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11. Roviaro G, Vergani C, Maciocco M, Varoli F, Francese M, Despini L: Tracheal sleeve pneumonectomy: long-term outcome. Lung Cancer; 2006 Apr;52(1):105-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adenocarcinoma / surgery. Carcinoma, Adenoid Cystic / surgery. Carcinoma, Large Cell / surgery. Carcinoma, Squamous Cell / surgery. Humans. Pleural Neoplasms / secondary. Pleural Neoplasms / surgery. Prognosis. Survival Rate. Thoracotomy. Trachea

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  • (PMID = 16481067.001).
  • [ISSN] 0169-5002
  • [Journal-full-title] Lung cancer (Amsterdam, Netherlands)
  • [ISO-abbreviation] Lung Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
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12. Aksu K, Aktaş Z, Aksu F, Orsel O, Demirağ F, Sipit T, Firat Güven S: Spindle cell sarcomatoid carcinoma: first case reported in the trachea. Tuberk Toraks; 2009;57(3):337-41
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  • [Title] Spindle cell sarcomatoid carcinoma: first case reported in the trachea.
  • Microscopically, the tumor was composed of fascicular pattern of spindle cells with atypical mitotic figures and nuclear pleomorphism, positively reactive to epithelial membrane antigen supporting a diagnosis of tumour with epithelial differentiation.
  • These findings supported the diagnosis of a spindle cell sarcomatoid carcinoma of trachea.
  • Spindle cell carcinoma cases are reported in many sites, such as head and neck region, larynx, digestive tract, breast, kidney, genital tract, skin and lung, but to our knowledge, not in trachea.
  • Primary malignant tracheal tumours consist mainly of squamous cell carcinoma and adenoid cystic carcinoma and generally have an aggressive course with poor prognosis.
  • We report the first presentation of a spindle cell sarcomatoid carcinoma of trachea together with the clinical course of the patient.
  • [MeSH-major] Carcinoma / pathology. Tracheal Neoplasms / pathology

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  • (PMID = 19787474.001).
  • [ISSN] 0494-1373
  • [Journal-full-title] Tüberküloz ve toraks
  • [ISO-abbreviation] Tuberk Toraks
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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13. Tang X, He D, Hua C: [Reconstruction of oral muco-defects with buccal fat pad flap]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2006 Sep;20(9):893-5
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  • The defect was caused by buccal squamous carcinoma in 7 cases, by buccal leukoplakia in 5 cases, by squamous carcinoma of soft palate in 7 cases, by adenoid cystic carcinoma of palate in 8 cases, by carcinoma of maxillary sinus in 6 cases, by maxillo-alveolar angioma in 5 cases and by keratocyst of maxilla in 4 cases.
  • [MeSH-minor] Adult. Aged. Carcinoma, Squamous Cell / surgery. Female. Follow-Up Studies. Humans. Male. Maxillary Neoplasms / surgery. Middle Aged. Mouth Neoplasms / surgery. Oral Surgical Procedures / methods. Palatal Neoplasms / surgery

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  • (PMID = 17036974.001).
  • [ISSN] 1002-1892
  • [Journal-full-title] Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
  • [ISO-abbreviation] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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1
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4. Patel AA, Gupta D, Seligson D, Hattab EM, Balis UJ, Ulbright TM, Kohane IS, Berman JJ, Gilbertson JR, Dry S, Schirripa O, Yu H, Becich MJ, Parwani AV, Shared Pathology Informatics Network: Availability and quality of paraffin blocks identified in pathology archives: a multi-institutional study by the Shared Pathology Informatics Network (SPIN). BMC Cancer; 2007 Feb 28;7:37
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Each site generated a list of 100 common tumor cases (25 cases each of breast adenocarcinoma, colonic adenocarcinoma, lung squamous carcinoma, and prostate adenocarcinoma) and 100 rare tumor cases (25 cases each of adrenal cortical carcinoma, gastro-intestinal stromal tumor [GIST], adenoid cystic carcinoma, and mycosis fungoides) using a combination of Tumor Registry, laboratory information system (LIS) and/or SPIN-related tools.
  • Retrieval rate (tumor blocks) from all centers for rare tumors was 66% with mean largest tumor size of 1.56 cm; retrieval (tumor blocks) was highest for GIST (72%) and lowest for adenoid cystic carcinoma (58%).

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  • (PMID = 17386082.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / U01CA091343; United States / NCI NIH HHS / CA / U01 CA091429; United States / NCI NIH HHS / CA / U01CA091429; United States / NCI NIH HHS / CA / P30 CA016042; United States / NCI NIH HHS / CA / U01 CA091343; United States / NCI NIH HHS / CA / UO1CA91338-01
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1810540
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15. Doshi DV, Tripathi U, Dave RI, Pandya SJ, Shukla HK, Parikh BC: Rare tumors of sinonasal track. Indian J Otolaryngol Head Neck Surg; 2010 Jun;62(2):111-7
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  • RESULTS: Eighty-nine cases of the non-squamous cell malignancy were identified.
  • In this study, we found minor salivary gland tumor in 31 patients, sarcoma in 19 patients, spindle cell carcinoma (SpCC) in 19 patients, undifferentiated carcinoma in 9 patients, lymphoma in 6 patients and melanoma in 3 patients.
  • Adenoid cystic carcinoma exhibited the best survival rate (3 years survival rate was 77%), whereas melanoma and undifferentiated carcinoma exhibited poor survivals (1 year survival was 25% and 33%, respectively and 3 years survival rate is 0%).
  • CONCLUSIONS: Adenoid cystic carcinoma is the most common squamous cell carcinoma (SCC) of the sinonasal track.
  • Survival for the patients with undifferentiated carcinoma and melanoma involving the sinonasal track is poor.

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  • (PMID = 23120695.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3450295
  • [Keywords] NOTNLM ; Clinical features / Rare tumor / Sino nasal
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16. Lee C, Langen KM, Lu W, Haimerl J, Schnarr E, Ruchala KJ, Olivera GH, Meeks SL, Kupelian PA, Shellenberger TD, Mañon RR: Assessment of parotid gland dose changes during head and neck cancer radiotherapy using daily megavoltage computed tomography and deformable image registration. Int J Radiat Oncol Biol Phys; 2008 Aug 1;71(5):1563-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Algorithms. Carcinoma, Adenoid Cystic / radiography. Carcinoma, Adenoid Cystic / radiotherapy. Carcinoma, Squamous Cell / radiography. Carcinoma, Squamous Cell / radiotherapy. Humans. Radiotherapy Dosage. Tomography, Spiral Computed

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  • (PMID = 18538505.001).
  • [ISSN] 0360-3016
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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17. Joshi NP, Haresh KP, Das P, Kumar R, Prabhakar R, Sharma DN, Heera P, Julka PK, Rath GK: Unresectable basaloid squamous cell carcinoma of the trachea treated with concurrent chemoradiotherapy: a case report with review of literature. J Cancer Res Ther; 2010 Jul-Sep;6(3):321-3
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  • [Title] Unresectable basaloid squamous cell carcinoma of the trachea treated with concurrent chemoradiotherapy: a case report with review of literature.
  • Basaloid squamous cell carcinoma is an uncommon variant of squamous cell carcinoma of the trachea.
  • We describe the case of an unresectable basaloid squamous cell carcinoma of the trachea treated with concurrent chemoradiotherapy up to a dose of 60 Gy in 33 fractions with weekly paclitaxel and carboplatin.
  • The pathological recognition of basaloid squamous cell carcinoma and its distinction from adenoid cystic carcinoma of the trachea is important for its management.
  • Combining systemic chemotherapy with locoregional radiation is a logical approach to treatment, especially for the basaloid squamous cell carcinoma of the trachea, given its tendency to metastasize early after definitive therapy.
  • [MeSH-major] Carcinoma, Squamous Cell / therapy. Tracheal Neoplasms / therapy

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  • (PMID = 21119264.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
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18. Zidar N, Gale N, Zupevc A, Dovsak D: Pseudovascular adenoid squamous-cell carcinoma of the oral cavity--a report of two cases. J Clin Pathol; 2006 Nov;59(11):1206-8
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  • [Title] Pseudovascular adenoid squamous-cell carcinoma of the oral cavity--a report of two cases.
  • Two cases of pseudovascular adenoid squamous-cell carcinoma (SCC) in the oral cavity are described, which were characterised by acantholysis of the tumour cells, with formation of anastomosing spaces and channels mimicking an angiosarcoma.
  • Both tumours contained foci of SCC suggesting the correct diagnosis: in one patient conventional SCC, and in the other, a spindle-cell carcinoma.
  • The pathogenesis of pseudovascular adenoid SCC is unknown.
  • Pseudovascular adenoid SCC is suggested to be pathogenetically related to the loss of E-cadherin expression, leading to the loss of tumour cell-cell adhesion.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Mouth Neoplasms / pathology
  • [MeSH-minor] Aged. Cadherins / metabolism. Diagnosis, Differential. Female. Hemangiosarcoma / pathology. Humans. Male. Middle Aged. Neoplasm Proteins / metabolism


19. Kenzaki K, Sakiyama S, Toba H, Nakagawa Y, Takizawa H, Kondo K, Tangoku A: [Clinical analysis of tracheoplasty and bronchoplasty in primary lung cancer]. Kyobu Geka; 2008 Oct;61(11):951-6
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  • The tissue forms were 19 squamous cell carcinomas, 2 adenocarcinomas, 1 large cell carcinoma, 1 adenoid cystic carcinoma and 1 carcinoid, including 2 multiple carcinomas.

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  • (PMID = 18939431.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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20. Feichtinger M, Pau M, Zemann W, Aigner RM, Kärcher H: Intraoperative control of resection margins in advanced head and neck cancer using a 3D-navigation system based on PET/CT image fusion. J Craniomaxillofac Surg; 2010 Dec;38(8):589-94
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Carcinoma, Adenoid Cystic / surgery. Carcinoma, Squamous Cell / surgery. Head and Neck Neoplasms / surgery. Imaging, Three-Dimensional / methods. Surgery, Computer-Assisted / methods

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  • [Copyright] Copyright © 2010 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 20381368.001).
  • [ISSN] 1878-4119
  • [Journal-full-title] Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
  • [ISO-abbreviation] J Craniomaxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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21. Moore MG, Deschler DG, McKenna MJ, Varvares MA, Lin DT: Management outcomes following lateral temporal bone resection for ear and temporal bone malignancies. Otolaryngol Head Neck Surg; 2007 Dec;137(6):893-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: In this group of 35 patients, the mean age was 62.7 years, with tumor histopathologies including squamous cell carcinoma (SCC, 20), basal cell carcinoma (BCC, 7), adenoid cystic carcinoma (ACC, 7), and adenocarcinoma (1).
  • [MeSH-minor] Adenocarcinoma / surgery. Carcinoma, Adenoid Cystic / surgery. Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / surgery. Disease-Free Survival. Ear Canal / surgery. Ear, External / surgery. Ear, Middle / surgery. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Recurrence, Local / pathology. Neoplasm Staging. Parotid Gland / surgery. Retrospective Studies. Survival Rate. Treatment Outcome

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  • (PMID = 18036417.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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22. Bilsky MH, Bentz B, Vitaz T, Shah J, Kraus D: Craniofacial resection for cranial base malignancies involving the infratemporal fossa. Neurosurgery; 2005 Oct;57(4 Suppl):339-47; discussion 339-47
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  • Advanced operative techniques have made tumor resection feasible in an en bloc fashion with negative histological margins, but there are limited data regarding outcome analysis in patients who have undergone resection of malignant tumors in this area.
  • The most common tumors were sarcoma (n = 9), squamous cell carcinoma (n = 6), and adenoid cystic carcinoma (n = 3).

