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1. Schapher M, Wendler O, Gröschl M, Schäfer R, Iro H, Zenk J: Salivary leptin as a candidate diagnostic marker in salivary gland tumors. Clin Chem; 2009 May;55(5):914-22
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  • [Title] Salivary leptin as a candidate diagnostic marker in salivary gland tumors.
  • BACKGROUND: Since the discovery of autonomous leptin production in salivary glands, very few studies have reported on the physiological or pathological meaning of this particular cytokine in saliva.
  • The aim of this study was to investigate the expression of leptin and its receptors Ob-Ra and Ob-Rb in parotid salivary gland tumors, with particular regard to a potential use of leptin as a tumor marker.
  • Salivary and plasma leptin concentrations were measured by using ELISA.
  • RESULTS: In all salivary gland tumors leptin was expressed in much higher amounts than in healthy parotid tissues.
  • Immunoblotting results indicated that leptin was present as oligomers in salivary glands.
  • CONCLUSIONS: This is the first study to show that the analysis of salivary leptin in mixed saliva samples may allow preoperative differentiation between tumor patients and healthy individuals.
  • [MeSH-minor] Adenolymphoma / diagnosis. Adenolymphoma / metabolism. Adenolymphoma / pathology. Adenoma, Pleomorphic / diagnosis. Adenoma, Pleomorphic / metabolism. Adenoma, Pleomorphic / pathology. Adiponectin / biosynthesis. Adiponectin / genetics. Adolescent. Adult. Aged. Aged, 80 and over. Blotting, Western. Enzyme-Linked Immunosorbent Assay. Female. Fluorescent Antibody Technique, Indirect. Humans. Immunohistochemistry. Male. Middle Aged. Polymerase Chain Reaction. RNA, Messenger / biosynthesis. RNA, Messenger / genetics. Receptors, Leptin / biosynthesis. Receptors, Leptin / genetics. Young Adult

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  • (PMID = 19299541.001).
  • [ISSN] 1530-8561
  • [Journal-full-title] Clinical chemistry
  • [ISO-abbreviation] Clin. Chem.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / ADIPOQ protein, human; 0 / Adiponectin; 0 / Biomarkers, Tumor; 0 / Leptin; 0 / RNA, Messenger; 0 / Receptors, Leptin; 0 / leptin receptor, human
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2. Gallipoli A, Manganella G, De Lutiodi di Castelguidone E, Mastro A, Ionna F, Pezzullo L, Vallone P: Ultrasound contrast media in the study of salivary gland tumors. Anticancer Res; 2005 May-Jun;25(3c):2477-82
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  • [Title] Ultrasound contrast media in the study of salivary gland tumors.
  • BACKGROUND: The aims of the present study were: to assess standard ultrasound and color-Doppler patterns for the study and characterization of salivary gland tumors; to define the improvement in the color-Doppler ultrasound image after injection of a signal amplifier (Levovist); to compare morphological and vascular aspects of the neoplasm with data obtained during postoperative histopathological analysis.
  • MATERIALS AND METHODS: We used color-Doppler ultrasound before and after injection of the contrast medium to study 56 patients (32 males and 24 females) between the ages of 28 and 77 years old, presenting nodular pathology of the salivary glands.
  • CONCLUSION: We observed that the contrast medium was useful in characterizing lesions, of the salivary glands by allowing for a more precise vascular map of the lesions, as well as greater diagnostic accuracy in tracing the vascular blood flow and calculating quantitative and semiquantitative data.
  • [MeSH-major] Salivary Gland Neoplasms / ultrasonography. Ultrasonography, Doppler, Color / methods
  • [MeSH-minor] Adenolymphoma / ultrasonography. Adenoma, Pleomorphic / ultrasonography. Adult. Aged. Carcinoma / ultrasonography. Contrast Media. Female. Humans. Lipoma / ultrasonography. Male. Middle Aged

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  • (PMID = 16080479.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Contrast Media
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3. Ellis GL: Lymphoid lesions of salivary glands: malignant and benign. Med Oral Patol Oral Cir Bucal; 2007 Dec;12(7):E479-85
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  • [Title] Lymphoid lesions of salivary glands: malignant and benign.
  • Lesions of salivary glands with a prominent lymphoid component are a heterogeneous group of diseases that include benign reactive lesions and malignant neoplasms.
  • Occasionally, these pathologic entities present difficulties in the clinical and pathological diagnosis and prognosis.
  • Lymphoepithelial sialadenitis, HIV-associated salivary gland disease, chronic sclerosing sialadenitis, Warthin tumor, and extranodal marginal zone B-cell lymphoma are examples of this pathology that are sometimes problematic to differentiate from one another.
  • [MeSH-major] Salivary Gland Diseases. Salivary Gland Neoplasms
  • [MeSH-minor] Adenolymphoma / diagnosis. Carcinoma / diagnosis. Humans. Lymphoma, B-Cell, Marginal Zone / diagnosis. Prognosis. Sialadenitis / diagnosis

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  • (PMID = 17978770.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 30
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4. Maffini F, Fasani R, Petrella D, Maiorano E, Bruschini R, Pelosi G, Viale G: Sebaceous lymphadenoma of salivary gland: a case report and a review of the literature. Acta Otorhinolaryngol Ital; 2007 Jun;27(3):147-50
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  • [Title] Sebaceous lymphadenoma of salivary gland: a case report and a review of the literature.
  • The unusual case is described of a benign parotid gland neoplasm with intermingled sebaceous and lymphoid tissue, synchronous to breast cancer.
  • In the past, the patient had undergone a simple surgical procedure for a cystic parotid gland lesion in that same gland.
  • Secondary neoplasms have only occasionally been reported, since there are few cases for corroborating the strong correlation between salivary neoplasms and other carcinomas as in Muir-Torre syndrome; the previous cystic lesion showed the origin of the neoplasm from a sebaceous inclusion in the lymph node as a postulate of Warthin tumour.
  • [MeSH-major] Adenolymphoma / pathology. Salivary Gland Neoplasms / pathology. Sebaceous Gland Neoplasms / pathology
  • [MeSH-minor] Aged. Diagnosis, Differential. Female. Humans. Neoplasm Invasiveness / pathology

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  • (PMID = 17883194.001).
  • [ISSN] 0392-100X
  • [Journal-full-title] Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale
  • [ISO-abbreviation] Acta Otorhinolaryngol Ital
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 31
  • [Other-IDs] NLM/ PMC2640041
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5. Halimi P, Gardner M, Petit F: [Tumors of the salivary glands]. Cancer Radiother; 2005 Jun;9(4):251-60
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  • [Title] [Tumors of the salivary glands].
  • Tumors of salivary glands arise mainly from the parotid gland.
  • Magnetic Resonance Imaging (MRI) is mandatory not only to localize precisely the tumor within the gland but also to differentiate between benign and malignant neoplasms, in competition with cytology in fine-needle aspiration biopsy.
  • Tumors without risk of transformation, such as adenolymphoma, are not systematically operated on.
  • [MeSH-major] Adenolymphoma / pathology. Adenolymphoma / radiotherapy. Salivary Gland Neoplasms / pathology. Salivary Gland Neoplasms / radiotherapy
  • [MeSH-minor] Biopsy, Needle. Diagnosis, Differential. Humans. Magnetic Resonance Imaging

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  • (PMID = 16019247.001).
  • [ISSN] 1278-3218
  • [Journal-full-title] Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
  • [ISO-abbreviation] Cancer Radiother
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 37
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6. Mortensen KS, Hjortlund J, Bjørndal K, Krogdal A, Godballe C: [Salivary gland tumors in the County of Funen, 1984-2003]. Ugeskr Laeger; 2008 Feb 11;170(7):545-8
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  • [Title] [Salivary gland tumors in the County of Funen, 1984-2003].
  • INTRODUCTION: The objective of this study is to estimate the incidence of major salivary gland tumors in a geographically well-defined area (the County of Funen, Denmark) and to analyse the demographic data and distribution of histological types.
  • MATERIALS AND METHODS: Patients with salivary gland tumors were identified through a search on pathology and diagnosis codes in the period 1984-2003, which initially resulted in a group of 951 patients.
  • RESULTS: The incidence of major salivary gland tumors for the County of Funen is calculated to 7.3 per 100,000 residents per year.
  • Pleomorphic adenoma (55%) was the most common type, followed by adenolymphoma (29%).
  • 90% of the tumors were found in the parotid gland - 93% benign and 7% malignant.
  • 10% were located in the submandibular gland - 73% benign and 27% malignant.
  • Only one neoplasm was located in the sublingual gland and it was malignant (100%).
  • CONCLUSION: The incidence of major salivary gland tumors in the County of Funen is calculated to 7.3 per 100,000 inhabitants per year which is equivalent to 383 new cases in Denmark per year.
  • [MeSH-major] Adenolymphoma / epidemiology. Adenoma, Pleomorphic / epidemiology. Salivary Gland Neoplasms / epidemiology

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  • (PMID = 18291086.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Denmark
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7. Chikui T, Tokumori K, Yoshiura K, Oobu K, Nakamura S, Nakamura K: Sonographic texture characterization of salivary gland tumors by fractal analyses. Ultrasound Med Biol; 2005 Oct;31(10):1297-304
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  • [Title] Sonographic texture characterization of salivary gland tumors by fractal analyses.
  • The purpose of this study was to quantify the sonographic images of salivary gland tumors.
  • [MeSH-major] Adenoma / ultrasonography. Carcinoma / ultrasonography. Fractals. Image Interpretation, Computer-Assisted. Neoplasms, Multiple Primary / ultrasonography. Salivary Gland Neoplasms / ultrasonography
  • [MeSH-minor] Adenolymphoma / ultrasonography. Adenoma, Pleomorphic / ultrasonography. Diagnosis, Differential. Humans. Imaging, Three-Dimensional. Parotid Neoplasms / ultrasonography. Salivary Glands / ultrasonography. Submandibular Gland Neoplasms / ultrasonography

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  • (PMID = 16223632.001).
  • [ISSN] 0301-5629
  • [Journal-full-title] Ultrasound in medicine & biology
  • [ISO-abbreviation] Ultrasound Med Biol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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8. Párraga-Linares L, Aguirre-Urízar JM, Berini-Aytés L, Gay-Escoda C: Papillary cystoadenoma lymphomatosum (Warthin-like) of minor salivary glands. Med Oral Patol Oral Cir Bucal; 2009 Nov;14(11):e597-600
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  • [Title] Papillary cystoadenoma lymphomatosum (Warthin-like) of minor salivary glands.
  • Papillary cystadenoma lymphomatosum is a benign salivary gland tumor most frequently located in the parotid gland (Warthin's tumor).
  • Its presentation in other major, or in minor, salivary glands is rare.
  • [MeSH-major] Adenolymphoma / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands, Minor / pathology

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  • (PMID = 19680204.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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9. Mahy P, Reychler H: [The pathology of salivary glands. Tumors of the salivary glands]. Rev Belge Med Dent (1984); 2006;61(3):141-53
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  • [Title] [The pathology of salivary glands. Tumors of the salivary glands].
  • The management of benign and malignant neoplasms of the salivary glands requires precise knowledge of tumor histogenesis and classification as well as surgical skills.
  • Pleomorphic adenoma and Whartin's tumor are the most frequent tumors in parotid glands while the probability for malignant tumors is higher in other glands, especially in sublingual and minor salivary glands.
  • Those malignant salivary glands tumors are rare and necessitate multidisciplinar staging and management in close collaboration with the pathologist and the radiation oncologist.
  • [MeSH-major] Salivary Gland Neoplasms / surgery
  • [MeSH-minor] Adenolymphoma / pathology. Adenoma, Pleomorphic / pathology. Humans. Neoplasm Staging. Prognosis. Radiotherapy, Adjuvant. Salivary Glands, Minor / pathology. Sublingual Gland Neoplasms / pathology

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  • (PMID = 17408135.001).
  • [ISSN] 0775-0293
  • [Journal-full-title] Revue belge de médecine dentaire
  • [ISO-abbreviation] Rev Belge Med Dent (1984)
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Belgium
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10. Andreadis D, Epivatianos A, Mireas G, Nomikos A, Poulopoulos A, Yiotakis J, Barbatis C: Immunohistochemical detection of E-cadherin in certain types of salivary gland tumours. J Laryngol Otol; 2006 Apr;120(4):298-304
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  • [Title] Immunohistochemical detection of E-cadherin in certain types of salivary gland tumours.
  • OBJECTIVES: To investigate the topography of E-cadherin and its possible correlation with the histological phenotype of salivary gland tumours.
  • MATERIAL AND METHODS: Archival formalin-fixed, paraffin-embedded sections of 54 benign and 56 malignant tumours and 24 samples of normal and inflamed salivary gland tissue were studied immunohistochemically using an Envision/horseraddish peroxidase (HRP) technique.
  • RESULTS: In normal and inflamed salivary gland samples, E-cadherin was expressed at the membrane of acinar, myoepithelial and ductal cells located at cell-cell contact points.
  • Moderate to extreme loss or alternative cytoplasmic non-functional expression were observed in cases of salivary ductal carcinoma, carcinosarcoma, myoepithelial carcinoma, oncocytic adenocarcinoma, unspecified adenocarcinoma and squamous high-grade carcinomas.
  • CONCLUSION: This study suggests a direct association of E-cadherin expression with neoplastic histologic phenotype, which is lost in the more undifferentiated and invasive epithelial salivary gland tumours.
  • [MeSH-major] Adenocarcinoma / chemistry. Biomarkers, Tumor / analysis. Cadherins / analysis. Carcinoma, Adenoid Cystic / chemistry. Carcinoma, Ductal / chemistry. Salivary Gland Neoplasms / metabolism
  • [MeSH-minor] Adenolymphoma / chemistry. Adenoma / chemistry. Adenoma, Pleomorphic / chemistry. Humans. Immunohistochemistry / methods. Salivary Gland Diseases / metabolism. Salivary Glands / chemistry

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  • (PMID = 16623973.001).
  • [ISSN] 0022-2151
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Cadherins
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11. Salama AR, Ord RA: Clinical implications of the neck in salivary gland disease. Oral Maxillofac Surg Clin North Am; 2008 Aug;20(3):445-58
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  • [Title] Clinical implications of the neck in salivary gland disease.
  • Neck manifestations from salivary gland tissue are most commonly related to inflammation and obstruction of the glands.
  • [MeSH-major] Neck / surgery. Salivary Gland Diseases / diagnosis. Salivary Gland Diseases / surgery. Salivary Gland Neoplasms / diagnosis. Salivary Gland Neoplasms / surgery
  • [MeSH-minor] Adenolymphoma / diagnosis. Adenolymphoma / surgery. Adenoma, Pleomorphic / diagnosis. Adenoma, Pleomorphic / surgery. Carcinoma / diagnosis. Carcinoma / secondary. Carcinoma / surgery. Carcinosarcoma / diagnosis. Carcinosarcoma / secondary. Carcinosarcoma / surgery. Choristoma / diagnosis. Choristoma / surgery. Humans. Lymphatic Metastasis. Neck Dissection. Parotid Neoplasms / diagnosis. Parotid Neoplasms / surgery. Ranula / diagnosis. Ranula / surgery. Submandibular Gland Neoplasms / diagnosis. Submandibular Gland Neoplasms / surgery

