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11. Komatsubara H, Umeda M, Ojima Y, Minamikawa T, Komori T: Detection of cancer cells in the peripheral blood and lung of mice after transplantation of human adenoid cystic carcinoma. Kobe J Med Sci; 2005;51(5-6):67-72
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  • [Title] Detection of cancer cells in the peripheral blood and lung of mice after transplantation of human adenoid cystic carcinoma.
  • We attempted to detect cancer cells from the lung and peripheral blood in nude mice, into which a human adenoid cystic carcinoma (ACC) line (KOA-1 and KOA-1L3) had been transplanted.
  • Positive PCR reaction was observed in the lung of a total of 19 of 47 (40.4%) mice into which KOA-1 tumor cells had been transplanted: none of 10 after 1 month, seven of 18 after 2 months, and 12 of 19 after 3 months or later.
  • The KOA-1L3 tumor showed earlier lung metastasis, that is, two of 24 after 7 days and two of 12 after 14 days.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Lung Neoplasms / secondary. Neoplastic Cells, Circulating / pathology


12. Fatimi SH, Sajwani RA, Rizvi N, Javed MA, Khan A, Ahmad U: Chamberlain mediastinotomy for diagnosis of adenoid cystic carcinoma of trachea. Heart Lung Circ; 2008 Dec;17(6):515-6
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  • [Title] Chamberlain mediastinotomy for diagnosis of adenoid cystic carcinoma of trachea.
  • Primary tracheal tumours are extremely rare.
  • The lesion was biopsied through a chamberlain mediastinotomy, under local and mask anaesthesia and was found to be primary adenoid cystic carcinoma.
  • [MeSH-major] Carcinoma, Adenoid Cystic / complications. Mediastinoscopy / methods. Tracheal Neoplasms / complications. Tracheal Stenosis / etiology

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  • (PMID = 17931975.001).
  • [ISSN] 1444-2892
  • [Journal-full-title] Heart, lung & circulation
  • [ISO-abbreviation] Heart Lung Circ
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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13. Trepp R, Padberg BC, Varga Z, Cathomas R, Inauen R, Reinhart WH: Extensive extranodal metastases of basal-like breast cancer with predominant myoepithelial spindle cell differentiation. Pathol Res Pract; 2010 May 15;206(5):334-7
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  • These include multifocal myoepitheliomatosis, the rare mixed tumor or pleomorphic adenoma, adenoid cystic carcinoma, adenomyoepithelioma and myoepithelial carcinoma (malignant myoepithelioma).
  • Myoepithelial carcinoma is the only lesion purely composed of myoepithelial cells.
  • The presented case of a breast carcinoma with dominant myoepithelial/spindle cell differentiation in a 58-year-old woman is an excellent example to document the highly aggressive biological behavior of this tumor phenotype.
  • [MeSH-major] Breast Neoplasms / pathology. Carcinoma / secondary. Kidney Neoplasms / secondary. Liver Neoplasms / secondary. Lung Neoplasms / secondary. Skin Neoplasms / secondary


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4. Banki F, Khalil K, Kott MM, Cota AL: Adenoid cystic carcinoma of the thymus gland: a rare tumor. Ann Thorac Surg; 2010 Oct;90(4):e56-8
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  • [Title] Adenoid cystic carcinoma of the thymus gland: a rare tumor.
  • We present a case of adenoid cystic carcinoma of thymus in a 65-year-old woman that was initially misdiagnosed and was treated as non-small cell carcinoma of the lung.
  • [MeSH-major] Carcinoma, Adenoid Cystic / diagnosis. Thymus Neoplasms / diagnosis

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  • [Copyright] Copyright © 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20868782.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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15. Hu K, Gan YH, Li SL, Gao Y, Wu DC, Wang CY, Yu GY: Relationship of activated extracellular signal-regulated kinase 1/2 with lung metastasis in salivary adenoid cystic carcinoma. Oncol Rep; 2009 Jan;21(1):137-43
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  • [Title] Relationship of activated extracellular signal-regulated kinase 1/2 with lung metastasis in salivary adenoid cystic carcinoma.
  • Lung metastasis is one of the important characteristics of salivary adenoid cystic carcinoma (SACC).
  • Although activation of extracellular signal-regulated kinase 1/2 (ERK1/2) pathway may be associated with cancer progression in some malignant tumors, its roles in lung metastasis of SACC remains unclear.
  • We examined the expression of activated ERK1/2 in SACC-LM with high lung-metastatic rate and SACC-83 with low lung-metastatic rate, as well as in the tissues from lung-metastatic and non-metastatic groups of SACC patients.
  • Similarly, immunohistochemistry showed that expression of activated ERK1/2 was detected in 73% (8/11) of the primary tissues from SACC patients with lung metastasis, while only 25% (3/12) of the primary tissues from SACC patients without lung metastasis (P<0.05).
  • The present findings suggested that the elevated expression of activated ERK1/2 may play a role in lung metastasis of salivary adenoid cystic carcinoma.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Lung Neoplasms / secondary. Mitogen-Activated Protein Kinase 1 / metabolism. Mitogen-Activated Protein Kinase 3 / metabolism. Salivary Gland Neoplasms / pathology


16. Campistron M, Rouquette I, Courbon F, Chabbert V, Rochaix P, Prévot G, Laroumagne S, Têtu L, Didier A, Mazières J: Adenoid cystic carcinoma of the lung: interest of 18FDG PET/CT in the management of an atypical presentation. Lung Cancer; 2008 Jan;59(1):133-6
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  • [Title] Adenoid cystic carcinoma of the lung: interest of 18FDG PET/CT in the management of an atypical presentation.
  • Adenoid cystic carcinoma (ACC) is a common head and neck tumor originating from salivary glands but that can also exceptionally develop in the trachea and major bronchi.
  • We here report for the first time a case of lung ACC with a synchronous liver metastasis proved by biopsy.
  • Moreover, we report the interest of performing a 18FDG PET-CT as both primary tumor and liver metastasis presented an intense FDG uptake.
  • We propose that 18FDG PET-CT should be considered in the initial staging of lung ACC in selected patients.
  • [MeSH-major] Carcinoma, Adenoid Cystic / radionuclide imaging. Fluorodeoxyglucose F18. Lung Neoplasms / radionuclide imaging

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  • (PMID = 17640764.001).
  • [ISSN] 0169-5002
  • [Journal-full-title] Lung cancer (Amsterdam, Netherlands)
  • [ISO-abbreviation] Lung Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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17. Yu T, Gao QH, Wang XY, Wen YM, Li LJ: Malignant sublingual gland tumors: a retrospective clinicopathologic study of 28 cases. Oncology; 2007;72(1-2):39-44
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  • Eighteen cases (64.3%) were adenoid cystic carcinoma; 16 (57.1%) cases were clinically staged as III-IV.
  • Adenoid cystic carcinoma was mainly of the histologic type, and the other histologic classifications included mucoepidermoid carcinoma, myoepithelial carcinoma, polymorphous low-grade adenocarcinoma, adenocarcinoma and malignant pleomorphic adenoma.
  • Pulmonary metastasis and tumor recurrence were the main death reasons.
  • CONCLUSIONS: Malignant sublingual gland tumors are extremely rare and most are adenoid cystic carcinoma.
  • For adenoid cystic carcinoma, hematogenous spread is common, and pulmonary metastasis is a common pathway of the distant metastasis.
  • For some patients having lung metastasis, regional control is also important as there are some examples of patients surviving many years with asymptomatic pulmonary metastases.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Sublingual Gland Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Cause of Death. Female. Humans. Lung Neoplasms / mortality. Lung Neoplasms / secondary. Male. Middle Aged. Neoplasm Recurrence, Local / mortality. Prognosis. Retrospective Studies

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  • [Copyright] Copyright 2007 S. Karger AG, Basel.
  • (PMID = 17998789.001).
  • [ISSN] 1423-0232
  • [Journal-full-title] Oncology
  • [ISO-abbreviation] Oncology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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18. Ettl T, Schwarz S, Kühnel T, Stockmann P, Reichert TE, Driemel O: [Prognostic value of immunohistochemistry in salivary gland cancer]. HNO; 2008 Feb;56(2):231-8
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  • RESULTS: Findings included the following: an association between loss of maspin and the presence of nodal metastasis, residual tumour, and poor overall survival for adenoid cystic carcinoma; common C-KIT expression in adenoid cystic carcinoma (92%); correlation of loss of C-KIT with high malignancy grade, nodal metastases, high proliferative activity (Ki-67>30%), and unfavourable survival in all tumours; common HER2 expression (83%) in salivary duct carcinoma but no relation to the total collective's survival.
  • [MeSH-major] Biomarkers, Tumor / analysis. Neoplasm Proteins / analysis. Risk Assessment / methods. Salivary Gland Neoplasms / diagnosis. Salivary Gland Neoplasms / mortality


19. Schwentner I, Obrist P, Thumfart W, Sprinzl G: Distant metastasis of parotid gland tumors. Acta Otolaryngol; 2006 Apr;126(4):340-5
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  • The likelihood of developing distant metastasis is associated with high-grade tumors, such as adenoid cystic carcinoma, salivary duct carcinoma, high-grade mucoepidermoid carcinoma and tumors located in the submandibular gland, posterior tongue and pharyngeal tumors.
  • [MeSH-minor] Aged. Bone Neoplasms / secondary. Brain Neoplasms / secondary. Carcinoma, Acinar Cell / pathology. Carcinoma, Acinar Cell / secondary. Carcinoma, Adenoid Cystic / pathology. Carcinoma, Adenoid Cystic / secondary. Carcinoma, Mucoepidermoid / pathology. Carcinoma, Mucoepidermoid / secondary. Fatal Outcome. Humans. Immunohistochemistry. Incidence. Liver Neoplasms / secondary. Lung Neoplasms / secondary. Magnetic Resonance Imaging. Male. Parotid Gland / pathology. Parotid Gland / surgery. Salivary Ducts / pathology. Tomography, X-Ray Computed

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  • (PMID = 16608783.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Norway
  • [Number-of-references] 32
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20. Zushi Y, Noguchi K, Hashitani S, Sakurai K, Segawa E, Takaoka K, Toyohara Y, Tanaka N, Kishimoto H, Urade M: Relations among expression of CXCR4, histological patterns, and metastatic potential in adenoid cystic carcinoma of the head and neck. Int J Oncol; 2008 Dec;33(6):1133-9
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  • [Title] Relations among expression of CXCR4, histological patterns, and metastatic potential in adenoid cystic carcinoma of the head and neck.
  • Adenoid cystic carcinoma (ACC) may acquire a chemokine-mediated mechanism during the process of metastasis.
  • Our results showed that patients whose tumors expressed high levels of CXCR4 had metastases to the regional lymph nodes and the lung, resulting in poor outcomes.
  • The histological pattern of ACCI, associated with spontaneous metastasis to the neck, changed from cribriform to undifferentiated carcinoma and was highly metastatic to the lung.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Carcinoma, Adenoid Cystic / immunology. Head and Neck Neoplasms / immunology. Lung Neoplasms / immunology. Receptors, CXCR4 / metabolism

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  • (PMID = 19020745.001).
  • [ISSN] 1019-6439
  • [Journal-full-title] International journal of oncology
  • [ISO-abbreviation] Int. J. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CXCR4 protein, human; 0 / RNA, Messenger; 0 / Receptors, CXCR4
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21. Pedro Silva IE, Osorio Acosta V, Farfán Chávez FA: [Cystic adenoid carcinoma of the prostate. Report of two cases]. Arch Esp Urol; 2006 Oct;59(8):823-5
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  • [Title] [Cystic adenoid carcinoma of the prostate. Report of two cases].
  • [Transliterated title] Carcinoma adenoideo quístico de la próstata. Presentación de 2 casos.
  • OBJECTIVE: We report two cases with the pathologic diagnosis of cystic adenoid carcinoma of the prostate, an extremely rare tumor.
  • METHODS: We evaluate two patients with different age, clinical presentation, diagnosis, treatment and outcome.
  • The first patient underwent radical prostatectomy and adjuvant immunotherapy; six years after surgery he developed lung metastasis and died.
  • CONCLUSIONS: The clinical presentation is non specific, with the diagnosis generally obtained by transurethral resection or transrectal biopsy after the suspicion of an abnormal digital rectal examination or ultrasound.
  • [MeSH-major] Carcinoma, Adenoid Cystic / diagnosis. Prostatic Neoplasms / diagnosis


22. Zang G, Miao L, Mu Y, Qiao C, Liu J, Ke X, Zheng C, Sun H: Adenoviral mediated transduction of adenoid cystic carcinoma by human TRAIL gene driven with hTERT tumor specific promoter induces apoptosis. Cancer Biol Ther; 2009 May;8(10):966-72
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  • [Title] Adenoviral mediated transduction of adenoid cystic carcinoma by human TRAIL gene driven with hTERT tumor specific promoter induces apoptosis.
  • Adenoid cystic carcinoma (ACC) is a common malignant tumor in salivary glands.
  • Transduction of SACC-83, but not of control human embryo-fibrocyte lung (HEL) cells, led to apoptosis as measured by MTT assay and flow cytomerty.
  • [MeSH-major] Apoptosis / genetics. Carcinoma, Adenoid Cystic / therapy. Salivary Gland Neoplasms / therapy. TNF-Related Apoptosis-Inducing Ligand / genetics. Telomerase / genetics

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  • (PMID = 19587531.001).
  • [ISSN] 1555-8576
  • [Journal-full-title] Cancer biology & therapy
  • [ISO-abbreviation] Cancer Biol. Ther.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Formazans; 0 / TNF-Related Apoptosis-Inducing Ligand; 0 / Tetrazolium Salts; 23305-68-2 / MTT formazan; EC 2.7.7.49 / TERT protein, human; EC 2.7.7.49 / Telomerase
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23. Triantafillidou K, Dimitrakopoulos J, Iordanidis F, Koufogiannis D: Management of adenoid cystic carcinoma of minor salivary glands. J Oral Maxillofac Surg; 2006 Jul;64(7):1114-20
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  • [Title] Management of adenoid cystic carcinoma of minor salivary glands.
  • PURPOSE: Adenoid cystic carcinoma (ACC) is a rare malignant tumor originating from the salivary glands.
  • The distribution of the primary sites was buccal mucosa (3), floor of the mouth (1), hard palate (3), soft palate (2), junction of hard and soft palate (7), and hard or soft palate with spread in the paranasal sinus etc (6).
  • Distant metastases (lung) occurred in 2 patients, 2 years and 6 years after completing the treatment.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Carcinoma, Adenoid Cystic / surgery. Ki-67 Antigen / metabolism. Salivary Gland Neoplasms / surgery

