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46. Berrocal Postigo E, Galera Ruiz H, Ruiz Clemente J, González García J, Muñoz Borge F: [Ectopic Warthin's tumour in nasopharynx. Revision of one clinical case]. Acta Otorrinolaringol Esp; 2005 Aug-Sep;56(7):328-30
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  • [Title] [Ectopic Warthin's tumour in nasopharynx. Revision of one clinical case].
  • [Transliterated title] Tumor de warthin ectópico en la nasofaringe. A propósito de un caso clínico.
  • A CT scan is informed as a well delimited and rounded-shaped tumour compatible with lymphoma.
  • Excisional biopsy by a nasal rigid endoscopy is practiced and the histology result is Warthin's tumour.
  • [MeSH-major] Adenolymphoma / pathology. Adenolymphoma / radiography. Choristoma / pathology. Choristoma / radiography. Nasopharyngeal Neoplasms / pathology. Nasopharyngeal Neoplasms / radiography. Nasopharynx

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  • (PMID = 16240924.001).
  • [ISSN] 0001-6519
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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47. Sheahan P, Hafidh M, Toner M, Timon C: Unexpected findings in neck dissection for squamous cell carcinoma: incidence and implications. Head Neck; 2005 Jan;27(1):28-35
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  • These pathologic findings may simulate malignant disease and/or have implications on the already complicated management of patients with head and neck cancer.
  • RESULTS: Ten patients had an unexpected finding.
  • These included metastatic papillary thyroid carcinoma, leukemia, lymphoma, Warthin's tumor, and tuberculosis.
  • [MeSH-minor] Adenolymphoma / pathology. Adenolymphoma / therapy. Aged. Aged, 80 and over. Carcinoma, Papillary / pathology. Carcinoma, Papillary / secondary. Carcinoma, Papillary / surgery. Cricoid Cartilage / pathology. Female. Humans. Leukemia, Lymphocytic, Chronic, B-Cell / pathology. Leukemia, Lymphocytic, Chronic, B-Cell / therapy. Lymphatic Metastasis. Lymphoma, B-Cell / pathology. Lymphoma, B-Cell / therapy. Male. Middle Aged. Retrospective Studies. Thyroid Neoplasms / pathology. Thyroid Neoplasms / secondary. Thyroid Neoplasms / surgery. Thyroidectomy. Tuberculosis, Lymph Node / drug therapy. Tuberculosis, Lymph Node / pathology


48. Giannone N, Lo Muzio L, Politi M: Extracapsular lumpectomy and SMAS flap for benign parotid tumours: an early outcome in a small number of cases on Frey's syndrome and facial nerve dysfunction. J Craniomaxillofac Surg; 2008 Jun;36(4):239-43
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  • None of the patients affected by pleomorphic adenoma or Warthin's tumour had a complete facial palsy.
  • [MeSH-major] Adenolymphoma / surgery. Adenoma, Pleomorphic / surgery. Oral Surgical Procedures / adverse effects. Parotid Neoplasms / surgery. Surgical Flaps

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  • (PMID = 18313936.001).
  • [ISSN] 1010-5182
  • [Journal-full-title] Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
  • [ISO-abbreviation] J Craniomaxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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49. Shaw CK, Sood S, Bradley PJ, Krishnan S: Unusual mass in the parapharyngeal space: a Warthin's tumour. ANZ J Surg; 2006 Mar;76(3):193-4
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  • [Title] Unusual mass in the parapharyngeal space: a Warthin's tumour.
  • Most of the PPS tumours are salivary tumours (pleomorphic adenoma being the most frequent diagnosis), and are thought to originate from minor salivary glands or the deep lobe of the parotid gland.
  • Warthin's tumour, another benign salivary tumour involving the PPS has been rarely reported.
  • A case of bilateral, metachronous Warthin's tumour involving the PPS is reported here.
  • PPS Warthin's tumour is a very rare condition that if undiagnosed may result in considerable morbidity.
  • [MeSH-major] Adenolymphoma / pathology. Neoplasms, Second Primary / pathology. Parotid Neoplasms / pathology. Pharynx / pathology

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  • (PMID = 16626365.001).
  • [ISSN] 1445-1433
  • [Journal-full-title] ANZ journal of surgery
  • [ISO-abbreviation] ANZ J Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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50. Zhang S, Bao R, Bagby J, Abreo F: Fine needle aspiration of salivary glands: 5-year experience from a single academic center. Acta Cytol; 2009 Jul-Aug;53(4):375-82
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  • The only false positive was a pleomorphic adenoma misdiagnosed as adenoid cystic carcinoma.
  • Five benign neoplasms were interpreted as reactive processes, including 2 Warthin's tumors, 2 sebaceous lymphoadenomas and 1 pleomorphic adenoma.

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  • (PMID = 19697720.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
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51. Zhang S, Bao R, Abreo F: Papillary oncocytic cystadenoma of the parotid glands: a report of 2 cases with varied cytologic features. Acta Cytol; 2009 Jul-Aug;53(4):445-8
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  • [Title] Papillary oncocytic cystadenoma of the parotid glands: a report of 2 cases with varied cytologic features.
  • BACKGROUND: Papillary cystadenoma is a rare salivary gland neoplasm, and oncocytic change can be focal or marked.
  • Papillary oncocytic cystadenoma has been reported mainly in the minor salivary glands and occasionally in the parotid glands.
  • Oncocytic neoplasm was diagnosed during intraoperative consultation, and final surgical histology showed a unilocular, cystic, oncocytic neoplasm with variable papillary projections.
  • FNA showed less cellular smears with extensive necrotic debris and a few large sheets of epithelial cells with vague papillary architecture.
  • Oncocytic neoplasm was diagnosed during intraoperative consultation, and final surgical histology showed a unilocular cystic lesion with multiple papillary fronds lined with oncocytic cells and focal metaplastic squamous cells.
  • CONCLUSION: Papillary cystadenoma is rare in the parotid glands, and cytologic features may vary.
  • Warthin's tumor, oncocytoma, intraductal papilloma and acinic cell carcinoma may arise in the differential diagnosis.
  • [MeSH-major] Cystadenoma, Papillary / pathology. Parotid Neoplasms / pathology

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  • (PMID = 19697734.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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52. Righi A, Foschini MP: [Values and limits in fine needle aspiration in the diagnosis of Warthin tumour of the parotid gland]. Pathologica; 2006 Dec;98(6):635-9
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  • [Title] [Values and limits in fine needle aspiration in the diagnosis of Warthin tumour of the parotid gland].
  • [Transliterated title] Valori e limiti dell'agoaspirato nella diagnosi di tumore di Warthin della parotide.
  • Recent paper state that cytological diagnosis of Warthin Tumour of the parotid gland is poorly reproducible and that aspiration procedures damage the tumoral tissue as to make difficult the histological diagnosis.
  • Aim of the present study is to review cytological sampling performed with fine needle sampling without aspiration and to compare them with the relative surgical specimens in order to determine the value of fine needle aspiration in the diagnosis of Warthin Tumour and to quantify' the damage in histological tissue.
  • MATERIALS AND METHOD: All cases with cytological and/or histological diagnosis of Warthin Tumour during the period 1/1/98 to 30/6/04 were retrieved.
  • RESULTS: 38 cases were selected corresponding to 37 patients (1 case of Warthin Tumour bilateral): all tumors were localized in the parotid gland.
  • In all cases the histologic alterations from fine needle were focal, limited to less than 20% of the tumoral area (first category of Batsakis 'classification), and did not prevent the histologic diagnosis of Warthin Tumour.
  • CONCLUSIONS: These data suggest that fine needle aspiration without aspiration is a valuable tool for the per-operative diagnosis of Warthin Tumour.
  • [MeSH-major] Adenolymphoma / pathology. Biopsy, Needle. Parotid Neoplasms / pathology