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  • (PMID = 18603202.001).
  • [ISSN] 1558-1365
  • [Journal-full-title] Oral and maxillofacial surgery clinics of North America
  • [ISO-abbreviation] Oral Maxillofac Surg Clin North Am
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 89
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12. Jones AV, Craig GT, Speight PM, Franklin CD: The range and demographics of salivary gland tumours diagnosed in a UK population. Oral Oncol; 2008 Apr;44(4):407-17
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  • [Title] The range and demographics of salivary gland tumours diagnosed in a UK population.
  • Salivary gland tumours are relatively rare and comprise a diverse range of neoplasms.
  • The aim of this study was to determine the range and demographics of all histologically diagnosed salivary tumours in a European population.
  • All entries for salivary gland tumours from 1974 to 2005 inclusive were retrieved and analysed for each diagnosis including number of specimens, male:female ratio and age range.
  • These data were then analysed for the distribution of benign and malignant salivary tumours in major and minor salivary glands.
  • 58,880 specimens were received; of these, 741 cases (1.3% of all specimens) were diagnosed as salivary gland tumours with a male to female ratio of 0.7:1.
  • Our study provides demographic data on a large series of salivary gland tumours in a European population.
  • Accurate diagnosis is essential as salivary lesions have diverse clinical and prognostic outcomes.
  • [MeSH-major] Salivary Gland Neoplasms / epidemiology
  • [MeSH-minor] Adenolymphoma / epidemiology. Adenolymphoma / pathology. Adenoma / epidemiology. Adenoma / pathology. Adenoma, Pleomorphic / epidemiology. Adenoma, Pleomorphic / pathology. Adolescent. Adult. Age Distribution. Aged. Aged, 80 and over. Carcinoma, Mucoepidermoid / epidemiology. Carcinoma, Mucoepidermoid / pathology. Child. England / epidemiology. Female. Humans. Male. Middle Aged. Salivary Glands, Minor. Sex Distribution

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  • (PMID = 17825603.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] England
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13. Li LJ, Li Y, Wen YM, Liu H, Zhao HW: Clinical analysis of salivary gland tumor cases in West China in past 50 years. Oral Oncol; 2008 Feb;44(2):187-92
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  • [Title] Clinical analysis of salivary gland tumor cases in West China in past 50 years.
  • In our study, 3461 cases of salivary gland tumor treated between 1955 and 2002 at West China Stomatology Hospital of Sichuan University were retrospectively analyzed, and compared with the previous reports.
  • The findings are as follows: the average ages of salivary gland tumor patients were 41.38 years for the benign cases and 45.20 for the malignant ones; the male:female ratio was 0.
  • 99:1 in the benign cases and 1.34:1 in the malignant ones; primary tumors were mostly in the parotid gland, palate and submandibular gland in sequence.
  • The incidence of salivary gland tumors increased with age.
  • The parotid gland and palate were the most common locations of salivary gland tumors.
  • [MeSH-major] Adenoma, Pleomorphic / epidemiology. Carcinoma, Mucoepidermoid / epidemiology. Salivary Gland Neoplasms / epidemiology
  • [MeSH-minor] Adenocarcinoma / pathology. Adenolymphoma / pathology. Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Adenoid Cystic / pathology. Child. Child, Preschool. China / epidemiology. Female. Humans. Incidence. Infant. Male. Middle Aged. Palatal Neoplasms / pathology. Parotid Neoplasms / pathology. Retrospective Studies

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  • [ErratumIn] Oral Oncol. 2011 Sep;47(9):929-30
  • (PMID = 17418612.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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14. Foschini MP, Gaiba A, Cocchi R, Pennesi MG, Pession A: p63 expression in salivary gland tumors: role of DeltaNp73L in neoplastic transformation. Int J Surg Pathol; 2005 Oct;13(4):329-35
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  • [Title] p63 expression in salivary gland tumors: role of DeltaNp73L in neoplastic transformation.
  • To illustrate the role of p63 and its truncated variants in salivary gland tumors, 23 consecutive tumors and 6 normal salivary glands were studied immunohistochemically with anti-p63 antibody and by reverse transcriptase (RT) and nested polymerase chain reaction (PCR) to detect p63 isoform expression.
  • Normal salivary glands: p63 antibody-stained basal and myoepithelial cells; by RT and nested PCR, the 2 main isoforms were present, whereas DeltaNp73L was absent.
  • The DeltaNp73L isoform was present in tumoral tissue but absent in normal salivary gland.
  • These data suggest that p63, particularly its splice variant DeltaNp73L, is involved in the neoplastic transformation of salivary glands.
  • [MeSH-major] Cell Transformation, Neoplastic. Phosphoproteins / genetics. Phosphoproteins / metabolism. Salivary Gland Neoplasms / metabolism. Salivary Gland Neoplasms / pathology. Trans-Activators / genetics. Trans-Activators / metabolism
  • [MeSH-minor] Adenocarcinoma / metabolism. Adenocarcinoma / pathology. Adenolymphoma / metabolism. Adenolymphoma / pathology. Adenoma, Oxyphilic / metabolism. Adenoma, Oxyphilic / pathology. Adenoma, Pleomorphic / metabolism. Adenoma, Pleomorphic / pathology. Adult. Aged. Carcinoma, Adenoid Cystic / metabolism. Carcinoma, Adenoid Cystic / pathology. Cell Proliferation. DNA-Binding Proteins. Exons. Female. Gene Expression Regulation, Neoplastic. Genes, Tumor Suppressor. Humans. Immunohistochemistry. Male. Middle Aged. Myoepithelioma / metabolism. Myoepithelioma / pathology. Polymerase Chain Reaction. Protein Isoforms. Reverse Transcriptase Polymerase Chain Reaction. Salivary Glands / cytology. Salivary Glands / metabolism. Salivary Glands / pathology. Transcription Factors. Tumor Suppressor Proteins

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  • (PMID = 16273188.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA-Binding Proteins; 0 / Phosphoproteins; 0 / Protein Isoforms; 0 / TP63 protein, human; 0 / Trans-Activators; 0 / Transcription Factors; 0 / Tumor Suppressor Proteins
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15. Bień S, Kamiński B, Kopczyński J, Sygut J: [The synchroneous tumors of different histopathology in the parotid salivary gland]. Otolaryngol Pol; 2006;60(5):703-8

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  • [Title] [The synchroneous tumors of different histopathology in the parotid salivary gland].
  • Ipsilateral salivary gland tumors of different histological types are very rare.
  • In 5 cases pleomorphic adenoma was one of synchronous tumor--in 2 cases with adenocarcinoma and in single cases with salivary duct carcinoma, adenolymphoma, and myoepithelioma.
  • In one case, the adenolymphoma was synchronous with carcinoma planoepitheliale metastaticum from the primary in the skin post auricular area (late metastasis).
  • Following the review of literature concerning the problem, two concepts has been critically discussed--the real synchronous occurrence of two different tumors, and transformation of benign tumor of salivary neoplasm to its malignant form.
  • [MeSH-minor] Adenolymphoma / pathology. Adenoma, Pleomorphic / pathology. Adult. Carcinoma, Squamous Cell / pathology. Female. Humans. Male. Middle Aged. Neoplasm Metastasis

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  • (PMID = 17263242.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Poland
  • [Number-of-references] 24
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16. Driemel O, Kraft K, Hemmer J: [DNA ploidy and proliferative activity in salivary gland tumours]. Mund Kiefer Gesichtschir; 2007 Aug;11(3):139-44
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  • [Title] [DNA ploidy and proliferative activity in salivary gland tumours].
  • DNA ploidy and S-Phase fraction (SPF) of 279 salivary gland tumours were analysed using high-resolution DNA flow cytometry.
  • While aneuploidy represents a distinct indicator of malignancy SPF values are of minor relevance for dignity assessment in salivary gland tumours.
  • [MeSH-major] Cell Division / genetics. DNA, Neoplasm / genetics. Ploidies. Salivary Gland Neoplasms / genetics
  • [MeSH-minor] Adenolymphoma / genetics. Adenolymphoma / pathology. Adenoma, Pleomorphic / genetics. Adenoma, Pleomorphic / pathology. Adolescent. Adult. Aged. Aged, 80 and over. Child. Diagnosis, Differential. Diploidy. Female. Flow Cytometry. Humans. Male. Middle Aged. Salivary Gland Diseases / genetics. Salivary Gland Diseases / pathology. Salivary Glands / pathology. Sensitivity and Specificity

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  • (PMID = 17505845.001).
  • [ISSN] 1432-9417
  • [Journal-full-title] Mund-, Kiefer- und Gesichtschirurgie : MKG
  • [ISO-abbreviation] Mund Kiefer Gesichtschir
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / DNA, Neoplasm
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17. Giefing M, Wierzbicka M, Rydzanicz M, Cegla R, Kujawski M, Szyfter K: Chromosomal gains and losses indicate oncogene and tumor suppressor gene candidates in salivary gland tumors. Neoplasma; 2008;55(1):55-60
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  • [Title] Chromosomal gains and losses indicate oncogene and tumor suppressor gene candidates in salivary gland tumors.
  • The incidence of salivary gland tumor in Poland is growing in the last two decades.
  • 29 salivary tumor samples: Cystadenolymphoma-warthin (15) and adenoma polymorphum (14) located in the parotid (27) and submandibular gland (2) were collected and CGH was performed.
  • Altogether, salivary gland tumors presented a different aberration pattern than these reported for head and neck squamous cell carcinoma (HNSCC) but no significant differences were observed between Warthin and adenoma polymorphum tumors.
  • We show a frequent deletion of the harakiri gene (12q24.2) in 12/29 tumors and TP53 gene (17p13.1) in 11/29 tumors as potential tumor suppressors in salivary gland cancers.
  • The observed alterations may indicate important genetic events in the formation of salivary gland tumors.
  • [MeSH-major] Adenolymphoma / genetics. Adenoma, Pleomorphic / genetics. Chromosome Aberrations. Genes, Tumor Suppressor. Oncogenes. Salivary Gland Neoplasms / genetics

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  • (PMID = 18190242.001).
  • [ISSN] 0028-2685
  • [Journal-full-title] Neoplasma
  • [ISO-abbreviation] Neoplasma
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] Slovakia
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18. Hisatomi M, Asaumi J, Yanagi Y, Unetsubo T, Maki Y, Murakami J, Matsuzaki H, Honda Y, Konouchi H: Diagnostic value of dynamic contrast-enhanced MRI in the salivary gland tumors. Oral Oncol; 2007 Oct;43(9):940-7
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  • [Title] Diagnostic value of dynamic contrast-enhanced MRI in the salivary gland tumors.
  • To evaluate the diagnostic value of dynamic contrast-enhanced MRI (DCE-MRI) in salivary gland tumors, thirty-five patients (47 lesions) who underwent MR examinations and were histopathologically diagnosed with salivary gland tumors in Okayama University Hospital, between April 1998 and March 2005, were entered in the present study.
  • (a) The salivary gland tumors were categorized into three CI curve types according to Tmax and WR300; Pleomorphic adenoma; Tmax > 210 s and WR300 < 10%, Warthin tumor; Tmax < 60 s and WR300 > 40%, and malignant tumor; 60s < Tmax < 210 s and 10% < WR300 < 30%;.
  • Thus, DCE-MRI parameters are useful in diagnosing salivary gland tumors on the basis of the combined assessment of Tmax and CImax or WR.
  • [MeSH-major] Gadolinium DTPA. Image Processing, Computer-Assisted. Magnetic Resonance Imaging / methods. Radiopharmaceuticals. Salivary Gland Neoplasms / diagnosis
  • [MeSH-minor] Adenolymphoma / diagnosis. Adenoma, Pleomorphic / diagnosis. Adult. Aged. Aged, 80 and over. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Parotid Neoplasms / diagnosis. Sensitivity and Specificity

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  • (PMID = 17257881.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; K2I13DR72L / Gadolinium DTPA
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19. Gürbüz Y, Yildiz K, Aydin O, Almaç A: Immunophenotypical profiles of salivary gland tumours: a new evidence for their histogenetic origin. Pathologica; 2006 Apr;98(2):147-52
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  • [Title] Immunophenotypical profiles of salivary gland tumours: a new evidence for their histogenetic origin.
  • The histogenetic origin of salivary gland tumours is not clear.
  • In this study, we examine the immunophenotypic properties of salivary gland tumours in order to obtain further insight into their histogenesis.
  • 30 cases of salivary gland tumours (18 pleomorphic adenomas, 8 Warthin's tumours, 2 basal cell adenomas, 2 acinic cell carcinomas) were included in our study.
  • [MeSH-major] Actins / analysis. Keratins / analysis. Neoplasm Proteins / analysis. Salivary Gland Neoplasms / pathology
  • [MeSH-minor] Adenolymphoma / chemistry. Adenolymphoma / pathology. Adenoma / chemistry. Adenoma / pathology. Adenoma, Pleomorphic / chemistry. Adenoma, Pleomorphic / pathology. Carcinoma, Acinar Cell / chemistry. Carcinoma, Acinar Cell / pathology. Humans. Immunophenotyping. Organ Specificity. Protein Isoforms / analysis. Retrospective Studies

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  • (PMID = 16929788.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Actins; 0 / Neoplasm Proteins; 0 / Protein Isoforms; 68238-35-7 / Keratins
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20. Christiansen H, Wolff HA, Knauth J, Hille A, Vorwerk H, Engelke C, Rödel R, Laskawi R: [Radiotherapy : an option for refractory salivary fistulas]. HNO; 2009 Dec;57(12):1325-8
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  • [Title] [Radiotherapy : an option for refractory salivary fistulas].
  • A 45-year-old patient presented with refractory salivary fistula, attributed to multiple surgery and Botulinum toxin, following lateral parotidectomy.
  • He underwent fractionated radiotherapy of the remaining parotid gland including the fistula opening (total dose of 30 Gy) at our clinic.
  • [MeSH-major] Adenolymphoma / surgery. Botulinum Toxins, Type A / administration & dosage. Cutaneous Fistula / radiotherapy. Parotid Diseases / radiotherapy. Parotid Gland / surgery. Parotid Neoplasms / surgery. Postoperative Complications / radiotherapy. Salivary Gland Fistula / radiotherapy

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  • [Cites] J Oral Maxillofac Surg. 1996 Oct;54(10):1176-9 [8859235.001]
  • [Cites] Eur Arch Otorhinolaryngol. 2008 Feb;265(2):243-5 [17704932.001]
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  • (PMID = 19727624.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] EC 3.4.24.69 / Botulinum Toxins, Type A
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21. Ito FA, Ito K, Vargas PA, de Almeida OP, Lopes MA: Salivary gland tumors in a Brazilian population: a retrospective study of 496 cases. Int J Oral Maxillofac Surg; 2005 Jul;34(5):533-6
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  • [Title] Salivary gland tumors in a Brazilian population: a retrospective study of 496 cases.
  • Salivary gland tumors are uncommon and the microscopical features can be complex.
  • In this study, 496 epithelial and mesenchymal tumors of major and minor salivary glands diagnosed at Londrina Cancer Institute during the period from 1972 to 2001 were reviewed.
  • The majority of the cases occurred in the parotid gland (67.7%), followed by the minor salivary glands (22.8%) and submandibular gland (9.5%).
  • Among the minor salivary gland tumors, the palate was the most frequent location (67%).
  • [MeSH-major] Salivary Gland Neoplasms / epidemiology
  • [MeSH-minor] Adenolymphoma / epidemiology. Adenoma, Pleomorphic / epidemiology. Adolescent. Adult. Age Factors. Aged. Aged, 80 and over. Brazil / epidemiology. Carcinoma, Adenoid Cystic / epidemiology. Carcinoma, Mucoepidermoid / epidemiology. Child. Female. Humans. Male. Middle Aged. Neoplasms, Glandular and Epithelial / epidemiology. Palate / pathology. Parotid Neoplasms / epidemiology. Retrospective Studies. Salivary Glands, Minor / pathology. Sex Factors. Submandibular Gland Neoplasms / epidemiology

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  • (PMID = 16053874.001).
  • [ISSN] 0901-5027
  • [Journal-full-title] International journal of oral and maxillofacial surgery
  • [ISO-abbreviation] Int J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
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22. Dalpa E, Gourvas V, Baritaki S, Miyakis S, Samaras V, Barbatis C, Sourvinos G, Spandidos DA: High prevalence of Human Herpes Virus 8 (HHV-8) in patients with Warthin's tumors of the salivary gland. J Clin Virol; 2008 Jun;42(2):182-5
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  • [Title] High prevalence of Human Herpes Virus 8 (HHV-8) in patients with Warthin's tumors of the salivary gland.
  • BACKGROUND: Warthin's tumor is a common benign neoplasm of the salivary gland.
  • Human Herpes Virus 8 (HHV-8) is the etiologic agent for all forms of Kaposi's sarcoma (KS), and HHV-8 DNA is present in saliva, suggesting that non-sexual transmission is associated with latent infection of the salivary gland.
  • OBJECTIVES: To provide insights into the HHV-8 cell tropism, the presence of HHV-8 was investigated in a series of Warthin's tumors of the salivary gland and corresponding adjacent normal tissue.
  • RESULTS: HHV-8 DNA was detected in 19 out of 43 (44%) salivary gland tumor samples.
  • CONCLUSIONS: HHV-8 is frequently detected in adenoid salivary neoplasms, suggesting a significant role of the virus in the etiopathogenesis of the disease.
  • [MeSH-major] Adenolymphoma / virology. Herpesvirus 8, Human / isolation & purification. Salivary Gland Neoplasms / virology. Salivary Glands / virology

