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43. Pelosi G, Rodriguez J, Viale G, Rosai J: Salivary gland-type tumors with myoepithelial differentiation arising in pulmonary hamartoma: report of 2 cases of a hitherto unrecognized association. Am J Surg Pathol; 2006 Mar;30(3):375-87
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Salivary gland-type tumors with myoepithelial differentiation arising in pulmonary hamartoma: report of 2 cases of a hitherto unrecognized association.
  • Reported is a hitherto unrecognized association of pulmonary hamartomas with salivary gland-type tumors showing myoepithelial differentiation, namely, a case of myoepithelioma arising in a otherwise classic hamartoma with cartilage predominance, and a case of malignant mixed tumor arising in a predominantly fibrous hamartoma resembling müllerian adenofibroma.
  • The myoepithelioma patient was well with no signs of recurrent disease at 6-month clinical control, but she was then lost to follow-up; the malignant mixed tumor patient is alive and well after 6 months since operation.
  • Both tumors presented with morphologic and immunohistochemical features of myoepithelial cells, and we interpret them as being derived from a myoepithelial-like stromal cell population found within the hamartomatous areas, which is also consistently detected in classic pulmonary hamartoma.
  • The lack of individual cell necrosis, mitotic activity, cell atypia, and pulmonary parenchyma infiltration supported a diagnosis of benign or unproven malignant potential tumor for the myoepithelioma, whereas the reverse held true for the other tumor in which the diagnosis of malignant mixed tumor of the lung was rendered.
  • [MeSH-major] Hamartoma / pathology. Lung Neoplasms / pathology. Mixed Tumor, Malignant / pathology. Myoepithelioma / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor. Biopsy, Needle. Cell Transformation, Neoplastic. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Lung Diseases / metabolism. Lung Diseases / pathology. Lung Diseases / surgery. Salivary Glands / pathology

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  • (PMID = 16538059.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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4. Yamamoto S, Tsuda H, Suzuki K, Takano M, Tamai S, Matsubara O: An allelotype analysis indicating the presence of two distinct ovarian clear-cell carcinogenic pathways: endometriosis-associated pathway vs. clear-cell adenofibroma-associated pathway. Virchows Arch; 2009 Sep;455(3):261-70
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  • [Title] An allelotype analysis indicating the presence of two distinct ovarian clear-cell carcinogenic pathways: endometriosis-associated pathway vs. clear-cell adenofibroma-associated pathway.
  • Patterns of allele loss (loss of heterozygosity (LOH)) were studied to identify the genetic backgrounds underlying the two putative carcinogenic pathways of ovarian clear-cell adenocarcinoma: carcinomas thought to arise in endometriosis (endometriosis-associated carcinomas, 20 cases) and carcinomas thought to be derived from clear-cell adenofibroma ((CCAF)-associated carcinomas, 14 cases).
  • Each tumor was assessed for LOH at 24 polymorphic loci located on 12 chromosomal arms: 1p, 3p, 5q, 8p, 9p, 10q, 11q, 13q, 17p, 17q, 19p, and 22q.
  • [MeSH-major] Adenocarcinoma, Clear Cell / etiology. Adenocarcinoma, Clear Cell / genetics. Adenofibroma / complications. Endometriosis / complications. Loss of Heterozygosity. Ovarian Neoplasms / genetics
  • [MeSH-minor] Alleles. Female. Humans. Hypoxia-Inducible Factor 1, alpha Subunit / analysis. Immunohistochemistry. Von Hippel-Lindau Tumor Suppressor Protein / analysis

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  • (PMID = 19655165.001).
  • [ISSN] 1432-2307
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / HIF1A protein, human; 0 / Hypoxia-Inducible Factor 1, alpha Subunit; EC 2.3.2.27 / Von Hippel-Lindau Tumor Suppressor Protein; EC 6.3.2.- / VHL protein, human
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47. Subhawong TK, Subhawong AP, Hamper UM: Serous adenofibroma of the testicle: case report and review of the literature. J Ultrasound Med; 2010 Jan;29(1):135-9
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  • [Title] Serous adenofibroma of the testicle: case report and review of the literature.
  • [MeSH-major] Adenofibroma / surgery. Adenofibroma / ultrasonography. Orchiectomy. Testicular Neoplasms / surgery. Testicular Neoplasms / ultrasonography

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  • (PMID = 20040787.001).
  • [ISSN] 1550-9613
  • [Journal-full-title] Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
  • [ISO-abbreviation] J Ultrasound Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 14
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48. D'Angelo E, Prat J: Uterine sarcomas: a review. Gynecol Oncol; 2010 Jan;116(1):131-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Their histopathologic classification was revised by the World Health Organization (WHO) in 2003.
  • A new staging system has been recently designed by the International Federation of Gynecology and Obstetrics (FIGO).
  • RESULTS: Since carcinosarcomas (malignant mixed mesodermal tumors or MMMT) are currently classified as metaplastic carcinomas, leiomyosarcomas remain the most common uterine sarcomas.
  • Adenofibromas may represent well-differentiated adenosarcomas.
  • Immunohistochemical studies of oncoproteins as well as molecular analysis of non-random translocations will undoubtedly lead to an accurate and prognostically relevant classification of these rare tumors.

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  • (PMID = 19853898.001).
  • [ISSN] 1095-6859
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 74
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53. Shatova OP, Borzenko BG, Zinkovich II, Sedakov IE: [Lactate dehydrogenase, adenosine deaminase and thymidine phosphorylase activity of blood and tissues in breast cancer]. Ukr Biokhim Zh (1999); 2009 Jul-Aug;81(4):88-93
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  • Lactate dehydrogenase (LDH), adenosine deaminase and thymidine phosphorylase activity was analyzed in the blood serum, primary tumor and adjacent uninvolved breast tissues from 49 women with adenocarcinoma and from 10 ones with benign adenofibroma.
  • Serum LDH level reflects cell membrane alterations not only in the tumor node cells but also to a greater extent--in the surrounding unmalignant tissues.

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  • (PMID = 20387638.001).
  • [Journal-full-title] Ukraïnsʹkyĭ biokhimichnyĭ z︠h︡urnal (1999 )
  • [ISO-abbreviation] Ukr Biokhim Zh (1999)
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Ukraine
  • [Chemical-registry-number] EC 1.1.1.27 / L-Lactate Dehydrogenase; EC 2.4.2.4 / TYMP protein, human; EC 2.4.2.4 / Thymidine Phosphorylase; EC 3.5.4.4 / ADA protein, human; EC 3.5.4.4 / Adenosine Deaminase
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54. Wani Y, Notohara K: Ovarian clear cell carcinoma arising in a mucinous cystadenoma. Int J Gynecol Pathol; 2009 Nov;28(6):584-8
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  • The clear cell components had adenofibroma-like features devoid of significant nuclear atypia or stromal invasion, including distinctive foci of CC with a hobnail appearance and hyperchromatic nuclei surrounded by desmoplastic or hyalinized stroma.

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  • (PMID = 19851211.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, Estrogen
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