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1. Boitte JP, Traoré J, Boukhet F, Mondié JM, Traoré M, Delbosc B: [Adenoid cystic carcinoma of the lacrimal gland in a 14-year-old girl]. J Fr Ophtalmol; 2006 Oct;29(8):937-40
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  • [Title] [Adenoid cystic carcinoma of the lacrimal gland in a 14-year-old girl].
  • [Transliterated title] Carcinome adénoïde kystique de la glande lacrymale chez une enfant âgée de 14 ans.
  • The diagnosis was cylindroma, or adenoid cystic carcinoma.
  • Cylindromas or adenoid cystic carcinomas of the lachrymal gland are the second most common cause of epithelial tumors in this gland, which are characterized by a high degree of malignancy, a very high rate of recurrence, and a low survival rate at 5 years.
  • [MeSH-major] Carcinoma, Adenoid Cystic. Eye Neoplasms. Lacrimal Apparatus

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  • (PMID = 17075512.001).
  • [ISSN] 1773-0597
  • [Journal-full-title] Journal français d'ophtalmologie
  • [ISO-abbreviation] J Fr Ophtalmol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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2. Tse DT: Clinical and microdissection genotyping analyses of the effect of intra-arterial cytoreductive chemotherapy in the treatment of lacrimal gland adenoid cystic carcinoma. Trans Am Ophthalmol Soc; 2005;103:337-67
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  • [Title] Clinical and microdissection genotyping analyses of the effect of intra-arterial cytoreductive chemotherapy in the treatment of lacrimal gland adenoid cystic carcinoma.
  • PURPOSE: To determine the effect of intra-arterial cytoreductive chemotherapy (IACC) as an adjunct of a multimodality protocol for the treatment of lacrimal gland adenoid cystic carcinoma (ACC).
  • Nine consecutive patients with lacrimal gland ACC were treated with IACC, followed by orbital exenteration and chemoradiotherapy.
  • RESULTS: The carcinoma cause-specific death rates between the two treatment groups was significant (P = .029, log-rank test).
  • The cumulative 5-year carcinoma cause-specific death rate was 16.7% in the IACC-treated group compared with 57.1% in the conventional treatment group.
  • CONCLUSIONS: The preliminary data suggest that IACC as an integral component of a multimodal treatment strategy is potentially effective in improving local disease control and overall disease-free survival in lacrimal gland ACC.

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  • (PMID = 17057810.001).
  • [ISSN] 1545-6110
  • [Journal-full-title] Transactions of the American Ophthalmological Society
  • [ISO-abbreviation] Trans Am Ophthalmol Soc
  • [Language] ENG
  • [Grant] United States / NEI NIH HHS / EY / P30 EY014801; United States / NEI NIH HHS / EY / P30-EY014801
  • [Publication-type] Case Reports; Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  • [Other-IDs] NLM/ PMC1447581
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3. Kawamata T, Harashima S, Kubo O, Hori T: Intrasellar remote metastasis from adenoid cystic carcinoma of parotid gland: case report. Endocr J; 2006 Oct;53(5):659-63
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  • [Title] Intrasellar remote metastasis from adenoid cystic carcinoma of parotid gland: case report.
  • Adenoid cystic carcinoma is a tumor of exocrine glands originating primarily from the minor and major salivary glands, lacrimal gland, bronchus, breast, and intestinal and genital tracts.
  • Intracranial remote metastasis from adenoid cystic carcinoma in salivary gland is quite rare.
  • The authors encountered a case of intrasellar remote metastasis from an adenoid cystic carcinoma of parotid gland origin, presenting with hyponatremia secondary to the syndrome of inappropriate secretion of antidiuretic hormone (SIADH).
  • To our knowledge, this is the first reported case of metastasis from an adenoid cystic carcinoma to intrasellar area.
  • A 78-year-old woman had an adenoid cystic carcinoma in the left parotid gland, which was resected surgically followed by local radiation therapy of 60 Gy.
  • Histopathological examination of the tumor specimens revealed adenoid cystic carcinoma, which had identical histological findings as those of the painful superficial cervical lymph nodes resected in the same operation.
  • Although rare, metastasis from tumors including those of salivary gland origin should be considered in the differential diagnosis of unusual pituitary tumors.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Parotid Neoplasms / pathology. Pituitary Neoplasms / secondary. Sella Turcica

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  • (PMID = 16902261.001).
  • [ISSN] 0918-8959
  • [Journal-full-title] Endocrine journal
  • [ISO-abbreviation] Endocr. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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4. Lee JI, Kim YZ, Lee EH, Kim KH: Skull base invasion of adenoid cystic carcinoma of the lacrimal gland : a case report. J Korean Neurosurg Soc; 2008 Oct;44(4):273-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Skull base invasion of adenoid cystic carcinoma of the lacrimal gland : a case report.
  • Although adenoid cystic carcinoma (ACC) of the lacrimal gland is a rarely encountered orbital tumor, it invades intracranially more frequently than carcinomas of other glands in the head and neck.
  • The authors report a case of skull base invasion by an ACC of the lacrimal gland to remind neurosurgeons planning intervention that this disease shows a tendency to invade intracranially.

