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1. Moon YW, Rha SY, Shin SJ, Chang H, Shim HS, Roh JK: Adenocarcinoma of the small bowel at a single Korean institute: management and prognosticators. J Cancer Res Clin Oncol; 2010 Mar;136(3):387-94
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  • [Title] Adenocarcinoma of the small bowel at a single Korean institute: management and prognosticators.
  • PURPOSE: Small bowel adenocarcinoma (SBA) is a rare malignancy with a poor outcome.
  • RESULTS: The most common primary tumor site was the duodenum (82%).
  • CONCLUSIONS: Early diagnosis is crucial to improve outcomes of SBA with respect to increasing resectability.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma / therapy. Intestinal Neoplasms / diagnosis. Intestinal Neoplasms / therapy
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Algorithms. Chemotherapy, Adjuvant / methods. Chemotherapy, Adjuvant / utilization. Digestive System Surgical Procedures / methods. Female. Humans. Intestine, Small / pathology. Korea. Male. Middle Aged. Prognosis. Recurrence. Retrospective Studies. Treatment Outcome. Young Adult

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  • (PMID = 19760196.001).
  • [ISSN] 1432-1335
  • [Journal-full-title] Journal of cancer research and clinical oncology
  • [ISO-abbreviation] J. Cancer Res. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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2. Badía Bartolomé C, Díaz Formoso FJ, Rodríguez Falcón R, Marchena Gómez J: [Groove pancreatitis and its differential diagnosis with pancreatic adenocarcinoma]. Gastroenterol Hepatol; 2009 Jan;32(1):22-8
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  • [Title] [Groove pancreatitis and its differential diagnosis with pancreatic adenocarcinoma].
  • [Transliterated title] Pancreatitis del surco y su diagnóstico diferencial con el adenocarcinoma de páncreas.
  • We analyzed the clinical, radiographic and histologic characteristics, as well as the difficulties that arose in the differential diagnosis between groove pancreatitis (a benign entity consisting of a segmental form of chronic pancreatitis occurring as a sheet-like scar in the area of pancreatoduodenal groove) and adenocarcinoma of the pancreas.
  • To this end, four cases with abnormalities in the groove area were retrospectively reviewed, three with groove pancreatitis, and one with adenocarcinoma of the pancreas.
  • [MeSH-major] Adenocarcinoma / diagnosis. Duodenitis / diagnosis. Pancreatic Neoplasms / diagnosis. Pancreatitis / diagnosis
  • [MeSH-minor] Adult. Aged. Biopsy, Fine-Needle. Cholangiopancreatography, Endoscopic Retrograde. Cholangiopancreatography, Magnetic Resonance. Cholelithiasis / complications. Cholelithiasis / diagnosis. Chronic Disease. Diagnosis, Differential. Duodenum / pathology. Fatal Outcome. Humans. Intestinal Mucosa / pathology. Magnetic Resonance Imaging. Male. Middle Aged. Pancreaticoduodenectomy. Pancreatitis, Alcoholic / complications. Retrospective Studies

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  • [CommentIn] Gastroenterol Hepatol. 2009 Nov;32(9):662-3 [19525034.001]
  • (PMID = 19174095.001).
  • [ISSN] 0210-5705
  • [Journal-full-title] Gastroenterología y hepatología
  • [ISO-abbreviation] Gastroenterol Hepatol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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3. Lapikov IA, Mogilenko DA, Dizhe EB, Ignatovich IA, Orlov SV, Perevozchikov AP: [Ap1-like cis-elements in 5'-regulatory region of human apolipoprotein A-I gene]. Mol Biol (Mosk); 2008 Mar-Apr;42(2):295-305
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  • The functional role of 5'-apoA-I regions containing Ap1-like sites was studied in cotransfection experiments of HepG2 cells (synthesize endogenous ApoA-I), human duodenum adenocarcinoma Hutu80 cells (do not synthesize endogenous ApoA-I), human neuroblastoma SK-N-SH cells (do not synthesize endogenous A-I) with expression vectors of c-jun and mekk1 genes.

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  • (PMID = 18610838.001).
  • [ISSN] 0026-8984
  • [Journal-full-title] Molekuliarnaia biologiia
  • [ISO-abbreviation] Mol. Biol. (Mosk.)
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Russia (Federation)
  • [Chemical-registry-number] 0 / ATF2 protein, human; 0 / Activating Transcription Factor 2; 0 / Apolipoprotein A-I; 0 / Proto-Oncogene Proteins c-jun; 0 / Transcription Factor AP-1
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4. Hwang RF, Wang H, Lara A, Gomez H, Chang T, Sieffert N, Moon Y, Ram S, Zimmerman S, Lee JH, Pisters PW, Tamm EP, Fleming JB, Abbruzzese JL, Evans DB: Development of an integrated biospecimen bank and multidisciplinary clinical database for pancreatic cancer. Ann Surg Oncol; 2008 May;15(5):1356-66
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  • METHODS: A clinical database and PTB were created in 1990 and 2000, respectively, to collect clinical information and biospecimens from patients with suspected or confirmed pancreatic cancer, other pancreatic diseases, and tumors of the duodenum, ampulla of Vater, and distal bile duct.
  • The most common histologies of pancreatic tumors were pancreatic ductal adenocarcinoma (55.3%) and neuroendocrine carcinoma (16.3%).
  • The clinical database contains information for 7,647 patients with pancreatic cancer, other pancreatic disorders, and duodenal, ampullary, or bile duct neoplasms.

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  • (PMID = 18256882.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P20 CA101936; United States / NCI NIH HHS / CA / CA101936-01
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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5. Wakatsuki T, Irisawa A, Takagi T, Koyama Y, Hoshi S, Takenoshita S, Abe M, Ohira H: Primary adenocarcinoma of the minor duodenal papilla. Yonsei Med J; 2008 Apr 30;49(2):333-6
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  • [Title] Primary adenocarcinoma of the minor duodenal papilla.
  • Upper gastrointestinal endoscopy revealed a flat elevated tumor with central ulceration in the second portion of the duodenum.
  • Subsequent duodenoscopy for a more detailed examination showed that the tumor had originated in the minor duodenal papilla.
  • A biopsy specimen showed moderately differentiated adenocarcinoma.
  • Endoscopic retrograde pancreatography via the major duodenal papilla revealed a slightly dilated main pancreatic duct and obstruction of the accessory pancreatic duct.
  • Endoscopic ultrasonography showed a hypoechoic mass in the minor duodenal papilla with retention of the muscularis propria of the duodenum.
  • These findings suggest that the tumor existed only to a limited extent in the minor duodenal papilla, and that the tumor did not infiltrate into the pancreas.
  • For treatment, pylorus-preserving pancreatoduodenectomy was performed, and histological findings revealed a well-differentiated adenocarcinoma that originated in the minor duodenal papilla.
  • Primary adenocarcinoma of the minor duodenal papilla is extremely rare.
  • Our case is the first report of primary adenocarcinoma of the minor duodenal papilla at an early stage with no infiltration into muscularis propria of the duodenum and pancreas.
  • [MeSH-major] Adenocarcinoma / pathology. Pancreatic Ducts / pathology. Pancreatic Neoplasms / pathology

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  • (PMID = 18452274.001).
  • [ISSN] 0513-5796
  • [Journal-full-title] Yonsei medical journal
  • [ISO-abbreviation] Yonsei Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2615313
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6. Lee I, Lim JH, Choi D, Jang KT, Lee KT, Choi SH: Intraductal papillary mucinous tumors of the pancreas: branch duct tumor penetrating the stomach and duodenum. AJR Am J Roentgenol; 2006 Dec;187(6):W604-6
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  • [Title] Intraductal papillary mucinous tumors of the pancreas: branch duct tumor penetrating the stomach and duodenum.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Carcinoma, Papillary / pathology. Pancreatic Ducts / pathology. Pancreatic Neoplasms / pathology
  • [MeSH-minor] Duodenal Neoplasms / pathology. Humans. Male. Middle Aged. Neoplasm Invasiveness. Stomach Neoplasms / pathology

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  • (PMID = 17114512.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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7. Turzhitsky V, Liu Y, Hasabou N, Goldberg M, Roy HK, Backman V, Brand R: Investigating population risk factors of pancreatic cancer by evaluation of optical markers in the duodenal mucosa. Dis Markers; 2008;25(6):313-21
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  • [Title] Investigating population risk factors of pancreatic cancer by evaluation of optical markers in the duodenal mucosa.
  • The closest non-invasively accessible mucosa available for pancreatic cancer screening is the periampullary duodenal tissue.
  • In this study, we report a larger data set of low-coherence enhanced backscattering (LEBS) and elastic light scattering fingerprinting (ELF) optical markers from the periampullary duodenal mucosa.

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  • [ErratumIn] Dis Markers.2009;27(5):253
  • (PMID = 19208949.001).
  • [ISSN] 0278-0240
  • [Journal-full-title] Disease markers
  • [ISO-abbreviation] Dis. Markers
  • [Language] ENG
  • [Grant] United States / NIBIB NIH HHS / EB / R21 EB006742-01; United States / NCI NIH HHS / CA / CA112315-03; United States / NCI NIH HHS / CA / R01 CA112315; United States / NIBIB NIH HHS / EB / EB006742-01; United States / NIBIB NIH HHS / EB / R21 EB006742; United States / NCI NIH HHS / CA / R01 CA112315-03; United States / NIBIB NIH HHS / EB / EB003682-03; United States / NIBIB NIH HHS / EB / R01 EB003682-03; United States / NCI NIH HHS / CA / R01CA112315; United States / NIBIB NIH HHS / EB / R01 EB003682
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ NIHMS116351; NLM/ PMC2730822
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8. Lao-Sirieix P, Lovat L, Fitzgerald RC: Cyclin A immunocytology as a risk stratification tool for Barrett's esophagus surveillance. Clin Cancer Res; 2007 Jan 15;13(2 Pt 1):659-65
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  • EXPERIMENTAL DESIGN: A cross-sectional cyclin A immunostaining study was done in 77 patients attending for BE surveillance and 17 patients undergoing evaluation of esophageal adenocarcinoma.
  • The control tissues were as follows: 30 squamous esophagus, 20 gastric antrum, and 13 duodenum.
  • In the case-control cohort, patients with biopsies expressing cyclin A at the surface were more likely to progress to adenocarcinoma than those who did not (odds ratio, 7.5; 95% confidence interval, 1.8-30.7).
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma / metabolism. Barrett Esophagus / diagnosis. Barrett Esophagus / metabolism. Cyclin A / biosynthesis. Esophageal Neoplasms / diagnosis. Esophageal Neoplasms / metabolism. Gene Expression Regulation, Neoplastic


9. Yamamoto Y, Watanabe Y, Horiuchi A, Yoshida M, Yukumi S, Sato K, Nakagawa H, Sugishita H, Ishida N, Ishikawa M, Ishikawa K, Kawachi K: Adenoendocrine carcinoma of the accessory papilla of the duodenum: report of a case. Surg Today; 2009;39(5):425-9
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  • [Title] Adenoendocrine carcinoma of the accessory papilla of the duodenum: report of a case.
  • This report describes a very rare case of an adenoendocrine carcinoma of the accessory papilla of the duodenum.
  • Gastrointestinal endoscopy showed a protruding tumor with ulceration at the accessory papilla of the duodenum.
  • A biopsy revealed a small-cell carcinoma.
  • Microscopically, the tumor was a small-cell neuroendocrine carcinoma with adenomatous differentiation.
  • The final diagnosis was an adenoendocrine carcinoma with lymph node metastasis.
  • [MeSH-major] Adenocarcinoma, Papillary / diagnosis. Carcinoma, Neuroendocrine / diagnosis. Duodenal Neoplasms / diagnosis. Endocrine Glands / pathology

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  • (PMID = 19408082.001).
  • [ISSN] 1436-2813
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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10. Fischer CP, Bass B, Fahy B, Aloia T: Transampullary pancreatic duct stenting decreases pancreatic fistula rate following left pancreatectomy. Hepatogastroenterology; 2008 Jan-Feb;55(81):244-8
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  • Distal pancreatectomy was performed as the primary operation or as part of an en-bloc resection for a primary malignancy other than pancreatic adenocarcinoma.
  • A soft, pediatric feeding tube was inserted directly into the pancreatic duct and carefully fed into the duodenum (confirmed by palpation).
  • [MeSH-minor] Adenocarcinoma / surgery. Female. Humans. Intraoperative Period. Length of Stay. Ligation. Male. Middle Aged. Pancreatic Neoplasms / surgery

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  • (PMID = 18507117.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
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11. Liu ZF, Jiao SC, Yang JL, Dai GH: [Clinical research of 120 cases of primary small intestine malignant tumor]. Nan Fang Yi Ke Da Xue Xue Bao; 2010 Mar;30(3):602-4, 607
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  • [Title] [Clinical research of 120 cases of primary small intestine malignant tumor].
  • OBJECTIVE: To study the clinical and pathological features, diagnosis, therapy and prognosis of primary small intestine malignant tumor.
  • METHODS: A retrospective analysis was performed on the clinical data from the 120 cases of primary small intestine malignant tumor.
  • Most tumors originated in the duodenum (54.1%), and adenocarcinoma (55.8%) was the main pathological type.
  • CONCLUSION: Primary small intestine malignant tumors lack specific clinical manifestations and surgical resection should be performed as early as possible.
  • [MeSH-major] Adenocarcinoma. Intestinal Neoplasms / diagnosis. Intestinal Neoplasms / surgery. Intestine, Small / pathology

