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61. He HB, Tang XF, Li LJ, Li L, Hua CG: [Effect of mechanical stimulation on the expression of E-cadherin/cateninin complex in salivary adenoid cystic carcinoma]. Hua Xi Kou Qiang Yi Xue Za Zhi; 2007 Feb;25(1):29-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Effect of mechanical stimulation on the expression of E-cadherin/cateninin complex in salivary adenoid cystic carcinoma].
  • OBJECTIVE: To investigate the effects of cyclic biaxial mechanical stimulation on adhesion of salivary adenoid cystic carcinoma(SACC) extracellular matrix (ECM) and expression of E-cadherin/cateninin complex in the SACC high metastasis cell lines ACC-M, SACC low metastasis cells line ACC-2, we observed the functions of mechanical stimulation in the adhesion of SACC cell-ECM and investigate the mechanism in the adhesion of ACC.
  • We think it played an important role in metastasis of the cancer.
  • [MeSH-major] Cadherins. Carcinoma, Adenoid Cystic

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  • (PMID = 17375572.001).
  • [ISSN] 1000-1182
  • [Journal-full-title] Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology
  • [ISO-abbreviation] Hua Xi Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Cadherins
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62. Vidal L, Tsao MS, Pond GR, Cohen EE, Cohen RB, Chen EX, Agulnik M, Hotte S, Winquist E, Laurie S, Hayes DN, Ho J, Dancey J, Siu LL: Fluorescence in situ hybridization gene amplification analysis of EGFR and HER2 in patients with malignant salivary gland tumors treated with lapatinib. Head Neck; 2009 Aug;31(8):1006-12
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  • METHODS: Fluorescence in situ hybridization (FISH) analysis for both EGFR and HER2 gene amplification was performed successfully in the archival tumor specimens of 20 patients with adenoid cystic carcinomas (ACC) and 17 patients with non-ACC, all treated with lapatinib.
  • The finding of HER2:CEP17 ratio as a predictive marker of efficacy to lapatinib warrants further investigation.

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  • [Copyright] Copyright 2009 Wiley Periodicals, Inc.
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  • (PMID = 19309723.001).
  • [ISSN] 1097-0347
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CM / CM062203; United States / NCI NIH HHS / CA / U01 CA132123-01; United States / NCI NIH HHS / CA / CA132123-01; United States / NCI NIH HHS / CM / N01-CM-62203; United States / NCI NIH HHS / CM / N01-CM-57018-16; United States / NCI NIH HHS / CA / U01 CA132123; United States / NCI NIH HHS / CA / N01CM62203; United States / NCI NIH HHS / CM / N01 CM062203
  • [Publication-type] Clinical Trial, Phase II; Comparative Study; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Quinazolines; 0VUA21238F / lapatinib; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; EC 2.7.10.1 / Receptor, ErbB-2
  • [Other-IDs] NLM/ NIHMS95592; NLM/ PMC2711990
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63. Yurut-Caloglu V, Caloglu M, Ozyilmaz F, Saynak M, Cosar-Alas R, Karagol H, Bayir-Angin G, Uzal C: Lung, bone, skeletal muscles and cutaneous metastases from adenoid cystic carcinoma of the parotid gland: a case report and review of the literature. Med Oncol; 2007;24(4):458-62
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  • [Title] Lung, bone, skeletal muscles and cutaneous metastases from adenoid cystic carcinoma of the parotid gland: a case report and review of the literature.
  • Adenoid cystic carcinoma is the second most common malignancy of the major and minor salivary glands after mucoepidemoid carcinoma.
  • Skeletal muscle and cutaneous metastases from adenoid cystic carcinoma of the parotid gland are extremely rare.
  • In this case, a 40-year-old man with lung and bone metastases followed by skeletal muscle and cutaneous metastases from adenoid cystic carcinoma of the right parotid gland is presented.
  • [MeSH-major] Bone Neoplasms / diagnosis. Carcinoma, Adenoid Cystic / diagnosis. Lung Neoplasms / diagnosis. Muscle Neoplasms / diagnosis. Parotid Neoplasms / pathology. Skin Neoplasms / diagnosis

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  • (PMID = 17917100.001).
  • [ISSN] 1357-0560
  • [Journal-full-title] Medical oncology (Northwood, London, England)
  • [ISO-abbreviation] Med. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 26
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6
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4. Doshi DV, Tripathi U, Dave RI, Pandya SJ, Shukla HK, Parikh BC: Rare tumors of sinonasal track. Indian J Otolaryngol Head Neck Surg; 2010 Jun;62(2):111-7
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  • METHODS: Clinical data from the cases of rare sinonasal malignancies at Gujarat Cancer and Research Institute during 2001-2007 were extracted.
  • Data for histologic type of tumor, tumor stage and survival were analyzed.
  • In this study, we found minor salivary gland tumor in 31 patients, sarcoma in 19 patients, spindle cell carcinoma (SpCC) in 19 patients, undifferentiated carcinoma in 9 patients, lymphoma in 6 patients and melanoma in 3 patients.
  • Adenoid cystic carcinoma exhibited the best survival rate (3 years survival rate was 77%), whereas melanoma and undifferentiated carcinoma exhibited poor survivals (1 year survival was 25% and 33%, respectively and 3 years survival rate is 0%).
  • CONCLUSIONS: Adenoid cystic carcinoma is the most common squamous cell carcinoma (SCC) of the sinonasal track.
  • Survival for the patients with undifferentiated carcinoma and melanoma involving the sinonasal track is poor.

