[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 100 of about 426
1. Nayak SP, Walke VA, Helwatkar SB, Bobhate SK: Adenoid cystic carcinoma of the external auditory canal: report of two cases. Indian J Pathol Microbiol; 2009 Oct-Dec;52(4):540-2
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenoid cystic carcinoma of the external auditory canal: report of two cases.
  • Adenoid cystic carcinoma occurring in the external auditory canal is very rare.
  • In the second case, fine needle aspiration procedure had to be abandoned due to severe pain and a biopsy was required for its diagnosis.
  • Morphologically, it resembles its more common salivary gland counterpart.
  • Though severe pain during needling may be a limiting factor, adenoid cystic carcinoma of external auditory canal can be confidently diagnosed on cytology based on which surgical management can be planned.
  • [MeSH-major] Carcinoma, Adenoid Cystic / diagnosis. Carcinoma, Adenoid Cystic / pathology. Ear Canal / pathology

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19805967.001).
  • [ISSN] 0974-5130
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  •  go-up   go-down


2. Marques MM, Martins MD, França CM: Effect of Matrigel on adenoid cystic carcinoma cell line differentiation. Int J Exp Pathol; 2006 Dec;87(6):405-10
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of Matrigel on adenoid cystic carcinoma cell line differentiation.
  • Adenoid cystic carcinoma (ACC) is a frequent malignant salivary gland neoplasm presenting different growth patterns described as tubular, cribriform and solid, which represent distinct differentiation stages.
  • [MeSH-major] Biocompatible Materials / pharmacology. Carcinoma, Adenoid Cystic / pathology. Collagen / pharmacology. Laminin / pharmacology. Proteoglycans / pharmacology. Salivary Gland Neoplasms / pathology

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Oral Oncol. 2000 Mar;36(2):248-52 [10745180.001]
  • [Cites] Oral Oncol. 2001 Dec;37(8):638-42 [11590073.001]
  • [Cites] Virchows Arch. 2001 Oct;439(4):571-8 [11710645.001]
  • [Cites] Virchows Arch. 2002 Dec;441(6):569-76 [12461614.001]
  • [Cites] Oral Oncol. 2004 May;40(5):483-9 [15006619.001]
  • [Cites] Curr Opin Cell Biol. 1998 Oct;10(5):640-6 [9818175.001]
  • [Cites] Cancer. 1992 Jun 1;69(11):2631-40 [1315206.001]
  • [Cites] Cancer. 1992 Jul 15;70(2):379-85 [1617588.001]
  • [Cites] Cell Motil Cytoskeleton. 1995;32(4):289-98 [8608607.001]
  • [Cites] J Oral Pathol Med. 1996 Sep;25(8):441-8 [8930823.001]
  • [Cites] Virchows Arch. 1997 Jun;430(6):467-77 [9230912.001]
  • [Cites] Biochemistry. 1986 Jan 28;25(2):312-8 [2937447.001]
  • (PMID = 17222208.001).
  • [ISSN] 0959-9673
  • [Journal-full-title] International journal of experimental pathology
  • [ISO-abbreviation] Int J Exp Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biocompatible Materials; 0 / Drug Combinations; 0 / Laminin; 0 / Proteoglycans; 119978-18-6 / matrigel; 9007-34-5 / Collagen
  • [Number-of-references] 14
  • [Other-IDs] NLM/ PMC2517392
  •  go-up   go-down


3. Zhou CX, Gao Y: Aberrant expression of beta-catenin, Pin1 and cylin D1 in salivary adenoid cystic carcinoma: relation to tumor proliferation and metastasis. Oncol Rep; 2006 Sep;16(3):505-11
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Aberrant expression of beta-catenin, Pin1 and cylin D1 in salivary adenoid cystic carcinoma: relation to tumor proliferation and metastasis.
  • The aims of this study were to investigate the expression levels of beta-catenin, Pin1 and cyclin D1 in salivary adenoid cystic carcinomas (SACC ) and to evaluate its clinical importance, furthermore, to elucidate whether beta-catenin expression was aberrant in SACC and whether Pin1 was involved in aberrant beta-catenin and cyclin D1 expression.
  • [MeSH-major] Carcinoma, Adenoid Cystic / metabolism. Cyclin D1 / metabolism. Peptidylprolyl Isomerase / metabolism. Salivary Gland Neoplasms / metabolism. beta Catenin / metabolism


Advertisement
4. Ramer N, Wu H, Sabo E, Ramer Y, Emanuel P, Orta L, Burstein DE: Prognostic value of quantitative p63 immunostaining in adenoid cystic carcinoma of salivary gland assessed by computerized image analysis. Cancer; 2010 Jan 1;116(1):77-83
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Prognostic value of quantitative p63 immunostaining in adenoid cystic carcinoma of salivary gland assessed by computerized image analysis.
  • BACKGROUND: In a long-term retrospective immunohistochemical study of adenoid cystic carcinoma (ACC) of salivary gland, we investigated the relation of p63 immunodetection to prognosis.
  • CONCLUSIONS: To our knowledge, the present study is the first to report prognostic significance of p63 in salivary gland ACC and the first report of a robust and well-studied immunohistochemical stain performable on routinely fixed and processed tissue with prognostic utility.
  • [MeSH-major] Biomarkers, Tumor / analysis. Carcinoma, Adenoid Cystic / diagnosis. Membrane Proteins / analysis. Salivary Gland Neoplasms / diagnosis

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2010 American Cancer Society.
  • (PMID = 19877114.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CKAP4 protein, human; 0 / Membrane Proteins
  •  go-up   go-down


5. Zhang J, Peng B: In vitro angiogenesis and expression of nuclear factor kappaB and VEGF in high and low metastasis cell lines of salivary gland Adenoid Cystic Carcinoma. BMC Cancer; 2007;7:95
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] In vitro angiogenesis and expression of nuclear factor kappaB and VEGF in high and low metastasis cell lines of salivary gland Adenoid Cystic Carcinoma.
  • BACKGROUND: Adenoid cystic carcinoma is a high malignant carcinoma characterized by intensive local invasion and high incidence of distant metastasis.
  • Although many reports have demonstrated that angiogenesis has played an important role in tumor metastasis, the relationship between metastasis characters and angiogenesis ability in high and low metastasis cell lines of Adenoid cystic carcinoma has rarely been reported.
  • [MeSH-major] Carcinoma, Adenoid Cystic / blood supply. Carcinoma, Adenoid Cystic / secondary. Neovascularization, Pathologic / pathology. Salivary Gland Neoplasms / blood supply. Transcription Factor RelA / metabolism. Vascular Endothelial Growth Factor A / metabolism

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Biochem J. 2000 Mar 15;346 Pt 3:793-8 [10698708.001]
  • [Cites] BMC Cancer. 2006;6:110 [16650286.001]
  • [Cites] Nature. 2000 Sep 14;407(6801):249-57 [11001068.001]
  • [Cites] Cancer Res. 2000 Oct 1;60(19):5334-9 [11034066.001]
  • [Cites] Oral Oncol. 2001 Jan;37(1):77-83 [11120487.001]
  • [Cites] Cancer Res. 2001 Oct 1;61(19):7048-51 [11585733.001]
  • [Cites] Cancer. 2001 Dec 15;92(12):3037-44 [11753981.001]
  • [Cites] Breast Cancer Res Treat. 2002 Jun;73(3):237-43 [12160329.001]
  • [Cites] Biochem Pharmacol. 2002 Sep;64(5-6):883-8 [12213582.001]
  • [Cites] Cancer Res. 2002 Dec 1;62(23):6837-45 [12460896.001]
  • [Cites] FASEB J. 2002 Dec;16(14):1928-30 [12368225.001]
  • [Cites] Cell Res. 2002 Dec;12(5-6):311-20 [12528889.001]
  • [Cites] Clin Cancer Res. 2003 Jan;9(1):346-54 [12538487.001]
  • [Cites] J Biol Chem. 2003 Jun 13;278(24):21631-8 [12690099.001]
  • [Cites] Oral Oncol. 2004 Apr;40(4):400-8 [14969819.001]
  • [Cites] Nat Rev Cancer. 2004 Jun;4(6):423-36 [15170445.001]
  • [Cites] J Natl Cancer Inst. 1992 Dec 16;84(24):1875-87 [1281237.001]
  • [Cites] Eur J Cancer. 1996 Dec;32A(14):2501-5 [9059339.001]
  • [Cites] Int J Oral Maxillofac Surg. 1997 Apr;26(2):116-9 [9151166.001]
  • [Cites] Am J Surg. 1997 Nov;174(5):495-8 [9374223.001]
  • [Cites] Clin Cancer Res. 2005 Oct 15;11(20):7334-43 [16243805.001]
  • [Cites] Angiogenesis. 2005;8(4):349-60 [16400520.001]
  • [Cites] Cancer Cell. 2006 Mar;9(3):209-23 [16530705.001]
  • [Cites] J Surg Oncol. 2006 May 1;93(6):446-55 [16615157.001]
  • [Cites] Cell Signal. 2000 Mar;12(3):123-33 [10704819.001]
  • (PMID = 17543095.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Transcription Factor RelA; 0 / VEGFA protein, human; 0 / Vascular Endothelial Growth Factor A
  • [Other-IDs] NLM/ PMC1903362
  •  go-up   go-down


6. Nakashima D, Uzawa K, Kasamatsu A, Koike H, Endo Y, Saito K, Hashitani S, Numata T, Urade M, Tanzawa H: Protein expression profiling identifies maspin and stathmin as potential biomarkers of adenoid cystic carcinoma of the salivary glands. Int J Cancer; 2006 Feb 1;118(3):704-13
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Protein expression profiling identifies maspin and stathmin as potential biomarkers of adenoid cystic carcinoma of the salivary glands.
  • Adenoid cystic carcinoma (ACC) is one of the most common malignant tumors of the salivary glands.
  • It tends to grow slowly but is associated with a poor prognosis compared to other malignant salivary gland tumors.
  • To identify specific markers of ACC, we examined protein expression profiling in ACC xenograft and normal salivary glands (NSG) using fluorescent 2-dimensional differential in-gel electrophoresis (2-D-DIGE), an emerging technique for comparative proteomics, that improves the reproducibility and reliability of differential protein expression analysis between the samples.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Carcinoma, Adenoid Cystic / metabolism. Proteomics. Salivary Gland Neoplasms / metabolism. Salivary Glands / metabolism. Serpins / metabolism. Stathmin / metabolism

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2005 Wiley-Liss, Inc.
  • (PMID = 16094606.001).
  • [ISSN] 0020-7136
  • [Journal-full-title] International journal of cancer
  • [ISO-abbreviation] Int. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / SERPIN-B5; 0 / Serpins; 0 / Stathmin
  •  go-up   go-down


7. De Dosso S, Mazzucchelli L, Ghielmini M, Saletti P: Response to oxaliplatin with cetuximab in minor salivary gland adenoid cystic carcinoma. Tumori; 2009 May-Jun;95(3):378-81
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Response to oxaliplatin with cetuximab in minor salivary gland adenoid cystic carcinoma.
  • Esophageal localization of adenoid cystic carcinoma of minor salivary glands is rare; it may occur in the early to mid-sixties' age group and is more frequently encountered in men than women.
  • In the majority of cases, it arises from subepithelial glands of the middle to lower third of the esophagus, a similar distribution as squamous cell carcinoma.
  • We report a case of a patient with metastatic primary esophageal adenoid cystic carcinoma progressing on platinum- and irinotecan-based regimens, who achieved an objective response with oxaliplatin-based chemotherapy in combination with cetuximab.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinoma, Adenoid Cystic / drug therapy. Carcinoma, Adenoid Cystic / secondary. Esophageal Neoplasms / pathology. Salivary Gland Neoplasms / drug therapy. Salivary Gland Neoplasms / secondary

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Esophageal Cancer.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • Hazardous Substances Data Bank. CETUXIMAB .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19688981.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 0 / Biomarkers, Tumor; 0 / Organoplatinum Compounds; 04ZR38536J / oxaliplatin; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; PQX0D8J21J / Cetuximab
  •  go-up   go-down


8. Hara H, Oyama T, Saku T: Fine needle aspiration cytology of basal cell adenoma of the salivary gland. Acta Cytol; 2007 Sep-Oct;51(5):685-91
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fine needle aspiration cytology of basal cell adenoma of the salivary gland.
  • OBJECTIVE: To formulate cytologic features for differential diagnosis of basal cell adenoma (BCA).
  • STUDY DESIGN: The usefulness of 5 items for a cytologically definitive diagnosis of BCA was examined.
  • The 5 items in 8 BCA and 22 non-BCA cases (adenoid cystic carcinoma [ADCC], basal cell adenocarcinoma, myoepithelioma, pleomorphic adenoma and polymorphous low-grade adenocarcinoma) that displayed mimicking cytology were examined cytologically.
  • RESULTS: The useful items were < 5.1 microm in mean of epithelial nuclear short diameter; mild atypia on definitive diagnosis; stromal cell cluster combining smooth margin surrounding the epithelial cell cluster or containing the epithelial cell cluster; epithelial clusters surrounded by or adhered to a thick, hyalinized smooth margin without stromal cluster; and closely fastened, tight clusters with denser cytoplasm than ADCC, but an indistinct border, with oval nuclei and no hyaline cells.
  • [MeSH-major] Adenoma / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands / pathology
  • [MeSH-minor] Adenocarcinoma / pathology. Biopsy, Fine-Needle. Carcinoma, Adenoid Cystic / pathology. Cell Nucleus / pathology. Diagnosis, Differential. Epithelium / pathology. Epithelium / ultrastructure. Humans. Immunohistochemistry. Myoepithelioma / pathology. Organelle Size. Stromal Cells / pathology

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17910337.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  •  go-up   go-down


9. Rahman B, Mamoon N, Jamal S, Zaib N, Luqman M, Mushtaq S, Anwar M: Malignant tumors of the minor salivary glands in northern Pakistan: a clinicopathological study. Hematol Oncol Stem Cell Ther; 2008 Apr-Jun;1(2):90-3
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant tumors of the minor salivary glands in northern Pakistan: a clinicopathological study.
  • BACKGROUND: Malignant tumors of the minor salivary glands comprise a small but significant proportion of oral cancers.
  • METHODS: The records of all cases of malignant minor salivary gland tumors diagnosed at the Armed Forces Institute of Pathology (AFIP), Rawalpindi, Pakistan, during a period of 10 years (1994-2003) are described.
  • These included 70 malignant minor salivary gland tumors.
  • The commonest histological type was adenoid cystic carcinoma, constituting 30 cases (42.8%).
  • The next most common type was mucoepidermoid carcinoma comprising 26 (37.1%) cases.
  • There were 2 cases each of polymorphous low-grade adenocarcinoma and clear cell adenocarcinoma.
  • CONCLUSION: Adenoid cystic carcinoma was the commonest malignant neoplasm of the minor salivary glands followed by mucoepidermoid carcinoma.
  • [MeSH-major] Carcinoma / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands, Minor / pathology

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20063536.001).
  • [ISSN] 1658-3876
  • [Journal-full-title] Hematology/oncology and stem cell therapy
  • [ISO-abbreviation] Hematol Oncol Stem Cell Ther
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  •  go-up   go-down


10. Pogodzinski MS, Sabri AN, Lewis JE, Olsen KD: Retrospective study and review of polymorphous low-grade adenocarcinoma. Laryngoscope; 2006 Dec;116(12):2145-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Retrospective study and review of polymorphous low-grade adenocarcinoma.
  • OBJECTIVES/HYPOTHESIS: We review a single institution's experience with polymorphous low-grade adenocarcinoma.
  • To our knowledge, this is the largest patient series of polymorphous low-grade adenocarcinoma with clinical follow-up in the otolaryngology literature.
  • STUDY DESIGN: We retrospectively identified 19 patients with polymorphous low-grade adenocarcinoma who had adequate clinical follow-up and pathologic specimens available for examination.
  • The most common initial diagnoses were polymorphous low-grade adenocarcinoma, adenoid cystic carcinoma, and pleomorphic adenoma.
  • CONCLUSIONS: Polymorphous low-grade adenocarcinoma is an increasingly recognized malignancy that originates predominantly in the minor salivary gland.
  • [MeSH-major] Adenocarcinoma / pathology. Salivary Gland Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Retrospective Studies. Salivary Glands, Minor


11. Zhang J, Peng B, Chen X: Expressions of nuclear factor kappaB, inducible nitric oxide synthase, and vascular endothelial growth factor in adenoid cystic carcinoma of salivary glands: correlations with the angiogenesis and clinical outcome. Clin Cancer Res; 2005 Oct 15;11(20):7334-43
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expressions of nuclear factor kappaB, inducible nitric oxide synthase, and vascular endothelial growth factor in adenoid cystic carcinoma of salivary glands: correlations with the angiogenesis and clinical outcome.
  • OBJECTIVE: To evaluate the expressions of nuclear factor kappaB (NF-kappaB p65), inducible nitric oxide synthase enzyme (iNOS), and vascular endothelial growth factor (VEGF) in relation to angiogenesis (microvessel density, MVD) and clinical outcomes in adenoid cystic carcinoma (ACC) of salivary glands.
  • METHODS: Immunohistochemical staining was used to quantify the protein expression levels of NF-kappaB p65, iNOS, and VEGF in 80 surgically resected ACCs and 20 normal salivary tissues.
  • Both iNOS and VEGF staining activities in ACCs were more significant than those in normal gland tissues (P < 0.01).
  • [MeSH-major] Biomarkers, Tumor / biosynthesis. Carcinoma, Adenoid Cystic / pathology. Salivary Gland Neoplasms / pathology

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16243805.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Biomarkers, Tumor; 0 / Transcription Factor RelA; 0 / Vascular Endothelial Growth Factor A; EC 1.14.13.39 / Nitric Oxide Synthase Type II
  •  go-up   go-down


12. Rutherford S, Hampton GM, Frierson HF, Moskaluk CA: Mapping of candidate tumor suppressor genes on chromosome 12 in adenoid cystic carcinoma. Lab Invest; 2005 Sep;85(9):1076-85
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mapping of candidate tumor suppressor genes on chromosome 12 in adenoid cystic carcinoma.
  • Adenoid cystic carcinoma (ACC) is a common malignancy of salivary glands, for which the underlying genetic mechanisms of tumorigenesis are poorly understood.
  • [MeSH-major] Carcinoma, Adenoid Cystic / genetics. Chromosome Mapping. Chromosomes, Human, Pair 12. Genes, Tumor Suppressor. Salivary Gland Neoplasms / genetics

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16025147.001).
  • [ISSN] 0023-6837
  • [Journal-full-title] Laboratory investigation; a journal of technical methods and pathology
  • [ISO-abbreviation] Lab. Invest.
  • [Language] eng
  • [Grant] United States / NIDCR NIH HHS / DE / R01-DE-14694
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  •  go-up   go-down


13. Attlmayr B, Garrido C, Alderson DJ: Difficulty in establishing a diagnosis in an uncommon presentation of a minor salivary gland tumour. BMJ Case Rep; 2010;2010
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Difficulty in establishing a diagnosis in an uncommon presentation of a minor salivary gland tumour.
  • We report the case of a man presenting with a large, airway obstructing, minor salivary gland tumour arising from the right tonsillar base.
  • A firm diagnosis of malignancy could not be made histologically.
  • The differential diagnosis included polymorphous low-grade adenocarcinoma, basal cell adenoma and adenoid cystic carcinoma.
  • However, on balance, based on the clinical presentation, a diagnosis of malignancy was favoured and appropriate treatment was considered.
  • [MeSH-major] Adenoma / diagnosis. Adenoma / pathology. Airway Obstruction / etiology. Deglutition Disorders / etiology. Salivary Gland Neoplasms / diagnosis. Salivary Gland Neoplasms / pathology. Salivary Glands, Minor. Tongue Neoplasms / diagnosis
  • [MeSH-minor] Biomarkers, Tumor / analysis. Biopsy. Cooperative Behavior. Diagnosis, Differential. Endoscopy. Humans. Interdisciplinary Communication. Lymphatic Metastasis / pathology. Lymphatic Metastasis / radiotherapy. Magnetic Resonance Imaging. Male. Middle Aged. Palliative Care. Tongue / pathology. Tracheostomy

  • MedlinePlus Health Information. consumer health - Choking.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • MedlinePlus Health Information. consumer health - Swallowing Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Oral Dis. 2002 Sep;8(5):229-40 [12363107.001]
  • [Cites] Am J Surg. 1991 Oct;162(4):330-6 [1659242.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1996 Jun 1;35(3):443-54 [8655366.001]
  • [Cites] Cancer Treat Rev. 1996 Nov;22(6):395-423 [9134002.001]
  • [Cites] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999 Apr;87(4):485-92 [10225632.001]
  • [Cites] Ann Surg. 1956 Sep;144(3):366-83 [13363274.001]
  • [Cites] Oral Oncol. 2008 Apr;44(4):407-17 [17825603.001]
  • (PMID = 22798299.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ PMC3029651
  •  go-up   go-down


14. Marchiò C, Weigelt B, Reis-Filho JS: Adenoid cystic carcinomas of the breast and salivary glands (or 'The strange case of Dr Jekyll and Mr Hyde' of exocrine gland carcinomas). J Clin Pathol; 2010 Mar;63(3):220-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenoid cystic carcinomas of the breast and salivary glands (or 'The strange case of Dr Jekyll and Mr Hyde' of exocrine gland carcinomas).
  • Adenoid cystic carcinoma (AdCC) is a tumour with myoepithelial differentiation and characterised by the presence of a dual population of basaloid and luminal cells arranged in specific growth patterns.
  • However, the clinical behaviour of salivary gland and breast AdCC differs; while salivary gland lesions have a relatively high proclivity to metastasise, patients with breast AdCCs have an excellent outcome.
  • Here the clinical, morphological and molecular features, and potential therapeutic targets of salivary gland and breast AdCCs are reviewed.
  • [MeSH-major] Breast Neoplasms / diagnosis. Carcinoma, Adenoid Cystic / diagnosis. Salivary Gland Neoplasms / diagnosis

  • MedlinePlus Health Information. consumer health - Breast Cancer.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20203221.001).
  • [ISSN] 1472-4146
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Grant] United Kingdom / Cancer Research UK / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  • [Number-of-references] 113
  •  go-up   go-down