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  • (PMID = 20335150.001).
  • [ISSN] 1673-4254
  • [Journal-full-title] Nan fang yi ke da xue xue bao = Journal of Southern Medical University
  • [ISO-abbreviation] Nan Fang Yi Ke Da Xue Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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12. Mann CD, Thomasset SC, Johnson NA, Garcea G, Neal CP, Dennison AR, Berry DP: Combined biliary and gastric bypass procedures as effective palliation for unresectable malignant disease. ANZ J Surg; 2009 Jun;79(6):471-5
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  • [Title] Combined biliary and gastric bypass procedures as effective palliation for unresectable malignant disease.
  • BACKGROUND: Although endoscopic treatment of jaundice is increasingly used in the palliation of unresectable malignant disease, surgical bypass still has a role to play in this setting.
  • This study aimed to reappraise the short-term and long-term results of combined biliary/gastric bypass (hepaticojejunostomy and gastrojejunostomy) as palliation for unresectable malignant disease.
  • METHODS: All patients undergoing simultaneous biliary and gastric bypass procedures for unresectable malignant disease between August 2000 and January 2006 were identified and outcomes reviewed.
  • RESULTS: One hundred and two patients underwent open surgical biliary drainage procedures for palliation of malignant disease.
  • Underlying malignant disease included pancreatic carcinoma (n = 88), duodenal adenocarcinoma (n = 6) and distal cholangiocarcinoma (n = 3).
  • [MeSH-major] Biliary Tract Surgical Procedures / methods. Duodenal Neoplasms / surgery. Gastric Bypass / adverse effects. Gastrostomy. Jejunostomy. Pancreatic Neoplasms / surgery
  • [MeSH-minor] Adenocarcinoma / surgery. Adult. Aged. Aged, 80 and over. Cholangiocarcinoma / surgery. Female. Follow-Up Studies. Humans. Male. Middle Aged. Palliative Care / methods. Survival Rate. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 19566872.001).
  • [ISSN] 1445-2197
  • [Journal-full-title] ANZ journal of surgery
  • [ISO-abbreviation] ANZ J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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13. Alexander S, Bourke MJ, Williams SJ, Bailey A, Co J: EMR of large, sessile, sporadic nonampullary duodenal adenomas: technical aspects and long-term outcome (with videos). Gastrointest Endosc; 2009 Jan;69(1):66-73
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] EMR of large, sessile, sporadic nonampullary duodenal adenomas: technical aspects and long-term outcome (with videos).
  • Few studies have, however, been published on the safety, efficacy, and technical aspects of EMR in the duodenum.
  • OBJECTIVE: Our purpose was to evaluate the efficacy and safety of EMR of large (>15 mm) duodenal adenomas.
  • PATIENTS: Patients with large (>15 mm) sporadic nonampullary duodenal adenomas managed by a standardized technique who were referred by other specialist endoscopists for endoscopic treatment.
  • METHODS: Five-year data from patients undergoing EMR for large duodenal adenomas were reviewed retrospectively.
  • Post-EMR histologic examination revealed mucosal adenocarcinoma in 1, low-grade tubulovillous adenoma (TVA) in 16, high- or focal high-grade TVA in 3 patients, and 1 with both high-grade TVA and carcinoid.
  • CONCLUSION: EMR for large sporadic nonampullary duodenal adenomas is a safe and effective technique.
  • [MeSH-major] Adenoma / surgery. Duodenal Neoplasms / surgery. Duodenoscopy / methods. Intestinal Mucosa / surgery. Neoplasm Invasiveness / pathology
  • [MeSH-minor] Aged. Cohort Studies. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Staging. Retrospective Studies. Risk Assessment. Survival Rate. Time Factors. Treatment Outcome. Video-Assisted Surgery / methods

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  • (PMID = 18725157.001).
  • [ISSN] 1097-6779
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
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14. Iso Y, Sawada T, Rokkaku K, Shimoda M, Kubota K: Ball-valve gastric tumor associated with anomalous junction of the pancreatico-biliary ductal system and a right-sided round ligament: report of a case. Surg Today; 2008;38(5):458-62
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  • Gastroscopy revealed a bleeding polypoid gastric tumor in the anterior wall of the stomach, herniating into the duodenum (ball-valve syndrome), and a Bormann type-2 tumor in the posterior wall.
  • [MeSH-major] Adenocarcinoma / surgery. Digestive System Abnormalities / complications. Polyps / surgery. Stomach Neoplasms / surgery

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  • [Cites] Gastroenterol Jpn. 1977;12(4):293-304 [590702.001]
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  • (PMID = 18560972.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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15. Adhikari RC, Tuladhar A, Shrestha S, Sharma SK: Deep-seated thoracic and abdominal lesions: usefulness of ultrasound guided fine needle aspiration cytology, a 3 year experience. Nepal Med Coll J; 2010 Mar;12(1):20-5
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  • The aim of this study was to evaluate the overall utility of ultrasonographic guided FNAC in the diagnosis of abdominal and thoracic lesions.
  • In 264 cases (82.5%), FNAC was diagnostic with commonest diagnosis being malignant neoplasm (70.0%).
  • In liver, Metastatic adenocarcinoma is the commonest tumor, while in lung; the commonest lesion is non-small cell carcinoma.
  • Benign neoplasm (3.1%) and non neoplastic lesion (9.4%) were also diagnosed by FNAC.
  • Rare sites like oesophagus and duodenum were also aspirated.
  • [MeSH-major] Neoplasms / diagnosis. Ultrasonography, Interventional

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  • (PMID = 20677604.001).
  • [Journal-full-title] Nepal Medical College journal : NMCJ
  • [ISO-abbreviation] Nepal Med Coll J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nepal
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16. Chen KH, Mukaisho K, Sugihara H, Araki Y, Yamamoto G, Hattori T: High animal-fat intake changes the bile-acid composition of bile juice and enhances the development of Barrett's esophagus and esophageal adenocarcinoma in a rat duodenal-contents reflux model. Cancer Sci; 2007 Nov;98(11):1683-8
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  • [Title] High animal-fat intake changes the bile-acid composition of bile juice and enhances the development of Barrett's esophagus and esophageal adenocarcinoma in a rat duodenal-contents reflux model.
  • The dietary components responsible for the development of Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC) remain unclear.
  • Because only high cow-fat intake induced changes in the composition of bile acids in bile juice, we then selected animals fed with a low soybean-oil diet and those with a high cow-fat diet to carry out esophago-jejunostomy for reflux of the duodenal contents, and compared sequential morphological changes between these groups up to 30 weeks after surgery.
  • [MeSH-major] Adenocarcinoma / pathology. Barrett Esophagus / pathology. Bile / secretion. Bile Acids and Salts / chemistry. Dietary Fats / adverse effects. Duodenogastric Reflux / pathology. Duodenum / pathology. Esophageal Neoplasms / pathology. Gastrointestinal Contents / chemistry

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  • (PMID = 17868414.001).
  • [ISSN] 1349-7006
  • [Journal-full-title] Cancer science
  • [ISO-abbreviation] Cancer Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Bile Acids and Salts; 0 / Dietary Fats
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17. Kitami CE, Kurosaki I, Koyama Y, Makino H, Hatakeyama K: Long-term survival after hepatectomy for hepatic recurrence of carcinoma of the papilla of Vater. J Hepatobiliary Pancreat Surg; 2005;12(4):321-3
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  • Histologically, an exposed mass-forming type of tumor, measuring 40 x 30 mm, was composed of mucinous and papillary adenocarcinoma, invading into the muscularis propria of the duodenum, without lymph node metastases.
  • [MeSH-major] Adenocarcinoma, Mucinous / surgery. Adenocarcinoma, Papillary / surgery. Ampulla of Vater. Common Bile Duct Neoplasms / pathology. Hepatectomy. Liver Neoplasms / secondary. Liver Neoplasms / surgery

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  • (PMID = 16133701.001).
  • [ISSN] 0944-1166
  • [Journal-full-title] Journal of hepato-biliary-pancreatic surgery
  • [ISO-abbreviation] J Hepatobiliary Pancreat Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 1548R74NSZ / Tegafur; 56HH86ZVCT / Uracil; 1-UFT protocol
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18. Sabater L, Calvete J, Aparisi L, Cánovas R, Muñoz E, Añón R, Roselló S, Rodríguez E, Camps B, Alfonso R, Sala C, Sastre J, Cervantes A, Lledó S: [Pancreatic and periampullary tumors: morbidity, mortality, functional results and long-term survival]. Cir Esp; 2009 Sep;86(3):159-66
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  • [Transliterated title] Neoplasias de páncreas y periampulares: morbimortalidad, resultados funcionales y supervivencia a largo plazo.
  • Two and five-year survival rates in resected patients with pancreatic cancer were 42% and 9% respectively; in malignant ampulloma 71% and 53%; in mucinous adenocarcinomas 83% and 33%; in duodenal adenocarcinoma 100% and 75%; and in distal cholangiocarcinoma 50% and 50%.

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  • (PMID = 19616203.001).
  • [ISSN] 0009-739X
  • [Journal-full-title] Cirugía española
  • [ISO-abbreviation] Cir Esp
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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19. Kumar SP, Pavan Kumar A: Carcinoma in the fourth part of the duodenum. Can J Surg; 2009 Jun;52(3):E69-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Carcinoma in the fourth part of the duodenum.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma / surgery. Duodenal Neoplasms / diagnosis. Duodenal Neoplasms / surgery

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  • (PMID = 19503653.001).
  • [ISSN] 1488-2310
  • [Journal-full-title] Canadian journal of surgery. Journal canadien de chirurgie
  • [ISO-abbreviation] Can J Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC2689742
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20. Nakamura K, Higashi T, Yamada M, Imai K, Yamamoto Y: Basophilic intracytoplasmic viral matrix inclusions distributed widely in layer hens affected with avian-leukosis-virus-associated tumours. Avian Pathol; 2007 Feb;36(1):53-8
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  • Basopholic intracytoplasmic viral matrix inclusions (MIs) were widely distributed in the chickens affected with subcutaneous myxoma rhabdomyosarcoma, perineuroma, glioma, intra-abdominal adenocarcinoma, and nephroblastoma.
  • They were also present in the smooth muscle cells of the arteries in the spleen and lungs, in the smooth muscle of the digestive tract muscular layer (crop, oesophagus, proventriculus, gizzard, duodenum, jejunum, ileum, caecum, and large intestine), and in the smooth muscle of the capsule in the ovary and pancreas.
  • They consisted of electron-dense small granules and ring-shaped particles.

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  • (PMID = 17364510.001).
  • [ISSN] 0307-9457
  • [Journal-full-title] Avian pathology : journal of the W.V.P.A
  • [ISO-abbreviation] Avian Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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21. Toll AD, Bibbo M: Identification of gastrointestinal contamination in endoscopic ultrasound-guided pancreatic fine needle aspiration. Acta Cytol; 2010 May-Jun;54(3):245-8
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  • OBJECTIVE: To evaluate whether B72.3 and CEA could identify duodenal and gastric contamination in cell blocks of clinically proven cases of pancreatic ductal carcinoma, intraductal papillary mucinous neoplasm (IPMN) and mucinous cystic neoplasm (MCN).
  • STUDY DESIGN: Cell blocks of pancreatic fine needle aspirates from 19 ductal adenocarcinomas, 9 IPMNs, 5 MCNs, and 22 cases containing gastrointestinal epithelial contamination (GIC) (7 gastric, 15 duodenal) were stained with antibody to carcinoembryonic antigen (CEA) and B72.3.
  • It was never expressed in gastric contamination and was positive in 2/15 (13%) duodenal contaminants.
  • It was positive in 2/7 (28%) gastric and 7/15 (47%) duodenal contaminants.
  • A lack of CEA expression, however, can be used to identify both gastric and duodenal contamination.
  • [MeSH-major] Duodenum / pathology. Endosonography. Pancreatic Neoplasms / diagnosis. Stomach / pathology
  • [MeSH-minor] Adenocarcinoma, Mucinous / diagnosis. Adenocarcinoma, Mucinous / metabolism. Antibodies, Neoplasm / metabolism. Artifacts. Biomarkers / metabolism. Biopsy, Fine-Needle. Carcinoembryonic Antigen / metabolism. Carcinoma, Pancreatic Ductal / diagnosis. Carcinoma, Pancreatic Ductal / metabolism. Carcinoma, Papillary / diagnosis. Carcinoma, Papillary / metabolism. Diagnostic Errors / prevention & control. Humans

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  • (PMID = 20518405.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Neoplasm; 0 / B72.3 antibody; 0 / Biomarkers; 0 / Carcinoembryonic Antigen
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22. Nakanishi Y, Ito T, Kubota K, Takeda H, Yonemori A, Kawakami H, Zen Y, Kondo S: Spindle cell-type undifferentiated carcinoma of the common bile duct of the hepatic hilus: report of a case. Surg Today; 2007;37(8):708-12
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  • Computed tomography showed the tumor to measure 15 x 12 mm in the hepatic hilus, with the obliteration of the right to main trunk of the portal vein and a swollen lymph node in the hepato-duodenum ligament.
  • However, a permanent section revealed both spindle cells and poorly differentiated tubular adenocarcinoma cells positive for CAM5.2, AE1/AE3, and vimentin.

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  • (PMID = 17643221.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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23. Jerkic S, Rosewich H, Scharf JG, Perske C, Füzesi L, Wilichowski E, Gärtner J: Colorectal cancer in two pre-teenage siblings with familial adenomatous polyposis. Eur J Pediatr; 2005 May;164(5):306-10
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  • Familial adenomatous polyposis (FAP) is an autosomal dominant disorder that characteristically presents with colon cancer in early adult life.
  • Oesophago-gastric and duodenal endoscopy revealed that polyps had also developed in the duodenum.
  • The patient underwent a proctocolectomy and endoscopic duodenal mucosectomy.
  • The diagnosis of an adenocarcinoma of the colon and further adenomatous polyps with low-grade and high-grade dysplasia was confirmed by histology.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenomatous Polyposis Coli / diagnosis. Carcinoma / diagnosis. Colorectal Neoplasms / diagnosis. Siblings


24. Riall TS, Cameron JL, Lillemoe KD, Campbell KA, Sauter PK, Coleman J, Abrams RA, Laheru D, Hruban RH, Yeo CJ: Pancreaticoduodenectomy with or without distal gastrectomy and extended retroperitoneal lymphadenectomy for periampullary adenocarcinoma--part 3: update on 5-year survival. J Gastrointest Surg; 2005 Dec;9(9):1191-204; discussion 1204-6
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  • [Title] Pancreaticoduodenectomy with or without distal gastrectomy and extended retroperitoneal lymphadenectomy for periampullary adenocarcinoma--part 3: update on 5-year survival.
  • The study objective was to update the survival analysis at the 5-year mark of patients undergoing standard versus radical (extended) pancreaticoduodenectomy (PD) for periampullary adenocarcinoma (cancers of the pancreas, ampulla, common bile duct, and duodenum).
  • Five patients were excluded from final analysis because final pathology failed to reveal adenocarcinoma.
  • For pancreatic adenocarcinoma patients, the 1- and 5-year survival rates in the standard group were 75% and 13%, respectively, compared with 73% and 29% in the radical group (P = 0.13).
  • The increased morbidity rate, longer operative time, and similar survival for radical PD led us to conclude that pylorus-preserving PD without retroperitoneal lymphadenectomy should be the procedure of choice for most patients with resectable periampullary adenocarcinoma.
  • While there is an intriguing trend toward improved survival in patients with pancreatic adenocarcinoma in the radical group, this trend may be largely accounted for by the higher incidence of microscopically margin positive resections in the standard resection group (21%) compared with a 5% incidence in the radical group (P = 0.002).
  • [MeSH-major] Adenocarcinoma / surgery. Ampulla of Vater. Common Bile Duct Neoplasms / surgery. Gastrectomy / methods. Lymph Node Excision / methods. Pancreaticoduodenectomy / methods

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  • (PMID = 16332474.001).
  • [ISSN] 1091-255X
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial
  • [Publication-country] United States
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25. Membrillo-Romero A, Hernández-Mondragón O, Blancas-Valencia JM: [Images of gastrointestinal endoscopy. Duodenal Adenocarcinoma (fourth segment)]. Rev Med Inst Mex Seguro Soc; 2006 May-Jun;44(3):256
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  • [Title] [Images of gastrointestinal endoscopy. Duodenal Adenocarcinoma (fourth segment)].
  • [Transliterated title] Imágenes de endoscopia gastrointestinal. Adenocarcinoma duodenal (cuarta porción).
  • [MeSH-major] Adenocarcinoma / diagnosis. Duodenal Neoplasms / diagnosis. Endoscopy, Gastrointestinal

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  • (PMID = 16870121.001).
  • [ISSN] 0443-5117
  • [Journal-full-title] Revista médica del Instituto Mexicano del Seguro Social
  • [ISO-abbreviation] Rev Med Inst Mex Seguro Soc
  • [Language] spa
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Mexico
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26. Moon YL, Ahn KY, Moon SP, Lim SC, Venkat G: Subscapularis muscle metastases of duodenal adenocarcinoma: a case report. J Shoulder Elbow Surg; 2010 Mar;19(2):e18-21
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  • [Title] Subscapularis muscle metastases of duodenal adenocarcinoma: a case report.