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  • (PMID = 16781345.001).
  • [ISSN] 0278-2391
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen
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24. Masuya D, Haba R, Huang CL, Yokomise H: Myoepithelial carcinoma of the lung. Eur J Cardiothorac Surg; 2005 Nov;28(5):775-7
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  • [Title] Myoepithelial carcinoma of the lung.
  • Primary lung carcinomas showing features of salivary gland-type neoplasms are rare.
  • Many are mucoepidermoid carcinomas and adenoid cystic carcinomas.
  • Myoepithelial carcinoma of the lung is extremely rare, and in the WHO classification is classified as 'Others' among carcinomas of the salivary gland.
  • Here we report a resected case of myoepithelial carcinoma of the lung, including details of clinical examination, with a review of previously documented cases.
  • [MeSH-major] Lung Neoplasms / ultrastructure. Myoepithelioma / ultrastructure

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  • (PMID = 16188445.001).
  • [ISSN] 1010-7940
  • [Journal-full-title] European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • [ISO-abbreviation] Eur J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 5
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25. Haresh KP, Prabhakar R, Rath GK, Sharma DN, Julka PK, Subramani V: Adenoid cystic carcinoma of the trachea treated with PET-CT based intensity modulated radiotherapy. J Thorac Oncol; 2008 Jul;3(7):793-5
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  • [Title] Adenoid cystic carcinoma of the trachea treated with PET-CT based intensity modulated radiotherapy.
  • Primary tumors of the trachea are rare and are usually malignant in adults and benign in children.
  • Adenoid cystic carcinoma, which is of salivary gland origin, account for about one thirds of adult primary tracheal tumors.
  • Computed tomography scan of the thorax at our hospital showed a residual disease in the primary site, size of which was same as that in the preoperative scan.
  • Because there was a compromised respiratory reserve due to pneumonectomy we decided to keep the radiation dose to the remaining lung as low as possible.
  • Presently he is disease free with good pulmonary reserve.
  • [MeSH-major] Carcinoma, Adenoid Cystic / radiotherapy. Positron-Emission Tomography. Radiotherapy, Intensity-Modulated. Tomography, X-Ray Computed. Tracheal Neoplasms / radiotherapy

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  • (PMID = 18594327.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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26. Yurut-Caloglu V, Caloglu M, Ozyilmaz F, Saynak M, Cosar-Alas R, Karagol H, Bayir-Angin G, Uzal C: Lung, bone, skeletal muscles and cutaneous metastases from adenoid cystic carcinoma of the parotid gland: a case report and review of the literature. Med Oncol; 2007;24(4):458-62
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  • [Title] Lung, bone, skeletal muscles and cutaneous metastases from adenoid cystic carcinoma of the parotid gland: a case report and review of the literature.
  • Adenoid cystic carcinoma is the second most common malignancy of the major and minor salivary glands after mucoepidemoid carcinoma.
  • Skeletal muscle and cutaneous metastases from adenoid cystic carcinoma of the parotid gland are extremely rare.
  • In this case, a 40-year-old man with lung and bone metastases followed by skeletal muscle and cutaneous metastases from adenoid cystic carcinoma of the right parotid gland is presented.
  • [MeSH-major] Bone Neoplasms / diagnosis. Carcinoma, Adenoid Cystic / diagnosis. Lung Neoplasms / diagnosis. Muscle Neoplasms / diagnosis. Parotid Neoplasms / pathology. Skin Neoplasms / diagnosis

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  • (PMID = 17917100.001).
  • [ISSN] 1357-0560
  • [Journal-full-title] Medical oncology (Northwood, London, England)
  • [ISO-abbreviation] Med. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 26
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27. Wang Y, Feng GS, Tian H, Zhang ZH, Xiong T: [Fluorescent imaging of angiogenesis and spontaneous metastasis in transplanted hepatoma: experiment with mice]. Zhonghua Yi Xue Za Zhi; 2007 Dec 11;87(46):3307-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To establish stable enhanced green fluorescent protein (GFP) -expressing human adenoid cystic carcinoma (ACC-M-GFP) cell lines with high lung metastatic potential, and to study the value and influential factor of in vivo monitoring of metastasis and angiogenesis by fluorescent imaging.
  • METHODS: Human adenoid cystic carcinoma cell line ACC-M-GFP labeled with enhanced GFP was established.
  • Metastasis of lung and lymph node was found by single organ imaging after 16 -18 weeks.
  • [MeSH-major] Liver Neoplasms / pathology. Liver Neoplasms, Experimental / pathology. Lung Neoplasms / secondary. Neovascularization, Pathologic / pathology
  • [MeSH-minor] Animals. Carcinoma, Adenoid Cystic / genetics. Carcinoma, Adenoid Cystic / metabolism. Carcinoma, Adenoid Cystic / pathology. Cell Line, Tumor. Green Fluorescent Proteins / genetics. Green Fluorescent Proteins / metabolism. Humans. Mice. Mice, Inbred BALB C. Mice, Nude. Microscopy, Fluorescence. Transplantation, Heterologous

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  • (PMID = 18396632.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 147336-22-9 / Green Fluorescent Proteins
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28. Li L, Luo W, Gan X, Su L, Zeng W: [Adenoid cystic carcinoma of ENT associated with hard lump: a report of 9 cases]. Lin Chuang Er Bi Yan Hou Ke Za Zhi; 2006 Oct;20(19):875-7
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  • [Title] [Adenoid cystic carcinoma of ENT associated with hard lump: a report of 9 cases].
  • OBJECTIVE: To assess the clinical and pathological features of the patients with ENT adenoid cystic carcinoma (ENTACC) who presented with hard lump, and to detect its prognosis.
  • RESULT: The period from the occurrence of primary symptoms to definite diagnosis was 4 years and 3 months on average.
  • Five patients died, among which 3 died with lung metastases, 2 with local lymphatic metastases, 1 with bone metastases and 1 with encephalic diffusion.
  • CONCLUSION: The pathological result of these 9 cases were all salivary gland derived adenoid cystic carcinoma of solid type.
  • [MeSH-major] Carcinoma, Adenoid Cystic. Salivary Gland Neoplasms

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  • (PMID = 17168112.001).
  • [Journal-full-title] Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology
  • [ISO-abbreviation] Lin Chuang Er Bi Yan Hou Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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29. Mao N, Zuo C, Gan N, Zhu J, Huang D, Liu D, Xie T, Pan H, Huang Y: [Trachea-bronchoplasty in the treatment of centrally located lung cancer]. Zhongguo Fei Ai Za Zhi; 2005 Aug 20;8(4):329-31
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  • [Title] [Trachea-bronchoplasty in the treatment of centrally located lung cancer].
  • BACKGROUND: To maximize the preservation of functional pulmonary parenchyma and improve the quality of life of patients with centrally located lung cancer, trachea-bronchoplasty has been used in clinical application with good efficacy.
  • The aim of this study is to explore the appropriate admission and management of trachea-bronchoplasty and prevent complications of trachea-bronchial sleeve resection in the treatment of centrally located lung cancer.
  • METHODS: Seventy-six patients with central lung cancer, who were treated with trachea-bronchoplasty from June, 1988 to October, 2004, were analyzed.
  • There were 49 cases of squamous cell carcinoma, 16 adenocarcinoma, 7 adenosquamous carcinoma, 3 small cell lung cancer and 1 adenoid cystic adenocarcinoma.
  • CONCLUSIONS: The trachea-bronchoplasty can not only preserve functional pulmonary parenchyma as much as possible and improve the quality of life of patients, but also provide an operative opportunity to those patients with poor pulmonary function in the treatment of centrally located lung cancer.

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  • (PMID = 21108894.001).
  • [ISSN] 1009-3419
  • [Journal-full-title] Zhongguo fei ai za zhi = Chinese journal of lung cancer
  • [ISO-abbreviation] Zhongguo Fei Ai Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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30. Chen SW, Huang HZ, Liu XQ: [Dynamic observation of lung metastasis model of adenoid cystic carcinoma]. Zhonghua Kou Qiang Yi Xue Za Zhi; 2005 Sep;40(5):383-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Dynamic observation of lung metastasis model of adenoid cystic carcinoma].
  • OBJECTIVE: To form ACC-M-GFP cells by transfecting pEGFP-1 into ACC-M cells, and to build up lung metastasis model of adenoid cystic carcinoma for dynamic observation in simulated lung environment.
  • The simulated lung environment was built up, and dynamic observation was performed by laser confocal microscopy within four weeks after transfection.
  • CONCLUSIONS: We successfully built up a lung metastasis model of adenoid cystic carcinoma for dynamic observation.
  • [MeSH-major] Carcinoma, Adenoid Cystic / secondary. Green Fluorescent Proteins / genetics. Lung Neoplasms / secondary. Mouth Neoplasms / pathology. Neoplasms, Experimental

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  • (PMID = 16255921.001).
  • [ISSN] 1002-0098
  • [Journal-full-title] Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
  • [ISO-abbreviation] Zhonghua Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / enhanced green fluorescent protein; 147336-22-9 / Green Fluorescent Proteins
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31. Yang Y, Jiang M, Cao D, Gou H: [Clinical analysis of 8 cases of tracheal adenoid cystic carcinoma]. Zhongguo Fei Ai Za Zhi; 2007 Jun 20;10(3):237-9
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  • [Title] [Clinical analysis of 8 cases of tracheal adenoid cystic carcinoma].
  • BACKGROUND: Tracheal adenoid cystic carcinoma (TACC) is a rare, low malignant and primary tracheal carcinoma, which is easily misdiagnosed and missedly diagnosed.
  • Fiberoptic bronchoscope and computerized tomography were reliable examinations for final diagnosis.

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  • (PMID = 21118655.001).
  • [ISSN] 1009-3419
  • [Journal-full-title] Zhongguo fei ai za zhi = Chinese journal of lung cancer
  • [ISO-abbreviation] Zhongguo Fei Ai Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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32. Ahn Y, Chang H, Lim YS, Hah JH, Kwon TK, Sung MW, Kim KH: Primary tracheal tumors: review of 37 cases. J Thorac Oncol; 2009 May;4(5):635-8
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  • [Title] Primary tracheal tumors: review of 37 cases.
  • INTRODUCTION: Primary tracheal tumors are rare, and composed of various benign and malignant pathologies.
  • The aims of this study were to establish the clinical manifestations and treatment outcomes of primary tracheal tumors and explore the prognostic variables for malignant tracheal tumors.
  • Squamous cell carcinomas (n = 11) and adenoid cystic carcinomas (n = 9) comprised most of the malignant tumors.
  • Five-year overall survival rate was 41.1% for squamous cell carcinoma and 45.7% for adenoid cystic carcinoma and no statistically significant difference (p = 0.673) was observed.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Carcinoma, Squamous Cell / pathology. Papilloma / pathology. Tracheal Neoplasms / pathology

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  • (PMID = 19357541.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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33. Chu WF, Wu DM, Liu W, Wu LJ, Li DZ, Xu DY, Wang XF: Sulforaphane induces G2-M arrest and apoptosis in high metastasis cell line of salivary gland adenoid cystic carcinoma. Oral Oncol; 2009 Nov;45(11):998-1004
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  • [Title] Sulforaphane induces G2-M arrest and apoptosis in high metastasis cell line of salivary gland adenoid cystic carcinoma.
  • New chemotherapeutic strategy should be investigated to enhance clinical management in salivary gland adenoid cystic carcinoma (ACC).
  • Cell survives, apoptosis, cell cycle progression and molecular targets were identified by multiple detecting techniques, including trypan blue dye exclusion assay, electron microscopy, AO/EB staining, flow cytometry and immunoblotting in human lung high metastasis cell line of salivary gland adenoid cystic carcinoma (ACC-M).
  • [MeSH-major] Anticarcinogenic Agents / pharmacology. Carcinoma, Adenoid Cystic / drug therapy. Lung Neoplasms / drug therapy. Salivary Gland Neoplasms / drug therapy. Thiocyanates / pharmacology


34. Masih I, Porter G, Porter S, Clarke R, Sidhu P, Harney J, McCarthy A, Convery R: Primary adenoid cystic carcinoma of the bronchus in a female teenager. BMJ Case Rep; 2010;2010
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  • [Title] Primary adenoid cystic carcinoma of the bronchus in a female teenager.
  • Primary adenoid cystic carcinoma (ACC) of the lung is an extremely rare malignant lung neoplasm.
  • ACC of salivary glands of the head and neck, lachrymal glands, breast, skin, vulva and trachea have been frequently reported disease patterns in the literature, but it is unique to see this rare lung tumour in a patient as young as 14 years old.
  • Our report of primary lung ACC in a young girl is a complex case due to young age, a different way of presentation and staging on diagnosis.
  • It has been a quite challenging clinical scenario for the multidisciplinary lung cancer treating team involved in the clinical care.
  • [MeSH-major] Carcinoma, Adenoid Cystic / diagnosis. Lung Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Biomarkers, Tumor / analysis. Biopsy, Needle. Chest Pain / etiology. Combined Modality Therapy. Cooperative Behavior. Female. Fluorodeoxyglucose F18. Humans. Interdisciplinary Communication. Lung / pathology. Multimodal Imaging. Neoplasm Staging. Pneumonectomy. Positron-Emission Tomography. Radiotherapy, Adjuvant. Shoulder Pain / etiology. Tomography, X-Ray Computed

