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41. Hosaka Y, Tsuchida M, Umezu H, Eimoto T, Hashimoto T, Shinohara H, Hayashi J: Primary thymic adenocarcinoma coexisting with type AB thymoma: a rare case with long-term survival. Gen Thorac Cardiovasc Surg; 2010 Sep;58(9):488-91; discussion 491-2
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  • [Title] Primary thymic adenocarcinoma coexisting with type AB thymoma: a rare case with long-term survival.
  • Thymic carcinoma is a rare tumor.
  • The most common histological subtype is squamous cell carcinoma, and only a few cases of thymic adenocarcinoma have been reported.
  • A case of papillary adenocarcinoma of thymic origin that coexisted with type AB thymoma as a separate nodule is presented herein.
  • On pathological examination, two tumors, which were diagnosed as papillary adenocarcinoma and type AB thymoma, respectively, were present in the thymus without any connection with each other.
  • We diagnosed the adenocarcinoma in this case was a primary thymic carcinoma.
  • [MeSH-major] Adenocarcinoma, Papillary / complications. Thymoma / complications. Thymus Neoplasms / complications

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  • (PMID = 20859731.001).
  • [ISSN] 1863-6713
  • [Journal-full-title] General thoracic and cardiovascular surgery
  • [ISO-abbreviation] Gen Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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42. O'Donoghue K, Sultan HA, Al-Allaf FA, Anderson JR, Wyatt-Ashmead J, Fisk NM: Microchimeric fetal cells cluster at sites of tissue injury in lung decades after pregnancy. Reprod Biomed Online; 2008 Mar;16(3):382-90
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  • Male cells were identified in lung/thymus tissue from all women with known male pregnancies, but not in those without sons.
  • The frequency of male microchimeric cells was seven-fold greater in lung/thymus tissues than marrow and was two-fold greater than normal bone from the same women.
  • [MeSH-major] Adenocarcinoma / pathology. Chimerism. Fetal Stem Cells / pathology. Lung / pathology. Lung Neoplasms / pathology. Wound Healing / physiology
  • [MeSH-minor] Aged. Carcinoma, Squamous Cell / pathology. Choristoma / pathology. Female. Fibroma / pathology. Humans. Male. Middle Aged. Pleural Neoplasms / pathology. Pregnancy. Thymus Neoplasms / pathology

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  • (PMID = 18339261.001).
  • [ISSN] 1472-6483
  • [Journal-full-title] Reproductive biomedicine online
  • [ISO-abbreviation] Reprod. Biomed. Online
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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43. Tokairin Y, Kakinuma S, Arai M, Nishimura M, Okamoto M, Ito E, Akashi M, Miki Y, Kawano T, Iwai T, Shimada Y: Accelerated growth of intestinal tumours after radiation exposure in Mlh1-knockout mice: evaluation of the late effect of radiation on a mouse model of HNPCC. Int J Exp Pathol; 2006 Apr;87(2):89-99
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  • Mlh1-/- mice spontaneously developed GIT and thymic lymphomas by 48 weeks.
  • Mlh1+/- and Mlh1+/+ mice were not susceptible to spontaneous or radiation-induced thymic lymphomas and GIT until 72 weeks after birth.
  • [MeSH-minor] Adaptor Proteins, Signal Transducing. Adenocarcinoma / etiology. Animals. Base Pair Mismatch / genetics. Carrier Proteins / genetics. Colorectal Neoplasms, Hereditary Nonpolyposis / genetics. Colorectal Neoplasms, Hereditary Nonpolyposis / pathology. Colorectal Neoplasms, Hereditary Nonpolyposis / radiotherapy. Disease Models, Animal. Disease Progression. Genes, Neoplasm / genetics. Immunohistochemistry / methods. Lymphoma / etiology. Mice. Mice, Knockout. Mutation / genetics. Neoplasm Proteins / analysis. Nuclear Proteins / deficiency. Nuclear Proteins / genetics. Radiotherapy / adverse effects. Receptors, Transforming Growth Factor beta / genetics. Thymus Neoplasms / etiology. Transforming Growth Factor beta / analysis. Transforming Growth Factor beta2. Tumor Suppressor Protein p53 / analysis. beta Catenin / analysis