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  • (PMID = 19963402.001).
  • [ISSN] 1532-6500
  • [Journal-full-title] Journal of shoulder and elbow surgery
  • [ISO-abbreviation] J Shoulder Elbow Surg
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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27. Avenel P, McKendrick A, Silapaswan S, Kolachalam R, Kestenberg W, Ferguson L, Jacobs MJ, Goriel Y, Mittal V: Gastrointestinal carcinoids: an increasing incidence of rectal distribution. Am Surg; 2010 Jul;76(7):759-63
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  • Other sites of carcinoid tumors were the appendix (8.3%), colon (8.3%), and duodenum (3.8%).
  • CT was not helpful in preoperative diagnosis of carcinoid tumor.
  • Fifteen patients died in follow-up with eight deaths related to carcinoid tumors, in the small bowel (6), rectum (1), and colon (1).
  • Most of the deaths occurred in patients with carcinoid syndrome, synchronous malignancy, and malignant carcinoid tumors.
  • Screening colonoscopy, in addition to decreasing colorectal adenocarcinoma mortality, is useful in diagnosing carcinoid tumors at an earlier stage and in decreasing mortality from malignant colorectal carcinoid tumors.

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  • (PMID = 20698387.001).
  • [ISSN] 0003-1348
  • [Journal-full-title] The American surgeon
  • [ISO-abbreviation] Am Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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28. Bach P, Möhring C, Krawzak HW, Goepel M: [Retroperitoneal extravasation as the primary symptom of a pancreatic carcinoma]. Urologe A; 2007 Nov;46(11):1548-50
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  • Adenocarcinoma of the pancreas has a low 5-year survival rate of approximately 5%.
  • In particular, individuals suffering from carcinomas located within the pancreatic tail are at high risk of a missed diagnosis.
  • An adenocarcinoma of the pancreatic tail was diagnosed in this case report based on a large retroperitoneal extravasation missing further symptoms.
  • [MeSH-major] Adenocarcinoma, Mucinous / diagnostic imaging. Extravasation of Diagnostic and Therapeutic Materials / diagnostic imaging. Pancreatic Neoplasms / diagnostic imaging
  • [MeSH-minor] Aorta, Abdominal / pathology. Diagnosis, Differential. Duodenum / pathology. Gastroenterostomy. Humans. Male. Middle Aged. Neoplasm Invasiveness / pathology. Neoplasm Staging. Palliative Care. Retroperitoneal Space / diagnostic imaging. Tomography, X-Ray Computed. Ureter / pathology. Urinoma / diagnostic imaging. Urography

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  • [Cites] Hinyokika Kiyo. 1998 Nov;44(11):809-11 [9893227.001]
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  • (PMID = 17786402.001).
  • [ISSN] 0340-2592
  • [Journal-full-title] Der Urologe. Ausg. A
  • [ISO-abbreviation] Urologe A
  • [Language] ger
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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29. Scatton O, Sauvanet A, Cazals-Hatem D, Vullierme MP, Ruszniewski P, Belghiti J: Dorsal pancreatectomy: an embryology-based resection. J Gastrointest Surg; 2006 Mar;10(3):434-8
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  • In a 45-year-old man with acute pancreatitis and recent onset of diabetes mellitus, intraductal papillary mucinous neoplasm (IPMN) associated with pancreas divisum was found.
  • Resection of only the dorsal pancreas was performed with division of the pancreas at the internal side of the duodenum and at the anterior edge of the common bile duct.
  • The gastroduodenal artery was preserved resulting in good vascularization of both common bile duct and proximal duodenum.
  • [MeSH-major] Adenocarcinoma, Mucinous / surgery. Carcinoma, Pancreatic Ductal / surgery. Pancreas / abnormalities. Pancreatectomy / methods

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  • [Cites] Ann Surg. 2004 Jun;239(6):788-97; discussion 797-9 [15166958.001]
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  • (PMID = 16504892.001).
  • [ISSN] 1091-255X
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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31. Pricop C, Lefter LP, Scripcariu V, Danciu M, Buleu D, Dragomir C: [Metachronous primary cancers of the colon and stomach]. Rev Med Chir Soc Med Nat Iasi; 2005 Oct-Dec;109(4):817-21
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  • We report herein a case of 69 years old woman who, in the course of 11 years, developed two cancers: carcinoma of the colon fistulization in duodenum and adenocarcinoma of the stomach.
  • A decade later, she suffered a total gastrectomy with distal pancreatectomy for gastric adenocarcinoma.
  • Although patients with primary multiple cancers are not common, it is nonetheless important for clinicians to consider the possibility of metachronous cancers in patients who were treated for a primary malignant tumor.
  • [MeSH-major] Adenocarcinoma / surgery. Carcinoma / surgery. Colonic Neoplasms / surgery. Neoplasms, Multiple Primary / surgery. Neoplasms, Second Primary / surgery. Stomach Neoplasms / surgery

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  • (PMID = 16610181.001).
  • [ISSN] 0048-7848
  • [Journal-full-title] Revista medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti din Iaş̧i
  • [ISO-abbreviation] Rev Med Chir Soc Med Nat Iasi
  • [Language] rum
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Romania
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32. Koizumi M, Sata N, Yoshizawa K, Kurihara K, Yasuda Y: Carcinoma Arising from Brunner's Gland in the Duodenum after 17 Years of Observation - A Case Report and Literature Review. Case Rep Gastroenterol; 2007;1(1):103-9
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  • [Title] Carcinoma Arising from Brunner's Gland in the Duodenum after 17 Years of Observation - A Case Report and Literature Review.
  • Esophagogastroduodenoscopy (EGD) detected a small protruding lesion in the duodenal bulb, which was diagnosed as Brunner's adenoma.
  • The lesion had changed shape to become a 10 mm sessile tumor with a central depression, and following a biopsy was diagnosed as an adenocarcinoma.
  • The patient underwent partial resection of the duodenum.
  • This is an extremely rare case of primary duodenal carcinoma arising from Brunner's gland in a patient observed for 17 years.

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  • (PMID = 21487554.001).
  • [ISSN] 1662-0631
  • [Journal-full-title] Case reports in gastroenterology
  • [ISO-abbreviation] Case Rep Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Other-IDs] NLM/ PMC3073796
  • [Keywords] NOTNLM ; Adenocarcinoma / Brunner's gland / Duodenal cancer
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33. Jiménez Rodríguez RM, Suárez Artacho G, Morcillo J, Díaz Pavón JM, Morales Méndez S: [Adenocarcinoma in the fourth portion of duodenum in a patient with familial adenomatous polyposis]. Rev Esp Enferm Dig; 2007 Aug;99(8):477-8
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  • [Title] [Adenocarcinoma in the fourth portion of duodenum in a patient with familial adenomatous polyposis].
  • [Transliterated title] Adenocarcinoma de cuarta porción de duodeno en paciente con poliposis adenomatosa familiar.
  • [MeSH-major] Adenocarcinoma. Adenomatous Polyposis Coli. Duodenal Neoplasms. Neoplasms, Second Primary


34. Tsuchida K, Morinaga S, Sugano N, Shiozawa M, Akaike M, Sugimasa Y, Takemiya S, Hayashi H, Rino Y, Imada T: [A case of flat elevated type carcinoma in adenoma of the duodenum with gastric cancer]. Gan To Kagaku Ryoho; 2006 Nov;33(12):1878-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of flat elevated type carcinoma in adenoma of the duodenum with gastric cancer].
  • Duodenal adenoma is rare, and there have been very few case reports of flat elevated type adenoma.
  • We report a case of flat elevated type carcinoma in adenoma of the duodenum with gastric cancer.
  • Endoscopic examination revealed the gastric cancer and a flat elevated tumor in the descending part of the duodenum, measuring 6 cm in diameter.
  • The biopsy specimen of the duodenal lesion was diagnosed as adenoma.
  • Distal gastrectomy and segmental partial resection of the duodenum were performed with no complication.
  • Histologically, the gastric cancer was poorly differentiated adenocarcinoma with submcosal invasion and without lymph node metastasis, and the duodenal tumor was a well differentiated carcinoma in villous adenoma.
  • The duodenal adenocarcinoma was limited to the mucosal layer and the resected margins were free of tumor.
  • It is difficult to distinguish a carcinoma from a benign elevated lesion in the duodenum.
  • [MeSH-major] Adenocarcinoma / pathology. Adenoma, Villous / pathology. Carcinoma / pathology. Duodenal Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Stomach Neoplasms / pathology

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  • (PMID = 17212134.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 4
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35. Green PH, Cellier C: Celiac disease. N Engl J Med; 2007 Oct 25;357(17):1731-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Celiac Disease / diagnosis. Celiac Disease / diet therapy. Duodenum / pathology
  • [MeSH-minor] Adenocarcinoma / etiology. Autoimmune Diseases / diagnosis. Autoimmune Diseases / diet therapy. Biopsy. Duodenoscopy. Glutens / administration & dosage. HLA-DQ Antigens / analysis. Humans. Immunoglobulin A / blood. Intestinal Neoplasms / etiology. Lymphoma, T-Cell / etiology

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  • [CommentIn] N Engl J Med. 2008 Feb 14;358(7):747-8; author reply 748-9 [18283723.001]
  • [CommentIn] N Engl J Med. 2008 Feb 14;358(7):747; author reply 748-9 [18283724.001]
  • [CommentIn] N Engl J Med. 2008 Feb 14;358(7):747; author reply 748-9 [18272902.001]
  • (PMID = 17960014.001).
  • [ISSN] 1533-4406
  • [Journal-full-title] The New England journal of medicine
  • [ISO-abbreviation] N. Engl. J. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / HLA-DQ Antigens; 0 / HLA-DQ2 antigen; 0 / HLA-DQ8 antigen; 0 / Immunoglobulin A; 8002-80-0 / Glutens
  • [Number-of-references] 108
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36. Aranha GV, Shoup M: Nonstandard pancreatic resections for unusual lesions. Am J Surg; 2005 Feb;189(2):223-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Pancreatic resections including pancreaticoduodenectomy and distal pancreatectomy are the standard of care for patients with malignant tumors of the pancreas.
  • RESULTS: Parenchymal-sparing surgeries including pancreatic enucleation, central pancreatectomy, splenic-preserving distal pancreatectomy, and duodenal-preserving pancreatic head resection are described.
  • [MeSH-major] Adenocarcinoma / surgery. Pancreatectomy / methods. Pancreatic Neoplasms / surgery. Pancreaticoduodenectomy / methods
  • [MeSH-minor] Duodenum / surgery. Humans. Spleen / surgery

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  • (PMID = 15720996.001).
  • [ISSN] 0002-9610
  • [Journal-full-title] American journal of surgery
  • [ISO-abbreviation] Am. J. Surg.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 52
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37. Abbass R, Rigaux J, Al-Kawas FH: Nonampullary duodenal polyps: characteristics and endoscopic management. Gastrointest Endosc; 2010 Apr;71(4):754-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nonampullary duodenal polyps: characteristics and endoscopic management.
  • BACKGROUND: Guidelines for endoscopic resection and surveillance of nonampullary duodenal (NAD) polyps are still not well-defined.
  • Most lesions were sessile, solitary, and located in the descending duodenum.
  • Colon adenomas were found in 53% of patients with duodenal adenomas.
  • CONCLUSION: NAD polyps were large, sessile, and more commonly found in the second portion of the duodenum.
  • [MeSH-major] Duodenal Neoplasms / surgery. Duodenoscopy / methods. Intestinal Polyps / surgery
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / pathology. Adenocarcinoma / surgery. Adenoma / diagnosis. Adenoma / pathology. Adenoma / surgery. Biopsy. Carcinoid Tumor / diagnosis. Carcinoid Tumor / pathology. Carcinoid Tumor / surgery. Duodenum / pathology. Duodenum / surgery. Equipment Design. Follow-Up Studies. Humans. Hyperplasia. Intestinal Mucosa / pathology. Intestinal Mucosa / surgery. Laser Therapy. Lasers, Gas. Lipoma / diagnosis. Lipoma / pathology. Lipoma / surgery. Neoplasms, Multiple Primary / diagnosis. Neoplasms, Multiple Primary / pathology. Neoplasms, Multiple Primary / surgery. Retrospective Studies

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  • [Copyright] Copyright 2010 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved.
  • (PMID = 20363416.001).
  • [ISSN] 1097-6779
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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38. Terada T: Primary Pure Squamous Cell Carcinoma of the Duodenum: A Case Report. Gastroenterology Res; 2010 Feb;3(1):39-40
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  • [Title] Primary Pure Squamous Cell Carcinoma of the Duodenum: A Case Report.
  • : Only two cases of squamous cell carcinoma of the duodenum have been reported in the literature.
  • The author herein reports a case of squamous cell carcinoma of the duodenum.
  • An endoscopic examination revealed a duodenal tumor.
  • The tumor was circumferential elevated one with duodenal obstruction, and located in the descending part near and distal to the ampulla of Vater.
  • Imaging modalities also detected the duodenal tumor, but did not show tumors of other locations including the pancreas.
  • The duodenal tumor was different from ampullary tumor and pancreatic tumor.
  • Six biopsies were obtained from the duodenal tumor.
  • All the six biopsies showed malignant cells arranged in a medullary pattern.
  • The malignant cells showed hyperchromatic nuclei, and mitotic figures were scattered.
  • The pathologic features were interpreted as a squamous cell carcinoma of the duodenum.
  • The carcinoma was pure squamous cell carcinoma without differentiation into adenocarcinoma or endocrine carcinoma.

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  • (PMID = 27956983.001).
  • [ISSN] 1918-2805
  • [Journal-full-title] Gastroenterology research
  • [ISO-abbreviation] Gastroenterology Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
  • [Keywords] NOTNLM ; Duodenum / Histopathology / Squamous cell carcinoma
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39. Hiki N, Fukunaga T, Tokunaga M, Ohyama S, Yamada K, Saiura A, Yamaguchi T: An effective duodenum bulb mobilization for extracorporeal Billroth I anastomosis of laparoscopic gastrectomy. J Gastrointest Surg; 2009 Feb;13(2):230-5
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  • [Title] An effective duodenum bulb mobilization for extracorporeal Billroth I anastomosis of laparoscopic gastrectomy.
  • BACKGROUND DATA: Extracorporeal circular-stapled Billroth I (B-I) anastomosis is difficult in patients with obesity, a large body shape, or small remnant stomach, as it requires the duodenal stump to be lifted outside of the wound.
  • The aim of this study was to evaluate the feasibility of circular-stapled B-I reconstruction for laparoscopy-assisted distal gastrectomy (LADG) with effective duodenal mobilization.
  • The greater omentum, comprised of four membrane layers, was completely dissected for effective duodenal bulb mobilization to allow easy performance of extracorporeal end-to-end gastroduodenostomy.
  • CONCLUSIONS: Feasible duodenal bulb mobilization by complete dissection of the greater omentum allows easy performance of extracorporeal B-I anastomosis and minimizes complications related to anastomosis in LADG.
  • [MeSH-major] Adenocarcinoma / surgery. Gastrectomy. Gastroenterostomy / methods. Laparoscopy. Stomach Neoplasms / surgery. Surgical Stapling / methods
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Body Mass Index. Cohort Studies. Duodenum / surgery. Feasibility Studies. Female. Humans. Male. Middle Aged. Retrospective Studies. Treatment Outcome

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  • (PMID = 18795375.001).
  • [ISSN] 1873-4626
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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41. Yamasaki T, Nebiki H, Sasaki E, Kurai O: Successful treatment of duodenal adenocarcinoma with multiple liver metastases by S-1 + irinotecan (CPT-11). Clin J Gastroenterol; 2009 Aug;2(4):287-290
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Successful treatment of duodenal adenocarcinoma with multiple liver metastases by S-1 + irinotecan (CPT-11).
  • Unresectable duodenal adenocarcinoma excluding the ampullary region is rare, and no standard chemotherapy has been defined for this disease.
  • Although S-1-based chemotherapy is widely administered for advanced gastric cancer, few reports have described advanced duodenal cancer treated with S-1-based chemotherapy.
  • We present herein a case of duodenal adenocarcinoma with liver metastases.
  • Gastroduodenal endoscopy revealed an ulcerative lesion on the upper wall of the duodenal bulb, and biopsy specimens showed well-differentiated adenocarcinoma.
  • S-1-based regimens appear effective and well tolerated, and S-1 may thus represent a useful option for advanced duodenal cancer.