15. Nagliati M, Bolner A, Vanoni V, Tomio L, Lay G, Murtas R, Deidda MA, Madeddu A, Delmastro E, Verna R, Gabriele P, Amichetti M: Surgery and radiotherapy in the treatment of malignant parotid tumors: a retrospective multicenter study. Tumori; 2009 Jul-Aug;95(4):442-8
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • AIMS AND BACKGROUND: Major salivary gland cancers are rare, with many histologic types and subtypes.
  • The most frequent histologies were adenoid cystic carcinoma (n = 16), mucoepidermoid carcinoma (n = 15), and acinic cell carcinoma (n = 15).
  • CONCLUSIONS: The treatment of salivary gland malignancies remains primarily surgical.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19856654.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
  •  go-up   go-down


16. Guo XL, Wei FC, Sun SZ: [Clinical study of oral and maxillofacial malignancies associated with multiple primary malignant neoplasms]. Hua Xi Kou Qiang Yi Xue Za Zhi; 2006 Feb;24(1):42-4
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To study the clinical characteristics, diagnosis and treatment strategy of oral and maxillofacial malignancies in multiple primary malignant neoplasms (MPMNs).
  • Among the 44 cases, there were 24 cases in alimentary and respiratory tract such as oral, pharynx, esophagus, stomach and lung, and 10 cases in salivary gland, breast and female reproductive system.
  • There were 25 cases malignant neoplasms in oral and maxillofacial region where squamous cell carcinoma was the most common pathologic type, secondly adenoid cystic carcinoma.
  • In oral and maxillofacial region, MPMNs were often found in tongue, parotid and submandibular gland, buccal mucosa and gingival.
  • CONCLUSION: Tongue and salivary gland were the common locations with MPMNs, and they were closely associated with alimentary and respiratory tract.
  • Regular follow-up, early detection, early diagnosis, active and effective treatment can help to improve the survival quality of MPMNs patients.
  • [MeSH-major] Carcinoma, Adenoid Cystic. Carcinoma, Squamous Cell. Mouth Neoplasms. Neoplasms, Multiple Primary

  • MedlinePlus Health Information. consumer health - Oral Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16541654.001).
  • [ISSN] 1000-1182
  • [Journal-full-title] Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology
  • [ISO-abbreviation] Hua Xi Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  •  go-up   go-down


17. Whitt JC, Schafer DR, Callihan MD: Multiple malignant salivary gland neoplasms: mucoepidermoid carcinoma of palate and adenoid cystic carcinoma of floor of mouth. Head Neck Pathol; 2008 Mar;2(1):41-8
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multiple malignant salivary gland neoplasms: mucoepidermoid carcinoma of palate and adenoid cystic carcinoma of floor of mouth.
  • Salivary gland tumors usually occur as single lesions.
  • We report a case of an adult male who presented with a mucoepidermoid carcinoma involving the minor salivary glands of the palate at age 57 years, followed by an adenoid cystic carcinoma of the floor of mouth at age 63 years.
  • There are 31 acceptable cases of multiple malignant salivary gland neoplasms reported in the world literature.
  • Bilateral acinic cell adenocarcinoma was the most frequent combination of multiple salivary gland malignancy, accounting for 14 cases (10 synchronous and four metachronous).
  • All involved the parotid glands bilaterally with the exception of one case that involved parotid and submandibular gland.
  • Polymorphous low-grade adenocarcinoma accounted for three of the four cases of multiple malignant tumors involving minor salivary glands.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Carcinoma, Mucoepidermoid / pathology. Mouth Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Palatal Neoplasms / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands, Minor / pathology

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • Genetic Alliance. consumer health - Mucoepidermoid carcinoma.
  • MedlinePlus Health Information. consumer health - Oral Cancer.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Oral Surg Oral Med Oral Pathol. 1988 Aug;66(2):179-83 [3050706.001]
  • [Cites] Head Neck. 2005 Sep;27(9):825-8 [15920750.001]
  • [Cites] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001 Apr;91(4):455-61 [11312463.001]
  • [Cites] Ann Surg. 1969 Nov;170(5):866-9 [5347563.001]
  • [Cites] Surg Gynecol Obstet. 1974 Jan;138(1):65-8 [4809004.001]
  • [Cites] Sem Hop. 1973 Jun 14;49(28):2031-3 [4359568.001]
  • [Cites] Am J Clin Pathol. 1974 Feb;61(2):270-4 [4811743.001]
  • [Cites] Arch Surg. 1975 Jan;110(1):64-8 [1090282.001]
  • [Cites] Oral Surg Oral Med Oral Pathol. 1976 Jun;41(6):764-71 [179038.001]
  • [Cites] Tumori. 1975 Jan-Feb;61(1):39-43 [179172.001]
  • [Cites] Cancer. 1976 Dec;38(6):2462-8 [1000476.001]
  • [Cites] Ann Surg. 1976 Oct;184(4):500-6 [1015893.001]
  • [Cites] Ann Intern Med. 1977 Aug;87(2):160-4 [889197.001]
  • [Cites] Laryngol Rhinol Otol (Stuttg). 1977 Nov;56(11):907-11 [201812.001]
  • [Cites] Cancer. 1978 Mar;41(3):924-35 [638978.001]
  • [Cites] Laryngoscope. 1978 Dec;88(12):1935-41 [732494.001]
  • [Cites] ORL J Otorhinolaryngol Relat Spec. 1978;40(2):120-6 [570688.001]
  • [Cites] Plast Reconstr Surg. 1980 May;65(5):676-8 [6245420.001]
  • [Cites] Am J Pathol. 1982 Oct;109(1):129-32 [6289671.001]
  • [Cites] Cancer. 1983 Jun 15;51(12):2159-63 [6850504.001]
  • [Cites] J Laryngol Otol. 1985 Nov;99(11):1183-93 [4056607.001]
  • [Cites] Hum Pathol. 1986 Sep;17(9):914-23 [3759075.001]
  • [Cites] J Natl Cancer Inst. 1988 Aug 17;80(12):943-9 [3398070.001]
  • [Cites] Cancer. 1989 Mar 15;63(6):1219-24 [2917323.001]
  • [Cites] Br J Oral Maxillofac Surg. 1989 Jun;27(3):192-7 [2663053.001]
  • [Cites] Ann Pathol. 1989;9(5):351-4 [2558664.001]
  • [Cites] J Laryngol Otol. 1991 Sep;105(9):796-8 [1919360.001]
  • [Cites] Br J Surg. 1992 Sep;79(9):928-30 [1422760.001]
  • [Cites] Community Dent Oral Epidemiol. 1992 Oct;20(5):284-7 [1424549.001]
  • [Cites] Am J Surg. 1992 Dec;164(6):646-7 [1334381.001]
  • [Cites] J Oral Pathol Med. 1993 Sep;22(8):348-53 [8283400.001]
  • [Cites] J Laryngol Otol. 1994 Sep;108(9):798-800 [7964150.001]
  • [Cites] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995 Jul;80(1):71-7 [7552866.001]
  • [Cites] Eur J Cancer B Oral Oncol. 1996 Jan;32B(1):3-7 [8729611.001]
  • [Cites] Oral Oncol. 1997 Jul;33(4):284-7 [9307720.001]
  • [Cites] Virchows Arch. 1999 Apr;434(4):361-5 [10335948.001]
  • [Cites] J Laryngol Otol. 2003 May;117(5):419-21 [12803799.001]
  • [Cites] Ann Otol Rhinol Laryngol. 1966 Sep;75(3):780-92 [5917646.001]
  • [Cites] Arch Pathol Lab Med. 1999 Nov;123(11):1118-20 [10539921.001]
  • [Cites] Am J Surg. 1969 Nov;118(5):787-9 [4310431.001]
  • [Cites] AMA Arch Pathol. 1953 Apr;55(4):328-46 [13030050.001]
  • [Cites] Plast Reconstr Surg Transplant Bull. 1959 Jan;23(1):55-63 [13633480.001]
  • [Cites] J Laryngol Otol. 1961 Jul;75:699-702 [13722582.001]
  • [Cites] Acta Otolaryngol Suppl. 1964;188:SUPPL 191:1-99 [14156485.001]
  • [Cites] Cancer. 1966 Sep;19(9):1308-10 [5919065.001]
  • (PMID = 20614341.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2807610
  • [Keywords] NOTNLM ; Metachronous neoplasms / Multiple malignant salivary gland neoplasms / Salivary gland neoplasms / Salivary gland tumors / Synchronous neoplasms
  •  go-up   go-down


18. Luo SD, Su CY, Chuang HC, Huang CC, Chen CM, Chien CY: Estrogen receptor overexpression in malignant minor salivary gland tumors of the sinonasal tract. Otolaryngol Head Neck Surg; 2009 Jul;141(1):108-13
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Estrogen receptor overexpression in malignant minor salivary gland tumors of the sinonasal tract.
  • OBJECTIVES: To identify the expression of estrogen receptors in malignant minor salivary gland tumors of the sinonasal tract.
  • SUBJECTS AND METHODS: A retrospective review of a pathology database identified 17 patients with malignant salivary gland tumors between December 1987 and January 2006.
  • RESULTS: Among these malignant tumors, adenoid cystic carcinoma was the predominant histologic type.
  • Seventy-five percent of cases of adenoid cystic carcinoma were positive for estrogen receptor alpha.
  • In contrast, only 17 percent of cases of adenoid cystic carcinoma were positive for estrogen receptor beta.
  • CONCLUSION: Malignant minor salivary gland tumors of the sinonasal tract are rare disease entities.
  • In the present series, adenoid cystic carcinoma was the most common form of tumor, but the prognosis was poor.
  • Most of the cases were positive for expression of estrogen receptor alpha, which suggests that hormone therapy may have a role in the management of certain minor salivary gland tumors of the paranasal sinus and nasal cavity.
  • [MeSH-major] Paranasal Sinus Neoplasms / metabolism. Receptors, Estrogen / metabolism. Salivary Gland Neoplasms / metabolism

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19559968.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, Estrogen
  •  go-up   go-down


19. Zhao JF, Li XM, Xie WH, Wang HB, Fang Z, Li QC: [Effect and mechanism of matrine on adhesion and invasion of salivary gland adenoid cystic carcinoma cells in vitro]. Shanghai Kou Qiang Yi Xue; 2009 Aug;18(4):401-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Effect and mechanism of matrine on adhesion and invasion of salivary gland adenoid cystic carcinoma cells in vitro].
  • PURPOSE: To investigate the effect and mechanism of matrine on adhesion and invasion of human adenoid cystic carcinoma ACC-M cells in vitro.
  • [MeSH-major] Carcinoma, Adenoid Cystic. Cell Line, Tumor
  • [MeSH-minor] Alkaloids. Cell Adhesion. Humans. In Vitro Techniques. Quinolizines. Salivary Gland Neoplasms. Salivary Glands

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19760015.001).
  • [ISSN] 1006-7248
  • [Journal-full-title] Shanghai kou qiang yi xue = Shanghai journal of stomatology
  • [ISO-abbreviation] Shanghai Kou Qiang Yi Xue
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Alkaloids; 0 / Quinolizines; 519-02-8 / matrine
  •  go-up   go-down


20. Chen W, Zhang HL, Shao XJ, Jiang YG, Zhao XG, Gao X, Li JH, Yang J, Zhang YF, Liu BL, Sun MY: Gene expression profile of salivary adenoid cystic carcinoma associated with perineural invasion. Tohoku J Exp Med; 2007 Jul;212(3):319-34
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gene expression profile of salivary adenoid cystic carcinoma associated with perineural invasion.
  • Adenoid cystic carcinoma (ACC) is a common salivary gland malignancy characterized by slow but progressive clinical course, proclivity for hematogenous spread and perineural invasion (PNI) that exhibits inherent resistance to complete surgical resection, systemic chemotherapy and conventional radiotherapy.
  • We report the combined use of laser capture microdissection (LCM) and high-throughput cDNA microarray to monitor in vivo gene expression profile of salivary ACC and to correlate the profile with PNI.
  • Pure cancer cells adjacent to the nerve tracts from 6 cancerous tissues judged as PNI were laser captured, and pure cancer cells from the same 6 tumors distant from the nerve tracts were also procured.
  • As to the result of 6 arrays, a total of 53 genes were identified as being 2-fold or more differentially expressed in PNI cancer cell group as compared to non-PNI cancer cell control.
  • The combined use of LCM and cDNA microarray analysis provides a powerful new approach to monitor the in vivo molecular events of PNI in salivary ACC.
  • [MeSH-major] Carcinoma, Adenoid Cystic / genetics. Carcinoma, Adenoid Cystic / pathology. Gene Expression Profiling. Peripheral Nervous System Neoplasms / genetics. Peripheral Nervous System Neoplasms / pathology. Salivary Gland Neoplasms / genetics. Salivary Gland Neoplasms / pathology

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17592219.001).
  • [ISSN] 0040-8727
  • [Journal-full-title] The Tohoku journal of experimental medicine
  • [ISO-abbreviation] Tohoku J. Exp. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Validation Studies
  • [Publication-country] Japan
  •  go-up   go-down


21. Pontes FS, Ferrazzo KL, dos Santos Pinto-Júnior D: Unusual presentation of adenoid cystic carcinoma mimicking a dentoalveolar fistula. Br J Oral Maxillofac Surg; 2007 Oct;45(7):597
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unusual presentation of adenoid cystic carcinoma mimicking a dentoalveolar fistula.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Mandibular Neoplasms / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands, Minor / pathology
  • [MeSH-minor] Adult. Dental Fistula / diagnosis. Diagnosis, Differential. Female. Humans

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17507122.001).
  • [ISSN] 0266-4356
  • [Journal-full-title] The British journal of oral & maxillofacial surgery
  • [ISO-abbreviation] Br J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
  •  go-up   go-down


22. Costa AF, Demasi AP, Bonfitto VL, Bonfitto JF, Furuse C, Araújo VC, Metze K, Altemani A: Angiogenesis in salivary carcinomas with and without myoepithelial differentiation. Virchows Arch; 2008 Oct;453(4):359-67
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiogenesis in salivary carcinomas with and without myoepithelial differentiation.
  • To investigate whether salivary carcinomas with and without myoepithelial differentiation could present differences regarding degree of angiogenesis, we compared tumor vascularization between adenoid cystic (31 cases) and epithelial-myoepithelial carcinomas (14) versus mucoepidermoid (37) carcinoma.
  • The reasons for this lower angiogenic activity remain to be determined but could be related to metabolic characteristics of the cancer cells.
  • [MeSH-major] Neovascularization, Pathologic / pathology. Salivary Gland Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Antigens, CD / metabolism. Antigens, CD34 / metabolism. Carcinoma, Adenoid Cystic / pathology. Carcinoma, Mucoepidermoid / pathology. Cell Differentiation. Endoglin. Female. Humans. Male. Middle Aged. Myoepithelioma / pathology. Receptors, Cell Surface / metabolism

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Mammary Gland Biol Neoplasia. 2005 Jul;10(3):249-60 [16807804.001]
  • [Cites] J Natl Cancer Inst. 2002 Jun 19;94(12):883-93 [12072542.001]
  • [Cites] Cancer Metastasis Rev. 1990 Nov;9(3):171-4 [1705485.001]
  • [Cites] Int J Surg Pathol. 2005 Jan;13(1):57-65 [15735856.001]
  • [Cites] J Biol Chem. 1999 Jan 8;274(2):584-94 [9872992.001]
  • [Cites] Virchows Arch. 2007 Jul;451(1):65-71 [17593387.001]
  • [Cites] Anticancer Res. 2001 Nov-Dec;21(6B):4311-6 [11908685.001]
  • [Cites] Prog Histochem Cytochem. 2003;38(4):343-426 [14509196.001]
  • [Cites] FASEB J. 2003 Jun;17 (9):984-92 [12773481.001]
  • [Cites] Hum Pathol. 2006 Jul;37(7):861-6 [16784986.001]
  • [Cites] J Cell Sci. 2003 Jul 1;116(Pt 13):2677-85 [12746487.001]
  • [Cites] Semin Cancer Biol. 2003 Apr;13(2):159-67 [12654259.001]
  • [Cites] J Pathol. 1996 Apr;178(4):363-6 [8691311.001]
  • [Cites] Cancer Res. 1994 Jul 1;54(13):3333-6 [8012945.001]
  • [Cites] Nature. 2000 Nov 9;408(6809):239-47 [11089981.001]
  • [Cites] Br J Cancer. 2000 Feb;82(4):844-51 [10732757.001]
  • [Cites] BMC Cancer. 2006 May 02;6:110 [16650286.001]
  • [Cites] World J Gastroenterol. 2003 Jun;9(6):1144-55 [12800214.001]
  • [Cites] J Cell Physiol. 2001 Jul;188(1):1-7 [11382917.001]
  • [Cites] J Clin Pathol. 1998 Jul;51(7):506-11 [9797726.001]
  • [Cites] APMIS. 2004 Jul-Aug;112(7-8):413-30 [15563306.001]
  • [Cites] Oncogene. 2000 Jul 20;19(31):3449-59 [10918603.001]
  • [Cites] Nat Biotechnol. 1997 Aug;15(8):778-83 [9255794.001]
  • [Cites] Science. 2003 Apr 25;300(5619):650-3 [12714747.001]
  • [Cites] J Surg Oncol. 2006 May 1;93(6):446-55 [16615157.001]
  • [Cites] Anticancer Res. 1998 Sep-Oct;18(5A):3621-8 [9858949.001]
  • [Cites] Int J Cancer. 1993 May 28;54(3):363-70 [8509210.001]
  • [Cites] J Clin Oncol. 1995 Mar;13(3):765-82 [7533829.001]
  • [Cites] BMC Cancer. 2007 Jun 01;7:95 [17543095.001]
  • [Cites] Microsc Res Tech. 2001 Feb 15;52(4):437-49 [11170303.001]
  • (PMID = 18795324.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD34; 0 / ENG protein, human; 0 / Endoglin; 0 / Receptors, Cell Surface
  •  go-up   go-down


23. Adeyemo WL, Ajayi OF, Anunobi CC, Ogunlewe MO, Ladeinde AL, Omitola OG, Abdulkareem FB: Tumours of the submandibular salivary gland: a clinicopathologic review of cases over a 17-year period. West Indian Med J; 2009 Sep;58(4):388-91
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tumours of the submandibular salivary gland: a clinicopathologic review of cases over a 17-year period.
  • OBJECTIVE: This study presents a clinicopathologic review of cases of submandibular salivary gland tumours at the Lagos University Teaching Hospital, Nigeria, over a period of 17 years.
  • METHODS: The records of all patients with histological diagnosis of submandibular salivary gland tumours at the Lagos University Teaching Hospital over a period of 17 years (January 1990 to December 2006) were retrospectively reviewed.
  • Parameters studied were; age and gender of patients, symptoms and duration of symptoms, and histological diagnosis.
  • RESULTS: A total of 36 patients with submandibular gland tumours were seen during the period.
  • Pleomorphic adenoma (36.1%) was the most frequent tumours, followed by adenoid cystic carcinoma (11.1%), anaplastic carcinoma (11.1%) and malignant lymphoma (11.1%).
  • Patients with histological diagnosis of malignant tumours were significantly older than those with benign tumours (p = 0.01).
  • CONCLUSION: Malignant submandibular salivary gland tumours were slightly more than the benign ones in the studied population.
  • Painful swelling or ulceration is indicative of a malignant submandibular gland tumour
  • [MeSH-major] Submandibular Gland Neoplasms / diagnosis
  • [MeSH-minor] Adenoma, Pleomorphic / diagnosis. Adenoma, Pleomorphic / pathology. Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma / diagnosis. Carcinoma / pathology. Carcinoma, Adenoid Cystic / diagnosis. Carcinoma, Adenoid Cystic / pathology. Female. Humans. Lymphoma / diagnosis. Lymphoma / pathology. Male. Middle Aged. Retrospective Studies. Young Adult

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20099784.001).
  • [ISSN] 0043-3144
  • [Journal-full-title] The West Indian medical journal
  • [ISO-abbreviation] West Indian Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Jamaica
  •  go-up   go-down


24. Dahse R, Driemel O, Schwarz S, Kromeyer-Hauschild K, Berndt A, Kosmehl H: KRAS status and epidermal growth factor receptor expression as determinants for anti-EGFR therapies in salivary gland carcinomas. Oral Oncol; 2009 Sep;45(9):826-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] KRAS status and epidermal growth factor receptor expression as determinants for anti-EGFR therapies in salivary gland carcinomas.
  • Salivary gland carcinomas (SGC) are rare cancers with poor prognosis and limited response to conventional chemotherapy.
  • KRAS mutation analysis was performed by direct genomic sequencing and revealed a KRAS wildtype in 98.5% except of one adenoid cystic carcinoma with a GGT-GAT transition at codon 12 (Gly12Asp).
  • [MeSH-major] Carcinoma. Genes, ras / genetics. Neoplasm Proteins. Receptor, Epidermal Growth Factor / metabolism. Salivary Gland Neoplasms


25. de Lima Mde D, Marques YM, Alves Sde M Jr, Freitas VM, Soares FA, de Araújo VC, Pinto Ddos S Jr, Mantesso A: MDM2, P53, P21WAF1 and pAKT protein levels in genesis and behaviour of adenoid cystic carcinoma. Cancer Epidemiol; 2009 Aug;33(2):142-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] MDM2, P53, P21WAF1 and pAKT protein levels in genesis and behaviour of adenoid cystic carcinoma.
  • There are many hypotheses regarding the role of these proteins in salivary gland tumours.
  • The aim of this study was to evaluate and to correlate MDM2, P53, P21(WAF1) and pAKT protein expressions in adenoid cystic carcinomas (ACC).
  • [MeSH-major] Carcinoma, Adenoid Cystic / metabolism. Cyclin-Dependent Kinase Inhibitor p21 / metabolism. Proto-Oncogene Proteins c-akt / metabolism. Proto-Oncogene Proteins c-mdm2 / metabolism. Salivary Gland Neoplasms / metabolism. Tumor Suppressor Protein p53 / metabolism
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Blotting, Western. Case-Control Studies. Fluorescent Antibody Technique. Humans. Immunoenzyme Techniques. Salivary Glands / metabolism. Salivary Glands / pathology. Tumor Cells, Cultured

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19679062.001).
  • [ISSN] 1877-783X
  • [Journal-full-title] Cancer epidemiology
  • [ISO-abbreviation] Cancer Epidemiol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CDKN1A protein, human; 0 / Cyclin-Dependent Kinase Inhibitor p21; 0 / TP53 protein, human; 0 / Tumor Suppressor Protein p53; EC 2.7.11.1 / Proto-Oncogene Proteins c-akt; EC 6.3.2.19 / MDM2 protein, human; EC 6.3.2.19 / Proto-Oncogene Proteins c-mdm2
  •  go-up   go-down


