Esophagus / metabolism. Female. Humans. Mediastinal Neoplasms / metabolism. Medical Oncology / methods. Parathyroid Hormone / metabolism. Tomography, X-Ray Computed / methods. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19052395.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Parathyroid Hormone
  •  go-up   go-down


46. Kim SC, Kim S, Inabnet WB, Krynyckyi BR, Machac J, Kim CK: Appearance of descended superior parathyroid adenoma on SPECT parathyroid imaging. Clin Nucl Med; 2007 Feb;32(2):90-3
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Appearance of descended superior parathyroid adenoma on SPECT parathyroid imaging.
  • An ectopic superior parathyroid adenoma (SPA) descends inferoposteriorly and can migrate to the posterior mediastinum.
  • It often appears on sestamibi planar parathyroid imaging as an inferior lesion, which can be misleading to inexperienced surgeons.
  • METHODS: Sestamibi SPECT imaging studies performed on 103 patients who had parathyroid adenomas with their origin and locations confirmed by surgery and histology were retrospectively reviewed.
  • Abnormal foci seen on the SPECT images were grouped as to location relative to the thyroid gland as superior (S), middle (M), and inferior (I).
  • Ten foci were at the M level, including 6 SPA and 4 inferior parathyroid adenomas (IPA).
  • [MeSH-major] Adenoma / pathology. Adenoma / radionuclide imaging. Parathyroid Neoplasms / pathology. Parathyroid Neoplasms / radionuclide imaging. Tomography, Emission-Computed, Single-Photon

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17242559.001).
  • [ISSN] 0363-9762
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


47. Hultin H, Hellman P, Lundgren E, Olovsson M, Ekbom A, Rastad J, Montgomery SM: Association of parathyroid adenoma and pregnancy with preeclampsia. J Clin Endocrinol Metab; 2009 Sep;94(9):3394-9
MedlinePlus Health Information. consumer health - Tumors and Pregnancy.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Association of parathyroid adenoma and pregnancy with preeclampsia.
  • OBJECTIVE: Case reports have described associations between calcium metabolism disturbances and primary hyperparathyroidism with preeclampsia, suggesting parathyroid involvement in preeclampsia etiology.
  • This study examines whether parathyroid adenoma, the main cause of hyperparathyroidism, diagnosed and treated before pregnancy is associated with preeclampsia.
  • DESIGN: We conducted a register-based study to assess the association between parathyroid adenoma and subsequent preeclampsia.
  • POPULATION: The study population included 52 women with a diagnosis of parathyroid adenoma and 519 without, all of whom had a subsequent singleton pregnancy between 1973 and 1997.
  • METHODS: We performed a conditional logistic regression investigating the association of parathyroid adenoma with subsequent preeclampsia in the first singleton pregnancy with adjustment for potential confounding factors.
  • MAIN OUTCOME MEASURE: The main outcome was a diagnosis of preeclampsia that does not include women with prior chronic hypertension.
  • To ensure that treatment of parathyroid adenoma was completed before pregnancy, those with a diagnosis of parathyroid adenoma made less than 2 yr before delivery (and the matched comparison women) were excluded.
  • RESULTS: Statistically, parathyroid adenoma prior to delivery is significantly (P < 0.001) associated with preeclampsia, producing an adjusted odds ratio of 6.89 (95% confidence interval, 2.30, 20.58).
  • CONCLUSION: A history of parathyroid adenoma should be viewed as a risk for preeclampsia.
  • [MeSH-major] Adenoma / complications. Parathyroid Neoplasms / complications. Pre-Eclampsia / etiology. Pregnancy Complications, Neoplastic
  • [MeSH-minor] Adult. Female. Humans. Parathyroid Hormone / blood. Pregnancy

  • Genetic Alliance. consumer health - Preeclampsia.
  • Genetic Alliance. consumer health - Pregnancy.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19531594.001).
  • [ISSN] 1945-7197
  • [Journal-full-title] The Journal of clinical endocrinology and metabolism
  • [ISO-abbreviation] J. Clin. Endocrinol. Metab.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Parathyroid Hormone
  •  go-up   go-down


48. Shirzad N, Tehrani MR, Soltani A: A rare association of hyperparathyroidism and Turner's syndrome--a case report. Endokrynol Pol; 2008 May-Jun;59(3):232-4
MedlinePlus Health Information. consumer health - Turner Syndrome.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A rare association of hyperparathyroidism and Turner's syndrome--a case report.
  • After primary evaluation, she underwent treatment with calcium and vitamin D supplement with the diagnosis of osteomalacia in Turner's syndrome.
  • The rise of serum calcium during medical therapy, which was an unusual finding, attracted the clinician's attention to another underlying disorder.
  • Further evaluation revealed primary hyperparathyroidism due to an adenoma of the parathyroid gland.
  • Even though this is a rare diagnosis, its presence should be considered in any patient with Turner's syndrome presenting with severe osteoporosis and a rise in serum calcium during treatment.
  • [MeSH-major] Adenoma / diagnosis. Hyperparathyroidism / etiology. Parathyroid Neoplasms / diagnosis. Turner Syndrome / complications

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18615398.001).
  • [ISSN] 0423-104X
  • [Journal-full-title] Endokrynologia Polska
  • [ISO-abbreviation] Endokrynol Pol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
  •  go-up   go-down


49. Hamidi S, Hedayat A, Esfahanian F, Kamalian N: Distribution of solitary parathyroid adenoma over the parathyroid glands and its surgical management. J Coll Physicians Surg Pak; 2007 Oct;17(10):619-21

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Distribution of solitary parathyroid adenoma over the parathyroid glands and its surgical management.
  • OBJECTIVE: To determine the distribution of solitary parathyroid adenoma over the parathyroid glands in a group of patients with primary hyperparathyroidism Design: A case-series.
  • PATIENTS AND METHODS: A retrospective review of surgery reports of 118 patients with primary hyperparathyroidism was performed.
  • All of the patients had solitary parathyroid adenoma and the anatomical location of each adenoma was clearly defined during operation.
  • RESULTS: The distribution of adenomas over the superior and inferior parathyroid glands showed a significant higher incidence of adenoma in the lower parathyroids (p < 0.001).
  • The right to left distribution of adenomas was not significant (p=0.4).
  • CONCLUSION: Surgical exploration for primary hyperparathyroidism should be initiated from the lower parathyroid glands provided that pre-operative localization scans are not helpful.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17999854.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Pakistan
  •  go-up   go-down


50. Al-Mashat F, Sibiany A, Faleh D, Kary K, Alfi AY, El-Lakany MM: Mediastinal parathyroid adenoma. Saudi J Kidney Dis Transpl; 2009 Sep;20(5):826-30
Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mediastinal parathyroid adenoma.
  • We present two cases that developed clinical, biochemical and radiological evidences of primary and secondary hyperparathyroidism.
  • In the first case the adenoma was removed through a transcervical incision and in the second case the supernumerary adenoma was removed through sternotomy.
  • [MeSH-major] Adenoma / surgery. Parathyroid Neoplasms / surgery. Parathyroidectomy. Sternum / surgery
  • [MeSH-minor] Adult. Biomarkers / blood. Calcium / blood. Female. Humans. Hyperparathyroidism, Primary / etiology. Hyperparathyroidism, Secondary / etiology. Magnetic Resonance Imaging. Middle Aged. Parathyroid Hormone / blood. Radiopharmaceuticals. Technetium. Technetium Tc 99m Sestamibi. Thallium Radioisotopes. Treatment Outcome

  • Hazardous Substances Data Bank. TECHNETIUM, ELEMENTAL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19736482.001).
  • [ISSN] 1319-2442
  • [Journal-full-title] Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia
  • [ISO-abbreviation] Saudi J Kidney Dis Transpl
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Saudi Arabia
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Parathyroid Hormone; 0 / Radiopharmaceuticals; 0 / Thallium Radioisotopes; 7440-26-8 / Technetium; 971Z4W1S09 / Technetium Tc 99m Sestamibi; SY7Q814VUP / Calcium
  •  go-up   go-down


51. Vijayakumar V, Anderson ME: Detection of ectopic parathyroid adenoma by early Tc-99m sestamibi imaging. Ann Nucl Med; 2005 Apr;19(2):157-9
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Detection of ectopic parathyroid adenoma by early Tc-99m sestamibi imaging.
  • Localization of Tc-99m sestamibi (MIBI) by parathyroid adenomas (PA) is well known.
  • However, the washout of MIBI from ectopic parathyroid adenoma (EPA) in not well reported.
  • [MeSH-major] Adenoma / radionuclide imaging. Choristoma / radionuclide imaging. Mediastinal Diseases / radionuclide imaging. Parathyroid Neoplasms / radionuclide imaging. Technetium Tc 99m Sestamibi

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15909497.001).
  • [ISSN] 0914-7187
  • [Journal-full-title] Annals of nuclear medicine
  • [ISO-abbreviation] Ann Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


52. Gurney TA, Orloff LA: Otolaryngologist-head and neck surgeon-performed ultrasonography for parathyroid adenoma localization. Laryngoscope; 2008 Feb;118(2):243-6
MedlinePlus Health Information. consumer health - Head and Neck Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Otolaryngologist-head and neck surgeon-performed ultrasonography for parathyroid adenoma localization.
  • OBJECTIVE: To demonstrate the efficacy of otolaryngologist-head and neck surgeon-performed ultrasonography (US) for the preoperative localization of parathyroid adenomas.
  • METHODS: A retrospective chart review of all patients evaluated by office-based US for the localization of surgery-proven parathyroid adenomas from October 2004 through February 2007.
  • The size range of adenomas detected as measured by US was 0.5 to 2.7 cm.
  • A total of 30 parathyroid adenomas were found.
  • US identified 90% of the parathyroid adenomas to the correct side, left or right.
  • In addition, US localized the parathyroid adenomas to the correct quadrant, superior or inferior, 83% of the time.
  • For comparison, sestamibi scans performed on the same patients localized the parathyroid adenoma to the correct side only 71% of the time and to the correct quadrant 61% of the time.
  • CONCLUSIONS: Otolaryngologist-head and neck surgeon-performed US can accurately identify the location of parathyroid adenomas and is a useful tool for preoperative planning.
  • [MeSH-major] Head and Neck Neoplasms / ultrasonography. Otolaryngology / methods. Parathyroid Neoplasms / ultrasonography. Preoperative Care
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Diagnosis, Differential. Female. Humans. Hyperparathyroidism / surgery. Male. Middle Aged. Retrospective Studies

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18090868.001).
  • [ISSN] 0023-852X
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


53. Fallone E, Bourne PA, Watson TJ, Ghossein RA, Travis WD, Xu H: Ectopic (mediastinal) parathyroid adenoma with prominent lymphocytic infiltration. Appl Immunohistochem Mol Morphol; 2009 Jan;17(1):82-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ectopic (mediastinal) parathyroid adenoma with prominent lymphocytic infiltration.
  • Parathyroid adenoma with prominent lymphocytic infiltrates is very rare, with only 8 previously reported cases in the English scientific literature.
  • Cases with prominent lymphocytic infiltrates of ectopic (mediastinal) parathyroid adenomas have not been reported.
  • The prominent lymphocytic infiltration may make the diagnosis difficult on frozen sections, even on permanent histologic sections.
  • We herein describe a case of ectopic (mediastinal) parathyroid adenoma with prominent lymphocytic infiltration in a 29-year-old man with hyperparathyroidism for 4 years.
  • Immunohistochemical studies were important in making such a diagnosis.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19115487.001).
  • [ISSN] 1533-4058
  • [Journal-full-title] Applied immunohistochemistry & molecular morphology : AIMM
  • [ISO-abbreviation] Appl. Immunohistochem. Mol. Morphol.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