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  • (PMID = 16234683.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / T32 CA009685
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS15707; NLM/ PMC1858642
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23. Kummoona R, Mohammad Sámi S, Al-Kapptan I, Al-Muala H: Study of antiapoptotic gene of oral carcinoma by using Bcl-2 oncogene. J Oral Pathol Med; 2008 Jul;37(6):345-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Study of antiapoptotic gene of oral carcinoma by using Bcl-2 oncogene.
  • The present study was addressed to find out the expression of Bcl-2 proto-oncogene in tumor tissue derived from 24 patients with malignant oral carcinoma and oral mucosa from the same patients served as control and showed a cytoplasmic pattern of Bcl-2 immunoreactivity in basal cell layer.
  • Fourteen of 24 (58.3%) of oral carcinoma and four adenocystic carcinoma expressed positive Bcl-2 oncogene.
  • Well-differentiated squamous cell carcinoma showed absence of immunoreactivity.
  • We propose from this study that overexpression of Bcl-2 proto-oncogene acts as a strong antiapoptotic in both squamous cells and adenocystic carcinoma may be an important molecular event on oral carcinoma to make these tumors resistant to radiotherapy and chemotherapy.
  • [MeSH-major] Apoptosis / genetics. Carcinoma, Adenoid Cystic / genetics. Carcinoma, Squamous Cell / genetics. Genes, bcl-2 / genetics. Mouth Neoplasms / genetics. bcl-Associated Death Protein / genetics
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Gene Expression. Gene Expression Regulation, Neoplastic. Humans. Male. Middle Aged. Neoplasm Staging

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  • (PMID = 18248353.001).
  • [ISSN] 1600-0714
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / bcl-Associated Death Protein
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24. Pradhan D, Pattnaik K, Pahi J, Mohanty P, Satpathy S, Behuria S: Adenoid cystic carcinoma in the uterine cervix: a case report. Acta Cytol; 2010 Sep-Oct;54(5 Suppl):1039-42
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  • [Title] Adenoid cystic carcinoma in the uterine cervix: a case report.
  • BACKGROUND: Adenoid cystic carcinoma, a variant of adenocarcinoma of the uterine cervix, is an extremely rare neoplasm.
  • This report describes a case of primary adenoid cystic carcinoma of the uterine cervix and includes the cytopathologic and histopathologic findings.
  • A Pap smear was obtained, which showed small epithelial cells with hyperchromatic nuclei and coarse chromatin dispersed and adhered around hyaline stromal globular material, along with a few atypical squamous cells.
  • The diagnosis of adenoid cystic carcinoma was confirmed by the histopathologic examination of the biopsy specimen as well as the excised specimen, which characteristically revealed the presence of a cribriform pattern of the tumor cells.
  • CONCLUSION: We reported a case of a rare and unusual variant of adenocarcinoma of the uterine cervix by considering the characteristic cytologic features of the globules of pale, translucent material surrounded by halos of cells in cribriform adenoid cystic carcinoma.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Cervix Uteri / pathology. Uterine Cervical Neoplasms / pathology


25. Tsujii H, Mizoe J, Kamada T, Baba M, Tsuji H, Kato H, Kato S, Yamada S, Yasuda S, Ohno T, Yanagi T, Imai R, Kagei K, Kato H, Hara R, Hasegawa A, Nakajima M, Sugane N, Tamaki N, Takagi R, Kandatsu S, Yoshikawa K, Kishimoto R, Miyamoto T: Clinical Results of Carbon Ion Radiotherapy at NIRS. J Radiat Res; 2007;48 Suppl A:A1-A13
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  • Tumors that appear to respond favorably to carbon ions include locally advanced tumors and those with histologically non-squamous cell type of tumors such as adenocarcinoma, adenoid cystic carcinoma, malignant melanoma, hepatoma, and bone/soft tissue sarcoma.
  • [MeSH-minor] Carbon / therapeutic use. Carcinoma, Hepatocellular. Humans. Liver Neoplasms / radiotherapy. Neoplasms / radiotherapy

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  • (PMID = 17513896.001).
  • [ISSN] 1349-9157
  • [Journal-full-title] Journal of radiation research
  • [ISO-abbreviation] J. Radiat. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 7440-44-0 / Carbon
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26. Hanna E, DeMonte F, Ibrahim S, Roberts D, Levine N, Kupferman M: Endoscopic resection of sinonasal cancers with and without craniotomy: oncologic results. Arch Otolaryngol Head Neck Surg; 2009 Dec;135(12):1219-24
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  • PATIENTS: All patients with biopsy-proved malignant neoplasm of the sinonasal region who were treated with endoscopic resection between 1992 and 2007 were included in the study, and their charts were reviewed for demographics, histopathologic findings, treatment details, and outcome.
  • The most common tumor types were esthesioneuroblastoma (17%), sarcoma (15%), adenocarcinoma (14%), melanoma (14%), and squamous cell carcinoma (13%).
  • Other, less common tumors included adenoid cystic carcinoma (7%), neuroendocrine carcinoma (4%), and sinonasal undifferentiated carcinoma (2%).
  • CONCLUSIONS: To the best of our knowledge, this is the largest US series to date of patients with malignant tumors of the sinonasal tract treated with endoscopic resection.
  • [MeSH-minor] Adenocarcinoma / surgery. Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Squamous Cell / surgery. Chemotherapy, Adjuvant. Child. Craniotomy. Disease-Free Survival. Esthesioneuroblastoma, Olfactory / surgery. Ethmoid Sinus. Female. Humans. Male. Melanoma / surgery. Middle Aged. Neoplasm Recurrence, Local. Nose Neoplasms / mortality. Nose Neoplasms / surgery. Radiotherapy, Adjuvant. Retrospective Studies. Sarcoma / surgery


27. Parwani AV, Smith Sehdev AE, Kurman RJ, Ronnett BM: Cervical adenoid basal tumors comprised of adenoid basal epithelioma associated with various types of invasive carcinoma: clinicopathologic features, human papillomavirus DNA detection, and P16 expression. Hum Pathol; 2005 Jan;36(1):82-90
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  • [Title] Cervical adenoid basal tumors comprised of adenoid basal epithelioma associated with various types of invasive carcinoma: clinicopathologic features, human papillomavirus DNA detection, and P16 expression.
  • Adenoid basal tumors are uncommon cervical lesions that some pathologists consider invasive carcinomas but others consider "epitheliomas" due to their low-grade histological appearance and rarely documented malignant behavior.
  • We report the clinicopathologic features of 10 tumors comprised of both typical low-grade adenoid basal tumors (epitheliomas) intimately associated with invasive carcinomas having infiltrative growth, increased cytological atypia and mitotic activity, and various types of differentiation, including adenoid basal/squamous, pure squamous, adenoid cystic, and small cell neuroendocrine.
  • The initial diagnosis was made on specimens obtained by cervical biopsy, laser electrocautery excision procedure (LEEP), or cone biopsy in 8 patients.
  • All 10 patients had squamous intraepithelial lesions (9 high-grade, 1 low-grade).
  • In all cases diagnosed in LEEP or cone biopsy specimens, the invasive carcinoma component was present in the excisional specimen and extended to the margins.
  • One patient with a component of small cell carcinoma died of other causes without evidence of disease at 18 months.
  • HPV 16 DNA was detected in both the adenoid basal epithelioma and invasive carcinoma components in 9 tumors by in situ hybridization, and HPV 33 was detected by polymerase chain reaction in 1 tumor.
  • Adenoid basal tumors are high-risk HPV-related tumors that can be comprised of both a low-grade adenoid basal tumor, which can be designated as epithelioma, and invasive carcinomas of various types.
  • [MeSH-major] Carcinoma, Basal Cell / classification. Carcinoma, Basal Cell / pathology. Cyclin-Dependent Kinase Inhibitor p16 / metabolism. DNA, Viral / isolation & purification. Uterine Cervical Neoplasms / classification. Uterine Cervical Neoplasms / pathology


28. Chang CH, Shu MT, Lee JC, Leu YS, Chen YC, Lee KS: Treatments and outcomes of malignant tumors of external auditory canal. Am J Otolaryngol; 2009 Jan-Feb;30(1):44-8
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  • [Title] Treatments and outcomes of malignant tumors of external auditory canal.
  • The purpose of this study is to evaluate the treatment modalities and outcomes for malignant tumors of EAC at our institute, comparing with other studies.
  • RESULTS: Ten patients had squamous cell carcinoma and 2 had adenoid cystic carcinoma (ACC).
  • Only one patient with complete resection had recurrence and the histologic diagnosis of this particular patient was ACC.
  • [MeSH-major] Ear Canal / pathology. Ear Neoplasms / mortality. Ear Neoplasms / therapy. Neoplasm Recurrence, Local / mortality
  • [MeSH-minor] Adult. Aged. Carcinoma, Adenoid Cystic / mortality. Carcinoma, Adenoid Cystic / pathology. Carcinoma, Adenoid Cystic / therapy. Carcinoma, Squamous Cell / mortality. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / therapy. Cohort Studies. Combined Modality Therapy. Disease-Free Survival. Female. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Staging. Otologic Surgical Procedures / methods. Prognosis. Radiotherapy, Adjuvant. Retrospective Studies. Survival Rate. Taiwan

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  • (PMID = 19027512.001).
  • [ISSN] 1532-818X
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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29. De Dosso S, Mazzucchelli L, Ghielmini M, Saletti P: Response to oxaliplatin with cetuximab in minor salivary gland adenoid cystic carcinoma. Tumori; 2009 May-Jun;95(3):378-81
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  • [Title] Response to oxaliplatin with cetuximab in minor salivary gland adenoid cystic carcinoma.
  • Esophageal localization of adenoid cystic carcinoma of minor salivary glands is rare; it may occur in the early to mid-sixties' age group and is more frequently encountered in men than women.
  • In the majority of cases, it arises from subepithelial glands of the middle to lower third of the esophagus, a similar distribution as squamous cell carcinoma.
  • We report a case of a patient with metastatic primary esophageal adenoid cystic carcinoma progressing on platinum- and irinotecan-based regimens, who achieved an objective response with oxaliplatin-based chemotherapy in combination with cetuximab.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinoma, Adenoid Cystic / drug therapy. Carcinoma, Adenoid Cystic / secondary. Esophageal Neoplasms / pathology. Salivary Gland Neoplasms / drug therapy. Salivary Gland Neoplasms / secondary

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  • (PMID = 19688981.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 0 / Biomarkers, Tumor; 0 / Organoplatinum Compounds; 04ZR38536J / oxaliplatin; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; PQX0D8J21J / Cetuximab
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30. Yu Y, Baras AS, Shirasuna K, Frierson HF Jr, Moskaluk CA: Concurrent loss of heterozygosity and copy number analysis in adenoid cystic carcinoma by SNP genotyping arrays. Lab Invest; 2007 May;87(5):430-9
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  • [Title] Concurrent loss of heterozygosity and copy number analysis in adenoid cystic carcinoma by SNP genotyping arrays.
  • Adenoid cystic carcinoma (ACC) is one of the most common malignancies to arise in the salivary glands, yet very little is known of the genetic alterations that are involved in the pathogenesis of this disease.
  • To further examine the genetic changes that underlie ACC, we analyzed genomic DNA obtained from 22 primary ACC and two ACC-derived cell lines by high-density oligonucleotide single-nucleotide polymorphism genotyping arrays (Affymetrix GeneChip Human Mapping 100K Set).
  • This is in contrast to a much higher rate of genomic alterations detected in a cohort of squamous carcinomas analyzed by the same methods.
  • Our data suggest that gene mutation and/or epigenetic events that cannot be detected by assay of gross alteration of chromosomal structure are likely to underlie the malignant transformation events of this tumor type.
  • [MeSH-major] Carcinoma, Adenoid Cystic / genetics. DNA Mutational Analysis / methods. Gene Dosage. Loss of Heterozygosity. Polymorphism, Single Nucleotide / genetics. Salivary Gland Neoplasms / genetics
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Cell Line, Tumor. Chromosome Deletion. DNA, Neoplasm / analysis. Female. Genetic Predisposition to Disease. Genotype. Humans. Male. Microsatellite Repeats. Middle Aged. Oligonucleotide Array Sequence Analysis

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  • (PMID = 17372589.001).
  • [ISSN] 0023-6837
  • [Journal-full-title] Laboratory investigation; a journal of technical methods and pathology
  • [ISO-abbreviation] Lab. Invest.
  • [Language] eng
  • [Grant] United States / NIDCR NIH HHS / DE / R01DE04694
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm
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31. Maroldi R, Farina D, Borghesi A, Marconi A, Gatti E: Perineural tumor spread. Neuroimaging Clin N Am; 2008 May;18(2):413-29, xi
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  • PNS is more frequently associated with carcinoma arising from minor or major salivary glands (more often adenoid cystic carcinoma), mucosal or cutaneous squamous cell carcinoma, basal cell carcinoma, melanoma, lymphoma, and sarcoma.
  • [MeSH-major] Cranial Nerve Neoplasms / diagnosis. Cranial Nerve Neoplasms / secondary. Head and Neck Neoplasms / diagnosis. Head and Neck Neoplasms / secondary
  • [MeSH-minor] Humans. Magnetic Resonance Imaging. Neoplasm Invasiveness. Tomography, X-Ray Computed

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  • (PMID = 18466839.001).
  • [ISSN] 1052-5149
  • [Journal-full-title] Neuroimaging clinics of North America
  • [ISO-abbreviation] Neuroimaging Clin. N. Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 60
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32. Cassarino DS, Derienzo DP, Barr RJ: Cutaneous squamous cell carcinoma: a comprehensive clinicopathologic classification--part two. J Cutan Pathol; 2006 Apr;33(4):261-79
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  • [Title] Cutaneous squamous cell carcinoma: a comprehensive clinicopathologic classification--part two.
  • Cutaneous squamous cell carcinoma (SCC) includes many subtypes with widely varying clinical behaviors, ranging from indolent to aggressive tumors with significant metastatic potential.
  • However, the tendency for pathologists and clinicians alike is to refer to all squamoid neoplasms as generic SCC.
  • Therefore, we have proposed the following based upon the malignant potential of SCC variants, separating them into categories of low (< or = 2% metastatic rate), intermediate (3-10%), high (greater than 10%), and indeterminate behavior.
  • Low-risk SCCs include SCC arising in actinic keratosis, HPV-associated SCC, tricholemmal carcinoma, and spindle cell SCC (unassociated with radiation).
  • Intermediate-risk SCCs include adenoid (acantholytic) SCC, intraepidermal epithelioma with invasion, and lymphoepithelioma-like carcinoma of the skin.
  • High-risk subtypes include de novo SCC, SCC arising in association with predisposing factors (radiation, burn scars, and immunosuppression), invasive Bowen's disease, adenosquamous carcinoma, and malignant proliferating pilar tumors.
  • The indeterminate category includes signet ring cell SCC, follicular SCC, papillary SCC, SCC arising in adnexal cysts, squamoid eccrine ductal carcinoma, and clear-cell SCC.
  • Subclassification of SCC into these risk-based categories, along with enumeration of other factors including tumor size, differentiation, depth of invasion, and perineural invasion will provide prognostically relevant information and facilitate the most optimal treatment for patients.
  • [MeSH-major] Carcinoma, Squamous Cell / classification. Carcinoma, Squamous Cell / pathology. Skin Neoplasms / classification. Skin Neoplasms / pathology
  • [MeSH-minor] Dermatology / methods. Diagnosis, Differential. Humans. Neoplastic Processes. Pathology, Surgical / methods. Risk Factors