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  • (PMID = 19096692.001).
  • [ISSN] 2005-3711
  • [Journal-full-title] Journal of Korean Neurosurgical Society
  • [ISO-abbreviation] J Korean Neurosurg Soc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2588318
  • [Keywords] NOTNLM ; Adenoid cystic carcinoma / Metastasis / Prognosis / Skull base
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5. Esmaeli B, Golio D, Kies M, DeMonte F: Surgical management of locally advanced adenoid cystic carcinoma of the lacrimal gland. Ophthal Plast Reconstr Surg; 2006 Sep-Oct;22(5):366-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical management of locally advanced adenoid cystic carcinoma of the lacrimal gland.
  • PURPOSE: To review our experience with multidisciplinary surgical management of locally advanced adenoid cystic carcinoma of the lacrimal gland.
  • METHODS: We present a case series of 7 patients with lacrimal gland adenoid cystic carcinoma treated at our institution between June 2001 and October 2003.
  • RESULTS: The study included 3 men and 4 women (mean age at diagnosis, 44 years).
  • CONCLUSIONS: Orbitectomy with bone removal may be indicated for achieving local and regional control in advanced cases of adenoid cystic carcinoma of the lacrimal gland.
  • [MeSH-major] Carcinoma, Adenoid Cystic / surgery. Eye Neoplasms / surgery. Lacrimal Apparatus. Orbit Evisceration / methods

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  • (PMID = 16985421.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article
  • [Publication-country] United States
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6. Arsene D, Ardeleanu C, Dănăilă L: Skull base tumor invading both cavernous sinuses. Adenoid cystic carcinoma mimicking a meningioma. Rom J Morphol Embryol; 2006;47(4):367-71
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  • [Title] Skull base tumor invading both cavernous sinuses. Adenoid cystic carcinoma mimicking a meningioma.
  • However, the orbital portion of the tumor, which was surgically removed, proved to be an adenoid cystic carcinoma.
  • Some peculiar immunohistochemical findings were obvious, as well as a lack of continuity of the tumor with the local lacrimal gland.
  • This is an unusual situation, when a lacrimal gland tumor spread along the cavernous sinus, cross the midline and approaches the contralateral orbit.
  • Such local extension should be considered in the differential diagnosis of anterior skull base tumors.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Cavernous Sinus / pathology. Meningioma / pathology. Skull Base Neoplasms / pathology

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  • (PMID = 17392985.001).
  • [ISSN] 1220-0522
  • [Journal-full-title] Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
  • [ISO-abbreviation] Rom J Morphol Embryol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Romania
  • [Chemical-registry-number] 0 / Antigens, CD44; 0 / Cadherins; 0 / Vimentin; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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7. Ahmad SM, Esmaeli B, Williams M, Nguyen J, Fay A, Woog J, Selvadurai D, Rootman J, Weis E, Selva D, McNab A, DeAngelis D, Calle A, Lopez A: American Joint Committee on Cancer classification predicts outcome of patients with lacrimal gland adenoid cystic carcinoma. Ophthalmology; 2009 Jun;116(6):1210-5
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  • [Title] American Joint Committee on Cancer classification predicts outcome of patients with lacrimal gland adenoid cystic carcinoma.
  • PURPOSE: To investigate whether American Joint Committee on Cancer (AJCC) classification at initial diagnosis of lacrimal gland adenoid cystic carcinoma predicts outcome of treatment on local recurrence.
  • PARTICIPANTS: Consecutive patients with adenoid cystic carcinoma of the lacrimal gland treated at 8 institutions between January 1986 and December 2007.
  • RESULTS: AJCC classification at initial diagnosis was assessable for 53 patients and was as follows: T1N0M0, 7 patients; T2N0M0, 8 patients; T3aN0M0, 14 patients; T3aNxM0, 1 patient; T3aN0M1, 1 patient; T3bN0M0, 13 patients; T3bN0M1, 1 patient; T4aN0M0, 2 patients; T4bN0M0, 4 patients; T4bN0M1, 1 patient; and T4bNXM0, 1 patient.
  • CONCLUSIONS: In patients with lacrimal gland adenoid cystic carcinoma, AJCC >T3 disease at initial diagnosis correlates with worse outcomes than does AJCC <T3 disease.
  • [MeSH-major] Carcinoma, Adenoid Cystic / classification. Eye Neoplasms / classification. Lacrimal Apparatus Diseases / classification. Neoplasm Recurrence, Local / diagnosis

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  • [CommentIn] Ophthalmology. 2010 Jan;117(1):196 [20114119.001]
  • (PMID = 19395039.001).
  • [ISSN] 1549-4713
  • [Journal-full-title] Ophthalmology
  • [ISO-abbreviation] Ophthalmology
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
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8. Hajda M, Korányi K, Salomváry B, Bajcsay A: [Clinical presentation, differential diagnosis and treatment of lacrimal gland tumours]. Magy Onkol; 2005;49(1):65-70
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  • [Title] [Clinical presentation, differential diagnosis and treatment of lacrimal gland tumours].
  • PURPOSE: We describe the tumours occurring in the lacrimal gland fossa region, the important symptoms and the principles of the therapy.
  • RESULTS: Space-occupying lesions of lacrimal gland fossa are: 1.
  • Epithelial lacrimal gland tumours, which may be benign or malignant (benign pleomorphic adenoma, malignant pleomorphic adenocarcinoma, adenoid cystic carcinoma, other carcinomas).
  • In our Institute, 42% of the tumours of the lacrimal fossa was epithelial, 50% was lymphoid or pseudotumour, and 8% other tumours.
  • Of the 59 primary epithelial tumours 62.7% was benign and 37.3% was malignant.
  • The differential diagnosis and management are based on the clinical presentations, imaging studies and histological examination.
  • CONCLUSIONS: Pleomorphic adenomas of the lacrimal gland should be diagnosed on radiological and clinical evidence, and biopsy avoided to prevent the recurrences and malignant transformation.
  • The prognosis of pleomorphic adenomas depends on the early diagnosis and radical surgical excision of the lesion.
  • In cases of suspected malignant epithelial tumours, lymphomas and pseudotumours, biopsy is indicated for the choice of appropriate treatment.
  • [MeSH-major] Eye Neoplasms / diagnosis. Eye Neoplasms / therapy. Lacrimal Apparatus. Orbital Diseases / diagnosis. Orbital Diseases / therapy
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / therapy. Adenoma / diagnosis. Adenoma / therapy. Cystadenocarcinoma / diagnosis. Cystadenocarcinoma / therapy. Diagnosis, Differential. Granuloma / diagnosis. Granuloma / therapy. Hodgkin Disease / diagnosis. Hodgkin Disease / therapy. Humans. Leukemia / diagnosis. Leukemia / therapy. Lymphoma / diagnosis. Lymphoma / therapy. Lymphoma, Non-Hodgkin / diagnosis. Lymphoma, Non-Hodgkin / therapy. Orbital Pseudotumor / diagnosis. Orbital Pseudotumor / therapy. Plasmacytoma / diagnosis. Plasmacytoma / therapy. Prognosis. Retrospective Studies. Sarcoidosis / diagnosis. Sarcoidosis / therapy. Treatment Outcome