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  • (PMID = 16623753.001).
  • [ISSN] 0959-9673
  • [Journal-full-title] International journal of experimental pathology
  • [ISO-abbreviation] Int J Exp Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Adaptor Proteins, Signal Transducing; 0 / Carrier Proteins; 0 / Mlh1 protein, mouse; 0 / Neoplasm Proteins; 0 / Nuclear Proteins; 0 / Receptors, Transforming Growth Factor beta; 0 / Transforming Growth Factor beta; 0 / Transforming Growth Factor beta2; 0 / Tumor Suppressor Protein p53; 0 / beta Catenin
  • [Other-IDs] NLM/ PMC2517356
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4
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4. Sung YM, Lee KS, Kim BT, Choi JY, Shim YM, Yi CA: 18F-FDG PET/CT of thymic epithelial tumors: usefulness for distinguishing and staging tumor subgroups. J Nucl Med; 2006 Oct;47(10):1628-34
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  • [Title] 18F-FDG PET/CT of thymic epithelial tumors: usefulness for distinguishing and staging tumor subgroups.
  • The purpose of our study was to assess the usefulness of integrated PET/CT using 18F-FDG for distinguishing thymic epithelial tumors according to the World Health Organization (WHO) classification.
  • METHODS: Thirty-three patients (age range, 34-68 y; mean age, 54.6 y) with thymic epithelial tumors, who underwent both integrated PET/CT and enhanced CT, were included.
  • The clinicopathologic stages, maximum standardized uptake values (SUVs), and uptake patterns of tumors on integrated PET/CT images, and various enhanced CT findings, are described according to the simplified (low-risk [types A, AB, and B1] and high-risk [types B2 and B3] thymomas and thymic carcinomas) subgroups of the WHO classification.
  • RESULTS: Tumors included 8 low-risk thymomas, 9 high-risk thymomas, and 16 thymic carcinomas.
  • The maximum SUVs of high-risk thymomas (P < 0.001) and low-risk thymomas (P < 0.001) were found to be significantly lower than those of thymic carcinomas.
  • Homogeneous 18F-FDG uptake within tumors was more frequently seen in thymic carcinomas than in high-risk thymomas (P = 0.027) or low-risk thymomas (P = 0.001).
  • CONCLUSION: Integrated PET/CT was found to be useful for differentiating subgroups of thymic epithelial tumors and for staging the extent of the disease.
  • [MeSH-major] Adenocarcinoma / diagnosis. Carcinoma, Squamous Cell / diagnosis. Fluorodeoxyglucose F18. Radiopharmaceuticals. Thymoma / diagnosis. Thymus Neoplasms / diagnosis

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  • (PMID = 17015898.001).
  • [ISSN] 0161-5505
  • [Journal-full-title] Journal of nuclear medicine : official publication, Society of Nuclear Medicine
  • [ISO-abbreviation] J. Nucl. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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45. Moorjani N, Khan O, Brown I, Singh N, Amer K: Synchronous thymoma and lung carcinoma resected via median sternotomy with VATS guidance. Thorac Cardiovasc Surg; 2007 Jun;55(4):271-2
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  • Synchronous tumours of the thymus and lung are rare.
  • We describe the case of a 57-year-old gentleman, who presented with a large type AB thymoma in the superior anterior mediastinum and a primary bronchogenic adenocarcinoma in the right upper lobe.
  • [MeSH-major] Adenocarcinoma / surgery. Lung Neoplasms / surgery. Neoplasms, Multiple Primary / surgery. Thoracic Surgery, Video-Assisted. Thymoma / surgery. Thymus Neoplasms / surgery

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  • (PMID = 17546563.001).
  • [ISSN] 0171-6425
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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46. Zhou P, Fang X, McNally BA, Yu P, Zhu M, Fu YX, Wang L, Liu Y, Zheng P: Targeting lymphotoxin-mediated negative selection to prevent prostate cancer in mice with genetic predisposition. Proc Natl Acad Sci U S A; 2009 Oct 6;106(40):17134-9
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  • To address this issue, we explored a non-antigen-based cancer immune prevention strategy using the transgenic adenocarcinoma of mouse prostate model that spontaneously develops prostate cancer with 100% penetrance.

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  • (PMID = 19805094.001).
  • [ISSN] 1091-6490
  • [Journal-full-title] Proceedings of the National Academy of Sciences of the United States of America
  • [ISO-abbreviation] Proc. Natl. Acad. Sci. U.S.A.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / R01 CA112001; United States / NCI NIH HHS / CA / R01 CA112001-04; United States / NCI NIH HHS / CA / R01 CA112001-03; United States / NCI NIH HHS / CA / CA112001-04; United States / NCI NIH HHS / CA / CA112001-03
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Immunoglobulin Fc Fragments; 0 / Lymphotoxin beta Receptor; 0 / Lymphotoxin-alpha; 0 / Receptors, Tumor Necrosis Factor, Member 25; 0 / Recombinant Fusion Proteins; 0 / Tnfrsf25 protein, mouse
  • [Other-IDs] NLM/ PMC2761305
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47. Kaplan-Lefko PJ, Sutherland BW, Evangelou AI, Hadsell DL, Barrios RJ, Foster BA, Demayo F, Greenberg NM: Enforced epithelial expression of IGF-1 causes hyperplastic prostate growth while negative selection is requisite for spontaneous metastogenesis. Oncogene; 2008 May 1;27(20):2868-76
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Expression of IGF-1(des) was sufficient to cause hyperplastic lesions in all mice, however the well-differentiated lesions did not progress to adenocarcinoma within a year.
  • [MeSH-minor] Adenocarcinoma / secondary. Animals. Brain Neoplasms / secondary. Cell Differentiation / physiology. Epithelium / metabolism. Epithelium / pathology. Heart Neoplasms / secondary. Humans. Liver Neoplasms / secondary. Lung Neoplasms / secondary. Male. Mice. Mice, Transgenic. Splenic Neoplasms / secondary. Thymus Neoplasms / secondary. Urologic Neoplasms / secondary