26. Jiang J, Tang Y, Zhu G, Zheng M, Yang J, Liang X: Correlation between transcription factor Snail1 expression and prognosis in adenoid cystic carcinoma of salivary gland. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Dec;110(6):764-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Correlation between transcription factor Snail1 expression and prognosis in adenoid cystic carcinoma of salivary gland.
  • The aim of the present study was to study the association of Snail1 expression with clinicopathologic factors and prognosis in adenoid cystic carcinoma (ACC) of salivary gland.
  • STUDY DESIGN: Demographic variables and primary tumor site, dates of diagnoses, perineural invasion, local regional recurrence, and distant metastasis of 121 cases of salivary ACC were retrieved.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Gene Expression Regulation, Neoplastic / genetics. Salivary Gland Neoplasms / pathology. Transcription Factors / analysis. Zinc Fingers / genetics
  • [MeSH-minor] Epithelial-Mesenchymal Transition / genetics. Female. Follow-Up Studies. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Recurrence, Local / pathology. Prognosis. Salivary Glands / pathology. Survival Rate. Treatment Outcome

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2010 Mosby, Inc. All rights reserved.
  • (PMID = 20952218.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Transcription Factors; 0 / snail family transcription factors
  •  go-up   go-down


27. Fukuda M, Horiuchi Y, Oku Y, Ishikawa M, Suka N, Suzuki S, Kusama K, Sakashita H: Induction of apoptosis in human salivary gland tumor cells by anti-NCAM antibody. Oncol Rep; 2005 Nov;14(5):1143-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Induction of apoptosis in human salivary gland tumor cells by anti-NCAM antibody.
  • It has been reported that NCAM may be associated with perineural invasion by malignant salivary gland tumors such as adenoid cystic carcinoma.
  • We have previously demonstrated that NCAM is constitutively expressed in the human salivary gland tumor cell line HSG, in vitro.
  • In the present study, we have aimed to clarify the hypothesis that NCAM-mediated inhibition of salivary gland tumor proliferation is caused by homophilic binding and involves the prevention of signal transduction for perineural invasion using HSG cells.
  • In addition, the localization of NCAM in adenoid cystic carcinomas (ACCs) was examined using an immunohistochemical method.
  • These findings suggest that NCAM is associated not only with a cell-to-cell adhesion mechanism, but also with tumorigenesis, including growth, development and perineural invasion in human salivary gland tumors.
  • [MeSH-major] Apoptosis / immunology. Neural Cell Adhesion Molecules / biosynthesis. Neural Cell Adhesion Molecules / immunology. Salivary Gland Neoplasms / immunology. Salivary Gland Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16211277.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Antibodies; 0 / Neural Cell Adhesion Molecules; 0 / RNA, Messenger; EC 3.4.22.- / Caspases
  •  go-up   go-down


28. Locati LD, Perrone F, Losa M, Mela M, Casieri P, Orsenigo M, Cortelazzi B, Negri T, Tamborini E, Quattrone P, Bossi P, Rinaldi G, Bergamini C, Calderone RG, Liberatoscioli C, Licitra L: Treatment relevant target immunophenotyping of 139 salivary gland carcinomas (SGCs). Oral Oncol; 2009 Nov;45(11):986-90
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Treatment relevant target immunophenotyping of 139 salivary gland carcinomas (SGCs).
  • Salivary gland carcinomas (SGCs) are rare tumors encompassing a wide spectrum of histologic/biologic entities.
  • EGFR was the most expressed TKRs (71%) and it was found across all histotypes. c-Kit expression was mainly restricted to adenoid cystic carcinoma (78%) while HER2 expression, mostly sustained by gene amplification, correlated with salivary duct carcinoma (SDC) in 44% of cases and adenocarcinoma, not otherwise specified (AD, NOS) in 21% of cases.
  • AR was found in 13% of samples, restricted to SDC and AD, NOS and it was co-expressed with HER2 in more than half of the SDC cases.
  • [MeSH-major] Carcinoma / metabolism. Receptor Protein-Tyrosine Kinases / metabolism. Receptors, Steroid / metabolism. Salivary Gland Neoplasms / metabolism
  • [MeSH-minor] Adenocarcinoma / metabolism. Humans. Immunophenotyping. In Situ Hybridization, Fluorescence. Retrospective Studies


29. Zhao DM, He HW, Liu MY, He ZX: [Tumors of different histological type in unilateral salivary glands: a case report]. Hua Xi Kou Qiang Yi Xue Za Zhi; 2010 Dec;28(6):680-1, 683
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Tumors of different histological type in unilateral salivary glands: a case report].
  • Tumors of synchronous benign and malignant in unilateral salivary glands have rarely been reported.
  • A case of 21-year-old girl who was diagnosed as synchronously adenoid cystic carcinoma of the left parotid and pleomorphic adenoma of the left submandibular gland.
  • The classification, clinic pathology, diagnosis, possible mechanism were discussed based on similar literatures.
  • [MeSH-major] Adenoma, Pleomorphic. Carcinoma, Adenoid Cystic
  • [MeSH-minor] Female. Humans. Salivary Glands. Young Adult

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21365854.001).
  • [ISSN] 1000-1182
  • [Journal-full-title] Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology
  • [ISO-abbreviation] Hua Xi Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] China
  •  go-up   go-down


30. Qing J, Zhang Q, Wei MW, Guo ZM: [Prognostic analysis of adenoid cystic carcinoma of major salivary glands of 64 cases]. Ai Zheng; 2006 Sep;25(9):1138-43
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Prognostic analysis of adenoid cystic carcinoma of major salivary glands of 64 cases].
  • BACKGROUND & OBJECTIVE: Adenoid cystic carcinoma of salivary glands is a kind of highly malignant tumor, and researches on the tumors originated from major salivary glands are rare.
  • This study was to investigate prognostic factors of adenoid cystic carcinoma of major salivary glands.
  • METHODS: Clinical records of 64 patients with adenoid cystic carcinoma of major salivary glands followed up for more than 7 years were reviewed.
  • CONCLUSION: Presence or absence of nerve invasion, histological subtype, clinical stage, and positive or negative surgical margin are the independent factors affecting the prognosis of patients with adenoid cystic carcinoma of salivary glands.
  • [MeSH-major] Carcinoma, Adenoid Cystic / secondary. Lung Neoplasms / secondary. Salivary Gland Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Age Factors. Aged. Female. Humans. Lymphatic Metastasis. Male. Middle Aged. Multivariate Analysis. Neoplasm Invasiveness. Neoplasm Staging. Parotid Neoplasms / mortality. Parotid Neoplasms / pathology. Parotid Neoplasms / therapy. Prognosis. Radiotherapy, Adjuvant. Submandibular Gland Neoplasms / mortality. Submandibular Gland Neoplasms / pathology. Submandibular Gland Neoplasms / therapy. Survival Rate


31. Freier K, Flechtenmacher C, Walch A, Devens F, Mühling J, Lichter P, Joos S, Hofele C: Differential KIT expression in histological subtypes of adenoid cystic carcinoma (ACC) of the salivary gland. Oral Oncol; 2005 Oct;41(9):934-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Differential KIT expression in histological subtypes of adenoid cystic carcinoma (ACC) of the salivary gland.
  • Adenoid cystic carcinoma (ACC) of the salivary gland is characterized by a prolonged but inevitably unfavorable clinical course.
  • [MeSH-major] Carcinoma, Adenoid Cystic / metabolism. Proto-Oncogene Proteins c-kit / metabolism. Salivary Gland Neoplasms / metabolism

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16054424.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
  •  go-up   go-down


32. Papadas T, Chorianopoulos D, Mastronikolis N: Nasopharyngeal adenoid cystic carcinoma: a rare nasopharyngeal tumor. Eur Rev Med Pharmacol Sci; 2007 Jan-Feb;11(1):55-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nasopharyngeal adenoid cystic carcinoma: a rare nasopharyngeal tumor.
  • Adenoid cystic carcinoma (ACC) is the most common histologic subtype of the salivary gland malignancies, but it is very rare in the nasopharynx with relatively few cases reported in the literature.
  • [MeSH-major] Carcinoma, Adenoid Cystic / therapy. Nasopharyngeal Neoplasms / therapy

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • Genetic Alliance. consumer health - Nasopharyngeal carcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17405348.001).
  • [ISSN] 1128-3602
  • [Journal-full-title] European review for medical and pharmacological sciences
  • [ISO-abbreviation] Eur Rev Med Pharmacol Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


33. Wenghoefer M, Pantelis A, Dommisch H, Götz W, Reich R, Bergé S, Martini M, Allam JP, Jepsen S, Merkelbach-Bruse S, Fischer HP, Novak N, Winter J: Nuclear hBD-1 accumulation in malignant salivary gland tumours. BMC Cancer; 2008;8:290
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nuclear hBD-1 accumulation in malignant salivary gland tumours.
  • Therefore this study was conducted to characterise proteins involved in cell cycle control and host defence in different benign and malignant salivary gland tumours in comparison with healthy salivary gland tissue.
  • METHODS: 21 paraffin-embedded tissue samples of benign (n = 7), and malignant (n = 7) salivary gland tumours as well as healthy (n = 7) salivary glands were examined immunohistochemically for the expression of p53, bcl-2, and hBD-1, -2, -3.
  • RESULTS: HBD-1 was distributed in the cytoplasm of healthy salivary glands and benign salivary gland tumours but seems to migrate into the nucleus of malignant salivary gland tumours.
  • CONCLUSION: HBD-1, 2 and 3 are traceable in healthy salivary gland tissue as well as in benign and malignant salivary gland tumours.
  • As hBD-1 is shifted from the cytoplasm to the nucleus in malignant salivary gland tumours, we hypothesize that it might play a role in the oncogenesis of these tumours.
  • [MeSH-major] Cell Nucleus / metabolism. Salivary Gland Neoplasms / metabolism. beta-Defensins / metabolism
  • [MeSH-minor] Adenoma, Pleomorphic / metabolism. Carcinoma, Adenoid Cystic / metabolism. Case-Control Studies. Cytoplasm / metabolism. Female. Gene Expression. Humans. Immunohistochemistry. Male. Middle Aged. Proto-Oncogene Proteins c-bcl-2 / metabolism. Salivary Glands / metabolism. Salivary Glands / pathology. Tumor Suppressor Protein p53 / metabolism

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Oncogene. 2000 Jan 20;19(3):373-9 [10656684.001]
  • [Cites] Int J Oral Maxillofac Surg. 2008 Jul;37(7):660-3 [18346877.001]
  • [Cites] Eur J Oral Sci. 2002 Apr;110(2):121-4 [12013554.001]
  • [Cites] Lab Invest. 2003 Apr;83(4):501-5 [12695553.001]
  • [Cites] Science. 1991 Jul 5;253(5015):49-53 [1905840.001]
  • [Cites] Nature. 1991 Jul 25;352(6333):345-7 [1852210.001]
  • [Cites] Cell. 1992 Nov 13;71(4):543-6 [1423612.001]
  • [Cites] Cell. 1993 Sep 24;74(6):957-67 [8402885.001]
  • [Cites] Oncogene. 1994 Jun;9(6):1791-8 [8183578.001]
  • [Cites] Oncogene. 1994 Jun;9(6):1799-805 [8183579.001]
  • [Cites] EMBO J. 1996 Jul 15;15(14):3693-701 [8758936.001]
  • [Cites] Oncogene. 1999 May 13;18(19):3004-16 [10378696.001]
  • [Cites] Oral Microbiol Immunol. 2005 Jun;20(3):163-6 [15836517.001]
  • [Cites] Oral Microbiol Immunol. 2005 Jun;20(3):186-90 [15836521.001]
  • [Cites] Cancer. 2005 Jun 15;103(12):2526-33 [15900577.001]
  • [Cites] Arthritis Rheum. 2005 Jun;52(6):1736-45 [15934078.001]
  • [Cites] Pathologe. 2005 Sep;26(5):345-52 [16049672.001]
  • [Cites] Cell Microbiol. 2005 Oct;7(10):1387-97 [16153239.001]
  • [Cites] Ann Anat. 2005 Nov;187(5-6):499-508 [16320829.001]
  • [Cites] J Pathol. 2006 Jun;209(2):166-73 [16622898.001]
  • [Cites] Med Oral Patol Oral Cir Bucal. 2006 Aug;11(5):E446-8 [16878064.001]
  • [Cites] AJNR Am J Neuroradiol. 2006 Aug;27(7):1483-5 [16908563.001]
  • [Cites] Cancer Res. 2006 Sep 1;66(17):8542-9 [16951166.001]
  • [Cites] Int J Cancer. 2006 Nov 15;119(10):2247-54 [16921484.001]
  • [Cites] Mol Immunol. 2008 Jun;45(11):3163-7 [18433872.001]
  • [Cites] Anticancer Res. 2000 Mar-Apr;20(2B):1125-7 [10810407.001]
  • (PMID = 18840281.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DEFB1 protein, human; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / Tumor Suppressor Protein p53; 0 / beta-Defensins
  • [Other-IDs] NLM/ PMC2567991
  •  go-up   go-down


34. Hara S, Nakashiro K, Goda H, Hamakawa H: Role of Akt isoforms in HGF-induced invasive growth of human salivary gland cancer cells. Biochem Biophys Res Commun; 2008 May 23;370(1):123-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Role of Akt isoforms in HGF-induced invasive growth of human salivary gland cancer cells.
  • A recent study demonstrated HGF and c-Met expression in human salivary gland cancer tissues.
  • Here, we investigated the role of the HGF/c-Met system in the invasive growth of two human salivary gland cancer cell lines: green fluorescent protein-adenoid cystic carcinoma 2 (GFP-ACC2) and GFP-ACCM.
  • Our findings suggest that all of the Akt isoforms are required for the HGF-stimulated invasive growth of human salivary gland cancer cells, and that targeting a single Akt isoform could be effective in treating salivary gland cancers.
  • [MeSH-major] Carcinoma, Adenoid Cystic / enzymology. Carcinoma, Adenoid Cystic / pathology. Proto-Oncogene Proteins c-akt / metabolism. Salivary Gland Neoplasms / enzymology. Salivary Gland Neoplasms / pathology


35. Ward BK, Seethala RR, Barnes EL, Lai SY: Basal cell adenocarcinoma of a hard palate minor salivary gland: case report and review of the literature. Head Neck Oncol; 2009 Dec 23;1:41
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Basal cell adenocarcinoma of a hard palate minor salivary gland: case report and review of the literature.
  • OBJECTIVE: Basal cell adenocarcinoma of a minor salivary gland is extremely rare.
  • The goal of this report is to increase awareness of this rare disease and to review and discuss the differential diagnosis and important considerations in treatment.
  • METHODS: Case report of a basal cell adenocarcinoma of a hard palate minor salivary gland and review of the literature of basal cell adenocarcinoma.
  • RESULTS: Basal cell adenocarcinomas are slow-growing tumours that most commonly involve the parotid gland and very rarely involve minor salivary glands.
  • Histological diagnosis is important to distinguish this tumour from adenoid cystic carcinoma given the significant difference in disease prognosis.
  • CONCLUSIONS: Diagnosis of these tumours must be made histologically.

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Arch Otolaryngol. 1978 Feb;104(2):111-6 [629699.001]
  • [Cites] J Oral Pathol. 1985 Jul;14(6):500-9 [2991488.001]
  • [Cites] Arch Pathol Lab Med. 1988 Feb;112(2):209-11 [2827601.001]
  • [Cites] J Laryngol Otol. 1989 Aug;103(8):756-9 [2769045.001]
  • [Cites] Oral Surg Oral Med Oral Pathol. 1990 Apr;69(4):461-9 [2326038.001]
  • [Cites] Cancer. 1996 Dec 15;78(12):2471-7 [8952553.001]
  • [Cites] Oral Oncol. 2008 Apr;44(4):407-17 [17825603.001]
  • [Cites] HNO. 1998 Sep;46(9):821-5 [9816537.001]
  • [Cites] Int J Oral Maxillofac Surg. 2005 Jul;34(5):528-32 [16053873.001]
  • [Cites] Int J Oral Maxillofac Surg. 2006 Feb;35(2):150-4 [16181771.001]
  • [Cites] Med Oral Patol Oral Cir Bucal. 2006 Mar;11(2):E206-9 [16505803.001]
  • [Cites] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Jan;103(1):77-84 [17178498.001]
  • [Cites] J Oral Pathol Med. 2007 Apr;36(4):207-14 [17391298.001]
  • [Cites] Acta Otolaryngol. 1998 Jul;118(4):588-93 [9726688.001]
  • (PMID = 20030819.001).
  • [ISSN] 1758-3284
  • [Journal-full-title] Head & neck oncology
  • [ISO-abbreviation] Head Neck Oncol
  • [Language] ENG
  • [Grant] United States / NIDCR NIH HHS / DE / K08 DE018061
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2806868
  • [General-notes] NLM/ Original DateCompleted: 20100629
  •  go-up   go-down


36. Visa L, Caballero M, Grau JJ: [Response to metronomic chemotherapy in a metastatic adenoid cystic carcinoma of the parotid gland]. Acta Otorrinolaringol Esp; 2010 Nov-Dec;61(6):452-4
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Response to metronomic chemotherapy in a metastatic adenoid cystic carcinoma of the parotid gland].
  • [Transliterated title] Respuesta a quimioterapia metronómica en un carcinoma adenoide quístico metastásico de parótida.
  • Formerly, salivary gland cancer was considered to be chemoresistant.
  • Data on chemotherapy treatment for adenoid cystic carcinoma consist of phase II trials.
  • Our case report shows for first time the clinical activity of low-dose paclitaxel and cisplatin chemotherapy given separately as a single agent in metastatic adenoid cystic carcinoma of the parotid.
  • [MeSH-major] Antineoplastic Agents / administration & dosage. Carcinoma, Adenoid Cystic / drug therapy. Carcinoma, Adenoid Cystic / secondary. Cisplatin / administration & dosage. Paclitaxel / administration & dosage. Parotid Neoplasms / drug therapy. Parotid Neoplasms / pathology

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • Hazardous Substances Data Bank. CIS-DIAMINEDICHLOROPLATINUM .
  • Hazardous Substances Data Bank. TAXOL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2009 Elsevier España, S.L. All rights reserved.
  • (PMID = 20152955.001).
  • [ISSN] 1988-3013
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Antineoplastic Agents; P88XT4IS4D / Paclitaxel; Q20Q21Q62J / Cisplatin
  •  go-up   go-down


37. Furuse C, Sousa SO, Nunes FD, Magalhães MH, Araújo VC: Myoepithelial cell markers in salivary gland neoplasms. Int J Surg Pathol; 2005 Jan;13(1):57-65
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Myoepithelial cell markers in salivary gland neoplasms.
  • We compared the immunoexpression of 5 myoepithelial cell (MEC) markers (alpha-smooth-muscle actin, calponin, h-caldesmon, vimentin, and S-100-protein) using 16 pleomorphic adenomas (PA), 15 adenoid cystic carcinomas (ACC), and 3 epithelial-myoepithelial carcinomas (EMC) of salivary glands.
  • [MeSH-major] Adenoma, Pleomorphic / metabolism. Biomarkers, Tumor / metabolism. Carcinoma, Adenoid Cystic / metabolism. Myoepithelioma / metabolism. Salivary Gland Neoplasms / metabolism

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15735856.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Biomarkers, Tumor; 0 / Calcium-Binding Proteins; 0 / Microfilament Proteins; 0 / S100 Proteins; 0 / Vimentin; 0 / calponin
  •  go-up   go-down


38. Ito FA, Ito K, Coletta RD, Graner E, de Almeida OP, Lopes MA: Salivary gland tumors: immunohistochemical study of EGF, EGFR, ErbB-2, FAS and Ki-67. Anal Quant Cytol Histol; 2009 Oct;31(5):280-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Salivary gland tumors: immunohistochemical study of EGF, EGFR, ErbB-2, FAS and Ki-67.
  • OBJECTIVE: To analyze the expression of ErbB-1 (Her-1 or EGFR), ErbB-2 (Her-2 or neu), ErbB-3 (Her-3) and ErbB-4 (Her-4) and their correlation in 3 different types of salivary gland tumors.
  • STUDY DESIGN: Immunohistochemical expression of epidermal growth factor (EGF), EGFR, ErbB-2, fatty acid synthase (FAS) and Ki-67 were analyzed in 41 pleomorphic adenoma (PA), in 30 mucoepidermoid carcinoma (MEC) and in 30 adenoid cystic carcinoma (ACC) and correlated with their histologic patterns.
  • CONCLUSION: EGF, EGFR, ErbB-2 and FAS were commonly found and seem to be important in the tumorigenesis of salivary gland tumors, particularly in percentage of strongly positive cases.
  • CONCLUSION: EGF, EGFR, ErbB-2 and FAS were commonly found and seem to be important in the tumorigenesis of salivary gland tumors, particularly in MEC. (Anal Quant Cytol Histol 2009;31:280-287)


39. Driemel O, Maier H, Kraft K, Haase S, Hemmer J: Flow cytometric DNA ploidy in salivary gland tumours. Oncol Rep; 2005 Jan;13(1):161-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Flow cytometric DNA ploidy in salivary gland tumours.
  • This study on 279 tumours of the salivary glands was conducted to analyse whether the assessment of DNA ploidy by flow cytometry may assist histopathology in discriminating benign from malignant types of tumours.
  • The malignant tumours consisted of 18 adenoid cystic adenomas, 10 mucoepidermoid carcinomas, 5 acinic cell carcinomas, 5 carcinoma in pleomorphic adenoma as well as of 12 other malignancies belonging to 7 different tumour entities.
  • Twelve of 50 malignant salivary gland tumours were aneuploid.
  • Examination of consecutive slides actually revealed small assemblies of carcinoma cells that required a final diagnosis as non-invasive carcinoma in pleomorphic adenoma.
  • The most obvious value of DNA flow cytometry in salivary gland tumours is thus its contribution to assist histopathology in identifying potentially malignant lesions.
  • [MeSH-major] DNA, Neoplasm / analysis. Flow Cytometry. Ploidies. Salivary Gland Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Female. Humans. Male. Middle Aged. Salivary Glands / pathology

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15583819.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / DNA, Neoplasm
  •  go-up   go-down


