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Items 1 to 100 of about 11029
1. Greven WL, van Bemmel T: Rare oxygen, a rare way to diagnose Conn's syndrome. NDT Plus; 2008 Dec;1(6):427-428

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We present a case of a patient with symptoms of mountain sickness at relatively low altitudes, who appeared to have Conn's syndrome (primary hyperaldosteronism). <b>Case.
  • A CT scan of the abdomen revealed an adenoma in the left adrenal gland.

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  • (PMID = 28657013.001).
  • [ISSN] 1753-0784
  • [Journal-full-title] NDT plus
  • [ISO-abbreviation] NDT Plus
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; Conn's syndrome / hyperaldosteronism / mountain sickness
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2. Rabeneck L, Paszat LF: Circumstances in which colonoscopy misses cancer. Frontline Gastroenterol; 2010 Apr;1(1):52-58

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Caecal intubation and adenoma detection rates should be reported and reviewed.

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  • (PMID = 28839544.001).
  • [ISSN] 2041-4137
  • [Journal-full-title] Frontline gastroenterology
  • [ISO-abbreviation] Frontline Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
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3. Krutsay M, Chanis W: [Retroperitoneal adenoma]. Magy Onkol; 2007;51(1):63-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Retroperitoneal adenoma].
  • [Transliterated title] Retroperitonealis adenoma.
  • The authors describe a tumor localized next to the left adrenal gland.
  • On histological examination the lipid-rich tumor was found to be partly a solid adrenocortical adenoma and partly a tubular oncocytoma.
  • [MeSH-major] Adenoma / diagnosis. Adenoma, Oxyphilic / diagnosis. Adrenal Cortex Neoplasms / diagnosis. Retroperitoneal Neoplasms / diagnosis

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  • (PMID = 17417677.001).
  • [ISSN] 0025-0244
  • [Journal-full-title] Magyar onkologia
  • [ISO-abbreviation] Magy Onkol
  • [Language] hun
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Hungary
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4. Picozzi P, Losa M, Mortini P, Valle MA, Franzin A, Attuati L, da Passano CF, Giovanelli M: Radiosurgery and the prevention of regrowth of incompletely removed nonfunctioning pituitary adenomas. J Neurosurg; 2005 Jan;102(s_supplement):71-74

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radiosurgery and the prevention of regrowth of incompletely removed nonfunctioning pituitary adenomas.
  • OBJECT: The authors studied the efficacy of gamma knife radiosurgery (GKS) in the prevention of regrowth of nonfunctioning pituitary adenomas (NPA).
  • All patients had undergone surgery in our department and recurrent or residual adenoma was demonstrated on postoperative MR imaging.
  • In Group B the mean margin dose was 16.5 ± 0.3 Gy (range 13-21 Gy).
  • In Group B patients, tumor volume decreased from a baseline value of 2.4 ± 0.2 cm<sup>3</sup> to 1.6 ± 0.2 cm<sup>3</sup> at last follow up (p < 0.001).
  • Thus, GKS is recommended after microsurgery when visible tumor can be detected on imaging studies.

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  • (PMID = 28306434.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; gamma knife surgery / nonfunctioning pituitary adenoma / pituitary
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5. Killory BD, Kresl JJ, Wait SD, Ponce FA, Porter R, White WL: Hypofractionated Cyberknife Radiosurgery for Perichiasmatic Pituitary Adenomas: Early Results. Neurosurgery; 2009 Feb 01;64(suppl_2):A19-A25

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hypofractionated Cyberknife Radiosurgery for Perichiasmatic Pituitary Adenomas: Early Results.

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  • (PMID = 28175597.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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6. Monjero-Ares I, Gegundez-Gómez C, Couselo-Villanueva JM, Moreda-Pérez M, Jorge-Iglesias M, Torres-García I, Alvarez-Gutiérrez AE, Arija-Val JF: [Association of pheochromocytoma with contralateral nonfunctioning adrenal adenoma]. Cir Esp; 2006 Feb;79(2):126-8
MedlinePlus Health Information. consumer health - Pheochromocytoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Association of pheochromocytoma with contralateral nonfunctioning adrenal adenoma].
  • [Transliterated title] Asociación de feocromocitoma con adenoma suprarrenal contralateral no funcionante.
  • A 52-year-old woman complaining of abdominal pain, headaches and palpitations was admitted to our hospital for investigation of a bilateral adrenal tumor.
  • The definitive diagnosis was right pheochromocytoma and left adrenocortical adenoma.
  • Only four cases of pheochromocytoma associated with nonfunctioning adrenal adenoma have previously been reported.
  • [MeSH-major] Adenoma. Adrenal Gland Neoplasms. Neoplasms, Multiple Primary. Pheochromocytoma

  • Genetic Alliance. consumer health - Pheochromocytoma.
  • MedlinePlus Health Information. consumer health - Adrenal Gland Cancer.
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  • (PMID = 16539953.001).
  • [ISSN] 0009-739X
  • [Journal-full-title] Cirugía española
  • [ISO-abbreviation] Cir Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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7. Alcalá-Galiano A, Borruel Nacenta S, Jiménez-Arranz S, Martín-Medina P: [Serous oligocystic adenoma of the pancreas]. Radiologia; 2007 Nov-Dec;49(6):427-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Serous oligocystic adenoma of the pancreas].
  • [Transliterated title] Adenoma seroso oligoquístico del páncreas.
  • Serous oligocystic or macrocystic adenoma of the pancreas is a very uncommon morphological variant of what was classically termed microcystic adenoma of the pancreas.
  • This is a benign neoplasm; however, its radiological appearance mimicks that of potentially malignant mucinous neoplasms of the pancreas.
  • [MeSH-major] Adenoma / radiography. Pancreatic Neoplasms / radiography

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  • (PMID = 18021674.001).
  • [ISSN] 0033-8338
  • [Journal-full-title] Radiología
  • [ISO-abbreviation] Radiologia
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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8. Medina EA, Arias VL: [Middle ear adenoma]. Biomedica; 2009 Sep;29(3):348-53

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Middle ear adenoma].
  • [Transliterated title] Adenoma del oído medio.
  • Herein, a middle ear neoplasm is described that became apparent because of its appearance in the external ear duct as it protruded from the middle ear through the eardrum.
  • Following resection, the specimen was determined to be a benign epithelial tumor.
  • Absence of adequate clinical information complicated the diagnosis; therefore,histochemistry and immunohistochemistry analyses were necessary to reach the final diagnosis of middle ear adenoma.
  • [MeSH-major] Adenoma. Ear Neoplasms. Ear, Middle

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  • (PMID = 20436986.001).
  • [ISSN] 0120-4157
  • [Journal-full-title] Biomédica : revista del Instituto Nacional de Salud
  • [ISO-abbreviation] Biomedica
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Colombia
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9. Pollock BE: Radiotherapy and Radiosurgery for Hormone Secreting Pituitary Adenomas. Neurosurgery; 2010 May 01;66(5):E1030

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Radiotherapy and Radiosurgery for Hormone Secreting Pituitary Adenomas.

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  • (PMID = 28173407.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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10. Holten-Andersen MN, Brunner N, Nielsen HJ, Christensen IJ, Moller Sorensen N, Schrol Rasmussen AS, Primdahl H, Orntoft T: Levels of tissue inhibitor of metalloproteinases 1 in plasma and urine from patients with bladder cancer. Int J Biol Markers; 2006 Jan - Mar;21(1):6-11

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: TIMP-1 levels were determined in urine and plasma from healthy donors (n=26), patients with bacterial bladder infection (n=24), urothelial bladder adenoma (n=3) or adenocarcinoma (n=7).
  • CONCLUSION: Our previous observation of a weak but significant correlation between plasma TIMP-1 and age was confirmed.

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  • (PMID = 28207096.001).
  • [ISSN] 1724-6008
  • [Journal-full-title] The International journal of biological markers
  • [ISO-abbreviation] Int. J. Biol. Markers
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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11. Tlachacova D, Schmitt M, Novotny J Jr, Novotny J, Majali M, Liscak R: A comparison of the gamma knife model C and the Automatic Positioning System with Leksell model B. J Neurosurg; 2005 Jan;102(s_supplement):25-28
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Data were obtained in 463 patients treated with the B model and 518 patients treated with the C model.
  • Data were analyzed in patients in whom the following diagnoses had been made: vestibular schwannoma, pituitary adenoma, meningioma, solitary metastasis, and other benign and malignant solitary tumors.
  • CONCLUSIONS: With the C model there was a better conformity for most treated targets, such as vestibular schwannomas (p = 0.005) and meningiomas (p = 0.015).
  • The mean time saved using the C model with the APS was 41 minutes per treatment.

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  • (PMID = 28306471.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; conformity index / extracranial exposure / staff exposure / stereotactic radiosurgery
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12. Harriss DJ, Cable NT, George K, Reilly T, Renehan AG, Haboubi N: Physical Activity Before and After Diagnosis of Colorectal Cancer : Disease Risk, Clinical Outcomes, Response Pathways and Biomarkers. Sports Med; 2007 Nov;37(11):947-960

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Physical Activity Before and After Diagnosis of Colorectal Cancer : Disease Risk, Clinical Outcomes, Response Pathways and Biomarkers.
  • Epidemiological evidence shows an association between occupational and recreational physical activity and colon cancer, but has not established whether physical activity is protective against low-risk or more advanced adenomas.
  • There is little available evidence for the benefits of physical activity before diagnosis of colorectal cancer for disease-specific survival and prognosis, and the clinical effects of an exercise intervention after diagnosis have not been investigated.
  • Markers/mechanisms by which physical activity may protect against colorectal cancer and/or improve disease prognosis include gastrointestinal transit-time, chronic inflammation, immune function, insulin levels, insulin-like growth factors, genetics and obesity.

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  • (PMID = 28224408.001).
  • [ISSN] 1179-2035
  • [Journal-full-title] Sports medicine (Auckland, N.Z.)
  • [ISO-abbreviation] Sports Med
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] New Zealand
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13. Darling MR, Jackson-Boeters L, Daley TD, Diamandis EP: [Human kallikrein 13 expression in salivary gland tumors]. Int J Biol Markers; 2006 Apr-Jun;21(2):106-110

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Human kallikrein 13 expression in salivary gland tumors].
  • Petraki et al have previously described presence of hK13 in salivary gland tissue, localized to duct epithelia and some acinar cells.
  • The aim of this study was to determine whether hK13 is expressed in salivary gland tissues and salivary gland tumors (both benign and malignant), in order to compare normal with tumor tissues.
  • Pleomorphic adenomas (PA), adenoid cystic carcinomas (ACC), polymorphous low grade adenocarcinomas (PLGA), acinic cell carcinomas (ACI), mucoepidermoid carcinomas (MEC) and adenocarcinomas not otherwise specified (ANOS) of both minor and major salivary glands were examined.
  • The results of this study indicate that most salivary gland tumors show high levels of expression of hK13.
  • Overall, staining in PA was significantly less than that seen in normal salivary gland tissue.
  • PLGA, ACC and ANOS each stained significantly more than normal salivary gland tissue while MEC and ACI did not.
  • In conclusion, we demonstrate the high expression of hK13 in several common salivary gland tumors.

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  • (PMID = 28207129.001).
  • [ISSN] 1724-6008
  • [Journal-full-title] The International journal of biological markers
  • [ISO-abbreviation] Int. J. Biol. Markers
  • [Language] ita
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Italy
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14. Kelly DF, Fatemi N, Dusick J: Pituitary Hormonal Loss and Recovery After Transsphenoidal Adenoma Removal. Neurosurgery; 2010 Jul 01;67(1):E221

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pituitary Hormonal Loss and Recovery After Transsphenoidal Adenoma Removal.

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  • (PMID = 28173413.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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15. Azuara D, Rodriguez-Moranta F, Soriano-Izquierdo A, Guardiola J, de Oca J, Biondo S, Blanco I, Esteller M, Capella G: Evaluation of stool melting curve analysis of methylated CpG island promoters as an alternative for early noninvasive diagnosis of colorectal tumors. J Clin Oncol; 2009 May 20;27(15_suppl):e15036

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : e15036 Background: Previous studies have shown that assessment of promoter hypermethylation of a limited number of genes in tumor biopsies may identify all colorectal tumors analyzed.
  • The aim of the present study was to assess the clinical usefulness of a panel of methylation biomarkers in stool DNA in the diagnosis of colorectal tumors using Methylation Curve (MC) analyses, a technique that simultaneously analyze all CpG residues within a promoter.
  • METHODS: Promoter methylation status of 5 tumor-related genes (RARB2, p16<sup>INK4a</sup>, MGMT, p14<sup>ARF</sup> and APC) was analyzed in DNA stool samples and corresponding tissues in an initial set of 12 newly diagnosed patients with primary colorectal carcinomas and 20 with colorectal adenomas using Methylation-specific PCR (MSP).
  • Results were validated in a set of 88 patients (20 healthy subjects, 17 inflammatory bowel disease, 23 adenomas, 28 carcinomas) using MC analyses.
  • RESULTS: In the initial set, the majority [10 of 12 (83%) carcinomas and 18 of 20 (90%) adenomas] of biopsies were positive for at least one marker.
  • In stool DNA prevalence was 75% for carcinomas (9 of 12) and 60% for adenomas (12 of 20) with no false positive in stools.
  • In the validation set MC analyses of biopsies showed that at least one marker was positive in 22 of 28 (79%) carcinomas and 16 of 23 (70%) adenomas.
  • In stool DNA, these percentages were 64% (18 of 28) for carcinomas and 42% (9 of 23) for adenomas.
  • CONCLUSIONS: Melting Curve analysis of a panel of methylation markers in stool DNA is a good alternative for the early non-invasive diagnosis of colorectal tumors.

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  • (PMID = 27964470.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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16. Morine Y, Shimada M, Imura S, Uchiyama H, Uchiyama H, Kanemura H, Arakawa Y, Hanaoka J, Sugimoto K: Clinical role of regulatory T cell in intraductal papillary mucinous neoplasms. J Clin Oncol; 2009 May 20;27(15_suppl):e15537

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : e15537 Background: Intraductal papillary mucinous neoplasms of pancreas (IPMNs) have malignant potential and exhibit a broad histologic spectrum, ranging from adenoma to invasive carcinoma.
  • Recently, several investigators have reported that regulatory T cells (Foxp3+CD4+ T cells including CD4+CD25+ T cells and CD4+CD25- T cells) play important roles in anti-tumor immunity.
  • Immunohistochemical expression of Foxp3 (abcam: FOXP3 antibody, 236A/E7), Fascin (Dako: Fascin antibody, 55K-2) and TGF-β (Santa Cruz: TGF-β1 antibody, SC146) in main tumor was assessed in all IPMN patients.