54. Kaushal DK, Mishra A, Mittal N, Bordoloi JK: Successful removal of intrathyroidal parathyroid adenoma diagnosed and accurately located preoperatively by parathyroid scintigraphy (SPECT-CT). Indian J Nucl Med; 2010 Apr;25(2):62-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Successful removal of intrathyroidal parathyroid adenoma diagnosed and accurately located preoperatively by parathyroid scintigraphy (SPECT-CT).
  • We describe the case of a large intrathyroidal parathyroid adenoma in a 46-year-old woman who had a history of recently diagnosed hypercalcaemia and a 2-year history of an asymptomatic enlargement of the right lobe of the thyroid.
  • This rare case highlights the potential difficulties that can arise in the evaluation of hyperparathyroidism, especially in cases of multinodular goiter.
  • In some cases, including this one, even a thorough preoperative evaluation that includes radiological studies (ultrasonography and computed tomography [CT]) may not allow for a definitive preoperative diagnosis due to limited sensitivity, especially in multinodular goiter.
  • The overlapping histological features between thyroid and parathyroid lesions can also be problematic at the time of the intraoperative frozen-section evaluation.
  • We present a case in which, with parathyroid scintigraphy and combination of structural and functional imaging (SPECT-CT), we could accurately locate the intrathyroidal parathyroid adenoma in a patient with multinodular goiter.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21188066.001).
  • [ISSN] 0974-0244
  • [Journal-full-title] Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India
  • [ISO-abbreviation] Indian J Nucl Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3003286
  • [Keywords] NOTNLM ; Intrathyroidal parathyroid adenoma
  •  go-up   go-down


55. Rajagopalan MS, Narla VV, Kanderi T, Muthukrishnan A: Para-hyoid ectopic parathyroid adenoma localized by Tc-99m MIBI SPECT. Clin Nucl Med; 2008 Dec;33(12):880-1

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Para-hyoid ectopic parathyroid adenoma localized by Tc-99m MIBI SPECT.
  • A 64-year-old woman with a history of I-131 ablation for Graves hyperthyroidism and bilateral parathyroid exploration with resection of a left inferior parathyroid adenoma presented 2 years after surgery with marked fatigue, irritability, and joint pain.
  • Laboratory testing revealed an elevated calcium and parathyroid hormone levels suspicious for hyperparathyroidism.
  • The ultrasound indicated no evidence of a parathyroid adenoma.
  • Tc-99m-MIBI SPECT demonstrated a focus of uptake posteroinferior to the right submandibular gland, suspicious for a parathyroid adenoma.
  • Repeat ultrasound and CT confirmed the presence of a para-hyoid adenoma inferior to the right submandibular gland.
  • [MeSH-major] Choristoma / pathology. Choristoma / radionuclide imaging. Hyoid Bone / pathology. Hyoid Bone / radionuclide imaging. Parathyroid Neoplasms / radionuclide imaging. Technetium Tc 99m Sestamibi. Tomography, Emission-Computed, Single-Photon

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19033797.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


56. Akinci B, Demir T, Yener S, Comlekci A, Binicier O, Ozdogan O, Sevinc A, Kocdor MA, Bayraktar F, Canda T, Yesil S: Beneficial effect of endocrinologist-performed ultrasonography on preoperative parathyroid adenoma localization. Endocr Pract; 2009 Jan-Feb;15(1):17-23

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Beneficial effect of endocrinologist-performed ultrasonography on preoperative parathyroid adenoma localization.
  • OBJECTIVE: To evaluate whether endocrinologist-performed ultrasonography improves the localization of parathyroid adenomas in patients with primary hyperparathyroidism.
  • METHODS: We performed a retrospective analysis of consecutive patients with primary hyperparathyroidism due to a single adenoma who underwent surgery at the Dokuz Eylul University Hospital in Izmir, Turkey, between January 2000 and January 2008.
  • Data regarding the localization of adenomas were obtained from surgical reports.
  • Parathyroid ultrasonography was performed by a staff radiologist between January 2000 and December 2004.
  • Beginning January 2005, parathyroid ultrasonography was performed blindly by an endocrinologist in addition to the staff radiologist.
  • RESULTS: A total of 156 patients with primary hyperparathyroidism due to a single adenoma were included.
  • Ultrasonography localized 102 parathyroid adenomas (65%).
  • Endocrinologist-performed ultrasonography localized the adenoma correctly in 19 patients for whom the staff radiologist had reported a negative or unsuccessful localization.
  • When ultrasonography results were combined with the MIBI scan findings, parathyroid adenomas were again more likely to be localized in patients who underwent operation after January 2005 and thus had endocrinologist-performed ultrasonography.
  • CONCLUSION: Our results suggest that endocrinologist-performed ultrasonography improves the preoperative localization of parathyroid adenoma.
  • [MeSH-major] Adenoma / ultrasonography. Clinical Competence. Parathyroid Neoplasms / ultrasonography. Ultrasonography, Doppler, Color / standards

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [ErratumIn] Endocr Pract. 2009 Nov-Dec;15(7):768. Secil, Mustafa [removed]
  • (PMID = 19211392.001).
  • [ISSN] 1934-2403
  • [Journal-full-title] Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
  • [ISO-abbreviation] Endocr Pract
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


57. Singh N, Krishna BA: Role of radionuclide scintigraphy in the detection of parathyroid adenoma. Indian J Cancer; 2007 Jan-Mar;44(1):12-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Role of radionuclide scintigraphy in the detection of parathyroid adenoma.
  • BACKGROUND: Preoperative detection of parathyroid adenoma is a diagnostic challenge.
  • AIM: We undertook a study to assess the role of radionuclide scanning in suspected cases of parathyroid adenomas.
  • The parathyroid scan was performed using either of the two techniques - Dual isotope subtraction or Sestamibi washout technique.
  • CONCLUSION: We conclude that parathyroid scintigraphy is a reliable and sensitive technique in the preoperative detection of parathyroid adenomas and should be the first choice of imaging modality in suspicion of parathyroid adenoma.
  • [MeSH-major] Adenoma / radionuclide imaging. Parathyroid Neoplasms / radionuclide imaging. Radiopharmaceuticals. Technetium Tc 99m Sestamibi

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17401219.001).
  • [ISSN] 0019-509X
  • [Journal-full-title] Indian journal of cancer
  • [ISO-abbreviation] Indian J Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


58. Sukumar MS, Komanapalli CB, Cohen JI: Minimally invasive management of the mediastinal parathyroid adenoma. Laryngoscope; 2006 Mar;116(3):482-7
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Minimally invasive management of the mediastinal parathyroid adenoma.
  • INTRODUCTION/METHODS: Traditional surgical management of mediastinal parathyroid adenomas has required mediastinal exploration via sternotomy or thoracotomy.
  • The availability of sternal retractor systems, the rapid parathyroid hormone (PTH) assay for intraoperative confirmation of cure, recurrent laryngeal nerve monitoring technique and video-assisted thoracic surgery (VATS) instrumentation have made this possible.
  • CONCLUSION: Transcervical approaches for resection of anterior mediastinal parathyroid adenomas are possible with the use of the Rultract Skyhook Retractor without the need for sternotomy.
  • [MeSH-major] Adenoma / surgery. Mediastinal Neoplasms / surgery. Parathyroid Neoplasms / surgery
  • [MeSH-minor] Humans. Minimally Invasive Surgical Procedures. Parathyroid Hormone / blood. Radiopharmaceuticals. Technetium Tc 99m Sestamibi. Thoracic Surgery, Video-Assisted / methods. Tomography, X-Ray Computed. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16540913.001).
  • [ISSN] 0023-852X
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Parathyroid Hormone; 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


59. Caliumi C, Cotesta D, Petramala L, Lorio M, Salvati M, Filetti S, De Toma G, D'Erasmo E, Letizia C: An unusual association of cerebral meningioma, parathyroid adenoma and thyroid papillary carcinoma. Tumori; 2006 Mar-Apr;92(2):178-80
MedlinePlus Health Information. consumer health - Thyroid Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An unusual association of cerebral meningioma, parathyroid adenoma and thyroid papillary carcinoma.
  • The case of a 50-year-old woman with cerebral meningioma and concomitant parathyroid adenoma and papillary thyroid carcinoma is presented.
  • Even though the patient's clinical condition was good, a calcium-phosphorus metabolism test confirmed high plasma levels of ionized calcium and parathyroid hormone.
  • Thyroid and parathyroid ultrasonography revealed multinodular goiter and a parathyroid lesion confirmed by 99mTc-TCO4 / 99mTc-MIBI scintigraphy.
  • Histological examination revealed a parathyroid adenoma and a small papillary carcinoma of 0.4 cm in the right thyroid lobe.
  • As far as we know, this patient is the third case of meningioma associated with parathyroid adenoma and papillary thyroid carcinoma described in the literature.
  • [MeSH-major] Adenoma / diagnosis. Brain Neoplasms / diagnosis. Carcinoma, Papillary / diagnosis. Meningioma / diagnosis. Neoplasms, Multiple Primary / diagnosis. Parathyroid Neoplasms / diagnosis. Thyroid Neoplasms / diagnosis


60. Ogawa T, Tsuji E, Kanauchi H, Yamada K, Mimura Y, Kaminishi M: Excision of postesophageal parathyroid adenoma in posterior mediastinum with intraoperative 99mTechnetium sestamibi scanning. Ann Thorac Surg; 2007 Nov;84(5):1754-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Excision of postesophageal parathyroid adenoma in posterior mediastinum with intraoperative 99mTechnetium sestamibi scanning.
  • Although approximately 25% of parathyroid tumors in patients with primary hyperparathyroidism are located in the mediastinum, nearly all these tumors can be removed through cervical exploration.
  • The mediastinal tumors are usually located in the inferior parathyroid gland, and the ectopic mediastinal tumors derived from the superior glands are extremely rare.
  • We present a case of retroesophageal mediastinal parathyroid adenoma that developed in the left superior parathyroid gland.
  • [MeSH-major] Adenoma / surgery. Choristoma / surgery. Mediastinal Neoplasms / surgery. Parathyroid Neoplasms / surgery. Technetium Tc 99m Sestamibi

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17954108.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