33. Cassarino DS, Derienzo DP, Barr RJ: Cutaneous squamous cell carcinoma: a comprehensive clinicopathologic classification. Part one. J Cutan Pathol; 2006 Mar;33(3):191-206
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  • [Title] Cutaneous squamous cell carcinoma: a comprehensive clinicopathologic classification. Part one.
  • Cutaneous squamous cell carcinoma (SCC) includes many subtypes with widely varying clinical behaviors, ranging from indolent to aggressive tumors with significant metastatic potential.
  • However, the tendency for pathologists and clinicians alike is to refer to all squamoid neoplasms as generic SCC.
  • Therefore, we have proposed the following based upon the malignant potential of SCC variants, separating them into categories of low (< or = 2% metastatic rate), intermediate (3-10%), high (greater than 10%), and indeterminate behavior.
  • Low-risk SCCs include SCC arising in actinic keratosis, HPV-associated SCC, tricholemmal carcinoma, and spindle cell SCC (unassociated with radiation).
  • Intermediate-risk SCCs include adenoid (acantholytic) SCC, intraepidermal epithelioma with invasion, and lymphoepithelioma-like carcinoma of the skin.
  • High-risk subtypes include de novo SCC, SCC arising in association with predisposing factors (radiation, burn scars, and immunosuppression), invasive Bowen's disease, adenosquamous carcinoma, and malignant proliferating pilar tumors.
  • The indeterminate category includes signet ring cell SCC, follicular SCC, papillary SCC, SCC arising in adnexal cysts, squamoid eccrine ductal carcinoma, and clear-cell SCC.
  • Subclassification of SCC into these risk-based categories, along with enumeration of other factors including tumor size, differentiation, depth of invasion, and perineural invasion will provide prognostically relevant information and facilitate the most optimal treatment for patients.
  • [MeSH-major] Carcinoma, Squamous Cell / classification. Carcinoma, Squamous Cell / pathology. Skin Neoplasms / classification. Skin Neoplasms / pathology
  • [MeSH-minor] Dermatology / methods. Diagnosis, Differential. Humans. Neoplastic Processes. Pathology, Surgical / methods. Risk Factors


34. Desai SC, Sung CK, Jang DW, Genden EM: Transoral robotic surgery using a carbon dioxide flexible laser for tumors of the upper aerodigestive tract. Laryngoscope; 2008 Dec;118(12):2187-9
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  • RESULTS: Seven male patients with early carcinoma of the oropharynx or larynx successfully underwent tumor extirpation with the transoral robot and the flexible CO2 laser.
  • The final pathology revealed seven patients with squamous cell carcinoma and one patient with adenoid cystic carcinoma.
  • [MeSH-major] Carcinoma, Adenoid Cystic / surgery. Carcinoma, Squamous Cell / surgery. Laryngeal Neoplasms / surgery. Laryngoscopes. Laser Therapy / instrumentation. Lasers, Gas / therapeutic use. Oropharyngeal Neoplasms / surgery. Robotics / instrumentation. Surgery, Computer-Assisted / instrumentation
  • [MeSH-minor] Equipment Design. Equipment Safety. Feasibility Studies. Female. Humans. Male. Neoplasm Staging. Pilot Projects. Prospective Studies. Surgical Flaps. Tissue and Organ Harvesting / instrumentation. Treatment Outcome

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  • (PMID = 19029867.001).
  • [ISSN] 1531-4995
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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35. Mao N, Zuo C, Gan N, Zhu J, Huang D, Liu D, Xie T, Pan H, Huang Y: [Trachea-bronchoplasty in the treatment of centrally located lung cancer]. Zhongguo Fei Ai Za Zhi; 2005 Aug 20;8(4):329-31
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  • There were 49 cases of squamous cell carcinoma, 16 adenocarcinoma, 7 adenosquamous carcinoma, 3 small cell lung cancer and 1 adenoid cystic adenocarcinoma.

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  • (PMID = 21108894.001).
  • [ISSN] 1009-3419
  • [Journal-full-title] Zhongguo fei ai za zhi = Chinese journal of lung cancer
  • [ISO-abbreviation] Zhongguo Fei Ai Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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36. Das S, Kirsch CF: Imaging of lumps and bumps in the nose: a review of sinonasal tumours. Cancer Imaging; 2005;5:167-77
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  • Although sinus tumours are rare, they portend a poor prognosis, often due to advanced disease at diagnosis.
  • Malignant neoplasms reviewed include squamous cell carcinoma, the minor salivary gland tumour, adenoid cystic carcinoma, adenocarcinoma, melanoma, lymphoma, and olfactory neuroblastoma (esthesioneuroblastoma).
  • [MeSH-major] Paranasal Sinus Neoplasms / diagnosis

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  • [Copyright] International Cancer Imaging Society.
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  • (PMID = 16361146.001).
  • [ISSN] 1470-7330
  • [Journal-full-title] Cancer imaging : the official publication of the International Cancer Imaging Society
  • [ISO-abbreviation] Cancer Imaging
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 73
  • [Other-IDs] NLM/ PMC1665243
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37. Ojiri H: Perineural spread in head and neck malignancies. Radiat Med; 2006 Jan;24(1):1-8
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  • Although representative histologies are squamous cell carcinoma and adenoid cystic carcinoma, other malignancies such as malignant lymphoma and sarcoma also can show such a specific pattern of extent.
  • PNS can be insidious, often delaying diagnosis.
  • Knowledge of anatomy of the nerves is crucial in the imaging diagnosis of PNS, to detect early curable disease.
  • [MeSH-major] Cranial Nerve Neoplasms / diagnosis. Cranial Nerve Neoplasms / secondary. Head and Neck Neoplasms / pathology

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  • (PMID = 16715655.001).
  • [ISSN] 0288-2043
  • [Journal-full-title] Radiation medicine
  • [ISO-abbreviation] Radiat Med
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Contrast Media
  • [Number-of-references] 12
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38. Wen SL, Zhou X, Hu HH, Peng ZZ: [Clinical characteristics of 8 cases of primary tracheal tumors]. Zhonghua Jie He He Hu Xi Za Zhi; 2009 Sep;32(9):660-3
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  • OBJECTIVE: To explore the clinical characteristics of primary tracheal tumors and therefore to improve the diagnosis and treatment.
  • Examination by fiberoptic bronchoscopy confirmed the diagnosis of tracheal tumor in all the cases.
  • One case with benign neurinoma and 2 cases with adenoid cystic carcinomas had a long-term postoperative remission.
  • Two cases of squamous cell carcinoma with severe tracheal stenosis got rapid symptom remission after intervention of tracheal stent by fiberoptic bronchoscopy and argon plasma coagulation.
  • One patient with adenoid cystic carcinoma refused any treatment.
  • One patient with squamous cell carcinoma lost follow-up after surgery.
  • Early diagnosis can be made by chest CT and fiberoptic bronchoscopy.
  • Benign tracheal tumors can be resected, and for some low-grade malignant tumors surgical resection and postoperative radiotherapy can improve long term survival.
  • [MeSH-major] Carcinoma, Adenoid Cystic / diagnosis. Carcinoma, Adenoid Cystic / therapy. Tracheal Neoplasms / diagnosis. Tracheal Neoplasms / therapy
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / therapy. Adult. Aged. Carcinoma, Squamous Cell / diagnosis. Carcinoma, Squamous Cell / therapy. Female. Humans. Male. Middle Aged. Retrospective Studies

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  • (PMID = 20079278.001).
  • [ISSN] 1001-0939
  • [Journal-full-title] Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
  • [ISO-abbreviation] Zhonghua Jie He He Hu Xi Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] China
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39. Eslami B, Rahimi H, Rahimi F, Khiavi MM, Ebadifar A: Diagnostic value of silver nitrate staining for nucleolar organizer regions in selected head and neck tumors. J Cancer Res Ther; 2006 Jul-Sep;2(3):129-31
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  • BACKGROUND: The present study is aimed to assess the usefulness of silver nitrate staining of nucleolar organizer regions (NORs) as a quantitative criterion for the diagnosis of selected head and neck tumors.
  • The samples consisted of 21 squamous cell carcinoma (SCC) of larynx, 28 SCC of oral mucosa and 36 samples of most common salivary gland tumors.
  • RESULTS: A significant difference was seen in the number of AgNOR dots between oral and laryngeal SCC with surrounding dysplastic and normal tissues (P < 0.001) and also between mucoepidermoid carcinoma and adenoid cystic carcinoma with pleomorphic adenoma and normal salivary gland tissue (P < 0.001).
  • CONCLUSION: The silver nitrate staining for NORs is a useful method for aiding the diagnosis of malignant and dysplastic mucosal lesions and also malignant and benign salivary gland tumors.
  • [MeSH-major] Carcinoma, Squamous Cell / diagnosis. Head and Neck Neoplasms / diagnosis. Nucleolus Organizer Region / metabolism. Silver Staining
  • [MeSH-minor] Adenoma, Pleomorphic / diagnosis. Adenoma, Pleomorphic / metabolism. Carcinoma, Adenoid Cystic / diagnosis. Carcinoma, Adenoid Cystic / metabolism. Carcinoma, Mucoepidermoid / diagnosis. Carcinoma, Mucoepidermoid / metabolism. Humans. Salivary Gland Neoplasms / diagnosis. Salivary Gland Neoplasms / metabolism

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  • (PMID = 17998691.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
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40. Higgins KM, Backstein R: The submental island flap: a regional and free flap with a myriad of reconstructive applications. J Otolaryngol; 2007 Apr;36(2):88-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Carcinoma, Adenoid Cystic / surgery. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Child. Face / surgery. Lip Neoplasms / pathology. Lip Neoplasms / surgery. Reconstructive Surgical Procedures / methods. Surgical Flaps

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  • (PMID = 17459278.001).
  • [ISSN] 0381-6605
  • [Journal-full-title] The Journal of otolaryngology
  • [ISO-abbreviation] J Otolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Canada
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41. Harada H, Omura K: Metastasis of oral cancer to the parotid node. Eur J Surg Oncol; 2009 Aug;35(8):890-4
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  • The histologic diagnoses of the primary tumors were squamous cell carcinoma in 239 patients, mucoepidermoid carcinoma in 5, adenoid cystic carcinoma in 4, and miscellaneous others in 5.
  • Parotid node involvement occurred in 2.5% of oral squamous cell carcinoma cases.

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  • (PMID = 19004605.001).
  • [ISSN] 1532-2157
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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42. Wu MH: A simple myocutaneous flap for short-stump mediastinal tracheostomy. Ann Thorac Surg; 2009 Sep;88(3):1032-3
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  • The technique was used in 1 patient who had tracheal carcinoma and whose tracheal stump was 1.5 cm and in 2 patients whose posterior part of the tracheal stump was 3 cm and 5 cm, respectively, and who had advanced cervicothoracic esophageal carcinoma.
  • [MeSH-major] Carcinoma, Adenoid Cystic / surgery. Carcinoma, Squamous Cell / surgery. Esophageal Neoplasms / surgery. Surgical Flaps. Tracheal Neoplasms / surgery. Tracheostomy / methods
  • [MeSH-minor] Adult. Aged. Anastomosis, Surgical / methods. Esophagectomy / methods. Esophagus / pathology. Esophagus / surgery. Female. Humans. Laryngectomy / methods. Male. Mediastinum / surgery. Middle Aged. Neoplasm Invasiveness. Suture Techniques. Trachea / pathology. Trachea / surgery

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  • (PMID = 19699959.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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43. Panchal L, Vaideeswar P, Kathpal D, Madiwale CV, Prabhat DP: Sino-nasal epithelial tumours: a pathological study of 69 cases. J Postgrad Med; 2005 Jan-Mar;51(1):30-4; discussion 34-5
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  • The tumours were classified as benign or malignant.
  • Twenty were benign and 49 malignant; occurring predominantly in males.
  • Benign lesions included four squamous papillomas and 16 inverted papillomas, with recurrence in three inverted papillomas (21%).
  • Squamous cell carcinomas were the commonest among malignant tumours and four of these were associated with inverted or cylindrical cell papilloma.
  • The second most frequent malignant tumour was adenoid cystic carcinoma with eight cases.
  • Other rare types included the variants of squamous carcinoma, adenocarcinomas of the non-enteric type, muco-epidermoid carcinoma and undifferentiated carcinomas.
  • Inverted papillomas and squamous cell carcinomas are the most frequent neoplasms.
  • [MeSH-major] Carcinoma / pathology. Papilloma / pathology. Paranasal Sinus Neoplasms / pathology

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  • (PMID = 15793335.001).
  • [ISSN] 0022-3859
  • [Journal-full-title] Journal of postgraduate medicine
  • [ISO-abbreviation] J Postgrad Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
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44. Kuraoka K, Takehara K, Oshita S, Saito A, Taniyama K: Acantholytic squamous cell carcinoma of the uterine cervix. Pathol Int; 2010 Mar;60(3):245-6
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  • [Title] Acantholytic squamous cell carcinoma of the uterine cervix.
  • [MeSH-major] Acantholysis / pathology. Carcinoma, Squamous Cell / pathology. Uterine Cervical Neoplasms / pathology


45. Dallan I, Lenzi R, Sellari-Franceschini S, Tschabitscher M, Muscatello L: Temporalis myofascial flap in maxillary reconstruction: anatomical study and clinical application. J Craniomaxillofac Surg; 2009 Mar;37(2):96-101
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adult. Aged. Cadaver. Carcinoma, Adenoid Cystic / surgery. Carcinoma, Squamous Cell / surgery. Female. Humans. Male. Maxillary Neoplasms / surgery. Middle Aged. Retrospective Studies

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  • (PMID = 19119017.001).
  • [ISSN] 1010-5182
  • [Journal-full-title] Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
  • [ISO-abbreviation] J Craniomaxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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46. Koyfman SA, Abidi A, Ravichandran P, Higgins SA, Azodi M: Adenoid cystic carcinoma of the cervix. Gynecol Oncol; 2005 Nov;99(2):477-80
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  • [Title] Adenoid cystic carcinoma of the cervix.
  • BACKGROUND: Adenoid cystic carcinoma of the cervix is a rare and aggressive neoplasm for which there are no standardized treatment protocols.
  • CASE: A 38-year-old G3P3 Asian female diagnosed with a stage Ib adenoid cystic carcinoma of the cervix with intermediate risk histologic features received a type III hysterectomy in July 2004.
  • CONCLUSION: Patients with stage Ib adenoid cystic carcinoma of the cervix, especially those with histologic features associated with a higher risk of recurrence, should receive aggressive local therapy, following the guidelines established for similarly staged patients with squamous cell carcinoma of the cervix.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Carcinoma, Adenoid Cystic / therapy. Uterine Cervical Neoplasms / pathology. Uterine Cervical Neoplasms / therapy


47. Malata CM, Tehrani H, Kumiponjera D, Hardy DG, Moffat DA: Use of anterolateral thigh and lateral arm fasciocutaneous free flaps in lateral skull base reconstruction. Ann Plast Surg; 2006 Aug;57(2):169-75; discussion 176
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  • Eight patients had squamous cell carcinoma, 3 had infection or osteoradionecrosis, and 1 had adenoid cystic carcinoma.