48. Carrio R, Lopez DM: Impaired thymopoiesis occurring during the thymic involution of tumor-bearing mice is associated with a down-regulation of the antiapoptotic proteins Bcl-XL and A1. Int J Mol Med; 2009 Jan;23(1):89-98
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Impaired thymopoiesis occurring during the thymic involution of tumor-bearing mice is associated with a down-regulation of the antiapoptotic proteins Bcl-XL and A1.
  • The thymus is a central lymphoid organ in which T lymphocytes undergo differentiation and maturation without the need for antigenic stimulation.
  • Thymic atrophy has been observed in several model systems, including aging, graft-vs-host-disease and tumor development.
  • We have previously shown that the progressive growth of D1-DMBA-3 mammary tumor leads to extreme thymic atrophy in the host.
  • This thymic involution is associated with an early block in T cell maturation at the triple negative stage of differentiation.
  • In the present study we have used our murine mammary tumor model to further analyze the specific T cell subpopulations present in the thymus of tumor-bearing animals as well as to characterize the alterations of the apoptotic process present during the impaired thymopoiesis associated to this thymic involution.
  • Together, our data suggest that the severe thymic involution seen in mammary tumor bearers is due to an arrest in at least two steps of T cell differentiation and a down-regulation of important molecules that control programmed cell death.
  • [MeSH-major] Down-Regulation. Gene Expression Regulation, Neoplastic. Proto-Oncogene Proteins / genetics. Thymus Gland / immunology. bcl-X Protein / genetics
  • [MeSH-minor] Adenocarcinoma / genetics. Adenocarcinoma / immunology. Animals. Apoptosis. Atrophy. Cell Dedifferentiation. Mammary Neoplasms, Experimental / genetics. Mammary Neoplasms, Experimental / immunology. Mice. Mice, Inbred BALB C. Proto-Oncogene Proteins c-bcl-2. T-Lymphocytes / cytology. T-Lymphocytes / immunology

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  • (PMID = 19082511.001).
  • [ISSN] 1107-3756
  • [Journal-full-title] International journal of molecular medicine
  • [ISO-abbreviation] Int. J. Mol. Med.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / R01 CA25583
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Bcl2l1 protein, mouse; 0 / Proto-Oncogene Proteins; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / bcl-X Protein; 114100-40-2 / Bcl2 protein, mouse
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49. Zhang L, Huang H, Wu K, Wang M, Wu B: Impact of BTG2 expression on proliferation and invasion of gastric cancer cells in vitro. Mol Biol Rep; 2010 Jul;37(6):2579-86
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  • BTG2 (B cell translocation gene 2) is downregulated in several human tumors and has been known as a tumor suppressor in carcinogenesis of thymus, prostate, kidney, and liver.
  • However, little is known about the role BTG2 plays in gastric adenocarcinoma.

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  • (PMID = 19728149.001).
  • [ISSN] 1573-4978
  • [Journal-full-title] Molecular biology reports
  • [ISO-abbreviation] Mol. Biol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Immediate-Early Proteins; 0 / Tumor Suppressor Proteins; 141490-22-4 / BTG2 protein, human
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50. Kanayama S, Matsuno A, Nagashima T, Ishida Y: Symptomatic pituitary metastasis of malignant thymoma. J Clin Neurosci; 2005 Nov;12(8):953-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Pituitary Neoplasms / secondary. Thymoma / secondary. Thymus Neoplasms / pathology
  • [MeSH-minor] Adenocarcinoma / pathology. Aged, 80 and over. Blepharoptosis / etiology. Humans. Magnetic Resonance Imaging. Male. Neoplasms, Multiple Primary / pathology. Stomach Neoplasms / pathology. Vision Disorders / etiology

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  • (PMID = 16326276.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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51. Seki E, Aoyama K, Ueda M, Haga T, Nakazato Y, Iijima M, Kojima M, Tanaka R: Mucinous adenocarcinoma of the thymus: a case report. J Thorac Oncol; 2008 Aug;3(8):935-7
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  • [Title] Mucinous adenocarcinoma of the thymus: a case report.
  • A mucinous adenocarcinoma of the thymus is rare, and there is presently limited information on the clinical aspects of this uncommon type of tumor.
  • Histologically the tumor consisted of a mucinous adenocarcinoma with pleural dissemination.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Thymus Neoplasms / pathology

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  • (PMID = 18670316.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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52. Liu Y, Chen T, Wong YS, Mei WJ, Huang XM, Yang F, Liu J, Zheng WJ: DNA binding and photocleavage properties and apoptosis-inducing activities of a ruthenium porphyrin complex [(Py-3')TPP-Ru(phen)2Cl]Cl and its heterometallic derivatives. Chem Biol Interact; 2010 Feb 12;183(3):349-56
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  • The interactions of a ruthenium porphyrin complex [(Py-3')TPP-Ru(phen)(2)Cl]Cl (phen=1,10-phenanthroline, (Py-3')TPP=5-(3'-pyridyl-10,15,20-triphenylporphyrin) (1) and its heterometallic derivatives, [Ni(Py-3')TPP-Ru(phen)(2)Cl][PF(6)] (2) and [Cu(Py-3')TPP-Ru(phen)(2)Cl][PF(6)] (3), with calf thymus DNA have been investigated by spectroscopic and viscosity measurements in this study.
  • As determined by MTT assay, the complexes were also identified as potent antiproliferative agents against A375 human melanoma cells, MCF-7 human breast adrenocarcinoma cells, Colo201 human colon adenocarcinoma cells and HepG2 human liver cancer cells.