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  • (PMID = 27962313.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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17. Lai R Sr, Feng L, Liu L, Xie L, Wu X, Zhang S, Tang X, Geng J, Chen T: The clinical pathogensis significance associated with mutation of APC MCR in colorectal neoplasms. J Clin Oncol; 2009 May 20;27(15_suppl):e15119

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : e15119 Background: To explore the clinical pathogensis evalution of codon 1493,1367 and 1328 mutations in MCR (mutation cluster region) of exon 15 of APC (Adenomatous polyposis coli) gene in cases of colorectal neoplasm and the family history.
  • METHODS: The specimens from 21 colorectal adenoma specimens groups,16 colorectal carcinoma groups, 20 healthy germline groups with positive familial history and 8 healthy germline groups without familial history.
  • The allele mutations were checked out four genotypes such as 4478(G→A), 41/69(59.4%); 4478(G/A), 22/69(31.9%); 4096(C/T), 1/69 (1.4%) and 3979(C/T), 5/69(7.2%); but the significant groups status (P<0.05) were shown between the adenoma and nonfamily history group on the analysis of 4478(G→A) and (G/A), also the significant differences were tested between the with and without family history on the analysis of 4478(G→A).
  • CONCLUSIONS: In our data, the highest mutant frequency 4478(G→A) of 1493(ACG>ACA) presented to the significant phenotype of positive history and adenoma, but 4478 (G/A) were associated with colorectal adenocancer, which was discovered in the different effect to candidators despite the same synonymous mutation.

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  • (PMID = 27960846.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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18. Capella G, Castellsague E, Rennert G, Gruber S: APC allele-specific expression in carriers of Ashkenazi Jewish mutation I1307K. J Clin Oncol; 2009 May 20;27(15_suppl):e22181

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : e22181 Background: I1307K is a missense APC variant with incomplete penetrance that has been found in 6% of Jewish Ashkenazi population and confers a two-fold increased risk to develop multiple adenomas and colorectal tumours.
  • Tumor ASE correlated with the DNA mutant/wt allelic dose.
  • I1307K overexpression is not selected for during tumor progression.

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  • (PMID = 27963596.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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19. Obrador-Hevia A, Chin F, Gonzalez S, Vilardell F, Cordero D, Greenson J, Moreno V, Caldas C, Capella G: Wnt signaling somatic alterations in apc-associated fap adenomas. J Clin Oncol; 2009 May 20;27(15_suppl):e22046

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Wnt signaling somatic alterations in apc-associated fap adenomas.
  • METHODS: Sixty adenomas from FAP cases harboring pathogenic APC mutations were included (10 adenomas and 1 normal mucosa per case).
  • Somatic APC and KRAS alterations, β-catenin immunostaining and qRT-PCR of APC, MYC, AXIN2 and SFRP1 were analyzed. aCGH was also assessed in 26 FAP adenomas and 24 additional paired normal-adenoma-carcinoma samples.
  • RESULTS: A second APC alteration was present in 30 (50%) of adenomas (26 LOH and 4 point mutations).
  • In these cases diminished APC levels mRNA were observed in 11 of 30 adenomas analyzed..
  • In the remaining 3 cases APC mRNA was already underexpressed in normal mucosa with only 3 of 30 adenomas showing further underexpression.
  • All adenomas showed further MYC (logratio range: 1.78-2.92) and AXIN2 overexpression (logratio range: 1.62-4.65), corregulating with APC mRNA levels (r=0.31 for MYC; r=0.59 for AXIN2).
  • β-catenin nuclear immunostaining was detected in 80% of adenomas correlating with MYC mRNA levels.
  • While copy number changes were rare in adenomas (median number :2.5; range 0-5).

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  • (PMID = 27963228.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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20. Errata corrige. Int J Biol Markers; 2007 Jan-Mar;22(1):86

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The relative sensitivity for 7 cancers was 100% with OC and 67.9% with SENT, and for 48 high-risk adenomas (HRAs) it was 77.0% with OC and 66.6% with SENT.

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  • (PMID = 28207155.001).
  • [ISSN] 1724-6008
  • [Journal-full-title] The International journal of biological markers
  • [ISO-abbreviation] Int. J. Biol. Markers
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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21. Kannarkat GJ, Harris T, Kelly K, Fracasso P, Moskaluk C: Evaluation of plectin-1 immunohistochemical expression in human colon cancer tumor progression. J Clin Oncol; 2009 May 20;27(15_suppl):e22132

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Evaluation of plectin-1 immunohistochemical expression in human colon cancer tumor progression.
  • : e22132 Background: Plectin-1 (PLEC1), a known scaffolding protein, was recently discovered to be upregulated and redistributed to the cell membrane in multiple cancers, thereby providing a molecular imaging biomarker for disease detection.
  • The purpose of this study was to examine PLEC1 staining in the tumor progression of human colorectal carcinoma.
  • Colonic adenomas had a slightly higher mean IHC score, 2.57, with more cases falling in the intermediate group.
  • CONCLUSIONS: There is increasing membrane expression of PLEC1 in colonic epithelium through tumor progression.
  • The observation of a difference in IHC staining of normal and malignant tissue requires larger confirmatory studies, but the redistribution of PLEC1 to the cell surface is a potential biomarker for molecular imaging of cancer and potential target for novel therapeutic agents.
  • However, our finding of increased PLEC1 membrane staining in actively inflamed tissue may indicate an important caveat in the use and implementation of this biomarker in certain clinical situations.

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  • (PMID = 27963579.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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22. Sawasaki T, Katsube Y: The Ep-CAM: A potential candidate for diagnosis in ovarian cancer. J Clin Oncol; 2009 May 20;27(15_suppl):e16571

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Ep-CAM expression was examined by semiquantitative PCR in 122 ovarian tumors (92 adenocarcinomas, 10 low malignant potential (LMP) tumors, and 10 adenomas) and 10 normal ovaries.
  • RESULTS: In carcinomas as well as LMP tumors and adenomas, Ep-CAM mRNA expression was significantly elevated compared to that in normal ovary samples.
  • Ep-CAM mRNA expression level in carcinomas was significantly elevated compared to that in adenomas and Ep-CAM mRNA expression level in advanced clinical stage diseases was significantly higher than that in early stage diseases in ovarian carcinomas.

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  • (PMID = 27961514.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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23. Calistri D, Rengucci C, Casadei-Gardini A, Scarpi E, Zoli W, Falcini F, Milandri C, Amadori D, Silvestrini R: FL-DNA approach for noninvasive early diagnosis of colorectal cancer in FOBT-screened patients. J Clin Oncol; 2009 May 20;27(15_suppl):11062

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Of the 560 individuals with FOBT-positive stool subjected to colonoscopy, 26 were diagnosed with adenocarcinoma, 264 with high-grade adenoma and 54 with low-grade adenoma.
  • More than one third (216) of the group had only benign disease (hemorrhoids, diverticulitis, inflammation, etc), hyperplastic polyps or nothing.
  • RESULTS: Using a cut-off of 10 ng, the molecular analysis detected over 90% of the colorectal cancers and about 50% of the high- and low-grade adenomas.
  • A more in depth DNA stool evaluation in negative FOBT individuals could reveal the test's usefulness in unmasking colorectal tumors and adenomas missed by FOBT.

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  • (PMID = 27963138.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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24. Kobayashi T, Mori Y, Uchiyama Y, Kida Y, Fujitani S: Long-term results of gamma knife surgery for growth hormone-producing pituitary adenoma: is the disease difficult to cure? J Neurosurg; 2005 Jan;102(s_supplement):119-123

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term results of gamma knife surgery for growth hormone-producing pituitary adenoma: is the disease difficult to cure?
  • OBJECT: The authors conducted a study to determine the long-term results of gamma knife surgery for residual or recurrent growth hormine (GH)-producing pituitary adenomas and to compare the results with those after treatment of other pituitary adenomas.
  • The mean tumor diameter was 19.2 mm and volume was 5.4 cm<sup>3</sup>.
  • The tumor resolution rate was 2%, the response rate 68.3%, and the control rate 100%.

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  • (PMID = 28306435.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; gamma knife surgery / growth hormone—producing pituitary adenoma / insulin-like growth factor
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25. Fostira F, Panopoulos C, Papademitriou K, Lypas G, Lypas G, Barbounis V, Efremidis A, Yannoukakos D: A novel mutation in MUTYH-associated polyposis (MAP) syndrome. J Clin Oncol; 2009 May 20;27(15_suppl):e15022

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : e15022 Background: MUTYH-associated polyposis (MAP) syndrome is inherited as a recessive trait and is characterized by the intrinsic phenotypic feature of adenomas present at the individual's colorectum.
  • In the case of non-surgical removal of these polyps, adenoma will transform to carcinoma.

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  • (PMID = 27964415.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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26. Figer A, Shacham-Shmueli E, Liberman E, Sagiv E, Hall MJ, Dolkart O, Kazanov D, Kraus S, Neugut AI, Inbar M, Arber N: Effect of the I1307K polymorphism in APC confers a higher risk for polyp recurrence in Jewish Ashkenazi carriers. J Clin Oncol; 2009 May 20;27(15_suppl):e22003

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : e22003 Background: The I1307K adenomatous polyposis coli gene variant, prevalent among Ashkenazi Jews, may increase risk for colorectal neoplasia [colorectal cancer (CRC) and CR adenoma].
  • The overall adjusted odds ratio (OR) for CR neoplasia among carriers was 1.3 (1.0 -1.7, p=0.049).
  • Among Ashkenazi Jews, the I1307K variant was significantly more prevalent among persons with a personal or family history (1<sup>st</sup> degree) of CR neoplasia (p=0.01) as compared to Ashkenazi Jews with no family history.
  • The histopathological features of adenomas and cancers did not differ between carriers and non-carriers.
  • No interactions were found between the I1307K variant and demographic, lifestyle, or dietary modifiers that independently modulated the risk for CR neoplasia.
  • CONCLUSIONS: In the general population, the APC I1307K variant does not change the risk or prognosis of colorectal neoplasia in carriers and does not necessarily change their clinical practice.
  • Nevertheless, the variant, which is more prevalent among high risk individuals of Ashkenazi Jewish origin, is an important risk factor for the assessment of recurrence of neoplasia as it confers a higher risk for polyp recurrence in this population.

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  • (PMID = 27963171.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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27. Scheithauer BW, Gaffey TA, Lloyd RV, Sebo TJ, Kovacs KT, Horvath E, Yapıcıer Ö, Young WF, Meyer FB, Kuroki T, Riehle DL, Laws ER: Pathobiology of Pituitary Adenomas and Carcinomas. Neurosurgery; 2006 Aug 01;59(2):341-353

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pathobiology of Pituitary Adenomas and Carcinomas.

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  • (PMID = 28180650.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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28. Pucciarelli S, Enzo M, Agostini M, Pizzini S, Del Bianco P, Lonardi S, Friso M, Mescoli C, Urso E, Nitti D: Cell-free circulating DNA as a promising marker of colorectal cancer detection and progression. J Clin Oncol; 2009 May 20;27(15_suppl):11059

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • It has been suggested that cfDNA (ALU repeats of 115 bp, representative of total DNA; ALU repeats of 247 DNA, representative of tumor DNA) may be associated with presence of tumor.
  • METHODS: cfDNA was extracted from plasma samples from 136 patients with primary CRC at different stages [median age 64 yrs; male/female 78/58; stages I-II, 61; stages III-IV, 75], and from 24 patients with adenomas [median age 67 yrs; male/female 17/7)] and from 55 clean-colon healthy subjects [median age 56 yrs; male/female 13/43).
  • The levels of cfDNA (ALU-115, ALU-247) of CRC patients (stages I-II and stages III-IV) were compared with those of healthy subjects and patients with adenoma.
  • RESULTS: The median concentrations of total cfDNA (ALU115) in the plasma samples from patients with stages III-IV and stages I-II CRC, adenoma and normal controls were 52,4, 11.9; 1.9, and 1.7 ng/ml, respectively (p<.0001).
  • The corresponding figures for tumor-related cfDNA (ALU247) were 48.8, 4.7, 2.2, and 0.7 ng/ml, respectively. (p<.0001).
  • With a cut-off of 3.04, cfDNA tumor-related (ALU247) showed a sensitivity of 77.94 (95% CI 70.0-84.6) and a specificity of 82.28 (95% CI 72.1-90.0) in distinguishing patients with CRC from non-CRC [AUC: 0.864 (95% CI 0.81-0,91), p-value=.0001].
  • The findings of the current study require to be confirmed on larger cohorts of patients with CRC and colonic adenoma.