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  • (PMID = 18339579.001).
  • [ISSN] 1386-6532
  • [Journal-full-title] Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
  • [ISO-abbreviation] J. Clin. Virol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / DNA, Viral
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23. Honjo N, Gunduz M, Fukushima K, Cengiz B, Beder LB, Gunduz E, Nagatsuka H, Xiao J, Shimizu K, Nishizaki K: Comprehensive loss of heterozygosity analysis and identification of a novel hotspot at 3p21 in salivary gland neoplasms. Otolaryngol Head Neck Surg; 2007 Jul;137(1):119-25

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  • [Title] Comprehensive loss of heterozygosity analysis and identification of a novel hotspot at 3p21 in salivary gland neoplasms.
  • OBJECTIVES: We sought to assess loss of heterozygosity (LOH) profiles of 3p, 6q, 8q, 10q, 12q, 13q, and 17p and to identify the tumor suppressor genes involved in salivary gland neoplasms.
  • STUDY DESIGN: LOH analysis was performed using 26 microsatellite markers by polymerase chain reaction-polyacrylamide gel electrophoresis method in 20 benign and 6 malignant salivary gland tumors.
  • CONCLUSIONS AND SIGNIFICANCE: The hotspot regions defined by the present study suggest that new tumor suppressor genes related to the development of salivary gland tumors may reside at several chromosomal loci, including loci at 3p, 6q, 8q and 10q.
  • [MeSH-major] Chromosomes, Human, Pair 3 / genetics. Loss of Heterozygosity / genetics. Parotid Neoplasms / genetics. Submandibular Gland Neoplasms / genetics
  • [MeSH-minor] Adenolymphoma / genetics. Adenoma, Pleomorphic / genetics. Adult. Aged. Carcinoma / genetics. Carcinoma, Squamous Cell / genetics. Chromosome Mapping. Chromosomes, Human, Pair 10 / genetics. Chromosomes, Human, Pair 12 / genetics. Chromosomes, Human, Pair 13 / genetics. Chromosomes, Human, Pair 17 / genetics. Chromosomes, Human, Pair 6 / genetics. Chromosomes, Human, Pair 8 / genetics. Female. Genes, Tumor Suppressor. Humans. Male. Microsatellite Repeats / genetics. Middle Aged

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  • (PMID = 17599578.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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24. Edwards PC, Wasserman P: Evaluation of cystic salivary gland lesions by fine needle aspiration: an analysis of 21 cases. Acta Cytol; 2005 Sep-Oct;49(5):489-94
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  • [Title] Evaluation of cystic salivary gland lesions by fine needle aspiration: an analysis of 21 cases.
  • OBJECTIVE: To analyze the potential sources of diagnostic errors and overall accuracy rate of the fine needle aspiration biopsy (FNAB) diagnosis of cystic salivary gland neoplasms.
  • STUDY DESIGN: A 10-year (1993-2002) retrospective review of the cytopathology slides from the Division of Cytopathology, Department of Pathology, Long Island Jewish Medical Center, New Hyde Park, New York, identified a total of 97 consecutive salivary gland FNAB cases that microscopically were interpreted as representing cystic lesions.
  • RESULTS: A correct diagnosis was rendered by FNAB in 15 of 21 (72%) cases.
  • CONCLUSION: A systematic approach to the diagnosis of cystic salivary gland lesions by FNAB can result in a correct diagnosis in > 70% of cases.
  • It is important to recognize, however, that occasionally epithelial cells may not be detected on FNAB of cystic salivary gland lesions, as a result of either cellular dilution by cystfluid or inadequate sampling.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Diagnostic Errors / prevention & control. Epithelial Cells / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands / pathology
  • [MeSH-minor] Abscess / pathology. Adenolymphoma / pathology. Biopsy, Fine-Needle. Carcinoma, Mucoepidermoid / pathology. Cystadenoma / pathology. Diagnosis, Differential. Extracellular Fluid / metabolism. Histiocytes / pathology. Humans. Lymphocytes / pathology. Observer Variation. Predictive Value of Tests. Reproducibility of Results. Retrospective Studies

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  • [CommentIn] Acta Cytol. 2007 Jul-Aug;51(4):675-6 [17718154.001]
  • (PMID = 16334024.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
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25. Varshavskiĭ AI: [Clinics, diagnostics and treatment of parotid salivary gland adenomas]. Stomatologiia (Mosk); 2010;89(3):41-4
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  • [Title] [Clinics, diagnostics and treatment of parotid salivary gland adenomas].
  • Clinical data of 252 patients with parotid gland adenomas (PGA) were produced.
  • Pleomorphic adenoma (PA) was found in 81.3% of PGA cases, adenolymphoma (Warthin's tumor) - in 13%, canalicular adenoma - in 2.8%, other adenomas - in 2.9% of observations.
  • PA more often was met in women, adenolymphoma - in men.
  • 2 cases of myoepithelioma and cystadenoma of parotid gland were described.
  • The following operations were performed: extracapsular tumorectomy - in 13 patients, adenomectomy with limited gland resection - in 152 patients, subtotal gland resection with nervus facialis separation - in 62 patients, parotidectomy with nervus facialis preservation - in 25 patients.
  • [MeSH-major] Adenoma / diagnosis. Adenoma / surgery. Parotid Neoplasms / diagnosis. Parotid Neoplasms / surgery

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  • (PMID = 20559235.001).
  • [ISSN] 0039-1735
  • [Journal-full-title] Stomatologii︠a︡
  • [ISO-abbreviation] Stomatologiia (Mosk)
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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26. Chang KT, Chadha NK, Leung R, Shago M, Phillips MJ, Thorner PS: Lymphadenoma: case report of a rare salivary gland tumor in childhood. Pediatr Dev Pathol; 2010 Jul-Aug;13(4):331-7
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  • [Title] Lymphadenoma: case report of a rare salivary gland tumor in childhood.
  • Lymphadenoma of the salivary gland is a rare benign tumor with only 11 reported cases in the English language literature, most of which have occurred in adults.
  • We report a case of a lymphadenoma occurring in the parotid gland of a 15-year-old girl.
  • [MeSH-major] Adenolymphoma / pathology. Parotid Neoplasms / pathology
  • [MeSH-minor] Adolescent. Biomarkers, Tumor / metabolism. Carcinoma, Mucoepidermoid / diagnosis. Carcinoma, Mucoepidermoid / secondary. Cytoplasmic Structures / ultrastructure. Diagnosis, Differential. Female. Humans. Keratins / metabolism. Lymphocytes / ultrastructure. Plasma Cells / ultrastructure. Proto-Oncogene Proteins c-kit / metabolism. Trans-Activators / metabolism. Transcription Factors. Treatment Outcome. Tumor Suppressor Proteins / metabolism

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  • (PMID = 20021220.001).
  • [ISSN] 1093-5266
  • [Journal-full-title] Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
  • [ISO-abbreviation] Pediatr. Dev. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / TP63 protein, human; 0 / Trans-Activators; 0 / Transcription Factors; 0 / Tumor Suppressor Proteins; 68238-35-7 / Keratins; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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27. Maruya S, Kies MS, Williams M, Myers JN, Weber RS, Batsakis JG, El-Naggar AK: Differential expression of p63 isotypes (DeltaN and TA) in salivary gland neoplasms: biological and diagnostic implications. Hum Pathol; 2005 Jul;36(7):821-7
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  • [Title] Differential expression of p63 isotypes (DeltaN and TA) in salivary gland neoplasms: biological and diagnostic implications.
  • To determine the association between the expression of p63 gene isoforms (TA and DeltaN) and salivary gland tumorigenesis, we performed reverse transcription-polymerase chain reaction analysis of these markers in 71 benign and malignant salivary gland neoplasms.
  • Both p63 isoforms were either negative or weakly expressed in normal salivary gland tissues.
  • We conclude that (1) p63 isoforms are differentially expressed in most benign and malignant tumors and may play distinct biological roles in certain salivary gland neoplasms;.
  • [MeSH-major] Adenocarcinoma / metabolism. Adenolymphoma / metabolism. Adenoma, Pleomorphic / metabolism. Genes, Tumor Suppressor. Phosphoproteins / metabolism. Salivary Gland Neoplasms / metabolism. Trans-Activators / metabolism
  • [MeSH-minor] Calcium-Binding Proteins. DNA Primers / chemistry. DNA-Binding Proteins. Gene Expression Regulation, Neoplastic. Humans. Immunoenzyme Techniques. Intercellular Signaling Peptides and Proteins. Membrane Proteins / genetics. Membrane Proteins / metabolism. Protein Isoforms. RNA, Messenger / metabolism. RNA, Neoplasm / genetics. Reverse Transcriptase Polymerase Chain Reaction. Salivary Glands / metabolism. Salivary Glands / pathology. Transcription Factors. Tumor Suppressor Proteins

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  • (PMID = 16084953.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Calcium-Binding Proteins; 0 / DNA Primers; 0 / DNA-Binding Proteins; 0 / Intercellular Signaling Peptides and Proteins; 0 / Membrane Proteins; 0 / Phosphoproteins; 0 / Protein Isoforms; 0 / RNA, Messenger; 0 / RNA, Neoplasm; 0 / TP63 protein, human; 0 / Trans-Activators; 0 / Transcription Factors; 0 / Tumor Suppressor Proteins; 134324-36-0 / Serrate proteins
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28. Shigeishi H, Yoneda S, Taki M, Nobumori T, Ohta K, Higashikawa K, Yasui W, Kamata N: Correlation of human Bub1 expression with tumor-proliferating activity in salivary gland tumors. Oncol Rep; 2006 Apr;15(4):933-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Correlation of human Bub1 expression with tumor-proliferating activity in salivary gland tumors.
  • We examined the expression of Bub1 mRNA and protein in 21 human salivary gland tumors (7 pleomorphic adenomas, 2 warthin tumors, 5 mucoepidermoid carcinomas, 3 adenoid cystic carcinomas and 4 acinic cell carcinomas) and 3 normal submandibular glands using real-time quantitative reverse transcription-polymerase chain reaction (RT-PCR) or western blotting.
  • A significant correlation was found between Bub1 mRNA/protein expression and the Ki-67 labeling index in salivary gland tumors (Spearman's correlation coefficient by rank test, p=0.026/p=0.002).
  • [MeSH-major] Cell Proliferation. Protein Kinases / genetics. Salivary Gland Neoplasms / pathology
  • [MeSH-minor] Adenolymphoma / genetics. Adenolymphoma / metabolism. Adenolymphoma / pathology. Adenoma, Pleomorphic / genetics. Adenoma, Pleomorphic / metabolism. Adenoma, Pleomorphic / pathology. Blotting, Western. Carcinoma, Acinar Cell / genetics. Carcinoma, Acinar Cell / metabolism. Carcinoma, Acinar Cell / pathology. Carcinoma, Adenoid Cystic / genetics. Carcinoma, Adenoid Cystic / metabolism. Carcinoma, Adenoid Cystic / pathology. Carcinoma, Mucoepidermoid / genetics. Carcinoma, Mucoepidermoid / metabolism. Carcinoma, Mucoepidermoid / pathology. Gene Expression Regulation, Neoplastic. Humans. Immunohistochemistry. Ki-67 Antigen / analysis. Neoplasm Staging. Proliferating Cell Nuclear Antigen / analysis. Protein-Serine-Threonine Kinases. RNA, Messenger / genetics. RNA, Messenger / metabolism. Reverse Transcriptase Polymerase Chain Reaction

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  • (PMID = 16525682.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Ki-67 Antigen; 0 / Proliferating Cell Nuclear Antigen; 0 / RNA, Messenger; EC 2.7.- / Protein Kinases; EC 2.7.11.1 / BUB1 protein, human; EC 2.7.11.1 / Bub1 spindle checkpoint protein; EC 2.7.11.1 / Protein-Serine-Threonine Kinases
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29. Brennan PA, Davies B, Poller D, Mead Z, Bayne D, Puxeddu R, Oeppen RS: Fine needle aspiration cytology (FNAC) of salivary gland tumours: repeat aspiration provides further information in cases with an unclear initial cytological diagnosis. Br J Oral Maxillofac Surg; 2010 Jan;48(1):26-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fine needle aspiration cytology (FNAC) of salivary gland tumours: repeat aspiration provides further information in cases with an unclear initial cytological diagnosis.
  • INTRODUCTION: Fine needle aspiration cytology (FNAC) for salivary gland tumours requires expertise in interpretation.
  • When a diagnosis is not clear (despite a cellular aspirate), published work is lacking on the value of repeating the test.
  • METHODS: A retrospective study of 135 patients who had FNAC followed by definitive excision for a suspected salivary gland tumour.
  • A definite cytological diagnosis was subsequently made in 27/33 patients (82%).
  • CONCLUSIONS: Repeat FNAC may provide a cytological diagnosis in cases where the initial diagnosis is not clear, although cytology should be used in conjunction with other investigations of salivary tumours, including image-guided biopsy examination where appropriate.
  • Ideally salivary gland FNAC should be interpreted by a specialist pathologist.
  • [MeSH-major] Biopsy, Fine-Needle / methods. Salivary Gland Neoplasms / pathology
  • [MeSH-minor] Adenolymphoma / pathology. Adenoma / pathology. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / secondary. Cytodiagnosis. Diagnosis, Differential. Humans. Lymphoma / pathology. Parotid Neoplasms / pathology. Predictive Value of Tests. Retrospective Studies. Sensitivity and Specificity. Submandibular Gland Neoplasms / pathology. Ultrasonography, Interventional

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  • [Copyright] Copyright 2009 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 19233526.001).
  • [ISSN] 1532-1940
  • [Journal-full-title] The British journal of oral & maxillofacial surgery
  • [ISO-abbreviation] Br J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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30. Tian Z, Li L, Wang L, Hu Y, Li J: Salivary gland neoplasms in oral and maxillofacial regions: a 23-year retrospective study of 6982 cases in an eastern Chinese population. Int J Oral Maxillofac Surg; 2010 Mar;39(3):235-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Salivary gland neoplasms in oral and maxillofacial regions: a 23-year retrospective study of 6982 cases in an eastern Chinese population.
  • There is little information in the English-language literature about the epidemiology of salivary gland neoplasms in the eastern Chinese population.
  • A large retrospective study (6982 primary salivary tumors during 23 years) was carried out to investigate the clinicopathological features (tumor location, patient sex and age) of these tumors in this population.
  • The salivary tumors slightly predominated in males.
  • Relatively higher incidences of minor gland tumors and specifically of pleomorphic adenoma in minor glands were noted.
  • [MeSH-major] Salivary Gland Neoplasms / epidemiology
  • [MeSH-minor] Adenocarcinoma / epidemiology. Adenolymphoma / epidemiology. Adenoma, Pleomorphic / epidemiology. Adolescent. Adult. Age Factors. Aged. Aged, 80 and over. Carcinoma / epidemiology. Carcinoma, Adenoid Cystic / epidemiology. Carcinoma, Mucoepidermoid / epidemiology. Child. China / epidemiology. Female. Humans. Incidence. Male. Middle Aged. Palatal Neoplasms / epidemiology. Parotid Neoplasms / epidemiology. Retrospective Studies. Salivary Glands, Minor / pathology. Sex Factors. Submandibular Gland Neoplasms / epidemiology. Young Adult

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  • (PMID = 19951834.001).
  • [ISSN] 1399-0020
  • [Journal-full-title] International journal of oral and maxillofacial surgery
  • [ISO-abbreviation] Int J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
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31. Guldfred LA, Becker BC, Eiholm S: [Multiple synchronous tumours of different histological type of the salivary glands]. Ugeskr Laeger; 2008 Apr 28;170(18):1571

