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1. Murray BW, Lyons LC, Mancino AT, Huerta S: A report of laryngeal adenocystic carcinoma metastatic to the spleen and the role of splenectomy in the management of metastatic disease: a case report. J Med Case Rep; 2010;4:207

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A report of laryngeal adenocystic carcinoma metastatic to the spleen and the role of splenectomy in the management of metastatic disease: a case report.
  • INTRODUCTION: Adenoid cystic carcinoma (ACC) of the larynx is a rare malignancy characterized by an indolent course and late pulmonary metastases.
  • Metastases from the larynx to the spleen are an unusual event.
  • In the present report, we discuss a patient with adenoid cystic carcinoma of the larynx metastatic to the spleen.
  • We review the clinical presentation and course of adenoid cystic carcinoma, as well as the role of splenectomy for metastases.
  • CASE PRESENTATION: We present a case of laryngeal adenoid cystic carcinoma in a 26-year-old Caucasian man treated with total laryngectomy and ionizing radiation.

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  • (PMID = 20604942.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2908633
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2. Zvrko E, Golubović M: Laryngeal adenoid cystic carcinoma. Acta Otorhinolaryngol Ital; 2009 Oct;29(5):279-82
Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laryngeal adenoid cystic carcinoma.
  • Adenoid cystic carcinomas are malignant tumours and occur in the major and the minor salivary glands.
  • Laryngeal adenoid cystic carcinomas are rare and account for less than 1% of all malignant tumours in the larynx.
  • Adenoid cystic carcinoma is characterised by slow progression, multiple recurrences and late distant metastasis.
  • The aetiology of adenoid cystic carcinoma remains unknown.
  • In this article, the case of laryngeal adenoid cystic carcinoma is described in a 55-year-old male patient who presented with a 3-month history of prelaryngeal pain.
  • For patients with laryngeal adenoid cystic carcinomas, regular and long-term follow-up is mandatory, in order to detect relapses and metastases.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Carcinoma, Adenoid Cystic / surgery. Laryngeal Neoplasms / pathology. Laryngeal Neoplasms / surgery

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  • (PMID = 20162031.001).
  • [ISSN] 1827-675X
  • [Journal-full-title] Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale
  • [ISO-abbreviation] Acta Otorhinolaryngol Ital
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2821129
  • [Keywords] NOTNLM ; Adenoid cystic carcinoma / Laryngectomy / Larynx / Malignant tumours
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3. Del Negro A, Ichihara E, Tincani AJ, Altemani A, Martins AS: Laryngeal adenoid cystic carcinoma: case report. Sao Paulo Med J; 2007 Sep 6;125(5):295-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laryngeal adenoid cystic carcinoma: case report.
  • CONTEXT: Adenoid cystic carcinomas are malignant tumors that occur in both the major and the minor salivary glands.
  • A laryngeal location is rare because of the paucity of accessory salivary glands in this area.
  • Adenoid cystic carcinomas account for less than 1% of all malignant tumors in the larynx, and only about 120 cases have been reported in the literature.
  • In this article, we describe a case of laryngeal adenoid cystic carcinoma and discuss its clinical characteristics and treatment.
  • CASE REPORT: We report on a case of laryngeal adenoid cystic carcinoma in a 55 year-old female patient who presented with dyspnea and hoarseness.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Laryngeal Neoplasms / pathology

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  • (PMID = 18094899.001).
  • [ISSN] 1516-3180
  • [Journal-full-title] São Paulo medical journal = Revista paulista de medicina
  • [ISO-abbreviation] Sao Paulo Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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4. Pino Rivero V, Pantoja Hernández CG, González Palomino A, Trinidad Ramos G, Pardo Romero G, Marcos García M, Pereda Tamayo JM, Blasco Huelva A: [Adenoid cystic carcinoma of the larynx-hypopharynx. A case report and review of the literature]. An Otorrinolaringol Ibero Am; 2006;33(4):339-45
Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Adenoid cystic carcinoma of the larynx-hypopharynx. A case report and review of the literature].
  • [Transliterated title] Carcinoma adenoide quístico de laringe-hipofaringe. A propósito de un caso y revisión de la literatura.
  • Laryngeal or hypopharyngeal localization of adenoid cystic carcinoma is rare due to the poor distribution of the accesory salivary glands in this area.
  • We report one case of such neoplasm on that area, with its diagnosis confirmed histologically.
  • We review the literature of this tumor whose prognosis is much worse than epidermoid or scamous carcinoma.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Carcinoma, Adenoid Cystic / surgery. Hypopharyngeal Neoplasms / pathology. Hypopharyngeal Neoplasms / surgery. Laryngeal Neoplasms / pathology. Laryngeal Neoplasms / surgery