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  • (PMID = 15902337.001).
  • [ISSN] 0025-0244
  • [Journal-full-title] Magyar onkologia
  • [ISO-abbreviation] Magy Onkol
  • [Language] hun
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Hungary
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9. Tse DT, Benedetto P, Morcos JJ, Johnson TE, Weed D, Dubovy S: An atypical presentation of adenoid cystic carcinoma of the lacrimal gland. Am J Ophthalmol; 2006 Jan;141(1):187-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An atypical presentation of adenoid cystic carcinoma of the lacrimal gland.
  • PURPOSE: To report a case of lacrimal gland adenoid cystic carcinoma (ACC) with an atypical initial presentation and to postulate an anatomical explanation for this unusual biologic behavior.
  • The left lacrimal gland and the contiguous bone appeared normal.
  • ACC tumor cells were identified in nerve fiber bundles surrounding and within the lacrimal gland.
  • CONCLUSIONS: In patients presenting with an infiltrative mass in the cavernous sinus or orbital apex, metastatic disease from an occult lacrimal gland primary should be considered, even with a normal-appearing lacrimal gland.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Eye Neoplasms / pathology. Lacrimal Apparatus Diseases / pathology. Orbital Neoplasms / pathology. Paranasal Sinus Neoplasms / pathology

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  • (PMID = 16386996.001).
  • [ISSN] 0002-9394
  • [Journal-full-title] American journal of ophthalmology
  • [ISO-abbreviation] Am. J. Ophthalmol.
  • [Language] eng
  • [Grant] United States / NEI NIH HHS / EY / P30 EY 014801
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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10. Williams MD, Al-Zubidi N, Debnam JM, Shinder R, DeMonte F, Esmaeli B: Bone invasion by adenoid cystic carcinoma of the lacrimal gland: preoperative imaging assessment and surgical considerations. Ophthal Plast Reconstr Surg; 2010 Nov-Dec;26(6):403-8
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  • [Title] Bone invasion by adenoid cystic carcinoma of the lacrimal gland: preoperative imaging assessment and surgical considerations.
  • PURPOSE: To identify the incidence of radiologically and histologically documented bony invasion of the lacrimal gland fossa by adenoid cystic carcinoma.
  • PATIENTS AND METHODS: The authors reviewed the records of all 18 patients with lacrimal gland adenoid cystic carcinoma surgically treated at their institution from 1997 to 2009 for imaging findings (blinded review) and histologic findings on evaluation of the lacrimal gland fossa.
  • Preoperative imaging suggested bony involvement of the lacrimal gland fossa in 13 patients (76.5%); this was histologically confirmed in 11 of the 13.
  • Overall, 14 of 17 histologically evaluable cases (82.3%) had invasion of the lacrimal gland fossa.
  • CONCLUSIONS: Adenoid cystic carcinoma of the lacrimal gland is associated with bone invasion in essentially all but the smallest of tumors (T1).
  • This high rate of bone involvement may warrant addressing the bony walls during surgery for adenoid cystic carcinoma of the lacrimal gland.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Eye Neoplasms / pathology. Lacrimal Apparatus Diseases / pathology. Nasal Bone / pathology. Nose Neoplasms / pathology


11. Paarlberg JC, den Hollander JC, Hafezi F, Paridaens D: [Adenoid cystic carcinoma of the upper eyelid]. Ophthalmologe; 2007 Dec;104(12):1066-7
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  • [Title] [Adenoid cystic carcinoma of the upper eyelid].
  • [Transliterated title] Adenoid-zystisches Karzinom des Oberlids.
  • Adenoid cystic carcinoma (ACC) is a rare epithelial malignancy, which tends to grow slowly.
  • ACC most commonly arises in the lacrimal gland.
  • Very rarely, ACC originates from accessory lacrimal gland tissue.
  • Its origin most likely is an accessory lacrimal gland.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Carcinoma, Adenoid Cystic / surgery. Chalazion / diagnosis. Eyelid Neoplasms / pathology. Eyelid Neoplasms / surgery
  • [MeSH-minor] Diagnosis, Differential. Diagnostic Errors. Humans. Male. Middle Aged. Treatment Outcome