40. Wang XF, Guo Y, Jia SS: [Expression of drug resistance and metastasis related gene in adenoid cystic carcinoma and mucoepidermoid carcinoma]. Zhonghua Kou Qiang Yi Xue Za Zhi; 2007 Feb;42(2):78-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Expression of drug resistance and metastasis related gene in adenoid cystic carcinoma and mucoepidermoid carcinoma].
  • OBJECTIVE: To examine the differential gene expression among adenoid cystic carcinoma ACC-M, low metastasis ACC-2 and low differentiated mucoepidermoid carcinoma MEC-1 with gene array, and detect three important genes with real-time quantitative PCR.
  • [MeSH-major] Carcinoma, Adenoid Cystic / genetics. Carcinoma, Mucoepidermoid / genetics. Drug Resistance, Neoplasm / genetics. Genes, MDR. Neoplasm Metastasis / genetics. Salivary Gland Neoplasms / genetics

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • Genetic Alliance. consumer health - Mucoepidermoid carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17462150.001).
  • [ISSN] 1002-0098
  • [Journal-full-title] Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
  • [ISO-abbreviation] Zhonghua Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  •  go-up   go-down


41. Li LJ, Li Y, Wen YM, Liu H, Zhao HW: Clinical analysis of salivary gland tumor cases in West China in past 50 years. Oral Oncol; 2008 Feb;44(2):187-92
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical analysis of salivary gland tumor cases in West China in past 50 years.
  • In our study, 3461 cases of salivary gland tumor treated between 1955 and 2002 at West China Stomatology Hospital of Sichuan University were retrospectively analyzed, and compared with the previous reports.
  • The findings are as follows: the average ages of salivary gland tumor patients were 41.38 years for the benign cases and 45.20 for the malignant ones; the male:female ratio was 0.
  • 99:1 in the benign cases and 1.34:1 in the malignant ones; primary tumors were mostly in the parotid gland, palate and submandibular gland in sequence.
  • Pleomorphic adenoma was the most frequent benign tumor followed by Warthin's tumor and basal cell adenoma, whereas mucoepidermoid carcinoma, adenoid cystic carcinoma and adenocarcinoma not otherwise specified were the most frequent malignant tumors.
  • The incidence of salivary gland tumors increased with age.
  • The parotid gland and palate were the most common locations of salivary gland tumors.
  • Pleomorphic adenoma and mucoepidermoid carcinoma were the most frequent benign and malignant tumors, respectively.
  • [MeSH-major] Adenoma, Pleomorphic / epidemiology. Carcinoma, Mucoepidermoid / epidemiology. Salivary Gland Neoplasms / epidemiology
  • [MeSH-minor] Adenocarcinoma / pathology. Adenolymphoma / pathology. Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Adenoid Cystic / pathology. Child. Child, Preschool. China / epidemiology. Female. Humans. Incidence. Infant. Male. Middle Aged. Palatal Neoplasms / pathology. Parotid Neoplasms / pathology. Retrospective Studies

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [ErratumIn] Oral Oncol. 2011 Sep;47(9):929-30
  • (PMID = 17418612.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  •  go-up   go-down


42. Maiorano E, Favia G, Pece S, Resta L, Maisonneuve P, Di Fiore PP, Capodiferro S, Urbani U, Viale G: Prognostic implications of NUMB immunoreactivity in salivary gland carcinomas. Int J Immunopathol Pharmacol; 2007 Oct-Dec;20(4):779-89
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Prognostic implications of NUMB immunoreactivity in salivary gland carcinomas.
  • We set out to explore the immunohistochemical expression of Numb in normal and neoplastic (28 adenoid cystic and 34 mucoepidermoid carcinomas) salivary glands, and correlated the results with the clinico-pathologic features of the neoplasms.
  • In salivary carcinomas, we detected diffuse and intense Numb immunostaining in 5 adenoid cystic and 8 mucoepidermoid carcinomas.
  • By contrast, the majority of adenoid cystic and mucoepidermoid cancers showed only moderate (14 and 5 cases) or focal staining (9 and 21 cases), respectively.
  • The corresponding expression of Numb mRNA was documented in normal parotid gland and adenoid cystic carcinoma.
  • Numb immunoreactivity was inversely correlated with the histological grade and Ki-67 immunoreactivity of both adenoid cystic and mucoepidermoid carcinomas.
  • These data suggest that loss of Numb is implicated in aberrant differentiation programs of salivary gland carcinomas and may serve as a prognostic indicator in patients treated for these neoplasms.
  • [MeSH-major] Carcinoma, Adenoid Cystic / genetics. Carcinoma, Mucoepidermoid / genetics. Membrane Proteins / genetics. Nerve Tissue Proteins / genetics. Salivary Gland Neoplasms / genetics
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biomarkers, Tumor. DNA, Neoplasm / biosynthesis. DNA, Neoplasm / genetics. Female. Humans. Immunohistochemistry. Ki-67 Antigen / genetics. Male. Middle Aged. Parotid Gland / metabolism. Prognosis. Proportional Hazards Models. RNA, Neoplasm / biosynthesis. RNA, Neoplasm / genetics. Reverse Transcriptase Polymerase Chain Reaction. Submandibular Gland / metabolism. Survival Analysis

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18179751.001).
  • [ISSN] 0394-6320
  • [Journal-full-title] International journal of immunopathology and pharmacology
  • [ISO-abbreviation] Int J Immunopathol Pharmacol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Neoplasm; 0 / Ki-67 Antigen; 0 / Membrane Proteins; 0 / Nerve Tissue Proteins; 0 / Numb protein, human; 0 / RNA, Neoplasm
  •  go-up   go-down


43. Pfeffer MR, Talmi Y, Catane R, Symon Z, Yosepovitch A, Levitt M: A phase II study of Imatinib for advanced adenoid cystic carcinoma of head and neck salivary glands. Oral Oncol; 2007 Jan;43(1):33-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A phase II study of Imatinib for advanced adenoid cystic carcinoma of head and neck salivary glands.
  • Adenoid cystic carcinoma of the salivary glands is characterized by a poor response to chemotherapy.
  • Most cases of adenoid cystic carcinoma express the c-kit protein.
  • We therefore hypothesized that Imatinib may be an effective drug in patients with locally advanced or metastatic adenoid cystic carcinoma and conducted a phase 2 trial in order to study this.
  • Patients with locally advanced or metastatic adenoid cystic carcinoma and c-kit positive tumours were eligible.
  • Imatinib has no major effect on advanced adenoid cystic carcinoma of the head and neck.
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Carcinoma, Adenoid Cystic / drug therapy. Piperazines / therapeutic use. Pyrimidines / therapeutic use. Salivary Gland Neoplasms / drug therapy

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Cancer Chemotherapy.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • Hazardous Substances Data Bank. IMATINIB MESYLATE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16757202.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase II; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Benzamides; 0 / Piperazines; 0 / Pyrimidines; 8A1O1M485B / Imatinib Mesylate
  •  go-up   go-down


44. Chen AM, Granchi PJ, Garcia J, Bucci MK, Fu KK, Eisele DW: Local-regional recurrence after surgery without postoperative irradiation for carcinomas of the major salivary glands: implications for adjuvant therapy. Int J Radiat Oncol Biol Phys; 2007 Mar 15;67(4):982-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Local-regional recurrence after surgery without postoperative irradiation for carcinomas of the major salivary glands: implications for adjuvant therapy.
  • PURPOSE: To determine factors predictive of local-regional recurrence (LRR) after surgery alone for carcinomas of the major salivary glands in an attempt to evaluate the potential role of postoperative radiation therapy.
  • METHODS AND MATERIALS: Between 1960 and 2004, 207 patients with carcinomas of the major salivary glands were treated with definitive surgery without postoperative radiation therapy.
  • Histology was: 67 mucoepidermoid (32%), 50 adenoid cystic (24%), 34 acinic cell (16%), 23 malignant mixed (11%), 16 adenocarcinoma (8%), 6 oncocytic (3%), 6 myoepithelial (3%), and 5 other (2%).
  • CONCLUSION: Lymph node metastasis, high tumor grade, positive margins, and T3-4 stage predict for significant rates of LRR after surgery for carcinomas of the major salivary glands.
  • [MeSH-major] Carcinoma / secondary. Carcinoma / surgery. Neoplasm Recurrence, Local. Salivary Gland Neoplasms / pathology. Salivary Gland Neoplasms / surgery

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • COS Scholar Universe. author profiles.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17241753.001).
  • [ISSN] 0360-3016
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


45. Batzakakis D, Apostolopoulos K, Bardanis I: A case report of coexistence of a sialolith and an adenoid cystic carcinoma in the submandibular gland. Med Oral Patol Oral Cir Bucal; 2006 May;11(3):E286-8
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case report of coexistence of a sialolith and an adenoid cystic carcinoma in the submandibular gland.
  • The occurrence of sialoliths in the submandibular gland is 80% due to the specific anatomy of both the gland and its duct.
  • The diagnosis is rather easy because of the obvious clinical signs of the entity.
  • The stones do not tend to occur within the gland as frequently as in the respective duct.
  • In addition to the sialolith the pathological examination revealed the existence of an adenoid cystic carcinoma (ACC), that extended to the neighboring skeletal muscle.
  • This is the reason why we believe it would be useful to report this case of a large stone (14 mm in diameter) located in the submandibular gland coexisting with ACC.
  • [MeSH-major] Carcinoma, Adenoid Cystic / complications. Salivary Gland Calculi / complications. Submandibular Gland Neoplasms / complications

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16648756.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
  •  go-up   go-down


46. Seethala RR, Pasha TL, Raghunath PN, Livolsi VA, Zhang PJ: The selective expression of CD43 in adenoid cystic carcinoma. Appl Immunohistochem Mol Morphol; 2008 Mar;16(2):165-72
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The selective expression of CD43 in adenoid cystic carcinoma.
  • We describe CD43 expression by immunohistochemistry and mRNA in situ hybridization in adenoid cystic carcinomas (ACCs).
  • CD43 immunoreactivity with 2 different antibodies was detected mainly in ACC but also 1 membranous type basal cell adenocarcinoma and 1 colonic adenocarcinoma.
  • Nine of 20 (45%) ACC (8/17 salivary/mucoserous and 1/3 mammary) showed immunoreactivity with clone MT1 whereas 4 (23.5%) salivary ACC also showed immunoreactivity with clone DF-T1.
  • Hence, CD43 seems to be selectively expressed in a subset of ACC and its significance in salivary tumors is discussed.

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • COS Scholar Universe. author profiles.
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18227725.001).
  • [ISSN] 1541-2016
  • [Journal-full-title] Applied immunohistochemistry & molecular morphology : AIMM
  • [ISO-abbreviation] Appl. Immunohistochem. Mol. Morphol.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD43; 0 / RNA, Messenger; 0 / UN1 sialoglycoprotein, human
  •  go-up   go-down


47. Brackrock S, Krüll A, Röser K, Schwarz R, Riethdorf L, Alberti W: Neutron therapy, prognostic factors and dedifferentiation of adenoid cystic carcinomas (ACC) of salivary glands. Anticancer Res; 2005 Mar-Apr;25(2B):1321-6
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neutron therapy, prognostic factors and dedifferentiation of adenoid cystic carcinomas (ACC) of salivary glands.
  • PURPOSE: Analysis of the efficacy of fast neutron radiotherapy in the treatment of adenoid cystic carcinomas (ACC) of the salivary glands, identification of prognostic variables and dedifferentiation after radiotherapy.
  • PATIENTS AND METHODS: Histological slides of primary and recurrent lesions of 71 patients were reviewed to confirm the diagnosis and to analyse subtypes.
  • [MeSH-major] Carcinoma, Adenoid Cystic / radiotherapy. Fast Neutrons / therapeutic use. Salivary Gland Neoplasms / radiotherapy

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15865085.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  •  go-up   go-down


48. Ben-Izhak O, Laster Z, Araidy S, Nagler RM: TUNEL - an efficient prognosis predictor of salivary malignancies. Br J Cancer; 2007 Apr 10;96(7):1101-6
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] TUNEL - an efficient prognosis predictor of salivary malignancies.
  • Biological markers are necessary for predicting prognosis of salivary malignancies and better understanding the pathogenesis of salivary cancer.
  • We analysed terminal deoxynucleotidyl transferase (TdT)-mediated biotinylated deoxyuridine-triphosphate (dUTP)-biotin nick-end labelling (TUNEL), p53 and Ki67 expression in 66 patients with malignant salivary tumours by immonohistochemistry, and correlated the data with survival, disease-free survival, tumour grade, stage, and local and distant metastasis.
  • TUNEL efficiently predicted poor prognosis in salivary malignancies.
  • The correlation between TUNEL, p53 and Ki67 staining and survival probabilities, and the pathological grade, stage and metastasis spread of salivary malignancies makes this a highly effective tool in patient follow-up and prognosis.
  • [MeSH-major] Apoptosis. In Situ Nick-End Labeling. Salivary Gland Neoplasms / pathology
  • [MeSH-minor] Adenocarcinoma / metabolism. Adenocarcinoma / pathology. Adolescent. Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / metabolism. Carcinoma, Adenoid Cystic / metabolism. Carcinoma, Adenoid Cystic / pathology. Carcinoma, Mucoepidermoid / metabolism. Carcinoma, Mucoepidermoid / pathology. Carcinoma, Squamous Cell / metabolism. Carcinoma, Squamous Cell / pathology. Female. Humans. Ki-67 Antigen / metabolism. Male. Middle Aged. Predictive Value of Tests. Prognosis. Survival Rate. Tumor Suppressor Protein p53 / metabolism

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Pathol Annu. 1987;22 Pt 1:1-53 [3033585.001]
  • [Cites] Laryngoscope. 1986 Oct;96(10):1139-44 [3762288.001]
  • [Cites] Mol Cell Biol. 1988 Feb;8(2):531-9 [2832726.001]
  • [Cites] J Laryngol Otol. 1989 Oct;103(10):939-44 [2685148.001]
  • [Cites] Oncology (Williston Park). 1989 Feb;3(2):47-56; discussion 56, 58, 62 [2701410.001]
  • [Cites] Oncology (Williston Park). 1989 Mar;3(3):85-91; discussion 94, 99 [2701414.001]
  • [Cites] Curr Opin Oncol. 1990 Jun;2(3):589-95 [2092779.001]
  • [Cites] Hepatology. 1995 May;21(5):1465-8 [7737654.001]
  • [Cites] Methods Cell Biol. 1995;46:29-39 [7541886.001]
  • [Cites] EMBO J. 1996 Jul 15;15(14):3693-701 [8758936.001]
  • [Cites] Cancer. 1998 Feb 1;82(3):439-47 [9452259.001]
  • [Cites] Histopathology. 1998 Jan;32(1):28-34 [9522213.001]
  • [Cites] Histopathology. 1998 Sep;33(3):240-7 [9777390.001]
  • [Cites] Cancer. 1999 Mar 1;85(5):1018-25 [10091783.001]
  • [Cites] Oncology. 1999 Apr;56(3):239-47 [10202280.001]
  • [Cites] Histopathology. 1999 Mar;34(3):241-9 [10217565.001]
  • [Cites] Adv Anat Pathol. 1999 May;6(3):140-8 [10342011.001]
  • [Cites] Br J Cancer. 1999 Jul;80 Suppl 1:34-7 [10466759.001]
  • [Cites] Hum Pathol. 1999 Sep;30(9):1097-105 [10492046.001]
  • [Cites] Cancer. 1999 Sep 15;86(6):913-20 [10491515.001]
  • [Cites] Oral Dis. 1999 Apr;5(2):117-22 [10522207.001]
  • [Cites] Magy Onkol. 2004;48(4):309-13 [15655576.001]
  • [Cites] Histopathology. 2006 May;48(6):674-82 [16681683.001]
  • [Cites] Pathol Res Pract. 2000;196(3):167-74 [10729921.001]
  • [Cites] Anticancer Res. 2000 Mar-Apr;20(2B):1213-9 [10810424.001]
  • [Cites] Appl Immunohistochem Mol Morphol. 2000 Sep;8(3):175-82 [10981868.001]
  • [Cites] Ann Urol (Paris). 2000 Aug;34(4):236-9 [10994142.001]
  • [Cites] Histopathology. 2001 Nov;39(5):469-75 [11737304.001]
  • [Cites] J Exp Clin Cancer Res. 2002 Sep;21(3):371-5 [12385580.001]
  • [Cites] Histopathology. 2002 Dec;41(6):519-25 [12460204.001]
  • [Cites] J Pathol. 2003 Jan;199(1):90-7 [12474231.001]
  • [Cites] Oncology. 2003;64(4):389-98 [12759537.001]
  • [Cites] J Urol. 2003 Jul;170(1):241-5 [12796697.001]
  • [Cites] Cancer. 1971 Jun;27(6):1415-8 [4325986.001]
  • [Cites] Oral Surg Oral Med Oral Pathol. 1980 Mar;49(3):229-32 [6928307.001]
  • [Cites] J Pathol. 1985 May;146(1):51-8 [4009321.001]
  • [Cites] Head Neck Surg. 1986 Nov-Dec;9(2):82-92 [3623942.001]
  • (PMID = 17325701.001).
  • [ISSN] 0007-0920
  • [Journal-full-title] British journal of cancer
  • [ISO-abbreviation] Br. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 0 / Tumor Suppressor Protein p53
  • [Other-IDs] NLM/ PMC2360125
  •  go-up   go-down


49. Daneshbod Y, Negahban S, Khademi B, Daneshbod K: Epithelial myoepithelial carcinoma of the parotid gland with malignant ductal and myoepithelial components arising in a pleomorphic adenoma: a case report with cytologic, histologic and immunohistochemical correlation. Acta Cytol; 2007 Sep-Oct;51(5):807-13
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epithelial myoepithelial carcinoma of the parotid gland with malignant ductal and myoepithelial components arising in a pleomorphic adenoma: a case report with cytologic, histologic and immunohistochemical correlation.
  • BACKGROUND: To describe the cytologic, histologic and immunohistochemical findings of a case of epithelial myoepithelial carcinoma (EMC) arising from a pleomorphic adenoma (PA) of the parotid with both malignant epithelial and myoepithelial components.
  • The cytology was reported as salivary gland neoplasm, "suggestive of adenoid cystic carcinoma, less likely pleomorphic adenoma."
  • The final diagnosis was EMC ex PA.
  • CONCLUSION: Although previous reports mention the difficulties in diagnosing EMC and differentiation from the more common salivary gland neoplasms such as PA, we like to emphasize the cytologic confusion that results when the tumors coexist.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Carcinoma / pathology. Myoepithelioma / pathology. Neoplasms, Second Primary / pathology. Parotid Neoplasms / pathology


50. Buchner A, Merrell PW, Carpenter WM: Relative frequency of intra-oral minor salivary gland tumors: a study of 380 cases from northern California and comparison to reports from other parts of the world. J Oral Pathol Med; 2007 Apr;36(4):207-14
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Relative frequency of intra-oral minor salivary gland tumors: a study of 380 cases from northern California and comparison to reports from other parts of the world.
  • BACKGROUND: The relative frequency of individual intra-oral minor salivary gland tumors (IMSGT) is not well documented in the literature.
  • Tumors were classified according to the 2005 WHO classification of salivary gland tumors.
  • Of the malignant tumors, mucoepidermoid carcinoma was the most common (21.8%), followed by polymorphous low-grade adenocarcinoma (7.1%), adenoid cystic carcinoma (6.3%), adenocarcinoma, not otherwise specified (NOS; 2.1%), acinic cell carcinoma (1.6%), clear cell carcinoma, NOS (1.0%), and carcinoma ex PA (0.5%).
  • To determine the true relative frequency, more studies should be conducted, on a large number of cases from one source, by experienced pathologists in the field of salivary gland tumors.
  • [MeSH-major] Salivary Gland Neoplasms / epidemiology. Salivary Glands, Minor / pathology
  • [MeSH-minor] Adenoma, Pleomorphic / epidemiology. Adenoma, Pleomorphic / pathology. Adolescent. Adult. Aged. Aged, 80 and over. California / epidemiology. Carcinoma, Adenoid Cystic / epidemiology. Carcinoma, Adenoid Cystic / pathology. Carcinoma, Mucoepidermoid / epidemiology. Carcinoma, Mucoepidermoid / pathology. Child. Cystadenoma / epidemiology. Cystadenoma / pathology. Female. Humans. Male. Middle Aged. Prevalence

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17391298.001).
  • [ISSN] 0904-2512
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  •  go-up   go-down


51. Zhang Y, Liu J, Xue F, Li J: p16 tumor suppressor therapy in salivary adenoid cystic carcinoma cell line SACC83. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2005 Jul;100(1):70-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] p16 tumor suppressor therapy in salivary adenoid cystic carcinoma cell line SACC83.
  • OBJECTIVE: This study aimed to determine the growth inhibitory effects of transfecting the wild-type p16 gene into human salivary adenoid cystic carcinoma (SACC) cells in vitro.
  • CONCLUSION: The study confirmed the reversal effect of wild-type p16 on malignant phenotype of the salivary adenoid cystic carcinoma and provides valuable data for further clinical trial of gene therapy with p16.
  • [MeSH-major] Carcinoma, Adenoid Cystic / therapy. Genes, p16 / physiology. Genetic Therapy. Salivary Gland Neoplasms / therapy

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Genes and Gene Therapy.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • Hazardous Substances Data Bank. METHYLTHIAZOLETETRAZOLIUM .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15953919.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Coloring Agents; 0 / Tetrazolium Salts; 0 / Thiazoles; 298-93-1 / thiazolyl blue; 9007-49-2 / DNA
  •  go-up   go-down


52. Zhang CY, Zhou XJ, Zhang ZY, Li J: [DNA methylation in salivary adenoid cystic carcinoma cell lines]. Zhonghua Kou Qiang Yi Xue Za Zhi; 2007 Mar;42(3):135-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [DNA methylation in salivary adenoid cystic carcinoma cell lines].
  • OBJECTIVE: To investigate the promoter methylation status of tumor suppressor gene and the relationship between promoter methylation and mRNA, protein expression of tumor suppressor gene in salivary adenoid cystic carcinoma (ACC) cell lines.
  • RESULTS: All the three salivary ACC cell lines exhibited E-cad, p16 promoter methylation, but no methylation of RASSF1A, DAPK, and MGMT was found.
  • [MeSH-major] Carcinoma, Adenoid Cystic / genetics. DNA Methylation. Salivary Gland Neoplasms / genetics