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  • (PMID = 16910388.001).
  • [ISSN] 0303-8874
  • [Journal-full-title] Anales otorrinolaringológicos ibero-americanos
  • [ISO-abbreviation] An Otorrinolaringol Ibero Am
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 18
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5. Messaoudi C, Larouk R, Baili S, Noui B, Benchaoui M, Benkadri H, Belbekri F: [Adenoid cystic carcinoma of the larynx. A case report and review of the literature]. Rev Laryngol Otol Rhinol (Bord); 2007;128(1-2):97-100
Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Adenoid cystic carcinoma of the larynx. A case report and review of the literature].
  • [Transliterated title] Carcinome adénoïde kystique du larynx. Revue de la littérature, à propos d'un cas.
  • Cylindroma of the head and neck, known as "cystic adenoid carcinoma", begins more often at the expense of the all glandular structures of ectodermic origin, in particularly at the minor and principal salivary glands.
  • However the laryngeal localization is rare, by way of the low distribution of the accessory glands at this level.
  • A biopsy is realized under general anesthesia, and the histopathologic results has been a laryngeal CAK, a radio therapy was also under taken, because the patient refused the surgery.
  • CONCLUSION: The laryngeal cylindroma is rare.
  • The symptomatology does not show a proper characteristic, the diagnosis is a histological finding, and the natural evolution is marked by the very show development of this tumour the onset of cervical lymphatic adenopathy.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Laryngeal Neoplasms / pathology

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  • (PMID = 17633677.001).
  • [ISSN] 0035-1334
  • [Journal-full-title] Revue de laryngologie - otologie - rhinologie
  • [ISO-abbreviation] Rev Laryngol Otol Rhinol (Bord)
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 33
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6. Moukarbel RV, Goldstein DP, O'Sullivan B, Gullane PJ, Brown DH, Wang L, Irish JC: Adenoid cystic carcinoma of the larynx: a 40-year experience. Head Neck; 2008 Jul;30(7):919-24
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenoid cystic carcinoma of the larynx: a 40-year experience.
  • BACKGROUND: Laryngeal adenoid cystic carcinoma (ACC) is a rare disease.
  • CONCLUSION: Laryngeal ACC is a rare disease with a high rate of distant recurrence.
  • [MeSH-major] Carcinoma, Adenoid Cystic / mortality. Carcinoma, Adenoid Cystic / surgery. Laryngeal Neoplasms / mortality. Laryngeal Neoplasms / surgery. Laryngectomy / methods. Neoplasm Recurrence, Local / mortality

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  • (PMID = 18302260.001).
  • [ISSN] 1097-0347
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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7. Wang HL, Xu L, Li FJ: Subglottic adenoid cystic carcinoma mistaken for asthma. J Zhejiang Univ Sci B; 2009 Sep;10(9):707-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Subglottic adenoid cystic carcinoma mistaken for asthma.
  • Adenoid cystic carcinoma rarely occurs within the subglottic larynx.
  • In this study, a case of subglottic adenoid cystic carcinoma was reported.
  • Until a sudden dyspnea, a cervicothoracic computerized tomography (CT) revealed that her upper airway was obstructed by a laryngeal tumor.
  • The patient was diagnosed with a subglottic adenoid cystic carcinoma and treated with complete surgical excision and adjuvant radiation therapy.
  • Follow-up endoscopy and laryngeal magnetic resonance imaging (MRI) at six months showed no recurrence of the tumor.
  • The diagnosis of subglottic adenoid cystic carcinoma should be considered in patients who are characterized by dyspnea, cough, and stridor, but do not respond to regular anti-asthmatic therapy.
  • [MeSH-major] Asthma / diagnosis. Carcinoma, Adenoid Cystic / diagnosis. Glottis / radiography. Laryngeal Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged

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  • (PMID = 19735105.001).
  • [ISSN] 1862-1783
  • [Journal-full-title] Journal of Zhejiang University. Science. B
  • [ISO-abbreviation] J Zhejiang Univ Sci B
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2738842
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8. Luna Ortiz K, Carmona Luna T, Herrera Gómez A, Cano Valdez AM: Macroglossia caused by adenoid cystic carcinoma. Case report. Med Oral Patol Oral Cir Bucal; 2008 Jun;13(6):E395-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Macroglossia caused by adenoid cystic carcinoma. Case report.
  • She had been treated before with tracheostomy and gastrostomy due to an adenoid cystic carcinoma (ACC) of the mobile tongue, in clinical stage IVC.
  • She was subjected to total glossectomy with larynx preservation, modified radical dissection of the right neck and of the left supraomohyoid muscle, as well as reconstruction using a free flap from the rectus abdominus.
  • [MeSH-major] Carcinoma, Adenoid Cystic / complications. Macroglossia / etiology. Tongue Neoplasms / complications

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  • (PMID = 18521061.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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9. Aydin O, Ustündağ E, Işeri M, Erçin C: Laryngeal adenoid cystic carcinoma in an adolescent. Kulak Burun Bogaz Ihtis Derg; 2008 Sep-Oct;18(5):319-22
Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laryngeal adenoid cystic carcinoma in an adolescent.
  • Malignant tumors of the larynx are extremely rare in children and adolescents.
  • Adenoid cystic carcinoma accounts for less than 1% of all malignant tumors in the larynx.
  • We presented a 16-year-old girl with subglottic adenoid cystic carcinoma, whose symptoms of prolonged and exacerbating dyspnea had been attributed to asthma at another medical center.
  • [MeSH-major] Carcinoma, Adenoid Cystic / diagnosis. Laryngeal Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Dyspnea / etiology. Female. Humans. Laryngectomy. Laryngoscopy. Larynx, Artificial. Magnetic Resonance Imaging. Radiotherapy, Adjuvant. Thyroid Neoplasms / radiotherapy. Thyroid Neoplasms / secondary. Thyroid Neoplasms / surgery. Thyroidectomy. Tomography, X-Ray Computed