61. Lee LS, Canter RJ, Fraker DL: Intraoperative jugular venous sampling AIDS detection of an undescended parathyroid adenoma. World J Surg; 2006 Apr;30(4):620-3
Genetic Alliance. consumer health - AIDS-HIV.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intraoperative jugular venous sampling AIDS detection of an undescended parathyroid adenoma.
  • INTRODUCTION: A missed parathyroid adenoma is an important cause of persistent or recurrent primary hyperparathyroidism.
  • Despite the widespread use of preoperative localizing tests and the advent of the rapid intact blood parathyroid hormone assay (iPTH), difficult operative cases are encountered when abnormal parathyroid glands cannot be identified.
  • METHODS: Over a 5-year period, 466 neck explorations were performed for primary hyperparathyroidism.
  • This retrospective report describes the use of intraoperative jugular venous sampling to locate and remove successfully undescended parathyroid adenomas in three patients.
  • RESULTS: Intraoperative jugular venous sampling for iPTH analysis was performed when a thorough neck exploration in combination with peripheral iPTH failed to reveal a source of hyperparathyroidism in patients with biochemically confirmed hyperparathyroidism.
  • In all patients, a two- to fourfold iPTH gradient was observed between the affected and unaffected sides, and an undescended adenoma was located near the carotid bifurcation.
  • CONCLUSIONS: Intraoperative jugular venous sampling with iPTH analysis may be a useful technique for successfully detecting an undescended adenoma when other, more routine measures have failed.
  • [MeSH-major] Adenoma / surgery. Hyperparathyroidism / surgery. Monitoring, Intraoperative / methods. Parathyroid Hormone / blood. Parathyroid Neoplasms / surgery. Parathyroidectomy / methods
  • [MeSH-minor] Humans. Jugular Veins. Parathyroid Glands / abnormalities. Retrospective Studies. Sensitivity and Specificity. Tomography, Emission-Computed, Single-Photon

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16555025.001).
  • [ISSN] 0364-2313
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Parathyroid Hormone
  •  go-up   go-down


62. Kim MK, Kim GS, Kim SY, Baek KH, Kang MI, Lee KW, Sohn HS, Park WC, Song KH: F-18 FDG-avid intrathyroidal parathyroid adenoma mimicking follicular neoplasm. Clin Nucl Med; 2009 Mar;34(3):178-9
MedlinePlus Health Information. consumer health - Thyroid Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] F-18 FDG-avid intrathyroidal parathyroid adenoma mimicking follicular neoplasm.
  • A 64-year-old woman was biochemically diagnosed with hyperparathyroidism.
  • Technetium-99m sestamibi parathyroid scan demonstrated persistent uptake in the left lower pole of the thyroid.
  • The intact PTH level in the cystic fluid was much higher than the serum intact PTH level, suggesting an intrathyroidal parathyroid adenoma.
  • Left lobectomy revealed an intrathyroidal parathyroid adenoma in the left thyroid lobe.
  • [MeSH-major] Adenoma / radionuclide imaging. Fluorodeoxyglucose F18. Thyroid Neoplasms / radionuclide imaging
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Hyperparathyroidism / metabolism. Hyperparathyroidism / pathology. Hyperparathyroidism / radionuclide imaging. Middle Aged. Positron-Emission Tomography

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19352286.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
  •  go-up   go-down


63. Sagan D, Goździuk K: Surgical treatment of mediastinal parathyroid adenoma: rationale for intraoperative parathyroid hormone monitoring. Ann Thorac Surg; 2010 Jun;89(6):1750-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical treatment of mediastinal parathyroid adenoma: rationale for intraoperative parathyroid hormone monitoring.
  • However, when the parathyroid adenoma is located deep in the mediastinum, the surgeon often encounters difficulties to localize and completely remove all hyperfunctioning parathyroid tissues.
  • Thus, we hypothesized that patients with mediastinal adenoma differ substantially from cervical cases and require a specific strategy.
  • The aim of this study was to evaluate the efficacy of intraoperative serum parathyroid hormone monitoring (ioPTH) used to guide completeness of targeted mediastinal parathyroidectomy.
  • METHODS: In a 10-year period, 33 patients underwent targeted mediastinal parathyroidectomy with ioPTH for primary sporadic hyperparathyroidism.
  • RESULTS: In 26 patients the adenoma was correctly identified and removed at targeted mediastinal parathyroidectomy.
  • CONCLUSIONS: Mediastinal parathyroid adenoma represents a distinct subset of primary hyperparathyroidism and requires a specific diagnostic and therapeutic approach.
  • [MeSH-major] Adenoma / blood. Adenoma / surgery. Monitoring, Intraoperative. Parathyroid Hormone / blood. Parathyroid Neoplasms / blood. Parathyroid Neoplasms / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20494022.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Parathyroid Hormone
  •  go-up   go-down


64. Chaychi L, Chaidarun S, Golding A, Kinlaw WB, Memoli V, Siegel A: Unusual recurrence of hypercalcemia due to concurrent parathyroid adenoma and parathyroid sarcoidosis with lymph node involvement. Endocr Pract; 2010 May-Jun;16(3):463-7
MedlinePlus Health Information. consumer health - Sarcoidosis.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unusual recurrence of hypercalcemia due to concurrent parathyroid adenoma and parathyroid sarcoidosis with lymph node involvement.
  • OBJECTIVE: To describe a patient presenting with the rare findings of synchronous parathyroid adenoma and parathyroid sarcoidosis.
  • RESULTS: A 67-year-old man had the following initial blood test results: calcium, 11.1 mg/dL (reference range, 8.5-10.6 mg/dL); albumin 4.0 g/dL (reference range, 3.2- 5.2 g/dL); intact parathyroid hormone, 166 pg/mL (reference range, 10-69 pg/mL); creatinine, 1.9 mg/dL; 25-hydroxyvitamin D, 15 ng/mL (reference range, 30-80 ng/mL); and 1,25-dihydroxyvitamin D, 44 pg/mL (reference range, 16-72 pg/mL).
  • Pathologic examination of the resected gland confirmed the diagnosis of parathyroid adenoma, and subsequent review disclosed the presence of noncaseating granulomas within the adenoma.
  • CONCLUSIONS: Sarcoidosis with parathyroid involvement causing severe hypercalcemia is unique to this case.
  • Recurrent hypercalcemia after successful resection of a parathyroid adenoma may require consideration of potential causes other than the initial diagnosis.
  • [MeSH-major] Hypercalcemia / diagnosis. Lymph Nodes / pathology. Parathyroid Diseases / diagnosis. Parathyroid Neoplasms / diagnosis. Sarcoidosis / diagnosis

  • Genetic Alliance. consumer health - Sarcoidosis.
  • MedlinePlus Health Information. consumer health - Parathyroid Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20061287.001).
  • [ISSN] 1934-2403
  • [Journal-full-title] Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
  • [ISO-abbreviation] Endocr Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


65. Akin H, Gunluoglu Z, Kara V, Melek H, Dincer I: Mediastinal ectopic parathyroid adenoma: report of two cases successfully treated by VATS approach. Thorac Cardiovasc Surg; 2008 Feb;56(1):60-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mediastinal ectopic parathyroid adenoma: report of two cases successfully treated by VATS approach.
  • Ectopic parathyroid adenomas are the cause of approximately one in four cases of primary hyperparathyroidism (pHPT).
  • Most ectopic parathyroid adenomas are located adjacent to the upper thymus gland and can be resected with a collar incision.
  • In rare cases, however, adenomas located in the chest require a transsternalor transthoracic approach.
  • We present two cases with primary hyperparathyroidism due to mediastinal ectopic parathyroid adenoma that were successfully treated by VATS approach.
  • [MeSH-major] Mediastinal Neoplasms / surgery. Parathyroid Neoplasms / surgery. Thoracic Surgery, Video-Assisted

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18200473.001).
  • [ISSN] 0171-6425
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


66. Karvounaris DC, Symeonidis N, Triantafyllou A, Flaris N, Sakadamis A: Ectopic parathyroid adenoma located inside the hypoglossal nerve. Head Neck; 2010 Sep;32(9):1273-6
MedlinePlus Health Information. consumer health - Diagnostic Imaging.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ectopic parathyroid adenoma located inside the hypoglossal nerve.
  • BACKGROUND: Intraneural parathyroid adenomas are extremely rare, with only 9 cases of intravagal adenomas reported.
  • We report the first case of an ectopic parathyroid adenoma located within the hypoglossal nerve.
  • Preoperative investigation with neck ultrasound and MRI did not provide a definitive diagnosis, whereas sestamibi scan showed slightly increased radiotracer accumulation in the same area.
  • Histopathology confirmed the presence of a parathyroid adenoma inside the trunk of a nerve.
  • CONCLUSION: This unique case emphasizes the variability of parathyroid anatomy and the difficulties faced by the surgeon when treating this disease process.
  • [MeSH-major] Adenoma / diagnosis. Choristoma / diagnosis. Diagnostic Imaging / methods. Hypoglossal Nerve / pathology. Parathyroid Glands. Parathyroid Neoplasms / diagnosis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19691113.001).
  • [ISSN] 1097-0347
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


67. Johnson NA, Yip L, Tublin ME: Cystic parathyroid adenoma: sonographic features and correlation with 99mTc-sestamibi SPECT findings. AJR Am J Roentgenol; 2010 Dec;195(6):1385-90
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cystic parathyroid adenoma: sonographic features and correlation with 99mTc-sestamibi SPECT findings.
  • OBJECTIVE: The purpose of this study was to describe the typical ultrasound features of cystic parathyroid adenoma.
  • MATERIALS AND METHODS: A review of a surgical database and electronic medical records from 2006 to 2009 identified the cases of 15 patients who underwent preoperative cervical sonography for primary hyperparathyroidism with subsequent resection of pathologically proven parathyroid adenoma with predominantly cystic components.
  • Technetium-99m-sestamibi SPECT findings, surgical and pathologic reports, and the results of parathyroid hormone assay of the cyst fluid also were reviewed.
  • RESULTS: Most of the cystic adenomas (14/15, 93%) were deep or inferolateral to the adjacent thyroid.
  • An echogenic border separating the adenoma from the overlying thyroid was identified in 9 of 15 patients (60%).
  • Six of 14 patients underwent preoperative or intraoperative sampling of cyst fluid, and the assay showed the parathyroid hormone levels ranged from 1,198 to greater than 5,000 pg/mL.
  • Fourteen of 15 patients underwent preoperative sestamibi SPECT, and the adenoma was definitively localized in four patients (29%).
  • CONCLUSION: Awareness of typical sonographic features (location, color Doppler vascularity) may aid radiologists in preoperative localization of parathyroid adenomas, even when cystic degeneration occurs.
  • In cases in which imaging or clinical features are equivocal, the results of cyst fluid sampling and parathyroid hormone assay are confirmatory.
  • [MeSH-major] Adenoma / radionuclide imaging. Adenoma / ultrasonography. Parathyroid Neoplasms / radionuclide imaging. Parathyroid Neoplasms / ultrasonography. Tomography, Emission-Computed, Single-Photon. Ultrasonography, Doppler, Color
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Hyperparathyroidism, Primary / etiology. Male. Middle Aged. Radiopharmaceuticals. Retrospective Studies. Technetium Tc 99m Sestamibi

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21098199.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


68. Steward DL, Danielson GP, Afman CE, Welge JA: Parathyroid adenoma localization: surgeon-performed ultrasound versus sestamibi. Laryngoscope; 2006 Aug;116(8):1380-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Parathyroid adenoma localization: surgeon-performed ultrasound versus sestamibi.
  • OBJECTIVES: Compare surgeon-performed ultrasound versus sestamibi for preoperative parathyroid adenoma localization.
  • Primary outcome is sensitivity for adenoma localization to correct quadrant (right vs. left, superior vs. inferior).
  • [MeSH-major] Adenoma / diagnosis. Parathyroid Neoplasms / diagnosis. Technetium Tc 99m Sestamibi
  • [MeSH-minor] Humans. Hypercalcemia / diagnosis. Hyperparathyroidism / diagnosis. Parathyroidectomy. Predictive Value of Tests. Sensitivity and Specificity