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  • (PMID = 17447072.001).
  • [ISSN] 0941-293X
  • [Journal-full-title] Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
  • [ISO-abbreviation] Ophthalmologe
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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12. Tirakunwichcha S, Tulvatana W: Disappearance of primitive basaloid cells after external irradiation in adenoid cystic carcinoma of the lacrimal gland. J Med Assoc Thai; 2006 Aug;89(8):1318-21
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  • [Title] Disappearance of primitive basaloid cells after external irradiation in adenoid cystic carcinoma of the lacrimal gland.
  • OBJECTIVE: To study the histopathological findings of basaloid adenoid cystic carcinoma after high dose orbital irradiation.
  • MATERIAL AND METHOD: The histopathology study was done in a 38-year-old Thai female patient who had basaloid adenoid cystic carcinoma of the right lacrimal gland confirmed by incisional biopsy.
  • After a 60-Gy external irradiation, the mass decreased in size and finally could not be palpated, but subsequent orbital imaging still showed infiltrative soft tissue mass at the right lacrimal gland with bony defects at posterosuperior and lateral walls without extraorbital extension.
  • RESULTS: Microscopic examination revealed periglandular infiltration with chronic inflammation of the palpebral lobe of lacrimal gland.
  • There was only a small area of cribiform pattern of the adenoid cystic carcinoma left; no basaloid pattern was seen in the tissue.
  • CONCLUSION: The primitive cells (basaloid pattern) disappear after orbital irradiation for adenoid cystic carcinoma of the lacrimal gland.
  • [MeSH-major] Basophils / radiation effects. Carcinoma, Adenoid Cystic / pathology. Lacrimal Apparatus / radiation effects. Lacrimal Apparatus / surgery. Lacrimal Apparatus Diseases / pathology. Orbital Neoplasms / radiotherapy

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  • (PMID = 17048448.001).
  • [ISSN] 0125-2208
  • [Journal-full-title] Journal of the Medical Association of Thailand = Chotmaihet thangphaet
  • [ISO-abbreviation] J Med Assoc Thai
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Thailand
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13. Tse DT, Benedetto P, Dubovy S, Schiffman JC, Feuer WJ: Clinical analysis of the effect of intraarterial cytoreductive chemotherapy in the treatment of lacrimal gland adenoid cystic carcinoma. Am J Ophthalmol; 2006 Jan;141(1):44-53
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  • [Title] Clinical analysis of the effect of intraarterial cytoreductive chemotherapy in the treatment of lacrimal gland adenoid cystic carcinoma.
  • PURPOSE: To determine the effect of intraarterial cytoreductive chemotherapy (IACC) as an adjunct to conventional surgery and radiation therapy for lacrimal gland adenoid cystic carcinoma (ACC).
  • METHODS: setting: Institutional. patient population: Nine consecutive patients with lacrimal gland ACC were treated with IACC, followed by orbital exenteration and chemoradiotherapy.
  • RESULTS: The difference between the carcinoma cause-specific death rate of the study group versus conventional treatment was significant (P = .029, log rank test).
  • The cumulative 5-year carcinoma cause-specific death rate in the IACC treated group was 16.7% compared with 57.1% in the conventional treatment group.
  • CONCLUSIONS: The preliminary data suggest that IACC as an integral component of a multimodal treatment strategy is potentially effective in improving local disease control and overall disease-free survival in lacrimal gland adenoid cystic carcinoma.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Carcinoma, Adenoid Cystic / drug therapy. Eye Neoplasms / drug therapy. Lacrimal Apparatus Diseases / drug therapy

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  • [CommentIn] Can J Ophthalmol. 2013 Apr;48(2):e17-8 [23561610.001]
  • (PMID = 16386975.001).
  • [ISSN] 0002-9394
  • [Journal-full-title] American journal of ophthalmology
  • [ISO-abbreviation] Am. J. Ophthalmol.
  • [Language] eng
  • [Grant] United States / NEI NIH HHS / EY / P30 EY 014801
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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14. Tse DT, Finkelstein SD, Benedetto P, Dubovy S, Schiffman J, Feuer WJ: Microdissection genotyping analysis of the effect of intraarterial cytoreductive chemotherapy in the treatment of lacrimal gland adenoid cystic carcinoma. Am J Ophthalmol; 2006 Jan;141(1):54-61
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  • [Title] Microdissection genotyping analysis of the effect of intraarterial cytoreductive chemotherapy in the treatment of lacrimal gland adenoid cystic carcinoma.
  • PURPOSE: To investigate the feasibility of integrating molecular analysis into standard histopathology for lacrimal gland adenoid cystic carcinoma (ACC), and to gain insights into the molecular pathogenesis of this tumor and its response to intraarterial cytoreductive chemotherapy (IACC) that is of clinical use.
  • METHODS: setting: Institutional. patient population: Nine consecutive patients with lacrimal gland ACC were treated with IACC, followed by orbital exenteration and chemoradiotherapy.
  • CONCLUSIONS: Microdissection genotyping holds promise as a clinical tool in integrating molecular analysis into standard histopathology to advance the understanding of lacrimal gland ACC tumorigenesis.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Carcinoma, Adenoid Cystic / genetics. Chromosomes, Human, Pair 1 / genetics. Eye Neoplasms / genetics. Lacrimal Apparatus Diseases / genetics. Loss of Heterozygosity. Microsatellite Repeats / genetics