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  • (PMID = 19155680.001).
  • [ISSN] 1300-7475
  • [Journal-full-title] Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
  • [ISO-abbreviation] Kulak Burun Bogaz Ihtis Derg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Turkey
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10. Khan AR, Jan A, Nawaz G, Zaman N: Adenoid cystic carcinoma of larynx. J Coll Physicians Surg Pak; 2006 Oct;16(10):669-70
Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenoid cystic carcinoma of larynx.
  • Direct laryngoscopy showed mass in right side of subglottic region, and biopsy-proven adenoid cystic carcinoma.
  • [MeSH-major] Carcinoma, Adenoid Cystic / diagnosis. Laryngeal Neoplasms / diagnosis

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  • (PMID = 17007759.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
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11. Zald PB, Weber SM, Schindler J: Adenoid cystic carcinoma of the subglottic larynx: a case report and review of the literature. Ear Nose Throat J; 2010 Apr;89(4):E27-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenoid cystic carcinoma of the subglottic larynx: a case report and review of the literature.
  • Laryngeal adenoid cystic carcinoma (ACC) is a rare clinical entity that poses a number of diagnostic and therapeutic challenges.
  • We present a case of ACC of the subglottic larynx, and we review its diagnosis and management.
  • We also discuss the workup of submucosal masses of the subglottic larynx, with an emphasis on clinical and radiologic diagnosis, surgical treatment, radiotherapy, and emerging therapies.
  • The presence of a submucosal mass in the subglottic larynx should raise suspicion for the presence of ACC.
  • [MeSH-major] Carcinoma, Adenoid Cystic / diagnosis. Laryngeal Neoplasms / diagnosis. Laryngoscopy. Tomography, X-Ray Computed

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  • (PMID = 20397134.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 20
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12. González-Vela MC, Val-Bernal JF, Mayorga M, Zaldumbide L, Báscones M: Adenoid squamous cell carcinoma of the larynx: an uncommon histological variant of squamous cell carcinoma. APMIS; 2006 Jun;114(6):470-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenoid squamous cell carcinoma of the larynx: an uncommon histological variant of squamous cell carcinoma.
  • Adenoid squamous cell carcinoma (ASCC) or acantholytic squamous cell carcinoma is a well-recognized variant of squamous cell carcinoma.
  • We report a case of ASCC in the larynx of a 75-year-old man with a history of odynophagia and dysphonia of 3 months' duration that presented as an exophytic lesion on the right vocal cord.
  • Biopsy was performed and the histological diagnosis was squamous cell carcinoma.
  • Microscopically, the tumor showed a prominent alveolar pattern with cystic degeneration of the neoplastic epithelium and formation of pseudoglandular structures.
  • Transition areas from conventional squamous cell carcinoma to adenoid pattern were found.
  • To the best of our knowledge this is only the third case of ASCC reported in the larynx.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Laryngeal Neoplasms / pathology

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  • (PMID = 16856971.001).
  • [ISSN] 0903-4641
  • [Journal-full-title] APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
  • [ISO-abbreviation] APMIS
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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13. Mücke T, Tannapfel A, Kesting MR, Wagenpfeil S, Robitzky LK, Wolff KD, Hölzle F: Adenoid cystic carcinomas of minor salivary glands. Auris Nasus Larynx; 2010 Oct;37(5):615-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenoid cystic carcinomas of minor salivary glands.
  • OBJECTIVES: Adenoid cystic carcinoma (ACC) is a very rare epithelioid tumor with different prognostic factors relating to overall survival.
  • [MeSH-major] Carcinoma, Adenoid Cystic / diagnosis. Neoplasm Recurrence, Local / diagnosis. Salivary Gland Neoplasms / diagnosis. Salivary Glands, Minor

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  • [Copyright] Copyright 2010 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 20181451.001).
  • [ISSN] 1879-1476
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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14. Ide F, Mishima K, Yamada H, Saito I: Adenoid cystic carcinoma ex pleomorphic adenoma of the parotid gland. Head Neck Pathol; 2009 Jun;3(2):159-62
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenoid cystic carcinoma ex pleomorphic adenoma of the parotid gland.
  • There is a considerable variation in the histologic subtype of epithelial malignancies among carcinoma ex pleomorphic adenomas (CXPA) and virtually any known carcinoma entity can develop.
  • To our knowledge, adenoid cystic carcinoma (AdCC) ex PA is quite rare despite the fact that de novo AdCC is the fourth most common salivary gland malignancy.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Carcinoma, Adenoid Cystic / pathology. Parotid Neoplasms / pathology

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  • (PMID = 19644550.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Adenoid cystic carcinoma / Carcinoma ex pleomorphic adenoma / High-grade malignancy / Parotid gland
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15. Ciccolallo L, Licitra L, Cantú G, Gatta G, EUROCARE Working Group: Survival from salivary glands adenoid cystic carcinoma in European populations. Oral Oncol; 2009 Aug;45(8):669-74
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Survival from salivary glands adenoid cystic carcinoma in European populations.
  • Adenoid cystic carcinoma (ACC) of salivary gland origin is rare.
  • Relative survival by sex, age, period of diagnosis, region, site and stage, and the adjusted relative excess risk (RER) of death were estimated.
  • Survival since diagnosis was 94%, 78% and 65% at 1, 5 and ten years, respectively.
  • ACCs in nasal cavity (RER 2.6), pharynx (RER 3.5) and larynx and bronchus (RER 3.9) had a worse prognosis compared to those of oral cavity.
  • A strong effect of stage at diagnosis on RERs and some worsening of survival at five years over time (80% in 1983-1985, 76% in 1992-1994) were also evident.
  • The findings of the present study, as those from clinical studies, confirm the important impact of primary site and stage at diagnosis on survival.
  • [MeSH-major] Carcinoma, Adenoid Cystic / mortality. Rare Diseases / mortality. Salivary Gland Neoplasms / mortality