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  • (PMID = 16861997.001).
  • [ISSN] 0148-7043
  • [Journal-full-title] Annals of plastic surgery
  • [ISO-abbreviation] Ann Plast Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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48. Conde-Taboada A, Flórez A, De la Torre C, Feal C, García-Doval I, Cruces M: Pseudoangiosarcomatous squamous cell carcinoma of skin arising adjacent to decubitus ulcers. Am J Dermatopathol; 2005 Apr;27(2):142-4
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  • [Title] Pseudoangiosarcomatous squamous cell carcinoma of skin arising adjacent to decubitus ulcers.
  • Pseudoangiosarcomatous, or pseudovascular, squamous cell carcinoma of skin is an unusual form of acantholytic (adenoid, pseudoglandular) squamous cell carcinoma that mimics the histolopathologic appearance of angiosarcoma.
  • We report a case of pseudoangiosarcomatous squamous cell carcinoma arising adjacent to decubitus ulcers.
  • To our knowledge, our patient is the first with pseudoangiosarcomatous squamous cell carcinoma of skin developing within decubitus ulcer.
  • [MeSH-major] Carcinoma, Squamous Cell / complications. Pressure Ulcer / complications. Skin Neoplasms / complications
  • [MeSH-minor] Aged. Diagnosis, Differential. Female. Hemangiosarcoma / pathology. Humans. Immunohistochemistry

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  • (PMID = 15798440.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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49. Lin Y, Zhu H, Liu J, Wang H: [Modified sternocleidomastoid myocutaneous flap for reconstruction of soft tissue defects following tumorectomy of maxillofacial region]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2010 Apr;24(4):452-4
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  • There were 27 cases of well-differentiated squamous cell carcinoma (SC), 14 cases of poorly-differentiated SC, 1 case of rhabdomyosarcoma, and 1 case of adenoid cystic carcinoma.
  • The 3 patients with buccal carcinoma could open their mouths normally.
  • The function of deglutition and pronunciation were recovered in 24 patients with tongue carcinoma.

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  • (PMID = 20459009.001).
  • [ISSN] 1002-1892
  • [Journal-full-title] Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
  • [ISO-abbreviation] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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50. Yu P, Roblin P, Chevray P: Internal mammary artery perforator (IMAP) flap for tracheostoma reconstruction. Head Neck; 2006 Aug;28(8):723-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Carcinoma, Adenoid Cystic / surgery. Carcinoma, Squamous Cell / surgery. Glottis. Laryngeal Neoplasms / surgery. Neoplasm Recurrence, Local / surgery. Reconstructive Surgical Procedures. Surgical Flaps / blood supply. Tracheostomy

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  • (PMID = 16619279.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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51. Madison Michael L 2nd, Sorenson JM, Samant S, Robertson JH: The treatment of advanced sinonasal malignancies with pre-operative intra-arterial cisplatin and concurrent radiation. J Neurooncol; 2005 Mar;72(1):67-75
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  • RESULTS: Histopathological analysis of the tumors revealed seven squamous cell carcinomas (64%), two adenocarcinomas (18%), one adenoid cystic carcinoma (9%), and one sinonasal undifferentiated carcinoma (9%).
  • [MeSH-major] Antineoplastic Agents / administration & dosage. Carcinoma / drug therapy. Carcinoma / radiotherapy. Cisplatin / administration & dosage. Paranasal Sinus Neoplasms / drug therapy. Paranasal Sinus Neoplasms / radiotherapy
  • [MeSH-minor] Adenocarcinoma / drug therapy. Adenocarcinoma / pathology. Adenocarcinoma / radiotherapy. Adenocarcinoma / surgery. Adult. Aged. Carcinoma, Squamous Cell / drug therapy. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / radiotherapy. Carcinoma, Squamous Cell / surgery. Female. Humans. Infusions, Intra-Arterial. Male. Middle Aged. Neoadjuvant Therapy / methods. Premedication. Radiation-Sensitizing Agents / administration & dosage. Statistics, Nonparametric. Survival Analysis. Treatment Outcome

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  • (PMID = 15803378.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Radiation-Sensitizing Agents; Q20Q21Q62J / Cisplatin
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52. Blanco M, Egozi L, Lubin D, Poppiti R: Adenoid cystic carcinoma arising in a fibroadenoma. Ann Diagn Pathol; 2005 Jun;9(3):157-9
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  • [Title] Adenoid cystic carcinoma arising in a fibroadenoma.
  • Adenoid cystic carcinoma (ACC) of the breast is a rare neoplasm, accounting for only 0.1 % of all breast carcinomas.
  • Histologic examination showed an adenoid cystic carcinoma with squamous differentiation originating in a fibroadenoma.
  • [MeSH-major] Breast Neoplasms / pathology. Carcinoma, Adenoid Cystic / pathology. Fibroadenoma / pathology. Neoplasms, Second Primary / pathology

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  • (PMID = 15944959.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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53. Hoffmann TK, Sonkoly E, Homey B, Scheckenbach K, Gwosdz C, Bas M, Chaker A, Schirlau K, Whiteside TL: Aberrant cytokine expression in serum of patients with adenoid cystic carcinoma and squamous cell carcinoma of the head and neck. Head Neck; 2007 May;29(5):472-8
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  • [Title] Aberrant cytokine expression in serum of patients with adenoid cystic carcinoma and squamous cell carcinoma of the head and neck.
  • BACKGROUND: Squamous cell carcinoma (SCC) and adenoid cystic carcinoma (ACC) represent 2 clinically important subtypes of head and neck cancer.
  • Our objective was to characterize and compare cytokine profiles in the systemic circulation of patients with SCC and ACC.
  • METHODS: Multiplex analysis of 10 different cytokines (interleukin [IL]-1beta, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, granulocyte-macrophage colony-stimulating factor [GM-CSF], interferon [IFN]-gamma, and tumor necrosis factor [TNF]-alpha) in the serum of patients with SCC (n = 20) and ACC (n = 20) and healthy controls (n = 20) was performed using the Luminex fluorescent-bead technology.
  • RESULTS: Patients with SCC as well as patients with ACC showed an altered cytokine profile compared with healthy individuals.
  • In patients with SCC, significantly elevated serum levels of the proinflammatory cytokines, IL-6 and IL-8, were observed.
  • CONCLUSIONS: A similar serum cytokine profile, with the predominance of proinflammatory cytokines, was observed in patients with SCC and ACC.
  • [MeSH-major] Carcinoma, Adenoid Cystic / blood. Carcinoma, Squamous Cell / blood. Cytokines / blood. Head and Neck Neoplasms / blood


54. Liu FY, Liu XY, Wang Z, Liu Y: [The long-term outcome and prognostic analysis of surgically treated patients with trachea tumors]. Zhonghua Wai Ke Za Zhi; 2009 Jul 15;47(14):1055-7
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  • RESULTS: The histological examination of resected lesions revealed squamous cell carcinoma in 19 cases, adenoid cystic carcinoma in 8 cases, adenocarcinoma in 2 cases, carcinoid in 2 cases, leiomyosarcoma in 1 case and adenoma in 1 case.
  • CONCLUSIONS: Squamous cell carcinoma adenoid cystic carcinoma are the most common in trachea tumors.

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  • (PMID = 19781267.001).
  • [ISSN] 0529-5815
  • [Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]
  • [ISO-abbreviation] Zhonghua Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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55. Vaidhyanath R, Kirke R, Brown L, Sampath R: Lacrimal fossa lesions: pictorial review of CT and MRI features. Orbit; 2008;27(6):410-8
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  • [MeSH-major] Eye Neoplasms / diagnosis. Lacrimal Apparatus Diseases / diagnosis. Magnetic Resonance Imaging. Tomography, X-Ray Computed
  • [MeSH-minor] Adenoma, Pleomorphic / diagnosis. Carcinoma, Adenoid Cystic / diagnosis. Carcinoma, Squamous Cell / diagnosis. Dacryocystitis / diagnosis. Dermoid Cyst / diagnosis. Granulomatosis with Polyangiitis / diagnosis. Humans. Lymphoproliferative Disorders / diagnosis. Sarcoidosis / diagnosis. Sjogren's Syndrome / diagnosis

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  • (PMID = 19085295.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 27
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56. Campos MS, Modolo F, de Oliveira JS, Pinto-Júnior DS, de Sousa SC: Atypical presentation of oral basaloid squamous cell carcinoma. J Contemp Dent Pract; 2009;10(2):98-104
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  • [Title] Atypical presentation of oral basaloid squamous cell carcinoma.
  • AIM: The purpose of this report is to present the clinical and histological features of a basaloid squamous cell carcinoma (BSCC) occurring in the retromolar trigone of a 59-year-old man and to relate its immunohistochemical characteristics.
  • BACKGROUND: BSCC is an aggressive distinct variant of squamous cell carcinoma (SCC) requiring recognition as a separate entity from SCC due to its peculiar behavior.
  • SUMMARY: Since this tumor can mimic other neoplasms such as adenoid cystic carcinoma, neuroendocrine carcinoma, and basal cell adenocarcinoma, histological features are essential to differentiate between them.
  • [MeSH-major] Carcinoma, Squamous Cell / diagnosis. Carcinoma, Transitional Cell / diagnosis. Mouth Neoplasms / diagnosis
  • [MeSH-minor] Adenocarcinoma / diagnosis. Carcinoma, Adenoid Cystic / diagnosis. Carcinoma, Neuroendocrine / diagnosis. Cell Nucleus / ultrastructure. Diagnosis, Differential. Follow-Up Studies. Humans. Immunohistochemistry. Keratins / analysis. Ki-67 Antigen / analysis. Laminin / analysis. Male. Middle Aged. Mitosis. Necrosis. Tumor Suppressor Protein p53 / analysis


57. Okada T, Kamada T, Tsuji H, Mizoe JE, Baba M, Kato S, Yamada S, Sugahara S, Yasuda S, Yamamoto N, Imai R, Hasegawa A, Imada H, Kiyohara H, Jingu K, Shinoto M, Tsujii H: Carbon ion radiotherapy: clinical experiences at National Institute of Radiological Science (NIRS). J Radiat Res; 2010;51(4):355-64
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  • Tumors that appear to respond favorably to carbon ions include locally advanced tumors as well as histologically non-squamous cell tumor types such as adenocarcinoma, adenoid cystic carcinoma, malignant melanoma, hepatoma, and bone/soft tissue sarcoma.
  • [MeSH-minor] Academies and Institutes. Carcinoma, Hepatocellular / radiotherapy. Carcinoma, Non-Small-Cell Lung / radiotherapy. Esophageal Neoplasms / radiotherapy. Female. Humans. Japan. Liver Neoplasms / radiotherapy. Lung Neoplasms / radiotherapy. Male. Pancreatic Neoplasms / radiotherapy. Prostatic Neoplasms / radiotherapy. Rectal Neoplasms / radiotherapy. Uterine Neoplasms / radiotherapy

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  • (PMID = 20508375.001).
  • [ISSN] 1349-9157
  • [Journal-full-title] Journal of radiation research
  • [ISO-abbreviation] J. Radiat. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 7440-44-0 / Carbon
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58. Hansen T, Kunkel M, Weber A, James Kirkpatrick C: Osteonecrosis of the jaws in patients treated with bisphosphonates - histomorphologic analysis in comparison with infected osteoradionecrosis. J Oral Pathol Med; 2006 Mar;35(3):155-60
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  • As similarities between this disorder and infected osteoradionecrosis (IORN) are described, both lesions were compared.
  • METHODS: We investigated eight patients with bisphosphonate treatment and osteonecrosis (four female, four male; median age: 65.6 years; cancer: multiple myeloma in five patients, breast cancer in three patients; mandibular involvement in five patients, maxillar involvement in three cases), and 10 patients suffering from IORN (all male; median age: 61.3 years; cancer: squamous cell carcinoma in nine patients, adenoid cystic carcinoma in one patient; mandibular involvement in all cases).
  • [MeSH-minor] Actinomyces / isolation & purification. Adult. Aged. Aged, 80 and over. Antineoplastic Agents / adverse effects. Bone Density Conservation Agents / adverse effects. Carcinoma, Adenoid Cystic / drug therapy. Carcinoma, Adenoid Cystic / secondary. Carcinoma, Squamous Cell / drug therapy. Carcinoma, Squamous Cell / secondary. Female. Humans. Male. Middle Aged