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  • (PMID = 23120695.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3450295
  • [Keywords] NOTNLM ; Clinical features / Rare tumor / Sino nasal
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65. Ferrazzo KL, Alves SM Jr, Santos E, Martins MT, de Sousa SM: Galectin-3 immunoprofile in adenoid cystic carcinoma and polymorphous low-grade adenocarcinoma of salivary glands. Oral Oncol; 2007 Jul;43(6):580-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Galectin-3 immunoprofile in adenoid cystic carcinoma and polymorphous low-grade adenocarcinoma of salivary glands.
  • Adenoid cystic carcinoma (ACC) and polymorphous low-grade adenocarcinoma (PLGA) are malignant neoplasms of salivary glands, which are similar in histologic patterns but very different in clinical behavior, treatment and prognosis.
  • Galectin-3 is a multifunctional protein of a growing family of beta-galactoside-binding animal lectins, which is implicated in a variety of biological events such as tumor cell adhesion, proliferation, differentiation and angiogenesis.
  • This protein was found to be implicated in cellular transformation and a correlation between its expression and cancer progression and metastasis has been described.
  • [MeSH-major] Carcinoma, Adenoid Cystic / metabolism. Carcinoma, Adenoid Cystic / pathology. Galectin 3 / metabolism. Salivary Gland Neoplasms / metabolism. Salivary Gland Neoplasms / pathology


66. Florentine BD, Fink T, Avidan S, Braslavsky D, Raza A, Cobb CJ: Extra-salivary gland presentations of adenoid cystic carcinoma: a report of three cases. Diagn Cytopathol; 2006 Jul;34(7):491-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extra-salivary gland presentations of adenoid cystic carcinoma: a report of three cases.
  • Adenoid cystic carcinoma (ACC) is a malignant neoplasm most commonly originating in salivary glands of the head and neck area.
  • When ACC presents outside of these locations, the diagnosis may become more challenging.
  • Case 3 was a primary bronchial ACC.
  • In conclusion, ACC can present in various body sites and cytologists must consider this neoplasm when presented with a basaloid carcinoma of uncertain origin.
  • [MeSH-major] Bone Neoplasms / secondary. Carcinoma, Adenoid Cystic / secondary. Lung Neoplasms / secondary. Pleural Effusion / pathology

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  • [Copyright] Copyright 2006 Wiley-Liss, Inc.
  • (PMID = 16783770.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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67. Joshi NP, Haresh KP, Das P, Kumar R, Prabhakar R, Sharma DN, Heera P, Julka PK, Rath GK: Unresectable basaloid squamous cell carcinoma of the trachea treated with concurrent chemoradiotherapy: a case report with review of literature. J Cancer Res Ther; 2010 Jul-Sep;6(3):321-3
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  • [Title] Unresectable basaloid squamous cell carcinoma of the trachea treated with concurrent chemoradiotherapy: a case report with review of literature.
  • Basaloid squamous cell carcinoma is an uncommon variant of squamous cell carcinoma of the trachea.
  • We describe the case of an unresectable basaloid squamous cell carcinoma of the trachea treated with concurrent chemoradiotherapy up to a dose of 60 Gy in 33 fractions with weekly paclitaxel and carboplatin.
  • The pathological recognition of basaloid squamous cell carcinoma and its distinction from adenoid cystic carcinoma of the trachea is important for its management.
  • Combining systemic chemotherapy with locoregional radiation is a logical approach to treatment, especially for the basaloid squamous cell carcinoma of the trachea, given its tendency to metastasize early after definitive therapy.
  • [MeSH-major] Carcinoma, Squamous Cell / therapy. Tracheal Neoplasms / therapy

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  • (PMID = 21119264.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
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68. Kim MS, Park K, Kim JH, Kim YD, Lee JI: Gamma knife radiosurgery for orbital tumors. Clin Neurol Neurosurg; 2008 Dec;110(10):1003-7
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  • PATIENTS AND METHODS: Fifteen patients with orbital tumors (7 meningiomas, 3 cavernous hemangiomas, 2 schwannomas, 2 metastatic tumors and 1 adenoid cystic carcinoma of the lacrimal gland) were treated.

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  • (PMID = 18653273.001).
  • [ISSN] 0303-8467
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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69. Katori H, Nozawa A, Tsukuda M: Increased expression of cyclooxygenase-2 and Ki-67 are associated with malignant transformation of pleomorphic adenoma. Auris Nasus Larynx; 2007 Mar;34(1):79-84
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Increased expression of cyclooxygenase-2 and Ki-67 are associated with malignant transformation of pleomorphic adenoma.
  • OBJECTIVES: In the present study, we attempted to identify cyclooxygenase-2 (COX-2) expression and Ki-67 index in carcinoma ex-pleomorphic adenoma (Ca ex-PA) using quantitative immunohistochemical analysis and to compare the benign component of the neoplasia.
  • All Ca ex-PA showed only one malignant histological component: adenocarcinoma (23 cases), adenoid-cystic carcinoma (10), epithelial-myoepithelial carcinoma (7).
  • RESULTS: In the immunohistochemical analysis of COX-2 and Ki-67 index, significant increase was observed in Ca ex-PA, especially with adenocarcinoma, compared to pleomorphic adenoma and sialadenitis.
  • CONCLUSIONS: The data support the hypothesis that increased COX-2 expression is associated with early events in malignant transformation of pleomorphic adenoma.
  • [MeSH-major] Adenoma, Pleomorphic / immunology. Cell Transformation, Neoplastic / metabolism. Cyclooxygenase 2 / immunology. Ki-67 Antigen / immunology. Parotid Neoplasms / immunology. Salivary Gland Neoplasms / immunology

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  • (PMID = 17049779.001).
  • [ISSN] 0385-8146
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antibodies; 0 / Ki-67 Antigen; EC 1.14.99.1 / Cyclooxygenase 2
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70. Nakao N, Itakura T: Sublabial transnasal approach combined with a partial resection of the nasal floor for midline skull base tumors. J Clin Neurosci; 2007 Mar;14(3):267-72
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We performed this approach in three patients with midline cranial base lesions, including invasive pituitary adenoma involving the whole clivus, fibrous dysplasia, and adenocystic carcinoma.
  • [MeSH-major] Adenoma / surgery. Neurosurgical Procedures / methods. Pituitary Neoplasms / surgery. Skull Base Neoplasms / surgery
  • [MeSH-minor] Adult. Carcinoma, Adenoid Cystic / pathology. Carcinoma, Adenoid Cystic / surgery. Female. Fibrous Dysplasia of Bone / pathology. Fibrous Dysplasia of Bone / surgery. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Nasal Cavity / surgery. Sphenoid Bone / surgery