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  • (PMID = 22798097.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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35. Quibell R, Baker L: Nicotine withdrawal and nicotine replacement in the palliative care setting. J Pain Symptom Manage; 2005 Sep;30(3):205-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adult. Aged. Breast Neoplasms / complications. Breast Neoplasms / therapy. Carcinoma, Adenoid Cystic / complications. Carcinoma, Adenoid Cystic / therapy. Carcinoma, Renal Cell / complications. Carcinoma, Renal Cell / therapy. Female. Humans. Kidney Neoplasms / complications. Kidney Neoplasms / therapy. Lung Neoplasms / complications. Lung Neoplasms / therapy. Parotid Neoplasms / complications. Parotid Neoplasms / therapy. Smoking / epidemiology

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  • (PMID = 16183003.001).
  • [ISSN] 0885-3924
  • [Journal-full-title] Journal of pain and symptom management
  • [ISO-abbreviation] J Pain Symptom Manage
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Nicotinic Agonists; 6M3C89ZY6R / Nicotine
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36. Xu Q, Liu X, Cai Y, Yu Y, Chen W: RNAi-mediated ADAM9 gene silencing inhibits metastasis of adenoid cystic carcinoma cells. Tumour Biol; 2010 Jun;31(3):217-24
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  • [Title] RNAi-mediated ADAM9 gene silencing inhibits metastasis of adenoid cystic carcinoma cells.
  • Here, we show that ADAM9 is highly expressed in metastatic cancer tissues and in an adenoid cystic carcinoma cell line with a high metastatic potential.
  • Using RNA interference for gene silencing, we show that ADAM9 is essential for in vitro cancer cell proliferation and invasion as well as in vivo cancer metastasis in an experimental murine model of lung metastases.
  • These data indicate that ADAM9 is potentially an important new therapeutic target for the prevention of tumor metastases in adenoid cystic carcinoma.
  • [MeSH-major] ADAM Proteins / antagonists & inhibitors. Carcinoma, Adenoid Cystic / therapy. Membrane Proteins / antagonists & inhibitors. RNA Interference

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  • (PMID = 20422344.001).
  • [ISSN] 1423-0380
  • [Journal-full-title] Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
  • [ISO-abbreviation] Tumour Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Membrane Proteins; EC 3.4.24.- / ADAM Proteins; EC 3.4.24.- / ADAM9 protein, human
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37. Unsal A, Karaman CZ, Kacar F, Sen S: [Atypically located pulmonary adenoid cystic carcinoma: case report]. Tuberk Toraks; 2008;56(2):210-4
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  • [Title] [Atypically located pulmonary adenoid cystic carcinoma: case report].
  • [Transliterated title] Atipik yerleşimli pulmoner adenoid kistik karsinom: Olgu sunumu.
  • Pulmonary adenoid cystic carcinomas typically arise from central extra-pulmonary airways and lung involvement is rare.
  • On the other hand, this entity should be kept in mind because it has a more favorable clinical course compared to the primary lung adenocarcinoma.
  • In this paper; the clinical, radiological and pathological aspects of a 47 years old man with a complaint of chronic cough, who was found to have a mass lesion at upper lobe of right lung and a final diagnosis of primary pulmonary adenoid cystic carcinoma according to transbronchial needle biopsy and pneumonectomy, was presented.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Lung Neoplasms / pathology. Pneumonectomy / methods
  • [MeSH-minor] Biopsy, Fine-Needle / methods. Bronchoscopy / methods. Diagnosis, Differential. Humans. Male. Middle Aged

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  • (PMID = 18701983.001).
  • [ISSN] 0494-1373
  • [Journal-full-title] Tüberküloz ve toraks
  • [ISO-abbreviation] Tuberk Toraks
  • [Language] tur
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Turkey
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38. Lai FY, Zhang Q, Wu QL, Qing J, Cao Y: [Expression and significance of E-cadherin in adenoid cystic carcinoma of the salivary glands]. Ai Zheng; 2007 Sep;26(9):1025-8
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  • [Title] [Expression and significance of E-cadherin in adenoid cystic carcinoma of the salivary glands].
  • This study was to explore the expression of E-cadherin in adenoid cystic carcinoma of the salivary glands and its correlations to nerve invasion, regional recurrence, distant metastasis and prognosis of this disease.
  • METHODS: The expression of E-cadherin in 55 specimens of adenoid cystic carcinoma of the salivary glands and 20 specimens of normal salivary gland tissue was detected by immunohistochemistry.
  • The positive rate of E-cadherin was significantly higher in normal salivary gland tissues than in adenoid cystic carcinoma tissues (90.0% vs.63.6%, P<0.05).
  • CONCLUSION: E-cadherin expression is down-regulated in adenoid cystic carcinoma of the salivary glands, which is correlated to nerve invasion, regional recurrence and distant metastasis.
  • [MeSH-major] Cadherins / metabolism. Carcinoma, Adenoid Cystic / metabolism. Salivary Gland Neoplasms / metabolism
  • [MeSH-minor] Adult. Aged. Cranial Nerve Neoplasms / pathology. Facial Nerve Diseases / pathology. Female. Follow-Up Studies. Humans. Lung Neoplasms / secondary. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Recurrence, Local. Radiotherapy, Adjuvant. Salivary Glands / metabolism. Salivary Glands / surgery. Survival Rate


39. Ko YH, Lee MA, Hong YS, Lee KS, Jung CK, Kim YS, Sun DI, Kim BS, Kim MS, Kang JH: Prognostic factors affecting the clinical outcome of adenoid cystic carcinoma of the head and neck. Jpn J Clin Oncol; 2007 Nov;37(11):805-11
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  • [Title] Prognostic factors affecting the clinical outcome of adenoid cystic carcinoma of the head and neck.
  • BACKGROUND: Adenoid cystic carcinoma (ACC) is an uncommon tumor, constituting approximately 10% of all head and neck tumors.
  • METHODS: We performed a retrospective study of 42 patients who underwent primary tumor resection or radiotherapy with curative intent and evaluated the clinical parameters, treatment and clinical outcomes.
  • Of the 32 patients in whom recurrence could be evaluated, 18 (56.3%) developed distant metastases, with the lung (72.2%) being the most common site.
  • Perivascular invasion influenced metastasis to the lung with borderline significance (P = 0.053).
  • [MeSH-major] Carcinoma, Adenoid Cystic / mortality. Head and Neck Neoplasms / mortality

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  • (PMID = 18057012.001).
  • [ISSN] 1465-3621
  • [Journal-full-title] Japanese journal of clinical oncology
  • [ISO-abbreviation] Jpn. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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40. Mustonen T, Sovijärvi AR, Piirilä P: Occult tracheal tumour detected by lung function tests. Clin Respir J; 2009 Jan;3(1):59-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Occult tracheal tumour detected by lung function tests.
  • [MeSH-major] Airway Obstruction / etiology. Carcinoma, Adenoid Cystic / diagnosis. Peak Expiratory Flow Rate. Tracheal Neoplasms / diagnosis
  • [MeSH-minor] Biopsy, Needle. Bronchoscopy / methods. Dyspnea / diagnosis. Dyspnea / etiology. Female. Follow-Up Studies. Humans. Immunohistochemistry. Middle Aged. Neoplasm Staging. Radiotherapy, Adjuvant. Respiratory Function Tests. Risk Assessment. Thoracic Surgical Procedures / methods. Tomography, X-Ray Computed / methods. Treatment Outcome

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  • (PMID = 20298375.001).
  • [ISSN] 1752-699X
  • [Journal-full-title] The clinical respiratory journal
  • [ISO-abbreviation] Clin Respir J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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41. Yen YT, Lai WW: Right thoracotomy for carinal resection with left thoracoscopic pneumonectomy as a new approach for left sleeve pneumonectomy: a case report. Kaohsiung J Med Sci; 2010 Nov;26(11):609-14
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  • A biopsy proved the tumor to be adenoid cystic carcinoma.
  • The distance between the tumor-free left main bronchus and the carina was large; therefore, preservation of the left lung would have compromised the healing of the carinal tracheobronchoplasty and led to life-threatening complications.

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  • [Copyright] Copyright © 2010 Elsevier. Published by Elsevier B.V. All rights reserved.
  • (PMID = 21126714.001).
  • [ISSN] 1607-551X
  • [Journal-full-title] The Kaohsiung journal of medical sciences
  • [ISO-abbreviation] Kaohsiung J. Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
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42. Yang PY, Liu MS, Chen CH, Lin CM, Tsao TC: Adenoid cystic carcinoma of the trachea: a report of seven cases and literature review. Chang Gung Med J; 2005 May;28(5):357-63
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  • [Title] Adenoid cystic carcinoma of the trachea: a report of seven cases and literature review.
  • BACKGROUND: Adenoid cystic carcinoma (ACC) of the trachea is rare.
  • For these seven patients the clinical manifestations and period from initial symptoms to diagnosis, treatment and outcome are presented.
  • In one patient with the tumor in the lower area of the trachea, the tumor invaded the right lower lobe of the lung.
  • CONCLUSIONS: ACC is a rare primary tracheal malignancy.
  • The time from first symptoms to diagnosis varied, ranging from weeks to more than 1 year.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Tracheal Neoplasms / pathology

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  • (PMID = 16086551.001).
  • [ISSN] 2072-0939
  • [Journal-full-title] Chang Gung medical journal
  • [ISO-abbreviation] Chang Gung Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China (Republic : 1949- )
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43. Su T, Sun HC, Zang GX, Zhang H, Lu DM: [Inhibition of proliferation of salivary adenoid cystic carcinoma by targeting gene transfer]. Zhonghua Kou Qiang Yi Xue Za Zhi; 2007 Mar;42(3):184-5
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  • [Title] [Inhibition of proliferation of salivary adenoid cystic carcinoma by targeting gene transfer].
  • RESULTS: Expression of extrinsic TRAIL gene driven by hTERT promoter was detected in SACC-83 cells, and not detected in human embryonic lung fibroblast (HEL) cells.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Salivary Gland Neoplasms / pathology. TNF-Related Apoptosis-Inducing Ligand / genetics. Telomerase / genetics

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  • (PMID = 17565833.001).
  • [ISSN] 1002-0098
  • [Journal-full-title] Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
  • [ISO-abbreviation] Zhonghua Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / TNF-Related Apoptosis-Inducing Ligand; EC 2.7.7.49 / TERT protein, human; EC 2.7.7.49 / Telomerase
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44. Mohindroo S, Sharma JS: Metastatic adenoid cystic carcinoma of lung: a case report. Indian J Pathol Microbiol; 2006 Oct;49(4):597-9
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  • [Title] Metastatic adenoid cystic carcinoma of lung: a case report.
  • A 48 year old male patient, operated five years back for sub mandibular swelling proved on histopathologic examination to be adenoid cystic carcinoma presented in the ENT department, I. G. medical hospital with pain on both sides of the chest.
  • CT guided FNAC as well as biopsy of the lung lesion was performed.
  • Cytodiagnosis and histopathological examinations revealed features of cribiform type of adenoid cystic carcinoma.
  • [MeSH-major] Carcinoma, Adenoid Cystic / secondary. Lung Neoplasms / secondary

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  • (PMID = 17183870.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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45. Lin TT, He YJ, Zhang H, Song GX, Tang DR, Zhao HF: [Analysis of treatment and prognosis of orbital adenoid cystic carcinoma]. Zhonghua Yan Ke Za Zhi; 2009 Apr;45(4):309-13
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  • [Title] [Analysis of treatment and prognosis of orbital adenoid cystic carcinoma].
  • OBJECTIVE: To summarize the treatment outcomes of orbital adenoid cystic carcinoma and to evaluate prognostic factors.
  • METHOD: A retrospective case series study was performed on 75 patients with orbital adenoid cystic carcinoma treated from 1991 to 2006.
  • RESULTS: The 2- and 5-year local recurrence rate of solid type orbital adenoid cystic carcinoma was significantly higher than that of the adeno-tubiform type [2-year, 85% (17/20) vs 23.53% (8/34), chi(2) = 19.14, P = 0.000; 5-year, 100% (19/19) vs 64.52% (20/31), Fisher's exact test, P = 0.003].
  • They may spread to the lung, bone, liver and lymph node.
  • Both of the lung and bone metastasis rates were 33.33% (3/9).
  • CONCLUSIONS: Orbital adenoid cystic carcinoma is one of the most malignant tumors in the orbit.
  • [MeSH-major] Carcinoma, Adenoid Cystic / therapy. Orbital Neoplasms / therapy

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  • (PMID = 19575961.001).
  • [ISSN] 0412-4081
  • [Journal-full-title] [Zhonghua yan ke za zhi] Chinese journal of ophthalmology
  • [ISO-abbreviation] Zhonghua Yan Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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46. De Dosso S, Mazzucchelli L, Ghielmini M, Saletti P: Response to oxaliplatin with cetuximab in minor salivary gland adenoid cystic carcinoma. Tumori; 2009 May-Jun;95(3):378-81
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  • [Title] Response to oxaliplatin with cetuximab in minor salivary gland adenoid cystic carcinoma.
  • Esophageal localization of adenoid cystic carcinoma of minor salivary glands is rare; it may occur in the early to mid-sixties' age group and is more frequently encountered in men than women.
  • In the majority of cases, it arises from subepithelial glands of the middle to lower third of the esophagus, a similar distribution as squamous cell carcinoma.
  • We report a case of a patient with metastatic primary esophageal adenoid cystic carcinoma progressing on platinum- and irinotecan-based regimens, who achieved an objective response with oxaliplatin-based chemotherapy in combination with cetuximab.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinoma, Adenoid Cystic / drug therapy. Carcinoma, Adenoid Cystic / secondary. Esophageal Neoplasms / pathology. Salivary Gland Neoplasms / drug therapy. Salivary Gland Neoplasms / secondary
  • [MeSH-minor] Antibodies, Monoclonal / administration & dosage. Antibodies, Monoclonal, Humanized. Biomarkers, Tumor / analysis. Cetuximab. Humans. Lung Neoplasms / drug therapy. Lung Neoplasms / pathology. Male. Middle Aged. Organoplatinum Compounds / administration & dosage. Receptor, Epidermal Growth Factor / analysis. Treatment Outcome