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  • (PMID = 27963165.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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29. Lozoya-González D, Farca-Belsaguy A, Peláez-Luna M, Vázquez-Ballesteros E, González-Galeote E, Salceda-Otero JC: [Endoscopic resection of ampullary adenoma.]. Rev Gastroenterol Mex; 2010;75(1):89-92

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Endoscopic resection of ampullary adenoma.].
  • [Transliterated title] Resección endoscópica de adenoma del ámpula de Vater.
  • Ampullary adenomas can occur sporadically or as part of familial adenomatous polyposis syndrome.
  • Recurrence of adenomatous lesions treated endoscopically is 30%.
  • We present the case of a patient with an ampulla of Vater s adenoma successfully resected endoscopically previous assessment of the lesion by endoscopic ultrasound.
  • [MeSH-major] Adenoma / surgery. Ampulla of Vater. Common Bile Duct Neoplasms / surgery. Endoscopy, Digestive System

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  • (PMID = 20423788.001).
  • [ISSN] 0375-0906
  • [Journal-full-title] Revista de gastroenterología de México
  • [ISO-abbreviation] Rev Gastroenterol Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
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30. Lara C, Porras V, Jurado P, Arredondo F: [Metanephric adenoma. Case report]. Arch Esp Urol; 2007 Nov;60(9):1.122-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Metanephric adenoma. Case report].
  • [Transliterated title] Adenoma metanéfrico. Presentación de un caso.
  • OBJECTIVE: Metanephric adenoma is an unfrequent renal neoplasm, usually asymptomatic.
  • METHODS/RESULTS: We report the case of a 67 years old woman with a metanephric adenoma.
  • At one end of the pathologic spectrum are the metanephric adenomas.
  • These tumors usually behave in a benign fashion.
  • It is important to differentiate metanephric adenoma from clinically aggressive renal tumors.
  • [MeSH-major] Adenoma / diagnosis. Kidney Neoplasms / diagnosis

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  • (PMID = 18077869.001).
  • [ISSN] 0004-0614
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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31. Sierra-Montenegro E, Rocha-Ramírez JL, Villaneuva-Sáenz E, de la Serna-Ortiz I, Fernández-Rivero JM, Soto-Quirino R: [Villous adenoma of the rectum with severe hydroelectric alterations. Report of two cases]. Cir Cir; 2007 Sep-Oct;75(5):377-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Villous adenoma of the rectum with severe hydroelectric alterations. Report of two cases].
  • [Transliterated title] Adenoma velloso de recto con alteración hidroelectrolítica severa. Informe de dos casos.
  • BACKGROUND: Approximately 10% of all colorectal adenomas are constituted by villous adenomas.
  • We report two cases with villous adenoma that presented hydroelectrolytic depletion with clinical and surgical management, exclusively.
  • Upon rectal exam we found a sessile, exophitic soft tumor with irregular surface of approximately 10 cm in diameter.
  • We also performed a transanal resection of tumor reporting villous adenoma.
  • During the rectal exam we identified a sessile, polypoid, 5-cm diameter tumor that did not involve deep planes.
  • CONCLUSIONS: Size and location of the villous adenoma are related to the production of mucus secretory diarrhea.
  • In every patient with presence of mucus, persistent diarrhea and occasional rectal bleeding of 1 month, it is necessary to carry out lower endoscopy to rule out the presence of villous adenoma.
  • [MeSH-major] Adenoma, Villous / complications. Rectal Neoplasms / complications. Water-Electrolyte Imbalance / etiology

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  • (PMID = 18158885.001).
  • [ISSN] 0009-7411
  • [Journal-full-title] Cirugía y cirujanos
  • [ISO-abbreviation] Cir Cir
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
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32. Turrini R, Lanzani G, Salmi A: [Gallbladder adenoma with focal adenocarcinoma: a case report]. Recenti Prog Med; 2007 Oct;98(10):506-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Gallbladder adenoma with focal adenocarcinoma: a case report].
  • [Transliterated title] Adenoma con focale adenocarcinoma della colecisti: descrizione di un caso.
  • Gallbladder polyps represent a frequent and asymptomatic finding on abdominal sonography.
  • Video-laparoscopic cholecystectomy was performed, and histological examination of the lesion revealed a severely dysplastic tubular adenoma and chronic cholecystitis.
  • To our knowledge, this is the first report of a gallbladder polyp already presenting severe dysplasia in a young Caucasian male without risk factors.
  • [MeSH-major] Adenoma / diagnosis. Cholecystectomy, Laparoscopic. Gallbladder Neoplasms / diagnosis. Polyps / complications
  • [MeSH-minor] Adult. Cholecystitis / complications. Cholecystitis / diagnosis. Cholecystitis / surgery. Chronic Disease. Humans. Male. Video-Assisted Surgery

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  • (PMID = 17970176.001).
  • [ISSN] 0034-1193
  • [Journal-full-title] Recenti progressi in medicina
  • [ISO-abbreviation] Recenti Prog Med
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Italy
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33. Kushima R, Vieth M: [Tubular adenoma of the stomach with special reference to the Japanese criteria and pyloric gland adenoma]. Pathologe; 2010 May;31(3):177-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Tubular adenoma of the stomach with special reference to the Japanese criteria and pyloric gland adenoma].
  • [Transliterated title] Das tubuläre Magenadenom. Mit Darstellung der Japanischen Kriterien unter Berücksichtigung des "pyloric gland adenoma"
  • The term gastric adenoma usually refers to a flat adenoma of the intestinal type.
  • Adenomas of the gastric type, so-called pyloric gland adenomas (PGA), which was first characterized by German and Japanese pathologists in 1990, have been regarded as exceptional until recently.
  • American gastrointestinal pathologists have finally recognized this disease entity in 2009.
  • In this article we introduce the Japanese criteria of the gastric adenoma and review and discuss the clinical pathological and molecular aspects of PGAs.
  • [MeSH-major] Adenoma / pathology. Gastric Mucosa / pathology. Intestinal Neoplasms / genetics. Intestinal Neoplasms / pathology. Stomach Neoplasms / genetics. Stomach Neoplasms / pathology

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  • (PMID = 20349063.001).
  • [ISSN] 1432-1963
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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34. Horányi J, Duffek L, Kemenes M, Szlávik R, Darvas K, Dabasi G, Lakatos P, Tóth M: [New intraoperative diagnostic methods parathyroid surgery. Adenoma localization by gamma probe]. Orv Hetil; 2005 Jul 3;146(27):1443-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [New intraoperative diagnostic methods parathyroid surgery. Adenoma localization by gamma probe].
  • [Transliterated title] Uj, intraoperatív diagnosztikus módszerek a mellékpajzsmirigy-sebészetben: gamma-szondás adenoma-lokalizáció.
  • INTRODUCTION: The key to heal primary hyperparathyroidism is to find the hyper functioning parathyroid gland(s).
  • METHODS: At 122 patients undergoing parathyroidectomy in last 5 years with diagnosis of primary hyperparathyroidism perioperative sestamibi scanning by gamma probe was taken to localize the adenoma.
  • RESULTS: Because of the thyroid lobes also accumulate sestamibi the localizability of adenomas depended on direction of scanning.
  • Localization of adenomas by percutaneous measurement was correct in 36.1% of cases and by perioperative direct scanning in 66.4%.
  • Furthermore, ex vivo scan of removed adenomas showed impressively high activity in all cases.
  • CONCLUSIONS: In their experience sestamibi scanning lightens the operation only in a part of cases but probably it will be the most important method of localization if isotope selectively accumulating in parathyroid gland could be found.
  • [MeSH-major] Adenoma / diagnosis. Adenoma / surgery. Gamma Rays. Parathyroid Diseases / diagnosis. Parathyroid Diseases / surgery. Parathyroidectomy

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  • (PMID = 16089105.001).
  • [ISSN] 0030-6002
  • [Journal-full-title] Orvosi hetilap
  • [ISO-abbreviation] Orv Hetil
  • [Language] hun
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Hungary
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi
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35. Garduno-García Jde J, Reza-Albarrán A, Márquez MA, Pérez FJ: [Adrenal adenoma as a cause of Cushing's syndrome: twenty years' experience in a referral center in Mexico]. Endocrinol Nutr; 2010 Nov;57(9):421-5
MedlinePlus Health Information. consumer health - Cushing's Syndrome.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Adrenal adenoma as a cause of Cushing's syndrome: twenty years' experience in a referral center in Mexico].
  • [Transliterated title] Adenoma adrenal como etiología de síndrome de Cushing: veinte años de experiencia en un centro mexicano de tercer nivel.
  • Adrenal adenomas are an uncommon cause of adult CS.
  • OBJECTIVE: To describe the characteristics and outcome of patients with CS caused by adrenal adenomas in a referral center.
  • METHODS: We performed a retrospective cross-sectional observational study of patients with a diagnosis of CS caused by adrenal adenomas managed in our center over a 20-year period.
  • The results of dynamic testing with dexamethasone suggested adrenal adenoma in 100% of the patients.
  • Seventy percent of adenomas were found in the left gland.
  • ACTH measurement in our center was not reliable in identifying adrenal adenoma as a cause of CS.
  • [MeSH-major] Adenoma / complications. Adrenal Gland Neoplasms / complications. Cushing Syndrome / etiology

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  • MedlinePlus Health Information. consumer health - Adrenal Gland Cancer.
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  • [Copyright] Copyright © 2010 SEEN. Published by Elsevier Espana. All rights reserved.
  • (PMID = 20863774.001).
  • [ISSN] 1579-2021
  • [Journal-full-title] Endocrinología y nutrición : órgano de la Sociedad Española de Endocrinología y Nutrición
  • [ISO-abbreviation] Endocrinol Nutr
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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36. Verger-Kuhnke AB, Reuter M, Epple W, Ungemach G, Beccaría ML: [Combined treatment of prostatic adenoma with the 80 Watt KTP-laser and low-pressure transurethral resection]. Actas Urol Esp; 2006 Apr;30(4):394-401
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  • [Title] [Combined treatment of prostatic adenoma with the 80 Watt KTP-laser and low-pressure transurethral resection].
  • [Transliterated title] Tratamiento combinado del adenoma prostático con el KPT-láser de 80 Watt y la resección transuretral de baja presión.
  • INTRODUCTION: The purpose of this prospective study is to determine the effectiveness of method for vaporisation and elimination of the prostate adenoma.
  • The additional Resection was carried out in those patients with large adenomas or to have accentuated middle lobule.
  • CONCLUSION: Our study reveals the advantages of combining both operative procedures to mainly obtain a better result in the ablation of the prostate adenoma in prostates of great size.
  • [MeSH-major] Adenoma / surgery. Laser Therapy / methods. Prostatectomy / methods. Prostatic Neoplasms / surgery. Video-Assisted Surgery / methods

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  • (PMID = 16838611.001).
  • [ISSN] 0210-4806
  • [Journal-full-title] Actas urologicas españolas
  • [ISO-abbreviation] Actas Urol Esp
  • [Language] spa
  • [Publication-type] Comparative Study; Controlled Clinical Trial; English Abstract; Journal Article
  • [Publication-country] Spain
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37. Horvath E, Kovacs K, Smyth HS, Cusimano M, Singer W: Silent adenoma subtype 3 of the pituitary--immunohistochemical and ultrastructural classification: a review of 29 cases. Ultrastruct Pathol; 2005 Nov-Dec;29(6):511-24
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Silent adenoma subtype 3 of the pituitary--immunohistochemical and ultrastructural classification: a review of 29 cases.
  • The silent adenoma subtype 3 (SAS-3) of undetermined cellular derivation is a seemingly nonfunctioning aggressive pituitary tumor with a high recurrence rate.
  • At the time of diagnosis SAS-3s are macro- or giant adenomas particularly aggressive in young individuals, especially women.
  • Ultrastructurally, the large polar adenoma cells contain abundant RER, masses of SER, extensive multipolar Golgi apparatus, and unevenly clustered mitochondria, displaced by RER and SER, which may show close spatial relationship to RER.
  • Some tumors express somatostatin receptors and respond well to somatostatin analogues, offering long-term control in patients with residual tumor.
  • [MeSH-major] Adenoma / metabolism. Adenoma / ultrastructure. Pituitary Neoplasms / metabolism. Pituitary Neoplasms / ultrastructure

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  • (PMID = 16316952.001).
  • [ISSN] 0191-3123
  • [Journal-full-title] Ultrastructural pathology
  • [ISO-abbreviation] Ultrastruct Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 15
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38. Moshkin O, Scheithauer BW, Syro LV, Velasquez A, Horvath E, Kovacs K: Collision tumors of the sella: craniopharyngioma and silent pituitary adenoma subtype 3: case report. Endocr Pathol; 2009;20(1):50-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Collision tumors of the sella: craniopharyngioma and silent pituitary adenoma subtype 3: case report.
  • Collision tumors of the sella turcica are rare and consist mainly of more than one type of pituitary adenoma, usually a corticotropin- and a prolactin-producing adenoma.
  • The association of a craniopharyngioma and a pituitary adenoma is rare.
  • Herein, we report the first case of an association between craniopharyngioma and silent pituitary adenoma subtype 3.
  • It involved a 12-year-old boy who underwent a frontal craniotomy with surgical removal of a calcified sellar tumor.
  • Histology revealed an adamantinomatous craniopharyngioma; however, by electron microscopy, there was conclusive evidence of adenoma cells showing the ultrastructural features of silent pituitary adenoma subtype 3.
  • [MeSH-major] Adenoma / ultrastructure. Craniopharyngioma / ultrastructure. Neoplasms, Multiple Primary / pathology. Pituitary Neoplasms / ultrastructure

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  • (PMID = 19238590.001).
  • [ISSN] 1046-3976
  • [Journal-full-title] Endocrine pathology
  • [ISO-abbreviation] Endocr. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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39. Spisák S, Kalmár A, Galamb O, Sipos F, Wichmann B, Molnár B, Tulassay Z: [Identification of methylation related genes from laser capture microdissected colon samples during investigation of adenoma-carcinoma sequence]. Orv Hetil; 2010 May 16;151(20):805-14

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  • [Title] [Identification of methylation related genes from laser capture microdissected colon samples during investigation of adenoma-carcinoma sequence].
  • [Transliterated title] Metilációs szabályozás alatt álló gének azonosítása lézerrel kimetszett vastagbéldaganat-sejtekben az adenoma-carcinoma sorrend vizsgálata során.
  • This event can occur in several manners in the tumor microenvironment and there are still not any effective and high-throughput methods for genome-wide analysis of this phenomenon.
  • In parallel, 5000 epithelial cells were collected with laser microdissection (LCM) from normal, adenoma and tumorous colonic samples.
  • The genes with gradually decreasing expression along the adenoma-carcinoma sequence were identified.
  • CONCLUSION: The regulation of the identified genes showing decreased expression during the adenoma-carcinoma sequence, can be associated with DNA methylation.
  • On the basis of our results, the set of genes including tumorsuppressors can be determined genome-widely, which can be key factors in the formation and the prognosis of the disease.
  • [MeSH-major] Adenoma / genetics. Carcinoma / genetics. Cell Transformation, Neoplastic / genetics. Colonic Neoplasms / diagnosis. Colonic Neoplasms / genetics. DNA Methylation. Lasers

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  • (PMID = 20442051.001).
  • [ISSN] 0030-6002
  • [Journal-full-title] Orvosi hetilap
  • [ISO-abbreviation] Orv Hetil
  • [Language] hun
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Hungary
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40. Guignat L, Assie G, Bertagna X, Bertherat J: [Corticotroph adenoma]. Presse Med; 2009 Jan;38(1):125-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Corticotroph adenoma].
  • Corticotroph adenomas cause ACTH oversecretion responsible for Cushing's disease.
  • Ninety percent of corticotroph adenomas are microadenomas, sometime not visible on MRI.
  • Corticotroph macroadenomas are rare, but can be responsible for an aggressive tumor.
  • Cushing's disease diagnosis requires careful hormonal and imaging investigations, aiming first at the diagnosis of Cushing's syndrome and in a second step at the diagnosis of its pituitary origin.
  • The treatment of corticotroph adenoma is mainly based on pituitary surgery.
  • [MeSH-major] ACTH-Secreting Pituitary Adenoma / complications. Pituitary ACTH Hypersecretion / etiology. Pituitary Neoplasms / complications

