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1. Brown IS, Whiteman DC, Lauwers GY: Foveolar type dysplasia in Barrett esophagus. Mod Pathol; 2010 Jun;23(6):834-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Foveolar type dysplasia in Barrett esophagus.
  • Adenocarcinoma of the lower esophagus and esophagogastric junction is increasing in incidence in Western countries.
  • A metaplasia (Barrett esophagus)-dysplasia-carcinoma sequence induced by gastroesophageal reflux disease is established.
  • Esophagogastrectomy cases from 41 patients with glandular dysplasia with and without associated invasive adenocarcinoma of the lower esophagus were evaluated for expression of MUC2, MUC5AC, CDX2, villin, Ki67 and p53.
  • In conclusion, our study provides evidence for a non intestinal pathway to neoplastic development in Barrett esophagus, that is, gastric metaplasia-foveolar dysplasia-adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma / pathology. Barrett Esophagus / pathology. Esophageal Neoplasms / pathology. Esophagus / pathology. Precancerous Conditions / pathology

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  • (PMID = 20228780.001).
  • [ISSN] 1530-0285
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CDX2 protein, human; 0 / Homeodomain Proteins; 0 / Ki-67 Antigen; 0 / MUC2 protein, human; 0 / MUC5AC protein, human; 0 / Microfilament Proteins; 0 / Mucin 5AC; 0 / Mucin-2; 0 / TP53 protein, human; 0 / Tumor Suppressor Protein p53; 0 / villin
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2. Alexander CL, Urbanski SJ, Hilsden R, Rabin H, MacNaughton WK, Beck PL: The risk of gastrointestinal malignancies in cystic fibrosis: case report of a patient with a near obstructing villous adenoma found on colon cancer screening and Barrett's esophagus. J Cyst Fibros; 2008 Jan;7(1):1-6
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  • [Title] The risk of gastrointestinal malignancies in cystic fibrosis: case report of a patient with a near obstructing villous adenoma found on colon cancer screening and Barrett's esophagus.
  • CF patients that do develop gastrointestinal malignancies do so at an earlier age and there is often a lag in the diagnosis and management of these individuals.
  • We present a 39 year old male CF patient that underwent a colonoscopy for colon cancer screening and a large, near obstructing, villous adenoma of his ileum was found.
  • An upper endoscopy revealed a long segment of Barrett's esophagus with no evidence of dysplasia.
  • [MeSH-major] Adenoma, Villous / complications. Barrett Esophagus / complications. Cystic Fibrosis / complications. Ileal Neoplasms / complications


3. Kiverniti E, Kazi R, Rhys-Evans P, Nippah R: Airway obstruction due to giant non-parathyroid hormone-producing parathyroid adenoma. J Cancer Res Ther; 2008 Oct-Dec;4(4):197-9

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  • [Title] Airway obstruction due to giant non-parathyroid hormone-producing parathyroid adenoma.
  • We present a case of a 39-year-old female patient with acute stridor due to a large tumor located at the level of the upper third of her thoracic esophagus.
  • Parathyroid gland tumors are unusual in the differential diagnosis of mediastinal tumors.
  • The eventual diagnosis on histology was parathyroid adenoma.
  • [MeSH-minor] Adenoma. Adult. Airway Obstruction. Esophagus / metabolism. Female. Humans. Mediastinal Neoplasms / metabolism. Medical Oncology / methods. Parathyroid Hormone / metabolism. Tomography, X-Ray Computed / methods. Treatment Outcome

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  • (PMID = 19052395.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Parathyroid Hormone
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4. Haveri H, Westerholm-Ormio M, Lindfors K, Mäki M, Savilahti E, Andersson LC, Heikinheimo M: Transcription factors GATA-4 and GATA-6 in normal and neoplastic human gastrointestinal mucosa. BMC Gastroenterol; 2008;8:9

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  • Both factors were also present in Barrett's esophagus and metaplasia of the stomach.
  • [MeSH-major] Adenocarcinoma / genetics. Adenoma / genetics. Colonic Neoplasms / genetics. GATA4 Transcription Factor / metabolism. GATA6 Transcription Factor / metabolism. Gastric Mucosa / metabolism. Rectal Neoplasms / genetics
  • [MeSH-minor] Adolescent. Adult. Aged. Barrett Esophagus / genetics. Barrett Esophagus / pathology. Biopsy. Child. Child, Preschool. Esophagus / metabolism. Esophagus / pathology. Gastritis / genetics. Gastritis / pathology. Gastritis, Atrophic / genetics. Gastritis, Atrophic / pathology. Humans. Immunohistochemistry. Infant. Middle Aged. RNA, Messenger / analysis

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  • (PMID = 18405344.001).
  • [ISSN] 1471-230X
  • [Journal-full-title] BMC gastroenterology
  • [ISO-abbreviation] BMC Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / GATA4 Transcription Factor; 0 / GATA6 Transcription Factor; 0 / RNA, Messenger
  • [Other-IDs] NLM/ PMC2323380
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5. Grimm EE, Rulyak SJ, Sekijima JH, Yeh MM: Canalicular adenoma arising in the esophagus. Arch Pathol Lab Med; 2007 Oct;131(10):1595-7
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  • [Title] Canalicular adenoma arising in the esophagus.
  • To our knowledge, canalicular adenoma arising in the esophagus has never been described in the English literature.
  • Here we report a canalicular adenoma occurring in the esophagus.
  • [MeSH-major] Adenoma / pathology. Esophageal Neoplasms / pathology

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  • (PMID = 17922600.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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6. Loffeld SM, Loffeld RJ: Colorectal cancer and adenomas are rare in individuals of Turkish descent living in the Zaanstreek region in the Netherlands. J Cancer Res Clin Oncol; 2010 Sep;136(9):1439-43
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  • Screening and detection of its precursor lesion, the adenoma could prevent development of colorectal cancer.
  • AIM: To evaluate the prevalence of colorectal cancer and adenoma in patients living in the Zaanstreek region, the Netherlands, and correlate these findings with ethnicity.
  • All available histological data were retrieved in order to confirm the endoscopic diagnosis.
  • CONCLUSION: Colorectal cancer and colonic adenoma are rare in patients of Turkish descent living in the Zaanstreek region, the Netherlands.
  • [MeSH-major] Adenoma / epidemiology. Colorectal Neoplasms / epidemiology

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  • (PMID = 20140623.001).
  • [ISSN] 1432-1335
  • [Journal-full-title] Journal of cancer research and clinical oncology
  • [ISO-abbreviation] J. Cancer Res. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC2908754
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7. do Prado RF, Consolaro A, Taveira LA: Expression of betacatenin in carcinoma in pleomorphic adenoma, pleomorphic adenoma and normal salivary gland: an immunohistochemical study. Med Oral Patol Oral Cir Bucal; 2006 May;11(3):E247-51
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  • [Title] Expression of betacatenin in carcinoma in pleomorphic adenoma, pleomorphic adenoma and normal salivary gland: an immunohistochemical study.
  • Beta-catenin is a cell adhesion molecule associated with the invasion and metastasis of carcinomas of the head and neck, esophagus.
  • CONCLUSIONS: The present study showed participation of the loss of beta-catenin adhesion molecule in the development of pleomorphic adenoma, and that the cytoplasmic accumulation of the molecule takes part in the malignant transformation of the pleomorphic adenoma into carcinoma in pleomorphic adenoma.
  • [MeSH-major] Adenoma, Pleomorphic / metabolism. Carcinoma / metabolism. Neoplasms, Multiple Primary / metabolism. Salivary Gland Neoplasms / metabolism. Salivary Glands / metabolism. beta Catenin / biosynthesis