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  • (PMID = 19688981.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 0 / Biomarkers, Tumor; 0 / Organoplatinum Compounds; 04ZR38536J / oxaliplatin; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; PQX0D8J21J / Cetuximab
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47. Rusu P, Ciuleanu TE, Cernea D, Pelau D, Gaal V, Cebotaru C, Guttman T, Todor N, Ghilezan N: Concurrent chemoradiotherapy with vinorelbine and a platinum compound followed by consolidation chemotherapy for unresectable stage III non-small cell lung cancer: preliminary results of a phase II study. J BUON; 2007 Jan-Mar;12(1):33-9
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  • [Title] Concurrent chemoradiotherapy with vinorelbine and a platinum compound followed by consolidation chemotherapy for unresectable stage III non-small cell lung cancer: preliminary results of a phase II study.
  • PURPOSE: To determine the efficacy, toxicity and survival of concurrent therapy with vinorelbine and a platinum compound with radiotherapy (RT), followed by consolidation chemotherapy with the same drugs, for locally advanced non small cell lung cancer (NSCLC).
  • PATIENTS AND METHODS: Fifty-seven patients with stage III NSCLC were included in this phase II study: median age 56 years (range 44-71), males / females 49/8, ECOG performance status (PS) 1/2=27/30, stage IIIA/ IIIB 11/46, squamous cell carcinoma 44, adenocarcinoma 7, adenoid cystic carcinoma 1 and large cell carcinoma 5.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinoma, Non-Small-Cell Lung / drug therapy. Carcinoma, Non-Small-Cell Lung / radiotherapy. Lung Neoplasms / drug therapy. Lung Neoplasms / radiotherapy

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  • (PMID = 17436399.001).
  • [ISSN] 1107-0625
  • [Journal-full-title] Journal of B.U.ON. : official journal of the Balkan Union of Oncology
  • [ISO-abbreviation] J BUON
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase II; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; 0 / Radiation-Protective Agents; 5V9KLZ54CY / Vinblastine; BG3F62OND5 / Carboplatin; M487QF2F4V / Amifostine; Q20Q21Q62J / Cisplatin; Q6C979R91Y / vinorelbine
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48. Shi H, Wang J, Dong F, Wang X, Li H, Hou Y: The effect of proteoglycans inhibited by RNA interference on metastatic characters of human salivary adenoid cystic carcinoma. BMC Cancer; 2009;9:456
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  • [Title] The effect of proteoglycans inhibited by RNA interference on metastatic characters of human salivary adenoid cystic carcinoma.
  • BACKGROUND: Salivary adenoid cystic carcinoma (SACC) is one of the most common malignancies of salivary gland.
  • However, there is rare study of the effect of proteoglycans on the potential metastasis of SACC.In this study, human xylosyltransferase-I (XTLY-I) gene, which catalyzes the rate-limited step of proteoglycans biosynthesis, was knocked down by RNA interference (RNAi) to inhibit the proteoglycans biosynthesis in SACC cell line with high tendency of lung metastasis (SACC-M).
  • The invasion and metastasis of SACC-M-WJ4 cells were detected; the effect of down-regulated proteoglycans on the potential lung metastasis of nude mice was observed, respectively.
  • The reduction of proteoglycans suppressed the adhesion, invasion and metastasis properties of SACC-M cells, and decreased the lung metastasis of SACC-M cells markedly either.
  • [MeSH-major] Carcinoma, Adenoid Cystic / drug therapy. Pentosyltransferases / antagonists & inhibitors. Proteoglycans / antagonists & inhibitors. RNA, Small Interfering / pharmacology. Salivary Gland Neoplasms / drug therapy

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  • (PMID = 20025737.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Proteoglycans; 0 / RNA, Small Interfering; EC 2.4.2.- / Pentosyltransferases; EC 2.4.2.26 / UDP xylose-protein xylosyltransferase
  • [Other-IDs] NLM/ PMC2805682
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49. Qin M, Fu Y, Yu D, Xu S, Han M, Wang Z: [Diagnosis and treatment of tracheal or bronchuotracheal adenoid cystic carcinoma]. Zhongguo Fei Ai Za Zhi; 2010 Jun;13(6):628-31
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  • [Title] [Diagnosis and treatment of tracheal or bronchuotracheal adenoid cystic carcinoma].
  • BACKGROUND AND OBJECTIVE: Adenoid cystic carcinoma is primary bronchopulmonary carcinoma with low malignancy, and 43 patients treated in the past 50 years in our hospital were retrospectively studied.
  • The aim of this study is to discuss the clinical symptoms, pathologic characteristic and therapeutic method of primary tracheal or bronchuotracheal adenoid cystic carcinoma.
  • METHODS: This study summarized total 43 patients of primary tracheal or bronchus adenoid cystic carcinoma treated in our hospital from Jan.
  • CONCLUSION: Primary tracheal or bronchus adenoid cystic carcinoma are rare and low malignancy carcinoma.
  • [MeSH-major] Bronchial Neoplasms / surgery. Carcinoma, Adenoid Cystic / surgery. Tracheal Neoplasms / surgery

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  • (PMID = 20681452.001).
  • [ISSN] 1009-3419
  • [Journal-full-title] Zhongguo fei ai za zhi = Chinese journal of lung cancer
  • [ISO-abbreviation] Zhongguo Fei Ai Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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50. Wei MH, Tang PZ, Xu ZG, Qi YF, Yin YL: [Clinical analysis of 40 cases with sinonasal adenoid cystic carcinoma]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2009 May;44(5):381-4
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  • [Title] [Clinical analysis of 40 cases with sinonasal adenoid cystic carcinoma].
  • OBJECTIVE: To study the clinical characters and the mode of treatment, and to analyze the prognosis of patients with sinonasal adenoid cystic carcinoma.
  • METHODS: The clinical data were analyzed retrospectively in 40 patients with sinonasal adenoid cystic carcinoma.
  • The most common site of distant metastasis was lung.
  • CONCLUSIONS: Distant metastasis is an important factor affecting the prognosis of the patients with sinonasal adenoid cystic carcinoma.
  • Combined therapy composed of surgery and radiation was the first choice of treatment to the patients with sinonasal adenoid cystic carcinoma.
  • [MeSH-major] Carcinoma, Adenoid Cystic / therapy. Paranasal Sinus Neoplasms / therapy

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  • (PMID = 19567046.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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51. Patel AA, Gupta D, Seligson D, Hattab EM, Balis UJ, Ulbright TM, Kohane IS, Berman JJ, Gilbertson JR, Dry S, Schirripa O, Yu H, Becich MJ, Parwani AV, Shared Pathology Informatics Network: Availability and quality of paraffin blocks identified in pathology archives: a multi-institutional study by the Shared Pathology Informatics Network (SPIN). BMC Cancer; 2007 Feb 28;7:37
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  • Each site generated a list of 100 common tumor cases (25 cases each of breast adenocarcinoma, colonic adenocarcinoma, lung squamous carcinoma, and prostate adenocarcinoma) and 100 rare tumor cases (25 cases each of adrenal cortical carcinoma, gastro-intestinal stromal tumor [GIST], adenoid cystic carcinoma, and mycosis fungoides) using a combination of Tumor Registry, laboratory information system (LIS) and/or SPIN-related tools.
  • Retrieval rate (tumor blocks) from all centers for common tumors was 73% with mean largest tumor size of 1.49 cm; retrieval (tumor blocks) was highest-lung (84%) and lowest-prostate (54%).
  • Retrieval rate (tumor blocks) from all centers for rare tumors was 66% with mean largest tumor size of 1.56 cm; retrieval (tumor blocks) was highest for GIST (72%) and lowest for adenoid cystic carcinoma (58%).

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  • (PMID = 17386082.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / U01CA091343; United States / NCI NIH HHS / CA / U01 CA091429; United States / NCI NIH HHS / CA / U01CA091429; United States / NCI NIH HHS / CA / P30 CA016042; United States / NCI NIH HHS / CA / U01 CA091343; United States / NCI NIH HHS / CA / UO1CA91338-01
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1810540
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52. Chopra R, Mendenhall WM, Morris CG, Zlotecki RA, Olivier KR: Surgery and postoperative radiotherapy for adenoid cystic carcinoma of the lung. Am J Clin Oncol; 2006 Aug;29(4):420-1
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  • [Title] Surgery and postoperative radiotherapy for adenoid cystic carcinoma of the lung.
  • [MeSH-major] Carcinoma, Adenoid Cystic / radiotherapy. Lung Neoplasms / radiotherapy

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  • (PMID = 16891874.001).
  • [ISSN] 1537-453X
  • [Journal-full-title] American journal of clinical oncology
  • [ISO-abbreviation] Am. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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53. Qing J, Zhang Q, Wei MW, Guo ZM: [Prognostic analysis of adenoid cystic carcinoma of major salivary glands of 64 cases]. Ai Zheng; 2006 Sep;25(9):1138-43
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  • [Title] [Prognostic analysis of adenoid cystic carcinoma of major salivary glands of 64 cases].
  • BACKGROUND & OBJECTIVE: Adenoid cystic carcinoma of salivary glands is a kind of highly malignant tumor, and researches on the tumors originated from major salivary glands are rare.
  • This study was to investigate prognostic factors of adenoid cystic carcinoma of major salivary glands.
  • METHODS: Clinical records of 64 patients with adenoid cystic carcinoma of major salivary glands followed up for more than 7 years were reviewed.
  • CONCLUSION: Presence or absence of nerve invasion, histological subtype, clinical stage, and positive or negative surgical margin are the independent factors affecting the prognosis of patients with adenoid cystic carcinoma of salivary glands.
  • [MeSH-major] Carcinoma, Adenoid Cystic / secondary. Lung Neoplasms / secondary. Salivary Gland Neoplasms / pathology


54. Hu JA, Li Y, Fang J: Effect of ERK inhibitor on pulmonary metastasis of inoculated human adenoid cystic carcinoma cells in nude mice. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Jan;109(1):117-23
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  • [Title] Effect of ERK inhibitor on pulmonary metastasis of inoculated human adenoid cystic carcinoma cells in nude mice.
  • In this study, we detected the expression of phosphylated ERK1/2 in human salivary adenoid cystic carcinoma (SACC) by immunohistochemical method, the effect of various concentrations of PD98059 on the growth of ACC-M cells (a cell line of human adenoid cystic carcinoma of the salivary glands) by MTT assay, and the effect of PD98059 on the lung metastasis of inoculated ACC-M cells in nude mice.
  • The results showed that the phosphylated ERK1/2 was overexpressed in SACC, the ACC-M cell line proliferation was inhibited by PD98059, and the lung metastasis level was reduced by PD98059, indicating that ERK may be a key molecule in targeted therapy of adenoid cystic carcinoma.
  • [MeSH-major] Carcinoma, Adenoid Cystic / enzymology. Carcinoma, Adenoid Cystic / secondary. Extracellular Signal-Regulated MAP Kinases / antagonists & inhibitors. Lung Neoplasms / enzymology. Lung Neoplasms / secondary. Protein Kinase Inhibitors / pharmacology. Salivary Gland Neoplasms / pathology

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  • [Copyright] Copyright 2010 Mosby, Inc. All rights reserved.
  • (PMID = 20123382.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one; 0 / Flavonoids; 0 / Protein Kinase Inhibitors; EC 2.7.11.24 / Extracellular Signal-Regulated MAP Kinases
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55. Yamada T, Mouri H, Izumi K, Takeuchi S, Ohtsubo K, Yamashita K, Yasumoto K, Kitamura S, Yano S: [Combined chemotherapy with cisplatin plus vinorelbine showed efficacy in a case of metastatic primary cutaneous adenoid cystic carcinoma]. Gan To Kagaku Ryoho; 2010 Aug;37(8):1545-8
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  • [Title] [Combined chemotherapy with cisplatin plus vinorelbine showed efficacy in a case of metastatic primary cutaneous adenoid cystic carcinoma].
  • We report a case of a 65-year-old man with metastatic primary cutaneous adenoid cystic carcinoma that was effectively treated by combination chemotherapy with cisplatin (CDDP) plus vinorelbine(VNR).
  • He was given a diagnosis of primary cutaneous adenoid cystic carcinoma with metastatic lesions to multiple lungs and left tibial bone and then given chemotherapy combining CDDP plus VNR as the first treatment in December 2008.
  • By this treatment for six cycles, the lung metastatic tumors gradually reduced on chest CT.
  • We reported the efficacy of combined treatment with CDDP plus VNR for primary cutaneous adenoid cystic carcinoma, because this clinical condition was very rare and the standard treatment has still not been established.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinoma, Adenoid Cystic / drug therapy. Cisplatin / therapeutic use. Lung Neoplasms / drug therapy. Skin Neoplasms / drug therapy. Vinblastine / analogs & derivatives

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  • (PMID = 20716883.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 5V9KLZ54CY / Vinblastine; Q20Q21Q62J / Cisplatin; Q6C979R91Y / vinorelbine
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56. Yu Y, Guo W, Qiu WL, Zhou XJ: [Experimental study of hydroxycamptothecine and theprubicine in the treatment of adenoid cystic carcinoma lung metastases]. Zhonghua Kou Qiang Yi Xue Za Zhi; 2006 May;41(5):291-4
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  • [Title] [Experimental study of hydroxycamptothecine and theprubicine in the treatment of adenoid cystic carcinoma lung metastases].
  • OBJECTIVE: To investigate anticancer effect of hydroxycamptothecine and theprubicine in the treatment of established human adenoid cystic carcinoma (ACC) lung metastasis of nude mice and to determine the best therapy sequence of the two drugs.
  • METHODS: The model of ACC lung metastasis (60 animals) was established by injecting the ACC-M cells into the nude mice from their tail veins.
  • The lung samples were collected and observed after HE staining.
  • The area of metastases and lung tissue were analyzed by the images analysis system.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Lung Neoplasms / drug therapy
  • [MeSH-minor] Animals. Camptothecin / administration & dosage. Camptothecin / analogs & derivatives. Carcinoma, Adenoid Cystic / secretion. Epirubicin / administration & dosage. Female. Humans. Male. Mice. Mice, Nude. Salivary Gland Neoplasms / pathology. Tumor Cells, Cultured