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Laryngoscope. 2007 Feb;117(2):382; author reply 382-3 [17277637.001]
  • (PMID = 16885740.001).
  • [ISSN] 0023-852X
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


69. Taguchi M, Endo S, Hasegawa T, Sato Y, Sohara Y: Thoracoscopic findings of a small posterior mediastinal parathyroid adenoma. Asian Cardiovasc Thorac Ann; 2006 Oct;14(5):e86-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Thoracoscopic findings of a small posterior mediastinal parathyroid adenoma.
  • We report herein the rare case of a posterior mediastinal parathyroid adenoma 8 mm in diameter, that was identified by both 99m-technetium-methoxyisobutylisonitrile scintigraphy (Tc-MIBI) and high-resolution chest computed tomography (HRCT).
  • Thoracoscopy clearly showed a mediastinal parathyroid adenoma which was successfully removed.
  • [MeSH-major] Adenoma / surgery. Mediastinal Neoplasms / surgery. Parathyroid Neoplasms / surgery. Thoracic Surgery, Video-Assisted

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17005872.001).
  • [ISSN] 1816-5370
  • [Journal-full-title] Asian cardiovascular & thoracic annals
  • [ISO-abbreviation] Asian Cardiovasc Thorac Ann
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  •  go-up   go-down


70. Durán CE, Torregrosa JV, Canalejo A, Almadén Y, Campistol JM, Rodríguez Portillo M: [In vitro dynamics of parathyroid hormone secretion regulated by calcium and effects on the cell cycle: parathyroid hyperplasia versus adenoma]. Nefrologia; 2010;30(4):413-9
Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [In vitro dynamics of parathyroid hormone secretion regulated by calcium and effects on the cell cycle: parathyroid hyperplasia versus adenoma].
  • [Transliterated title] Dinámica in vitro de la secreción de hormona paratiroidea regulada por calcio y efecto sobre el ciclo celular: adenoma frente a hiperplasia paratiroidea.
  • AIM: To compare the dynamics of calcium-regulated PTH secretion in vitro from adenomatous versus hyperplastic glands and to investigate the relationship between the parathyroid cell cycle and the calcium-regulated PTH secretion in these glands.
  • MATERIALS AND METHODS: A total of 31 parathyroid glands (8 adenomatous and 23 hyperplastic) from 8 patients with primary hyperparathyroidism and 7 with secondary hyperparathyroidism respectively were studied.
  • For the evaluation of calcium-regulated PTH secretion, small parathyroid pieces of 1 mm were sequentially transferred to wells with varying Ca concentrations: 0.4, 0.6, 0.8, 1, 1.25 and 1.35 or 1.5 mM.
  • For the parathyroid cell cycle studies, parathyroid cells were isolated without the use of enzymes and cell cycle was analyzed using the method described by Vindelov.
  • RESULTS: In parathyroid tissues from hyperplastic glands, the increase in extracellular calcium produced a decrease in PTH secretion which was apparent with a calcium level as low as 0.8 mM and the maximal inhibition of PTH secretion was obtained with a calcium of 1.25 mM, by the contrary, adenomatous glands required a calcium of 1.2 mM to produce a minimal decrease in PTH secretion.
  • In hyperplastic parathyroid glands but not in parathyroid adenomas there was a significant correlation between the percentage of cells in G0/G1 phase with the set point (r = 0.914; P < 0.005) and the basal serum Ca (r = 0.862; P < 0.02).
  • CONCLUSIONS: The control of the extracellular calcium-PTH release in vitro is less sensitive in parathyroid adenomas than hyperplasic parathyroid glands.
  • In parathyroid hyperplasia the cell proliferation may be regulated by the extracellular calcium concentration (higher calcemia less proliferation).
  • [MeSH-major] Adenoma / secretion. Calcium / physiology. Cell Cycle / physiology. Parathyroid Glands / pathology. Parathyroid Glands / secretion. Parathyroid Hormone / secretion. Parathyroid Neoplasms / secretion

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20651882.001).
  • [ISSN] 0211-6995
  • [Journal-full-title] Nefrología : publicación oficial de la Sociedad Española Nefrologia
  • [ISO-abbreviation] Nefrologia
  • [Language] spa
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Parathyroid Hormone; SY7Q814VUP / Calcium
  •  go-up   go-down


71. Yang ZQ, Zhu LW, Wang PZ: [Diagnosis and surgical treatment of 48 cases of parathyroid adenoma and parathyroid carcinoma]. Zhonghua Zhong Liu Za Zhi; 2006 Aug;28(8):625-7
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Diagnosis and surgical treatment of 48 cases of parathyroid adenoma and parathyroid carcinoma].
  • OBJECTIVE: To summarize the experience in diagnosis and surgical treatment of parathyroid adenoma and carcinoma (PTA and PTC) in our department.
  • Among the 48 cases, 46 cases were of parathyroid adenoma and 2 cases of parathyroid carcinoma.
  • Serum calcium and PTH assays are both reliable methods for the diagnosis of PTA and PTC.
  • A combination of ultrasonography and 99mTc-MIBI scintigraphy is sufficient for locating adenomas.
  • Accompanied by intraoperative pathological examination, unilateral neck exploration is an acceptable approach for patients with definitely preoperative confirmed adenoma localization.
  • [MeSH-major] Adenoma / diagnosis. Adenoma / surgery. Parathyroid Neoplasms / diagnosis. Parathyroid Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Calcium / blood. Echocardiography, Doppler, Color. Female. Follow-Up Studies. Humans. Hypocalcemia / etiology. Male. Middle Aged. Neck Dissection. Parathyroid Hormone / blood. Parathyroidectomy / adverse effects. Parathyroidectomy / methods. Retrospective Studies. Technetium Tc 99m Sestamibi

  • Genetic Alliance. consumer health - Parathyroid carcinoma.
  • Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17236561.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Parathyroid Hormone; 971Z4W1S09 / Technetium Tc 99m Sestamibi; SY7Q814VUP / Calcium
  •  go-up   go-down


72. Berland T, Smith SL, Huguet KL: Occult fifth gland intrathyroid parathyroid adenoma identified by gamma probe. Am Surg; 2005 Mar;71(3):264-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Occult fifth gland intrathyroid parathyroid adenoma identified by gamma probe.
  • The gamma probe was instrumental in guiding us to the adenoma in a fifth gland that was not visible and was localized to the parenchyma of the left lobe of the thyroid gland.
  • Many surgeons do not advocate use of the gamma probe in minimally invasive parathyroidectomy and rely solely on focused exploration on the basis of a preoperative sestamibi scan and intraoperative rapid parathyroid hormone assays.
  • This case, however, illustrates the utility of the gamma probe in parathyroid adenoma localization.
  • [MeSH-major] Adenoma / radionuclide imaging. Adenoma / surgery. Parathyroid Glands / abnormalities. Parathyroid Neoplasms / radionuclide imaging. Technetium Tc 99m Sestamibi
  • [MeSH-minor] Female. Follow-Up Studies. Gamma Cameras. Humans. Hyperparathyroidism / diagnosis. Hyperparathyroidism / etiology. Middle Aged. Minimally Invasive Surgical Procedures / instrumentation. Parathyroidectomy / methods. Risk Assessment. Sensitivity and Specificity

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15869146.001).
  • [ISSN] 0003-1348
  • [Journal-full-title] The American surgeon
  • [ISO-abbreviation] Am Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


73. Majithia A, Stearns MP: Methylene blue toxicity following infusion to localize parathyroid adenoma. J Laryngol Otol; 2006 Feb;120(2):138-40
Hazardous Substances Data Bank. METHYLENE BLUE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Methylene blue toxicity following infusion to localize parathyroid adenoma.
  • The parathyroid glands are small, inconspicuous, and variable in number, colour and position.
  • Intravenous infusion of methylene blue at a dose of 7.5 mg/kg is commonly used to aid visualization of the parathyroid glands intra-operatively.
  • Methylene blue is generally considered benign, and there are only two cases published in the literature reporting toxicity following intravenous infusion--such toxicity is a diagnosis of exclusion.
  • We report a case of methylene blue toxicity resulting in expressive aphasia, confusion and disinhibition following infusion for parathyroid adenoma localization.
  • This has not affected our success rate for identification of parathyroid glands.
  • [MeSH-major] Adenoma / surgery. Coloring Agents / adverse effects. Methylene Blue / adverse effects. Parathyroid Neoplasms / surgery. Postoperative Complications / chemically induced

  • MedlinePlus Health Information. consumer health - After Surgery.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] J Laryngol Otol. 2006 Aug;120(8):708; author reply 708-9 [16884551.001]
  • (PMID = 16359577.001).
  • [ISSN] 0022-2151
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Coloring Agents; T42P99266K / Methylene Blue
  •  go-up   go-down


74. Abikhzer G, Levental M, Rush C: High resolution MRI in the detection of an intrathymic parathyroid adenoma. Br J Radiol; 2006 Sep;79(945):e78-80
MedlinePlus Health Information. consumer health - MRI Scans.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] High resolution MRI in the detection of an intrathymic parathyroid adenoma.
  • The most common cause of primary hyperparathyroidism is parathyroid adenoma.
  • Multiple imaging techniques have been utilized in the detection of ectopic adenoma and are discussed.
  • We report on a case of an intrathymic parathyroid adenoma that was detected through the novel use of a breast coil in performing a high resolution MRI.
  • [MeSH-major] Adenoma / diagnosis. Magnetic Resonance Imaging / methods. Parathyroid Neoplasms / diagnosis
  • [MeSH-minor] Adult. Female. Humans. Hyperparathyroidism, Primary / etiology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16940365.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  •  go-up   go-down


75. Khan MS, Khan S, Vereb M, Al-Nahhas AM, Dina R, Lynn J, Fleming W: Ectopic parathyroid adenoma with Tc-99m MIBI washout: role of SPECT. Clin Nucl Med; 2006 Nov;31(11):713-5
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ectopic parathyroid adenoma with Tc-99m MIBI washout: role of SPECT.
  • The authors present a case of a 71-year-old woman with clinical and biochemical features of primary hyperparathyroidism and a history of right pneumonectomy.
  • However, unlike most adenomas, this demonstrated washout similar to the thyroid at 90 minutes and 3 hours.
  • After surgery, histology confirmed the diagnosis of a parathyroid adenoma.
  • [MeSH-major] Adenoma / radionuclide imaging. Choristoma / radionuclide imaging. Parathyroid Glands. Parathyroid Neoplasms / radionuclide imaging. Technetium Tc 99m Sestamibi

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17053393.001).
  • [ISSN] 0363-9762
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