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  • (PMID = 16386976.001).
  • [ISSN] 0002-9394
  • [Journal-full-title] American journal of ophthalmology
  • [ISO-abbreviation] Am. J. Ophthalmol.
  • [Language] eng
  • [Grant] United States / NEI NIH HHS / EY / P30 EY 014801
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Neoplasm; 0 / Neoplasm Proteins
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15. Lin SC, Kau HC, Yang CF, Yang MH, Tsai CC, Kao SC, Hsu WM: Adenoid cystic carcinoma arising in the inferior orbit without evidence of lacrimal gland involvement. Ophthal Plast Reconstr Surg; 2008 Jan-Feb;24(1):74-6
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  • [Title] Adenoid cystic carcinoma arising in the inferior orbit without evidence of lacrimal gland involvement.
  • Incisional biopsy revealed an adenoid cystic carcinoma.
  • The lacrimal gland was uninvolved by tumor microscopically.
  • Although rare, adenoid cystic carcinoma must be considered in the differential diagnosis of an orbital tumor, because the unusual location of an orbital adenoid cystic carcinoma may make its early detection difficult.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Orbital Neoplasms / pathology

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  • (PMID = 18209657.001).
  • [ISSN] 0740-9303
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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16. You JQ, Wang P: [Protein expression of p53, bcl-2, and bax in adenoid cystic carcinoma of lacrimal gland]. Zhonghua Yi Xue Za Zhi; 2008 Jul 22;88(28):1978-82
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  • [Title] [Protein expression of p53, bcl-2, and bax in adenoid cystic carcinoma of lacrimal gland].
  • OBJECTIVE: To investigate the expression of p53, bcl-2, and hax, apoptosis regulating genes, in adenoid cystic carcinoma of larcrimal gland and the roles thereof in clinical prognosis.
  • METHODS: 56 patients of adenoid cystic carcinoma of larcrimal gland were divided into two groups according to the prognosis: poor prognosis group with recurrence or metastasis within 5 years (n=32) and better prognosis group (n=24) surviving tumor free within 5 years.
  • 8 cases of normal lacrimal gland tissues were used as controls. RESULTS:.
  • (1) The overall positive rate of p53 of the patients with adenoid cystic carcinoma of larcrimal gland was 73.2%, significantly higher than that of the normal controls (0, P < 0.05).
  • The protein expression of p53 in adenoid cystic carcinoma of larcrimal gland was negatively correlated with clinical prognosis. (2) The overall expression rate of bcl-2 of the patients with adenoid cystic carcinoma of larcrimal gland was 69.6%, significantly lower than that of the control group (P < 0.05).
  • The expression bcl-2 protein was correlated with better clinical prognosis. (3) The bax positive rate of the patients with adenoid cystic carcinoma of larcrimal gland group was 60.7%, not significantly lower than the control group.
  • CONCLUSION: Some apoptosis regulating genes, such as mutation-type (mt) p53 play an important role in the gene ration and development of adenoid cystic carcinoma of larcrimal gland. p53, bax, and bcl-2 proteins may act as valuable signals for clinical prognosis.
  • [MeSH-major] Carcinoma, Adenoid Cystic / metabolism. Lacrimal Apparatus / metabolism. Proto-Oncogene Proteins c-bcl-2 / biosynthesis. Tumor Suppressor Protein p53 / biosynthesis. bcl-2-Associated X Protein / biosynthesis

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  • (PMID = 19062739.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Proto-Oncogene Proteins c-bcl-2; 0 / Tumor Suppressor Protein p53; 0 / bcl-2-Associated X Protein
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17. Goto H, Yamamoto T, Ishiyama Z, Usui M, Okada S: Adenoid cystic carcinoma arising from the lower eyelid. Jpn J Ophthalmol; 2006 Jul-Aug;50(4):374-6
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  • [Title] Adenoid cystic carcinoma arising from the lower eyelid.
  • BACKGROUND: Primary cutaneous adenoid cystic carcinoma is one of the rarest eyelid tumors.
  • CASE: A 39-year-old man presented with a small subcutaneous induration in his left lower eyelid close to the lower lacrimal punctum.
  • OBSERVATIONS: Under a clinical diagnosis of chalazion, the eyelid induration was extracted surgically via the palpebral conjunctiva.
  • Histopathological examination of the extracted tumor revealed proliferation of basaloid cells with a prominent cribriform pattern containing Alcian blue-positive and periodic acid Schiff-positive material, leading to a diagnosis of adenoid cystic carcinoma.
  • The patient subsequently underwent extended radical excision including the lacrimal sac.
  • CONCLUSIONS: Adenoid cystic carcinoma should be considered as a differential diagnosis of eyelid tumors simulating chalazion.
  • Adenoid cystic carcinoma in the eyelid may have a more favorable prognosis than that in the lacrimal gland.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Eyelid Neoplasms / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Follow-Up Studies. Humans. Male. Ophthalmologic Surgical Procedures

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  • [Copyright] Copyright (c) Japanese Ophthalmological Society 2006.
  • (PMID = 16897224.001).
  • [ISSN] 0021-5155
  • [Journal-full-title] Japanese journal of ophthalmology
  • [ISO-abbreviation] Jpn. J. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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18. Liao Y, Zeng H, Wang X, Huang Y, Chen N, Ge B, Tang L, Luo Q: Expression patterns and prognostic significance of inhibitor of apoptosis proteins in adenoid cystic carcinoma and pleomorphic adenoma of lachrymal gland. Exp Eye Res; 2009 Jan;88(1):4-11
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  • [Title] Expression patterns and prognostic significance of inhibitor of apoptosis proteins in adenoid cystic carcinoma and pleomorphic adenoma of lachrymal gland.
  • Adenoid cystic carcinoma (ACC) of lachrymal gland is a malignant tumor with a poor prognosis, while, pleomorphic adenoma (PA) is the benign tumor of lachrymal gland epithelia.
  • Livin expression was almost undetectable in both malignancy and benign lesion of lachrymal gland.
  • Overexpression of Survivin in ACC was associated with poorer survival, which may have clinical impact on diagnosis and therapeutic considerations of this malignancy.
  • [MeSH-major] Adenoma, Pleomorphic / metabolism. Biomarkers, Tumor / metabolism. Carcinoma, Adenoid Cystic / metabolism. Inhibitor of Apoptosis Proteins / metabolism. Lacrimal Apparatus Diseases / metabolism