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  • (PMID = 17285840.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] ita
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Italy
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53. Teymoortash A, Krasnewicz Y, Werner JA: Clinical features of cystadenolymphoma (Warthin's tumor) of the parotid gland: a retrospective comparative study of 96 cases. Oral Oncol; 2006 Jul;42(6):569-73
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  • [Title] Clinical features of cystadenolymphoma (Warthin's tumor) of the parotid gland: a retrospective comparative study of 96 cases.
  • The details of the etiopathogenesis of cystadenolymphoma (Warthin's tumor) are still unclear.
  • To explore the possible risk factors for the development of this tumor, medical records of 81 patients with 96 Warthin's tumors of the parotid glands were compared retrospectively with those of 91 patients with pleomorphic adenoma.
  • The medical history and clinical tumor characteristics of all patients were similar.
  • However, a significant male predominance of patients with Warthin's tumor could be noted (P<0.05).
  • The male to female ratio was 3.3:1 in patients with Warthin's tumor.
  • Multifocal Warthin's tumor were detected in five cases (6.2%), and 10 patients (12.3%) had bilateral lesions.
  • The odds ratio for the incidence of Warthin's tumor among current smokers compared with never smokers was 8.3 (P<0.0001).
  • Compared with never smokers, clearly higher odds of Warthin's tumor was observed in heavy smokers (more than 30 pack-years) (odds ratio=24.1, P<0.0001) than patients who smoked less than 30 pack-years (odds ratio=4.9, P<0.0001).
  • [MeSH-major] Adenolymphoma / etiology. Adenoma, Pleomorphic / etiology. Parotid Neoplasms / etiology

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  • (PMID = 16469528.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
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4. Suwała P, Wilczyński K, Barnaś S, Prudlak E: [A rare case of multiple primary benign neoplasm of parotid gland: oncocytoma and adenolimphoma]. Otolaryngol Pol; 2009 Sep;63(7):89-92
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  • AIM OF THE WORK: The authors present unusually rare case primary multiple synchronicus benign tumor of the ipsilateral parotid gland: oncocytoma and Warthin's tumor, which is rare among occasionally occurred multiple tumors with different histology in the salivary glands.
  • MATERIAL AND METHOD: A 71-year-old man presented with the tumor in the right parotid gland.
  • The preoperative ultrasonography and macroscopic analysis of the removed parotid gland tissue revealed only one tumor recognised histopathologically as adenolimphoma, but upon histopathological examination Warthin's tumor proved to coexist with oncocytoma.
  • RESULTS AND CONCLUSIONS: In the ultrasonography examination some salivary glands tumors may not be recognised.
  • The histopathological examination is the ultimate method in recognising tumors, which are not detected in the preoperative diagnosis.
  • The superficial parotidectomy protects from the recrudescence of the superficial lobe of the parotid gland tumors.
  • The coexistence of the oncocytoma and Warthin's in one parotid gland is extremely rare.
  • [MeSH-major] Adenolymphoma / pathology. Adenoma, Oxyphilic / pathology. Neoplasms, Multiple Primary / pathology. Parotid Neoplasms / pathology

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  • (PMID = 20564910.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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55. Yu H, Liu D, Li C, Huang X, Zhong W: [Clinical application of postauricular muscular fasciae-periosteal flap and modified unwrinkle incision in parotidectomy]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2009 Oct;23(10):1167-9
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  • There were 17 males and 11 females aged 19 to 79 years old (average 50 years old), including 20 cases of mixed tumor, 5 cases of adenolymphoma, 1 case of branchial cleft cyst, 1 case of eosinophilic hyperplastic lymphogranuloma, and 1 case of myoepithelioma.
  • Tumor masses were all prominent, with the diameter of 2.4-3.8 cm and partial-tough texture.
  • The course of disease was 3-18 months (average 9.5 months).
  • Parotid gland and tumor mass were resected with postauricular incision hidden within the hairline, introcession defect (3.0 cm x 2.0 cm x 1.0 cm-3.5 cm x 2.5 cm x 1.5 cm) were repaired with simultaneously adopting postauricular muscular fasciae-periosteal flap (4.0 cm x 3.0 cm x 1.0 cm-5.0 cm x 4.0 cm x 1.5 cm) by turning the pedicle flap 180 degrees.

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  • (PMID = 19957830.001).
  • [ISSN] 1002-1892
  • [Journal-full-title] Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
  • [ISO-abbreviation] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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56. Winnes M, Enlund F, Mark J, Stenman G: The MECT1-MAML2 gene fusion and benign Warthin's tumor: is the MECT1-MAML2 gene fusion specific to mucuepidermoid carcinoma? J Mol Diagn; 2006 Jul;8(3):394-5; author reply 395-6
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  • [Title] The MECT1-MAML2 gene fusion and benign Warthin's tumor: is the MECT1-MAML2 gene fusion specific to mucuepidermoid carcinoma?
  • [MeSH-major] Adenolymphoma / genetics. Carcinoma, Squamous Cell / diagnosis. Carcinoma, Squamous Cell / genetics. Oncogene Proteins, Fusion / genetics
  • [MeSH-minor] Biomarkers, Tumor. Humans. In Situ Hybridization. Sensitivity and Specificity. Translocation, Genetic

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  • (PMID = 16825514.001).
  • [ISSN] 1525-1578
  • [Journal-full-title] The Journal of molecular diagnostics : JMD
  • [ISO-abbreviation] J Mol Diagn
  • [Language] eng
  • [Publication-type] Comment; Letter; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / MECT1-MAML2 fusion protein, human; 0 / Oncogene Proteins, Fusion
  • [Other-IDs] NLM/ PMC1876653
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57. Silva SJ, Costa Junior GT, Brant Filho AC, Faria PR, Loyola AM: Metachronous bilateral pleomorphic adenoma of the parotid gland. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2006 Mar;101(3):333-8
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  • [Title] Metachronous bilateral pleomorphic adenoma of the parotid gland.
  • Bilateral salivary gland tumors are very rare, accounting for 3% of all parotid gland tumors.
  • Although the most common tumor with bilateral development is the Warthin tumor, pleomorphic adenomas (PA) have been diagnosed simultaneously as well, but in a smaller incidence.
  • A total and superficial parotidectomy for left and right tumors, respectively, was performed.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Neoplasms, Multiple Primary / pathology. Parotid Neoplasms / pathology

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  • (PMID = 16504867.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 51
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58. Basu S, Houseni M, Alavi A: Significance of incidental fluorodeoxyglucose uptake in the parotid glands and its impact on patient management. Nucl Med Commun; 2008 Apr;29(4):367-73
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  • In addition, we also examined patients in whom there was no documented evidence of parotid pathology before FDG-PET scan and a suspicion of disease involvement was first raised in the reports in view of focal uptake in the FDG-PET images.
  • Only those cases with no earlier history of disease involvement of parotid gland or known parotid pathology before FDG-PET were selected for this analysis.
  • These patients were selected from a population of patients with a known malignancy elsewhere who underwent conventional whole-body FDG-PET or PET/CT for staging, disease viability assessment, or treatment monitoring purposes and had demonstrated varying patterns of FDG uptake (unilateral, bilateral, symmetric, or asymmetric) in the parotid glands.
  • In five patients with asymmetric and focally enhanced FDG uptake, a suspicion of disease involvement was raised in the reports.
  • No revelation of disease either by the MRI or follow-up clinical and FDG-PET examinations was observed in patients with asymmetric diffuse uptake.
  • The final diagnosis based upon histopathology revealed primary parotid tumors (e.g., Warthin's tumor and pleomorphic adenoma, which presented as FDG-avid parotid incidentaloma) or metastatic disease involvement.
  • An asymmetrical uptake, especially when focal, would warrant further radiological and histopathological correlation to rule out disease involvement.
  • At times, this can lead to the detection of an asymptomatic hitherto unknown etiology, which would have been otherwise interpreted as a metastatic disease in the background of an existing malignancy in these patients; this is noteworthy as it may have a bearing on the subsequent management of these patients.