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  • [Copyright] Copyright (c) 2009 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 19958751.001).
  • [ISSN] 1872-7786
  • [Journal-full-title] Chemico-biological interactions
  • [ISO-abbreviation] Chem. Biol. Interact.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / ((Py-3')TPP-Ru(phen)2Cl)Cl; 0 / (Cu(Py-3')TPP-Ru(phen)2Cl)(PF6); 0 / (Ni(Py-3')TPP-Ru(phen)2Cl)(PF6); 0 / Metalloporphyrins; 0 / Proto-Oncogene Proteins c-bcl-2; 9007-49-2 / DNA
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53. Sitić S, Mirt-Dabić M, Brcić L, Juros Z, Hutinec Z, Kruslin B: DNA ploidy in thymoma and associated multiple primary malignancies in the same patient. Acta Clin Croat; 2008 Sep;47(3):155-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Thymoma is an uncommon neoplasm derived from thymic epithelium.
  • Thymoma may be associated with different types of additional primary malignancies; however, colorectal adenocarcinoma and thyroid cancer appear to be most common.
  • [MeSH-major] DNA, Neoplasm / genetics. Neoplasms, Multiple Primary / genetics. Ploidies. Thymoma / genetics. Thymus Neoplasms / genetics

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  • (PMID = 19175064.001).
  • [ISSN] 0353-9466
  • [Journal-full-title] Acta clinica Croatica
  • [ISO-abbreviation] Acta Clin Croat
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Croatia
  • [Chemical-registry-number] 0 / DNA, Neoplasm
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54. Gao Z, Kahn L, Bhuiya T: Thymic carcinoid with mucinous stroma: a rare variant of carcinoid with an aggressive clinical course. Ann Diagn Pathol; 2006 Apr;10(2):114-6
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  • [Title] Thymic carcinoid with mucinous stroma: a rare variant of carcinoid with an aggressive clinical course.
  • One variant of thymic carcinoid has prominent mucinous stroma first reported in 1995.
  • We describe such a case characterized by abundant stromal mucin resulting in a histologic picture resembling of metastatic mucinous adenocarcinoma.
  • [MeSH-major] Adenocarcinoma, Mucinous / diagnosis. Adenocarcinoma, Mucinous / pathology. Carcinoid Tumor / pathology. Mediastinal Neoplasms / pathology. Mucins / metabolism. Thymus Neoplasms / pathology

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  • (PMID = 16546049.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Mucins
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55. Pantidou A, Kiziridou A, Antoniadis T, Tsilikas C, Destouni C: Mediastinum thymoma diagnosed by FNA and ThinPrep technique: a case report. Diagn Cytopathol; 2006 Jan;34(1):37-40
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  • Thymoma is a primary tumor of the thymus epithelial cells.
  • This is an interesting case of thymoma diagnosed by fine-needle aspiration biopsy (FNA) and ThinPrep technique, in a 54-year-old female patient with a history of gastric adenocarcinoma.
  • [MeSH-minor] Adenocarcinoma / pathology. Female. Histocytological Preparation Techniques. Humans. Middle Aged. Neoplasms, Second Primary / diagnosis. Stomach Neoplasms / pathology

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  • (PMID = 16355373.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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56. Kuriyama S, Ohashi R, Matsuda K, Sugano K, Muraki K, Minakata K, Ishiwata T, Hirama M, Kodama Y, Oh S, Suzuki K, Takahashi K: [Twelve cases of advanced thymic carcinoma: a clinical review]. Nihon Kokyuki Gakkai Zasshi; 2010 Aug;48(8):604-8
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  • [Title] [Twelve cases of advanced thymic carcinoma: a clinical review].
  • Thymic carcinoma is comparatively rare and no standard treatment has been established for advanced stage cases.
  • We reviewed our therapeutic experience in 12 cases of thymic carcinoma.
  • Nine cases were squamous cell carcinoma and 3 were adenocarcinoma.
  • The prognosis outcome of advanced thymic carcinoma is poor, but combined modality therapies such as surgery, chemotherapy and radiation can be effective for some advanced thymic carcinoma cases.
  • [MeSH-major] Adenocarcinoma / therapy. Carcinoma, Squamous Cell / therapy. Thymus Neoplasms / therapy

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  • (PMID = 20803979.001).
  • [ISSN] 1343-3490
  • [Journal-full-title] Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
  • [ISO-abbreviation] Nihon Kokyuki Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
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57. Sasmal PK, Saha S, Majumdar R, Dighe RR, Chakravarty AR: Photocytotoxic oxovanadium(IV) complexes showing light-induced DNA and protein cleavage activity. Inorg Chem; 2010 Feb 1;49(3):849-59
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  • The photocytotoxicity of complex 3 has been studied using adenocarcinoma A549 cells.
  • The complexes bind to calf thymus DNA giving binding constant values in the range of 6.6 x 10(4)-2.9 x 10(5) M(-1).
  • The dppz complex 3 also exhibits photocytotoxicity in non-small cell lung carcinoma/human lung adenocarcinoma A549 cells giving IC(50) value of 17 microM in visible light (IC(50) = 175 microM in dark).

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  • (PMID = 20039725.001).
  • [ISSN] 1520-510X
  • [Journal-full-title] Inorganic chemistry
  • [ISO-abbreviation] Inorg Chem
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Organometallic Compounds; 0 / Photosensitizing Agents; 0 / Serum Albumin, Bovine; 20644-97-7 / oxovanadium IV; 3WHH0066W5 / Vanadates; 9007-49-2 / DNA; 91080-16-9 / calf thymus DNA; EC 3.2.1.17 / Muramidase
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58. Feng L, Jia XB, Shi F, Chen Y: Identification of two polysaccharides from Prunella vulgaris L. and evaluation on their anti-lung adenocarcinoma activity. Molecules; 2010 Aug;15(8):5093-103
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  • [Title] Identification of two polysaccharides from Prunella vulgaris L. and evaluation on their anti-lung adenocarcinoma activity.
  • In order to evaluate polysaccharide P32's anti-lung adenocarcinoma activities and immunomodulation effects, a C57BL/6 mouse-Lewis lung carcinoma (LLC) model was established and investigated.
  • Our results showed that polysaccharides of PV had anti-lung cancer activity and could increase the thymus index and the spleen index in tumor-bearing mice, suggesting possible immunomodulation effects.
  • [MeSH-minor] Animals. Chromatography, Gas. Chromatography, High Pressure Liquid. Drug Screening Assays, Antitumor. Mice. Mice, Inbred C57BL. Molecular Weight. Phytotherapy. Reference Standards. Spectrophotometry, Ultraviolet. Spleen / drug effects. Spleen / pathology. Thymus Gland / drug effects. Thymus Gland / pathology. Time Factors