76. Aliyev A, Kabasakal L, Simsek O, Paksoy M, Halac M, Uslu I: Ectopic parathyroid adenoma localized with MIBI scintigraphy and excised with guide of macroaggregated human serum albumin injection. Clin Nucl Med; 2010 Mar;35(3):151-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ectopic parathyroid adenoma localized with MIBI scintigraphy and excised with guide of macroaggregated human serum albumin injection.
  • Primary hyperparathyroidism is caused by an excessive amount of parathyroid hormone secreted by one or more enlarged parathyroid glands.
  • Most commonly primary hyperparathyroidism is caused by a parathyroid adenoma.
  • Ectopic parathyroid adenomas are rare, but they can complicate the surgical treatment and have an increased morbidity and poorer success rate.
  • Thus, preoperative imaging is particularly valuable in this group of patients with hyperparathyroidism.
  • Preoperative imaging has opened up a new era of minimally invasive parathyroid surgery procedures.
  • In this report, we investigated the usefulness of the radio-guided occult lesion localization technique in the identification of ectopic parathyroid adenomas.
  • Tc-99m methoxy-isobutyl-isonitrile scintigraphy identified an ectopic parathyroid adenoma.
  • Careful dissection was then carried out and an enlarged ectopic parathyroid gland was removed.
  • In conclusion, the preoperative imaging of an ectopic parathyroid adenoma and the excision of this tissue with radioguided occult lesion localization technique can open up a new era of minimally invasive parathyroid surgery.
  • [MeSH-major] Choristoma / radionuclide imaging. Choristoma / surgery. Parathyroid Neoplasms / radionuclide imaging. Parathyroid Neoplasms / surgery. Serum Albumin / administration & dosage. Technetium Tc 99m Sestamibi

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20173443.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Serum Albumin; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


77. Ahmad S, Jielani AA, Khan K, Fatima T, Zia N, ud Duha M, Samad A, Memon K: Dual phase MIBI scintigraphy in diagnosis of parathyroid adenoma followed by ultrasound guided percutaneous alcoholic ablation. J Ayub Med Coll Abbottabad; 2008 Jul-Sep;20(3):149-51
Hazardous Substances Data Bank. ETHANOL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dual phase MIBI scintigraphy in diagnosis of parathyroid adenoma followed by ultrasound guided percutaneous alcoholic ablation.
  • Primary Hyperparathyroidism (HPT) is an inappropriate hyper secretion of parathyroid hormone (PTH).
  • Primary HPT is caused by parathyroid adenoma in 80-85% of patients.
  • Ultrasonography is widely used in suspected cases for localization of parathyroid adenoma.
  • There is considerable intra-observer variation and it is difficult for ultrasound alone to differentiate parathyroid lesion form that of thyroid.
  • Dual phase Tc-99m MIBI scinitigraphy for detection of parathyroid adenomas has sensitivity and specificity values ranging from 82% to 100% and from 89% to 100%, respectively.
  • Percutaneous ethanol injection for parathyroid glands can be applied effectively in selected cases when surgery is unadvisable either for technical reasons (e.g., recurrence ofhyperplastic glands in the neck after subtotal surgery or intrathyroideal parathyroid tumors or the poor clinical state of the patient.
  • [MeSH-major] Adenoma / radionuclide imaging. Adenoma / therapy. Catheter Ablation / methods. Ethanol / therapeutic use. Parathyroid Neoplasms / radionuclide imaging. Parathyroid Neoplasms / therapy

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19610543.001).
  • [ISSN] 1025-9589
  • [Journal-full-title] Journal of Ayub Medical College, Abbottabad : JAMC
  • [ISO-abbreviation] J Ayub Med Coll Abbottabad
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 3K9958V90M / Ethanol; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


78. Kirov G, Boneva Zh, Protich M, Koleva N, Paskalev V, Iovchevski P, Lozev I, Liutskanov V: [Intrathyroidal parathyroid adenoma and ectopic parathyroid gland in thyroid nodule - report of two cases]. Khirurgiia (Sofiia); 2007;(3):64-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Intrathyroidal parathyroid adenoma and ectopic parathyroid gland in thyroid nodule - report of two cases].
  • Ectopic locations of parathyroid adenomas are a rare condition and can cause difficulty in their diagnosis and surgical treatment.
  • We report two cases of intrathyroid parathyroid lesions.
  • In the first patient, preoperative localization studies suggested the possibility of a parathyroid adenoma outside the thyroid gland.
  • When a pathological gland is not found during surgery for primary hyperparathyroidism, an ectopic parathyroid gland was found in the thyroid tissue.
  • In the second patient, in an existing thyroid nodule was found an ectopic normal parathyroid gland postoperatively.
  • [MeSH-major] Choristoma. Goiter, Nodular. Parathyroid Glands. Parathyroid Neoplasms

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18437114.001).
  • [ISSN] 0450-2167
  • [Journal-full-title] Khirurgii︠a︡
  • [ISO-abbreviation] Khirurgiia (Sofiia)
  • [Language] bul
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Bulgaria
  •  go-up   go-down


79. Balasanthiran A, Sandler B, Amonoo-Kuofi K, Swamy R, Kaniyur S, Kaplan F: Sarcoid granulomas in the parathyroid gland - a case of dual pathology: hypercalcaemia due to a parathyroid adenoma and coexistent sarcoidosis with granulomas located within the parathyroid adenoma and thyroid gland. Endocr J; 2010;57(7):603-7
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sarcoid granulomas in the parathyroid gland - a case of dual pathology: hypercalcaemia due to a parathyroid adenoma and coexistent sarcoidosis with granulomas located within the parathyroid adenoma and thyroid gland.
  • We present a highly unusual and interesting case of coexistent hyperparathyroidism and sarcoidosis leading to hypercalcaemia.
  • Parathyroid imaging was then requested and an adenoma was identified.
  • Surprisingly, surgery revealed the coexistence of a parathyroid adenoma with the unexpected finding of sarcoid granulomas within the parathyroid and thyroid glands.
  • [MeSH-major] Adenoma / complications. Granuloma / complications. Hypercalcemia / etiology. Parathyroid Diseases / complications. Parathyroid Neoplasms / complications. Sarcoidosis / complications. Thyroid Neoplasms / complications
  • [MeSH-minor] Aged. Female. Humans. Neoplasms, Multiple Primary / complications. Neoplasms, Multiple Primary / surgery. Parathyroid Glands / pathology. Parathyroid Glands / surgery. Parathyroidectomy. Thyroid Gland / pathology


80. Powell AC, Alexander HR, Chang R, Marx SJ, Skarulis M, Pingpank JF, Bartlett DL, Hughes M, Weinstein LS, Simonds WF, Collins MF, Shawker T, Chen CC, Reynolds J, Cochran C, Steinberg SM, Libutti SK: Reoperation for parathyroid adenoma: a contemporary experience. Surgery; 2009 Dec;146(6):1144-55
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Reoperation for parathyroid adenoma: a contemporary experience.
  • BACKGROUND: We reviewed reoperations for persistent or recurrent sporadic parathyroid adenoma to evaluate and compare our current results and outcomes to our previous experience.
  • METHODS: From 1996 to 2008, 237 patients with persistent or recurrent hyperparathyroidism after failed operation underwent reoperation.
  • RESULTS: A missed adenoma was suspected pre-operatively in 163 patients.
  • Adenomas were in entopic locations in 32%; the most frequent ectopic location was the thymus (20%).
  • [MeSH-major] Adenoma / surgery. Parathyroid Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Hypercapnia / etiology. Hypercapnia / surgery. Hyperparathyroidism / surgery. Male. Middle Aged. Neoplasm Recurrence, Local / complications. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / surgery. Parathyroid Hormone / blood. Postoperative Complications / etiology. Recurrent Laryngeal Nerve Injuries. Reoperation. Retrospective Studies. Treatment Outcome. Young Adult

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Arch Surg. 1996 Aug;131(8):861-7; discussion 867-9 [8712911.001]
  • [Cites] J Nucl Med. 1995 Dec;36(12):2186-91 [8523102.001]
  • [Cites] World J Surg. 2007 Nov;31(11):2075-80 [17768656.001]
  • [Cites] J Am Coll Surg. 2008 Aug;207(2):246-9 [18656054.001]
  • [Cites] Am J Surg. 2008 Dec;196(6):937-42; discussion 942-3 [19095113.001]
  • [Cites] Ann Surg. 1996 Sep;224(3):308-20; discussion 320-1 [8813259.001]
  • [Cites] Surgery. 1999 Dec;126(6):1042-8 [10598186.001]
  • [Cites] Surgery. 2000 Dec;128(6):1103-9;discussion 1109-10 [11114649.001]
  • [Cites] Surgery. 2002 Feb;131(2):149-57 [11854692.001]
  • [Cites] Ann Surg. 2002 Nov;236(5):543-51 [12409657.001]
  • [Cites] J Bone Miner Res. 2002 Nov;17 Suppl 2:N133-40 [12412790.001]
  • [Cites] Ann Surg. 1981 Dec;194(6):671-6 [7305478.001]
  • [Cites] Surgery. 1982 Jun;91(6):616-21 [6123156.001]
  • [Cites] Ann Surg. 1985 Jan;201(1):40-4 [2981520.001]
  • [Cites] Surgery. 1987 May;101(5):562-5 [3576448.001]
  • [Cites] Radiology. 1989 Mar;170(3 Pt 2):1003-6 [2644666.001]
  • [Cites] Arch Surg. 1989 Jun;124(6):676-80 [2730318.001]
  • [Cites] World J Surg. 1991 Nov-Dec;15(6):688-92 [1767534.001]
  • [Cites] J Nucl Med. 1992 Oct;33(10):1801-7 [1328564.001]
  • [Cites] Surgery. 1993 Dec;114(6):1004-9; discussion 1009-10 [8256203.001]
  • [Cites] Am J Clin Pathol. 1994 Sep;102(3):365-73 [8085562.001]
  • [Cites] Surgery. 1994 Dec;116(6):959-64; discussion 964-5 [7985103.001]
  • [CommentIn] Surgery. 2009 Dec;146(6):1156-7 [19958943.001]
  • (PMID = 19958942.001).
  • [ISSN] 1532-7361
  • [Journal-full-title] Surgery
  • [ISO-abbreviation] Surgery
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / / Z01 DE000649-13
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Parathyroid Hormone
  • [Other-IDs] NLM/ NIHMS148016; NLM/ PMC3467310
  •  go-up   go-down


81. Power C, Kavanagh D, Hill AD, O'Higgins N, McDermott E: Unusual presentation of a giant parathyroid adenoma: report of a case. Surg Today; 2005;35(3):235-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unusual presentation of a giant parathyroid adenoma: report of a case.
  • Parathyroid adenomas account for most cases of primary hyperparathyroidism (1 degrees HPT).
  • Parathyroid adenomas rarely attain huge proportions.
  • We report a case of a parathyroid adenoma measuring 8 x 5 x 3.5 cm and weighing 110 g; to our knowledge the greatest mass reported in the literature.
  • Interestingly, despite its huge size it did not cause many of the hypercalcemic symptoms usually associated with larger adenomas, but rather it manifested with symptoms of local pressure, another unusual property of this atypical tumor.
  • [MeSH-major] Adenoma / pathology. Adenoma / surgery. Parathyroid Neoplasms / pathology. Parathyroid Neoplasms / surgery
  • [MeSH-minor] Aged. Aged, 80 and over. Biopsy, Needle. Female. Follow-Up Studies. Humans. Hyperparathyroidism / diagnosis. Hyperparathyroidism / etiology. Immunohistochemistry. Ireland. Neoplasm Staging. Parathyroidectomy / methods. Risk Assessment. Severity of Illness Index. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15772795.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