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  • (PMID = 17258136.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Technical Report
  • [Publication-country] Scotland
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71. Maiorano E, Favia G, Pece S, Resta L, Maisonneuve P, Di Fiore PP, Capodiferro S, Urbani U, Viale G: Prognostic implications of NUMB immunoreactivity in salivary gland carcinomas. Int J Immunopathol Pharmacol; 2007 Oct-Dec;20(4):779-89
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Prognostic implications of NUMB immunoreactivity in salivary gland carcinomas.
  • We set out to explore the immunohistochemical expression of Numb in normal and neoplastic (28 adenoid cystic and 34 mucoepidermoid carcinomas) salivary glands, and correlated the results with the clinico-pathologic features of the neoplasms.
  • In salivary carcinomas, we detected diffuse and intense Numb immunostaining in 5 adenoid cystic and 8 mucoepidermoid carcinomas.
  • By contrast, the majority of adenoid cystic and mucoepidermoid cancers showed only moderate (14 and 5 cases) or focal staining (9 and 21 cases), respectively.
  • The corresponding expression of Numb mRNA was documented in normal parotid gland and adenoid cystic carcinoma.
  • Numb immunoreactivity was inversely correlated with the histological grade and Ki-67 immunoreactivity of both adenoid cystic and mucoepidermoid carcinomas.
  • In addition, while tumor grade, stage, Ki-67 and Numb immunoreactivity were associated with disease-free survival in univariate analysis, only Numb and Ki-67 immunoreactivities retained independent prognostic significance in multivariate analysis.
  • These data suggest that loss of Numb is implicated in aberrant differentiation programs of salivary gland carcinomas and may serve as a prognostic indicator in patients treated for these neoplasms.
  • [MeSH-major] Carcinoma, Adenoid Cystic / genetics. Carcinoma, Mucoepidermoid / genetics. Membrane Proteins / genetics. Nerve Tissue Proteins / genetics. Salivary Gland Neoplasms / genetics

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  • (PMID = 18179751.001).
  • [ISSN] 0394-6320
  • [Journal-full-title] International journal of immunopathology and pharmacology
  • [ISO-abbreviation] Int J Immunopathol Pharmacol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Neoplasm; 0 / Ki-67 Antigen; 0 / Membrane Proteins; 0 / Nerve Tissue Proteins; 0 / Numb protein, human; 0 / RNA, Neoplasm
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72. Chen AM, Garcia J, Bucci MK, Quivey JM, Eisele DW: The role of postoperative radiation therapy in carcinoma ex pleomorphic adenoma of the parotid gland. Int J Radiat Oncol Biol Phys; 2007 Jan 1;67(1):138-43
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  • [Title] The role of postoperative radiation therapy in carcinoma ex pleomorphic adenoma of the parotid gland.
  • PURPOSE: To evaluate the impact of postoperative radiation therapy on the clinical course of patients with carcinoma ex pleomorphic adenoma of the parotid gland.
  • METHODS AND MATERIALS: Between 1960 and 2004, 63 patients were treated with definitive surgery for carcinoma ex pleomorphic adenoma of the parotid gland.
  • Adenocarcinoma (29 patients), salivary duct carcinoma (16 patients), and adenoid cystic carcinoma (9 patients) were the most common malignant subtypes.
  • Overall survival was 16% for patients with pathologic N-positive disease compared with 67% for those whose lymph node status was negative or unknown (p = 0.001).
  • CONCLUSION: Surgery followed by postoperative radiation should be considered the standard of care for patients with carcinoma ex pleomorphic adenoma.
  • [MeSH-major] Adenoma, Pleomorphic / radiotherapy. Parotid Neoplasms / radiotherapy
  • [MeSH-minor] Adenocarcinoma / mortality. Adenocarcinoma / radiotherapy. Adenocarcinoma / surgery. Adult. Aged. Carcinoma, Adenoid Cystic / mortality. Carcinoma, Adenoid Cystic / radiotherapy. Carcinoma, Adenoid Cystic / surgery. Combined Modality Therapy / methods. Female. Humans. Male. Middle Aged. Neoplasm Staging. Postoperative Period. Radiotherapy Dosage. Salivary Ducts. Salivary Gland Neoplasms / mortality. Salivary Gland Neoplasms / radiotherapy. Salivary Gland Neoplasms / surgery

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  • (PMID = 17049183.001).
  • [ISSN] 0360-3016
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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73. Chikamatsu K, Shino M, Sakakura K, Nakajima K, Sakurai T, Miyashita M, Furuya N: Expression of thymidylate synthase and dihydropyrimidine dehydrogenase in adenoid cystic carcinoma of the head and neck: correlation with clinical outcome. Oral Oncol; 2007 Aug;43(7):662-9
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  • [Title] Expression of thymidylate synthase and dihydropyrimidine dehydrogenase in adenoid cystic carcinoma of the head and neck: correlation with clinical outcome.
  • The purpose of this study was to estimate the possibility of using thymidylate synthase (TS), dihydropyrimidine dehydrogenase (DPD), and p53 as predictive values of clinical outcome in adenoid cystic carcinoma (ACC).
  • [MeSH-major] Carcinoma, Adenoid Cystic / enzymology. Dihydrouracil Dehydrogenase (NADP) / metabolism. Head and Neck Neoplasms / enzymology. Thymidylate Synthase / metabolism

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  • (PMID = 17070099.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Tumor Suppressor Protein p53; EC 1.3.1.2 / Dihydrouracil Dehydrogenase (NADP); EC 2.1.1.45 / Thymidylate Synthase
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74. Freitas VM, Vilas-Boas VF, Pimenta DC, Loureiro V, Juliano MA, Carvalho MR, Pinheiro JJ, Camargo AC, Moriscot AS, Hoffman MP, Jaeger RG: SIKVAV, a laminin alpha1-derived peptide, interacts with integrins and increases protease activity of a human salivary gland adenoid cystic carcinoma cell line through the ERK 1/2 signaling pathway. Am J Pathol; 2007 Jul;171(1):124-38
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  • [Title] SIKVAV, a laminin alpha1-derived peptide, interacts with integrins and increases protease activity of a human salivary gland adenoid cystic carcinoma cell line through the ERK 1/2 signaling pathway.
  • Adenoid cystic carcinoma is a frequently occurring malignant salivary gland neoplasm.
  • Laminin alpha1 and matrix metalloproteinases (MMPs) 2 and 9 were immunolocalized in adenoid cystic carcinoma cells in vivo and in vitro.
  • We propose that SIKVAV increases protease activity of a human salivary gland adenoid cystic carcinoma cell line through alpha3beta1 and alpha6beta1 integrins and the ERK 1/2 signaling pathway.
  • [MeSH-major] Carcinoma, Adenoid Cystic / metabolism. Integrins / metabolism. Laminin / metabolism. Matrix Metalloproteinases / metabolism. Mitogen-Activated Protein Kinase 1 / metabolism. Mitogen-Activated Protein Kinase 3 / metabolism. Oligopeptides / pharmacology. Salivary Gland Neoplasms / metabolism