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17565817.001).
  • [ISSN] 1002-0098
  • [Journal-full-title] Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
  • [ISO-abbreviation] Zhonghua Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Cadherins; 0 / Neoplasm Proteins; 0 / P16 protein, human
  •  go-up   go-down


53. Ye JH, Gao J, Wu YN, Hu YJ, Zhang CP, Xu TL: Identification of acid-sensing ion channels in adenoid cystic carcinomas. Biochem Biophys Res Commun; 2007 Apr 20;355(4):986-92
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Identification of acid-sensing ion channels in adenoid cystic carcinomas.
  • The response of adenoid cystic carcinoma (ACC) cells to acidic solution was studied using whole-cell patch-clamp recording in the current study.
  • An inward, amiloride-sensitive Na(+) current was identified in cultured ACC-2 cells while not in normal human salivary gland epithelial cells.
  • [MeSH-major] Carcinoma, Adenoid Cystic / metabolism. Membrane Proteins / metabolism. Nerve Tissue Proteins / metabolism. Sodium Channels / metabolism
  • [MeSH-minor] Acid Sensing Ion Channels. Cell Line, Tumor. Electrophysiology. Gene Expression Regulation. Humans. Patch-Clamp Techniques. Protons. Salivary Glands / metabolism. Zinc / metabolism

  • Hazardous Substances Data Bank. ZINC, ELEMENTAL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17324378.001).
  • [ISSN] 0006-291X
  • [Journal-full-title] Biochemical and biophysical research communications
  • [ISO-abbreviation] Biochem. Biophys. Res. Commun.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Acid Sensing Ion Channels; 0 / Membrane Proteins; 0 / Nerve Tissue Proteins; 0 / Protons; 0 / Sodium Channels; J41CSQ7QDS / Zinc
  •  go-up   go-down


54. Akrish S, Peled M, Ben-Izhak O, Nagler RM: Malignant salivary gland tumors and cyclo-oxygenase-2: a histopathological and immunohistochemical analysis with implications on histogenesis. Oral Oncol; 2009 Dec;45(12):1044-50
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant salivary gland tumors and cyclo-oxygenase-2: a histopathological and immunohistochemical analysis with implications on histogenesis.
  • The classification system for malignant salivary gland tumors (MST) is largely dependent on its histogenesis.
  • Fifty six primary major and minor gland MST were stained with anti-cox-2 antibody and rated with a combined score that added a scale of intensity to the percentage of tumor cells that overexpressed the cox-2 protein.
  • Strong cox-2 overexpression was noted in all MST of proposed excretory duct origin: salivary duct carcinoma (100%), mucoepidermoid carcinoma (MEC) (92%), and adenocarcinoma nos (AdC nos) (83%).
  • Primary squamous cell carcinoma (PSCC) was the exception.
  • Negative expression was noted in all tumors of proposed intercalated duct origin (adenoid cystic carcinoma, basal cell adenocarcinoma and acinic cell carcinoma) with the exception of one case of polymorphous low grade adenocarcinoma.
  • Strong cox-2 overexpression was noted in the epidermoid cells of MEC, abluminal duct cells surrounding the duct-like structures and ductal cells of AdC nos and salivary duct carcinoma.
  • [MeSH-major] Biomarkers, Tumor / analysis. Cyclooxygenase 2 / analysis. Salivary Gland Neoplasms / enzymology. Salivary Gland Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19729335.001).
  • [ISSN] 1879-0593
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 1.14.99.1 / Cyclooxygenase 2
  •  go-up   go-down


55. do Nascimento KC, de Faria PR, Dib LL, Ferreira de Aguiar MC, Cardoso SV, Chen J, Loyola AM: Immunohistochemical localization of the NM23 protein in salivary gland neoplasms with distinct biological behavior. Virchows Arch; 2006 Dec;449(6):660-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Immunohistochemical localization of the NM23 protein in salivary gland neoplasms with distinct biological behavior.
  • However, its association with the metastatic phenotype of salivary gland neoplasms (SGN) remains unknown.
  • To evaluate the role of NM23 in SGN, the expression patterns of NM23 in the following were compared: benign (pleomorphic adenoma) vs malignant (adenoid cystic carcinoma and mucoepidermoid carcinoma) SGN, and primary malignancies with/without evidence of metastasis vs their metastatic implants (MI).
  • [MeSH-major] Nucleoside-Diphosphate Kinase / analysis. Salivary Gland Neoplasms / chemistry

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Clin Pathol. 2004 Dec;57(12):1312-8 [15563674.001]
  • [Cites] Lab Invest. 1996 Jan;74(1):158-67 [8569178.001]
  • [Cites] Cancer Res. 2000 Jan 15;60(2):298-304 [10667580.001]
  • [Cites] Int J Cancer. 1997 Aug 22;74(4):416-20 [9291431.001]
  • [Cites] Cancer Res. 1989 Sep 15;49(18):5185-90 [2475243.001]
  • [Cites] J Bioenerg Biomembr. 2003 Feb;35(1):73-9 [12848344.001]
  • [Cites] Oral Oncol. 2001 Apr;37(3):315-22 [11287288.001]
  • [Cites] Pathology. 1999 May;31(2):123-6 [10399167.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 1997 Apr;123(4):412-9 [9109790.001]
  • [Cites] Hua Xi Yi Ke Da Xue Xue Bao. 1995 Dec;26(4):367-70 [8732053.001]
  • [Cites] Jpn J Cancer Res. 2001 Mar;92(3):361-6 [11267948.001]
  • [Cites] Cell Growth Differ. 1992 Dec;3(12):873-9 [1472467.001]
  • [Cites] Cell. 2003 Mar 7;112(5):659-72 [12628186.001]
  • [Cites] Zhonghua Kou Qiang Yi Xue Za Zhi. 1997 Jan;32(1):4-6 [10677933.001]
  • [Cites] ORL J Otorhinolaryngol Relat Spec. 2001 Jul-Aug;63(4):233-42 [11408820.001]
  • [Cites] J Natl Cancer Inst. 1988 Apr 6;80(3):200-4 [3346912.001]
  • [Cites] Cell Tissue Res. 2005 Dec;322(3):365-78 [16082520.001]
  • [Cites] Bioessays. 1995 Jan;17(1):53-62 [7702594.001]
  • [Cites] Cancer Res. 1998 Jul 1;58(13):2766-71 [9661889.001]
  • [Cites] Zhonghua Kou Qiang Yi Xue Za Zhi. 1997 Nov;32(6):341-3 [11189305.001]
  • [Cites] J Biol Chem. 1999 Aug 6;274(32):22821-9 [10428867.001]
  • [Cites] J Pathol. 1994 Jan;172(1):27-34 [7931824.001]
  • [Cites] Am J Pathol. 1994 Jul;145(1):26-32 [8030752.001]
  • [Cites] J Bioenerg Biomembr. 2000 Jun;32(3):301-8 [11768314.001]
  • [Cites] Zhonghua Bing Li Xue Za Zhi. 2001 Aug;30(4):273-5 [11758216.001]
  • [Cites] Exp Cell Res. 2004 Aug 1;298(1):275-84 [15242782.001]
  • [Cites] Hua Xi Kou Qiang Yi Xue Za Zhi. 2004 Apr;22(2):155-7 [15190803.001]
  • [Cites] Oncology. 1997 Jan-Feb;54(1):63-8 [8978595.001]
  • (PMID = 17091257.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / NM23 Nucleoside Diphosphate Kinases; EC 2.7.4.6 / NME1 protein, human; EC 2.7.4.6 / Nucleoside-Diphosphate Kinase
  •  go-up   go-down


56. Yan BZ, Wang J, Zhang B, Dong FS, Hou L, Wang X: [Expression of p53 gene with DNA polbeta and CMV promoter in salivary adenoid cystic carcinoma cells]. Hua Xi Kou Qiang Yi Xue Za Zhi; 2007 Feb;25(1):22-5, 28
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Expression of p53 gene with DNA polbeta and CMV promoter in salivary adenoid cystic carcinoma cells].
  • OBJECTIVE: To evaluate the activity of DNA polbeta promoter on p53 gene in salivary adenoid cystic carcinoma (SACC) cells.
  • [MeSH-major] Carcinoma, Adenoid Cystic. Salivary Gland Neoplasms

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • Hazardous Substances Data Bank. HYDROGEN PEROXIDE .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17375570.001).
  • [ISSN] 1000-1182
  • [Journal-full-title] Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology
  • [ISO-abbreviation] Hua Xi Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / RNA, Messenger; 9007-49-2 / DNA; BBX060AN9V / Hydrogen Peroxide
  •  go-up   go-down


57. Lu YG, Ding LC, Zhou HY, Deng SS, Wang QM, Xiong RH, Yang HJ: [The expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in transplanted tumor of salivary adenoid cystic carcinoma cell lines]. Shanghai Kou Qiang Yi Xue; 2006 Oct;15(5):526-30
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in transplanted tumor of salivary adenoid cystic carcinoma cell lines].
  • CONCLUSION: The differential expression pattern of MMP-2, MMP-7, MMP-9, and TIMP-1 in 2 tumor models may result in different metastasis potential; The 2 tumor models provide good study model for investigation of the metastatic mechanism of salivary adenoid cystic carcinoma.
  • [MeSH-major] Carcinoma, Adenoid Cystic. Cell Line, Tumor. Disease Models, Animal. Matrix Metalloproteinases / biosynthesis. Neoplasm Transplantation. Salivary Gland Neoplasms. Tissue Inhibitor of Metalloproteinases / biosynthesis

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17348230.001).
  • [ISSN] 1006-7248
  • [Journal-full-title] Shanghai kou qiang yi xue = Shanghai journal of stomatology
  • [ISO-abbreviation] Shanghai Kou Qiang Yi Xue
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / RNA, Messenger; 0 / Tissue Inhibitor of Metalloproteinase-1; 0 / Tissue Inhibitor of Metalloproteinases; 127497-59-0 / Tissue Inhibitor of Metalloproteinase-2; EC 3.4.24.- / Matrix Metalloproteinases; EC 3.4.24.23 / Matrix Metalloproteinase 7; EC 3.4.24.24 / Matrix Metalloproteinase 2; EC 3.4.24.35 / Matrix Metalloproteinase 9
  •  go-up   go-down


58. Bhatia KS, Rasalkar DD, Lee YP, Wong KT, King AD, Yuen HY, Ahuja AT: Evaluation of real-time qualitative sonoelastography of focal lesions in the parotid and submandibular glands: applications and limitations. Eur Radiol; 2010 Aug;20(8):1958-64
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To evaluate qualitative ultrasound elastography for focal salivary gland masses identified during routine clinical practice.
  • METHODS: Sixty-five parotid or submandibular masses in 61 patients underwent real-time qualitative ultrasound elastography and were scored on colour-scaled elastograms in terms of their stiffness relative to adjacent normal salivary parenchyma from ES 1 (soft) to ES 4 (stiff).
  • This was correlated with diagnosis from aspiration cytology or histology.
  • RESULTS: There were 29 Warthin's tumours (WTs), 23 pleomorphic adenomas (PAs), 2 adenoid cystic carcinomas, 1 adenosquamous carcinoma, 1 nodal metastasis from nasopharyngeal carcinoma, 1 lymphoma (2 deposits), 3 Kuttner tumours and 4 cases of Kimura's disease.
  • All three primary salivary malignancies were ES 4 compared with 1/29 WTs and 16/23 PAs.
  • CONCLUSION: These preliminary findings suggest that qualitative real-time ultrasound elastography, although an ancillary technique to conventional ultrasound in the salivary glands, is likely to have a poor ability to discriminate benign lesions (particularly PAs) from malignant disease.
  • [MeSH-major] Elasticity Imaging Techniques / methods. Parotid Gland / diagnostic imaging. Parotid Neoplasms / diagnostic imaging. Submandibular Gland / diagnostic imaging. Submandibular Gland Neoplasms / diagnostic imaging

  • COS Scholar Universe. author profiles.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Radiology. 2007 Apr;243(1):258-67 [17293571.001]
  • [Cites] J Ultrasound Med. 2007 Jun;26(6):807-15 [17526612.001]
  • [Cites] Clin Radiol. 1995 Mar;50(3):170-3 [7889708.001]
  • [Cites] AJR Am J Roentgenol. 2008 Aug;191(2):604-10 [18647939.001]
  • [Cites] Eur Radiol. 2003 May;13(5):964-75 [12695816.001]
  • [Cites] J Clin Endocrinol Metab. 2007 Aug;92 (8):2917-22 [17535993.001]
  • [Cites] Radiology. 2005 Oct;237(1):202-11 [16118150.001]
  • [Cites] Pathol Annu. 1992;27 Pt 2:213-45 [1316597.001]
  • [Cites] Otolaryngol Head Neck Surg. 2007 Oct;137(4):642-6 [17903584.001]
  • [Cites] J Oral Pathol Med. 1994 Jul;23(6):256-61 [7932245.001]
  • [Cites] Radiology. 2005 Dec;237(3):981-5 [16251396.001]
  • [Cites] Ultrasound Med Biol. 2003 Jul;29(7):913-9 [12878235.001]
  • [Cites] Diagn Cytopathol. 2000 Mar;22(3):139-46 [10679992.001]
  • [Cites] Thyroid. 2008 May;18(5):523-31 [18466077.001]
  • [Cites] Acad Radiol. 2007 Feb;14 (2):193-200 [17236992.001]
  • [Cites] Radiology. 2008 Aug;248(2):662-9 [18539888.001]
  • [Cites] Gastrointest Endosc. 2007 Jun;65(7):971-8 [17531630.001]
  • [Cites] Diagn Cytopathol. 1997 Aug;17(2):92-8 [9258615.001]
  • [Cites] Eur Radiol. 2002 Mar;12 (3):600-4 [11870475.001]
  • [Cites] Cytopathology. 2002 Apr;13(2):121-7 [11952751.001]
  • [Cites] Ultraschall Med. 2006 Dec;27(6):535-42 [17160759.001]
  • [Cites] J Ultrasound Med. 2009 Jul;28(7):861-7 [19546328.001]
  • [Cites] Laryngoscope. 1991 Mar;101(3):245-9 [2000011.001]
  • [Cites] Radiology. 2006 May;239(2):341-50 [16484352.001]
  • [Cites] Ultrasound Q. 2007 Dec;23 (4):255-68 [18090836.001]
  • (PMID = 20407904.001).
  • [ISSN] 1432-1084
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


59. Sequeiros-Santiago G, García-Carracedo D, Fresno MF, Suarez C, Rodrigo JP, Gonzalez MV: Oncogene amplification pattern in adenoid cystic carcinoma of the salivary glands. Oncol Rep; 2009 May;21(5):1215-22
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Oncogene amplification pattern in adenoid cystic carcinoma of the salivary glands.
  • [MeSH-major] Carcinoma, Adenoid Cystic / genetics. Gene Amplification. Oncogenes. Salivary Gland Neoplasms / genetics


60. Tetsu O, Phuchareon J, Chou A, Cox DP, Eisele DW, Jordan RC: Mutations in the c-Kit gene disrupt mitogen-activated protein kinase signaling during tumor development in adenoid cystic carcinoma of the salivary glands. Neoplasia; 2010 Sep;12(9):708-17
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mutations in the c-Kit gene disrupt mitogen-activated protein kinase signaling during tumor development in adenoid cystic carcinoma of the salivary glands.
  • This study reports an opposite finding: we have found strong evidence that the MAPK pathway is inhibited in a subset of adenoid cystic carcinomas (ACCs) of the salivary glands.
  • We performed mutational analysis of the c-Kit gene (KIT in 17 cases of ACC and found that 2 cases of ACC had distinct missense mutations in KIT at both the genomic DNA and messenger RNA levels.
  • We performed further mutational analysis of the downstream effectors in the c-Kit pathway in the genes HRAS, KRAS, NRAS, BRAF, PIK3CA, and PTEN.
  • Because ACC seems to proliferate despite inactivation of the c-Kit signaling pathway, we suggest that selective inhibition of c-Kit is probably not a suitable treatment strategy for ACC.


61. Qi ZZ, Shang DH, Qu CF, Sun CF: [The expression of M-phase promoting factor in salivary adenoid cystic carcinoma]. Shanghai Kou Qiang Yi Xue; 2007 Jun;16(3):243-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The expression of M-phase promoting factor in salivary adenoid cystic carcinoma].
  • PURPOSE: To study the expression and clinical significance of M-phase promoting factor (MPF) in salivary adenoid cystic carcinoma (SACC).
  • METHODS: The expression of MPF was investigated in 40 salivary adenoid cystic carcinomas and 40 normal salivary tissues by immunohistochemistry.
  • RESULTS: The expression of MPF was significantly higher in salivary adenoid cystic carcinoma than in normal salivary tissues(P<0.05).
  • CONCLUSIONS: MPF highly expressed in salivary adenoid cystic carcinoma, salivary adenoid cystic carcinoma correlated with the expression of MPF and the abnormal activation of MPF was one of the factors for the proliferation of salivary adenoid cystic carcinoma.
  • Metastasis in salivary adenoid cystic carcinoma correlated with the expression of MPF.
  • [MeSH-major] Carcinoma, Adenoid Cystic / metabolism. Maturation-Promoting Factor / metabolism. Salivary Gland Neoplasms / metabolism

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17660907.001).
  • [ISSN] 1006-7248
  • [Journal-full-title] Shanghai kou qiang yi xue = Shanghai journal of stomatology
  • [ISO-abbreviation] Shanghai Kou Qiang Yi Xue
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] EC 2.7.11.22 / Maturation-Promoting Factor
  •  go-up   go-down


62. Darling MR, Jackson-Boeters L, Daley TD, Diamandis EP: Human kallikrein 13 expression in salivary gland tumors. Int J Biol Markers; 2006 Apr-Jun;21(2):106-10
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Human kallikrein 13 expression in salivary gland tumors.
  • Petraki et al have previously described presence of hK13 in salivary gland tissue, localized to duct epithelia and some acinar cells.
  • The aim of this study was to determine whether hK13 is expressed in salivary gland tissues and salivary gland tumors (both benign and malignant), in order to compare normal with tumor tissues.
  • Pleomorphic adenomas (PA), adenoid cystic carcinomas (ACC), polymorphous low grade adenocarcinomas (PLGA), acinic cell carcinomas (ACI), mucoepidermoid carcinomas (MEC) and adenocarcinomas not otherwise specified (ANOS) of both minor and major salivary glands were examined.
  • The results of this study indicate that most salivary gland tumors show high levels of expression of hK13.
  • Overall, staining in PA was significantly less than that seen in normal salivary gland tissue.
  • PLGA, ACC and ANOS each stained significantly more than normal salivary gland tissue while MEC and ACI did not.
  • In conclusion, we demonstrate the high expression of hK13 in several common salivary gland tumors.
  • [MeSH-major] Biomarkers, Tumor. Carcinoma, Adenoid Cystic / metabolism. Gene Expression Regulation, Neoplastic. Kallikreins / biosynthesis. Mouth Mucosa / metabolism. Salivary Gland Neoplasms / genetics
  • [MeSH-minor] Adenocarcinoma / metabolism. Adenoma, Pleomorphic / metabolism. Carcinoma, Mucoepidermoid / metabolism. Humans. Immunohistochemistry. Prognosis. Salivary Glands / metabolism

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16847813.001).
  • [ISSN] 0393-6155
  • [Journal-full-title] The International journal of biological markers
  • [ISO-abbreviation] Int. J. Biol. Markers
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 3.4.21.- / KLK13 protein, human; EC 3.4.21.- / Kallikreins
  •  go-up   go-down


63. Lyons AJ, Xie JJ: Integrins in metastatic adenoid cystic carcinoma. Int J Oral Maxillofac Surg; 2005 Dec;34(8):912-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Integrins in metastatic adenoid cystic carcinoma.
  • Adenoid cystic carcinoma exhibits a diverse clinical behaviour from very localised invasion to widespread metastatases.
  • Recently two adenoid cystic carcinoma cells lines have been isolated and cultured which distinctly show either a low metastatic tendency (Acc-2) or a highly metastatic behaviour (Acc-M).
  • Adenoid cystic carcinoma cells of both types were obtained and successfully cultured.
  • [MeSH-major] Carcinoma, Adenoid Cystic / metabolism. Carcinoma, Adenoid Cystic / secondary. Integrins / biosynthesis. Salivary Gland Neoplasms / metabolism. Salivary Gland Neoplasms / secondary

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16111868.001).
  • [ISSN] 1399-0020
  • [Journal-full-title] International journal of oral and maxillofacial surgery
  • [ISO-abbreviation] Int J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Integrins
  •  go-up   go-down


64. Vargas PA, Cheng Y, Barrett AW, Craig GT, Speight PM: Expression of Mcm-2, Ki-67 and geminin in benign and malignant salivary gland tumours. J Oral Pathol Med; 2008 May;37(5):309-18
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of Mcm-2, Ki-67 and geminin in benign and malignant salivary gland tumours.
  • BACKGROUND: Recent studies have proposed that minichromosome maintenance (Mcm) proteins may be sensitive proliferation markers and may serve as novel biomarkers for prognostication and diagnosis of various pre-malignant and malignant lesions.
  • The aims of this study were to determine the expression of Mcm-2, Ki-67 and geminin in salivary gland (SG) tumours, and to evaluate their usefulness for diagnosis or for prediction of tumour behaviour.
  • There were 13 adenoid cystic carcinomas (ACC), 10 carcinoma ex pleomorphic adenomas (CEPA), 10 mucoepidermoid carcinomas (MEC), 10 polymorphous low-grade adenocarcinomas (PLGA), 10 pleomorphic adenomas (PA) and nine acinic cell carcinomas (AcCC).
  • CONCLUSIONS: The findings suggest that Mcm-2 may be a sensitive proliferation marker in SG tumours and may be useful for differential diagnosis between PA and CEPA, and ACC and PLGA.
  • [MeSH-major] Biomarkers, Tumor / biosynthesis. Cell Cycle Proteins / biosynthesis. Ki-67 Antigen / biosynthesis. Nuclear Proteins / biosynthesis. Salivary Gland Neoplasms / metabolism
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / metabolism. Adenoma, Pleomorphic / diagnosis. Adenoma, Pleomorphic / metabolism. Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Acinar Cell / diagnosis. Carcinoma, Acinar Cell / metabolism. Carcinoma, Adenoid Cystic / diagnosis. Carcinoma, Adenoid Cystic / metabolism. Carcinoma, Mucoepidermoid / diagnosis. Carcinoma, Mucoepidermoid / metabolism. Cell Proliferation. Diagnosis, Differential. Female. Geminin. Humans. Immunoenzyme Techniques. Male. Microarray Analysis. Middle Aged. Minichromosome Maintenance Complex Component 2. Neoplasm Proteins / biosynthesis