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  • (PMID = 16648762.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / beta Catenin
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8. Gyorffy H: [Study of claudins and prognostic factors in some gastrointestinal diseases]. Magy Onkol; 2009 Dec;53(4):377-83
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  • I. We explored the changes of CLDN expression in Barrett's esophagus and related adenocarcinoma.
  • CLDN2 and -3 expression in Barrett's esophagus was higher than in normal foveolar epithelium.
  • The similar CLDN expression profile of Barrett's esophagus and adenocarcinoma supports their sequential development.
  • Colorectal adenoma and adenocarcinoma could not be differentiated according to their CLDN profile.
  • Intestinal metaplasias of Barrett's esophagus and stomach show similar CLDN profile to small bowel epithelium.
  • [MeSH-minor] Adenocarcinoma / metabolism. Adolescent. Adult. Aged. Aged, 80 and over. Barrett Esophagus / metabolism. Carcinoma, Squamous Cell / metabolism. Child. Child, Preschool. Claudin-3. Female. Fluorescent Antibody Technique. Gastrointestinal Stromal Tumors / metabolism. Gene Expression Regulation, Neoplastic. Hemangiosarcoma / metabolism. Humans. Immunohistochemistry. Leiomyosarcoma / metabolism. Male. Membrane Proteins / metabolism. Middle Aged. Predictive Value of Tests. Prognosis. RNA, Messenger / metabolism. Risk Factors. Young Adult

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  • (PMID = 20071310.001).
  • [ISSN] 0025-0244
  • [Journal-full-title] Magyar onkologia
  • [ISO-abbreviation] Magy Onkol
  • [Language] hun
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Hungary
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CLDN3 protein, human; 0 / Claudin-3; 0 / Claudins; 0 / Membrane Proteins; 0 / RNA, Messenger
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9. Kushima R, Vieth M, Mukaisho K, Sakai R, Okabe H, Hattori T, Neuhaus H, Borchard F, Stolte M: Pyloric gland adenoma arising in Barrett's esophagus with mucin immunohistochemical and molecular cytogenetic evaluation. Virchows Arch; 2005 May;446(5):537-41
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pyloric gland adenoma arising in Barrett's esophagus with mucin immunohistochemical and molecular cytogenetic evaluation.
  • Pyloric gland adenoma is a recently described and very rare entity.
  • The occurrence of adenoma is very unusual in Barrett's epithelium of the esophagus.
  • We report a case of esophageal polyp showing the features of pyloric gland adenoma, which was surrounded by so-called specialized columnar epithelium.
  • This is the first case of pyloric gland adenoma found to arise in Barrett's epithelium of the esophagus, showing its unstable and precancerous nature.
  • [MeSH-major] Adenoma / diagnosis. Barrett Esophagus / pathology. Cytogenetic Analysis. Gastric Mucosa. Mucins / analysis. Stomach Neoplasms / diagnosis

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  • (PMID = 15838649.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Ki-67 Antigen; 0 / MUC5AC protein, human; 0 / MUC6 protein, human; 0 / Mucin 5AC; 0 / Mucin-6; 0 / Mucins
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10. Andreu Garcia M: [Esophageal adenoma-carcinoma and Barrett's esophagus. Gastric adenocarcinoma and Helicobacter pylori]. Gastroenterol Hepatol; 2008 Oct;31 Suppl 4:66-9
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  • [Title] [Esophageal adenoma-carcinoma and Barrett's esophagus. Gastric adenocarcinoma and Helicobacter pylori].
  • In the last two decades, the incidence of esophageal cancer has progressively increased, especially that of adenocarcinomas localized in the esophagogastric junction.
  • In the meeting of the American Gastroenterological Association, notable among all the studies presented on the prevention and treatment of esophageal and gastric cancer were the following contributions: the use of clinical practice guidelines for the prevention and surveillance of Barrett's esophagus (BE) should be improved; treatment with proton pump inhibitors does not seem to reduce the risk of esophageal cancer; endoscopic therapy of intramucosal cancer through complete mucosal resection is effective; Helicobacter pylori eradication prevents the development of metachronous gastric cancer in patients treated for a first intramucosal adenocarcinoma through endoscopic resection; the risk of developing gastric cancer is 6 times higher in patients with mucosa-associated lymphoid tissue (MALT) lymphoma than in the general population; and photodynamic therapy may be an alternative for the treatment of "invisible" gastric adenocarcinoma, which should be followed-up endoscopically.
  • [MeSH-major] Adenocarcinoma / etiology. Barrett Esophagus / complications. Esophageal Neoplasms / etiology. Helicobacter Infections / complications. Helicobacter pylori. Stomach Neoplasms / etiology


11. Tischoff I, Tannapfel A: Barrett's esophagus: can biomarkers predict progression to malignancy? Expert Rev Gastroenterol Hepatol; 2008 Oct;2(5):653-63
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  • [Title] Barrett's esophagus: can biomarkers predict progression to malignancy?
  • Barrett's esophagus (BE) is one of the most common premalignant lesions and can progress to esophageal adenocarcinoma.
  • It is characterized histologically by a specialized intestinal metaplasia that replaces the squamous epithelium of the distal esophagus, and is associated with chronic gastroesophageal reflux disease and obesity.
  • Similar to the adenoma-carcinoma sequence of colorectal carcinomas, esophageal adenocarcinoma develops through progression from BE to low- and high-grade dysplasia, then to adenocarcinoma with accumulation of genetic and epigenetic abnormalities.
  • Dysplasia is the most predictive marker for risk of esophageal adenocarcinoma, whereas endoscopic and histological diagnoses are still the gold standard for surveillance of patients with BE.
  • Several studies have identified candidate biomarkers that may have predictive value and may serve as additional factors for the risk assessment of esophageal adenocarcinoma.
  • [MeSH-major] Barrett Esophagus / metabolism. Biomarkers, Tumor / metabolism. Esophageal Neoplasms / metabolism

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  • (PMID = 19072343.001).
  • [ISSN] 1747-4132
  • [Journal-full-title] Expert review of gastroenterology & hepatology
  • [ISO-abbreviation] Expert Rev Gastroenterol Hepatol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 97
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12. Ogawa T, Tsuji E, Kanauchi H, Yamada K, Mimura Y, Kaminishi M: Excision of postesophageal parathyroid adenoma in posterior mediastinum with intraoperative 99mTechnetium sestamibi scanning. Ann Thorac Surg; 2007 Nov;84(5):1754-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Excision of postesophageal parathyroid adenoma in posterior mediastinum with intraoperative 99mTechnetium sestamibi scanning.
  • We present a case of retroesophageal mediastinal parathyroid adenoma that developed in the left superior parathyroid gland.
  • [MeSH-major] Adenoma / surgery. Choristoma / surgery. Mediastinal Neoplasms / surgery. Parathyroid Neoplasms / surgery. Technetium Tc 99m Sestamibi
  • [MeSH-minor] Aged. Esophagus. Female. Humans