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Multiple synchronous tumours of different histological type of the salivary glands].
  • Multiple tumours of different histological type of the salivary glands are extremely rare.
  • Here we report a 72-year-old woman who was diagnosed with simultaneously occurring Warthin's tumour of the left parotid and mixed tumour of the homolateral submandibular gland.
  • [MeSH-major] Adenolymphoma / pathology. Adenoma, Pleomorphic / pathology. Neoplasms, Multiple Primary / pathology. Parotid Neoplasms / pathology. Submandibular Gland Neoplasms / pathology

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  • (PMID = 18454930.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Denmark
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32. Tanaka S, Tabuchi K, Oikawa K, Kohanawa R, Okubo H, Ikebe D, Noguchi M, Hara A: Synchronous unilateral parotid gland neoplasms of three different histological types. Auris Nasus Larynx; 2007 Jun;34(2):263-6

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  • [Title] Synchronous unilateral parotid gland neoplasms of three different histological types.
  • A 67-year-old male with three synchronous tumors in the unilateral parotid gland is reported.
  • Postoperative histological examinations confirmed the presence of three synchronous primary tumors, specifically pleomorphic adenoma, Warthin's tumor and salivary duct carcinoma, in the right parotid gland.
  • To our knowledge, this is the first case report describing three different histological types in the unilateral parotid gland.
  • [MeSH-major] Adenolymphoma / pathology. Adenoma, Pleomorphic / pathology. Carcinoma / pathology. Neoplasms, Multiple Primary / pathology. Parotid Neoplasms / pathology. Salivary Ducts / pathology
  • [MeSH-minor] Aged. Humans. Male. Parotid Gland / pathology

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  • (PMID = 16938417.001).
  • [ISSN] 0385-8146
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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33. Majeed M, Murray B, Hume W, Makura Z: Sebaceous lymphadenoma of the parotid gland. Dentomaxillofac Radiol; 2008 Jul;37(5):300-4
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  • [Title] Sebaceous lymphadenoma of the parotid gland.
  • Sebaceous differentiation in salivary gland tissue is common.
  • However, sebaceous neoplasms within the salivary glands are rare.
  • We present the case of a sebaceous lymphadenoma with unusual features, arising in the parotid gland of a 60-year-old male.
  • The difficulties encountered in reaching a definitive diagnosis both radiologically and histologically are described.
  • [MeSH-major] Adenolymphoma / diagnosis. Parotid Neoplasms / diagnosis. Sebaceous Gland Neoplasms / diagnosis

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  • (PMID = 18606753.001).
  • [ISSN] 0250-832X
  • [Journal-full-title] Dento maxillo facial radiology
  • [ISO-abbreviation] Dentomaxillofac Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Contrast Media; K2I13DR72L / Gadolinium DTPA
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34. Tilakaratne WM, Jayasooriya PR, Tennakoon TM, Saku T: Epithelial salivary tumors in Sri Lanka: a retrospective study of 713 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2009 Jul;108(1):90-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epithelial salivary tumors in Sri Lanka: a retrospective study of 713 cases.
  • OBJECTIVE: The aim of this retrospective study was to evaluate the clinicopathologic data to determine the distribution of epithelial salivary tumors, especially minor salivary tumors, in Sri Lanka.
  • MATERIALS AND METHODS: A total of 713 salivary tumors diagnosed at the Department of Oral Pathology, during the period from 1990 to 2007 were reviewed.
  • RESULTS: Out of the 713 epithelial salivary tumors, 356 (49.9%) were classified as benign and 357 (50.1%) as malignant, indicating a benign-to-malignant ratio of 1:1.
  • The majority of both benign (29%) and malignant (39%) tumors occurred in the minor salivary glands.
  • Malignant tumors were slightly more common in minor salivary glands, indicating a benign-to-malignant ratio of 1:0.75.
  • Among the minor salivary sites, palate was the most frequent location, accounting for 51% of the tumors (246 out of 486).
  • The commonest benign and malignant tumors were pleomorphic adenoma and mucoepidermoid carcinoma in both major and minor salivary glands.
  • CONCLUSION: According to the findings of this study, equal frequencies of benign and malignant tumors indicate higher occurrences of malignancies, especially in the minor salivary glands, in the Sri Lankan population.
  • [MeSH-major] Neoplasms, Glandular and Epithelial / epidemiology. Salivary Gland Neoplasms / epidemiology
  • [MeSH-minor] Adenolymphoma / epidemiology. Adenoma, Pleomorphic / epidemiology. Adult. Age Factors. Aged. Aged, 80 and over. Carcinoma / epidemiology. Carcinoma, Adenoid Cystic / epidemiology. Carcinoma, Mucoepidermoid / epidemiology. Female. Humans. Male. Middle Aged. Palatal Neoplasms / epidemiology. Parotid Neoplasms / epidemiology. Retrospective Studies. Salivary Glands, Minor / pathology. Sex Factors. Sri Lanka / epidemiology

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  • (PMID = 19403317.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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35. Ihrler S, Adam P, Guntinas-Lichius O, Harrison JD, Weiler C: [Pattern recognition in the differential diagnosis of salivary lymphoepithelial lesions]. Pathologe; 2009 Nov;30(6):432-41
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pattern recognition in the differential diagnosis of salivary lymphoepithelial lesions].
  • The prototype of a salivary lymphoepithelial lesion is the autoimmune disease Sjögren's syndrome with the characteristic lymphoepithelial duct lesions (LEL).
  • The distinction of Sjögren's syndrome from cases with initial transformation into associated marginal zone B-cell lymphoma (MALT type) can be very challenging, whereby the presence of small "halos" can lead to over-diagnosis.
  • The sporadic lymphoepithelial cyst of the parotid gland is a frequent finding and has no clinical consequence; however, this entity needs to be identified and distinguished from the above-mentioned entities.
  • The most frequent diagnosis in resected submandibular glands is chronic-fibrosing sialadenitis, so-called Küttner's tumour.
  • Altogether, there is a wide spectrum of lymphoepithelial interaction in the area of salivary glands, including biphasic lymphoepithelial tumours with an obligate lymphoid component, epithelial tumours with facultative tumour-associated lymphoid proliferation, and different processes of intraparotid lymph nodes.
  • The relative frequency of the lesions in different salivary glands can also be diagnostically helpful.
  • [MeSH-major] Cell Transformation, Neoplastic / pathology. Lymphoma, B-Cell, Marginal Zone / diagnosis. Lymphoma, B-Cell, Marginal Zone / pathology. Salivary Gland Neoplasms / diagnosis. Salivary Gland Neoplasms / pathology. Sjogren's Syndrome / diagnosis. Sjogren's Syndrome / pathology
  • [MeSH-minor] Adenolymphoma / diagnosis. Adenolymphoma / pathology. Chronic Disease. Cysts / diagnosis. Cysts / pathology. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Neoplasm Staging. Parotid Gland. Parotid Neoplasms / diagnosis. Parotid Neoplasms / pathology. Parotitis / diagnosis. Parotitis / pathology. Recurrence. Salivary Glands / pathology. Sensitivity and Specificity. Sialadenitis / diagnosis. Sialadenitis / pathology. Submandibular Gland / pathology. Tomography, X-Ray Computed

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  • (PMID = 19813014.001).
  • [ISSN] 1432-1963
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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36. Dumitriu D, Dudea SM, Botar-Jid C, Băciuţ G: Ultrasonographic and sonoelastographic features of pleomorphic adenomas of the salivary glands. Med Ultrason; 2010 Sep;12(3):175-83
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ultrasonographic and sonoelastographic features of pleomorphic adenomas of the salivary glands.
  • PATIENTS AND METHODS: Between April 2007 and February 2010, 70 salivary gland masses were examined prospectively (58 in the parotid gland, 12 in the submandibular gland).
  • [MeSH-major] Adenolymphoma / ultrasonography. Adenoma, Pleomorphic / ultrasonography. Elasticity Imaging Techniques / methods. Salivary Gland Neoplasms / ultrasonography

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  • (PMID = 21203593.001).
  • [ISSN] 1844-4172
  • [Journal-full-title] Medical ultrasonography
  • [ISO-abbreviation] Med Ultrason
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Romania
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37. Demasi AP, Furuse C, Altemani A, Junqueira JL, Oliveira PR, Araújo VC: Peroxiredoxin I is overexpressed in oncocytic lesions of salivary glands. J Oral Pathol Med; 2009 Jul;38(6):514-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Peroxiredoxin I is overexpressed in oncocytic lesions of salivary glands.
  • BACKGROUND: Oncocytic lesions, particularly frequent in the salivary glands, are characterized by cells with an atypical accumulation of mitochondria.
  • METHODS: In this study, we evaluated Prx I expression in oncocytic lesions of salivary glands by immunohistochemistry.
  • RESULTS: Our results showed that Prx I is overexpressed in oncocytes regardless of the salivary gland lesion where they appear.
  • [MeSH-major] Oxyphil Cells / enzymology. Peroxiredoxins / analysis. Salivary Glands / enzymology
  • [MeSH-minor] Adenocarcinoma / enzymology. Adenocarcinoma / pathology. Adenolymphoma / enzymology. Adenolymphoma / pathology. Adenoma, Oxyphilic / enzymology. Adenoma, Oxyphilic / pathology. Antioxidants / analysis. Biomarkers / analysis. Carcinoma, Mucoepidermoid / enzymology. Carcinoma, Mucoepidermoid / pathology. Free Radical Scavengers / analysis. Gene Expression Regulation, Enzymologic. Granular Cell Tumor / enzymology. Granular Cell Tumor / pathology. Humans. Hydrogen Peroxide / analysis. Hyperplasia. Lysosomes / pathology. Metaplasia. Mitochondria / pathology. Reactive Oxygen Species / analysis. Salivary Gland Neoplasms / enzymology. Salivary Gland Neoplasms / pathology. Thyroid Gland / pathology

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  • (PMID = 19298244.001).
  • [ISSN] 1600-0714
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antioxidants; 0 / Biomarkers; 0 / Free Radical Scavengers; 0 / Reactive Oxygen Species; BBX060AN9V / Hydrogen Peroxide; EC 1.11.1.15 / Peroxiredoxins
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38. Roh JL, Kim JM, Park CI: Synchronous benign and malignant tumors in the ipsilateral parotid gland. Acta Otolaryngol; 2007 Jan;127(1):110-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Synchronous benign and malignant tumors in the ipsilateral parotid gland.
  • Synchronous benign and malignant tumors in the ipsilateral salivary glands are extremely rare.
  • We describe this case of rare synchronous salivary gland tumors exhibiting both benign and malignant components with a review of the literature.
  • [MeSH-major] Adenocarcinoma / pathology. Adenocarcinoma / radiography. Adenolymphoma / diagnosis. Neoplasms, Multiple Primary / diagnosis. Parotid Neoplasms / diagnosis

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  • (PMID = 17364340.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Norway
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39. Tirado Y, Williams MD, Hanna EY, Kaye FJ, Batsakis JG, El-Naggar AK: CRTC1/MAML2 fusion transcript in high grade mucoepidermoid carcinomas of salivary and thyroid glands and Warthin's tumors: implications for histogenesis and biologic behavior. Genes Chromosomes Cancer; 2007 Jul;46(7):708-15
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] CRTC1/MAML2 fusion transcript in high grade mucoepidermoid carcinomas of salivary and thyroid glands and Warthin's tumors: implications for histogenesis and biologic behavior.
  • We analyzed 55 primary salivary gland tumors including 22 mucoepidermoid carcinomas (MECs) to determine the association of MECT1/TORC1/CRTC1-MAML2 fusion transcript to tumor types, level of MEC differentiation and clinicopathologic parameters.
  • Our primary salivary gland tumors were composed of 22 MECs, 11 Warthin's tumors, 10 adenoid cystic carcinomas, two basaloid carcinomas, five salivary duct carcinomas, and five adenocarcinomas, not otherwise specified.
  • We also included, for the first time, three primary MECs of the thyroid gland.
  • Eighteen (81%) of the 22 primary salivary and one of the three thyroid glands with MEC were positive for the fusion transcript.
  • None of the 22 primary non-MEC gland salivary carcinomas were positive for the transcript.
  • We conclude that the CRTC1/MAML2 transcript may be detected in both low and high grade MEC, that fusion negative tumors may define a subset of biologically aggressive MEC's tumors, that the fusion is present in primary MECs of the thyroid gland and is also detectable in Warthin's tumor, and that a subset of MECs can be targeted for therapeutic intervention.
  • [MeSH-major] Adenolymphoma / genetics. Carcinoma, Mucoepidermoid / genetics. DNA-Binding Proteins / genetics. Nuclear Proteins / genetics. RNA, Messenger / genetics. Salivary Gland Neoplasms / genetics. Thyroid Neoplasms / genetics. Transcription Factors / genetics

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  • (PMID = 17437281.001).
  • [ISSN] 1045-2257
  • [Journal-full-title] Genes, chromosomes & cancer
  • [ISO-abbreviation] Genes Chromosomes Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CRTC1 protein, human; 0 / DNA Primers; 0 / DNA-Binding Proteins; 0 / MAML2 protein, human; 0 / Nuclear Proteins; 0 / RNA, Messenger; 0 / Recombinant Fusion Proteins; 0 / Transcription Factors
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40. Bell D, Luna MA: Warthin adenocarcinoma: analysis of 2 cases of a distinct salivary neoplasm. Ann Diagn Pathol; 2009 Jun;13(3):201-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Warthin adenocarcinoma: analysis of 2 cases of a distinct salivary neoplasm.
  • The aim of this study is to describe the clinicopathologic features of a distinct salivary gland neoplasm, previously undescribed, with a striated duct phenotype arising from WT.
  • Anderson Cancer Center for cases of malignant WT and salivary adenocarcinoma not otherwise specified diagnosed from January 1, 1985, through December 31, 2006, and evaluated patients' medical records and pathologic material.
  • We identified 2 cases of WA; both patients were women, 44 and 60 years of age, with 4.0- and 4.5-cm tumors in the left parotid gland.
  • Warthin adenocarcinoma is a unique salivary gland carcinoma representing the malignant epithelial counterpart of WT.
  • [MeSH-major] Adenocarcinoma / pathology. Adenolymphoma / pathology. Salivary Gland Neoplasms / pathology

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  • (PMID = 19433301.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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41. Jezewska E, Scinska A, Kukwa W, Bienkowski P: Effects of benign parotid tumors on unstimulated saliva secretion from the parotid gland. Auris Nasus Larynx; 2009 Oct;36(5):586-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effects of benign parotid tumors on unstimulated saliva secretion from the parotid gland.
  • OBJECTIVE: Salivary tumors can manifest as abnormalities of the gland itself and/or changes in salivary flow.
  • However, effects of salivary tumors on saliva secretion have not been studied in much detail.
  • The aim of the present study was to evaluate effects of benign parotid tumors on unstimulated saliva secretion from the affected gland.
  • RESULTS: The range of salivary flow was similar to that found in studies on unstimulated parotid saliva.
  • Salivary flow did not differ between the involved and non-involved side.
  • CONCLUSION: The present results suggest that the most common benign parotid tumors do not alter unstimulated salivary flow from the affected gland.
  • [MeSH-major] Adenolymphoma / secretion. Adenoma, Pleomorphic / secretion. Parotid Gland / secretion. Parotid Neoplasms / secretion. Saliva / secretion

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  • (PMID = 19249167.001).
  • [ISSN] 1879-1476
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
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42. Castelino-Prabhu S, Li QK, Ali SZ: Nonsebaceous lymphadenoma of the parotid gland: cytopathologic findings and differential diagnosis. Diagn Cytopathol; 2010 Feb;38(2):137-40

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nonsebaceous lymphadenoma of the parotid gland: cytopathologic findings and differential diagnosis.
  • Lymphadenomas (sebaceous and nonsebaceous types) of the salivary glands are extremely uncommon benign neoplasms.
  • There are rare published reports of cytopathologic characteristics of "nonsebaceous lymphadenomas" of the parotid gland.
  • The rarity of this neoplasm and its superficial resemblance to more common salivary gland neoplasms may present diagnostic issues on FNA.
  • [MeSH-minor] Adenolymphoma / pathology. Aged, 80 and over. Biopsy, Fine-Needle. Cholecystectomy. Diagnosis, Differential. Female. Humans. Hysterectomy. Pneumonectomy. Tonsillectomy