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18248354.001).
  • [ISSN] 1600-0714
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Cell Cycle Proteins; 0 / GMNN protein, human; 0 / Geminin; 0 / Ki-67 Antigen; 0 / Neoplasm Proteins; 0 / Nuclear Proteins; EC 3.6.4.12 / MCM2 protein, human; EC 3.6.4.12 / Minichromosome Maintenance Complex Component 2
  •  go-up   go-down


65. Chandana SR, Conley BA: Salivary gland cancers: current treatments, molecular characteristics and new therapies. Expert Rev Anticancer Ther; 2008 Apr;8(4):645-52
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Salivary gland cancers: current treatments, molecular characteristics and new therapies.
  • Salivary gland cancers are relatively rare and quite diverse.
  • This article reviews the epidemiology, staging, molecular characteristics, and treatment evidence for the most common types of salivary cancers and suggests potential future diagnostic and treatment directions.
  • Progress in understanding the molecular and cell biology of salivary gland cancers may lead to the development of targeted therapies in these rare tumors.
  • Multidisciplinary and multi-institutional collaborative studies are needed to help improve survival in salivary gland cancers.
  • [MeSH-major] Adenocarcinoma. Salivary Gland Neoplasms
  • [MeSH-minor] Carcinoma, Adenoid Cystic / drug therapy. Carcinoma, Adenoid Cystic / genetics. Carcinoma, Adenoid Cystic / radiography. Carcinoma, Adenoid Cystic / surgery. Carcinoma, Mucoepidermoid / drug therapy. Carcinoma, Mucoepidermoid / genetics. Carcinoma, Mucoepidermoid / radiography. Carcinoma, Mucoepidermoid / surgery. Humans. Mutation. Prognosis. Radiotherapy, Adjuvant

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18402531.001).
  • [ISSN] 1744-8328
  • [Journal-full-title] Expert review of anticancer therapy
  • [ISO-abbreviation] Expert Rev Anticancer Ther
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 81
  •  go-up   go-down


66. Tang Y, Liang X, Zheng M, Zhu Z, Zhu G, Yang J, Chen Y: Expression of c-kit and Slug correlates with invasion and metastasis of salivary adenoid cystic carcinoma. Oral Oncol; 2010 Apr;46(4):311-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of c-kit and Slug correlates with invasion and metastasis of salivary adenoid cystic carcinoma.
  • The overexpression of c-kit seems to be frequent and specific in salivary adenoid cystic carcinoma (ACC), however, there is little information on correlation between c-kit expression and the invasion and metastasis.
  • These findings indicated that c-kit/Slug pathway might participate in the invasion and metastasis of salivary ACC.
  • [MeSH-major] Adenocarcinoma. Carcinoma, Adenoid Cystic. Neoplasm Proteins / metabolism. Proto-Oncogene Proteins c-kit / metabolism. Salivary Gland Neoplasms. Transcription Factors / metabolism

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2010 Elsevier Ltd. All rights reserved.
  • (PMID = 20219417.001).
  • [ISSN] 1879-0593
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Neoplasm Proteins; 0 / Transcription Factors; 0 / snail family transcription factors; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
  •  go-up   go-down


67. Elkin AD, Jacobs CD: Tamoxifen for salivary gland adenoid cystic carcinoma: report of two cases. J Cancer Res Clin Oncol; 2008 Oct;134(10):1151-3
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tamoxifen for salivary gland adenoid cystic carcinoma: report of two cases.
  • PURPOSE: Adenoid cystic carcinoma of the salivary gland (ACC-SG) is a slow-growing tumor that is refractory to most chemotherapeutic agents.
  • [MeSH-major] Antineoplastic Agents, Hormonal / therapeutic use. Carcinoma, Adenoid Cystic / drug therapy. Salivary Gland Neoplasms / drug therapy. Tamoxifen / therapeutic use

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. TAMOXIFEN .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Am J Clin Pathol. 2003 Jun;119(6):801-6 [12817426.001]
  • [Cites] Oral Oncol. 2000 Sep;36(5):450-3 [10964052.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 1987 Oct;113(10):1082-5 [3620130.001]
  • [Cites] Laryngoscope. 2001 Aug;111(8):1434-9 [11568581.001]
  • [Cites] Clin Cancer Res. 2000 Nov;6(11):4359-64 [11106254.001]
  • [Cites] Eur J Surg Oncol. 2001 Dec;27(8):714-8 [11735166.001]
  • [Cites] Int J Oral Maxillofac Surg. 2004 Jan;33(1):25-31 [14690656.001]
  • [Cites] Cancer Res. 2003 Dec 15;63(24):8742-8 [14695189.001]
  • [Cites] Oral Oncol. 2005 Oct;41(9):890-4 [16043380.001]
  • [Cites] J Natl Cancer Inst. 1996 Mar 6;88(5):279-84 [8614006.001]
  • [Cites] Curr Med Chem Anticancer Agents. 2004 Nov;4(6):543-51 [15579019.001]
  • [Cites] Am J Surg. 1997 Nov;174(5):495-8 [9374223.001]
  • [Cites] J Laryngol Otol. 1997 Dec;111(12):1186-9 [9509115.001]
  • [Cites] J Surg Oncol. 2005 May 1;90(2):77-80 [15844191.001]
  • (PMID = 18347813.001).
  • [ISSN] 0171-5216
  • [Journal-full-title] Journal of cancer research and clinical oncology
  • [ISO-abbreviation] J. Cancer Res. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Hormonal; 094ZI81Y45 / Tamoxifen; 7NFE54O27T / Toremifene
  •  go-up   go-down


68. Ma J, Wang J, Zhong M, Wang ZY: [Effects of genistein on the expressions of cell apoptosis-related proteins in salivary adenoid cystic carcinoma cell line SACC-83]. Shanghai Kou Qiang Yi Xue; 2008 Apr;17(2):196-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Effects of genistein on the expressions of cell apoptosis-related proteins in salivary adenoid cystic carcinoma cell line SACC-83].
  • PURPOSE: To investigate the molecular mechanism of cell apoptosis induced by tyrosine protein kinase inhibitor, genistein, in human salivary adenoid cystic carcinoma cell line SACC-83.
  • CONCLUSION: The cell apoptosis induced by genistein in human salivary adenoid cystic carcinoma cell line SACC-83 may be associated with the upregulation of bax protein expression,and the downregulations of bcl-2 and survivin proteins expression.
  • [MeSH-major] Carcinoma, Adenoid Cystic / metabolism. Genistein / pharmacology. Salivary Gland Neoplasms / metabolism

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • Hazardous Substances Data Bank. GENISTEIN .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18470428.001).
  • [ISSN] 1006-7248
  • [Journal-full-title] Shanghai kou qiang yi xue = Shanghai journal of stomatology
  • [ISO-abbreviation] Shanghai Kou Qiang Yi Xue
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Proteins; DH2M523P0H / Genistein
  •  go-up   go-down


69. Huang FH, Tian Z, Zhang CY, Xia RH, Li J: [Effect of DNA methyltransferases 1 inhibition on proliferation, invasion, and metastasis in ACC-M line]. Zhonghua Kou Qiang Yi Xue Za Zhi; 2009 Dec;44(12):745-50
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To investigate the effect of DNA methyltransferases 1 (DNMT-1) inhibition on the ACC-M cells in vitro and in vivo and discuss the role of DNMT-1 in the development, invasion and metastasis of salivary adenoid cystic carcinoma (SACC).
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Repressor Proteins / antagonists & inhibitors. Salivary Gland Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20193293.001).
  • [ISSN] 1002-0098
  • [Journal-full-title] Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
  • [ISO-abbreviation] Zhonghua Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / DMAP1 protein, human; 0 / Repressor Proteins
  •  go-up   go-down


70. Dequanter D, Andry G, Lothaire P, Larsimont D, Deraemaecker R: Wide localized excision and reconstruction for minor salivary gland tumours. B-ENT; 2005;1(4):187-90
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Wide localized excision and reconstruction for minor salivary gland tumours.
  • BACKGROUND: Insufficient excision is one of the main factors leading to recurrence of minor salivary gland tumours.
  • METHODS: Four consecutive patients suffering from minor salivary gland tumours of the upper aerodigestive tract were treated: two had adenoid cystic carcinomas (one of the lateral oropharyngeal mucosa, one of the retromolar area); one had a polymorphous low-grade carcinoma (at the base of the tongue); and one had mucoepidermoid carcinoma (on the floor of the mouth).
  • Two patients, locally controlled, with adenoid cystic carcinomas died: one from brain metastases (four years post-surgery), the other with pulmonary metastases (eight-years post-surgery).
  • CONCLUSIONS: For minor salivary gland carcinoma of the head and neck, large resection with immediate reconstruction affords fast recovery and long-lasting locoregional control.
  • [MeSH-major] Carcinoma, Adenoid Cystic / surgery. Carcinoma, Mucoepidermoid / surgery. Neck Dissection / methods. Reconstructive Surgical Procedures / methods. Salivary Gland Neoplasms / surgery

  • MedlinePlus Health Information. consumer health - Plastic and Cosmetic Surgery.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16429751.001).
  • [ISSN] 1781-782X
  • [Journal-full-title] B-ENT
  • [ISO-abbreviation] B-ENT
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Belgium
  •  go-up   go-down


71. Teymoortash A, Ramaswamy A, Werner JA: [Adenoid cystic carcinoma secondary to heterotopic salivary gland tissue of the cervical lymph nodes]. Laryngorhinootologie; 2007 Jan;86(1):44-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Adenoid cystic carcinoma secondary to heterotopic salivary gland tissue of the cervical lymph nodes].
  • [Transliterated title] Adenoidzystisches Karzinom im heterotopen Speicheldrüsengewebe der zervikalen Lymphknoten.
  • BACKGROUND: The presence of heterotopic salivary gland tissue in intra-, periparotideal and cervical lymph nodes is not an uncommen finding.
  • In some rare cases the salivary gland inclusions in lymph nodes may undergo neoplastic transformation.
  • The histological assessment of the extirpated node seemed to indicate lymph node metastasis of an adenoid cystic carcinoma.
  • RESULTS: Due to the fact of missing of a primary tumor, the diagnosis of an adenoid cystic carcinoma in heterotopic salivary gland tissue of the cervical lymph node was established after long-term observation.
  • CONCLUSION: After exclusion of an occult carcinoma of the salivary glands, the possibility of malignant transformation of heterotopic intranodal salivary gland inclusions should be considered in patients suffering from salivary gland carcinoma in the area of the cervical lymph nodes.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Cell Transformation, Neoplastic / pathology. Choristoma / pathology. Lymph Nodes / pathology. Otorhinolaryngologic Neoplasms / pathology. Salivary Glands
  • [MeSH-minor] Diagnosis, Differential. Humans. Lymph Node Excision. Male. Middle Aged

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16586289.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


72. Singh S, Gokkulakrishnan, Jain J, Pathak S, Singh KT: Adenoid cystic carcinoma of buccal mucosa. J Maxillofac Oral Surg; 2010 Sep;9(3):273-6
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenoid cystic carcinoma of buccal mucosa.
  • Adenoid cystic carcinoma is a malignant neoplasm most commonly originating in salivary glands of head and neck region.
  • Here we present a case report of a 50 year old male who was diagnosed with adenoid cystic carcinoma of the right buccal mucosa.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 22190804.001).
  • [ISSN] 0974-942X
  • [Journal-full-title] Journal of maxillofacial and oral surgery
  • [ISO-abbreviation] J Maxillofac Oral Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3177452
  • [Keywords] NOTNLM ; Adenoid cystic / Carcinoma / Malignant neoplasm / Salivary gland disorder
  •  go-up   go-down


73. Takahira M, Minato H, Takahashi M, Karino K, Sugiyama K: Cystic carcinoma ex pleomorphic adenoma of the lacrimal gland. Ophthal Plast Reconstr Surg; 2007 Sep-Oct;23(5):407-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cystic carcinoma ex pleomorphic adenoma of the lacrimal gland.
  • The tumor was diagnosed as a carcinoma ex pleomorphic adenoma of the lacrimal gland.
  • The carcinoma cells showed positive immunoreactivity for androgen receptor and BRST-2, indicating that the tumor was equivalent to a salivary duct carcinoma.
  • This case demonstrates that a carcinoma ex pleomorphic adenoma of the lacrimal gland may develop in a cyst.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Carcinoma, Adenoid Cystic / pathology. Eye Neoplasms / pathology. Lacrimal Apparatus Diseases / pathology

  • MedlinePlus Health Information. consumer health - Eye Cancer.
  • MedlinePlus Health Information. consumer health - Tears.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17881995.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


74. Jaeger RG, Scarabotto-Neto N, Azambuja N Jr, Freitas VM: Secretion of collagen I and tenascin is modulated by laminin-111 in 3D culture of human adenoid cystic carcinoma cells. Int J Exp Pathol; 2008 Apr;89(2):98-105
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Secretion of collagen I and tenascin is modulated by laminin-111 in 3D culture of human adenoid cystic carcinoma cells.
  • Adenoid cystic carcinoma is a frequent malignant salivary gland neoplasm with high levels of recurrence and metastasis.
  • We are studying regulatory mechanisms underlying secretion of ECM molecules in adenoid cystic carcinoma.
  • We have previously demonstrated that laminin modulates the phenotype of a human adenoid cystic carcinoma (CAC2) cell line.
  • We suggest that laminin-111 modulates secretion of collagen I and tenascin in cells derived from human adenoid cystic carcinoma.
  • [MeSH-major] Carcinoma, Adenoid Cystic / secretion. Collagen Type I / secretion. Laminin / pharmacology. Neoplasm Proteins / secretion. Tenascin / secretion

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Matrix Biol. 2000 Dec;19(7):581-96 [11102748.001]
  • [Cites] Oral Oncol. 2007 Nov;43(10):987-98 [17257887.001]
  • [Cites] Oral Oncol. 2001 Dec;37(8):638-42 [11590073.001]
  • [Cites] Virchows Arch. 2001 Oct;439(4):571-8 [11710645.001]
  • [Cites] Virchows Arch. 2002 Dec;441(6):569-76 [12461614.001]
  • [Cites] J Oral Pathol Med. 2003 May;32(5):290-6 [12694353.001]
  • [Cites] Oral Oncol. 2004 Jan;40(1):36-42 [14662413.001]
  • [Cites] Oral Oncol. 2004 May;40(5):483-9 [15006619.001]
  • [Cites] Hum Pathol. 1983 Sep;14(9):780-97 [6309645.001]
  • [Cites] Hum Pathol. 1983 Sep;14(9):798-809 [6309646.001]
  • [Cites] Oral Oncol. 2000 Mar;36(2):248-52 [10745180.001]
  • [Cites] Dev Dyn. 2000 Jun;218(2):235-59 [10842355.001]
  • [Cites] Histopathology. 2000 Aug;37(2):118-23 [10931234.001]
  • [Cites] J Oral Pathol. 1986 Jul;15(6):308-18 [2428959.001]
  • [Cites] Cancer. 1992 Jun 1;69(11):2631-40 [1315206.001]
  • [Cites] Virchows Arch A Pathol Anat Histopathol. 1992;420(5):425-31 [1375797.001]
  • [Cites] Cancer. 1992 Jul 15;70(2):379-85 [1617588.001]
  • [Cites] Experientia. 1995 Mar 15;51(3):194-5 [7698270.001]
  • [Cites] Virchows Arch. 1995;426(6):577-86 [7655738.001]
  • [Cites] Curr Biol. 1996 Jun 1;6(6):645-7 [8793283.001]
  • [Cites] J Cell Biol. 1997 Apr 7;137(1):231-45 [9105051.001]
  • [Cites] Cancer Lett. 1997 Jun 3;116(1):9-14 [9177451.001]
  • [Cites] Virchows Arch. 1997 Jun;430(6):467-77 [9230912.001]
  • [Cites] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1997 Dec;84(6):663-7 [9431536.001]
  • [Cites] Int J Biochem Cell Biol. 2005 May;37(5):1066-83 [15743679.001]
  • [Cites] J Cell Sci. 2005 Apr 1;118(Pt 7):1341-53 [15788652.001]
  • [Cites] Matrix Biol. 2005 Aug;24(5):326-32 [15979864.001]
  • [Cites] Cancer Lett. 2006 Dec 8;244(2):143-63 [16632194.001]
  • [Cites] Matrix Biol. 2007 Apr;26(3):146-55 [17141492.001]
  • [Cites] Am J Pathol. 2007 Jul;171(1):124-38 [17591960.001]
  • [Cites] Matrix Biol. 2001 Sep;20(5-6):337-45 [11566268.001]
  • (PMID = 18336527.001).
  • [ISSN] 1365-2613
  • [Journal-full-title] International journal of experimental pathology
  • [ISO-abbreviation] Int J Exp Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Collagen Type I; 0 / Gels; 0 / Laminin; 0 / Neoplasm Proteins; 0 / Tenascin; 0 / laminin 1
  • [Other-IDs] NLM/ PMC2525767
  •  go-up   go-down


75. Liu X, Zhang Y, Ren W, Cao T, Zhu Y: RNAi knockdown of C-erbB2 expression inhibits salivary gland adenoid cystic carcinoma SACC-83 cell growth in vitro. J Biomed Res; 2010 May;24(3):215-22
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] RNAi knockdown of C-erbB2 expression inhibits salivary gland adenoid cystic carcinoma SACC-83 cell growth in vitro.
  • OBJECTIVE: To knockdown the C-erbB2 gene in salivary gland adenoid cystic carcinoma SACC-83 cells using RNA interference, and determine the effect of silencing C-erbB2 on cell proliferation.
  • RESULTS: Compared with the control, C-erbB2 mRNA expression was decreased in the C-erbB2-siRNA transfection group, and immunohistochemical analysis indicated that C-erbB2 protein expression was decreased.
  • The differences were statistically significant (P < 0.05) between the C-erbB2-siRNA group and the control groups.
  • Following the C-erbB2 knockdown, the percentage of apoptotic cells was 5.63% compared with 2.04%, 2.85%, and 2.98% in the three control groups, respectively.
  • CONCLUSION: RNA interference can effectively silence C-erbB2 gene expression and inhibit growth of SACC-83 cells, which indicates the potential of targeting this gene as a novel gene therapy approach for the treatment of salivary gland adenoid cystic carcinoma.

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 23554633.001).
  • [ISSN] 1674-8301
  • [Journal-full-title] Journal of biomedical research
  • [ISO-abbreviation] J Biomed Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC3596557
  • [Keywords] NOTNLM ; C-erbB2 / RNA interference / gene silence / salivary gland adenoid cystic carcinoma
  •  go-up   go-down


76. Morais Freitas V, Nogueira da Gama de Souza L, Cyreno Oliveira E, Furuse C, Cavalcanti de Araújo V, Gastaldoni Jaeger R: Malignancy-related 67kDa laminin receptor in adenoid cystic carcinoma. Effect on migration and beta-catenin expression. Oral Oncol; 2007 Nov;43(10):987-98
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignancy-related 67kDa laminin receptor in adenoid cystic carcinoma. Effect on migration and beta-catenin expression.
  • Adenoid cystic carcinoma is a malignant salivary gland neoplasm with recurrence and metastasis.
  • Immunohistochemistry showed 67LR in adenoid cystic carcinoma.
  • We studied the effect of 67LR and YIGSR in cells (CAC2) from adenoid cystic carcinoma.
  • [MeSH-major] Carcinoma, Adenoid Cystic / metabolism. Laminin / metabolism. Neoplasm Proteins / metabolism. Receptors, Laminin / metabolism. Salivary Gland Neoplasms / metabolism

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17257887.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Laminin; 0 / Neoplasm Proteins; 0 / Oligopeptides; 0 / Receptors, Laminin; 110590-64-2 / tyrosyl-isoleucyl-glycyl-seryl-arginine
  •  go-up   go-down


77. Paleri V, Robinson M, Bradley P: Polymorphous low-grade adenocarcinoma of the head and neck. Curr Opin Otolaryngol Head Neck Surg; 2008 Apr;16(2):163-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Polymorphous low-grade adenocarcinoma of the head and neck.
  • PURPOSE OF REVIEW: Polymorphous low-grade adenocarcinoma is an entity described in 1984.
  • An increasing number of reports in the pathology literature since then have identified this as the second or the third most common minor salivary gland malignancy.
  • The natural history of polymorphous low-grade adenocarcinoma is distinct from other malignant salivary tumours.
  • RECENT FINDINGS: Polymorphous low-grade adenocarcinoma is a slow-growing tumour that is locally invasive.
  • Diagnosis is established after a biopsy because cytological studies are not helpful.
  • The morphological features can resemble pleomorphic adenoma and adenoid cystic carcinoma.
  • The role of radiation therapy is not clear in the management of polymorphous low-grade adenocarcinoma.
  • SUMMARY: Polymorphous low-grade adenocarcinoma is primarily a pathologic diagnosis.
  • [MeSH-major] Adenocarcinoma / pathology. Salivary Gland Neoplasms / pathology

  • Genetic Alliance. consumer health - Polymorphous low-grade adenocarcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18327037.001).
  • [ISSN] 1531-6998
  • [Journal-full-title] Current opinion in otolaryngology & head and neck surgery
  • [ISO-abbreviation] Curr Opin Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 60
  •  go-up   go-down