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  • (PMID = 18317302.001).
  • [ISSN] 0143-3636
  • [Journal-full-title] Nuclear medicine communications
  • [ISO-abbreviation] Nucl Med Commun
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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59. Mortensen KS, Hjortlund J, Bjørndal K, Krogdal A, Godballe C: [Salivary gland tumors in the County of Funen, 1984-2003]. Ugeskr Laeger; 2008 Feb 11;170(7):545-8
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  • [Title] [Salivary gland tumors in the County of Funen, 1984-2003].
  • INTRODUCTION: The objective of this study is to estimate the incidence of major salivary gland tumors in a geographically well-defined area (the County of Funen, Denmark) and to analyse the demographic data and distribution of histological types.
  • MATERIALS AND METHODS: Patients with salivary gland tumors were identified through a search on pathology and diagnosis codes in the period 1984-2003, which initially resulted in a group of 951 patients.
  • RESULTS: The incidence of major salivary gland tumors for the County of Funen is calculated to 7.3 per 100,000 residents per year.
  • Pleomorphic adenoma (55%) was the most common type, followed by adenolymphoma (29%).
  • 90% of the tumors were found in the parotid gland - 93% benign and 7% malignant.
  • The occurrence of pleomorphic adenomas among females (66%) was higher than among males (43%), on the other hand more adenolymphomas were found in males (43%) than in females (17%).
  • CONCLUSION: The incidence of major salivary gland tumors in the County of Funen is calculated to 7.3 per 100,000 inhabitants per year which is equivalent to 383 new cases in Denmark per year.
  • [MeSH-major] Adenolymphoma / epidemiology. Adenoma, Pleomorphic / epidemiology. Salivary Gland Neoplasms / epidemiology

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  • (PMID = 18291086.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Denmark
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60. Uğuz MZ, Onal HK, Eroğlu OO, Etit D: [Sensitivity and specificity of fine needle aspiration biopsy in parotid masses]. Kulak Burun Bogaz Ihtis Derg; 2007;17(2):96-9
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  • The most common histopathological diagnosis was pleomorphic adenoma (n=7, 24.1%), followed by mucoepidermoid carcinoma (n=4, 13.8%), and Warthin's tumor (n=3, 10.3%).
  • [MeSH-minor] Adenolymphoma / diagnosis. Adenolymphoma / pathology. Adenoma, Pleomorphic / diagnosis. Adenoma, Pleomorphic / pathology. Adult. Aged. Aged, 80 and over. Carcinoma, Mucoepidermoid / diagnosis. Carcinoma, Mucoepidermoid / pathology. Female. Humans. Male. Middle Aged. Predictive Value of Tests. Sensitivity and Specificity

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  • (PMID = 17527061.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] tur
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] Turkey
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61. Pescarmona E, Perez M, Faraggiana T, Granati L, Baroni CD: Nodal peripheral T-cell lymphoma associated with Warthin's tumour. Histopathology; 2005 Aug;47(2):221-2
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  • [Title] Nodal peripheral T-cell lymphoma associated with Warthin's tumour.
  • [MeSH-major] Adenolymphoma / pathology. Lymphoma, T-Cell, Peripheral / pathology

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  • (PMID = 16045788.001).
  • [ISSN] 0309-0167
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD20; 0 / Antigens, CD3; 0 / Antigens, CD30; 0 / Antigens, CD43; 0 / Antigens, CD79; 0 / CD79A protein, human; 0 / Receptors, Antigen, B-Cell; 0 / Sialoglycoproteins; 0 / UN1 sialoglycoprotein, human
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62. Lee YY, Wong KT, King AD, Ahuja AT: Imaging of salivary gland tumours. Eur J Radiol; 2008 Jun;66(3):419-36
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  • Salivary gland neoplasms account for <3% of all tumors.
  • As a general rule, the smaller the involved salivary gland, the higher is the possibility of the tumor being malignant.
  • The role of imaging in assessment of salivary gland tumour is to define intra-glandular vs. extra-glandular location, detect malignant features, assess local extension and invasion, detect nodal metastases and systemic involvement.
  • If deep tissue extension is suspected or malignancy confirmed on cytology, an MRI or CT is mandatory to evaluate tumour extent, local invasion and perineural spread.
  • Recent study suggests that MR spectroscopy may differentiate malignant and benign salivary gland tumours as well as distinguishing Warthin's tumor from pleomorphic adenoma.
  • Sialography is used to delineate the salivary ductal system and has limited role in assessment of tumour extent.

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  • (PMID = 18337041.001).
  • [ISSN] 0720-048X
  • [Journal-full-title] European journal of radiology
  • [ISO-abbreviation] Eur J Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Contrast Media
  • [Number-of-references] 44
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63. Yaor MA: The pattern of presentation of salivary gland tumors in Africa: A review of published reports. Ear Nose Throat J; 2010 Feb;89(2):E17-21
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  • [Title] The pattern of presentation of salivary gland tumors in Africa: A review of published reports.
  • Salivary glands are the site of a wide variety of histopathologic types of benign and malignant tumors.
  • The author reviewed 23 articles from 12 African countries published between 1980 and 2004 to examine patterns of salivary gland tumors.
  • Also, there may be a female preponderance in Africa, and Warthin tumor is rare.
  • [MeSH-major] Adenoma, Pleomorphic / epidemiology. Adenoma, Pleomorphic / pathology. Carcinoma, Adenoid Cystic / epidemiology. Carcinoma, Adenoid Cystic / pathology. Salivary Gland Neoplasms / epidemiology. Salivary Gland Neoplasms / pathology

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  • (PMID = 20155665.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 23
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64. Ellis GL: Lymphoid lesions of salivary glands: malignant and benign. Med Oral Patol Oral Cir Bucal; 2007 Dec;12(7):E479-85
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  • Lymphoepithelial sialadenitis, HIV-associated salivary gland disease, chronic sclerosing sialadenitis, Warthin tumor, and extranodal marginal zone B-cell lymphoma are examples of this pathology that are sometimes problematic to differentiate from one another.
  • [MeSH-minor] Adenolymphoma / diagnosis. Carcinoma / diagnosis. Humans. Lymphoma, B-Cell, Marginal Zone / diagnosis. Prognosis. Sialadenitis / diagnosis

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  • (PMID = 17978770.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 30
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65. Jung SM, Hao SP: Warthin's tumor with multiple granulomas: a clinicopathologic study of six cases. Diagn Cytopathol; 2006 Aug;34(8):564-7
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  • [Title] Warthin's tumor with multiple granulomas: a clinicopathologic study of six cases.
  • Granulomatous inflammation occurring in Warthin's tumor is a rare phenomenon.
  • We studied cases of Warthin's tumor with granulomatous inflammation to analyze the possible relationship with prior FNA.
  • Granulomatous inflammation was noted in 6 cases (1.6%) of 382 cases of Warthin's tumor in a medical center.
  • All 6 cases showed typical features of Warthin's tumor accompanied by multiple granulomas.
  • There were 2 cases with history of preoperative FNA; both already had granulomas in Warthin's tumor in cytologic specimens taken by aspiration.
  • The pathogenesis of granulomatous inflammation in Warthin's tumor remains speculative.
  • [MeSH-major] Adenolymphoma / etiology. Adenolymphoma / pathology. Granuloma / etiology. Parotid Neoplasms / etiology