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  • (PMID = 18955046.001).
  • [ISSN] 1096-0007
  • [Journal-full-title] Experimental eye research
  • [ISO-abbreviation] Exp. Eye Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Inhibitor of Apoptosis Proteins; 0 / Neoplasm Proteins; 0 / RNA, Messenger
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19. Bernardini FP, Devoto MH, Croxatto JO: Epithelial tumors of the lacrimal gland: an update. Curr Opin Ophthalmol; 2008 Sep;19(5):409-13
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  • [Title] Epithelial tumors of the lacrimal gland: an update.
  • PURPOSE OF REVIEW: The goal of this article is to offer an update on the treatment and prognosis of the most common epithelial tumors of the lacrimal gland, report on new pathological entities and offer a review of the classification of lacrimal gland tumors.
  • RECENT FINDINGS: Improvements have been made in the understanding of lacrimal gland lesions with the knowledge that lacrimal gland tumors compare to the more common counterparts of the major salivary glands.
  • Therefore, the WHO's classification of salivary gland tumors has been adapted to the lacrimal gland pathology.
  • Until recently, primary adenocarcinomas of the lacrimal gland were not further subclassified, but they can now be divided into low-grade and high-grade malignancies.
  • The adjunctive use of intra-arterial cytoreductive chemotherapy for the management of adenoid cystic carcinoma is one of the most important advancements on the management of these aggressive tumors.
  • Another important step forward has been taken on carcinoma ex pleomorphic adenoma of the lacrimal gland, which is subclassified into noninvasive carcinoma, with an excellent prognosis after complete excision and invasive carcinoma for which the prognosis is still guarded despite adjunctive radiotherapy.
  • SUMMARY: This article offers an update on diagnosis, classification and treatment of common and rare epithelial lacrimal gland tumors.
  • [MeSH-major] Eye Neoplasms / pathology. Lacrimal Apparatus Diseases / pathology. Neoplasms, Glandular and Epithelial / pathology

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  • (PMID = 18772674.001).
  • [ISSN] 1531-7021
  • [Journal-full-title] Current opinion in ophthalmology
  • [ISO-abbreviation] Curr Opin Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 31
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20. Prabhakaran VC, Cannon PS, McNab A, Davis G, O'Donnell B, Dolman PJ, Ghabrial R, Selva D: Lesions mimicking lacrimal gland pleomorphic adenoma. Br J Ophthalmol; 2010 Nov;94(11):1509-12
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  • [Title] Lesions mimicking lacrimal gland pleomorphic adenoma.
  • AIM: To report a series of patients with lacrimal gland lesions simulating the clinicoradiological features of lacrimal gland pleomorphic adenoma (LGPA).
  • The diagnosis of LGPA was made in all cases by experienced orbital surgeons, based on clinicoradiological features, and lacrimal gland excision was performed.
  • Postoperative histology revealed lymphoma (four patients), chronic dacryoadenitis (three patients), adenoid cystic carcinoma (two patients), Sjogren's syndrome (two patients), cavernous haemangioma (one patient), benign lymphoid hyperplasia (one patient) and granulomatous dacryoadenitis (one patient).
  • The accepted clinicoradiological criteria used for the diagnosis of LGPA have a high false-positive rate, even in experienced hands.
  • Based on this study, the authors believe that fine-needle aspiration biopsy or intraoperative biopsy and frozen section diagnosis may help reduce unnecessary lacrimal gland excision.
  • [MeSH-major] Adenoma, Pleomorphic / diagnosis. Eye Neoplasms / diagnosis. Lacrimal Apparatus Diseases / diagnosis
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 20962353.001).
  • [ISSN] 1468-2079
  • [Journal-full-title] The British journal of ophthalmology
  • [ISO-abbreviation] Br J Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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21. Santos RR, Damasceno RW, de Pontes FS, Cursino SR, Nishiwaki-Dantas MC, Vital Filho J, Dantas PE: Ten-year follow-up of a case series of primary epithelial neoplasms of the lacrimal gland: clinical features, surgical treatment and histopathological findings. Arq Bras Oftalmol; 2010 Jan-Feb;73(1):33-9
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  • [Title] Ten-year follow-up of a case series of primary epithelial neoplasms of the lacrimal gland: clinical features, surgical treatment and histopathological findings.
  • PURPOSE: To describe and analyze the features of a cases series of patients with primary epithelial neoplasms of the lacrimal gland, its surgical treatment, and histopathological findings.
  • METHODS: Retrospective evaluation of files from patients with primary epithelial neoplasms of the lacrimal gland in the period from 1997 to 2007.
  • All patients with primary epithelial tumors of the lacrimal gland were included in this study.
  • RESULTS: During the study period, there were 12 patients, 5 (41.7%) with benign tumors, all pleomorphic adenomas (benign mixed tumor) and 7 (58.3%) with malignant neoplasms, thus distributed: four cases of adenoid cystic carcinoma, two of mucoepidermoid carcinoma and one carcinoma expleomorphic adenoma.
  • Globally, patients mean age was 54.1 years-old (ranging from 14 to 70 years-old), with mean age of 52.4 years-old (ranging from 14 to 65 years-old) for benign neoplasms, and 55.3 years-old for malignant neoplasms (ranging from 26 to 70 years-old).
  • CONCLUSIONS: The most frequent primary epithelial neoplasms of the lacrimal gland were pleomorphic adenoma and adenoid cystic carcinoma during the study period.
  • Malignant tumors were more frequent than benign tumors.
  • The histopathological diagnosis and the disease initial stage can play a significant role in patient's survival.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Carcinoma, Adenoid Cystic / pathology. Carcinoma, Mucoepidermoid / pathology. Lacrimal Apparatus / pathology. Lacrimal Apparatus Diseases / pathology