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  • (PMID = 17954108.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 971Z4W1S09 / Technetium Tc 99m Sestamibi
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13. Harada O, Ota H, Katsuyama T, Hidaka E, Ishizaka K, Nakayama J: Esophageal gland duct adenoma: immunohistochemical comparison with the normal esophageal gland and ultrastractural analysis. Am J Surg Pathol; 2007 Mar;31(3):469-75
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  • [Title] Esophageal gland duct adenoma: immunohistochemical comparison with the normal esophageal gland and ultrastractural analysis.
  • Esophageal gland duct adenomas are extremely rare tumors.
  • Esophageal gland duct adenoma was incidentally found in the lower esophagus.
  • Immunohistochemical analysis revealed that the tumor were diffusely positive for the S100 protein with preserved alpha-SMA-positive myoepithelial cell layers and a characteristic cytokeratin expression pattern similar to that in normal esophageal gland ducts (CK5/6+++, CK7+++, CK17+, CK18+, CK19+++, CK20-, HMWCK+++).
  • This is the first report that refers to the ultrastructural findings of an esophageal gland duct adenoma and describes terminal duct differentiation.
  • We believe that the possibility of an esophageal gland duct adenoma should be considered when diagnosing a ductal or glandular lesion of the esophagus.
  • [MeSH-major] Adenoma / pathology. Esophageal Neoplasms / pathology. Esophagus / pathology

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  • (PMID = 17325490.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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14. Odze RD, Maley CC: Neoplasia without dysplasia: lessons from Barrett esophagus and other tubal gut neoplasms. Arch Pathol Lab Med; 2010 Jun;134(6):896-906
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neoplasia without dysplasia: lessons from Barrett esophagus and other tubal gut neoplasms.
  • Particular attention is given to Barrett esophagus, a chronic inflammatory condition in which early molecular and morphologic events that drive carcinogenesis are best understood.
  • DATA SOURCES: Selected references and abstracts were obtained by a PubMed (US National Library of Medicine) search by using the search headings neoplasia, preneoplasia, dysplasia, adenoma, serrated polyps, and Barrett's esophagus between the years 1980 and 2009.
  • All of these lesions, such as squamous dysplasia of the esophagus, dysplasia in Barrett esophagus, and hyperplastic/serrated polyps of the colon, represent early neoplastic precursor lesions but without conventional histologic features of dysplasia.
  • [MeSH-major] Barrett Esophagus / pathology. Gastrointestinal Neoplasms / pathology. Precancerous Conditions / pathology

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  • (PMID = 20524867.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 98
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15. Wolfsen HC: Endoluminal therapy for esophageal disease: an introduction. Gastrointest Endosc Clin N Am; 2010 Jan;20(1):1-10, v

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoluminal therapy for esophageal disease: an introduction.
  • It provides a background to Barrett esophagus (BE), exploring the risk of progression to dysplasia and esophageal adenocarcinoma.
  • Two premalignant conditions, BE and colon adenoma, are compared, including their progression to esophageal adenocarcinoma and colon and rectal carcinoma, respectively.
  • [MeSH-major] Barrett Esophagus / surgery. Esophagus / surgery
  • [MeSH-minor] Adenocarcinoma / etiology. Adenocarcinoma / prevention & control. Adenoma / pathology. Carcinoma / etiology. Carcinoma / prevention & control. Colonic Neoplasms / etiology. Colonic Neoplasms / pathology. Colonic Neoplasms / prevention & control. Disease Progression. Esophageal Neoplasms / etiology. Esophageal Neoplasms / prevention & control. Humans. Precancerous Conditions / etiology. Precancerous Conditions / pathology. Precancerous Conditions / prevention & control. Rectal Neoplasms / etiology. Rectal Neoplasms / prevention & control. Risk Assessment

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  • (PMID = 19951790.001).
  • [ISSN] 1558-1950
  • [Journal-full-title] Gastrointestinal endoscopy clinics of North America
  • [ISO-abbreviation] Gastrointest. Endosc. Clin. N. Am.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 84
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16. Csendes A, Burgos AM, Smok G, Beltran M: Endoscopic and histologic findings of the foregut in 426 patients with morbid obesity. Obes Surg; 2007 Jan;17(1):28-34
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  • RESULTS: Pathological findings at the esophagus were seen in 55% of the patients, mainly related to reflux esophagitis.
  • Barrett's esophagus was seen in 5.8%.
  • Antral adenoma with low-grade dysplasia was found in 1 patient, and 1 carcinoid tumor. H. pylori was present in 53% of the patients, mainly in the antrum.
  • After surgery, if Barrett's esophagus was present, endoscopic surveillance is recommended.
  • [MeSH-minor] Adolescent. Adult. Aged. Duodenum / pathology. Endoscopy. Esophagus / pathology. Female. Gastric Bypass. Humans. Intestinal Mucosa / pathology. Male. Middle Aged. Prospective Studies

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  • [CommentIn] Obes Surg. 2007 Jul;17(7):993; author reply 994 [17894165.001]
  • (PMID = 17355765.001).
  • [ISSN] 0960-8923
  • [Journal-full-title] Obesity surgery
  • [ISO-abbreviation] Obes Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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17. Manner H, May A, Rabenstein T, Pech O, Nachbar L, Enderle MD, Gossner L, Ell C: Prospective evaluation of a new high-power argon plasma coagulation system (hp-APC) in therapeutic gastrointestinal endoscopy. Scand J Gastroenterol; 2007 Mar;42(3):397-405
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  • Main indications were additive ablation therapy in Barrett's esophagus, palliative treatment of esophageal cancer, gastric polyps/carcinomas, angiodysplasias, Zenker's diverticula, and duodenal adenomas.
  • For palliative tumor ablation in the esophagus, the number of sessions was 2.3 (1-5).
  • [MeSH-minor] Adenoma / surgery. Adult. Aged. Aged, 80 and over. Angiodysplasia / surgery. Barrett Esophagus / surgery. Carcinoma, Squamous Cell / surgery. Catheter Ablation. Duodenal Neoplasms / surgery. Esophageal Neoplasms / surgery. Female. Follow-Up Studies. Germany. Humans. Intestinal Polyps / surgery. Male. Middle Aged. Prospective Studies. Stomach Neoplasms / surgery. Treatment Outcome. Zenker Diverticulum / surgery