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  • (PMID = 16784612.001).
  • [ISSN] 1002-0098
  • [Journal-full-title] Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
  • [ISO-abbreviation] Zhonghua Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 3Z8479ZZ5X / Epirubicin; 67656-30-8 / 10-hydroxycamptothecin; XT3Z54Z28A / Camptothecin
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57. Dahse R, Kosmehl H: Detection of drug-sensitizing EGFR exon 19 deletion mutations in salivary gland carcinoma. Br J Cancer; 2008 Jul 8;99(1):90-2
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  • [Title] Detection of drug-sensitizing EGFR exon 19 deletion mutations in salivary gland carcinoma.
  • Activating mutations within the epidermal growth factor receptor (EGFR) identify lung adenocarcinoma patients with improved clinical responses to tyrosine kinase inhibitors gefitinib and erlotinib.
  • By screening salivary gland carcinoma, two drug-sensitizing EGFR exon 19 delE746-A750 mutations were identified in an adenocystic and in a mucoepidermoid carcinoma of the parotid gland.
  • [MeSH-minor] Aged. Carcinoma, Adenoid Cystic / drug therapy. Carcinoma, Adenoid Cystic / genetics. Carcinoma, Mucoepidermoid / drug therapy. Carcinoma, Mucoepidermoid / genetics. DNA, Neoplasm / genetics. Erlotinib Hydrochloride. Exons. Female. Humans. Male. Middle Aged. Mutation. Quinazolines / therapeutic use

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  • [Cites] Science. 2004 Jun 4;304(5676):1497-500 [15118125.001]
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  • (PMID = 18542074.001).
  • [ISSN] 1532-1827
  • [Journal-full-title] British journal of cancer
  • [ISO-abbreviation] Br. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DNA, Neoplasm; 0 / Protein Kinase Inhibitors; 0 / Quinazolines; DA87705X9K / Erlotinib Hydrochloride; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; S65743JHBS / gefitinib
  • [Other-IDs] NLM/ PMC2453031
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58. Bölükbas S, Schirren J: Parenchyma-sparing bronchial sleeve resections in trauma, benign and malign diseases. Thorac Cardiovasc Surg; 2010 Feb;58(1):32-7
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  • RESULTS: From January 1999 through December 2008, 19 patients (11 male) underwent bronchial sleeve resection without removal of pulmonary parenchyma.
  • Indications were carcinoid tumors (n = 14), adenoid cystic carcinoma (n = 1), non-small cell lung cancer (n = 1), blunt chest trauma (n = 2) and stenosis (n = 1).
  • Resections were complete except for the resection of the adenoid cystic carcinoma (n = 1, R1 resection).
  • [MeSH-major] Bronchi / surgery. Bronchial Diseases / surgery. Pulmonary Surgical Procedures / methods

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  • (PMID = 20072974.001).
  • [ISSN] 1439-1902
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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59. Murinello N, Vitorino ME, Matos C, Correia JM, Lima M, Baptista P, Sena Lino J, Nogueira F: [Recurrent adenoid cystic carcinoma. Review based on a case report]. Rev Port Pneumol; 2009 Jan-Feb;15(1):101-7
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  • [Title] [Recurrent adenoid cystic carcinoma. Review based on a case report].
  • [Transliterated title] Carcinoma adenóide quístico recorrente. Revisão a propósito de um caso clínico.
  • The adenoid cystic carcinoma is a malignant epithelial glandular type neoplasia, occurring frequently in the salivary and mammary glands, and rarely in the lung, and is responsible for 0.2% of lung tumours.
  • The authors present a case of a woman with adenoid cystic lung carcinoma diagnosed after investigation of a lung nodule, submitted to surgical resection with curative intention, whose follow -up identified late recurrence, 9 years after surgery.
  • The article reviews clinical and pathological features of lung adenoid cystic carcinoma, as well as therapeutic options, namely for prevention of recurrence.
  • [MeSH-major] Carcinoma, Adenoid Cystic. Lung Neoplasms. Neoplasm Recurrence, Local

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  • (PMID = 19145392.001).
  • [ISSN] 0873-2159
  • [Journal-full-title] Revista portuguesa de pneumologia
  • [ISO-abbreviation] Rev Port Pneumol
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Portugal
  • [Number-of-references] 10
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60. Kumar T, Patel N, Talwar A: Spontaneous regression of thoracic malignancies. Respir Med; 2010 Oct;104(10):1543-50
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  • Using a modified Everson and Cole criterion we developed to define spontaneous regression, this search was refined for true spontaneous regression of primary and metastatic thoracic malignancies.
  • RESULTS: Only 5 cases in the literature involved spontaneous regression of a primary thoracic malignancy.
  • These include pleural mesothelioma, primary lung cancer and adenoid cystic carcinoma.
  • 71 cases involved true spontaneous regression of metastatic thoracic neoplasms, of which 5 cases showed regression of the primary extrapulmonary tumors along with the pulmonary metastasis.
  • Thoracic metastasis from renal cell carcinoma was the most common malignancy found to regress spontaneously.
  • CONCLUSION: Spontaneous regression of primary thoracic malignancy is rare.
  • Renal cell carcinoma accounts for most reported cases.
  • [MeSH-major] Carcinoma, Renal Cell / epidemiology. Kidney Neoplasms / epidemiology. Neoplasm Regression, Spontaneous. Pleural Neoplasms / epidemiology. Thoracic Neoplasms / epidemiology

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  • (PMID = 20580882.001).
  • [ISSN] 1532-3064
  • [Journal-full-title] Respiratory medicine
  • [ISO-abbreviation] Respir Med
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 81
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61. Aksu K, Aktaş Z, Aksu F, Orsel O, Demirağ F, Sipit T, Firat Güven S: Spindle cell sarcomatoid carcinoma: first case reported in the trachea. Tuberk Toraks; 2009;57(3):337-41
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  • [Title] Spindle cell sarcomatoid carcinoma: first case reported in the trachea.
  • Microscopically, the tumor was composed of fascicular pattern of spindle cells with atypical mitotic figures and nuclear pleomorphism, positively reactive to epithelial membrane antigen supporting a diagnosis of tumour with epithelial differentiation.
  • These findings supported the diagnosis of a spindle cell sarcomatoid carcinoma of trachea.
  • Spindle cell carcinoma cases are reported in many sites, such as head and neck region, larynx, digestive tract, breast, kidney, genital tract, skin and lung, but to our knowledge, not in trachea.
  • Primary malignant tracheal tumours consist mainly of squamous cell carcinoma and adenoid cystic carcinoma and generally have an aggressive course with poor prognosis.
  • We report the first presentation of a spindle cell sarcomatoid carcinoma of trachea together with the clinical course of the patient.
  • [MeSH-major] Carcinoma / pathology. Tracheal Neoplasms / pathology

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  • (PMID = 19787474.001).
  • [ISSN] 0494-1373
  • [Journal-full-title] Tüberküloz ve toraks
  • [ISO-abbreviation] Tuberk Toraks
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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62. Bell D, Roberts D, Kies M, Rao P, Weber RS, El-Naggar AK: Cell type-dependent biomarker expression in adenoid cystic carcinoma: biologic and therapeutic implications. Cancer; 2010 Dec 15;116(24):5749-56
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  • [Title] Cell type-dependent biomarker expression in adenoid cystic carcinoma: biologic and therapeutic implications.
  • BACKGROUND: Adenoid cystic carcinoma (ACC), a rare and progressive salivary malignancy, is characterized by cellular, morphologic, and clinical heterogeneity.

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  • [Copyright] Copyright © 2010 American Cancer Society.
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  • (PMID = 20824717.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P30 CA016672; United States / NIDCR NIH HHS / DE / U01 DE019765; United States / NIDCR NIH HHS / DE / U01DE019756; United States / NCI NIH HHS / CA / CA16672; United States / NIDCR NIH HHS / DE / U01 DE019765-01
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit; EC 2.7.10.1 / Receptor, Epidermal Growth Factor
  • [Other-IDs] NLM/ NIHMS219730; NLM/ PMC2998592
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63. Minamiya Y, Saito H, Ogawa J: [Experience of twenty-one cases of tracheo-bronchoplasty]. Kyobu Geka; 2008 Oct;61(11):920-6
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  • There are 14 cases of squamous cell carcinoma, 3 cases of adenocarcinoma, 2 cases of adenoid cystic carcinoma, 1 case of inflammatory tracheal stenosis, and 1 case of inflammatory bronchial stenosis.
  • Of 3 cases, we added sleeve resection of pulmonary artery.
  • [MeSH-major] Adenocarcinoma / surgery. Bronchi / surgery. Carcinoma, Adenoid Cystic / surgery. Carcinoma, Squamous Cell / surgery. Lung Neoplasms / surgery. Pneumonectomy / methods. Reconstructive Surgical Procedures / methods. Trachea / surgery. Tracheal Stenosis / surgery

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  • (PMID = 18939426.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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64. Florentine BD, Fink T, Avidan S, Braslavsky D, Raza A, Cobb CJ: Extra-salivary gland presentations of adenoid cystic carcinoma: a report of three cases. Diagn Cytopathol; 2006 Jul;34(7):491-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extra-salivary gland presentations of adenoid cystic carcinoma: a report of three cases.
  • Adenoid cystic carcinoma (ACC) is a malignant neoplasm most commonly originating in salivary glands of the head and neck area.
  • When ACC presents outside of these locations, the diagnosis may become more challenging.
  • Two cases were metastatic; in case 1 the initial presentation was widespread bony metastasis of unknown primary origin.
  • The other metastatic case (case 2) was from a patient presenting with a pleural effusion and a history of previously treated metastatic pulmonary ACC.
  • Case 3 was a primary bronchial ACC.
  • In conclusion, ACC can present in various body sites and cytologists must consider this neoplasm when presented with a basaloid carcinoma of uncertain origin.
  • [MeSH-major] Bone Neoplasms / secondary. Carcinoma, Adenoid Cystic / secondary. Lung Neoplasms / secondary. Pleural Effusion / pathology
  • [MeSH-minor] Aged. Aged, 80 and over. Biopsy, Fine-Needle. Female. Humans. Middle Aged. Neoplasms, Unknown Primary

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  • [Copyright] Copyright 2006 Wiley-Liss, Inc.
  • (PMID = 16783770.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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65. Kitada M, Ozawa K, Sato K, Hayashi S, Tokusashi Y, Miyokawa N, Sasajima T: Adenoid cystic carcinoma of the peripheral lung: a case report. World J Surg Oncol; 2010;8:74
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  • [Title] Adenoid cystic carcinoma of the peripheral lung: a case report.
  • Adenoid cystic carcinoma of the peripheral lung is a rare entity.
  • We recently encountered a patient with adenoid cystic carcinoma.
  • A 75-year-old woman showed a nodular lesion with 10 mm in diameter in the right upper lung field on chest radiography.
  • The diagnosis was unclear, but lung cancer could not be ruled out.
  • Thoracoscopic biopsy was performed, and intraoperative pathological diagnosis revealed the carcinoma of the lung.
  • Histopathological examination revealed adenoid cystic carcinoma with a characteristic cribriform structure.
  • Immunohistochemical examination revealed that the tumor cells were positive for thyroid transcription factor 1 (TTF-1), this tumor was diagnosed primary ACC of the lung.
  • [MeSH-major] Carcinoma, Adenoid Cystic / diagnosis. Lung Neoplasms / diagnosis
  • [MeSH-minor] Aged. Diagnosis, Differential. Female. Humans. Pneumonectomy / methods. Radiography, Thoracic. Thoracic Surgery, Video-Assisted / methods. Tomography, X-Ray Computed

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  • (PMID = 20796281.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2936894
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66. Sayar A, Metin M, Solak O, Turna A, Alzafer S, Ece T: A new surgical technique for adenoid cystic carcinoma involving tracheal carina. Asian Cardiovasc Thorac Ann; 2005 Sep;13(3):280-2
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  • [Title] A new surgical technique for adenoid cystic carcinoma involving tracheal carina.
  • Reported is the successful treatment of a 24-year-old male with adenocystic carcinoma involving the tracheal carina, in which the tumor extended along the right main bronchus across the orifice of the right upper lobe.
  • [MeSH-major] Bronchial Neoplasms / surgery. Carcinoma, Adenoid Cystic / surgery. Lung Neoplasms / surgery. Tracheal Neoplasms / surgery

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  • (PMID = 16113006.001).
  • [ISSN] 0218-4923
  • [Journal-full-title] Asian cardiovascular & thoracic annals
  • [ISO-abbreviation] Asian Cardiovasc Thorac Ann
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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67. Seethala RR, Hunt JL, Baloch ZW, Livolsi VA, Leon Barnes E: Adenoid cystic carcinoma with high-grade transformation: a report of 11 cases and a review of the literature. Am J Surg Pathol; 2007 Nov;31(11):1683-94
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  • [Title] Adenoid cystic carcinoma with high-grade transformation: a report of 11 cases and a review of the literature.
  • High-grade transformation of adenoid cystic carcinoma (ACC) (previously referred to as dedifferentiation) is a rare phenomenon that does not fit into the traditional ACC grading schemes.
  • Distant metastases to the lung (n=2) and soft tissue of the shoulder (n=1) were observed.
  • The most common morphologies for the high-grade component were poorly differentiated cribriform adenocarcinoma and solid undifferentiated carcinoma.
  • [MeSH-major] Adenocarcinoma / pathology. Carcinoma, Adenoid Cystic / pathology. Carcinoma, Papillary / pathology. Carcinoma, Squamous Cell / pathology. Cell Transformation, Neoplastic / pathology. Salivary Gland Neoplasms / pathology