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  • (PMID = 16454811.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Bone Density Conservation Agents; 0 / Diphosphonates
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59. Ichi T, Shiroma H, Arakaki K, Isa T: [A case of adenoid cystic carcinoma of the thoracic esophagus after neoadjuvant chemotherapy]. Nihon Shokakibyo Gakkai Zasshi; 2010 Feb;107(2):227-32
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  • [Title] [A case of adenoid cystic carcinoma of the thoracic esophagus after neoadjuvant chemotherapy].
  • A 60-year-old man was admitted to our hospital with a tumor in the thoracic esophagus, and squamous cell carcinoma was detected by endoscopic biopsy.
  • The resected specimen showed no residual squamous cell carcinoma but another tumor was found in the submucosal layer which had a cribiform pattern in a solid nest.
  • The tumor cells were positive for S-100 protein and an Alcian-blue-positive substance in the gland, so the tumor was diagnosed as an adenoid-cystic carcinoma.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Esophageal Neoplasms / drug therapy. Esophageal Neoplasms / pathology
  • [MeSH-minor] Carcinoma, Squamous Cell / diagnosis. Diagnosis, Differential. Humans. Male. Middle Aged. Neoadjuvant Therapy

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  • (PMID = 20134125.001).
  • [ISSN] 0446-6586
  • [Journal-full-title] Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
  • [ISO-abbreviation] Nihon Shokakibyo Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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60. Chen AM, Bucci MK, Quivey JM, Garcia J, Eisele DW, Fu KK: Long-term outcome of patients treated by radiation therapy alone for salivary gland carcinomas. Int J Radiat Oncol Biol Phys; 2006 Nov 15;66(4):1044-50
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  • Histology was: 14 mucoepidermoid (31%), 10 adenocarcinoma (22%), 8 adenoid cystic (18%), 4 undifferentiated (9%), 4 acinic (9%), 2 malignant mixed (4%), 2 squamous (4%), and 1 salivary duct carcinoma (2%).
  • [MeSH-major] Carcinoma / radiotherapy. Salivary Gland Neoplasms / radiotherapy

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  • (PMID = 16965870.001).
  • [ISSN] 1879-355X
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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61. Ben-Izhak O, Laster Z, Araidy S, Nagler RM: TUNEL - an efficient prognosis predictor of salivary malignancies. Br J Cancer; 2007 Apr 10;96(7):1101-6
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  • We analysed terminal deoxynucleotidyl transferase (TdT)-mediated biotinylated deoxyuridine-triphosphate (dUTP)-biotin nick-end labelling (TUNEL), p53 and Ki67 expression in 66 patients with malignant salivary tumours by immonohistochemistry, and correlated the data with survival, disease-free survival, tumour grade, stage, and local and distant metastasis.
  • [MeSH-minor] Adenocarcinoma / metabolism. Adenocarcinoma / pathology. Adolescent. Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / metabolism. Carcinoma, Adenoid Cystic / metabolism. Carcinoma, Adenoid Cystic / pathology. Carcinoma, Mucoepidermoid / metabolism. Carcinoma, Mucoepidermoid / pathology. Carcinoma, Squamous Cell / metabolism. Carcinoma, Squamous Cell / pathology. Female. Humans. Ki-67 Antigen / metabolism. Male. Middle Aged. Predictive Value of Tests. Prognosis. Survival Rate. Tumor Suppressor Protein p53 / metabolism

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  • (PMID = 17325701.001).
  • [ISSN] 0007-0920
  • [Journal-full-title] British journal of cancer
  • [ISO-abbreviation] Br. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 0 / Tumor Suppressor Protein p53
  • [Other-IDs] NLM/ PMC2360125
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62. Yu Y, Zhang R, Dai C: [The study on the en bloc resection of the external auditory canal to treat external auditory canal carcinoma in the early stage]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2009 Apr;23(7):313-5
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  • [Title] [The study on the en bloc resection of the external auditory canal to treat external auditory canal carcinoma in the early stage].
  • To improve early diagnosis and the effective surgical management of external auditory canal carcinoma.
  • METHOD: Twelve cases of the early stage external auditory canal carcinoma were reviewed retrospectively.
  • Postoperative pathological diagnosis revealed that 6 cases with adenoid cystic carcinomas, 5 cases of squamous cell carcinomas, 1 case of cerumenal adenocarcinoma.
  • Five cases of squamous cell carcinomas, 1 case of cerumenal adenocarcinoma and 3 cases of adenoid cystic carcinomas received radiotherapy postoperatively.
  • All patients were alive free of carcinoma during the follow-up.
  • CONCLUSION: Timely and accurate biopsy is the key point to diagnose the early stage external auditory canal carcinoma.
  • The complete resection with safety margin of external auditory canal carcinoma can improve the effect of surgery.
  • [MeSH-major] Carcinoma / surgery. Ear Neoplasms / surgery. Ear, External / surgery. Otologic Surgical Procedures / methods
  • [MeSH-minor] Adult. Aged. Female. Humans. Male. Middle Aged. Neoplasm Staging. Prognosis. Retrospective Studies

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  • (PMID = 19670611.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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63. Bellizzi AM, Woodford RL, Moskaluk CA, Jones DR, Kozower BD, Stelow EB: Basaloid squamous cell carcinoma of the esophagus: assessment for high-risk human papillomavirus and related molecular markers. Am J Surg Pathol; 2009 Nov;33(11):1608-14
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  • [Title] Basaloid squamous cell carcinoma of the esophagus: assessment for high-risk human papillomavirus and related molecular markers.
  • Basaloid squamous cell carcinoma (BSCC) of the esophagus is rare, historically confused for adenoid cystic carcinoma, and recently shown to behave similar to conventional, keratinizing esophageal squamous cell carcinoma.
  • HPVs role in esophageal squamous cell carcinomas is less certain, and to our knowledge, a direct examination of esophageal BSCC for high-risk HPV has not been performed earlier.
  • Twenty-two cases of keratinizing esophageal squamous cell carcinoma served as controls.
  • Differential p16 and p53 expression in BSCC suggests that these tumors are molecularly distinct from conventional esophageal squamous cell carcinomas.
  • [MeSH-major] Alphapapillomavirus / isolation & purification. Carcinoma, Basal Cell / virology. Carcinoma, Basosquamous / virology. Carcinoma, Squamous Cell / virology. Esophageal Neoplasms / virology. Papillomavirus Infections / complications


64. Hentschel SJ, Vora Y, Suki D, Hanna EY, DeMonte F: Malignant tumors of the anterolateral skull base. Neurosurgery; 2010 Jan;66(1):102-12; discussion 112
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  • [Title] Malignant tumors of the anterolateral skull base.
  • The most frequently occurring pathologies after the various sarcomas were squamous cell carcinoma (SCC) and adenoid cystic carcinoma (ACC) in 23% and 14% of patients, respectively.
  • The mean PFS (median not reached) for the patients with SCC was 4.6 years, whereas the median PFS for patients with ACC was 3.3 years.


65. Terada T: Esophageal Cancers: A Clinicopathologic and Immunohistochemical Study of 223 Cases. Gastroenterology Res; 2009 Jun;2(3):148-151
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  • There were 223 malignant lesions (23.5%).
  • The number and frequency (percentages) were as follows: 54 mild dysplasia (5.7%), 30 moderate dyplasia (3.2%), 32 severe dysplasia (3.4%), 13 carcinoma in situ (1.4%), 71 squamous cell carcinoma (7.5%), 7 primary adenocarcinoma (0.7%), 1 primary signet ring cell carcinoma (0.1%), 4 primary small cell carcinoma (0.4%), 2 primary amelanotic malignant melanoma (0.2%), 1 primary undifferentiated sarcoma (0.1%), 7 gastric cancer invasion (0.7%), and 1 primary adenoid cystic carcinoma (0.1%).

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  • (PMID = 27933124.001).
  • [ISSN] 1918-2805
  • [Journal-full-title] Gastroenterology research
  • [ISO-abbreviation] Gastroenterology Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
  • [Keywords] NOTNLM ; Benign lesions / Clonicopathologies / Esophagus / Immunohistochemistry / Malignant lesions
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66. Seethala RR, Hunt JL, Baloch ZW, Livolsi VA, Leon Barnes E: Adenoid cystic carcinoma with high-grade transformation: a report of 11 cases and a review of the literature. Am J Surg Pathol; 2007 Nov;31(11):1683-94
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  • [Title] Adenoid cystic carcinoma with high-grade transformation: a report of 11 cases and a review of the literature.
  • High-grade transformation of adenoid cystic carcinoma (ACC) (previously referred to as dedifferentiation) is a rare phenomenon that does not fit into the traditional ACC grading schemes.
  • The most common morphologies for the high-grade component were poorly differentiated cribriform adenocarcinoma and solid undifferentiated carcinoma.
  • [MeSH-major] Adenocarcinoma / pathology. Carcinoma, Adenoid Cystic / pathology. Carcinoma, Papillary / pathology. Carcinoma, Squamous Cell / pathology. Cell Transformation, Neoplastic / pathology. Salivary Gland Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Cell Differentiation. Cell Proliferation. Cyclin D. Cyclins / analysis. Female. Humans. Kaplan-Meier Estimate. Ki-67 Antigen / analysis. Lymph Nodes / pathology. Male. Middle Aged. Mitotic Index. Necrosis. Neoplasm Invasiveness. Neoplasm Staging. Proto-Oncogene Proteins c-kit / analysis. Tumor Suppressor Protein p53 / analysis


67. Seikaly H, Rieger J, O'Connell D, Ansari K, Alqahtani K, Harris J: Beavertail modification of the radial forearm free flap in base of tongue reconstruction: technique and functional outcomes. Head Neck; 2009 Feb;31(2):213-9
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  • [MeSH-major] Carcinoma, Adenoid Cystic / surgery. Carcinoma, Squamous Cell / surgery. Reconstructive Surgical Procedures / methods. Surgical Flaps. Tongue Neoplasms / surgery

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  • (PMID = 19073000.001).
  • [ISSN] 1097-0347
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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68. Valentini V, Fabiani F, Nicolai G, Torroni A, Gennaro P, Marianetti TM, Iannetti G: Use of microvascular free flaps in the reconstruction of the anterior and middle skull base. J Craniofac Surg; 2006 Jul;17(4):790-6
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  • The aim of the present study is to present our experience regarding the use of microvascular free flaps for reconstruction of the anterior or middle skull base after large defects caused by removal of malignant neoplasms.
  • [MeSH-minor] Adolescent. Adult. Aged. Bone Transplantation / methods. Carcinoma, Adenoid Cystic / surgery. Carcinoma, Squamous Cell / surgery. Female. Graft Survival. Hospitalization. Humans. Male. Middle Aged. Muscle, Skeletal / transplantation. Postoperative Complications. Rectus Abdominis / transplantation. Retrospective Studies. Skull Base / surgery. Time Factors. Treatment Outcome

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  • (PMID = 16877936.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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69. Koffi-Aka V, Tano N, Ngouan J, Ehouo F: [Management of cancers of nasal cavities and paranasal sinuses in the ENT Unit at CHU de Treichville (Abidjan)]. Mali Med; 2008;23(4):47-50
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  • [Title] [Management of cancers of nasal cavities and paranasal sinuses in the ENT Unit at CHU de Treichville (Abidjan)].
  • [Transliterated title] Prise en Charge des Cancers Naso-Sinusiens dans le Service D'Orl du CHU de Treichville (Abidjan).
  • The diagnosis was late in the majority of the cases (T > 2: n=5).
  • [MeSH-major] Carcinoma / surgery. Hospital Departments / statistics & numerical data. Hospitals, University / statistics & numerical data. Nasal Cavity. Nose Neoplasms / surgery. Otolaryngology / statistics & numerical data. Paranasal Sinus Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Carcinoma, Adenoid Cystic / epidemiology. Carcinoma, Adenoid Cystic / surgery. Carcinoma, Squamous Cell / epidemiology. Carcinoma, Squamous Cell / surgery. Cote d'Ivoire / epidemiology. Delayed Diagnosis. Female. Humans. Lymph Node Excision. Male. Middle Aged. Retrospective Studies

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  • (PMID = 19617175.001).
  • [ISSN] 1993-0836
  • [Journal-full-title] Le Mali médical
  • [ISO-abbreviation] Mali Med
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Mali
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70. Otsuka H, Graham MM, Kogame M, Nishitani H: The impact of FDG-PET in the management of patients with salivary gland malignancy. Ann Nucl Med; 2005 Dec;19(8):691-4
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  • PATIENTS AND METHODS: We performed 45 FDG PET studies in 31 patients with salivary malignant tumors, using PET (33 studies) and PET/CT (12 studies).
  • Histology consisted of 8 adenocarcinomas, 8 squamous cell carcinomas, 4 adenoid cystic carcinomas, 4 carcinoma ex pleomorphic adenomas, 2 mucoepidermoid carcinomas, 2 poorly differentiated carcinomas, 1 salivary duct carcinoma, 1 lymphoepithelial carcinoma and 1 melanoma.
  • RESULTS: In the initial staging group, all 12 primary lesions (100%) showed positive FDG uptake (5 squamous cell carcinomas, 2 adenocarcinomas, 2 poorly differentiated carcinomas, 1 carcinoma ex pleomorphic adenoma, 1 salivary duct carcinoma, 1 lymphoepithelial carcinoma).
  • CONCLUSION: This study shows that FDG PET has a significant impact on the management of patients with salivary malignant tumors in both the initial staging and restaging.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Neoplasm Staging / methods. Prognosis. Radiopharmaceuticals. Reproducibility of Results. Sensitivity and Specificity