82. Randhawa PS, Mace AD, Nouraei SA, Stearns MP: Primary hyperparathyroidism: do perioperative biochemical variables correlate with parathyroid adenoma weight or volume? Clin Otolaryngol; 2007 Jun;32(3):179-84
Hazardous Substances Data Bank. CALCIUM, ELEMENTAL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary hyperparathyroidism: do perioperative biochemical variables correlate with parathyroid adenoma weight or volume?
  • OBJECTIVES: To investigate the relationship between clinical variables and biochemical markers of calcium homeostasis and parathyroid adenoma size, in patients undergoing surgery for primary hyperparathyroidism.
  • PARTICIPANTS: Ninety-two patients treated surgically for primary hyperparathyroidism caused by a solitary parathyroid adenoma between 1996 and 2006.
  • MAIN OUTCOME MEASURES: Complete data was obtained for 77 participants including patient demographics, perioperative calcium, parathyroid hormone and phosphate levels, adenoma weight and histological dimensions.
  • Multiple and binary logistic regression analyses were used to investigate the relationship between clinical and biochemical variables and adenoma weight and volume.
  • The mean adenoma weight was 1.71 +/- 1.41 g.
  • No correlation existed between clinical variables and preoperative biochemical markers of calcium homeostasis and adenoma weight or volume.
  • CONCLUSIONS: Biochemical parameters will not accurately predict the size of a parathyroid adenoma.
  • The size of a parathyroid adenoma does not correlate with postoperative calcium levels and is therefore not useful as a predictor of postoperative hypocalcaemia.
  • [MeSH-major] Adenoma / metabolism. Adenoma / pathology. Biomarkers, Tumor / blood. Calcium / blood. Hyperparathyroidism / metabolism. Parathyroid Hormone / blood. Parathyroid Neoplasms / metabolism. Parathyroid Neoplasms / pathology

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17550505.001).
  • [ISSN] 1749-4478
  • [Journal-full-title] Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery
  • [ISO-abbreviation] Clin Otolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Parathyroid Hormone; SY7Q814VUP / Calcium
  •  go-up   go-down


83. Karpinski S, Sardi A: Thoracoscopic resection of a mediastinal intrathymic parathyroid adenoma. Am Surg; 2005 Dec;71(12):1070-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Thoracoscopic resection of a mediastinal intrathymic parathyroid adenoma.
  • Mediastinal parathyroid adenomas and thymomas can be resected via a transcervical approach, median sternotomy, or less invasive surgical option of video-assisted thoracoscopic resection and more recently by way of the da Vinci robot.
  • We present a case of a mediastinal parathyroid adenoma in a 55-year-old female with primary hyperparathyroidism.
  • MRI also confirmed a mediastinal adenoma localized on sestamibi scan.
  • Significant laboratory values were elevated parathyroid hormone (PTH) of 171 pg/mL (normal range = 15 to 65 pg/mL) and calcium of 11.6 mg/dL (normal range = 8.5 to 10.5 mg/dL).
  • To avoid a median sternotomy, we performed thoracoscopic resection of the adenoma via the left chest with the patient in a right lateral decubitus position.
  • Initial intraoperative PTH measurement was 192.9 pg/mL, and after adenoma removal the PTH level fell to 9 pg/mL.
  • The 4 g, 2.4 cm intrathymic parathyroid adenoma had no evidence of malignancy.
  • Thoracoscopic resection of an intrathymic parathyroid adenoma, a safe and less morbid alternative to median sternotomy, is an option when the transcervical approach is not viable.
  • [MeSH-major] Adenoma / diagnosis. Adenoma / surgery. Mediastinum / surgery. Parathyroid Neoplasms / diagnosis. Parathyroid Neoplasms / surgery. Thoracoscopy / methods

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16447483.001).
  • [ISSN] 0003-1348
  • [Journal-full-title] The American surgeon
  • [ISO-abbreviation] Am Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


84. Gurrado A, Marzullo A, Lissidini G, Lippolis A, Rubini D, Lastilla G, Testini M: Substernal oxyphil parathyroid adenoma producing PTHrP with hypercalcemia and normal PTH level. World J Surg Oncol; 2008;6:24
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Substernal oxyphil parathyroid adenoma producing PTHrP with hypercalcemia and normal PTH level.
  • BACKGROUND: Parathyroid adenoma is the most common cause of primary hyperparathyroidism.
  • Preoperative serum calcium and intact-parathyroid hormone levels are the most useful diagnostic parameters that allow differentiating primary hyperparathyroidism from non-parathyroid-dependent hypercalcemia.
  • Parathyroidectomy is the definitive treatment for primary hyperparathyroidism.
  • Approximately 5% of patients who underwent parathyroidectomy present with persistent or recurrent hyperparathyroidism due to ectopic localization of the adenoma.
  • Functioning oxyphil parathyroid adenoma is an uncommon histological form, seldom causing primary hyperparathyroidism.
  • Parathyroid adenoma with hypercalcemia exhibiting normal parathyroid hormone level is rare.
  • In 1987, parathyroid-hormone-related peptide was isolated as a causative factor of humeral hypercalcemia of malignancy.
  • The presence of parathyroid-hormone-related peptide in parathyroid tissue under normal and pathological conditions has been described in the literature; however, its role in causing hyperparathyroidism has not yet been defined.
  • CASE PRESENTATION: We present a case of persistent hypercalcemia with a normal level of intact-parathyroid hormone due to a substernal parathyroid adenoma, treated with radioguided parathyroidectomy.
  • The final histological diagnosis was oxyphil adenoma, positive for parathyroid-hormone-related peptide antigens.
  • CONCLUSION: In clinical practice, this atypical biochemical presentation of primary hyperparathyroidism should be considered in the differential diagnosis of hypercalcemia.
  • The parathyroid-hormone-related peptide should be considered not only in the presence of malignancy.
  • [MeSH-major] Adenoma / complications. Adenoma / diagnosis. Hypercalcemia / etiology. Parathyroid Hormone / blood. Parathyroid Hormone-Related Protein / blood. Parathyroid Neoplasms / complications. Parathyroid Neoplasms / diagnosis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] South Med J. 2001 Mar;94(3):339-41 [11284524.001]
  • [Cites] Histol Histopathol. 2002 Jan;17(1):179-84 [11813867.001]
  • [Cites] World J Surg. 2003 Apr;27(4):481-5 [12658497.001]
  • [Cites] Br J Urol. 1976;48(7):539-48 [1016827.001]
  • [Cites] Am J Pathol. 1978 Sep;92(3):691-711 [686153.001]
  • [Cites] Am J Surg Pathol. 1989 Jun;13(6):500-4 [2729500.001]
  • [Cites] J Clin Endocrinol Metab. 2006 Oct;91(10):3826-9 [16849415.001]
  • [Cites] Am J Med. 1991 Nov;91(5):547-8 [1951417.001]
  • [Cites] Acta Pathol Jpn. 1992 Jan;42(1):35-41 [1557986.001]
  • [Cites] Zentralbl Chir. 2005 Apr;130(2):109-13 [15849652.001]
  • [Cites] Semin Nucl Med. 2006 Jul;36(3):206-11 [16762611.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 2006 Jul;132(7):779-82 [16847189.001]
  • [Cites] J Clin Endocrinol Metab. 1989 Dec;69(6):1240-8 [2573615.001]
  • (PMID = 18291038.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Parathyroid Hormone; 0 / Parathyroid Hormone-Related Protein
  • [Other-IDs] NLM/ PMC2279131
  •  go-up   go-down


85. Imachi H, Murao K, Kontani K, Yokomise H, Miyai Y, Yamamoto Y, Kushida Y, Haba R, Ishida T: Ectopic mediastinal parathyroid adenoma: a cause of acute pancreatitis. Endocrine; 2009 Oct;36(2):194-7
MedlinePlus Health Information. consumer health - Pancreatitis.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ectopic mediastinal parathyroid adenoma: a cause of acute pancreatitis.
  • After the episode of acute pancreatitis subsided, laboratory investigation revealed increased serum calcium (12.0 mg/dl), decreased serum phosphorus (2.7 mg/dl), and increased serum parathyroid hormone (intact) levels (131 pg/ml).
  • A computed tomography (CT) scan of the neck did not reveal any mass lesions in the parathyroid gland.
  • However, (99m)Tc sestamibi scintigraphy revealed that there was one functioning parathyroid gland in the upper mediastinum.
  • Combined (99m)Tc sestamibi scintigraphy and CT scan confirmed the diagnosis of primary hyperparathyroidism in the mediastinum.
  • Microscopic examination revealed the presence of a parathyroid adenoma (1.3 x 0.4 cm(2)) adjacent to the atrophic parathyroid gland in right thymus gland.
  • We report the case of a patient diagnosed with primary hyperparathyroidism due to an ectopic mediastinal parathyroid adenoma.
  • An ectopic mediastinal parathyroid adenoma may manifest as an episode of acute pancreatitis.
  • Preoperative investigation to determine the exact location of an adenoma should include two types of imaging studies, preferably (99m)Tc sestamibi scintigraphy and CT of the neck and chest.
  • [MeSH-major] Adenoma / complications. Choristoma. Mediastinal Diseases / complications. Pancreatitis / etiology. Parathyroid Glands. Parathyroid Neoplasms / complications
  • [MeSH-minor] Adult. Humans. Hyperparathyroidism, Primary / diagnosis. Hyperparathyroidism, Primary / etiology. Male

  • Genetic Alliance. consumer health - Pancreatitis.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19598003.001).
  • [ISSN] 1559-0100
  • [Journal-full-title] Endocrine
  • [ISO-abbreviation] Endocrine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


86. Yeşilkaya E, Cinaz P, Bideci A, Camurdan O, Demirel F, Demircan S: Hungry bone syndrome after parathyroidectomy caused by an ectopic parathyroid adenoma. J Bone Miner Metab; 2009;27(1):101-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hungry bone syndrome after parathyroidectomy caused by an ectopic parathyroid adenoma.
  • Hungry bone syndrome (HBS), i.e., persistent hypocalcemia and hypophosphatemia as a result of extensive remineralization, is rarely encountered in children after parathyroid surgery.
  • Herein, we report a 12-year-old girl who was diagnosed to have an ectopic parathyroid adenoma, and HBS was observed in the postsurgical follow-up.
  • The diagnosis and the risk factors are discussed in the light of the literature.
  • [MeSH-major] Hypocalcemia / etiology. Hypophosphatemia / etiology. Parathyroid Neoplasms / complications. Parathyroid Neoplasms / surgery. Parathyroidectomy / adverse effects
  • [MeSH-minor] Child. Female. Humans. Syndrome. Thymus Gland / pathology. Thymus Gland / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19057842.001).
  • [ISSN] 0914-8779
  • [Journal-full-title] Journal of bone and mineral metabolism
  • [ISO-abbreviation] J. Bone Miner. Metab.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