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  • (PMID = 19670220.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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43. Lü BJ, Zhu J, Gao L, Xie L, Xu JY, Lai MD: [Diagnostic accuracy and pitfalls in fine needle aspiration cytology of salivary glands: a study of 113 cases]. Zhonghua Bing Li Xue Za Zhi; 2005 Nov;34(11):706-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Diagnostic accuracy and pitfalls in fine needle aspiration cytology of salivary glands: a study of 113 cases].
  • OBJECTIVE: To describe the fine needle aspiration cytology (FNAC) features of various salivary gland lesions and to analyze the respective diagnostic value and pitfalls.
  • METHODS: 113 FNAC specimens of salivary gland lesions were reviewed and correlated with clinical and histopathologic findings.
  • CONCLUSIONS: FNAC is reliable in distinguishing benign and malignant salivary gland lesions.
  • A specific cytologic diagnosis is often possible.
  • On the other hand, due to the pitfalls in cytologic diagnosis of certain salivary gland tumors, tissue biopsy for histologic examination may be necessary.
  • [MeSH-major] Carcinoma, Mucoepidermoid / pathology. Carcinoma, Squamous Cell / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands / pathology
  • [MeSH-minor] Adenolymphoma / pathology. Adenoma / pathology. Adenoma, Pleomorphic / pathology. Adolescent. Adult. Aged. Biopsy, Fine-Needle. Carcinoma, Adenoid Cystic / pathology. Child. Diagnosis, Differential. Diagnostic Errors. Female. Humans. Male. Middle Aged. Parotid Neoplasms / pathology. Retrospective Studies. Submandibular Gland Neoplasms / pathology

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  • (PMID = 16536312.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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44. Ozcan C, Apa DD, Vayisoglu Y, Görür K: Unilateral parotid gland involvement with synchronous multiple Basal cell adenomas. J Craniofac Surg; 2007 Nov;18(6):1470-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unilateral parotid gland involvement with synchronous multiple Basal cell adenomas.
  • Basal cell adenoma (BCA) is a rare benign epithelial tumor of the salivary gland.
  • BCA is seen most frequently in the parotid gland and less commonly in the submandibular gland and minor glands of the upper lips, oral cavity, and hard palate.
  • Salivary gland tumors are observed as single tumors in one salivary gland.
  • Double or multiple tumors of the salivary gland tumors are unusual and metachronous or bilateral salivary gland tumors are more observed than synchronous or unilateral tumors.
  • Physical examination revealed two solid and well-delineated masses in the preauricular region, which were 1.5 x 1 cm in diameter and in the tail of the parotid gland, which is 2.5 x 2 cm in diameter.
  • Excision of the superficial lobe of the parotid gland was performed.
  • Multiple synchronous nonmembranous-type BCAs of the unilateral parotid gland is a rare entity.
  • More extensive excision of the parotid gland tumor, careful macroscopic perioperative examination of the surgical specimen, and histologic evaluation of all surgical specimens might be necessary for reducing revision operations and surgical complications.
  • [MeSH-minor] Adenolymphoma / diagnosis. Aged. Diagnosis, Differential. Female. Humans. Tomography, X-Ray Computed

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  • (PMID = 17993904.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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45. Sun G, Hu Q, Huang X, Tang E: Sebaceous lymphadenoma of parotid gland in a child. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2009 Feb;107(2):253-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sebaceous lymphadenoma of parotid gland in a child.
  • Sebaceous lymphadenoma is a rare tumor presenting predominantly in the parotid gland.
  • Most sebaceous lymphadenomas are composed of variably sized sebaceous glands admixed with salivary ducts in a diffuse lymphoid background.
  • Reported here is a case of sebaceous lymphadenoma of the left parotid gland in a 16-year-old boy.
  • [MeSH-major] Adenolymphoma / pathology. Parotid Neoplasms / pathology. Sebaceous Gland Neoplasms / pathology

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  • (PMID = 19138644.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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46. Ozcan C, Apa DD, Aslan G, Gülhan S, Görür K: Mycobacterium tuberculosis infection within parotid gland Warthin tumor. J Craniofac Surg; 2008 Nov;19(6):1561-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mycobacterium tuberculosis infection within parotid gland Warthin tumor.
  • Tuberculosis of the parotid gland is extremely unusual.
  • Tuberculosis comprises 2.5% to 10% of parotid gland lesions.
  • Two clinical forms of parotid gland tuberculosis infection exist.
  • Most of these patients were diagnosed after parotid gland surgery and histopathologic evaluation.
  • Warthin tumor is a well-known benign neoplasm of the salivary glands.
  • It is the second most common tumor of the parotid gland.
  • Five cases with parotid gland tuberculosis within Warthin tumor were reported in the literature.
  • In this report, we present a new patient with parotid gland tuberculosis within the Warthin tumor.
  • This type parotid gland pathology is an extremely rare entity, and to the best of our knowledge, this is the second documented case using polymerase chain reaction.
  • [MeSH-major] Adenolymphoma / diagnosis. Parotid Diseases / diagnosis. Parotid Neoplasms / diagnosis. Tuberculosis, Oral / diagnosis
  • [MeSH-minor] Antitubercular Agents / therapeutic use. Biopsy. Contrast Media. DNA, Bacterial / analysis. Follow-Up Studies. Humans. Image Enhancement. Magnetic Resonance Imaging. Male. Middle Aged. Mycobacterium tuberculosis / genetics. Polymerase Chain Reaction. Tuberculoma / diagnosis

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  • (PMID = 19098552.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antitubercular Agents; 0 / Contrast Media; 0 / DNA, Bacterial
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47. Wagner M, Klussmann JP, Dirsch O, Rose VA, Guntinas-Lichius O, Theegarten D, Sudhoff H, Linder R: Low prevalence of transfusion transmitted virus (TTV)-like DNA sequences in cystadenolymphoma and pleomorphic adenoma of the salivary glands. Eur Arch Otorhinolaryngol; 2006 Aug;263(8):759-63
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Low prevalence of transfusion transmitted virus (TTV)-like DNA sequences in cystadenolymphoma and pleomorphic adenoma of the salivary glands.
  • The present study was conducted to determine whether TTV-like DNA sequence elements play a role in the pathogenesis of cystadenolymphoma or pleomorphic adenoma and if the parotid or the submandibular gland is a major source of TTV persistence.
  • Sixty-two archival salivary gland samples (16 cystadenolymphomas, 13 pleomorphic adenomas, and 33 controls) and 23 corresponding saliva samples were examined using a polymerase chain reaction (PCR) for TTV DNA.
  • TTV appears to be only a bystander in cystadenolymphoma, pleomorphic adenoma, and other salivary gland affections.
  • [MeSH-major] Adenolymphoma / virology. Adenoma, Pleomorphic / virology. DNA, Viral / analysis. Salivary Gland Neoplasms / virology. Torque teno virus / genetics
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Base Sequence. Case-Control Studies. Female. Humans. Immunohistochemistry. Male. Middle Aged. Molecular Sequence Data. Parotid Gland / pathology. Parotid Gland / virology. Polymerase Chain Reaction. Prevalence. Saliva / virology. Sequence Analysis, DNA. Submandibular Gland / pathology. Submandibular Gland / virology

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  • [ErratumIn] Eur Arch Otorhinolaryngol. 2006 Nov;263(11):1060
  • (PMID = 16703387.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / DNA, Viral
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48. Gierek T, Majzel K, Jura-Szołtys E, Slaska-Kaspera A, Witkowska M, Klimczak-Gołab L: [A 20-year retrospective histoclinical analysis of parotid gland tumors in the ENT Department AM in Katowice]. Otolaryngol Pol; 2007;61(4):399-403

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A 20-year retrospective histoclinical analysis of parotid gland tumors in the ENT Department AM in Katowice].
  • INTRODUCTION: Salivary gland neoplasms represent the diverse group of tumours encountered by the head and neck surgeons.
  • MATERIAL AND METHODS: The study is analysis of 531 patients with parotid gland tumours in patients treated in ENT Department during 1986-2006.
  • The results of histological diagnosis were presented.
  • The most frequent tumour was pleomorphic adenoma--75% and adenolymphoma--16%.
  • Malignant tumours constituted 20% of all gland tumours.
  • [MeSH-major] Adenocarcinoma / epidemiology. Adenolymphoma / epidemiology. Adenoma, Pleomorphic / epidemiology. Parotid Neoplasms / epidemiology

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  • (PMID = 18260221.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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49. Ahn SH, Park SY: Sebaceous lymphadenocarcinoma of parotid gland. Eur Arch Otorhinolaryngol; 2006 Oct;263(10):940-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sebaceous lymphadenocarcinoma of parotid gland.
  • The sebaceous lymphadenocarcinoma of the salivary glands is extremely rare and represents carcinomatous transformation of sebaceous lymphadenoma.
  • We here report a fifth case of this tumor and the youngest age at diagnosis among reported cases.
  • [MeSH-major] Adenocarcinoma, Sebaceous / diagnosis. Adenolymphoma / diagnosis. Parotid Neoplasms / diagnosis. Sebaceous Gland Neoplasms / diagnosis

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  • (PMID = 16786364.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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50. Gallego L, Junquera L, Fresno MF: Non-sebaceous lymphadenoma of the parotid gland: immunohistochemical study and DNA ploidy analysis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2009 Apr;107(4):555-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Non-sebaceous lymphadenoma of the parotid gland: immunohistochemical study and DNA ploidy analysis.
  • Nonsebaceous lymphadenoma (NSL) is an unusual benign salivary gland tumor characterized by a predominant lymphoid background, dense lymphoid infiltrate, and absence of sebaceous differentiation.
  • We report an additional case of NSL arising in the parotid gland in 58-year-old female patient.
  • [MeSH-major] Adenolymphoma / genetics. Parotid Neoplasms / genetics

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  • (PMID = 19201224.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 68238-35-7 / Keratins
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51. Hayashi D, Tysome JR, Boyei E, Gluckman P, Barbaccia C: Sebaceous lymphadenoma of the parotid gland: report of two cases and review of the literature. Acta Otorhinolaryngol Ital; 2007 Jun;27(3):144-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sebaceous lymphadenoma of the parotid gland: report of two cases and review of the literature.
  • Sebaceous lymphadenoma is an unusual salivary gland neoplasm which is rarely correctly diagnosed pre-operatively in the parotid gland.
  • Two cases of sebaceous lymphadenoma are presented in which, in common with most cases reported in the literature, the correct pre-operative diagnosis was not made.
  • Although an uncommon tumour, it should be taken into consideration in the differential diagnosis of a solitary parotid mass.
  • [MeSH-major] Adenolymphoma / surgery. Parotid Neoplasms / surgery. Sebaceous Gland Neoplasms / surgery
  • [MeSH-minor] Aged. Diagnosis, Differential. Female. Humans. Male. Middle Aged

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  • (PMID = 17883193.001).
  • [ISSN] 0392-100X
  • [Journal-full-title] Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale
  • [ISO-abbreviation] Acta Otorhinolaryngol Ital
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 20
  • [Other-IDs] NLM/ PMC2640048
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52. Dardick I, Thomas MJ: Lymphadenoma of parotid gland: Two additional cases and a literature review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2008 Apr;105(4):491-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lymphadenoma of parotid gland: Two additional cases and a literature review.
  • For classification purposes, proper identification of infrequent and unique salivary gland tumors requires the gradual accumulation of a sufficient number of cases.
  • This report adds 2 additional cases occurring as a discrete, at least partially encapsulated nodule in the parotid gland.
  • [MeSH-major] Adenolymphoma / pathology. Parotid Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans. Male. Middle Aged. Treatment Outcome

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  • (PMID = 18329584.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 10
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53. Suwała P, Wilczyński K, Barnaś S, Prudlak E: [A rare case of multiple primary benign neoplasm of parotid gland: oncocytoma and adenolimphoma]. Otolaryngol Pol; 2009 Sep;63(7):89-92

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A rare case of multiple primary benign neoplasm of parotid gland: oncocytoma and adenolimphoma].
  • AIM OF THE WORK: The authors present unusually rare case primary multiple synchronicus benign tumor of the ipsilateral parotid gland: oncocytoma and Warthin's tumor, which is rare among occasionally occurred multiple tumors with different histology in the salivary glands.
  • MATERIAL AND METHOD: A 71-year-old man presented with the tumor in the right parotid gland.
  • We performed excision of the superficial lobe of the parotid gland.
  • The preoperative ultrasonography and macroscopic analysis of the removed parotid gland tissue revealed only one tumor recognised histopathologically as adenolimphoma, but upon histopathological examination Warthin's tumor proved to coexist with oncocytoma.
  • RESULTS AND CONCLUSIONS: In the ultrasonography examination some salivary glands tumors may not be recognised.
  • The histopathological examination is the ultimate method in recognising tumors, which are not detected in the preoperative diagnosis.
  • The superficial parotidectomy protects from the recrudescence of the superficial lobe of the parotid gland tumors.
  • The coexistence of the oncocytoma and Warthin's in one parotid gland is extremely rare.
  • [MeSH-major] Adenolymphoma / pathology. Adenoma, Oxyphilic / pathology. Neoplasms, Multiple Primary / pathology. Parotid Neoplasms / pathology
  • [MeSH-minor] Aged. Humans. Male. Parotid Gland / pathology. Rare Diseases. Treatment Outcome

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  • (PMID = 20564910.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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54. Yuan WH, Hsu HC, Chou YH, Hsueh HC, Tseng TK, Tiu CM: Gray-scale and color Doppler ultrasonographic features of pleomorphic adenoma and Warthin's tumor in major salivary glands. Clin Imaging; 2009 Sep-Oct;33(5):348-53
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gray-scale and color Doppler ultrasonographic features of pleomorphic adenoma and Warthin's tumor in major salivary glands.
  • Our aim was to assess the specific ultrasonic characteristics of pleomorphic adenoma and Warthin's tumor in major salivary glands.
  • [MeSH-major] Adenolymphoma / ultrasonography. Adenoma, Pleomorphic / ultrasonography. Echocardiography, Doppler, Color / methods. Salivary Gland Neoplasms / ultrasonography

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  • (PMID = 19712813.001).
  • [ISSN] 1873-4499
  • [Journal-full-title] Clinical imaging
  • [ISO-abbreviation] Clin Imaging
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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55. Tokyol C, Dilek FH, Aktepe F, Ayçiçek A, Altuntaş A: Oncocytic lipoadenoma of the parotid gland: a case report with fine needle aspiration cytology findings. Kulak Burun Bogaz Ihtis Derg; 2010 May-Jun;20(3):146-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Oncocytic lipoadenoma of the parotid gland: a case report with fine needle aspiration cytology findings.
  • Oncocytic lipoadenoma of the salivary gland is a rarely encountered tumor.
  • A 56-year-old man presented with a two-year history of a slow-growing mass of the left parotid gland.
  • A diagnosis of oncocytic lipoadenoma was made.
  • Oncocytic lipoadenoma should be considered in the differential diagnosis of oncocytic proliferations and oncocytic tumors in the parotid gland.
  • [MeSH-minor] Adenolymphoma / pathology. Adenolymphoma / surgery. Biopsy, Fine-Needle. Humans. Male. Middle Aged. Parotid Gland / surgery. Treatment Outcome

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  • (PMID = 20465541.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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56. Viguer JM, Vicandi B, Jiménez-Heffernan JA, López-Ferrer P, González-Peramato P, Castillo C: Role of fine needle aspiration cytology in the diagnosis and management of Warthin's tumour of the salivary glands. Cytopathology; 2010 Jun;21(3):164-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Role of fine needle aspiration cytology in the diagnosis and management of Warthin's tumour of the salivary glands.
  • Such therapeutic alternatives demand accurate diagnosis.
  • In order to determine whether fine needle aspiration cytology (FNAC) is capable of rendering such a minimally invasive diagnosis, we evaluated its accuracy and diagnostic parameters in a large series of histologically proven cases of WT.
  • METHODS: A cytohistological study of 116 salivary tumours from 110 patients (four WT were bilateral) with a histological or cytological diagnosis of WT.
  • RESULTS: Histology confirmed the cytological diagnosis in 103 of 114 tumours (90.4%).
  • In 11 cases of WT there was an erroneous or non-representative cytological diagnosis.
  • CONCLUSIONS: FNAC offers the possibility of a reliable diagnosis of WT.
  • [MeSH-major] Adenolymphoma / diagnosis. Adenolymphoma / therapy. Salivary Gland Neoplasms / diagnosis. Salivary Gland Neoplasms / therapy. Salivary Glands / pathology