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  • (PMID = 19041214.001).
  • [ISSN] 2213-0276
  • [Journal-full-title] Presse medicale (Paris, France : 1983)
  • [ISO-abbreviation] Presse Med
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 9002-60-2 / Adrenocorticotropic Hormone; 9015-71-8 / Corticotropin-Releasing Hormone; WI4X0X7BPJ / Hydrocortisone
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41. Magalhães E, Eugénio L, Bernardo J, Carvalho L, Antunes M: [Pleomorphic adenoma of the trachea. Case report]. Rev Port Pneumol; 2006 Mar-Apr;12(2):177-84

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pleomorphic adenoma of the trachea. Case report].
  • [Transliterated title] Adenoma pleomórfico da traqueia. Caso clínico.
  • The authors present a case of a pleomorphic adenoma of the trachea, diagnosed during the clinical evaluation of a suspected COPD or lung cancer in a heavy smoker patient with a positive family history of oncologic diseases.
  • [MeSH-major] Adenoma, Pleomorphic / surgery. Tracheal Neoplasms / surgery

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  • (PMID = 16804633.001).
  • [ISSN] 0873-2159
  • [Journal-full-title] Revista portuguesa de pneumologia
  • [ISO-abbreviation] Rev Port Pneumol
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Portugal
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42. Mac Gregor Gooch AL, Guillermina Velasco Diaz G, Carranza Lira S: [Virilizing adrenal adenoma: a report of a case]. Ginecol Obstet Mex; 2005 May;73(5):261-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Virilizing adrenal adenoma: a report of a case].
  • [Transliterated title] Adenoma suprarrenal virilizante: comunicación de un caso.
  • It is presented the case of a 26 year-old woman that suffered from amenorrhea, hirsutism, voice deepening, reduction of mammary volume and 10 kg weight loss, without response to different treatments.
  • The CAT scan and nuclear magnetic imaging of adrenal glands showed an oval retroperitoneal image of 7.2 x 6.5 x 8.4 cm at the right adrenal gland.
  • Surgery was performed and the right adrenal gland excised.
  • The histopathologic report indicated a benign cortical adenoma.
  • [MeSH-major] Adenoma / complications. Adrenal Cortex Neoplasms / complications. Virilism / etiology

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  • (PMID = 21966765.001).
  • [ISSN] 0300-9041
  • [Journal-full-title] Ginecología y obstetricia de México
  • [ISO-abbreviation] Ginecol Obstet Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
  • [Chemical-registry-number] 409J2J96VR / Androstenedione; 57B09Q7FJR / Dehydroepiandrosterone Sulfate
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43. Bioulac-Sage P, Rebouissou S, Thomas C, Blanc JF, Saric J, Sa Cunha A, Rullier A, Cubel G, Couchy G, Imbeaud S, Balabaud C, Zucman-Rossi J: Hepatocellular adenoma subtype classification using molecular markers and immunohistochemistry. Hepatology; 2007 Sep;46(3):740-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hepatocellular adenoma subtype classification using molecular markers and immunohistochemistry.
  • Hepatocellular adenomas (HCA) with activated beta-catenin present a high risk of malignant transformation.
  • To permit robust routine diagnosis to allow for HCA subtype classification, we searched new useful markers.
  • CONCLUSION: We refined HCA classification and its phenotypic correlations, providing a routine test to classify hepatocellular adenomas using simple and robust immunohistochemistry.
  • [MeSH-major] Adenoma, Liver Cell / classification. Adenoma, Liver Cell / pathology. Biomarkers, Tumor / analysis. Liver Neoplasms / classification. Liver Neoplasms / pathology


44. Palomar Asenjo V, Borràs Perera M, Soteras Ollé J, Palomar García V: [Parotid gland myoepitheliomas. Differential diagnosis with pleomorphic adenoma]. An Otorrinolaringol Ibero Am; 2006;33(4):409-16

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  • [Title] [Parotid gland myoepitheliomas. Differential diagnosis with pleomorphic adenoma].
  • [Transliterated title] Mioepiteliomas de glándula parótida. Diagnóstico diferencial con el adenoma pleomorfo.
  • Myoepitheliomas are rare benign tumours of head and neck.
  • The parotid gland is the most common site of origin.
  • It consists on proliferation of myoepithelial cells and it shows some features similar to preomorphic adenoma although the ductal elements are very low.
  • We report two cases of parotid gland myoepithelioma confirmed by immunohistochemistry.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Myoepithelioma / pathology. Parotid Neoplasms / pathology

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  • (PMID = 16910397.001).
  • [ISSN] 0303-8874
  • [Journal-full-title] Anales otorrinolaringológicos ibero-americanos
  • [ISO-abbreviation] An Otorrinolaringol Ibero Am
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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45. Giallauria F, De Lorenzo A, Manakos A, Pilerci F, Psaroudaki M, De Cristofaro A, Lucci R, Del Forno D, Vigorito C: [Inflammatory syndrome after thoracic aortic endoprosthesis implantation associated with cortico-suprarenal adenoma]. Monaldi Arch Chest Dis; 2005 Mar;64(1):59-62
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  • [Title] [Inflammatory syndrome after thoracic aortic endoprosthesis implantation associated with cortico-suprarenal adenoma].
  • [Transliterated title] Sindrome infiammatoria post-impianto di endoprotesi aortica toracica associata ad adenoma surrenalico.
  • We report a case of a 68-year-old patient, admitted with diagnosis of aneurysm of the descending thoracic aorta to the Department of Cardiac Surgery, where he underwent percutaneous endovascular application of 4 endoprostheses in the descending thoracic aorta.
  • Further investigations showed left cortical-suprarenal adenoma.

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  • (PMID = 16128168.001).
  • [ISSN] 1122-0643
  • [Journal-full-title] Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace
  • [ISO-abbreviation] Monaldi Arch Chest Dis
  • [Language] ITA
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Italy
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46. Cohn-Zurita F, Guinto-Balanzar G, Pérez-Cerdán H: [Neurocysticercosis associated with pituitary adenoma. Case report and literature review]. Cir Cir; 2006 Jan-Feb;74(1):47-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Neurocysticercosis associated with pituitary adenoma. Case report and literature review].
  • [Transliterated title] Cisticercosis cerebral asociada con adenoma pituitario. Reporte de un caso y revisión de la literatura.
  • However, the clinical association between pituitary adenoma and suprasellar cysts is unknown.
  • Imaging studies including CT and MRI revealed a moderate size pituitary adenoma along with multiple cysts located in the subarachnoid cisterns in the Sylvian fissure and around the suprasellar cistern.
  • The patient subsequently underwent surgical exploration by means of a right frontotemporal craniotomy with pituitary adenoma resection and cyst removal.
  • The histopathological exam was consistent with non-functioning pituitary adenoma and racemosus cysticercosis.
  • CONCLUSIONS: There are no reports of a clinical association between pituitary adenoma and racemosus cysticercosis.
  • [MeSH-major] Adenoma / complications. Neurocysticercosis / complications. Pituitary Neoplasms / complications

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  • (PMID = 17257488.001).
  • [ISSN] 0009-7411
  • [Journal-full-title] Cirugía y cirujanos
  • [ISO-abbreviation] Cir Cir
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Mexico
  • [Number-of-references] 5
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47. Torres Gómez FJ, Torres Olivera FJ, García Escudero A: [Predominantly cystic renal metanephric adenoma. Case report]. Arch Esp Urol; 2006 Jan-Feb;59(1):90-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Predominantly cystic renal metanephric adenoma. Case report].
  • [Transliterated title] Adenoma metanéfrico renal de predominio quístico. A propósito de un caso.
  • OBJECTIVES: Metanephric adenoma is a relatively unfrequent asymptomatic embryogenic renal tumor which is generally diagnosed by an abdominal diagnostic tests indicated for other reasons.
  • Differential diagnosis with benign and malignant tumors has to be performed.
  • METHODS/RESULTS: We report one case of metanephric adenoma with intense necrotic-hemorrhagic and cystic changes with a size not previously referred in the literature.
  • CONCLUSIONS: Cystic and hemorrhagic changes in benign renal tumors make differential diagnosis with malignant tumors mandatory Surgery is necessary in almost all cases and histologic study will give the diagnosis.
  • [MeSH-major] Adenoma / pathology. Kidney Neoplasms / pathology

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  • (PMID = 16568702.001).
  • [ISSN] 0004-0614
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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48. Lugli A, Jass JR: Types of colorectal adenoma. Verh Dtsch Ges Pathol; 2006;90:18-24
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  • [Title] Types of colorectal adenoma.
  • While most colorectal polyps can be classified as either adenomas (AD) or hyperplastic polyps (HP), approximately 5 % have some of the features of these lesions but are distinguishable from both.
  • These lesions include sessile serrated adenoma or polyp (SSP), mixed polyp (MP), and traditional serrated adenoma (SA).
  • [MeSH-major] Adenoma / classification. Adenoma / pathology. Colorectal Neoplasms / classification. Colorectal Neoplasms / pathology
  • [MeSH-minor] Colonic Polyps / pathology. Disease Progression. Humans


49. Alvarez Marcos CA, Méndez Alvarez JR, Domínguez Iglesias F, Hevia Llamas R, Fernández Espina H, Junco Petrement P: [Unusual cervical cyst. Adenocarcinoma ex-pleomorphic adenoma of a minor salivary gland]. Acta Otorrinolaringol Esp; 2006 Nov;57(9):429-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Unusual cervical cyst. Adenocarcinoma ex-pleomorphic adenoma of a minor salivary gland].
  • [Transliterated title] Quiste cervical inusual. adenocarcinoma ex-adenoma pleomorfo de glándula salival menor.
  • It is even more uncommon that the malignant tumour has its origin in a minor salivary gland as it is the malignant transformation of a pleomorphic adenoma.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma, Pleomorphic / pathology. Head and Neck Neoplasms / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands, Minor / pathology

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  • (PMID = 17184013.001).
  • [ISSN] 0001-6519
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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50. Pino Rivero V, Pantoja Hernández CG, González Palomino A, Mora Santos ME, Pardo Romero R, Trinidad Ramos G, Montero García C, Blasco Huelva A: [Reoperation because of ectopic parathyroid adenoma with previous removal of lipothymoma. Importance of intraoperative PTH]. An Otorrinolaringol Ibero Am; 2006;33(6):565-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Reoperation because of ectopic parathyroid adenoma with previous removal of lipothymoma. Importance of intraoperative PTH].
  • [Transliterated title] Reintervención por adenoma ectópico de paratiroides con extirpación previa de lipotimoma. Importancia de la PTH intraoperatoria.
  • Sometimes the surgery of hyperparathyroidism is not easy and the surgical team find difficulties to locate the pathological gland or glands.
  • We report a case of primary hyperparathyroidism due to an ectopic parathyroid adenoma which required two interventions.
  • First we removed what it seems an adenoma but resulted to be a lipotimoma.
  • In the reintervention practiced one week later, having then the rapid or turbo intraoperative PTH and previous digital scintigraphy, it was possible to remove an adenoma histologically confirmed, with 3,5 cm diameter located in depth to right thyroid lobe towards the superior mediastinal straits.
  • [MeSH-major] Adenoma / surgery. Parathyroid Neoplasms / surgery. Thymoma / surgery. Thymus Neoplasms / surgery

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  • (PMID = 17233271.001).
  • [ISSN] 0303-8874
  • [Journal-full-title] Anales otorrinolaringológicos ibero-americanos
  • [ISO-abbreviation] An Otorrinolaringol Ibero Am
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Parathyroid Hormone
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51. Calbo L, Campennì A, Calbo E, Catalfamo A, Sciglitano P, Niceta M, Borzì R, Lizio R, Gorgone S: [Hyperparathyroidism from mediastinal parathyroid adenoma. Case report]. G Chir; 2008 Jun-Jul;29(6-7):295-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Hyperparathyroidism from mediastinal parathyroid adenoma. Case report].
  • [Transliterated title] Iperparatiroidismo da adenoma paratiroideo a localizzazione mediastinica. Caso clinico.
  • The authors, after reviewing parathyroid gland diseases, their location, and the modern strategies that can be used for their pre-operative detection, describe a case of primary hyperparathyroidism which recently came to their attention.
  • The use of a combination of instrumental techniques (US, scintigraphy and SPEcT) enabled them to establish, prior to surgery, the mediastinal ectopic site of the parathyroid adenoma.
  • [MeSH-major] Adenoma / complications. Choristoma / complications. Hyperparathyroidism, Primary / etiology. Mediastinal Neoplasms / complications. Parathyroid Neoplasms / complications

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  • (PMID = 18544269.001).
  • [ISSN] 0391-9005
  • [Journal-full-title] Il Giornale di chirurgia
  • [ISO-abbreviation] G Chir
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Italy
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52. Hernández Sandemetrio R, Armengot Carceller M, Alba García JR, Taleb C, Jiménez Roig JP, Frías Moya-Angeler S, Basterra Alegría J: [Pleomorphic adenoma of deep lobe of the parotid gland]. Acta Otorrinolaringol Esp; 2006 Jan;57(1):56-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pleomorphic adenoma of deep lobe of the parotid gland].
  • [Transliterated title] Adenoma pleomorfo gigante de lóbulo profundo de la parótida: a propósito de un caso.
  • This report describes a case of a pleomorphic adenoma in the deep lobe of the parotid gland presented like a parapharyngeal mass, and its diagnosis and treatment.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Parotid Neoplasms / pathology
  • [MeSH-minor] Adult. Female. Humans. Magnetic Resonance Imaging. Neoplasm Staging

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  • (PMID = 16503035.001).
  • [ISSN] 0001-6519
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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53. Márquez Moyano JA, Ortega Salas R, Romero Ortiz A, Sánchez Gutiérrez R, Ostos Aumente P, Roldán Nogueras J, López Villarejo P: [Middle ear adenoma: our casuistry and revision of the literature]. Acta Otorrinolaringol Esp; 2006 Jun-Jul;57(6):288-90

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Middle ear adenoma: our casuistry and revision of the literature].
  • [Transliterated title] Adenoma de oído medio: nuestra casuística y revisión de la literatura.
  • Among them glomus tympanicum is the most frequent, followed by adenoma of the middle ear (AME).
  • [MeSH-major] Adenoma / diagnosis. Ear Neoplasms / diagnosis. Ear, Middle / pathology