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  • (PMID = 17354121.001).
  • [ISSN] 0036-5521
  • [Journal-full-title] Scandinavian journal of gastroenterology
  • [ISO-abbreviation] Scand. J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Norway
  • [Chemical-registry-number] 67XQY1V3KH / Argon
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18. Gockel I, Trinh TT, Mildenberger P, Oberholzer K, Schmitt T, Eckardt VF, Junginger T: [Achalasia or pseudoachalasia? Problems of diagnostic and treatment decisions in two cases]. Dtsch Med Wochenschr; 2008 Feb;133(7):290-4
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  • Barium meal in patient 1 revealed fixed narrowing in the region of the esophageal hiatus.
  • The inferior esophageal sphincter was closed but opened under pressure during esophagogastroscopy.
  • At computed tomography (CT) of the thorax and abdomen an esophageal fistula was detected and bronchoscopy confirmed its opening into the esophagus.
  • Barium meal in patient 2 (done at another hospital) demonstrated a spastic esophagus.
  • Manometry of the esophagus revealed at rest an abnormal increase in the inferior esophageal sphincter without relaxation.
  • DIAGNOSIS, TREATMENT AND COURSE: Patient 1 had an achalasia and an esophagogastric fistula with recurrent aspiration pneumonia, bronchial carcinoma being excluded.
  • In patient 2 an isolated achalasia had at first been suspected and botulinum toxin injected into the inferior esophageal sphincter.
  • CT of the thorax and abdomen established the diagnosis of a pseudoachalasia due to an adenoma of the cardia, proven by biopsy at an exploratory laparotomy.
  • A stent was implanted in the esophagus: the postoperative course was without complication.
  • The differential diagnosis between the two conditions may be difficult with routine methods and other imaging modalities: exploratory surgery may be necessary for a definitive diagnosis.
  • [MeSH-major] Deglutition Disorders / etiology. Esophageal Achalasia / diagnosis. Esophageal Achalasia / therapy. Gastroesophageal Reflux / etiology
  • [MeSH-minor] Adenoma / complications. Adenoma / diagnosis. Adenoma / surgery. Age Factors. Aged, 80 and over. Bronchoscopy. Cardia. Diagnosis, Differential. Endoscopy, Digestive System. Esophageal Fistula / complications. Esophageal Fistula / diagnosis. Esophageal Fistula / surgery. Female. Gastric Fistula / complications. Gastric Fistula / diagnosis. Gastric Fistula / surgery. Humans. Male. Manometry. Middle Aged. Stents. Stomach Neoplasms / complications. Stomach Neoplasms / diagnosis. Stomach Neoplasms / surgery. Tomography, X-Ray Computed. Weight Loss

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  • (PMID = 18253919.001).
  • [ISSN] 1439-4413
  • [Journal-full-title] Deutsche medizinische Wochenschrift (1946)
  • [ISO-abbreviation] Dtsch. Med. Wochenschr.
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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19. Nagano Y, Sekido H, Matsuoi K, Ohtsuki K, Gorai K, Kunisaki C, Ike H, Imada T, Shimada H: Successful pancreatoduodenectomy for carcinoma of the ampulla of vater after esophagectomy with remnant gastrectomy. Hepatogastroenterology; 2005 May-Jun;52(63):933-5
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  • In his past history, he had undergone distal gastrectomy for a gastric adenoma 17 years before.
  • Double cancer of the ampulla of Vater and the esophagus are extremely rare, with only 4 cases reported.
  • [MeSH-major] Adenocarcinoma / surgery. Ampulla of Vater / surgery. Common Bile Duct Neoplasms / surgery. Esophageal Neoplasms / surgery. Esophagectomy. Gastrectomy. Gastric Stump / surgery. Neoplasms, Multiple Primary / surgery. Pancreaticoduodenectomy. Postoperative Complications / surgery
  • [MeSH-minor] Adenoma / surgery. Humans. Lymph Node Excision. Middle Aged. Neoplasm Invasiveness. Reoperation. Stomach Neoplasms / surgery

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  • (PMID = 15966235.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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20. Hariri LP, Tumlinson AR, Wade NH, Besselsen DG, Utzinger U, Gerner EW, Barton JK: Ex vivo optical coherence tomography and laser-induced fluorescence spectroscopy imaging of murine gastrointestinal tract. Comp Med; 2007 Apr;57(2):175-85
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  • Segments (length, 2.5 cm) of duodenum and lower colon and the entire esophagus were imaged ex-vivo with combined OCT and LIE We evaluated 30 normal mice (A/J and 10- and 21-wk-old and retired breeder C57BL/6J) and 10 mice each of 2 strains modeling colon cancer and IBD (Apc(Min) and IL2-deficient mice, respectively).
  • Histology was used to classify tissue regions as normal, Peyer patch, dysplasia, adenoma, or IBD.

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  • (PMID = 17536618.001).
  • [ISSN] 1532-0820
  • [Journal-full-title] Comparative medicine
  • [ISO-abbreviation] Comp. Med.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / R01 CA109385; United States / NIAID NIH HHS / AI / SWAIR-CA83148
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
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21. Yoshida S, Tanaka S, Hirata M, Mouri R, Kaneko I, Oka S, Yoshihara M, Chayama K: Optical biopsy of GI lesions by reflectance-type laser-scanning confocal microscopy. Gastrointest Endosc; 2007 Jul;66(1):144-9
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  • Twenty-two areas of 15 untreated specimens from the esophagus (normal mucosa, n=1; dysplasia, n=1), stomach (normal mucosa, n=3; cancer, n=5), and colon (normal mucosa, n=3; adenoma, n=8; cancer, n=1) were examined.
  • RESULTS: Smooth nuclei of cells were visualized by LCM in the normal esophageal-mucosa specimen.
  • Nuclei were visualized in 5 of 8 colonic-adenoma specimens.
  • CONCLUSIONS: LCM provides instant microscopic images, and, with further technical improvement, in the future this novel method will aid in immediate diagnosis under endoscopy without the need for tissue biopsy.
  • [MeSH-major] Adenocarcinoma / pathology. Barrett Esophagus / pathology. Biopsy / methods. Colonic Neoplasms / pathology. Microscopy, Confocal. Stomach Neoplasms / pathology

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  • [CommentIn] Gastrointest Endosc. 2007 Jul;66(1):150-3 [17591489.001]
  • (PMID = 17591488.001).
  • [ISSN] 0016-5107
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Controlled Clinical Trial; Journal Article
  • [Publication-country] United States
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22. Chan AO, Rashid A: CpG island methylation in precursors of gastrointestinal malignancies. Curr Mol Med; 2006 Jun;6(4):401-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • It is widely accepted that cancer evolves through several stepwise morphological stages such as the adenoma-carcinoma and hyperplastic polyp-serrated adenoma-carcinoma sequences in colorectal cancers, and the metaplasia-dysplasia-carcinoma sequences in esophageal and gastric cancers.
  • Inflammatory conditions of the gastrointestinal and pancreaticobiliary tracts and liver such as Barrett esophagus, Helicobacter pylori gastritis, inflammatory bowel disease and viral hepatitis, are associated with increased frequency of malignancies and CpG methylation.

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  • (PMID = 16900663.001).
  • [ISSN] 1566-5240
  • [Journal-full-title] Current molecular medicine
  • [ISO-abbreviation] Curr. Mol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 143
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23. Kong J, Nakagawa H, Isariyawongse BK, Funakoshi S, Silberg DG, Rustgi AK, Lynch JP: Induction of intestinalization in human esophageal keratinocytes is a multistep process. Carcinogenesis; 2009 Jan;30(1):122-30
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  • [Title] Induction of intestinalization in human esophageal keratinocytes is a multistep process.
  • Barrett's esophagus (BE) is the replacement of normal squamous esophageal mucosa with an intestinalized columnar epithelium.
  • Retroviral-mediated Cdx2 expression in immortalized human esophageal keratinocytes [EPC-human telomerase reverse transcriptase (hTERT)] could transiently be established but not maintained and was associated with a reduction in cell proliferation.
  • Two of these, SLC26a3/DRA (downregulated in adenoma) and Na+/H+ exchanger 2 (NHE2), were not previously known to be elevated in BE; however, we confirmed their elevation in BE tissue samples.
  • We conclude that ectopic proliferation signals, alterations in epigenetic gene regulation and the inhibition of tumor suppressor mechanisms are required for Cdx2-mediated intestinalization of human esophageal keratinocytes in BE.