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  • (PMID = 16444995.001).
  • [ISSN] 0914-7187
  • [Journal-full-title] Annals of nuclear medicine
  • [ISO-abbreviation] Ann Nucl Med
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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71. Gaissert HA, Grillo HC, Shadmehr MB, Wright CD, Gokhale M, Wain JC, Mathisen DJ: Uncommon primary tracheal tumors. Ann Thorac Surg; 2006 Jul;82(1):268-72; discussion 272-3
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  • BACKGROUND: Primary tracheal tumors other than adenoid cystic or squamous cell carcinoma are uncommon and have a heterogeneous histologic appearance.
  • METHODS: A retrospective analysis was performed of uncommon tracheal tumors among 360 primary tracheal tumors seen over 40 years, excluding adenoid cystic and squamous cell carcinoma.
  • RESULTS: Of 90 patients, 34 (38%) had benign tumors and 56 malignant: 11 carcinoid tumors, 14 mucoepidermoid carcinomas, 13 sarcomas, 15 nonsquamous bronchogenic carcinomas, 2 lymphomas, and 1 melanoma.
  • Dyspnea was the most common symptom in benign tumors and hemoptysis in malignant tumors.
  • After resection, survival at 10 years was 94% for benign and 83% for carcinoid tumors, and at 5 years survival was 60% for bronchogenic carcinoma, 100% for mucoepidermoid tumors, and 78% for sarcomas.
  • CONCLUSIONS: Surgical resection of uncommon primary tracheal tumors alleviates airway obstruction, is curative in patients with benign or slow-growing malignant lesions, and prolongs survival in highly malignant lesions.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Bronchi / surgery. Bronchoscopy. Child. Child, Preschool. Combined Modality Therapy. Female. Follow-Up Studies. Hospital Mortality. Humans. Laryngeal Neoplasms / epidemiology. Laryngeal Neoplasms / pathology. Laryngeal Neoplasms / surgery. Laryngectomy. Life Tables. Male. Middle Aged. Neoplasm Metastasis. Neoplasm Recurrence, Local / epidemiology. Postoperative Complications / epidemiology. Radiotherapy, Adjuvant. Reoperation. Retrospective Studies. Survival Analysis

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  • (PMID = 16798228.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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72. Sung A, Bergsneider M, Wang MB: Transnasal endoscopic surgery of the cavernous sinus for tissue diagnosis. Laryngoscope; 2010 Feb;120(2):282-4
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  • [Title] Transnasal endoscopic surgery of the cavernous sinus for tissue diagnosis.
  • [MeSH-minor] Aged. Carcinoma, Adenoid Cystic / pathology. Carcinoma, Adenoid Cystic / secondary. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / secondary. Female. Humans. Male


73. Chen AM, Garcia J, Lee NY, Bucci MK, Eisele DW: Patterns of nodal relapse after surgery and postoperative radiation therapy for carcinomas of the major and minor salivary glands: what is the role of elective neck irradiation? Int J Radiat Oncol Biol Phys; 2007 Mar 15;67(4):988-94
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  • Histology was: adenoid cystic (84 patients), mucoepidermoid (60 patients), adenocarcinoma (58 patients), acinic cell (21 patients), undifferentiated (11 patients), carcinoma ex pleomorphic adenoma (7 patients), squamous cell (7 patients), and salivary duct carcinoma (3 patients); 131 patients (52%) had ENI.
  • The highest crude rates of nodal relapse among those treated without ENI were found in patients with squamous cell carcinoma (67%), undifferentiated carcinoma (50%), adenocarcinoma (34%), and mucoepidermoid carcinoma (29%).
  • There were no nodal failures observed among patients with adenoid cystic or acinic cell histology.
  • [MeSH-major] Carcinoma / secondary. Lymphatic Irradiation. Salivary Gland Neoplasms / pathology. Salivary Glands, Minor / pathology

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  • (PMID = 17234357.001).
  • [ISSN] 0360-3016
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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74. Lü BJ, Zhu J, Gao L, Xie L, Xu JY, Lai MD: [Diagnostic accuracy and pitfalls in fine needle aspiration cytology of salivary glands: a study of 113 cases]. Zhonghua Bing Li Xue Za Zhi; 2005 Nov;34(11):706-10
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  • RESULTS: The FNAC diagnostic failure (2); non-neoplastic lesions (12); benign neoplasm (82) and malignant neoplasm (17).
  • Cytologically, the distinction between cellular pleomorphic adenoma, adenoid cystic carcinoma and basal cell adenoma could be difficult due to their overlapping morphologic features.
  • The cytologic patterns of primary lymphoepithelial carcinoma of the parotid were indistinguishable from those of metastatic nasopharyngeal undifferentiated carcinoma.
  • The three inaccurately diagnosed cases of FNAC are, as follows: reactive lymphoid hyperplasia of lymph node mistaken as non-Hodgkin lymphoma, mucoepidermoid carcinoma diagnosed as "scanty atypical cells present" and primary lymphoepithelial carcinoma mistaken as benign lymphoepithelial lesion.
  • On the basis of FNAC, 97.4% (110 /113) were correctly depicted as benign (95/96; 99.0%) or malignant (15/17; 88.2%).
  • Furthermore, 90.3% (102 /113) (specificity = 91.9%; 102/111) were accurately diagnosed, including 91.7% (88/96) benign lesions (specificity = 92.6% ; 88/95) and 82.4% (14/17) malignant tumors (specificity = 87.5%; 14/16).
  • CONCLUSIONS: FNAC is reliable in distinguishing benign and malignant salivary gland lesions.
  • A specific cytologic diagnosis is often possible.
  • On the other hand, due to the pitfalls in cytologic diagnosis of certain salivary gland tumors, tissue biopsy for histologic examination may be necessary.
  • [MeSH-major] Carcinoma, Mucoepidermoid / pathology. Carcinoma, Squamous Cell / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands / pathology
  • [MeSH-minor] Adenolymphoma / pathology. Adenoma / pathology. Adenoma, Pleomorphic / pathology. Adolescent. Adult. Aged. Biopsy, Fine-Needle. Carcinoma, Adenoid Cystic / pathology. Child. Diagnosis, Differential. Diagnostic Errors. Female. Humans. Male. Middle Aged. Parotid Neoplasms / pathology. Retrospective Studies. Submandibular Gland Neoplasms / pathology

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  • (PMID = 16536312.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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75. Carrillo JF, Celis MA, Ramirez-Ortega M, Rivas B, Ochoa FJ: Osteoplastic maxillotomy for treatment of neoplasms of the nasopharynx and infratemporal fossa. Ann Otol Rhinol Laryngol; 2005 Jan;114(1 Pt 1):58-64
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  • Ten patients underwent osteoplastic maxillotomy, 3 of whom had a diagnosis of malignancy, and 7 of whom had nasopharyngeal angiofibromas (NPAs).
  • Resection of malignant lesions with good results is feasible.
  • [MeSH-minor] Adolescent. Adult. Aged. Angiofibroma / surgery. Carcinoma, Adenoid Cystic / surgery. Carcinoma, Squamous Cell / surgery. Craniotomy. Esthetics. Female. Hemangiopericytoma / surgery. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / surgery. Quality of Life. Treatment Outcome. Zygoma / surgery

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  • (PMID = 15697164.001).
  • [ISSN] 0003-4894
  • [Journal-full-title] The Annals of otology, rhinology, and laryngology
  • [ISO-abbreviation] Ann. Otol. Rhinol. Laryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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76. Madani I, Bonte K, Vakaet L, Boterberg T, De Neve W: Intensity-modulated radiotherapy for sinonasal tumors: Ghent University Hospital update. Int J Radiat Oncol Biol Phys; 2009 Feb 1;73(2):424-32
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  • The tumor histologic type was adenocarcinoma in 54, squamous cell carcinoma in 17, esthesioneuroblastoma in 9, and adenoid cystic carcinoma in 4.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Disease-Free Survival. Female. Follow-Up Studies. Hospitals, University. Humans. Male. Middle Aged. Multivariate Analysis. Neoplasm Recurrence, Local / mortality. Neoplasm Recurrence, Local / radiotherapy. Radiotherapy Dosage. Survival Rate. Treatment Outcome

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  • (PMID = 18755554.001).
  • [ISSN] 1879-355X
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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77. Boukheris H, Curtis RE, Land CE, Dores GM: Incidence of carcinoma of the major salivary glands according to the WHO classification, 1992 to 2006: a population-based study in the United States. Cancer Epidemiol Biomarkers Prev; 2009 Nov;18(11):2899-906
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  • [Title] Incidence of carcinoma of the major salivary glands according to the WHO classification, 1992 to 2006: a population-based study in the United States.
  • Squamous cell (IR, 3.44) and mucoepidermoid (IR, 3.23) carcinomas occurred most frequently among males, whereas mucoepidermoid (IR, 2.67), acinic cell (IR, 1.57), and adenoid cystic (IR, 1.40) carcinomas were most common among females.
  • Mucoepidermoid, acinic cell, and adenoid cystic carcinomas predominated in females through age approximately 50 years; thereafter, IRs of acinic cell and adenoid cystic carcinomas were nearly equal among females and males, whereas IRs of mucoepidermoid carcinoma among males exceeded IRs among females (IRR, 1.57; 95% CI, 1.38-1.78).
  • Except for mucoepidermoid and adenoid cystic carcinomas, which occurred equally among all races, other subtypes had significantly lower incidence among Blacks and Asians/Pacific Islanders than among Whites.
  • Adenoid cystic carcinoma occurred equally in the submandibular and parotid glands, and other M-SGC histologic subtypes evaluated had 77% to 98% lower IRs in the submandibular gland.
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Incidence. Male. Middle Aged. Neoplasm Staging. Prognosis. Risk Factors. SEER Program. United States / epidemiology. World Health Organization. Young Adult

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  • (PMID = 19861510.001).
  • [ISSN] 1538-7755
  • [Journal-full-title] Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
  • [ISO-abbreviation] Cancer Epidemiol. Biomarkers Prev.
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / / Z01 CP010183-05
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS144622; NLM/ PMC2779732
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78. Marchetti C, Bianchi A, Mazzoni S, Cipriani R, Campobassi A: Oromandibular reconstruction using a fibula osteocutaneous free flap: four different "preplating" techniques. Plast Reconstr Surg; 2006 Sep;118(3):643-51
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  • [MeSH-major] Carcinoma, Squamous Cell / surgery. Fibula / transplantation. Jaw Fixation Techniques / instrumentation. Mandibular Neoplasms / surgery. Mouth Neoplasms / surgery. Reconstructive Surgical Procedures. Surgical Flaps
  • [MeSH-minor] Adolescent. Adult. Bone Plates. Bone Screws. Carcinoma, Adenoid Cystic / surgery. Cephalometry. Esthetics. Fibrosarcoma / surgery. Humans. Lymphoma, Non-Hodgkin / surgery. Male. Mandibular Diseases / surgery. Middle Aged. Neoplasm Invasiveness. Osteitis / surgery. Osteosarcoma / surgery. Osteotomy. Transplantation, Heterotopic

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  • (PMID = 16932172.001).
  • [ISSN] 1529-4242
  • [Journal-full-title] Plastic and reconstructive surgery
  • [ISO-abbreviation] Plast. Reconstr. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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79. Agarwal JP, Jain S, Gupta T, Tiwari M, Laskar SG, Dinshaw KA, Chaturvedi P, D'cruz AK, Shrivastava SK: Intraoral adenoid cystic carcinoma: prognostic factors and outcome. Oral Oncol; 2008 Oct;44(10):986-93
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  • [Title] Intraoral adenoid cystic carcinoma: prognostic factors and outcome.
  • Intraoral (oral cavity and oropharynx) adenoid cystic carcinomas are uncommon cancers characterized by slow evolution, protracted clinical course, multiple and/or delayed recurrences, and late distant metastases.
  • To analyze and correlate prognostic factors with outcome in intraoral adenoid cystic carcinoma.
  • Medical records of 76 patients with intraoral adenoid cystic carcinoma treated with definitive loco-regional therapy at the institute between 1992 and 2004 were retrospectively reviewed and analyzed.Majority (85.5%) of the patients had advanced stage disease.
  • Intraoral adenoid cystic carcinoma is an uncommon disease with an enigmatic clinical course.
  • Larger prospective studies with mature follow-up are needed to define the optimal treatment of intraoral adenoid cystic carcinoma.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Carcinoma, Squamous Cell / pathology. Mouth Neoplasms / pathology
  • [MeSH-minor] Adult. Disease-Free Survival. Female. Humans. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Recurrence, Local. Prognosis. Retrospective Studies. Treatment Outcome. Young Adult

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  • (PMID = 18329324.001).
  • [ISSN] 1879-0593
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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80. Kakudo N, Ogawa Y, Suzuki K, Kushida S, Kusumoto K: Clinical outcome of surgical treatment for periorbital basal cell carcinoma. Ann Plast Surg; 2009 Nov;63(5):531-5
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  • [Title] Clinical outcome of surgical treatment for periorbital basal cell carcinoma.
  • Basal cell carcinoma (BCC) has a predilection for the periorbital region, which is a special, prominent, cosmetic, functional area to protect the eyeball.
  • For squamous cell carcinoma and melanoma, extensive resection with reconstruction is performed.
  • The histologic classifications were solid (80%), morphea (7%), mix (7%), superficial (2%), keratotic (2%), and adenoid (2%).
  • [MeSH-major] Carcinoma, Basal Cell / surgery. Eyelid Neoplasms / surgery. Surgical Flaps