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  • (PMID = 19095489.001).
  • [ISSN] 1879-0593
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Investigator] Oberaigner W; Storm HH; Aareleid T; Jechova M; Rousarova M; Hakulinen T; Hédelin G; Tron I; Le Gall E; Launoy G; Macé-Lesec'h J; Faivre J; Chaplain G; Carli PM; Danzon A; Tretarre B; Colonna M; Lacour B; Raverdy N; Berger C; Freycon B; Grosclaude P; Estève J; Kaatsch P; Ziegler H; Hölzel D; Schubert Fritschle G; Tryggvadottir L; Berrino F; Allemani C; Baili P; Ciccolallo L; Crosignani P; Gatta G; Micheli A; Sant M; Taussig E; Sowe S; Ferretti S; Conti E; Vercelli M; Quaglia A; Pannelli F; Federico M; Artioli ME; Ponz De Leon M; Benatti P; De Lisi V; Servente L; Zanetti R; Patriarca S; Magnani C; Pastore G; Gafa L; Tumino R; Falcini F; Budroni M; Paci E; Crocetti E; Zambon P; Guzzinati S; Capocaccia R; Carrani E; De Angelis R; Roazzi P; Santaquilani M; Tavilla A; Valente F; Verdecchia A; Dalmas M; Langmark F; Andersen A; Rachtan J; Bielska-Lasota M; Wronkowski Z; Plesko I; Obsitníková A; Pompe-Kirn V; Primic Zakelj M; Izarzugaza I; Martinez-Garcia C; Garau I; Navarro C; Chirlaque MD; Ardanaz E; Moreno C; Galceran J; Torrella A; Peris-Bonet R; Barlow L; Möller L; Jundt G; Lutz JM; Bouchardy C; Coebergh JW; Visser O; Godward S; Coleman MP; Williams EM; Forman D; Quinn MJ; Roche M; Edwards S; Stiller C; Verne J; Møller H; Bell J; Botha JL; Lawrence G; Black R; Steward JA
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16. Kumamoto M, Kuratomi Y, Yasumatsu R, Nakashima T, Masuda M, Inokuchi A: Expression of laminin 5 basement membrane components in invading and recurring adenoid cystic carcinoma of the head and neck. Auris Nasus Larynx; 2006 Jun;33(2):167-72
MedlinePlus Health Information. consumer health - Head and Neck Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of laminin 5 basement membrane components in invading and recurring adenoid cystic carcinoma of the head and neck.
  • OBJECTIVE: Adenoid cystic carcinoma (ACC) of the head and neck grows slowly with structural differentiation, however, this tumor nevertheless also shows a highly invasive potential and a high recurrence rate.
  • [MeSH-major] Carcinoma, Adenoid Cystic / genetics. Carcinoma, Adenoid Cystic / metabolism. Head and Neck Neoplasms / genetics. Head and Neck Neoplasms / metabolism. Laminin / genetics. Laminin / metabolism

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  • (PMID = 16332421.001).
  • [ISSN] 0385-8146
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Collagen Type IV; 0 / LAMC2 protein, human; 0 / Laminin
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17. Yang PY, Liu MS, Chen CH, Lin CM, Tsao TC: Adenoid cystic carcinoma of the trachea: a report of seven cases and literature review. Chang Gung Med J; 2005 May;28(5):357-63
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  • [Title] Adenoid cystic carcinoma of the trachea: a report of seven cases and literature review.
  • BACKGROUND: Adenoid cystic carcinoma (ACC) of the trachea is rare.
  • For these seven patients the clinical manifestations and period from initial symptoms to diagnosis, treatment and outcome are presented.
  • In a patient with the tumor in the upper area of the trachea, the tumor involved the cricoid ring, larynx, and subglottic area.
  • The time from first symptoms to diagnosis varied, ranging from weeks to more than 1 year.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Tracheal Neoplasms / pathology

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  • (PMID = 16086551.001).
  • [ISSN] 2072-0939
  • [Journal-full-title] Chang Gung medical journal
  • [ISO-abbreviation] Chang Gung Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China (Republic : 1949- )
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18. Bilić M, Prgomet D, Kovac L, Topić I, Katić V: [Nonepidermoid carcinomas of the larynx--15 years experience in the single institution]. Lijec Vjesn; 2009 Jul-Aug;131(7-8):196-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Nonepidermoid carcinomas of the larynx--15 years experience in the single institution].
  • Nonsquamous carcinomas of the larynx are very rare and present a diverse group of diseases.
  • Polypoid and submucosal lesions of the larynx are characteristic findings in these tumors, and probably the reason for late diagnosis even in the presence of symptoms.
  • According to cell origin, nonsquamous carcinomas are classified into secretory, connective tissue, lymphoreticular, melanoma, or metastatic carcinoma.
  • In this study, 771 laryngeal carcinomas treated during a 15-year (1990-2005) period at the Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Center Zagreb, were reviewed to yield 11 cases of nonsquamous carcinoma, including one case of neuroendocrine carcinoma, leiomyosarcoma, fibrosarcoma, rhabdomyosarcoma, adenoid cystic carcinoma, and plasmacytoma, 2 cases of chondrosarcoma, and 3 cases of high-grade mucoepidermoid carcinoma.
  • [MeSH-major] Carcinoma. Laryngeal Neoplasms