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  • [Copyright] (c) 2006 Wiley-Liss, Inc.
  • (PMID = 16850483.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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66. Ishibashi M, Fujii S, Kawamoto K, Nishihara K, Matsusue E, Kodani K, Kaminou T, Ogawa T: Capsule of parotid gland tumor: evaluation by 3.0 T magnetic resonance imaging using surface coils. Acta Radiol; 2010 Dec;51(10):1103-10
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  • [Title] Capsule of parotid gland tumor: evaluation by 3.0 T magnetic resonance imaging using surface coils.
  • BACKGROUND: magnetic resonance (MR) imaging of parotid gland tumors has been widely reported, although few reports have evaluated the capsule of parotid gland tumors in detail.
  • PURPOSE: to evaluate the diagnostic usefulness of 3.0 T MR imaging with surface coils for detection of the parotid gland tumor capsule, and to clarify the characteristics of the capsules.
  • MATERIAL AND METHODS: seventy-eight patients with parotid gland tumors (63 benign and 15 malignant) were evaluated.
  • It was retrospectively assessed whether each parotid gland tumor was completely surrounded by a capsule.
  • Visual interpretations were compared with histopathological findings to evaluate the diagnostic ability of MR imaging to detect parotid gland tumor capsules.
  • Statistical evaluation was conducted concerning the presence of capsules, capsular irregularity, and the difference in contrast enhancement between benign and malignant tumors, and that between pleomorphic adenomas and Warthin's tumors.
  • RESULTS: capsules completely surrounding the tumor on MR imaging yielded a sensitivity of 87.7% (50/57), specificity of 90.5% (19/21), and accuracy of 88.5% (69/78).
  • Benign tumors had a capsule completely surrounding the tumor significantly more often than malignant tumors (P = 0.009).
  • Concerning capsular irregularity, malignant tumors tended to have more irregular capsules than benign tumors, although there were no significant differences.
  • The capsules of malignant tumors enhanced significantly more strongly than those of benign tumors (P = 0.018).
  • CONCLUSION: 3.0 T MR imaging using surface coils could correctly depict parotid gland tumor capsules in most cases.
  • Most benign and some malignant tumors had capsules completely surrounding the tumors.
  • Malignancy should be considered in tumors with irregular and strongly enhancing capsules.
  • [MeSH-major] Adenolymphoma / diagnosis. Adenoma, Pleomorphic / diagnosis. Carcinoma, Adenoid Cystic / diagnosis. Magnetic Resonance Imaging / methods. Parotid Neoplasms / diagnosis

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  • (PMID = 20883183.001).
  • [ISSN] 1600-0455
  • [Journal-full-title] Acta radiologica (Stockholm, Sweden : 1987)
  • [ISO-abbreviation] Acta Radiol
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Heterocyclic Compounds; 0 / Organometallic Compounds; 0199MV609F / gadoteridol; AU0V1LM3JT / Gadolinium
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67. Heeremans EH, Mastboom WJ: [Subtotal parotidectomy for a parotid gland tumour in two players of wind instruments, with preservation of facial nerve function]. Ned Tijdschr Geneeskd; 2007 Mar 3;151(9):543-7
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  • [Title] [Subtotal parotidectomy for a parotid gland tumour in two players of wind instruments, with preservation of facial nerve function].
  • [Transliterated title] Subtotale parotidectomie wegens een parotistumor bij twee blaasmuzikanten, met behoud van de N.-facialisfuncties.
  • Two professional musicians, a 55-year-old clarinet player and a 58-year-old trumpet player, presented to the surgical outpatient clinic with a Warthin's tumour and a pleomorphic adenoma in the deep lobe of the parotid gland, respectively.
  • [MeSH-major] Adenolymphoma / surgery. Adenoma, Pleomorphic / surgery. Facial Nerve / physiology. Parotid Neoplasms / surgery

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  • (PMID = 17373397.001).
  • [ISSN] 0028-2162
  • [Journal-full-title] Nederlands tijdschrift voor geneeskunde
  • [ISO-abbreviation] Ned Tijdschr Geneeskd
  • [Language] dut
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Netherlands
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68. Fulciniti F, Losito NS, Ionna F, Longo F, Aversa C, Botti G, Foschini MP: Sclerosing polycystic adenosis of the parotid gland: report of one case diagnosed by fine-needle cytology with in situ malignant transformation. Diagn Cytopathol; 2010 May;38(5):368-73
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  • In line with numerous other pathological analogies between breast and salivary gland lesions, SPA shares with fibrocystic disease of the breast many histopathological features, i.e., fibrosis, oncocytic (apocrine) changes, hyperplasia of ductal and acinar epithelium, cystic dilation of ducts, and, often, atypical epithelial changes.
  • The spectrum of pathological lesions entering differential diagnosis comprised sebaceous adenoma, Warthin's tumors with presence of sebaceous remnants, and low-grade mucoepidermoid carcinoma.

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  • (PMID = 19937766.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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69. Hatch RL, Shah S: Warthin tumor: a common, benign tumor presenting as a highly suspicious mass. J Am Board Fam Pract; 2005 Jul-Aug;18(4):320-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Warthin tumor: a common, benign tumor presenting as a highly suspicious mass.

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  • (PMID = 15994480.001).
  • [ISSN] 0893-8652
  • [Journal-full-title] The Journal of the American Board of Family Practice
  • [ISO-abbreviation] J Am Board Fam Pract
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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70. Tokyol C, Dilek FH, Aktepe F, Ayçiçek A, Altuntaş A: Oncocytic lipoadenoma of the parotid gland: a case report with fine needle aspiration cytology findings. Kulak Burun Bogaz Ihtis Derg; 2010 May-Jun;20(3):146-9
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  • Oncocytic lipoadenoma of the salivary gland is a rarely encountered tumor.
  • Fine-needle aspiration yielded oncocytic cells exclusively, suggesting Warthin tumor or an oncocytoma.
  • Oncocytic lipoadenoma should be considered in the differential diagnosis of oncocytic proliferations and oncocytic tumors in the parotid gland.
  • [MeSH-major] Adenoma / pathology. Adenoma, Oxyphilic / pathology. Parotid Neoplasms / pathology
  • [MeSH-minor] Adenolymphoma / pathology. Adenolymphoma / surgery. Biopsy, Fine-Needle. Humans. Male. Middle Aged. Parotid Gland / surgery. Treatment Outcome

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  • (PMID = 20465541.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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71. Gallego L, Junquera L, Villarreal P, Villalaín L: Familial Warthin tumor: occurrence in monozygotic twins. J Oral Maxillofac Surg; 2010 Jun;68(6):1400-1
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  • [Title] Familial Warthin tumor: occurrence in monozygotic twins.
  • [MeSH-major] Adenolymphoma / congenital. Adenolymphoma / genetics. Diseases in Twins / congenital. Parotid Neoplasms / congenital. Parotid Neoplasms / genetics

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  • (PMID = 19944513.001).
  • [ISSN] 1531-5053
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Twin Study
  • [Publication-country] United States
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72. Pastore A, Carinci F, Pelucchi S: Genetic expression profiling of parotid neoplasms by cDNA microarrays. Acta Otorhinolaryngol Ital; 2005 Jun;25(3):153-60
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  • Samples were derived from 5 patients with pleomorphic adenoma, 4 with Warthin's tumour, one with clear cell carcinoma, and 2 with mucoepidermoid carcinoma.
  • Benign Warthin's tumour and pleomorphic adenoma showed very distinctive gene expression patterns.
  • A total of 133 genes differentiated the single malignant clear cell carcinoma from non-tumour salivary glands (p < 0.01), whereas only 16 genes separated it from the highly related benign pleomorphic adenoma (p < 0.01).
  • The results show gene expression alterations common to all tumours and unique to each benign and malignant tumour.
  • The numerous Expressed Sequence Tags of unknown function we identified could also become useful as tumour markers and represent a set of novel tumour-associated genes.

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  • (PMID = 16450770.001).
  • [ISSN] 0392-100X
  • [Journal-full-title] Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale
  • [ISO-abbreviation] Acta Otorhinolaryngol Ital
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2639868
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73. Taylor TR, Cozens NJ, Robinson I: Warthin's tumour: a retrospective case series. Br J Radiol; 2009 Nov;82(983):916-9
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  • [Title] Warthin's tumour: a retrospective case series.
  • Warthin's tumour (benign cystadenolymphoma) is the second most common salivary gland tumour after pleomorphic salivary adenoma, and it is commonly encountered in routine head and neck ultrasonography.
  • We describe 7 cases of radiologically infarcting Warthin's tumours in situ in a retrospective analysis of 76 patients, and demonstrate an approximate incidence of at least 9% of infarction following fine-needle aspiration in lesions left in situ.
  • [MeSH-major] Adenolymphoma / pathology. Parotid Gland / pathology. Parotid Neoplasms / pathology