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  • (PMID = 20464111.001).
  • [ISSN] 1678-2925
  • [Journal-full-title] Arquivos brasileiros de oftalmologia
  • [ISO-abbreviation] Arq Bras Oftalmol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
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22. Zeidan BA, Abu Hilal M, Al-Gholmy M, El-Mahallawi H, Pearce NW, Primrose JN: Adenoid Cystic Carcinoma of the lacrimal gland metastasising to the liver: report of a case. World J Surg Oncol; 2006;4:66
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  • [Title] Adenoid Cystic Carcinoma of the lacrimal gland metastasising to the liver: report of a case.
  • BACKGROUND: Adenoid Cystic Carcinoma of the lacrimal gland is a rare tumour.
  • CASE PRESENTATION: We report a rare case of an isolated liver metastasis from a lacrimal gland adenoid cystic carcinoma 20 years after resection of the primary tumour.
  • The histology revealed a predominantly cribriform tumour with focal areas of basaloid type metastatic lacrimal gland adenoid cystic carcinoma.
  • CONCLUSION: This case illustrates the unpredictable behaviour of adenoid cystic carcinoma and the need for a life long follow up for these patients after treatment.
  • The possibility of surgical resection for liver metastasis from adenoid cystic carcinoma should always be considered.

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  • (PMID = 16987423.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1592487
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23. Vaidhyanath R, Kirke R, Brown L, Sampath R: Lacrimal fossa lesions: pictorial review of CT and MRI features. Orbit; 2008;27(6):410-8
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  • [Title] Lacrimal fossa lesions: pictorial review of CT and MRI features.
  • A wide range of disease process involve the lacrimal gland/fossa.
  • In this pictorial review, we use histology-proven cases to illustrate conditions that affect the lacrimal gland/fossa.
  • [MeSH-major] Eye Neoplasms / diagnosis. Lacrimal Apparatus Diseases / diagnosis. Magnetic Resonance Imaging. Tomography, X-Ray Computed
  • [MeSH-minor] Adenoma, Pleomorphic / diagnosis. Carcinoma, Adenoid Cystic / diagnosis. Carcinoma, Squamous Cell / diagnosis. Dacryocystitis / diagnosis. Dermoid Cyst / diagnosis. Granulomatosis with Polyangiitis / diagnosis. Humans. Lymphoproliferative Disorders / diagnosis. Sarcoidosis / diagnosis. Sjogren's Syndrome / diagnosis

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  • (PMID = 19085295.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 27
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24. Lacrimal Gland Tumor Study Group: An epidemiological survey of lacrimal fossa lesions in Japan: number of patients and their sex ratio by pathological diagnosis. Jpn J Ophthalmol; 2005 Sep-Oct;49(5):343-8
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  • [Title] An epidemiological survey of lacrimal fossa lesions in Japan: number of patients and their sex ratio by pathological diagnosis.
  • PURPOSE: To report the results of a survey conducted on lacrimal fossa lesions in Japan.
  • METHODS: The subjects were patients with lacrimal fossa lesions pathologically diagnosed between January 1995 and December 1997.
  • We sent survey questionnaires to 1201 hospitals with training facilities accredited by the Japanese Ophthalmological Society and determined the number of patients and their sex ratio by pathological diagnosis.
  • RESULTS: Among tumors with high frequency, there were 86 cases of pleomorphic adenoma and 19 cases of adenoid cystic carcinoma in the category of epithelial tumor; 55 cases of malignant lymphoma and 32 cases of reactive lymphoid hyperplasia in the category of nonepithelial tumor; and 50 cases of inflammation and 22 cases of cystic lesion in the category of nonneoplastic lesion.
  • CONCLUSIONS: The sex ratio by pathological diagnosis revealed that women had a higher rate than men of pleomorphic adenoma, whereas men had a higher rate than women of malignant epithelial tumor.
  • [MeSH-major] Eye Neoplasms / epidemiology. Lacrimal Apparatus Diseases / epidemiology

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  • (PMID = 16187032.001).
  • [ISSN] 0021-5155
  • [Journal-full-title] Japanese journal of ophthalmology
  • [ISO-abbreviation] Jpn. J. Ophthalmol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
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25. Ben Simon GJ, Schwarcz RM, Douglas R, Fiaschetti D, McCann JD, Goldberg RA: Orbital exenteration: one size does not fit all. Am J Ophthalmol; 2005 Jan;139(1):11-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Diagnosis included orbital, ocular, and adnexal malignancies, with squamous and basal cell carcinoma being the most common.
  • CONCLUSIONS: Clinical indications for orbital exenteration remain similar over the last four decades with a higher prevalence of squamous cell carcinoma in our institute.
  • Orbital exenteration is considered curative in cases of basal or squamous cell carcinoma but not in cases of malignant infiltrative processes such as adenoid cystic carcinoma of the lacrimal gland.