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  • (PMID = 18845559.001).
  • [ISSN] 1460-2180
  • [Journal-full-title] Carcinogenesis
  • [ISO-abbreviation] Carcinogenesis
  • [Language] ENG
  • [Grant] United States / NIDDK NIH HHS / DK / R01 DK068366; United States / NCI NIH HHS / CA / P01 CA098101; United States / NIDDK NIH HHS / DK / P30 DK50306
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / CDX2 protein, human; 0 / Chromatin; 0 / Homeodomain Proteins; 136601-57-5 / Cyclin D1; M801H13NRU / Azacitidine
  • [Other-IDs] NLM/ PMC2722140
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24. Gerhard R, Nonogaki S, Fregnani JH, Soares FA, Nagai MA: NDRG1 protein overexpression in malignant thyroid neoplasms. Clinics (Sao Paulo); 2010 Jun;65(8):757-62
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  • METHODS: A tissue microarray paraffin block containing 265 tissue fragments corresponding to normal thyroid, nodular goiter, follicular adenoma, papillary thyroid carcinoma (classical pattern and follicular variant), follicular carcinoma, and metastases of papillary and follicular thyroid carcinomas were analyzed by immunohistochemistry using a polyclonal anti- N-myc downstream-regulated gene 1 antibody.
  • [MeSH-major] Adenoma / metabolism. Cell Cycle Proteins / metabolism. Intracellular Signaling Peptides and Proteins / metabolism. Neoplasm Proteins / metabolism. Thyroid Neoplasms / metabolism

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  • (PMID = 20835551.001).
  • [ISSN] 1980-5322
  • [Journal-full-title] Clinics (São Paulo, Brazil)
  • [ISO-abbreviation] Clinics (Sao Paulo)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
  • [Chemical-registry-number] 0 / Cell Cycle Proteins; 0 / Intracellular Signaling Peptides and Proteins; 0 / N-myc downstream-regulated gene 1 protein; 0 / Neoplasm Proteins; Thyroid cancer, papillary
  • [Other-IDs] NLM/ PMC2933120
  • [Keywords] NOTNLM ; Immunohistochemistry / NDRG1 / Thyroid Carcinoma / Thyroid Gland / Tissue Microarray
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25. Becker L, Huang Q, Mashimo H: Immunostaining of Lgr5, an intestinal stem cell marker, in normal and premalignant human gastrointestinal tissue. ScientificWorldJournal; 2008 Nov 23;8:1168-76
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Using standard immunostaining, we compared expression of Lgr5 in normal colon and small intestine vs. small intestinal and colonic adenomas and Barrett's esophagus.
  • [MeSH-minor] AC133 Antigen. Adenoma / metabolism. Antigens, CD / metabolism. Biomarkers / metabolism. Glycoproteins / metabolism. Humans. Immunohistochemistry. Peptides / metabolism

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  • (PMID = 19030762.001).
  • [ISSN] 1537-744X
  • [Journal-full-title] TheScientificWorldJournal
  • [ISO-abbreviation] ScientificWorldJournal
  • [Language] eng
  • [Grant] United States / BLRD VA / BX / I01 BX000663; United States / NIDDK NIH HHS / DK / T32 DK 07760
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / AC133 Antigen; 0 / Antigens, CD; 0 / Biomarkers; 0 / Glycoproteins; 0 / LGR5 protein, human; 0 / PROM1 protein, human; 0 / Peptides; 0 / Prom1 protein, mouse; 0 / Receptors, G-Protein-Coupled
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26. Yamamoto H: Endoscopic submucosal dissection of early cancers and large flat adenomas. Clin Gastroenterol Hepatol; 2005 Jul;3(7 Suppl 1):S74-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • By using ESD with sodium hyaluronate and an ST hood, it is feasible to treat endoscopically large superficial tumors in the stomach, esophagus, and colon, which used to require surgical treatments.
  • [MeSH-major] Adenoma / surgery. Endoscopy, Gastrointestinal / methods. Gastrointestinal Neoplasms / surgery. Intestinal Mucosa / surgery

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  • (PMID = 16013004.001).
  • [ISSN] 1542-3565
  • [Journal-full-title] Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • [ISO-abbreviation] Clin. Gastroenterol. Hepatol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 5
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27. Hohmann J, Loddenkemper C, Albrecht T: Assessment of a biliary hamartoma with contrast-enhanced sonography using two different contrast agents. Ultraschall Med; 2009 Apr;30(2):185-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A 49 year old male with carcinoma of the esophagus was staged using conventional US of the abdomen.
  • [MeSH-major] Adenoma, Bile Duct / ultrasonography. Bile Duct Diseases / ultrasonography. Bile Duct Neoplasms / ultrasonography. Bile Ducts, Intrahepatic / ultrasonography. Contrast Media. Hamartoma / ultrasonography. Phospholipids. Polysaccharides. Sulfur Hexafluoride. Ultrasonography, Doppler, Duplex
  • [MeSH-minor] Biopsy, Fine-Needle. Diagnosis, Differential. Esophageal Neoplasms / pathology. Esophageal Neoplasms / ultrasonography. Humans. Incidental Findings. Liver Neoplasms / pathology. Liver Neoplasms / secondary. Liver Neoplasms / ultrasonography. Male. Middle Aged. Neoplasm Staging. Sensitivity and Specificity

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  • (PMID = 18726842.001).
  • [ISSN] 1438-8782
  • [Journal-full-title] Ultraschall in der Medizin (Stuttgart, Germany : 1980)
  • [ISO-abbreviation] Ultraschall Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Phospholipids; 0 / Polysaccharides; 0 / contrast agent BR1; 127279-08-7 / SHU 508; WS7LR3I1D6 / Sulfur Hexafluoride
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28. Patel KN, Shaha AR: Locally advanced thyroid cancer. Curr Opin Otolaryngol Head Neck Surg; 2005 Apr;13(2):112-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Carcinoma, Papillary, Follicular / pathology. Thyroid Neoplasms / pathology
  • [MeSH-minor] Esophagus / pathology. Humans. Muscle, Skeletal / pathology. Neoplasm Recurrence, Local. Pharynx / pathology. Positron-Emission Tomography. Recurrent Laryngeal Nerve / pathology. Recurrent Laryngeal Nerve / surgery. Thyroidectomy. Trachea / pathology

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  • (PMID = 15761287.001).
  • [ISSN] 1068-9508
  • [Journal-full-title] Current opinion in otolaryngology & head and neck surgery
  • [ISO-abbreviation] Curr Opin Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 34
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29. Singh A, Pandey KC, Pant NK: Cavitary mucoepidermoid carcinoma of lung with metastases in skeletal muscles as presenting features: a case report and review of the literature. J Cancer Res Ther; 2010 Jul-Sep;6(3):350-2
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  • Later studies showed that they can arise as a primary in bronchus, esophagus, lacrimal glands, pancreas, thymus and thyroid gland.
  • Initially described as a benign adenoma, it is now considered to be a malignant epithelial tumor.
  • [MeSH-major] Carcinoma, Mucoepidermoid / diagnosis. Lung Neoplasms / diagnosis. Muscle Neoplasms / secondary. Muscle, Skeletal / pathology

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  • (PMID = 21119274.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] India
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30. Bajbouj M, von Weyhern C, Becker V, Seidl S, Ott R, Schatke W, Fend F, Schmid RM, Meining A: True adenomas of the cardia: a case series of 3 patients. Digestion; 2008;77(1):65-7
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  • METHODS AND RESULTS: Three patients with polypoid masses at the cardia below the Z-line were submitted to a tertiary referral center for further diagnosis and therapy.
  • In 2 of the 3 cases Barrett's esophagus with low-grade intraepithelial neoplasia was assumed on the basis of histopathological examination of biopsy specimens taken from the surface of the lesions.
  • In 2 of the 3 cases the final histopathological diagnosis of low-grade adenoma of the cardia could only be established after complete removal of the polypoid masses.
  • CONCLUSIONS: Adenomas of the cardia can be mistaken for dysplasia arising from Barrett's esophagus, if the diagnosis is based on endoscopic biopsies only.