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  • (PMID = 17591960.001).
  • [ISSN] 0002-9440
  • [Journal-full-title] The American journal of pathology
  • [ISO-abbreviation] Am. J. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD29; 0 / Integrin alpha6; 0 / Integrins; 0 / Laminin; 0 / Oligopeptides; 146163-06-6 / seryl-isoleucyl-lysyl-valyl-alanyl-valinamide; 151186-83-3 / laminin A; EC 2.7.11.24 / Mitogen-Activated Protein Kinase 1; EC 2.7.11.24 / Mitogen-Activated Protein Kinase 3; EC 3.4.24.- / Matrix Metalloproteinases; EC 3.4.24.24 / Matrix Metalloproteinase 2; EC 3.4.24.35 / Matrix Metalloproteinase 9
  • [Other-IDs] NLM/ PMC1941583
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75. Albores-Saavedra J, Heard SC, McLaren B, Kamino H, Witkiewicz AK: Cylindroma (dermal analog tumor) of the breast: a comparison with cylindroma of the skin and adenoid cystic carcinoma of the breast. Am J Clin Pathol; 2005 Jun;123(6):866-73
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  • [Title] Cylindroma (dermal analog tumor) of the breast: a comparison with cylindroma of the skin and adenoid cystic carcinoma of the breast.
  • We compared 4 breast cylindromas with 50 dermal cylindromas and 8 adenoid cystic breast carcinomas.
  • Except for a modest increase in the number of eccrine ducts and reactive Langerhans cells in dermal cylindromas, breast and dermal cylindromas showed identical histologic and immunohistochemical features.
  • Clusters of sebaceous cells and a few eccrine ducts are described in breast cylindromas.
  • Cytokeratin 7 labeled predominantly the central basaloid cells, and smooth muscle actin stained peripheral myoepithelial cells in breast and dermal cylindromas.
  • Cylindromas of the breast and skin did not express cytokeratin 20, gross cystic disease fluid protein 15, or estrogen or progesterone receptor.
  • Breast cylindroma might be confused with the solid variant of adenoid cystic carcinoma, especially in needle core biopsy specimens, because they share nodular and trabecular patterns, basaloid cells, myoepithelial cells, eccrine ducts, and hyaline globules of basement membrane material.
  • However, adenoid cystic carcinoma displays an infiltrative growth pattern, cytologic atypia, and mitotic figures and lacks the continuous, thickened basement membrane.
  • [MeSH-major] Breast Neoplasms / pathology. Carcinoma, Adenoid Cystic / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Middle Aged. Sweat Glands / pathology

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  • (PMID = 15899777.001).
  • [ISSN] 0002-9173
  • [Journal-full-title] American journal of clinical pathology
  • [ISO-abbreviation] Am. J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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76. Hodgson NC, Lytwyn A, Bacopulos S, Elavathil L: Adenoid cystic breast carcinoma: high rates of margin positivity after breast conserving surgery. Am J Clin Oncol; 2010 Feb;33(1):28-31
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  • [Title] Adenoid cystic breast carcinoma: high rates of margin positivity after breast conserving surgery.
  • INTRODUCTION: Adenoid cystic carcinoma of the breast (ACCB) is a rare malignancy with favorable prognosis: axillary lymph node involvement, distant metastases, and death due to disease are uncommon.
  • METHODS: Pathology database searched to identify patients diagnosed with ACCB between 1988 and 2007 at Hamilton Health Sciences Centre, Hamilton, Ontario, Canada.Two pathologists independently reviewed histology to confirm diagnosis of ACCB, and documented surgical procedure, tumor size, tumor grade, surgical margin, and lymph node status.
  • [MeSH-major] Breast Neoplasms / pathology. Carcinoma, Adenoid Cystic / pathology. Mastectomy. Mastectomy, Segmental. Neoplasm Recurrence, Local / pathology


77. Ko YH, Lee MA, Hong YS, Lee KS, Jung CK, Kim YS, Sun DI, Kim BS, Kim MS, Kang JH: Prognostic factors affecting the clinical outcome of adenoid cystic carcinoma of the head and neck. Jpn J Clin Oncol; 2007 Nov;37(11):805-11
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  • [Title] Prognostic factors affecting the clinical outcome of adenoid cystic carcinoma of the head and neck.
  • BACKGROUND: Adenoid cystic carcinoma (ACC) is an uncommon tumor, constituting approximately 10% of all head and neck tumors.
  • The overall 3- and 5-year survival was 87.4% and 55.3%, respectively, whereas the 3- and 5-year disease-free survival was 64.3% and 36.1%, respectively.
  • [MeSH-major] Carcinoma, Adenoid Cystic / mortality. Head and Neck Neoplasms / mortality

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  • (PMID = 18057012.001).
  • [ISSN] 1465-3621
  • [Journal-full-title] Japanese journal of clinical oncology
  • [ISO-abbreviation] Jpn. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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78. Carlsten JR, Lewis MD, Saddler K, Reilly P, Pan T, Gnepp DR, Robinson-Bostom L: Spiradenocylindrocarcinoma: a malignant hybrid tumor. J Cutan Pathol; 2005 Feb;32(2):166-71
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  • BACKGROUND: Eccrine spiradenomas and cylindromas are benign, slowly growing, cutaneous adnexal neoplasms, recently hypothesized to arise from a common pluripotential cell; malignant variants are rare.
  • We found 48 cases of malignant spiradenomas and 33 cases of malignant cylindromas reported in the English literature.
  • Recent immunohistochemical studies of these two tumors have provided compelling evidence that these two tumors may merely represent a single tumor type with a spectrum of histological features.
  • CASE REPORT: We describe two cases of a malignant variant of this rare hybrid tumor occurring in a 62-year-old male and a 72-year-old female.
  • CONCLUSION: We propose the term 'spiradenocylindrocarcinoma' to describe malignant tumors with features of both a spiradenoma and a cylindroma.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Carcinoma, Adenoid Cystic / pathology. Neoplasms, Multiple Primary / pathology. Skin Neoplasms / pathology. Sweat Gland Neoplasms / pathology