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  • (PMID = 20714287.001).
  • [ISSN] 1420-3049
  • [Journal-full-title] Molecules (Basel, Switzerland)
  • [ISO-abbreviation] Molecules
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Polysaccharides
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59. Okuda M, Huang CL, Haba R, Yokomise H: Clear cell carcinoma originating from ectopic thymus. Gen Thorac Cardiovasc Surg; 2009 May;57(5):269-71
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  • [Title] Clear cell carcinoma originating from ectopic thymus.
  • Ectopic thymus is not uncommon, but clear cell carcinoma originating from ectopic thymus has never been reported.
  • We report a case of clear cell carcinoma originating from ectopic thymus in which there was a good response to steroid-supplemented chemoradiotherapy.
  • [MeSH-major] Adenocarcinoma, Clear Cell / pathology. Choristoma / pathology. Mediastinal Neoplasms / pathology. Thymus Gland

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  • [Cites] Int J Pediatr Otorhinolaryngol. 1999 Jan 25;47(1):29-39 [10206392.001]
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  • (PMID = 19440827.001).
  • [ISSN] 1863-6705
  • [Journal-full-title] General thoracic and cardiovascular surgery
  • [ISO-abbreviation] Gen Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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60. Toda M, Hisano R, Yurugi H, Akita K, Maruyama K, Inoue M, Adachi T, Tsubata T, Nakada H: Ligation of tumour-produced mucins to CD22 dramatically impairs splenic marginal zone B-cells. Biochem J; 2009 Feb 1;417(3):673-83
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  • Mouse mammary adenocarcinoma cells, TA3-Ha, produce a mucin named epiglycanin, but a subline of them, TA3-St, does not.
  • It should be noted that splenic MZ (marginal zone) B-cells were dramatically reduced in the mice bearing TA3-Ha cells but not in those bearing TA3-St cells, this being consistent with the finding that the thymus-independent response was reduced in these mice.
  • [MeSH-major] Adenocarcinoma / metabolism. B-Lymphocytes / immunology. Mucins / metabolism. Sialic Acid Binding Ig-like Lectin 2 / metabolism. Spleen / immunology

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  • (PMID = 18925876.001).
  • [ISSN] 1470-8728
  • [Journal-full-title] The Biochemical journal
  • [ISO-abbreviation] Biochem. J.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, T-Independent; 0 / Membrane Glycoproteins; 0 / Mucins; 0 / Receptors, Antigen, B-Cell; 0 / Sialic Acid Binding Ig-like Lectin 2; 0 / epiglycanin protein, mouse
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61. Pettinari A, Amici M, Cuccioloni M, Angeletti M, Fioretti E, Eleuteri AM: Effect of polyphenolic compounds on the proteolytic activities of constitutive and immuno-proteasomes. Antioxid Redox Signal; 2006 Jan-Feb;8(1-2):121-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adenocarcinoma. Animals. Brain / enzymology. Catechin / analogs & derivatives. Catechin / pharmacology. Cattle. Cell Line, Tumor. Colonic Neoplasms. Gallic Acid / pharmacology. Humans. Oxidation-Reduction. Polyphenols. Thymus Gland / enzymology. Urokinase-Type Plasminogen Activator / antagonists & inhibitors

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  • (PMID = 16487045.001).
  • [ISSN] 1523-0864
  • [Journal-full-title] Antioxidants & redox signaling
  • [ISO-abbreviation] Antioxid. Redox Signal.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antioxidants; 0 / Flavonoids; 0 / Phenols; 0 / Polyphenols; 632XD903SP / Gallic Acid; 8R1V1STN48 / Catechin; BQM438CTEL / epigallocatechin gallate; EC 3.4.21.73 / Urokinase-Type Plasminogen Activator; EC 3.4.25.1 / Proteasome Endopeptidase Complex
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62. O'Gorman CS, Hamilton J, Rachmiel M, Gupta A, Ngan BY, Daneman D: Thyroid cancer in childhood: a retrospective review of childhood course. Thyroid; 2010 Apr;20(4):375-80
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  • Twenty-seven patients had metastases at presentation (19 lymph nodes only, 2 lung only, and 6 lymph node and distant) and 6 developed distant metastases during follow-up (3 lung, 2 thymus, and 1 paraspinal).
  • [MeSH-minor] Adenocarcinoma, Follicular / pathology. Adenocarcinoma, Follicular / surgery. Adolescent. Canada / epidemiology. Carcinoma, Papillary / pathology. Carcinoma, Papillary / surgery. Child. Female. Humans. Iodine Radioisotopes / therapeutic use. Lymphatic Metastasis. Male. Retrospective Studies. Thyroidectomy


63. Hansen EK, Krieg RM, Azar RJ, Jablons DM, Jahan TM, Zaloudek CJ: Unusual thoracic problems in patients with malignancies: case 3. Carcinoid tumor of the thymus. J Clin Oncol; 2005 Apr 20;23(12):2859-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unusual thoracic problems in patients with malignancies: case 3. Carcinoid tumor of the thymus.