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  • [Copyright] Copyright 2008 S. Karger AG, Basel.
  • (PMID = 18349540.001).
  • [ISSN] 1421-9867
  • [Journal-full-title] Digestion
  • [ISO-abbreviation] Digestion
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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31. Lardinois D, Weder W, Roudas M, von Schulthess GK, Tutic M, Moch H, Stahel RA, Steinert HC: Etiology of solitary extrapulmonary positron emission tomography and computed tomography findings in patients with lung cancer. J Clin Oncol; 2005 Oct 1;23(28):6846-53
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A diagnosis was obtained in 69 of these patients, including 37 (54%) with solitary metastases and 32 (46%) with lesions unrelated to the lung primary.
  • The six malignancies consisted of carcinoma of the breast in two patients, and carcinoma of the orbit, esophagus, prostate, and non-Hodgkin's lymphoma in one patient each.
  • Benign tumors and inflammatory lesions included eight colon adenomas, four Warthin's tumors, one granuloma of the lower jaw, one adenoma of the thyroid gland, one compensatory muscle activity due to vocal chord palsy, two occurrences of arthritis, three occurrences of reflux esophagitis, two occurrences of pancreatitis, two occurrences of diverticulitis, one hemorrhoidal inflammation, and one rib fracture.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Diagnosis, Differential. Female. Fluorodeoxyglucose F18. Humans. Inflammation. Male. Middle Aged. Neoplasm Staging. Prospective Studies. Radiopharmaceuticals. Sensitivity and Specificity. Tomography, X-Ray Computed

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  • (PMID = 16192576.001).
  • [ISSN] 0732-183X
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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32. Ge D, You Z: Expression of interleukin-17RC protein in normal human tissues. Int Arch Med; 2008;1(1):19
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  • RESULTS: IL-17RC expression in 51 normal human tissues and two benign tumors (i.e., lymphangioma and parathyroid adenoma) on the tissue microarrays was determined by immunohistochemical staining, using two polyclonal antibodies against IL-17RC.
  • IL-17RC protein was expressed in many cell types including the myocardial cells, vascular and lymphatic endothelial cells, glandular cells (of the adrenal, parathyroid, pituitary, thyroid, pancreas, parotid salivary, and subepidermal glands), epithelial cells (of the esophagus, stomach, intestine, anus, renal tubule, breast, cervix, Fallopian tube, epididymis, seminal vesicle, prostate, gallbladder, bronchus, lung, and skin), oocytes in the ovary, Sertoli cells in the testis, motor neurons in the spinal cord, autonomic ganglia and nerves in the intestine, skeletal muscle cells, adipocytes, articular chondrocytes, and synovial cells.

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  • (PMID = 18928529.001).
  • [ISSN] 1755-7682
  • [Journal-full-title] International archives of medicine
  • [ISO-abbreviation] Int Arch Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2596096
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33. Taniguchi H, Yamamoto H, Hirata T, Miyamoto N, Oki M, Nosho K, Adachi Y, Endo T, Imai K, Shinomura Y: Frequent epigenetic inactivation of Wnt inhibitory factor-1 in human gastrointestinal cancers. Oncogene; 2005 Nov 24;24(53):7946-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • By using RT-PCR, bisulfite sequence analysis, and methylation-specific PCR, we analysed expression and methylation of WIF-1 in cancer cell lines and freshly resected cancer tissues of the esophagus, stomach, colorectum, and pancreas.
  • Downregulation of WIF-1 mRNA expression was observed in 61 (91.0%) of 67 cancer cell lines, 16 (80.0%) of 20 esophageal, 23 (74.2%) of 31 gastric, 41 (82.0%) of 50 colorectal, and six (75.0%) of eight pancreatic cancer tissues.
  • Indeed, downregulation of WIF-1 expression was observed in 32 (72.7%) of 44 colorectal adenoma tissues and 18 (78.2%) of 23 early mucosal or submucosal colorectal carcinoma tissues.
  • Transfection of the WIF-1 gene construct into TE-1 esophageal cancer cell lines or SW48 colon cancer cell lines lacking WIF-1 expression resulted in a significant inhibition on colony formation, cell proliferation, anchorage-independent growth in soft agar.

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  • (PMID = 16007117.001).
  • [ISSN] 0950-9232
  • [Journal-full-title] Oncogene
  • [ISO-abbreviation] Oncogene
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Adaptor Proteins, Signal Transducing; 0 / Carrier Proteins; 0 / Repressor Proteins; 0 / WIF1 protein, human
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34. Wheeler YY, Stoll LM, Sheth S, Li QK: Metastatic signet ring cell carcinoma presenting as a thyroid nodule: report of a case with fine-needle aspiration cytology. Diagn Cytopathol; 2010 Aug;38(8):597-602
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • These cytological features may be seen in cases of papillary thyroid carcinoma or signet ring cell follicular adenoma; however, the presence of the signet ring cells is unusual in primary thyroid lesions and raises the possibility of a metastatic lesion to the thyroid.
  • The patient was also found to have a 3.7-cm mass in the distal esophagus/proximal stomach.
  • The purpose of our study is to discuss the cytological features and the differential diagnosis of this unusual thyroid FNA case.

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  • [Copyright] 2009 Wiley-Liss, Inc.
  • (PMID = 20014306.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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35. Thrumurthy SG, Date RS, Mughal MM, Pursnani KG, Ward JB: The surgical management of pancreaticoduodenal tumours in multiple endocrine neoplasia type 1. BMJ Case Rep; 2009;2009

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Upon investigation, he was found to have renal stone disease secondary to a parathyroid adenoma.
  • Further tests revealed high pituitary hormone and gastrin values, confirming the diagnosis of multiple endocrine neoplasia type 1 (MEN 1) and Zollinger-Ellison syndrome.

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  • (PMID = 21686642.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
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36. Cayo A, Chen H: Radioguided reoperative parathyroidectomy for persistent primary hyperparathyroidism. Clin Nucl Med; 2008 Oct;33(10):668-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Repeat Tc-99m sestamibi parathyroid scan showed an inferior right parathyroid adenoma.
  • With the intraoperative guidance of a hand-held gamma probe, an enlarged parathyroid gland was localized on the spine behind the esophagus on the right, and successfully removed.