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  • (PMID = 26192427.001).
  • [ISSN] 1865-7257
  • [Journal-full-title] Clinical journal of gastroenterology
  • [ISO-abbreviation] Clin J Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Keywords] NOTNLM ; Chemotherapy / Duodenal cancer / Irinotecan / Liver metastases / S-1
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42. Cienfuegos JA, Baixauli J, Zozaya G, Bueno A, Arredondo J, Regueira FM, Angós R, Hernández-Lizoáin JL, Idoate MA: Peutz-Jeghers syndrome and duodeno-jejunal adenocarcinoma--therapeutic implications. Rev Esp Enferm Dig; 2009 Dec;101(12):875-9
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  • [Title] Peutz-Jeghers syndrome and duodeno-jejunal adenocarcinoma--therapeutic implications.
  • Hemminki in 1997 described the presence of LKB-1 mutation tumor-suppressor gen.The patients with PJS develop a higher cumulative incidence of gastrointestinal, pancreas and extraintestinal tumors, being occasion of a renew interest on hamartomatous polyposis syndromes regarding the clinical care, cancer surveillance treatment and long term follow-up.We report the case of a 38 years old male, diagnosed of PJS who developed a multiple adenocarcinoma in duodenum and yeyunum.
  • [MeSH-major] Adenocarcinoma. Duodenal Neoplasms. Jejunal Neoplasms. Neoplasms, Multiple Primary. Peutz-Jeghers Syndrome / complications
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Disease-Free Survival. Female. Follow-Up Studies. Humans. Infant. Infant, Newborn. Male. Neoplasm Invasiveness / pathology. Pancreaticoduodenectomy. Radiography, Abdominal. Time Factors. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 20082550.001).
  • [ISSN] 1130-0108
  • [Journal-full-title] Revista española de enfermedades digestivas : organo oficial de la Sociedad Española de Patología Digestiva
  • [ISO-abbreviation] Rev Esp Enferm Dig
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article
  • [Publication-country] Spain
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43. Aloysius MM, Hewavisenthi SJ, Bates TE, Rowlands BJ, Lobo DN, Zaitoun AM: Predictive value of tumor proliferative indices in periampullary cancers: Ki-67, mitotic activity index (MI) and volume corrected mitotic index (M/V) using tissue microarrays. World J Surg; 2010 Sep;34(9):2115-21
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  • The median survival for tumors of the pancreaticobiliary subtype (pancreatic ductal adenocarcinoma and cholangiocarcinoma) was 43 months in the group with an M/V score of <20, compared with 18 months for the group with a score > or =20 (P = 0.001).
  • There was no statistically significant difference in survival, based on M/V score, for tumors of the intestinal subtype (ampullary and duodenal adenocarcinoma).
  • [MeSH-major] Ampulla of Vater. Bile Duct Neoplasms / metabolism. Bile Ducts, Intrahepatic. Carcinoma, Pancreatic Ductal / metabolism. Cholangiocarcinoma / metabolism. Common Bile Duct Neoplasms / metabolism. Duodenal Neoplasms / metabolism. Ki-67 Antigen / analysis. Mitotic Index. Pancreatic Neoplasms / metabolism
  • [MeSH-minor] Humans. Immunohistochemistry. Lymphatic Metastasis. Microarray Analysis. Neoplasm Invasiveness

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  • (PMID = 20556608.001).
  • [ISSN] 1432-2323
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Ki-67 Antigen
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44. Vladov NN, Takorov IR, Mutafchiiski VM, Kjossev KT, Kazarov K, Mladenov N, Petrov N: Successful emergency pancreatoduodenectomy in a non-trauma patient. Hepatogastroenterology; 2007 Sep;54(78):1844-6
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  • [MeSH-major] Adenocarcinoma / surgery. Jaundice, Obstructive / surgery. Pancreatic Neoplasms / surgery. Pancreaticoduodenectomy / methods
  • [MeSH-minor] Adult. Duodenum / surgery. Emergencies. Female. Humans. Pancreas / surgery. Tomography, X-Ray Computed / methods. Treatment Outcome

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  • (PMID = 18019731.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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45. Lee CH, Kim PS, Lee JI, Jeong S, Lee JW, Kwon KS, Lee DH, Kim HG, Shin YW, Kim YS, Kim JM, Jeon YS: [A case of primary jejunal adenocarcinoma diagnosed by enteroscopy using pediatric colonoscope]. Korean J Gastroenterol; 2006 Nov;48(5):365-8
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  • [Title] [A case of primary jejunal adenocarcinoma diagnosed by enteroscopy using pediatric colonoscope].
  • On endoscopic examination, there was large amount of bile stained fluid in duodenum.
  • Endoscopic jejunal biopsy showed moderately differentiated adenocarcinoma.
  • Small intestinal adenocarcinoma is uncommonly encountered in clinical practice.
  • Because small intestine is relatively inaccessible via routine endoscopy, diagnosis of small intestinal neoplasm is often delayed for several months after the onset of symptoms.
  • Therefore, when a small bowel neoplasm is suspected, enteroscopy is the most useful study.
  • If enteroscope is not available, enteroscopy using pediatric colonoscope may permit earlier preoperative diagnosis.
  • We report a case of primary jejunal adenocarcinoma diagnosed by endoscopic biopsy using pediatric colonoscope.
  • [MeSH-major] Adenocarcinoma / pathology. Jejunal Neoplasms / pathology

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  • (PMID = 17132927.001).
  • [ISSN] 1598-9992
  • [Journal-full-title] The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
  • [ISO-abbreviation] Korean J Gastroenterol
  • [Language] kor
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
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46. Buecher B, Baert-Desurmont S, Leborgne J, Humeau B, Olschwang S, Frébourg T: Duodenal adenocarcinoma and Mut Y human homologue-associated polyposis. Eur J Gastroenterol Hepatol; 2008 Oct;20(10):1024-7
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  • [Title] Duodenal adenocarcinoma and Mut Y human homologue-associated polyposis.
  • Among these, duodenal polyposis, a highly prevalent manifestation of Adenomatous Polyposis Coli related familial adenomatous polypyposis, is undoubtedly part of the clinical spectrum of the disease.
  • The true association of other clinical manifestations with MAP remains questionable.We report the observation of two patients affected by MAP who developed an adenocarcinoma of the duodenum in the context of duodenal polyposis.
  • These observations emphasize the malignant potential of MAP-associated duodenal polyposis and the need to enroll these patients into an upper gastrointestinal surveillance programme.
  • [MeSH-major] Adenocarcinoma / genetics. Adenomatous Polyposis Coli / genetics. Colorectal Neoplasms / genetics. DNA Glycosylases / genetics. Duodenal Neoplasms / genetics. Mutation, Missense

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  • (PMID = 18787472.001).
  • [ISSN] 1473-5687
  • [Journal-full-title] European journal of gastroenterology & hepatology
  • [ISO-abbreviation] Eur J Gastroenterol Hepatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] EC 3.2.2.- / DNA Glycosylases; EC 3.2.2.- / mutY adenine glycosylase
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47. Lee CC, Ng WK, Lin KW, Lai TW, Li SM: Adenocarcinoma of the duodenum. Hong Kong Med J; 2008 Feb;14(1):67-9
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  • [Title] Adenocarcinoma of the duodenum.
  • Adenocarcinoma of the duodenum is an exceedingly rare disorder.

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  • (PMID = 18239248.001).
  • [ISSN] 1024-2708
  • [Journal-full-title] Hong Kong medical journal = Xianggang yi xue za zhi
  • [ISO-abbreviation] Hong Kong Med J
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
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48. Madanur MA, Battula N, Azam MO, Heaton N, Rela M: Chylous ascites after pancreatico-duodenectomy cholangiocarcinoma xenografts in nude mice. Hepatobiliary Pancreat Dis Int; 2007 Aug;6(4):416-9
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  • CA may be due to a consequence of occult obstruction of the proximal thoracic duct by malignant infiltration or tumor embolus.
  • Histologically, resected specimen confirmed pancreatic adenocarcinoma in all the patients.
  • [MeSH-major] Chylous Ascites / diagnosis. Chylous Ascites / metabolism. Duodenum / surgery. General Surgery / methods. Liver Neoplasms / diagnosis. Liver Neoplasms / pathology. Pancreas / surgery
  • [MeSH-minor] Aged. Female. Humans. Lymph Node Excision. Male. Middle Aged. Neoplasm Transplantation. Peritoneum / metabolism. Postoperative Complications. Retrospective Studies

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  • (PMID = 17690041.001).
  • [ISSN] 1499-3872
  • [Journal-full-title] Hepatobiliary & pancreatic diseases international : HBPD INT
  • [ISO-abbreviation] HBPD INT
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
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49. Westgaard A, Tafjord S, Farstad IN, Cvancarova M, Eide TJ, Mathisen O, Clausen OP, Gladhaug IP: Resectable adenocarcinomas in the pancreatic head: the retroperitoneal resection margin is an independent prognostic factor. BMC Cancer; 2008;8:5
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  • BACKGROUND: The retroperitoneal margin is frequently microscopically tumour positive in non-curative periampullary adenocarcinoma resections.
  • The periampullary cancer origin (pancreas, ampulla, distal bile duct or duodenum) was registered prospectively and reevaluated retrospectively.
  • Associations between histopathologic factors and survival were also evaluated by unadjusted and adjusted Cox regression analysis, including stepwise variable selection, in order to identify factors that independently predict a poor prognosis after periampullary adenocarcinoma resections.
  • CONCLUSION: Serial perpendicular sectioning of the retroperitoneal resection margin demonstrates that tumour involvement of this margin independently predicts survival after pancreaticoduodenectomy for adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / surgery. Pancreatic Neoplasms / surgery. Retroperitoneal Neoplasms / surgery. Retroperitoneal Space / pathology. Retroperitoneal Space / surgery

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  • (PMID = 18194510.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2249586
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50. Soulsby R, Leung E, Williams N: Malignant colo-duodenal fistula; case report and review of the literature. World J Surg Oncol; 2006;4:86
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  • [Title] Malignant colo-duodenal fistula; case report and review of the literature.
  • BACKGROUND: Colo-duodenal fistula is a rare complication of malignant and inflammatory bowel disease.
  • Cases with malignant colo-duodenal fistulae can present with symptoms from the primary, from the fistula or from metastatic disease.
  • CASE PRESENTATION: We present an unusual case of colorectal carcinoma, where a 65 year old male patient presented with diarrhoea and vomiting secondary to a malignant colo-duodenal fistula near the hepatic flexure.
  • Adenocarcinoma was confirmed on histology from a biopsy obtained during the patient's oesophageogastroduodenoscopy, and the fistula was demonstrated in his barium enema.
  • Staging computed tomography showed a locally advanced carcinoma of the proximal transverse colon, with a fistula to the duodenum and regional lymphadenopathy.
  • Colo-duodenal fistulae from colonic primaries are rare but early diagnosis may allow curative surgery.

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  • (PMID = 17147825.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1698919
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51. Ang TL, Teo EK, Fock KM: EUS-guided transduodenal biliary drainage in unresectable pancreatic cancer with obstructive jaundice. JOP; 2007;8(4):438-43
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  • [MeSH-major] Adenocarcinoma / complications. Cholestasis / surgery. Drainage / methods. Jaundice, Obstructive / etiology. Jaundice, Obstructive / surgery. Pancreatic Neoplasms / complications
  • [MeSH-minor] Aged, 80 and over. Choledochostomy. Duodenum / ultrasonography. Endosonography. Humans. Male. Middle Aged. Ultrasonography, Interventional

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  • (PMID = 17625296.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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52. Shen ZL, Wang S, Ye YJ, Wang YL, Sun KK, Yang XD, Jiang KW: Carcinosarcoma of pancreas with liver metastasis combined with gastrointestinal stromal tumour of the stomach: is there a good prognosis with the complete resection? Eur J Cancer Care (Engl); 2010 Jan 1;19(1):118-23
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  • The tumour in the head of pancreas was found to be grossly yellow-white, and it infiltrated the common bile duct and duodenum; the mass of the liver metastasis is solitary.
  • Pathologic examination showed two components separated from each other: one component was a conventional infiltrating pancreatic ductal adenocarcinoma, and the other component showed sarcomatous growth pattern composed of pleomorphic spindle cells.
  • The neoplasm of the stomach was confirmed a low malignant potential GIST by histology and immunohistochemistry.

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  • (PMID = 19486125.001).
  • [ISSN] 1365-2354
  • [Journal-full-title] European journal of cancer care
  • [ISO-abbreviation] Eur J Cancer Care (Engl)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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53. Hirono S, Tani M, Terasawa H, Kawai M, Ina S, Uchiyama K, Nakamura Y, Kakudo K, Yamaue H: A collision tumor composed of cancers of the bile duct and ampulla of Vater--immunohistochemical analysis of a rare entity of double cancer. Hepatogastroenterology; 2008 May-Jun;55(84):861-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Adenocarcinoma / pathology. Adenocarcinoma, Papillary / pathology. Ampulla of Vater / pathology. Biomarkers, Tumor / analysis. Common Bile Duct Neoplasms / pathology. Image Processing, Computer-Assisted. Imaging, Three-Dimensional. Neoplasms, Multiple Primary / pathology
  • [MeSH-minor] Aged. Cholangiopancreatography, Magnetic Resonance. Common Bile Duct / pathology. Diagnosis, Differential. Duodenum / pathology. Humans. Male. Neoplasm Invasiveness. Neoplasm Staging. Pancreaticoduodenectomy. Tomography, X-Ray Computed

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  • (PMID = 18705284.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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54. Markogiannakis H, Theodorou D, Toutouzas KG, Gloustianou G, Katsaragakis S, Bramis I: Adenocarcinoma of the third and fourth portion of the duodenum: a case report and review of the literature. Cases J; 2008;1(1):98
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenocarcinoma of the third and fourth portion of the duodenum: a case report and review of the literature.
  • Esophagogastroduodenoscopy, until the second part of duodenum, was normal.
  • Ultrasound and computed tomography demonstrated a solid mass in the distal duodenum.
  • A repeat endoscopy confirmed an ulcerative, intraluminar mass in the third and fourth part of the duodenum.
  • Segmental resection of the third and fourth portion of the duodenum was performed.
  • Histology revealed an adenocarcinoma.