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  • (PMID = 19769280.001).
  • [ISSN] 0024-3477
  • [Journal-full-title] Lijec̆nic̆ki vjesnik
  • [ISO-abbreviation] Lijec Vjesn
  • [Language] hrv
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Croatia
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19. Ganly I, Patel SG, Coleman M, Ghossein R, Carlson D, Shah JP: Malignant minor salivary gland tumors of the larynx. Arch Otolaryngol Head Neck Surg; 2006 Jul;132(7):767-70
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  • [Title] Malignant minor salivary gland tumors of the larynx.
  • OBJECTIVE: To report our experience in treating patients with malignant minor salivary gland tumors of the larynx.
  • PATIENTS: Twelve patients with malignant minor salivary gland tumors of the larynx were identified from a search of the institutional databases and pathology records at Memorial Sloan-Kettering Cancer Center, New York, NY, between the years 1970 and 2003.
  • RESULTS: Ten patients (83%) had adenoid cystic carcinoma and 2 (17%) had myoepithelial carcinoma.
  • CONCLUSIONS: Up to 60% of patients with malignant minor salivary gland tumors of the larynx will develop recurrent disease locally, regionally, or at distant sites.
  • In adenoid cystic carcinoma, regional recurrence is rare, but distant recurrence is common and may occur up to 10 years after the index therapy.
  • For both adenoid cystic and myoepithelial carcinoma, partial surgery is possible in selected cases, but because of the high propensity for submucosal spread and perineural and lymphovascular invasion, total laryngectomy is usually recommended.
  • [MeSH-major] Laryngeal Neoplasms / therapy. Salivary Gland Neoplasms / therapy

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  • (PMID = 16847187.001).
  • [ISSN] 0886-4470
  • [Journal-full-title] Archives of otolaryngology--head & neck surgery
  • [ISO-abbreviation] Arch. Otolaryngol. Head Neck Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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20. Zeng Q, Tang PZ, Xu ZG, Qi YF, Wu XX, Liu WS: [Malignant minor salivary gland tumors of the larynx]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2009 Jan;44(1):40-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Malignant minor salivary gland tumors of the larynx].
  • OBJECTIVE: To study the clinical features, treatment and prognosis of malignant minor salivary gland tumors of the larynx.
  • METHODS: Treatment and outcome were retrospectively analyzed in a consecutive series of 15 patients with malignant minor salivary gland tumors of the larynx treated in this hospital from 1959 to 2005.
  • Ten patients (66.7%) had adenoid cystic carcinoma and 2 (13.3%) had adenocarcinoma.
  • The other three patients had mucoepidermoid carcinomas, polymorphic adenocarcinoma and base cell carcinoma respectively.
  • CONCLUSIONS: Minor salivary gland carcinomas of the larynx are rare and they are prone to the local recurrence and the distant metastasis in advanced stage.
  • [MeSH-major] Laryngeal Neoplasms / therapy. Salivary Gland Neoplasms / therapy. Salivary Glands, Minor / pathology

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  • (PMID = 19484987.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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21. Vasudev P, Boutross-Tadross O, Radhi J: Basaloid squamous cell carcinoma: two case reports. Cases J; 2009;2:9351
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  • [Title] Basaloid squamous cell carcinoma: two case reports.
  • Basaloid squamous cell carcinoma (BSCC) is a rare and aggressive variant of squamous cell carcinoma (SCC) that occurs preferentially in the upper aerodigestive tract.
  • BSCC of the head and neck should be distinguished from adenoid cystic carcinoma, small cell neuroendocrine carcinoma, basal cell adenocarcinoma, adenosquamous carcinoma, squamous cell carcinoma, spindle cell squamous carcinoma, mucoepidermoid carcinoma, and adenoid cystic carcinoma.

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  • [Cites] Eur J Cancer. 2008 Jan;44(2):244-50 [18096379.001]
  • [Cites] Auris Nasus Larynx. 2007 Mar;34(1):119-23 [17141998.001]
  • [Cites] Histopathology. 2000 Sep;37(3):218-23 [10971697.001]
  • [Cites] Hum Pathol. 1986 Nov;17(11):1158-66 [3770734.001]
  • [Cites] Ophthalmology. 1993 Nov;100(11):1720-2 [8233401.001]
  • (PMID = 20062602.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2804002
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22. Aksu K, Aktaş Z, Aksu F, Orsel O, Demirağ F, Sipit T, Firat Güven S: Spindle cell sarcomatoid carcinoma: first case reported in the trachea. Tuberk Toraks; 2009;57(3):337-41