68. Sato N, Watanabe T, Miyamoto A, Imai T, Ebina A, Katto K, Watanabe S: [The role of postoperative radiotherapy in non-small cell lung cancer; a retrospective analysis of our experience]. Kyobu Geka; 2008 Jan;61(1):19-23
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  • [Title] [The role of postoperative radiotherapy in non-small cell lung cancer; a retrospective analysis of our experience].
  • Sixty-one patients with completely resected non-small cell lung cancer followed by postoperative radiotherapy were retrospectively reviewed.
  • Squamous cell carcinoma (scc) in 28, adenoca. in 31, large cell ca in 1 and adenoid cystic ca. in 1.
  • [MeSH-major] Carcinoma, Non-Small-Cell Lung / radiotherapy. Lung Neoplasms / radiotherapy


69. Shamim T, Varghese VI, Shameena PM, Sudha S: Primary intraosseous adenoid cystic carcinoma of the mandible with lung metastasis: a case report. J Oral Sci; 2008 Mar;50(1):95-8
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  • [Title] Primary intraosseous adenoid cystic carcinoma of the mandible with lung metastasis: a case report.
  • Intraosseous adenoid cystic carcinoma is an extremely rare neoplasm with only 17 cases reported previously.
  • A case of primary intraosseous adenoid cystic carcinoma of the mandible with lung metastasis in a 45-year-old man is reported, together with a brief review of the literature.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Lung Neoplasms / secondary. Mandibular Neoplasms / pathology. Solitary Pulmonary Nodule / secondary
  • [MeSH-minor] Biopsy, Fine-Needle. Diagnosis, Differential. Humans. Male. Middle Aged

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  • (PMID = 18403891.001).
  • [ISSN] 1343-4934
  • [Journal-full-title] Journal of oral science
  • [ISO-abbreviation] J Oral Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 10
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70. Pogodzinski MS, Sabri AN, Lewis JE, Olsen KD: Retrospective study and review of polymorphous low-grade adenocarcinoma. Laryngoscope; 2006 Dec;116(12):2145-9
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  • One patient had regional nodal disease 20 years after the initial procedure, and another had lung metastasis.
  • The most common initial diagnoses were polymorphous low-grade adenocarcinoma, adenoid cystic carcinoma, and pleomorphic adenoma.
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Retrospective Studies. Salivary Glands, Minor


71. Kumar K, Gopi A, Thabah MM, Hari S, Safaya R, Gupta R, Sharma SK: Unusual lung mass: benign or malignant? Indian J Chest Dis Allied Sci; 2008 Oct-Dec;50(4):365-7
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  • [Title] Unusual lung mass: benign or malignant?
  • Primary adenoid cystic carcinoma of lung is a rare tumour.
  • Average time that elapses before diagnosis is reported to be two years.
  • We report the case of a patient who remained well inspite of harbouring primary adenoid cystic carcinoma of lung for 15 years.
  • [MeSH-major] Carcinoma, Adenoid Cystic / diagnosis. Lung Neoplasms / diagnosis

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  • (PMID = 19035058.001).
  • [ISSN] 0377-9343
  • [Journal-full-title] The Indian journal of chest diseases & allied sciences
  • [ISO-abbreviation] Indian J Chest Dis Allied Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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72. Palanichamy MG, Zhang YP: Potential pitfalls in MitoChip detected tumor-specific somatic mutations: a call for caution when interpreting patient data. BMC Cancer; 2010;10:597
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  • This study examined mitochondrial sequence variants demonstrated in cancer patients, and assessed the reliability of using detected patterns of polymorphisms in the early diagnosis of cancer.
  • METHODS: Published entire mitochondrial genomes from head and neck, adenoid cystic carcinoma, sessile serrated adenoma, and lung primary tumor from clinical patients were examined in a phylogenetic context and compared with known, naturally occurring mutations which characterize different populations.
  • RESULTS: The phylogenetic linkage analysis of whole arrays of mtDNA mutations from patient cancerous and non-cancerous tissue confirmed that artificial recombination events occurred in studies of head and neck, adenoid cystic carcinoma, sessile serrated adenoma, and lung primary tumor.
  • [MeSH-minor] Adenoma / genetics. Carcinoma, Adenoid Cystic / genetics. Genetic Techniques. Genome. Head and Neck Neoplasms / genetics. Humans. Oligonucleotide Array Sequence Analysis. Phylogeny. Reactive Oxygen Species

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  • (PMID = 21034508.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DNA, Mitochondrial; 0 / Reactive Oxygen Species
  • [Other-IDs] NLM/ PMC2988032
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73. Fu ZC, Zhang B, Fu ZJ: As2O3 may be a treatment option for adenoid cystic carcinoma of salivary gland. Med Hypotheses; 2010 Dec;75(6):490-1
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  • [Title] As2O3 may be a treatment option for adenoid cystic carcinoma of salivary gland.
  • Adenoid cystic carcinoma (ACC) is an uncommon tumor of the head and neck that may occur in any salivary gland tissue.
  • It is a high malignant carcinoma characterized by intensive local invasion and insidious distant metastasis to the lung at an early stage, which is responsible for a poor long-term survival rate.
  • The main clinical treatment to adenoid cystic carcinoma depended on surgical operation in the past.
  • However, it was not so easy to completely excise adenoid cystic carcinoma which resulting in the residual of tumor cells.
  • Adenoid cystic carcinoma is not sensitive to conventional chemotherapeutics, so it is necessary to explore a new kind of drug which possesses inhibition and killing effects to this tumor.
  • A(S2)O(3) may become a treatment option for adenoid cystic carcinoma of salivary gland.
  • [MeSH-major] Apoptosis / drug effects. Arsenicals / therapeutic use. Carcinoma, Adenoid Cystic / drug therapy. Growth Inhibitors / therapeutic use. Oxides / therapeutic use. Salivary Gland Neoplasms / drug therapy

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  • Hazardous Substances Data Bank. ARSENIC TRIOXIDE .
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  • [Copyright] Copyright © 2010 Elsevier Ltd. All rights reserved.
  • (PMID = 20656411.001).
  • [ISSN] 1532-2777
  • [Journal-full-title] Medical hypotheses
  • [ISO-abbreviation] Med. Hypotheses
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Arsenicals; 0 / Growth Inhibitors; 0 / Oxides; S7V92P67HO / arsenic trioxide
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74. Singh A, Ramesh V: Primary cutaneous adenoid cystic carcinoma with distant metastasis: a case report and brief literature review. Indian J Dermatol Venereol Leprol; 2010 Mar-Apr;76(2):176-9
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  • [Title] Primary cutaneous adenoid cystic carcinoma with distant metastasis: a case report and brief literature review.
  • Primary adenoid cystic carcinoma (PCACC) of skin is a rare tumor, and those who show distant metastasis are even rarer.
  • We report a case of PCACC on the face of a 55-year-old man who showed bilateral lung metastasis and on palliative chemotherapy showed significant regression of the primary tumor.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Lung Neoplasms / pathology. Lung Neoplasms / secondary. Skin Neoplasms / pathology

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  • (PMID = 20228549.001).
  • [ISSN] 0973-3922
  • [Journal-full-title] Indian journal of dermatology, venereology and leprology
  • [ISO-abbreviation] Indian J Dermatol Venereol Leprol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] India
  • [Number-of-references] 11
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75. Molina JR, Aubry MC, Lewis JE, Wampfler JA, Williams BA, Midthun DE, Yang P, Cassivi SD: Primary salivary gland-type lung cancer: spectrum of clinical presentation, histopathologic and prognostic factors. Cancer; 2007 Nov 15;110(10):2253-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary salivary gland-type lung cancer: spectrum of clinical presentation, histopathologic and prognostic factors.
  • BACKGROUND: Primary salivary-type lung cancers are rare tumors that include adenoid cystic carcinoma (ACC) and mucoepidermoid carcinoma (MEC).
  • METHODS: In this study, the authors analyzed clinical outcome data from 62 patients who presented with a diagnosis of primary salivary-type lung cancer at the Mayo Clinic (Rochester, Minn) from 1972 to 2002.
  • RESULTS: The median age at diagnosis for patients with MEC was 40 years (range, 6-78 years); and, for patients ACC, the median age at diagnosis was 54 years (range, 21-76 years).
  • Most salivary-type lung cancers presented in the trachea, in the carina, or in a main stem bronchus (70.7%).
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Carcinoma, Mucoepidermoid / pathology. Lung Neoplasms / pathology. Salivary Glands / pathology


76. Kenzaki K, Sakiyama S, Toba H, Nakagawa Y, Takizawa H, Kondo K, Tangoku A: [Clinical analysis of tracheoplasty and bronchoplasty in primary lung cancer]. Kyobu Geka; 2008 Oct;61(11):951-6
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  • [Title] [Clinical analysis of tracheoplasty and bronchoplasty in primary lung cancer].
  • In our department, there were 482 thoracic surgeries for primary lung cancer between 1994 and 2007.
  • The tissue forms were 19 squamous cell carcinomas, 2 adenocarcinomas, 1 large cell carcinoma, 1 adenoid cystic carcinoma and 1 carcinoid, including 2 multiple carcinomas.
  • [MeSH-major] Bronchi / surgery. Lung Neoplasms / surgery. Reconstructive Surgical Procedures / methods. Thoracic Surgical Procedures / methods. Trachea / surgery

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  • (PMID = 18939431.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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77. Locati LD, Guzzo M, Bossi P, Massone PP, Conti B, Fumagalli E, Bareggi C, Cantù G, Licitra L: Lung metastasectomy in adenoid cystic carcinoma (ACC) of salivary gland. Oral Oncol; 2005 Oct;41(9):890-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lung metastasectomy in adenoid cystic carcinoma (ACC) of salivary gland.
  • To define the role of surgical management of lung metastases in ACC.
  • Twenty ACC patients referred to lung metastasectomy were retrospectively reviewed.
  • Lung metastasectomy provided a prolonged FFP in a high selected subset of patients with ACC.
  • [MeSH-major] Carcinoma, Adenoid Cystic / surgery. Lung / surgery. Lung Neoplasms / surgery. Salivary Gland Neoplasms


78. Nuwal P, Dixit R, Singhal AK: Primary adenoid cystic carcinoma of trachea presenting as midline neck swelling and mimicking thyroid tumor: A case report and review of literature. Lung India; 2010 Jul;27(3):167-9
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  • [Title] Primary adenoid cystic carcinoma of trachea presenting as midline neck swelling and mimicking thyroid tumor: A case report and review of literature.
  • We report an extremely rare case of primary adenoid cystic carcinoma (ACC) trachea presenting as midline swelling neck and mimicking thyroid tumor.
  • Fine needle aspiration cytology (FNAC) from swelling reveal features of papillary carcinoma thyroid.
  • Subsequently the operative findings, bronchoscopy and histological diagnosis of excised mass, along with review of FNAC, revealed features of ACC of trachea with exra tracheal extension anteriorly into the soft tissue neck, without actual invasion of the thyroid gland.
  • The cytological differential diagnosis of ACC and CT findings are also briefly discussed.

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  • (PMID = 20931039.001).
  • [ISSN] 0974-598X
  • [Journal-full-title] Lung India : official organ of Indian Chest Society
  • [ISO-abbreviation] Lung India
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2946722
  • [Keywords] NOTNLM ; Adenoid cystic carcinoma trachea / midline swelling neck / thyroid tumor
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79. Sano Y, Kanazawa S, Mimura H, Gobara H, Hiraki T, Fujiwara H, Yamane M, Toyooka S, Oto T, Date H: A novel strategy for treatment of metastatic pulmonary tumors: radiofrequency ablation in conjunction with surgery. J Thorac Oncol; 2008 Mar;3(3):283-8
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  • [Title] A novel strategy for treatment of metastatic pulmonary tumors: radiofrequency ablation in conjunction with surgery.
  • INTRODUCTION: Local treatment that includes surgical resection of metastatic pulmonary tumors is controversial because of the biologic features and invasiveness of these tumors.
  • We report our experience with a premeditated treatment involving combined computed tomography-guided radiofrequency ablation and surgical resection in three patients with metastatic pulmonary tumors.
  • The first was a 67-year-old man with pulmonary metastases of bronchial adenoid cystic carcinoma.
  • We performed partial resection of five tumors in the right lung and ablated a tumor in the left lung.
  • The second was a 66-year-old man with pulmonary metastases of renal cell carcinoma.
  • The third was a 55-year-old man with pulmonary metastases of high-grade sarcoma of the right thigh.
  • We performed partial resection of five tumors in the left lung and ablated a tumor in the right lung.
  • RESULTS: Two patients had metastatic lesions on both sides of the lung; we performed surgical resection on one side and radiofrequency ablation contralaterally to avoid bilateral thoracotomy.
  • CONCLUSIONS: Premeditated treatment involving a combination of radiofrequency ablation and surgical resection can be a useful option in patients with metastatic pulmonary tumors, improving curability and avoiding highly invasive procedures.
  • [MeSH-major] Bronchial Neoplasms / pathology. Carcinoma, Adenoid Cystic / surgery. Carcinoma, Renal Cell / surgery. Catheter Ablation / methods. Kidney Neoplasms / pathology. Lung Neoplasms / surgery. Pneumonectomy / methods
  • [MeSH-minor] Aged. Diagnosis, Differential. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Retrospective Studies. Tomography, X-Ray Computed

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  • (PMID = 18317072.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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80. Huang FH, Tian Z, Zhang CY, Xia RH, Li J: [Effect of DNA methyltransferases 1 inhibition on proliferation, invasion, and metastasis in ACC-M line]. Zhonghua Kou Qiang Yi Xue Za Zhi; 2009 Dec;44(12):745-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To investigate the effect of DNA methyltransferases 1 (DNMT-1) inhibition on the ACC-M cells in vitro and in vivo and discuss the role of DNMT-1 in the development, invasion and metastasis of salivary adenoid cystic carcinoma (SACC).
  • In vivo, the subcutaneous tumor forming rate (6/10), volume [(2.18 +/- 0.83) mm(3)], weight [(0.0156 +/- 0.0046) g] of ACC-M cells was also significantly lower than that of blank [10/10, (155.44 +/- 1.67) mm(3), (0.0724 +/- 0.0157) g], empty load control [10/10, (147.46 +/- 1.73) mm(3), (0.0729 +/- 0.0177) g], P < 0.05, but the rate of lung metastasis was not significantly different among these groups (P > 0.05), and the masses (2.0 +/- 0.5), diameter (70.0 +/- 20.3) microm of ACC-M cells was significantly lower than that of blank [(28.0 +/- 5.5), (195 +/- 25.4) microm], empty load control [(27.0 +/- 4.5), (190.0 +/- 19.9) microm], P < 0.05.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Repressor Proteins / antagonists & inhibitors. Salivary Gland Neoplasms / pathology
  • [MeSH-minor] Animals. Cell Line, Tumor. Humans. Lung Neoplasms / secondary. Mice. Mice, Nude. Neoplasm Invasiveness

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  • (PMID = 20193293.001).
  • [ISSN] 1002-0098
  • [Journal-full-title] Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
  • [ISO-abbreviation] Zhonghua Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / DMAP1 protein, human; 0 / Repressor Proteins
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81. Miettinen M, Lasota J: KIT (CD117): a review on expression in normal and neoplastic tissues, and mutations and their clinicopathologic correlation. Appl Immunohistochem Mol Morphol; 2005 Sep;13(3):205-20
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  • Also, KIT is expressed in pulmonary and other small cell carcinomas, adenoid cystic carcinoma, renal chromophobe carcinoma, thymic, and some ovarian and few breast carcinomas.
  • KIT tyrosine kinase inhibitors such as imatinib mesylate are the generally accepted treatment of metastatic GISTs, and their availability has prompted an active search for other treatment targets among KIT-positive tumors such as myeloid leukemias and small cell carcinoma of the lung, with variable and often nonconvincing results.