78. Crain N, Nelson BL, Barnes EL, Thompson LD: Ceruminous gland carcinomas: a clinicopathologic and immunophenotypic study of 17 cases. Head Neck Pathol; 2009 Mar;3(1):1-17
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ceruminous gland carcinomas: a clinicopathologic and immunophenotypic study of 17 cases.
  • BACKGROUND: Ceruminal gland carcinomas are rare neoplasms confined to the skin lining the cartilaginous part of the external auditory canal.
  • Histologically, the tumors demonstrated a solid to cystic pattern, composed of an infiltrating glandular to cribriform arrangement of epithelial cells.
  • Tumors were divided into three types of adenocarcinoma based on pattern of growth and cell type (ceruminous, NOS [n = 12], adenoid cystic [n = 4], mucoepidermoid [n = 1]).
  • CK7 and CD117 highlighted the luminal cells, while S1-00 protein showed a predilection for the basal cells of ceruminous and adenoid cystic carcinomas.
  • Metastatic adenocarcinoma or direct extension from salivary gland neoplasms are the principle differential considerations.
  • CONCLUSION: Ceruminous-type carcinomas, with the exception of ceruminous mucoepidermoid carcinoma, all demonstrated a dual cell population of basal myoepithelial-type cells and luminal apocrine cells.
  • [MeSH-major] Carcinoma / pathology. Ear Neoplasms / pathology. Ear, External / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] J Thorac Cardiovasc Surg. 1973 Jun;65(6):909-13 [4350087.001]
  • [Cites] J Laryngol Otol. 1973 Dec;87(12):1201-10 [4357381.001]
  • [Cites] J Laryngol Otol. 1974 Apr;88(4):363-8 [4824672.001]
  • [Cites] Can J Otolaryngol. 1974;3(2):194-201 [4831936.001]
  • [Cites] Arch Otolaryngol. 1974 Nov;100(5):395-7 [4429488.001]
  • [Cites] Cancer. 1975 Sep;36(3):1072-6 [171051.001]
  • [Cites] J Laryngol Otol. 1975 Jul;89(7):707-20 [171328.001]
  • [Cites] Arch Otolaryngol. 1975 Nov;101(11):702-5 [1200915.001]
  • [Cites] Laryngoscope. 1977 Oct;87(10 Pt 1):1601-12 [198620.001]
  • [Cites] J Can Assoc Radiol. 1977 Dec;28(4):287-90 [303644.001]
  • [Cites] Cancer. 1978 Feb;41(2):545-53 [630537.001]
  • [Cites] Arch Otolaryngol. 1980 Jan;106(1):13-9 [6243462.001]
  • [Cites] Ann Otol Rhinol Laryngol. 1990 Sep;99(9 Pt 1):714-21 [2396807.001]
  • [Cites] Neurol Med Chir (Tokyo). 1990 Dec;30(13):1034-7 [1714051.001]
  • [Cites] Otolaryngol Head Neck Surg. 1992 Feb;106(2):214-5 [1310808.001]
  • [Cites] Acta Morphol Hung. 1991;39(2):157-65 [1789146.001]
  • [Cites] J Laryngol Otol. 1992 Aug;106(8):727-32 [1328435.001]
  • [Cites] Pathology. 1992 Oct;24(4):315-9 [1337771.001]
  • [Cites] Rev Laryngol Otol Rhinol (Bord). 1993;114(1):49-52 [8191051.001]
  • [Cites] J Laryngol Otol. 1994 Aug;108(8):706-9 [7930929.001]
  • [Cites] Cancer. 1982 Dec 15;50(12):2873-83 [6291744.001]
  • [Cites] J Laryngol Otol. 1995 Mar;109(3):180-8 [7745330.001]
  • [Cites] Am J Dermatopathol. 1995 Apr;17(2):169-73 [8600783.001]
  • [Cites] J Laryngol Otol. 1996 Mar;110(3):249-51 [8730361.001]
  • [Cites] J Am Anim Hosp Assoc. 1996 Sep-Oct;32(5):448-52 [8875362.001]
  • [Cites] Indian J Cancer. 1997 Sep;34(3):139-42 [9491676.001]
  • [Cites] Br J Plast Surg. 1998 Jun;51(4):317-20 [9771352.001]
  • [Cites] J Laryngol Otol. 1957 Dec;71(12):824-31 [13491925.001]
  • [Cites] J Laryngol Otol. 1957 Dec;71(12):832-7 [13491926.001]
  • [Cites] Cancer. 1964 Jan;17:67-75 [14102073.001]
  • [Cites] J Otolaryngol. 1980 Dec;9(6):482-6 [6162967.001]
  • [Cites] J Laryngol Otol. 1981 Aug;95(8):843-8 [6267150.001]
  • [Cites] J Neurosurg. 1981 Dec;55(6):952-6 [7299469.001]
  • [Cites] Am J Clin Pathol. 1982 Feb;77(2):153-61 [7039299.001]
  • [Cites] Laryngoscope. 1983 Mar;93(3):326-40 [6300574.001]
  • [Cites] Hiroshima J Med Sci. 1984 Mar;33(1):17-22 [6090347.001]
  • [Cites] J Am Acad Dermatol. 1984 Nov;11(5 Pt 1):841-7 [6096419.001]
  • [Cites] Laryngoscope. 1987 Feb;97(2):158-64 [3807618.001]
  • [Cites] Am J Otol. 1987 Nov;8(6):485-8 [3434612.001]
  • [Cites] Cancer. 1989 Dec 1;64(11):2292-302 [2804921.001]
  • [Cites] J R Soc Med. 1990 Jan;83(1):34-7 [2406442.001]
  • [Cites] J Laryngol Otol. 1999 Jun;113(6):578-80 [10605594.001]
  • [Cites] J Otolaryngol. 2001 Dec;30(6):373-7 [11771014.001]
  • [Cites] Arch Pathol Lab Med. 2002 Jan;126(1):87-9 [11800656.001]
  • [Cites] J Oral Maxillofac Surg. 2002 Apr;60(4):465-9 [11928113.001]
  • [Cites] Mod Pathol. 2002 May;15(5):543-55 [12011260.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 2002 Jul;128(7):834-7 [12117346.001]
  • [Cites] ORL J Otorhinolaryngol Relat Spec. 2002 Sep-Oct;64(5):358-63 [12417781.001]
  • [Cites] J Laryngol Otol. 2003 Mar;117(3):202-4 [12648377.001]
  • [Cites] Am J Otolaryngol. 2003 Jul-Aug;24(4):274-7 [12884224.001]
  • [Cites] Acta Otorhinolaryngol Ital. 2004 Dec;24(6):354-6 [15952686.001]
  • [Cites] Ear Nose Throat J. 2005 Sep;84(9):560-1 [16261754.001]
  • [Cites] Otol Neurotol. 2006 Jan;27(1):97-101 [16371854.001]
  • [Cites] Indian J Pathol Microbiol. 2006 Oct;49(4):587-9 [17183866.001]
  • [Cites] Acta Otolaryngol. 2007 Mar;127(3):280-4 [17364365.001]
  • [Cites] Otolaryngol Head Neck Surg. 2007 Dec;137(6):893-8 [18036417.001]
  • [Cites] J Neurosurg. 2008 Jan;108(1):97-104 [18173317.001]
  • [Cites] B-ENT. 2007;3(4):195-9 [18265725.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 2008 Jun;134(6):663-6 [18559737.001]
  • [Cites] Laryngoscope. 2008 Sep;118(9):1591-6 [18677277.001]
  • [Cites] Auris Nasus Larynx. 2003 Aug;30(3):287-90 [12927294.001]
  • [Cites] Acta Cytol. 2003 Sep-Oct;47(5):792-4 [14526681.001]
  • [Cites] ORL J Otorhinolaryngol Relat Spec. 2003 Sep-Oct;65(5):300-2 [14730188.001]
  • [Cites] J Laryngol Otol. 2003 Dec;117(12):951-4 [14738604.001]
  • [Cites] Am J Surg Pathol. 2004 Mar;28(3):308-18 [15104293.001]
  • [Cites] Arch Otolaryngol. 1967 Jul;86(1):66-9 [6026961.001]
  • [Cites] Arch Dermatol. 1968 Oct;98(4):344-8 [4300211.001]
  • [Cites] Arch Otolaryngol. 1970 Jul;92(1):40-2 [4192890.001]
  • [Cites] J Laryngol Otol. 1970 Jul;84(7):743-5 [5432829.001]
  • [Cites] Pract Otorhinolaryngol (Basel). 1970;32(4):211-8 [5477506.001]
  • [Cites] Cancer. 1971 Sep;28(3):775-80 [4328926.001]
  • [Cites] Tex Med. 1970 Oct;66(10):56-9 [4335213.001]
  • [Cites] Cancer. 1972 May;29(5):1169-78 [5021609.001]
  • (PMID = 20596983.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ PMC2807538
  • [Keywords] NOTNLM ; Adenoid cystic / Carcinoma / Ceruminal / Ceruminous / Ear / Gland / Immunohistochemistry / Mucoepidermoid / Prognosis
  •  go-up   go-down


79. Ettl T, Schwarz S, Kühnel T, Stockmann P, Reichert TE, Driemel O: [Prognostic value of immunohistochemistry in salivary gland cancer]. HNO; 2008 Feb;56(2):231-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Prognostic value of immunohistochemistry in salivary gland cancer].
  • BACKGROUND: The diversity of salivary gland malignancies as to morphology and clinical course makes it difficult to establish prognostic factors.
  • The aim of this study was to evaluate the prognostic significance of, a. o., immunohistochemical criteria in a retrospective study of salivary gland cancer.
  • PATIENTS AND METHODS: Clinical and histologic data were recorded for 101 patients with carcinomas of the salivary glands.
  • RESULTS: Findings included the following: an association between loss of maspin and the presence of nodal metastasis, residual tumour, and poor overall survival for adenoid cystic carcinoma; common C-KIT expression in adenoid cystic carcinoma (92%); correlation of loss of C-KIT with high malignancy grade, nodal metastases, high proliferative activity (Ki-67>30%), and unfavourable survival in all tumours; common HER2 expression (83%) in salivary duct carcinoma but no relation to the total collective's survival.
  • High proliferative activity (Ki-67>30%) is the strongest negative predictor in salivary gland cancer.
  • Besides well-known clinicopathological factors, current immunohistochemical markers such as maspin, EGFR, and C-KIT can contribute to establish prognosis in salivary gland cancer.
  • [MeSH-major] Biomarkers, Tumor / analysis. Neoplasm Proteins / analysis. Risk Assessment / methods. Salivary Gland Neoplasms / diagnosis. Salivary Gland Neoplasms / mortality


80. Liu T, Lin B, Qin J: Carcinoma-associated fibroblasts promoted tumor spheroid invasion on a microfluidic 3D co-culture device. Lab Chip; 2010 Jul 7;10(13):1671-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Carcinoma-associated fibroblasts promoted tumor spheroid invasion on a microfluidic 3D co-culture device.
  • Carcinoma-associated fibroblasts (CAFs) are a key determinant in malignant progression of cancer and represent an important target for cancer therapies.
  • In this work, we present a microfluidic-based 3D co-culture device to reconstruct an in vitro tumor microenvironment and firstly investigate the effect of CAFs on cancer cell invasion in 3D matrix.
  • Salivary gland adenoid cystic carcinoma (ACC) cells and CAFs embedded in matrix were co-cultured without direct contact on the device.
  • It was observed that CAFs promoted ACC cell invasion in 3D matrix in a spheroid fashion, indicating that CAFs play a critical role in cancer invasion.
  • We further demonstrated the effect of MMP inhibitor as an agent against CAF-promoted cancer invasion.
  • Thus, it provides a suitable platform for elucidating the mechanism of CAF-regulated cancer invasion and discovering anti-invasion drugs in a well defined 3D environment.
  • [MeSH-major] Carcinoma / pathology. Cell Transformation, Neoplastic / pathology. Coculture Techniques / instrumentation. Fibroblasts / pathology. Microfluidic Analytical Techniques / instrumentation. Spheroids, Cellular / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20414488.001).
  • [ISSN] 1473-0197
  • [Journal-full-title] Lab on a chip
  • [ISO-abbreviation] Lab Chip
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  •  go-up   go-down


81. Talmon GA, Khan A, Koerber R, Lele S, Johansson S: A cribriform urothelial neoplasm of the renal pelvis: an adenoid cysticlike variant of inverted urothelial papilloma or florid ureteritis cystica? Arch Pathol Lab Med; 2010 Oct;134(10):1557-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A cribriform urothelial neoplasm of the renal pelvis: an adenoid cysticlike variant of inverted urothelial papilloma or florid ureteritis cystica?
  • Tumors with cribriform appearance, similar to that of salivary gland adenoid cystic carcinoma, have been described at various anatomic sites.
  • The mass displayed a prominent cribriform architecture, akin to adenoid cystic carcinoma with an immunophenotype that supported a urothelial origin.
  • This cribriform urothelial neoplasm of the renal pelvis may, in fact, represent a variant of an inverted urothelial neoplasm with a prominent cystic component or florid ureteritis cystica.
  • [MeSH-major] Carcinoma, Transitional Cell / pathology. Neoplasms, Connective Tissue / pathology. Papilloma / pathology. Papilloma, Inverted / pathology. Urologic Neoplasms / pathology. Urothelium / pathology
  • [MeSH-minor] Aged, 80 and over. Cell Division. Diagnosis, Differential. Humans. Immunophenotyping / methods. Kidney Pelvis / pathology. Male. Proto-Oncogene Proteins c-kit / analysis. Urinary Bladder Neoplasms / pathology

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20923313.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
  •  go-up   go-down


82. Wang D, Li Y, He H, Liu L, Wu L, He Z: Intraoral minor salivary gland tumors in a Chinese population: a retrospective study on 737 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2007 Jul;104(1):94-100
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intraoral minor salivary gland tumors in a Chinese population: a retrospective study on 737 cases.
  • OBJECTIVES: This study aimed to investigate the diverse histopathological types and distribution characteristics of epithelial minor salivary gland tumors (MSGTs) in a Chinese population.
  • Pleomorphic adenoma (PA) (81.8%) and adenoid cystic carcinoma (ACC) (36.0%) were the most frequent types in benign and malignant tumors, respectively.
  • [MeSH-major] Adenoma, Pleomorphic / epidemiology. Carcinoma, Adenoid Cystic / epidemiology. Salivary Gland Neoplasms / epidemiology. Salivary Glands, Minor

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Feb;105(2):136-8 [18230384.001]
  • (PMID = 17577550.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


83. Nong XL, Xia Y, Yang YP, Qing HY, Li JQ, Li YN, Cao Y, Li H, Chen Q: [Tyrosine kinase A and vascular endothelial growth factor receptor 2 in the invasion and metastasis of salivary adenoid cystic carcinoma]. Hua Xi Kou Qiang Yi Xue Za Zhi; 2010 Aug;28(4):420-4, 429
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Tyrosine kinase A and vascular endothelial growth factor receptor 2 in the invasion and metastasis of salivary adenoid cystic carcinoma].
  • OBJECTIVE: To determine the effect of tyrosine kinase A (TrkA) and vascular endothelial growth factor receptor 2 (VEGFR2) in the invasion and metastasis of salivary adenoid cystic carcinoma (SACC).
  • METHODS: The expression of TrkA and VEGFR2 were detected by immunohistochemical staining in 47 cases of SACC of salivary glands.
  • [MeSH-major] Carcinoma, Adenoid Cystic / metabolism. Receptor, trkA / metabolism. Salivary Gland Neoplasms / metabolism

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20848939.001).
  • [ISSN] 1000-1182
  • [Journal-full-title] Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology
  • [ISO-abbreviation] Hua Xi Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] EC 2.7.10.1 / Receptor, trkA; EC 2.7.10.1 / Vascular Endothelial Growth Factor Receptor-2
  •  go-up   go-down


84. Fukuda M, Kusama K, Sakashita H: Cimetidine inhibits salivary gland tumor cell adhesion to neural cells and induces apoptosis by blocking NCAM expression. BMC Cancer; 2008;8:376
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cimetidine inhibits salivary gland tumor cell adhesion to neural cells and induces apoptosis by blocking NCAM expression.
  • BACKGROUND: Cimetidine, a histamine type-2 receptor antagonist, has been reported to inhibit the growth of glandular tumors such as colorectal cancer, however the mechanism of action underlying this effect is unknown.
  • Adenoid cystic carcinoma is well known as a malignant salivary gland tumor which preferentially invades neural tissues.
  • We demonstrated previously that human salivary gland tumor (HSG) cells spontaneously express neural cell adhesion molecule (NCAM), that HSG cell proliferation may be controlled via a homophilic (NCAM-NCAM) binding mechanism and that NCAM may be associated with perineural invasion by malignant salivary gland tumors.
  • Here, we investigated the effects of cimetidine on growth and perineural/neural invasion of salivary gland tumor cells.
  • METHODS: In this study, we have examined the effect of cimetidine on cancer cell adhesion to neural cells in vitro, one of the critical steps of cancer invasion and metastasis.
  • CONCLUSION: These findings suggest that growth and perineural/neural invasion of salivary gland tumors can be blocked by administration of cimetidine via induction of apoptosis and in which NCAM plays a role.
  • [MeSH-major] Cell Adhesion / drug effects. Cimetidine / pharmacology. Histamine H2 Antagonists / pharmacology. Neoplasm Invasiveness / physiopathology. Neural Cell Adhesion Molecules / metabolism. Salivary Gland Neoplasms / drug therapy. Salivary Gland Neoplasms / physiopathology

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • Hazardous Substances Data Bank. CIMETIDINE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Eur J Cancer Clin Oncol. 1988 Feb;24(2):161-7 [3356203.001]
  • [Cites] Nat Rev Cancer. 2002 Apr;2(4):301-10 [12001991.001]
  • [Cites] Science. 1988 Oct 28;242(4878):540-6 [3140380.001]
  • [Cites] J Appl Physiol (1985). 1989 Dec;67(6):2586-92 [2606866.001]
  • [Cites] Annu Rev Biochem. 1991;60:155-90 [1883195.001]
  • [Cites] J Surg Oncol. 1993 Jun;53(2):78-83 [8501910.001]
  • [Cites] Eur J Clin Invest. 1994 Jul;24(7):476-81 [7957505.001]
  • [Cites] Aust N Z J Surg. 1994 Dec;64(12):847-52 [7980260.001]
  • [Cites] Gut. 1994 Nov;35(11):1632-6 [7828988.001]
  • [Cites] J Surg Oncol. 1995 Feb;58(2):97-100 [7844990.001]
  • [Cites] Cancer Res. 1995 Sep 15;55(18):4162-7 [7545088.001]
  • [Cites] Hum Pathol. 1995 Nov;26(11):1185-90 [7590690.001]
  • [Cites] Br J Cancer. 1996 Apr;73(7):872-6 [8611398.001]
  • [Cites] Melanoma Res. 1996 Apr;6(2):95-9 [8791266.001]
  • [Cites] Otolaryngol Head Neck Surg. 1997 Nov;117(5):453-8 [9374166.001]
  • [Cites] Genes Dev. 1999 Feb 1;13(3):239-52 [9990849.001]
  • [Cites] J Biol Chem. 1999 Mar 26;274(13):9108-15 [10085161.001]
  • [Cites] Int J Cancer. 1999 May 31;81(5):835-8 [10328241.001]
  • [Cites] Trends Mol Med. 2002 Aug;8(8):385-9 [12127724.001]
  • [Cites] Hum Mol Genet. 2002 Oct 1;11(20):2371-5 [12351572.001]
  • [Cites] Nat Rev Immunol. 2002 Oct;2(10):725-34 [12360211.001]
  • [Cites] Cancer. 1981 Aug 1;48(3):745-52 [7248901.001]
  • [Cites] Ann Intern Med. 1982 Oct;97(4):573-80 [6751184.001]
  • [Cites] Am J Surg. 1986 Feb;151(2):249-55 [3484914.001]
  • [Cites] Digestion. 1999 Sep-Oct;60(5):415-21 [10473965.001]
  • [Cites] Oncol Rep. 2005 Nov;14(5):1143-9 [16211277.001]
  • [Cites] Int J Oncol. 2006 May;28(5):1021-30 [16596218.001]
  • [Cites] Oncol Rep. 2007 Mar;17(3):673-8 [17273750.001]
  • [Cites] J Biol Chem. 1999 Jan 22;274(4):2432-9 [9891013.001]
  • [Cites] Oncogene. 1999 Nov 22;18(49):6867-74 [10602462.001]
  • [Cites] Oral Oncol. 2000 Mar;36(2):248-52 [10745180.001]
  • [Cites] J Biol Chem. 2000 Jun 2;275(22):16879-84 [10828070.001]
  • [Cites] Laryngoscope. 2000 Jun;110(6):946-8 [10852510.001]
  • [Cites] Cancer Res. 2000 Jul 15;60(14):3978-84 [10919677.001]
  • [Cites] J Biol Chem. 2000 Dec 1;275(48):38095-103 [10982806.001]
  • [Cites] Lancet. 1988 Oct 29;2(8618):990-2 [2902494.001]
  • (PMID = 19091137.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Histamine H2 Antagonists; 0 / NF-kappa B; 0 / Neural Cell Adhesion Molecules; 80061L1WGD / Cimetidine
  • [Other-IDs] NLM/ PMC2635382
  •  go-up   go-down


85. Lai FY, Zhang Q, Wu QL, Qing J, Cao Y: [Expression and significance of E-cadherin in adenoid cystic carcinoma of the salivary glands]. Ai Zheng; 2007 Sep;26(9):1025-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Expression and significance of E-cadherin in adenoid cystic carcinoma of the salivary glands].
  • This study was to explore the expression of E-cadherin in adenoid cystic carcinoma of the salivary glands and its correlations to nerve invasion, regional recurrence, distant metastasis and prognosis of this disease.
  • METHODS: The expression of E-cadherin in 55 specimens of adenoid cystic carcinoma of the salivary glands and 20 specimens of normal salivary gland tissue was detected by immunohistochemistry.
  • The positive rate of E-cadherin was significantly higher in normal salivary gland tissues than in adenoid cystic carcinoma tissues (90.0% vs.63.6%, P<0.05).
  • CONCLUSION: E-cadherin expression is down-regulated in adenoid cystic carcinoma of the salivary glands, which is correlated to nerve invasion, regional recurrence and distant metastasis.
  • [MeSH-major] Cadherins / metabolism. Carcinoma, Adenoid Cystic / metabolism. Salivary Gland Neoplasms / metabolism
  • [MeSH-minor] Adult. Aged. Cranial Nerve Neoplasms / pathology. Facial Nerve Diseases / pathology. Female. Follow-Up Studies. Humans. Lung Neoplasms / secondary. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Recurrence, Local. Radiotherapy, Adjuvant. Salivary Glands / metabolism. Salivary Glands / surgery. Survival Rate


86. Neves Cde O, Soares AB, Costa AF, de Araujo VC, Furuse C, Juliano PB, Altemani A: CD10 (Neutral Endopeptidase) Expression in Myoepithelial Cells of Salivary Neoplasms. Appl Immunohistochem Mol Morphol; 2010 Mar;18(2):172-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] CD10 (Neutral Endopeptidase) Expression in Myoepithelial Cells of Salivary Neoplasms.
  • In salivary glands, expression of CD10 has only been used to identify neoplastic myoepithelial cells of pleomorphic adenomas and myoepithelial carcinomas.
  • However, its accuracy in other salivary tumors with myoepithelial component has yet to be analyzed.
  • We examined 72 salivary tumors with myoepithelial differentiation using immunohistochemical technique to detect CD10.
  • In salivary glands, CD10 expression was not detected in myoepithelial cells.
  • Surprisingly, adenoid cystic carcinomas and basal cell adenomas were negative in 100% of the cases.
  • In conclusion, salivary neoplastic myoepithelial cells gain CD10 expression in relation to their normal counterparts.
  • The high expression of CD10 by this carcinoma can be a valuable tool to separate EMEC from the tubular variant of adenoid cystic carcinomas in small incisional biopsies, where the precise diagnosis may be impossible.