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spindle cell sarcomatoid carcinoma: first case reported in the trachea.
  • Microscopically, the tumor was composed of fascicular pattern of spindle cells with atypical mitotic figures and nuclear pleomorphism, positively reactive to epithelial membrane antigen supporting a diagnosis of tumour with epithelial differentiation.
  • These findings supported the diagnosis of a spindle cell sarcomatoid carcinoma of trachea.
  • Spindle cell carcinoma cases are reported in many sites, such as head and neck region, larynx, digestive tract, breast, kidney, genital tract, skin and lung, but to our knowledge, not in trachea.
  • Primary malignant tracheal tumours consist mainly of squamous cell carcinoma and adenoid cystic carcinoma and generally have an aggressive course with poor prognosis.
  • We report the first presentation of a spindle cell sarcomatoid carcinoma of trachea together with the clinical course of the patient.
  • [MeSH-major] Carcinoma / pathology. Tracheal Neoplasms / pathology

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  • (PMID = 19787474.001).
  • [ISSN] 0494-1373
  • [Journal-full-title] Tüberküloz ve toraks
  • [ISO-abbreviation] Tuberk Toraks
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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23. Eslami B, Rahimi H, Rahimi F, Khiavi MM, Ebadifar A: Diagnostic value of silver nitrate staining for nucleolar organizer regions in selected head and neck tumors. J Cancer Res Ther; 2006 Jul-Sep;2(3):129-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: The present study is aimed to assess the usefulness of silver nitrate staining of nucleolar organizer regions (NORs) as a quantitative criterion for the diagnosis of selected head and neck tumors.
  • The samples consisted of 21 squamous cell carcinoma (SCC) of larynx, 28 SCC of oral mucosa and 36 samples of most common salivary gland tumors.
  • RESULTS: A significant difference was seen in the number of AgNOR dots between oral and laryngeal SCC with surrounding dysplastic and normal tissues (P < 0.001) and also between mucoepidermoid carcinoma and adenoid cystic carcinoma with pleomorphic adenoma and normal salivary gland tissue (P < 0.001).
  • CONCLUSION: The silver nitrate staining for NORs is a useful method for aiding the diagnosis of malignant and dysplastic mucosal lesions and also malignant and benign salivary gland tumors.
  • [MeSH-major] Carcinoma, Squamous Cell / diagnosis. Head and Neck Neoplasms / diagnosis. Nucleolus Organizer Region / metabolism. Silver Staining
  • [MeSH-minor] Adenoma, Pleomorphic / diagnosis. Adenoma, Pleomorphic / metabolism. Carcinoma, Adenoid Cystic / diagnosis. Carcinoma, Adenoid Cystic / metabolism. Carcinoma, Mucoepidermoid / diagnosis. Carcinoma, Mucoepidermoid / metabolism. Humans. Salivary Gland Neoplasms / diagnosis. Salivary Gland Neoplasms / metabolism

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  • (PMID = 17998691.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
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24. Desai SC, Sung CK, Jang DW, Genden EM: Transoral robotic surgery using a carbon dioxide flexible laser for tumors of the upper aerodigestive tract. Laryngoscope; 2008 Dec;118(12):2187-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To determine the safety, feasibility, and efficacy of coupling transoral robotic technology with the flexible carbon dioxide (CO2) laser for various tumors of the oropharynx and supraglottic larynx.
  • RESULTS: Seven male patients with early carcinoma of the oropharynx or larynx successfully underwent tumor extirpation with the transoral robot and the flexible CO2 laser.
  • We were unable to gain access to the supraglottic larynx in one female patient.
  • The final pathology revealed seven patients with squamous cell carcinoma and one patient with adenoid cystic carcinoma.
  • [MeSH-major] Carcinoma, Adenoid Cystic / surgery. Carcinoma, Squamous Cell / surgery. Laryngeal Neoplasms / surgery. Laryngoscopes. Laser Therapy / instrumentation. Lasers, Gas / therapeutic use. Oropharyngeal Neoplasms / surgery. Robotics / instrumentation. Surgery, Computer-Assisted / instrumentation

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  • (PMID = 19029867.001).
  • [ISSN] 1531-4995
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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25. Reiter ER, Idowu MO, Powers CN: Unusual paratracheal masses presenting with vocal fold paralysis. Ear Nose Throat J; 2006 Feb;85(2):112-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The other patient was a 53-year-old man with an enlarged left thyroid lobe, tumor invasion of the adjacent larynx and trachea, and multiple pulmonary nodules all due to adenoid cystic carcinoma.
  • Fine-needle aspiration cytology is often helpful in making a definitive diagnosis, but incisional biopsy is necessary in some cases.
  • [MeSH-major] Carcinoma, Adenoid Cystic / diagnosis. Lymphoma, B-Cell / diagnosis. Mediastinal Neoplasms / diagnosis. Tracheal Neoplasms / diagnosis. Vocal Cord Paralysis / etiology
  • [MeSH-minor] Adult. Algorithms. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Cyclophosphamide / therapeutic use. Diagnosis, Differential. Doxorubicin / therapeutic use. Humans. Male. Middle Aged. Prednisone / therapeutic use. Retrospective Studies. Thyroid Neoplasms / diagnosis. Tomography, X-Ray Computed. Treatment Outcome. Vincristine / therapeutic use