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  • [ErratumIn] J Cutan Pathol. 2005 Jul;32(6):453
  • (PMID = 15606677.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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79. Makimoto Y, Yamamoto S, Takano H, Motoori K, Ueda T, Kazama T, Kaneoya K, Shimofusa R, Uno T, Ito H, Hanazawa T, Okamoto Y, Hayasaki K: Imaging findings of radiation-induced sarcoma of the head and neck. Br J Radiol; 2007 Oct;80(958):790-7
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  • We reviewed the records of 4194 patients with carcinoma of the head and neck region who had a history of radiation.
  • Medical records were reviewed for the primary diagnosis, radiation history and latency period to the development of sarcoma.
  • Primary diagnoses were maxillary carcinoma, nasopharyngeal carcinoma, adenoid cystic carcinoma of the oral floor, tonsilar carcinoma, soft palate carcinoma and tongue carcinoma.
  • Histopathological examinations revealed osteosarcoma, spindle cell sarcoma, chondrosarcoma, malignant peripheral nerve sheath tumour, spindle cell carcinoma and malignant fibrous histiocytoma, respectively.
  • This emphasizes the importance of the earliest possible diagnosis for such patients.
  • The imaging findings are not diagnosis specific, but strict follow-up within the radiation field by CT and MRI and an appreciation of the expected latency period may help to provide the diagnosis.
  • [MeSH-major] Head and Neck Neoplasms / diagnosis. Neoplasms, Radiation-Induced / diagnosis. Sarcoma / diagnosis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Carcinoma / radiotherapy. Fatal Outcome. Female. Humans. Incidence. Japan. Magnetic Resonance Imaging. Male. Middle Aged. Prognosis. Retrospective Studies. Tomography, X-Ray Computed


80. Epivatianos A, Poulopoulos A, Dimitrakopoulos I, Andreadis D, Nomikos A, Vlahou S, Papazoglou G, Barbatis C: Application of alpha-smooth muscle actin and c-kit in the differential diagnosis of adenoid cystic carcinoma from polymorphous low-grade adenocarcinoma. Oral Oncol; 2007 Jan;43(1):67-76
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  • [Title] Application of alpha-smooth muscle actin and c-kit in the differential diagnosis of adenoid cystic carcinoma from polymorphous low-grade adenocarcinoma.
  • The expression of vimentin, alpha-smooth muscle actin (alpha-SMA) and c-kit in adenoid cystic carcinomas (AdCCs) and polymorphous low-grade adenocarcinomas (PLGAs) was investigated immunohistochemically to evaluate the application of these markers to distinguish AdCCs from PLGAs when the histological features are equivocal.
  • The immunoreactivity of c-kit in all positive cases of AdCCs (83%) and PLGAs (41%) was more than 50% and less than 50% of tumor cells respectively.
  • The results of this study support the potential application of alpha-SMA and c-kit as an adjunctive aid in the differential diagnosis of AdCCs from PLGAs.
  • [MeSH-major] Actins / analysis. Adenocarcinoma / diagnosis. Biomarkers, Tumor / analysis. Carcinoma, Adenoid Cystic / diagnosis. Proto-Oncogene Proteins c-kit / analysis. Vimentin / analysis
  • [MeSH-minor] Cytoskeletal Proteins. Diagnosis, Differential. Humans. Immunohistochemistry. Muscle Proteins. Retrospective Studies

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  • (PMID = 16807072.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Actins; 0 / Biomarkers, Tumor; 0 / Cytoskeletal Proteins; 0 / Muscle Proteins; 0 / Smooth muscle protein, human; 0 / Vimentin; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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81. Luna Ortiz K, Carmona Luna T, Herrera Gómez A, Cano Valdez AM: Macroglossia caused by adenoid cystic carcinoma. Case report. Med Oral Patol Oral Cir Bucal; 2008 Jun;13(6):E395-7
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  • [Title] Macroglossia caused by adenoid cystic carcinoma. Case report.
  • She had been treated before with tracheostomy and gastrostomy due to an adenoid cystic carcinoma (ACC) of the mobile tongue, in clinical stage IVC.
  • The histological report described a 15x11 cm solid type ACC of the mobile tongue (grade III), with infiltration to adjacent soft tissues, vascular and lymphatic vessels, as well as two metastatic lymph nodes in the right neck dissection.
  • [MeSH-major] Carcinoma, Adenoid Cystic / complications. Macroglossia / etiology. Tongue Neoplasms / complications

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  • (PMID = 18521061.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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82. Huang SY, Zhang DS, Zhang SZ, Liu GJ, Mu WL, Zhang J: [Construction of recombinant plasmid vector pIRES-CD and its expression in ACC-2 cells]. Shanghai Kou Qiang Yi Xue; 2008 Oct;17(5):505-9
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  • CONCLUSIONS: The CD gene is successfully amplified and the eukaryotic expression plasmid containing E.coli CD is successfully constructed.The positive ACC-2 cell clones expressing CD gene stably are obtained, which provide a basis for further study of adenoid cystic carcinoma gene therapy with CD/5-FC suicide gene system.

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  • (PMID = 18989593.001).
  • [ISSN] 1006-7248
  • [Journal-full-title] Shanghai kou qiang yi xue = Shanghai journal of stomatology
  • [ISO-abbreviation] Shanghai Kou Qiang Yi Xue
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, CD
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83. Doi Y, Kawamata H, Ono Y, Fujimori T, Imai Y: Expression and cellular localization of TSC-22 in normal salivary glands and salivary gland tumors: implications for tumor cell differentiation. Oncol Rep; 2008 Mar;19(3):609-16
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  • TGF-beta-stimulated clone-22 (TSC-22) was reported to be a differentiation-inducing factor which negatively regulates the growth of salivary gland cancer cells.
  • In pleomorphic adenoma (PA), most of the sparse myoepithelial-like tumor cells, which are considered as the differentiated cells because they produce extracellular matrix, expressed TSC-22.
  • In adenoid cystic carcinoma (ACC), inner ductal cells in the tubular structure, strongly expressed TSC-22, though the outer myoepithelial-like tumor cells did not express TSC-22.
  • Sparse type myoepithelial-like tumor cells in ACC also expressed TSC-22.
  • In mucoepidermoid carcinoma, epidermoid tumor cells and mucous-producing tumor cells in mucoepidermoid carcinoma frequently expressed TSC-22.