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  • (PMID = 19433486.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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74. Faur A, Lazăr E, Cornianu M, Dema A, Vidita CG, Găluşcan A: Warthin tumor: a curious entity--case reports and review of literature. Rom J Morphol Embryol; 2009;50(2):269-73
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  • [Title] Warthin tumor: a curious entity--case reports and review of literature.
  • Warthin tumor was first described in the American literature, by Aldred Warthin, in 1929, the pathologist who named this tumor papillary cystadenoma lymphomatosum, but since than it was also knew as adenolymphoma, cystadenolymphoma, and Warthin tumor.
  • Because of its microscopically appearance and unknown origin, this tumor entity is still fascinating head and neck surgeons and pathologist.
  • We evaluate the histopathological aspect of Warthin tumors using Hematoxylin-Eosin stain, and immunohistochemical and histological techniques.
  • We reviewed the medical record of patients with salivary gland tumors diagnosed at County Hospital of Timisoara from 2002-2008.
  • In six years, 22 cases with Warthin tumor were diagnosed and among them 17 men and five women, with average age 58.47.
  • The analysis showed that 77.27% of Warthin tumors occurred in men, and the main histopathological aspect was with 50% epithelial component.
  • The standard and the histological and immunohistochemical techniques highlighted the complex and variable microscopical appearance of Warthin tumor that the pathologist should consider when a diagnosis for this tumor is to be considered.
  • [MeSH-major] Adenolymphoma / pathology. Salivary Gland Neoplasms / pathology

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  • (PMID = 19434322.001).
  • [ISSN] 1220-0522
  • [Journal-full-title] Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
  • [ISO-abbreviation] Rom J Morphol Embryol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Romania
  • [Chemical-registry-number] 0 / Antigens, CD20; 0 / Mucins
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75. Daneshbod Y, Daneshbod K, Khademi B: Diagnostic difficulties in the interpretation of fine needle aspirate samples in salivary lesions: diagnostic pitfalls revisited. Acta Cytol; 2009 Jan-Feb;53(1):53-70
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  • Benign cases with false positive diagnosis were Warthin tumor and pleomorphic adenoma.
  • Several clinically important pitfalls with nonsalivary tumors of jaw and skin are demonstrated in our series.

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  • (PMID = 19248555.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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76. Linecker A, Kermer C, Sulzbacher I, Angelberger P, Kletter K, Dudczak R, Ewers R, Becherer A: Uptake of (18)F-FLT and (18)F-FDG in primary head and neck cancer correlates with survival. Nuklearmedizin; 2008;47(2):80-5; quiz N12
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  • Tumour tracer uptake was determined by standardized uptake value (SUV) normalized to body weight and /non-tumor ratios (T/N). (18)F-FDG and (18)F-FLT uptake were compared with histopathologic and immunohistochemical results.
  • RESULTS: 19 patients had malignant tumours; one patient had a benign cystadenoma (so called Warthin's tumour) of the parotid gland.
  • One negative lesion turned out to be a malignant T1 stage squamous cell carcinoma in both PET scans, the Warthin's tumour was false positive with (18)F-FDG but showed only faint uptake with (18)F-FLT, resulting in a sensitivity of 95 % for both tracers.

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  • (PMID = 18392317.001).
  • [ISSN] 0029-5566
  • [Journal-full-title] Nuklearmedizin. Nuclear medicine
  • [ISO-abbreviation] Nuklearmedizin
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Dideoxynucleosides; 0 / Fluorine Radioisotopes; 0 / Radioisotopes; 0Z5B2CJX4D / Fluorodeoxyglucose F18; PG53R0DWDQ / alovudine
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77. Tanaka S, Tabuchi K, Oikawa K, Kohanawa R, Okubo H, Ikebe D, Noguchi M, Hara A: Synchronous unilateral parotid gland neoplasms of three different histological types. Auris Nasus Larynx; 2007 Jun;34(2):263-6
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  • A 67-year-old male with three synchronous tumors in the unilateral parotid gland is reported.
  • Postoperative histological examinations confirmed the presence of three synchronous primary tumors, specifically pleomorphic adenoma, Warthin's tumor and salivary duct carcinoma, in the right parotid gland.
  • [MeSH-major] Adenolymphoma / pathology. Adenoma, Pleomorphic / pathology. Carcinoma / pathology. Neoplasms, Multiple Primary / pathology. Parotid Neoplasms / pathology. Salivary Ducts / pathology

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  • (PMID = 16938417.001).
  • [ISSN] 0385-8146
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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78. Ozawa N, Okamura T, Koyama K, Nakayama K, Kawabe J, Shiomi S, Yamane H, Inoue Y: Retrospective review: usefulness of a number of imaging modalities including CT, MRI, technetium-99m pertechnetate scintigraphy, gallium-67 scintigraphy and F-18-FDG PET in the differentiation of benign from malignant parotid masses. Radiat Med; 2006 Jan;24(1):41-9
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  • RESULTS: All of the benign tumors had smooth margins on CT and MRI.
  • All Warthin's tumors showed high technetium accumulation.
  • Many of malignant tumors showed high FDG accumulation.
  • Both pleomorphic adenomas and Warthin's tumors showed high accumulation in some cases on 18F-FDG PET.
  • Among 15 patients with pleomorphic adenoma, 14 patients showed marked hyperintensity relative to CSF on T2-weighted images and partial enhancement on contrast-enhanced T1-weighted images.

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  • (PMID = 16715661.001).
  • [ISSN] 0288-2043
  • [Journal-full-title] Radiation medicine
  • [ISO-abbreviation] Radiat Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Gallium Radioisotopes; 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18; A0730CX801 / Sodium Pertechnetate Tc 99m
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79. Krishnanand G, Kaur M, Rao RV, Monappa V: Oncocytic variant of mucoepidermoid carcinoma of submandibular gland: an unusual clinical and morphological entity. Indian J Pathol Microbiol; 2007 Jul;50(3):538-40
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  • In this case report we describe a rare tumor--Oncocytic variant of Mucoepidermoid carcinoma of the submandibular salivary gland with a review of the literature.
  • Oncocytic metaplasia in salivary glands is a benign change that is associated with increasing age and also seen in a few salivary gland neoplasms', which include oncocytoma, Warthin's tumor, and the rare, oncocytic carcinoma.

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  • (PMID = 17883126.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] India
  • [Number-of-references] 10
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80. Barabás J, Bogdán S, Suba Z, Szabó G, Lukáts O, Decker I, Huszár T: [Parotid gland Warthin's tumor combined with actinomycosis]. Orv Hetil; 2006 Apr 30;147(17):807-10
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  • [Title] [Parotid gland Warthin's tumor combined with actinomycosis].
  • [Transliterated title] Actinomycosissal kombinált, parotisban elhelyezkedo Warthin-tumor ritka esete.
  • The authors describe the diagnostic problems and difficulties of treatment of Warthin's tumor combined with actinomycosis.
  • The final histological evaluation was Warthin's tumor with actinomycosis.
  • Eight years after treatment the patient is free of disease.
  • [MeSH-major] Actinomycosis. Adenolymphoma. Parotid Neoplasms

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  • (PMID = 16780189.001).
  • [ISSN] 0030-6002
  • [Journal-full-title] Orvosi hetilap
  • [ISO-abbreviation] Orv Hetil
  • [Language] hun
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Hungary
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; 74469-00-4 / Amoxicillin-Potassium Clavulanate Combination
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81. Teymoortash A, Schrader C, Shimoda H, Kato S, Werner JA: Evidence of lymphangiogenesis in Warthin's tumor of the parotid gland. Oral Oncol; 2007 Jul;43(6):614-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Evidence of lymphangiogenesis in Warthin's tumor of the parotid gland.
  • The details of the pathogenesis of cystadenolymphoma (Warthin's tumor) of the parotid gland are still unclear.
  • Neovascularization is considered to be a pivotal factor for solid tumor progression and biological behavior of the tumor.
  • Using double-labeling immunohistochemistry for LYVE-1 and CD34 (specific markers for lymphatic and vascular endothelial cells, respectively) this study analyzes lymphatic vessel density (LVD) and blood vessel density (BVD) in 10 Warthin's tumors and 10 pleomorphic adenomas of the parotid gland as well as in 5 normal parotid glands and 5 normal parotid lymph nodes.
  • There was no significant difference in the intratumoral LVD and BVD among pleomorphic adenoma and normal parotid gland tissue.
  • In contrast, the intratumoral LVD and BVD were significantly higher in Warthin's tumor than pleomorphic adenoma, normal parotid gland and parotid lymph node (P<0.0001 versus P<0.004).
  • The increase in lymphatic vessels in Warthin's tumor suggests that epithelial tumor cells might promote lymphangiogenesis in this kind of lesions.
  • [MeSH-major] Adenolymphoma / pathology. Lymphangiogenesis. Parotid Neoplasms / pathology
  • [MeSH-minor] Adenoma, Pleomorphic / blood supply. Adenoma, Pleomorphic / pathology. Antigens, CD34 / metabolism. Endothelial Cells / metabolism. Female. Humans. Immunohistochemistry. Lymph Nodes / blood supply. Male. Middle Aged. Neovascularization, Pathologic / metabolism. Neovascularization, Pathologic / pathology. Vesicular Transport Proteins / metabolism