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  • (PMID = 16872107.001).
  • [ISSN] 0001-6519
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 16
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54. Kim JH, Choi JW, Seo YS, Lee BJ, Yeon JE, Kim JS, Byun KS, Bak YT, Kim I, Park JJ: Inverted cystic tubulovillous adenoma involving Brunner's glands of duodenum. World J Gastroenterol; 2007 Jun 21;13(23):3262-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Inverted cystic tubulovillous adenoma involving Brunner's glands of duodenum.
  • Benign neoplasia of the duodenum are very rare.
  • Moreover, duodenal tubulovillous adenomas are more uncommon lesions.
  • The microscopic structure of tubulovillous adenoma has frond-like projection of mucosa with branching papillary structure and generally upward growth into the lumen.
  • We describe a 72-year-old man who showed aduodenal tubulovillous adenoma with unusual inverted cystic growth pattern.
  • Interestingly, this tubulovillous adenomatous lesion was interrupted by gastric metaplasia in the deep portion of the cyst and was closely surrounded by Brunner's glands.
  • Therefore, these findings argued that this adenoma arises from Brunner's glands through gastric metaplasia.
  • This is the first case of inverted cystic tubulovillous adenoma involving Brunner's glands of duodenum with gastric metaplasia.
  • [MeSH-major] Adenoma / pathology. Brunner Glands / pathology. Cysts / pathology. Duodenal Neoplasms / pathology

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  • (PMID = 17589910.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC4436617
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55. Zhu JP, Hu HT, Xiang R, Yi WH, Liu Z: [FTIR analysis of benign and malignant pleomorphic adenoma tissues]. Guang Pu Xue Yu Guang Pu Fen Xi; 2007 Jul;27(7):1295-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [FTIR analysis of benign and malignant pleomorphic adenoma tissues].
  • The FTIR (Fourier transform infrared) spectra of benign pleomorphic adenoma tissues and malignant ones were investigated using the spectrometer GX FTIR Spectroscopy.
  • The results indicated that there were infrared spectra difference between the benign adenoma tissues and the malignant ones in some bands.
  • Compared to the benign adenoma tissues, the contents of nucleic acid relative to the collagen protein and the adipose relative to the protein both increase in malignant ones.
  • [MeSH-major] Adenocarcinoma / chemistry. Adenoma / chemistry. Spectroscopy, Fourier Transform Infrared / methods

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  • (PMID = 17944398.001).
  • [ISSN] 1000-0593
  • [Journal-full-title] Guang pu xue yu guang pu fen xi = Guang pu
  • [ISO-abbreviation] Guang Pu Xue Yu Guang Pu Fen Xi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Lipids; 0 / Nucleic Acids; 0 / Proteins
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56. Lee SE, Park NH, Park IA, Kang SB, Lee HP: Tubulo-villous adenoma of the vagina. Gynecol Oncol; 2005 Feb;96(2):556-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tubulo-villous adenoma of the vagina.
  • BACKGROUND: Tubulo-villous adenomas are common in the colon and rectum, but extremely rare in the vagina.
  • As far as we know, only two cases of tubulo-villous adenoma have ever been reported.
  • We report the third case of enteric-type tubulo-villous adenoma of the vagina.
  • CASE: A 61-year-old woman presented a symptom of intermittent vaginal spotting and a tumor located outside the vaginal introitus near the urethra.
  • The tumor was excised and pathologically confirmed as a tubulo-villous adenoma.
  • CONCLUSION: Because some tubulo-villous adenomas in the colon and rectum can progress to the cancer, this case requires long-term follow-up to detect recurrence and malignant transformation.
  • [MeSH-major] Adenoma, Villous / pathology. Vaginal Neoplasms / pathology

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  • (PMID = 15661252.001).
  • [ISSN] 0090-8258
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 17
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57. Greco S, Cassinotti A, Massari A, Bossi I, Trabucchi E, Bianchi Porro G: Isolated ampullary adenoma causing biliary obstruction. J Gastrointestin Liver Dis; 2008 Sep;17(3):329-32

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Isolated ampullary adenoma causing biliary obstruction.
  • This is an interesting case of an isolated ampullary adenoma causing biliary obstruction that required surgical excision.
  • We describe a patient who presented with a six month history of recurrent attacks of typical biliary pain radiating from the right upper quadrant of the abdomen to the back, nausea and vomiting, which we attributed to a large pedunculated tubulovillous adenoma.
  • Abdominal ultrasound and endoscopic ultrasonography provided useful information in the diagnostic assessment of ampullary adenoma.
  • Sporadic duodenal adenomas are an increasingly recognized condition in those with familial adenomatous polyposis syndromes as well as sporadic cases.
  • [MeSH-major] Adenoma / complications. Ampulla of Vater. Cholestasis / etiology. Common Bile Duct Neoplasms / complications

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  • (PMID = 18836629.001).
  • [ISSN] 1841-8724
  • [Journal-full-title] Journal of gastrointestinal and liver diseases : JGLD
  • [ISO-abbreviation] J Gastrointestin Liver Dis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Romania
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58. Schittenhelm J, Ebner FH, Harter P, Bornemann A: Symptomatic intraspinal oncocytic adrenocortical adenoma. Endocr Pathol; 2009;20(1):73-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Symptomatic intraspinal oncocytic adrenocortical adenoma.
  • Benign epithelial tumors are rarely found at this site.
  • We here present the case of a 44-year-old woman with a lesion in the cauda equina that fulfilled the radiologic criteria of schwannoma and caused clinical symptoms for 3 years.
  • The excised tumor was composed of nests of large polygonal cells with eosinophilic partial granular cytoplasm.
  • The tumor showed diffuse positivity for melan-A, synaptophysin, and alpha-inhibin.
  • Ultrastructural examination showed abundant mitochondria, suggesting an oncocytic tumor.
  • The diagnosis of an oncocytic adrenal cortical adenoma was made.
  • Oncocytic tumors are rare neoplasms and they comprise non-functioning variants of adrenal cortical adenomas.
  • Immunohistochemistry excluded oncocytic paraganglioma, oncocytic meningioma, renal cell carcinoma, alveolar soft part sarcoma, and granular cell tumor.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Adrenocortical Adenoma / pathology. Spinal Cord Neoplasms / pathology

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  • (PMID = 19039533.001).
  • [ISSN] 1046-3976
  • [Journal-full-title] Endocrine pathology
  • [ISO-abbreviation] Endocr. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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59. Miguel-Pérez P, Herrera-Hernández M, Padilla-Rodríguez A, Martínez-Consuegra N: [Thyroid oncocytic adenoma. A review of the morphological spectrum in four cases]. Gac Med Mex; 2007 Nov-Dec;143(6):517-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Thyroid oncocytic adenoma. A review of the morphological spectrum in four cases].
  • [Transliterated title] Adenoma oncocítico de tiroides (adenoma de células de Hürthle). Revisión del espectro morfológico a propósito de cuatro casos.
  • In the thyroid gland, this change is a metaplastic phenomenon that takes place under different circumstances that promote cellular stress, and could even produce a true neoplasm, both benign or malignant.
  • The oncocytic adenoma, a malignant tumor will be described.
  • Tumor characteristics in all cases included: massive ischemic necrosis short after a fine needle aspiration biopsy was performed, unexpected large size, coexistence with a malignant independent neoplasm and cytological features similar to those observed in papillary carcinomas.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Thyroid Neoplasms / pathology

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  • (PMID = 18269084.001).
  • [ISSN] 0016-3813
  • [Journal-full-title] Gaceta médica de México
  • [ISO-abbreviation] Gac Med Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
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60. González-Tortosa J, Poza-Poza M, Ruiz-Espejo-Vilar A: [Pituitary adenoma apoplexy after spinal anaesthesia. Report of two cases and review of the literature]. Neurocirugia (Astur); 2009 Oct;20(5):484-93
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pituitary adenoma apoplexy after spinal anaesthesia. Report of two cases and review of the literature].
  • [Transliterated title] Apoplejía de adenoma hipofi sario no funcionante tras anestesia espinal. A propósito de dos casos.
  • We propose the arterial hypotension as a possible pathogenetic mechanism of pituitary adenoma apoplexy.
  • [MeSH-major] Adenoma / diagnosis. Anesthesia, Spinal / adverse effects. Pituitary Apoplexy / etiology. Pituitary Neoplasms / diagnosis. Postoperative Complications / etiology

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  • (PMID = 19830374.001).
  • [ISSN] 1130-1473
  • [Journal-full-title] Neurocirugía (Asturias, Spain)
  • [ISO-abbreviation] Neurocirugia (Astur)
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 72
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61. Moncet D, Isaac G, Staltari D, Tomasello A, Boronat S: [Ectopic mediastinal parathyroid adenoma. Detection with a radioisotopic probe and resolution with videothoracoscopy]. Medicina (B Aires); 2006;66(5):457-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Ectopic mediastinal parathyroid adenoma. Detection with a radioisotopic probe and resolution with videothoracoscopy].
  • [Transliterated title] Adenoma paratiroideo ectópico mediastinal. Diagnóstico por sonda de detección gamma y resección por videotoracoscopia.
  • The patient was successfully operated upon by means of a videothora-coscopic approach.
  • An attempt to detect the precise site of the adenoma with a Tc99-MIBI probe was unsuccessful because of its proximity to the myocardium, but radioactivity was confirmed on the surgical specimen after resection.
  • [MeSH-major] Adenoma / radionuclide imaging. Hyperparathyroidism, Primary / radionuclide imaging. Mediastinal Neoplasms / radionuclide imaging. Parathyroid Neoplasms / radionuclide imaging. Radiopharmaceuticals. Technetium Tc 99m Sestamibi

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  • [ErratumIn] Medicina (B Aires). 2007;67(1):31
  • (PMID = 17137179.001).
  • [ISSN] 0025-7680
  • [Journal-full-title] Medicina
  • [ISO-abbreviation] Medicina (B Aires)
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Argentina
  • [Chemical-registry-number] 0 / Parathyroid Hormone; 0 / Radiopharmaceuticals; 971Z4W1S09 / Technetium Tc 99m Sestamibi; SY7Q814VUP / Calcium
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62. Sobhonslidsuk A, Jeffers LJ, Acosta RC, Madariaga JR, Bejarano PA, Guerra JJ, Tzakis AG, Schiff ER: Budd-Chiari-like presentation of hepatic adenoma. J Gastroenterol Hepatol; 2005 Apr;20(4):653-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Budd-Chiari-like presentation of hepatic adenoma.
  • Hepatic adenoma is a benign tumor characterized by its hypervascularity.
  • Hepatic adenoma tends to occur more frequently in women and is related to the use of contraceptive hormones, androgenic/anabolic steroids, pregnancy, glycogen storage diseases and hemochromatosis.
  • Tumor resection was carried out successfully.
  • The final diagnosis of this case was multiple hepatic adenomas.
  • [MeSH-major] Adenoma / complications. Adenoma / diagnosis. Budd-Chiari Syndrome / diagnosis. Budd-Chiari Syndrome / etiology. Liver Neoplasms / complications. Liver Neoplasms / diagnosis. Puerperal Disorders / diagnosis

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  • (PMID = 15836723.001).
  • [ISSN] 0815-9319
  • [Journal-full-title] Journal of gastroenterology and hepatology
  • [ISO-abbreviation] J. Gastroenterol. Hepatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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63. Jha S, Kumar S: TSH secreting pituitary adenoma. J Assoc Physicians India; 2009 Jul;57:537-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] TSH secreting pituitary adenoma.
  • Thyrotropin (TSH) secreting pituitary adenomas are a very rare cause of hyperthyroidism.
  • TSH secreting tumors account for 1 percent of all pituitary adenoma.
  • They are a rare cause of thyrotoxicosis in which adenomas completely or partially lose feedback regulation of thyroid hormones and lead to sustained stimulation of thyroid gland.
  • The most definitive treatment of thyrotropin (TSH)-secreting pituitary adenomas is transsphenoidal removal of tumor after restoring euthyroidism.
  • We report a case of pituitary adenoma associated with elevated serum free thyroid hormones and non-suppressed TSH levels.
  • [MeSH-major] Adenoma / secretion. Pituitary Neoplasms / secretion. Thyrotropin / secretion

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  • (PMID = 20329419.001).
  • [ISSN] 0004-5772
  • [Journal-full-title] The Journal of the Association of Physicians of India
  • [ISO-abbreviation] J Assoc Physicians India
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 9002-71-5 / Thyrotropin
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64. Ihrler S, Schwarz S, Zengel P, Guntinas-Lichius O, Kirchner T, Weiler C: [Pleomorphic adenoma: pitfalls and clinicopathological forms of progression]. Pathologe; 2009 Nov;30(6):446-56
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pleomorphic adenoma: pitfalls and clinicopathological forms of progression].
  • [Transliterated title] Das pleomorphe Adenom: Pitfalls in der Diagnostik und klinisch-pathologische Progressionsformen.
  • In the majority of cases the diagnosis of pleomorphic adenoma (PA) is straightforward.
  • In "monomorphic" types of PA problems may result: Epithelial-rich PA need to be distinguished from basal cell adenoma or canalicular adenoma.
  • The different progression steps of carcinoma ex pleomorphic adenoma (CEPA), starting with intraductal carcinoma, are highly relevant with respect to prognosis and therapy.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Adenoma, Pleomorphic / pathology. Salivary Gland Neoplasms / diagnosis. Salivary Gland Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Cell Transformation, Neoplastic / pathology. Diagnosis, Differential. Disease Progression. Female. Humans. Middle Aged. Neoplasm Invasiveness. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Neoplasm Staging. Reoperation. Salivary Ducts / pathology. Salivary Glands / pathology

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  • (PMID = 19844715.001).
  • [ISSN] 1432-1963
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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65. Lee SL, Lee CY, Silver SM, Kuhar S: Nasopharyngeal pleomorphic adenoma in the adult. Laryngoscope; 2006 Jul;116(7):1281-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nasopharyngeal pleomorphic adenoma in the adult.
  • INTRODUCTION: Salivary gland tumors account for less than 5% of all neoplasms in the head and neck, with pleomorphic adenoma being the most common type.
  • These typically arise in the palate, but we report a rare case of nasopharyngeal pleomorphic adenoma in an adult.
  • Histologic evaluation demonstrated pleomorphic adenoma.
  • DISCUSSION: Pleomorphic adenomas seldom present as nasopharyngeal masses and have a nonspecific appearance on endoscopy.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Nasopharyngeal Neoplasms / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands, Minor