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  • (PMID = 15838001.001).
  • [ISSN] 0732-183X
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA093708-01A3; United States / NCI NIH HHS / CA / R01 CA093708; United States / NCI NIH HHS / CA / R01 CA093708-01A3
  • [Publication-type] Journal Article
  • [Publication-country] United States
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64. Nakanishi T, Imaizumi K, Hasegawa Y, Kawabe T, Hashimoto N, Okamoto M, Shimokata K: Expression of macrophage-derived chemokine (MDC)/CCL22 in human lung cancer. Cancer Immunol Immunother; 2006 Nov;55(11):1320-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Ligands for CXCR3 chemokines [IFN-gamma-inducible protein of 10 kD (IP-10/CXCL10), monokine induced by IFN-gamma (Mig/CXCL9), IFN-inducible T cell alpha chemoattractant (I-TAC/CXCL11)] and those for CCR4 [macrophage-derived chemokine (MDC/CCL22), thymus- and activation-regulated chemokine (TARC/CCL17)] have been shown to play the central roles for T helper-cell recruitment into the tissues.
  • METHODS: Total RNA was prepared from lung cancer tissues of 40 patients (24 adenocarcinoma and 16 squamous cell carcinoma).
  • [MeSH-minor] Adenocarcinoma / metabolism. Aged. Biomarkers, Tumor / metabolism. Carcinoma, Squamous Cell / metabolism. Chemokine CCL22. Disease-Free Survival. Female. Humans. Male. Middle Aged. Recurrence

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  • (PMID = 16453150.001).
  • [ISSN] 0340-7004
  • [Journal-full-title] Cancer immunology, immunotherapy : CII
  • [ISO-abbreviation] Cancer Immunol. Immunother.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CCL22 protein, human; 0 / Chemokine CCL22; 0 / Chemokines, CC
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65. Srirajaskanthan R, Toubanakis C, Dusmet M, Caplin ME: A review of thymic tumours. Lung Cancer; 2008 Apr;60(1):4-13
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  • [Title] A review of thymic tumours.
  • Tumours of the thymus are uncommon and are generally regarded as being indolent.
  • Whilst this is often true of thymomas; thymic adenocarcinoma and thymic neuroendocrine cancer can be aggressive and have a poor prognosis.
  • The role for adjuvant therapy in both thymic carcinoma and thymoma is unclear except, in patients with stage I thymomas.
  • There is a high expression of somatostatin receptors in thymic tumours and anti-tumour benefit has been reported in patients treated with somatostatin analogues.
  • This has become an established therapy in management of gastroenteropancreatic neuroendocrine tumours and its use has been recently described in case reports in both thymoma and thymic carcinoma.
  • [MeSH-major] Thymus Neoplasms / therapy

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  • (PMID = 18343528.001).
  • [ISSN] 0169-5002
  • [Journal-full-title] Lung cancer (Amsterdam, Netherlands)
  • [ISO-abbreviation] Lung Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Ireland
  • [Number-of-references] 88
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66. Johnson EL, Singh R, Singh S, Johnson-Holiday CM, Grizzle WE, Partridge EE, Lillard JW Jr: CCL25-CCR9 interaction modulates ovarian cancer cell migration, metalloproteinase expression, and invasion. World J Surg Oncol; 2010 Jul 22;8:62
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  • Chemokine receptor CCR9 is primarily expressed by a small subset of immune cells and its only natural ligand, CCL25, is largely expressed in the thymus, which involutes with age.
  • Other than the thymus, CCL25 is expressed by the small bowel.
  • RESULTS: Our results show significantly (p<0.001) higher expression of CCR9 by mucinous adenocarcinoma, papillary serous carcinoma, and endometriod ovarian carcinoma cases, than compared to non-neoplastic ovarian tissue.

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  • (PMID = 20649989.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] ENG
  • [Grant] United States / NIMHD NIH HHS / MD / MD00525; United States / NCRR NIH HHS / RR / RR03034; United States / NIDDK NIH HHS / DK / DK58967; United States / NIGMS NIH HHS / GM / GM08248; United States / NCI NIH HHS / CA / CA086359; United States / NCI NIH HHS / CA / CA092078
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / CC chemokine receptor 9; 0 / CCL25 protein, human; 0 / Chemokines, CC; 0 / RNA, Messenger; 0 / Receptors, CCR; EC 3.4.- / Metalloproteases
  • [Other-IDs] NLM/ PMC2927595
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67. Ait M'barek L, Ait Mouse H, Jaâfari A, Aboufatima R, Benharref A, Kamal M, Bénard J, El Abbadi N, Bensalah M, Gamouh A, Chait A, Dalal A, Zyad A: Cytotoxic effect of essential oil of thyme (Thymus broussonettii) on the IGR-OV1 tumor cells resistant to chemotherapy. Braz J Med Biol Res; 2007 Nov;40(11):1537-44
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  • [Title] Cytotoxic effect of essential oil of thyme (Thymus broussonettii) on the IGR-OV1 tumor cells resistant to chemotherapy.
  • The anti-tumor effect of the Moroccan endemic thyme (Thymus broussonettii) essential oil (EOT) was investigated in vitro using the human ovarian adenocarcinoma IGR-OV1 parental cell line OV1/P and its chemoresistant counterparts OV1/adriamycin (OV1/ADR), OV1/vincristine (OV1/VCR), and OV1/cisplatin (OV1/CDDP).