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  • (PMID = 18806564.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
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37. Jankowski J, Hunt R: Cyclooxygenase-2 inhibitors in colorectal cancer prevention: counterpoint. Cancer Epidemiol Biomarkers Prev; 2008 Aug;17(8):1858-61
Hazardous Substances Data Bank. ACETYLSALICYLIC ACID .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The cyclooxygenase-2 selective agents (COXIBS) have an efficacy similar to that of aspirin for most gastrointestinal (GI) lesions but not esophagus.
  • Specifically, there are beneficial short term effects of COXIBs on the risk of colorectal adenoma as shown in the Approve, PreSAP, and APC studies.
  • The value of aspirin remains with respect for efficacy, mainly in the esophagus, and the side effect profile, especially in the elderly if given with acid suppression therapy.

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  • (PMID = 18708372.001).
  • [ISSN] 1055-9965
  • [Journal-full-title] Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
  • [ISO-abbreviation] Cancer Epidemiol. Biomarkers Prev.
  • [Language] ENG
  • [Grant] United Kingdom / Cancer Research UK / / 4584; United Kingdom / Cancer Research UK / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cyclooxygenase 2 Inhibitors; 0 / Proton Pump Inhibitors; R16CO5Y76E / Aspirin
  • [Number-of-references] 46
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38. Bando H, Ikematsu H, Fu KI, Oono Y, Kojima T, Minashi K, Yano T, Matsuda T, Saito Y, Kaneko K, Ohtsu A: A laterally-spreading tumor in a colonic interposition treated by endoscopic submucosal dissection. World J Gastroenterol; 2010 Jan 21;16(3):392-4
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  • Herein we describe an early colonic carcinoma which developed in a colonic interposition 14 years after surgery for esophageal cancer, which was successfully treated by endoscopic submucosal dissection (ESD).
  • An 80-year-old man underwent colonic interposition between the upper esophagus and stomach after surgery for an early esophageal squamous cell carcinoma in 1994.
  • Histologically, the lesion was an intramucosal moderately differentiated adenocarcinoma in a tubular adenoma.

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  • (PMID = 20082488.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] China
  • [Number-of-references] 16
  • [Other-IDs] NLM/ PMC2807963
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39. Little SG, Rice TW, Bybel B, Mason DP, Murthy SC, Falk GW, Rybicki LA, Blackstone EH: Is FDG-PET indicated for superficial esophageal cancer? Eur J Cardiothorac Surg; 2007 May;31(5):791-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Is FDG-PET indicated for superficial esophageal cancer?
  • METHODS: Fifty-eight superficial esophageal cancer patients had preoperative positron emission tomography, 53 (91%) fused with computed tomography.
  • Positron emission tomography detected three (5%) distant hypermetabolic sites, all synchronous tumors (papillary thyroid cancer, adrenal pheochromocytoma, rectal adenoma).
  • CONCLUSIONS: Because positron emission tomography can neither differentiate pTis from T1 nor classify T, N, and M, it is not indicated in staging superficial esophageal cancer.
  • [MeSH-major] Adenocarcinoma / radionuclide imaging. Esophageal Neoplasms / radionuclide imaging. Neoplasm Staging / methods. Positron-Emission Tomography / methods
  • [MeSH-minor] Diagnosis, Differential. Esophagoscopy / methods. Esophagus / pathology. Esophagus / radionuclide imaging. Fluorine Radioisotopes. Fluorodeoxyglucose F18 / pharmacokinetics. Humans. Neoplasm Metastasis / radionuclide imaging. Radiopharmaceuticals

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  • (PMID = 17337344.001).
  • [ISSN] 1010-7940
  • [Journal-full-title] European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • [ISO-abbreviation] Eur J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Fluorine Radioisotopes; 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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40. Singhi AD, Montgomery EA: Colorectal granular cell tumor: a clinicopathologic study of 26 cases. Am J Surg Pathol; 2010 Aug;34(8):1186-92
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  • Granular cell tumor (GCT) is commonly located in the subcutaneous tissue and oral cavity, and uncommon in the gastrointestinal tract, in which the majority arises in the esophagus with over-representation in African Americans (AA).
  • Some had reactive mucosal surface changes (7/20, 35%), including 1 initially misdiagnosed as a tubular adenoma.

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  • (PMID = 20661017.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / S100 Proteins
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41. Honda T, Yamamoto H, Osawa H, Yoshizawa M, Nakano H, Sunada K, Hanatsuka K, Sugano K: Endoscopic submucosal dissection for superficial duodenal neoplasms. Dig Endosc; 2009 Oct;21(4):270-4
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  • In our hospital, ESD has been used concurrently in other parts of the gastrointestinal tract, including the esophagus and colorectum from the beginning of its development.
  • [MeSH-major] Adenoma / surgery. Carcinoma / surgery. Dissection / methods. Duodenal Neoplasms / surgery. Endoscopy. Intestinal Mucosa / surgery

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  • (PMID = 19961529.001).
  • [ISSN] 1443-1661
  • [Journal-full-title] Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society
  • [ISO-abbreviation] Dig Endosc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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42. Darling MR, Tsai S, Jackson-Boeters L, Daley TD, Diamandis EP: Human kallikrein 8 expression in salivary gland tumors. Head Neck Pathol; 2008 Sep;2(3):169-74
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  • The human kallikrein 8 protein (KLK8) is expressed in many normal tissues including esophagus, skin, testis, tonsil, kidney, breast, and salivary gland, and is found in biological fluids including breast milk, amniotic fluid, seminal fluid and serum.
  • [MeSH-major] Adenocarcinoma / metabolism. Adenoma, Pleomorphic / metabolism. Kallikreins / metabolism. Salivary Gland Neoplasms / metabolism. Salivary Glands, Minor / metabolism

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  • (PMID = 20614312.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 3.4.21.- / KLK8 protein, human; EC 3.4.21.- / Kallikreins
  • [Other-IDs] NLM/ PMC2807567
  • [Keywords] NOTNLM ; Human kallikrein 8 / Immunohistochemistry / Kallikreins / Prognostic markers / Salivary gland tumors
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43. Mountford C, Lean C, Malycha P, Russell P: Proton spectroscopy provides accurate pathology on biopsy and in vivo. J Magn Reson Imaging; 2006 Sep;24(3):459-77
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  • The first is in the pathology laboratory, where it can be an adjunct to, and in some cases replacement, for difficult pathologies like Barrett's esophagus and follicular adenoma of the thyroid.
  • The second application for spectroscopy is in vivo to provide a preoperative diagnosis and this is now achievable for several organs including the prostate.
  • The combination of in vivo MRI, in vivo MRS, and ex vivo MRS on biopsy samples offers a modality of very high accuracy for preoperative diagnosis and provision of prognostic information for human cancers.
  • [MeSH-major] Biopsy / methods. Magnetic Resonance Spectroscopy / methods. Neoplasms / diagnosis
  • [MeSH-minor] Adenocarcinoma / metabolism. Breast Neoplasms / diagnosis. Female. Humans. Magnetic Resonance Imaging / methods. Male. Prognosis. Reproducibility of Results. Thyroid Neoplasms / diagnosis. Uterine Cervical Neoplasms / diagnosis