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  • [CommentIn] Cytopathology. 2010 Dec;21(6):423; author reply 423 [20726866.001]
  • (PMID = 19744189.001).
  • [ISSN] 1365-2303
  • [Journal-full-title] Cytopathology : official journal of the British Society for Clinical Cytology
  • [ISO-abbreviation] Cytopathology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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57. Prades JM, Oletski A, Faye MB, Dumollard JM, Timoshenko AP, Veyret C, Peoc'h M, Martin C: [Parotid gland masses: diagnostic value of MR imaging with histopathologic correlations]. Morphologie; 2007 Mar;91(292):44-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Parotid gland masses: diagnostic value of MR imaging with histopathologic correlations].
  • BACKGROUND AND PURPOSE: The purpose of our study has been to describe the pre-operatively MR Imaging appearance of masses in the parotid gland which may be sources of clinical and radiological confusion.
  • Our routine MR Imaging study appears excellent not only for assessing the type and extent of benign salivary gland tumors and the relationship to adjacent structures, but also for determining whether the tumor is benign or malignant.
  • [MeSH-major] Magnetic Resonance Imaging. Parotid Neoplasms / diagnosis
  • [MeSH-minor] Adenolymphoma / diagnosis. Adenolymphoma / pathology. Adenoma, Pleomorphic / diagnosis. Adenoma, Pleomorphic / pathology. Adult. Aged. Aged, 80 and over. Carcinoma / diagnosis. Carcinoma / pathology. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Parotitis / diagnosis

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  • (PMID = 17652005.001).
  • [ISSN] 1286-0115
  • [Journal-full-title] Morphologie : bulletin de l'Association des anatomistes
  • [ISO-abbreviation] Morphologie
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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58. Klasser GD, Epstein JB, Utsman R, Yao M, Nguyen PH: Parotid gland squamous cell carcinoma invading the temporomandibular joint. J Am Dent Assoc; 2009 Aug;140(8):992-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Parotid gland squamous cell carcinoma invading the temporomandibular joint.
  • BACKGROUND: Tumor invasion of the temporomandibular joint from the parotid gland is rare.
  • The authors present case reports of two patients with parotid gland masses accompanied by pain, dysfunction and other symptoms not consistent with musculoskeletal disorders.
  • In both cases, clinicians initially reached an incorrect diagnosis and treated the masses as if they were TMDs, which delayed a definitive diagnosis and provision of appropriate treatment.
  • CONCLUSIONS: Dentists must take a thorough patient history, perform a detailed clinical examination and request proper radiographic imaging, when necessary, to render an accurate diagnosis and avoid mistreatment.
  • If dentists are in doubt about a diagnosis, referral to the appropriate specialist should be considered.
  • CLINICAL IMPLICATIONS: A thorough history, a comprehensive clinical examination and an understanding of salivary gland disorders should facilitate an accurate initial diagnosis, allowing delivery of the appropriate and necessary medical treatment.
  • [MeSH-minor] Adenolymphoma / pathology. Aged. Biopsy, Fine-Needle. Diagnosis, Differential. Ear Canal / pathology. Ear Neoplasms / secondary. Facial Pain / diagnosis. Follow-Up Studies. Humans. Male. Mandibular Condyle / pathology. Neoplasm Invasiveness. Neoplasm Recurrence, Local / pathology

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  • (PMID = 19654251.001).
  • [ISSN] 1943-4723
  • [Journal-full-title] Journal of the American Dental Association (1939)
  • [ISO-abbreviation] J Am Dent Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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59. Rawlinson NJ, Almarzooqi S, Nicol K: Sebaceous lymphadenoma of the parotid gland in a 13-year-old girl: a case report. Head Neck Pathol; 2010 Jun;4(2):144-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sebaceous lymphadenoma of the parotid gland in a 13-year-old girl: a case report.
  • Sebaceous lymphadenoma is a benign rare tumor of the salivary gland.
  • [MeSH-major] Adenolymphoma / pathology. Parotid Neoplasms / pathology. Sebaceous Gland Neoplasms / pathology
  • [MeSH-minor] Adenocarcinoma, Sebaceous / diagnosis. Adolescent. Carcinoma, Mucoepidermoid / diagnosis. Diagnosis, Differential. Female. Humans. Lymphoma / diagnosis

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  • [Cites] Acta Otorhinolaryngol Ital. 2007 Jun;27(3):144-6 [17883193.001]
  • [Cites] Ann R Coll Surg Engl. 2007 May;89(4):1-3 [17535604.001]
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  • (PMID = 20512641.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2878632
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60. Kwon YD, Biesterfeld S, Hansen T, Schwerdtfeger A, Kunkel M: Lymphadenomatous carcinoma of the sublingual gland: report of a first case in an unusual localization. Head Neck; 2008 Oct;30(10):1394-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lymphadenomatous carcinoma of the sublingual gland: report of a first case in an unusual localization.
  • BACKGROUND: Lymphadenomatous carcinoma of the salivary gland is a very rare tumor, which hitherto occurred exclusively in the parotid gland.
  • This report describes a case of lymphadenomatous carcinoma of the sublingual gland, which is thought to be the first report of this special entity.
  • [MeSH-major] Adenolymphoma / pathology. Carcinoma, Adenoid Cystic / pathology. Sublingual Gland Neoplasms / pathology

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  • [Copyright] Copyright (c) 2008 Wiley Periodicals, Inc. Head Neck 2008.
  • (PMID = 18327777.001).
  • [ISSN] 1097-0347
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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61. Colella G, Biondi P, Itro A, Compilato D, Campisi G: Warthin's tumor distribution within the parotid gland. A feasible etiologic source from lymph nodal tissue. Minerva Stomatol; 2010 May;59(5):245-9, 250-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Warthin's tumor distribution within the parotid gland. A feasible etiologic source from lymph nodal tissue.
  • AIM: Warthin's tumor (WT) is the second commonest parotid gland neoplasm after pleomorphic adenoma (PA).
  • It mainly arises from the lower pole of the superficial parotid lobe (i.e., tail of gland), a site with the greatest distribution of intra-parotid lymph nodes, and its definitive etiopathogenesis is still unclear.
  • The aim of this study was to support the strict topic and etiologic link hypothesised between this tumor and the intraparotid lymph nodes, as being massively present in the tail, by assessing the WT distribution within the parotid gland.
  • In all sample, staging of parotid gland tumors was defined by sonography and magnetic resonance imaging.
  • CONCLUSION: Since the tail has been well known to present the greatest distribution of intra-parotid lymph nodes, our clinical findings on WT parotid localization could suggest the possible origin of this tumor from epithelial salivary gland ductal inclusions, as being likely entrapped during embryogenesis within the intra-parotid lymph nodes, and could support the hypothesis of a heterotopy in the pathogenesis of WT.
  • However, this suggestive hypothesis based only on clinical and "topographic" data should be confirmed by histopathological studies about the presence of the salivary ductal elements trapped within the intra-parotid lymph nodes.
  • [MeSH-major] Adenolymphoma / pathology. Parotid Neoplasms / pathology

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  • (PMID = 20502429.001).
  • [ISSN] 0026-4970
  • [Journal-full-title] Minerva stomatologica
  • [ISO-abbreviation] Minerva Stomatol
  • [Language] eng; ita
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Italy
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62. Seethala RR, LiVolsi VA, Baloch ZW: Relative accuracy of fine-needle aspiration and frozen section in the diagnosis of lesions of the parotid gland. Head Neck; 2005 Mar;27(3):217-23
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Relative accuracy of fine-needle aspiration and frozen section in the diagnosis of lesions of the parotid gland.
  • BACKGROUND: Both fine-needle aspiration (FNA) and frozen section (FS), although useful in preoperative and intraoperative management, have their advantages and pitfalls when used in the diagnosis of salivary gland lesions.
  • Herein, we determine the relative accuracies of both FNA and FS in the diagnosis of salivary gland lesions.
  • METHODS: We reviewed a cohort of 220 cases of parotid gland FNA with histologic follow-up; FS was performed in 57 cases (26%).
  • The sensitivity, specificity, and accuracy of FNA and FS were determined with respect to the final histologic diagnosis.
  • For these calculations, benign diagnosis was considered negative, whereas a malignant diagnosis was considered positive.
  • The FS was able to change to benign four diagnoses that were malignant by FNA and provide a diagnosis for five nondiagnostic FNAs.
  • Hence, both techniques are complementary to each other in the diagnosis of salivary gland lesions.
  • [MeSH-minor] Adenolymphoma / pathology. Biopsy, Needle. Carcinoma, Mucoepidermoid / pathology. Frozen Sections. Humans. Retrospective Studies. Sensitivity and Specificity

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  • [Copyright] 2005 Wiley Periodicals, Inc.
  • (PMID = 15672359.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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63. Habermann CR, Arndt C, Graessner J, Diestel L, Petersen KU, Reitmeier F, Ussmueller JO, Adam G, Jaehne M: Diffusion-weighted echo-planar MR imaging of primary parotid gland tumors: is a prediction of different histologic subtypes possible? AJNR Am J Neuroradiol; 2009 Mar;30(3):591-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diffusion-weighted echo-planar MR imaging of primary parotid gland tumors: is a prediction of different histologic subtypes possible?
  • BACKGROUND AND PURPOSE: Our aim was to determine the value of echo-planar diffusion-weighted MR imaging (epiDWI) in differentiating various types of primary parotid gland tumors.
  • MATERIALS AND METHODS: One hundred forty-nine consecutive patients with suspected tumors of the parotid gland were examined with an epiDWI sequence by using a 1.5T unit.
  • Histologic diagnosis was obtained in every patient.
  • RESULTS: In 136 patients, a primary parotid gland tumor was confirmed by histology.
  • ADC values of Warthin tumors were different from those of myoepithelial adenomas, lipomas, and salivary duct carcinomas (P < .001, 0.013, and .037, respectively).
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Echo-Planar Imaging. Myoepithelioma / pathology. Parotid Gland / pathology
  • [MeSH-minor] Adenolymphoma / pathology. Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Basal Cell / pathology. Carcinoma, Mucoepidermoid / pathology. Diagnosis, Differential. Female. Humans. Lipoma / pathology. Male. Middle Aged. Prospective Studies. Salivary Gland Neoplasms / pathology. Young Adult

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  • (PMID = 19131405.001).
  • [ISSN] 1936-959X
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
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64. Lin C, Li J, Lu N: [Analysis of 2161 cases of neoplasm in oral maxillofacial region in Xinjiang]. Zhonghua Kou Qiang Yi Xue Za Zhi; 2010 Sep;45(9):553-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The most common benign tumors were pleomorphic adenoma, hemangioma, papilloma, adenolymphoma and ameloblastoma.
  • The most common malignant tumors of salivary gland were adenoid cystic carcinoma.
  • The most common sites of malignant tumors were tongue, lip, parotiod gland and buccal mucosa.
  • Adenoid cystic carcinoma was more common than other salivary originated tumors.
  • [MeSH-minor] Adenolymphoma. Adenoma, Pleomorphic. Ameloblastoma. Carcinoma, Adenoid Cystic / epidemiology. Carcinoma, Adenoid Cystic / pathology. Carcinoma, Squamous Cell / epidemiology. Carcinoma, Squamous Cell / pathology. China / epidemiology. Face. Humans. Incidence. Mouth Mucosa. Odontogenic Tumors. Retrospective Studies. Salivary Gland Neoplasms

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  • (PMID = 21122451.001).
  • [ISSN] 1002-0098
  • [Journal-full-title] Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
  • [ISO-abbreviation] Zhonghua Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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65. Srivastava S, Nadelman C: Synchronous ipsilateral Warthin tumor encased by a separate mucoepidermoid carcinoma of the parotid gland: a case report and review of the literature. Diagn Cytopathol; 2010 Jul;38(7):533-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Synchronous ipsilateral Warthin tumor encased by a separate mucoepidermoid carcinoma of the parotid gland: a case report and review of the literature.
  • Fine-needle aspiration (FNA) is a cost effective and low morbidity procedure in the initial assessment of salivary gland tumors.
  • However, cytological assessment of ipsilateral synchronous tumors (which make up less than 0.3% of all salivary gland neoplasms) may pose diagnostic challenges.
  • Another striking feature seen was the presence of chronic sialadenitis in the surrounding nonneoplastic salivary gland.
  • Traditionally, there has been diagnostic difficulty when dealing with synchronous tumors of the salivary gland and the background of chronic sialadenitis may further complicate the diagnosis.
  • FNA is very helpful and can give important cues to the diagnosis.
  • [MeSH-major] Adenolymphoma / complications. Adenolymphoma / pathology. Carcinoma, Mucoepidermoid / complications. Carcinoma, Mucoepidermoid / pathology. Parotid Gland / pathology. Parotid Neoplasms / complications. Parotid Neoplasms / pathology

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  • [Copyright] (c) 2009 Wiley-Liss, Inc.
  • (PMID = 20027619.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 40
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66. Faur A, Lazăr E, Cornianu M, Dema A, Vidita CG, Găluşcan A: Warthin tumor: a curious entity--case reports and review of literature. Rom J Morphol Embryol; 2009;50(2):269-73
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Warthin tumor was first described in the American literature, by Aldred Warthin, in 1929, the pathologist who named this tumor papillary cystadenoma lymphomatosum, but since than it was also knew as adenolymphoma, cystadenolymphoma, and Warthin tumor.
  • We reviewed the medical record of patients with salivary gland tumors diagnosed at County Hospital of Timisoara from 2002-2008.
  • The standard and the histological and immunohistochemical techniques highlighted the complex and variable microscopical appearance of Warthin tumor that the pathologist should consider when a diagnosis for this tumor is to be considered.
  • [MeSH-major] Adenolymphoma / pathology. Salivary Gland Neoplasms / pathology

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  • (PMID = 19434322.001).
  • [ISSN] 1220-0522
  • [Journal-full-title] Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
  • [ISO-abbreviation] Rom J Morphol Embryol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Romania
  • [Chemical-registry-number] 0 / Antigens, CD20; 0 / Mucins
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67. Freedman LS, Oberman B, Sadetzki S: Using time-dependent covariate analysis to elucidate the relation of smoking history to Warthin's tumor risk. Am J Epidemiol; 2009 Nov 1;170(9):1178-85
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The authors aimed to elucidate the relation of the time-dependent smoking history parameters--age at smoking initiation and smoking intensity, duration, and latency--to the risk of Warthin's tumor, a benign tumor of the salivary gland for which cigarette smoking is a strong risk factor.
  • They studied 117 cases of Warthin's tumor and 336 matched controls included in an Israeli nationwide case-control study of parotid gland tumors conducted from 2002 to 2003 by using the Cox regression model with time-dependent covariates, with age as the time axis.
  • [MeSH-major] Adenolymphoma / etiology. Salivary Gland Neoplasms / etiology. Smoking / adverse effects

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  • (PMID = 19755633.001).
  • [ISSN] 1476-6256
  • [Journal-full-title] American journal of epidemiology
  • [ISO-abbreviation] Am. J. Epidemiol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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68. Gorai S, Numata T, Kawada S, Nakano M, Tamaru J, Kobayashi T: Malignant lymphoma arising from heterotopic Warthin's tumor in the neck: case report and review of the literature. Tohoku J Exp Med; 2007 Jun;212(2):199-205
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Warthin's tumor (WT), so-called adenolymphoma, is a benign salivary gland tumor with both epithelial and lymphoid histological characteristics, so the histogenesis remains unclear.
  • The histological diagnosis was malignant lymphoma, diffuse large B-cell type, arising from heterotopic WT.
  • [MeSH-major] Adenolymphoma / pathology. Lymphoma, Large B-Cell, Diffuse / etiology. Neck / pathology