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  • (PMID = 16579201.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone; CHOP protocol
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26. Gaissert HA, Grillo HC, Shadmehr BM, Wright CD, Gokhale M, Wain JC, Mathisen DJ: Laryngotracheoplastic resection for primary tumors of the proximal airway. J Thorac Cardiovasc Surg; 2005 May;129(5):1006-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Primary tumors of the airway with proximity to vocal cords and recurrent laryngeal nerves can be resected with sparing of the larynx.
  • RESULTS: Twenty-five patients aged 15 to 77 years presented with adenoid cystic carcinomas (n = 9), squamous cell carcinomas (n = 6), and other airway tumors (n = 10).
  • Seven patients without hoarseness required resection of the recurrent laryngeal nerve, and 4 other patients with hoarseness did not.
  • [MeSH-major] Laryngeal Neoplasms / surgery. Laryngectomy / methods. Tracheal Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Carcinoma, Adenoid Cystic / surgery. Carcinoma, Mucoepidermoid / surgery. Carcinoma, Squamous Cell / surgery. Chondrosarcoma / surgery. Cough / etiology. Deglutition Disorders / etiology. Dyspnea / etiology. Hemoptysis / etiology. Hoarseness / etiology. Humans. Massachusetts / epidemiology. Middle Aged. Neoplasm Recurrence, Local / epidemiology. Neoplasm Recurrence, Local / etiology. Pain / etiology. Respiratory Sounds / etiology. Retrospective Studies. Sarcoma / surgery. Survival Analysis. Treatment Outcome

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  • (PMID = 15867773.001).
  • [ISSN] 0022-5223
  • [Journal-full-title] The Journal of thoracic and cardiovascular surgery
  • [ISO-abbreviation] J. Thorac. Cardiovasc. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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27. Jung WS, Ahn KJ, Park MR, Kim JY, Choi JJ, Kim BS, Hahn ST: The radiological spectrum of orbital pathologies that involve the lacrimal gland and the lacrimal fossa. Korean J Radiol; 2007 Jul-Aug;8(4):336-42
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  • In lacrimal gland epithelial tumors, benign pleomorphic adenomas are seen most commonly with a well defined benign appearance, and a malignant adenoid cystic carcinoma is seen with a typical invasive malignant appearance.
  • However, a malignant myoepithelial carcinoma is seen with a benign looking appearance.
  • The developmental cystic lesions found in the lacrimal fossa such as dermoid and epidermoid cysts can be diagnosed when the cyst involves the superior temporal quadrant of the orbit and manifests as a non-enhancing cystic mass and, in case of a lipoma, it is diagnosed as a total fatty mass.
  • [MeSH-minor] Carcinoma, Squamous Cell / radiography. Conjunctival Neoplasms / radiography. Cysts / radiography. Hemangiopericytoma / radiography. Humans. Lacrimal Apparatus Diseases / radiography. Lipoma / radiography. Lymphoma / radiography. Neoplasms, Glandular and Epithelial / radiography. Neurofibroma / radiography. Sarcoma, Myeloid / radiography

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  • [Cites] Br J Ophthalmol. 2000 Mar;84(3):251-8 [10684833.001]
  • [Cites] Auris Nasus Larynx. 2002 Jan;29(1):77-82 [11772496.001]
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  • (PMID = 17673845.001).
  • [ISSN] 1229-6929
  • [Journal-full-title] Korean journal of radiology
  • [ISO-abbreviation] Korean J Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Korea (South)
  • [Number-of-references] 9
  • [Other-IDs] NLM/ PMC2627159
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28. Cansiz H, Yener M, Bozkurt AK, Demir A, Demirkaya A, Sekercioglu N: Surgical treatment of laryngeal tumors with subglottic extension and tracheal tumors with composite nasal septal cartilage graft: technique and outcome. Auris Nasus Larynx; 2008 Sep;35(3):363-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical treatment of laryngeal tumors with subglottic extension and tracheal tumors with composite nasal septal cartilage graft: technique and outcome.
  • OBJECTIVE: Composite nasal septal cartilage grafts (CNSCG) are effective grafting materials in laryngeal and tracheal reconstruction following tumor resection.
  • METHODS: Between 1985 and 2005, we used CNSCG for the reconstruction of defects following resection of laryngeal tumors with subglottic extension (20 cases), subglottic mesenchymal tumors (2 cases), invasive thyroid carcinoma (4 cases), tracheal tumors (3 cases) and esophagus carcinoma with tracheal invasion (1 case) in total of 30 patients.
  • Overall complications consisted of subglottic stenosis in one case, and unilateral paralysis of recurrent laryngeal nerve in two cases.
  • One patient with subglottic laryngeal carcinoma died due to neck and distant metastases 4 years after the operation.
  • The patient with esophagus carcinoma and tracheal invasion was treated by total esophagectomy, gastric pull-up, tracheal resection and CNSCG reconstruction.
  • CONCLUSION: Free composite cartilage graft is a reliable material in the reconstruction of defects after surgery of laryngeal tumors with subglottic extension, invasive thyroid and esophagus tumors and well-selected tracheal tumors.
  • [MeSH-major] Cartilage / transplantation. Laryngeal Neoplasms / surgery. Tracheal Neoplasms / surgery
  • [MeSH-minor] Adenocarcinoma / pathology. Adenocarcinoma / surgery. Adenocarcinoma, Papillary / pathology. Adenocarcinoma, Papillary / surgery. Adult. Aged. Carcinoma, Adenoid Cystic / pathology. Carcinoma, Adenoid Cystic / surgery. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Esophageal Neoplasms / pathology. Esophageal Neoplasms / surgery. Female. Follow-Up Studies. Humans. Laryngectomy / methods. Magnetic Resonance Imaging. Male. Mesenchymoma / pathology. Mesenchymoma / surgery. Middle Aged. Neoplasm Invasiveness. Papilloma / pathology. Papilloma / surgery. Reconstructive Surgical Procedures / methods. Thyroid Neoplasms / pathology. Thyroid Neoplasms / surgery