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  • (PMID = 16996778.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / LYVE1 protein, human; 0 / Vesicular Transport Proteins
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82. Grosheva M, Ortmann M, Beutner D: [Facial nerve palsy due to a benign parotid gland tumor]. HNO; 2010 Dec;58(12):1197-8, 1200
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  • [Title] [Facial nerve palsy due to a benign parotid gland tumor].
  • Histological work-up yielded a diagnosis of Warthin's tumor with necrotic changes.
  • [MeSH-major] Adenolymphoma / complications. Facial Paralysis / complications. Parotid Neoplasms / complications

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  • [Cites] Arch Otolaryngol Head Neck Surg. 2000 Apr;126(4):506-10 [10772305.001]
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  • (PMID = 20607202.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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83. Alibek S, Zenk J, Bozzato A, Lell M, Grunewald M, Anders K, Rabe C, Iro H, Bautz W, Greess H: The value of dynamic MRI studies in parotid tumors. Acad Radiol; 2007 Jun;14(6):701-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The value of dynamic MRI studies in parotid tumors.
  • RATIONALE AND OBJECTIVES: To evaluate the ability of dynamic contrast-enhanced magnetic resonance imaging (MRI) to differentiate several tumor entities of the parotid gland in a prospective clinical trial.
  • MATERIALS AND METHODS: A total of 112 patients with parotid tumors were examined with dynamic contrast-enhanced 1.5 T MRI.
  • Signal intensity versus time (SIvT) curves was obtained for all tumors.
  • Finally, all MRIs together with the tumor specific SIvT curves were re-read and correlated with histopathologic diagnosis.
  • RESULTS: Four characteristic intensity-time curves were observed: pleomorphic adenoma showed a gradual increase in signal intensity, followed by a plateau phase on a low intensity level.
  • Adenolymphomas as well as carcinomas showed a rapid increase in signal intensity followed by a plateau phase.
  • Statistic significance was found for the time-to-peak values for adenolymphomas and pleomorphic adenomas and for the maximum peak signal intensity values for carcinomas.
  • Together with other morphologic MRI criteria (contrast enhancement, border characteristics) and clinical features, a differentiation between adenolymphoma and carcinoma was possible.
  • CONCLUSIONS: With additional dynamic contrast-enhanced MRI, a more reliable differentiation between common parotid tumors is possible before surgery.
  • [MeSH-major] Adenolymphoma / diagnosis. Adenoma, Pleomorphic / diagnosis. Carcinoma / diagnosis. Magnetic Resonance Imaging / methods. Parotid Gland / pathology. Parotid Neoplasms / diagnosis

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  • (PMID = 17502260.001).
  • [ISSN] 1076-6332
  • [Journal-full-title] Academic radiology
  • [ISO-abbreviation] Acad Radiol
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; AU0V1LM3JT / Gadolinium
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84. Gürbüz Y, Yildiz K, Aydin O, Almaç A: Immunophenotypical profiles of salivary gland tumours: a new evidence for their histogenetic origin. Pathologica; 2006 Apr;98(2):147-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • 30 cases of salivary gland tumours (18 pleomorphic adenomas, 8 Warthin's tumours, 2 basal cell adenomas, 2 acinic cell carcinomas) were included in our study.
  • SMA was not detected in Warthin's tumour (p < 0.0001).
  • CK10 immunoreactivity was observed in 5 Warthin's tumour.
  • Immunophenotypic profile of Warthin's tumour is suggestive of an embryological remnant origin.
  • [MeSH-minor] Adenolymphoma / chemistry. Adenolymphoma / pathology. Adenoma / chemistry. Adenoma / pathology. Adenoma, Pleomorphic / chemistry. Adenoma, Pleomorphic / pathology. Carcinoma, Acinar Cell / chemistry. Carcinoma, Acinar Cell / pathology. Humans. Immunophenotyping. Organ Specificity. Protein Isoforms / analysis. Retrospective Studies

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  • (PMID = 16929788.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Actins; 0 / Neoplasm Proteins; 0 / Protein Isoforms; 68238-35-7 / Keratins
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85. Leibowitz JM, Montone KT, Basu D: Warthin tumor presenting as a fungal abscess in an immunocompetent host: case report and review of the literature. Head Neck; 2010 Jan;32(1):133-6
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  • [Title] Warthin tumor presenting as a fungal abscess in an immunocompetent host: case report and review of the literature.
  • Definitive excision ultimately demonstrated Candida glabrata infecting a Warthin tumor.
  • The case also expands the spectrum of disease associated with C. glabrata.
  • Warthin tumor may be an occult etiology for a parotid fungal abscess, and definitive diagnosis and therapy may require parotidectomy.
  • [MeSH-major] Abscess / surgery. Adenolymphoma / surgery. Candida glabrata. Candidiasis / surgery. Immunocompetence. Parotid Neoplasms / surgery

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  • (PMID = 19340859.001).
  • [ISSN] 1097-0347
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 15
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86. Veder LL, Kerrebijn JD, Smedts FM, den Bakker MA: Diagnostic accuracy of fine-needle aspiration cytology in Warthin tumors. Head Neck; 2010 Dec;32(12):1635-40
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  • [Title] Diagnostic accuracy of fine-needle aspiration cytology in Warthin tumors.
  • BACKGROUND: Our aim was to evaluate the diagnostic accuracy of fine-needle aspiration cytology (FNAC) for Warthin tumors of the parotid gland.
  • METHODS: All cytologic diagnoses of Warthin tumor between 1990 and 2007 were correlated with available histology.
  • RESULTS: In 310 cases, Warthin tumor was diagnosed by FNAC.
  • In 127 of these 133 cases (95.5%), the diagnosis Warthin tumor was confirmed by histology.
  • CONCLUSION: The diagnostic accuracy of FNAC for the diagnosis of Warthin tumor is high and the percentage of missed malignant tumors is very low.
  • Our results imply that a cytologic diagnosis of Warthin tumor may justify conservative treatment.
  • [MeSH-major] Adenolymphoma / diagnosis. Biopsy, Fine-Needle. Parotid Neoplasms / diagnosis


87. Foschini MP, Gaiba A, Cocchi R, Pennesi MG, Pession A: p63 expression in salivary gland tumors: role of DeltaNp73L in neoplastic transformation. Int J Surg Pathol; 2005 Oct;13(4):329-35
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] p63 expression in salivary gland tumors: role of DeltaNp73L in neoplastic transformation.
  • To illustrate the role of p63 and its truncated variants in salivary gland tumors, 23 consecutive tumors and 6 normal salivary glands were studied immunohistochemically with anti-p63 antibody and by reverse transcriptase (RT) and nested polymerase chain reaction (PCR) to detect p63 isoform expression.
  • Tumors: p63 antibody was positive in the following: Warthin tumor (WT) (3/3), oncocytoma (OC) (1/1), pleomorphic adenoma (PA) (7/7), polymorphous-low-grade adenocarcinoma (PLGA) (3/3), adenoid-cystic carcinoma (ADCC)(3/4), epithelial-myoepithelial-cell carcinoma (EMC) (1/1), and myoepithelial-cell carcinoma (MCC) (1/1).
  • By RT and nested PCR all tumors expressed p63 irrespective of their morphologic differentiation.
  • [MeSH-minor] Adenocarcinoma / metabolism. Adenocarcinoma / pathology. Adenolymphoma / metabolism. Adenolymphoma / pathology. Adenoma, Oxyphilic / metabolism. Adenoma, Oxyphilic / pathology. Adenoma, Pleomorphic / metabolism. Adenoma, Pleomorphic / pathology. Adult. Aged. Carcinoma, Adenoid Cystic / metabolism. Carcinoma, Adenoid Cystic / pathology. Cell Proliferation. DNA-Binding Proteins. Exons. Female. Gene Expression Regulation, Neoplastic. Genes, Tumor Suppressor. Humans. Immunohistochemistry. Male. Middle Aged. Myoepithelioma / metabolism. Myoepithelioma / pathology. Polymerase Chain Reaction. Protein Isoforms. Reverse Transcriptase Polymerase Chain Reaction. Salivary Glands / cytology. Salivary Glands / metabolism. Salivary Glands / pathology. Transcription Factors. Tumor Suppressor Proteins