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  • (PMID = 18706123.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2527500
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55. Catania C, Pelosi G, Fazio N, Biffi R, Spitaleri G, Noberasco C, Zampino MG, Maggioni A, Trifirò G, Toffalorio F, Vigna PD, De Braud F, De Pas T: A FOLFIRI-induced complete tumor response in a patient with FOLFOX-refractory metastatic duodenal adenocarcinoma. Acta Oncol; 2010;49(1):120-1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A FOLFIRI-induced complete tumor response in a patient with FOLFOX-refractory metastatic duodenal adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / drug therapy. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Duodenal Neoplasms / drug therapy
  • [MeSH-minor] Camptothecin / analogs & derivatives. Camptothecin / therapeutic use. Drug Resistance, Neoplasm / drug effects. Female. Fluorouracil / therapeutic use. Humans. Leucovorin / therapeutic use. Middle Aged. Organoplatinum Compounds / therapeutic use

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  • (PMID = 20100147.001).
  • [ISSN] 1651-226X
  • [Journal-full-title] Acta oncologica (Stockholm, Sweden)
  • [ISO-abbreviation] Acta Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Organoplatinum Compounds; Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil; XT3Z54Z28A / Camptothecin; Folfox protocol; IFL protocol
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56. Shimizu M, Kawaguchi A, Nagao S, Hozumi H, Komoto S, Hokari R, Miura S, Hatsuse K, Ogata S: A case of intraductal papillary mucinous neoplasm of the pancreas rupturing both the stomach and duodenum. Gastrointest Endosc; 2010 Feb;71(2):406-12
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  • [Title] A case of intraductal papillary mucinous neoplasm of the pancreas rupturing both the stomach and duodenum.
  • BACKGROUND: Intraductal papillary mucinous neoplasm (IPMN) of the pancreas may extend to other organs.
  • There has been no report of a benign IPMN rupturing both the stomach and duodenum.
  • Intraluminal nodular growth was observed in the duodenal gland tissue, and abnormal growth was observed in the fistula to the stomach.
  • [MeSH-major] Adenocarcinoma, Mucinous / secondary. Carcinoma, Pancreatic Ductal / secondary. Carcinoma, Papillary / secondary. Duodenal Neoplasms / secondary. Pancreatic Neoplasms / pathology. Stomach Neoplasms / secondary
  • [MeSH-minor] Aged. Cholangiopancreatography, Endoscopic Retrograde / methods. Endosonography / methods. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Neoplasm Invasiveness / pathology. Pancreaticoduodenectomy / methods. Rare Diseases. Risk Assessment. Rupture, Spontaneous / etiology. Rupture, Spontaneous / surgery. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 19922925.001).
  • [ISSN] 1097-6779
  • [Journal-full-title] Gastrointestinal endoscopy
  • [ISO-abbreviation] Gastrointest. Endosc.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 22
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57. Nathan H, Singhal S, Cameron JL: Benign pneumatosis intestinalis in the setting of celiac disease. J Gastrointest Surg; 2006 Jun;10(6):890-4
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  • We report the case of a 51-year-old man with celiac disease who underwent resection of a large duodenal adenocarcinoma.
  • Abdominal imaging revealed extensive small bowel pneumatosis and pneumoperitoneum.
  • [MeSH-minor] Adenocarcinoma / complications. Duodenal Neoplasms / complications. Humans. Male. Middle Aged. Pneumoperitoneum / complications. Pneumoperitoneum / diagnostic imaging. Tomography, X-Ray Computed

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  • (PMID = 16769547.001).
  • [ISSN] 1091-255X
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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58. Kim YK, Han YM, Kim CS: Usefulness of fat-suppressed T1-weighted MRI using orally administered superparamagnetic iron oxide for revealing ampullary carcinomas. J Comput Assist Tomogr; 2007 Jul-Aug;31(4):519-25
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  • The images were compared quantitatively by measuring the tumor-pancreas (duodenum) contrast-to-noise ratio and, qualitatively, by evaluating tumor conspicuity.
  • RESULTS: For the tumor-pancreas (duodenum) contrast-to-noise ratio, the FLASH was significantly higher than those of the dynamic set and RT-TSE (P < 0.05).
  • [MeSH-major] Adenocarcinoma / diagnosis. Ampulla of Vater. Common Bile Duct Neoplasms / diagnosis. Contrast Media. Ferric Compounds. Image Enhancement / methods. Magnetic Resonance Imaging / methods

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  • (PMID = 17882025.001).
  • [ISSN] 0363-8715
  • [Journal-full-title] Journal of computer assisted tomography
  • [ISO-abbreviation] J Comput Assist Tomogr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Ferric Compounds; 1K09F3G675 / ferric oxide
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59. Weng JM, Wu WQ, Liu QY: [Hepatoid adenocarcinoma of duodenal papilla: report of a case]. Zhonghua Bing Li Xue Za Zhi; 2009 Jul;38(7):494
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Hepatoid adenocarcinoma of duodenal papilla: report of a case].
  • [MeSH-major] Adenocarcinoma / pathology. Carcinoma, Hepatocellular / pathology. Duodenal Neoplasms / pathology
  • [MeSH-minor] Aged. Ampulla of Vater / pathology. Carcinoid Tumor / pathology. Diagnosis, Differential. Endodermal Sinus Tumor / pathology. Humans. Male. alpha-Fetoproteins / metabolism

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  • (PMID = 19781206.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / alpha-Fetoproteins
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60. Jurisić D, Doko M, Glavan E, Rosko D, Vidović D, Tomić K: Local recurrence of primary non-ampullary adenocarcinoma of duodenum after surgical treatment--a case report and a literature review. Coll Antropol; 2006 Mar;30(1):225-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Local recurrence of primary non-ampullary adenocarcinoma of duodenum after surgical treatment--a case report and a literature review.
  • Worldwide there is no general attitude on optimal surgical procedure in treatment of primary non-ampullary adenocarcinoma of duodenum, especially for early stage of duodenal cancer.
  • Some authors prefer local excision and segmental resection while others rather perform duodenopancreatic resection, even in the case of early stage of duodenal cancer with aim to avoid tumor recurrence.
  • In this paper we present a rare clinical course of a 60-year-old male patient with an endoscopically and pathohistologically proven early stage duodenal cancer that was treated by wide local excision.
  • Three years after operation, control endoscopy showed "flat" polyp in the duodenum and radical duodenopancreatic resection was performed.
  • Pathohistological examination of resected specimen showed cancer that had spread throughout the duodenal wall with metastases in the regional lymph nodes.
  • [MeSH-major] Duodenal Neoplasms / surgery. Neoplasm Recurrence, Local / surgery

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  • (PMID = 16617602.001).
  • [ISSN] 0350-6134
  • [Journal-full-title] Collegium antropologicum
  • [ISO-abbreviation] Coll Antropol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Croatia
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61. Yang WL, Yan CQ, Zhang HG, Wang FJ, Ma YL: [Surgical treatment and prognosis of cancer of hepatic flexure of colon invading the duodenum in 65 patients]. Zhonghua Zhong Liu Za Zhi; 2009 Nov;31(11):873-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Surgical treatment and prognosis of cancer of hepatic flexure of colon invading the duodenum in 65 patients].
  • OBJECTIVE: To discuss surgical treatment of right colon carcinoma of hepatic flexure invading the duodenum.
  • METHODS: Sixty-five patients with right colon carcinoma of hepatic flexure invading the duodenum, treated in our department from 1987 to 2007, were included in this study.
  • All the cases were divided into three types (local invasion, regional invasion, and cancer with internal fistula) according to duodenal defect, including local invasion (< 2.0 cm), wide invasion (> 2.0 cm) and the presence of internal fistula.
  • RESULTS: 25 patients with local invasion underwent en bloc resection of the duodenal wall.
  • Pedicled ileal flap was used to cover the large duodenal defect measuring 2.0 - 3.0 cm in 5 patients.
  • 10 underwent duodenal diverticularization.
  • CONCLUSION: The surgical procedure to be performed is usually decided according to the cancer location, extent, and duodenal defect and invasion, which are important for prolonging life time, improving of quality of life and prognosis in these patients.
  • [MeSH-major] Adenocarcinoma / surgery. Colon, Ascending / surgery. Colonic Neoplasms / surgery. Duodenum / surgery
  • [MeSH-minor] Adenocarcinoma, Mucinous / pathology. Adenocarcinoma, Mucinous / surgery. Adult. Aged. Colectomy / methods. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Invasiveness. Pancreaticoduodenectomy. Quality of Life. Retrospective Studies. Survival Rate

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  • (PMID = 20137356.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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62. Lundgren A, Strömberg E, Sjöling A, Lindholm C, Enarsson K, Edebo A, Johnsson E, Suri-Payer E, Larsson P, Rudin A, Svennerholm AM, Lundin BS: Mucosal FOXP3-expressing CD4+ CD25high regulatory T cells in Helicobacter pylori-infected patients. Infect Immun; 2005 Jan;73(1):523-31
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  • Helicobacter pylori chronically colonizes the stomach and duodenum and causes peptic ulcers or gastric adenocarcinoma in 10 to 20% of infected individuals.
  • Here we show that H. pylori-infected individuals have increased frequencies of CD4(+) CD25(high) T cells in both the stomach and duodenal mucosa compared to uninfected controls.
  • Mucosal CD4(+) CD25(high) T cells are present in individuals with asymptomatic H. pylori infections as well as in duodenal ulcer patients.
  • The frequencies of CD4(+) CD25(high) cells are also increased in the stomachs of H. pylori-infected patients with gastric adenocarcinoma, particularly in cancer-affected tissues.
  • [MeSH-minor] Adenocarcinoma / immunology. Adult. Antigens, CD. Antigens, Differentiation / analysis. CD4-Positive T-Lymphocytes / physiology. CTLA-4 Antigen. Duodenal Ulcer / immunology. Female. Forkhead Transcription Factors. Humans. Immunologic Memory. Male. Middle Aged. Stomach Neoplasms / immunology

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  • (PMID = 15618192.001).
  • [ISSN] 0019-9567
  • [Journal-full-title] Infection and immunity
  • [ISO-abbreviation] Infect. Immun.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD4; 0 / Antigens, Differentiation; 0 / CTLA-4 Antigen; 0 / CTLA4 protein, human; 0 / DNA-Binding Proteins; 0 / FOXP3 protein, human; 0 / Forkhead Transcription Factors; 0 / Receptors, Interleukin-2
  • [Other-IDs] NLM/ PMC538965
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63. Bloomston M, Chanona-Vilchis J, Ellison EC, Ramirez NC, Frankel WL: Carcinosarcoma of the pancreas arising in a mucinous cystic neoplasm. Am Surg; 2006 Apr;72(4):351-5
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  • [Title] Carcinosarcoma of the pancreas arising in a mucinous cystic neoplasm.
  • Histological examination of the neoplasm showed a 4.0 x 4.0 x 3.0-cm mucinous cystadenocarcinoma with invasive poorly differentiated carcinoma, well-differentiated squamous cell carcinoma, and sarcomatous stroma invading into the duodenum.
  • To the best of our knowledge, this is the second case of carcinosarcoma with invasive epithelial and sarcomatous areas in the background of a mucinous cystic neoplasm of the pancreas.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Carcinosarcoma / pathology. Pancreatic Neoplasms / pathology

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  • (PMID = 16676863.001).
  • [ISSN] 0003-1348
  • [Journal-full-title] The American surgeon
  • [ISO-abbreviation] Am Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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64. Ramia JM, Villar J, Palomeque A, Muffak K, Mansilla A, Garrote D, Ferrón JA: [Duodenal adenocarcinoma]. Cir Esp; 2005 Apr;77(4):208-12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Duodenal adenocarcinoma].
  • [Transliterated title] Adenocarcinoma de duodeno.
  • INTRODUCTION: Duodenal adenocarcinoma is an infrequent neoplasm.
  • Consequently, there are no large series that would allow conclusions to be reached on its diagnosis and treatment.
  • PATIENTS AND METHOD: A retrospective study (1999-2003) of five patients diagnosed with duodenal adenocarcinoma in our service was performed.
  • All patients underwent gastrointestinal endoscopy with biopsy, which revealed adenocarcinoma.
  • In all patients, the preoperative diagnosis was correct.
  • CONCLUSION: Duodenal adenocarcinoma is an infrequent tumor that is associated with various diseases.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenocarcinoma / surgery. Duodenal Neoplasms / diagnosis. Duodenal Neoplasms / surgery

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  • (PMID = 16420919.001).
  • [ISSN] 0009-739X
  • [Journal-full-title] Cirugía española
  • [ISO-abbreviation] Cir Esp
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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65. Hurtuk MG, Devata S, Brown KM, Oshima K, Aranha GV, Pickleman J, Shoup M: Should all patients with duodenal adenocarcinoma be considered for aggressive surgical resection? Am J Surg; 2007 Mar;193(3):319-24; discussion 324-5
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  • [Title] Should all patients with duodenal adenocarcinoma be considered for aggressive surgical resection?
  • BACKGROUND: Long-term survival for duodenal adenocarcinoma is inconsistent in the literature, and the biology of duodenal adenocarcinoma is poorly understood.
  • METHODS: One institution's experience with duodenal adenocarcinoma from 1984 to 2005 is reviewed.
  • CONCLUSIONS: Clinicopathologic factors important to survival in duodenal cancer are T4 tumor status and tumor size.
  • The biology of this cancer is poorly understood; therefore, aggressive resection for all duodenal adenocarcinomas is recommended for all patients medically fit to undergo resection.
  • [MeSH-major] Adenocarcinoma / surgery. Duodenal Neoplasms / surgery. Patient Selection

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  • (PMID = 17320527.001).
  • [ISSN] 1879-1883
  • [Journal-full-title] American journal of surgery
  • [ISO-abbreviation] Am. J. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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66. Will O, Carvajal-Carmona LG, Gorman P, Howarth KM, Jones AM, Polanco-Echeverry GM, Chinaleong JA, Günther T, Silver A, Clark SK, Tomlinson I: Homozygous PMS2 deletion causes a severe colorectal cancer and multiple adenoma phenotype without extraintestinal cancer. Gastroenterology; 2007 Feb;132(2):527-30
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  • BACKGROUND & AIMS: We report a patient of Indian descent with parental consanguinity, who developed 10 carcinomas and 35 adenomatous polyps at age 23 and duodenal adenocarcinoma at age 25.
  • We aimed to establish his molecular diagnosis.
  • Investigation by array-comparative genomic hybridization revealed deletion of a small region on chromosome 7.
  • [MeSH-minor] Adenomatous Polyposis Coli / diagnosis. Adult. DNA Glycosylases / genetics. Diagnosis, Differential. Duodenal Neoplasms / genetics. Fatal Outcome. Gene Expression Regulation, Neoplastic. Humans. Male. Microsatellite Instability. Mutation. Pedigree. Protein-Serine-Threonine Kinases. Proto-Oncogene Proteins / genetics. Receptors, Transforming Growth Factor beta / genetics. Severity of Illness Index. ras Proteins

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  • (PMID = 17258725.001).
  • [ISSN] 0016-5085
  • [Journal-full-title] Gastroenterology
  • [ISO-abbreviation] Gastroenterology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA-Binding Proteins; 0 / KRAS protein, human; 0 / Proto-Oncogene Proteins; 0 / Receptors, Transforming Growth Factor beta; EC 2.7.11.1 / Protein-Serine-Threonine Kinases; EC 2.7.11.30 / transforming growth factor-beta type II receptor; EC 3.2.2.- / DNA Glycosylases; EC 3.2.2.- / mutY adenine glycosylase; EC 3.6.1.- / Adenosine Triphosphatases; EC 3.6.1.- / PMS2 protein, human; EC 3.6.5.2 / ras Proteins; EC 6.5.1.- / DNA Repair Enzymes
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67. Lu B, Cai X, Lu W, Huang Y, Jin X: Laparoscopic pancreaticoduodenectomy to treat cancer of the ampulla of Vater. JSLS; 2006 Jan-Mar;10(1):97-100
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  • Three patients had duodenal papillary cancer, one had cancer of the head of the pancreas, and one had pancreatic mixed cancer (duodenal papillary cancer, hepatobiliary ductal adenocarcinoma).
  • RESULTS: The pathology diagnosis was well-differentiated duodenum papillary adenocarcinoma in 3 patients, head of pancreas endocrine small cell carcinoma in 1, and duodenum papillary adenoma with malignancy ductal intermediate differentiation adenocarcinoma in 1.
  • After surgery, 1 patient had a small amount of pancreatic leakage, another developed stress ulcer bleeding; both patients became normal after appropriate treatment.