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  • (PMID = 16826077.001).
  • [ISSN] 0023-852X
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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66. Marcos Ordóñez M, García Lagarto E, Santos Pérez J, Moráis Pérez D: [Carcinoma on pleomorphic adenoma in cervical salivary heteropia. Handling of one case and literature review]. Acta Otorrinolaringol Esp; 2007 Oct;58(8):371-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Carcinoma on pleomorphic adenoma in cervical salivary heteropia. Handling of one case and literature review].
  • [Transliterated title] Carcinoma sobre adenoma pleomorfo en heterotopia salival cervical. Manejo de un caso y revisión de la literatura.
  • The co-existence of carcinoma expleomorphic adenoma in a salivary heterotopia in the upper third of the neck can be considered unusual.
  • We present an infrequent and clinically unsuspected case of carcinoma expleomorphic adenoma in the upper third of the neck and independent of the salivary glands.
  • [MeSH-major] Adenoma, Pleomorphic / complications. Adenoma, Pleomorphic / pathology. Carcinoma / complications. Carcinoma / pathology. Choristoma / complications. Choristoma / pathology. Salivary Gland Neoplasms / complications. Salivary Gland Neoplasms / pathology

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  • (PMID = 17949666.001).
  • [ISSN] 0001-6519
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 12
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67. Philpott CM, Kendall C, Murty GE: Canalicular adenoma of the parotid gland. J Laryngol Otol; 2005 Jan;119(1):59-60

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Canalicular adenoma of the parotid gland.
  • Canalicular adenomas are a rare form of benign tumour that occur in salivary glands, occurring mainly in the upper lip and minor salivary glands of the buccal mucosa.
  • The authors report the fifth case and the first in the otorhinolaryngological literature of a canalicular adenoma of the parotid gland.
  • [MeSH-major] Adenoma / pathology. Parotid Neoplasms / pathology

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  • (PMID = 15807970.001).
  • [ISSN] 0022-2151
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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68. Pantanowitz L: Colonic adenoma with squamous metaplasia. Int J Surg Pathol; 2009 Aug;17(4):340-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Colonic adenoma with squamous metaplasia.
  • Squamous metaplasia arising within colon adenomas is a rare occurrence, with a 0.4% incidence noted predominantly in elderly males.
  • A case of squamous metaplasia arising in a tubulovillous adenoma of the cecum, associated with adenocarcinoma, is described.
  • Squamous differentiation may serve as a precursor lesion for squamous neoplasia of the colorectum.
  • [MeSH-major] Adenoma / pathology. Colonic Neoplasms / pathology
  • [MeSH-minor] Adenocarcinoma / pathology. Aged. Biomarkers, Tumor / analysis. Colectomy. Female. Humans. Metaplasia / pathology. Metaplasia / surgery. Neoplasms, Second Primary / pathology. Precancerous Conditions / pathology. beta Catenin / analysis

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  • (PMID = 18701516.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / beta Catenin
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69. Grimm EE, Rulyak SJ, Sekijima JH, Yeh MM: Canalicular adenoma arising in the esophagus. Arch Pathol Lab Med; 2007 Oct;131(10):1595-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Canalicular adenoma arising in the esophagus.
  • Canalicular adenomas are benign neoplasms that arise from salivary glands and often present as painless enlarging nodules.
  • To our knowledge, canalicular adenoma arising in the esophagus has never been described in the English literature.
  • Here we report a canalicular adenoma occurring in the esophagus.
  • [MeSH-major] Adenoma / pathology. Esophageal Neoplasms / pathology

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  • (PMID = 17922600.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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70. Herrejón A, Cervera A, Maciá M, Ferrer R, Blanquer R: [Bronchioloalveolar adenoma associated with bronchiolitis obliterans and leishmaniasis with lung involvement in acquired immunodeficiency syndrome]. Arch Bronconeumol; 2005 Apr;41(4):233-5
HIV InSite. treatment guidelines - Human Herpesvirus-8 .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Bronchioloalveolar adenoma associated with bronchiolitis obliterans and leishmaniasis with lung involvement in acquired immunodeficiency syndrome].
  • [Transliterated title] Adenoma bronquioloalveolar asociado a bronquiolitis obliterante y leishmaniasis pulmonar en el sida.
  • In addition, the transbronchial biopsy findings were consistent with a diagnosis of bronchioloalveolar adenoma with radiographic evidence of multiple nodules.


71. Amin W, Parwani AV: Nephrogenic adenoma. Pathol Res Pract; 2010 Oct 15;206(10):659-62
The Weizmann Institute of Science GeneCards and MalaCards databases. gene/protein/disease-specific - MalaCards for nephrogenic adenoma .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nephrogenic adenoma.
  • Nephrogenic adenoma is an uncommon benign lesion.
  • The proposal that nephrogenic adenoma originates from the implantation of exfoliated renal tubular cells is lately gaining wider acceptance.
  • The role of immunohistochemistry cannot be undermined in the diagnosis of nephrogenic adenoma, although histological diagnosis is usually conclusive.
  • The possibility of nephrogenic adenoma should always be in the differential diagnosis when evaluating patients with predisposed urinary tract symptoms.
  • [MeSH-major] Adenoma / pathology. Kidney Tubules / pathology. Urologic Neoplasms / pathology
  • [MeSH-minor] Cell Transformation, Neoplastic / pathology. Diagnosis, Differential. Disease Progression. Humans. Immunohistochemistry. Predictive Value of Tests. Recurrence. Treatment Outcome. Urine / cytology

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  • [Copyright] Copyright © 2010 Elsevier GmbH. All rights reserved.
  • (PMID = 20619548.001).
  • [ISSN] 1618-0631
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
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72. Jass JR: Serrated adenoma of the colorectum and the DNA-methylator phenotype. Nat Clin Pract Oncol; 2005 Aug;2(8):398-405
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Serrated adenoma of the colorectum and the DNA-methylator phenotype.
  • Serrated adenomas (SA) of the colorectum show features intermediate between hyperplastic polyps (HP) and adenomas.
  • HP and SA are related lesions and there is now strong evidence for a 'serrated-polyp pathway' to colorectal cancer (CRC) that is largely independent of the classic adenoma-to-carcinoma sequence.
  • Because this lesion lacks the traditional cytology of colorectal adenoma and in order to avoid confusion with SA, it is referred to in this review as sessile serrated polyp.
  • [MeSH-major] Adenoma / genetics. Colonic Polyps / genetics. Colorectal Neoplasms / genetics. DNA Methylation

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  • (PMID = 16130936.001).
  • [ISSN] 1743-4254
  • [Journal-full-title] Nature clinical practice. Oncology
  • [ISO-abbreviation] Nat Clin Pract Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
  • [Number-of-references] 63
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73. Cashell AW: Apocrine adenoma of the breast. W V Med J; 2008 Mar-Apr;104(2):16-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Apocrine adenoma of the breast.
  • A case of apocrine adenoma, a rare benign tumor of the breast is reported.
  • The tumor was well circumscribed and composed of tightly packed tubules lined by cells with apocrine features.
  • Apocrine adenomas have been reported arising in a variety of sites including the breast, (1-5) perianal region, (6,7) eyelid, (8) and axilla. (9) Their appearance has similarities to the apocrine metaplasia commonly seen in fibrocystic change of the breast but they are well-circumscribed tumors with closely packed tubular and papillary structures.
  • [MeSH-major] Adenoma, Sweat Gland / diagnosis. Apocrine Glands / pathology. Breast Neoplasms / diagnosis

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  • (PMID = 18491794.001).
  • [ISSN] 0043-3284
  • [Journal-full-title] The West Virginia medical journal
  • [ISO-abbreviation] W V Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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74. Li SC, Burgart L: Histopathology of serrated adenoma, its variants, and differentiation from conventional adenomatous and hyperplastic polyps. Arch Pathol Lab Med; 2007 Mar;131(3):440-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Histopathology of serrated adenoma, its variants, and differentiation from conventional adenomatous and hyperplastic polyps.
  • CONTEXT: Serrated adenomas can be morphologically subdivided into traditional and sessile types.
  • They are thought to have a comparable rate of cancer progression like conventional adenomas, but they potentially have a faster rate of growth through methylation pathway(s).
  • They share similar morphologic features with both the conventional adenoma and the hyperplastic polyp in a fashion that is different from a mixed adenoma and a hyperplastic polyp.
  • OBJECTIVE: To describe the histopathologic features of traditional serrated adenoma and sessile serrated adenoma and their comparison with traditional adenomas and hyperplastic polyp.
  • CONCLUSIONS: Both types of serrated adenomas, traditional serrated adenoma and sessile serrated adenoma, are morphologically distinct, clinically important entities, and they can be diagnosed accurately in routine practice.
  • [MeSH-major] Adenoma / pathology. Adenomatous Polyps / pathology. Colonic Polyps / pathology. Colorectal Neoplasms / pathology

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  • (PMID = 17516746.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 15
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75. Muthukrishnan J, Verma A, Modi KD, Kumaresan K, Jha S: Ectopic parathyroid adenoma--the hidden culprit. J Assoc Physicians India; 2007 Jul;55:515-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ectopic parathyroid adenoma--the hidden culprit.
  • Primary Hyperparathyroidism is known to present with protean manifestations leading to misdiagnosis in the initial stages of the disease.
  • Inability to locate the adenoma in an ectopic parathyroid gland may further delay the diagnosis of these cases.
  • Nuclear imaging scintigraphy accurately localizes the tumor in 90% of cases and simplifies the surgical management.
  • We encountered three such cases with the parathyroid gland adenomas in ectopic locations in which pre-operative nuclear imaging played a major role.

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  • (PMID = 17907504.001).
  • [ISSN] 0004-5772
  • [Journal-full-title] The Journal of the Association of Physicians of India
  • [ISO-abbreviation] J Assoc Physicians India
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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76. Huurman VA, Schaapherder AF: Management of ruptured hepatocellular adenoma. Dig Surg; 2010;27(1):56-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Management of ruptured hepatocellular adenoma.
  • Hepatocellular adenoma (HA) is an increasingly prevalent benign liver tumor that is strongly associated with use of oral contraceptive medication.
  • Especially larger adenomas are of potential hazard to patients, because of the increased likelihood of rupture or malignant degeneration.
  • Standard treatment of larger adenomas has since long consisted in surgical resection, both for non-ruptured and for ruptured tumors.
  • Recently, newer and less invasive methods using selective transarterial embolization have been described that can successfully stop bleeding and even lead to tumor regression.
  • [MeSH-major] Adenoma, Liver Cell / therapy. Liver Neoplasms / therapy

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  • [Copyright] Copyright 2010 S. Karger AG, Basel.
  • (PMID = 20357452.001).
  • [ISSN] 1421-9883
  • [Journal-full-title] Digestive surgery
  • [ISO-abbreviation] Dig Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 29
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77. Baron TH: Ampullary adenoma. Curr Treat Options Gastroenterol; 2008 Apr;11(2):96-102

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ampullary adenoma.
  • Ampullary adenoma is a premalignant lesion involving the major papilla and surrounding mucosa of the second duodenum.
  • These lesions may arise sporadically or in the setting of familial adenomatous polyposis syndrome.
  • Ampullary adenoma may be found because of symptoms, at the time of adenomatous polyposis syndrome surveillance, or incidentally when upper endoscopy is performed for other reasons.

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  • (PMID = 18321436.001).
  • [ISSN] 1092-8472
  • [Journal-full-title] Current treatment options in gastroenterology
  • [ISO-abbreviation] Curr Treat Options Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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78. Zhang YC, Gao J, Xin T, Zheng ZM, Teng LZ: Expression of survivin in invasive pituitary adenoma. Saudi Med J; 2008 Nov;29(11):1589-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of survivin in invasive pituitary adenoma.
  • OBJECTIVE: To investigate the relationship between survivin expression and invasiveness of pituitary adenoma.
  • RESULTS: Survivin was expressed in 46 (69.7%) of the investigated pituitary adenomas.
  • For invasive pituitary adenoma, survivin staining was positive in 35 (89.7%), only 11 (40.7%) specimens were positive in noninvasive tumors.
  • The chi-square test demonstrated a statistically significant difference in survivin expression between invasive and noninvasive pituitary adenoma (chi2=14.309, p=0.0002).
  • CONCLUSION: Survivin was highly associated with invasive pituitary adenoma, it is likely to serve as a useful tool for confirmation of invasive pituitary adenoma and the gene could be an effective target for pituitary adenoma gene therapy.
  • [MeSH-major] Adenoma / metabolism. Microtubule-Associated Proteins / metabolism. Pituitary Neoplasms / metabolism

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  • (PMID = 18998006.001).
  • [ISSN] 0379-5284
  • [Journal-full-title] Saudi medical journal
  • [ISO-abbreviation] Saudi Med J
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Saudi Arabia
  • [Chemical-registry-number] 0 / BIRC5 protein, human; 0 / Inhibitor of Apoptosis Proteins; 0 / Microtubule-Associated Proteins
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79. Shibata H, Takano H, Ito M, Shioya H, Hirota M, Matsumoto H, Kakudo Y, Ishioka C, Akiyama T, Kanegae Y, Saito I, Noda T: Alpha-catenin is essential in intestinal adenoma formation. Proc Natl Acad Sci U S A; 2007 Nov 13;104(46):18199-204
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Alpha-catenin is essential in intestinal adenoma formation.
  • Although the molecular mechanism of tumor initiation is complex, several modifier genes have been identified using mouse models, including the ApcMin mouse.
  • Among the familial adenomatous polyposis mouse lines carrying a truncation mutation at codon 580 in Apc (Apc580D), one line (line19-Apc(580D/+)) showed a remarkably reduced incidence of intestinal adenomas (<5% compared with other lines).
  • In all adenomas generated in line19-Apc(580D/+), somatic recombination between the Apc and Ctnna1 loci retained the wild-type Ctnna1 allele.
  • These data strongly indicate that simultaneous inactivation of alpha-catenin and Apc during tumor initiation suppresses adenoma formation in line19-Apc(580D/+), suggesting that alpha-catenin plays an essential role in the initiation of intestinal adenomas.
  • Although accumulating evidence obtained from human colon tumors with invasive or metastatic potential has established a tumor-suppressive role for alpha-catenin in late-stage tumorigenesis, the role of alpha-catenin in the initiation of intestinal tumorigenesis is not well documented, especially compared with that of beta-catenin.
  • A mouse model used in this study focused on the early stage of tumor initiation and clearly indicated an essential role for alpha-catenin.
  • Thus, alpha-catenin has dual roles in intestinal tumorigenesis, a supporting role in tumor initiation, and a suppressive role in tumor progression.
  • [MeSH-major] Adenoma / pathology. Intestinal Neoplasms / pathology. alpha Catenin / physiology