87. Atabek ME, Pirgon O, Sert A, Esen HH: Extensive brown tumors caused by parathyroid adenoma in an adolescent patient. Eur J Pediatr; 2008 Jan;167(1):117-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extensive brown tumors caused by parathyroid adenoma in an adolescent patient.
  • Primary hyperparathyroidism is a rare endocrine disease in children and young adults.
  • The early detection and treatment of primary hyperparathyroidism led to a marked decrease in classical bone and renal manifestations of the disease.
  • Moreover, the skeletal involvement in primary hyperparathyroidism secondary to parathyroid adenoma is extremely rare.
  • We report on an adolescent girl with multiple brown tumors and a history of recurrent fractures as the manifestation of primary hyperparathyroidism associated with a parathyroid adenoma.
  • The patient's clinical presentation mimicked parathyroid carcinoma.
  • She had a large tumor associated with marked elevation in the parathyroid hormone and serum calcium levels.
  • Skeletal manifestations were also atypical for benign primary hyperparathyroidism, with widespread brown tumors in the patient.
  • [MeSH-major] Adenoma / complications. Hyperparathyroidism, Primary / etiology. Osteitis Fibrosa Cystica / etiology. Parathyroid Neoplasms / complications
  • [MeSH-minor] Adolescent. Female. Humans. Parathyroid Hormone / biosynthesis. Parathyroid Hormone / blood

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17273830.001).
  • [ISSN] 1432-1076
  • [Journal-full-title] European journal of pediatrics
  • [ISO-abbreviation] Eur. J. Pediatr.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Parathyroid Hormone
  •  go-up   go-down


88. Libánský P, Astl J, Adámek S, Nanka O, Pafko P, Spacková J, Foltán R, Sedý J: Ectopic parathyroid adenoma in child. Prague Med Rep; 2008;109(2-3):200-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ectopic parathyroid adenoma in child.
  • Ultrasonography and MIBI scintigraphy showed a structure near the lower pole of thyroid gland.
  • The structure macroscopically appeared as adenoma, histologically it was thymic tissue.
  • Bilateral neck exploration together with exploration of cervical thymic extensions was performed; adenoma was not found.
  • Adenoma was located by MIBI-SPECT/CT near the left border of jugulum.
  • [MeSH-major] Adenoma / diagnosis. Choristoma / complications. Neck. Parathyroid Glands. Parathyroid Neoplasms / diagnosis
  • [MeSH-minor] Child. Female. Humans. Hyperparathyroidism, Primary / etiology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19548602.001).
  • [ISSN] 1214-6994
  • [Journal-full-title] Prague medical report
  • [ISO-abbreviation] Prague Med Rep
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Czech Republic
  •  go-up   go-down


89. Freriks K, den Heijer M, Bonenkamp JJ, Biert J, Sweep CG, Hermus AR: [Intraoperative parathyroid hormone measurement in patients with primary hyperparathyroidism; particularly valuable for suspected solitary parathyroid adenoma and re-operation]. Ned Tijdschr Geneeskd; 2008 Jan 5;152(1):28-32
Genetic Alliance. consumer health - Hyperparathyroidism, primary.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Intraoperative parathyroid hormone measurement in patients with primary hyperparathyroidism; particularly valuable for suspected solitary parathyroid adenoma and re-operation].
  • OBJECTIVE: Analysis of the value of intraoperative parathormone (PTH) measurement in patients with primary hyperparathyroidism.
  • The success rate was correctly predicted as follows: in subgroups of patients with MEN-1 syndrome, 85%, patients after exclusion of MEN-1, 94%, and patients in whom a solitary adenoma was likely after preoperative localization studies, 97%.
  • In 13% of the total number of operations, PTH-measurements led to further exploration, removal of additional parathyroid tissue and normocalcemia postoperatively.
  • In patients without MEN-1 syndrome, in whom a solitary adenoma was likely on the basis of preoperative investigations, it was possible to limit the operation to a unilateral procedure in 87%.
  • CONCLUSION: In the majority of patients with primary hyperparathyroidism, intraoperative PTH-measurement in combination with preoperative imaging studies leads to patients being cured with a unilateral instead of a bilateral operation.
  • [MeSH-major] Adenoma / surgery. Hyperparathyroidism, Primary / blood. Monitoring, Intraoperative / methods. Parathyroid Hormone / blood. Parathyroid Neoplasms / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18240759.001).
  • [ISSN] 0028-2162
  • [Journal-full-title] Nederlands tijdschrift voor geneeskunde
  • [ISO-abbreviation] Ned Tijdschr Geneeskd
  • [Language] dut
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Parathyroid Hormone
  •  go-up   go-down


90. Cheng W, MacLennan GT, Lavertu P, Wasman JK: Giant intrathyroid parathyroid adenoma: a preoperative and intraoperative diagnostic challenge. Ear Nose Throat J; 2009 Mar;88(3):E1-3
MedlinePlus Health Information. consumer health - Thyroid Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant intrathyroid parathyroid adenoma: a preoperative and intraoperative diagnostic challenge.
  • We describe the case of an unusually large (giant) cystic intrathyroid parathyroid adenoma in a 73-year-old woman who had a 1-year history of hypercalcemia and a 5-year history of an asymptomatic enlargement of the left lobe of the thyroid.
  • This unique case highlights the potential difficulties that can arise in the evaluation of thyroid nodules in patients with hyperparathyroidism.
  • In some cases, including this one, even a thorough preoperative evaluation that includes fine-needle aspiration biopsy and radiographic and nuclear medicine studies may not allow for a definitive preoperative diagnosis.
  • The histologic overlap between thyroid and parathyroid lesions can also be problematic at the time of intraoperative frozen-section evaluation.
  • Intraoperative parathyroid hormone monitoring may be helpful in these difficult cases.
  • [MeSH-major] Intraoperative Care. Parathyroid Neoplasms / pathology. Parathyroid Neoplasms / surgery. Preoperative Care. Thyroid Neoplasms / pathology. Thyroid Neoplasms / surgery
  • [MeSH-minor] Aged. Biopsy, Needle. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Parathyroid Hormone / metabolism

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19291619.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Parathyroid Hormone
  •  go-up   go-down


91. Abboud B, Sleilaty G, Rabaa L, Daher R, Abou Zeid H, Jabbour H, Hachem K, Smayra T: Ultrasonography: highly accuracy technique for preoperative localization of parathyroid adenoma. Laryngoscope; 2008 Sep;118(9):1574-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ultrasonography: highly accuracy technique for preoperative localization of parathyroid adenoma.
  • OBJECTIVES/HYPOTHESIS: This study evaluates the accuracy of ultrasonography in guided unilateral parathyroidectomy to treat primary hyperparathyroidism.
  • METHODS: Two hundred fifty-three patients with primary hyperparathyroidism underwent preoperative ultrasonography.
  • Group 1 included the patients in whom the preoperative cervical ultrasound localized one abnormal parathyroid gland; these patients underwent unilateral surgical exploration of the neck under local anesthesia.
  • RESULTS: Sensitivity and positive predictive value of ultrasonography in detecting abnormal parathyroid gland were 96% and 98%, respectively.
  • Mediastinal and retroesophageal localizations of abnormal parathyroid gland adversely affected the accuracy of the ultrasound.
  • [MeSH-major] Adenoma / ultrasonography. Parathyroid Neoplasms / ultrasonography. Preoperative Care / methods. Ultrasonography, Doppler, Color / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Parathyroidectomy. Reproducibility of Results. Retrospective Studies. Sensitivity and Specificity

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18475203.001).
  • [ISSN] 1531-4995
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


92. Kataoka K, Taguchi M, Takeshita A, Miyakawa M, Takeuchi Y: Recurrence of primary hyperparathyroidism following spontaneous remission with intracapsular hemorrhage of a parathyroid adenoma. J Bone Miner Metab; 2008;26(3):295-7
MedlinePlus Health Information. consumer health - Bleeding.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Recurrence of primary hyperparathyroidism following spontaneous remission with intracapsular hemorrhage of a parathyroid adenoma.
  • A few patients with primary hyperparathyroidism (PHPT) have a chance of spontaneous remission by either infarction of or hemorrhage into or around the parathyroid adenoma.
  • Here we report a case with a recurrence of PHPT 4 months after spontaneous remission with acute intracapsular hemorrhage of parathyroid adenoma.
  • In the literature, only two cases have been reported to have experienced a recurrence of clinical features of PHPT after infarction but not hemorrhage of parathyroid adenomas.
  • Thus, the spontaneous remission of biological derangements in PHPT upon hemorrhage or infarction of parathyroid adenoma could be temporary.
  • [MeSH-major] Hemorrhage / complications. Hyperparathyroidism, Primary / etiology. Parathyroid Neoplasms / complications

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18470672.001).
  • [ISSN] 0914-8779
  • [Journal-full-title] Journal of bone and mineral metabolism
  • [ISO-abbreviation] J. Bone Miner. Metab.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 5
  •  go-up   go-down


93. Younes NA, Hadidi AM, Mahafzah WS, Tarawneh ES, Al-Khatib YF, Sroujieh AS: Accuracy of single versus combined use of ultrasonography or computed tomography in the localization of parathyroid adenoma. Saudi Med J; 2008 Feb;29(2):213-7
MedlinePlus Health Information. consumer health - CT Scans.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Accuracy of single versus combined use of ultrasonography or computed tomography in the localization of parathyroid adenoma.
  • OBJECTIVE: To assess the accuracy of a single versus combined use of ultrasound (US), or computed tomography (CT) in the localization of diseased parathyroid glands.
  • Preoperative ultrasonographic and CT findings were reviewed and compared to the intraoperative and pathologic diagnosis of diseased parathyroid glands.
  • Parathyroid adenoma was confirmed in 33 patients and hyperplasia of the parathyroid glands in 8 patients.
  • In 18 cases, the diagnosis of parathyroid disease was based on CT findings alone and in 9 patients the diagnosis was based on single US findings.
  • CONCLUSION: Neck CT scan evaluation has almost an equivalent sensitivity to combined CT and neck US in the preoperative localization of diseased parathyroid glands, however the combined use of these techniques provides the best diagnostic accuracy.
  • [MeSH-major] Adenoma / radiography. Adenoma / ultrasonography. Parathyroid Neoplasms / radiography. Parathyroid Neoplasms / ultrasonography. Tomography, X-Ray Computed
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Hyperparathyroidism / diagnosis. Male. Middle Aged. Predictive Value of Tests. Preoperative Care. Sensitivity and Specificity

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18246229.001).
  • [ISSN] 0379-5284
  • [Journal-full-title] Saudi medical journal
  • [ISO-abbreviation] Saudi Med J
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Saudi Arabia
  •  go-up   go-down


94. Kirk J, Au-Yong I, Ganatra R: Multimodality imaging of a retrosternal parathyroid adenoma with multiple brown tumors. Clin Nucl Med; 2009 Sep;34(9):555-9
MedlinePlus Health Information. consumer health - Bone Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multimodality imaging of a retrosternal parathyroid adenoma with multiple brown tumors.
  • Brown tumors of hyperparathyroidism are rare but can mimic metastatic disease on many imaging modalities.
  • We report the case of a patient presenting with symptomatic brown tumors of hyperparathyroidism due to a large retrosternal parathyroid adenoma, with histopathological correlation of both.
  • The initial imaging findings on plain radiography, computed tomography, and bone scintigraphy were nonspecific and difficult to differentiate from the more common diagnosis of metastatic disease.
  • Whole body sestamibi imaging however demonstrated increased uptake within both the mediastinal mass and multiple bone lesions leading to the correct diagnosis.
  • [MeSH-major] Bone Neoplasms / complications. Bone Neoplasms / diagnosis. Parathyroid Neoplasms / complications. Parathyroid Neoplasms / diagnosis
  • [MeSH-minor] Aged. Diagnosis, Differential. Female. Humans. Hyperparathyroidism / complications. Hyperparathyroidism / radiography. Hyperparathyroidism / ultrasonography. Thyroid Gland / radiography. Thyroid Gland / ultrasonography. Tomography, X-Ray Computed