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  • (PMID = 19801921.001).
  • [ISSN] 1536-3708
  • [Journal-full-title] Annals of plastic surgery
  • [ISO-abbreviation] Ann Plast Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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81. Lin Z, Liu M, Li Z, Kim C, Lee E, Kim I: DeltaNp63 protein expression in uterine cervical and endometrial cancers. J Cancer Res Clin Oncol; 2006 Dec;132(12):811-6
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  • MATERIALS AND METHODS: DeltaNp63 protein expression was studied in a variety of 127 cases of uterine cervical lesions (20 non-neoplastic cervices, 43 cervical intraepithelial neoplasia [CIN], 54 squamous cell carcinomas (SCCs), 40 adenocarcinomas, and 13 other histologic types) and 30 endometrioid type of endometrial adenocarcinomas by using immunohistochemistry.
  • One SCC cell line (ME-180) and one adenocarcinoma cell line (HeLa) were also included.
  • RESULTS: In uterine cervix, the expression of DeltaNp63 was increased with progression of CIN, and positive in all SCCs, transitional cell carcinomas, and adenoid basal carcinoma, but negative in all adenocarcinomas.
  • Adenosquamous cell carcinoma and mixed neuroendocrine and squamous cell carcinoma were positive in squamous component, but not in adenocarcinoma and neuroendocrine carcinoma components.
  • ME-180 cell line was positive, whereas HeLa cell line was negative.
  • Endometrioid type of endometrial adenocarcinomas showed a positive staining in glandular (26.7%) and squamous component.
  • CONCLUSIONS: Immunohistochemical staining for DeltaNp63 is a powerful marker for squamous differentiation and useful in exclusion of glandular and neuroendocrine differentiation in uterine cervical cancers, but not always in endometrial cancers.
  • [MeSH-major] Adenocarcinoma / metabolism. Carcinoma, Squamous Cell / metabolism. DNA-Binding Proteins / biosynthesis. Endometrial Neoplasms / metabolism. Trans-Activators / biosynthesis. Tumor Suppressor Proteins / biosynthesis. Uterine Cervical Neoplasms / metabolism
  • [MeSH-minor] Antigens, Differentiation / biosynthesis. Cell Line, Tumor. Cervix Uteri / cytology. Cervix Uteri / metabolism. Female. HeLa Cells. Humans. Immunohistochemistry. Transcription Factors

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  • (PMID = 16804722.001).
  • [ISSN] 0171-5216
  • [Journal-full-title] Journal of cancer research and clinical oncology
  • [ISO-abbreviation] J. Cancer Res. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antigens, Differentiation; 0 / DNA-Binding Proteins; 0 / TP63 protein, human; 0 / Trans-Activators; 0 / Transcription Factors; 0 / Tumor Suppressor Proteins
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82. Ariyoshi Y, Shimahara M, Omura K, Yamamoto E, Mizuki H, Chiba H, Imai Y, Fujita S, Shinohara M, Seto K, Japanese Society of Oral and Maxillofacial Surgeons, 2002: Epidemiological study of malignant tumors in the oral and maxillofacial region: survey of member institutions of the Japanese Society of Oral and Maxillofacial Surgeons, 2002. Int J Clin Oncol; 2008 Jun;13(3):220-8
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  • [Title] Epidemiological study of malignant tumors in the oral and maxillofacial region: survey of member institutions of the Japanese Society of Oral and Maxillofacial Surgeons, 2002.
  • On histopathological examinations, squamous cell carcinoma (88.7%) was the most common type found, followed by adenoid cystic carcinoma (2.1%), and mucoepidermoid carcinoma (1.7%).
  • Nonepithelial tumors, among which malignant melanoma was the most common type, accounted for 1.8% of the tumors.
  • The sizes of the nonepithelial malignant tumors ranged from 1.0 to 7.0 cm, with an average size of 3.7 cm.

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  • (PMID = 18553231.001).
  • [ISSN] 1341-9625
  • [Journal-full-title] International journal of clinical oncology
  • [ISO-abbreviation] Int. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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83. Teramoto N, Nishimura R, Saeki T, Nogawa T, Hiura M: Adenoid basal carcinoma of the uterine cervix: report of two cases with reference to adenosquamous carcinoma. Pathol Int; 2005 Jul;55(7):445-52
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  • [Title] Adenoid basal carcinoma of the uterine cervix: report of two cases with reference to adenosquamous carcinoma.
  • Adenoid basal carcinoma (ABC) of the uterine cervix is a rare neoplasm with excellent prognosis.
  • Differential diagnosis between ABC and an ABC-like lesion of adenosquamous cell carcinoma (ASC) of the cervix is important due to their contrasting prognosis.
  • The two ABC were incidentally found in the uterine cervix of 69-year-old and 59-year-old Japanese women due to cervical intraepithelial neoplasia grade 3 and to squamous cell carcinoma, respectively.
  • An ABC-like lesion was defined as basaloid cell nests simulating ABC, but with some features indicating malignant potential.
  • However, the differential diagnosis was sometimes difficult because two of seven ABC-like lesions were originally diagnosed as ABC.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Carcinoma, Adenosquamous / pathology. Carcinoma, Basal Cell / pathology. Uterine Cervical Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Keratin-7. Keratin-8. Keratins / analysis. Ki-67 Antigen / analysis. Middle Aged

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  • (PMID = 15982222.001).
  • [ISSN] 1320-5463
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / KRT7 protein, human; 0 / KRT8 protein, human; 0 / Keratin-7; 0 / Keratin-8; 0 / Ki-67 Antigen; 68238-35-7 / Keratins
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84. Iannetti G, Valentini V, Rinna C, Ventucci E, Marianetti TM: Ethmoido-orbital tumors: our experience. J Craniofac Surg; 2005 Nov;16(6):1085-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adenocarcinoma / surgery. Adult. Aged. Carcinoma, Adenoid Cystic / surgery. Carcinoma, Squamous Cell / surgery. Female. Humans. Male. Maxillary Sinus Neoplasms / pathology. Maxillary Sinus Neoplasms / surgery. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging. Nose Neoplasms / pathology. Orbit Evisceration. Radiotherapy, Adjuvant. Retrospective Studies. Sphenoid Sinus / pathology. Survival Rate

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  • (PMID = 16327559.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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85. Du X, Yin X, Zhou N, Zhang G, Shi H, Cao S: Extramammary Paget's disease mimicking acantholytic squamous cell carcinoma in situ: a case report. J Cutan Pathol; 2010 Jun;37(6):683-6
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  • [Title] Extramammary Paget's disease mimicking acantholytic squamous cell carcinoma in situ: a case report.
  • BACKGROUND: Extramammary Paget's disease (EMPD) is an uncommon skin neoplasm characterized by Paget's cells with pale-staining cytoplasm in the epidermis, and cases with distinguished acantholysis but lacking characteristic Paget's cells were rarely reported in the literature.
  • METHODS: An 80-year-old male with lesion on scrotum was screened histologically and immunohistologically for the diagnosis of his tumor.
  • RESULTS: Histological examination showed acanthosis with cellular atypia and focal acantholysis, consistent with acantholytic squamous cell carcinoma in situ (SCCIS).
  • CONCLUSIONS: These findings strongly indicated the diagnosis of EMPD mimicking acantholytic SCCIS.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Genital Neoplasms, Male / pathology. Paget Disease, Extramammary / pathology. Scrotum / pathology
  • [MeSH-minor] Aged, 80 and over. Diagnosis, Differential. Humans. Immunohistochemistry. Male

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  • (PMID = 19615013.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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86. Chang SM, Xing RD, Zhang FM, Duan YQ: Serum soluble CD44v6 levels in patients with oral and maxillofacial malignancy. Oral Dis; 2009 Nov;15(8):570-2
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  • OBJECTIVE: To determine the levels of serum sCD44v6 in patients with oral cancer and evaluate the value of serum sCD44v6 in adjuvant diagnosis, staging and monitoring treatment response in these patients.
  • One week after treatment, venous blood was collected once again in 60 patients with oral and maxillofacial squamous cell carcinoma (OSCC).
  • The levels of serum sCD44v6 in patients with OSCC and salivary carcinoma showed no difference with those in control group (P > 0.05).
  • CONCLUSION: The possible roles of CD44v6 in the diagnosis of oral and maxillofacial malignancy deserve further elucidation and evaluation.
  • [MeSH-major] Antigens, CD44 / blood. Biomarkers, Tumor / blood. Carcinoma, Squamous Cell / blood. Head and Neck Neoplasms / blood. Mouth Neoplasms / blood
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Carcinoma, Adenoid Cystic / blood. Carcinoma, Adenoid Cystic / drug therapy. Carcinoma, Adenoid Cystic / surgery. Carcinoma, Mucoepidermoid / blood. Carcinoma, Mucoepidermoid / drug therapy. Carcinoma, Mucoepidermoid / surgery. Case-Control Studies. Female. Humans. Male. Middle Aged. Neoplasm Staging. Reference Values. Salivary Gland Neoplasms / blood. Salivary Gland Neoplasms / drug therapy. Salivary Gland Neoplasms / surgery. Treatment Outcome

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  • (PMID = 19563418.001).
  • [ISSN] 1601-0825
  • [Journal-full-title] Oral diseases
  • [ISO-abbreviation] Oral Dis
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD44; 0 / Biomarkers, Tumor; 0 / CD44v6 antigen
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87. Daly ME, Chen AM, Bucci MK, El-Sayed I, Xia P, Kaplan MJ, Eisele DW: Intensity-modulated radiation therapy for malignancies of the nasal cavity and paranasal sinuses. Int J Radiat Oncol Biol Phys; 2007 Jan 1;67(1):151-7
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  • Histology was: 12 squamous cell, 7 esthesioneuroblastoma, 5 adenoid cystic, 5 undifferentiated, 5 adenocarcinoma, and 2 other.
  • [MeSH-minor] Adenocarcinoma / radiotherapy. Adenocarcinoma / secondary. Adult. Aged. Aged, 80 and over. Carcinoma, Adenoid Cystic / radiotherapy. Carcinoma, Adenoid Cystic / secondary. Carcinoma, Squamous Cell / radiotherapy. Carcinoma, Squamous Cell / secondary. Esthesioneuroblastoma, Olfactory / radiotherapy. Esthesioneuroblastoma, Olfactory / secondary. Female. Humans. Male. Middle Aged. Nasal Cavity. Neoplasm Staging. Radiation Injuries / etiology. Radiotherapy Dosage

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  • (PMID = 17189068.001).
  • [ISSN] 0360-3016
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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88. Vasudev P, Boutross-Tadross O, Radhi J: Basaloid squamous cell carcinoma: two case reports. Cases J; 2009;2:9351
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  • [Title] Basaloid squamous cell carcinoma: two case reports.
  • Basaloid squamous cell carcinoma (BSCC) is a rare and aggressive variant of squamous cell carcinoma (SCC) that occurs preferentially in the upper aerodigestive tract.
  • BSCC of the head and neck should be distinguished from adenoid cystic carcinoma, small cell neuroendocrine carcinoma, basal cell adenocarcinoma, adenosquamous carcinoma, squamous cell carcinoma, spindle cell squamous carcinoma, mucoepidermoid carcinoma, and adenoid cystic carcinoma.

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  • [Cites] Eur J Cancer. 2008 Jan;44(2):244-50 [18096379.001]
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  • (PMID = 20062602.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2804002
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89. Shang ZJ, Liu K, Chen XM: [Expression of chemokine receptor-7 in oral squamous cell carcinoma and its relation to cervical lymph node metastasis]. Zhonghua Kou Qiang Yi Xue Za Zhi; 2008 Oct;43(10):592-6
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  • [Title] [Expression of chemokine receptor-7 in oral squamous cell carcinoma and its relation to cervical lymph node metastasis].
  • OBJECTIVE: To investigate the expression of chemokine receptor CCR7 in oral squamous cell carcinoma (OSCC) and its possible role in directional neck lymph node metastasis.
  • METHODS: The expression of chemokine receptor CCR7 was examined in 85 cases of OSCC, normal oral mucosa, and Tca8113 and adenoid cystic carcinoma (ACC-M) cell lines using immunohistochemistry, RT-PCR and Western blotting.
  • CONCLUSIONS: CCR7 may play an important role in the development and lymph node metastasis of oral squamous cell carcinoma.
  • [MeSH-major] Carcinoma, Squamous Cell / metabolism. Mouth Neoplasms / metabolism. Receptors, CCR7 / metabolism