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  • (PMID = 17989230.001).
  • [ISSN] 1091-6490
  • [Journal-full-title] Proceedings of the National Academy of Sciences of the United States of America
  • [ISO-abbreviation] Proc. Natl. Acad. Sci. U.S.A.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA Primers; 0 / alpha Catenin
  • [Other-IDs] NLM/ PMC2084320
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80. Zatelli MC, degli Uberti EC: MicroRNAs and possible role in pituitary adenoma. Semin Reprod Med; 2008 Nov;26(6):453-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] MicroRNAs and possible role in pituitary adenoma.
  • This review reports the current knowledge of microRNA (miRNA) expression in pituitary adenomas, focusing on recent microarray data.
  • Moreover, a discussion is provided concerning the possible role of validated and putative targets of the most dysregulated miRNA in pituitary adenoma pathogenesis.
  • [MeSH-major] Adenoma / genetics. MicroRNAs / physiology. Pituitary Neoplasms / genetics

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  • (PMID = 18951327.001).
  • [ISSN] 1526-4564
  • [Journal-full-title] Seminars in reproductive medicine
  • [ISO-abbreviation] Semin. Reprod. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / MicroRNAs
  • [Number-of-references] 59
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81. Bal A, Sachdeva MU, Joshi K, Behera A, Arora S, Gupta S: Non-functioning mediastinal parathyroid adenoma with sarcoid-like granulomatous lymphadenopathy. APMIS; 2007 Jun;115(6):784-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Non-functioning mediastinal parathyroid adenoma with sarcoid-like granulomatous lymphadenopathy.
  • Non-secretory parathyroid adenomas arising in an ectopic parathyroid gland are rare.
  • We report a case of non-functioning anterior mediastinal parathyroid adenoma associated with mediastinal lymphadenopathy caused by sarcoid-like granulamatous inflammation.
  • [MeSH-major] Adenoma / pathology. Lymphatic Diseases / complications. Mediastinal Neoplasms / pathology. Parathyroid Neoplasms / pathology

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  • (PMID = 17550391.001).
  • [ISSN] 0903-4641
  • [Journal-full-title] APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
  • [ISO-abbreviation] APMIS
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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82. Nitassi S, Oujilal M, Boulaich M, Essakalli L, Kzadri M: [Giant pleomorphic adenoma of the parotid gland]. Rev Stomatol Chir Maxillofac; 2009 Dec;110(6):350-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Giant pleomorphic adenoma of the parotid gland].
  • INTRODUCTION: Slow evolution pleomorphic parotid adenoma may be diagnosed late.
  • We present a case of a giant pleomorphic adenoma involving the parotid glands and try to explain the reasons for the diagnostic delay and describe therapeutic specificities.
  • The CT scan revealed a heterogeneous tumor with hyperdense and hypodense areas without any associate lesions.
  • A total conservative parotidectomy was performed; the anatomopathological examination confirmed the diagnosis of a pleomorphic adenoma, weighing 1.2kg for a diameter of 19cm, without malignant degeneration.
  • DISCUSSION: The recommended treatment for giant parotid adenoma is total conservative parotidectomy.
  • Besides its functional and esthetic impact, the giant parotid adenoma is at high risk of malignant degeneration.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Parotid Neoplasms / diagnosis

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  • (PMID = 19833364.001).
  • [ISSN] 1776-257X
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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83. López Campos D, Campos Bañales ME, López Aguado D: [Primary pleomorphic adenoma (chondroid syringoma) of the external auditory canal. Case report and literature review]. Acta Otorrinolaringol Esp; 2008 May;59(5):252-3
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  • [Title] [Primary pleomorphic adenoma (chondroid syringoma) of the external auditory canal. Case report and literature review].
  • [Transliterated title] Adenoma pleomórfico primario (siringoma condroide) del conducto auditivo externo. A propósito de un caso y revisión de la literatura.
  • Chondroid syringoma of the external auditory canal is an extremely rare neoplasm, representing the cutaneous counterpart of pleomorphic adenoma of salivary glands.
  • We report the case of a 68-year-old male in whom the clinical and radiological examinations showed a well-circumscribed tumour limited to the external auditory canal.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Ear Neoplasms / pathology. Ear, External / pathology

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  • (PMID = 18501163.001).
  • [ISSN] 0001-6519
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 12
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84. Fernandez-Ranvier GG, Khanafshar E, Jensen K, Zarnegar R, Lee J, Kebebew E, Duh QY, Clark OH: Parathyroid carcinoma, atypical parathyroid adenoma, or parathyromatosis? Cancer; 2007 Jul 15;110(2):255-64
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Parathyroid carcinoma, atypical parathyroid adenoma, or parathyromatosis?
  • BACKGROUND: Parathyroid carcinoma, atypical parathyroid adenoma, and parathyromatosis can be differentiated relatively easily from typical parathyroid adenomas, but distinguishing them from each other is more difficult.
  • METHODS: A retrospective study of 28 consecutive patients with parathyroid carcinoma, 7 patients with atypical parathyroid adenoma, and 13 patients with parathyromatosis who were treated at the University of California at San Francisco Medical Center between 1966 and 2005 was performed.
  • Patient demographics and clinical characteristics, indication for surgery, intraoperative findings, histopathologic characteristics, disease recurrence or persistence, site of invasion/metastases, and survival were compared in the 3 groups.
  • RESULTS: Parathyroid carcinoma (19 of 28 patients) and atypical adenoma (4 of 7 patients) were significantly more common in men, whereas parathyromatosis was more common in women (10 of 13 patients) (P = .02).
  • Prior to the first parathyroid surgery, patients with parathyroid carcinoma were found to have higher blood calcium levels (>/=14 mg/dL in 16 of 26 patients [62%]), whereas only 1 of 6 patients with atypical adenoma (17%) and no patients with parathyromatosis were found to have profound hypercalcemia (P < .01).
  • Intraoperatively, patients with parathyroid carcinoma and atypical adenoma presented with single lesions, whereas patients with parathyromatosis had multiple small lesions.
  • CONCLUSIONS: Patients with parathyroid carcinoma often differ from those with atypical parathyroid adenoma or parathyromatosis at the time of presentation because patients with parathyroid carcinoma have more profound hypercalcemia as well as invasive tumors.
  • [MeSH-major] Adenoma / pathology. Carcinoma / pathology. Hyperparathyroidism / pathology. Parathyroid Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Female. Humans. Male. Middle Aged. Neoplasm Metastasis. Recurrence. Retrospective Studies. Survival Analysis

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  • (PMID = 17559137.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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85. Mitchell PJ, Haboubi NY: The malignant adenoma: when to operate and when to watch. Surg Endosc; 2008 Jul;22(7):1563-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The malignant adenoma: when to operate and when to watch.
  • BACKGROUND: Adenomas are the precursors to colorectal cancer.
  • Malignant adenomas represent an early form of colorectal cancer, in which cancer has invaded by direct continuity through the muscularis mucosa into the submucosa.
  • The management of these malignant adenomas depends upon their histological risk factors and the patient's general condition.
  • METHODS: A literature review of publications regarding the malignant adenoma/polyp using Medline was performed.
  • RESULTS: The three main histological characteristics associated with an increased risk of residual disease and the potential for metastases are completeness and margin of excision, degree of differentiation and Haggitt level of invasion.
  • CONCLUSION: The dilemma as to which course of action is in the best interest of the patient with high-risk adenoma, be it either therapeutic polypectomy alone or surgical resection, is best resolved by a multidisciplinary team involving the surgeon, pathologist and endoscopist, taking the patient's condition and wishes into account.
  • [MeSH-major] Adenoma / pathology. Adenoma / surgery. Carcinoma / secondary. Cell Transformation, Neoplastic / pathology. Colorectal Neoplasms / pathology. Colorectal Neoplasms / surgery. Neoplasm, Residual / surgery
  • [MeSH-minor] Humans. Lymphatic Metastasis. Neoplasm Invasiveness. Risk Factors

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  • (PMID = 18363065.001).
  • [ISSN] 1432-2218
  • [Journal-full-title] Surgical endoscopy
  • [ISO-abbreviation] Surg Endosc
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 41
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86. Ouzounian S, Tissier F, Gouya H, Kujas M, Louvel A, Legmann P, Bertagna X: [Cushing's syndrome and adrenal adenoma. Two surprising associations]. Presse Med; 2005 Apr 09;34(7):511-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Cushing's syndrome and adrenal adenoma. Two surprising associations].
  • CASES: In the first case, we describe the case of a patient with an adrenal adenoma 20 years before the occurrence of Cushing's disease related to the pineal gland.
  • In the second case, two members of the same family were diagnosed almost simultaneously with adrenal cortical adenoma (mother) and Cushing's disease (daughter).
  • [MeSH-major] Adenoma / complications. Adrenal Gland Neoplasms / complications. Cushing Syndrome / etiology

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  • (PMID = 15903005.001).
  • [ISSN] 0755-4982
  • [Journal-full-title] Presse medicale (Paris, France : 1983)
  • [ISO-abbreviation] Presse Med
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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87. Harzallah L, Boudabbous S, Migaw H, Harzallah F, Ach K, Hamdi I, Bakir D, Chaieb L, Kraiem C: [MRI and pituitary adenoma]. Ann Endocrinol (Paris); 2006 Sep;67(4):325-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [MRI and pituitary adenoma].
  • Pituitary is the most important gland of the organism which can be affected by many diseases, especially by adenomatous processes.
  • Classically macroadenoma, microadenoma and picoadenoma are described, according to the size of the pituitary adenoma.
  • The aim of our study is to illustrate MRI features in pituitary adenoma.
  • [MeSH-major] Adenoma / diagnosis. Pituitary Neoplasms / diagnosis
  • [MeSH-minor] Humans. Magnetic Resonance Imaging / methods. Pituitary Gland / anatomy & histology. Sensitivity and Specificity

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  • (PMID = 17072237.001).
  • [ISSN] 0003-4266
  • [Journal-full-title] Annales d'endocrinologie
  • [ISO-abbreviation] Ann. Endocrinol. (Paris)
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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88. Vieth M, Vogel C, Kushima R, Borchard F, Stolte M: Pyloric gland adenoma-- how to diagnose? Cesk Patol; 2006 Jan;42(1):4-7
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  • [Title] Pyloric gland adenoma-- how to diagnose?
  • The term "pyloric gland adenoma" reflects its etiogenesis from deep mucoid glands in the stomach.
  • Typically, pyloric gland adenomas are strongly positive for Mucin 6 (deep mucoid gastric glands).
  • Combination or transdifferentiation with ordinary tubular (intestinal differentiation) adenoma can be observed.
  • The frequency of pyloric gland adenoma is given in the literature being 2.7% of all gastric polyps.
  • Therefore pyloric gland adenomas are not that rare that one might assume.
  • Pyloric gland adenomas can arise in gastric heterotopia and gastric metaplasia in the whole gastrointestinal tract.
  • [MeSH-major] Adenoma / diagnosis. Gastric Mucosa. Stomach Neoplasms / diagnosis

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  • (PMID = 16506593.001).
  • [ISSN] 1210-7875
  • [Journal-full-title] Československá patologie
  • [ISO-abbreviation] Cesk Patol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Czech Republic
  • [Chemical-registry-number] 0 / Mucins
  • [Number-of-references] 24
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89. Eckardt AJ, Swales C, Bhattacharya K, Wassef WY, Leung K, Levey JM: Does trainee participation during colonoscopy affect adenoma detection rates? Dis Colon Rectum; 2009 Jul;52(7):1337-44
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Does trainee participation during colonoscopy affect adenoma detection rates?
  • It remains unknown whether adenoma detection rates are adversely affected by trainee participation.
  • The primary aim of this study was to investigate whether adenoma detection rates differed between procedures with or without trainee involvement.
  • RESULTS: Adenomas were detected in 19.3% of experienced physician-only procedures and in 14.9% of procedures with trainee participation.
  • Advanced adenomas were detected in 8.6% of experienced physicians' procedures vs. 4.9% of trainee procedures.
  • CONCLUSION: Adenoma detection rates did not differ significantly, whether there was trainee involvement or not.
  • A trend toward finding more adenomas or advanced adenomas in the absence of a trainee was observed, but it was lower than previously reported interobserver variability among experienced physicians.
  • The small difference in adenoma detection was not observed for polyp detection, which may be explained by the more frequent removal of hyperplastic polyps by trainees.
  • [MeSH-major] Adenoma / diagnosis. Clinical Competence. Colonic Neoplasms / diagnosis. Colonic Polyps / diagnosis. Colonoscopy. Diagnostic Errors

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  • (PMID = 19571713.001).
  • [ISSN] 1530-0358
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Controlled Clinical Trial; Journal Article
  • [Publication-country] United States
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90. Colović R, Grubor N, Radak V, Micev M, Colović N, Stojković M: [Tubular adenoma of the gallbladder with squamous metaplasia]. Srp Arh Celok Lek; 2006 Mar-Apr;134(3-4):159-61
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  • [Title] [Tubular adenoma of the gallbladder with squamous metaplasia].
  • Adenomas of the gallbladder are rare tumors.
  • Tubular adenoma appears in middle aged and older patients, although it may develop even in children.
  • Histology showed tubular adenoma with mild epithelial dysplasia in some places and with antral and squamous metaplasia.
  • [MeSH-major] Adenoma / pathology. Gallbladder Neoplasms / pathology

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  • (PMID = 16915759.001).
  • [ISSN] 0370-8179
  • [Journal-full-title] Srpski arhiv za celokupno lekarstvo
  • [ISO-abbreviation] Srp Arh Celok Lek
  • [Language] srp
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Serbia and Montenegro
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91. Noh SJ, Ahn JY, Lee KS, Kim SH: Pituitary adenoma and concomitant Rathke's cleft cyst. Acta Neurochir (Wien); 2007 Dec;149(12):1223-8
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  • [Title] Pituitary adenoma and concomitant Rathke's cleft cyst.
  • Although pituitary adenomas and Rathke's cleft cysts have a shared ancestry, they rarely occur simultaneously.
  • Only 32 reports involving a pituitary adenoma and a concomitant Rathke's cleft cyst were identified upon review of the literature.
  • Here, we report a patient with a growth hormone- secreting pituitary adenoma associated with a Rathke's cleft cyst.
  • When a non-enhancing cyst-like structure is demonstrated on imaging in a patient with a pituitary adenoma, the possibility of a coexisting Rathke's cleft cyst should be considered.
  • [MeSH-major] Adenoma / surgery. Central Nervous System Cysts / surgery. Growth Hormone-Secreting Pituitary Adenoma / surgery. Neoplasms, Multiple Primary / surgery. Pituitary Neoplasms / surgery
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Image Processing, Computer-Assisted. Magnetic Resonance Imaging. Middle Aged. Neuronavigation. Pituitary Gland / pathology