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  • (PMID = 16082245.001).
  • [ISSN] 1541-2016
  • [Journal-full-title] Applied immunohistochemistry & molecular morphology : AIMM
  • [ISO-abbreviation] Appl. Immunohistochem. Mol. Morphol.
  • [Language] ENG
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
  • [Number-of-references] 239
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82. Takeda S, Hashimoto T, Kusu T, Kawamura T, Nojiri T, Funakoshi Y, Kadota Y, Maeda H: Management and surgical resection for tracheobronchial tumors institutional experience with 12 patients. Interact Cardiovasc Thorac Surg; 2007 Aug;6(4):484-9
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  • We reviewed the records of 12 patients with primary tracheobronchial tumors and various clinical characteristics treated at our institution to investigate our overall management experience with disease.
  • Over a 21-year period, we treated 1405 cases of primary pulmonary neoplasms, of which 12 (0.9%) patients had primary tracheobronchial tumors with eight different histological types, including three adenoid cystic carcinomas, two bronchial carcinoids, two papillomas, one squamous cell carcinoma, one mucous gland adenoma, one inflammatory pseudotumor, one schwannoma, and one mucoepidermoid carcinoma.
  • A complete resection was performed in ten, which included a sleeve lobectomy in seven, sleeve pneumonectomy in one, tracheal resection in one, and left main stem resection without lung resection in one.
  • [MeSH-major] Bronchial Neoplasms / surgery. Lung Neoplasms / surgery. Tracheal Neoplasms / surgery

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  • (PMID = 17669912.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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83. Satake N, Yoshida S, Jinnouchi O, Sekita T: Adenoid cystic carcinoma of maxillary sinus with metastatic hepatocellular carcinoma. Case report. APMIS; 2005 Jun;113(6):450-5
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  • [Title] Adenoid cystic carcinoma of maxillary sinus with metastatic hepatocellular carcinoma. Case report.
  • A case of collision tumor in the left maxillary sinus composed of adenoid cystic carcinoma (ACC) and metastatic hepatocellular carcinoma (HCC) is reported.
  • Radiographic examination revealed masses in the liver and bilateral lung metastases.
  • For this reason, differential diagnosis between a second primary tumor and metastasis was made.
  • The metastatic lesion immunohistochemically showed positivity for hepatocyte antigen (OCH1E5) and protein induced by vitamin K absence or antagonist II (PIVKA-II), sustaining the HCC diagnosis.
  • Primary ACC and metastatic HCC in the maxillary sinus are rare, and this may therefore be the first case of maxillary sinus tumor with both these elements.
  • [MeSH-major] Carcinoma, Adenoid Cystic / diagnosis. Carcinoma, Hepatocellular / secondary. Liver Neoplasms / pathology. Maxillary Sinus Neoplasms / diagnosis. Maxillary Sinus Neoplasms / secondary. Neoplasms, Multiple Primary / diagnosis
  • [MeSH-minor] Antigens, Neoplasm / analysis. Diagnosis, Differential. Hepatocytes / immunology. Humans. Liver / radiography. Lung / radiography. Male. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 15996162.001).
  • [ISSN] 0903-4641
  • [Journal-full-title] APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
  • [ISO-abbreviation] APMIS
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, Neoplasm
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84. Till BG, Martins RG: Response to paclitaxel in adenoid cystic carcinoma of the salivary glands. Head Neck; 2008 Jun;30(6):810-4
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  • [Title] Response to paclitaxel in adenoid cystic carcinoma of the salivary glands.
  • BACKGROUND: Paclitaxel is not considered to be an active drug in adenoid cystic carcinoma (ACC) of the salivary glands.
  • (1) a 58-year-old man with recurrent ACC who developed pulmonary metastases, had progressive disease after a good response to first-line chemotherapy, and then achieved a partial response to weekly single- agent paclitaxel; and (2) a 46-year-old woman with extensive thoracic ACC metastases who achieved a significant response after 2 cycles of paclitaxel chemotherapy.
  • [MeSH-major] Antineoplastic Agents, Phytogenic / therapeutic use. Carcinoma, Adenoid Cystic / drug therapy. Lung Neoplasms / drug therapy. Paclitaxel / therapeutic use. Salivary Gland Neoplasms / drug therapy

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  • (PMID = 17979110.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; P88XT4IS4D / Paclitaxel
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85. Whatley WS, Thompson JW, Rao B: Salivary gland tumors in survivors of childhood cancer. Otolaryngol Head Neck Surg; 2006 Mar;134(3):385-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The most common second malignancies are acute leukemia, bone and soft tissue tumors, and carcinoma of the skin, breast, and thyroid.
  • The pathology of the salivary gland tumors were mucoepidermoid carcinoma (10), adenoid cystic carcinoma (1) , and pleomorphic adenoma (1).
  • All patients were treated with surgical excision of the primary tumor, and postoperative radiation was added in select patients.
  • Eleven patients were alive with no evidence of disease at last follow-up, and 1 patient was alive with clinical evidence of pulmonary metastasis.
  • The majority of these neoplasms are malignant; mucoepidermoid carcinoma occurs most frequently.
  • The treatment of these tumors includes surgical excision of the primary, with neck dissection in patients with clinical evidence of nodal metastasis, and postoperative radiation added for pathologies with adverse features.
  • [MeSH-major] Neoplasms, Second Primary / diagnosis. Salivary Gland Neoplasms / diagnosis. Survivors
  • [MeSH-minor] Adenoma, Pleomorphic / diagnosis. Adenoma, Pleomorphic / surgery. Carcinoma, Adenoid Cystic / diagnosis. Carcinoma, Adenoid Cystic / surgery. Carcinoma, Mucoepidermoid / diagnosis. Carcinoma, Mucoepidermoid / surgery. Child. Disease-Free Survival. Female. Follow-Up Studies. Humans. Lung Neoplasms / secondary. Lymphatic Metastasis / diagnosis. Male. Neck Dissection. Neoplasms / drug therapy. Neoplasms / radiotherapy. Radiotherapy, Adjuvant. Registries. Retrospective Studies. Risk Factors


86. Hemminki K, Chen B: Parental lung cancer as predictor of cancer risks in offspring: clues about multiple routes of harmful influence? Int J Cancer; 2006 Feb 1;118(3):744-8
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  • [Title] Parental lung cancer as predictor of cancer risks in offspring: clues about multiple routes of harmful influence?
  • We examined whether 0-70-year-old offspring of parents with lung cancer are at a risk of cancer that cannot be explained by their smoking or familial risk.
  • Among offspring of affected mothers, increased risks were observed for upper aerodigestive (SIR 1.45), nasal (2.93), lung (1.71) and bladder (1.52) cancers and for kidney cancer (6.41) in one age group.
  • The risk of bladder cancer was found in younger age groups than that of lung cancer.
  • Nasal cancer was even increased when either parent was diagnosed with lung cancer; the highest risk was for nasal adenoid cystic carcinoma (7.73).
  • [MeSH-major] Genetic Predisposition to Disease. Lung Neoplasms / genetics. Parents

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  • [Copyright] Copyright 2005 Wiley-Liss, Inc.
  • (PMID = 16094627.001).
  • [ISSN] 0020-7136
  • [Journal-full-title] International journal of cancer
  • [ISO-abbreviation] Int. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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87. Bobbio A, Copelli C, Ampollini L, Bianchi B, Carbognani P, Bettati S, Sesenna E, Rusca M: Lung metastasis resection of adenoid cystic carcinoma of salivary glands. Eur J Cardiothorac Surg; 2008 May;33(5):790-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lung metastasis resection of adenoid cystic carcinoma of salivary glands.
  • BACKGROUND: Adenoid cystic carcinoma is a rare tumour originating from the exocrine mucous glands, known for its high propensity for distant metastases.
  • The value of lung metastasis resection from adenoid cystic carcinoma of salivary glands origin is evaluated.
  • METHODS: A retrospective study was conducted on patients undergoing surgery for primary adenoid cystic carcinoma of the salivary glands between 1982 and 2006.
  • Patients were excluded who had primary tumour macroscopic incomplete resection or were lost at follow-up.
  • Nine patients who presented isolated lung recurrence underwent complete lung metastasectomy.
  • RESULTS: Twenty-six men and 24 women with a median age of 57 years (range 33-79) underwent radical surgery for adenoid cystic carcinoma during the study period.
  • Nine patients with a median free interval time of 5 years (range 1-12) underwent lung metastasectomy: five had single metastasis resection, one multiple mono-pulmonary and three multiple and bilateral.
  • In six of these patients a new disease recurrence was noted: four patients underwent further lung metastasectomy, but in all of them progression of the disease was observed.
  • CONCLUSIONS: Patients with adenoid cystic carcinoma could be frequently encountered with disease recurrence confined to the lung.
  • The impact of complete lung metastasis resection on the course of the disease, however, is yet to be determined.
  • [MeSH-major] Lung Neoplasms / secondary. Lung Neoplasms / surgery. Neoplasm Recurrence, Local / surgery. Salivary Gland Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Carcinoma, Adenoid Cystic / mortality. Carcinoma, Adenoid Cystic / secondary. Carcinoma, Adenoid Cystic / surgery. Disease-Free Survival. Female. Follow-Up Studies. Humans. Kaplan-Meier Estimate. Linear Models. Male. Middle Aged. Retrospective Studies. Survival Rate

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  • (PMID = 18343149.001).
  • [ISSN] 1010-7940
  • [Journal-full-title] European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • [ISO-abbreviation] Eur J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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88. Ali TZ, Epstein JI: Basal cell carcinoma of the prostate: a clinicopathologic study of 29 cases. Am J Surg Pathol; 2007 May;31(5):697-705
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  • [Title] Basal cell carcinoma of the prostate: a clinicopathologic study of 29 cases.
  • We studied 29 cases of basal cell carcinoma of the prostate including what others call adenoid cystic carcinoma of the prostate.
  • The most common methods of diagnosis was transurethral resection (TURP) (n=29) and needle biopsy (n=9).
  • In 28/29 cases, slides were reviewed and 24 (86%) cases showed more than 1 pattern: adenoid cysticlike (AC-P) pattern and small solid nests with peripheral palisading were the most predominant patterns, each seen in 18 cases (64%).
  • Metastases developed in 4/29 patients: 1 in lung, 1 in lung and liver, 1 in lung, bone and liver, 1 in penile urethra.
  • [MeSH-major] Carcinoma, Basal Cell / pathology. Prostatic Neoplasms / pathology

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  • (PMID = 17460452.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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89. Macarenco RS, Uphoff TS, Gilmer HF, Jenkins RB, Thibodeau SN, Lewis JE, Molina JR, Yang P, Aubry MC: Salivary gland-type lung carcinomas: an EGFR immunohistochemical, molecular genetic, and mutational analysis study. Mod Pathol; 2008 Sep;21(9):1168-75
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  • [Title] Salivary gland-type lung carcinomas: an EGFR immunohistochemical, molecular genetic, and mutational analysis study.
  • Salivary gland-type lung carcinomas are uncommon neoplasms of the lung, the two most common being adenoid cystic carcinoma and mucoepidermoid carcinoma.
  • Although they usually have an indolent behavior, adenoid cystic carcinomas can be more aggressive, with 5-year survival as low as 55%.
  • In contrast to the most common subtypes of lung carcinomas, epidermal growth factor receptor studies have not been carried out in this group of tumors.
  • Herein we report a series of 24 cases (12 adenoid cystic and 12 mucoepidermoid carcinomas) tested for epidermal growth factor receptor protein expression, epidermal growth factor receptor gene copy gains, and epidermal growth factor receptor gene mutational status, through immunohistochemistry, fluorescence in situ hybridization, and sequencing of the exons 18-21, respectively.
  • Overall, 91 and 92% of the adenoid cystic carcinomas and mucoepidermoid carcinomas expressed epidermal growth factor receptor protein.
  • Chromosome 7 polysomy occurred in 25% of the cases (four adenoid cystic carcinomas and two mucoepidermoid carcinomas).
  • Immunoexpression of epidermal growth factor receptor in salivary gland-type lung carcinomas is not related to epidermal growth factor receptor gene copy number or mutational status.