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  • (PMID = 18288391.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Repressor Proteins; 0 / TSC22D1 protein, human
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84. Mseddi M, Bouassida S, Marrekchi S, Turki H, Zahaf A: [Tricho-epithelioma multiplex: two cases reports]. Rev Med Brux; 2006 Nov-Dec;27(6):514-7
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  • [Transliterated title] Les tricho-epithéliomes multiples: a propos de deux observations.
  • Histological study confirmed the diagnosis of multiple tricho-epitheliomas.
  • Multiple tricho-epitheliomas is a genodermatosis it is often associated to other benign cutaneous tumors, mainly cylindromas and spiradenomas.
  • Histological examination confirm the diagnosis.
  • [MeSH-major] Carcinoma / pathology. Carcinoma / surgery. Skin Neoplasms / pathology. Skin Neoplasms / surgery

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  • (PMID = 17256419.001).
  • [ISSN] 0035-3639
  • [Journal-full-title] Revue médicale de Bruxelles
  • [ISO-abbreviation] Rev Med Brux
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Belgium
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85. Chakrabarti S, Bera M, Bhattacharya PK, Chakrabarty D, Manna AK, Pathak S, Maiti K: Study of salivary gland lesions with fine needle aspiration cytology and histopothology along with immunohistochemistry. J Indian Med Assoc; 2010 Dec;108(12):833-6
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  • Imaging technique is not so helpful in pre-operative diagnosis; microscopical examination is required for diagnosis.
  • Among these 3 cases, 2 were adenoid cystic carcinoma which was cytologically diagnosed as benign neoplasm (monomorphic adenoma).
  • One case of Warthin's tumour was cytologically diagnosed as pleomorphic adenoma.
  • FNAC is an important tool for early diagnosis of salivary gland lesions.

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  • (PMID = 21661459.001).
  • [ISSN] 0019-5847
  • [Journal-full-title] Journal of the Indian Medical Association
  • [ISO-abbreviation] J Indian Med Assoc
  • [Language] eng
  • [Publication-type] Controlled Clinical Trial; Journal Article
  • [Publication-country] India
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86. Yoshimura T, Sumida T, Liu S, Onishi A, Shintani S, Desprez PY, Hamakawa H: Growth inhibition of human salivary gland tumor cells by introduction of progesterone (Pg) receptor and Pg treatment. Endocr Relat Cancer; 2007 Dec;14(4):1107-16
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  • Cancer of the salivary gland is one of the common cancers in the head and the neck regions.
  • This type of cancer develops in the minor and the major salivary glands, and it sometimes metastasizes to other organs, particularly the lung.
  • Morphologic mimicry and similarity in the expression of steroid hormone receptors between salivary gland tumors (SGTs) and breast tumors are well-known phenomena and are occasionally debated in the field of surgical pathology.
  • Further, it is believed that Pg plays a role in breast cancer progression.
  • In this study, we used ACCM, a human adenoid cystic carcinoma cell line established from the salivary gland, in order to clarify the role of the Pg receptor (PR) on cell proliferation.

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  • (PMID = 18045962.001).
  • [ISSN] 1351-0088
  • [Journal-full-title] Endocrine-related cancer
  • [ISO-abbreviation] Endocr. Relat. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Receptors, Progesterone; 4G7DS2Q64Y / Progesterone; EC 2.7.7.49 / Telomerase
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87. Chen AM, Garcia J, Granchi PJ, Johnson J, Eisele DW: Late recurrence from salivary gland cancer: when does "cure" mean cure? Cancer; 2008 Jan 15;112(2):340-4
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  • [Title] Late recurrence from salivary gland cancer: when does "cure" mean cure?
  • BACKGROUND: The purpose of the current study was to determine the incidence of late recurrences, which were defined as those occurring >or=5 years after initial therapy, among patients treated for salivary gland cancer.
  • METHODS: Between 1960 and 2000, 145 patients underwent definitive therapy for localized carcinomas of the salivary glands and were clinically without evidence of disease at 5 years of follow-up.
  • RESULTS: The 10-year and 15-year cumulative probabilities of late recurrence in patients who were free of disease at 5 years were 13% and 18%, respectively.
  • The crude rates of late recurrence by histologic subtype were adenoid cystic carcinoma (26%), mixed malignant tumor (25%), mucoepidermoid carcinoma (17%), adenocarcinoma (10%), and acinic cell carcinoma (8%).
  • Salvage treatment varied according to location of disease recurrence and initial treatment characteristics.
  • The 15-year estimate of overall survival was 39% for patients who experienced a late recurrence compared with 71% for those who remained free of disease (P= .001).
  • CONCLUSIONS: A significant proportion of patients who are presumed to be cured of their disease at 5 years after initial treatment for salivary gland cancer will be found to develop late disease recurrence with additional follow-up.


88. Nakashima D, Uzawa K, Kasamatsu A, Koike H, Endo Y, Saito K, Hashitani S, Numata T, Urade M, Tanzawa H: Protein expression profiling identifies maspin and stathmin as potential biomarkers of adenoid cystic carcinoma of the salivary glands. Int J Cancer; 2006 Feb 1;118(3):704-13
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  • [Title] Protein expression profiling identifies maspin and stathmin as potential biomarkers of adenoid cystic carcinoma of the salivary glands.
  • Adenoid cystic carcinoma (ACC) is one of the most common malignant tumors of the salivary glands.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Carcinoma, Adenoid Cystic / metabolism. Proteomics. Salivary Gland Neoplasms / metabolism. Salivary Glands / metabolism. Serpins / metabolism. Stathmin / metabolism

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  • [Copyright] Copyright 2005 Wiley-Liss, Inc.
  • (PMID = 16094606.001).
  • [ISSN] 0020-7136
  • [Journal-full-title] International journal of cancer
  • [ISO-abbreviation] Int. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / SERPIN-B5; 0 / Serpins; 0 / Stathmin
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89. Daneshbod Y, Daneshbod K, Khademi B: Diagnostic difficulties in the interpretation of fine needle aspirate samples in salivary lesions: diagnostic pitfalls revisited. Acta Cytol; 2009 Jan-Feb;53(1):53-70
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  • STUDY DESIGN: In a retrospective review of cytology files of a head and neck referral center from 1990 to 2005, the false positive and false negative interpretations on fine needle aspiration (FNA) of salivary lesions were retrieved.
  • These records and slides were reviewed to identify cytologic characteristics that contributed to false diagnosis.
  • RESULTS: Of a total of 1,040 salivary FNA samples, 376 cases had a final histologic diagnosis with interpretations of benign or malignant.
  • The most common false negative cases were acinic cell carcinoma, epithelial myoepithelial carcinoma, adenoid cystic carcinoma and basal cell adenocarcinoma.
  • Benign cases with false positive diagnosis were Warthin tumor and pleomorphic adenoma.
  • CONCLUSION: Knowledge of cytologic overlaps and pitfalls on salivary gland FNA, as well as clinical and radiologic features, may help clinicians arrive at the appropriate diagnosis and reduce false interpretations.
  • Several clinically important pitfalls with nonsalivary tumors of jaw and skin are demonstrated in our series.
  • [MeSH-major] Salivary Gland Neoplasms / diagnosis. Salivary Glands / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biopsy, Fine-Needle. Child. Child, Preschool. Diagnosis, Differential. False Negative Reactions. False Positive Reactions. Female. Humans. Infant. Male. Middle Aged. Retrospective Studies. Sensitivity and Specificity. Young Adult