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  • (PMID = 17914599.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Austria
  • [Number-of-references] 28
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92. El Fakiri MM, Aderdour L, Nouri H, Hassani R, Maliki O, Raji A: [Pleomorphic adenoma of the nasal septum]. Rev Stomatol Chir Maxillofac; 2010 Jun;111(3):162-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pleomorphic adenoma of the nasal septum].
  • INTRODUCTION: The pleomorphic adenoma is the most common benign neoplasm of primary salivary glands.
  • We report a case of pleomorphic adenoma of the nasal septum.
  • A facial CT-scan showed a heterogeneous tumor of the nasal septum obstructing the left nasal vestibule.
  • The biopsy analysis proved the histological characteristics of a pleomorphic adenoma, and was further confirmed by immunohistochemical study.
  • DISCUSSION: The treatment of nasal pleomorphic adenomas must take into account lesion localization, esthetic complications, and evolutionary potential of the lesions.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Nasal Septum / pathology. Nose Neoplasms / diagnosis

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  • [Copyright] Copyright 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20416914.001).
  • [ISSN] 1776-257X
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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93. Agurs-Collins T, Smoot D, Afful J, Makambi K, Adams-Campbell LL: Legume intake and reduced colorectal adenoma risk in African-Americans. J Natl Black Nurses Assoc; 2006 Dec;17(2):6-12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Legume intake and reduced colorectal adenoma risk in African-Americans.
  • Colorectal adenomas are known precursors for colorectal cancer.
  • Several studies have shown that dietary factors can influence adenoma formation and growth.
  • A multiple logistic regression model was used to adjust for potential confounding variables and to determine which factors influence colorectal adenoma risk.
  • Legumes are a good source of dietary fiber and of phytochemical compounds that may play a role in reducing adenoma formation or growth, thereby decreasing the risk of colorectal cancer.
  • [MeSH-major] Adenomatous Polyps. African Americans / ethnology. Colorectal Neoplasms. Fabaceae. Food Habits / ethnology

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  • (PMID = 17410754.001).
  • [ISSN] 0885-6028
  • [Journal-full-title] Journal of National Black Nurses' Association : JNBNA
  • [ISO-abbreviation] J Natl Black Nurses Assoc
  • [Language] eng
  • [Grant] United States / NCRR NIH HHS / RR / M01-RR10284
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
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94. Wang H, Li W, Shi D, Ye Z, Qin F, Guo Y, Yuan X: Expression of TGFbeta1 and pituitary adenoma fibrosis. Br J Neurosurg; 2009 Jun;23(3):293-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of TGFbeta1 and pituitary adenoma fibrosis.
  • Transsphenoidal approach has been increasingly used in the resection of pituitary adenomas for its minimal invasiveness.
  • However, in about 10% of these cases, the tumor cannot be totally removed due to the fibrosis.
  • In this work, the object is to study the relationship between expression of transforming growth factor beta1 (TGFbeta1) and fibrosis of pituitary adenoma.
  • 38 pituitary adenoma specimens were divided into fibrous group (6 cases) and non-fibrous group (32 cases).
  • Collagen deposition is a significant pathological feature in fibrous pituitary adenomas.
  • TGFbeta1 may play an important role in the fibrosis of adenoma.
  • [MeSH-major] Adenoma. Neoplasm Proteins / metabolism. Peptide Fragments / metabolism. Pituitary Gland / pathology. Pituitary Neoplasms. Transforming Growth Factor beta1 / metabolism

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  • (PMID = 19533462.001).
  • [ISSN] 1360-046X
  • [Journal-full-title] British journal of neurosurgery
  • [ISO-abbreviation] Br J Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Neoplasm Proteins; 0 / Peptide Fragments; 0 / Transforming Growth Factor beta1; 0 / transforming growth factor beta1 (41-65); 9007-34-5 / Collagen
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95. Azevedo RS, Almeida OP, Netto JN, Miranda AM, Santos TC, Della Coletta R, Lopes MA, Pires FR: Comparative clinicopathological study of intraoral sebaceous hyperplasia and sebaceous adenoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2009 Jan;107(1):100-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comparative clinicopathological study of intraoral sebaceous hyperplasia and sebaceous adenoma.
  • OBJECTIVE: The objective of this study was to compare the clinicopathological features of oral sebaceous hyperplasia and sebaceous adenoma.
  • STUDY DESIGN: Clinical data, microscopical characteristics, and ki-67 immunoexpression were comparatively analyzed on 2 intraoral sebaceous adenomas, 6 intraoral sebaceous hyperplasias, and 21 normal intraoral sebaceous glands.
  • RESULTS: Clinically, sebaceous glands presented as multiple separated papules, sebaceous hyperplasias as a single enlarged papule, and sebaceous adenoma as a well-defined nodule.
  • Microscopically, sebaceous adenoma presented an increased number of lobules, smaller lobules, and a greater number of germinative/squamous cells.
  • Ki-67 expression was seen only in germinative cells and counts were higher in sebaceous adenomas followed by hyperplasias and normal glands.
  • CONCLUSIONS: Sebaceous hyperplasias and adenomas showed different clinical, microscopic, and proliferative characteristics, suggesting the usefulness of the studied criteria on diagnosis of these uncommon oral lesions.
  • [MeSH-major] Adenoma / pathology. Mouth Neoplasms / pathology. Sebaceous Gland Diseases / pathology. Sebaceous Gland Neoplasms / pathology. Sebaceous Glands / pathology

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  • (PMID = 19101492.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Ki-67 Antigen
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96. Castelo-Branco C, del Pino M, Valladares E: Ovarian hyperstimulation, hyperprolactinaemia and LH gonadotroph adenoma. Reprod Biomed Online; 2009 Aug;19(2):153-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ovarian hyperstimulation, hyperprolactinaemia and LH gonadotroph adenoma.
  • This report considers a highly exceptional case of ovarian hyperstimulation syndrome due to a gonadotroph adenoma secreting LH in a 31-year-old patient who presented with amenorrhoea and galactorrhoea syndrome and a complex bilateral ovarian mass.
  • Magnetic resonance imaging revealed a pituitary adenoma, and laboratory tests corroborated the hyperprolactinaemia without other hormonal pituitary abnormalities.
  • Ovarian hyperstimulation syndrome due to a gonadotroph adenoma with normal gonadotrophins is extremely rare.
  • Most of the described cases are caused by FSH adenomas.
  • Due to the originality of the case, it was considered useful for understanding the management of this entity, and it is proposed that LH adenomas should also be considered in the differential diagnosis of patients with spontaneous ovarian hyperstimulation syndrome.
  • [MeSH-major] Adenoma / complications. Hyperprolactinemia / complications. Luteinizing Hormone / secretion. Ovarian Hyperstimulation Syndrome / complications. Pituitary Neoplasms / complications

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  • (PMID = 19712547.001).
  • [ISSN] 1472-6491
  • [Journal-full-title] Reproductive biomedicine online
  • [ISO-abbreviation] Reprod. Biomed. Online
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 9002-67-9 / Luteinizing Hormone
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97. Gosse P, Guiheneuf-Tobie C, Lasserre R, Minifie C, Lemetayer P, Clementy J: [Biochemical detection of Conn's adenoma: definition of criteria and reference values]. Arch Mal Coeur Vaiss; 2005 Mar;98(3):181-5
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  • [Title] [Biochemical detection of Conn's adenoma: definition of criteria and reference values].
  • In this study we evaluated the defined reference values prospectively by studying a population of patients with a Conn's adenoma treated surgically.
  • The study included an initial retrospective period which allowed identification of 29 cases of Conn's adenoma treated surgically, and a 9 month prospective period during which 212 reports were collected.
  • During this prospective period a further 9 cases of Conn's adenoma were detected, which were successfully treated with surgery.
  • [MeSH-major] Adenoma / diagnosis. Adrenal Gland Neoplasms / diagnosis. Hyperaldosteronism / diagnosis

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  • (PMID = 15816319.001).
  • [ISSN] 0003-9683
  • [Journal-full-title] Archives des maladies du coeur et des vaisseaux
  • [ISO-abbreviation] Arch Mal Coeur Vaiss
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 4964P6T9RB / Aldosterone; EC 3.4.23.15 / Renin
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98. Hemminki K, Försti A, Ji J: Incidence and familial risks in pituitary adenoma and associated tumors. Endocr Relat Cancer; 2007 Mar;14(1):103-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Incidence and familial risks in pituitary adenoma and associated tumors.
  • We wanted to study incidence trends and familial risks for pituitary adenomas and associated tumors through parental and sibling probands, using the nation-wide Swedish Family-Cancer Database on 10.5 million individuals, containing families with parents and offspring.
  • Cancer data were retrieved from the Swedish Cancer Registry from years 1958 to 2002, including 3239 pituitary tumor patients.
  • The incidence of pituitary adenoma has increased moderately from 1958 to the 1990s and declined thereafter.
  • There were only three offspring-parent pairs with a concordant pituitary tumor, the SIR was not significant.
  • Parental skin cancer (SIR 1.60) and leukemia (1.90, chronic lymphatic leukemia 2.59) were associated with offspring pituitary adenoma diagnosed at any age up to 70 years.
  • There was a strong association of pituitary adenomas with nervous system hemangiopericytomas, SIR 182.
  • The risk of pituitary adenoma was marginally increased in individuals whose siblings were diagnosed with colorectal cancer.
  • The results suggest an association of pituitary adenomas with nervous system hemangiopericytomas and breast and colorectal cancers, in addition to some other tumor types.
  • Whether these associations can be explained by the recently identified pituitary adenoma predisposing gene, AIP, remains to be established.
  • [MeSH-major] Adenoma / epidemiology. Genetic Predisposition to Disease. Pituitary Neoplasms / epidemiology

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  • (PMID = 17395979.001).
  • [ISSN] 1351-0088
  • [Journal-full-title] Endocrine-related cancer
  • [ISO-abbreviation] Endocr. Relat. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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99. Renshaw AA, Kish R, Gould EW: Sessile serrated adenoma is associated with acute appendicitis in patients 30 years or older. Am J Clin Pathol; 2006 Dec;126(6):875-7
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  • [Title] Sessile serrated adenoma is associated with acute appendicitis in patients 30 years or older.
  • Sessile serrated adenoma is a relatively recently described entity that can occur in the appendix.
  • The incidence of this finding is unknown.
  • In cases submitted routinely, only 1 sessile serrated adenoma was found.
  • In contrast, in cases entirely submitted, 11 adenomas were found, all in patients 30 years or older.
  • All sessile serrated adenomas were present in 3 cross-sections or fewer of the appendix.
  • The incidence of sessile serrated adenoma in patients with acute appendicitis is significantly increased in patients 30 years or older (P = .001), and detection is dependent on thorough tissue sampling.
  • [MeSH-major] Adenoma / pathology. Appendiceal Neoplasms / pathology. Appendicitis / pathology
  • [MeSH-minor] Acute Disease. Adult. Age Factors. Appendectomy. Humans

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  • (PMID = 17074693.001).
  • [ISSN] 0002-9173
  • [Journal-full-title] American journal of clinical pathology
  • [ISO-abbreviation] Am. J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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100. Wu WX, Duan YY, Lü GH, Shi SF, Zhang JY, Wang HS, Zhang XH: [Expression and significance of JNK1, Raf-1 and Livin in the carcinogenesis of sporadic colorectal tubular adenoma]. Zhonghua Zhong Liu Za Zhi; 2010 Sep;32(9):671-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Expression and significance of JNK1, Raf-1 and Livin in the carcinogenesis of sporadic colorectal tubular adenoma].
  • OBJECTIVE: To study the possible role of JNK1, Raf-1 and Livin in the carcinogenesis of sporadic colorectal tubular adenoma.
  • METHODS: Immunohistochemical staining was used to detect the expression of JNK1, Raf-1 and Livin proteins in 65 sporadic colorectal tubular adenomas with dysplasia of varying degrees and 22 colorectal tubular adenoma with cancerous area.
  • RESULTS: In normal colorectal mucosa, colorectal tubular adenoma with dysplasia and colorectal tubular adenoma with cancerous area, the positive rate of JNK1, Raf-1 and Livin expression was increased gradually.
  • The positive expression of JNK1, Raf-1 and Livin was all significantly higher in the cases of colorectal tubular adenoma with dysplasia or with cancerous area than that in normal colorectal mucosa (P < 0.05), and the positive expression of JNK1, Raf-1 and Livin was significantly higher in colorectal tubular adenoma with cancerous area than that in colorectal tubular adenoma with dysplasia of different degrees (P < 0.05).
  • In the cases of colorectal tubular adenoma with dysplasia of varying degrees, the positive expression of Raf-1 was increased along with the increasing dysplasia degree of colorectal tubular adenoma (P < 0.05).
  • Coexpression of JNK1, Raf-1 and Livin increased gradually in the carcinogenesis of sporadic colorectal tubular adenoma, while positive correlation was found among the expressions of JNK1, Raf-1 and Livin.
  • CONCLUSION: JNK1, Raf-1 and Livin may be involved in the carcinogenesis of sporadic colorectal tubular adenoma.
  • [MeSH-major] Adaptor Proteins, Signal Transducing / metabolism. Adenoma / pathology. Cell Transformation, Neoplastic. Colorectal Neoplasms / pathology. Inhibitor of Apoptosis Proteins / metabolism. Mitogen-Activated Protein Kinase 8 / metabolism. Neoplasm Proteins / metabolism. Proto-Oncogene Proteins c-raf / metabolism

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  • (PMID = 21122381.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Adaptor Proteins, Signal Transducing; 0 / BIRC7 protein, human; 0 / Inhibitor of Apoptosis Proteins; 0 / Neoplasm Proteins; EC 2.7.11.1 / Proto-Oncogene Proteins c-raf; EC 2.7.11.24 / Mitogen-Activated Protein Kinase 8
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