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  • (PMID = 18587327.001).
  • [ISSN] 1530-0285
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA090628-08; United States / NCI NIH HHS / CA / K12 CA090628; United States / NCI NIH HHS / CA / K12 CA090628-08
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Neoplasm; EC 2.7.10.1 / EGFR protein, human; EC 2.7.10.1 / Receptor, Epidermal Growth Factor
  • [Other-IDs] NLM/ NIHMS121772; NLM/ PMC2752817
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90. Sato K, Ueda Y, Sakurai A, Ishikawa Y, Kaji S, Nojima T, Katsuda S: Adenoid cystic carcinoma of the maxillary sinus with gradual histologic transformation to high-grade adenocarcinoma: a comparative report with dedifferentiated carcinoma. Virchows Arch; 2006 Feb;448(2):204-8
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  • [Title] Adenoid cystic carcinoma of the maxillary sinus with gradual histologic transformation to high-grade adenocarcinoma: a comparative report with dedifferentiated carcinoma.
  • We report a unique case of adenoid cystic carcinoma (ACC) of the maxillary sinus, with gradual histologic transformation from lower-grade ACC (cribriform and tubular types) to high-grade adenocarcinoma (HGA) showing a sequential histologic spectrum via solid-type ACC.
  • The tumor was discriminated from a dedifferentiated carcinoma or hybrid tumor.
  • Autopsy specimens also demonstrated both solid-type ACC and HGA components in the lung and spleen.
  • [MeSH-major] Adenocarcinoma / pathology. Carcinoma, Adenoid Cystic / pathology. Maxillary Sinus Neoplasms / pathology
  • [MeSH-minor] Actins / analysis. Aged. Carcinoma / metabolism. Carcinoma / pathology. Disease Progression. Fatal Outcome. Humans. Immunohistochemistry. Keratins / analysis. Liver Neoplasms / secondary. Lung Neoplasms / secondary. Male. Muscle, Smooth / chemistry. S100 Proteins / analysis. Tumor Suppressor Protein p53 / analysis


91. Yokouchi H, Otsuka Y, Otoguro Y, Takemoto N, Ito K, Uchida Y, Okamoto K, Nishimura M, Kimura K, Kaji H: Primary peripheral adenoid cystic carcinoma of the lung and literature comparison of features. Intern Med; 2007;46(21):1799-803
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  • [Title] Primary peripheral adenoid cystic carcinoma of the lung and literature comparison of features.
  • Adenoid cystic carcinoma arising from the peripheral lung is rare.
  • Here, we describe adenoid cystic carcinoma that developed in the peripherally in S(9) of the right lower lobe of an 84-year-old woman.
  • [MeSH-major] Carcinoma, Adenoid Cystic / diagnosis. Lung Neoplasms / diagnosis

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  • (PMID = 17978538.001).
  • [ISSN] 1349-7235
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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92. Lin WY, Hsu WH: Tumor-to-tumor metastasis: maxillary sinus adenoid cystic carcinoma metastasizing to double primary lung adenocarcinoma. Ann Thorac Surg; 2010 Oct;90(4):e59-61
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  • [Title] Tumor-to-tumor metastasis: maxillary sinus adenoid cystic carcinoma metastasizing to double primary lung adenocarcinoma.
  • The most frequent metastatic donor is lung cancer, and the most frequent recipient is renal cell carcinoma.
  • Here we present a patient in whom lung cancer served as a metastatic recipient and maxillary sinus adenoid cystic carcinoma acted as a metastatic donor.
  • This patient has double primary lung cancer, which increased the complexity of this case.
  • [MeSH-major] Adenocarcinoma / pathology. Carcinoma, Adenoid Cystic / secondary. Lung Neoplasms / pathology. Maxillary Sinus Neoplasms / pathology

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  • [Copyright] Copyright © 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20868783.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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93. Park YW, Kim SG, Choi JY, Lee SK: Recapitulating orthotopic tumor model through establishment of a parotid gland tumor with lung metastasis using HeLa cell injection into nude mice. Oncol Rep; 2010 Mar;23(3):701-8
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  • [Title] Recapitulating orthotopic tumor model through establishment of a parotid gland tumor with lung metastasis using HeLa cell injection into nude mice.
  • HeLa cells showed significantly higher lung metastatic potential in the parotid gland than in the subcutis.
  • [MeSH-major] Lung Neoplasms / secondary. Parotid Neoplasms / pathology
  • [MeSH-minor] Animals. Carcinoma, Adenoid Cystic / blood supply. Carcinoma, Adenoid Cystic / pathology. Epidermal Growth Factor / pharmacology. Fibroblast Growth Factor 2 / analysis. HeLa Cells. Humans. Male. Mice. Mice, Nude. Neoplasm Transplantation. Receptor, Epidermal Growth Factor / metabolism. Transplantation, Heterologous. Xenograft Model Antitumor Assays

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  • (PMID = 20127009.001).
  • [ISSN] 1791-2431
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 103107-01-3 / Fibroblast Growth Factor 2; 62229-50-9 / Epidermal Growth Factor; EC 2.7.10.1 / Receptor, Epidermal Growth Factor
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94. Chen F, Sonobe M, Sato K, Fujinaga T, Shoji T, Sakai H, Miyahara R, Bando T, Okubo K, Hirata T, Date H: Pulmonary resection for metastatic head and neck cancer. World J Surg; 2008 Aug;32(8):1657-62
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pulmonary resection for metastatic head and neck cancer.
  • BACKGROUND: Pulmonary metastasectomy has become the standard therapy for various metastatic malignancies to the lungs; however, little data have been available about lung metastasectomy for head and neck cancers.
  • To confirm a role for resection of pulmonary metastases for such tumors, we reviewed our institutional experience.
  • METHODS: Between 1991 and 2007, 20 patients with pulmonary metastases from head and neck cancers underwent complete pulmonary resection.
  • All patients had obtained or had obtainable locoregional control of their primary head and neck cancers.
  • RESULTS: Of the 20 patients, 10 (50%) had squamous cell carcinoma, 7 (35%) had adenoid cystic carcinoma, and 3 had miscellaneous carcinomas.
  • The median disease-free interval from the time of treatment of the head and neck primary cancers to the development of pulmonary metastases was 27 months.
  • Disease-free survival rate was 25.0% at 5 years after pulmonary resection.
  • Patients with squamous cell carcinoma and male sex showed a worse overall survival (p = 0.04 and 0.03, respectively).
  • CONCLUSION: The current practice of pulmonary metastasectomy for head and neck cancers in our institution was well justified.
  • A disease-free interval equal to or longer than 12 months, nonsquamous cell carcinoma, and female sex might be relevant to a better prognosis.
  • [MeSH-major] Adenocarcinoma / secondary. Adenocarcinoma / surgery. Carcinoma, Squamous Cell / secondary. Carcinoma, Squamous Cell / surgery. Head and Neck Neoplasms / pathology. Lung Neoplasms / secondary. Lung Neoplasms / surgery

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  • (PMID = 18553194.001).
  • [ISSN] 0364-2313
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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95. Lin CH, Yen RF, Jeng YM, Tzen CY, Hsu C, Hong RL: Unexpected rapid progression of metastatic adenoid cystic carcinoma during treatment with imatinib mesylate. Head Neck; 2005 Dec;27(12):1022-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unexpected rapid progression of metastatic adenoid cystic carcinoma during treatment with imatinib mesylate.
  • BACKGROUND: There is a lack of effective treatment for metastatic adenoid cystic carcinoma (ACC), a usually indolent tumor.
  • METHOD: Five patients with lung metastasis were treated in a pilot study with imatinib 400 mg by mouth twice a day.
  • [MeSH-major] Antineoplastic Agents / adverse effects. Carcinoma, Adenoid Cystic / drug therapy. Head and Neck Neoplasms / pathology. Lung Neoplasms / drug therapy. Piperazines / adverse effects. Pyrimidines / adverse effects

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  • [Copyright] (c) 2005 Wiley Periodicals, Inc.
  • (PMID = 16265655.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Benzamides; 0 / Piperazines; 0 / Pyrimidines; 8A1O1M485B / Imatinib Mesylate; EC 2.7.10.1 / Protein-Tyrosine Kinases
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96. Elkin AD, Jacobs CD: Tamoxifen for salivary gland adenoid cystic carcinoma: report of two cases. J Cancer Res Clin Oncol; 2008 Oct;134(10):1151-3
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  • [Title] Tamoxifen for salivary gland adenoid cystic carcinoma: report of two cases.
  • PURPOSE: Adenoid cystic carcinoma of the salivary gland (ACC-SG) is a slow-growing tumor that is refractory to most chemotherapeutic agents.
  • [MeSH-major] Antineoplastic Agents, Hormonal / therapeutic use. Carcinoma, Adenoid Cystic / drug therapy. Salivary Gland Neoplasms / drug therapy. Tamoxifen / therapeutic use
  • [MeSH-minor] Adult. Combined Modality Therapy. Female. Humans. Lung Neoplasms / drug therapy. Lung Neoplasms / secondary. Neoplasm Recurrence, Local / drug therapy. Toremifene / therapeutic use

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  • (PMID = 18347813.001).
  • [ISSN] 0171-5216
  • [Journal-full-title] Journal of cancer research and clinical oncology
  • [ISO-abbreviation] J. Cancer Res. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Hormonal; 094ZI81Y45 / Tamoxifen; 7NFE54O27T / Toremifene
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97. Caiado A, Moura e Sá J: [Tracheal tumors review--a clinical case of adenoid cystic carcinoma]. Rev Port Pneumol; 2008 Jul-Aug;14(4):527-34
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Tracheal tumors review--a clinical case of adenoid cystic carcinoma].
  • [Transliterated title] Revisão dos tumores da traqueia--a propósito de um caso clínico de tumor adenóide cístico.
  • Their incidence is less than 0.2 per 100 000 inhabitants and 180 times less frequent than lung cancer.
  • The authors report a case of adenoid cystic carcinoma in a 23 year-old woman, non-smoker, with acute clinical inspiratory stridor, where Nd-Yag laser use was extremely important to tracheal permeability as the tumor occupied over 80% of the tracheal lumen and could have led to imminent patient asphyxia.
  • [MeSH-major] Carcinoma, Adenoid Cystic. Tracheal Neoplasms

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  • (PMID = 18622529.001).
  • [ISSN] 0873-2159
  • [Journal-full-title] Revista portuguesa de pneumologia
  • [ISO-abbreviation] Rev Port Pneumol
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Portugal
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98. Davies AM, Ho C, Metzger AS, Beckett LA, Christensen S, Tanaka M, Lara PN, Lau DH, Gandara DR: Phase I study of two different schedules of bortezomib and pemetrexed in advanced solid tumors with emphasis on non-small cell lung cancer. J Thorac Oncol; 2007 Dec;2(12):1112-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Phase I study of two different schedules of bortezomib and pemetrexed in advanced solid tumors with emphasis on non-small cell lung cancer.
  • Tumor types included lung (n = 16), adenoid cystic carcinoma (n = 2), prostate (n = 2), sarcoma (n = 2), breast (n = 1), thymus (n = 1), head and neck (n = 1), and gastrointestinal(n = 2).
  • Of the 16 patients with non-small cell lung cancer, 2 (12.5%) had partial response and 9 had stable disease, for a disease control rate of 68.8%.
  • Based on the observed efficacy, a phase II study in non-small cell lung cancer is warranted.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Carcinoma, Non-Small-Cell Lung / drug therapy. Carcinoma, Non-Small-Cell Lung / mortality. Lung Neoplasms / drug therapy. Lung Neoplasms / mortality

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  • (PMID = 18090584.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Boronic Acids; 0 / Glutamates; 0 / Pyrazines; 04Q9AIZ7NO / Pemetrexed; 5Z93L87A1R / Guanine; 69G8BD63PP / Bortezomib
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99. Daneshbod Y, Modjtahedi E, Atefi S, Bedayat GR, Daneshbod K: Exfoliative cytologic findings of primary pulmonary adenoid cystic carcinom: a report of 2 cases with a review of the cytologic features. Acta Cytol; 2007 Jul-Aug;51(4):558-62
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Exfoliative cytologic findings of primary pulmonary adenoid cystic carcinom: a report of 2 cases with a review of the cytologic features.
  • BACKGROUND: Adenoid cystic carcinoma is a very rare primary pulmonary neoplasm.
  • Cytologic findings of pulmonary washing and brushing in 2 cases of primary bronchial adenoid cystic carcinoma with special histologic features are described, with an emphasis on some points that have not been reported previously, together with the diagnostic pitfalls.
  • CASES: Two cases of primary adenoid cystic carcinoma of the lung were diagnosed on exfoliative cytology.
  • In case 2, chondromyxoid material and a bimorphic population of tumor cells caused diagnostic confusion with other salivary gland-type tumors of the lung.
  • CONCLUSION: These cases showed characteristic cytologic findings of adenoid cystic carcinoma together with rare findings of intracellular and extracellular inclusionlike bodies, myxochondroid material, bimorphic populations and nuclear molding, which can cause diagnostic confusion with other lung tumors.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Lung Neoplasms / pathology

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  • (PMID = 17718121.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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100. Roviaro G, Vergani C, Maciocco M, Varoli F, Francese M, Despini L: Tracheal sleeve pneumonectomy: long-term outcome. Lung Cancer; 2006 Apr;52(1):105-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Selected primary lung cancers less than 2cm from the carina or invading the tracheo-bronchial angle, formerly considered inoperable, can be amenable to tracheal sleeve pneumonectomy (TSP).
  • Since 1993 in every patient with lung cancer we perform a thoracoscopic exploration as the first step of the intervention.
  • TSP is the only concrete option for treating lung cancer originating less than 2 cm from the carina.
  • [MeSH-major] Lung Neoplasms / surgery. Pneumonectomy. Tracheal Neoplasms / surgery
  • [MeSH-minor] Adenocarcinoma / surgery. Carcinoma, Adenoid Cystic / surgery. Carcinoma, Large Cell / surgery. Carcinoma, Squamous Cell / surgery. Humans. Pleural Neoplasms / secondary. Pleural Neoplasms / surgery. Prognosis. Survival Rate. Thoracotomy. Trachea

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  • (PMID = 16481067.001).
  • [ISSN] 0169-5002
  • [Journal-full-title] Lung cancer (Amsterdam, Netherlands)
  • [ISO-abbreviation] Lung Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
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