68. Hansson M, Hermansson M, Svensson H, Elfvin A, Hansson LE, Johnsson E, Sjöling A, Quiding-Järbrink M: CCL28 is increased in human Helicobacter pylori-induced gastritis and mediates recruitment of gastric immunoglobulin A-secreting cells. Infect Immun; 2008 Jul;76(7):3304-11
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  • Human Helicobacter pylori infection gives rise to an active chronic gastritis and is a major risk factor for the development of duodenal ulcer disease and gastric adenocarcinoma.
  • To identify the signals for recruitment of gastric IgA-secreting cells, we investigated the gastric production of CCL28 (mucosa-associated epithelial chemokine) and CCL25 (thymus-expressed chemokine) in H. pylori-infected and uninfected individuals and the potential of gastric B-cell populations to migrate toward these chemokines.

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  • (PMID = 18426876.001).
  • [ISSN] 1098-5522
  • [Journal-full-title] Infection and immunity
  • [ISO-abbreviation] Infect. Immun.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CCL25 protein, human; 0 / CCL28 protein, human; 0 / Chemokines, CC; 0 / Immunoglobulin A, Secretory
  • [Other-IDs] NLM/ PMC2446710
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69. Tsuchida M, Umezu H, Hashimoto T, Shinohara H, Koike T, Hosaka Y, Eimoto T, Hayashi JI: Absence of gene mutations in KIT-positive thymic epithelial tumors. Lung Cancer; 2008 Dec;62(3):321-5
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  • [Title] Absence of gene mutations in KIT-positive thymic epithelial tumors.
  • However, the role of KIT expression in thymic carcinoma is not fully understood.
  • METHODS: Thymic epithelial tumors from 37 patients (17 thymic carcinomas and 20 thymomas) were examined.
  • RESULTS: KIT- and CD5-positive staining was observed only in thymic carcinoma.
  • Mutation analysis of the KIT gene was performed in 11 squamous cell carcinomas, 1 adenocarcinoma and 1 adenosquamous cell carcinoma.
  • CONCLUSIONS: Squamous cell carcinoma of the thymus frequently expressed KIT and CD5 proteins, whereas other tumors did not.
  • Unlike GIST, overexpression of KIT does not necessarily indicate gene mutation in thymic carcinoma.
  • KIT and CD5 appear useful for evaluating and subtyping thymic epithelial tumors.
  • [MeSH-major] Adenocarcinoma / genetics. Carcinoma, Adenosquamous / genetics. Carcinoma, Squamous Cell / genetics. Mutation / genetics. Proto-Oncogene Proteins c-kit / genetics. Thymoma / genetics. Thymus Neoplasms / genetics

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  • (PMID = 18486988.001).
  • [ISSN] 0169-5002
  • [Journal-full-title] Lung cancer (Amsterdam, Netherlands)
  • [ISO-abbreviation] Lung Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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70. Pastorino U, Yang XN, Francese M, Durkovic S, Biglioli P: Long-term survival after salvage surgery for invasive thymoma with intracardiac extension. Tumori; 2008 Sep-Oct;94(5):772-6
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  • [MeSH-major] Heart Neoplasms / secondary. Heart Neoplasms / surgery. Salvage Therapy / methods. Thymectomy. Thymoma / secondary. Thymoma / surgery. Thymus Neoplasms / pathology. Thymus Neoplasms / surgery
  • [MeSH-minor] Adenocarcinoma / surgery. Blood Vessel Prosthesis. Cardiac Surgical Procedures. Cardiopulmonary Bypass. Female. Heart Atria / pathology. Heart Atria / surgery. Humans. Lung Neoplasms / surgery. Middle Aged. Neoplasm Invasiveness. Neoplasms, Second Primary / surgery. Polytetrafluoroethylene. Tomography, X-Ray Computed. Treatment Outcome. Vascular Surgical Procedures / methods. Vena Cava, Superior / pathology. Vena Cava, Superior / surgery

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  • (PMID = 19112960.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 9002-84-0 / Polytetrafluoroethylene
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71. Dai ZK, Yu LM, Yang XS: [Anticancer effect of CL extract of Rosa roxburghii]. Zhongguo Zhong Yao Za Zhi; 2007 Jul;32(14):1453-7
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  • Cell toxicity of CL on human endometrial adenocarcinoma cell line JEC (JEC) cells was measured by MTT reduction test and growth curves drawing by trypan blue dye exclusion method.
  • RESULT: Comparing with the negative group, life span of EAC mice treated with CL was prolonged (P <0.05), and thymus index and spleen index of them were raised (P <0.05).
  • [MeSH-major] Adenocarcinoma / pathology. Antineoplastic Agents, Phytogenic / pharmacology. Drugs, Chinese Herbal / pharmacology. Endometrial Neoplasms / pathology. Rosa