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  • (PMID = 16273188.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA-Binding Proteins; 0 / Phosphoproteins; 0 / Protein Isoforms; 0 / TP63 protein, human; 0 / Trans-Activators; 0 / Transcription Factors; 0 / Tumor Suppressor Proteins
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88. Ito FA, Ito K, Coletta RD, Vargas PA, Lopes MA: Immunohistochemical study of androgen, estrogen and progesterone receptors in salivary gland tumors. Braz Oral Res; 2009 Oct-Dec;23(4):393-8
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  • [Title] Immunohistochemical study of androgen, estrogen and progesterone receptors in salivary gland tumors.
  • The aim of this work was to study the immunohistochemical expression of androgen receptor, estrogen receptor and progesterone receptor in pleomorphic adenomas, Warthin's tumors, mucoepidermoid carcinomas and adenoid cystic carcinomas of salivary glands.
  • A total of 41 pleomorphic adenomas, 30 Warthin's tumors, 30 mucoepidermoid carcinomas and 30 adenoid cystic carcinomas were analyzed, and the immunohistochemical expression of these hormone receptors were assessed.
  • Androgen receptor was positive in 2 cases each of pleomorphic adenoma, mucoepidermoid carcinoma and adenoid cystic carcinoma.
  • In conclusion, the results do not support a role of estrogen and progesterone in the tumorigenesis of pleomorphic adenomas, Warthin's tumors, mucoepidermoid carcinomas and adenoid cystic carcinomas.
  • However, androgen receptors can play a role in a small set of salivary gland tumors, and this would deserve further studies.

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  • (PMID = 20027446.001).
  • [ISSN] 1807-3107
  • [Journal-full-title] Brazilian oral research
  • [ISO-abbreviation] Braz Oral Res
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Brazil
  • [Chemical-registry-number] 0 / Receptors, Androgen; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
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89. de Oliveira FA, Duarte EC, Taveira CT, Máximo AA, de Aquino EC, Alencar Rde C, Vencio EF: Salivary gland tumor: a review of 599 cases in a Brazilian population. Head Neck Pathol; 2009 Dec;3(4):271-5
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  • [Title] Salivary gland tumor: a review of 599 cases in a Brazilian population.
  • Salivary gland tumors consist of a group of heterogeneous lesions with complex clinicopathological characteristics and distinct biological behaviors.
  • Worldwide series show a contrast in the relative incidence of salivary gland tumors, with some discrepancies in clinicopathological data.
  • Benign tumors represented 78.3% of the cases.
  • Parotid gland tumors were the most frequent (68.5% of cases) and patient age ranged from 1 to 88 years-old (median of 45 years old).
  • The most frequent tumors were pleomorphic adenomas (68.4%) and benign tumors were significantly more frequent in the parotid (75.9%), while malignant tumors were more frequent in the minor salivary glands (40%) (P < 0.05).
  • In conclusion, women and the parotid gland were the most affected and pleomorphic adenoma was the most frequent lesion, followed by adenoid cystic carcinoma and Warthin's tumor.

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  • (PMID = 20596844.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 15
  • [Other-IDs] NLM/ PMC2811571
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90. Smith SL, Komisar A: Limited parotidectomy: the role of extracapsular dissection in parotid gland neoplasms. Laryngoscope; 2007 Jul;117(7):1163-7
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  • OBJECTIVE: Surgical techniques for parotid gland neoplasm removal have been shaped over the years by the importance of the gland's relationship with the facial nerve, histologic behavior of parotid tumors, and recurrence rates from specific techniques.
  • RESULTS: All tumors were located in the superficial lobe of the parotid gland and size of the masses ranged from 4.0 to 1.0 cm (mean 2.4 cm) in diameter.
  • Pathology of the parotid tumors consisted of 11 pleomorphic adenomas, six Warthin's tumors, six benign epithelial cysts, one sarcoid lesion, two lymphoid hyperplasia, and one Kaposi's sarcoma.

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  • [CommentIn] Laryngoscope. 2008 Feb;118(2):379; author reply 379-80 [18303396.001]
  • (PMID = 17632913.001).
  • [ISSN] 0023-852X
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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91. Sadetzki S, Oberman B, Mandelzweig L, Chetrit A, Ben-Tal T, Jarus-Hakak A, Duvdevani S, Cardis E, Wolf M: Smoking and risk of parotid gland tumors: a nationwide case-control study. Cancer; 2008 May 1;112(9):1974-82
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Smoking and risk of parotid gland tumors: a nationwide case-control study.
  • BACKGROUND: Because existing data regarding the relation between smoking and salivary gland tumors are sparse, tobacco is currently not classified as a salivary gland carcinogen.
  • The objective of the current study was to assess the association between smoking and benign and malignant parotid gland tumors (PGTs) in a nationwide study.
  • Analysis by histologic type indicated remarkably high risks for Warthin tumor (OR for ever cigarette smokers: 15.3; 95% CI, 6.1-38.5).
  • For pleomorphic adenomas and malignant tumors, the risks associated with ever smoking were 1.01 (95% CI, 0.75-1.37) and 1.69 (95% CI, 0.81-3.51), respectively.
  • CONCLUSIONS: Smoking plays an important role in the development of Warthin tumor.
  • Although no association was observed for pleomorphic adenoma, the possible indication of increased risk of malignant tumors requires further investigation in larger studies.

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  • [ErratumIn] Cancer. 2008 Aug 1;113(3):662-3
  • (PMID = 18361448.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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92. Al Salamah SM, Khalid K, Khan IA, Gul R: Outcome of surgery for parotid tumours: 5-year experience of a general surgical unit in a teaching hospital. ANZ J Surg; 2005 Nov;75(11):948-52
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  • Pleomorphic adenoma was the commonest pathology observed in 24 patients (64.9%).
  • Warthin's tumour was more common among male patients and was the only pathology with bilateral involvement.
  • Malignant tumour was found in five patients (13.5%).
  • [MeSH-minor] Adenoma, Pleomorphic / pathology. Adenoma, Pleomorphic / surgery. Adolescent. Adult. Aged. Biopsy, Fine-Needle. Facial Nerve Diseases / etiology. Female. Follow-Up Studies. Humans. Male. Middle Aged. Postoperative Complications. Prospective Studies. Treatment Outcome

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  • (PMID = 16336383.001).
  • [ISSN] 1445-1433
  • [Journal-full-title] ANZ journal of surgery
  • [ISO-abbreviation] ANZ J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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93. Lee SK, Rho BH, Won KS: Parotid incidentaloma identified by combined 18F-fluorodeoxyglucose whole-body positron emission tomography and computed tomography: findings at grayscale and power Doppler ultrasonography and ultrasound-guided fine-needle aspiration biopsy or core-needle biopsy. Eur Radiol; 2009 Sep;19(9):2268-74
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  • The results of ultrasound-guided fine-needle aspiration biopsy (FNAB) (n = 9) and core-needle biopsy (CNB) (n = 3) were Warthin tumor in 10 cases, and pleomorphic adenoma and chronic inflammation in one each.
  • SUV(max) was 7.0-21.0 g/mL (average 13.7 g/mL) for Warthin tumor, 6.8 g/mL for pleomorphic adenoma, and 7.3 g/mL for chronic inflammation.
  • Parotid incidentaloma identified by 18F-FDG PET/CT during workup of various malignancies elsewhere does not necessarily signify primary or metastatic malignancy, but indicates a high likelihood of benign lesions, particularly Warthin tumor.
  • Such lesions should be evaluated thoroughly by US and ultrasound-guided FNAB or CNB if parotid disease would change the patient's treatment plan.
  • [MeSH-major] Adenoma / diagnosis. Biopsy, Fine-Needle / methods. Fluorodeoxyglucose F18. Parotid Neoplasms / diagnosis. Positron-Emission Tomography / methods. Tomography, X-Ray Computed / methods. Ultrasonography, Doppler / methods