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  • [CommentIn] Am J Ophthalmol. 2005 Jan;139(1):152-3 [15652840.001]
  • (PMID = 15652823.001).
  • [ISSN] 0002-9394
  • [Journal-full-title] American journal of ophthalmology
  • [ISO-abbreviation] Am. J. Ophthalmol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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26. Bonanno A, Esmaeli B, Fingeret MC, Nelson DV, Weber RS: Social challenges of cancer patients with orbitofacial disfigurement. Ophthal Plast Reconstr Surg; 2010 Jan-Feb;26(1):18-22
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  • Three patients had adenoid cystic carcinoma of lacrimal gland, 3 had squamous cell carcinoma of conjunctiva/eyelid, and 1 each had conjunctival melanoma, eyelid sebaceous gland carcinoma, transitional cell carcinoma of lacrimal sac, adenocarcinoma of orbit, neuroendocrine carcinoma of orbit, and basal cell carcinoma of eyelid.

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  • (PMID = 20090478.001).
  • [ISSN] 1537-2677
  • [Journal-full-title] Ophthalmic plastic and reconstructive surgery
  • [ISO-abbreviation] Ophthal Plast Reconstr Surg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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27. Esson MD, Blanco-Guzman M, Douglas PS: Delayed tension pneumocephalus complicating orbital exenteration. Br J Oral Maxillofac Surg; 2005 Apr;43(2):123-5
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  • A 43-year-old woman with a recurrent adenoid cystic carcinoma of the lacrimal gland was treated by orbital exenteration and reconstruction.
  • [MeSH-major] Carcinoma, Adenoid Cystic / surgery. Eye Neoplasms / surgery. Lacrimal Apparatus Diseases / surgery. Orbit Evisceration / adverse effects. Pneumocephalus / etiology

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  • (PMID = 15749212.001).
  • [ISSN] 0266-4356
  • [Journal-full-title] The British journal of oral & maxillofacial surgery
  • [ISO-abbreviation] Br J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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28. Kim MS, Park K, Kim JH, Kim YD, Lee JI: Gamma knife radiosurgery for orbital tumors. Clin Neurol Neurosurg; 2008 Dec;110(10):1003-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PATIENTS AND METHODS: Fifteen patients with orbital tumors (7 meningiomas, 3 cavernous hemangiomas, 2 schwannomas, 2 metastatic tumors and 1 adenoid cystic carcinoma of the lacrimal gland) were treated.
  • Three patients with malignant lesions had to undergo another operation due to tumor progression.

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  • (PMID = 18653273.001).
  • [ISSN] 0303-8467
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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29. Zwahlen RA, Grätz KW, Obwegeser JA: The galea fascia flap in orbital reconstruction: innovative harvest technique. Eur J Surg Oncol; 2006 Sep;32(7):804-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • AIM: To report the treatment of a recurrent adenoid-cystic carcinoma of the lacrimal gland required orbital exenteration with an en bloc resection of the lateral orbital rim and wall and an anterior portion of the temporal muscle.
  • [MeSH-minor] Carcinoma, Adenoid Cystic / surgery. Eye Neoplasms / surgery. Fascia. Female. Humans. Lacrimal Apparatus Diseases / surgery. Middle Aged

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  • (PMID = 16765557.001).
  • [ISSN] 0748-7983
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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30. Siddaraju N, Solo S, Soundararaghavan J, Srinivasan R: Fine needle aspiration biopsy of pleomorphic adenoma and adenoid cystic carcinoma of the lacrimal gland. Acta Cytol; 2008 Jul-Aug;52(4):515-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fine needle aspiration biopsy of pleomorphic adenoma and adenoid cystic carcinoma of the lacrimal gland.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Carcinoma, Adenoid Cystic / pathology. Eye Neoplasms / pathology. Lacrimal Apparatus / pathology
  • [MeSH-minor] Adult. Biopsy, Fine-Needle. Diagnosis, Differential. Female. Humans

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  • (PMID = 18702379.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
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31. Sonmez G, Haholu A, Mutlu H, Ozturk E, Sildiroglu O, Bilgi O, Basekim C, Kizilkaya E: Medical image. A case of adenoid cystic carcinoma of the lacrimal gland: MRI findings. N Z Med J; 2007;120(1258):U2638
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  • [Title] Medical image. A case of adenoid cystic carcinoma of the lacrimal gland: MRI findings.
  • [MeSH-major] Carcinoma, Adenoid Cystic / diagnosis. Eye Neoplasms / diagnosis
  • [MeSH-minor] Adult. Female. Humans. Lacrimal Apparatus / pathology. Magnetic Resonance Imaging

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  • (PMID = 17653256.001).
  • [ISSN] 1175-8716
  • [Journal-full-title] The New Zealand medical journal
  • [ISO-abbreviation] N. Z. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] New Zealand
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32. Meel R, Pushker N, Bakhshi S: Adjuvant chemotherapy in lacrimal gland adenoid cystic carcinoma. Pediatr Blood Cancer; 2009 Dec;53(6):1163-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adjuvant chemotherapy in lacrimal gland adenoid cystic carcinoma.
  • [MeSH-major] Carcinoma, Adenoid Cystic / drug therapy. Lacrimal Apparatus Diseases / drug therapy

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  • (PMID = 19743515.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
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