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19752720.001).
  • [ISSN] 1533-4058
  • [Journal-full-title] Applied immunohistochemistry & molecular morphology : AIMM
  • [ISO-abbreviation] Appl. Immunohistochem. Mol. Morphol.
  • [Language] ENG
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / ACTA2 protein, human; 0 / Actins; 0 / Biomarkers, Tumor; EC 3.4.24.11 / Neprilysin
  •  go-up   go-down


87. Netto Jde N, Miranda AM, da Silveira HM, dos Santos TC, Pires FR: Fine-needle aspiration biopsy as an auxiliary diagnostic tool on intraoral minor salivary gland adenoid cystic carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2008 Aug;106(2):242-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fine-needle aspiration biopsy as an auxiliary diagnostic tool on intraoral minor salivary gland adenoid cystic carcinoma.
  • BACKGROUND: Fine-needle aspiration biopsy (FNAB) is useful in diagnosis of major salivary gland adenoid cystic carcinoma (ACC), but it has been rarely reported on minor salivary gland ACC.
  • OBJECTIVE: The aim of this study was to report the utility of FNAB on diagnosis of ACC involving minor salivary glands.
  • Diagnosis of the 3 cases was subsequently confirmed through histopathology.
  • CONCLUSION: The FNAB was easy to perform and cost-effective, and proved to be an useful adjunctive tool in diagnosis of intraoral ACC.
  • [MeSH-major] Biopsy, Fine-Needle / methods. Carcinoma, Adenoid Cystic / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands, Minor / pathology
  • [MeSH-minor] Adult. Cell Nucleus / ultrastructure. Cheek / pathology. Coloring Agents. Cytodiagnosis / methods. Cytoplasm / ultrastructure. Diagnosis, Differential. Extracellular Space. Female. Fluorescent Dyes. Humans. Male. Middle Aged. Mouth Mucosa / pathology. Palatal Neoplasms / pathology

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18644520.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Coloring Agents; 0 / Fluorescent Dyes
  •  go-up   go-down


88. Daa T, Yada N, Kashima K, Suzuki M, Yokoyama S: Alteration of SMAD4 does not participate in tumorigenesis of adenoid cystic carcinoma of the salivary gland. Mol Med Rep; 2009 Jan-Feb;2(1):13-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Alteration of SMAD4 does not participate in tumorigenesis of adenoid cystic carcinoma of the salivary gland.
  • SMAD4, also known as DPC4 (deleted in pancreatic carcinoma 4) was initially identified as a tumor-suppressor gene.
  • It is located on 18q21, a region frequently deleted in pancreatic carcinoma.
  • Functionally inactivating mutation of the gene also occurs in many cases of pancreatic cancer.
  • Functional loss of SMAD4 is frequently detected not only in pancreatic carcinoma but also in colorectal carcinoma.
  • The purpose of this study was to elucidate the role of SMAD4 in adenoid cystic carcinoma of the salivary glands.
  • We examined 34 cases of adenoid cystic carcinoma for loss of heterozygosity (LOH) of the SMAD4 locus and for the existence of mutations of the gene.
  • In conclusion, the infrequent LOH of the SMAD4 gene locus and lack of SMAD4 mutations indicate that SMAD4 does not play a role in the tumorigenesis of adenoid cystic carcinoma of the salivary gland.

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21475783.001).
  • [ISSN] 1791-2997
  • [Journal-full-title] Molecular medicine reports
  • [ISO-abbreviation] Mol Med Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  •  go-up   go-down


89. García de Marcos JA, Calderón-Polanco J, Poblet E, del Castillo-Pardo de Vera JL, Arroyo-Rodríguez S, Galdeano-Arenas M, Dean-Ferrer A: Primary adenoid cystic carcinoma of the mandible: case report and review of the literature. J Oral Maxillofac Surg; 2008 Dec;66(12):2609-15
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary adenoid cystic carcinoma of the mandible: case report and review of the literature.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Mandibular Neoplasms / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands, Minor / pathology
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged. Radiography, Panoramic

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19022143.001).
  • [ISSN] 1531-5053
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 30
  •  go-up   go-down


90. Zhang B, Sun CF: [The expression of tumor suppressor gene PTEN protein and focal adhesion kinase in salivary adenoid cystic carcinoma and its significance]. Shanghai Kou Qiang Yi Xue; 2005 Dec;14(6):578-81
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The expression of tumor suppressor gene PTEN protein and focal adhesion kinase in salivary adenoid cystic carcinoma and its significance].
  • PURPOSE: To investigate the expression of focal adhesion kinase(FAK) and PTEN in salivary adenoid cystic carcinoma (SACC) and its significance.
  • RESULTS: The expressions of FAK in salivary adenoid cystic carcinoma was 94%, and the negative expressions of PTEN was 70%.There was a significant difference between normal salivary gland and salivary adenoid cystic carcinoma (P<0.01).
  • [MeSH-major] Carcinoma, Adenoid Cystic / metabolism. Focal Adhesion Kinase 1 / metabolism. PTEN Phosphohydrolase / metabolism. Salivary Gland Neoplasms / metabolism
  • [MeSH-minor] Humans. Salivary Glands / metabolism

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16400482.001).
  • [ISSN] 1006-7248
  • [Journal-full-title] Shanghai kou qiang yi xue = Shanghai journal of stomatology
  • [ISO-abbreviation] Shanghai Kou Qiang Yi Xue
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] EC 2.7.10.2 / Focal Adhesion Kinase 1; EC 2.7.10.2 / PTK2 protein, human; EC 3.1.3.48 / PTEN protein, human; EC 3.1.3.67 / PTEN Phosphohydrolase
  •  go-up   go-down


91. Epivatianos A, Iordanides S, Zaraboukas T, Antoniades D: Adenoid cystic carcinoma and polymorphous low-grade adenocarcinoma of minor salivary glands: a comparative immunohistochemical study using the epithelial membrane and carcinoembryonic antibodies. Oral Dis; 2005 May;11(3):175-80
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenoid cystic carcinoma and polymorphous low-grade adenocarcinoma of minor salivary glands: a comparative immunohistochemical study using the epithelial membrane and carcinoembryonic antibodies.
  • OBJECTIVE: The purpose of this study was to investigate immunohistochemically the expression of epithelial membrane antigen (EMA) and carcinoembryonic antigen (CEA) in adenoid cystic carcinoma (AdCC) and polymorphous low-grade adenocarcinoma (PLGA) in an attempt to assess the ability of these markers to distinguish AdCC from PLGA when the histological features on routine hematoxylin and eosin are equivocal.
  • MATERIALS AND METHODS: Fourteen specimens of AdCC, 10 PLGA, and five normal minor salivary glands fixed in 10% formalin and embedded in paraffin, were retrieved from the files of our department and were retrospectively studied with the streptavidin-biotin complex method using the epithelial membrane and carcinoembryonic antibodies.
  • CONCLUSIONS: The results of this study suggest that the immunostaining of AdCC and PLGA with EMA and CEA could not offer an adjunctive aid in differential diagnosis between these two tumors.
  • [MeSH-major] Adenocarcinoma / diagnosis. Carcinoma, Adenoid Cystic / diagnosis. Salivary Gland Neoplasms / diagnosis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / analysis. Carcinoembryonic Antigen / analysis. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Mucin-1 / analysis. Retrospective Studies. Salivary Gland Diseases / diagnosis. Salivary Glands, Minor


92. Shang J, Sheng L, Wang K, Shui Y, Wei Q: Expression of neural cell adhesion molecule in salivary adenoid cystic carcinoma and its correlation with perineural invasion. Oncol Rep; 2007 Dec;18(6):1413-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Expression of neural cell adhesion molecule in salivary adenoid cystic carcinoma and its correlation with perineural invasion.
  • The expression of neural cell adhesion molecule (NCAM) was analyzed in immunohistochemical preparations from adenoid cystic carcinoma.
  • The goal was to evaluate whether NCAM expression could be used as a biological marker for the perineural invasion of adenoid cystic carcinoma in the head and neck.
  • A high incidence of perineural invasion was found in adenoid cystic carcinoma in the parotid, hard palate, maxillary sinus and oral cavity.
  • All 6 cases displayed positive NCAM staining, and 5 displayed perineural invasion in the primary adenoid cystic carcinoma.
  • In conclusion, NCAM expression can, to a certain extent, be used as a predictor of perineural invasion in adenoid cystic carcinoma.
  • [MeSH-major] Carcinoma, Adenoid Cystic / metabolism. Gene Expression Regulation, Neoplastic. Neural Cell Adhesion Molecules / metabolism. Salivary Gland Neoplasms / metabolism

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17982624.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Neural Cell Adhesion Molecules
  •  go-up   go-down


93. Hu JA, Li Y, Fang J: Effect of ERK inhibitor on pulmonary metastasis of inoculated human adenoid cystic carcinoma cells in nude mice. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Jan;109(1):117-23
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of ERK inhibitor on pulmonary metastasis of inoculated human adenoid cystic carcinoma cells in nude mice.
  • In this study, we detected the expression of phosphylated ERK1/2 in human salivary adenoid cystic carcinoma (SACC) by immunohistochemical method, the effect of various concentrations of PD98059 on the growth of ACC-M cells (a cell line of human adenoid cystic carcinoma of the salivary glands) by MTT assay, and the effect of PD98059 on the lung metastasis of inoculated ACC-M cells in nude mice.
  • The results showed that the phosphylated ERK1/2 was overexpressed in SACC, the ACC-M cell line proliferation was inhibited by PD98059, and the lung metastasis level was reduced by PD98059, indicating that ERK may be a key molecule in targeted therapy of adenoid cystic carcinoma.
  • [MeSH-major] Carcinoma, Adenoid Cystic / enzymology. Carcinoma, Adenoid Cystic / secondary. Extracellular Signal-Regulated MAP Kinases / antagonists & inhibitors. Lung Neoplasms / enzymology. Lung Neoplasms / secondary. Protein Kinase Inhibitors / pharmacology. Salivary Gland Neoplasms / pathology

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Lung Cancer.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2010 Mosby, Inc. All rights reserved.
  • (PMID = 20123382.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one; 0 / Flavonoids; 0 / Protein Kinase Inhibitors; EC 2.7.11.24 / Extracellular Signal-Regulated MAP Kinases
  •  go-up   go-down


94. Bobbio A, Copelli C, Ampollini L, Bianchi B, Carbognani P, Bettati S, Sesenna E, Rusca M: Lung metastasis resection of adenoid cystic carcinoma of salivary glands. Eur J Cardiothorac Surg; 2008 May;33(5):790-3
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lung metastasis resection of adenoid cystic carcinoma of salivary glands.
  • BACKGROUND: Adenoid cystic carcinoma is a rare tumour originating from the exocrine mucous glands, known for its high propensity for distant metastases.
  • The value of lung metastasis resection from adenoid cystic carcinoma of salivary glands origin is evaluated.
  • METHODS: A retrospective study was conducted on patients undergoing surgery for primary adenoid cystic carcinoma of the salivary glands between 1982 and 2006.
  • RESULTS: Twenty-six men and 24 women with a median age of 57 years (range 33-79) underwent radical surgery for adenoid cystic carcinoma during the study period.
  • CONCLUSIONS: Patients with adenoid cystic carcinoma could be frequently encountered with disease recurrence confined to the lung.
  • [MeSH-major] Lung Neoplasms / secondary. Lung Neoplasms / surgery. Neoplasm Recurrence, Local / surgery. Salivary Gland Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Carcinoma, Adenoid Cystic / mortality. Carcinoma, Adenoid Cystic / secondary. Carcinoma, Adenoid Cystic / surgery. Disease-Free Survival. Female. Follow-Up Studies. Humans. Kaplan-Meier Estimate. Linear Models. Male. Middle Aged. Retrospective Studies. Survival Rate

  • Genetic Alliance. consumer health - Adenoid Cystic Carcinoma.
  • MedlinePlus Health Information. consumer health - Lung Cancer.
  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18343149.001).
  • [ISSN] 1010-7940
  • [Journal-full-title] European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • [ISO-abbreviation] Eur J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


95. Luna MA: Sinonasal tubulopapillary low-grade adenocarcinoma: a specific diagnosis or just another seromucous adenocarcinoma? Adv Anat Pathol; 2005 May;12(3):109-15
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sinonasal tubulopapillary low-grade adenocarcinoma: a specific diagnosis or just another seromucous adenocarcinoma?
  • Histopathologically, sinonasal adenocarcinomas fall into four categories: the intestinal type, the conventional salivary gland type (eg, adenoid cystic carcinoma, acinic cell carcinoma), the seromucous type, and the low-grade not otherwise specified type.
  • Recently, a new type of sinonasal adenocarcinoma has been described, called tubulopapillary low-grade adenocarcinoma.
  • In this commentary, the histologic features of this type of tumor are compared with those of the other types of sinonasal adenocarcinoma.
  • The clinicopathologic characteristics and probable origin of this type of adenocarcinoma are also discussed.
  • [MeSH-major] Adenocarcinoma / pathology. Adenocarcinoma, Papillary / pathology. Paranasal Sinus Neoplasms / pathology

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentOn] Virchows Arch. 2003 Aug;443(2):152-8 [12827515.001]
  • (PMID = 15900111.001).
  • [ISSN] 1072-4109
  • [Journal-full-title] Advances in anatomic pathology
  • [ISO-abbreviation] Adv Anat Pathol
  • [Language] eng
  • [Publication-type] Comment; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


96. Kupferman ME, de la Garza GO, Santillan AA, Williams MD, Varghese BT, Huh W, Roberts D, Weber RS: Outcomes of pediatric patients with malignancies of the major salivary glands. Ann Surg Oncol; 2010 Dec;17(12):3301-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Outcomes of pediatric patients with malignancies of the major salivary glands.
  • BACKGROUND: To report the outcomes and early to long term treatment complications among pediatric patients with major salivary gland malignancies treated at a single institution.
  • MATERIALS AND METHOD: This study was a retrospective case review set at a tertiary referral cancer center.
  • Patients less than 19 years of age with a diagnosis of a major salivary gland malignancy were identified at the M. D.
  • The majority of tumors arose in the parotid gland (83%), and the most common pathology was mucoepidermoid carcinoma (46%).
  • Lymphatic metastasis was identified in 37% of patients, nearly all with mucoepidermoid carcinoma.
  • CONCLUSIONS: Survival of pediatric patients with major salivary gland carcinomas is favorable.
  • [MeSH-major] Adenocarcinoma / therapy. Carcinoma, Adenoid Cystic / therapy. Carcinoma, Mucoepidermoid / therapy. Carcinoma, Squamous Cell / therapy. Salivary Gland Neoplasms / therapy

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20585877.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA016672
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


97. González-García R, Nam-Cha SH, Muñoz-Guerra MF, Gamallo-Amat C: Basal cell adenoma of the parotid gland. Case report and review of the literature. Med Oral Patol Oral Cir Bucal; 2006 Mar;11(2):E206-9
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Basal cell adenoma of the parotid gland. Case report and review of the literature.
  • Basal cell adenoma of the salivary glands is an uncommon type of monomorphous adenoma.
  • Its most frequent location is the parotid gland.
  • Due to prognostic implications, differential diagnosis with basal cell adenocarcinoma, adenoid cystic carcinoma and basaloid squamous cell carcinoma is mandatory.
  • We describe a case of basal cell adenoma of the parotid gland.
  • We also review the literature and discuss the diagnosis and management of this rare entity.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16505803.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng; spa
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 21
  •  go-up   go-down


98. Moore BA, Burkey BB, Netterville JL, Butcher RB 2nd, Amedee RG: Surgical management of minor salivary gland neoplasms of the palate. Ochsner J; 2008;8(4):172-80
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical management of minor salivary gland neoplasms of the palate.
  • OBJECTIVE: Minor salivary gland tumors are uncommon, accounting for up to 15% of salivary gland neoplasms.
  • We describe our experience with both benign and malignant tumors of the palatal minor salivary glands, focusing on the extent of resection and options for defect reconstruction.
  • RESULTS: From 1994 to 2002, 37 patients with primary neoplasms originating in the palatal minor salivary glands were treated at a single institution.
  • The most common malignant tumor encountered was low grade polymorphous adenocarcinoma, followed by mucoepidermoid carcinoma, and adenoid cystic carcinoma.
  • CONCLUSIONS: Neoplasms of the minor salivary glands in the palate may be excised, with limits dictated by tumor histopathology and perineural invasion.

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Dentomaxillofac Radiol. 1997 Jan;26(1):16-21 [9446985.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 1995 Jun;121(6):607-12 [7772309.001]
  • [Cites] Head Neck. 1998 Dec;20(8):699-706 [9790291.001]
  • [Cites] Arch Otolaryngol. 1978 Sep;104(9):501-4 [210749.001]
  • [Cites] Ear Nose Throat J. 1989 Feb;68(2):137-40 [2656236.001]
  • [Cites] Am J Otolaryngol. 1989 Jul-Aug;10(4):250-6 [2764237.001]
  • [Cites] Laryngoscope. 1987 Nov;97(11):1343-5 [2823035.001]
  • [Cites] Oral Surg Oral Med Oral Pathol. 1988 Sep;66(3):323-33 [2845326.001]
  • [Cites] Laryngoscope. 1980 Apr;90(4):576-84 [6767146.001]
  • [Cites] Laryngoscope. 1995 Nov;105(11):1155-60 [7475867.001]
  • [Cites] J Oral Maxillofac Surg. 1994 May;52(5):454-9 [8169706.001]
  • [Cites] J Laryngol Otol. 1993 Sep;107(9):858-61 [8228611.001]
  • [Cites] Otolaryngol Head Neck Surg. 1993 Mar;108(3):304-5 [8385307.001]
  • [Cites] J Okla Dent Assoc. 1996 Spring;86(4):50-2 [9540689.001]
  • [Cites] Histopathology. 1998 Jun;32(6):521-9 [9675591.001]
  • [Cites] Otolaryngol Clin North Am. 1999 Oct;32(5):875-86 [10477793.001]
  • [Cites] Otolaryngol Head Neck Surg. 1999 Nov;121(5):548-52 [10547468.001]
  • [Cites] Am J Surg Pathol. 2000 Oct;24(10):1319-28 [11023093.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 2001 Jul;127(7):837-41 [11448360.001]
  • [Cites] Laryngoscope. 2003 Jun;113(6):946-51 [12782803.001]
  • [Cites] Am J Surg. 1991 Oct;162(4):330-6 [1659242.001]
  • [Cites] Cancer. 1984 Feb 15;53(4):935-42 [6692293.001]
  • [Cites] Acta Cytol. 1998 Jul-Aug;42(4):888-98 [9684573.001]
  • (PMID = 21603498.001).
  • [ISSN] 1524-5012
  • [Journal-full-title] The Ochsner journal
  • [ISO-abbreviation] Ochsner J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3096363
  • [Keywords] NOTNLM ; Palate / salivary gland neoplasms
  •  go-up   go-down


99. Conti C, Ferraris P, Garavaglia M, Giorgini E, Rubini C, Sabbatini S, Tosi G: Microimaging FTIR of head and neck tumors. IV. Microsc Res Tech; 2009 Feb;72(2):67-75
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • On continuing our studies on head and neck neoplasia, specimens from salivary gland tumors have been explored by using infrared microimaging spectroscopy to discern healthy from neoplastic tissues.
  • Samples with Warthin tumor, epithelial displasia, marginal B-cell lymphoma, low-grade adenocarcinoma, and adenoid cystic carcinoma pathologies have been investigated by using conventional light sources.
  • [MeSH-major] Image Processing, Computer-Assisted / methods. Pattern Recognition, Automated / methods. Salivary Gland Neoplasms / pathology. Spectroscopy, Fourier Transform Infrared / methods
  • [MeSH-minor] Biomarkers, Tumor / analysis. Cluster Analysis. Humans. Normal Distribution. Principal Component Analysis. Salivary Glands / chemistry. Salivary Glands / pathology

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2008 Wiley-Liss, Inc.
  • (PMID = 18825780.001).
  • [ISSN] 1097-0029
  • [Journal-full-title] Microscopy research and technique
  • [ISO-abbreviation] Microsc. Res. Tech.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down


100. Moatemri R, Belajouza H, Farroukh U, Ommezzine M, Slama A, Ayachi S, Khochtali H, Bakir A: [Epidemiological profile of salivary-glands tumors in a Tunisian teaching hospital]. Rev Stomatol Chir Maxillofac; 2008 Jun;109(3):148-52
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Epidemiological profile of salivary-glands tumors in a Tunisian teaching hospital].
  • INTRODUCTION: Salivary-glands tumors come in various presentations and the epidemiological data are variable.
  • The aim of this retrospective study was to establish an epidemiological profile of salivary-glands tumors in a Tunisian teaching hospital and to compare it to published data.
  • Sixty percent of the tumors were parotid lesions, 16% were submandibular and 24% located on minor salivary glands.
  • Most minor salivary-glands tumors were located on the palate.
  • DISCUSSION: Benign salivary-glands tumors, often have a parotid localization affect, more women in the Tunisian population.
  • [MeSH-major] Salivary Gland Neoplasms / epidemiology
  • [MeSH-minor] Adenoma, Pleomorphic / epidemiology. Adolescent. Adult. Age Factors. Aged. Aged, 80 and over. Carcinoma, Adenoid Cystic / epidemiology. Carcinoma, Mucoepidermoid / epidemiology. Child. Child, Preschool. Epidemiologic Studies. Female. Hospitals, Teaching / statistics & numerical data. Humans. Infant. Male. Middle Aged. Parotid Neoplasms / epidemiology. Retrospective Studies. Salivary Glands, Minor / pathology. Sex Factors. Submandibular Gland Neoplasms / epidemiology. Tunisia / epidemiology

  • MedlinePlus Health Information. consumer health - Salivary Gland Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18538362.001).
  • [ISSN] 0035-1768
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] France
  •  go-up   go-down






Advertisement