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  • (PMID = 17997246.001).
  • [ISSN] 0385-8146
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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29. Crain N, Nelson BL, Barnes EL, Thompson LD: Ceruminous gland carcinomas: a clinicopathologic and immunophenotypic study of 17 cases. Head Neck Pathol; 2009 Mar;3(1):1-17

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Histologically, the tumors demonstrated a solid to cystic pattern, composed of an infiltrating glandular to cribriform arrangement of epithelial cells.
  • Tumors were divided into three types of adenocarcinoma based on pattern of growth and cell type (ceruminous, NOS [n = 12], adenoid cystic [n = 4], mucoepidermoid [n = 1]).
  • CK7 and CD117 highlighted the luminal cells, while S1-00 protein showed a predilection for the basal cells of ceruminous and adenoid cystic carcinomas.
  • CONCLUSION: Ceruminous-type carcinomas, with the exception of ceruminous mucoepidermoid carcinoma, all demonstrated a dual cell population of basal myoepithelial-type cells and luminal apocrine cells.
  • [MeSH-major] Carcinoma / pathology. Ear Neoplasms / pathology. Ear, External / pathology

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  • (PMID = 20596983.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ PMC2807538
  • [Keywords] NOTNLM ; Adenoid cystic / Carcinoma / Ceruminal / Ceruminous / Ear / Gland / Immunohistochemistry / Mucoepidermoid / Prognosis
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30. Katori H, Nozawa A, Tsukuda M: Increased expression of cyclooxygenase-2 and Ki-67 are associated with malignant transformation of pleomorphic adenoma. Auris Nasus Larynx; 2007 Mar;34(1):79-84
MedlinePlus Health Information. consumer health - Salivary Gland Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVES: In the present study, we attempted to identify cyclooxygenase-2 (COX-2) expression and Ki-67 index in carcinoma ex-pleomorphic adenoma (Ca ex-PA) using quantitative immunohistochemical analysis and to compare the benign component of the neoplasia.
  • All Ca ex-PA showed only one malignant histological component: adenocarcinoma (23 cases), adenoid-cystic carcinoma (10), epithelial-myoepithelial carcinoma (7).

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  • (PMID = 17049779.001).
  • [ISSN] 0385-8146
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antibodies; 0 / Ki-67 Antigen; EC 1.14.99.1 / Cyclooxygenase 2
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31. Biel MA: Photodynamic therapy of head and neck cancers. Methods Mol Biol; 2010;635:281-93
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The predominant histology is squamous cell carcinoma, but other histologies treated include mucosal melanoma, Kaposi's sarcoma, adenocarcinoma, metastatic breast carcinoma, and adenoid cystic carcinoma.
  • Patients with early stage cancers or early recurrences in the oral cavity and larynx (Cis, T1, T2) tend to have an excellent response to PDT.
  • Of 518 patients treated with Cis, T1, or T2 cancers of the oral cavity, larynx, pharynx, and nasopharynx, 462 (89.1%) obtained a complete clinical response after one PDT treatment.
  • Laryngeal cancers, comprising 171 patients in this group, obtained a durable complete response rate of 89% with up to a 16-year follow-up.

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  • (PMID = 20552353.001).
  • [ISSN] 1940-6029
  • [Journal-full-title] Methods in molecular biology (Clifton, N.J.)
  • [ISO-abbreviation] Methods Mol. Biol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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32. Vargas PA, Speight PM, Bingle CD, Barrett AW, Bingle L: Expression of PLUNC family members in benign and malignant salivary gland tumours. Oral Dis; 2008 Oct;14(7):613-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • MATERIALS AND METHODS: A tissue microarray was assembled from 64 salivary gland tumours including adenoid cystic carcinoma, carcinoma ex-pleomorphic adenoma, mucoepidermoid carcinoma, polymorphous low-grade adenocarcinoma, pleomorphic adenoma, acinic cell carcinoma, myoepithelial carcinoma and papillary cystadenocarcinoma.
  • CONCLUSIONS: Intense expression of two PLUNC proteins in mucous cells and mucin plugs of mucoepidermoid carcinoma and papillary cystadenocarcinoma indicate that they could be used as additional diagnostic tools in some equivocal cases, but further studies are needed to understand the biological processes involved in PLUNC expression.
  • [MeSH-major] Biomarkers, Tumor. Carcinoma, Mucoepidermoid / metabolism. Cystadenocarcinoma, Papillary / metabolism. Glycoproteins / biosynthesis. Phosphoproteins / biosynthesis. Salivary Gland Neoplasms / metabolism

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  • (PMID = 18221458.001).
  • [ISSN] 1601-0825
  • [Journal-full-title] Oral diseases
  • [ISO-abbreviation] Oral Dis
  • [Language] eng
  • [Grant] United Kingdom / Wellcome Trust / / 076491; United Kingdom / Wellcome Trust / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / BPIFA1 protein, human; 0 / Biomarkers, Tumor; 0 / Glycoproteins; 0 / Phosphoproteins
  • [Other-IDs] NLM/ PMC2853704; NLM/ UKMS29166
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