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  • [Cites] Laryngoscope. 2001 Nov;111(11 Pt 1):1989-92 [11801984.001]
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  • (PMID = 19396445.001).
  • [ISSN] 1432-1084
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Comparative Study; Evaluation Studies; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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94. Colella G, Tozzi U, Pagliarulo V, Bove P: Warthin tumor: a potential source of diagnostic error. J Craniofac Surg; 2010 Nov;21(6):1978-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Warthin tumor: a potential source of diagnostic error.
  • PURPOSE: Warthin tumor, also known as papillary cystadenoma lymphomatosum, is a fairly common tumor.
  • It makes up 14% to 30% of parotid tumors.
  • There has been much interest in this tumor because of its typical and intriguing morphologic features: the association of benign-looking lymphoid and epithelial components and its frequent occurrence in the intraparotid or periparotid lymph nodes.
  • Moreover, multifocal and/or bilateral Warthin tumors have been reported, and malignant transformation of Warthin tumor and its association with other malignancies have been documented.
  • Warthin tumor can sometimes be confused with other pathologic lesions because of symptoms and signs that accompany the disease, so it could be treated as other pathologic lesions.
  • The first one had a differentiated squamous cell carcinoma, no lymph node metastasis, and a Warthin tumor of the left parotid gland.
  • RESULTS AND CONCLUSIONS: The aim of this study was to evaluate the clinical and histopathologic features of 3 cases where clinical presentation of a Warthin tumor lies in the possible errors in diagnosis and decision making and not least in the management of the patient.
  • [MeSH-major] Adenolymphoma / diagnosis. Diagnostic Errors. Parotid Neoplasms / diagnosis

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  • (PMID = 21119475.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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95. Pietniczka-Załeska M, Kukwa A: [The parotid gland's tumours in material of Otolaryngology Department Medical Academy in Warsaw in 1990-2006]. Otolaryngol Pol; 2008;62(4):395-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The most frequent tumours were pleomorphic adenoma and adenolymphoma.
  • (1) There were 81% cases of benign neoplasm and 19% malignant neoplasm in presented material. (2) The result of parotid gland treatment depends on tumor's histopathology, the period of disease, the size of tumour, its expansion into the neighbourhood, infiltrating of the facial nerve and metastases into the lymph nodes. (3) Radical resection of tumour and metastases, reconstructing the continuity of tissues and maintaining the quality of patients life, should be the principle of surgical treatment.

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  • (PMID = 18837210.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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96. Du M, Ma GZ, Nie MH: [Warthin's tumor (adenolymphoma) with squamous metaplasia and carcinomatous transformation: report of a case]. Zhonghua Bing Li Xue Za Zhi; 2005 Dec;34(12):827
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Warthin's tumor (adenolymphoma) with squamous metaplasia and carcinomatous transformation: report of a case].
  • [MeSH-major] Adenolymphoma / pathology. Carcinoma, Squamous Cell / pathology. Parotid Neoplasms / pathology

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  • (PMID = 16545203.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / CK-34 beta E12; 0 / Ki-67 Antigen; 68238-35-7 / Keratins
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97. Peter Klussmann J, Wittekindt C, Florian Preuss S, Al Attab A, Schroeder U, Guntinas-Lichius O: High risk for bilateral Warthin tumor in heavy smokers--review of 185 cases. Acta Otolaryngol; 2006 Dec;126(11):1213-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] High risk for bilateral Warthin tumor in heavy smokers--review of 185 cases.
  • CONCLUSIONS: We identified smoking as a significant risk factor for multilocular Warthin tumor development.
  • OBJECTIVES: Warthin tumor is a common benign neoplasm of the parotid gland.
  • PATIENTS AND METHODS: A total of 185 consecutive patients treated for Warthin tumor were included.
  • Bilateral Warthin tumor was seen in 17% of patients.
  • Of these cases synchronous and metachronous bilateral tumors were observed in 61% and 39%, respectively.
  • The median time period for second contralateral tumor development was 7 years.
  • The risk for bilateral Warthin tumors correlated significantly with the amount of nicotine intake (p=0.003).
  • [MeSH-major] Adenolymphoma / etiology. Neoplasms, Multiple Primary / etiology. Parotid Neoplasms / etiology. Smoking / adverse effects

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  • (PMID = 17050316.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Norway
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98. Miliauskas JR, Hunt JL: Primary unilateral multifocal pleomorphic adenoma of the parotid gland: molecular assessment and literature review. Head Neck Pathol; 2008 Dec;2(4):339-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary unilateral multifocal pleomorphic adenoma of the parotid gland: molecular assessment and literature review.
  • Multiple separate tumors developing in a single salivary gland is rare in previously untreated patients.
  • Tumors that can be multicentric include Warthin tumor, oncocytoma, basal cell adenoma and acinic cell carcinoma.
  • We report two cases of primary multicentric pleomorphic adenoma and review the literature.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Loss of Heterozygosity. Neoplasms, Multiple Primary / pathology. Parotid Neoplasms / pathology

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  • [Cites] Laryngorhinootologie. 2007 Jun;86(6):448-50 [17219338.001]
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  • (PMID = 20614306.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm
  • [Other-IDs] NLM/ PMC2807582
  • [Keywords] NOTNLM ; Multifocal / Parotid gland / Pleomorphic adenoma
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99. Zarka MA: Epithelioid cell clusters with an extensive lymphoid background. Arch Pathol Lab Med; 2007 Mar;131(3):424-33
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This pattern is often associated with Warthin tumor; however, other benign and malignant entities fall under this diagnostic group.

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  • (PMID = 17516744.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 31
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100. Chan WH, Lee KW, Chiang FY, Ho KY, Chai CY, Kuo WR: Features of parotid gland diseases and surgical results in southern Taiwan. Kaohsiung J Med Sci; 2010 Sep;26(9):483-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Various parotid gland diseases are seen clinically, including inflammation, sialolithiasis, and benign and malignant tumors.
  • Here, we investigated the relationship between tumor characteristics and pathology, and considered whether the former could be used to differentiate malignant from benign parotid gland diseases.
  • Two hundred and eighty-one patients (88.9%) had benign disease, and 35 (11.1%) had malignant disease.
  • The most common benign disease was pleomorphic adenoma (115 cases, 36.4%), but the most common disease in male patients was Warthin's tumor, a finding which, as far as we aware, has not been previously been reported in the literature.
  • The incidence of Warthin's tumor seems to be increasing.
  • In malignant disease, the most common was acinic cell carcinoma (8 cases, 22.9%).
  • Compared with benign disease, malignant parotid gland disease more often presents as a hard, painful, fixed and large mass (> 3 cm), and more often involves the deep lobe of the parotid gland.
  • Partial parotidectomy was adequate for most tumors, including pleomorphic adenoma.
  • However, there was no difference in transient facial palsy rate between benign and malignant parotid gland disease, although parotid gland cancer had a higher incidence of permanent facial palsy postoperatively.

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  • [Copyright] Copyright © 2010 Elsevier. Published by Elsevier B.V. All rights reserved.
  • [CommentIn] Kaohsiung J Med Sci. 2012 Jun;28(6):350-1 [22632893.001]
  • (PMID = 20837345.001).
  • [ISSN] 1607-551X
  • [Journal-full-title] The Kaohsiung journal of medical sciences
  • [ISO-abbreviation] Kaohsiung J. Med. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China (Republic : 1949- )
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