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  • (PMID = 19248555.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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90. Unsal A, Karaman CZ, Kacar F, Sen S: [Atypically located pulmonary adenoid cystic carcinoma: case report]. Tuberk Toraks; 2008;56(2):210-4
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  • [Title] [Atypically located pulmonary adenoid cystic carcinoma: case report].
  • [Transliterated title] Atipik yerleşimli pulmoner adenoid kistik karsinom: Olgu sunumu.
  • Pulmonary adenoid cystic carcinomas typically arise from central extra-pulmonary airways and lung involvement is rare.
  • On the other hand, this entity should be kept in mind because it has a more favorable clinical course compared to the primary lung adenocarcinoma.
  • In this paper; the clinical, radiological and pathological aspects of a 47 years old man with a complaint of chronic cough, who was found to have a mass lesion at upper lobe of right lung and a final diagnosis of primary pulmonary adenoid cystic carcinoma according to transbronchial needle biopsy and pneumonectomy, was presented.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Lung Neoplasms / pathology. Pneumonectomy / methods
  • [MeSH-minor] Biopsy, Fine-Needle / methods. Bronchoscopy / methods. Diagnosis, Differential. Humans. Male. Middle Aged

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  • (PMID = 18701983.001).
  • [ISSN] 0494-1373
  • [Journal-full-title] Tüberküloz ve toraks
  • [ISO-abbreviation] Tuberk Toraks
  • [Language] tur
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Turkey
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91. Jiménez-Heffernan JA, Pérez F, Tobio R, Vicandi B: Adenoid cystic carcinoma of the parotid metastatic to the kidney: diagnosis by fine needle aspiration cytology. Acta Cytol; 2007 Jan-Feb;51(1):117-8
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  • [Title] Adenoid cystic carcinoma of the parotid metastatic to the kidney: diagnosis by fine needle aspiration cytology.
  • [MeSH-major] Carcinoma, Adenoid Cystic / secondary. Kidney Neoplasms / secondary. Parotid Neoplasms / pathology

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  • (PMID = 17328512.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
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92. Mithani SK, Shao C, Tan M, Smith IM, Califano JA, El-Naggar AK, Ha PK: Mitochondrial mutations in adenoid cystic carcinoma of the salivary glands. PLoS One; 2009 Dec 30;4(12):e8493
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  • [Title] Mitochondrial mutations in adenoid cystic carcinoma of the salivary glands.
  • No studies have investigated mitochondrial mutation in salivary gland adenoid cystic carcinomas.
  • METHODOLOGY: The entire mitochondrial genome of 22 salivary gland adenoid cystic carcinomas (ACC) of salivary glands and matched leukocyte DNA was sequenced to determine the frequency and distribution of mitochondrial mutations in ACC tumors.

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  • (PMID = 20041111.001).
  • [ISSN] 1932-6203
  • [Journal-full-title] PloS one
  • [ISO-abbreviation] PLoS ONE
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P20 CA118782; United States / NIDCR NIH HHS / DE / K08DE018463; United States / NIDCR NIH HHS / DE / R01 DE015939; United States / NIDCR NIH HHS / DE / 9P50DE019032; United States / NIDCR NIH HHS / DE / 1R01DE015939; United States / NCI NIH HHS / CA / 5P20CA118782; United States / NIDCR NIH HHS / DE / P50 DE019032; United States / NIDCR NIH HHS / DE / K08 DE018463
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Amino Acids; 0 / DNA, Mitochondrial; 0U46U6E8UK / NAD
  • [Other-IDs] NLM/ PMC2795173
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93. Zhengjaiang L, Pingzhang T, Dechao Z, Reddy-Kolanu G, Ilankovan V: Primary tracheal tumours: 21 years of experience at Peking Union Medical College, Beijing, China. J Laryngol Otol; 2008 Nov;122(11):1235-40
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  • Sixty-nine patients had malignant tumours, most commonly adenoid cystic carcinoma (50.7 per cent) or squamous cell carcinoma (30.4 per cent).
  • The five-year survival rates for adenoid cystic carcinoma and squamous cell carcinoma were 40.2 and 24.6 per cent, respectively.
  • [MeSH-major] Carcinoma, Adenoid Cystic / therapy. Carcinoma, Squamous Cell / therapy. Tracheal Neoplasms / therapy

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  • (PMID = 18331654.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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94. Pedro Silva IE, Osorio Acosta V, Farfán Chávez FA: [Cystic adenoid carcinoma of the prostate. Report of two cases]. Arch Esp Urol; 2006 Oct;59(8):823-5
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  • [Title] [Cystic adenoid carcinoma of the prostate. Report of two cases].
  • [Transliterated title] Carcinoma adenoideo quístico de la próstata. Presentación de 2 casos.
  • OBJECTIVE: We report two cases with the pathologic diagnosis of cystic adenoid carcinoma of the prostate, an extremely rare tumor.
  • METHODS: We evaluate two patients with different age, clinical presentation, diagnosis, treatment and outcome.
  • CONCLUSIONS: The clinical presentation is non specific, with the diagnosis generally obtained by transurethral resection or transrectal biopsy after the suspicion of an abnormal digital rectal examination or ultrasound.
  • [MeSH-major] Carcinoma, Adenoid Cystic / diagnosis. Prostatic Neoplasms / diagnosis


95. Semra Turki I, Miaoui A, Chammekhi R, Kchaw I, Ghorbel D, Nouira K, Menif E: [Adenoid cystic carcinoma of parotid gland: case report]. Tunis Med; 2008 Jan;86(1):92-3
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  • [Title] [Adenoid cystic carcinoma of parotid gland: case report].
  • [Transliterated title] Carcinome adénoïde kystique de la parotide.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Parotid Neoplasms / pathology

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  • (PMID = 19472715.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Tunisia
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96. Seethala RR, Pasha TL, Raghunath PN, Livolsi VA, Zhang PJ: The selective expression of CD43 in adenoid cystic carcinoma. Appl Immunohistochem Mol Morphol; 2008 Mar;16(2):165-72
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  • [Title] The selective expression of CD43 in adenoid cystic carcinoma.
  • We describe CD43 expression by immunohistochemistry and mRNA in situ hybridization in adenoid cystic carcinomas (ACCs).
  • CD43 immunoreactivity with 2 different antibodies was detected mainly in ACC but also 1 membranous type basal cell adenocarcinoma and 1 colonic adenocarcinoma.