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  • [Cites] J Gastrointest Surg. 1997 Jan-Feb;1(1):20-5; discussion 25-6 [9834326.001]
  • [Cites] Arch Surg. 2002 Feb;137(2):191-9 [11822959.001]
  • [Cites] Semin Laparosc Surg. 1998 Sep;5(3):168-79 [9787203.001]
  • (PMID = 16709370.001).
  • [ISSN] 1086-8089
  • [Journal-full-title] JSLS : Journal of the Society of Laparoendoscopic Surgeons
  • [ISO-abbreviation] JSLS
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3015677
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68. Boldery J, Gleeson J, Jordaan J: Superior mesenteric artery syndrome following small bowel resection. ANZ J Surg; 2006 Sep;76(9):861-2
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  • [Title] Superior mesenteric artery syndrome following small bowel resection.
  • It results from compression of the third part of the duodenum between the superior mesenteric artery and the aorta.
  • We present a case of superior mesenteric artery syndrome following resection of a primary adenocarcinoma of the small bowel.
  • [MeSH-major] Adenocarcinoma / surgery. Jejunal Neoplasms / surgery. Postoperative Complications / etiology. Superior Mesenteric Artery Syndrome / etiology


69. Gupte PA, Desai HG: Is the presence or absence of Helicobacter pylori in gastric mucosa a greater risk? J Assoc Physicians India; 2005 Sep;53:783-6
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  • Helicobacter pylori is a unique organism which is pathogenic for stomach-duodenum (chronic gastritis, duodenal ulcer, gastric ulcer, gastric malignancy, mucosa-associated lymphoid tissue (MALT) lymphoma) and protective for oesophagus (Barrett's oesophagus, oesophageal adenocarcinoma) at the same time in an individual.
  • [MeSH-major] Gastric Mucosa / microbiology. Gastric Mucosa / physiopathology. Helicobacter Infections / diagnosis. Helicobacter pylori / isolation & purification
  • [MeSH-minor] Adenocarcinoma / prevention & control. Barrett Esophagus / prevention & control. Disease Progression. Esophageal Neoplasms / prevention & control. Humans. Lymphoma, B-Cell, Marginal Zone / etiology. Lymphoma, B-Cell, Marginal Zone / microbiology. Prevalence. Risk Assessment. Risk Factors. Stomach Neoplasms / etiology. Stomach Neoplasms / microbiology. Stomach Ulcer / etiology. Stomach Ulcer / microbiology

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  • [CommentIn] J Assoc Physicians India. 2006 Jan;54:77; author reply 77 [16649744.001]
  • (PMID = 16334624.001).
  • [ISSN] 0004-5772
  • [Journal-full-title] The Journal of the Association of Physicians of India
  • [ISO-abbreviation] J Assoc Physicians India
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] India
  • [Number-of-references] 45
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70. Takahashi T, Ando T, Kabeshima Y, Kawakubo H, Shito M, Sugiura H, Omori T: Borderline cases between benignancy and malignancy of the duodenum diagnosed successfully by endoscopic submucosal dissection. Scand J Gastroenterol; 2009;44(11):1377-83
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  • [Title] Borderline cases between benignancy and malignancy of the duodenum diagnosed successfully by endoscopic submucosal dissection.
  • OBJECTIVE. Due to advances in endoscopic equipment, primary duodenal tumors are found more frequently than in the past.
  • We performed endoscopic submucosal dissection (ESD) to diagnose and treat four non-ampullary duodenal tumors.
  • CONCLUSIONS. Since tissue obtained from endoscopic biopsies can sometimes prove difficult for definitive histological diagnosis, ESD may play an important role in the management of cases appearing to border on malignancy.
  • In addition, ESD allows for minimally invasive treatment without sacrificing the possibility of cure for duodenal carcinoma.
  • [MeSH-major] Adenocarcinoma / diagnosis. Adenoma / diagnosis. Dissection / methods. Duodenal Neoplasms / diagnosis. Endoscopy, Gastrointestinal / methods. Intestinal Mucosa / pathology
  • [MeSH-minor] Aged. Biopsy. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Male

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  • (PMID = 19821793.001).
  • [ISSN] 1502-7708
  • [Journal-full-title] Scandinavian journal of gastroenterology
  • [ISO-abbreviation] Scand. J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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71. Bilici A, Karadag B, Doventas A, Seker M: Gastric pneumatosis intestinalis associated with malignancy: an unusual case report. World J Gastroenterol; 2009 Feb 14;15(6):758-60
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  • The most common localization is the small intestine.
  • We report on a 94-year-old man with gastric PI associated with inoperable adenocarcinoma localized in the duodenum.
  • We suggest that in patients presenting with PI, malignancy should be considered in the differential diagnosis.
  • [MeSH-major] Adenocarcinoma / diagnosis. Duodenal Neoplasms / diagnosis. Pneumatosis Cystoides Intestinalis / diagnosis. Pneumatosis Cystoides Intestinalis / radiography
  • [MeSH-minor] Aged, 80 and over. Blood Proteins / analysis. Blood Proteins / isolation & purification. Diagnosis, Differential. Fatal Outcome. Humans. Male. Stomach Diseases / diagnosis. Stomach Diseases / etiology. Stomach Diseases / radiography. Tomography, X-Ray Computed. Urine / cytology

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  • (PMID = 19222105.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Blood Proteins
  • [Other-IDs] NLM/ PMC2653449
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72. Meyer AL, Berger E, Monteiro Jr O, Alonso PA, Lerner JS: Radiographic study of patients submitted to total gastrectomy using Safatle reconstruction technique. Arq Gastroenterol; 2008 Jul-Sep;45(3):230-3
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  • The Safatle reconstruction of the gastrointestinal transit technique consists of, in short, in the association of the interposition of the jejunal loop with partial transit through the duodenum, with an inverted Roux-en-Y and with the creation of a pouch which resembles the dynamics of the stomach, achieved by duodenojejunal segment which has an antiperistalsis emptying.
  • They were summoned to perform contrasted radiographies of the esophagus-duodenum-jejunum by the videofluoroscopic method during the months of July and August, 2005.
  • [MeSH-major] Adenocarcinoma / surgery. Anastomosis, Roux-en-Y / methods. Duodenum / radiography. Jejunum / radiography. Stomach / radiography. Stomach Neoplasms / surgery

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  • (PMID = 18852952.001).
  • [ISSN] 1678-4219
  • [Journal-full-title] Arquivos de gastroenterologia
  • [ISO-abbreviation] Arq Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
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73. Inagaki M, Obara M, Suzuki S, Ishizaki A, Takahashi K, Matsumoto K, Haneda M, Tokusashi Y, Miyokawa N, Kasai S: Mucinous carcinoma of Vater's ampulla with a unique extension along the main pancreatic duct. J Hepatobiliary Pancreat Surg; 2007;14(5):518-21
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  • Abdominal computed tomography (CT) demonstrated swelling in the head of the pancreas with a mass in the duodenum.
  • A biopsy specimen of the tumor showed moderately differentiated adenocarcinoma.
  • A pylorus-preserving pancreaticoduodenectomy with a regional lymphadenectomy was performed, under a preoperative diagnosis of adenocarcinoma of Vater's ampulla with direct invasion into the head of the pancreas.
  • The resected specimen of the duodenum confirmed the presence of the mass, which measured 22 x 15 mm in size, in Vater's ampulla.
  • Microscopically, the tumor consisted of two components: moderately differentiated adenocarcinoma in the peripheral region of the tumor Vater's papilla and mucinous carcinoma in the central region of the tumor.
  • Immunohistochemically, both the moderately differentiated adenocarcinoma and the mucinous carcinoma were positive for cytokeratin 20 (CK20) and negative for cytokeratin 7 (CK7) which is the pattern of intestinal-type carcinoma of Vater's ampulla.
  • We concluded that the original site of this tumor may have been the duodenal epithelium of Vater's ampulla originally moderately differentiated adenocarcinoma-which subsequently changed to mucinous carcinoma that extended along only the MPD with microinvasion to the pancreas.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Ampulla of Vater / pathology. Common Bile Duct Neoplasms / pathology. Pancreatic Ducts / pathology. Pancreatic Neoplasms / pathology
  • [MeSH-minor] Humans. Male. Middle Aged. Neoplasm Invasiveness

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  • (PMID = 17909724.001).
  • [ISSN] 0944-1166
  • [Journal-full-title] Journal of hepato-biliary-pancreatic surgery
  • [ISO-abbreviation] J Hepatobiliary Pancreat Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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74. Nojima H, Shimizu H, Kimura F, Yoshidome H, Ohtsuka M, Kato A, Yoshitomi H, Furukawa K, Takeuchi D, Takayashiki T, Suda K, Takano S, Kuboki S, Kato M, Miyazaki M: [A resected case of non-invasive type of intraductal papillary mucinous carcinoma penetrating to the duodenum]. Gan To Kagaku Ryoho; 2010 Nov;37(12):2376-8
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  • [Title] [A resected case of non-invasive type of intraductal papillary mucinous carcinoma penetrating to the duodenum].
  • Endoscopy revealed a fistula filled with mucin in the posterior wall of the duodenum.
  • Endoscopic ultrasonography revealed dilation of the pancreatic duct and also mural nodules in the pancreatic duct, ERP demonstrated a fistula from the pancreatic duct to the duodenum.
  • We performed pancreaticoduodenectomy for main-duct IPMN penetrating to the duodenum.
  • Furthermore, a cancer invasion to the duodenum was not detected.
  • These findings suggest that the increased pressure within the pancreatic duct caused a fistula to the duodenum.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Carcinoma, Pancreatic Ductal / pathology. Duodenal Diseases / etiology. Intestinal Fistula / etiology. Pancreatic Fistula / etiology. Pancreatic Neoplasms / pathology
  • [MeSH-minor] Aged. Duodenum / pathology. Humans. Male. Pancreaticoduodenectomy

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  • (PMID = 21224578.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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75. Han SL, Cheng J, Zhou HZ, Zeng QQ, Lan SH: The surgical treatment and outcome for primary duodenal adenocarcinoma. J Gastrointest Cancer; 2008;39(1-4):46-50
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  • [Title] The surgical treatment and outcome for primary duodenal adenocarcinoma.
  • BACKGROUND: Primary duodenal adenocarcinomas (PDAC) are uncommon tumors characterized by non-specific symptoms and late diagnosis, and treatments of PDAC have some controversies.
  • METHOD: To investigate the early diagnosis and outcomes of surgical treatment of PDAC, 32 patients who were treated surgically between February 1990 and September 2006 were analyzed retrospectively.
  • CONCLUSION: PD is suggested for the tumor located at the first and second portion of the duodenum, and SR may be appropriate for the selected patients, especially for tumors of the distal duodenum.
  • [MeSH-major] Adenocarcinoma / surgery. Duodenal Neoplasms / surgery

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  • [ErratumIn] J Gastrointest Cancer. 2012 Jun;43(2):390
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  • (PMID = 19399645.001).
  • [ISSN] 1941-6628
  • [Journal-full-title] Journal of gastrointestinal cancer
  • [ISO-abbreviation] J Gastrointest Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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76. Sunagawa H, Inamine S, Watanabe M, Kawakami K, Toyama T, Zaha H, Yonaha T, Ohta M, Oshiro N, Takeshima M, Uchima H: Carcinosarcoma of the duodenum: Report of a case. Surg Today; 2009;39(10):892-6
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  • [Title] Carcinosarcoma of the duodenum: Report of a case.
  • This report describes a case of carcinosarcoma of the duodenum.
  • Carcinosarcoma of the duodenum is a very rare tumor.
  • Endoscopy demonstrated an irregularly depressed lesion (type 3) in the descending portion of the duodenum opposite to the ampulla of Vater.
  • Computed tomography showed a thickened duodenal wall and swelling of the abdominal para-aortic lymph nodes.
  • A biopsy specimen revealed a well-differentiated adenocarcinoma.
  • A diagnosis of duodenal carcinoma was made (cT3, cN1, cM1, cStage IV according to the TNM classification).
  • On microscopic examination, adenocarcinoma cells and spindle type sarcoma cells were observed separately in the descending portion of the duodenum opposite to the ampulla of Vater.
  • The adenocarcinoma cells were stained with antibodies against epithelial markers keratin and carcinoembryonic antigen for immunohistochemical analyses.
  • The pathological diagnosis of a true duodenal carcinosarcoma was thus made.
  • [MeSH-major] Carcinosarcoma / diagnosis. Duodenal Neoplasms / diagnosis
  • [MeSH-minor] Aged. Humans. Male. Neoplasm Staging

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  • (PMID = 19784730.001).
  • [ISSN] 1436-2813
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 16
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77. Chen JL, Mok KT, Tseng HH, Wang BW, Liu SI, Chen CW: Duodenal angiosarcoma: an unusual cause of severe gastrointestinal bleeding. J Chin Med Assoc; 2007 Aug;70(8):352-5
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  • [Title] Duodenal angiosarcoma: an unusual cause of severe gastrointestinal bleeding.
  • Angiosarcoma is a rare soft-tissue neoplasm that occurs most often in the skin and the subcutaneous tissues but very rarely in the gastrointestinal tract.
  • Panendoscopy revealed multiple duodenal polypoid tumors, and initial biopsy specimen showed poorly differentiated adenocarcinoma.
  • The pathology was consistent with angiosarcoma of the duodenum.
  • [MeSH-major] Duodenal Neoplasms / complications. Gastrointestinal Hemorrhage / etiology. Hemangiosarcoma / complications