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  • (PMID = 17548964.001).
  • [ISSN] 0040-8727
  • [Journal-full-title] The Tohoku journal of experimental medicine
  • [ISO-abbreviation] Tohoku J. Exp. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antigens, CD20; 0 / Antigens, CD79; 0 / B-Cell-Specific Activator Protein; 0 / PAX5 protein, human
  • [Number-of-references] 28
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69. Loy AH, Putti TC, Tan LK: Cyclooxygenase-2 expression in Warthin's tumour. J Laryngol Otol; 2005 Jul;119(7):515-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • There was also overexpression of COX-2 in the salivary duct system of normal parotid tissue.
  • Our findings support the hypothesis that Warthin's tumours originate from heterotopic ductal epithelial cells of the parotid gland.
  • [MeSH-major] Adenolymphoma / enzymology. Cyclooxygenase 2 / analysis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Epithelium / enzymology. Humans. Immunohistochemistry / methods. Lymphoid Tissue / enzymology. Male. Middle Aged. Parotid Gland / enzymology. Salivary Ducts / enzymology

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  • (PMID = 16175974.001).
  • [ISSN] 0022-2151
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] EC 1.14.99.1 / Cyclooxygenase 2
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70. Zhang DK, Guo ZM, Zhang Q, Zeng ZY, Chen FJ, Chen WK, Li H, Wang SL: [Application of helix water jet to parotid surgery]. Ai Zheng; 2008 Jan;27(1):105-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Duration of operation, postoperative drainage volume, postoperative hospitalization, and occurrence of postoperative complications, such as facial nerve dysfunction and salivary fistula, of the 2 groups were compared.
  • Of the 43 patients in water jet group, 6 (14.0%) had grade II facial nerve dysfunction and 1 (2.3%) had grade III facial nerve dysfunction; of the 36 patients in control group, 5 (13.9%) had grade II facial nerve dysfunction, 2 (5.6%) had grade III facial nerve dysfunction, 1 (2.8%) had grade IV facial nerve dysfunction and 1 (2.8%) had salivary fistula.
  • [MeSH-major] Adenoma, Pleomorphic / surgery. Dissection / methods. Parotid Gland / surgery. Parotid Neoplasms / surgery
  • [MeSH-minor] Adenolymphoma / pathology. Adenolymphoma / surgery. Adolescent. Adult. Aged. Carcinoma, Mucoepidermoid / pathology. Carcinoma, Mucoepidermoid / surgery. Facial Paralysis / etiology. Female. Follow-Up Studies. Humans. Hydrostatic Pressure. Male. Middle Aged. Retrospective Studies. Salivary Gland Fistula / etiology. Young Adult

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  • (PMID = 18184476.001).
  • [Journal-full-title] Ai zheng = Aizheng = Chinese journal of cancer
  • [ISO-abbreviation] Ai Zheng
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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71. Prieto-Rodríguez M, Artés-Martínez MJ, Navarro-Hervás M, Camañas-Sanz A, Vera-Sempere FJ: Cytological characteristics of acinic cell carcinoma (ACC) diagnosed by fine-needle aspiration biopsy (FNAB). A study of four cases. Med Oral Patol Oral Cir Bucal; 2005 Mar-Apr;10(2):103-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • DISCUSSION: FNAB provides essential information on the diagnostic-therapeutic management of salivary gland tumors; this methodology is highly sensitive in its diagnostic efficacy.
  • The diagnosis of ACCs frequently presents difficulties, owing to the great cytologic similarity of the tumor cells with the normal acinar component of the salivary gland.
  • The differential diagnosis is considered, fundamentally, with clear cell carcinomas, mucoepidermoid carcinomas, Warthin s tumor, and oncocytomas.
  • [MeSH-major] Carcinoma, Acinar Cell / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands / pathology
  • [MeSH-minor] Adenolymphoma / pathology. Aged. Aged, 80 and over. Biopsy, Fine-Needle. Child. Diagnosis, Differential. Female. Humans. Male. Middle Aged

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  • (PMID = 15735541.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng; spa
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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72. Fehr A, Röser K, Belge G, Löning T, Bullerdiek J: A closer look at Warthin tumors and the t(11;19). Cancer Genet Cytogenet; 2008 Jan 15;180(2):135-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The translocation t(11;19)(q21;p13) has been described in mucoepidermoid carcinoma (MEC) and rarely in Warthin tumors (WT), both tumors of the salivary gland.
  • We therefore conclude that the presence of the t(11;19)(q21;p13) rearrangement favors a diagnosis of MEC.
  • [MeSH-major] Adenolymphoma / genetics. Chromosomes, Human, Pair 11. Chromosomes, Human, Pair 19. Salivary Gland Neoplasms / genetics. Translocation, Genetic
  • [MeSH-minor] Carcinoma, Mucoepidermoid / diagnosis. Carcinoma, Mucoepidermoid / genetics. Cell Line, Tumor. DNA-Binding Proteins / genetics. Gene Expression Regulation, Neoplastic. Humans. Nuclear Proteins / genetics. Oncogene Proteins, Fusion / genetics. Transcription Factors / genetics

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  • (PMID = 18206539.001).
  • [ISSN] 0165-4608
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CRTC1 protein, human; 0 / DNA-Binding Proteins; 0 / MAML2 protein, human; 0 / Nuclear Proteins; 0 / Oncogene Proteins, Fusion; 0 / Transcription Factors
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73. Beutner D, Wittekindt C, Dinh S, Huttenbrink KB, Guntinas-Lichius O: Impact of lateral parotidectomy for benign tumors on quality of life. Acta Otolaryngol; 2006 Oct;126(10):1091-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CONCLUSION: This study supports the use of lateral parotidectomy as a safe and standardized type of surgery for benign parotid gland disease.
  • OBJECTIVE: To assess quality of life in patients with benign salivary gland tumors who underwent lateral parotidectomy.
  • PATIENTS AND METHODS: Fifty-one patients suffering from benign parotid gland disease were included in this prospective study.
  • [MeSH-major] Adenolymphoma / surgery. Adenoma / surgery. Adenoma, Pleomorphic / surgery. Parotid Gland / surgery. Parotid Neoplasms / surgery. Quality of Life

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  • (PMID = 16923716.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Norway
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74. Ye WM, Zhu HG, Zheng JW, Wang XD, Zhao W, Zhong LP, Zhang ZY: Use of allogenic acellular dermal matrix in prevention of Frey's syndrome after parotidectomy. Br J Oral Maxillofac Surg; 2008 Dec;46(8):649-52
Genetic Alliance. consumer health - Frey's Syndrome.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHOD: We studied a total of 168 patients with benign parotid gland tumours, including 89 patients with pleomorphic adenoma; 45 with Warthin tumour; 17 with basal cell adenoma; and 17 with miscellaneous tumours.
  • Salivary fistulas developed in 18 patients from the control group (17%), but in only 1 patient from the ADM group (2%).
  • [MeSH-major] Collagen. Oral Surgical Procedures / adverse effects. Parotid Gland / surgery. Skin, Artificial. Sweating, Gustatory / prevention & control
  • [MeSH-minor] Adenolymphoma / surgery. Adenoma / surgery. Adenoma, Pleomorphic / surgery. Adolescent. Adult. Aged. Humans. Middle Aged. Parotid Neoplasms / surgery. Salivary Gland Fistula / etiology. Salivary Gland Fistula / prevention & control. Young Adult

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  • (PMID = 18547692.001).
  • [ISSN] 1532-1940
  • [Journal-full-title] The British journal of oral & maxillofacial surgery
  • [ISO-abbreviation] Br J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Controlled Clinical Trial; Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0 / Alloderm; 9007-34-5 / Collagen
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75. Honda K, Okada F, Ando Y, Matsumoto S, Mori H: Sebaceous lymphadenoma demonstrated by CT and MRI. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 May;109(5):e59-62
MedlinePlus Health Information. consumer health - MRI Scans.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Sebaceous differentiation in normal salivary gland tissue is known to occur, but primary sebaceous neoplasms of the salivary gland are extremely rare.
  • We describe a 75-year-old man with a sebaceous lymphadenoma of the right salivary gland.
  • [MeSH-major] Adenolymphoma / diagnosis. Magnetic Resonance Imaging. Parotid Neoplasms / diagnosis. Sebaceous Gland Neoplasms / diagnosis. Tomography, X-Ray Computed
  • [MeSH-minor] Aged. Contrast Media. Diagnosis, Differential. Humans. Male. Radiographic Image Enhancement

  • MedlinePlus Health Information. consumer health - CT Scans.
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  • [Copyright] Copyright (c) 2010 Mosby, Inc. All rights reserved.
  • (PMID = 20416520.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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76. Ascani G, Pieramici T, Rubini C, Messi M, Balercia P: Synchronous bilateral Warthin's tumours of the parotid glands: a case report. Acta Otorhinolaryngol Ital; 2010 Dec;30(6):310-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Warthin's tumour is the most frequent monomorphic adenoma of the major salivary glands, representing about 2-15% of all parotid tumours.
  • [MeSH-major] Adenolymphoma / pathology. Neoplasms, Multiple Primary / pathology. Parotid Neoplasms / pathology

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  • [Cites] Eur Arch Otorhinolaryngol. 2008 Dec;265(12):1573-5 [18301907.001]
  • [Cites] Br J Oral Maxillofac Surg. 2006 Oct;44(5):397-401 [16207507.001]
  • [Cites] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Mar;101(3):333-8 [16504867.001]
  • [Cites] Acta Otolaryngol. 2006 Dec;126(11):1213-7 [17050316.001]
  • [Cites] Acta Otorhinolaryngol Belg. 1998;52(1):55-7 [9581198.001]
  • [Cites] Br J Oral Maxillofac Surg. 1993 Feb;31(1):43-4 [8431414.001]
  • [Cites] Int J Oral Maxillofac Surg. 2004 Sep;33(6):531-4 [15308250.001]
  • [Cites] Oral Oncol. 2002 Jan;38(1):35-40 [11755819.001]
  • [Cites] Br J Oral Maxillofac Surg. 2007 Apr;45(3):238-9 [16207506.001]
  • [Cites] Eur J Cancer B Oral Oncol. 1995 May;31B(3):197-201 [7549761.001]
  • (PMID = 21808453.001).
  • [ISSN] 1827-675X
  • [Journal-full-title] Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale
  • [ISO-abbreviation] Acta Otorhinolaryngol Ital
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC3146325
  • [Keywords] NOTNLM ; Bilateral tumours / Multifocal tumours / Parotid gland / Salivary gland tumours / Warthin's tumour
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77. Banich J, Reyes CV, Bier-Laning C: Sebaceous lymphadenoma identified by fine needle aspiration biopsy: a case report. Acta Cytol; 2007 Mar-Apr;51(2):211-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Sebaceous lymphadenoma of the parotid gland is a rare benign neoplasm.
  • This is the first reported case of fine needle aspiration biopsy (FNAB) findings for sebaceous lymphadenoma of the parotid gland.
  • It revealed lymphoid and salivary gland parenchymal cells.
  • The surgical specimen of the parotid mass confirmed the diagnosis of sebaceous lymphadenoma on the tissue section.
  • Though the definitive diagnosis of any parotid mass requires tissue, generally obtained via parotidectomy, an FNAB diagnosis can be useful in counseling a patient prior to definitive biopsy.
  • [MeSH-major] Adenolymphoma / pathology. Parotid Gland / pathology. Parotid Neoplasms / pathology. Sebaceous Gland Neoplasms / pathology
  • [MeSH-minor] Biopsy, Fine-Needle. Diagnosis, Differential. Digestive System Surgical Procedures. Facial Nerve Injuries / etiology. Facial Nerve Injuries / physiopathology. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Postoperative Complications / etiology. Postoperative Complications / physiopathology. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 17425206.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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78. Karthikeya P, Mahima VG, Shalini K: Papillary cystadenoma lymphomatosum: case report and review of literature. Indian J Dent Res; 2005 Oct-Dec;16(4):153-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Papillary Cystadenoma Lymphomatosum or Warthin's tumour is a unique neoplasm arising almost exclusively in the parotid salivary gland and is composed of oncocytic epithelium with a prominent lymphoid infiltrate.
  • This article presents a typical case arising in the right parotid gland of a 73-year-old male with review of literature of this rare tumour.
  • [MeSH-major] Adenolymphoma / diagnosis. Parotid Neoplasms / diagnosis
  • [MeSH-minor] Aged. Diagnosis, Differential. Humans. Male

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  • (PMID = 16761709.001).
  • [ISSN] 0970-9290
  • [Journal-full-title] Indian journal of dental research : official publication of Indian Society for Dental Research
  • [ISO-abbreviation] Indian J Dent Res
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] India
  • [Number-of-references] 26
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79. Yu H, Liu D, Li C, Huang X, Zhong W: [Clinical application of postauricular muscular fasciae-periosteal flap and modified unwrinkle incision in parotidectomy]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2009 Oct;23(10):1167-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: From January 2006 to August 2008, 28 patients with benign lesions of parotid gland were treated.
  • There were 17 males and 11 females aged 19 to 79 years old (average 50 years old), including 20 cases of mixed tumor, 5 cases of adenolymphoma, 1 case of branchial cleft cyst, 1 case of eosinophilic hyperplastic lymphogranuloma, and 1 case of myoepithelioma.
  • Parotid gland and tumor mass were resected with postauricular incision hidden within the hairline, introcession defect (3.0 cm x 2.0 cm x 1.0 cm-3.5 cm x 2.5 cm x 1.5 cm) were repaired with simultaneously adopting postauricular muscular fasciae-periosteal flap (4.0 cm x 3.0 cm x 1.0 cm-5.0 cm x 4.0 cm x 1.5 cm) by turning the pedicle flap 180 degrees.
  • No salivary fistula, facial paralysis, and earlobe numbness occurred.
  • [MeSH-major] Fascia / transplantation. Parotid Gland / surgery. Parotid Neoplasms / surgery. Rhytidoplasty / methods

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  • (PMID = 19957830.001).
  • [ISSN] 1002-1892
  • [Journal-full-title] Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
  • [ISO-abbreviation] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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80. Teymoortash A, Werner JA: Tissue that has lost its track: Warthin's tumour. Virchows Arch; 2005 Jun;446(6):585-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The origin of cystadenolymphoma (Warthin's tumour) of the parotid gland is unknown.
  • According to the most favoured hypothesis, Warthin's tumour results from the proliferation of salivary gland ductal cells that were entrapped in parotid lymph nodes during embryonal life.
  • [MeSH-major] Adenolymphoma / pathology. Parotid Neoplasms / pathology

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  • [CommentIn] Virchows Arch. 2006 Jun;448(6):877-8 [16609912.001]
  • (PMID = 15912361.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 30
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81. Becelli R, Morello R, Renzi G, Dominici C: Warthin's tumor of the hard palate. J Craniofac Surg; 2007 Sep;18(5):1182-4
Genetic Alliance. consumer health - Warthin's tumor.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Warthin's Tumor (WT) or papillary cystadenoma lymphomatosum is typically located in parotid gland.
  • Extraparotid localization of WTs (EPWT) was rarely described in ectopic salivary tissue in the latero-cervical and para-parotid lymph nodes.
  • With consideration of uncertain pre-surgical diagnosis obtained with FNAC, intraoperative histologic examination of frozen sections was planned.
  • [MeSH-major] Adenolymphoma / pathology. Palatal Neoplasms / pathology. Palate, Hard / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Treatment Outcome

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  • (PMID = 17912110.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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82. Bahar G, Dudkiewicz M, Feinmesser R, Joshua BZ, Braslavsky D, Popovtzer A, Galil D, Shpitzer T: Acute parotitis as a complication of fine-needle aspiration in Warthin's tumor. A unique finding of a 3-year experience with parotid tumor aspiration. Otolaryngol Head Neck Surg; 2006 Apr;134(4):646-9
Genetic Alliance. consumer health - Warthin's tumor.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE/HYPOTHESIS: Fine needle aspiration (FNA) is an accurate, cost-effective tool for the study of salivary gland lesions.
  • Although complications are extremely rare, salivary gland FNA can lead to hemorrhage, facial nerve injury, and cellulitis at the needle puncture site.
  • We review our recent experience with FNA of the parotid gland, focusing on possible complications and pitfalls.
  • STUDY DESIGN AND SETTING: The medical records of all patients who underwent FNA of the parotid gland from 2000 to 2002 in the Department of Otolaryngology-Head and Neck Surgery of a major tertiary-care referral center were reviewed.
  • Cytological results were compared to the histological diagnosis and complications were recorded.
  • Our findings indicate that FNA is a strong and reliable tool in the investigation of the salivary glands.
  • Nevertheless, when Warthin's tumor is clinically suspected on the basis of its location (tail of the parotid gland), cystic texture, patient sex (male) and age, one should consider parotitis as a possible complication.
  • [MeSH-major] Adenolymphoma / pathology. Parotid Neoplasms / pathology. Parotitis / etiology