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  • (PMID = 17966364.001).
  • [ISSN] 1001-5302
  • [Journal-full-title] Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  • [ISO-abbreviation] Zhongguo Zhong Yao Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; 0 / Drugs, Chinese Herbal; EC 1.1.1.27 / L-Lactate Dehydrogenase
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72. Petrella F, Leo F, Veronesi G, Solli P, Borri A, Galetta D, Gasparri R, Lembo R, Radice D, Scanagatta P, Spaggiari L: "Salvage" surgery for primary mediastinal malignancies: is it worthwhile? J Thorac Oncol; 2008 Jan;3(1):53-8
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  • Eleven patients suffered from thymic tumors (eight thymomas, three thymic carcinoma) whereas 10 patients suffered from nonthymic tumors (one lung adenocarcinoma + thymoma, two mediastinal monophasic sinovial sarcoma, one mediastinal neuroendocrine tumor, one mediastinal teratoblastoma, one mediastinal disgerminoma, one Hodgkin's lymphoma, one mediastinal atypic carcinoid, two medullary thyroid carcinoma).
  • Thymic neoplasms had a better prognosis (1-, 3-, and 5-year survival was 100, 87.5, 87.5%, respectively) when compared with others (1-, 3-, and 5-year survival was 77.8, 53.3, 26.7%, respectively--logrank p = 0.0128).
  • Thymic tumors obtain the best results in term of long-term survival.
  • [MeSH-minor] Adenocarcinoma / pathology. Adenocarcinoma / surgery. Adolescent. Adult. Aged. Carcinoid Tumor / pathology. Carcinoid Tumor / surgery. Dysgerminoma / pathology. Dysgerminoma / surgery. Female. Follow-Up Studies. Hodgkin Disease / pathology. Hodgkin Disease / surgery. Humans. Lung Neoplasms / pathology. Lung Neoplasms / surgery. Male. Middle Aged. Morbidity. Mortality. Neuroendocrine Tumors / pathology. Neuroendocrine Tumors / surgery. Retrospective Studies. Salvage Therapy / methods. Sarcoma / pathology. Sarcoma / surgery. Survival Analysis. Teratoma / pathology. Teratoma / surgery. Thymoma / pathology. Thymoma / surgery. Thymus Neoplasms / pathology. Thymus Neoplasms / surgery. Thyroid Neoplasms / pathology. Thyroid Neoplasms / surgery. Time Factors. Treatment Outcome

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  • (PMID = 18166841.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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73. Takahashi F, Tsuta K, Matsuno Y, Takahashi K, Toba M, Sato K, Uekusa T, Izumi H, Nakamura K, Hirose S, Fukuchi Y: Adenocarcinoma of the thymus: mucinous subtype. Hum Pathol; 2005 Feb;36(2):219-23
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  • [Title] Adenocarcinoma of the thymus: mucinous subtype.
  • Primary thymic adenocarcinoma, mucinous subtype, is extremely rare with only one case reported to date.
  • We describe herein a case of thymic mucinous adenocarcinoma.
  • A 59-year-old man was identified to have an anterior mediastinal tumor and was diagnosed as mucinous adenocarcinoma.
  • Collectively, the diagnosis of the tumor was primary mucinous adenocarcinoma of the thymus.
  • We propose that the mucinous subtype should be recognized as one of the histopathological entities of thymic adenocarcinoma.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Mediastinal Neoplasms / pathology. Thymus Neoplasms / pathology

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  • (PMID = 15754301.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / KRT7 protein, human; 0 / Keratin-7; 68238-35-7 / Keratins
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74. Ten Dam GB, Yamada S, Kobayashi F, Purushothaman A, van de Westerlo EM, Bulten J, Malmström A, Sugahara K, Massuger LF, van Kuppevelt TH: Dermatan sulfate domains defined by the novel antibody GD3A12, in normal tissues and ovarian adenocarcinomas. Histochem Cell Biol; 2009 Jul;132(1):117-27
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  • Differential expression of the DS epitopes recognized by antibodies GD3A12 and LKN1 (4/2,4 di-O-sulfated DS) was best seen in thymus and spleen, indicating differential expression of various DS domains in these organs.
  • [MeSH-major] Adenocarcinoma / metabolism. Antibodies / immunology. Dermatan Sulfate / metabolism. Ovarian Neoplasms / metabolism. Ovary / metabolism

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  • (PMID = 19360434.001).
  • [ISSN] 1432-119X
  • [Journal-full-title] Histochemistry and cell biology
  • [ISO-abbreviation] Histochem. Cell Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antibodies; 0 / Epitopes; 24967-94-0 / Dermatan Sulfate
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75. Hille A, Ott I, Kitanovic A, Kitanovic I, Alborzinia H, Lederer E, Wölfl S, Metzler-Nolte N, Schäfer S, Sheldrick WS, Bischof C, Schatzschneider U, Gust R: [N,N'-Bis(salicylidene)-1,2-phenylenediamine]metal complexes with cell death promoting properties. J Biol Inorg Chem; 2009 Jun;14(5):711-25
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-minor] Adenocarcinoma / drug therapy. Animals. Breast Neoplasms / drug therapy. Carcinoma / drug therapy. Cattle. Cell Line, Tumor. Circular Dichroism. Colonic Neoplasms / drug therapy. DNA / metabolism. Electric Impedance. Female. Humans. Oxidation-Reduction. Oxygen Consumption / drug effects. Reactive Oxygen Species / metabolism. Thymus Gland / metabolism

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  • (PMID = 19259708.001).
  • [ISSN] 1432-1327
  • [Journal-full-title] Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry
  • [ISO-abbreviation] J. Biol. Inorg. Chem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Chelating Agents; 0 / Metals; 0 / Reactive Oxygen Species; 0 / Salicylates; 118-57-0 / salophen; 9007-49-2 / DNA
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