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  • (PMID = 17698438.001).
  • [ISSN] 1726-4901
  • [Journal-full-title] Journal of the Chinese Medical Association : JCMA
  • [ISO-abbreviation] J Chin Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
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78. Lienert A, Bagshaw PF: Treatment of duodenal adenomas with endoscopic argon plasma coagulation. ANZ J Surg; 2007 May;77(5):371-3
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  • [Title] Treatment of duodenal adenomas with endoscopic argon plasma coagulation.
  • BACKGROUND: Surgical resection has been the standard treatment for duodenal adenomas.
  • METHODS: We retrospectively identified patients with non-ampullary duodenal adenomas without a polyposis syndrome and who were treated endoscopically between 1st January 1999 and 31st December 2003.
  • No patient developed duodenal adenocarcinoma during the study period.
  • CONCLUSION: Argon plasma coagulation may be safe and effective for the treatment of duodenal adenomas, but further research is required.
  • [MeSH-major] Adenoma / surgery. Duodenal Neoplasms / surgery. Endoscopy, Gastrointestinal. Laser Coagulation
  • [MeSH-minor] Aged. Aged, 80 and over. Argon. Follow-Up Studies. Humans. Middle Aged. Neoplasm Recurrence, Local. Postoperative Complications. Retrospective Studies. Treatment Outcome

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  • (PMID = 17497979.001).
  • [ISSN] 1445-1433
  • [Journal-full-title] ANZ journal of surgery
  • [ISO-abbreviation] ANZ J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 67XQY1V3KH / Argon
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79. Mackey R, Walsh RM, Chung R, Brown N, Smith A, Church J, Burke C: Pancreas-sparing duodenectomy is effective management for familial adenomatous polyposis. J Gastrointest Surg; 2005 Nov;9(8):1088-93; discussion 1093
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  • Duodenal adenocarcinoma remains the leading cause of cancer death in familial adenomatous polyposis patients following colectomy.
  • Invasive cancer was found in the distal duodenum in one patient.
  • Pancreas-sparing duodenectomy represents a definitive treatment for advanced duodenal polyposis and can obviate the need for pancreaticoduodenectomy.
  • [MeSH-major] Adenomatous Polyposis Coli / surgery. Duodenal Neoplasms / surgery. Duodenum / surgery. Pancreaticoduodenectomy / methods
  • [MeSH-minor] Female. Humans. Length of Stay / statistics & numerical data. Male. Middle Aged. Neoplasm Invasiveness. Postoperative Complications. Treatment Outcome

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  • (PMID = 16269379.001).
  • [ISSN] 1091-255X
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
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80. Afridi SP, Mohib Y, Shafiq-ur-Rahman: Primary adenocarcinoma of duodenum. J Coll Physicians Surg Pak; 2010 Feb;20(2):130-1
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  • [Title] Primary adenocarcinoma of duodenum.
  • Primary duodenal adenocarcinoma (PDC) of the distal half of duodenum is extremely rare.
  • We report a case of a young male with adenocarcinoma of third and fourth part of duodenum presenting with long standing proximal small bowel obstruction with associated weight loss and anemia.
  • Esophago-gastro-duodeno-scopy showed a fungating intraluminal growth in third and fourth part of the duodenum.
  • Computed tomography also showed a solid mass in the third and fourth part of the duodenum.
  • Computed tomography also showed a solid mass in the third and fourth part of the duodenum.
  • Segmental resection of the third and fourth part of the duodenum was performed with single layer extra mucosal duodenojejunal anastomosis.
  • [MeSH-major] Adenocarcinoma / pathology. Duodenal Neoplasms / pathology

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  • (PMID = 20378043.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
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81. Anastasopoulos G, Marinis A, Konstantinidis C, Theodosopoulos T, Fragulidis G, Vassiliou I: Adenocarcinoma of the third portion of the duodenum in a man with CREST syndrome. World J Surg Oncol; 2008;6:106
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  • [Title] Adenocarcinoma of the third portion of the duodenum in a man with CREST syndrome.
  • This is the first report of a primary adenocarcinoma of the third portion of the duodenum in a patient with CREST syndrome.
  • An ulcerative lesion in the third portion of the duodenum was revealed during duodenoscopy, with a diagnosis of adenocarcinoma on biopsy specimen histology.
  • CONCLUSION: CREST syndrome has been associated with colon cancer, gastric polyps, familial adenomatous polyposis (FAP) syndrome and Crohn's disease; however, this is the first report of a primary adenocarcinoma of the duodenum in a patient with CREST syndrome.
  • [MeSH-major] Adenocarcinoma / complications. CREST Syndrome / complications. Duodenal Neoplasms / complications

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82. Spalding DR, Isla AM, Thompson JN, Williamson RC: Pancreas-sparing distal duodenectomy for infrapapillary neoplasms. Ann R Coll Surg Engl; 2007 Mar;89(2):130-5
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  • INTRODUCTION: For neoplasms that arise in the third and fourth parts of the duodenum (D(3), D(4)), a duodenectomy that preserves the pancreas can provide adequate tumour clearance while avoiding the additional dissection and risk of the common alternative, pancreatoduodenectomy.
  • PATIENTS AND METHODS: Pancreas-sparing distal duodenectomy (PSDD) was performed in 14 patients with infrapapillary duodenal neoplasms between 1991-2002, and the clinical outcome is reviewed.
  • The operation entails careful separation of the lower pancreatic head from D(3), complete mobilisation of the ligament of Treitz and end-to-end duodenojejunal anastomosis 1-3 cm below the major duodenal papilla.
  • There were 11 malignant neoplasms (adenocarcinoma 5, stromal tumour 4, recurrent seminoma 1, plasmacytoma 1), 2 benign neoplasms (villous adenoma, lipoma) and 1 patient with steroid-induced ulceration.
  • Median operation time was 240 min and median blood loss 1197 ml, being greater for malignant than benign lesions (1500 ml versus 700 ml).
  • CONCLUSIONS: Provided there is a minimum 1-cm clearance at the papilla, PSDD is a useful alternative to formal pancreatoduodenectomy in patients with unusual neoplasms arising from the third and fourth parts of the duodenum.
  • [MeSH-major] Adenocarcinoma, Papillary / surgery. Duodenal Neoplasms / surgery. Pancreas / surgery. Pancreaticoduodenectomy / methods

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  • (PMID = 17346405.001).
  • [ISSN] 1478-7083
  • [Journal-full-title] Annals of the Royal College of Surgeons of England
  • [ISO-abbreviation] Ann R Coll Surg Engl
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1964558
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83. Sierra Ausin M, Linares Torres P, Alvarez Posadilla M, Díez Rodríguez R, Rascarachi G, Arias Rodríguez L, Olcoz Goñi JL: [Signet-ring cell adenocarcinoma of the duodenal bulb]. Gastroenterol Hepatol; 2008 Feb;31(2):107-8
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  • [Title] [Signet-ring cell adenocarcinoma of the duodenal bulb].
  • [Transliterated title] Adenocarcinoma del bulbo duodenal con células en anillo de sello.
  • [MeSH-major] Carcinoma, Signet Ring Cell / diagnosis. Duodenal Neoplasms / diagnosis

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  • (PMID = 18279652.001).
  • [ISSN] 0210-5705
  • [Journal-full-title] Gastroenterología y hepatología
  • [ISO-abbreviation] Gastroenterol Hepatol
  • [Language] spa
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Spain
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84. Watanabe M, Yamazaki K, Yajima S, Tsuchiya M, Otsuka Y, Tamura A, Oshima Y, Kaneko H, Shimokawa K: Fourteen-years of disease-free survival in a patient with advanced gallbladder carcinoma after radical resection: a case report. Hepatogastroenterology; 2009 Mar-Apr;56(90):335-8
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  • A preoperative diagnosis of advanced GBC with invasion into the liver bed, the abdominal wall, the duodenum, the common bile duct and the hepatic flexure of the colon were made.
  • On histopathology, the resected specimen showed a well-differentiated adenocarcinoma and the 56 resected lymph nodes showed no evidence of metastasis.
  • [MeSH-major] Adenocarcinoma / surgery. Gallbladder Neoplasms / diagnosis. Gallbladder Neoplasms / surgery
  • [MeSH-minor] Cholecystectomy. Colectomy. Colonoscopy. Contrast Media. Diagnosis, Differential. Disease-Free Survival. Female. Humans. Middle Aged. Pancreaticoduodenectomy. Tomography, X-Ray Computed

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  • (PMID = 19579593.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Contrast Media
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85. Tonelli F, Bargellini T, Leo F, Nesi G: Duodenal adenocarcinoma arising at the strictureplasty site in a patient with Crohn's disease: report of a case. Int J Colorectal Dis; 2009 Apr;24(4):475-7
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  • [Title] Duodenal adenocarcinoma arising at the strictureplasty site in a patient with Crohn's disease: report of a case.
  • [MeSH-major] Crohn Disease / complications. Crohn Disease / surgery. Duodenal Neoplasms / etiology


86. Yamaoka K, Inatsugi N, Yoshikawa S, Masuda T, Uchida H, Kuge H, Yokotani T, Yamaguchi T, Kawaguchi C, Shimobayashi T, Inagaki M, Matsuoka M, Tatsumi K, Saraya T, Otsuji T, Yamochi Y, Yamanishi K, Enomoto Y, Nonomura A, Sho M, Nakajima Y: [A surgical (pancreatoduodenectomy) case of lymph node metastatic recurrence of colon cancer after chemotherapy]. Gan To Kagaku Ryoho; 2010 Nov;37(12):2346-8
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  • A woman in her fifties underwent a right hemicolectomy (D3) for cancer of the ascending colon in October 2007, definitively and pathologically diagnosed as papillary adenocarcinoma invading to the subserosa, and no metastasis was detected to lymph node.
  • [MeSH-major] Adenocarcinoma, Papillary / pathology. Adenocarcinoma, Papillary / therapy. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Colonic Neoplasms / pathology. Colonic Neoplasms / therapy. Lymphatic Metastasis / pathology. Pancreatic Neoplasms / secondary. Pancreatic Neoplasms / therapy
  • [MeSH-minor] Duodenum / surgery. Female. Fluorouracil / therapeutic use. Humans. Leucovorin / therapeutic use. Middle Aged. Neoplasm Recurrence, Local. Organoplatinum Compounds / therapeutic use. Pancreatectomy

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  • (PMID = 21224568.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Organoplatinum Compounds; Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil; Folfox protocol
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87. Kovacs DJ, Berk T: Gastrointestinal bleeding of obscure origin undetected by multiple tests for fecal occult blood and diagnosed only by capsule endoscopy: a case report. J Am Board Fam Med; 2006 Nov-Dec;19(6):641-2
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  • We report the case of a middle-aged woman with gastrointestinal bleeding of obscure origin who had 9 stool specimens that tested negative for occult blood but was found to have adenocarcinoma of the distal duodenum on capsule endoscopy.
  • [MeSH-major] Capsule Endoscopy. Gastrointestinal Hemorrhage / diagnosis. Occult Blood

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  • (PMID = 17090799.001).
  • [ISSN] 1557-2625
  • [Journal-full-title] Journal of the American Board of Family Medicine : JABFM
  • [ISO-abbreviation] J Am Board Fam Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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88. Goh BK, Yeo AW, Koong HN, Ooi LL, Wong WK: Laparotomy for acute complications of gastrointestinal metastases from lung cancer: is it a worthwhile or futile effort? Surg Today; 2007;37(5):370-4
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  • The sites of symptomatic GIT metastases include the ileum (n = 3), jejunum (n = 3), cecum (n = 1), duodenum (n = 2) and stomach (n = 2) and the patients presented with obstruction (n = 2), hemorrhage (n = 3), intussusception (n = 3) and perforation (n = 1).
  • The median time of symptomatic GIT metastases from initial presentation was 2 months (range, 0-8 months) and the histological subtypes of the lung cancer were squamous cell carcinoma (n = 3), large cell carcinoma (n = 3), adenocarcinoma (n = 1), pleomorphic carcinoma (n = 1) and pleomorphic with adenocarcinoma (n = 1).
  • These included a small bowel resection with primary anastomosis (n = 5), a subtotal gastrectomy with an extended right hemicolectomy (n = 1), a gastrojejunostomy (n = 1), a right hemicolectomy (n = 1), and an ulcerectomy with under-running of ulcers (n = 1).
  • CONCLUSION: Gastrointestinal tract metastases should always be considered in the differential diagnosis of lung cancer patients presenting with an acute abdomen.

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  • (PMID = 17468816.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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89. Farhat MH, Shamseddine AI, Barada KA: Small bowel tumors: clinical presentation, prognosis, and outcome in 33 patients in a tertiary care center. J Oncol; 2008;2008:212067
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  • [Title] Small bowel tumors: clinical presentation, prognosis, and outcome in 33 patients in a tertiary care center.
  • Introduction. Small bowel cancers are rare.
  • Methods. This is a retrospective study of the medical records of 33 patients with small bowel cancers treated at the American University of Beirut-Medical Center over a 20-year period.
  • Lymphoma was the most common malignant tumor (36.4%), followed by adenocarcinoma (33.3%), leiomyosarcoma (15.2%), gastrointestinal stromal tumors (12.1%), and neuroendocrine tumors (3.0%).
  • Tumors were located in the duodenum in 30% of patients, jejunum in 33%, and ileum in 36%.
  • Conclusion. Small bowel cancers are difficult to diagnose because of the nonspecific symptoms.
  • Adenocarcinoma and duodenal location have the worst 5-year survival in contrast to stromal tumors and those with ileal location which have the best survival.