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  • (PMID = 16564390.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents
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83. Taylor TR, Cozens NJ, Robinson I: Warthin's tumour: a retrospective case series. Br J Radiol; 2009 Nov;82(983):916-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Warthin's tumour (benign cystadenolymphoma) is the second most common salivary gland tumour after pleomorphic salivary adenoma, and it is commonly encountered in routine head and neck ultrasonography.
  • Tissue diagnosis can be achieved by fine-needle aspiration.
  • [MeSH-major] Adenolymphoma / pathology. Parotid Gland / pathology. Parotid Neoplasms / pathology

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  • (PMID = 19433486.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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84. O'Neill ID: t(11;19) translocation and CRTC1-MAML2 fusion oncogene in mucoepidermoid carcinoma. Oral Oncol; 2009 Jan;45(1):2-9
MedlinePlus Health Information. consumer health - Salivary Gland Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Mucoepidermoid carcinoma (MEC) is a relatively uncommon carcinoma of variable histology that can involve many tissue types, most commonly major and minor salivary glands and the tracheo-bronchial tree.
  • [MeSH-major] Carcinoma, Mucoepidermoid / genetics. Lung Neoplasms / genetics. Oncogene Proteins, Fusion / genetics. Salivary Gland Neoplasms / genetics. Translocation, Genetic / genetics
  • [MeSH-minor] Adenolymphoma / genetics. Cell Cycle / genetics. Cell Line, Tumor. Chromosomes, Human, Pair 11 / genetics. Chromosomes, Human, Pair 19 / genetics. DNA-Binding Proteins / genetics. Female. Gene Expression Regulation, Neoplastic. Humans. Male. Nuclear Proteins / genetics. Transcription Factors / genetics

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  • (PMID = 18486532.001).
  • [ISSN] 1879-0593
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / CRTC1 protein, human; 0 / DNA-Binding Proteins; 0 / MAML2 protein, human; 0 / Nuclear Proteins; 0 / Oncogene Proteins, Fusion; 0 / Transcription Factors
  • [Number-of-references] 77
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85. Steele NP, Sampogna D, Sessions RB: Kaposi's sarcoma of an intraparotid lymph node leading to a diagnosis of HIV. Laryngoscope; 2005 May;115(5):861-3
HIV InSite. treatment guidelines - Human Herpesvirus-8 .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Kaposi's sarcoma of an intraparotid lymph node leading to a diagnosis of HIV.
  • OBJECTIVE: Kaposi's sarcoma is a common malignancy in patients infected with HIV but is rarely seen in the major salivary glands.
  • If a patient is known to be HIV-positive, however, Kaposi's sarcoma must be considered in the differential diagnosis of salivary gland masses in addition to the benign and malignant neoplasms that occur in immunocompetent patients.
  • We present a unique case in which an otherwise healthy patient was diagnosed with HIV after resection of his enlarged parotid gland revealed Kaposi's sarcoma.
  • The patient's presentation, workup, and final diagnosis of Kaposi's sarcoma are discussed.
  • The patient underwent a right superficial parotidectomy for a suspected diagnosis of Warthin's tumor, given the bilaterality of the lesions.
  • CONCLUSIONS: Although Kaposi's sarcoma is common in AIDS patients, there are few case reports of this malignancy arising in the salivary glands.
  • Previously reported cases include salivary gland Kaposi's sarcoma in known HIV-positive patients and a handful of reports in patients without confirmed immunocompromise.
  • The patient presented here is unique because the diagnosis of parotid gland Kaposi's sarcoma led to a new diagnosis of HIV.
  • This interesting case reiterates the need for complete history taking and the inclusion of Kaposi's sarcoma in the differential diagnosis of salivary gland masses in the appropriate patient population.
  • [MeSH-major] HIV Seropositivity / diagnosis. Parotid Neoplasms / diagnosis. Sarcoma, Kaposi / diagnosis
  • [MeSH-minor] Adenolymphoma / diagnosis. Biopsy, Needle. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. Middle Aged

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  • MedlinePlus Health Information. consumer health - Kaposi's Sarcoma.
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  • (PMID = 15867654.001).
  • [ISSN] 0023-852X
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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86. While B, Whiteside OJ, Desai V, Gurr P: Sebaceous lymphadenoma: a case report and review of the literature. Ear Nose Throat J; 2010 Aug;89(8):E22-3
MedlinePlus Health Information. consumer health - MRI Scans.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Magnetic resonance imaging displayed a well-circumscribed lesion within the left parotid gland.
  • Sebaceous lymphadenomas of the salivary glands are rare, benign tumors that are effectively treated by complete excision.
  • The challenge that these tumors present lies in their accurate diagnosis.
  • We highlight the need for careful clinical and histologic diagnosis in tumors of the salivary glands.
  • [MeSH-major] Adenolymphoma / diagnosis. Magnetic Resonance Imaging. Parotid Neoplasms / diagnosis
  • [MeSH-minor] Aged, 80 and over. Diagnosis, Differential. Female. Humans. Lymphoma, Non-Hodgkin / diagnosis. Ultrasonography

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  • (PMID = 20737364.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
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87. O'Neill ID: New insights into the nature of Warthin's tumour. J Oral Pathol Med; 2009 Jan;38(1):145-9
MedlinePlus Health Information. consumer health - Salivary Gland Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenolymphoma / genetics. Oncogene Fusion / genetics. Salivary Gland Neoplasms / genetics. Translocation, Genetic / genetics

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  • (PMID = 18647217.001).
  • [ISSN] 1600-0714
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / CRCT1 protein, human; 0 / DNA-Binding Proteins; 0 / MAML2 protein, human; 0 / Nuclear Proteins; 0 / Proteins; 0 / Transcription Factors
  • [Number-of-references] 44
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88. Herce-López J, Salazar-Fernández CI, Mayorga-Jiménez F, Gallana-Alvarez S, Pérez-Sánchez JM: Synchronous unilateral parotid neoplasms. A case report. Med Oral Patol Oral Cir Bucal; 2009 Feb;14(2):E90-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The parotid gland is the most usual location of benign neoplasms affecting major salivary glands and quite often the recurrence of these tumours is noticed, specially in the case of pleomorphic adenoma.
  • The report describes a 55 year old female with a pleomorphic adenoma occurring synchronously with a Warthin's tumor within the superficial lobe of her left parotid gland.
  • [MeSH-major] Adenolymphoma. Adenoma, Pleomorphic. Neoplasms, Multiple Primary. Parotid Neoplasms

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  • (PMID = 19179956.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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89. Pietniczka-Załeska M, Dabrowska-Bień J: [Parotid tumors: a two-year experience of Otolaryngology Department at MSS Hospital in Warsaw]. Otolaryngol Pol; 2009 Sep;63(7):43-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • THE AIM OF THE STUDY: Tumors of the salivary glands represent about 3% of head and neck neoplasms.
  • Most of theme--up to 80%--originate from the parotid gland.
  • The aim of the study is to present current epidemiological data, most frequent complains, our surgical technique, histopathological diagnosis, complications rate and follow-up.
  • RESULTS: The frequency of incidence of benign tumours was 90% and the most frequent histopathological diagnosis was pleomorphic adenoma (49%) and adenolymphoma (42%).
  • The most frequent complication was sensory deficit about the cheek and ear (35%), temporary facial nerve paresis (5%), hematoma (1%), salivary fistula (1%).
  • CONCLUSION: Superficial and total parotidectomy are safe procedures of treatment in case of salivary gland tumors.

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  • (PMID = 20564899.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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90. Nouraei SA, Ismail Y, Ferguson MS, McLean NR, Milner RH, Thomson PJ, Welch AR: Analysis of complications following surgical treatment of benign parotid disease. ANZ J Surg; 2008 Mar;78(3):134-8
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Sialadenitis was a significant risk factor for facial nerve palsy and increased the incidence of salivary fistulas.
  • [MeSH-major] Facial Paralysis / epidemiology. Otorhinolaryngologic Surgical Procedures / adverse effects. Parotid Diseases / pathology. Parotid Diseases / surgery. Parotid Gland / surgery. Postoperative Complications / epidemiology
  • [MeSH-minor] Adenolymphoma / pathology. Adenolymphoma / surgery. Adolescent. Adult. Age Distribution. Aged. Aged, 80 and over. Biopsy, Needle. Cohort Studies. Female. Humans. Immunohistochemistry. Incidence. Male. Middle Aged. Prognosis. Retrospective Studies. Risk Assessment. Sex Distribution. Sialadenitis / pathology. Sialadenitis / surgery. South Australia / epidemiology

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  • (PMID = 18269474.001).
  • [ISSN] 1445-2197
  • [Journal-full-title] ANZ journal of surgery
  • [ISO-abbreviation] ANZ J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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91. Saussez S, de Leval L, Decaestecker C, Sirtaine N, Cludts S, Duray A, Chevalier D, André S, Gabius HJ, Remmelink M, Leroy X: Galectin fingerprinting in Warthin's tumors: lectin-based approach to trace its origin? Histol Histopathol; 2010 05;25(5):541-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Warthin's tumor of the parotid gland is assumed to originate from the proliferation of epithelial inclusions within parotid lymph nodes.
  • In that case, these cells are supposed to retain characteristics similar to common salivary gland ductal cells.
  • [MeSH-major] Adenolymphoma / metabolism. Galectins / metabolism. Parotid Neoplasms / metabolism

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  • (PMID = 20238293.001).
  • [ISSN] 1699-5848
  • [Journal-full-title] Histology and histopathology
  • [ISO-abbreviation] Histol. Histopathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Galectin 1; 0 / Galectin 3; 0 / Galectins; 0 / LGALS1 protein, human; 0 / LGALS7 protein, human; 0 / LGALS8 protein, human
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92. Roy S, Dhingra KK, Gupta P, Khurana N, Gupta B, Meher R: Acinic cell carcinoma with extensive neuroendocrine differentiation: a diagnostic challenge. Head Neck Pathol; 2009 Jun;3(2):163-8
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  • Primary salivary gland carcinoma with neuroendocrine differentiation is of rare occurrence, especially so in the parotid gland.
  • Contrast Enhanced Computed Tomography (CECT) suggested diagnosis of Pleomorphic Adenoma.
  • Immunoexpression of S-100, Neuron specific Enolase (NSE), Chromogranin A and Synaptophysin confirmed the diagnosis.
  • The possibility of neuroendocrine differentiation in a primary salivary gland tumor should be kept in mind whenever a salivary gland tumor shows only neuroendocrine histology.
  • [MeSH-minor] Adenolymphoma / pathology. Biopsy, Fine-Needle. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Middle Aged

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  • [Cites] Pathobiology. 1990;58(4):212-20 [1701303.001]
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  • (PMID = 19644544.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Acinic cell / Carcinoma / Chromogranin / Neuroendocrine / Parotid / Warthin’s
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93. Tsakiropoulou E, Konstantinidis I, Vital I, Triaridis S, Vital V: Ectopic Warthin's tumour presenting as a neck mass. B-ENT; 2008;4(2):111-5

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • INTRODUCTION: Warthin's tumour usually involves the parotid gland.
  • However, it can also arise from ectopic salivary tissue in the para-parotid and latero-cervical lymph nodes.
  • Computed tomography (CT) scanning (coronal, axial and sagittal sections) showed a cystic lesion in the right upper neck without connection to the major salivary glands (8 x 4 x 3 cm).
  • CONCLUSION: This neoplasm should be included in the differential diagnosis of cystic lesions of the neck.
  • Coronal and sagittal CT scans are necessary to accurately localize the tumour and to differentiate the diagnosis from earring lesions of the parotid tail.
  • [MeSH-major] Adenolymphoma / diagnosis. Parotid Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Follow-Up Studies. Humans. Male. Middle Aged. Oral Surgical Procedures / methods. Tomography, X-Ray Computed

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  • (PMID = 18681208.001).
  • [ISSN] 1781-782X
  • [Journal-full-title] B-ENT
  • [ISO-abbreviation] B-ENT
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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94. Shaw CK, Sood S, Bradley PJ, Krishnan S: Unusual mass in the parapharyngeal space: a Warthin's tumour. ANZ J Surg; 2006 Mar;76(3):193-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Most of the PPS tumours are salivary tumours (pleomorphic adenoma being the most frequent diagnosis), and are thought to originate from minor salivary glands or the deep lobe of the parotid gland.
  • Warthin's tumour, another benign salivary tumour involving the PPS has been rarely reported.
  • [MeSH-major] Adenolymphoma / pathology. Neoplasms, Second Primary / pathology. Parotid Neoplasms / pathology. Pharynx / pathology
  • [MeSH-minor] Aged. Female. Humans. Neoplasm Invasiveness. Parotid Gland / surgery. Tomography, X-Ray Computed

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  • (PMID = 16626365.001).
  • [ISSN] 1445-1433
  • [Journal-full-title] ANZ journal of surgery
  • [ISO-abbreviation] ANZ J Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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95. Masuda A, Nishikawa T, Yamamoto T, Kobayashi M: Distribution of DC-SIGN dendritic cells in the lymphoid stroma of Warthin's tumour; immunohistochemical analysis. Histopathology; 2006 Oct;49(4):433-5
MedlinePlus Health Information. consumer health - Salivary Gland Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenolymphoma / metabolism. Cell Adhesion Molecules / metabolism. Dendritic Cells / metabolism. Lectins, C-Type / metabolism. Receptors, Cell Surface / metabolism. Salivary Gland Neoplasms / metabolism

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  • (PMID = 16978211.001).
  • [ISSN] 0309-0167
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Letter
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Cell Adhesion Molecules; 0 / DC-specific ICAM-3 grabbing nonintegrin; 0 / Lectins, C-Type; 0 / Receptors, Cell Surface
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96. Siddaraju N, Roy SK, Bundele MM, Soundararaghavan J: Fine needle aspiration cytology of Warthin-like tumor of the thyroid. Acta Cytol; 2007 Jul-Aug;51(4):667-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenolymphoma / pathology. Thyroid Neoplasms / pathology
  • [MeSH-minor] Adult. Biopsy, Fine-Needle. Female. Humans. Oxyphil Cells / pathology. Salivary Gland Neoplasms / pathology

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  • (PMID = 17718150.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Letter
  • [Publication-country] United States
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97. Patnayak R, Jena A, Kumar Chowhan A: Role of cell block preparation in Warthin's tumour. Cytopathology; 2010 Dec;21(6):423; author reply 423
MedlinePlus Health Information. consumer health - Salivary Gland Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenolymphoma / diagnosis. Salivary Gland Neoplasms / diagnosis

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  • [CommentOn] Cytopathology. 2010 Jun;21(3):164-9 [19744189.001]
  • (PMID = 20726866.001).
  • [ISSN] 1365-2303
  • [Journal-full-title] Cytopathology : official journal of the British Society for Clinical Cytology
  • [ISO-abbreviation] Cytopathology
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] England
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98. Stanton DC, Chou JC, Sollecito TP, Stoopler ET, Pringle G, Carrasco LR, deLeeuw K: Recurrent lower lip swelling in a 62-year-old African American female. Cheilitis glandularis. J Oral Maxillofac Surg; 2008 Dec;66(12):2585-91
MedlinePlus Health Information. consumer health - Salivary Gland Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenolymphoma / pathology. Cheilitis / etiology. Lip Neoplasms / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands, Minor / pathology
  • [MeSH-minor] African Americans. Diagnosis, Differential. Female. Humans. Middle Aged. Skin Transplantation

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  • (PMID = 19022139.001).
  • [ISSN] 1531-5053
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Clinical Conference; Journal Article
  • [Publication-country] United States
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