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  • (PMID = 16897689.001).
  • [ISSN] 1053-1807
  • [Journal-full-title] Journal of magnetic resonance imaging : JMRI
  • [ISO-abbreviation] J Magn Reson Imaging
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 102
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44. Ramser KL, Sprabery LR, Hamann GL, George CM, Will A: Results of an intervention in an academic Internal Medicine Clinic to continue, step-down, or discontinue proton pump inhibitor therapy related to a tennessee medicaid formulary change. J Manag Care Pharm; 2009 May;15(4):344-50
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  • In order to obtain an approved PA for a PPI, the patient was required to have either (a) a diagnosis of erosive esophagitis, Barrett's esophagus, Schatzki's ring, a pathological hypersecretory condition (e.g., Zollinger-Ellison syndrome, multiple endocrine adenoma), grade III-IV gastroesophageal reflux disease (GERD), non-steroidal anti-inflammatory drug gastropathy, significant gastrointestinal bleed; or (b) another indication for acid suppression therapy (e.g., GERD, hyperacidity in cystic fibrosis, gastric or duodenal ulcer, gastroparesis) with a history of failure of prior therapy with a histamine-2 receptor antagonist (H2-blocker).

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  • (PMID = 19422274.001).
  • [ISSN] 1083-4087
  • [Journal-full-title] Journal of managed care pharmacy : JMCP
  • [ISO-abbreviation] J Manag Care Pharm
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Histamine H2 Antagonists; 0 / Proton Pump Inhibitors
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45. Rocha Ramírez JL, Villanueva Sáenz E, Hernández-Magro PM, Sierra Montenegro E, Soto Quirino R, Pérez Aguirre J, Blanco Lemus E: [Hereditary mixed polyposis syndrome. First report in Mexico]. Rev Gastroenterol Mex; 2005 Oct-Dec;70(4):430-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • At blood test with hemoglobin of 9.7 g/dL, and colonoscopy with multiple polyps within colon and rectum, upper endoscopy with a big esophageal polyp and multiple polyps in gastric and duodenal lining smaller than 1 cm.
  • Histopathologic study of the polyps report mixed pattern of polyps: (hyperplasic-adenomatous, juvenile-adenomatous, adenoma-inflammatory-hyperplasic, hyperplasic-adenomatous with a high degree dysplasia); juvenile in esophagus, and hyperplasic in stomach and duodenum.
  • Patient was undergone to totalproctocolectomy and reconstruction by "J" ileoanal pouch with good outcome, and endoscopic esophageal polypectomy, with actual surveillance.
  • [MeSH-major] Adenomatous Polyposis Coli / diagnosis

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  • (PMID = 17058983.001).
  • [ISSN] 0375-0906
  • [Journal-full-title] Revista de gastroenterología de México
  • [ISO-abbreviation] Rev Gastroenterol Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
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46. Fang SY, Wu CY, Chen HC, Lin YC, Wang YY, Fang HY: Giant adenoma arising in the lower esophagus with adenocarcinoma. Dig Dis Sci; 2007 Nov;52(11):3181-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant adenoma arising in the lower esophagus with adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma / pathology. Esophageal Neoplasms / pathology. Neoplasms, Multiple Primary / pathology
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Endoscopy, Gastrointestinal. Esophagectomy / methods. Follow-Up Studies. Gastrectomy / methods. Humans. Jejunostomy / methods. Lymph Node Excision. Male. Mediastinum

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  • (PMID = 17410429.001).
  • [ISSN] 0163-2116
  • [Journal-full-title] Digestive diseases and sciences
  • [ISO-abbreviation] Dig. Dis. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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47. Yoon JK, Remer EM, Herts BR: Incidental pheochromocytoma mimicking adrenal adenoma because of rapid contrast enhancement loss. AJR Am J Roentgenol; 2006 Nov;187(5):1309-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Incidental pheochromocytoma mimicking adrenal adenoma because of rapid contrast enhancement loss.
  • [MeSH-major] Adenoma / radiography. Adrenal Gland Neoplasms / radiography. Contrast Media. Incidental Findings. Pheochromocytoma / radiography. Tomography, X-Ray Computed
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / etiology. Barrett Esophagus / complications. Diagnosis, Differential. Esophageal Neoplasms / diagnosis. Esophageal Neoplasms / etiology. Fluorodeoxyglucose F18. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Positron-Emission Tomography. Radiopharmaceuticals

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  • (PMID = 17056921.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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48. Sträter J, Wiesmüller C, Perner S, Kuefer R, Möller P: Alpha-methylacyl-CoA racemase (AMACR) immunohistochemistry in Barrett's and colorectal mucosa: only significant overexpression favours a diagnosis of intraepithelial neoplasia. Histopathology; 2008 Feb;52(3):399-402
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  • [Title] Alpha-methylacyl-CoA racemase (AMACR) immunohistochemistry in Barrett's and colorectal mucosa: only significant overexpression favours a diagnosis of intraepithelial neoplasia.
  • [MeSH-major] Barrett Esophagus / enzymology. Carcinoma in Situ / enzymology. Colorectal Neoplasms / enzymology. Intestinal Mucosa / enzymology. Racemases and Epimerases / metabolism
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / enzymology. Adenoma / diagnosis. Adenoma / enzymology. Biomarkers, Tumor / metabolism. Colitis, Ulcerative / diagnosis. Colitis, Ulcerative / enzymology. Diagnosis, Differential. Humans. Immunohistochemistry

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  • (PMID = 18081815.001).
  • [ISSN] 1365-2559
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Letter
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 5.1.- / Racemases and Epimerases; EC 5.1.99.4 / alpha-methylacyl-CoA racemase
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49. Kia L, Sikka SK, Komanduri S: An unusual case of malignant dysphagia after colonic interposition treated with endoscopic mucosal resection. Gastrointest Endosc; 2010 Dec;72(6):1320-1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma / surgery. Adenoma / diagnosis. Adenoma / surgery. Colon / transplantation. Colonic Polyps / diagnosis. Colonic Polyps / surgery. Deglutition Disorders / diagnosis. Deglutition Disorders / surgery. Endoscopy, Digestive System. Esophageal Neoplasms / diagnosis. Esophageal Neoplasms / surgery. Esophageal Stenosis / diagnosis. Esophageal Stenosis / surgery. Esophagectomy. Neoplasms, Second Primary / diagnosis. Neoplasms, Second Primary / surgery. Postoperative Complications / diagnosis. Postoperative Complications / surgery
  • [MeSH-minor] Aged. Cell Transformation, Neoplastic / pathology. Electrocoagulation. Esophagus / pathology. Esophagus / surgery. Humans. Intestinal Mucosa / pathology. Intestinal Mucosa / surgery. Male. Neoplasm Invasiveness. Reoperation


50. Cohen J: Optical contrast endoscopy: is it ready for routine use? Gastroenterology; 2009 Jan;136(1):52-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adenoma / diagnosis. Barrett Esophagus / diagnosis. Biopsy. Colonic Neoplasms / diagnosis. Colonic Polyps / pathology. Esophagus / pathology. Humans. Image Enhancement. Inflammatory Bowel Diseases / diagnosis. Stomach Neoplasms / pathology

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  • (PMID = 19063888.001).
  • [ISSN] 1528-0012
  • [Journal-full-title] Gastroenterology
  • [ISO-abbreviation] Gastroenterology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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