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  • (PMID = 19266087.001).
  • [ISSN] 1687-8450
  • [Journal-full-title] Journal of oncology
  • [ISO-abbreviation] J Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
  • [Other-IDs] NLM/ PMC2648638
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90. Budiharto T, Haustermans K, Van Cutsem E, Van Steenbergen W, Topal B, Aerts R, Ectors N, Bielen D, Vanbeckevoort D, Goethals L, Verslype C: A phase I radiation dose-escalation study to determine the maximal dose of radiotherapy in combination with weekly gemcitabine in patients with locally advanced pancreatic adenocarcinoma. Radiat Oncol; 2008;3:30
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  • [Title] A phase I radiation dose-escalation study to determine the maximal dose of radiotherapy in combination with weekly gemcitabine in patients with locally advanced pancreatic adenocarcinoma.
  • The mean dose to the duodenum was significantly higher in the 54 Gy cohort (38.45 Gy vs. 51.82 Gy; p = 0.001).
  • Considering the good patient outcomes, there might be a role for the investigation of a fixed dose of gemcitabine and concurrent RT with small fractions (1.8 Gy/day) in borderline resectable or unresectable non-metastatic locally advanced pancreatic cancer.
  • [MeSH-major] Adenocarcinoma / drug therapy. Adenocarcinoma / radiotherapy. Antimetabolites, Antineoplastic / administration & dosage. Deoxycytidine / analogs & derivatives. Pancreatic Neoplasms / drug therapy. Pancreatic Neoplasms / radiotherapy. Radiotherapy / methods
  • [MeSH-minor] Adult. Aged. Cohort Studies. Combined Modality Therapy. Female. Humans. Male. Maximum Tolerated Dose. Middle Aged. Neoplasm Metastasis

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  • (PMID = 18808686.001).
  • [ISSN] 1748-717X
  • [Journal-full-title] Radiation oncology (London, England)
  • [ISO-abbreviation] Radiat Oncol
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0W860991D6 / Deoxycytidine; B76N6SBZ8R / gemcitabine
  • [Other-IDs] NLM/ PMC2557003
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91. Xu GQ, Wu YQ, Wang LJ, Chen HT: Values of endoscopic ultrasonography for diagnosis and treatment of duodenal protruding lesions. J Zhejiang Univ Sci B; 2008 Apr;9(4):329-34
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  • [Title] Values of endoscopic ultrasonography for diagnosis and treatment of duodenal protruding lesions.
  • OBJECTIVE: The diagnoses of patients with duodenal protruding lesions are difficult when using conventional examinations such as computed tomography (CT) and conventional endoscope etc.
  • Thus, we investigated the clinical value of endoscopic ultrasonography (EUS) with miniature ultrasonic probes on the diagnosis and treatment of duodenal protruding lesions.
  • METHODS: Patients with duodenal protruding lesions who were indicated for EUS were examined by EUS with 12 approximately 15 MHz miniature ultrasonic probes and double-cavity electronic endoscope.
  • According to diagnosis of EUS, those patients were indicated for biopsy and treatment received biopsy, endoscopic resection or surgical excision.
  • The postoperative histological results were compared with the preoperative diagnosis of EUS.
  • RESULTS: A total of 169 patients with duodenal protruding lesions were examined by EUS, of which 40 were diagnosed with cysts, 36 with inflammatory protruding or polyp, 25 with Brunner's gland adenoma, 19 with ectopic pancreas, 17 with gastrointestinal stromal tumor, 12 with extrinsic compression, 12 with minor papilla, 6 with lipoma, 1 with adenocarcinoma and 1 with lymphoma.
  • The postoperative histological results of 70 patients were completely consistent with the preoperative diagnosis of EUS, with 93.33% diagnostic accuracy.
  • The results of follow-up with EUS indicated that duodenal cyst, Brunner's gland adenoma, ectopic pancreas, gastrointestinal stromal tumor and lipoma remained unchanged within 1 approximately 3 years.
  • CONCLUSION: EUS is an effective and reliable diagnostic method for duodenal protruding lesions.
  • [MeSH-major] Digestive System Neoplasms / diagnosis. Digestive System Neoplasms / ultrasonography. Duodenal Diseases / diagnosis. Duodenal Diseases / ultrasonography. Duodenum / pathology. Duodenum / ultrasonography. Endoscopy / methods. Neoplasms / diagnosis. Neoplasms / ultrasonography. Ultrasonography / methods

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  • (PMID = 18381809.001).
  • [ISSN] 1673-1581
  • [Journal-full-title] Journal of Zhejiang University. Science. B
  • [ISO-abbreviation] J Zhejiang Univ Sci B
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2276677
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92. McCarthy TC, Li X, Sinal CJ: Vitamin D receptor-dependent regulation of colon multidrug resistance-associated protein 3 gene expression by bile acids. J Biol Chem; 2005 Jun 17;280(24):23232-42
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  • Analysis of Mrp3 mRNA levels in various mouse tissues with known relevance and/or exposure to bile acids revealed the highest levels of basal expression in the colon followed in order by the liver, duodenum, jejunum, ileum, and kidney.
  • Reduction of endogenous VDR expression in colon adenocarcinoma MCA-38 cells by siRNA transfection was associated with reduced constitutive and inducible expression of the Mrp3 gene.
  • [MeSH-minor] Animals. Base Sequence. Calcitriol / metabolism. Cell Line, Tumor. Cloning, Molecular. DNA, Complementary / metabolism. Dimerization. Dose-Response Relationship, Drug. Exons. Gene Deletion. Gene Expression Regulation. Genes, Reporter. Humans. Intestines / metabolism. Kidney / metabolism. Ligands. Liver / metabolism. Male. Mice. Mice, Inbred C57BL. Models, Biological. Models, Genetic. Molecular Sequence Data. Mutagenesis, Site-Directed. Promoter Regions, Genetic. RNA Interference. RNA, Messenger / metabolism. RNA, Small Interfering / metabolism. Transfection

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  • (PMID = 15824121.001).
  • [ISSN] 0021-9258
  • [Journal-full-title] The Journal of biological chemistry
  • [ISO-abbreviation] J. Biol. Chem.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Bile Acids and Salts; 0 / DNA, Complementary; 0 / Ligands; 0 / Multidrug Resistance-Associated Proteins; 0 / RNA, Messenger; 0 / RNA, Small Interfering; 0 / Receptors, Calcitriol; 0 / multidrug resistance-associated protein 3; FXC9231JVH / Calcitriol
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93. Ogoshi K, Okamoto Y, Nabeshima K, Morita M, Nakamura K, Iwata K, Soeda J, Kondoh Y, Makuuchi H: Focus on the conditions of resection and reconstruction in gastric cancer. What extent of resection and what kind of reconstruction provide the best outcomes for gastric cancer patients? Digestion; 2005;71(4):213-24
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  • To assess the roles of the extent of gastric resection and duodenal food passage reconstruction in gastric cancer, we examined a consecutive series of 1,061 patients who underwent total or partial (proximal and distal) gastrectomies with or without duodenal food passage reconstruction between August of 1974 and January of 2002, and received gastrectomies with D2-3 lymph node dissection.
  • Additionally, patients with duodenal food passage reconstruction or double tract reconstruction also showed significantly better survival rates than those without duodenal food reconstruction in stages 1A (10-year survival: 86.4 and 82.5 vs. 61.7%), 1B (69.9 and 90.6 vs. 54.1%), 2 (60.5 and 63.3 vs. 16.5%), and 3A (39.9 and 47.4 vs. 23.1%).
  • In multivariate analysis, the independent prognostic factors were age at operation, depth of tumor, duodenal food passage reconstruction, and lymph node metastasis.
  • Our results indicate that both the extent of gastric resection and duodenal food passage reconstruction were important factors in the outcome of gastric cancer patients, and that surgeons should perform minimal gastric resection with preservation of the duodenal food passage when the gastric stump is tumor-free.
  • [MeSH-major] Adenocarcinoma / surgery. Duodenum / surgery. Gastrectomy / methods. Reconstructive Surgical Procedures / methods. Stomach Neoplasms / surgery


94. Uvarov IB, Genrikh SR, Liutov DA, Shatov MN, Onopriev VI: [Primary jejunogastroplasty with end-loop gastroenteroanastomosis and inclusion of the duodenum in distal resection of the stomach (surgical technology and functional results)]. Vestn Khir Im I I Grek; 2008;167(1):37-42
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  • [Title] [Primary jejunogastroplasty with end-loop gastroenteroanastomosis and inclusion of the duodenum in distal resection of the stomach (surgical technology and functional results)].
  • Complex examination of 57 patients (25 patients of the main group, and 32 controls) has shown that the proposed technology of primary JGP can reliably prevent gastroesophageal and duodeno-enterogastic reflux, creates conditions for the portion-rhythmical evacuation of food from the gastric stump.
  • [MeSH-major] Anastomosis, Roux-en-Y / methods. Duodenum / surgery. Gastroplasty. Jejunum / surgery. Stomach / surgery
  • [MeSH-minor] Adenocarcinoma / epidemiology. Adenocarcinoma / surgery. Adult. Aged. Female. Gastrointestinal Neoplasms / epidemiology. Gastrointestinal Neoplasms / surgery. Humans. Male. Middle Aged. Treatment Outcome

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  • (PMID = 18411666.001).
  • [ISSN] 0042-4625
  • [Journal-full-title] Vestnik khirurgii imeni I. I. Grekova
  • [ISO-abbreviation] Vestn. Khir. Im. I. I. Grek.
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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95. Miller AD, Kramer JA, Lin KC, Knight H, Martinot A, Mansfield KG: Small intestinal adenocarcinoma in common marmosets (Callithrix jacchus). Vet Pathol; 2010 Sep;47(5):969-76
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  • [Title] Small intestinal adenocarcinoma in common marmosets (Callithrix jacchus).
  • Small intestinal adenocarcinomas are uncommon neoplasms that are rarely reported in nonhuman primates.
  • Herein the authors report the clinical, histologic, immunohistochemical, and molecular characteristics of small intestinal adenocarcinoma in 10 common marmosets (Callithrix jacchus).
  • Retrospective analysis of necropsy records revealed small intestinal carcinoma to be the most common neoplastic cause of morbidity and mortality in aged common marmosets.
  • Nine of 10 (90%) tumors arose within the proximal small intestine near the interface with the duodenum.
  • The tumors described in this population illustrate comparable features to human cases of small intestine carcinoma and may serve as a potential animal model for small intestinal carcinomas.

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  • (PMID = 20460447.001).
  • [ISSN] 1544-2217
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] ENG
  • [Grant] United States / NCRR NIH HHS / RR / T32 RR007000-35; United States / NCRR NIH HHS / RR / P51 RR000168-50; United States / NCRR NIH HHS / RR / T32 RR007000; United States / NCRR NIH HHS / RR / RR00168; United States / NCRR NIH HHS / RR / P51 RR000168; United States / NCRR NIH HHS / RR / K26 RR000168; United States / NCRR NIH HHS / RR / RR07000
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm
  • [Other-IDs] NLM/ NIHMS235944; NLM/ PMC2955325
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96. Zhang T, Zhang F, Han Y, Gu Z, Zhou Y, Cheng Q, Zhu Y, Zhang C, Wang Y: A rat surgical model of esophageal metaplasia and adenocarcinoma-induced by mixed reflux of gastric acid and duodenal contents. Dig Dis Sci; 2007 Nov;52(11):3202-8
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  • [Title] A rat surgical model of esophageal metaplasia and adenocarcinoma-induced by mixed reflux of gastric acid and duodenal contents.
  • Recent clinical data have revealed that mixed reflux (MR) of gastric acid and duodenal contents frequently occurs in patients with gastroesophageal reflux disease and a progressive increase of MR occurs with increasing severity across gastroesophageal reflux disease.
  • Herein we report a novel rat surgical model in which esophageal metaplasia and adenocarcinoma develop as complications of MR.
  • Severe inflammatory and proliferative changes, high prevalence of esophageal metaplasia (78%), and adenocarcinoma (50%) were observed in the lower part of the esophagus of rats 20 weeks after surgery.
  • The resulting esophageal lesions resembled those described in humans and supported a progression from intestinal metaplasia to dysplasia and, ultimately, esophageal adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / surgery. Duodenostomy / methods. Esophageal Neoplasms / surgery. Esophagostomy / methods. Esophagus / pathology. Gastroesophageal Reflux / complications. Jejunostomy / methods
  • [MeSH-minor] Animals. Disease Models, Animal. Disease Progression. Duodenum / secretion. Gastric Acid / secretion. Male. Metaplasia / etiology. Metaplasia / pathology. Metaplasia / surgery. Models, Anatomic. Rats. Rats, Sprague-Dawley

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  • (PMID = 17393326.001).
  • [ISSN] 0163-2116
  • [Journal-full-title] Digestive diseases and sciences
  • [ISO-abbreviation] Dig. Dis. Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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97. Lee HG, You DD, Paik KY, Heo JS, Choi SH, Choi DW: Prognostic factors for primary duodenal adenocarcinoma. World J Surg; 2008 Oct;32(10):2246-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Prognostic factors for primary duodenal adenocarcinoma.
  • BACKGROUND: The aim of this study was to review the clinical features of primary duodenal adenocarcinoma (PDA) patients and to identify factors that influence survival.
  • [MeSH-major] Adenocarcinoma / mortality. Duodenal Neoplasms / mortality
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Kaplan-Meier Estimate. Male. Middle Aged. Multivariate Analysis. Neoplasm Staging. Prognosis. Survival Rate. Treatment Outcome

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  • (PMID = 18668288.001).
  • [ISSN] 0364-2313
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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98. Yasumoto T, Yamamoto T, Tomimaru Y, Ide Y, Matsunaga H, Ikeda N, Maruyama K, Yokouchi H, Okada K, Ota H, Kinuta M, Murata K: [Transcatheter arterial embolization for the continuous bleeding from duodenal carcinoma--a case report]. Gan To Kagaku Ryoho; 2007 Nov;34(12):2141-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Transcatheter arterial embolization for the continuous bleeding from duodenal carcinoma--a case report].
  • We report a case of duodenal carcinoma with continuous bleeding that was successfully treated with transcatheter arterial embolization using gelatin sponge particles.
  • Upper gastrointestinal endoscopy revealed active bleeding from a duodenal tumor.
  • The biopsy of the specimens was made and showed duodenal adenocarcinoma.
  • The patient was considered to be inoperable because of the liver abscess and transcatheter arterial embolization of an anterior superior pancreaticoduodenal artery through an inferior pancreaticoduodenal artery was performed for the continuous bleeding from duodenal carcinoma not completely treated by endoscopic hemostasis or frequent transfusion.
  • Transcatheter arterial embolization for a continuous bleeding from duodenal carcinoma is a feasible and effective method as a noninvasive therapy when it is unabled to be treated by surgical resection or endoscopic therapy.
  • [MeSH-major] Arteries. Catheterization / methods. Duodenal Neoplasms / surgery. Duodenal Neoplasms / therapy. Embolization, Therapeutic. Hemorrhage / surgery

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  • (PMID = 18219925.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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99. Fishman MN, Garrett CR, Simon GR, Chiappori AA, Lush RM, Dinwoodie WR, Mahany JJ, Dellaportas AM, Cantor A, Gollerki A, Cohen MB, Sullivan DM: Phase I study of the taxane BMS-188797 in combination with carboplatin administered every 3 weeks in patients with solid malignancies. Clin Cancer Res; 2006 Jan 15;12(2):523-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Two radiographic partial responses were observed: one patient with duodenal adenocarcinoma and one patient with esophageal adenocarcinoma (time on study, 19 and 30 weeks, respectively).

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  • (PMID = 16428495.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / BMS188797; 0 / Taxoids; BG3F62OND5 / Carboplatin
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100. Zippi M, Traversa G, Masini A, De Felici I, Febbraro I, Mattei E, Pica R, Bertoldi I, Occhigrossi G: Placement of two overlapping uncovered metallic stents for malignant gastric outlet and duodenal obstruction due to colon cancer. Dig Liver Dis; 2006 Aug;38(8):612-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Placement of two overlapping uncovered metallic stents for malignant gastric outlet and duodenal obstruction due to colon cancer.
  • Malignant obstruction of the gastric outlet and duodenum is frequently due to extrinsic involvement by tumors from contiguous organs, in particular from pancreas and gallbladder.
  • The treatment of malignant gastroduodenal stenoses is difficult.
  • Many patients have advanced malignant disease and are too ill to undergo surgical approach.
  • We report a case in which self-expanding metallic stents were placed for stenoses of the gastric outlet and duodenum due to a colon cancer.
  • [MeSH-major] Adenocarcinoma / complications. Colonic Neoplasms / complications. Duodenal Obstruction / etiology. Duodenal Obstruction / surgery. Gastric Outlet Obstruction / etiology. Gastric Outlet Obstruction / surgery. Stents

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  • (PMID = 16828352.001).
  • [ISSN] 1590-8658
  • [Journal-full-title] Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
  • [ISO-abbreviation] Dig Liver Dis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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