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19692812.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


95. Ippolito G, Palazzo FF, Sebag F, De Micco C, Henry JF: Intraoperative diagnosis and treatment of parathyroid cancer and atypical parathyroid adenoma. Br J Surg; 2007 May;94(5):566-70

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intraoperative diagnosis and treatment of parathyroid cancer and atypical parathyroid adenoma.
  • BACKGROUND: Distinction of parathyroid cancer from atypical parathyroid adenoma (APA) at operation is difficult.
  • The aim of this study was to determine whether parathyroid cancer and APA have different operative findings and long-term outcomes.
  • METHODS: A retrospective review was undertaken of patients with suspicious or malignant parathyroid tumours treated between 1974 and 2005.
  • Parathyroid cancer was defined as a lesion with vascular or tissue invasion, and APA as a neoplasm with broad fibrous bands, trabecular growth, mitosis and nuclear atypia.
  • RESULTS: Twenty-seven patients with suspicious or malignant parathyroid tumours were identified.
  • After histological review, parathyroid cancer was confirmed in 11 patients (group 1) and 16 tumours were classified as APA (group 2).
  • CONCLUSION: Operative findings cannot distinguish APA from parathyroid cancer reliably.
  • [MeSH-major] Adenoma / diagnosis. Parathyroid Neoplasms / diagnosis. Parathyroidectomy / methods
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Diagnosis, Differential. Female. Humans. Intraoperative Period. Male. Middle Aged. Neoplasm Recurrence, Local / etiology. Prognosis. Retrospective Studies. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Br J Surg. 2007 Aug;94(8):1043; author reply 1043-4 [17636522.001]
  • [CommentIn] Br J Surg. 2007 Aug;94(8):1042-3; author reply 1043-4 [17636521.001]
  • (PMID = 17380564.001).
  • [ISSN] 0007-1323
  • [Journal-full-title] The British journal of surgery
  • [ISO-abbreviation] Br J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  •  go-up   go-down


96. Berri RN, Lloyd LR: Detection of parathyroid adenoma in patients with primary hyperparathyroidism: the use of office-based ultrasound in preoperative localization. Am J Surg; 2006 Mar;191(3):311-4
Genetic Alliance. consumer health - Hyperparathyroidism, primary.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Detection of parathyroid adenoma in patients with primary hyperparathyroidism: the use of office-based ultrasound in preoperative localization.
  • BACKGROUND: The purpose of this investigation is to show that preoperative localization of the parathyroid gland using office-based ultrasound (US) and Tc-99m sestamibi scan is superior to all other approaches in detecting a parathyroid adenoma.
  • METHODS: We performed a retrospective analysis of 43 patients who underwent parathyroidectomy for primary hyperparathyroidism.
  • RESULTS: In 42 of 43 patients, office-based US performed by a surgeon and sestamibi scintigraphy successfully detected the location of a parathyroid abnormality (42/43 cases, sensitivity = 98%, P < .05 =.0001).
  • Office-based US localized the abnormal gland to the specific side (right/left) in 36 of 43 cases (84%).
  • US localized the abnormal gland to the specific quadrant (34/43 cases [79%] sensitivity versus 23/43 cases [53%] sensitivity using sestamibi scan alone to localize to the specific quadrant, P = .03).
  • CONCLUSION: It is clear that the combined modalities of office-based US and sestamibi scintigraphy in preoperative localization have a high success rate and should be considered in parathyroid surgery.
  • [MeSH-major] Adenoma / ultrasonography. Hyperparathyroidism, Primary / ultrasonography. Parathyroid Neoplasms / ultrasonography

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16490537.001).
  • [ISSN] 0002-9610
  • [Journal-full-title] American journal of surgery
  • [ISO-abbreviation] Am. J. Surg.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


97. Grosso I, Sargiotto A, D'Amelio P, Tamone C, Gasparri G, De Filippi PG, Picciotto G, Isaia G: Preoperative localization of parathyroid adenoma with sonography and 99mTc-sestamibi scintigraphy in primary hyperparathyroidism. J Clin Ultrasound; 2007 May;35(4):186-90
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Preoperative localization of parathyroid adenoma with sonography and 99mTc-sestamibi scintigraphy in primary hyperparathyroidism.
  • PURPOSE: To evaluate the sensitivity, specificity, and usefulness of dual-phase 99mTc-Sestamibi scintigraphy (SS) and sonography (US) of the neck, alone and in combination, as noninvasive adenoma localizing procedures in patients with primary hyperparathyroidism prior to parathyroidectomy.
  • METHODS: We retrospectively analyzed the charts of 79 patients with parathyroid (PT) adenomas and confirmed diagnosis of hyperparathyroidism who were evaluated with SS and US prior to successful parathyroidectomy.
  • RESULTS: Ninety-three adenomas were removed during bilateral neck exploration.
  • CONCLUSIONS: No benefit was gained from using both SS and US for the preoperative localization of PT adenomas in patients with primary hyperparathyroidism.
  • US, when performed by a skilled operator, is a reliable tool for PT adenoma localization.
  • [MeSH-major] Adenoma / ultrasonography. Hyperparathyroidism, Primary / ultrasonography. Parathyroid Neoplasms / ultrasonography. Radiopharmaceuticals. Technetium Tc 99m Sestamibi
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Intraoperative Care. Male. Middle Aged. Parathyroid Hormone / analysis. Parathyroidectomy. Postoperative Complications. Recurrent Laryngeal Nerve / physiopathology. Retrospective Studies. Sensitivity and Specificity. Thyroid Gland / radionuclide imaging. Thyroid Gland / ultrasonography. Thyroid Nodule / radionuclide imaging. Thyroid Nodule / ultrasonography. Vocal Cord Paralysis / etiology

  • Genetic Alliance. consumer health - Hyperparathyroidism, primary.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17354248.001).
  • [ISSN] 0091-2751
  • [Journal-full-title] Journal of clinical ultrasound : JCU
  • [ISO-abbreviation] J Clin Ultrasound
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Parathyroid Hormone; 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


98. Costanzo M, Terminella A, Marziani A, Chisari A, Missiato A, Cannizzaro MA: Giant mediastinal parathyroid adenoma: a case report. Ann Ital Chir; 2009 Jan-Feb;80(1):55-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant mediastinal parathyroid adenoma: a case report.
  • Neck and chest TC and 'TC sestamibi scintigraphy showed the presence of a 7 cm hyperfunctional ectopic parathyroid tissue in the postero-superior mediastinum infiltrating oesophagus.
  • Through right postero-lateral thoracotomy and mediastinal pleura incision, the adenoma excision was carried out.
  • The histological examination revealed a potentially malignant parathyroid adenoma with infiltration, without over-reaching the capsule.
  • Today, the tendency to minimally invasive surgery, an accurate preoperative localization of the adenoma and the use of techniques such as intra-surgical nuclear mapping through manual gamma probes, selective angiography, venous intraoperative dosage of PTH and intra-surgical ultrasound scan.
  • [MeSH-major] Adenocarcinoma / pathology. Choristoma / pathology. Mediastinum / pathology. Parathyroid Glands. Parathyroid Neoplasms / pathology
  • [MeSH-minor] Adenoma / pathology. Aged. Female. Humans. Parathyroidectomy. Radiopharmaceuticals. Technetium Tc 99m Sestamibi. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19537125.001).
  • [ISSN] 0003-469X
  • [Journal-full-title] Annali italiani di chirurgia
  • [ISO-abbreviation] Ann Ital Chir
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down


99. Akçay MN, Akçay G: The predictive value of routine preoperative laboratory parameters in patients with sporadic and solitary parathyroid adenoma. Eurasian J Med; 2009 Aug;41(2):108-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The predictive value of routine preoperative laboratory parameters in patients with sporadic and solitary parathyroid adenoma.
  • OBJECTIVE: Primary hyperparathyroidism (pHPT) is a disease in which the diagnosis depends increasingly on laboratory tests since the majority of patients are elderly people without typical symptoms.
  • MATERIALS AND METHODS: We calculated the specificity and sensitivity rates, and positive predictive value of blood calcium (Ca), phosphorous (P), alkaline phosphatase (ALP), and intact parathormone (iPTH) levels in patients with sporadic and solitary parathyroid adenoma (PA).
  • With respect to the diagnosis of pHPT, the sensitivity of blood levels of iPTH, P, Ca, and ALP were 96%, 94%, 81%, and 73%, respectively.
  • The specificity and positive predictive value of all parameters were 100% for the diagnosis of PA.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 25610079.001).
  • [ISSN] 1308-8734
  • [Journal-full-title] The Eurasian journal of medicine
  • [ISO-abbreviation] Eurasian J Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Turkey
  • [Other-IDs] NLM/ PMC4261463
  • [Keywords] NOTNLM ; Adenoma / Parathyroid / Routine laboratory parameters
  •  go-up   go-down


100. Murphy AD, Andrews EJ, Ishtiaq A, Jawad A, McCarthy PA, O'Keeffe D, Dunne F, Quill DS: Sestamibi scan-directed, minimally invasive video-assisted parathyroidectomy: an effective treatment for solitary parathyroid adenoma. Ir J Med Sci; 2007 Dec;176(4):283-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sestamibi scan-directed, minimally invasive video-assisted parathyroidectomy: an effective treatment for solitary parathyroid adenoma.
  • BACKGROUND: Solitary adenomas have been shown to be responsible for almost 90% of cases of primary hyperparathyroidism.
  • RESULTS: Thirty-three (82%) patients had a localized solitary adenoma on sestamibi scan.
  • When pre-operative sestamibi scanning was correlated with pathological diagnosis it was shown to have a sensitivity of 82% and positive predictive value of 94%.
  • CONCLUSION: Pre-operative sestamibi scan localization of a parathyroid adenoma offers a 94% positive predictive value for adenoma location.
  • This facilitates MIVA parathyroidectomy to be used effectively to treat primary hyperparathyroidism in the majority of patients.
  • [MeSH-major] Adenoma / radionuclide imaging. Adenoma / surgery. Parathyroid Neoplasms / radionuclide imaging. Parathyroid Neoplasms / surgery. Tomography, Emission-Computed, Single-Photon. Video-Assisted Surgery / methods
  • [MeSH-minor] Aged. Cohort Studies. Female. Humans. Hyperparathyroidism / diagnosis. Hyperparathyroidism / etiology. Male. Middle Aged. Minimally Invasive Surgical Procedures / methods. Neoplasm Invasiveness / pathology. Parathyroidectomy / methods. Predictive Value of Tests. Preoperative Care. Probability. Risk Assessment. Sensitivity and Specificity. Statistics, Nonparametric. Technetium Tc 99m Sestamibi. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17724570.001).
  • [ISSN] 1863-4362
  • [Journal-full-title] Irish journal of medical science
  • [ISO-abbreviation] Ir J Med Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 971Z4W1S09 / Technetium Tc 99m Sestamibi
  •  go-up   go-down






Advertisement