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  • (PMID = 19087620.001).
  • [ISSN] 1002-0098
  • [Journal-full-title] Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
  • [ISO-abbreviation] Zhonghua Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / CCR7 protein, human; 0 / Receptors, CCR7
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90. Puizina-Ivić N, Sapunar D, Marasović D, Mirić L: An overview of Bcl-2 expression in histopathological variants of basal cell carcinoma, squamous cell carcinoma, actinic keratosis and seborrheic keratosis. Coll Antropol; 2008 Oct;32 Suppl 2:61-5
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  • [Title] An overview of Bcl-2 expression in histopathological variants of basal cell carcinoma, squamous cell carcinoma, actinic keratosis and seborrheic keratosis.
  • The Bcl-2 protein has been shown to suppress cell death and protects cell against apoptosis induced by different death-inducing signals.
  • In this study the authors have analyzed imunohistochemically the expression of Bcl-2 protein in the histopathological variants of the most common malignant tumors of the skin--basal cell carcinoma (BCC) and squamous cell tumor (SCC), as well as in the precancerous lesion actinic keratosis (AK) and in benign tumor seborrheic keratosis (SK).
  • Bcl-2 expression in solid, adenoid and cystic variants of BCC exhibited immunoreactivity of tumor stroma with more intense staining among peripheral palisading cells.
  • Among SCC in all samples, tumor tissue lack to express Bcl-2 positivity.
  • In cases of hypertrophic and atrophic variants of AK, Bcl-2 expression was confined to basal cell layer, as well as in one case of hypertrophic variant in suprabasal cells.
  • In three histological variants of SK expresseion of Bcl-2 protein was in areas of basaloid proliferation, while in areas of squamous differentiation was negative.
  • In clonal variant immunostaining was positive among cells in characteristic "nests" Distribution of Bcl-2 protein expression in solid, adenoid and cystic variant of BCC showed that peripheral proliferating cells are protected against apoptosis what permits tumor growth.
  • In morpheaform variant reduced amount of Bcl-2 expression indicated that this variant of BCC has increased cell proliferation, and in practice shows tendency for recurrence and difficulties to eradicate.
  • In SCC, lack of Bcl-2 expression indicates that origin of tumor cells is from more differentiated suprabasal keratinocytes.
  • [MeSH-major] Carcinoma, Basal Cell / metabolism. Carcinoma, Squamous Cell / metabolism. Keratosis, Actinic / metabolism. Keratosis, Seborrheic / metabolism. Proto-Oncogene Proteins c-bcl-2 / metabolism. Skin Neoplasms / metabolism


91. Boo H, Hogg JP: Nasal cavity neoplasms: a pictorial review. Curr Probl Diagn Radiol; 2010 Mar-Apr;39(2):54-61
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  • Examples include squamous cell cancer, adenoid cystic cancer, esthesioneuroblastoma, inverted papilloma, juvenile nasal angiofibroma, melanoma, lymphoma, sarcoma, and benign nasal histiocytoma.
  • [MeSH-major] Nasal Cavity. Nose Neoplasms / diagnosis
  • [MeSH-minor] Angiofibroma / diagnosis. Carcinoma, Adenoid Cystic / diagnosis. Carcinoma, Squamous Cell / diagnosis. Chondrosarcoma / diagnosis. Diagnosis, Differential. Esthesioneuroblastoma, Olfactory / diagnosis. Histiocytoma, Benign Fibrous / diagnosis. Humans. Magnetic Resonance Imaging. Melanoma / diagnosis. Papilloma, Inverted / diagnosis. Positron-Emission Tomography. Tomography, X-Ray Computed

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  • [Copyright] Copyright (c) 2010 Mosby, Inc. All rights reserved.
  • (PMID = 20113866.001).
  • [ISSN] 1535-6302
  • [Journal-full-title] Current problems in diagnostic radiology
  • [ISO-abbreviation] Curr Probl Diagn Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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92. Muller A, Sonkoly E, Eulert C, Gerber PA, Kubitza R, Schirlau K, Franken-Kunkel P, Poremba C, Snyderman C, Klotz LO, Ruzicka T, Bier H, Zlotnik A, Whiteside TL, Homey B, Hoffmann TK: Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy. Int J Cancer; 2006 May 1;118(9):2147-57
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  • While squamous cell carcinomas (SCC) are characterized by lymphogenous spread, adenoid cystic carcinomas (ACC) disseminate preferentially hematogenously.
  • To study cellular and molecular mechanisms of organ-specific metastasis, we used SCC and ACC cell lines and tumor tissues, obtained from patients with primary or metastatic disease.
  • Comprehensive analysis at the mRNA and protein level of human chemokine receptors showed that SCC and ACC cells exhibited distinct and nonrandom expression profiles for these receptors.
  • SCC predominantly expressed receptors for chemokines homeostatically expressed in lymph nodes, including CC chemokine receptor (CCR) 7 and CXC chemokine receptor (CXCR)5.
  • No difference in expression of chemokine receptors was seen in primary SCC and corresponding lymph node metastases.
  • In contrast to SCC, ACC cells primarily expressed CXCR4.
  • Exposure of ACC cells to cisplatin resulted in upregulation of CXCR4 on the cell surface, which was repressed by the transcriptional inhibitor, alpha-amanitin.
  • Furthermore, CXCL12 suppressed the rate of apoptosis induced by cisplatin in ACC cells, suggesting that signaling via CXCR4 may be part of a tumor cell survival program.
  • Discrimination of the chemokine receptor profile in SCC and ACC in vitro and in tissues provided insights into their distinct biologic and clinical characteristics as well as indications that chemokine receptors might serve as future therapeutic targets in these malignancies.
  • [MeSH-major] Antineoplastic Agents / pharmacology. Carcinoma, Adenoid Cystic / secondary. Carcinoma, Squamous Cell / secondary. Cisplatin / pharmacology. Head and Neck Neoplasms / drug therapy. Head and Neck Neoplasms / pathology. Receptors, Chemokine / analysis
  • [MeSH-minor] Apoptosis. Cell Survival. Gene Expression Profiling. Humans. Neoplasm Metastasis. RNA, Messenger / analysis. Signal Transduction


93. Ozer E, Bapna S, Agrawal A, Schuller DE: Maxillary removal and reinsertion: a favorable approach for extensive anterior cranial base tumors. Otolaryngol Head Neck Surg; 2010 Mar;142(3):322-6
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  • Sixty-two (80%) patients had malignant lesions.
  • The most commonly encountered malignant neoplasm was squamous cell cancer (40.3%), followed by esthesioneuroblastoma (24.1%), adenoid cystic cancer (8%), and other neoplasms (27.4%).
  • Overall five-year survival for the patients with squamous cell carcinoma was 62 percent.
  • [MeSH-major] Carcinoma, Squamous Cell / surgery. Cranial Fossa, Anterior. Otorhinolaryngologic Surgical Procedures / methods. Skull Base Neoplasms / surgery

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  • [Copyright] Copyright 2010 American Academy of Otolaryngology-Head and Neck Surgery Foundation. Published by Mosby, Inc. All rights reserved.
  • (PMID = 20172374.001).
  • [ISSN] 1097-6817
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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94. Kerawala CJ: Acantholytic squamous cell carcinoma of the oral cavity: a more aggressive entity? Br J Oral Maxillofac Surg; 2009 Mar;47(2):123-5
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  • [Title] Acantholytic squamous cell carcinoma of the oral cavity: a more aggressive entity?
  • Acantholytic squamous cell carcinoma is a histologically distinct variant of squamous cell carcinoma that arises most commonly in areas of the skin exposed to the sun.
  • It is rare on mucosal surfaces of the upper aerodigestive tract, where there is some suggestion that it might behave more aggressively than conventional squamous cell carcinoma.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Tongue Neoplasms / pathology
  • [MeSH-minor] Acantholysis. Fatal Outcome. Humans. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging

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  • (PMID = 18565630.001).
  • [ISSN] 1532-1940
  • [Journal-full-title] The British journal of oral & maxillofacial surgery
  • [ISO-abbreviation] Br J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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95. Hu WH, Xie FY, Fang SH, Jiao JJ, Yan C, Peng WJ, Fu XY, Zhang F: [Cancer of the nasal cavity]. Zhonghua Zhong Liu Za Zhi; 2005 Feb;27(2):117-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To analyze the factors affecting prognosis of patients with nasal carcinoma.
  • The 5-year survival rate was 55.8% in squamous-cell carcinoma, 44.0% in adenocarcinoma, 59.7% in undifferentiated carcinoma, 76.3% in adenoid cystic carcinoma, 71.4% in mucoepidermoid carcinoma, 25.0% in rhabdomyosarcoma, 26.7% in malignant melanoma, 50.0% in neuroblastoma (P > 0.05).
  • CONCLUSION: Clinical stage, immediate therapeutic response and involvement of sphenoidal or maxillary sinus; but not the pathologic type, the presence of cervical metastasis nor the method of treatment, are the factors affecting the prognosis of patients with nasal carcinoma.

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  • (PMID = 15946555.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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96. Honings J, Gaissert HA, van der Heijden HF, Verhagen AF, Kaanders JH, Marres HA: Clinical aspects and treatment of primary tracheal malignancies. Acta Otolaryngol; 2010 Jul;130(7):763-72
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  • OBJECTIVE: Primary tracheal tumors pose a diagnostic and therapeutic challenge for the physician when confronted with this mostly malignant tumor.
  • Diagnosis is often delayed for months or years due to its aspecific and asthma-mimicking symptoms.
  • The available literature on the diagnosis and management of this group of tumors is reviewed to summarize the available knowledge about these uncommon tumors.
  • [MeSH-major] Tracheal Neoplasms / diagnosis. Tracheal Neoplasms / therapy
  • [MeSH-minor] Airway Obstruction / etiology. Airway Obstruction / therapy. Algorithms. Bronchoscopy. Carcinoma, Adenoid Cystic / diagnosis. Carcinoma, Adenoid Cystic / epidemiology. Carcinoma, Adenoid Cystic / therapy. Carcinoma, Squamous Cell / diagnosis. Carcinoma, Squamous Cell / epidemiology. Carcinoma, Squamous Cell / therapy. Cough / etiology. Diagnostic Imaging. Dyspnea / etiology. Hemoptysis / etiology. Humans. Neoplasm Staging. Respiratory Function Tests. Respiratory Sounds / etiology. Survival Rate. Trachea / surgery

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  • (PMID = 20569185.001).
  • [ISSN] 1651-2251
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
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97. Moore MG, Lin DT, Mikulec AA, McKenna MJ, Varvares MA: The occipital flap for reconstruction after lateral temporal bone resection. Arch Otolaryngol Head Neck Surg; 2008 Jun;134(6):587-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Aged. Aged, 80 and over. Carcinoma, Adenoid Cystic / surgery. Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / surgery. Ear Auricle / surgery. Female. Humans. Male. Middle Aged. Retrospective Studies

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  • (PMID = 18559723.001).
  • [ISSN] 1538-361X
  • [Journal-full-title] Archives of otolaryngology--head & neck surgery
  • [ISO-abbreviation] Arch. Otolaryngol. Head Neck Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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98. Prasad KK, Kaur S: Acantholytic squamous cell carcinoma of the oral cavity: an uncommon histological variant of squamous cell carcinoma. Minerva Stomatol; 2010 Jun;59(6):377-80
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  • [Title] Acantholytic squamous cell carcinoma of the oral cavity: an uncommon histological variant of squamous cell carcinoma.
  • Acantholytic squamous cell carcinoma is a rare and aggressive histological variant of squamous cell carcinoma, characterized by tubular and alveolar patterns as a consequence of the acantholysis.
  • We report a case of acantholytic squamous cell carcinoma in a 70-year-old woman, who was admitted to our institution for the progressively enlarging exophytic and ulcerated lesion.
  • We report this interesting lesion due to the rarity of acantholytic variant of squamous cell carcinoma and the literature is briefly reviewed.
  • [MeSH-major] Carcinoma, Squamous Cell / prevention & control. Mouth Neoplasms / pathology


99. Buchmann L, Larsen C, Pollack A, Tawfik O, Sykes K, Hoover LA: Endoscopic techniques in resection of anterior skull base/paranasal sinus malignancies. Laryngoscope; 2006 Oct;116(10):1749-54
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  • The most common diagnosis was squamous cell carcinoma occurring in 33% of the cases.
  • The remaining pathologies included esthesioneuroblastoma (23%), adenoid cystic carcinoma (15%), melanoma (3%), sinonasal undifferentiated carcinoma (3%), lymphoma (5%), nasopharyngeal carcinoma (4%), and other tumor types (14%).
  • [MeSH-minor] Carcinoma / surgery. Carcinoma, Adenoid Cystic / surgery. Carcinoma, Squamous Cell / surgery. Disease-Free Survival. Esthesioneuroblastoma, Olfactory / surgery. Esthetics. Female. Follow-Up Studies. Humans. Lymphoma / surgery. Male. Maxilla / surgery. Melanoma / surgery. Middle Aged. Nasopharyngeal Neoplasms / surgery. Neoadjuvant Therapy. Neoplasm Recurrence, Local / therapy. Retrospective Studies. Survival Rate

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  • (PMID = 17003718.001).
  • [ISSN] 0023-852X
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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100. Zhang JP, Li CY: [The effect of transforming growth factor-beta1 on EDA region of fibronectin in oral squamous cell carcinoma and adenoid cystic carcinoma cells]. Zhonghua Kou Qiang Yi Xue Za Zhi; 2007 Jan;42(1):47-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The effect of transforming growth factor-beta1 on EDA region of fibronectin in oral squamous cell carcinoma and adenoid cystic carcinoma cells].
  • OBJECTIVE: To investigate the effect of transforming growth factor-beta1 (TGF-beta1) on EDA region of fibronectin in oral squamous cell carcinoma and adenoid cystic carcinoma cells.
  • In the three oral carcinoma cells, the expression of EDA(+) mRNAs in the group with TGF-beta1 was higher than that in the group without TGF-beta1 (P < 0.05).
  • CONCLUSIONS: TGF-beta1 could influence EDA region splicings and upregulate the expression of EDA region in Tca83, SACC-83 and SACC-LM cells, and might play an important role in accelerating oral carcinoma cells adhesion and tumor invasion and metastasis.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Carcinoma, Squamous Cell / pathology. Fibronectins / metabolism. Mouth Neoplasms / pathology. Transforming Growth Factor beta1 / pharmacology
  • [MeSH-minor] Cell Line, Tumor. Humans. RNA, Messenger / metabolism






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