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  • (PMID = 18227725.001).
  • [ISSN] 1541-2016
  • [Journal-full-title] Applied immunohistochemistry & molecular morphology : AIMM
  • [ISO-abbreviation] Appl. Immunohistochem. Mol. Morphol.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD43; 0 / RNA, Messenger; 0 / UN1 sialoglycoprotein, human
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97. Tse DT, Benedetto P, Morcos JJ, Johnson TE, Weed D, Dubovy S: An atypical presentation of adenoid cystic carcinoma of the lacrimal gland. Am J Ophthalmol; 2006 Jan;141(1):187-9
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  • [Title] An atypical presentation of adenoid cystic carcinoma of the lacrimal gland.
  • PURPOSE: To report a case of lacrimal gland adenoid cystic carcinoma (ACC) with an atypical initial presentation and to postulate an anatomical explanation for this unusual biologic behavior.
  • METHODS: An orbital magnetic resonance imaging study of a 58-year-old man who complained of progressive diplopia and orbital discomfort disclosed a soft tissue mass in the left cavernous sinus and orbital apex.
  • CONCLUSIONS: In patients presenting with an infiltrative mass in the cavernous sinus or orbital apex, metastatic disease from an occult lacrimal gland primary should be considered, even with a normal-appearing lacrimal gland.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Eye Neoplasms / pathology. Lacrimal Apparatus Diseases / pathology. Orbital Neoplasms / pathology. Paranasal Sinus Neoplasms / pathology

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  • (PMID = 16386996.001).
  • [ISSN] 0002-9394
  • [Journal-full-title] American journal of ophthalmology
  • [ISO-abbreviation] Am. J. Ophthalmol.
  • [Language] eng
  • [Grant] United States / NEI NIH HHS / EY / P30 EY 014801
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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98. de Fátima Bernardes V, Cardoso SV, Mesquita RA, do Carmo MA, de Aguiar MC: Adenoid cystic carcinoma in palate and maxillary sinus. Braz J Otorhinolaryngol; 2006 Jul-Aug;72(4):573
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenoid cystic carcinoma in palate and maxillary sinus.
  • [MeSH-major] Carcinoma, Adenoid Cystic / diagnosis. Maxillary Sinus Neoplasms / diagnosis. Palatal Neoplasms / diagnosis

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  • (PMID = 17143441.001).
  • [ISSN] 1808-8694
  • [Journal-full-title] Brazilian journal of otorhinolaryngology
  • [ISO-abbreviation] Braz J Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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99. Li L, Luo W, Gan X, Su L, Zeng W: [Adenoid cystic carcinoma of ENT associated with hard lump: a report of 9 cases]. Lin Chuang Er Bi Yan Hou Ke Za Zhi; 2006 Oct;20(19):875-7
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  • [Title] [Adenoid cystic carcinoma of ENT associated with hard lump: a report of 9 cases].
  • OBJECTIVE: To assess the clinical and pathological features of the patients with ENT adenoid cystic carcinoma (ENTACC) who presented with hard lump, and to detect its prognosis.
  • RESULT: The period from the occurrence of primary symptoms to definite diagnosis was 4 years and 3 months on average.
  • CONCLUSION: The pathological result of these 9 cases were all salivary gland derived adenoid cystic carcinoma of solid type.
  • [MeSH-major] Carcinoma, Adenoid Cystic. Salivary Gland Neoplasms

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  • (PMID = 17168112.001).
  • [Journal-full-title] Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology
  • [ISO-abbreviation] Lin Chuang Er Bi Yan Hou Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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100. Dincer N, Tezel GG, Sungur A, Himmetoglu C, Huebner K, Güler G: Study of FHIT and WWOX expression in mucoepidermoid carcinoma and adenoid cystic carcinoma of salivary gland. Oral Oncol; 2010 Mar;46(3):195-9
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  • [Title] Study of FHIT and WWOX expression in mucoepidermoid carcinoma and adenoid cystic carcinoma of salivary gland.
  • Mucoepidermoid carcinoma (MEC) and adenoid cystic carcinoma (ACC) are salivary gland neoplasms with divergent morphological features and clinical behavior.
  • In previous studies, we have shown concordant loss of Fhit and Wwox expression in breast cancer, with significantly more frequent loss in cancers of basal-like phenotype.
  • Correlations among immunohistochemical markers and histological type were determined by statistical analyses.
  • The results suggest that, as for breast cancer, loss of Fhit and Wwox expression might have a role in the pathogenesis of basaloid differentiation in salivary gland neoplasms; alternatively, differences in chromatin structure at chromosome fragile regions might make fragile genes more accessible to DNA damage and rearrangement early during preneoplastic stages of basaloid cancers.
  • [MeSH-major] Acid Anhydride Hydrolases / metabolism. Carcinoma, Adenoid Cystic / metabolism. Carcinoma, Mucoepidermoid / metabolism. Neoplasm Proteins / metabolism. Oxidoreductases / metabolism. Salivary Gland Neoplasms / metabolism. Tumor Suppressor Proteins / metabolism

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  • [Copyright] (c) 2009 Elsevier Ltd. All rights reserved.
  • (PMID = 20060354.001).
  • [ISSN] 1879-0593
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Neoplasm Proteins; 0 / Tumor Suppressor Proteins; 0 / fragile histidine triad protein; EC 1.- / Oxidoreductases; EC 1.1.1.- / WWOX protein, human; EC 3.6.- / Acid Anhydride Hydrolases
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